ORF_ID e_value Gene_name EC_number CAZy COGs Description
OPEFLCOJ_00001 6e-74 yuiD S protein conserved in bacteria
OPEFLCOJ_00002 1.9e-214 solA 1.5.3.1 E FAD dependent oxidoreductase
OPEFLCOJ_00003 3.1e-220 FOXRED 1.5.3.1 E FAD dependent oxidoreductase
OPEFLCOJ_00004 1.2e-280 ycbD 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OPEFLCOJ_00005 6.2e-171 4.3.1.12 E ornithine cyclodeaminase
OPEFLCOJ_00007 1.3e-138 S Metallo-beta-lactamase superfamily
OPEFLCOJ_00008 6.6e-15 S Protein of unknown function (DUF3006)
OPEFLCOJ_00012 7.3e-33 S AP2 domain protein
OPEFLCOJ_00013 4.2e-15
OPEFLCOJ_00016 2e-50 lyc 3.2.1.17 M lysozyme activity
OPEFLCOJ_00017 2.6e-44
OPEFLCOJ_00018 3.2e-139 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
OPEFLCOJ_00020 3.5e-41
OPEFLCOJ_00021 6.9e-42
OPEFLCOJ_00022 4.1e-105 S Phage minor structural protein
OPEFLCOJ_00023 6.1e-169 S Phage tail protein
OPEFLCOJ_00024 1.3e-132 L Transglycosylase SLT domain
OPEFLCOJ_00025 8.5e-52 S Bacteriophage Gp15 protein
OPEFLCOJ_00027 1.1e-48 N Belongs to the glycosyl hydrolase family 6
OPEFLCOJ_00028 6.1e-39 S Minor capsid protein from bacteriophage
OPEFLCOJ_00029 6.2e-31 S Minor capsid protein
OPEFLCOJ_00030 3.6e-07 S Minor capsid protein
OPEFLCOJ_00031 5.2e-15
OPEFLCOJ_00032 6.7e-13
OPEFLCOJ_00033 3e-125
OPEFLCOJ_00034 5.9e-22
OPEFLCOJ_00035 9.5e-21
OPEFLCOJ_00036 1.5e-128 M Phage minor capsid protein 2
OPEFLCOJ_00037 2.3e-154 S portal protein
OPEFLCOJ_00038 7.9e-201 S Terminase RNAseH like domain
OPEFLCOJ_00039 1.3e-81 yqaS L DNA packaging
OPEFLCOJ_00041 6.5e-43 L Transposase
OPEFLCOJ_00042 3e-21 S HNH endonuclease
OPEFLCOJ_00043 2.5e-07
OPEFLCOJ_00044 2.6e-13 cysH 1.8.4.10, 1.8.4.8 EH Belongs to the PAPS reductase family. CysH subfamily
OPEFLCOJ_00045 6.5e-11 S Pfam:DUF2276
OPEFLCOJ_00046 8.1e-11
OPEFLCOJ_00047 5.7e-47 L crispr-associated protein
OPEFLCOJ_00049 1.1e-07
OPEFLCOJ_00054 2.5e-13 S Protein of unknown function (DUF3954)
OPEFLCOJ_00055 3.2e-11 V N-6 DNA Methylase
OPEFLCOJ_00057 5.8e-53 S Protein of unknown function (DUF1064)
OPEFLCOJ_00058 6e-44 S dUTPase
OPEFLCOJ_00062 1.7e-90 xkdC L Bacterial dnaA protein
OPEFLCOJ_00063 1.3e-13 xkdC L Bacterial dnaA protein
OPEFLCOJ_00064 1.7e-28 L Replication initiation and membrane attachment
OPEFLCOJ_00065 4.6e-123 recT L RecT family
OPEFLCOJ_00066 1.8e-138 yqaJ L YqaJ-like viral recombinase domain
OPEFLCOJ_00067 3.3e-11 S Hypothetical protein Yqai
OPEFLCOJ_00072 1.4e-15
OPEFLCOJ_00073 7.3e-15 S Helix-turn-helix domain
OPEFLCOJ_00074 7.8e-58 K BRO family, N-terminal domain
OPEFLCOJ_00075 1.3e-16 2.3.1.19 K sequence-specific DNA binding
OPEFLCOJ_00076 1.8e-18 K Helix-turn-helix XRE-family like proteins
OPEFLCOJ_00077 4.5e-16 S IrrE N-terminal-like domain
OPEFLCOJ_00079 6e-73 yokF 3.1.31.1 L RNA catabolic process
OPEFLCOJ_00080 2.3e-109 L Belongs to the 'phage' integrase family
OPEFLCOJ_00082 3.7e-182 yugO P COG1226 Kef-type K transport systems
OPEFLCOJ_00083 1.1e-258 pgi 5.3.1.9 G Belongs to the GPI family
OPEFLCOJ_00084 6.7e-34 yuzA S Domain of unknown function (DUF378)
OPEFLCOJ_00085 1.2e-85 K Bacterial transcription activator, effector binding domain
OPEFLCOJ_00088 2.7e-64 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
OPEFLCOJ_00089 3.4e-29 K Helix-turn-helix XRE-family like proteins
OPEFLCOJ_00090 2.5e-197 namA C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
OPEFLCOJ_00091 4.7e-165 S reductase
OPEFLCOJ_00092 1.9e-158 dkgB S Aldo/keto reductase family
OPEFLCOJ_00093 2.4e-239 S protein conserved in bacteria
OPEFLCOJ_00095 2.1e-111 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OPEFLCOJ_00096 9.9e-67 kapB G Kinase associated protein B
OPEFLCOJ_00097 2.1e-13 S double-stranded DNA endodeoxyribonuclease activity
OPEFLCOJ_00098 3.5e-12 S transposase or invertase
OPEFLCOJ_00099 2.3e-259 L Transposase
OPEFLCOJ_00100 9.3e-127 S transposase or invertase
OPEFLCOJ_00101 4.5e-190 yuxJ EGP Major facilitator Superfamily
OPEFLCOJ_00102 2.7e-64 ydiI Q protein, possibly involved in aromatic compounds catabolism
OPEFLCOJ_00103 6.5e-60 yuzC
OPEFLCOJ_00104 2e-212 L Transposase
OPEFLCOJ_00106 1.5e-184 E Spore germination protein
OPEFLCOJ_00107 1.9e-220 gerKC S spore germination
OPEFLCOJ_00108 1.7e-280 gerKA EG Spore germination protein
OPEFLCOJ_00110 3.3e-299 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OPEFLCOJ_00111 6.4e-108 yuiC S protein conserved in bacteria
OPEFLCOJ_00112 9.5e-47 yuiB S Putative membrane protein
OPEFLCOJ_00113 1.5e-230 yumB 1.6.99.3 C NADH dehydrogenase
OPEFLCOJ_00114 1.2e-185 yumC 1.18.1.2, 1.19.1.1 C reductase
OPEFLCOJ_00115 3.6e-94 S response to antibiotic
OPEFLCOJ_00116 8.4e-77 tcaA S response to antibiotic
OPEFLCOJ_00117 1.1e-55 ycdA S Domain of unknown function (DUF4352)
OPEFLCOJ_00118 2.2e-63 erpA S Belongs to the HesB IscA family
OPEFLCOJ_00119 5.6e-61 yuzD S protein conserved in bacteria
OPEFLCOJ_00120 5.1e-37 nifU O COG0694 Thioredoxin-like proteins and domains
OPEFLCOJ_00121 1.8e-200 yutH S Spore coat protein
OPEFLCOJ_00122 5.6e-86 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
OPEFLCOJ_00123 1.9e-138 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
OPEFLCOJ_00124 1.9e-74 yutE S Protein of unknown function DUF86
OPEFLCOJ_00125 3.4e-48 yutD S protein conserved in bacteria
OPEFLCOJ_00126 2.5e-172 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OPEFLCOJ_00127 1.9e-194 lytH M Peptidase, M23
OPEFLCOJ_00128 1.7e-120 yunB S Sporulation protein YunB (Spo_YunB)
OPEFLCOJ_00129 8.2e-48 yunC S Domain of unknown function (DUF1805)
OPEFLCOJ_00130 5.1e-286 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
OPEFLCOJ_00131 2.9e-273 sufB O FeS cluster assembly
OPEFLCOJ_00132 6.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
OPEFLCOJ_00133 9.1e-239 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OPEFLCOJ_00134 1.4e-242 sufD O assembly protein SufD
OPEFLCOJ_00135 2.7e-143 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
OPEFLCOJ_00137 1.6e-51 traF CO Thioredoxin
OPEFLCOJ_00138 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
OPEFLCOJ_00139 1.3e-63 arsC 1.20.4.1 P Belongs to the ArsC family
OPEFLCOJ_00140 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
OPEFLCOJ_00141 1.4e-215 fadA 2.3.1.16 I Belongs to the thiolase family
OPEFLCOJ_00142 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
OPEFLCOJ_00143 2.6e-14 S YuzL-like protein
OPEFLCOJ_00144 7.4e-42
OPEFLCOJ_00145 1.6e-55 yusN M Coat F domain
OPEFLCOJ_00146 8.1e-205 rodA D Belongs to the SEDS family
OPEFLCOJ_00147 3.3e-55 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
OPEFLCOJ_00148 5.1e-281 cls2 I PLD-like domain
OPEFLCOJ_00150 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OPEFLCOJ_00151 8.8e-270 L RNA-directed DNA polymerase (reverse transcriptase)
OPEFLCOJ_00152 1.2e-194 M1-600 T Putative diguanylate phosphodiesterase
OPEFLCOJ_00153 2e-301 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
OPEFLCOJ_00154 1.6e-105 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
OPEFLCOJ_00155 1.3e-142 pgdA 3.5.1.104, 3.5.1.41 G Polysaccharide deacetylase
OPEFLCOJ_00156 5.2e-245 ugtP 2.4.1.315 GT28 M Monogalactosyldiacylglycerol (MGDG) synthase
OPEFLCOJ_00157 1.5e-131
OPEFLCOJ_00158 6.7e-87 S Putative zinc-finger
OPEFLCOJ_00159 5e-93 K Belongs to the sigma-70 factor family. ECF subfamily
OPEFLCOJ_00160 2.1e-224 ykoN 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
OPEFLCOJ_00161 0.0 M Dolichyl-phosphate-mannose-protein mannosyltransferase
OPEFLCOJ_00162 2.9e-260 NU cell adhesion
OPEFLCOJ_00163 1.4e-189 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OPEFLCOJ_00164 5.8e-180 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
OPEFLCOJ_00165 1e-46 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
OPEFLCOJ_00166 2.1e-140 gntP EG GntP family permease
OPEFLCOJ_00167 9e-150 uxuA 4.2.1.8 H Catalyzes the dehydration of D-mannonate
OPEFLCOJ_00168 1.1e-178 mtlD 1.1.1.17, 1.1.1.57 G PFAM Mannitol dehydrogenase
OPEFLCOJ_00169 1.1e-286 uxaA 4.2.1.7, 4.4.1.24 G Altronate
OPEFLCOJ_00170 1.4e-278 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
OPEFLCOJ_00171 1.4e-192 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
OPEFLCOJ_00172 1.6e-120 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
OPEFLCOJ_00173 1.3e-137 K helix_turn_helix isocitrate lyase regulation
OPEFLCOJ_00174 1.6e-266 S PFAM Uncharacterised protein family UPF0236
OPEFLCOJ_00176 6e-219 O Peptidase S53
OPEFLCOJ_00177 5.2e-36 S Transcriptional Coactivator p15 (PC4)
OPEFLCOJ_00179 2.4e-27 sidE D nuclear chromosome segregation
OPEFLCOJ_00180 1.3e-37
OPEFLCOJ_00181 2.4e-36
OPEFLCOJ_00182 6.7e-98
OPEFLCOJ_00183 3.1e-151 S transposase or invertase
OPEFLCOJ_00185 5e-81 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OPEFLCOJ_00186 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
OPEFLCOJ_00187 9.7e-143 est 3.1.1.1 S Carboxylesterase
OPEFLCOJ_00188 2.5e-28 secG U Preprotein translocase subunit SecG
OPEFLCOJ_00189 7.1e-242 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
OPEFLCOJ_00190 1.9e-302 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
OPEFLCOJ_00191 6.9e-120 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
OPEFLCOJ_00192 2.2e-221 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
OPEFLCOJ_00193 9.6e-186 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
OPEFLCOJ_00194 1.2e-186 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
OPEFLCOJ_00195 8.7e-40 XAC3035 O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OPEFLCOJ_00196 5.4e-245 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
OPEFLCOJ_00198 1.3e-07 S Heavy-metal-associated domain
OPEFLCOJ_00199 7.4e-86 S Protein of unknown function (DUF1641)
OPEFLCOJ_00201 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
OPEFLCOJ_00202 1.3e-31
OPEFLCOJ_00204 1.1e-226 NT chemotaxis protein
OPEFLCOJ_00206 7.3e-20 S transposase or invertase
OPEFLCOJ_00207 5.4e-20 S transposase or invertase
OPEFLCOJ_00208 2e-158 S transposase or invertase
OPEFLCOJ_00209 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
OPEFLCOJ_00210 4.3e-86 uspF T Universal stress protein
OPEFLCOJ_00212 2.6e-191 ykfD E Belongs to the ABC transporter superfamily
OPEFLCOJ_00213 3.9e-178 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
OPEFLCOJ_00214 0.0 dppE E ABC transporter substrate-binding protein
OPEFLCOJ_00215 6.4e-190 dppD P Belongs to the ABC transporter superfamily
OPEFLCOJ_00216 1.4e-170 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OPEFLCOJ_00217 7.5e-161 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OPEFLCOJ_00218 6.2e-131 S Peptidase C26
OPEFLCOJ_00219 1.3e-184 corA P Mediates influx of magnesium ions
OPEFLCOJ_00220 8.8e-46 yhdB S YhdB-like protein
OPEFLCOJ_00222 5.1e-278 ycgB S Stage V sporulation protein R
OPEFLCOJ_00223 2.7e-185 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
OPEFLCOJ_00224 1.1e-135 3.2.1.18 GH33 E GDSL-like Lipase/Acylhydrolase
OPEFLCOJ_00225 3.1e-77 bdbC O Required for disulfide bond formation in some proteins
OPEFLCOJ_00226 1.4e-86 bdbA CO Thioredoxin
OPEFLCOJ_00227 4.9e-90 yhcU S Family of unknown function (DUF5365)
OPEFLCOJ_00228 3.3e-112 ykaA P Protein of unknown function DUF47
OPEFLCOJ_00229 3.9e-179 pit P phosphate transporter
OPEFLCOJ_00230 1.1e-103 2.3.1.128 J Acetyltransferase (GNAT) domain
OPEFLCOJ_00232 9.6e-222 yhbH S Belongs to the UPF0229 family
OPEFLCOJ_00233 0.0 prkA T Ser protein kinase
OPEFLCOJ_00234 2.6e-88 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
OPEFLCOJ_00235 2.1e-165 yhbB S Putative amidase domain
OPEFLCOJ_00236 2.1e-221 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OPEFLCOJ_00237 8.2e-103 yvbG U UPF0056 membrane protein
OPEFLCOJ_00238 6.6e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
OPEFLCOJ_00239 1.7e-84 S Rubrerythrin
OPEFLCOJ_00240 2.9e-167 pip 3.4.11.5, 3.5.1.101 S Releases the N-terminal proline from various substrates
OPEFLCOJ_00241 2.9e-145 tcyA ET Belongs to the bacterial solute-binding protein 3 family
OPEFLCOJ_00242 1.9e-116 tcyB P COG0765 ABC-type amino acid transport system, permease component
OPEFLCOJ_00243 4.5e-132 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OPEFLCOJ_00244 6e-149 focA P Formate/nitrite transporter
OPEFLCOJ_00245 5.5e-24
OPEFLCOJ_00246 9.9e-163 L DDE superfamily endonuclease
OPEFLCOJ_00248 3e-215 dhaT 1.1.1.1, 1.1.1.202 C alcohol dehydrogenase
OPEFLCOJ_00249 0.0 pflB 2.3.1.54 C formate acetyltransferase
OPEFLCOJ_00250 5.6e-143 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
OPEFLCOJ_00251 1.7e-99 1.5.1.38 S FMN reductase
OPEFLCOJ_00252 1.2e-89
OPEFLCOJ_00253 5.5e-170 bcrB S ABC transporter (permease)
OPEFLCOJ_00254 1.1e-169 bcrA V ABC transporter, ATP-binding protein
OPEFLCOJ_00255 9.5e-144 ypmR1 E G-D-S-L family
OPEFLCOJ_00256 6.2e-32
OPEFLCOJ_00258 5.8e-170 S High confidence in function and specificity
OPEFLCOJ_00259 1.8e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OPEFLCOJ_00260 2.2e-249 ykoH3 T Histidine kinase
OPEFLCOJ_00261 6e-109
OPEFLCOJ_00262 1.7e-64 folT 2.7.13.3 T ECF transporter, substrate-specific component
OPEFLCOJ_00263 5.1e-248 L PFAM Transposase, IS4-like
OPEFLCOJ_00264 3.4e-15 V AAA domain, putative AbiEii toxin, Type IV TA system
OPEFLCOJ_00265 6.9e-85 V AAA domain, putative AbiEii toxin, Type IV TA system
OPEFLCOJ_00266 5.1e-79 V Transport permease protein
OPEFLCOJ_00267 1.6e-149 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
OPEFLCOJ_00268 6e-58 K MarR family
OPEFLCOJ_00269 8.4e-238 L Transposase DDE domain group 1
OPEFLCOJ_00270 7e-78 S Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)
OPEFLCOJ_00271 7.4e-59 S Predicted membrane protein (DUF2243)
OPEFLCOJ_00272 1.7e-66 V ATPases associated with a variety of cellular activities
OPEFLCOJ_00273 5.5e-125
OPEFLCOJ_00274 1.6e-117 tetV EGP Transmembrane secretion effector
OPEFLCOJ_00275 6e-255 ydjE EGP Major facilitator superfamily
OPEFLCOJ_00276 1e-151 yxxF EG EamA-like transporter family
OPEFLCOJ_00277 1.3e-204 adhC 1.1.1.1 C Zinc-binding dehydrogenase
OPEFLCOJ_00279 6.5e-190 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OPEFLCOJ_00280 3.7e-76 yetF3 K membrane
OPEFLCOJ_00283 1.6e-08
OPEFLCOJ_00287 8.7e-08
OPEFLCOJ_00288 1.7e-07
OPEFLCOJ_00296 1.1e-40
OPEFLCOJ_00297 4.3e-42 S COG NOG14552 non supervised orthologous group
OPEFLCOJ_00298 3.8e-162 ygxA S Nucleotidyltransferase-like
OPEFLCOJ_00299 5e-57 ygzB S UPF0295 protein
OPEFLCOJ_00300 1.3e-139 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
OPEFLCOJ_00301 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
OPEFLCOJ_00302 3.1e-164 alsR K LysR substrate binding domain
OPEFLCOJ_00303 9.8e-82 perR P Belongs to the Fur family
OPEFLCOJ_00304 4.4e-100 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S Adenosyltransferase
OPEFLCOJ_00305 1.5e-65 P Ion transport
OPEFLCOJ_00306 2.5e-247 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
OPEFLCOJ_00307 9.2e-189 ssuA P ABC transporter substrate-binding protein
OPEFLCOJ_00308 2.8e-140 P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
OPEFLCOJ_00309 6.4e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
OPEFLCOJ_00310 1.7e-111 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
OPEFLCOJ_00311 5.2e-221 yitG EGP Major facilitator Superfamily
OPEFLCOJ_00313 2.4e-267 S PFAM Uncharacterised protein family UPF0236
OPEFLCOJ_00314 1.1e-45
OPEFLCOJ_00315 4.9e-39 yqhV S Protein of unknown function (DUF2619)
OPEFLCOJ_00316 2.2e-188 ygaE S Membrane
OPEFLCOJ_00317 2.9e-154 K transcriptional
OPEFLCOJ_00318 1.6e-253 sacX 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OPEFLCOJ_00319 1.9e-153 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
OPEFLCOJ_00320 5.1e-209 yleB 4.2.1.126 S Bacterial protein of unknown function (DUF871)
OPEFLCOJ_00321 0.0 ygaD V ABC transporter
OPEFLCOJ_00322 2.8e-104 ygaC J Belongs to the UPF0374 family
OPEFLCOJ_00323 6e-36 ygaB S YgaB-like protein
OPEFLCOJ_00324 5.7e-09 sspE S Small, acid-soluble spore protein, gamma-type
OPEFLCOJ_00325 7.7e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OPEFLCOJ_00326 3.8e-165 gltC K Transcriptional regulator
OPEFLCOJ_00327 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
OPEFLCOJ_00328 1.5e-288 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
OPEFLCOJ_00329 4.3e-52 S YfzA-like protein
OPEFLCOJ_00330 3.2e-99 S ABC-2 family transporter protein
OPEFLCOJ_00331 1.5e-158 V ABC transporter
OPEFLCOJ_00332 3.1e-22 sspK S reproduction
OPEFLCOJ_00333 1.7e-187 yfhP S membrane-bound metal-dependent
OPEFLCOJ_00334 1.3e-215 mutY L A G-specific
OPEFLCOJ_00335 8.3e-51 yfhH S Protein of unknown function (DUF1811)
OPEFLCOJ_00336 2.5e-144 recX 2.4.1.337 GT4 S Modulates RecA activity
OPEFLCOJ_00338 8.5e-24 yfhD S YfhD-like protein
OPEFLCOJ_00339 7.6e-146 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
OPEFLCOJ_00341 1.2e-227 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
OPEFLCOJ_00342 5e-257 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpC family
OPEFLCOJ_00343 1.9e-181 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OPEFLCOJ_00344 1.3e-108 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
OPEFLCOJ_00345 5.4e-264 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OPEFLCOJ_00346 6.8e-207 bacI V COG0577 ABC-type antimicrobial peptide transport system, permease component
OPEFLCOJ_00347 2.1e-120 V ATPases associated with a variety of cellular activities
OPEFLCOJ_00348 2e-186 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OPEFLCOJ_00350 1.1e-07
OPEFLCOJ_00351 5.9e-86 S Stage II sporulation protein M
OPEFLCOJ_00352 2e-126 V ABC transporter
OPEFLCOJ_00354 6.1e-44 S Bacteriocin class IId cyclical uberolysin-like
OPEFLCOJ_00356 4.9e-160 XK27_10205
OPEFLCOJ_00357 1.2e-88 XK27_10205
OPEFLCOJ_00358 2.6e-28 XK27_10205
OPEFLCOJ_00360 3.4e-61
OPEFLCOJ_00361 7e-127 V AAA domain, putative AbiEii toxin, Type IV TA system
OPEFLCOJ_00363 5.4e-113 K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OPEFLCOJ_00364 2.4e-267 comP 2.7.13.3 T Histidine kinase
OPEFLCOJ_00365 2.8e-129 comP 2.7.13.3 T Histidine kinase
OPEFLCOJ_00367 4e-164 comQ H Belongs to the FPP GGPP synthase family
OPEFLCOJ_00368 1.6e-126 ywdH 1.2.1.3, 1.2.1.71 C Belongs to the aldehyde dehydrogenase family
OPEFLCOJ_00369 1.4e-209 acrA1_1 Q Male sterility protein
OPEFLCOJ_00370 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
OPEFLCOJ_00372 2.6e-243 mcpA NT chemotaxis protein
OPEFLCOJ_00373 1.6e-182 serA1 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OPEFLCOJ_00374 1.1e-222 dhsS 1.12.1.2 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
OPEFLCOJ_00375 1.1e-300 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OPEFLCOJ_00376 5.9e-183 S Phosphotransferase system, EIIC
OPEFLCOJ_00377 1e-220 2.6.1.9 S HAD-hyrolase-like
OPEFLCOJ_00378 9.3e-192 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OPEFLCOJ_00379 1.6e-111 leuD 4.2.1.33, 4.2.1.35, 4.2.1.36 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OPEFLCOJ_00380 8.2e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OPEFLCOJ_00381 5.9e-205 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
OPEFLCOJ_00382 3e-287 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OPEFLCOJ_00383 3.6e-196 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OPEFLCOJ_00384 1.1e-84 ilvN 2.2.1.6 E Acetolactate synthase
OPEFLCOJ_00385 0.0 ilvB 2.2.1.6 E Acetolactate synthase
OPEFLCOJ_00386 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
OPEFLCOJ_00387 2.7e-244 braB E Component of the transport system for branched-chain amino acids
OPEFLCOJ_00388 1.7e-151 T STAS domain
OPEFLCOJ_00389 8.7e-245
OPEFLCOJ_00390 1.1e-252 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
OPEFLCOJ_00391 1.2e-104 yetJ S Belongs to the BI1 family
OPEFLCOJ_00392 3.5e-230 L PFAM Transposase, IS116 IS110 IS902
OPEFLCOJ_00393 7.4e-191 yxjG 2.1.1.14 E Methionine synthase
OPEFLCOJ_00394 3e-248 L PFAM Transposase, IS4-like
OPEFLCOJ_00395 1.6e-219 yhjX P Major facilitator superfamily
OPEFLCOJ_00396 3.6e-137 ypdB T LytTr DNA-binding domain
OPEFLCOJ_00397 0.0 ypdA 2.7.13.3 T Signal transduction histidine kinase
OPEFLCOJ_00398 1.4e-197 ansA 3.5.1.1 EJ L-asparaginase
OPEFLCOJ_00399 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
OPEFLCOJ_00400 7.4e-106 yhgD K Transcriptional regulator
OPEFLCOJ_00401 6.9e-277 yhgE S YhgE Pip N-terminal domain protein
OPEFLCOJ_00402 2e-264 S Protein of unknown function (DUF2397)
OPEFLCOJ_00403 5.6e-230 S Protein of unknown function (DUF2398)
OPEFLCOJ_00404 0.0 D Putative exonuclease SbcCD, C subunit
OPEFLCOJ_00405 2e-252 S Protein of unknown function N-terminus (DUF3323)
OPEFLCOJ_00406 3.8e-87
OPEFLCOJ_00408 3.8e-195 NT chemotaxis protein
OPEFLCOJ_00409 7.9e-157 yoaT S Protein of unknown function (DUF817)
OPEFLCOJ_00410 1.2e-29 yozG K Transcriptional regulator
OPEFLCOJ_00411 6.6e-76 yoaS S Protein of unknown function (DUF2975)
OPEFLCOJ_00412 1.1e-54
OPEFLCOJ_00413 5.6e-237 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OPEFLCOJ_00414 2.8e-74 yqgC S protein conserved in bacteria
OPEFLCOJ_00415 8.8e-265 ydbT S Bacterial PH domain
OPEFLCOJ_00416 7.7e-88 S Bacterial PH domain
OPEFLCOJ_00417 7.9e-88 S AAA domain
OPEFLCOJ_00418 1.5e-32 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
OPEFLCOJ_00419 5.2e-262 proP EGP Transporter
OPEFLCOJ_00420 6.7e-192 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OPEFLCOJ_00421 5.3e-50 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OPEFLCOJ_00422 1.2e-143 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
OPEFLCOJ_00423 1.3e-126 NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
OPEFLCOJ_00424 2.3e-187 2.3.1.180 I 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III
OPEFLCOJ_00425 2.7e-58
OPEFLCOJ_00427 2.5e-250 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
OPEFLCOJ_00429 1.5e-306 lmrA 3.6.3.44 V ABC transporter
OPEFLCOJ_00430 1.6e-100 K Iron dependent repressor, N-terminal DNA binding domain
OPEFLCOJ_00431 4.9e-41
OPEFLCOJ_00432 1.2e-260 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OPEFLCOJ_00433 7.5e-155 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OPEFLCOJ_00434 9e-147 pdaA G deacetylase
OPEFLCOJ_00435 1.5e-26 yfjT
OPEFLCOJ_00436 9e-147 yfkD S YfkD-like protein
OPEFLCOJ_00437 3.4e-173 cax P COG0387 Ca2 H antiporter
OPEFLCOJ_00438 4.5e-219 yfkF EGP Major facilitator Superfamily
OPEFLCOJ_00439 7.3e-147 yihY S Belongs to the UPF0761 family
OPEFLCOJ_00440 7.3e-33 yfkK S Belongs to the UPF0435 family
OPEFLCOJ_00441 2.2e-142 map 3.4.11.18 E Methionine aminopeptidase
OPEFLCOJ_00442 9.2e-92 yfkM 3.5.1.124 S protease
OPEFLCOJ_00443 3.2e-123 motB N Flagellar motor protein
OPEFLCOJ_00444 2.8e-135 motA N flagellar motor
OPEFLCOJ_00445 1.3e-57 yhdN S Domain of unknown function (DUF1992)
OPEFLCOJ_00447 4.1e-59 yeaO S Protein of unknown function, DUF488
OPEFLCOJ_00448 2.9e-224 EGP Major facilitator Superfamily
OPEFLCOJ_00449 1.4e-144 dksA T COG1734 DnaK suppressor protein
OPEFLCOJ_00450 3.7e-85 ykhA 3.1.2.20 I Acyl-CoA hydrolase
OPEFLCOJ_00451 2.2e-182 mreB D Rod-share determining protein MreBH
OPEFLCOJ_00452 2.7e-168 yuaG S protein conserved in bacteria
OPEFLCOJ_00453 8.8e-88 yuaF OU Membrane protein implicated in regulation of membrane protease activity
OPEFLCOJ_00454 3e-212 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
OPEFLCOJ_00455 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
OPEFLCOJ_00456 2.1e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
OPEFLCOJ_00457 4.2e-118 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
OPEFLCOJ_00458 4.8e-102 4.2.1.1 P Reversible hydration of carbon dioxide
OPEFLCOJ_00460 3.1e-127 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OPEFLCOJ_00462 7e-297 K helix_turn_helix, Lux Regulon
OPEFLCOJ_00463 3.7e-108 che
OPEFLCOJ_00464 3.4e-68 S response to pH
OPEFLCOJ_00465 1.2e-96
OPEFLCOJ_00466 9.4e-140 ypuA S Secreted protein
OPEFLCOJ_00467 1.6e-216 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
OPEFLCOJ_00468 4.2e-218 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OPEFLCOJ_00469 1.5e-109 cobC 3.1.3.3, 3.1.3.73, 5.4.2.12 G Histidine phosphatase superfamily (branch 1)
OPEFLCOJ_00470 8e-70 K Transcriptional
OPEFLCOJ_00471 1.6e-266 S PFAM Uncharacterised protein family UPF0236
OPEFLCOJ_00472 4.4e-39 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
OPEFLCOJ_00473 4.9e-161 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
OPEFLCOJ_00474 1.3e-98 cas4 3.1.12.1 L RecB family exonuclease
OPEFLCOJ_00475 1.2e-133 csd2 L CRISPR-associated protein
OPEFLCOJ_00476 1.1e-270 csd1 3.5.1.28 M CRISPR-associated protein (Cas_Csd1)
OPEFLCOJ_00477 1.2e-116 cas5d S CRISPR-associated protein (Cas_Cas5)
OPEFLCOJ_00478 0.0 cas3 L Metal dependent phosphohydrolases with conserved 'HD' motif.
OPEFLCOJ_00480 0.0 snf 2.7.11.1 L COG0553 Superfamily II DNA RNA helicases, SNF2 family
OPEFLCOJ_00481 2.7e-108 C Nitroreductase family
OPEFLCOJ_00482 9.1e-89 1.8.5.2 S DoxX
OPEFLCOJ_00483 2e-191 fni 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
OPEFLCOJ_00484 2.5e-118 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
OPEFLCOJ_00485 6e-35 yoeD G Helix-turn-helix domain
OPEFLCOJ_00486 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
OPEFLCOJ_00487 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
OPEFLCOJ_00488 8.4e-134 fruR K Transcriptional regulator
OPEFLCOJ_00489 1.2e-202 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
OPEFLCOJ_00490 1.6e-94 D Hemerythrin HHE cation binding
OPEFLCOJ_00491 1.1e-152 yidA S hydrolases of the HAD superfamily
OPEFLCOJ_00492 3.5e-57 ygbA S Nitrous oxide-stimulated promoter
OPEFLCOJ_00493 1.7e-84 G phosphoenolpyruvate-dependent sugar phosphotransferase system
OPEFLCOJ_00494 7e-273 iolT EGP Major facilitator Superfamily
OPEFLCOJ_00495 2.8e-204 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
OPEFLCOJ_00497 6.2e-73 ywnF S Family of unknown function (DUF5392)
OPEFLCOJ_00498 2.4e-136 ywaC 2.7.6.5 S protein conserved in bacteria
OPEFLCOJ_00499 4.5e-255 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OPEFLCOJ_00500 2.3e-192 yhdN C Aldo keto reductase
OPEFLCOJ_00502 2e-59 dhaM 2.7.1.121 S PTS system fructose IIA component
OPEFLCOJ_00503 3.3e-101 dhaL 2.7.1.121 S Dak2
OPEFLCOJ_00504 1.4e-181 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase DhaK, subunit
OPEFLCOJ_00505 1.3e-174 pfoS S Phosphotransferase system, EIIC
OPEFLCOJ_00506 6.8e-119 ureH S PFAM Nickel cobalt transporter, high-affinity
OPEFLCOJ_00507 3.1e-158 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
OPEFLCOJ_00508 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
OPEFLCOJ_00509 1.7e-125 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
OPEFLCOJ_00510 6e-79 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
OPEFLCOJ_00511 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
OPEFLCOJ_00512 2.4e-53 ureB 3.5.1.5 E Belongs to the urease beta subunit family
OPEFLCOJ_00513 3.7e-48 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
OPEFLCOJ_00514 5.5e-202 amiF 3.5.1.49 S Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide
OPEFLCOJ_00515 0.0 F COG1457 Purine-cytosine permease and related proteins
OPEFLCOJ_00516 1.5e-196 amiE 3.5.1.4 S Carbon-nitrogen hydrolase
OPEFLCOJ_00517 0.0 KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
OPEFLCOJ_00518 1.4e-136 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
OPEFLCOJ_00519 2.4e-240 E COG1113 Gamma-aminobutyrate permease and related permeases
OPEFLCOJ_00520 6.5e-168 ytnM S membrane transporter protein
OPEFLCOJ_00522 4.5e-228 ywdJ F Xanthine uracil
OPEFLCOJ_00523 0.0 yjcD 3.6.4.12 L DNA helicase
OPEFLCOJ_00524 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OPEFLCOJ_00525 3e-248 L PFAM Transposase, IS4-like
OPEFLCOJ_00526 3e-248 L PFAM Transposase, IS4-like
OPEFLCOJ_00528 9.4e-98 O HI0933-like protein
OPEFLCOJ_00531 4.1e-80 K Acetyltransferase (GNAT) domain
OPEFLCOJ_00532 6.7e-292 yngE I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
OPEFLCOJ_00533 3.5e-135 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
OPEFLCOJ_00534 6.2e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
OPEFLCOJ_00535 4.8e-15 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
OPEFLCOJ_00536 1.1e-253 yngH 6.3.4.14, 6.3.4.6, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
OPEFLCOJ_00537 7.7e-216 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
OPEFLCOJ_00538 0.0 6.2.1.1 I AMP-dependent synthetase
OPEFLCOJ_00539 6.6e-295 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OPEFLCOJ_00540 2.1e-247 zraR KT Transcriptional regulator
OPEFLCOJ_00541 2.4e-231 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
OPEFLCOJ_00542 1.1e-242 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
OPEFLCOJ_00543 5.3e-67 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
OPEFLCOJ_00544 9.5e-272 hsdM 2.1.1.72 V Type I restriction-modification system
OPEFLCOJ_00545 2.1e-94 K -acetyltransferase
OPEFLCOJ_00547 0.0 hsdR 3.1.21.3 L COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
OPEFLCOJ_00548 1.6e-274 lysP E amino acid
OPEFLCOJ_00549 2e-107 K Transcriptional regulator
OPEFLCOJ_00550 2e-201 ybhR V COG0842 ABC-type multidrug transport system, permease component
OPEFLCOJ_00551 6.6e-128 V COG1131 ABC-type multidrug transport system, ATPase component
OPEFLCOJ_00552 8e-70 S Hemerythrin HHE cation binding domain
OPEFLCOJ_00553 9.3e-52
OPEFLCOJ_00554 3.5e-42
OPEFLCOJ_00555 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OPEFLCOJ_00556 7.8e-309 narH 1.7.5.1 C Nitrate reductase, beta
OPEFLCOJ_00557 7.9e-100 narJ C nitrate reductase molybdenum cofactor assembly chaperone
OPEFLCOJ_00558 1.6e-126 narI 1.7.5.1 C nitrate reductase, gamma subunit
OPEFLCOJ_00559 6.2e-205 narT P COG2223 Nitrate nitrite transporter
OPEFLCOJ_00560 1.5e-161 fda 4.1.2.13 G Belongs to the class I fructose-bisphosphate aldolase family
OPEFLCOJ_00561 3.6e-44 M SIS domain
OPEFLCOJ_00562 7.9e-80 S LXG domain of WXG superfamily
OPEFLCOJ_00563 5.8e-97 yokK S SMI1-KNR4 cell-wall
OPEFLCOJ_00564 5.5e-57 S Protein of unknown function, DUF600
OPEFLCOJ_00566 2e-197 mcrC V McrBC 5-methylcytosine restriction system component
OPEFLCOJ_00567 0.0 mcrB V AAA domain (dynein-related subfamily)
OPEFLCOJ_00568 0.0 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
OPEFLCOJ_00569 3.9e-85 hsdS_1 3.1.21.3 V Type I restriction modification DNA specificity domain
OPEFLCOJ_00570 0.0 hsdM 2.1.1.72 V Type I restriction-modification system
OPEFLCOJ_00571 9.4e-39 S Protein of unknown function, DUF600
OPEFLCOJ_00572 3.5e-36 yxiG
OPEFLCOJ_00573 1.5e-36 S Protein of unknown function, DUF600
OPEFLCOJ_00574 5.5e-16
OPEFLCOJ_00576 1.5e-26
OPEFLCOJ_00577 3.2e-137 cysK 2.5.1.47 E Pyridoxal-phosphate dependent enzyme
OPEFLCOJ_00578 1.1e-92 ytlI K Bacterial regulatory helix-turn-helix protein, lysR family
OPEFLCOJ_00579 4.1e-37 ssuE 1.5.1.38 S FMN reductase
OPEFLCOJ_00580 6.2e-57 ytmI K Acetyltransferase (GNAT) domain
OPEFLCOJ_00581 3.3e-104 ytmJ ET Bacterial periplasmic substrate-binding proteins
OPEFLCOJ_00582 1.3e-100 tcyK ET L-cystine-binding protein
OPEFLCOJ_00583 9.8e-92 tcyL P permease
OPEFLCOJ_00584 2.3e-69 tcyM U Binding-protein-dependent transport system inner membrane component
OPEFLCOJ_00585 1.4e-96 tcyN 3.6.3.21 E amino acid
OPEFLCOJ_00586 2.5e-88 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OPEFLCOJ_00587 1.3e-23 ytnI O Glutaredoxin-like domain (DUF836)
OPEFLCOJ_00588 8.8e-187 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OPEFLCOJ_00589 4.1e-113 E LysE type translocator
OPEFLCOJ_00590 4.2e-83 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
OPEFLCOJ_00591 2.9e-79 2.7.1.199 G COG2190 Phosphotransferase system IIA components
OPEFLCOJ_00592 5.7e-255 3.2.1.122, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
OPEFLCOJ_00593 1.7e-285 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OPEFLCOJ_00594 2.3e-128 K Helix-turn-helix domain, rpiR family
OPEFLCOJ_00595 1e-144 mleP S Membrane transport protein
OPEFLCOJ_00596 1.4e-255 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme, NAD binding domain
OPEFLCOJ_00597 2.7e-147 mleR K LysR substrate binding domain
OPEFLCOJ_00598 3.7e-118 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OPEFLCOJ_00600 3.8e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OPEFLCOJ_00601 2.2e-84 nrdG 1.97.1.4 O 4Fe-4S single cluster domain
OPEFLCOJ_00602 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
OPEFLCOJ_00603 5.4e-195 U protein localization to endoplasmic reticulum
OPEFLCOJ_00604 4.3e-189 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
OPEFLCOJ_00605 2.9e-73 KT Sugar diacid utilization regulator
OPEFLCOJ_00606 1.6e-191 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
OPEFLCOJ_00607 3.3e-162 EG Gluconate proton symporter
OPEFLCOJ_00609 2.9e-157 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
OPEFLCOJ_00610 8.8e-149 rbsC G Belongs to the binding-protein-dependent transport system permease family
OPEFLCOJ_00611 1.2e-280 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
OPEFLCOJ_00612 3.2e-68 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
OPEFLCOJ_00613 1.7e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OPEFLCOJ_00614 9.3e-178 rbsR K transcriptional
OPEFLCOJ_00616 1.7e-12 S transposase or invertase
OPEFLCOJ_00618 1.4e-159 S transposase or invertase
OPEFLCOJ_00619 9e-89 1.4.3.5 S Pyridoxamine 5'phosphate oxidase-like, FMN-binding
OPEFLCOJ_00620 7.2e-08 S transposase or invertase
OPEFLCOJ_00621 3.3e-145 S transposase or invertase
OPEFLCOJ_00622 3.7e-108 ycnI S Domain of unkown function (DUF1775)
OPEFLCOJ_00623 8.3e-304 ycnJ P protein, homolog of Cu resistance protein CopC
OPEFLCOJ_00624 2.3e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OPEFLCOJ_00625 6.7e-130 5.1.3.1 G Ribulose-phosphate 3 epimerase family
OPEFLCOJ_00626 1.1e-178 rbsR K transcriptional
OPEFLCOJ_00627 1.8e-257 G PTS system sugar-specific permease component
OPEFLCOJ_00628 1.7e-51
OPEFLCOJ_00629 3.5e-09 2.7.13.3 T His Kinase A (phosphoacceptor) domain
OPEFLCOJ_00630 1.1e-232 2.7.13.3 T His Kinase A (phosphoacceptor) domain
OPEFLCOJ_00631 1.2e-216 2.3.1.179 IQ Beta-ketoacyl synthase, C-terminal domain
OPEFLCOJ_00632 1.3e-28 cspL K Cold shock
OPEFLCOJ_00633 3.6e-178 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OPEFLCOJ_00634 1.9e-91 ydfC EG EamA-like transporter family
OPEFLCOJ_00636 1.2e-145 G Major Facilitator Superfamily
OPEFLCOJ_00638 1.4e-162 ydcZ S Putative inner membrane exporter, YdcZ
OPEFLCOJ_00639 0.0 nagA 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
OPEFLCOJ_00640 0.0 ampC V Belongs to the UPF0214 family
OPEFLCOJ_00641 8.9e-60 ybbC 3.2.1.52 S protein conserved in bacteria
OPEFLCOJ_00642 4.6e-165 ybbC 3.2.1.52 S protein conserved in bacteria
OPEFLCOJ_00644 3.1e-74
OPEFLCOJ_00645 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
OPEFLCOJ_00646 0.0 yfiB V ABC transporter
OPEFLCOJ_00647 4.7e-79 K helix_turn_helix multiple antibiotic resistance protein
OPEFLCOJ_00648 3.2e-109 3.1.3.18 S Haloacid dehalogenase-like hydrolase
OPEFLCOJ_00649 1.4e-245 L PFAM Transposase, IS4-like
OPEFLCOJ_00650 1e-105 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
OPEFLCOJ_00651 1.5e-60 QT Purine catabolism regulatory protein-like family
OPEFLCOJ_00652 7.1e-84 QT Purine catabolism regulatory protein-like family
OPEFLCOJ_00653 8.4e-113 S Protein of unknown function (DUF3237)
OPEFLCOJ_00654 8e-282 estC CE10 I Belongs to the type-B carboxylesterase lipase family
OPEFLCOJ_00655 7.2e-275 3.5.1.4 J Belongs to the amidase family
OPEFLCOJ_00656 6.9e-181 EGP Major facilitator Superfamily
OPEFLCOJ_00657 5.6e-39 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C belongs to the aldehyde dehydrogenase family
OPEFLCOJ_00658 8.7e-111 P Integral membrane protein TerC family
OPEFLCOJ_00659 2.7e-67
OPEFLCOJ_00661 3.9e-146 XK27_04815 S Membrane transport protein
OPEFLCOJ_00662 0.0
OPEFLCOJ_00663 0.0 V COG1401 GTPase subunit of restriction endonuclease
OPEFLCOJ_00664 3.9e-145
OPEFLCOJ_00665 2.2e-306 yhcX K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
OPEFLCOJ_00666 6.4e-24 S Uncharacterized small protein (DUF2292)
OPEFLCOJ_00667 1.4e-95 ssuE 1.5.1.38 S FMN reductase
OPEFLCOJ_00668 5.1e-139 ssuB P Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
OPEFLCOJ_00669 6.6e-123 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
OPEFLCOJ_00670 2e-216 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
OPEFLCOJ_00671 6.1e-169 P ABC transporter substrate-binding protein
OPEFLCOJ_00672 1e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
OPEFLCOJ_00674 5.8e-85 S SMI1-KNR4 cell-wall
OPEFLCOJ_00675 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OPEFLCOJ_00676 2e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
OPEFLCOJ_00677 1.3e-111 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OPEFLCOJ_00678 1.1e-234 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
OPEFLCOJ_00679 5.2e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
OPEFLCOJ_00681 6.7e-173 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
OPEFLCOJ_00682 1.8e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
OPEFLCOJ_00683 6.4e-213 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OPEFLCOJ_00684 8.6e-219 pbuO_1 S permease
OPEFLCOJ_00685 8.8e-116 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
OPEFLCOJ_00686 8e-166 S Protein of unknown function (DUF979)
OPEFLCOJ_00687 6.5e-117 S Protein of unknown function (DUF969)
OPEFLCOJ_00688 2.6e-135 ycsF S Belongs to the UPF0271 (lamB) family
OPEFLCOJ_00689 1.2e-180 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
OPEFLCOJ_00690 1e-133 kipI 3.5.1.54, 6.3.4.6 E Allophanate hydrolase subunit 1
OPEFLCOJ_00691 1.2e-214 EGP Major facilitator Superfamily
OPEFLCOJ_00692 1.3e-78 ymaD O redox protein, regulator of disulfide bond formation
OPEFLCOJ_00693 2.7e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OPEFLCOJ_00694 7.6e-115 artQ E COG0765 ABC-type amino acid transport system, permease component
OPEFLCOJ_00695 2e-135 artP ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
OPEFLCOJ_00696 2.6e-219 hipO3 3.5.1.47 S amidohydrolase
OPEFLCOJ_00697 0.0 htpG O Molecular chaperone. Has ATPase activity
OPEFLCOJ_00698 4.8e-207 M FFAT motif binding
OPEFLCOJ_00699 2.8e-57 I Domain of unknown function (DUF4430)
OPEFLCOJ_00700 3.7e-94 S Psort location CytoplasmicMembrane, score
OPEFLCOJ_00701 3e-248 L PFAM Transposase, IS4-like
OPEFLCOJ_00703 1.4e-107 crtF 2.1.1.210, 2.1.1.281, 2.1.1.79 M Methyltransferase
OPEFLCOJ_00704 2.6e-208 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
OPEFLCOJ_00705 1.5e-32 S Protein of unknown function DUF86
OPEFLCOJ_00706 7.6e-40 S Nucleotidyltransferase domain
OPEFLCOJ_00707 5.3e-192 adhP 1.1.1.1 C alcohol dehydrogenase
OPEFLCOJ_00709 7.4e-85 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OPEFLCOJ_00710 2.7e-40 S Protein of unknown function (DUF2750)
OPEFLCOJ_00711 2.2e-24 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
OPEFLCOJ_00712 6.5e-112 EGP Major facilitator Superfamily
OPEFLCOJ_00713 8.5e-142 IQ Enoyl-(Acyl carrier protein) reductase
OPEFLCOJ_00714 1.8e-145 S Protein of unknown function
OPEFLCOJ_00717 5.6e-24 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
OPEFLCOJ_00718 2.3e-281 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
OPEFLCOJ_00719 3.7e-185
OPEFLCOJ_00720 4.1e-38 yxjI S LURP-one-related
OPEFLCOJ_00721 3.5e-17 yxjI S LURP-one-related
OPEFLCOJ_00722 0.0 L Domain of unknown function (DUF4277)
OPEFLCOJ_00723 1.2e-260 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OPEFLCOJ_00724 3.5e-230 L PFAM Transposase, IS116 IS110 IS902
OPEFLCOJ_00725 1.7e-268 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OPEFLCOJ_00726 4.2e-172 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
OPEFLCOJ_00728 1.7e-153 Q N-acetyltransferase
OPEFLCOJ_00731 3.9e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OPEFLCOJ_00732 8.5e-276 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
OPEFLCOJ_00733 1.5e-46 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OPEFLCOJ_00734 1.8e-245 aceA 4.1.3.1 C Isocitrate lyase
OPEFLCOJ_00735 0.0 aceB 2.3.3.9 C Belongs to the malate synthase family
OPEFLCOJ_00736 7.4e-222 camS S COG4851 Protein involved in sex pheromone biosynthesis
OPEFLCOJ_00737 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OPEFLCOJ_00738 6e-299 pcrA 3.6.4.12 L ATP-dependent DNA helicase
OPEFLCOJ_00739 4.5e-126 pcrA 3.6.4.12 L AAA domain
OPEFLCOJ_00740 1.4e-130 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
OPEFLCOJ_00741 1.2e-52 yerC S protein conserved in bacteria
OPEFLCOJ_00742 3.8e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
OPEFLCOJ_00743 0.0 yerA 3.5.4.2 F adenine deaminase
OPEFLCOJ_00744 5.5e-36 S Protein of unknown function (DUF2892)
OPEFLCOJ_00745 3.4e-225 purD 6.3.4.13 F Belongs to the GARS family
OPEFLCOJ_00746 4.2e-286 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
OPEFLCOJ_00747 3.2e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OPEFLCOJ_00748 1.3e-188 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
OPEFLCOJ_00749 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OPEFLCOJ_00750 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OPEFLCOJ_00751 6.8e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OPEFLCOJ_00752 9e-40 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OPEFLCOJ_00753 2.1e-126 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
OPEFLCOJ_00754 1.1e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OPEFLCOJ_00755 9.9e-219 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OPEFLCOJ_00756 1.1e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OPEFLCOJ_00757 5.4e-30 yebG S NETI protein
OPEFLCOJ_00758 3.1e-90 yebE S UPF0316 protein
OPEFLCOJ_00759 1.1e-116 frnE Q dithiol-disulfide isomerase involved in polyketide biosynthesis
OPEFLCOJ_00760 5.7e-43 nagE 2.7.1.193, 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
OPEFLCOJ_00762 2.9e-33 glvR K Helix-turn-helix domain, rpiR family
OPEFLCOJ_00763 4.1e-199 glvC 2.7.1.199, 2.7.1.208 G pts system
OPEFLCOJ_00764 6e-191 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
OPEFLCOJ_00765 1.7e-41
OPEFLCOJ_00766 4.3e-42 S COG NOG14552 non supervised orthologous group
OPEFLCOJ_00767 2.7e-222 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OPEFLCOJ_00768 0.0 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OPEFLCOJ_00769 2.3e-156 glcT K antiterminator
OPEFLCOJ_00770 2.3e-232 pbuG S permease
OPEFLCOJ_00772 0.0 ywjA V ABC transporter
OPEFLCOJ_00773 2.8e-216 ynfM EGP Major facilitator Superfamily
OPEFLCOJ_00774 5.6e-118 yfiK K Regulator
OPEFLCOJ_00775 1.9e-195 T Histidine kinase
OPEFLCOJ_00776 5.8e-169 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
OPEFLCOJ_00777 1.3e-199 yfiM V ABC-2 type transporter
OPEFLCOJ_00778 5e-207 yfiN V COG0842 ABC-type multidrug transport system, permease component
OPEFLCOJ_00779 2.6e-224 1.13.11.4 Q Cupin domain
OPEFLCOJ_00780 2.3e-87 S DinB superfamily
OPEFLCOJ_00781 1.8e-56 3.7.1.5 Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
OPEFLCOJ_00782 2e-101 3.7.1.5 Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
OPEFLCOJ_00783 1.3e-142 K helix_turn_helix isocitrate lyase regulation
OPEFLCOJ_00784 3.6e-102
OPEFLCOJ_00785 3e-54 1.14.13.127 CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OPEFLCOJ_00786 2.5e-88 1.14.13.127 CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OPEFLCOJ_00787 4.3e-76 ysmA 3.1.2.23 S Thioesterase-like superfamily
OPEFLCOJ_00788 7.2e-308 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OPEFLCOJ_00789 4.5e-219 bktB 2.3.1.16, 2.3.1.9 I Belongs to the thiolase family
OPEFLCOJ_00790 2.5e-141 4.2.1.17 I Enoyl-CoA hydratase/isomerase
OPEFLCOJ_00791 2.4e-156 hbd 1.1.1.157 I Dehydrogenase
OPEFLCOJ_00792 6.4e-32 cyaD 2.7.11.1, 3.1.4.52, 4.6.1.1 QT Domain present in phytochromes and cGMP-specific phosphodiesterases.
OPEFLCOJ_00793 5e-132 cyaD 2.7.11.1, 3.1.4.52, 4.6.1.1 QT Domain present in phytochromes and cGMP-specific phosphodiesterases.
OPEFLCOJ_00794 1.1e-216 benK EGP Major facilitator Superfamily
OPEFLCOJ_00795 3.9e-142 K helix_turn_helix isocitrate lyase regulation
OPEFLCOJ_00796 9.5e-163 3.7.1.20 Q Fumarylacetoacetate (FAA) hydrolase family
OPEFLCOJ_00797 4.5e-57 1.13.11.4 Q AraC-like ligand binding domain
OPEFLCOJ_00798 4e-139 1.13.11.4 Q AraC-like ligand binding domain
OPEFLCOJ_00799 9.9e-256 ybhI P Sodium:sulfate symporter transmembrane region
OPEFLCOJ_00800 1.3e-49 L deoxyribonuclease I activity
OPEFLCOJ_00801 0.0 XK27_11280 S Psort location CytoplasmicMembrane, score
OPEFLCOJ_00804 6.8e-129
OPEFLCOJ_00805 9.2e-127 yhcG V ABC transporter, ATP-binding protein
OPEFLCOJ_00806 1.6e-58 yhcF K Transcriptional regulator
OPEFLCOJ_00807 4.6e-97 padR K transcriptional
OPEFLCOJ_00808 5.1e-95 padC Q Phenolic acid decarboxylase
OPEFLCOJ_00809 7.4e-115 ywnB S NAD(P)H-binding
OPEFLCOJ_00810 1.4e-72 ywnA K Transcriptional regulator
OPEFLCOJ_00812 9e-181 L Mu transposase, C-terminal
OPEFLCOJ_00813 1.3e-63 L Mu transposase, C-terminal
OPEFLCOJ_00814 8.8e-150 U AAA domain
OPEFLCOJ_00815 2.1e-13 S transposase or invertase
OPEFLCOJ_00816 2.7e-158 S transposase or invertase
OPEFLCOJ_00817 6.9e-36 yeeD O Belongs to the sulfur carrier protein TusA family
OPEFLCOJ_00818 2.7e-191 yeeE S Sulphur transport
OPEFLCOJ_00819 2.5e-241 yihS 5.1.3.11, 5.3.1.9 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
OPEFLCOJ_00820 2.7e-171 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OPEFLCOJ_00821 1.7e-07
OPEFLCOJ_00822 6.3e-30 ybxH S Family of unknown function (DUF5370)
OPEFLCOJ_00823 1.9e-189 P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
OPEFLCOJ_00824 3.3e-138 fecE 3.6.3.34 HP ABC transporter
OPEFLCOJ_00825 9e-174 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OPEFLCOJ_00826 3.1e-93
OPEFLCOJ_00828 4.3e-147 emrB P Major facilitator superfamily
OPEFLCOJ_00829 8.8e-63 EGP Major facilitator Superfamily
OPEFLCOJ_00830 1.4e-27 K Helix-turn-helix domain
OPEFLCOJ_00831 4.7e-31
OPEFLCOJ_00832 2.7e-31 S Domain of unknown function (DUF4177)
OPEFLCOJ_00833 2.2e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
OPEFLCOJ_00834 1.4e-153 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
OPEFLCOJ_00835 5.5e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OPEFLCOJ_00836 8.9e-109 pncA Q COG1335 Amidases related to nicotinamidase
OPEFLCOJ_00837 4.7e-199 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
OPEFLCOJ_00838 0.0 ykoS
OPEFLCOJ_00839 4.3e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OPEFLCOJ_00840 2e-67 yngA S GtrA-like protein
OPEFLCOJ_00841 5.3e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
OPEFLCOJ_00842 9.7e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OPEFLCOJ_00843 8.1e-126 ydiL S CAAX protease self-immunity
OPEFLCOJ_00844 1.3e-27 S Domain of unknown function (DUF4305)
OPEFLCOJ_00845 5.1e-131 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OPEFLCOJ_00846 2.7e-123 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
OPEFLCOJ_00847 1.6e-08 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
OPEFLCOJ_00848 0.0 ydiF S ABC transporter
OPEFLCOJ_00849 8.9e-184 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OPEFLCOJ_00850 4.5e-82 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
OPEFLCOJ_00851 5.7e-129 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
OPEFLCOJ_00852 9e-83 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
OPEFLCOJ_00854 5.3e-43
OPEFLCOJ_00855 4.3e-42 S COG NOG14552 non supervised orthologous group
OPEFLCOJ_00860 1.6e-08
OPEFLCOJ_00868 1e-92 ydcK S Belongs to the SprT family
OPEFLCOJ_00869 0.0 yhgF K COG2183 Transcriptional accessory protein
OPEFLCOJ_00870 7.3e-109 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
OPEFLCOJ_00871 1.3e-137 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OPEFLCOJ_00872 2.3e-81 rsbW 2.7.11.1 T Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
OPEFLCOJ_00873 3.6e-61 rsbV T Belongs to the anti-sigma-factor antagonist family
OPEFLCOJ_00874 6.4e-190 rsbU 3.1.3.3 KT phosphatase
OPEFLCOJ_00875 2e-70 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
OPEFLCOJ_00876 2.1e-55 rsbS T antagonist
OPEFLCOJ_00877 3e-153 rsbR T Positive regulator of sigma-B
OPEFLCOJ_00878 7.2e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
OPEFLCOJ_00879 2e-40 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
OPEFLCOJ_00880 2.9e-218 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OPEFLCOJ_00881 8.4e-190 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
OPEFLCOJ_00882 1.2e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
OPEFLCOJ_00883 3.8e-105 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
OPEFLCOJ_00884 1.7e-260 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
OPEFLCOJ_00885 1.9e-130 E Amino acid permease
OPEFLCOJ_00886 2.7e-30
OPEFLCOJ_00887 3.4e-38
OPEFLCOJ_00888 3.8e-60
OPEFLCOJ_00889 3.2e-107 E Lysine exporter protein LysE YggA
OPEFLCOJ_00890 2.7e-123 otsB2 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
OPEFLCOJ_00891 2.9e-176 yvdE K Transcriptional regulator
OPEFLCOJ_00892 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
OPEFLCOJ_00893 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
OPEFLCOJ_00894 1.2e-241 mdxE G COG2182 Maltose-binding periplasmic proteins domains
OPEFLCOJ_00895 1.9e-242 malC P COG1175 ABC-type sugar transport systems, permease components
OPEFLCOJ_00896 3e-156 malD P transport
OPEFLCOJ_00897 7.3e-147 malA S Protein of unknown function (DUF1189)
OPEFLCOJ_00898 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
OPEFLCOJ_00899 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
OPEFLCOJ_00900 2.9e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
OPEFLCOJ_00901 4.8e-204 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
OPEFLCOJ_00902 2.1e-148
OPEFLCOJ_00903 2.7e-236 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
OPEFLCOJ_00904 7.8e-82 cueR K transcriptional
OPEFLCOJ_00905 1.7e-249 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
OPEFLCOJ_00907 1.4e-278 S PFAM Uncharacterised protein family UPF0236
OPEFLCOJ_00908 4.9e-309 ywqB S Zinc finger, swim domain protein
OPEFLCOJ_00909 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
OPEFLCOJ_00911 3.3e-71 ywpF S YwpF-like protein
OPEFLCOJ_00912 3.7e-63 ssbB L Single-stranded DNA-binding protein
OPEFLCOJ_00914 1.2e-73 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
OPEFLCOJ_00915 5e-148 flhP N flagellar basal body
OPEFLCOJ_00916 4.9e-145 flhO N flagellar basal body
OPEFLCOJ_00917 1e-179 mbl D Rod shape-determining protein
OPEFLCOJ_00918 1.3e-41 spoIIID K Stage III sporulation protein D
OPEFLCOJ_00919 4.1e-128 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
OPEFLCOJ_00920 3.4e-183 spoIID D Stage II sporulation protein D
OPEFLCOJ_00921 8.8e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OPEFLCOJ_00922 2.5e-135 ywmB S TATA-box binding
OPEFLCOJ_00923 1.4e-34 ywzB S membrane
OPEFLCOJ_00924 6.3e-59 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
OPEFLCOJ_00925 2.7e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OPEFLCOJ_00926 5e-151 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OPEFLCOJ_00927 3.4e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OPEFLCOJ_00928 2.9e-88 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OPEFLCOJ_00929 1e-37 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OPEFLCOJ_00930 1.3e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OPEFLCOJ_00931 8.2e-131 atpB C it plays a direct role in the translocation of protons across the membrane
OPEFLCOJ_00932 4.1e-57 atpI S ATP synthase I chain
OPEFLCOJ_00933 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OPEFLCOJ_00934 1.1e-239 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OPEFLCOJ_00935 6.1e-97 ywlG S Belongs to the UPF0340 family
OPEFLCOJ_00936 1.4e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
OPEFLCOJ_00937 8.8e-176 mcpA NT Chemotaxis
OPEFLCOJ_00938 2.4e-80 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OPEFLCOJ_00939 3.7e-91 mntP P Probably functions as a manganese efflux pump
OPEFLCOJ_00940 6.3e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
OPEFLCOJ_00941 7.4e-122 spoIIR S stage II sporulation protein R
OPEFLCOJ_00942 6.3e-162 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
OPEFLCOJ_00943 6.6e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OPEFLCOJ_00944 5.3e-07
OPEFLCOJ_00945 1.7e-110 tdk 2.7.1.21 F thymidine kinase
OPEFLCOJ_00946 2.2e-33 rpmE J Ribosomal protein L31
OPEFLCOJ_00947 2.7e-230 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OPEFLCOJ_00948 7.8e-177 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
OPEFLCOJ_00949 5.6e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OPEFLCOJ_00950 1.3e-114 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OPEFLCOJ_00951 3.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
OPEFLCOJ_00952 6e-61 spo0F T response regulator
OPEFLCOJ_00953 3e-248 L PFAM Transposase, IS4-like
OPEFLCOJ_00954 9.8e-219
OPEFLCOJ_00955 2.3e-148
OPEFLCOJ_00956 4.9e-125 yhcG V ABC transporter, ATP-binding protein
OPEFLCOJ_00957 2.7e-67 K helix_turn_helix gluconate operon transcriptional repressor
OPEFLCOJ_00958 2.2e-311 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
OPEFLCOJ_00959 2.7e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
OPEFLCOJ_00960 9.2e-124 V ATPases associated with a variety of cellular activities
OPEFLCOJ_00961 0.0 S FtsX-like permease family
OPEFLCOJ_00962 0.0 L Domain of unknown function (DUF4277)
OPEFLCOJ_00963 0.0 icmF 5.4.99.13 EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OPEFLCOJ_00964 5.2e-113 kstR2_2 K Transcriptional regulator
OPEFLCOJ_00965 1.8e-212 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
OPEFLCOJ_00966 3.7e-210 mmgC I acyl-CoA dehydrogenase
OPEFLCOJ_00967 9.4e-217 mmgA 2.3.1.9 I Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
OPEFLCOJ_00969 0.0 fadF C COG0247 Fe-S oxidoreductase
OPEFLCOJ_00970 4.4e-222 cls I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
OPEFLCOJ_00971 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
OPEFLCOJ_00972 5.7e-74 ywiB S Domain of unknown function (DUF1934)
OPEFLCOJ_00973 5.1e-167 speB 3.5.3.11 E Belongs to the arginase family
OPEFLCOJ_00974 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
OPEFLCOJ_00975 1.2e-91 ywhD S YwhD family
OPEFLCOJ_00976 7.3e-118 ywhC S Peptidase M50
OPEFLCOJ_00977 3.5e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
OPEFLCOJ_00978 2.3e-90 ywgA 2.1.1.72, 3.1.21.3
OPEFLCOJ_00979 3e-256 ywfO S COG1078 HD superfamily phosphohydrolases
OPEFLCOJ_00981 5.7e-100 rsfA S Transcriptional regulator
OPEFLCOJ_00982 1.7e-151 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
OPEFLCOJ_00983 3.5e-177 pta 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
OPEFLCOJ_00984 3.3e-146 ywfI C May function as heme-dependent peroxidase
OPEFLCOJ_00985 2.2e-81 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
OPEFLCOJ_00986 6.3e-58 ywdK S small membrane protein
OPEFLCOJ_00987 2.2e-38 S Family of unknown function (DUF5327)
OPEFLCOJ_00988 2.2e-133 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OPEFLCOJ_00989 3.6e-55 S Heat induced stress protein YflT
OPEFLCOJ_00991 3.5e-19 S Circ_ocin_uber circular bacteriocin, circularin A uberolysin family protein
OPEFLCOJ_00992 2.4e-243
OPEFLCOJ_00994 1.2e-261 L Transposase, IS4 family protein
OPEFLCOJ_00996 8.1e-208
OPEFLCOJ_00997 3e-248 L PFAM Transposase, IS4-like
OPEFLCOJ_00998 9.6e-152 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
OPEFLCOJ_00999 3.9e-62 yojF S Protein of unknown function (DUF1806)
OPEFLCOJ_01000 1.5e-129 bshB2 S deacetylase
OPEFLCOJ_01001 6.8e-164 ycsE S hydrolases of the HAD superfamily
OPEFLCOJ_01002 0.0 recQ 3.6.4.12 L DNA helicase
OPEFLCOJ_01003 3.4e-228 phoA 3.1.3.1 P Belongs to the alkaline phosphatase family
OPEFLCOJ_01004 1.5e-152 ybbH_2 K Transcriptional regulator
OPEFLCOJ_01005 1.1e-153 S Alpha/beta hydrolase of unknown function (DUF915)
OPEFLCOJ_01006 1.3e-13
OPEFLCOJ_01007 1.5e-75 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OPEFLCOJ_01009 2.2e-117 ywbG M effector of murein hydrolase
OPEFLCOJ_01010 3.7e-58 ywbH S LrgA family
OPEFLCOJ_01011 8.7e-181 ywbI K Transcriptional regulator
OPEFLCOJ_01012 0.0 asnO 6.3.5.4 E Asparagine synthase
OPEFLCOJ_01013 1.2e-127 S Protein of unknown function (DUF1646)
OPEFLCOJ_01015 6.7e-259 L Transposase
OPEFLCOJ_01016 8.8e-75 S Threonine/Serine exporter, ThrE
OPEFLCOJ_01017 1.9e-130 thrE S Putative threonine/serine exporter
OPEFLCOJ_01018 7.3e-208 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
OPEFLCOJ_01019 0.0 cstA T Carbon starvation protein
OPEFLCOJ_01020 1.4e-127 lytT T COG3279 Response regulator of the LytR AlgR family
OPEFLCOJ_01021 0.0 lytS 2.7.13.3 T Histidine kinase
OPEFLCOJ_01022 6e-141 metQ M Belongs to the nlpA lipoprotein family
OPEFLCOJ_01023 4.8e-101 metI P COG2011 ABC-type metal ion transport system, permease component
OPEFLCOJ_01024 1.4e-192 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OPEFLCOJ_01025 1.4e-144 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
OPEFLCOJ_01026 1.1e-101
OPEFLCOJ_01027 2.8e-221 pilM NU Pilus assembly protein
OPEFLCOJ_01028 3.6e-236 yisQ V Mate efflux family protein
OPEFLCOJ_01029 4.9e-153 M Glycosyl transferase family 8
OPEFLCOJ_01030 8.6e-237 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
OPEFLCOJ_01033 4.5e-272 EGP Major facilitator Superfamily
OPEFLCOJ_01034 3.2e-226 uraA F Xanthine uracil
OPEFLCOJ_01035 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
OPEFLCOJ_01036 1.3e-125 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OPEFLCOJ_01037 1.6e-300 msbA2 3.6.3.44 V ABC transporter
OPEFLCOJ_01038 7.1e-113 yhhQ_2 S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OPEFLCOJ_01039 2.2e-98 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OPEFLCOJ_01040 0.0 S MMPL domain protein
OPEFLCOJ_01041 2.4e-302 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
OPEFLCOJ_01042 5.7e-29 T diguanylate cyclase activity
OPEFLCOJ_01043 1.9e-135 gntR2 K UTRA
OPEFLCOJ_01044 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
OPEFLCOJ_01045 4.4e-149 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OPEFLCOJ_01046 6.3e-108 fliY ET Belongs to the bacterial solute-binding protein 3 family
OPEFLCOJ_01047 1.5e-91 artQ_1 E amino acid transport system, permease
OPEFLCOJ_01048 2.7e-105 glnQ2 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OPEFLCOJ_01049 2.9e-237 LYS1 1.5.1.7 E Saccharopine dehydrogenase
OPEFLCOJ_01050 4.5e-224 nspC 4.1.1.96 E Pyridoxal-dependent decarboxylase, C-terminal sheet domain
OPEFLCOJ_01051 1.1e-206 S Domain of unknown function (DUF1611_N) Rossmann-like domain
OPEFLCOJ_01052 1.8e-212 5.1.1.12 E Alanine racemase, N-terminal domain
OPEFLCOJ_01053 5.4e-142 cjaA ET Belongs to the bacterial solute-binding protein 3 family
OPEFLCOJ_01054 5.8e-132 glnQ 3.6.3.21 E ATPases associated with a variety of cellular activities
OPEFLCOJ_01055 2.6e-102 E amino acid ABC transporter
OPEFLCOJ_01056 4.4e-115 papP E amino acid ABC transporter
OPEFLCOJ_01057 1.3e-290 mqo 1.1.5.4 S malate quinone oxidoreductase
OPEFLCOJ_01058 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
OPEFLCOJ_01059 1.1e-93 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
OPEFLCOJ_01060 7.4e-299 hsdM 2.1.1.72 V Type I restriction-modification system
OPEFLCOJ_01061 4.9e-105
OPEFLCOJ_01062 9.5e-167 tnp L transposase activity
OPEFLCOJ_01063 6.2e-74 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OPEFLCOJ_01064 1.8e-181 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OPEFLCOJ_01065 8.5e-145 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
OPEFLCOJ_01066 1.7e-142 yycI S protein conserved in bacteria
OPEFLCOJ_01067 1.5e-247 yycH S protein conserved in bacteria
OPEFLCOJ_01068 0.0 vicK 2.7.13.3 T Histidine kinase
OPEFLCOJ_01069 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OPEFLCOJ_01072 1.2e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OPEFLCOJ_01073 3.7e-249 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
OPEFLCOJ_01074 1.2e-71 rplI J binds to the 23S rRNA
OPEFLCOJ_01075 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
OPEFLCOJ_01076 1.8e-146 yybS S membrane
OPEFLCOJ_01077 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OPEFLCOJ_01078 1.5e-86 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
OPEFLCOJ_01079 5e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
OPEFLCOJ_01080 7.4e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
OPEFLCOJ_01081 6.2e-224 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OPEFLCOJ_01082 2.6e-115 ribE 2.5.1.9 H Riboflavin synthase
OPEFLCOJ_01083 2.3e-209 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OPEFLCOJ_01084 5.9e-205 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
OPEFLCOJ_01085 1.1e-32 yyzM S protein conserved in bacteria
OPEFLCOJ_01086 1.1e-161 ykuT M Mechanosensitive ion channel
OPEFLCOJ_01087 3.3e-112 yyaC S Sporulation protein YyaC
OPEFLCOJ_01088 6.2e-118 ydfK S Protein of unknown function (DUF554)
OPEFLCOJ_01089 1.2e-149 spo0J K Belongs to the ParB family
OPEFLCOJ_01090 6.9e-136 soj D COG1192 ATPases involved in chromosome partitioning
OPEFLCOJ_01091 5.9e-152 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
OPEFLCOJ_01092 1.8e-133 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
OPEFLCOJ_01093 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
OPEFLCOJ_01094 5.8e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OPEFLCOJ_01095 8.2e-111 jag S single-stranded nucleic acid binding R3H
OPEFLCOJ_01096 1.4e-128 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
OPEFLCOJ_01097 1.4e-56 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
OPEFLCOJ_01098 2e-255 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OPEFLCOJ_01099 4.5e-208 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
OPEFLCOJ_01100 2.4e-33 yaaA S S4 domain
OPEFLCOJ_01101 2.3e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OPEFLCOJ_01102 9.6e-11 yaaB S Domain of unknown function (DUF370)
OPEFLCOJ_01103 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OPEFLCOJ_01104 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OPEFLCOJ_01105 8.9e-198 M1-161 T HD domain
OPEFLCOJ_01106 4.3e-42 S COG NOG14552 non supervised orthologous group
OPEFLCOJ_01109 1.7e-41
OPEFLCOJ_01110 3.9e-36 csfB S Inhibitor of sigma-G Gin
OPEFLCOJ_01111 1.8e-289 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
OPEFLCOJ_01112 2e-120 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OPEFLCOJ_01113 9.8e-55 yaaQ S protein conserved in bacteria
OPEFLCOJ_01114 1.8e-72 yaaR S protein conserved in bacteria
OPEFLCOJ_01115 4.3e-186 holB 2.7.7.7 L DNA polymerase III
OPEFLCOJ_01116 1.7e-148 yaaT S stage 0 sporulation protein
OPEFLCOJ_01117 4.5e-67 yabA L Involved in initiation control of chromosome replication
OPEFLCOJ_01118 2.2e-139 yabB 2.1.1.223 S Conserved hypothetical protein 95
OPEFLCOJ_01119 3.6e-48 yazA L endonuclease containing a URI domain
OPEFLCOJ_01120 1.8e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OPEFLCOJ_01121 1.2e-56 abrB K COG2002 Regulators of stationary sporulation gene expression
OPEFLCOJ_01122 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OPEFLCOJ_01123 3e-147 tatD L hydrolase, TatD
OPEFLCOJ_01124 8.5e-105 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OPEFLCOJ_01125 2.3e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
OPEFLCOJ_01126 8.7e-167 yabG S peptidase
OPEFLCOJ_01127 2.4e-37 veg S protein conserved in bacteria
OPEFLCOJ_01128 2.2e-34 sspF S DNA topological change
OPEFLCOJ_01129 3.2e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OPEFLCOJ_01130 2.9e-154 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
OPEFLCOJ_01131 3.2e-62 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
OPEFLCOJ_01132 3.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
OPEFLCOJ_01134 2.2e-75 S Psort location CytoplasmicMembrane, score
OPEFLCOJ_01135 6.3e-85 S Psort location CytoplasmicMembrane, score
OPEFLCOJ_01136 4.4e-93 V ABC transporter
OPEFLCOJ_01137 1e-81
OPEFLCOJ_01138 2.3e-246 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OPEFLCOJ_01139 3.6e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OPEFLCOJ_01140 2.4e-110 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OPEFLCOJ_01141 1.6e-102 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
OPEFLCOJ_01142 1.7e-37 yabK S Peptide ABC transporter permease
OPEFLCOJ_01143 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OPEFLCOJ_01144 6.2e-91 spoVT K stage V sporulation protein
OPEFLCOJ_01145 7.9e-291 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OPEFLCOJ_01146 1.1e-195 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
OPEFLCOJ_01147 1.1e-41 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
OPEFLCOJ_01148 4.7e-51 yabP S Sporulation protein YabP
OPEFLCOJ_01149 3.7e-111 yabQ S spore cortex biosynthesis protein
OPEFLCOJ_01150 5.5e-60 divIC D Septum formation initiator
OPEFLCOJ_01151 2.8e-54 yabR J RNA binding protein (contains ribosomal protein S1 domain)
OPEFLCOJ_01153 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
OPEFLCOJ_01154 4.3e-119 yabS S protein containing a von Willebrand factor type A (vWA) domain
OPEFLCOJ_01155 2e-167 KLT serine threonine protein kinase
OPEFLCOJ_01156 1.2e-277 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
OPEFLCOJ_01157 2.9e-96 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
OPEFLCOJ_01158 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OPEFLCOJ_01159 3.8e-142 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
OPEFLCOJ_01160 3e-159 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OPEFLCOJ_01161 8.9e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
OPEFLCOJ_01162 1.3e-159 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OPEFLCOJ_01163 4.2e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OPEFLCOJ_01164 1.6e-96 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OPEFLCOJ_01165 3.5e-285 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
OPEFLCOJ_01166 4.3e-42 S COG NOG14552 non supervised orthologous group
OPEFLCOJ_01167 5.3e-43
OPEFLCOJ_01170 1.6e-08
OPEFLCOJ_01171 4e-08
OPEFLCOJ_01175 4.3e-42 S COG NOG14552 non supervised orthologous group
OPEFLCOJ_01176 5.3e-43
OPEFLCOJ_01177 2.7e-182 yaaC S YaaC-like Protein
OPEFLCOJ_01178 1.5e-272 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
OPEFLCOJ_01179 3.2e-250 dacA 3.4.16.4 M Belongs to the peptidase S11 family
OPEFLCOJ_01180 1.6e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
OPEFLCOJ_01181 4.4e-103 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
OPEFLCOJ_01182 2.9e-211 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OPEFLCOJ_01183 2.9e-09
OPEFLCOJ_01184 1.3e-125 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
OPEFLCOJ_01185 5.4e-118 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
OPEFLCOJ_01186 6.4e-251 yaaH M Glycoside Hydrolase Family
OPEFLCOJ_01187 1e-87 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
OPEFLCOJ_01188 7e-311 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OPEFLCOJ_01189 1.3e-35 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OPEFLCOJ_01190 1.5e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OPEFLCOJ_01191 6.9e-09 S Protein of unknown function (DUF2508)
OPEFLCOJ_01192 5.7e-37 bofA S Sigma-K factor-processing regulatory protein BofA
OPEFLCOJ_01193 1.6e-41 S COG NOG14552 non supervised orthologous group
OPEFLCOJ_01196 1.7e-41
OPEFLCOJ_01197 3.3e-69 yfiL V ABC transporter
OPEFLCOJ_01198 4.7e-29 V Transport permease protein
OPEFLCOJ_01199 3.4e-14
OPEFLCOJ_01200 1.9e-89 sagB C Nitroreductase family
OPEFLCOJ_01201 1.8e-66
OPEFLCOJ_01202 2.8e-137 sagD S YcaO cyclodehydratase, ATP-ad Mg2+-binding
OPEFLCOJ_01204 5.6e-30 L PFAM transposase IS4 family protein
OPEFLCOJ_01205 5.4e-75 ctsR K Belongs to the CtsR family
OPEFLCOJ_01206 6.1e-102 mcsA 2.7.14.1 S protein with conserved CXXC pairs
OPEFLCOJ_01207 7.8e-194 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
OPEFLCOJ_01208 0.0 clpC O Belongs to the ClpA ClpB family
OPEFLCOJ_01210 9.1e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OPEFLCOJ_01211 4e-198 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
OPEFLCOJ_01212 1.5e-121 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
OPEFLCOJ_01213 1.1e-83 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
OPEFLCOJ_01214 1.8e-281 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OPEFLCOJ_01215 6.3e-109 cysE 2.3.1.30 E Serine acetyltransferase
OPEFLCOJ_01216 1.7e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
OPEFLCOJ_01217 7.9e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
OPEFLCOJ_01218 3.3e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OPEFLCOJ_01219 8.7e-90 yacP S RNA-binding protein containing a PIN domain
OPEFLCOJ_01220 2.4e-113 sigH K Belongs to the sigma-70 factor family
OPEFLCOJ_01222 1e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
OPEFLCOJ_01223 1.4e-95 nusG K Participates in transcription elongation, termination and antitermination
OPEFLCOJ_01224 1.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OPEFLCOJ_01225 9.5e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
OPEFLCOJ_01227 5.4e-81 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OPEFLCOJ_01228 1.3e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
OPEFLCOJ_01229 4.2e-112 rsmC 2.1.1.172 J Methyltransferase
OPEFLCOJ_01230 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OPEFLCOJ_01231 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OPEFLCOJ_01232 2.6e-36 rplGB J Belongs to the eukaryotic ribosomal protein eL8 family
OPEFLCOJ_01233 8.6e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OPEFLCOJ_01234 9.3e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
OPEFLCOJ_01235 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OPEFLCOJ_01236 2.7e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OPEFLCOJ_01237 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
OPEFLCOJ_01238 5.7e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OPEFLCOJ_01239 5e-108 rplD J Forms part of the polypeptide exit tunnel
OPEFLCOJ_01240 1.7e-42 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
OPEFLCOJ_01241 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OPEFLCOJ_01242 2.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OPEFLCOJ_01243 6.6e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OPEFLCOJ_01244 2.3e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OPEFLCOJ_01245 9.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OPEFLCOJ_01246 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
OPEFLCOJ_01247 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OPEFLCOJ_01248 1.5e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OPEFLCOJ_01249 1.7e-57 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OPEFLCOJ_01250 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OPEFLCOJ_01251 5.8e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OPEFLCOJ_01252 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OPEFLCOJ_01253 7.1e-95 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OPEFLCOJ_01254 6.1e-58 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OPEFLCOJ_01255 4.7e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OPEFLCOJ_01256 7e-23 rpmD J Ribosomal protein L30
OPEFLCOJ_01257 1.2e-71 rplO J binds to the 23S rRNA
OPEFLCOJ_01258 1.4e-229 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
OPEFLCOJ_01259 1.7e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
OPEFLCOJ_01260 2.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OPEFLCOJ_01261 1.8e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OPEFLCOJ_01262 5.2e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OPEFLCOJ_01263 6.9e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OPEFLCOJ_01264 2.8e-59 rplQ J Ribosomal protein L17
OPEFLCOJ_01266 2.7e-157 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OPEFLCOJ_01267 6.4e-162 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OPEFLCOJ_01268 6e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OPEFLCOJ_01269 3.2e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
OPEFLCOJ_01270 9.9e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OPEFLCOJ_01271 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
OPEFLCOJ_01272 0.0 katE 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
OPEFLCOJ_01273 0.0 S type I phosphodiesterase nucleotide pyrophosphatase
OPEFLCOJ_01275 4.4e-227 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
OPEFLCOJ_01276 7.2e-112 cysC 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
OPEFLCOJ_01277 1.9e-275 lysP E amino acid
OPEFLCOJ_01278 8.8e-83 ybaK S Protein of unknown function (DUF2521)
OPEFLCOJ_01279 6.2e-131 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OPEFLCOJ_01280 1.9e-197 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
OPEFLCOJ_01281 4.8e-70 gerD S Spore gernimation protein
OPEFLCOJ_01282 3.9e-108 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
OPEFLCOJ_01283 1.5e-10 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
OPEFLCOJ_01284 2.2e-187 S Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase
OPEFLCOJ_01285 1.6e-137 pdaB 3.5.1.104 G xylanase chitin deacetylase
OPEFLCOJ_01286 2.6e-30
OPEFLCOJ_01287 6e-263 cydA 1.10.3.14 C oxidase, subunit
OPEFLCOJ_01288 8.4e-182 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
OPEFLCOJ_01289 0.0 cydD V ATP-binding
OPEFLCOJ_01290 0.0 cydD V ATP-binding protein
OPEFLCOJ_01291 1.6e-140 IQ Enoyl-(Acyl carrier protein) reductase
OPEFLCOJ_01292 4.3e-42 S COG NOG14552 non supervised orthologous group
OPEFLCOJ_01293 1.1e-40
OPEFLCOJ_01298 1.7e-07
OPEFLCOJ_01299 1.5e-07
OPEFLCOJ_01303 1.1e-169 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
OPEFLCOJ_01305 7.2e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
OPEFLCOJ_01306 2.2e-116 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
OPEFLCOJ_01307 9.4e-147 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OPEFLCOJ_01308 9.3e-223 ybbR S protein conserved in bacteria
OPEFLCOJ_01309 4.2e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OPEFLCOJ_01310 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
OPEFLCOJ_01312 7.9e-99 M1-431 S Protein of unknown function (DUF1706)
OPEFLCOJ_01313 3.6e-145 3.1.2.21 I Acyl-ACP thioesterase
OPEFLCOJ_01314 5.1e-87
OPEFLCOJ_01315 1.4e-82 S cellulose binding
OPEFLCOJ_01316 6.7e-248 L PFAM Transposase, IS4-like
OPEFLCOJ_01317 3.3e-217 G Major facilitator Superfamily
OPEFLCOJ_01318 1.3e-83 S Pfam:DUF1399
OPEFLCOJ_01319 1.3e-199 EGP Major facilitator Superfamily
OPEFLCOJ_01320 1.9e-142 K Bacterial regulatory helix-turn-helix protein, lysR family
OPEFLCOJ_01321 0.0 L Domain of unknown function (DUF4277)
OPEFLCOJ_01322 2.4e-138 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
OPEFLCOJ_01323 1.6e-260 NT Chemoreceptor zinc-binding domain
OPEFLCOJ_01324 8.3e-114 S Putative adhesin
OPEFLCOJ_01325 3.9e-96 S Protein of unknown function (DUF1700)
OPEFLCOJ_01326 1.3e-54 K PadR family transcriptional regulator
OPEFLCOJ_01327 1.7e-182 NT chemotaxis protein
OPEFLCOJ_01328 1.5e-253 EGP Major facilitator superfamily
OPEFLCOJ_01329 1.3e-102 Q Isochorismatase family
OPEFLCOJ_01330 1.1e-107 K Transcriptional regulator
OPEFLCOJ_01331 6.4e-60
OPEFLCOJ_01332 6e-127
OPEFLCOJ_01333 5.2e-44 ltaA 4.1.2.48 E L-allo-threonine aldolase activity
OPEFLCOJ_01334 1.4e-212 EGP Major Facilitator Superfamily
OPEFLCOJ_01335 3.9e-170 F ATP-grasp domain
OPEFLCOJ_01336 1.6e-07 F ATP-grasp domain
OPEFLCOJ_01337 3.2e-211 K helix_turn_helix, Arsenical Resistance Operon Repressor
OPEFLCOJ_01338 1.7e-51 ykvR S Protein of unknown function (DUF3219)
OPEFLCOJ_01339 7.2e-186 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OPEFLCOJ_01341 1.2e-217 yjbB G Major Facilitator Superfamily
OPEFLCOJ_01343 4.9e-96 rimJ 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
OPEFLCOJ_01345 1e-87 2.3.1.128 J Acetyltransferase (GNAT) domain
OPEFLCOJ_01346 3e-248 L PFAM Transposase, IS4-like
OPEFLCOJ_01347 1.9e-47 3.6.1.55 F GDP-mannose mannosyl hydrolase activity
OPEFLCOJ_01349 0.0 L Domain of unknown function (DUF4277)
OPEFLCOJ_01350 1.7e-116 E lactoylglutathione lyase activity
OPEFLCOJ_01351 1.6e-233 lmrP E Transmembrane secretion effector
OPEFLCOJ_01352 1.1e-74 yycN 2.3.1.128, 2.3.1.57 K FR47-like protein
OPEFLCOJ_01353 2.8e-132 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
OPEFLCOJ_01354 1.9e-127 V CAAX protease self-immunity
OPEFLCOJ_01355 3.3e-46 L transposase, IS605 OrfB family
OPEFLCOJ_01356 3.4e-239 L Transposase DDE domain group 1
OPEFLCOJ_01357 2.8e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 I Hydroxymethylglutaryl-coenzyme A reductase
OPEFLCOJ_01358 2.9e-22
OPEFLCOJ_01359 8e-63 L IS66 Orf2 like protein
OPEFLCOJ_01360 8e-140 L PFAM Transposase, IS4-like
OPEFLCOJ_01361 6.3e-66 L PFAM Transposase, IS4-like
OPEFLCOJ_01362 5.9e-307 L Transposase IS66 family
OPEFLCOJ_01363 6.9e-253 L PFAM Transposase, IS4-like
OPEFLCOJ_01364 2.9e-129 L DNA synthesis involved in DNA repair
OPEFLCOJ_01365 8.7e-137 3.6.4.12 L ATP-dependent DNA helicase activity
OPEFLCOJ_01366 1.3e-59 L resolvase
OPEFLCOJ_01367 2.3e-248 L PFAM Transposase, IS4-like
OPEFLCOJ_01368 3e-218 EGP Major facilitator superfamily
OPEFLCOJ_01369 1.1e-262 yheS_2 S ABC transporter
OPEFLCOJ_01370 7.9e-47 S Nucleotidyltransferase domain
OPEFLCOJ_01371 2.1e-173 2.1.1.21 E Conserved region in glutamate synthase
OPEFLCOJ_01372 4.8e-165 mta K TipAS antibiotic-recognition domain
OPEFLCOJ_01373 2.7e-95 K TipAS antibiotic-recognition domain
OPEFLCOJ_01374 5.1e-185 EGP Major facilitator Superfamily
OPEFLCOJ_01375 1.5e-70 2.3.1.128 K PFAM GCN5-related N-acetyltransferase
OPEFLCOJ_01376 1.3e-70 S Nucleotidyltransferase domain
OPEFLCOJ_01377 7.3e-123 vatD S Bacterial transferase hexapeptide (six repeats)
OPEFLCOJ_01378 3.6e-165 MA20_01270 K AraC family transcriptional regulator
OPEFLCOJ_01379 1.4e-25 S Rifampin ADP-ribosyl transferase
OPEFLCOJ_01380 1e-101 S Rifampin ADP-ribosyl transferase
OPEFLCOJ_01381 2.2e-10 L PFAM transposase, IS4 family protein
OPEFLCOJ_01382 4.6e-18
OPEFLCOJ_01383 2e-43 L PFAM Transposase, IS4-like
OPEFLCOJ_01384 9.1e-64 L PFAM Transposase, IS4-like
OPEFLCOJ_01385 1.7e-10
OPEFLCOJ_01386 3.4e-73 tasA S Cell division protein FtsN
OPEFLCOJ_01387 9.4e-48 S Camelysin metallo-endopeptidase
OPEFLCOJ_01389 1.6e-61 sipW 3.4.21.89 U Signal peptidase
OPEFLCOJ_01390 1.7e-51 S cell adhesion involved in biofilm formation
OPEFLCOJ_01391 1.3e-96 XK27_04080 H RibD C-terminal domain
OPEFLCOJ_01393 3.4e-266 L Transposase
OPEFLCOJ_01394 1.6e-121 S Antitoxin Phd_YefM, type II toxin-antitoxin system
OPEFLCOJ_01395 1e-270 L RNA-directed DNA polymerase (reverse transcriptase)
OPEFLCOJ_01396 1e-223 mvaS 2.3.3.10 I synthase
OPEFLCOJ_01397 8.5e-265 S PFAM Uncharacterised protein family UPF0236
OPEFLCOJ_01398 7.4e-214 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
OPEFLCOJ_01399 2.9e-54 S DsrE/DsrF-like family
OPEFLCOJ_01400 1.1e-77
OPEFLCOJ_01401 3.5e-185 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OPEFLCOJ_01403 3.5e-177 proV E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
OPEFLCOJ_01404 5.8e-275 proWX EM COG1174 ABC-type proline glycine betaine transport systems, permease component
OPEFLCOJ_01405 2.8e-82 2.7.1.199 G COG2190 Phosphotransferase system IIA components
OPEFLCOJ_01406 2.9e-265 treP 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OPEFLCOJ_01407 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
OPEFLCOJ_01408 2.2e-131 treR K transcriptional
OPEFLCOJ_01409 1.3e-230 EG COG2610 H gluconate symporter and related permeases
OPEFLCOJ_01411 1.1e-308 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
OPEFLCOJ_01412 2.2e-125 gntR K transcriptional
OPEFLCOJ_01413 6e-171 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
OPEFLCOJ_01415 1.7e-81 fld C Flavodoxin
OPEFLCOJ_01416 1.7e-204 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
OPEFLCOJ_01417 9.5e-138 4.1.99.16, 4.2.3.22, 4.2.3.75 T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
OPEFLCOJ_01419 0.0 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
OPEFLCOJ_01420 2.8e-29 P Heavy-metal-associated domain
OPEFLCOJ_01422 0.0 nrdA 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OPEFLCOJ_01423 1.6e-87 fld C Flavodoxin
OPEFLCOJ_01424 4e-195 nrdB 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OPEFLCOJ_01425 8.9e-110 plsY 2.3.1.15 I Belongs to the PlsY family
OPEFLCOJ_01426 2.8e-207 crtQ M Glycosyl transferase family 21
OPEFLCOJ_01427 4.6e-150 S transposase or invertase
OPEFLCOJ_01428 6.9e-18 S transposase or invertase
OPEFLCOJ_01429 3.2e-16 S transposase or invertase
OPEFLCOJ_01430 2.2e-265 S PFAM Uncharacterised protein family UPF0236
OPEFLCOJ_01431 6.1e-93 Q Thioesterase superfamily
OPEFLCOJ_01432 2.8e-171 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
OPEFLCOJ_01433 1e-48 sugE P Multidrug resistance protein
OPEFLCOJ_01434 6.6e-54 ykkC P Multidrug resistance protein
OPEFLCOJ_01435 2e-138 yfcA S membrane transporter protein
OPEFLCOJ_01436 1.5e-181 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OPEFLCOJ_01437 1.2e-178 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OPEFLCOJ_01438 1.6e-169 fhuD P Periplasmic binding protein
OPEFLCOJ_01439 1.8e-150 fhuC 3.6.3.34 HP ABC transporter
OPEFLCOJ_01440 6.5e-198 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
OPEFLCOJ_01441 1.6e-114
OPEFLCOJ_01442 2e-106
OPEFLCOJ_01443 2e-106
OPEFLCOJ_01444 3.8e-128 yeeN K transcriptional regulatory protein
OPEFLCOJ_01445 2.2e-190 T Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor)
OPEFLCOJ_01446 1.5e-241 MA20_26760 1.3.8.7 I COG1960 Acyl-CoA dehydrogenases
OPEFLCOJ_01447 2.4e-136 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OPEFLCOJ_01448 1.6e-173 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OPEFLCOJ_01449 1.5e-74 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OPEFLCOJ_01450 6.7e-96 K Transcriptional regulator
OPEFLCOJ_01452 5.6e-68 S Thioesterase-like superfamily
OPEFLCOJ_01453 3.9e-198 S Phosphotransferase enzyme family
OPEFLCOJ_01454 1.6e-266 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OPEFLCOJ_01455 1.1e-269 yobO M Pectate lyase superfamily protein
OPEFLCOJ_01456 1.9e-07
OPEFLCOJ_01457 2.2e-139 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
OPEFLCOJ_01458 6e-140 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
OPEFLCOJ_01459 7.6e-132 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
OPEFLCOJ_01460 1.7e-108 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
OPEFLCOJ_01461 7e-95 ywhH S Aminoacyl-tRNA editing domain
OPEFLCOJ_01462 1.1e-203 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
OPEFLCOJ_01463 0.0 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OPEFLCOJ_01464 5.1e-190 2.7.7.65 T Diguanylate cyclase, GGDEF domain
OPEFLCOJ_01466 1.3e-165 EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
OPEFLCOJ_01467 2.6e-158 S Nuclease-related domain
OPEFLCOJ_01468 8.4e-45
OPEFLCOJ_01469 9.8e-30
OPEFLCOJ_01470 1.9e-164 czcD P COG1230 Co Zn Cd efflux system component
OPEFLCOJ_01471 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
OPEFLCOJ_01472 2.2e-114 M Glycosyltransferase like family 2
OPEFLCOJ_01473 8.8e-171 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases C terminal
OPEFLCOJ_01474 9.1e-173 mvaD 4.1.1.33 I GHMP kinases N terminal domain
OPEFLCOJ_01475 1e-188 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases C terminal
OPEFLCOJ_01476 2.9e-111 yhfK GM NmrA-like family
OPEFLCOJ_01477 6.4e-22
OPEFLCOJ_01478 4e-75 S protein conserved in bacteria
OPEFLCOJ_01479 1.3e-238 L Transposase DDE domain group 1
OPEFLCOJ_01480 1e-231 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
OPEFLCOJ_01481 6.5e-111 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OPEFLCOJ_01482 2.3e-38 gcvR T Belongs to the UPF0237 family
OPEFLCOJ_01483 4.1e-248 XK27_08635 S UPF0210 protein
OPEFLCOJ_01484 1.6e-191 ptxS K transcriptional
OPEFLCOJ_01485 3.5e-132 kguE 2.7.1.45 G Xylose isomerase domain protein TIM barrel
OPEFLCOJ_01486 2.5e-175 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
OPEFLCOJ_01487 2.3e-240 G Major Facilitator Superfamily
OPEFLCOJ_01488 1.2e-93 hxlA 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
OPEFLCOJ_01489 1.4e-93 hxlB 4.1.2.14, 4.1.2.43, 4.1.3.42, 5.3.1.27 M SIS domain
OPEFLCOJ_01491 3.4e-83 cotF M Spore coat protein
OPEFLCOJ_01492 1e-173 iolS C Aldo keto reductase
OPEFLCOJ_01493 4.2e-98 ydjA C Nitroreductase family
OPEFLCOJ_01494 1.1e-253 E COG1113 Gamma-aminobutyrate permease and related permeases
OPEFLCOJ_01495 1.7e-17
OPEFLCOJ_01496 9.6e-275 dtpT E amino acid peptide transporter
OPEFLCOJ_01497 8.4e-279 lysP E amino acid
OPEFLCOJ_01499 2.3e-99 puuR K Cupin domain
OPEFLCOJ_01500 2.5e-211 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
OPEFLCOJ_01501 2.8e-140 potB E COG1176 ABC-type spermidine putrescine transport system, permease component I
OPEFLCOJ_01502 9.2e-139 potC E COG1177 ABC-type spermidine putrescine transport system, permease component II
OPEFLCOJ_01503 6.4e-204 potD E COG0687 Spermidine putrescine-binding periplasmic protein
OPEFLCOJ_01505 5.6e-269 H HemY protein
OPEFLCOJ_01506 9.7e-253 E amino acid
OPEFLCOJ_01507 2.7e-134 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
OPEFLCOJ_01508 1.1e-272 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
OPEFLCOJ_01509 7.7e-137 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
OPEFLCOJ_01510 3.6e-221 pucR QT Transcriptional regulator
OPEFLCOJ_01511 1.7e-265 2.6.1.55 H Aminotransferase class-III
OPEFLCOJ_01512 3.6e-213 C alcohol dehydrogenase
OPEFLCOJ_01513 1.1e-231 amaB 3.5.1.6, 3.5.1.87 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
OPEFLCOJ_01514 1.6e-293 FH COG1953 Cytosine uracil thiamine allantoin permeases
OPEFLCOJ_01515 6.7e-251 gltD 1.3.1.1 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
OPEFLCOJ_01516 4.3e-231 preA 1.3.1.1 CF dihydroorotate dehydrogenase
OPEFLCOJ_01517 2.2e-273 hyuA 3.5.2.2 F Amidohydrolase family
OPEFLCOJ_01519 5.7e-253 E Amino acid permease
OPEFLCOJ_01521 6e-224 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
OPEFLCOJ_01522 3.4e-233 amt P Ammonium transporter
OPEFLCOJ_01523 5.4e-292 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
OPEFLCOJ_01524 1.6e-120 citT T response regulator
OPEFLCOJ_01525 6.6e-238 citH C Citrate transporter
OPEFLCOJ_01526 2.6e-183 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OPEFLCOJ_01527 0.0 helD 3.6.4.12 L DNA helicase
OPEFLCOJ_01529 3.3e-32
OPEFLCOJ_01530 6.9e-253 L PFAM Transposase, IS4-like
OPEFLCOJ_01531 1.9e-17
OPEFLCOJ_01533 2.5e-30 K Cro/C1-type HTH DNA-binding domain
OPEFLCOJ_01534 2.2e-99 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
OPEFLCOJ_01535 1.4e-147 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
OPEFLCOJ_01536 1.2e-290 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OPEFLCOJ_01537 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OPEFLCOJ_01538 3.6e-214 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OPEFLCOJ_01539 6.6e-122 K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
OPEFLCOJ_01541 3.6e-131 ric D Di-iron-containing protein involved in the repair of iron-sulfur clusters
OPEFLCOJ_01542 6.4e-96 S Belongs to the UPF0312 family
OPEFLCOJ_01543 7.1e-214 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
OPEFLCOJ_01546 5.9e-191 T HD domain
OPEFLCOJ_01548 8.6e-278 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
OPEFLCOJ_01550 0.0 ydaO E amino acid
OPEFLCOJ_01551 1.6e-146 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
OPEFLCOJ_01552 3e-24 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
OPEFLCOJ_01554 2.4e-267 S PFAM Uncharacterised protein family UPF0236
OPEFLCOJ_01555 1e-171 ydbI S AI-2E family transporter
OPEFLCOJ_01556 1.5e-132 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OPEFLCOJ_01557 1.3e-135 glnH ET Belongs to the bacterial solute-binding protein 3 family
OPEFLCOJ_01558 1.2e-109 gluC P ABC transporter
OPEFLCOJ_01559 2.3e-117 glnP P ABC transporter
OPEFLCOJ_01560 1.7e-69 K helix_turn_helix gluconate operon transcriptional repressor
OPEFLCOJ_01561 7.6e-197 S Protein of unknown function (DUF1648)
OPEFLCOJ_01562 9.6e-55 yodB K transcriptional
OPEFLCOJ_01564 2.2e-235 S SNARE associated Golgi protein
OPEFLCOJ_01565 4.2e-96 yngC S membrane-associated protein
OPEFLCOJ_01566 9.5e-159 msrR K COG1316 Transcriptional regulator
OPEFLCOJ_01568 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
OPEFLCOJ_01569 0.0 metH 2.1.1.13 E Methionine synthase
OPEFLCOJ_01570 2.2e-11 csbD S Belongs to the UPF0337 (CsbD) family
OPEFLCOJ_01571 2e-88 K ComK protein
OPEFLCOJ_01572 2.2e-105 sigS 2.7.7.6 K Belongs to the sigma-70 factor family. ECF subfamily
OPEFLCOJ_01573 7.6e-133 E lipolytic protein G-D-S-L family
OPEFLCOJ_01574 2.2e-123 ywqC M biosynthesis protein
OPEFLCOJ_01575 8.8e-112 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
OPEFLCOJ_01576 1e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
OPEFLCOJ_01577 1.1e-161 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
OPEFLCOJ_01578 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
OPEFLCOJ_01579 1.9e-172 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
OPEFLCOJ_01580 8.2e-151 F ATP-grasp domain
OPEFLCOJ_01581 1e-101 5.1.3.2 GM NAD(P)H-binding
OPEFLCOJ_01582 3.4e-80 epsL M Bacterial sugar transferase
OPEFLCOJ_01583 8.5e-139 M Glycosyl transferases group 1
OPEFLCOJ_01584 2.1e-64 S O-antigen polysaccharide polymerase Wzy
OPEFLCOJ_01585 3.8e-51 cpsIaJ M Glycosyltransferase group 2 family protein
OPEFLCOJ_01586 1.4e-126 S polysaccharide biosynthetic process
OPEFLCOJ_01588 5e-132 L Transposase, IS4 family protein
OPEFLCOJ_01589 2.2e-109 3.2.2.24 O ADP-ribosylglycohydrolase
OPEFLCOJ_01590 2.1e-277 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
OPEFLCOJ_01591 0.0 M Peptidase M30
OPEFLCOJ_01592 1.4e-245 yicJ G MFS/sugar transport protein
OPEFLCOJ_01593 5.9e-304 2.7.1.12, 2.7.1.17 G xylulose kinase
OPEFLCOJ_01594 1.2e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OPEFLCOJ_01595 9.3e-214 2.7.1.2 GK ROK family
OPEFLCOJ_01596 2e-42 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
OPEFLCOJ_01597 6.9e-161 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
OPEFLCOJ_01598 6.2e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OPEFLCOJ_01599 3.6e-179 3.1.1.5 I Alpha beta hydrolase
OPEFLCOJ_01604 0.0 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
OPEFLCOJ_01606 1.9e-29 yodI
OPEFLCOJ_01607 4.3e-149 yjaZ O Zn-dependent protease
OPEFLCOJ_01608 3.3e-132 yodH Q Methyltransferase
OPEFLCOJ_01610 3.7e-268 S PFAM Uncharacterised protein family UPF0236
OPEFLCOJ_01611 5.3e-122 S PD-(D/E)XK nuclease family transposase
OPEFLCOJ_01612 9.3e-74 2.1.1.113 L N-4 methylation of cytosine
OPEFLCOJ_01613 2.6e-110 S Protein of unknown function DUF262
OPEFLCOJ_01614 3.5e-41
OPEFLCOJ_01615 1.6e-54 L Transposase
OPEFLCOJ_01616 6.1e-73 G PTS system fructose IIA component
OPEFLCOJ_01617 4.3e-147 G PTS system mannose/fructose/sorbose family IID component
OPEFLCOJ_01618 2.8e-140 agaC G PTS system sorbose-specific iic component
OPEFLCOJ_01619 3.9e-81 agaB 2.7.1.191 G PTS system sorbose subfamily IIB component
OPEFLCOJ_01620 6.6e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
OPEFLCOJ_01621 1.4e-130 K UTRA
OPEFLCOJ_01622 5.9e-97 puuR_2 K Cupin domain
OPEFLCOJ_01623 0.0 oplaH 3.5.2.14, 3.5.2.9 EQ COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit
OPEFLCOJ_01624 2e-212 L Transposase
OPEFLCOJ_01625 2.4e-50 oplaH 3.5.2.14, 3.5.2.9 EQ COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit
OPEFLCOJ_01626 0.0 3.5.2.14 EQ COG0146 N-methylhydantoinase B acetone carboxylase, alpha subunit
OPEFLCOJ_01627 3.7e-257 F Permease for cytosine/purines, uracil, thiamine, allantoin
OPEFLCOJ_01628 0.0 K PTS system fructose IIA component
OPEFLCOJ_01629 9.6e-74 2.7.1.191 G PTS system fructose IIA component
OPEFLCOJ_01630 3.4e-80 2.7.1.191 G PTS system mannose fructose sorbose family
OPEFLCOJ_01631 5.2e-134 G PTS system sorbose-specific iic component
OPEFLCOJ_01632 6.1e-143 G PFAM Phosphotransferase system, mannose fructose sorbose family IID component
OPEFLCOJ_01633 5.5e-200 M SIS domain
OPEFLCOJ_01634 3.7e-139 2.7.1.194, 2.7.1.202 GKT COG3711 Transcriptional antiterminator
OPEFLCOJ_01635 8.7e-27 2.7.1.194, 2.7.1.197, 2.7.1.200, 2.7.1.202 G antiterminator
OPEFLCOJ_01636 1.2e-35 2.7.1.197, 2.7.1.200, 2.7.1.202 G PTS galactitol transporter subunit IIA
OPEFLCOJ_01637 2e-29 sgcB 2.7.1.200 G to PTS system galactitol-specific enzyme IIB component
OPEFLCOJ_01638 4.4e-197 G PTS system sugar-specific permease component
OPEFLCOJ_01640 3.6e-73 2.7.1.11, 2.7.1.56 F pfkB family carbohydrate kinase
OPEFLCOJ_01641 3.5e-85 4.1.2.17, 4.1.2.19 G Class II Aldolase and Adducin N-terminal domain
OPEFLCOJ_01642 5.2e-306 K COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
OPEFLCOJ_01643 2e-200 S Protein of unknown function (DUF917)
OPEFLCOJ_01644 5.6e-294 apc3 3.5.2.9 EQ Hydantoinase oxoprolinase
OPEFLCOJ_01645 2.3e-208 codB F cytosine purines uracil thiamine allantoin
OPEFLCOJ_01646 1.3e-204 S Protein of unknown function (DUF917)
OPEFLCOJ_01647 3.1e-292 apc3 3.5.2.9 EQ Hydantoinase/oxoprolinase
OPEFLCOJ_01648 2.4e-181 1.13.12.16, 1.3.1.9 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
OPEFLCOJ_01649 6.4e-68 yjbR S YjbR
OPEFLCOJ_01650 7.6e-52 S Protein of unknown function (DUF1648)
OPEFLCOJ_01652 2e-252 L PFAM Transposase, IS4-like
OPEFLCOJ_01654 8.6e-251 L Metallo-beta-lactamase superfamily
OPEFLCOJ_01655 1.4e-30 S Protein of unknown function (DUF3006)
OPEFLCOJ_01656 0.0 ganB 3.2.1.89 G arabinogalactan
OPEFLCOJ_01657 1.1e-189 csd1 S CRISPR-associated protein, Csd1 family
OPEFLCOJ_01658 4.7e-19 csd2 L CRISPR-associated protein Cas7
OPEFLCOJ_01659 0.0 ybeC E amino acid
OPEFLCOJ_01661 0.0 3.2.1.78 GH26 O cellulase activity
OPEFLCOJ_01662 1.1e-178 K cell envelope-related transcriptional attenuator
OPEFLCOJ_01663 9.5e-51
OPEFLCOJ_01665 1.3e-173 ydhF S Oxidoreductase
OPEFLCOJ_01666 3e-138 S transposase or invertase
OPEFLCOJ_01668 1.2e-52 S Domain of unknown function (DUF3870)
OPEFLCOJ_01669 7.9e-235 B4168_2380 1.3.99.32 I Acyl-CoA dehydrogenase, N-terminal domain
OPEFLCOJ_01670 1e-223 C acyl-CoA transferases carnitine dehydratase
OPEFLCOJ_01671 1e-190 yfmJ S N-terminal domain of oxidoreductase
OPEFLCOJ_01672 5.2e-215 EGP Major facilitator Superfamily
OPEFLCOJ_01673 0.0 2.7.1.202 K transcriptional regulator, MtlR
OPEFLCOJ_01674 4.2e-53 licB 2.7.1.196, 2.7.1.205 G phosphotransferase system
OPEFLCOJ_01675 3.9e-51 chbA 2.7.1.196, 2.7.1.205 G PTS cellobiose transporter subunit IIA
OPEFLCOJ_01676 1.2e-210 S Bacterial protein of unknown function (DUF871)
OPEFLCOJ_01677 1e-232 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OPEFLCOJ_01678 3e-254 gph G MFS/sugar transport protein
OPEFLCOJ_01680 1.8e-251 E Amino acid permease
OPEFLCOJ_01681 4.8e-210 K helix_turn_helix, arabinose operon control protein
OPEFLCOJ_01682 4e-223 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
OPEFLCOJ_01683 1.3e-184 tdh 4.2.1.45 GM GDP-mannose 4,6 dehydratase
OPEFLCOJ_01684 7.9e-73 K transcriptional
OPEFLCOJ_01685 1.3e-205 EGP Major facilitator Superfamily
OPEFLCOJ_01686 1.3e-174 K Transcriptional regulator
OPEFLCOJ_01688 0.0 bga2 3.2.1.23 G beta-galactosidase
OPEFLCOJ_01689 3.4e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
OPEFLCOJ_01690 1.1e-169 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
OPEFLCOJ_01691 3.4e-115 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
OPEFLCOJ_01692 5.7e-211 opuCA E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
OPEFLCOJ_01693 4.5e-97 yvbF K Belongs to the GbsR family
OPEFLCOJ_01694 7.9e-97 maa 2.3.1.79 S COG0110 Acetyltransferase (isoleucine patch superfamily)
OPEFLCOJ_01695 3.6e-191 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OPEFLCOJ_01696 3.4e-266 L Transposase
OPEFLCOJ_01697 8.5e-190 L ISXO2-like transposase domain
OPEFLCOJ_01698 7.5e-103 yyaP 1.5.1.3 H RibD C-terminal domain
OPEFLCOJ_01699 3.2e-46
OPEFLCOJ_01700 4.9e-110 yjlB S Cupin domain
OPEFLCOJ_01701 3.1e-150 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
OPEFLCOJ_01702 2.9e-136 yflN_1 S Metallo-beta-lactamase superfamily
OPEFLCOJ_01703 8.8e-270 L RNA-directed DNA polymerase (reverse transcriptase)
OPEFLCOJ_01704 5.1e-178 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
OPEFLCOJ_01705 1.7e-99 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
OPEFLCOJ_01706 1.4e-303 comM O Mg chelatase subunit ChlI
OPEFLCOJ_01707 1.1e-149 S transposase or invertase
OPEFLCOJ_01708 4.6e-21
OPEFLCOJ_01709 2.7e-202 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
OPEFLCOJ_01710 3.2e-248 csbC EGP Major facilitator Superfamily
OPEFLCOJ_01711 8.9e-292 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
OPEFLCOJ_01712 1.4e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
OPEFLCOJ_01713 7.2e-217 xylR GK ROK family
OPEFLCOJ_01714 3e-209 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OPEFLCOJ_01715 7.6e-160 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
OPEFLCOJ_01716 7.5e-294 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
OPEFLCOJ_01717 2.1e-205 nifS 2.8.1.7 E Cysteine desulfurase
OPEFLCOJ_01718 3.2e-95 S NYN domain
OPEFLCOJ_01719 1.2e-143 focA P Formate nitrite
OPEFLCOJ_01721 1.7e-264 NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
OPEFLCOJ_01722 3.6e-42 cbiQ P COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters
OPEFLCOJ_01723 2.5e-31 ykoD P ABC transporter, ATP-binding protein
OPEFLCOJ_01724 2.3e-45 S UPF0397 protein
OPEFLCOJ_01725 4.4e-20 S UPF0397 protein
OPEFLCOJ_01726 9.7e-163 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
OPEFLCOJ_01727 1.5e-122 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
OPEFLCOJ_01728 3.7e-252 EG COG2610 H gluconate symporter and related permeases
OPEFLCOJ_01729 1.3e-279 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OPEFLCOJ_01730 7.8e-219 adhB 1.1.1.1, 1.1.1.202 C alcohol dehydrogenase
OPEFLCOJ_01731 0.0 KT Transcriptional regulator
OPEFLCOJ_01732 0.0 xylS 3.2.1.20 GH31 G Domain of unknown function (DUF5110)
OPEFLCOJ_01733 1.5e-15 xylS 3.2.1.20 GH31 G Domain of unknown function (DUF5110)
OPEFLCOJ_01734 7.2e-282 Otg1 S Predicted membrane protein (DUF2339)
OPEFLCOJ_01735 3.5e-230 L PFAM Transposase, IS116 IS110 IS902
OPEFLCOJ_01736 1.8e-104 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
OPEFLCOJ_01737 2.9e-195 S Metallo-beta-lactamase superfamily
OPEFLCOJ_01738 1.1e-106 K Bacterial regulatory proteins, tetR family
OPEFLCOJ_01739 0.0 fldZ 1.3.1.31 C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
OPEFLCOJ_01740 5.3e-12 S PFAM Uncharacterised protein family UPF0236
OPEFLCOJ_01741 2.1e-207 ysdC G COG1363 Cellulase M and related proteins
OPEFLCOJ_01743 4e-44
OPEFLCOJ_01744 6.2e-52 T ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OPEFLCOJ_01745 1.6e-108
OPEFLCOJ_01746 4.2e-43
OPEFLCOJ_01748 1.2e-49 S double-stranded DNA endodeoxyribonuclease activity
OPEFLCOJ_01749 2.1e-13 S double-stranded DNA endodeoxyribonuclease activity
OPEFLCOJ_01750 2.6e-132 VVA0018 T Histidine kinase
OPEFLCOJ_01751 2e-129 T helix_turn_helix, arabinose operon control protein
OPEFLCOJ_01752 9.7e-08 E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OPEFLCOJ_01753 1.7e-170 3.5.1.4 C Acetamidase
OPEFLCOJ_01754 7.2e-16 puuP_1 E Amino acid permease
OPEFLCOJ_01755 2.1e-180 puuP_1 E Amino acid permease
OPEFLCOJ_01756 2.3e-21 S Zinc-ribbon containing domain
OPEFLCOJ_01757 1.4e-298 yvfH C L-lactate permease
OPEFLCOJ_01758 1.1e-122 yvfI K COG2186 Transcriptional regulators
OPEFLCOJ_01759 7.4e-230 lysN EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OPEFLCOJ_01760 3.9e-60
OPEFLCOJ_01763 1.3e-168 lytR_1 K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
OPEFLCOJ_01764 2.3e-218 EGP Major facilitator Superfamily
OPEFLCOJ_01765 3.2e-200 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
OPEFLCOJ_01766 2.2e-16 S YvrJ protein family
OPEFLCOJ_01767 9.8e-11 S Protein of unknown function (DUF2922)
OPEFLCOJ_01768 5.8e-11 S Protein of unknown function (DUF1659)
OPEFLCOJ_01769 0.0 O Belongs to the peptidase S8 family
OPEFLCOJ_01770 1.1e-68 S Protein of unknown function (DUF2512)
OPEFLCOJ_01771 2.9e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
OPEFLCOJ_01772 4e-53 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIB subunit
OPEFLCOJ_01773 7.1e-81
OPEFLCOJ_01774 4.1e-248 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OPEFLCOJ_01775 9.8e-293 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OPEFLCOJ_01776 0.0 2.7.1.202 K transcriptional regulator, MtlR
OPEFLCOJ_01777 1e-156 kdsA 2.5.1.55 M Belongs to the KdsA family
OPEFLCOJ_01778 1.8e-176 kdsD 5.3.1.13 M Belongs to the SIS family. GutQ KpsF subfamily
OPEFLCOJ_01779 1.6e-163 V ATPases associated with a variety of cellular activities
OPEFLCOJ_01780 4.3e-09
OPEFLCOJ_01781 2.6e-230 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
OPEFLCOJ_01782 1.9e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
OPEFLCOJ_01783 1.2e-07 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
OPEFLCOJ_01784 0.0 treP 2.4.1.64 GH65 G Glycoside hydrolase, family 65
OPEFLCOJ_01785 1.1e-147 G Binding-protein-dependent transport system inner membrane component
OPEFLCOJ_01786 6.5e-221 sugA G Binding-protein-dependent transport system inner membrane component
OPEFLCOJ_01787 8.1e-227 G Bacterial extracellular solute-binding protein
OPEFLCOJ_01788 1.3e-131 K helix_turn_helix, arabinose operon control protein
OPEFLCOJ_01789 6.3e-139 gumM 2.4.1.187, 2.4.1.252 GT26,GT4 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
OPEFLCOJ_01790 1.5e-52 S Iron-sulphur cluster biosynthesis
OPEFLCOJ_01791 2.2e-179 yhfP 1.1.1.1 C Quinone oxidoreductase
OPEFLCOJ_01792 3.9e-159 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OPEFLCOJ_01793 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
OPEFLCOJ_01794 0.0 prtS 3.4.21.110, 3.4.21.96 O Belongs to the peptidase S8 family
OPEFLCOJ_01795 1e-87
OPEFLCOJ_01796 4.1e-147 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
OPEFLCOJ_01797 1.8e-133 IQ Short-chain dehydrogenase reductase sdr
OPEFLCOJ_01798 5.5e-30 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
OPEFLCOJ_01799 5.2e-110 cyoC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
OPEFLCOJ_01800 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OPEFLCOJ_01801 1.7e-160 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
OPEFLCOJ_01802 4.4e-123 yhcW 5.4.2.6 S hydrolase
OPEFLCOJ_01803 2.6e-166 lytR_1 K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
OPEFLCOJ_01804 2.4e-130 M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OPEFLCOJ_01805 2e-129 macB V ABC transporter, ATP-binding protein
OPEFLCOJ_01806 7.3e-153 V COG0577 ABC-type antimicrobial peptide transport system, permease component
OPEFLCOJ_01807 2.5e-121 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OPEFLCOJ_01808 3.8e-232 T PhoQ Sensor
OPEFLCOJ_01809 1.3e-21
OPEFLCOJ_01810 0.0 ppc 4.1.1.31 C Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
OPEFLCOJ_01812 9.9e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
OPEFLCOJ_01813 1.8e-74 yabE S 3D domain
OPEFLCOJ_01815 5.9e-97 relA_2 2.7.6.5, 3.1.7.2 KT HD domain
OPEFLCOJ_01816 0.0 pip S YhgE Pip N-terminal domain protein
OPEFLCOJ_01817 3.7e-48 yqgV S Thiamine-binding protein
OPEFLCOJ_01818 7.6e-202 pgl 3.1.1.31 G 6-phosphogluconolactonase
OPEFLCOJ_01819 0.0 S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OPEFLCOJ_01820 0.0 levR K PTS system fructose IIA component
OPEFLCOJ_01821 2.4e-84 manX 2.7.1.191 G PTS system sorbose subfamily IIB component
OPEFLCOJ_01822 2.4e-178 manL 2.7.1.191 G PTS system mannose fructose sorbose family
OPEFLCOJ_01823 3.6e-119 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
OPEFLCOJ_01824 1.9e-169 manN G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
OPEFLCOJ_01825 9.1e-65 manO S Domain of unknown function (DUF956)
OPEFLCOJ_01826 1.1e-211 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
OPEFLCOJ_01827 5.6e-280 prpD 4.2.1.79 S 2-methylcitrate dehydratase
OPEFLCOJ_01828 4.5e-166 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
OPEFLCOJ_01829 1.2e-80 S Heat induced stress protein YflT
OPEFLCOJ_01830 4.7e-274 nylA 3.5.1.4 J Belongs to the amidase family
OPEFLCOJ_01831 3.8e-51 M1-594 S Thiamine-binding protein
OPEFLCOJ_01832 4.8e-140 ssuC_1 P binding-protein-dependent transport systems inner membrane component
OPEFLCOJ_01833 2.1e-185 M1-596 P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
OPEFLCOJ_01834 1.6e-140 P ABC transporter, ATP-binding protein
OPEFLCOJ_01835 7.2e-164 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
OPEFLCOJ_01836 6.3e-196 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OPEFLCOJ_01837 8.4e-243 hom 1.1.1.3 E homoserine dehydrogenase
OPEFLCOJ_01838 9.8e-146 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
OPEFLCOJ_01839 1.5e-17 S Protein of unknown function (DUF4064)
OPEFLCOJ_01840 6.4e-287 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OPEFLCOJ_01841 5.7e-166 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
OPEFLCOJ_01842 3.1e-46 yhdT S Sodium pantothenate symporter
OPEFLCOJ_01843 6.5e-236 panF H Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OPEFLCOJ_01846 2.1e-171 corA P Mg2 transporter protein CorA family protein
OPEFLCOJ_01847 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
OPEFLCOJ_01848 3.3e-211 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
OPEFLCOJ_01849 5.4e-84
OPEFLCOJ_01850 1.1e-77 lytE CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
OPEFLCOJ_01851 1.4e-138 map 3.4.11.18 E Methionine aminopeptidase
OPEFLCOJ_01852 1.8e-99 bioY S Biotin biosynthesis protein
OPEFLCOJ_01853 6.7e-63 cueR K transcriptional
OPEFLCOJ_01854 1.5e-294 6.2.1.3, 6.2.1.34 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OPEFLCOJ_01855 0.0 aidB I Acyl-CoA dehydrogenase, middle domain
OPEFLCOJ_01856 5.3e-167 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OPEFLCOJ_01857 2.3e-153 aacC 2.3.1.81 V aminoglycoside
OPEFLCOJ_01858 1.7e-214 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OPEFLCOJ_01859 2.1e-70 yxiE T Belongs to the universal stress protein A family
OPEFLCOJ_01860 8.4e-28
OPEFLCOJ_01861 3.3e-69
OPEFLCOJ_01862 3e-228 yfkA S YfkB-like domain
OPEFLCOJ_01864 5.4e-286 K NB-ARC domain
OPEFLCOJ_01865 5e-201 gutB 1.1.1.14 E Dehydrogenase
OPEFLCOJ_01866 6.3e-91 gutA G MFS/sugar transport protein
OPEFLCOJ_01867 6.6e-90 gutA G MFS/sugar transport protein
OPEFLCOJ_01868 1.4e-181 ykvZ 5.1.1.1 K Transcriptional regulator
OPEFLCOJ_01869 5.1e-93 hxlB 4.1.2.43, 5.3.1.27 M arabinose-5-phosphate isomerase activity
OPEFLCOJ_01870 1.4e-147 ykrA S hydrolases of the HAD superfamily
OPEFLCOJ_01872 1e-147 yvaK 3.1.1.1 S BAAT / Acyl-CoA thioester hydrolase C terminal
OPEFLCOJ_01873 0.0 ubiE2 Q Methyltransferase domain
OPEFLCOJ_01874 7.2e-183 tas 1.1.1.65 C Aldo/keto reductase family
OPEFLCOJ_01875 1.8e-113 M Spore coat protein
OPEFLCOJ_01876 2.1e-137 I alpha/beta hydrolase fold
OPEFLCOJ_01877 1e-153 S Aldo/keto reductase family
OPEFLCOJ_01878 2.3e-99 1.5.1.38 S FMN reductase
OPEFLCOJ_01879 1.7e-248 yhaO L Calcineurin-like phosphoesterase superfamily domain
OPEFLCOJ_01880 0.0 L AAA domain
OPEFLCOJ_01881 2.1e-160 mmgB 1.1.1.157 I Dehydrogenase
OPEFLCOJ_01882 2.1e-247 yeeO V Mate efflux family protein
OPEFLCOJ_01884 2.7e-60 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
OPEFLCOJ_01885 9.3e-43 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
OPEFLCOJ_01886 3.4e-109 yhbD K Protein of unknown function (DUF4004)
OPEFLCOJ_01887 5.5e-225 yhdR 2.6.1.1 E Aminotransferase
OPEFLCOJ_01888 7.9e-98 proA_2 H Methyltransferase
OPEFLCOJ_01889 0.0 rafA 3.2.1.22 G Alpha-galactosidase
OPEFLCOJ_01890 3.2e-50 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
OPEFLCOJ_01891 2.6e-266 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OPEFLCOJ_01892 3.4e-146 ubiE Q Methyltransferase type 11
OPEFLCOJ_01893 7.8e-39
OPEFLCOJ_01894 7.7e-163 S Acetyl xylan esterase (AXE1)
OPEFLCOJ_01895 3.9e-153 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OPEFLCOJ_01896 1.7e-85 thiW S Thiamine-precursor transporter protein (ThiW)
OPEFLCOJ_01898 3.5e-271 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
OPEFLCOJ_01899 5.3e-254 pucI FH Permease for cytosine/purines, uracil, thiamine, allantoin
OPEFLCOJ_01900 2.1e-79 yjhE S Phage tail protein
OPEFLCOJ_01901 3.5e-260 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OPEFLCOJ_01902 2.8e-252 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
OPEFLCOJ_01903 1e-271 EGP Major facilitator Superfamily
OPEFLCOJ_01904 4e-113 K Bacterial regulatory proteins, tetR family
OPEFLCOJ_01905 1.3e-85 K Winged helix DNA-binding domain
OPEFLCOJ_01906 0.0 ydgH S drug exporters of the RND superfamily
OPEFLCOJ_01907 7.3e-149 hel M 5'-nucleotidase, lipoprotein e(P4)
OPEFLCOJ_01910 7.2e-214 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
OPEFLCOJ_01911 2.5e-17 I acyl-CoA dehydrogenase activity
OPEFLCOJ_01912 1.8e-12
OPEFLCOJ_01913 3.2e-225 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OPEFLCOJ_01914 2e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
OPEFLCOJ_01915 2.8e-290 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
OPEFLCOJ_01916 3.3e-197 galM 2.7.1.6, 5.1.3.3 G Converts alpha-aldose to the beta-anomer
OPEFLCOJ_01917 5.7e-183 K Transcriptional regulator
OPEFLCOJ_01918 5.1e-32 S Cold-inducible protein YdjO
OPEFLCOJ_01919 1.5e-14
OPEFLCOJ_01921 2.3e-164 cvfB S protein conserved in bacteria
OPEFLCOJ_01922 4e-71 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OPEFLCOJ_01923 2.1e-190 manA 5.3.1.8 G mannose-6-phosphate isomerase
OPEFLCOJ_01924 1.6e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OPEFLCOJ_01925 1.2e-274 yusP P Major facilitator superfamily
OPEFLCOJ_01926 8.3e-210 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
OPEFLCOJ_01927 5.2e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
OPEFLCOJ_01928 5.6e-124 gntR1 K transcriptional
OPEFLCOJ_01929 1.8e-181 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
OPEFLCOJ_01930 8.8e-228 NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
OPEFLCOJ_01931 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
OPEFLCOJ_01932 1.3e-166 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
OPEFLCOJ_01933 7.3e-115 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
OPEFLCOJ_01934 2.1e-205 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
OPEFLCOJ_01935 2.4e-124 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OPEFLCOJ_01936 2.2e-260 yfnA E amino acid
OPEFLCOJ_01937 2.8e-154 degV S protein conserved in bacteria
OPEFLCOJ_01939 3.6e-268 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
OPEFLCOJ_01940 3e-133 comFC S Phosphoribosyl transferase domain
OPEFLCOJ_01941 4.4e-70 yvyF S flagellar protein
OPEFLCOJ_01942 6.1e-39 flgM KNU Negative regulator of flagellin synthesis
OPEFLCOJ_01943 2.6e-77 flgN NOU FlgN protein
OPEFLCOJ_01944 8.4e-293 flgK N flagellar hook-associated protein
OPEFLCOJ_01945 5.2e-159 flgL N Belongs to the bacterial flagellin family
OPEFLCOJ_01946 6.4e-81 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
OPEFLCOJ_01947 1.6e-33 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
OPEFLCOJ_01948 1.3e-22 S Nucleotidyltransferase domain
OPEFLCOJ_01949 7.4e-100 secA U SEC-C motif
OPEFLCOJ_01950 1.8e-170 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OPEFLCOJ_01951 6.1e-97 K Glycerol-3-phosphate responsive antiterminator
OPEFLCOJ_01952 2.9e-112 sapB S MgtC SapB transporter
OPEFLCOJ_01953 2.2e-148 araL 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
OPEFLCOJ_01954 2.2e-145 G myo-inosose-2 dehydratase activity
OPEFLCOJ_01955 8e-244 EGP Sugar (and other) transporter
OPEFLCOJ_01957 3.9e-169 E COG1113 Gamma-aminobutyrate permease and related permeases
OPEFLCOJ_01958 0.0 ycbZ 3.4.21.53 O AAA domain
OPEFLCOJ_01960 2.9e-105 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
OPEFLCOJ_01962 6e-61 flaG N flagellar protein FlaG
OPEFLCOJ_01963 3.7e-224 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
OPEFLCOJ_01964 3.9e-69 fliS N flagellar protein FliS
OPEFLCOJ_01965 1.1e-56 fliT S bacterial-type flagellum organization
OPEFLCOJ_01966 2.7e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OPEFLCOJ_01967 3.5e-299 ggtA 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
OPEFLCOJ_01968 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
OPEFLCOJ_01969 2.5e-170 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
OPEFLCOJ_01970 6.1e-157 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
OPEFLCOJ_01971 1.6e-49 cccB C COG2010 Cytochrome c, mono- and diheme variants
OPEFLCOJ_01973 5.1e-122 ftsE D cell division ATP-binding protein FtsE
OPEFLCOJ_01974 1.4e-156 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
OPEFLCOJ_01975 2.6e-93 D peptidase
OPEFLCOJ_01976 9.3e-275 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OPEFLCOJ_01977 1.3e-248 metY 2.5.1.49 E O-acetylhomoserine
OPEFLCOJ_01978 3.7e-182 1.1.1.3 E homoserine dehydrogenase
OPEFLCOJ_01979 7.6e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
OPEFLCOJ_01980 4.4e-222 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OPEFLCOJ_01981 3.6e-166 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OPEFLCOJ_01982 1.8e-165 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OPEFLCOJ_01983 3.6e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
OPEFLCOJ_01984 1.1e-178 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
OPEFLCOJ_01985 2.1e-41 fdxA C 4Fe-4S binding domain
OPEFLCOJ_01986 4.5e-46 S Family of unknown function (DUF5316)
OPEFLCOJ_01987 1.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OPEFLCOJ_01988 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
OPEFLCOJ_01989 8.8e-262 hemY2 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
OPEFLCOJ_01990 4.7e-160 pstS P Phosphate
OPEFLCOJ_01991 7.5e-164 pstC P probably responsible for the translocation of the substrate across the membrane
OPEFLCOJ_01992 8.2e-157 pstA P Phosphate transport system permease
OPEFLCOJ_01993 7.2e-155 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
OPEFLCOJ_01994 2e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
OPEFLCOJ_01996 4.6e-174 M Glycosyltransferase like family 2
OPEFLCOJ_01997 0.0
OPEFLCOJ_01998 7.8e-58 P EamA-like transporter family
OPEFLCOJ_01999 8.6e-51 S EamA-like transporter family
OPEFLCOJ_02000 1.4e-118 yfbR S HD containing hydrolase-like enzyme
OPEFLCOJ_02001 2.4e-34 csbA S protein conserved in bacteria
OPEFLCOJ_02002 1.6e-09 S Uncharacterized conserved protein (DUF2164)
OPEFLCOJ_02003 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
OPEFLCOJ_02004 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
OPEFLCOJ_02005 2.8e-72 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
OPEFLCOJ_02006 4.7e-232 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OPEFLCOJ_02007 4.7e-232 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OPEFLCOJ_02008 2.7e-146 tagG GM Transport permease protein
OPEFLCOJ_02009 0.0 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
OPEFLCOJ_02010 1.6e-173 yvlB S Putative adhesin
OPEFLCOJ_02011 2.5e-32 yvlD S Membrane
OPEFLCOJ_02012 3e-248 L PFAM Transposase, IS4-like
OPEFLCOJ_02013 2.7e-174 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OPEFLCOJ_02014 1.6e-154 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OPEFLCOJ_02015 7.2e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
OPEFLCOJ_02016 1.5e-73 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
OPEFLCOJ_02017 8.2e-266 S COG0457 FOG TPR repeat
OPEFLCOJ_02018 1.3e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
OPEFLCOJ_02019 3e-86 yvcI 3.6.1.55 F Nudix hydrolase
OPEFLCOJ_02020 1.2e-168 rapZ S Displays ATPase and GTPase activities
OPEFLCOJ_02021 1e-179 ybhK S Required for morphogenesis under gluconeogenic growth conditions
OPEFLCOJ_02022 4e-173 whiA K May be required for sporulation
OPEFLCOJ_02023 4.3e-40 crh G Phosphocarrier protein Chr
OPEFLCOJ_02024 2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
OPEFLCOJ_02026 3.6e-147 S transposase or invertase
OPEFLCOJ_02027 2.2e-13 S transposase or invertase
OPEFLCOJ_02028 3e-262 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
OPEFLCOJ_02029 3.4e-29 sspB S spore protein
OPEFLCOJ_02030 6.9e-206 msmK P Belongs to the ABC transporter superfamily
OPEFLCOJ_02031 2.2e-165 lrp QT PucR C-terminal helix-turn-helix domain
OPEFLCOJ_02032 5.7e-230 HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)
OPEFLCOJ_02033 5e-270 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
OPEFLCOJ_02034 2.5e-211 yheC HJ YheC/D like ATP-grasp
OPEFLCOJ_02035 4.6e-252 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
OPEFLCOJ_02036 4.5e-208 yheB S Belongs to the UPF0754 family
OPEFLCOJ_02037 5.1e-54 yheA S Belongs to the UPF0342 family
OPEFLCOJ_02038 1.2e-160 yhaX S hydrolases of the HAD superfamily
OPEFLCOJ_02039 1.2e-138 yhaR 5.3.3.18 I enoyl-CoA hydratase
OPEFLCOJ_02040 2.9e-27 S YhzD-like protein
OPEFLCOJ_02041 6.2e-124 P Integral membrane protein TerC family
OPEFLCOJ_02043 1.6e-158 ycgR S permeases
OPEFLCOJ_02044 1e-164 ycgQ S membrane
OPEFLCOJ_02045 2.6e-241 yhaO L DNA repair exonuclease
OPEFLCOJ_02046 0.0 L AAA domain
OPEFLCOJ_02047 3.7e-179 yhaM L Shows a 3'-5' exoribonuclease activity
OPEFLCOJ_02048 3e-27 yhaL S Sporulation protein YhaL
OPEFLCOJ_02049 4.9e-154 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
OPEFLCOJ_02051 1.1e-53 yhaI S Protein of unknown function (DUF1878)
OPEFLCOJ_02052 1.5e-103 hpr K Negative regulator of protease production and sporulation
OPEFLCOJ_02053 1.2e-18 yhaH S YtxH-like protein
OPEFLCOJ_02054 1.1e-84 trpP S Tryptophan transporter TrpP
OPEFLCOJ_02055 1.4e-74 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
OPEFLCOJ_02056 1.9e-138 ecsA V transporter (ATP-binding protein)
OPEFLCOJ_02057 2e-222 ecsB U ABC transporter
OPEFLCOJ_02058 3.6e-224 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
OPEFLCOJ_02059 5.1e-238 yhfA C membrane
OPEFLCOJ_02060 4e-95 traP 1.14.99.57 S enzyme involved in biosynthesis of extracellular polysaccharides
OPEFLCOJ_02061 2.5e-200 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OPEFLCOJ_02062 8.5e-184 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
OPEFLCOJ_02063 4.7e-271 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
OPEFLCOJ_02064 6.4e-102 yhgD K Transcriptional regulator
OPEFLCOJ_02065 4.4e-222 yhgE S YhgE Pip N-terminal domain protein
OPEFLCOJ_02066 2.5e-183 arbF1 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
OPEFLCOJ_02067 3.6e-143 ydjF K DeoR C terminal sensor domain
OPEFLCOJ_02068 5.5e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
OPEFLCOJ_02069 1.5e-242 iolF EGP Major facilitator Superfamily
OPEFLCOJ_02070 6.2e-166 EG EamA-like transporter family
OPEFLCOJ_02071 3.7e-271 aldA 1.2.1.21, 1.2.1.22 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OPEFLCOJ_02072 1.1e-103 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
OPEFLCOJ_02073 3.6e-64 ytkA S YtkA-like
OPEFLCOJ_02074 3e-21 yhfH S YhfH-like protein
OPEFLCOJ_02075 3.2e-186 lplJ 6.3.1.20 H Lipoate-protein ligase
OPEFLCOJ_02076 3.2e-297 fadD 6.2.1.3 IQ Activates fatty acids by binding to coenzyme A
OPEFLCOJ_02077 2e-121 azlC E AzlC protein
OPEFLCOJ_02078 3.9e-42 azlD S branched-chain amino acid
OPEFLCOJ_02079 1.9e-220 yhfN 3.4.24.84 O Peptidase M48
OPEFLCOJ_02080 3.4e-09 S IDEAL
OPEFLCOJ_02081 1.6e-99 comK K Competence transcription factor
OPEFLCOJ_02082 1.7e-145 S Mitochondrial biogenesis AIM24
OPEFLCOJ_02084 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
OPEFLCOJ_02085 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
OPEFLCOJ_02086 4.2e-30 gerPF S Spore germination protein gerPA/gerPF
OPEFLCOJ_02087 3.6e-73 gerPE S Spore germination protein GerPE
OPEFLCOJ_02088 2e-25 gerPD S Spore germination protein
OPEFLCOJ_02089 2.7e-101 gerPC S Spore germination protein
OPEFLCOJ_02090 8.7e-31 gerPA S Spore germination protein
OPEFLCOJ_02091 1.9e-222 P Protein of unknown function (DUF418)
OPEFLCOJ_02092 2.4e-164 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
OPEFLCOJ_02093 5.1e-60 yisL S UPF0344 protein
OPEFLCOJ_02094 9.3e-106 yisN S Protein of unknown function (DUF2777)
OPEFLCOJ_02095 3.2e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OPEFLCOJ_02096 5.9e-160 yitS S protein conserved in bacteria
OPEFLCOJ_02097 5.7e-26 S Protein of unknown function (DUF3813)
OPEFLCOJ_02098 3.8e-156 yitU 3.1.3.104 S hydrolases of the HAD superfamily
OPEFLCOJ_02099 9.5e-52 yitW S metal-sulfur cluster biosynthetic enzyme
OPEFLCOJ_02100 1.2e-27 yjzC S YjzC-like protein
OPEFLCOJ_02101 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
OPEFLCOJ_02102 1.4e-144 5.1.3.2 GM ADP-glyceromanno-heptose 6-epimerase activity
OPEFLCOJ_02104 1.9e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OPEFLCOJ_02105 4.3e-236 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
OPEFLCOJ_02106 2.9e-153 yjaZ O Zn-dependent protease
OPEFLCOJ_02107 6.8e-195 oppD P Belongs to the ABC transporter superfamily
OPEFLCOJ_02108 7.5e-177 oppF P Belongs to the ABC transporter superfamily
OPEFLCOJ_02109 4e-173 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OPEFLCOJ_02110 5.9e-134 oppC EP binding-protein-dependent transport systems inner membrane component
OPEFLCOJ_02111 0.0 oppA1 E COG0747 ABC-type dipeptide transport system, periplasmic component
OPEFLCOJ_02112 5.9e-148 yjbA S Belongs to the UPF0736 family
OPEFLCOJ_02113 2.3e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
OPEFLCOJ_02115 4.2e-45 S Domain of unknown function (DUF3899)
OPEFLCOJ_02116 0.0 dppE_1 E ABC transporter substrate-binding protein
OPEFLCOJ_02117 2.4e-154 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OPEFLCOJ_02118 9.7e-186 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OPEFLCOJ_02119 6.1e-199 oppD P Belongs to the ABC transporter superfamily
OPEFLCOJ_02120 9e-178 oppF E Belongs to the ABC transporter superfamily
OPEFLCOJ_02121 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
OPEFLCOJ_02122 1.4e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
OPEFLCOJ_02123 5.7e-241 yjbF S Competence protein
OPEFLCOJ_02124 1.3e-260 S PFAM Uncharacterised protein family UPF0236
OPEFLCOJ_02125 0.0 pepF E oligoendopeptidase F
OPEFLCOJ_02127 7e-161 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
OPEFLCOJ_02128 1.4e-74 yjbI S COG2346 Truncated hemoglobins
OPEFLCOJ_02131 2.3e-86 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
OPEFLCOJ_02132 3.9e-107 yjbK S protein conserved in bacteria
OPEFLCOJ_02133 1.2e-56 yjbL S Belongs to the UPF0738 family
OPEFLCOJ_02134 3.8e-122 yjbM 2.7.6.5 S GTP pyrophosphokinase
OPEFLCOJ_02135 1.7e-153 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OPEFLCOJ_02136 4.3e-166 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OPEFLCOJ_02137 1.4e-146 prpE 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
OPEFLCOJ_02138 3.9e-142 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
OPEFLCOJ_02141 1.2e-84 cotY S Spore coat protein
OPEFLCOJ_02142 8.4e-60 S Protein of unknown function (DUF1360)
OPEFLCOJ_02144 6.6e-81 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OPEFLCOJ_02145 1.5e-83 spoVAC S stage V sporulation protein AC
OPEFLCOJ_02146 3.4e-191 spoVAD I Stage V sporulation protein AD
OPEFLCOJ_02147 8.7e-57 spoVAE S stage V sporulation protein
OPEFLCOJ_02149 4.5e-39 spoVIF S Stage VI sporulation protein F
OPEFLCOJ_02151 3.8e-75 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OPEFLCOJ_02152 1.5e-94 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
OPEFLCOJ_02153 1.8e-141 yjcH P COG2382 Enterochelin esterase and related enzymes
OPEFLCOJ_02155 0.0 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
OPEFLCOJ_02156 1.1e-308 L Domain of unknown function (DUF4277)
OPEFLCOJ_02157 6.9e-53 K UTRA domain
OPEFLCOJ_02158 9e-45 1.2.5.3, 1.3.99.16 C 2 iron, 2 sulfur cluster binding
OPEFLCOJ_02159 8.3e-167 C HI0933-like protein
OPEFLCOJ_02160 7.9e-46 thcD 1.14.13.111, 1.18.1.3, 1.7.1.15 S BFD-like [2Fe-2S] binding domain
OPEFLCOJ_02161 4.5e-197 hcnC 1.4.99.5 E FAD dependent oxidoreductase
OPEFLCOJ_02162 1.3e-137 MA20_04265 P Bacterial extracellular solute-binding protein
OPEFLCOJ_02163 1.1e-120 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
OPEFLCOJ_02164 4.8e-91 MA20_04255 P ABC-type spermidine putrescine transport system, permease component I
OPEFLCOJ_02165 5.1e-89 E COG1177 ABC-type spermidine putrescine transport system, permease component II
OPEFLCOJ_02166 1.6e-228 L PFAM Transposase, IS4-like
OPEFLCOJ_02167 1.7e-35 L Transposase, IS4 family protein
OPEFLCOJ_02168 1.5e-43 L COG2963 Transposase and inactivated derivatives
OPEFLCOJ_02169 5.2e-134 L COG2801 Transposase and inactivated derivatives
OPEFLCOJ_02170 1.4e-216 L Transposase, IS4 family protein
OPEFLCOJ_02171 1.1e-308 L Domain of unknown function (DUF4277)
OPEFLCOJ_02177 7.1e-169 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
OPEFLCOJ_02178 2.4e-56
OPEFLCOJ_02179 5.4e-133 IQ Enoyl-(Acyl carrier protein) reductase
OPEFLCOJ_02180 2.5e-169 yhaQ S ABC transporter, ATP-binding protein
OPEFLCOJ_02181 3.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
OPEFLCOJ_02182 9.2e-261 pepC 3.4.22.40 E Papain family cysteine protease
OPEFLCOJ_02183 4.7e-194 EGP Major facilitator Superfamily
OPEFLCOJ_02186 0.0 pepF2 E COG1164 Oligoendopeptidase F
OPEFLCOJ_02187 2.5e-08 sidE D nuclear chromosome segregation
OPEFLCOJ_02188 9.2e-34 ykuS S Belongs to the UPF0180 family
OPEFLCOJ_02189 2.1e-25
OPEFLCOJ_02191 0.0 6.2.1.1, 6.2.1.16 I AMP-dependent synthetase
OPEFLCOJ_02192 7.9e-271 L RNA-directed DNA polymerase (reverse transcriptase)
OPEFLCOJ_02193 4.6e-94 ywrA P COG2059 Chromate transport protein ChrA
OPEFLCOJ_02194 3.9e-102 chrA P Chromate transporter
OPEFLCOJ_02195 9.4e-83 ywrC K Transcriptional regulator
OPEFLCOJ_02196 1.7e-232 EGP Uncharacterised MFS-type transporter YbfB
OPEFLCOJ_02197 5.9e-307 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
OPEFLCOJ_02198 1.6e-227 3.5.1.4, 6.3.5.6, 6.3.5.7 J Belongs to the amidase family
OPEFLCOJ_02199 4.1e-23 EGP Major facilitator Superfamily
OPEFLCOJ_02200 1.3e-42 EGP Major facilitator Superfamily
OPEFLCOJ_02202 5.8e-163 pocR K Sensory domain found in PocR
OPEFLCOJ_02203 1.3e-232 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OPEFLCOJ_02204 1.2e-213 yxjG 2.1.1.14 E Methionine synthase
OPEFLCOJ_02205 5e-44 esxA S Belongs to the WXG100 family
OPEFLCOJ_02206 2e-295 esaA S domain protein
OPEFLCOJ_02207 3.6e-191 esaA S domain protein
OPEFLCOJ_02208 8.1e-55 Q domain protein
OPEFLCOJ_02209 1e-270 L RNA-directed DNA polymerase (reverse transcriptase)
OPEFLCOJ_02210 6.7e-254 G Major facilitator Superfamily
OPEFLCOJ_02211 0.0 mapA 2.4.1.8 GH65 G Glycoside hydrolase, family 65
OPEFLCOJ_02212 1.9e-124 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
OPEFLCOJ_02213 2e-39 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
OPEFLCOJ_02214 8.7e-215 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
OPEFLCOJ_02215 6.5e-108 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
OPEFLCOJ_02217 1e-42
OPEFLCOJ_02218 3.7e-182 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
OPEFLCOJ_02219 4.1e-259 proP EGP Transporter
OPEFLCOJ_02220 4.5e-150 yihS 5.1.3.11, 5.3.1.9 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
OPEFLCOJ_02221 1.1e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OPEFLCOJ_02223 1.2e-45
OPEFLCOJ_02224 5.6e-138 tesE Q COG3971 2-keto-4-pentenoate hydratase
OPEFLCOJ_02225 1.9e-74 nsrR K Transcriptional regulator
OPEFLCOJ_02226 5.3e-215 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OPEFLCOJ_02227 1.5e-122 S membrane transporter protein
OPEFLCOJ_02228 1.7e-73 dps P Ferritin-like domain
OPEFLCOJ_02229 2.3e-184 mocA S Oxidoreductase
OPEFLCOJ_02230 3.1e-206 pilS 2.7.13.3 T Histidine kinase
OPEFLCOJ_02231 3.5e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OPEFLCOJ_02232 3.8e-84
OPEFLCOJ_02233 4.7e-143 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
OPEFLCOJ_02234 2.1e-28 sspD S small acid-soluble spore protein
OPEFLCOJ_02235 7.3e-19 S Stage 0 Sporulation Regulatory protein
OPEFLCOJ_02237 8.7e-290 kinE 2.7.13.3 T Histidine kinase
OPEFLCOJ_02238 4.4e-85 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OPEFLCOJ_02239 3.3e-71 XK27_09985 S Protein of unknown function (DUF1232)
OPEFLCOJ_02241 0.0 clpE O Belongs to the ClpA ClpB family
OPEFLCOJ_02242 4.3e-181 ykvI S membrane
OPEFLCOJ_02243 2.7e-106 S Abortive infection protein
OPEFLCOJ_02244 2.5e-26 ykvS S protein conserved in bacteria
OPEFLCOJ_02245 3.5e-27
OPEFLCOJ_02246 3.2e-40 ptsH G phosphocarrier protein HPr
OPEFLCOJ_02247 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OPEFLCOJ_02248 1.4e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OPEFLCOJ_02249 1.2e-157 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
OPEFLCOJ_02250 1.2e-213 patA 2.6.1.1 E Aminotransferase
OPEFLCOJ_02251 1.6e-163 cheV 2.7.13.3 T Chemotaxis protein CheV
OPEFLCOJ_02252 3.1e-86 ykyB S YkyB-like protein
OPEFLCOJ_02253 0.0 ydgH S drug exporters of the RND superfamily
OPEFLCOJ_02254 0.0 T Diguanylate cyclase
OPEFLCOJ_02255 2e-32
OPEFLCOJ_02256 5.5e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OPEFLCOJ_02257 3.4e-166 3.5.1.4 C Acetamidase
OPEFLCOJ_02258 5.8e-39 ykuJ S protein conserved in bacteria
OPEFLCOJ_02259 6.5e-78 ykuL S CBS domain
OPEFLCOJ_02260 1.2e-157 ccpC K Transcriptional regulator
OPEFLCOJ_02261 4.7e-78 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
OPEFLCOJ_02262 1.9e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
OPEFLCOJ_02263 1.8e-18 S YhfH-like protein
OPEFLCOJ_02264 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OPEFLCOJ_02265 6.8e-30 ykzG S Belongs to the UPF0356 family
OPEFLCOJ_02266 9.2e-206 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
OPEFLCOJ_02267 1.3e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
OPEFLCOJ_02268 6.8e-232 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OPEFLCOJ_02269 1.8e-259 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
OPEFLCOJ_02270 9.2e-34
OPEFLCOJ_02272 2.4e-278 speA 4.1.1.19 E Arginine
OPEFLCOJ_02273 7.8e-48 yktA S Belongs to the UPF0223 family
OPEFLCOJ_02274 6.2e-119 yktB S Belongs to the UPF0637 family
OPEFLCOJ_02275 3.1e-24
OPEFLCOJ_02276 1.9e-149 suhB 3.1.3.25 G Inositol monophosphatase
OPEFLCOJ_02277 6e-25 S Family of unknown function (DUF5325)
OPEFLCOJ_02278 0.0 typA T GTP-binding protein TypA
OPEFLCOJ_02279 1.2e-52 ylaH S YlaH-like protein
OPEFLCOJ_02280 5.6e-250 phoH T ATPase related to phosphate starvation-inducible protein PhoH
OPEFLCOJ_02281 2.6e-88 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OPEFLCOJ_02282 1.5e-43 ylaN S Belongs to the UPF0358 family
OPEFLCOJ_02283 2e-217 ftsW D Belongs to the SEDS family
OPEFLCOJ_02284 3.6e-174 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
OPEFLCOJ_02285 2.9e-165 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
OPEFLCOJ_02286 9.8e-205 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
OPEFLCOJ_02287 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OPEFLCOJ_02288 1.2e-114 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
OPEFLCOJ_02289 1.4e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
OPEFLCOJ_02290 3e-176 ctaG S cytochrome c oxidase
OPEFLCOJ_02291 7.4e-64 ylbA S YugN-like family
OPEFLCOJ_02292 3.6e-180 ylbC S protein with SCP PR1 domains
OPEFLCOJ_02293 4.5e-85 yiiD Q protein, possibly involved in aromatic compounds catabolism
OPEFLCOJ_02294 5.8e-70 ylbD S Putative coat protein
OPEFLCOJ_02295 1.4e-37 ylbE S YlbE-like protein
OPEFLCOJ_02296 8.6e-63
OPEFLCOJ_02298 2.5e-15
OPEFLCOJ_02299 1.3e-73 ylbF S Belongs to the UPF0342 family
OPEFLCOJ_02300 5.3e-46 ylbG S UPF0298 protein
OPEFLCOJ_02301 2e-67 S Methylthioribose kinase
OPEFLCOJ_02302 2e-106 rsmD 2.1.1.171 L Methyltransferase
OPEFLCOJ_02303 1.5e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OPEFLCOJ_02304 3.6e-219 ylbJ S Sporulation integral membrane protein YlbJ
OPEFLCOJ_02305 9e-139 ylbK S esterase of the alpha-beta hydrolase superfamily
OPEFLCOJ_02306 7.4e-189 ylbL T Belongs to the peptidase S16 family
OPEFLCOJ_02307 2.8e-246 ylbM S Belongs to the UPF0348 family
OPEFLCOJ_02308 7.7e-97 yceD S metal-binding, possibly nucleic acid-binding protein
OPEFLCOJ_02309 1e-26 rpmF J Belongs to the bacterial ribosomal protein bL32 family
OPEFLCOJ_02310 1.5e-81 rsfA S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
OPEFLCOJ_02311 8.1e-93 ylbP K n-acetyltransferase
OPEFLCOJ_02312 2.4e-161 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OPEFLCOJ_02313 0.0 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
OPEFLCOJ_02314 2e-79 mraZ K Belongs to the MraZ family
OPEFLCOJ_02315 2.3e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
OPEFLCOJ_02316 2.5e-51 ftsL D Essential cell division protein
OPEFLCOJ_02317 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
OPEFLCOJ_02318 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
OPEFLCOJ_02319 3.1e-278 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OPEFLCOJ_02320 1.7e-78 murF 6.3.2.10 M UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OPEFLCOJ_02321 4.9e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OPEFLCOJ_02322 2.5e-258 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OPEFLCOJ_02323 7.7e-189 spoVE D Belongs to the SEDS family
OPEFLCOJ_02324 3.5e-205 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OPEFLCOJ_02325 2.4e-120 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
OPEFLCOJ_02326 2e-220 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
OPEFLCOJ_02327 1.2e-189 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OPEFLCOJ_02328 6.3e-168 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
OPEFLCOJ_02329 3.5e-230 L PFAM Transposase, IS116 IS110 IS902
OPEFLCOJ_02330 4.5e-113 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OPEFLCOJ_02331 1.5e-138 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OPEFLCOJ_02332 1.9e-43 ylmC S sporulation protein
OPEFLCOJ_02333 1e-77 yocH CBM50 M 3D domain
OPEFLCOJ_02334 4e-159 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
OPEFLCOJ_02335 7.8e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OPEFLCOJ_02336 1.1e-64 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
OPEFLCOJ_02337 2.5e-40 yggT S membrane
OPEFLCOJ_02338 3.7e-145 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
OPEFLCOJ_02339 4.3e-65 divIVA D Cell division initiation protein
OPEFLCOJ_02340 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OPEFLCOJ_02342 5.4e-81 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OPEFLCOJ_02343 2.4e-175 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OPEFLCOJ_02344 4.5e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
OPEFLCOJ_02345 5.2e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
OPEFLCOJ_02346 1.1e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
OPEFLCOJ_02347 2.6e-213 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
OPEFLCOJ_02348 0.0 carB 6.3.5.5 F Belongs to the CarB family
OPEFLCOJ_02349 4.4e-146 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
OPEFLCOJ_02350 8.2e-168 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
OPEFLCOJ_02351 2.7e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
OPEFLCOJ_02352 2e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OPEFLCOJ_02353 1.7e-178 tnp4 L Transposase, Mutator family
OPEFLCOJ_02354 1.3e-170 S Nuclease-related domain
OPEFLCOJ_02355 1.6e-205 L Transposase IS4 family protein
OPEFLCOJ_02356 1.5e-166 araC1 K AraC-like ligand binding domain
OPEFLCOJ_02357 5.5e-283 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
OPEFLCOJ_02358 4.9e-41 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
OPEFLCOJ_02359 4.5e-196 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
OPEFLCOJ_02360 5.2e-161 rhaD 4.1.2.17, 4.1.2.19, 5.1.3.4 G Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
OPEFLCOJ_02361 3.2e-32 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C hydroxyacid-oxoacid transhydrogenase activity
OPEFLCOJ_02362 1.1e-74 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
OPEFLCOJ_02363 4.7e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OPEFLCOJ_02364 3.3e-226 EGP Major facilitator Superfamily
OPEFLCOJ_02365 5.3e-265 lmrB EGP the major facilitator superfamily
OPEFLCOJ_02366 8.4e-99 yxaF_1 K Transcriptional regulator
OPEFLCOJ_02367 2.5e-103 yyaR K Acetyltransferase (GNAT) domain
OPEFLCOJ_02368 3e-191 S AI-2E family transporter
OPEFLCOJ_02369 3.8e-159 S hydrolases of the HAD superfamily
OPEFLCOJ_02370 0.0 S FAD binding domain
OPEFLCOJ_02371 1.3e-92
OPEFLCOJ_02372 5.1e-151
OPEFLCOJ_02373 5.5e-86 V AAA domain, putative AbiEii toxin, Type IV TA system
OPEFLCOJ_02374 5.1e-262 yihP G MFS/sugar transport protein
OPEFLCOJ_02375 8.7e-158 pocR K Sensory domain found in PocR
OPEFLCOJ_02376 6.1e-81 gldA 1.1.1.6 C Dehydrogenase
OPEFLCOJ_02377 2.1e-75 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
OPEFLCOJ_02378 2.9e-150 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase DhaK, subunit
OPEFLCOJ_02379 1.3e-81 dhaL 2.7.1.121 S Dak2
OPEFLCOJ_02380 1.3e-47 dhaM 2.7.1.121 S PTS system fructose IIA component
OPEFLCOJ_02381 2.7e-184 dhaT 1.1.1.1, 1.1.1.202 C Iron-containing alcohol dehydrogenase
OPEFLCOJ_02383 2.7e-115 sodA 1.15.1.1 P Iron/manganese superoxide dismutases, alpha-hairpin domain
OPEFLCOJ_02384 2.8e-180 C 4Fe-4S single cluster domain
OPEFLCOJ_02386 3.4e-42 lrpC K AsnC family transcriptional regulator
OPEFLCOJ_02387 1.3e-97 purD 6.3.4.13 F phosphoribosylamine-glycine ligase activity
OPEFLCOJ_02388 5.2e-53
OPEFLCOJ_02390 1.5e-88 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
OPEFLCOJ_02391 2e-137 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
OPEFLCOJ_02392 3.1e-165 yocS S -transporter
OPEFLCOJ_02393 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
OPEFLCOJ_02394 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
OPEFLCOJ_02395 1.9e-153 yicC S stress-induced protein
OPEFLCOJ_02396 9.1e-47 ylzA S Belongs to the UPF0296 family
OPEFLCOJ_02397 1.3e-108 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
OPEFLCOJ_02398 7.6e-29 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
OPEFLCOJ_02399 5.1e-226 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OPEFLCOJ_02400 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OPEFLCOJ_02401 1e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
OPEFLCOJ_02402 1.2e-177 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OPEFLCOJ_02403 1.4e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OPEFLCOJ_02404 8.9e-136 stp 3.1.3.16 T phosphatase
OPEFLCOJ_02405 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
OPEFLCOJ_02406 4.8e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
OPEFLCOJ_02407 5.9e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
OPEFLCOJ_02408 2.3e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
OPEFLCOJ_02409 5e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
OPEFLCOJ_02410 6.5e-60 asp S protein conserved in bacteria
OPEFLCOJ_02411 5.9e-305 yloV S kinase related to dihydroxyacetone kinase
OPEFLCOJ_02412 1.6e-120 sdaAB 4.3.1.17 E L-serine dehydratase
OPEFLCOJ_02413 1.3e-154 sdaAA 4.3.1.17 E L-serine dehydratase
OPEFLCOJ_02414 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OPEFLCOJ_02415 7.4e-98 fapR 5.3.1.23 Q Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
OPEFLCOJ_02416 7.8e-208 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
OPEFLCOJ_02417 4.3e-164 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
OPEFLCOJ_02418 1.4e-128 IQ reductase
OPEFLCOJ_02419 3.7e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
OPEFLCOJ_02420 2.4e-133 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
OPEFLCOJ_02421 0.0 smc D Required for chromosome condensation and partitioning
OPEFLCOJ_02422 2.5e-178 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
OPEFLCOJ_02423 2.6e-52 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
OPEFLCOJ_02424 5.1e-243 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OPEFLCOJ_02425 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
OPEFLCOJ_02426 4.7e-35 ylqC S Belongs to the UPF0109 family
OPEFLCOJ_02427 3.2e-60 ylqD S YlqD protein
OPEFLCOJ_02428 2.4e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OPEFLCOJ_02429 2.2e-139 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
OPEFLCOJ_02430 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
OPEFLCOJ_02431 2.1e-102 lepB 3.4.21.89 U Belongs to the peptidase S26 family
OPEFLCOJ_02432 1.3e-156 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OPEFLCOJ_02433 4.8e-129 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OPEFLCOJ_02434 1.5e-217 CP_1081 D nuclear chromosome segregation
OPEFLCOJ_02435 2.4e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
OPEFLCOJ_02436 2.4e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
OPEFLCOJ_02437 2e-166 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OPEFLCOJ_02438 6.9e-164 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
OPEFLCOJ_02439 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OPEFLCOJ_02442 5.1e-170 xerC L tyrosine recombinase XerC
OPEFLCOJ_02443 2.5e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OPEFLCOJ_02444 5.1e-225 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OPEFLCOJ_02445 8.6e-134 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
OPEFLCOJ_02446 2.8e-61 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
OPEFLCOJ_02447 4e-75 flgC N Belongs to the flagella basal body rod proteins family
OPEFLCOJ_02448 9.9e-41 fliE N Flagellar hook-basal body complex protein FliE
OPEFLCOJ_02449 2.4e-247 fliF N The M ring may be actively involved in energy transduction
OPEFLCOJ_02450 2.7e-164 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
OPEFLCOJ_02451 4.3e-130 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
OPEFLCOJ_02452 2.8e-23 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
OPEFLCOJ_02453 2.1e-205 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
OPEFLCOJ_02454 8.1e-73 fliJ N Flagellar biosynthesis chaperone
OPEFLCOJ_02455 1.3e-47 ylxF S MgtE intracellular N domain
OPEFLCOJ_02456 0.0 fliK N Flagellar hook-length control
OPEFLCOJ_02457 1.3e-103 flgD N Required for flagellar hook formation. May act as a scaffolding protein
OPEFLCOJ_02458 4e-75 flg N Putative flagellar
OPEFLCOJ_02459 3.4e-135 flgG N Flagellar basal body rod
OPEFLCOJ_02460 9.3e-66 fliL N Controls the rotational direction of flagella during chemotaxis
OPEFLCOJ_02461 9.9e-183 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
OPEFLCOJ_02462 4.3e-195 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OPEFLCOJ_02463 3.2e-59 cheB 3.1.1.61, 3.5.1.44 T response regulator
OPEFLCOJ_02464 1.2e-115 fliZ N Flagellar biosynthesis protein, FliO
OPEFLCOJ_02465 2e-107 fliP N Plays a role in the flagellum-specific transport system
OPEFLCOJ_02466 1.5e-37 fliQ N Role in flagellar biosynthesis
OPEFLCOJ_02467 2.5e-133 fliR N Flagellar biosynthetic protein FliR
OPEFLCOJ_02468 3.4e-189 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OPEFLCOJ_02469 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OPEFLCOJ_02470 8.4e-207 flhF N Flagellar biosynthesis regulator FlhF
OPEFLCOJ_02471 3e-156 flhG D Belongs to the ParA family
OPEFLCOJ_02472 9.6e-118 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
OPEFLCOJ_02473 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
OPEFLCOJ_02474 1.4e-69 cheW NT COG0835 Chemotaxis signal transduction protein
OPEFLCOJ_02475 4e-113 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
OPEFLCOJ_02476 4.3e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
OPEFLCOJ_02477 1.8e-136 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OPEFLCOJ_02478 8e-86 ylxL
OPEFLCOJ_02479 6.2e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
OPEFLCOJ_02480 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OPEFLCOJ_02481 1.5e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
OPEFLCOJ_02482 5.3e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
OPEFLCOJ_02483 1.6e-148 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OPEFLCOJ_02484 2.9e-145 cdsA 2.7.7.41 S Belongs to the CDS family
OPEFLCOJ_02485 1.6e-213 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
OPEFLCOJ_02486 7.4e-236 rasP M zinc metalloprotease
OPEFLCOJ_02487 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
OPEFLCOJ_02488 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OPEFLCOJ_02489 9.2e-83 rimP S Required for maturation of 30S ribosomal subunits
OPEFLCOJ_02490 3.1e-223 nusA K Participates in both transcription termination and antitermination
OPEFLCOJ_02491 8.2e-45 ylxR K nucleic-acid-binding protein implicated in transcription termination
OPEFLCOJ_02492 2.9e-48 ylxQ J ribosomal protein
OPEFLCOJ_02493 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OPEFLCOJ_02494 1.1e-43 ylxP S protein conserved in bacteria
OPEFLCOJ_02495 3.2e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OPEFLCOJ_02496 5.4e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OPEFLCOJ_02497 3.8e-184 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
OPEFLCOJ_02498 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OPEFLCOJ_02499 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
OPEFLCOJ_02500 5.2e-209 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
OPEFLCOJ_02501 5.2e-234 pepR S Belongs to the peptidase M16 family
OPEFLCOJ_02502 6.2e-38 ymxH S YlmC YmxH family
OPEFLCOJ_02503 1.3e-190 dpaA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
OPEFLCOJ_02504 7.4e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
OPEFLCOJ_02505 9.6e-189 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OPEFLCOJ_02506 6.4e-224 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
OPEFLCOJ_02507 1.1e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OPEFLCOJ_02508 0.0 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OPEFLCOJ_02509 2e-132 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
OPEFLCOJ_02510 3.3e-35 S YlzJ-like protein
OPEFLCOJ_02511 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
OPEFLCOJ_02512 1.5e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
OPEFLCOJ_02513 7.8e-288 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
OPEFLCOJ_02514 2e-186 yufP S Belongs to the binding-protein-dependent transport system permease family
OPEFLCOJ_02515 2.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
OPEFLCOJ_02516 9.4e-239 ymfF S Peptidase M16
OPEFLCOJ_02517 3.1e-245 ymfH S zinc protease
OPEFLCOJ_02518 1e-145 1.1.1.100 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
OPEFLCOJ_02519 6.4e-41 ymfJ S Protein of unknown function (DUF3243)
OPEFLCOJ_02520 9.9e-146 ymfK S Protein of unknown function (DUF3388)
OPEFLCOJ_02521 6.5e-141 ymfM S protein conserved in bacteria
OPEFLCOJ_02522 1.6e-100 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OPEFLCOJ_02523 4e-226 cinA 3.5.1.42 S Belongs to the CinA family
OPEFLCOJ_02524 2.1e-191 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OPEFLCOJ_02525 2.5e-217 rny S Endoribonuclease that initiates mRNA decay
OPEFLCOJ_02526 6.5e-153 ymdB S protein conserved in bacteria
OPEFLCOJ_02527 3.3e-37 spoVS S Stage V sporulation protein S
OPEFLCOJ_02528 6e-171 yegQ O Peptidase U32
OPEFLCOJ_02529 3.1e-250 yegQ O COG0826 Collagenase and related proteases
OPEFLCOJ_02530 1.1e-250 E Amino acid permease
OPEFLCOJ_02531 0.0 KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
OPEFLCOJ_02532 2.8e-290 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
OPEFLCOJ_02533 1.4e-264 patA 2.6.1.11, 2.6.1.17, 2.6.1.82 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OPEFLCOJ_02534 6.8e-300 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OPEFLCOJ_02535 6.8e-48 ymcA 3.6.3.21 S Belongs to the UPF0342 family
OPEFLCOJ_02536 3.6e-99 cotE S Outer spore coat protein E (CotE)
OPEFLCOJ_02537 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OPEFLCOJ_02538 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OPEFLCOJ_02539 5.7e-37 yhjA S Excalibur calcium-binding domain
OPEFLCOJ_02541 2.7e-30 2.1.1.80, 3.1.1.61 S protein secretion by the type IV secretion system
OPEFLCOJ_02544 5.8e-194 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OPEFLCOJ_02545 1.2e-35 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
OPEFLCOJ_02547 4.2e-175 spoVK O stage V sporulation protein K
OPEFLCOJ_02548 5.1e-229 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OPEFLCOJ_02549 2.3e-245 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
OPEFLCOJ_02550 9.5e-169 polA 2.7.7.7 L 5'3' exonuclease
OPEFLCOJ_02552 7.9e-27 ypeQ S Zinc-finger
OPEFLCOJ_02553 1.2e-31 cspD K Cold-shock protein
OPEFLCOJ_02554 6e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
OPEFLCOJ_02555 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
OPEFLCOJ_02556 4.4e-83
OPEFLCOJ_02557 1.9e-118 ypgQ S phosphohydrolase
OPEFLCOJ_02558 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
OPEFLCOJ_02559 4.8e-154 ypgR C COG0694 Thioredoxin-like proteins and domains
OPEFLCOJ_02560 5.6e-74 yphP S Belongs to the UPF0403 family
OPEFLCOJ_02561 3.1e-104 ypjP S YpjP-like protein
OPEFLCOJ_02562 1.4e-155 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OPEFLCOJ_02563 1.8e-92 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OPEFLCOJ_02564 1.9e-110 hlyIII S protein, Hemolysin III
OPEFLCOJ_02565 6.8e-139 ypmR E COG2755 Lysophospholipase L1 and related esterases
OPEFLCOJ_02566 3.5e-97 ypmS S protein conserved in bacteria
OPEFLCOJ_02567 2.3e-270 rsmF 2.1.1.176, 2.1.1.178 J RNA-binding PUA-like domain of methyltransferase RsmF
OPEFLCOJ_02568 6e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OPEFLCOJ_02569 7.3e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
OPEFLCOJ_02570 8.8e-18 S Protein of unknown function (Tiny_TM_bacill)
OPEFLCOJ_02571 1.5e-205 NT CHASE3 domain
OPEFLCOJ_02572 3e-36 yozE S Belongs to the UPF0346 family
OPEFLCOJ_02573 1.3e-116 yodN
OPEFLCOJ_02574 3.7e-24 yozD S YozD-like protein
OPEFLCOJ_02576 6.9e-147 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
OPEFLCOJ_02577 3.6e-263 S PFAM Uncharacterised protein family UPF0236
OPEFLCOJ_02578 6.4e-279 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
OPEFLCOJ_02579 2.4e-69 ypoP K transcriptional
OPEFLCOJ_02580 6.5e-99 ykwD J protein with SCP PR1 domains
OPEFLCOJ_02581 4.2e-245 norM V Multidrug efflux pump
OPEFLCOJ_02583 1.3e-182 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OPEFLCOJ_02584 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
OPEFLCOJ_02585 9.2e-134 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
OPEFLCOJ_02586 6.3e-106 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
OPEFLCOJ_02588 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
OPEFLCOJ_02589 2.3e-104 K Transcriptional regulator
OPEFLCOJ_02590 5.4e-59 4.4.1.5 E lactoylglutathione lyase activity
OPEFLCOJ_02591 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
OPEFLCOJ_02592 1.8e-229 ymfD EGP Major facilitator Superfamily
OPEFLCOJ_02593 1.5e-121 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OPEFLCOJ_02594 1.2e-255 arlS 2.7.13.3 T Histidine kinase
OPEFLCOJ_02595 4.9e-81 yozR S COG0071 Molecular chaperone (small heat shock protein)
OPEFLCOJ_02596 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
OPEFLCOJ_02597 3.5e-209 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
OPEFLCOJ_02598 7.5e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
OPEFLCOJ_02599 5.9e-92 rok S Repressor of ComK
OPEFLCOJ_02600 2.2e-113 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
OPEFLCOJ_02602 4.2e-161 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
OPEFLCOJ_02603 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OPEFLCOJ_02604 1.3e-192 yceA S Belongs to the UPF0176 family
OPEFLCOJ_02605 8e-128 yoqW S Belongs to the SOS response-associated peptidase family
OPEFLCOJ_02606 1.6e-103 thiT S Proton-coupled thiamine transporter YuaJ
OPEFLCOJ_02607 3.1e-169 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
OPEFLCOJ_02608 2.1e-79 S Domain in cystathionine beta-synthase and other proteins.
OPEFLCOJ_02609 2.9e-303 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
OPEFLCOJ_02610 6.1e-103 yocH CBM50 M COG1388 FOG LysM repeat
OPEFLCOJ_02611 0.0 topB2 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OPEFLCOJ_02612 3.8e-254 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
OPEFLCOJ_02613 2.6e-112 E Lysine exporter protein LysE YggA
OPEFLCOJ_02614 1.1e-178 corA P Mg2 transporter protein
OPEFLCOJ_02615 3.3e-69 S CHY zinc finger
OPEFLCOJ_02616 1.3e-212 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
OPEFLCOJ_02617 8.1e-111 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
OPEFLCOJ_02618 2.4e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OPEFLCOJ_02619 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
OPEFLCOJ_02620 1.5e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OPEFLCOJ_02621 1.1e-127 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OPEFLCOJ_02622 6.6e-139 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
OPEFLCOJ_02623 2.3e-119 hisE 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
OPEFLCOJ_02624 5.9e-41 yedF O Belongs to the sulfur carrier protein TusA family
OPEFLCOJ_02625 1.4e-239 yedE S Sulphur transport
OPEFLCOJ_02626 7.2e-175 rarD S -transporter
OPEFLCOJ_02627 2.9e-219 ktrB P COG0168 Trk-type K transport systems, membrane components
OPEFLCOJ_02628 1.7e-122 P COG0569 K transport systems, NAD-binding component
OPEFLCOJ_02629 3e-136 ykrK S Domain of unknown function (DUF1836)
OPEFLCOJ_02630 1.1e-16
OPEFLCOJ_02631 2.3e-47 yxcD S Protein of unknown function (DUF2653)
OPEFLCOJ_02632 8.6e-218 yeaN P COG2807 Cyanate permease
OPEFLCOJ_02633 0.0 ubiB S ABC1 family
OPEFLCOJ_02634 2.3e-23 S ATP synthase, subunit b
OPEFLCOJ_02635 7.2e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OPEFLCOJ_02637 2.7e-31 cspB K Cold shock
OPEFLCOJ_02638 3.6e-117 folE 3.5.4.16 H GTP cyclohydrolase
OPEFLCOJ_02639 5.1e-165 trxB_2 1.8.1.9 C FAD dependent oxidoreductase
OPEFLCOJ_02640 1.8e-44 S Protein of unknown function (DUF1292)
OPEFLCOJ_02641 8.1e-48 yxiS
OPEFLCOJ_02642 0.0 bceB V ABC transporter (permease)
OPEFLCOJ_02643 3.6e-137 bceA V ABC transporter, ATP-binding protein
OPEFLCOJ_02644 1.9e-181 bceS 2.7.13.3 T Signal transduction histidine kinase
OPEFLCOJ_02645 4.3e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OPEFLCOJ_02646 9.3e-172 S Protein of unknown function (DUF1672)
OPEFLCOJ_02647 4.6e-115 S Protein of unknown function (DUF1672)
OPEFLCOJ_02649 1.1e-71 ybzH K Helix-turn-helix domain
OPEFLCOJ_02650 4.7e-200 ybcL EGP Major facilitator Superfamily
OPEFLCOJ_02651 5.7e-194 yxaB GM Polysaccharide pyruvyl transferase
OPEFLCOJ_02652 1.4e-15
OPEFLCOJ_02653 2.3e-238 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
OPEFLCOJ_02654 3.6e-202 yetN S Protein of unknown function (DUF3900)
OPEFLCOJ_02655 1.1e-150
OPEFLCOJ_02657 5.9e-239 ywoD EGP Major facilitator superfamily
OPEFLCOJ_02658 2.5e-52 iscA S Heme biosynthesis protein HemY
OPEFLCOJ_02659 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
OPEFLCOJ_02660 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
OPEFLCOJ_02661 9.4e-43 S Small, acid-soluble spore proteins, alpha/beta type
OPEFLCOJ_02662 2.2e-61 S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
OPEFLCOJ_02663 1.1e-111 M effector of murein hydrolase
OPEFLCOJ_02664 0.0 alkK IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OPEFLCOJ_02665 2.4e-107 M lytic transglycosylase activity
OPEFLCOJ_02666 1.4e-08 S membrane
OPEFLCOJ_02667 1.9e-18 sspP S Belongs to the SspP family
OPEFLCOJ_02668 2.2e-38
OPEFLCOJ_02669 2.4e-267 S PFAM Uncharacterised protein family UPF0236
OPEFLCOJ_02670 6.4e-240 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
OPEFLCOJ_02671 4.4e-18 sspO S Belongs to the SspO family
OPEFLCOJ_02672 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OPEFLCOJ_02674 1e-19 sspN S Small acid-soluble spore protein N family
OPEFLCOJ_02675 4.1e-31 tlp S Belongs to the Tlp family
OPEFLCOJ_02676 2.2e-75 yneP S thioesterase
OPEFLCOJ_02677 1.1e-52 yneQ
OPEFLCOJ_02678 3.7e-53 yneR S Belongs to the HesB IscA family
OPEFLCOJ_02679 9.6e-101 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
OPEFLCOJ_02680 1.9e-71 yccU S CoA-binding protein
OPEFLCOJ_02681 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
OPEFLCOJ_02682 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
OPEFLCOJ_02683 5.8e-143
OPEFLCOJ_02684 2.3e-229 yjjL G Major facilitator superfamily
OPEFLCOJ_02685 1.1e-147 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
OPEFLCOJ_02686 0.0 ppdK 2.7.3.13, 2.7.9.1 G Belongs to the PEP-utilizing enzyme family
OPEFLCOJ_02687 7.9e-69 E Glyoxalase
OPEFLCOJ_02692 1.3e-199 yrpB 1.13.12.16, 1.3.1.9 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
OPEFLCOJ_02693 3.6e-102 5.1.3.34 S oxidoreductase activity
OPEFLCOJ_02694 9.1e-95 sipT 3.4.21.89 U Belongs to the peptidase S26 family
OPEFLCOJ_02696 2.6e-197 leuB1 1.1.1.85 CE Isocitrate/isopropylmalate dehydrogenase
OPEFLCOJ_02697 1.4e-161 2.1.1.144, 2.1.1.197 S Methyltransferase domain
OPEFLCOJ_02698 2.1e-08
OPEFLCOJ_02701 7.2e-138 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
OPEFLCOJ_02702 5.9e-94 yvbK 3.1.3.25 K acetyltransferase
OPEFLCOJ_02703 1e-92 VPA1573 J acetyltransferase
OPEFLCOJ_02704 2.6e-68 MA20_02285 2.3.1.57 K Acetyltransferase (GNAT) family
OPEFLCOJ_02705 6.9e-253 L PFAM Transposase, IS4-like
OPEFLCOJ_02706 7.1e-77 3.6.1.55 F Belongs to the Nudix hydrolase family
OPEFLCOJ_02707 6.3e-49 F nucleoside 2-deoxyribosyltransferase
OPEFLCOJ_02708 2.7e-116 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OPEFLCOJ_02709 1.1e-67 Q methyltransferase
OPEFLCOJ_02710 5.4e-127 2.5.1.2 M transport
OPEFLCOJ_02711 2.4e-245 cytX F Permease for cytosine/purines, uracil, thiamine, allantoin
OPEFLCOJ_02712 9e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
OPEFLCOJ_02713 2.8e-137 IQ Enoyl-(Acyl carrier protein) reductase
OPEFLCOJ_02714 6.4e-124 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
OPEFLCOJ_02715 7.8e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
OPEFLCOJ_02716 2.8e-114 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
OPEFLCOJ_02717 3.4e-123 yflK S protein conserved in bacteria
OPEFLCOJ_02718 4.3e-42 S COG NOG14552 non supervised orthologous group
OPEFLCOJ_02719 2.6e-42
OPEFLCOJ_02721 2.7e-82 2.3.1.57 K Acetyltransferase (GNAT) domain
OPEFLCOJ_02722 4.8e-10
OPEFLCOJ_02723 1.2e-214 S Psort location CytoplasmicMembrane, score
OPEFLCOJ_02724 1.8e-121 yfiR K Bacterial regulatory proteins, tetR family
OPEFLCOJ_02725 2.9e-196 yfiS EGP Major facilitator Superfamily
OPEFLCOJ_02726 2.1e-137 thiX 2.7.1.50 P binding-protein-dependent transport systems inner membrane component
OPEFLCOJ_02727 9.4e-186 nrtA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
OPEFLCOJ_02728 6e-75 S Glyoxalase bleomycin resistance protein dioxygenase
OPEFLCOJ_02729 3.2e-144 yitD 4.4.1.19 S synthase
OPEFLCOJ_02730 3.7e-128 comB 3.1.3.71 H Belongs to the ComB family
OPEFLCOJ_02731 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OPEFLCOJ_02732 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
OPEFLCOJ_02733 7.4e-109
OPEFLCOJ_02734 1.1e-133 mta K transcriptional
OPEFLCOJ_02735 2.3e-270 dapE 3.5.1.16, 3.5.1.18 E Peptidase dimerisation domain
OPEFLCOJ_02736 1.1e-175 yjlA EG Putative multidrug resistance efflux transporter
OPEFLCOJ_02737 2e-188 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
OPEFLCOJ_02738 1.1e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
OPEFLCOJ_02739 7.4e-217 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OPEFLCOJ_02740 2.1e-260 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
OPEFLCOJ_02741 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
OPEFLCOJ_02742 2e-189 kefA M Mechanosensitive ion channel
OPEFLCOJ_02743 3e-192 S COG0491 Zn-dependent hydrolases, including glyoxylases
OPEFLCOJ_02744 4.1e-56 I SCP-2 sterol transfer family
OPEFLCOJ_02745 1.3e-170 nrdB 1.17.4.1 F Ribonucleotide reductase, small chain
OPEFLCOJ_02746 1.3e-16 nrdB 1.17.4.1 F Ribonucleotide reductase, small chain
OPEFLCOJ_02747 1.2e-103 S Appr-1'-p processing enzyme
OPEFLCOJ_02748 2e-25 sspH S small acid-soluble spore protein
OPEFLCOJ_02749 3.1e-136 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OPEFLCOJ_02750 1.1e-209 2.3.1.16, 2.3.1.9 I Belongs to the thiolase family
OPEFLCOJ_02751 4.5e-288 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OPEFLCOJ_02752 1.9e-62 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
OPEFLCOJ_02753 3.5e-193 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
OPEFLCOJ_02754 2.7e-145 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
OPEFLCOJ_02755 5.6e-156 pucR QT COG2508 Regulator of polyketide synthase expression
OPEFLCOJ_02756 2.7e-151 pbuX F Permease family
OPEFLCOJ_02757 2.9e-35 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 S OHCU decarboxylase
OPEFLCOJ_02758 1e-204 P FAD-NAD(P)-binding
OPEFLCOJ_02759 5e-36 uraH 3.5.2.17 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
OPEFLCOJ_02760 3.9e-150 S Sucrose-6F-phosphate phosphohydrolase
OPEFLCOJ_02761 2.7e-97 yozB S membrane
OPEFLCOJ_02762 2e-59
OPEFLCOJ_02763 1.4e-78 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OPEFLCOJ_02764 1.8e-181 ldh1 1.1.1.27 C Belongs to the LDH MDH superfamily
OPEFLCOJ_02765 2.9e-131 IQ Enoyl-(Acyl carrier protein) reductase
OPEFLCOJ_02766 3.6e-216 fsr P COG0477 Permeases of the major facilitator superfamily
OPEFLCOJ_02767 7.4e-79 sleB 3.5.1.28 M Cell wall
OPEFLCOJ_02768 2e-148 xth 3.1.11.2 L exodeoxyribonuclease III
OPEFLCOJ_02769 1.1e-156 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
OPEFLCOJ_02770 1.3e-284 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
OPEFLCOJ_02771 3.1e-193 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
OPEFLCOJ_02772 6.8e-212 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OPEFLCOJ_02773 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OPEFLCOJ_02774 4.8e-198 G Glycosyl hydrolases family 15
OPEFLCOJ_02776 3e-22 S YpzG-like protein
OPEFLCOJ_02777 2.5e-89 Q protein disulfide oxidoreductase activity
OPEFLCOJ_02778 1.8e-95 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
OPEFLCOJ_02779 7.4e-120 nudL L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
OPEFLCOJ_02780 1.5e-228 mntH P H( )-stimulated, divalent metal cation uptake system
OPEFLCOJ_02781 1.4e-75 dps P Ferritin-like domain
OPEFLCOJ_02782 1.6e-79 V VanZ like family
OPEFLCOJ_02783 1.5e-169 yhcI S ABC-2 family transporter protein
OPEFLCOJ_02784 8.2e-171 ydbJ V ABC transporter, ATP-binding protein
OPEFLCOJ_02785 6.3e-57
OPEFLCOJ_02786 5.3e-167 murB 1.3.1.98 M cell wall formation
OPEFLCOJ_02787 7e-92 S Protein of unknown function (DUF1189)
OPEFLCOJ_02788 2.4e-37 S Protein of unknown function (DUF1450)
OPEFLCOJ_02789 2.7e-271 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OPEFLCOJ_02790 1.6e-70 I MaoC like domain
OPEFLCOJ_02791 1.4e-80 I N-terminal half of MaoC dehydratase
OPEFLCOJ_02792 1.8e-156 IQ Enoyl-(Acyl carrier protein) reductase
OPEFLCOJ_02793 5.9e-263 dld 1.1.1.303, 1.1.1.4, 1.1.2.4 C Glycolate oxidase subunit
OPEFLCOJ_02795 4.2e-200 selU S tRNA 2-selenouridine synthase
OPEFLCOJ_02796 3.1e-195 selD 2.7.9.3 E Synthesizes selenophosphate from selenide and ATP
OPEFLCOJ_02797 6.5e-136 T Calcineurin-like phosphoesterase superfamily domain
OPEFLCOJ_02798 2.9e-193 yraQ S Predicted permease
OPEFLCOJ_02799 1.1e-231 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OPEFLCOJ_02800 6.5e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OPEFLCOJ_02801 6.4e-73 yjlC S Protein of unknown function (DUF1641)
OPEFLCOJ_02802 2.8e-221 yjlD 1.6.99.3 C NADH dehydrogenase
OPEFLCOJ_02803 2e-230 nrnB S phosphohydrolase (DHH superfamily)
OPEFLCOJ_02804 4e-127 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
OPEFLCOJ_02805 2.3e-130 yvpB NU protein conserved in bacteria
OPEFLCOJ_02806 1.1e-50 tnrA K transcriptional
OPEFLCOJ_02807 1.4e-109 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
OPEFLCOJ_02808 1.1e-23 S Virus attachment protein p12 family
OPEFLCOJ_02809 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
OPEFLCOJ_02810 1.3e-47 feoA P COG1918 Fe2 transport system protein A
OPEFLCOJ_02811 8.5e-226 dapL 2.6.1.83 E Aminotransferase
OPEFLCOJ_02812 3.4e-266 argH 4.3.2.1 E argininosuccinate lyase
OPEFLCOJ_02813 4.8e-232 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
OPEFLCOJ_02814 3.1e-178 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OPEFLCOJ_02815 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
OPEFLCOJ_02816 6e-210 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
OPEFLCOJ_02817 3e-226 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
OPEFLCOJ_02818 1.5e-141 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
OPEFLCOJ_02819 1.5e-233 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OPEFLCOJ_02820 1.9e-200 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OPEFLCOJ_02822 6.5e-81
OPEFLCOJ_02823 1.2e-154 yjqC P Catalase
OPEFLCOJ_02824 4e-86
OPEFLCOJ_02825 2.3e-30 cspD K Cold shock
OPEFLCOJ_02826 7.9e-260 L Transposase
OPEFLCOJ_02828 1e-173 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
OPEFLCOJ_02829 8.6e-284 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
OPEFLCOJ_02830 1.1e-106 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
OPEFLCOJ_02831 3.4e-74 yneK S Protein of unknown function (DUF2621)
OPEFLCOJ_02832 4.6e-77 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
OPEFLCOJ_02833 7.9e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
OPEFLCOJ_02834 9.9e-129 ccdA O cytochrome c biogenesis protein
OPEFLCOJ_02835 6.8e-28 yneF S UPF0154 protein
OPEFLCOJ_02836 4.2e-77 yneE S Sporulation inhibitor of replication protein sirA
OPEFLCOJ_02837 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OPEFLCOJ_02838 2.8e-32 ynzC S UPF0291 protein
OPEFLCOJ_02839 4e-116 yneB L resolvase
OPEFLCOJ_02840 1.6e-55 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
OPEFLCOJ_02841 3.1e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OPEFLCOJ_02842 4.4e-263 glnA 6.3.1.2 E glutamine synthetase
OPEFLCOJ_02843 1.5e-65 glnR K transcriptional
OPEFLCOJ_02844 0.0 S Dynamin family
OPEFLCOJ_02845 2.9e-33
OPEFLCOJ_02846 6.6e-140 f42a O prohibitin homologues
OPEFLCOJ_02847 1.4e-232 pbuX F xanthine
OPEFLCOJ_02848 2.1e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
OPEFLCOJ_02849 1.7e-298 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
OPEFLCOJ_02850 2.3e-220 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
OPEFLCOJ_02851 9e-47 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
OPEFLCOJ_02852 1.4e-101 ypsA S Belongs to the UPF0398 family
OPEFLCOJ_02853 8.3e-46 cotD S Inner spore coat protein D
OPEFLCOJ_02854 3.4e-252 yprB L RNase_H superfamily
OPEFLCOJ_02855 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
OPEFLCOJ_02856 4.2e-77 hspX O Belongs to the small heat shock protein (HSP20) family
OPEFLCOJ_02857 2.9e-71 yppG S YppG-like protein
OPEFLCOJ_02858 7e-62 yppE S Bacterial domain of unknown function (DUF1798)
OPEFLCOJ_02862 1.9e-112 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
OPEFLCOJ_02863 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
OPEFLCOJ_02864 2.6e-123 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OPEFLCOJ_02865 2.3e-130 dnaD L DNA replication protein DnaD
OPEFLCOJ_02866 6.5e-273 L RNA-directed DNA polymerase (reverse transcriptase)
OPEFLCOJ_02867 2.2e-262 asnS 6.1.1.22 J asparaginyl-tRNA
OPEFLCOJ_02868 1.7e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
OPEFLCOJ_02869 1.7e-78 ypmB S protein conserved in bacteria
OPEFLCOJ_02870 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
OPEFLCOJ_02871 7.9e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OPEFLCOJ_02872 3.5e-160 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OPEFLCOJ_02873 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
OPEFLCOJ_02874 3.4e-180 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
OPEFLCOJ_02875 1.7e-226 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
OPEFLCOJ_02876 1.7e-221 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
OPEFLCOJ_02877 3.3e-132 bshB1 S proteins, LmbE homologs
OPEFLCOJ_02878 1.5e-149 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
OPEFLCOJ_02879 4.4e-58 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
OPEFLCOJ_02880 4.1e-161 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
OPEFLCOJ_02881 3.1e-81 queT S QueT transporter
OPEFLCOJ_02882 2.4e-103 yugP S Zn-dependent protease
OPEFLCOJ_02883 6e-143 ypjB S sporulation protein
OPEFLCOJ_02884 4.3e-109 ypjA S membrane
OPEFLCOJ_02885 1.1e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
OPEFLCOJ_02886 1.2e-126 petB C COG1290 Cytochrome b subunit of the bc complex
OPEFLCOJ_02887 1e-98 qcrA C Menaquinol-cytochrome c reductase
OPEFLCOJ_02888 2e-85 ypiF S Protein of unknown function (DUF2487)
OPEFLCOJ_02889 1.7e-99 ypiB S Belongs to the UPF0302 family
OPEFLCOJ_02890 8.5e-240 S COG0457 FOG TPR repeat
OPEFLCOJ_02891 2.3e-240 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
OPEFLCOJ_02892 1.3e-204 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
OPEFLCOJ_02893 9.3e-211 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OPEFLCOJ_02894 2.9e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
OPEFLCOJ_02895 1.2e-205 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OPEFLCOJ_02896 1.2e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OPEFLCOJ_02897 4.9e-145 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
OPEFLCOJ_02898 2.9e-78 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
OPEFLCOJ_02899 1e-176 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
OPEFLCOJ_02900 6.4e-128 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
OPEFLCOJ_02901 7.8e-146 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
OPEFLCOJ_02902 2.8e-32 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
OPEFLCOJ_02903 3.9e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
OPEFLCOJ_02904 1.8e-278 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OPEFLCOJ_02905 1.2e-137 yphF
OPEFLCOJ_02906 3.3e-08 yphE S Protein of unknown function (DUF2768)
OPEFLCOJ_02907 7.8e-191 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
OPEFLCOJ_02908 4.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
OPEFLCOJ_02909 1.2e-18 yphA
OPEFLCOJ_02910 7.3e-14 S YpzI-like protein
OPEFLCOJ_02911 3.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
OPEFLCOJ_02912 1.2e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
OPEFLCOJ_02913 2.5e-118 ypfA M Flagellar protein YcgR
OPEFLCOJ_02914 2.9e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
OPEFLCOJ_02915 3.9e-150 sleB 3.5.1.28 M Spore cortex-lytic enzyme
OPEFLCOJ_02916 2e-126 prsW S Involved in the degradation of specific anti-sigma factors
OPEFLCOJ_02917 4.3e-191 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
OPEFLCOJ_02918 1.2e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
OPEFLCOJ_02919 2.7e-111 mecB NOT Negative regulator of genetic competence (MecA)
OPEFLCOJ_02920 2.4e-144 ypbG S Calcineurin-like phosphoesterase superfamily domain
OPEFLCOJ_02921 2.8e-32 cotJA S Spore coat associated protein JA (CotJA)
OPEFLCOJ_02922 9.5e-45 cotJB S CotJB protein
OPEFLCOJ_02923 2.3e-104 cotJC P Spore Coat
OPEFLCOJ_02924 2e-79 ypbF S Protein of unknown function (DUF2663)
OPEFLCOJ_02926 2.9e-102 ypbD S metal-dependent membrane protease
OPEFLCOJ_02927 4.1e-286 recQ 3.6.4.12 L DNA helicase
OPEFLCOJ_02928 3.4e-205 ypbB 5.1.3.1 S protein conserved in bacteria
OPEFLCOJ_02929 4.7e-41 fer C Ferredoxin
OPEFLCOJ_02930 4.3e-98 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
OPEFLCOJ_02931 2.5e-135 M COG0739 Membrane proteins related to metalloendopeptidases
OPEFLCOJ_02932 0.0 resE 2.7.13.3 T Histidine kinase
OPEFLCOJ_02933 3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OPEFLCOJ_02934 5.4e-228 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
OPEFLCOJ_02935 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
OPEFLCOJ_02936 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
OPEFLCOJ_02937 9.9e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
OPEFLCOJ_02938 6.4e-88 spmB S Spore maturation protein
OPEFLCOJ_02939 5.2e-96 spmA S Spore maturation protein
OPEFLCOJ_02940 1e-212 dacB 3.4.16.4 M Belongs to the peptidase S11 family
OPEFLCOJ_02941 1.5e-106 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OPEFLCOJ_02942 1.9e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OPEFLCOJ_02944 9e-62 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OPEFLCOJ_02945 1.4e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
OPEFLCOJ_02946 4.9e-271 spoVAF EG Stage V sporulation protein AF
OPEFLCOJ_02947 6.6e-107 spoVAEA S Stage V sporulation protein AE
OPEFLCOJ_02948 1.3e-67 spoVAB S Stage V sporulation protein AB
OPEFLCOJ_02949 2.8e-111 spoVAA S Stage V sporulation protein AA
OPEFLCOJ_02950 1.1e-133 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OPEFLCOJ_02951 2.3e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
OPEFLCOJ_02952 2.5e-56 spoIIAA T Belongs to the anti-sigma-factor antagonist family
OPEFLCOJ_02953 3.3e-214 dacF 3.4.16.4 M Belongs to the peptidase S11 family
OPEFLCOJ_02954 4e-167 xerD L recombinase XerD
OPEFLCOJ_02955 1.7e-34 S Protein of unknown function (DUF4227)
OPEFLCOJ_02956 1.6e-85 fur P Belongs to the Fur family
OPEFLCOJ_02957 8.2e-106 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
OPEFLCOJ_02958 4.3e-230 yqxK 3.6.4.12 L DNA helicase
OPEFLCOJ_02959 2.6e-100 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
OPEFLCOJ_02961 2.4e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
OPEFLCOJ_02963 9.4e-110 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
OPEFLCOJ_02964 4.8e-216 yaaN P Belongs to the TelA family
OPEFLCOJ_02965 3.1e-175 yqkD S COG1073 Hydrolases of the alpha beta superfamily
OPEFLCOJ_02966 1.6e-242 yaaH_2 M Glycoside Hydrolase Family
OPEFLCOJ_02967 2.7e-55 S YolD-like protein
OPEFLCOJ_02968 2e-241 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OPEFLCOJ_02969 6.1e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
OPEFLCOJ_02970 3.5e-230 L PFAM Transposase, IS116 IS110 IS902
OPEFLCOJ_02971 7.7e-141 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OPEFLCOJ_02972 2.2e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
OPEFLCOJ_02973 2.4e-294 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OPEFLCOJ_02974 6.5e-229 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OPEFLCOJ_02975 2.2e-79 cheW NT COG0835 Chemotaxis signal transduction protein
OPEFLCOJ_02976 1.7e-204 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
OPEFLCOJ_02977 1.7e-95 yqjB S protein conserved in bacteria
OPEFLCOJ_02978 9.3e-77 yqiW S Belongs to the UPF0403 family
OPEFLCOJ_02979 1.3e-165 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
OPEFLCOJ_02980 1.5e-204 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OPEFLCOJ_02981 8.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
OPEFLCOJ_02982 5.9e-188 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
OPEFLCOJ_02983 1.2e-263 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
OPEFLCOJ_02984 2.3e-209 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
OPEFLCOJ_02985 1.2e-306 bkdR 2.7.13.3 KT Transcriptional regulator
OPEFLCOJ_02986 1.2e-36 yqzF S Protein of unknown function (DUF2627)
OPEFLCOJ_02987 5.1e-136 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
OPEFLCOJ_02988 2.8e-140 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
OPEFLCOJ_02990 1.2e-241 rseP 3.4.21.116 M Stage IV sporulation protein B
OPEFLCOJ_02991 1.9e-295 recN L May be involved in recombinational repair of damaged DNA
OPEFLCOJ_02992 1.2e-79 argR K Regulates arginine biosynthesis genes
OPEFLCOJ_02993 1.1e-147 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
OPEFLCOJ_02994 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OPEFLCOJ_02995 3.3e-158 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
OPEFLCOJ_02996 3.1e-31 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
OPEFLCOJ_02997 8.4e-238 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
OPEFLCOJ_02998 1.6e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OPEFLCOJ_02999 1.6e-64 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OPEFLCOJ_03000 1.9e-68 yqhY S protein conserved in bacteria
OPEFLCOJ_03001 3.7e-257 accC 6.3.4.14, 6.3.4.6, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
OPEFLCOJ_03002 5.2e-81 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
OPEFLCOJ_03003 5.5e-79 spoIIIAH S SpoIIIAH-like protein
OPEFLCOJ_03004 2.5e-110 spoIIIAG S stage III sporulation protein AG
OPEFLCOJ_03005 1.1e-107 spoIIIAF S stage III sporulation protein AF
OPEFLCOJ_03006 3.4e-190 spoIIIAE S stage III sporulation protein AE
OPEFLCOJ_03007 1.7e-58 spoIIIAD S Stage III sporulation protein AD
OPEFLCOJ_03008 1.4e-27 spoIIIAC S stage III sporulation protein AC
OPEFLCOJ_03009 1.7e-85 spoIIIAB S Stage III sporulation protein
OPEFLCOJ_03010 1e-170 spoIIIAA S stage III sporulation protein AA
OPEFLCOJ_03011 1.1e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OPEFLCOJ_03012 1.2e-162 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
OPEFLCOJ_03013 3.2e-80 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
OPEFLCOJ_03014 2.4e-86 yqhR S Conserved membrane protein YqhR
OPEFLCOJ_03015 2e-166 yqhQ S Protein of unknown function (DUF1385)
OPEFLCOJ_03016 1.3e-10 yqhP
OPEFLCOJ_03017 8.2e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
OPEFLCOJ_03018 1.4e-170 1.13.12.16, 1.3.1.9 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
OPEFLCOJ_03019 2.3e-175 paaX K PaaX-like protein
OPEFLCOJ_03020 5.8e-222 paaJ 2.3.1.16, 2.3.1.174, 2.3.1.223, 2.3.1.9 I Belongs to the thiolase family
OPEFLCOJ_03021 1.6e-157 ditN 1.1.1.157, 1.1.1.35, 4.2.1.17, 5.1.2.3, 5.3.3.8 I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
OPEFLCOJ_03022 2e-291 aldA 1.2.1.3, 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
OPEFLCOJ_03023 2e-25 paaG 5.3.3.18 I Enoyl-CoA hydratase
OPEFLCOJ_03024 7.7e-97 ycgT 1.18.1.2, 1.19.1.1 C reductase
OPEFLCOJ_03026 0.0 nrdA 1.17.4.1 F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
OPEFLCOJ_03027 1e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
OPEFLCOJ_03028 7.7e-67 yqhL P COG0607 Rhodanese-related sulfurtransferase
OPEFLCOJ_03029 1.6e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OPEFLCOJ_03030 1.4e-253 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OPEFLCOJ_03031 1.4e-214 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
OPEFLCOJ_03032 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
OPEFLCOJ_03033 6.9e-155 yqhG S Bacterial protein YqhG of unknown function
OPEFLCOJ_03034 6.7e-10 yqzE S YqzE-like protein
OPEFLCOJ_03035 2.6e-100 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OPEFLCOJ_03036 6e-61 S ComG operon protein 7
OPEFLCOJ_03037 1.5e-83 comGF U COG4940 Competence protein ComGF
OPEFLCOJ_03039 2.7e-76 gspH NU COG2165 Type II secretory pathway, pseudopilin PulG
OPEFLCOJ_03040 5.3e-50 comGC U Required for transformation and DNA binding
OPEFLCOJ_03041 1.7e-176 comGB NU COG1459 Type II secretory pathway, component PulF
OPEFLCOJ_03042 1.3e-210 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OPEFLCOJ_03043 3.1e-130 K Helix-turn-helix domain
OPEFLCOJ_03044 5.7e-36 yqgY S Protein of unknown function (DUF2626)
OPEFLCOJ_03045 2.9e-124 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
OPEFLCOJ_03046 7.5e-22 yqgW S Protein of unknown function (DUF2759)
OPEFLCOJ_03047 8.4e-179 glcK 2.7.1.2 G Glucokinase
OPEFLCOJ_03048 4.5e-30 yqgQ S protein conserved in bacteria
OPEFLCOJ_03049 1.4e-206 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
OPEFLCOJ_03051 1.6e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
OPEFLCOJ_03052 1.2e-53 yqzD
OPEFLCOJ_03053 0.0 mrdA 3.4.16.4 M penicillin-binding protein
OPEFLCOJ_03054 1.4e-218 yqgE EGP Major facilitator superfamily
OPEFLCOJ_03055 4.8e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
OPEFLCOJ_03056 9.9e-55 fimV NU Tfp pilus assembly protein FimV
OPEFLCOJ_03057 7.3e-203 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OPEFLCOJ_03058 4.9e-113 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
OPEFLCOJ_03059 3.8e-75 zur P Belongs to the Fur family
OPEFLCOJ_03060 1.8e-140 znuB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
OPEFLCOJ_03061 2.9e-142 zurA P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
OPEFLCOJ_03062 1.3e-19 yqfT S Protein of unknown function (DUF2624)
OPEFLCOJ_03063 4.9e-124 usp CBM50 M protein conserved in bacteria
OPEFLCOJ_03064 6.6e-170 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
OPEFLCOJ_03065 2.7e-241 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
OPEFLCOJ_03068 5.8e-180 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OPEFLCOJ_03069 1.6e-210 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OPEFLCOJ_03070 1.2e-112 trmK 2.1.1.217 S SAM-dependent methyltransferase
OPEFLCOJ_03071 2.2e-63 cccA C Cytochrome C oxidase, cbb3-type, subunit III
OPEFLCOJ_03072 2.1e-86
OPEFLCOJ_03073 2e-203 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
OPEFLCOJ_03074 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
OPEFLCOJ_03075 1.8e-147 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
OPEFLCOJ_03076 4.5e-112 ccpN K CBS domain
OPEFLCOJ_03077 3.1e-144 recO L Involved in DNA repair and RecF pathway recombination
OPEFLCOJ_03078 3e-08 S YqzL-like protein
OPEFLCOJ_03079 1.9e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OPEFLCOJ_03080 3e-66 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
OPEFLCOJ_03081 9.3e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OPEFLCOJ_03082 0.0 yqfF S membrane-associated HD superfamily hydrolase
OPEFLCOJ_03083 5.2e-173 phoH T Phosphate starvation-inducible protein PhoH
OPEFLCOJ_03084 2e-227 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
OPEFLCOJ_03085 3.2e-46 yqfC S sporulation protein YqfC
OPEFLCOJ_03086 5.4e-72 yqeY S Yqey-like protein
OPEFLCOJ_03087 9.5e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
OPEFLCOJ_03088 2.2e-47 acyP 3.6.1.7 C Belongs to the acylphosphatase family
OPEFLCOJ_03089 3.3e-156 yqeW P COG1283 Na phosphate symporter
OPEFLCOJ_03090 4.6e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
OPEFLCOJ_03091 1.6e-137 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
OPEFLCOJ_03092 5.1e-173 prmA J Methylates ribosomal protein L11
OPEFLCOJ_03093 1.5e-206 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
OPEFLCOJ_03094 2.5e-309 dnaK O Heat shock 70 kDa protein
OPEFLCOJ_03095 1.9e-81 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OPEFLCOJ_03096 3.2e-189 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
OPEFLCOJ_03097 2.2e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
OPEFLCOJ_03098 3.5e-230 L PFAM Transposase, IS116 IS110 IS902
OPEFLCOJ_03099 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
OPEFLCOJ_03100 1.6e-224 spoIIP M stage II sporulation protein P
OPEFLCOJ_03101 1.7e-199 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
OPEFLCOJ_03102 2.6e-34 rpsT J Binds directly to 16S ribosomal RNA
OPEFLCOJ_03103 1.4e-187 holA 2.7.7.7 L DNA polymerase III delta subunit
OPEFLCOJ_03104 3.1e-07 S YqzM-like protein
OPEFLCOJ_03105 0.0 comEC S Competence protein ComEC
OPEFLCOJ_03106 6.5e-113 comEB 3.5.4.12 F COG2131 Deoxycytidylate deaminase
OPEFLCOJ_03107 4e-85 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
OPEFLCOJ_03108 2.6e-149 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OPEFLCOJ_03109 8.5e-147 cmoA S Methyltransferase domain
OPEFLCOJ_03110 2.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
OPEFLCOJ_03111 1.8e-101 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
OPEFLCOJ_03112 1e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OPEFLCOJ_03113 4.8e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
OPEFLCOJ_03114 3.1e-161 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OPEFLCOJ_03115 7e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
OPEFLCOJ_03116 2.6e-94 yqeG S hydrolase of the HAD superfamily
OPEFLCOJ_03117 2.7e-260 glcF C Glycolate oxidase
OPEFLCOJ_03118 3.6e-263 glcD 1.1.3.15 C Glycolate oxidase subunit
OPEFLCOJ_03119 6.7e-193 ysfB KT regulator
OPEFLCOJ_03120 1.9e-280 mco 1.16.3.3 Q multicopper oxidases
OPEFLCOJ_03121 1.8e-75 hsp18 O Belongs to the small heat shock protein (HSP20) family
OPEFLCOJ_03122 7.8e-67 perX S DsrE/DsrF-like family
OPEFLCOJ_03123 5.3e-39 O Glutaredoxin
OPEFLCOJ_03124 8.2e-55 P Rhodanese Homology Domain
OPEFLCOJ_03125 0.0 cdr P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
OPEFLCOJ_03126 2.5e-18 S Short C-terminal domain
OPEFLCOJ_03127 4.2e-236 mco 1.16.3.3 Q multicopper oxidases
OPEFLCOJ_03128 3.9e-75 hsp18 O Belongs to the small heat shock protein (HSP20) family
OPEFLCOJ_03129 5.4e-23 S Short C-terminal domain
OPEFLCOJ_03130 3.1e-107 CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OPEFLCOJ_03131 8.2e-116 S TPM domain
OPEFLCOJ_03132 4.7e-76 lemA S LemA family
OPEFLCOJ_03133 4.3e-59 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OPEFLCOJ_03134 8.8e-61 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OPEFLCOJ_03135 9.1e-119 S VIT family
OPEFLCOJ_03136 1.7e-152 czcD P COG1230 Co Zn Cd efflux system component
OPEFLCOJ_03137 4.2e-15 sda S Sporulation inhibitor A
OPEFLCOJ_03138 1.6e-94 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OPEFLCOJ_03139 2.1e-126 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OPEFLCOJ_03141 3.4e-291 ahpF O Alkyl hydroperoxide reductase
OPEFLCOJ_03142 2.9e-107 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
OPEFLCOJ_03144 5e-10 S YrhC-like protein
OPEFLCOJ_03145 2.5e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OPEFLCOJ_03146 1.2e-29 yrzA S Protein of unknown function (DUF2536)
OPEFLCOJ_03147 5.5e-59 yrrS S Protein of unknown function (DUF1510)
OPEFLCOJ_03148 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
OPEFLCOJ_03149 6.8e-113 udk 2.7.1.48 F Cytidine monophosphokinase
OPEFLCOJ_03150 1.1e-115 yrrM 2.1.1.104 S O-methyltransferase
OPEFLCOJ_03151 5.9e-205 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OPEFLCOJ_03152 1.5e-41 yrzB S Belongs to the UPF0473 family
OPEFLCOJ_03153 8.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OPEFLCOJ_03154 5.8e-45 yrzL S Belongs to the UPF0297 family
OPEFLCOJ_03155 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OPEFLCOJ_03156 8.2e-175 yrrI S AI-2E family transporter
OPEFLCOJ_03158 1.8e-29 yrzR
OPEFLCOJ_03159 3.8e-70 yndM S Protein of unknown function (DUF2512)
OPEFLCOJ_03160 1.3e-57 K helix_turn_helix ASNC type
OPEFLCOJ_03161 4.3e-61 pdh 1.4.1.20, 1.4.1.9 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
OPEFLCOJ_03163 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
OPEFLCOJ_03164 7.4e-126 S COG0457 FOG TPR repeat
OPEFLCOJ_03165 1.9e-222 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
OPEFLCOJ_03166 1.5e-211 iscS 2.8.1.7 E Cysteine desulfurase
OPEFLCOJ_03167 2.3e-72 cymR K Transcriptional regulator
OPEFLCOJ_03168 1.5e-26
OPEFLCOJ_03169 6.7e-136 IQ Short-chain dehydrogenase reductase sdr
OPEFLCOJ_03170 3e-237 cshA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
OPEFLCOJ_03171 3.1e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
OPEFLCOJ_03172 5.5e-162 ybaS 1.1.1.58 S Na -dependent transporter
OPEFLCOJ_03174 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OPEFLCOJ_03175 2e-249 hisS 6.1.1.21 J histidyl-tRNA synthetase
OPEFLCOJ_03177 6.3e-271 lytH 3.5.1.28, 6.1.1.12 M COG3103 SH3 domain protein
OPEFLCOJ_03178 0.0 yhcA5 EGP Major facilitator Superfamily
OPEFLCOJ_03179 1.2e-107 emrA V Barrel-sandwich domain of CusB or HlyD membrane-fusion
OPEFLCOJ_03180 1.7e-70 K helix_turn_helix multiple antibiotic resistance protein
OPEFLCOJ_03181 1e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
OPEFLCOJ_03182 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OPEFLCOJ_03183 9e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OPEFLCOJ_03184 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
OPEFLCOJ_03185 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OPEFLCOJ_03186 1.2e-54 yrzD S Post-transcriptional regulator
OPEFLCOJ_03187 4.5e-275 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OPEFLCOJ_03188 9.5e-110 yrbG S membrane
OPEFLCOJ_03189 1.4e-63 yrzE S Protein of unknown function (DUF3792)
OPEFLCOJ_03190 8.7e-51 yajC U Preprotein translocase subunit YajC
OPEFLCOJ_03191 5.3e-225 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
OPEFLCOJ_03192 2.2e-193 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OPEFLCOJ_03193 3.2e-27 yrzS S Protein of unknown function (DUF2905)
OPEFLCOJ_03194 6.2e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
OPEFLCOJ_03195 2.5e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
OPEFLCOJ_03196 1.6e-126 yebC K transcriptional regulatory protein
OPEFLCOJ_03197 1.4e-189 1.1.1.34, 2.7.1.89 M choline kinase involved in LPS biosynthesis
OPEFLCOJ_03198 8.8e-136 safA M spore coat assembly protein SafA
OPEFLCOJ_03199 1.1e-95 niaR S small molecule binding protein (contains 3H domain)
OPEFLCOJ_03200 1.1e-158 pheA 4.2.1.51 E Prephenate dehydratase
OPEFLCOJ_03201 1.2e-74 pheB 5.4.99.5 S Belongs to the UPF0735 family
OPEFLCOJ_03202 9.9e-244 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OPEFLCOJ_03203 3e-98 spo0B T Sporulation initiation phospho-transferase B, C-terminal
OPEFLCOJ_03204 1.1e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
OPEFLCOJ_03205 1.6e-52 ysxB J ribosomal protein
OPEFLCOJ_03206 1.7e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
OPEFLCOJ_03207 1.1e-278 rng J ribonuclease, Rne Rng family
OPEFLCOJ_03208 9.8e-163 spoIVFB S Stage IV sporulation protein
OPEFLCOJ_03209 1.5e-135 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
OPEFLCOJ_03210 1.7e-145 minD D Belongs to the ParA family
OPEFLCOJ_03211 2.6e-121 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
OPEFLCOJ_03212 2.4e-87 mreD M shape-determining protein
OPEFLCOJ_03213 4.4e-139 mreC M Involved in formation and maintenance of cell shape
OPEFLCOJ_03214 6.9e-184 mreB D Rod shape-determining protein MreB
OPEFLCOJ_03215 1.1e-121 radC E Belongs to the UPF0758 family
OPEFLCOJ_03216 1.3e-171 spoIIB
OPEFLCOJ_03217 4.2e-133 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
OPEFLCOJ_03218 4.2e-103
OPEFLCOJ_03219 1e-87 pilN NU PFAM Fimbrial assembly family protein
OPEFLCOJ_03220 2.1e-193 NU COG4972 Tfp pilus assembly protein, ATPase PilM
OPEFLCOJ_03221 2.1e-57 NU Prokaryotic N-terminal methylation motif
OPEFLCOJ_03222 1.9e-204 pilC NU type II secretion system
OPEFLCOJ_03223 6.9e-195 pilT NU twitching motility protein
OPEFLCOJ_03224 1.2e-294 pilB NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OPEFLCOJ_03225 1.8e-222 V G5
OPEFLCOJ_03226 3.9e-128 S PRC-barrel domain
OPEFLCOJ_03227 3.4e-199
OPEFLCOJ_03228 6.6e-232 NU Pilus assembly protein PilX
OPEFLCOJ_03229 4.8e-85
OPEFLCOJ_03231 3.5e-252 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
OPEFLCOJ_03232 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
OPEFLCOJ_03233 9.5e-26
OPEFLCOJ_03234 1.6e-227 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OPEFLCOJ_03235 6.8e-198 spoVID M stage VI sporulation protein D
OPEFLCOJ_03236 7.8e-249 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
OPEFLCOJ_03237 7.1e-186 hemB 4.2.1.24 H Belongs to the ALAD family
OPEFLCOJ_03238 2.4e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
OPEFLCOJ_03239 4.9e-168 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
OPEFLCOJ_03240 7.7e-149 hemX O cytochrome C
OPEFLCOJ_03241 1.2e-241 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OPEFLCOJ_03242 4.5e-88 ysxD
OPEFLCOJ_03243 4.4e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
OPEFLCOJ_03244 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OPEFLCOJ_03245 2.2e-309 lonB 3.4.21.53 LO Belongs to the peptidase S16 family
OPEFLCOJ_03246 1.7e-235 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OPEFLCOJ_03247 2.1e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
OPEFLCOJ_03248 1.6e-185 S chaperone-mediated protein folding
OPEFLCOJ_03249 1.4e-72 S Protein of unknown function (DUF2512)
OPEFLCOJ_03250 3.4e-46
OPEFLCOJ_03252 2.8e-93 ysnB S Phosphoesterase
OPEFLCOJ_03253 1.6e-106 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OPEFLCOJ_03254 7.8e-191 gerM S COG5401 Spore germination protein
OPEFLCOJ_03255 1.1e-13
OPEFLCOJ_03256 5.8e-46 M Spore coat protein
OPEFLCOJ_03257 3e-220 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
OPEFLCOJ_03258 1.6e-61 yraF M Spore coat protein
OPEFLCOJ_03259 1.3e-31 yraG S Spore Coat Protein
OPEFLCOJ_03260 6.2e-151 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
OPEFLCOJ_03261 2.7e-79 ysmB 2.4.2.28 K transcriptional
OPEFLCOJ_03262 1.4e-92 S GDYXXLXY protein
OPEFLCOJ_03263 2.5e-195 S Predicted membrane protein (DUF2157)
OPEFLCOJ_03265 2.3e-31 gerE K Transcriptional regulator
OPEFLCOJ_03266 6.7e-89 ysmA S thioesterase
OPEFLCOJ_03267 1.3e-150 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
OPEFLCOJ_03268 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
OPEFLCOJ_03269 1.7e-105 sdhC C succinate dehydrogenase
OPEFLCOJ_03270 1.7e-81 yslB S Protein of unknown function (DUF2507)
OPEFLCOJ_03271 4.7e-219 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
OPEFLCOJ_03272 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
OPEFLCOJ_03273 5.1e-53 trxA O Belongs to the thioredoxin family
OPEFLCOJ_03274 1.1e-173 etfA C Electron transfer flavoprotein
OPEFLCOJ_03275 1.6e-127 etfB C Electron transfer flavoprotein
OPEFLCOJ_03276 1.2e-138 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
OPEFLCOJ_03277 1.6e-103 fadR K Transcriptional regulator
OPEFLCOJ_03278 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OPEFLCOJ_03279 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
OPEFLCOJ_03280 0.0 polX L COG1796 DNA polymerase IV (family X)
OPEFLCOJ_03281 4.9e-88 cvpA S membrane protein, required for colicin V production
OPEFLCOJ_03282 7.3e-46 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
OPEFLCOJ_03283 3.8e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OPEFLCOJ_03284 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
OPEFLCOJ_03285 3.9e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OPEFLCOJ_03288 1.9e-138 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OPEFLCOJ_03289 2.2e-31 sspI S Belongs to the SspI family
OPEFLCOJ_03290 2.6e-58
OPEFLCOJ_03291 7.9e-260 L Transposase
OPEFLCOJ_03292 7.9e-91 L COG3547 Transposase and inactivated derivatives
OPEFLCOJ_03293 2e-48 L COG3547 Transposase and inactivated derivatives
OPEFLCOJ_03294 8.7e-135 S Domain of unknown function (DUF4405)
OPEFLCOJ_03295 1.4e-41
OPEFLCOJ_03296 6.3e-57 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
OPEFLCOJ_03297 2.6e-121 M1-1017 S Protein of unknown function (DUF1129)
OPEFLCOJ_03298 1.8e-56 K Transcriptional regulator
OPEFLCOJ_03299 2.3e-11 S NADPH-dependent FMN reductase
OPEFLCOJ_03300 6.7e-127 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OPEFLCOJ_03301 1.5e-177 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OPEFLCOJ_03302 4.7e-102 yieF S NAD(P)H-dependent FMN reductase
OPEFLCOJ_03303 6.8e-123 mcpB3 NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
OPEFLCOJ_03304 1.2e-185 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
OPEFLCOJ_03305 5e-95 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OPEFLCOJ_03306 2.2e-268 M O-Antigen ligase
OPEFLCOJ_03307 7.3e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
OPEFLCOJ_03309 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OPEFLCOJ_03310 3.4e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
OPEFLCOJ_03311 4.5e-112 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OPEFLCOJ_03312 1.7e-219 G Transmembrane secretion effector
OPEFLCOJ_03313 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OPEFLCOJ_03314 4e-153 ytxC S YtxC-like family
OPEFLCOJ_03315 9e-178 dnaI L Primosomal protein DnaI
OPEFLCOJ_03316 2.8e-260 dnaB L Membrane attachment protein
OPEFLCOJ_03317 2.1e-79 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OPEFLCOJ_03318 4.9e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
OPEFLCOJ_03319 7.9e-103 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OPEFLCOJ_03320 1.6e-109 ytaF P Probably functions as a manganese efflux pump
OPEFLCOJ_03321 2.7e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
OPEFLCOJ_03322 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OPEFLCOJ_03323 6.8e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
OPEFLCOJ_03324 4e-245 icd 1.1.1.42 C isocitrate
OPEFLCOJ_03325 1.5e-208 citZ 2.3.3.1 C Belongs to the citrate synthase family
OPEFLCOJ_03326 1e-73 yeaL S Membrane
OPEFLCOJ_03327 1.3e-159 ytvI S sporulation integral membrane protein YtvI
OPEFLCOJ_03328 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
OPEFLCOJ_03329 2.4e-178 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
OPEFLCOJ_03330 1.1e-178 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
OPEFLCOJ_03331 4e-164 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OPEFLCOJ_03332 1.5e-228 ytsJ 1.1.1.38 C Malate dehydrogenase
OPEFLCOJ_03333 0.0 dnaE 2.7.7.7 L DNA polymerase
OPEFLCOJ_03334 1.6e-41 ytrH S Sporulation protein YtrH
OPEFLCOJ_03335 4.2e-89 ytrI
OPEFLCOJ_03336 1.4e-178 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
OPEFLCOJ_03337 1.9e-44 ytpI S YtpI-like protein
OPEFLCOJ_03338 8e-241 ytoI K transcriptional regulator containing CBS domains
OPEFLCOJ_03339 1.5e-129 ytkL S Belongs to the UPF0173 family
OPEFLCOJ_03340 1.5e-205 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
OPEFLCOJ_03341 5.2e-201 ald 1.4.1.1 E Belongs to the AlaDH PNT family
OPEFLCOJ_03342 5.6e-80 uspA T Belongs to the universal stress protein A family
OPEFLCOJ_03343 5e-156 S EcsC protein family
OPEFLCOJ_03344 2e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OPEFLCOJ_03345 2.9e-182 ytxK 2.1.1.72 L DNA methylase
OPEFLCOJ_03346 5.8e-91 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
OPEFLCOJ_03347 2.6e-69 ytfJ S Sporulation protein YtfJ
OPEFLCOJ_03348 7e-116 ytfI S Protein of unknown function (DUF2953)
OPEFLCOJ_03349 5.1e-90 yteJ S RDD family
OPEFLCOJ_03350 2.8e-185 sppA OU signal peptide peptidase SppA
OPEFLCOJ_03351 8.2e-309 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
OPEFLCOJ_03352 1.4e-27 sspB S spore protein
OPEFLCOJ_03353 5.6e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OPEFLCOJ_03354 3.9e-215 iscS2 2.8.1.7 E Cysteine desulfurase
OPEFLCOJ_03355 1.7e-307 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
OPEFLCOJ_03356 4.6e-117 yttP K Transcriptional regulator
OPEFLCOJ_03357 5.4e-86 ytsP 1.8.4.14 T GAF domain-containing protein
OPEFLCOJ_03358 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
OPEFLCOJ_03359 1.9e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OPEFLCOJ_03360 2e-71 K Helix-turn-helix XRE-family like proteins
OPEFLCOJ_03361 6.8e-184 putA E Proline dehydrogenase
OPEFLCOJ_03362 9.9e-299 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
OPEFLCOJ_03363 2.7e-247 prdR KT Transcriptional regulator
OPEFLCOJ_03364 6.1e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OPEFLCOJ_03365 2e-149 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OPEFLCOJ_03366 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
OPEFLCOJ_03367 4.4e-89 yrhD S Protein of unknown function (DUF1641)
OPEFLCOJ_03368 2.1e-193 moeB 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
OPEFLCOJ_03369 2.7e-85 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
OPEFLCOJ_03370 3e-34 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OPEFLCOJ_03371 3.9e-78 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
OPEFLCOJ_03372 3.4e-88 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
OPEFLCOJ_03373 7.1e-239 moeA 2.10.1.1 H molybdopterin
OPEFLCOJ_03374 1.9e-121 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
OPEFLCOJ_03375 8.1e-85 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
OPEFLCOJ_03376 5.4e-189 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OPEFLCOJ_03377 5.1e-133 modC 3.6.3.29 P ATPases associated with a variety of cellular activities
OPEFLCOJ_03378 1.1e-101 P COG4149 ABC-type molybdate transport system, permease component
OPEFLCOJ_03379 1.2e-122 modA P Molybdenum ABC transporter
OPEFLCOJ_03380 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
OPEFLCOJ_03381 5.2e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
OPEFLCOJ_03382 5.5e-118 acuB S Acetoin utilization protein AcuB
OPEFLCOJ_03383 5.4e-233 acuC BQ histone deacetylase
OPEFLCOJ_03384 1.3e-182 ccpA K catabolite control protein A
OPEFLCOJ_03385 3.8e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
OPEFLCOJ_03386 4.2e-33 XK27_07760 S COG4980 Gas vesicle protein
OPEFLCOJ_03387 5.6e-52 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
OPEFLCOJ_03388 8.8e-256 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
OPEFLCOJ_03389 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
OPEFLCOJ_03390 6.1e-69 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OPEFLCOJ_03391 6.7e-110 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
OPEFLCOJ_03392 3.4e-146 ytpQ S Belongs to the UPF0354 family
OPEFLCOJ_03393 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
OPEFLCOJ_03394 8e-205 rsbU 3.1.3.3 T response regulator
OPEFLCOJ_03395 7.3e-155 cheR 2.1.1.80 NT chemotaxis
OPEFLCOJ_03396 0.0 T PhoQ Sensor
OPEFLCOJ_03397 5.7e-92 EGP Transmembrane secretion effector
OPEFLCOJ_03398 6.6e-122 L PFAM Transposase, IS4-like
OPEFLCOJ_03399 9.1e-63 L PFAM Transposase, IS4-like
OPEFLCOJ_03400 5e-91 EGP Transmembrane secretion effector
OPEFLCOJ_03402 3.8e-33
OPEFLCOJ_03403 4.2e-92 yjjX F Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
OPEFLCOJ_03404 4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
OPEFLCOJ_03405 3.3e-52 ytzB S small secreted protein
OPEFLCOJ_03406 1.1e-171 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
OPEFLCOJ_03407 7.6e-134 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
OPEFLCOJ_03408 8.8e-59 ytzH S YtzH-like protein
OPEFLCOJ_03409 2.8e-156 ytmP 2.7.1.89 M Phosphotransferase
OPEFLCOJ_03410 4e-149 ytlQ
OPEFLCOJ_03411 2e-108 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
OPEFLCOJ_03413 2.3e-159 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
OPEFLCOJ_03414 1.8e-275 pepV 3.5.1.18 E Dipeptidase
OPEFLCOJ_03415 1.2e-32 ytzE K COG1349 Transcriptional regulators of sugar metabolism
OPEFLCOJ_03416 7e-287 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OPEFLCOJ_03417 4.1e-26 yteV S Sporulation protein Cse60
OPEFLCOJ_03418 1.7e-10
OPEFLCOJ_03420 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
OPEFLCOJ_03421 4.3e-185 yttB EGP Major facilitator Superfamily
OPEFLCOJ_03422 1.6e-42 ytzC S Protein of unknown function (DUF2524)
OPEFLCOJ_03423 5.2e-104 ytqB J Putative rRNA methylase
OPEFLCOJ_03425 1e-212 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
OPEFLCOJ_03426 2e-154 ytpA 3.1.1.5 I Alpha beta hydrolase
OPEFLCOJ_03427 2.5e-73 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OPEFLCOJ_03428 0.0 asnB 6.3.5.4 E Asparagine synthase
OPEFLCOJ_03429 5e-221 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OPEFLCOJ_03430 2.2e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
OPEFLCOJ_03431 4.8e-69 3.6.1.13, 3.6.1.55 L NTP pyrophosphohydrolases including oxidative damage repair enzymes
OPEFLCOJ_03432 1.1e-208 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
OPEFLCOJ_03433 1.3e-101 ywqN S NAD(P)H-dependent
OPEFLCOJ_03434 1.9e-302 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
OPEFLCOJ_03435 2.8e-185 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
OPEFLCOJ_03436 6.1e-140 ytlC P ABC transporter
OPEFLCOJ_03437 1.6e-127 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
OPEFLCOJ_03438 4.8e-84 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
OPEFLCOJ_03439 7.4e-39
OPEFLCOJ_03440 5.6e-77 dps P Belongs to the Dps family
OPEFLCOJ_03441 1.3e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
OPEFLCOJ_03443 6.3e-165 adcA P Belongs to the bacterial solute-binding protein 9 family
OPEFLCOJ_03444 1.6e-23 S Domain of Unknown Function (DUF1540)
OPEFLCOJ_03445 1.5e-208 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
OPEFLCOJ_03446 1.9e-275 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
OPEFLCOJ_03447 7.1e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OPEFLCOJ_03448 4.8e-148 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
OPEFLCOJ_03449 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
OPEFLCOJ_03450 7.7e-255 menF 5.4.4.2 HQ Isochorismate synthase
OPEFLCOJ_03451 3.8e-165 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
OPEFLCOJ_03461 3e-09
OPEFLCOJ_03467 5.1e-08
OPEFLCOJ_03468 1.6e-08
OPEFLCOJ_03472 1.7e-41
OPEFLCOJ_03473 4.3e-42 S COG NOG14552 non supervised orthologous group
OPEFLCOJ_03474 6e-232 wbbX GT2,GT4 M transferase activity, transferring glycosyl groups
OPEFLCOJ_03475 1.2e-56 V ATPases associated with a variety of cellular activities
OPEFLCOJ_03476 1.1e-37 S Protein of unknown function (DUF1430)
OPEFLCOJ_03477 0.0 L Domain of unknown function (DUF4277)
OPEFLCOJ_03478 8.9e-27 S Protein of unknown function (DUF1430)
OPEFLCOJ_03479 4.4e-17
OPEFLCOJ_03480 9e-151 EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
OPEFLCOJ_03481 5.5e-116 sapB S MgtC SapB transporter
OPEFLCOJ_03482 4.4e-165 S Protein of unknown function (DUF1646)
OPEFLCOJ_03483 7e-60 EGP Major facilitator Superfamily
OPEFLCOJ_03484 0.0 L Domain of unknown function (DUF4277)
OPEFLCOJ_03485 0.0 copA 3.6.3.54 P P-type ATPase
OPEFLCOJ_03486 8.9e-30 P Copper resistance protein CopZ
OPEFLCOJ_03487 8.4e-57 S protein conserved in bacteria
OPEFLCOJ_03488 2.4e-243 S PFAM Uncharacterised protein family UPF0236
OPEFLCOJ_03489 2.2e-259 L PFAM Transposase, IS4-like
OPEFLCOJ_03490 7.9e-30 csoR_2 S Metal-sensitive transcriptional repressor
OPEFLCOJ_03491 4.3e-68 lrpC K Transcriptional regulator
OPEFLCOJ_03492 1.2e-68 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OPEFLCOJ_03493 4e-223 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
OPEFLCOJ_03494 1.3e-27 yhjC S Protein of unknown function (DUF3311)
OPEFLCOJ_03495 1.4e-265 E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OPEFLCOJ_03498 3.1e-33 S Protein of unknown function (DUF2933)
OPEFLCOJ_03500 8.5e-249 T PhoQ Sensor
OPEFLCOJ_03501 1.5e-126 KT COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OPEFLCOJ_03502 4.9e-91 ydhK M Protein of unknown function (DUF1541)
OPEFLCOJ_03503 1.7e-99 VY92_08700 S Enoyl-(Acyl carrier protein) reductase
OPEFLCOJ_03504 1.3e-10 recN L Putative cell-wall binding lipoprotein
OPEFLCOJ_03505 4.1e-175 nodB1 G deacetylase
OPEFLCOJ_03509 7.3e-242 P Voltage gated chloride channel
OPEFLCOJ_03510 1.9e-49 P Rhodanese domain protein
OPEFLCOJ_03511 7.6e-16
OPEFLCOJ_03512 2.9e-129 yokF 3.1.31.1 L RNA catabolic process
OPEFLCOJ_03513 7.3e-71 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
OPEFLCOJ_03514 6.8e-262 S PFAM Uncharacterised protein family UPF0236
OPEFLCOJ_03515 1.7e-309 araB 2.7.1.12, 2.7.1.16, 2.7.1.17, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
OPEFLCOJ_03516 1.8e-254 araP EGP Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
OPEFLCOJ_03517 2.7e-131 araD 4.1.2.17, 4.1.2.19, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
OPEFLCOJ_03518 3.5e-282 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
OPEFLCOJ_03519 6.1e-213 araR K transcriptional
OPEFLCOJ_03520 1.5e-197 chvE G ABC transporter
OPEFLCOJ_03521 4e-284 araG 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
OPEFLCOJ_03522 3.5e-181 gguB G Belongs to the binding-protein-dependent transport system permease family
OPEFLCOJ_03523 4.8e-284 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
OPEFLCOJ_03524 0.0 araB 2.7.1.12, 2.7.1.16, 2.7.1.17, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
OPEFLCOJ_03525 2.7e-241 araR K transcriptional
OPEFLCOJ_03526 2e-214 NT chemotaxis protein
OPEFLCOJ_03527 5.3e-127 plsB 2.3.1.15 I Acyl-transferase
OPEFLCOJ_03528 2.7e-202 2.4.1.83 GT2 M Glycosyl transferase family 2
OPEFLCOJ_03529 2.1e-140 IQ Enoyl-(Acyl carrier protein) reductase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)