ORF_ID e_value Gene_name EC_number CAZy COGs Description
COOEGACM_00001 2.2e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
COOEGACM_00002 2.2e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
COOEGACM_00003 1.7e-34 yaaA S S4 domain protein YaaA
COOEGACM_00004 1.1e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
COOEGACM_00005 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
COOEGACM_00006 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
COOEGACM_00007 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
COOEGACM_00008 3.1e-77 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
COOEGACM_00009 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
COOEGACM_00010 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
COOEGACM_00011 2e-74 rplI J Binds to the 23S rRNA
COOEGACM_00012 5.3e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
COOEGACM_00013 4.5e-206 yttB EGP Major facilitator Superfamily
COOEGACM_00014 8.5e-59
COOEGACM_00015 2.8e-165 S Polyphosphate nucleotide phosphotransferase, PPK2 family
COOEGACM_00016 9.9e-100 K DNA-binding helix-turn-helix protein
COOEGACM_00018 3.1e-72 K helix_turn_helix multiple antibiotic resistance protein
COOEGACM_00019 7.2e-311 lmrA 3.6.3.44 V ABC transporter
COOEGACM_00021 3.1e-130 K response regulator
COOEGACM_00022 0.0 vicK 2.7.13.3 T Histidine kinase
COOEGACM_00023 1.9e-247 yycH S YycH protein
COOEGACM_00024 5.4e-150 yycI S YycH protein
COOEGACM_00025 1.2e-154 vicX 3.1.26.11 S domain protein
COOEGACM_00026 3.5e-217 htrA 3.4.21.107 O serine protease
COOEGACM_00027 5.9e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
COOEGACM_00028 2.1e-177 ABC-SBP S ABC transporter
COOEGACM_00029 4.7e-88 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
COOEGACM_00031 1.1e-95 S reductase
COOEGACM_00032 2.5e-225 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
COOEGACM_00033 7.5e-155 glcU U sugar transport
COOEGACM_00034 2.7e-148 E Glyoxalase-like domain
COOEGACM_00035 1e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
COOEGACM_00036 6.1e-260 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
COOEGACM_00037 1.1e-142 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
COOEGACM_00038 6.3e-128 V ABC transporter
COOEGACM_00039 5.6e-212 bacI V MacB-like periplasmic core domain
COOEGACM_00040 1.7e-29
COOEGACM_00041 4.3e-261 S Putative peptidoglycan binding domain
COOEGACM_00044 5.6e-250 L PFAM transposase, IS4 family protein
COOEGACM_00045 2.3e-183 2.7.13.3 T GHKL domain
COOEGACM_00046 4.2e-125 K LytTr DNA-binding domain
COOEGACM_00049 1e-240 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
COOEGACM_00050 3.1e-189 L PFAM Integrase catalytic region
COOEGACM_00052 1.9e-74 osmC O OsmC-like protein
COOEGACM_00053 1.5e-175 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COOEGACM_00054 1.5e-217 patA 2.6.1.1 E Aminotransferase
COOEGACM_00055 7.8e-32
COOEGACM_00056 0.0 clpL O associated with various cellular activities
COOEGACM_00057 1.7e-207 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
COOEGACM_00059 3.9e-107 wecD3 K PFAM GCN5-related N-acetyltransferase
COOEGACM_00060 2.8e-287 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COOEGACM_00061 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
COOEGACM_00062 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
COOEGACM_00063 2.3e-173 malR K Transcriptional regulator, LacI family
COOEGACM_00064 2.7e-216 phbA 2.3.1.9 I Belongs to the thiolase family
COOEGACM_00065 1.1e-256 malT G Major Facilitator
COOEGACM_00066 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
COOEGACM_00067 1e-119 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
COOEGACM_00068 1e-71
COOEGACM_00069 9.7e-88 2.7.6.5 T Region found in RelA / SpoT proteins
COOEGACM_00070 4.2e-113 K response regulator
COOEGACM_00071 1.5e-220 sptS 2.7.13.3 T Histidine kinase
COOEGACM_00072 1.1e-209 yfeO P Voltage gated chloride channel
COOEGACM_00073 9.6e-258 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
COOEGACM_00074 1.1e-135 puuD S peptidase C26
COOEGACM_00075 2.5e-166 yvgN C Aldo keto reductase
COOEGACM_00076 1.1e-250 L PFAM transposase, IS4 family protein
COOEGACM_00077 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
COOEGACM_00078 2.3e-87 hmpT S ECF-type riboflavin transporter, S component
COOEGACM_00079 2.4e-261 nox C NADH oxidase
COOEGACM_00080 2.5e-183 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
COOEGACM_00081 1.8e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
COOEGACM_00082 3.3e-85
COOEGACM_00083 4.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
COOEGACM_00085 1.1e-110 K Transcriptional regulator, TetR family
COOEGACM_00086 1e-69
COOEGACM_00087 2.4e-268 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
COOEGACM_00088 5.1e-268 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
COOEGACM_00089 1.9e-280 M domain protein
COOEGACM_00090 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
COOEGACM_00091 3.1e-267 G Major Facilitator
COOEGACM_00092 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
COOEGACM_00093 8.7e-209 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
COOEGACM_00094 5.5e-261 G Major Facilitator
COOEGACM_00095 1.7e-182 K Transcriptional regulator, LacI family
COOEGACM_00096 7.6e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
COOEGACM_00097 9.2e-101 nqr 1.5.1.36 S reductase
COOEGACM_00098 3.6e-198 XK27_09615 S reductase
COOEGACM_00099 5.5e-180 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
COOEGACM_00100 0.0 fhaB M Rib/alpha-like repeat
COOEGACM_00101 0.0 infB UW LPXTG-motif cell wall anchor domain protein
COOEGACM_00102 1.1e-250 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
COOEGACM_00103 4e-265 glnP P ABC transporter
COOEGACM_00104 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
COOEGACM_00106 8.5e-222 cycA E Amino acid permease
COOEGACM_00107 1e-218 nupG F Nucleoside transporter
COOEGACM_00108 2.7e-171 rihC 3.2.2.1 F Nucleoside
COOEGACM_00109 5e-162 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
COOEGACM_00110 4.5e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
COOEGACM_00111 7.4e-151 noc K Belongs to the ParB family
COOEGACM_00112 6.7e-139 soj D Sporulation initiation inhibitor
COOEGACM_00113 8.5e-154 spo0J K Belongs to the ParB family
COOEGACM_00114 5.4e-32 yyzM S Bacterial protein of unknown function (DUF951)
COOEGACM_00115 8.8e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
COOEGACM_00116 3.1e-136 XK27_01040 S Protein of unknown function (DUF1129)
COOEGACM_00117 9.8e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
COOEGACM_00118 2e-235 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
COOEGACM_00119 3.1e-237 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
COOEGACM_00120 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
COOEGACM_00121 4.8e-171 deoR K sugar-binding domain protein
COOEGACM_00122 2e-208 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
COOEGACM_00123 3.8e-125 K response regulator
COOEGACM_00124 3.7e-202 hpk31 2.7.13.3 T Histidine kinase
COOEGACM_00125 8.2e-136 azlC E AzlC protein
COOEGACM_00126 3.6e-52 azlD S branched-chain amino acid
COOEGACM_00127 2.2e-130 K LysR substrate binding domain
COOEGACM_00128 6.2e-171 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
COOEGACM_00129 8.6e-248 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
COOEGACM_00130 8.9e-170 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
COOEGACM_00131 6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
COOEGACM_00132 9.6e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
COOEGACM_00133 1.4e-113 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
COOEGACM_00134 1e-95 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
COOEGACM_00135 2.2e-229 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
COOEGACM_00136 4.9e-177 K AI-2E family transporter
COOEGACM_00137 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
COOEGACM_00138 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
COOEGACM_00139 4.5e-129 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
COOEGACM_00140 7.8e-263 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COOEGACM_00141 1.9e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
COOEGACM_00142 3.1e-212 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
COOEGACM_00143 5.2e-253 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
COOEGACM_00144 5.3e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
COOEGACM_00145 1.4e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COOEGACM_00146 1.9e-124 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COOEGACM_00147 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COOEGACM_00148 4.5e-277 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
COOEGACM_00149 2.9e-193 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
COOEGACM_00150 4.4e-103 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
COOEGACM_00151 2.8e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
COOEGACM_00152 2e-241 purD 6.3.4.13 F Belongs to the GARS family
COOEGACM_00153 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
COOEGACM_00154 2e-173
COOEGACM_00155 4.4e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
COOEGACM_00158 2.7e-66 XK27_01125 L PFAM IS66 Orf2 family protein
COOEGACM_00159 1.3e-295 L Transposase IS66 family
COOEGACM_00160 2.8e-238 L Transposase
COOEGACM_00161 7e-159 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
COOEGACM_00162 1.9e-132 3.6.1.13, 3.6.1.55 F NUDIX domain
COOEGACM_00163 3.1e-270 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
COOEGACM_00164 2.3e-101 pncA Q Isochorismatase family
COOEGACM_00165 1.4e-206 yegU O ADP-ribosylglycohydrolase
COOEGACM_00166 4.5e-255 F Belongs to the purine-cytosine permease (2.A.39) family
COOEGACM_00167 5.3e-164 G Belongs to the carbohydrate kinase PfkB family
COOEGACM_00168 7.4e-36 hxlR K regulation of RNA biosynthetic process
COOEGACM_00169 7.8e-263 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COOEGACM_00170 8.3e-238 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
COOEGACM_00171 1.6e-129 IQ Dehydrogenase reductase
COOEGACM_00172 1.1e-36
COOEGACM_00173 2.8e-114 ywnB S NAD(P)H-binding
COOEGACM_00174 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
COOEGACM_00175 2.8e-255 nhaC C Na H antiporter NhaC
COOEGACM_00176 2e-183 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
COOEGACM_00178 2e-97 ydeN S Serine hydrolase
COOEGACM_00179 4.5e-62 psiE S Phosphate-starvation-inducible E
COOEGACM_00180 6.5e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
COOEGACM_00182 7.7e-177 S Aldo keto reductase
COOEGACM_00183 3.6e-77 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
COOEGACM_00184 0.0 L Helicase C-terminal domain protein
COOEGACM_00186 6.3e-294 L Transposase
COOEGACM_00187 6.5e-246 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
COOEGACM_00188 2e-52 S Sugar efflux transporter for intercellular exchange
COOEGACM_00189 6.1e-125
COOEGACM_00190 1.4e-130 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
COOEGACM_00191 5e-311 cadA P P-type ATPase
COOEGACM_00192 1.7e-210 5.4.2.7 G Metalloenzyme superfamily
COOEGACM_00193 6.4e-294 L Transposase
COOEGACM_00194 5.2e-259 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COOEGACM_00196 3.7e-154 1.6.5.2 GM NAD(P)H-binding
COOEGACM_00197 2e-74 K Transcriptional regulator
COOEGACM_00198 3.9e-162 proX M ABC transporter, substrate-binding protein, QAT family
COOEGACM_00199 1.4e-108 proWZ P ABC transporter permease
COOEGACM_00200 3.3e-138 proV E ABC transporter, ATP-binding protein
COOEGACM_00201 1.3e-95 proW P ABC transporter, permease protein
COOEGACM_00202 2.4e-77 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
COOEGACM_00203 6e-252 clcA P chloride
COOEGACM_00204 5.7e-219 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
COOEGACM_00205 3.1e-103 metI P ABC transporter permease
COOEGACM_00206 1.9e-192 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
COOEGACM_00207 9.7e-155 metQ1 P Belongs to the nlpA lipoprotein family
COOEGACM_00208 2.6e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
COOEGACM_00209 3.1e-189 L PFAM Integrase catalytic region
COOEGACM_00210 2.2e-221 norA EGP Major facilitator Superfamily
COOEGACM_00211 8.6e-44 1.3.5.4 S FMN binding
COOEGACM_00212 5.4e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
COOEGACM_00213 8e-266 yfnA E amino acid
COOEGACM_00214 2.4e-256 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
COOEGACM_00216 1.8e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
COOEGACM_00217 0.0 helD 3.6.4.12 L DNA helicase
COOEGACM_00218 2.2e-81 ndk 2.7.4.6 F Belongs to the NDK family
COOEGACM_00219 1.2e-300 L Transposase
COOEGACM_00220 1.4e-181 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
COOEGACM_00221 2.9e-190 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
COOEGACM_00222 6e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
COOEGACM_00223 7e-226 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
COOEGACM_00224 8e-174
COOEGACM_00225 2.6e-129 cobB K SIR2 family
COOEGACM_00227 6.9e-161 yunF F Protein of unknown function DUF72
COOEGACM_00228 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
COOEGACM_00229 2.4e-155 tatD L hydrolase, TatD family
COOEGACM_00230 1.5e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
COOEGACM_00231 6.1e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
COOEGACM_00232 2.6e-36 veg S Biofilm formation stimulator VEG
COOEGACM_00233 3.1e-161 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
COOEGACM_00234 1.1e-164 znuA P Belongs to the bacterial solute-binding protein 9 family
COOEGACM_00235 1e-122 fhuC P ABC transporter
COOEGACM_00236 1.2e-127 znuB U ABC 3 transport family
COOEGACM_00237 6.9e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
COOEGACM_00238 1.7e-241 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
COOEGACM_00239 1.1e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
COOEGACM_00240 4.7e-49
COOEGACM_00241 3.9e-11 rarA L recombination factor protein RarA
COOEGACM_00242 8.1e-119 rarA L recombination factor protein RarA
COOEGACM_00243 1.2e-24 rarA L recombination factor protein RarA
COOEGACM_00244 1.8e-145 yxeH S hydrolase
COOEGACM_00245 3.6e-268 ywfO S HD domain protein
COOEGACM_00246 2.7e-154 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
COOEGACM_00247 9.6e-61 L PFAM transposase IS200-family protein
COOEGACM_00248 6.3e-229 L transposase, IS605 OrfB family
COOEGACM_00249 4.6e-67 ywiB S Domain of unknown function (DUF1934)
COOEGACM_00250 8.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
COOEGACM_00251 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
COOEGACM_00252 5.2e-237 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
COOEGACM_00253 4.6e-41 rpmE2 J Ribosomal protein L31
COOEGACM_00254 2.2e-235 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COOEGACM_00255 5.7e-166 S Alpha/beta hydrolase of unknown function (DUF915)
COOEGACM_00256 2.5e-124 srtA 3.4.22.70 M sortase family
COOEGACM_00257 4.4e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
COOEGACM_00258 2.9e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
COOEGACM_00259 7.8e-120 pgm3 G Belongs to the phosphoglycerate mutase family
COOEGACM_00260 2e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
COOEGACM_00261 2e-92 lemA S LemA family
COOEGACM_00262 1.5e-158 htpX O Belongs to the peptidase M48B family
COOEGACM_00263 4.4e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
COOEGACM_00264 1.4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
COOEGACM_00265 0.0 sprD D Domain of Unknown Function (DUF1542)
COOEGACM_00266 0.0 sprD D Domain of Unknown Function (DUF1542)
COOEGACM_00267 1.3e-295 L Transposase IS66 family
COOEGACM_00268 2.7e-66 XK27_01125 L PFAM IS66 Orf2 family protein
COOEGACM_00270 2.5e-164 glsA 3.5.1.2 E Belongs to the glutaminase family
COOEGACM_00271 1.2e-258 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COOEGACM_00272 1.7e-251 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
COOEGACM_00273 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COOEGACM_00274 1.5e-233 dltB M MBOAT, membrane-bound O-acyltransferase family
COOEGACM_00275 4.2e-294 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COOEGACM_00277 6.5e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
COOEGACM_00278 4.8e-210 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
COOEGACM_00279 1.6e-61 L Toxic component of a toxin-antitoxin (TA) module
COOEGACM_00280 8.9e-251 U Belongs to the purine-cytosine permease (2.A.39) family
COOEGACM_00281 8.9e-242 codA 3.5.4.1 F cytosine deaminase
COOEGACM_00282 5.8e-146 tesE Q hydratase
COOEGACM_00283 1.1e-113 S (CBS) domain
COOEGACM_00284 4.3e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
COOEGACM_00285 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
COOEGACM_00286 2.1e-39 yabO J S4 domain protein
COOEGACM_00287 5.6e-56 divIC D Septum formation initiator
COOEGACM_00288 9.8e-67 yabR J RNA binding
COOEGACM_00289 1.1e-264 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
COOEGACM_00290 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
COOEGACM_00291 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
COOEGACM_00292 1.5e-169 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
COOEGACM_00293 6.4e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
COOEGACM_00294 4.7e-293 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
COOEGACM_00295 5.5e-280 O Arylsulfotransferase (ASST)
COOEGACM_00299 3.1e-62 XK27_01125 L PFAM IS66 Orf2 family protein
COOEGACM_00300 9.2e-281 L Transposase IS66 family
COOEGACM_00302 5.4e-67 XK27_01125 L PFAM IS66 Orf2 family protein
COOEGACM_00303 2.1e-296 L Transposase IS66 family
COOEGACM_00304 3.1e-167 P CorA-like Mg2+ transporter protein
COOEGACM_00305 6.6e-98 wecD3 K PFAM GCN5-related N-acetyltransferase
COOEGACM_00306 2.6e-203 cytX U Belongs to the purine-cytosine permease (2.A.39) family
COOEGACM_00307 4.3e-13
COOEGACM_00308 5.8e-79 S Domain of unknown function (DUF4767)
COOEGACM_00309 3.1e-195 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
COOEGACM_00310 1.9e-115 S Membrane
COOEGACM_00311 4.2e-124 O Zinc-dependent metalloprotease
COOEGACM_00312 7.4e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
COOEGACM_00313 1.9e-158 metQ_4 P Belongs to the nlpA lipoprotein family
COOEGACM_00314 0.0 UW LPXTG-motif cell wall anchor domain protein
COOEGACM_00315 9.2e-120 UW LPXTG-motif cell wall anchor domain protein
COOEGACM_00316 0.0 UW LPXTG-motif cell wall anchor domain protein
COOEGACM_00317 0.0 UW LPXTG-motif cell wall anchor domain protein
COOEGACM_00318 0.0 UW LPXTG-motif cell wall anchor domain protein
COOEGACM_00319 4.6e-181 S Phosphotransferase system, EIIC
COOEGACM_00320 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
COOEGACM_00321 4.3e-181
COOEGACM_00322 1.1e-64 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
COOEGACM_00323 1.6e-205 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
COOEGACM_00324 5.2e-159 K LysR substrate binding domain
COOEGACM_00325 1.1e-107 manA 5.3.1.8 G mannose-6-phosphate isomerase
COOEGACM_00326 1.2e-22 manA 5.3.1.8 G mannose-6-phosphate isomerase
COOEGACM_00327 4.4e-97 2.3.1.128 K acetyltransferase
COOEGACM_00328 5.8e-183
COOEGACM_00329 4.4e-17 K Transcriptional regulator, HxlR family
COOEGACM_00330 3e-262 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COOEGACM_00331 4e-223 P ammonium transporter
COOEGACM_00332 5.6e-97 ureI S AmiS/UreI family transporter
COOEGACM_00333 3.7e-48 ureA 3.5.1.5 E Urease, gamma subunit
COOEGACM_00334 2.1e-69 ureB 3.5.1.5 E Urease beta subunit
COOEGACM_00335 0.0 ureC 3.5.1.5 E Amidohydrolase family
COOEGACM_00336 8.6e-78 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
COOEGACM_00337 1.9e-132 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
COOEGACM_00338 3.6e-114 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
COOEGACM_00339 3.2e-166 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
COOEGACM_00340 8.2e-185 nikMN P PDGLE domain
COOEGACM_00341 6.5e-135 P Cobalt transport protein
COOEGACM_00342 8.6e-136 cbiO P ABC transporter
COOEGACM_00343 3.5e-134 K Transcriptional regulatory protein, C-terminal domain protein
COOEGACM_00344 1.6e-160 pstS P Phosphate
COOEGACM_00345 6.6e-154 pstC P probably responsible for the translocation of the substrate across the membrane
COOEGACM_00346 6.5e-154 pstA P Phosphate transport system permease protein PstA
COOEGACM_00347 1.1e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
COOEGACM_00348 3.9e-125 phoU P Plays a role in the regulation of phosphate uptake
COOEGACM_00349 1.2e-136
COOEGACM_00350 1.9e-242 ydaM M Glycosyl transferase
COOEGACM_00351 3.9e-220 G Glycosyl hydrolases family 8
COOEGACM_00352 2.5e-138 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
COOEGACM_00353 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
COOEGACM_00354 3.2e-237 ktrB P Potassium uptake protein
COOEGACM_00355 1.4e-116 ktrA P domain protein
COOEGACM_00356 1.9e-79 Q Methyltransferase
COOEGACM_00357 3.1e-189 L PFAM Integrase catalytic region
COOEGACM_00358 3e-232 mntH P H( )-stimulated, divalent metal cation uptake system
COOEGACM_00359 3.1e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
COOEGACM_00360 1.6e-171 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
COOEGACM_00361 1.1e-95 S NADPH-dependent FMN reductase
COOEGACM_00362 2.1e-180 MA20_14895 S Conserved hypothetical protein 698
COOEGACM_00363 1.1e-135 I alpha/beta hydrolase fold
COOEGACM_00364 6.3e-170 lsa S ABC transporter
COOEGACM_00365 7.4e-180 yfeX P Peroxidase
COOEGACM_00366 5.7e-275 arcD S C4-dicarboxylate anaerobic carrier
COOEGACM_00367 8.9e-256 ytjP 3.5.1.18 E Dipeptidase
COOEGACM_00368 5.3e-215 uhpT EGP Major facilitator Superfamily
COOEGACM_00369 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
COOEGACM_00370 3.5e-263 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COOEGACM_00371 3.8e-129 ponA V Beta-lactamase enzyme family
COOEGACM_00372 2.3e-221 dacA 3.4.16.4 M Belongs to the peptidase S11 family
COOEGACM_00373 6.7e-75
COOEGACM_00374 8.3e-201 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
COOEGACM_00375 3.4e-22
COOEGACM_00378 3.3e-261 S Uncharacterized protein conserved in bacteria (DUF2252)
COOEGACM_00379 1.9e-169 L transposase, IS605 OrfB family
COOEGACM_00380 5e-295 L PFAM plasmid pRiA4b ORF-3 family protein
COOEGACM_00381 1.3e-204 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
COOEGACM_00382 2.3e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
COOEGACM_00383 2.8e-157 mleR K LysR family
COOEGACM_00384 3.1e-303 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
COOEGACM_00385 1.1e-259 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
COOEGACM_00386 1.4e-267 frdC 1.3.5.4 C FAD binding domain
COOEGACM_00387 9.7e-132 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
COOEGACM_00388 1.2e-165 citP P Sodium:sulfate symporter transmembrane region
COOEGACM_00389 4.7e-126 citR K sugar-binding domain protein
COOEGACM_00390 7.9e-176 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
COOEGACM_00391 7.4e-149 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
COOEGACM_00392 8.5e-42 citD C Covalent carrier of the coenzyme of citrate lyase
COOEGACM_00393 1.1e-159 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
COOEGACM_00394 7.1e-273 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
COOEGACM_00395 3e-148 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
COOEGACM_00396 1.1e-112 ydjP I Alpha/beta hydrolase family
COOEGACM_00397 3.9e-159 mleR K LysR family
COOEGACM_00398 9.4e-253 yjjP S Putative threonine/serine exporter
COOEGACM_00399 2.8e-117 ung2 3.2.2.27 L Uracil-DNA glycosylase
COOEGACM_00400 3.7e-277 emrY EGP Major facilitator Superfamily
COOEGACM_00401 7.9e-185 I Alpha beta
COOEGACM_00402 2.2e-93 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
COOEGACM_00403 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
COOEGACM_00405 7.3e-158 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
COOEGACM_00406 1.1e-117 S Domain of unknown function (DUF4811)
COOEGACM_00407 1.1e-265 lmrB EGP Major facilitator Superfamily
COOEGACM_00408 5.2e-75 merR K MerR HTH family regulatory protein
COOEGACM_00409 7.2e-56
COOEGACM_00410 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
COOEGACM_00411 1.6e-219 S CAAX protease self-immunity
COOEGACM_00412 3.6e-109 glnP P ABC transporter permease
COOEGACM_00413 1e-108 gluC P ABC transporter permease
COOEGACM_00414 1.7e-151 glnH ET ABC transporter
COOEGACM_00415 1.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
COOEGACM_00416 5.5e-83 usp1 T Belongs to the universal stress protein A family
COOEGACM_00417 2.2e-109 S VIT family
COOEGACM_00418 5e-117 S membrane
COOEGACM_00419 1.7e-165 czcD P cation diffusion facilitator family transporter
COOEGACM_00420 1.6e-123 sirR K iron dependent repressor
COOEGACM_00421 1e-30 cspC K Cold shock protein
COOEGACM_00422 2.1e-129 thrE S Putative threonine/serine exporter
COOEGACM_00423 2.1e-82 S Threonine/Serine exporter, ThrE
COOEGACM_00424 8.8e-119 lssY 3.6.1.27 I phosphatase
COOEGACM_00425 1.3e-09 2.3.1.128 J Acetyltransferase (GNAT) domain
COOEGACM_00426 3.8e-276 lysP E amino acid
COOEGACM_00427 1.1e-113 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
COOEGACM_00433 5.6e-250 L PFAM transposase, IS4 family protein
COOEGACM_00434 2e-177 S Hydrolases of the alpha beta superfamily
COOEGACM_00435 2.1e-196 adhP 1.1.1.1 C alcohol dehydrogenase
COOEGACM_00436 4.4e-77 ctsR K Belongs to the CtsR family
COOEGACM_00437 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
COOEGACM_00438 1e-110 K Bacterial regulatory proteins, tetR family
COOEGACM_00439 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COOEGACM_00440 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COOEGACM_00441 3.7e-197 ykiI
COOEGACM_00442 4e-119 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
COOEGACM_00443 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
COOEGACM_00444 1.2e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
COOEGACM_00445 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
COOEGACM_00446 5.2e-259 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COOEGACM_00447 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
COOEGACM_00448 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
COOEGACM_00449 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
COOEGACM_00450 2.2e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
COOEGACM_00451 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
COOEGACM_00452 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
COOEGACM_00453 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
COOEGACM_00454 6.7e-111 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
COOEGACM_00455 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
COOEGACM_00456 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
COOEGACM_00457 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
COOEGACM_00458 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
COOEGACM_00459 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
COOEGACM_00460 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
COOEGACM_00461 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
COOEGACM_00462 4.6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
COOEGACM_00463 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
COOEGACM_00464 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
COOEGACM_00465 2.9e-24 rpmD J Ribosomal protein L30
COOEGACM_00466 8.9e-64 rplO J Binds to the 23S rRNA
COOEGACM_00467 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
COOEGACM_00468 3.1e-124 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
COOEGACM_00469 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
COOEGACM_00470 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
COOEGACM_00471 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
COOEGACM_00472 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
COOEGACM_00473 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COOEGACM_00474 1.1e-62 rplQ J Ribosomal protein L17
COOEGACM_00475 3.3e-144 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COOEGACM_00476 6e-152 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COOEGACM_00477 3.4e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COOEGACM_00478 6.5e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
COOEGACM_00479 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
COOEGACM_00480 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
COOEGACM_00481 2.1e-140 IQ reductase
COOEGACM_00482 1e-113 acmC 3.2.1.96 NU mannosyl-glycoprotein
COOEGACM_00483 4.6e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
COOEGACM_00484 1.6e-213 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
COOEGACM_00485 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
COOEGACM_00486 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
COOEGACM_00487 1.2e-202 camS S sex pheromone
COOEGACM_00488 3.5e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
COOEGACM_00489 5.9e-277 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
COOEGACM_00490 1.8e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
COOEGACM_00491 6.7e-187 yegS 2.7.1.107 G Lipid kinase
COOEGACM_00492 3.1e-259 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
COOEGACM_00493 1.7e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
COOEGACM_00494 1.3e-252 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COOEGACM_00495 5.1e-41 K transcriptional regulator
COOEGACM_00496 2.1e-58 K transcriptional regulator
COOEGACM_00497 1.3e-297 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
COOEGACM_00498 2.5e-36 copZ P PFAM Heavy metal transport detoxification protein
COOEGACM_00499 7e-98 dps P Belongs to the Dps family
COOEGACM_00500 1.4e-110 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
COOEGACM_00501 2.5e-15 K DNA-binding transcription factor activity
COOEGACM_00502 1e-167 L Plasmid pRiA4b ORF-3-like protein
COOEGACM_00504 6.3e-61 S Protein of unknown function (DUF3021)
COOEGACM_00505 1.4e-75 K LytTr DNA-binding domain
COOEGACM_00506 3.7e-146 cylB V ABC-2 type transporter
COOEGACM_00507 1.8e-153 cylA V ABC transporter
COOEGACM_00508 5.7e-52
COOEGACM_00509 0.0 XK27_08510 L Type III restriction protein res subunit
COOEGACM_00510 3.1e-189 L PFAM Integrase catalytic region
COOEGACM_00511 6.2e-49 S PFAM Archaeal ATPase
COOEGACM_00512 7.4e-26 S PFAM Archaeal ATPase
COOEGACM_00513 1.1e-68 S PFAM Archaeal ATPase
COOEGACM_00514 6.4e-87 3.6.4.12 S PD-(D/E)XK nuclease family transposase
COOEGACM_00515 3e-207 amtB P ammonium transporter
COOEGACM_00516 1.1e-250 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
COOEGACM_00517 5.4e-78 yvbK 3.1.3.25 K GNAT family
COOEGACM_00518 1.3e-39
COOEGACM_00519 1.4e-124 pnb C nitroreductase
COOEGACM_00520 7.5e-29 XK27_00915 C Luciferase-like monooxygenase
COOEGACM_00521 8.8e-73 XK27_00915 C Luciferase-like monooxygenase
COOEGACM_00522 1.1e-31 XK27_00915 C Luciferase-like monooxygenase
COOEGACM_00523 6.8e-154 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
COOEGACM_00524 1.4e-67 S Protein of unknown function (DUF3021)
COOEGACM_00525 3.5e-76 K LytTr DNA-binding domain
COOEGACM_00526 5.5e-21
COOEGACM_00527 6.1e-200 yhjX P Major Facilitator Superfamily
COOEGACM_00528 1.1e-119 ybhL S Belongs to the BI1 family
COOEGACM_00529 1.6e-79 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
COOEGACM_00530 1.2e-191 S Protein of unknown function (DUF3114)
COOEGACM_00531 1.4e-297 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
COOEGACM_00532 3.5e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
COOEGACM_00533 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
COOEGACM_00534 9.1e-62 S Domain of unknown function (DUF4828)
COOEGACM_00535 4.5e-191 mocA S Oxidoreductase
COOEGACM_00536 6.7e-232 yfmL L DEAD DEAH box helicase
COOEGACM_00538 4.4e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
COOEGACM_00539 1.5e-74 gtcA S Teichoic acid glycosylation protein
COOEGACM_00540 1.8e-78 fld C Flavodoxin
COOEGACM_00541 1.3e-167 map 3.4.11.18 E Methionine Aminopeptidase
COOEGACM_00542 5.1e-220 arcT 2.6.1.1 E Aminotransferase
COOEGACM_00543 1.7e-257 E Arginine ornithine antiporter
COOEGACM_00544 2.2e-279 yjeM E Amino Acid
COOEGACM_00545 1.8e-151 yihY S Belongs to the UPF0761 family
COOEGACM_00546 3.9e-34 S Protein of unknown function (DUF2922)
COOEGACM_00547 4.9e-31
COOEGACM_00548 2.5e-136 recX 2.4.1.337 GT4 S Regulatory protein RecX
COOEGACM_00549 9.6e-146 cps1D M Domain of unknown function (DUF4422)
COOEGACM_00550 3.5e-174 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
COOEGACM_00551 4.1e-121 rfbP 2.7.8.6 M Bacterial sugar transferase
COOEGACM_00552 0.0 2.7.7.6 M Peptidase family M23
COOEGACM_00553 0.0 G Peptidase_C39 like family
COOEGACM_00554 2.7e-25
COOEGACM_00556 3.1e-62 XK27_01125 L PFAM IS66 Orf2 family protein
COOEGACM_00557 9.2e-281 L Transposase IS66 family
COOEGACM_00558 1.6e-218 glf 5.4.99.9 M UDP-galactopyranose mutase
COOEGACM_00559 4.9e-244 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
COOEGACM_00560 2.3e-69 cps3F
COOEGACM_00561 2.2e-47 M biosynthesis protein
COOEGACM_00562 1.3e-139 rgpB GT2 M Glycosyltransferase, group 2 family protein
COOEGACM_00563 8.9e-123 M Domain of unknown function (DUF4422)
COOEGACM_00564 7.1e-139 S Glycosyltransferase like family
COOEGACM_00565 8.2e-23
COOEGACM_00566 1.5e-90 S Bacterial membrane protein, YfhO
COOEGACM_00567 3.8e-32
COOEGACM_00568 3.1e-189 L PFAM Integrase catalytic region
COOEGACM_00570 0.0 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
COOEGACM_00571 8.6e-159 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
COOEGACM_00572 4.6e-108 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
COOEGACM_00573 6e-199 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
COOEGACM_00574 5e-156 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
COOEGACM_00575 6.6e-291 G Peptidase_C39 like family
COOEGACM_00576 1.3e-162 yueF S AI-2E family transporter
COOEGACM_00577 4e-225 brpA K Cell envelope-like function transcriptional attenuator common domain protein
COOEGACM_00578 7.4e-310 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
COOEGACM_00579 0.0 M NlpC/P60 family
COOEGACM_00580 1.5e-263 M ErfK YbiS YcfS YnhG
COOEGACM_00581 0.0 bamA GM domain, Protein
COOEGACM_00582 0.0 bamA GM domain, Protein
COOEGACM_00583 3.5e-64 gntR1 K Transcriptional regulator, GntR family
COOEGACM_00584 1.6e-157 V ABC transporter, ATP-binding protein
COOEGACM_00585 5.1e-114
COOEGACM_00586 8e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
COOEGACM_00587 1.7e-100 S Pfam:DUF3816
COOEGACM_00588 0.0 clpE O Belongs to the ClpA ClpB family
COOEGACM_00589 2.9e-27
COOEGACM_00590 2.7e-39 ptsH G phosphocarrier protein HPR
COOEGACM_00591 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
COOEGACM_00592 6.1e-227 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
COOEGACM_00593 2.2e-198 cpoA GT4 M Glycosyltransferase, group 1 family protein
COOEGACM_00594 1.3e-179 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
COOEGACM_00595 9.7e-39 ykuJ S Protein of unknown function (DUF1797)
COOEGACM_00607 4.3e-150 L Belongs to the 'phage' integrase family
COOEGACM_00608 1.4e-20 M Host cell surface-exposed lipoprotein
COOEGACM_00610 1.9e-19 E Zn peptidase
COOEGACM_00611 3.9e-14 3.4.21.88 K Peptidase S24-like
COOEGACM_00613 2.5e-50
COOEGACM_00616 1.5e-23
COOEGACM_00619 7e-78 S Siphovirus Gp157
COOEGACM_00620 4.9e-241 res L Helicase C-terminal domain protein
COOEGACM_00621 6.5e-134 L AAA domain
COOEGACM_00622 4.4e-86
COOEGACM_00623 1.2e-130 S Bifunctional DNA primase/polymerase, N-terminal
COOEGACM_00624 3.5e-222 S Virulence-associated protein E
COOEGACM_00625 2.3e-09 K sequence-specific DNA binding
COOEGACM_00626 3.3e-56 S VRR_NUC
COOEGACM_00633 4.3e-64 arpU S Phage transcriptional regulator, ArpU family
COOEGACM_00634 3.1e-189 L PFAM Integrase catalytic region
COOEGACM_00635 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
COOEGACM_00636 2e-111 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
COOEGACM_00637 2.3e-159 sufD O Uncharacterized protein family (UPF0051)
COOEGACM_00638 2.3e-41 lytE M LysM domain protein
COOEGACM_00639 0.0 oppD EP Psort location Cytoplasmic, score
COOEGACM_00640 1.9e-95 lytE M LysM domain protein
COOEGACM_00641 5.8e-258 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COOEGACM_00642 4.2e-149 xth 3.1.11.2 L exodeoxyribonuclease III
COOEGACM_00643 4.7e-235 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
COOEGACM_00644 5.3e-237 preA 1.3.1.1 C 4Fe-4S dicluster domain
COOEGACM_00645 2.4e-153 yeaE S Aldo keto
COOEGACM_00646 1e-75 hsp O Belongs to the small heat shock protein (HSP20) family
COOEGACM_00647 2.9e-279 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
COOEGACM_00648 2.2e-78 S Psort location Cytoplasmic, score
COOEGACM_00649 6.1e-83 S Short repeat of unknown function (DUF308)
COOEGACM_00650 1e-23
COOEGACM_00651 4.4e-103 V VanZ like family
COOEGACM_00652 2.4e-232 cycA E Amino acid permease
COOEGACM_00653 4.8e-84 perR P Belongs to the Fur family
COOEGACM_00654 2.1e-258 EGP Major facilitator Superfamily
COOEGACM_00655 1.4e-95 tag 3.2.2.20 L glycosylase
COOEGACM_00656 1.9e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
COOEGACM_00657 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
COOEGACM_00658 1.3e-41
COOEGACM_00659 3.8e-256 ytgP S Polysaccharide biosynthesis protein
COOEGACM_00660 1e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
COOEGACM_00661 2.4e-275 pepV 3.5.1.18 E dipeptidase PepV
COOEGACM_00662 1.2e-85 uspA T Belongs to the universal stress protein A family
COOEGACM_00663 9.8e-178 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
COOEGACM_00664 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
COOEGACM_00665 2.2e-113
COOEGACM_00666 2.8e-185 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
COOEGACM_00667 2e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
COOEGACM_00668 1.8e-31
COOEGACM_00669 2e-115 S CAAX protease self-immunity
COOEGACM_00670 1.9e-43
COOEGACM_00672 4.3e-230 L transposase, IS605 OrfB family
COOEGACM_00673 3.1e-66 L PFAM transposase IS200-family protein
COOEGACM_00674 1e-54 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
COOEGACM_00675 2.4e-92 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
COOEGACM_00676 6.2e-105 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
COOEGACM_00677 3.2e-223 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
COOEGACM_00678 1.4e-104 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
COOEGACM_00679 1.8e-212 folP 2.5.1.15 H dihydropteroate synthase
COOEGACM_00680 1.5e-42
COOEGACM_00681 1.5e-32
COOEGACM_00683 3.2e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
COOEGACM_00684 2.4e-150 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
COOEGACM_00685 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
COOEGACM_00686 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
COOEGACM_00687 9.4e-38 yheA S Belongs to the UPF0342 family
COOEGACM_00688 2.4e-220 yhaO L Ser Thr phosphatase family protein
COOEGACM_00689 0.0 L AAA domain
COOEGACM_00690 1.9e-127 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
COOEGACM_00692 4.1e-77 hit FG histidine triad
COOEGACM_00693 4.3e-135 ecsA V ABC transporter, ATP-binding protein
COOEGACM_00694 1e-218 ecsB U ABC transporter
COOEGACM_00695 1.8e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
COOEGACM_00696 0.0 2.7.7.7, 3.4.21.110 D Leucine-rich repeat (LRR) protein
COOEGACM_00697 1.4e-252 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
COOEGACM_00698 3.1e-181 iolS C Aldo keto reductase
COOEGACM_00699 1.1e-167 glsA 3.5.1.2 E Belongs to the glutaminase family
COOEGACM_00700 7.5e-58 ytzB S Small secreted protein
COOEGACM_00701 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
COOEGACM_00702 2.5e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
COOEGACM_00703 7e-48 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
COOEGACM_00704 1.6e-19 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
COOEGACM_00705 3.4e-252 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
COOEGACM_00706 9.3e-119 ybhL S Belongs to the BI1 family
COOEGACM_00707 7.5e-118 yoaK S Protein of unknown function (DUF1275)
COOEGACM_00708 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
COOEGACM_00709 7.4e-160 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
COOEGACM_00710 2.1e-100 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
COOEGACM_00711 4.3e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
COOEGACM_00712 3e-206 dnaB L replication initiation and membrane attachment
COOEGACM_00713 6.2e-171 dnaI L Primosomal protein DnaI
COOEGACM_00714 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
COOEGACM_00715 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
COOEGACM_00716 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
COOEGACM_00717 1.4e-95 yqeG S HAD phosphatase, family IIIA
COOEGACM_00718 1.1e-217 yqeH S Ribosome biogenesis GTPase YqeH
COOEGACM_00719 1.9e-47 yhbY J RNA-binding protein
COOEGACM_00720 1.8e-121 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
COOEGACM_00721 8.1e-111 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
COOEGACM_00722 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
COOEGACM_00723 2.5e-135 yqeM Q Methyltransferase
COOEGACM_00724 3.4e-208 ylbM S Belongs to the UPF0348 family
COOEGACM_00725 2.9e-99 yceD S Uncharacterized ACR, COG1399
COOEGACM_00726 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
COOEGACM_00727 1.5e-121 K response regulator
COOEGACM_00728 1.8e-278 arlS 2.7.13.3 T Histidine kinase
COOEGACM_00729 3.6e-183 yjeM E Amino Acid
COOEGACM_00730 2.2e-75 yjeM E Amino Acid
COOEGACM_00731 4.7e-233 V MatE
COOEGACM_00732 2.5e-68 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
COOEGACM_00733 1e-168 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
COOEGACM_00734 3.6e-42 acyP 3.6.1.7 C Belongs to the acylphosphatase family
COOEGACM_00735 1.1e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COOEGACM_00736 2e-91 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
COOEGACM_00737 6.7e-59 yodB K Transcriptional regulator, HxlR family
COOEGACM_00738 2.3e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
COOEGACM_00739 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
COOEGACM_00740 4.3e-115 rlpA M PFAM NLP P60 protein
COOEGACM_00741 4.7e-117 udk 2.7.1.48 F Cytidine monophosphokinase
COOEGACM_00742 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
COOEGACM_00743 3.5e-67 yneR S Belongs to the HesB IscA family
COOEGACM_00744 0.0 S membrane
COOEGACM_00745 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
COOEGACM_00746 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
COOEGACM_00747 8.9e-101 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
COOEGACM_00748 9e-108 gluP 3.4.21.105 S Peptidase, S54 family
COOEGACM_00749 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
COOEGACM_00750 5.6e-183 glk 2.7.1.2 G Glucokinase
COOEGACM_00751 3.4e-67 yqhL P Rhodanese-like protein
COOEGACM_00752 5.9e-22 S Protein of unknown function (DUF3042)
COOEGACM_00753 2.6e-177 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
COOEGACM_00754 6.8e-264 glnA 6.3.1.2 E glutamine synthetase
COOEGACM_00755 1.2e-296 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
COOEGACM_00756 9.1e-220 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
COOEGACM_00757 3.9e-12
COOEGACM_00758 5.7e-155 P Belongs to the nlpA lipoprotein family
COOEGACM_00759 1.6e-99 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
COOEGACM_00760 1.4e-50 S Iron-sulfur cluster assembly protein
COOEGACM_00761 6.8e-151
COOEGACM_00762 1.4e-179
COOEGACM_00763 4.2e-89 dut S Protein conserved in bacteria
COOEGACM_00764 1.6e-260 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COOEGACM_00767 2.6e-112 K Transcriptional regulator
COOEGACM_00768 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
COOEGACM_00769 1.8e-53 ysxB J Cysteine protease Prp
COOEGACM_00770 1e-44 rpmA J Belongs to the bacterial ribosomal protein bL27 family
COOEGACM_00771 4.3e-132 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
COOEGACM_00772 7.3e-200 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
COOEGACM_00773 3.5e-115 J 2'-5' RNA ligase superfamily
COOEGACM_00774 2.2e-70 yqhY S Asp23 family, cell envelope-related function
COOEGACM_00775 1.2e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
COOEGACM_00776 2.5e-150 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
COOEGACM_00777 5e-214 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
COOEGACM_00778 1.6e-42 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
COOEGACM_00779 3.4e-155 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
COOEGACM_00780 5.3e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
COOEGACM_00781 1.1e-77 argR K Regulates arginine biosynthesis genes
COOEGACM_00782 1e-261 recN L May be involved in recombinational repair of damaged DNA
COOEGACM_00783 4.2e-53
COOEGACM_00784 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
COOEGACM_00785 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
COOEGACM_00786 6.4e-213 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
COOEGACM_00787 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
COOEGACM_00788 1.5e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
COOEGACM_00789 6.3e-249 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
COOEGACM_00790 5.9e-132 stp 3.1.3.16 T phosphatase
COOEGACM_00791 0.0 KLT serine threonine protein kinase
COOEGACM_00792 4.5e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
COOEGACM_00793 1.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
COOEGACM_00794 7e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
COOEGACM_00795 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
COOEGACM_00796 3e-57 asp S Asp23 family, cell envelope-related function
COOEGACM_00797 0.0 yloV S DAK2 domain fusion protein YloV
COOEGACM_00798 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
COOEGACM_00799 1.8e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
COOEGACM_00800 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
COOEGACM_00801 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
COOEGACM_00802 0.0 smc D Required for chromosome condensation and partitioning
COOEGACM_00803 9.4e-185 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
COOEGACM_00804 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
COOEGACM_00805 1e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
COOEGACM_00806 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
COOEGACM_00807 7.7e-37 ylqC S Belongs to the UPF0109 family
COOEGACM_00808 6.9e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
COOEGACM_00809 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
COOEGACM_00810 2.9e-260 yfnA E amino acid
COOEGACM_00811 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
COOEGACM_00812 2.2e-170 L Belongs to the 'phage' integrase family
COOEGACM_00813 1.8e-45
COOEGACM_00814 2.2e-15 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
COOEGACM_00815 1.4e-38
COOEGACM_00818 2.5e-19
COOEGACM_00819 4.9e-10
COOEGACM_00820 2.2e-34
COOEGACM_00821 1.6e-52 S Mazg nucleotide pyrophosphohydrolase
COOEGACM_00822 3.3e-160 xth 3.1.11.2 L exodeoxyribonuclease III
COOEGACM_00823 1.1e-261 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COOEGACM_00824 1.1e-83
COOEGACM_00825 9.7e-186 lacR K Transcriptional regulator
COOEGACM_00826 0.0 lacS G Transporter
COOEGACM_00827 0.0 lacZ 3.2.1.23 G -beta-galactosidase
COOEGACM_00828 2.4e-147 D nuclear chromosome segregation
COOEGACM_00829 5.6e-24 D nuclear chromosome segregation
COOEGACM_00830 2.9e-179 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
COOEGACM_00831 1.7e-157 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
COOEGACM_00832 2.6e-129 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
COOEGACM_00833 1.4e-223 mdtG EGP Major facilitator Superfamily
COOEGACM_00834 1.3e-167 T Calcineurin-like phosphoesterase superfamily domain
COOEGACM_00835 9.2e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
COOEGACM_00837 1.7e-119 sdaAB 4.3.1.17 E Serine dehydratase beta chain
COOEGACM_00838 2.6e-142 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
COOEGACM_00839 1.2e-105 ahpC 1.11.1.15 O Peroxiredoxin
COOEGACM_00840 0.0 trxB2 1.8.1.9 C Thioredoxin domain
COOEGACM_00841 6.8e-88 M LPXTG-motif cell wall anchor domain protein
COOEGACM_00842 0.0 M LPXTG-motif cell wall anchor domain protein
COOEGACM_00843 1e-157 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
COOEGACM_00844 2.9e-190 nss M transferase activity, transferring glycosyl groups
COOEGACM_00845 4.3e-209 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
COOEGACM_00846 2.8e-298 M transferase activity, transferring glycosyl groups
COOEGACM_00847 3.2e-294 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
COOEGACM_00848 5.7e-166 asp3 S Accessory Sec secretory system ASP3
COOEGACM_00849 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
COOEGACM_00850 4.4e-291 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
COOEGACM_00851 3.2e-253 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
COOEGACM_00853 0.0 M family 8
COOEGACM_00854 1.1e-34 GT2,GT4 M Glycosyltransferase GT-D fold
COOEGACM_00855 1.1e-261 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COOEGACM_00856 3.1e-15 sraP UW this gene contains a nucleotide ambiguity which may be the result of a sequencing error
COOEGACM_00858 3.1e-189 L PFAM Integrase catalytic region
COOEGACM_00859 8.7e-22 UW Tetratricopeptide repeat
COOEGACM_00864 4.3e-269 pipD E Dipeptidase
COOEGACM_00865 2.5e-311 yjbQ P TrkA C-terminal domain protein
COOEGACM_00866 1e-24 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
COOEGACM_00867 5.4e-294 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
COOEGACM_00868 1.9e-89
COOEGACM_00869 2.8e-35
COOEGACM_00870 9.3e-62 K DNA-templated transcription, initiation
COOEGACM_00871 4.7e-20 K DNA-templated transcription, initiation
COOEGACM_00872 4.7e-126
COOEGACM_00873 9.7e-65 K Transcriptional regulator, HxlR family
COOEGACM_00874 3.7e-161 brpA K Cell envelope-like function transcriptional attenuator common domain protein
COOEGACM_00875 3.7e-133 epsB M biosynthesis protein
COOEGACM_00876 1.3e-118 ywqD 2.7.10.1 D Capsular exopolysaccharide family
COOEGACM_00877 3.6e-139 cps2D 5.1.3.2 M RmlD substrate binding domain
COOEGACM_00878 4.2e-89 tuaA M Bacterial sugar transferase
COOEGACM_00879 6.5e-41 tuaG GT2 M Glycosyltransferase like family 2
COOEGACM_00880 1.8e-32 M Glycosyltransferase
COOEGACM_00881 1.3e-22 S EpsG family
COOEGACM_00882 1.3e-70 M Glycosyltransferase sugar-binding region containing DXD motif
COOEGACM_00883 1.2e-136 S Membrane protein involved in the export of O-antigen and teichoic acid
COOEGACM_00884 6.2e-159 L PFAM Integrase catalytic region
COOEGACM_00887 9.2e-281 L Transposase IS66 family
COOEGACM_00888 3.1e-62 XK27_01125 L PFAM IS66 Orf2 family protein
COOEGACM_00890 1.1e-13 gspA M lipopolysaccharide 3-alpha-galactosyltransferase activity
COOEGACM_00891 1.1e-250 L PFAM transposase, IS4 family protein
COOEGACM_00892 9e-147 S Protein of unknown function (DUF3800)
COOEGACM_00894 0.0 snf 2.7.11.1 KL domain protein
COOEGACM_00895 2.9e-142 ywqE 3.1.3.48 GM PHP domain protein
COOEGACM_00896 4.7e-176 M Glycosyl hydrolases family 25
COOEGACM_00897 4.9e-207 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
COOEGACM_00898 0.0 sbcC L Putative exonuclease SbcCD, C subunit
COOEGACM_00899 1.7e-93 L nuclease
COOEGACM_00900 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
COOEGACM_00901 6.9e-69
COOEGACM_00902 1.7e-102 fic D Fic/DOC family
COOEGACM_00903 4.4e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
COOEGACM_00904 4.4e-152 3.1.3.73 G Belongs to the phosphoglycerate mutase family
COOEGACM_00905 3.7e-30
COOEGACM_00906 3.1e-54
COOEGACM_00907 5.4e-25
COOEGACM_00909 7.9e-109 lssY 3.6.1.27 I Acid phosphatase homologues
COOEGACM_00910 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
COOEGACM_00911 1.6e-227 clcA_2 P Chloride transporter, ClC family
COOEGACM_00912 3.6e-117 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
COOEGACM_00913 1.6e-146 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
COOEGACM_00914 5.1e-137 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
COOEGACM_00915 1.8e-50
COOEGACM_00916 0.0 S SEC-C Motif Domain Protein
COOEGACM_00918 3.1e-62 XK27_01125 L PFAM IS66 Orf2 family protein
COOEGACM_00919 9.2e-281 L Transposase IS66 family
COOEGACM_00920 7.1e-121 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
COOEGACM_00921 6.9e-72
COOEGACM_00922 2.8e-174
COOEGACM_00923 8e-172 fecB P Periplasmic binding protein
COOEGACM_00924 2.9e-134 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
COOEGACM_00925 4.8e-55 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COOEGACM_00926 1.6e-18
COOEGACM_00927 2.2e-94 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
COOEGACM_00928 7.5e-75 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
COOEGACM_00929 2e-222 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
COOEGACM_00930 9.8e-83 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
COOEGACM_00931 4.5e-183 moeB 2.7.7.73, 2.7.7.80 H ThiF family
COOEGACM_00932 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
COOEGACM_00933 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
COOEGACM_00934 1.1e-98 narJ C nitrate reductase molybdenum cofactor assembly chaperone
COOEGACM_00935 2.5e-129 narI 1.7.5.1 C Nitrate reductase
COOEGACM_00936 1.2e-150 EG EamA-like transporter family
COOEGACM_00937 2.5e-118 L Integrase
COOEGACM_00938 1.9e-158 rssA S Phospholipase, patatin family
COOEGACM_00939 3e-201 xerS L Belongs to the 'phage' integrase family
COOEGACM_00941 4.7e-57 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
COOEGACM_00942 1.5e-258 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
COOEGACM_00943 1.5e-134 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
COOEGACM_00944 2.4e-136 accA 2.1.3.15, 6.4.1.2 I alpha subunit
COOEGACM_00945 5.3e-128 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
COOEGACM_00954 8.1e-55
COOEGACM_00955 3.1e-113 frnE Q DSBA-like thioredoxin domain
COOEGACM_00956 3.1e-189 L PFAM Integrase catalytic region
COOEGACM_00957 1.2e-165 I alpha/beta hydrolase fold
COOEGACM_00960 2.6e-23 S Phage derived protein Gp49-like (DUF891)
COOEGACM_00961 1.8e-44 L Belongs to the 'phage' integrase family
COOEGACM_00962 1.1e-250 L PFAM transposase, IS4 family protein
COOEGACM_00963 1.9e-150 lysA2 M Glycosyl hydrolases family 25
COOEGACM_00964 3.7e-33 S Bacteriophage holin of superfamily 6 (Holin_LLH)
COOEGACM_00971 2.1e-41 GT2,GT4 LM gp58-like protein
COOEGACM_00972 7.7e-142 ydhO 3.4.14.13 M Prophage endopeptidase tail
COOEGACM_00973 6.3e-85 S Phage tail protein
COOEGACM_00974 1.9e-236 M Phage tail tape measure protein TP901
COOEGACM_00975 2.6e-13 S Phage tail assembly chaperone proteins, TAC
COOEGACM_00976 5.6e-80 S Phage tail tube protein
COOEGACM_00977 6.8e-20 S Protein of unknown function (DUF806)
COOEGACM_00978 1.7e-35 S exonuclease activity
COOEGACM_00979 3.8e-10 S Phage head-tail joining protein
COOEGACM_00980 5.1e-49 S Phage gp6-like head-tail connector protein
COOEGACM_00981 4.7e-171 S Phage capsid family
COOEGACM_00982 3.3e-66 S Clp protease
COOEGACM_00983 3e-194 S Phage portal protein
COOEGACM_00984 4.3e-288 S overlaps another CDS with the same product name
COOEGACM_00985 1.7e-65 L Phage terminase, small subunit
COOEGACM_00986 1.4e-66 L HNH nucleases
COOEGACM_00987 1.3e-171 bcgIA 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
COOEGACM_00988 3.9e-90 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
COOEGACM_00989 1.6e-08
COOEGACM_00992 2.4e-74
COOEGACM_00997 2.9e-70 Q DNA (cytosine-5-)-methyltransferase activity
COOEGACM_01002 5.9e-124
COOEGACM_01004 5.9e-68
COOEGACM_01006 1.5e-116 L DnaD domain protein
COOEGACM_01009 7.4e-20
COOEGACM_01015 2.8e-10 K Helix-turn-helix XRE-family like proteins
COOEGACM_01016 3e-79 3.4.21.88 K Peptidase S24-like
COOEGACM_01018 2.4e-18
COOEGACM_01019 5.1e-78
COOEGACM_01020 3.3e-85 L PFAM transposase IS200-family protein
COOEGACM_01021 3e-262 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COOEGACM_01022 7.1e-142 L Belongs to the 'phage' integrase family
COOEGACM_01024 2.4e-46 yrvD S Pfam:DUF1049
COOEGACM_01025 6.9e-150 3.1.3.102, 3.1.3.104 S hydrolase
COOEGACM_01026 3.1e-89 ntd 2.4.2.6 F Nucleoside
COOEGACM_01027 2e-18
COOEGACM_01028 4.2e-166 S Alpha/beta hydrolase of unknown function (DUF915)
COOEGACM_01029 6.2e-114 yviA S Protein of unknown function (DUF421)
COOEGACM_01030 1.9e-69 S Protein of unknown function (DUF3290)
COOEGACM_01031 6e-42 ybaN S Protein of unknown function (DUF454)
COOEGACM_01032 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COOEGACM_01033 4.6e-157 endA V DNA/RNA non-specific endonuclease
COOEGACM_01034 3.9e-254 yifK E Amino acid permease
COOEGACM_01036 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
COOEGACM_01037 6.4e-232 N Uncharacterized conserved protein (DUF2075)
COOEGACM_01038 3.9e-122 S SNARE associated Golgi protein
COOEGACM_01039 0.0 uvrA3 L excinuclease ABC, A subunit
COOEGACM_01040 8.5e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COOEGACM_01041 5.4e-57 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COOEGACM_01042 8.3e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
COOEGACM_01043 2.5e-144 S DUF218 domain
COOEGACM_01044 0.0 ubiB S ABC1 family
COOEGACM_01045 1.1e-245 yhdP S Transporter associated domain
COOEGACM_01046 2.1e-73 copY K Copper transport repressor CopY TcrY
COOEGACM_01047 2.4e-243 EGP Major facilitator Superfamily
COOEGACM_01049 3.1e-62 XK27_01125 L PFAM IS66 Orf2 family protein
COOEGACM_01050 9.2e-281 L Transposase IS66 family
COOEGACM_01051 5.8e-74 yeaL S UPF0756 membrane protein
COOEGACM_01052 1e-77 yphH S Cupin domain
COOEGACM_01053 4.8e-96 K Acetyltransferase (GNAT) domain
COOEGACM_01054 1.3e-159 S Alpha beta hydrolase
COOEGACM_01055 6e-157 gspA M family 8
COOEGACM_01056 8.6e-119 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
COOEGACM_01057 1.8e-92
COOEGACM_01058 1.2e-160 degV S EDD domain protein, DegV family
COOEGACM_01059 0.0 FbpA K Fibronectin-binding protein
COOEGACM_01060 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
COOEGACM_01061 4.5e-205 carA 6.3.5.5 F Belongs to the CarA family
COOEGACM_01062 5.3e-175 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
COOEGACM_01063 6.3e-73 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
COOEGACM_01064 1.5e-65 esbA S Family of unknown function (DUF5322)
COOEGACM_01065 1.8e-71 rnhA 3.1.26.4 L Ribonuclease HI
COOEGACM_01066 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
COOEGACM_01067 7.7e-85 F Belongs to the NrdI family
COOEGACM_01068 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
COOEGACM_01069 7.8e-100 ypsA S Belongs to the UPF0398 family
COOEGACM_01070 4.4e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
COOEGACM_01071 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
COOEGACM_01072 1.8e-162 EG EamA-like transporter family
COOEGACM_01073 3e-125 dnaD L DnaD domain protein
COOEGACM_01074 1.5e-86 ypmB S Protein conserved in bacteria
COOEGACM_01075 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
COOEGACM_01076 1.3e-171 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
COOEGACM_01077 1.6e-161 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
COOEGACM_01078 4.2e-214 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
COOEGACM_01079 1.7e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
COOEGACM_01080 7.1e-89 S Protein of unknown function (DUF1440)
COOEGACM_01081 6.2e-294 L Transposase
COOEGACM_01082 0.0 rafA 3.2.1.22 G alpha-galactosidase
COOEGACM_01083 1.5e-186 galR K Periplasmic binding protein-like domain
COOEGACM_01084 3.2e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
COOEGACM_01085 1.1e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
COOEGACM_01086 1.3e-123 lrgB M LrgB-like family
COOEGACM_01087 1.9e-66 lrgA S LrgA family
COOEGACM_01088 3.2e-130 lytT K response regulator receiver
COOEGACM_01089 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
COOEGACM_01090 6.8e-148 f42a O Band 7 protein
COOEGACM_01091 2.6e-263 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
COOEGACM_01092 7.1e-155 yitU 3.1.3.104 S hydrolase
COOEGACM_01093 6e-38 S Cytochrome B5
COOEGACM_01094 7e-113 nreC K PFAM regulatory protein LuxR
COOEGACM_01095 1.6e-160 hipB K Helix-turn-helix
COOEGACM_01096 2.8e-57 yitW S Iron-sulfur cluster assembly protein
COOEGACM_01097 1e-270 sufB O assembly protein SufB
COOEGACM_01098 6.5e-81 nifU C SUF system FeS assembly protein, NifU family
COOEGACM_01099 4e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
COOEGACM_01100 4.6e-241 sufD O FeS assembly protein SufD
COOEGACM_01101 1.9e-144 sufC O FeS assembly ATPase SufC
COOEGACM_01102 1.2e-31 feoA P FeoA domain
COOEGACM_01103 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
COOEGACM_01104 8.3e-268 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
COOEGACM_01105 1.7e-156 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
COOEGACM_01106 1.6e-64 ydiI Q Thioesterase superfamily
COOEGACM_01107 3e-107 yvrI K sigma factor activity
COOEGACM_01108 6.2e-200 G Transporter, major facilitator family protein
COOEGACM_01109 0.0 S Bacterial membrane protein YfhO
COOEGACM_01110 1.6e-102 T Ion transport 2 domain protein
COOEGACM_01111 1.4e-75 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
COOEGACM_01112 2.5e-225 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
COOEGACM_01113 1e-94 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
COOEGACM_01114 1.8e-179 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
COOEGACM_01115 9e-178 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
COOEGACM_01117 0.0 L PLD-like domain
COOEGACM_01118 4.3e-36 higA K addiction module antidote protein HigA
COOEGACM_01119 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
COOEGACM_01120 4.6e-43 2.1.1.72, 3.1.21.3 L Type I restriction modification DNA specificity domain
COOEGACM_01121 4.5e-180 xerC L Belongs to the 'phage' integrase family
COOEGACM_01122 7.9e-21 hsdS 3.1.21.3 L Type I restriction modification DNA specificity domain
COOEGACM_01123 1.5e-89 hsdS 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
COOEGACM_01124 1.2e-299 2.1.1.72 V type I restriction-modification system
COOEGACM_01125 2.8e-58 yhaI S Protein of unknown function (DUF805)
COOEGACM_01126 5e-44
COOEGACM_01127 5.8e-23 M LPXTG-motif cell wall anchor domain protein
COOEGACM_01128 7e-12
COOEGACM_01129 4.1e-128 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COOEGACM_01130 2.6e-49 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COOEGACM_01131 1.5e-26 yeeE S Sulphur transport
COOEGACM_01132 1.7e-95 L PFAM Integrase catalytic region
COOEGACM_01133 1.6e-200 L Transposase IS66 family
COOEGACM_01134 4.3e-27 L Transposase IS66 family
COOEGACM_01135 2.9e-18 XK27_01125 L PFAM IS66 Orf2 family protein
COOEGACM_01136 9.5e-28 XK27_01125 L PFAM IS66 Orf2 family protein
COOEGACM_01138 3.4e-43
COOEGACM_01139 9.9e-147 2.4.1.52 GT4 M Glycosyl transferases group 1
COOEGACM_01140 3.9e-218 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
COOEGACM_01141 9.7e-24
COOEGACM_01142 2.2e-159 iolT EGP Major facilitator Superfamily
COOEGACM_01143 5.8e-41
COOEGACM_01145 2.1e-89 K Acetyltransferase (GNAT) domain
COOEGACM_01146 5.9e-288 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
COOEGACM_01147 3.8e-230 gntT EG Gluconate
COOEGACM_01148 2e-92 K Transcriptional regulator, LacI family
COOEGACM_01149 3.1e-189 L PFAM Integrase catalytic region
COOEGACM_01150 1e-38 K Transcriptional regulator, LacI family
COOEGACM_01151 4.5e-288 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
COOEGACM_01152 4.2e-95
COOEGACM_01153 2.3e-24
COOEGACM_01154 8.7e-63 asp S Asp23 family, cell envelope-related function
COOEGACM_01155 5.9e-88 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
COOEGACM_01157 1.6e-49
COOEGACM_01158 4.1e-68 yqkB S Belongs to the HesB IscA family
COOEGACM_01159 1.1e-172 ppaC 3.6.1.1 C inorganic pyrophosphatase
COOEGACM_01160 3.5e-82 F NUDIX domain
COOEGACM_01161 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
COOEGACM_01162 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
COOEGACM_01163 7.9e-106 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
COOEGACM_01164 4.9e-170 lacX 5.1.3.3 G Aldose 1-epimerase
COOEGACM_01165 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
COOEGACM_01166 9e-164 dprA LU DNA protecting protein DprA
COOEGACM_01167 5e-142 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
COOEGACM_01168 1.1e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
COOEGACM_01169 4.4e-35 yozE S Belongs to the UPF0346 family
COOEGACM_01170 3.7e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
COOEGACM_01171 3.4e-169 ypmR E lipolytic protein G-D-S-L family
COOEGACM_01172 4.4e-152 DegV S EDD domain protein, DegV family
COOEGACM_01173 5.3e-113 hlyIII S protein, hemolysin III
COOEGACM_01174 5.1e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
COOEGACM_01175 2.2e-192 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
COOEGACM_01176 0.0 yfmR S ABC transporter, ATP-binding protein
COOEGACM_01177 3e-226 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
COOEGACM_01178 1.3e-235 S Tetratricopeptide repeat protein
COOEGACM_01179 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
COOEGACM_01180 1.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
COOEGACM_01181 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
COOEGACM_01182 7.6e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
COOEGACM_01183 2.5e-13 M Lysin motif
COOEGACM_01184 1.5e-269 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
COOEGACM_01185 1.3e-193 ypbB 5.1.3.1 S Helix-turn-helix domain
COOEGACM_01186 7.6e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
COOEGACM_01187 5e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
COOEGACM_01188 9.4e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
COOEGACM_01189 2.9e-137 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
COOEGACM_01190 1.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
COOEGACM_01191 1.7e-165 xerD D recombinase XerD
COOEGACM_01192 4.6e-168 cvfB S S1 domain
COOEGACM_01193 1.4e-270 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
COOEGACM_01194 0.0 dnaE 2.7.7.7 L DNA polymerase
COOEGACM_01195 5.2e-30 S Protein of unknown function (DUF2929)
COOEGACM_01196 3.9e-237 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
COOEGACM_01197 2.3e-153 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
COOEGACM_01198 1.7e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
COOEGACM_01199 9.1e-220 patA 2.6.1.1 E Aminotransferase
COOEGACM_01200 1.7e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
COOEGACM_01201 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
COOEGACM_01202 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
COOEGACM_01203 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
COOEGACM_01204 5.8e-146 recO L Involved in DNA repair and RecF pathway recombination
COOEGACM_01205 2.8e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
COOEGACM_01206 3.8e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
COOEGACM_01207 6e-69 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
COOEGACM_01208 5.3e-184 phoH T phosphate starvation-inducible protein PhoH
COOEGACM_01209 4e-173 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
COOEGACM_01210 3.3e-90 bioY S BioY family
COOEGACM_01211 5.2e-259 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COOEGACM_01212 1.7e-265 argH 4.3.2.1 E argininosuccinate lyase
COOEGACM_01213 1.1e-236 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
COOEGACM_01214 4.9e-187 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
COOEGACM_01215 6.6e-70 yqeY S YqeY-like protein
COOEGACM_01216 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
COOEGACM_01217 3.8e-263 glnPH2 P ABC transporter permease
COOEGACM_01218 3.4e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
COOEGACM_01219 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
COOEGACM_01220 4e-169 yniA G Phosphotransferase enzyme family
COOEGACM_01221 4.2e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
COOEGACM_01222 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
COOEGACM_01223 1.2e-52
COOEGACM_01224 2.1e-129 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
COOEGACM_01225 7.5e-180 prmA J Ribosomal protein L11 methyltransferase
COOEGACM_01226 7.5e-58
COOEGACM_01227 1.5e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
COOEGACM_01229 1.1e-200 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
COOEGACM_01230 1.7e-273 pipD E Dipeptidase
COOEGACM_01231 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
COOEGACM_01232 1.2e-71 S Metallo-beta-lactamase superfamily
COOEGACM_01233 7.3e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
COOEGACM_01234 0.0 dnaK O Heat shock 70 kDa protein
COOEGACM_01235 4.3e-74 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
COOEGACM_01236 1.8e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
COOEGACM_01237 2e-64
COOEGACM_01238 1.5e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
COOEGACM_01239 1.8e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
COOEGACM_01240 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
COOEGACM_01241 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
COOEGACM_01242 1.7e-48 ylxQ J ribosomal protein
COOEGACM_01243 1e-44 ylxR K Protein of unknown function (DUF448)
COOEGACM_01244 2.8e-216 nusA K Participates in both transcription termination and antitermination
COOEGACM_01245 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
COOEGACM_01246 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
COOEGACM_01247 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
COOEGACM_01248 3.7e-235 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
COOEGACM_01249 8.4e-137 cdsA 2.7.7.41 I Belongs to the CDS family
COOEGACM_01250 7.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
COOEGACM_01251 4.8e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
COOEGACM_01252 5.9e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
COOEGACM_01253 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
COOEGACM_01254 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
COOEGACM_01255 2e-183 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COOEGACM_01256 5.4e-49 yazA L GIY-YIG catalytic domain protein
COOEGACM_01257 4.1e-141 yabB 2.1.1.223 L Methyltransferase small domain
COOEGACM_01258 7.8e-117 plsC 2.3.1.51 I Acyltransferase
COOEGACM_01259 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
COOEGACM_01260 3.9e-35 ynzC S UPF0291 protein
COOEGACM_01261 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
COOEGACM_01262 5.2e-212 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
COOEGACM_01263 2.3e-127 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
COOEGACM_01265 3.5e-79 S Fic/DOC family
COOEGACM_01267 2.4e-24
COOEGACM_01272 1e-37 M CHAP domain
COOEGACM_01274 6.8e-180 U type IV secretory pathway VirB4
COOEGACM_01275 8.1e-24
COOEGACM_01277 2.3e-64
COOEGACM_01278 1.5e-191 U TraM recognition site of TraD and TraG
COOEGACM_01283 3e-148 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
COOEGACM_01285 1.9e-135 topA2 5.99.1.2 G Topoisomerase IA
COOEGACM_01286 4.1e-52 L Protein of unknown function (DUF3991)
COOEGACM_01289 5.6e-33 XK27_00515 D Glucan-binding protein C
COOEGACM_01291 9.9e-29 S YoeB-like toxin of bacterial type II toxin-antitoxin system
COOEGACM_01292 4.8e-21 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
COOEGACM_01293 5e-09 sspD D PFAM Glucan-binding protein C
COOEGACM_01295 3.4e-97 L Belongs to the 'phage' integrase family
COOEGACM_01296 2.5e-21 D nuclear chromosome segregation
COOEGACM_01300 4e-36 lytE M Lysin motif
COOEGACM_01302 7e-62
COOEGACM_01304 5.2e-58 ruvB 3.6.4.12 L four-way junction helicase activity
COOEGACM_01305 1.7e-23 S YoeB-like toxin of bacterial type II toxin-antitoxin system
COOEGACM_01306 3.7e-25 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
COOEGACM_01311 2.3e-15 S Domain of Unknown Function with PDB structure (DUF3850)
COOEGACM_01312 1.3e-54 srtA 3.4.22.70 M sortase family
COOEGACM_01322 2.4e-170 L PFAM transposase IS116 IS110 IS902 family
COOEGACM_01337 2.4e-19 L Psort location Cytoplasmic, score
COOEGACM_01339 4e-11 S Domain of unknown function (DUF771)
COOEGACM_01341 4.5e-15 S sequence-specific DNA binding
COOEGACM_01342 1.5e-08 E Zn peptidase
COOEGACM_01343 3.1e-92 L Belongs to the 'phage' integrase family
COOEGACM_01345 2.5e-88
COOEGACM_01346 9.2e-92 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
COOEGACM_01347 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
COOEGACM_01348 2.1e-154 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
COOEGACM_01349 2.4e-175 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
COOEGACM_01350 2.3e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
COOEGACM_01351 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
COOEGACM_01352 7.6e-09
COOEGACM_01353 7.8e-263 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COOEGACM_01354 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
COOEGACM_01355 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
COOEGACM_01356 5.3e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
COOEGACM_01357 1.8e-237 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
COOEGACM_01358 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
COOEGACM_01359 3.5e-163 S Tetratricopeptide repeat
COOEGACM_01360 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
COOEGACM_01361 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
COOEGACM_01362 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
COOEGACM_01363 6.1e-294 L Transposase
COOEGACM_01364 5.3e-147 holA 2.7.7.7 L DNA polymerase III delta subunit
COOEGACM_01365 0.0 comEC S Competence protein ComEC
COOEGACM_01366 3.1e-89 comEB 3.5.4.12 F ComE operon protein 2
COOEGACM_01367 1.4e-78 comEA L Competence protein ComEA
COOEGACM_01368 4.6e-199 ylbL T Belongs to the peptidase S16 family
COOEGACM_01369 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
COOEGACM_01370 1.2e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
COOEGACM_01371 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
COOEGACM_01372 2.9e-221 ftsW D Belongs to the SEDS family
COOEGACM_01373 5.2e-259 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COOEGACM_01374 0.0 typA T GTP-binding protein TypA
COOEGACM_01375 6.3e-137 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
COOEGACM_01376 1.4e-47 yktA S Belongs to the UPF0223 family
COOEGACM_01377 1.2e-274 lpdA 1.8.1.4 C Dehydrogenase
COOEGACM_01378 3.5e-228 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
COOEGACM_01379 8.1e-182 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
COOEGACM_01380 9.8e-208 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
COOEGACM_01381 1.3e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
COOEGACM_01382 8.8e-81
COOEGACM_01383 9.8e-32 ykzG S Belongs to the UPF0356 family
COOEGACM_01384 2.1e-182 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
COOEGACM_01385 5.7e-29
COOEGACM_01386 2.8e-138 mltD CBM50 M NlpC P60 family protein
COOEGACM_01388 6.5e-57
COOEGACM_01389 7.7e-121 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
COOEGACM_01390 1.2e-64 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
COOEGACM_01391 6.7e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
COOEGACM_01392 4.7e-216 patA 2.6.1.1 E Aminotransferase
COOEGACM_01393 4.7e-140 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
COOEGACM_01394 1.5e-172 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
COOEGACM_01395 1.6e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
COOEGACM_01396 1.3e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
COOEGACM_01397 7.9e-249 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
COOEGACM_01398 5.1e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
COOEGACM_01399 9.9e-183 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
COOEGACM_01400 1.1e-250 L PFAM transposase, IS4 family protein
COOEGACM_01401 8.1e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
COOEGACM_01402 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
COOEGACM_01403 9e-119 S Repeat protein
COOEGACM_01404 4.9e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
COOEGACM_01405 1.4e-217 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
COOEGACM_01406 2.2e-57 XK27_04120 S Putative amino acid metabolism
COOEGACM_01407 9.2e-217 iscS 2.8.1.7 E Aminotransferase class V
COOEGACM_01408 8.5e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
COOEGACM_01410 1.8e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
COOEGACM_01411 4.2e-32 cspA K Cold shock protein
COOEGACM_01412 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
COOEGACM_01413 1.6e-36 divIVA D DivIVA domain protein
COOEGACM_01414 1.7e-145 ylmH S S4 domain protein
COOEGACM_01415 3.2e-40 yggT S YGGT family
COOEGACM_01416 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
COOEGACM_01417 1.7e-224 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
COOEGACM_01418 2.9e-254 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
COOEGACM_01419 6.1e-141 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
COOEGACM_01420 1.6e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
COOEGACM_01421 7.7e-263 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
COOEGACM_01422 2.6e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
COOEGACM_01423 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
COOEGACM_01424 1.5e-56 ftsL D Cell division protein FtsL
COOEGACM_01425 1.9e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
COOEGACM_01426 4.5e-76 mraZ K Belongs to the MraZ family
COOEGACM_01427 1.5e-56
COOEGACM_01428 1.2e-10 S Protein of unknown function (DUF4044)
COOEGACM_01429 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
COOEGACM_01430 6.1e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
COOEGACM_01431 3.1e-161 rrmA 2.1.1.187 H Methyltransferase
COOEGACM_01432 1.1e-181 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
COOEGACM_01433 1.4e-14 L Transposase
COOEGACM_01434 9.2e-297 L Transposase IS66 family
COOEGACM_01435 5.4e-67 XK27_01125 L PFAM IS66 Orf2 family protein
COOEGACM_01439 1.9e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
COOEGACM_01440 6e-154 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
COOEGACM_01441 5.2e-116 yjbM 2.7.6.5 S RelA SpoT domain protein
COOEGACM_01442 6.9e-113 yjbH Q Thioredoxin
COOEGACM_01443 1.4e-264 pipD E Dipeptidase
COOEGACM_01444 1.8e-200 coiA 3.6.4.12 S Competence protein
COOEGACM_01445 1.4e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
COOEGACM_01446 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
COOEGACM_01447 1.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
COOEGACM_01448 3.7e-85 L Transposase
COOEGACM_01449 3.1e-97 L Transposase
COOEGACM_01451 5.4e-67 XK27_01125 L PFAM IS66 Orf2 family protein
COOEGACM_01452 9.2e-297 L Transposase IS66 family
COOEGACM_01453 9.2e-281 L Transposase IS66 family
COOEGACM_01454 3.1e-62 XK27_01125 L PFAM IS66 Orf2 family protein
COOEGACM_01477 5.5e-110 dedA S SNARE-like domain protein
COOEGACM_01478 1.9e-102 S Protein of unknown function (DUF1461)
COOEGACM_01479 2.7e-132 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
COOEGACM_01480 6.6e-93 yutD S Protein of unknown function (DUF1027)
COOEGACM_01481 4.7e-111 S Calcineurin-like phosphoesterase
COOEGACM_01482 2.2e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COOEGACM_01483 7.7e-146 ytxK 2.1.1.72 L N-6 DNA Methylase
COOEGACM_01485 1.8e-69
COOEGACM_01486 1.1e-41
COOEGACM_01487 1.1e-77 NU general secretion pathway protein
COOEGACM_01488 1e-38 comGC U competence protein ComGC
COOEGACM_01490 4.1e-143 M Glycosyl hydrolases family 25
COOEGACM_01491 4.6e-31 S Bacteriophage holin of superfamily 6 (Holin_LLH)
COOEGACM_01492 2.6e-36 S Bacteriophage holin family
COOEGACM_01494 1.1e-11
COOEGACM_01496 0.0 GT2,GT4 LM gp58-like protein
COOEGACM_01497 1.3e-57
COOEGACM_01498 0.0 M Phage tail tape measure protein TP901
COOEGACM_01499 4.8e-37
COOEGACM_01500 1.3e-59
COOEGACM_01501 4e-71 S Phage tail tube protein, TTP
COOEGACM_01502 1.7e-52
COOEGACM_01503 3.1e-77
COOEGACM_01504 4.4e-53
COOEGACM_01505 1.6e-35
COOEGACM_01506 5.1e-174 S Phage major capsid protein E
COOEGACM_01507 1.4e-52
COOEGACM_01508 1.1e-65 S Domain of unknown function (DUF4355)
COOEGACM_01509 1.1e-147 S Phage Mu protein F like protein
COOEGACM_01510 6.7e-236 S Phage portal protein, SPP1 Gp6-like
COOEGACM_01511 3.1e-221 S Terminase-like family
COOEGACM_01512 1.4e-108 xtmA L Terminase small subunit
COOEGACM_01513 2e-59 S HicB_like antitoxin of bacterial toxin-antitoxin system
COOEGACM_01514 1.3e-19 S Type I restriction modification DNA specificity domain
COOEGACM_01516 3.6e-145 2.1.1.72 V type I restriction-modification system
COOEGACM_01517 3.4e-82 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
COOEGACM_01518 5.6e-66 yhdJ 2.1.1.72 L DNA methylase
COOEGACM_01521 3.7e-29
COOEGACM_01524 3.4e-39 S Protein of unknown function (DUF1064)
COOEGACM_01526 6.8e-19
COOEGACM_01527 4.8e-15
COOEGACM_01531 3.7e-25
COOEGACM_01534 3.1e-57 dnaC 3.4.21.53 L IstB-like ATP binding protein
COOEGACM_01535 4.1e-55 ybl78 L DnaD domain protein
COOEGACM_01536 4.3e-63 S Putative HNHc nuclease
COOEGACM_01537 1.6e-84 S Protein of unknown function (DUF669)
COOEGACM_01538 5.1e-122 S AAA domain
COOEGACM_01539 4.6e-62 S Bacteriophage Mu Gam like protein
COOEGACM_01540 6.7e-13 S Domain of unknown function (DUF1508)
COOEGACM_01544 7.8e-68 S DNA binding
COOEGACM_01546 1.2e-36 K Helix-turn-helix XRE-family like proteins
COOEGACM_01547 4.5e-42 E Zn peptidase
COOEGACM_01548 3.3e-19
COOEGACM_01549 3.1e-38
COOEGACM_01550 3.3e-90 S Protein of unknown function (DUF3644)
COOEGACM_01553 4e-125 int L COG1961 Site-specific recombinases, DNA invertase Pin homologs
COOEGACM_01554 2.2e-185 comGB NU type II secretion system
COOEGACM_01555 2.3e-184 comGA NU Type II IV secretion system protein
COOEGACM_01556 3.5e-132 yebC K Transcriptional regulatory protein
COOEGACM_01557 4e-124
COOEGACM_01558 7.1e-181 ccpA K catabolite control protein A
COOEGACM_01559 1.6e-210 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
COOEGACM_01560 4.9e-28
COOEGACM_01561 6.5e-38 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
COOEGACM_01562 5.3e-148 ykuT M mechanosensitive ion channel
COOEGACM_01563 1.5e-152 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
COOEGACM_01564 2.2e-73 ykuL S (CBS) domain
COOEGACM_01565 1.9e-92 S Phosphoesterase
COOEGACM_01566 4.8e-105 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
COOEGACM_01567 3.4e-141 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
COOEGACM_01568 2.1e-97 yslB S Protein of unknown function (DUF2507)
COOEGACM_01569 5.1e-53 trxA O Belongs to the thioredoxin family
COOEGACM_01570 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
COOEGACM_01571 7.8e-86 cvpA S Colicin V production protein
COOEGACM_01572 6.1e-48 yrzB S Belongs to the UPF0473 family
COOEGACM_01573 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
COOEGACM_01574 4.1e-43 yrzL S Belongs to the UPF0297 family
COOEGACM_01575 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
COOEGACM_01576 1.1e-232 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
COOEGACM_01577 3.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
COOEGACM_01578 1.3e-30 yajC U Preprotein translocase
COOEGACM_01579 1.9e-192 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
COOEGACM_01580 1e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
COOEGACM_01581 8.7e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
COOEGACM_01582 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
COOEGACM_01583 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
COOEGACM_01584 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
COOEGACM_01585 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
COOEGACM_01586 3.1e-226 cinA 3.5.1.42 S Belongs to the CinA family
COOEGACM_01587 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
COOEGACM_01588 6.9e-139 ymfM S Helix-turn-helix domain
COOEGACM_01589 5.1e-248 ymfH S Peptidase M16
COOEGACM_01590 3e-229 ymfF S Peptidase M16 inactive domain protein
COOEGACM_01591 2.6e-160 aatB ET ABC transporter substrate-binding protein
COOEGACM_01592 2.1e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
COOEGACM_01593 4.2e-102 glnP P ABC transporter permease
COOEGACM_01594 8.7e-93 mreD M rod shape-determining protein MreD
COOEGACM_01595 5e-151 mreC M Involved in formation and maintenance of cell shape
COOEGACM_01596 1.7e-179 mreB D cell shape determining protein MreB
COOEGACM_01597 1.8e-121 radC L DNA repair protein
COOEGACM_01598 9.4e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
COOEGACM_01599 2.4e-231 ndh 1.6.99.3 C NADH dehydrogenase
COOEGACM_01600 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
COOEGACM_01601 1.8e-309 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
COOEGACM_01602 5.3e-184 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
COOEGACM_01603 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
COOEGACM_01604 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
COOEGACM_01605 8.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
COOEGACM_01606 1e-215 iscS2 2.8.1.7 E Aminotransferase class V
COOEGACM_01607 8.4e-251 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
COOEGACM_01608 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
COOEGACM_01609 7.4e-234 pbuG S permease
COOEGACM_01610 1.3e-259 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
COOEGACM_01611 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
COOEGACM_01612 1.9e-138 S Belongs to the UPF0246 family
COOEGACM_01613 2.5e-138 S Membrane
COOEGACM_01614 8.1e-75 4.4.1.5 E Glyoxalase
COOEGACM_01615 1.5e-21
COOEGACM_01616 2.7e-85 yueI S Protein of unknown function (DUF1694)
COOEGACM_01617 8.5e-243 rarA L recombination factor protein RarA
COOEGACM_01618 4.4e-46
COOEGACM_01619 1.3e-82 usp6 T universal stress protein
COOEGACM_01620 7.7e-205 araR K Transcriptional regulator
COOEGACM_01621 8.6e-156 ytbE 1.1.1.346 S Aldo keto reductase
COOEGACM_01622 4.7e-97 maa 2.3.1.79 S Maltose O-acetyltransferase
COOEGACM_01623 2.2e-284 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
COOEGACM_01624 3.7e-139 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
COOEGACM_01625 0.0 araB 2.7.1.16 G carbohydrate kinase FGGY
COOEGACM_01626 9.8e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
COOEGACM_01627 1.1e-147 2.3.1.19 K Helix-turn-helix XRE-family like proteins
COOEGACM_01628 6.9e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
COOEGACM_01629 1.4e-47 gcvH E glycine cleavage
COOEGACM_01630 1.1e-220 rodA D Belongs to the SEDS family
COOEGACM_01631 1e-31 S Protein of unknown function (DUF2969)
COOEGACM_01632 1.9e-178 mbl D Cell shape determining protein MreB Mrl
COOEGACM_01633 2.1e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
COOEGACM_01634 1.3e-33 ywzB S Protein of unknown function (DUF1146)
COOEGACM_01635 6.2e-294 L Transposase
COOEGACM_01636 1e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
COOEGACM_01637 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
COOEGACM_01638 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
COOEGACM_01639 1.5e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
COOEGACM_01640 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COOEGACM_01641 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
COOEGACM_01642 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COOEGACM_01643 4.7e-123 atpB C it plays a direct role in the translocation of protons across the membrane
COOEGACM_01644 5.9e-233 pyrP F Permease
COOEGACM_01645 2e-130 yibF S overlaps another CDS with the same product name
COOEGACM_01646 1.7e-191 yibE S overlaps another CDS with the same product name
COOEGACM_01647 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
COOEGACM_01648 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
COOEGACM_01649 3.2e-231 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
COOEGACM_01650 3.6e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
COOEGACM_01651 7.3e-166 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
COOEGACM_01652 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
COOEGACM_01653 6e-108 tdk 2.7.1.21 F thymidine kinase
COOEGACM_01654 3.4e-263 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
COOEGACM_01655 1.4e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
COOEGACM_01656 2.3e-10
COOEGACM_01657 1e-222 arcD U Amino acid permease
COOEGACM_01658 7.5e-261 E Arginine ornithine antiporter
COOEGACM_01659 2.7e-79 argR K Regulates arginine biosynthesis genes
COOEGACM_01660 3.5e-238 arcA 3.5.3.6 E Arginine
COOEGACM_01661 8.8e-187 ampC V Beta-lactamase
COOEGACM_01662 4.8e-20
COOEGACM_01663 0.0 M domain protein
COOEGACM_01664 5.3e-92
COOEGACM_01665 7.8e-263 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COOEGACM_01666 3.9e-132 L Belongs to the 'phage' integrase family
COOEGACM_01667 3.3e-11 dicA K Helix-turn-helix domain
COOEGACM_01668 2e-20 S Helix-turn-helix domain
COOEGACM_01671 2.5e-12
COOEGACM_01673 1.6e-47
COOEGACM_01674 5.2e-106 S D5 N terminal like
COOEGACM_01675 2.5e-13 arpU S Phage transcriptional regulator, ArpU family
COOEGACM_01683 3.6e-57
COOEGACM_01685 4.1e-86
COOEGACM_01686 0.0 copA 3.6.3.54 P P-type ATPase
COOEGACM_01687 2.4e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
COOEGACM_01688 7.9e-45 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
COOEGACM_01689 2.9e-102 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
COOEGACM_01690 3.6e-163 EG EamA-like transporter family
COOEGACM_01691 9.5e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
COOEGACM_01692 2.6e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
COOEGACM_01693 4.7e-154 KT YcbB domain
COOEGACM_01694 5.6e-32 xylB 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
COOEGACM_01696 5.1e-25
COOEGACM_01697 5e-262 pgi 5.3.1.9 G Belongs to the GPI family
COOEGACM_01698 8.4e-100 lacA 2.3.1.79 S Transferase hexapeptide repeat
COOEGACM_01699 2.8e-154 glcU U sugar transport
COOEGACM_01700 3.1e-273 yclK 2.7.13.3 T Histidine kinase
COOEGACM_01701 1.2e-134 K response regulator
COOEGACM_01703 1.8e-78 lytE M Lysin motif
COOEGACM_01704 3.2e-147 XK27_02985 S Cof-like hydrolase
COOEGACM_01705 1.8e-78 K Transcriptional regulator
COOEGACM_01706 0.0 oatA I Acyltransferase
COOEGACM_01707 1.6e-51
COOEGACM_01708 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
COOEGACM_01709 3.2e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
COOEGACM_01710 7.6e-126 ybbR S YbbR-like protein
COOEGACM_01711 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
COOEGACM_01712 8.2e-249 fucP G Major Facilitator Superfamily
COOEGACM_01713 3e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
COOEGACM_01714 2.7e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
COOEGACM_01715 3.6e-168 murB 1.3.1.98 M Cell wall formation
COOEGACM_01716 3e-101 dnaQ 2.7.7.7 L DNA polymerase III
COOEGACM_01717 1.4e-74 S PAS domain
COOEGACM_01718 6.1e-88 K Acetyltransferase (GNAT) domain
COOEGACM_01719 5.9e-82 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
COOEGACM_01720 4.9e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
COOEGACM_01721 1.8e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
COOEGACM_01722 6.3e-105 yxjI
COOEGACM_01723 5.5e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
COOEGACM_01724 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
COOEGACM_01725 6.1e-134 est 3.1.1.1 S Serine aminopeptidase, S33
COOEGACM_01726 1.8e-34 secG U Preprotein translocase
COOEGACM_01727 1.3e-293 clcA P chloride
COOEGACM_01728 1.6e-247 yifK E Amino acid permease
COOEGACM_01729 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
COOEGACM_01730 2e-140 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
COOEGACM_01731 1.2e-227 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
COOEGACM_01732 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
COOEGACM_01734 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
COOEGACM_01735 5.2e-259 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COOEGACM_01736 1.2e-206 glpT G Major Facilitator Superfamily
COOEGACM_01737 8.8e-15
COOEGACM_01739 3.1e-170 whiA K May be required for sporulation
COOEGACM_01740 6.5e-187 ybhK S Required for morphogenesis under gluconeogenic growth conditions
COOEGACM_01741 2.7e-160 rapZ S Displays ATPase and GTPase activities
COOEGACM_01742 2.4e-245 steT E amino acid
COOEGACM_01743 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
COOEGACM_01744 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
COOEGACM_01745 6.9e-14
COOEGACM_01746 1.9e-115 yfbR S HD containing hydrolase-like enzyme
COOEGACM_01747 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
COOEGACM_01748 7.2e-89 ykhA 3.1.2.20 I Thioesterase superfamily
COOEGACM_01749 1.9e-161 aatB ET PFAM extracellular solute-binding protein, family 3
COOEGACM_01750 3.4e-203 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
COOEGACM_01751 1.5e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
COOEGACM_01752 2.7e-168 lutA C Cysteine-rich domain
COOEGACM_01753 6e-293 lutB C 4Fe-4S dicluster domain
COOEGACM_01754 2.4e-138 yrjD S LUD domain
COOEGACM_01755 3.3e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
COOEGACM_01756 3.8e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
COOEGACM_01757 1e-156 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
COOEGACM_01758 4.6e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
COOEGACM_01759 6.4e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
COOEGACM_01760 3.1e-32 KT PspC domain protein
COOEGACM_01761 2.5e-186 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
COOEGACM_01762 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
COOEGACM_01763 4.5e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
COOEGACM_01764 1.4e-119 comFC S Competence protein
COOEGACM_01765 2.2e-246 comFA L Helicase C-terminal domain protein
COOEGACM_01766 1.2e-109 yvyE 3.4.13.9 S YigZ family
COOEGACM_01767 2e-37 EGP Major facilitator Superfamily
COOEGACM_01768 1.4e-156 EGP Major facilitator Superfamily
COOEGACM_01769 1.7e-67 rmaI K Transcriptional regulator
COOEGACM_01770 2.7e-39
COOEGACM_01771 0.0 ydaO E amino acid
COOEGACM_01772 2.8e-304 ybeC E amino acid
COOEGACM_01773 1e-60 S Aminoacyl-tRNA editing domain
COOEGACM_01774 5.5e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
COOEGACM_01775 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
COOEGACM_01776 6.9e-113 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
COOEGACM_01777 0.0 uup S ABC transporter, ATP-binding protein
COOEGACM_01778 3e-262 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COOEGACM_01779 7.3e-183 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
COOEGACM_01780 1.5e-227 mtnE 2.6.1.83 E Aminotransferase
COOEGACM_01781 5.1e-142 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
COOEGACM_01782 2.9e-137 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
COOEGACM_01783 1.1e-226 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
COOEGACM_01784 2.1e-132 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
COOEGACM_01785 1.2e-196 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
COOEGACM_01786 4.3e-103 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
COOEGACM_01787 7.3e-127 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
COOEGACM_01788 2.5e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
COOEGACM_01789 8.1e-174 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
COOEGACM_01790 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
COOEGACM_01791 2e-280 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
COOEGACM_01792 1.1e-136 fat 3.1.2.21 I Acyl-ACP thioesterase
COOEGACM_01793 1.5e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
COOEGACM_01794 1.6e-58 yabA L Involved in initiation control of chromosome replication
COOEGACM_01795 1.5e-186 holB 2.7.7.7 L DNA polymerase III
COOEGACM_01796 1e-51 yaaQ S Cyclic-di-AMP receptor
COOEGACM_01797 1.5e-115 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
COOEGACM_01798 9.7e-39 S Protein of unknown function (DUF2508)
COOEGACM_01799 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
COOEGACM_01800 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
COOEGACM_01801 4.9e-305 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
COOEGACM_01802 3.5e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
COOEGACM_01803 3.4e-35 nrdH O Glutaredoxin
COOEGACM_01804 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COOEGACM_01805 3.4e-199 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COOEGACM_01806 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
COOEGACM_01807 1.1e-136 S Putative adhesin
COOEGACM_01808 2.4e-78 XK27_06920 S Protein of unknown function (DUF1700)
COOEGACM_01809 6.8e-56 K transcriptional regulator PadR family
COOEGACM_01810 7.7e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
COOEGACM_01812 3.4e-48
COOEGACM_01813 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
COOEGACM_01814 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
COOEGACM_01815 6.9e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
COOEGACM_01816 2.9e-243 M Glycosyl transferase family group 2
COOEGACM_01818 1.3e-226 aadAT EK Aminotransferase, class I
COOEGACM_01819 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
COOEGACM_01820 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
COOEGACM_01821 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
COOEGACM_01822 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
COOEGACM_01823 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
COOEGACM_01824 3e-136 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COOEGACM_01825 2.1e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
COOEGACM_01826 1.9e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
COOEGACM_01827 9.5e-206 yacL S domain protein
COOEGACM_01828 7.8e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
COOEGACM_01829 1.6e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
COOEGACM_01830 3.8e-50 HA62_12640 S GCN5-related N-acetyl-transferase
COOEGACM_01831 8.4e-125 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
COOEGACM_01832 1.7e-267 pepC 3.4.22.40 E Peptidase C1-like family
COOEGACM_01833 2.1e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
COOEGACM_01834 3.1e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
COOEGACM_01835 5.4e-119 tcyB E ABC transporter
COOEGACM_01836 3e-212 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
COOEGACM_01837 5.9e-168 I alpha/beta hydrolase fold
COOEGACM_01838 1.2e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
COOEGACM_01839 0.0 S Bacterial membrane protein, YfhO
COOEGACM_01840 4.2e-183 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
COOEGACM_01841 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
COOEGACM_01843 1.1e-83 ydcK S Belongs to the SprT family
COOEGACM_01844 0.0 yhgF K Tex-like protein N-terminal domain protein
COOEGACM_01845 1.5e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
COOEGACM_01846 4.2e-283 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
COOEGACM_01847 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
COOEGACM_01848 8.8e-133 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
COOEGACM_01849 2.2e-301 aspT P Predicted Permease Membrane Region
COOEGACM_01850 4.5e-250 EGP Major facilitator Superfamily
COOEGACM_01851 1.8e-108
COOEGACM_01854 2.2e-148 yjjH S Calcineurin-like phosphoesterase
COOEGACM_01855 1e-263 dtpT U amino acid peptide transporter
COOEGACM_01856 3.7e-19
COOEGACM_01858 2.2e-14 K Cro/C1-type HTH DNA-binding domain
COOEGACM_01859 4.6e-79 L PFAM transposase IS200-family protein
COOEGACM_01860 1.2e-79
COOEGACM_01861 3e-113 M Lysin motif
COOEGACM_01862 5.8e-195 EGP Major facilitator Superfamily
COOEGACM_01863 9.9e-103 ywlG S Belongs to the UPF0340 family
COOEGACM_01864 3e-159 spoU 2.1.1.185 J Methyltransferase
COOEGACM_01865 6.4e-224 oxlT P Major Facilitator Superfamily
COOEGACM_01866 1.6e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
COOEGACM_01868 3.4e-222 S cog cog1373
COOEGACM_01869 1.7e-176 coaA 2.7.1.33 F Pantothenic acid kinase
COOEGACM_01870 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
COOEGACM_01871 1.6e-160 EG EamA-like transporter family
COOEGACM_01872 7.8e-263 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COOEGACM_01873 1e-254 nox C NADH oxidase
COOEGACM_01874 1.9e-250 nox C NADH oxidase
COOEGACM_01875 0.0 helD 3.6.4.12 L DNA helicase
COOEGACM_01876 3.4e-115 dedA S SNARE associated Golgi protein
COOEGACM_01877 5e-127 3.1.3.73 G phosphoglycerate mutase
COOEGACM_01878 5.4e-226 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
COOEGACM_01879 9e-10
COOEGACM_01880 4.4e-31 S Transglycosylase associated protein
COOEGACM_01882 2e-180 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COOEGACM_01883 3.5e-233 V domain protein
COOEGACM_01884 3.5e-94 K Transcriptional regulator (TetR family)
COOEGACM_01885 2.9e-38 pspC KT PspC domain protein
COOEGACM_01886 9.9e-152
COOEGACM_01887 1.2e-16 3.2.1.14 GH18
COOEGACM_01888 1.5e-82 zur P Belongs to the Fur family
COOEGACM_01889 2.4e-101 gmk2 2.7.4.8 F Guanylate kinase
COOEGACM_01890 4.9e-72 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
COOEGACM_01891 1.5e-253 yfnA E Amino Acid
COOEGACM_01892 5e-227 EGP Sugar (and other) transporter
COOEGACM_01893 1.7e-227
COOEGACM_01894 1.6e-207 potD P ABC transporter
COOEGACM_01895 1.9e-139 potC P ABC transporter permease
COOEGACM_01896 2.9e-145 potB P ABC transporter permease
COOEGACM_01897 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
COOEGACM_01898 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
COOEGACM_01899 1.5e-177 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
COOEGACM_01900 0.0 pacL 3.6.3.8 P P-type ATPase
COOEGACM_01901 2.6e-85 dps P Belongs to the Dps family
COOEGACM_01902 2.1e-255 yagE E amino acid
COOEGACM_01903 8.8e-116 gph 3.1.3.18 S HAD hydrolase, family IA, variant
COOEGACM_01904 5.5e-150 3.6.4.12 S PD-(D/E)XK nuclease family transposase
COOEGACM_01906 1.5e-24 S Domain of unknown function (DUF4767)
COOEGACM_01908 3.2e-181 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
COOEGACM_01909 3e-181 iunH2 3.2.2.1 F nucleoside hydrolase
COOEGACM_01910 2.1e-137 IQ KR domain
COOEGACM_01911 3.3e-133 S membrane transporter protein
COOEGACM_01912 2.1e-97 S ABC-type cobalt transport system, permease component
COOEGACM_01913 1.5e-250 cbiO1 S ABC transporter, ATP-binding protein
COOEGACM_01914 7.5e-115 P Cobalt transport protein
COOEGACM_01915 4.7e-52 yvlA
COOEGACM_01916 0.0 yjcE P Sodium proton antiporter
COOEGACM_01917 1.1e-51 ypaA S Protein of unknown function (DUF1304)
COOEGACM_01918 4.8e-190 D Alpha beta
COOEGACM_01919 1e-72 K Transcriptional regulator
COOEGACM_01920 2.2e-159
COOEGACM_01921 1.1e-133 1.6.5.5 C Zinc-binding dehydrogenase
COOEGACM_01922 5e-33 1.6.5.5 C Zinc-binding dehydrogenase
COOEGACM_01923 6.5e-257 G PTS system Galactitol-specific IIC component
COOEGACM_01924 3.1e-212 EGP Major facilitator Superfamily
COOEGACM_01925 9.6e-35 V ABC transporter
COOEGACM_01926 1.1e-250 L PFAM transposase, IS4 family protein
COOEGACM_01927 2.5e-91 V ABC transporter
COOEGACM_01928 3.7e-107
COOEGACM_01929 5.2e-14
COOEGACM_01930 7.1e-63
COOEGACM_01931 3.9e-195 lplA 6.3.1.20 H Lipoate-protein ligase
COOEGACM_01932 5.1e-81 uspA T universal stress protein
COOEGACM_01933 0.0 tetP J elongation factor G
COOEGACM_01934 3.1e-167 GK ROK family
COOEGACM_01935 1.5e-242 brnQ U Component of the transport system for branched-chain amino acids
COOEGACM_01936 8.5e-139 aroD S Serine hydrolase (FSH1)
COOEGACM_01937 4.7e-244 yagE E amino acid
COOEGACM_01938 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
COOEGACM_01939 1.6e-134 gntR K UbiC transcription regulator-associated domain protein
COOEGACM_01940 1e-87 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
COOEGACM_01941 1.1e-283 pipD E Dipeptidase
COOEGACM_01942 0.0 yfiC V ABC transporter
COOEGACM_01943 1e-304 lmrA V ABC transporter, ATP-binding protein
COOEGACM_01944 2.4e-189 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COOEGACM_01945 5.4e-135 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
COOEGACM_01946 5.1e-154
COOEGACM_01947 1.3e-156 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
COOEGACM_01948 1.3e-172 S AI-2E family transporter
COOEGACM_01949 3.4e-132 XK27_07210 6.1.1.6 S B3 4 domain
COOEGACM_01950 8.7e-78 yybA 2.3.1.57 K Transcriptional regulator
COOEGACM_01951 3.6e-91 M1-874 K Domain of unknown function (DUF1836)
COOEGACM_01952 3.9e-90 1.14.14.47, 1.6.5.3, 1.6.99.3 GM epimerase
COOEGACM_01953 3.5e-152 ypdB V (ABC) transporter
COOEGACM_01954 2.3e-240 yhdP S Transporter associated domain
COOEGACM_01955 1.3e-84 nrdI F Belongs to the NrdI family
COOEGACM_01956 3.5e-64 S 3-demethylubiquinone-9 3-methyltransferase
COOEGACM_01957 1.7e-191 yeaN P Transporter, major facilitator family protein
COOEGACM_01958 7.5e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
COOEGACM_01959 5.4e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
COOEGACM_01960 7.8e-263 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COOEGACM_01961 2.7e-39
COOEGACM_01962 1.4e-286 lacS G Transporter
COOEGACM_01963 6.2e-79 uspA T universal stress protein
COOEGACM_01964 3.7e-79 K AsnC family
COOEGACM_01965 7.8e-263 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COOEGACM_01966 1.6e-228 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
COOEGACM_01967 8.6e-97 dedA 3.1.3.1 S SNARE associated Golgi protein
COOEGACM_01968 1.8e-181 galR K Transcriptional regulator
COOEGACM_01969 7.1e-283 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
COOEGACM_01970 5e-226 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
COOEGACM_01971 7.6e-180 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
COOEGACM_01972 1.4e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
COOEGACM_01973 3.1e-92 yxkA S Phosphatidylethanolamine-binding protein
COOEGACM_01974 9.1e-36
COOEGACM_01975 3.5e-52
COOEGACM_01976 4.3e-203
COOEGACM_01977 9.8e-83 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
COOEGACM_01978 1.2e-135 pnuC H nicotinamide mononucleotide transporter
COOEGACM_01979 1.1e-155 ytbE 1.1.1.346 S Aldo keto reductase
COOEGACM_01980 6.4e-125 K response regulator
COOEGACM_01981 4.8e-182 T PhoQ Sensor
COOEGACM_01982 5.4e-133 macB2 V ABC transporter, ATP-binding protein
COOEGACM_01983 0.0 ysaB V FtsX-like permease family
COOEGACM_01984 2e-157 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
COOEGACM_01985 1.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
COOEGACM_01986 3.6e-54 K helix_turn_helix, mercury resistance
COOEGACM_01987 1.9e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COOEGACM_01988 5.3e-196 EGP Major facilitator Superfamily
COOEGACM_01989 7.1e-89 ymdB S Macro domain protein
COOEGACM_01990 1.7e-111 K Helix-turn-helix domain
COOEGACM_01991 0.0 pepO 3.4.24.71 O Peptidase family M13
COOEGACM_01992 3.6e-48
COOEGACM_01993 3e-232 S Putative metallopeptidase domain
COOEGACM_01994 1.5e-206 3.1.3.1 S associated with various cellular activities
COOEGACM_01995 2.8e-119 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
COOEGACM_01996 5.8e-64 yeaO S Protein of unknown function, DUF488
COOEGACM_01998 2e-118 yrkL S Flavodoxin-like fold
COOEGACM_01999 4e-53
COOEGACM_02000 1.3e-17 S Domain of unknown function (DUF4767)
COOEGACM_02001 8.8e-136 3.6.4.12 S PD-(D/E)XK nuclease family transposase
COOEGACM_02002 1.1e-49
COOEGACM_02003 8.9e-206 nrnB S DHHA1 domain
COOEGACM_02004 2e-230 S Uncharacterized protein conserved in bacteria (DUF2325)
COOEGACM_02005 5.4e-248 brnQ U Component of the transport system for branched-chain amino acids
COOEGACM_02006 2.2e-105 NU mannosyl-glycoprotein
COOEGACM_02007 9.8e-146 S Putative ABC-transporter type IV
COOEGACM_02008 5.4e-273 S ABC transporter, ATP-binding protein
COOEGACM_02010 1.2e-07 S HTH domain
COOEGACM_02011 1.1e-34 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
COOEGACM_02012 1.4e-179 arsB 1.20.4.1 P Sodium Bile acid symporter family
COOEGACM_02013 2.9e-69 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
COOEGACM_02014 1.9e-56 cadX K Bacterial regulatory protein, arsR family
COOEGACM_02015 2.8e-95 cadD P Cadmium resistance transporter
COOEGACM_02016 4.6e-24 K Helix-turn-helix domain
COOEGACM_02017 6.7e-31 WQ51_00220 K Helix-turn-helix domain
COOEGACM_02018 1.1e-102 S Protein of unknown function (DUF3278)
COOEGACM_02019 1.8e-08
COOEGACM_02020 7.2e-72 M PFAM NLP P60 protein
COOEGACM_02021 2.9e-182 ABC-SBP S ABC transporter
COOEGACM_02022 1.1e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
COOEGACM_02023 4.8e-137 XK27_08845 S ABC transporter, ATP-binding protein
COOEGACM_02024 2.2e-94 P Cadmium resistance transporter
COOEGACM_02025 8.9e-56 K Transcriptional regulator, ArsR family
COOEGACM_02026 2.4e-237 mepA V MATE efflux family protein
COOEGACM_02027 2.1e-54 trxA O Belongs to the thioredoxin family
COOEGACM_02028 2.3e-131 terC P membrane
COOEGACM_02029 5.3e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
COOEGACM_02030 1.5e-166 corA P CorA-like Mg2+ transporter protein
COOEGACM_02031 3.2e-283 pipD E Dipeptidase
COOEGACM_02032 1.2e-241 pbuX F xanthine permease
COOEGACM_02033 1.1e-248 nhaC C Na H antiporter NhaC
COOEGACM_02034 5.8e-283 S C4-dicarboxylate anaerobic carrier
COOEGACM_02035 5.5e-126 pgm3 3.1.3.73 G phosphoglycerate mutase family
COOEGACM_02036 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
COOEGACM_02037 3.2e-206 gldA 1.1.1.6 C dehydrogenase
COOEGACM_02038 4e-124 S Alpha beta hydrolase
COOEGACM_02039 1.6e-216 dacA 3.4.16.4 M Belongs to the peptidase S11 family
COOEGACM_02040 2.7e-100
COOEGACM_02042 1.2e-123 yciB M ErfK YbiS YcfS YnhG
COOEGACM_02043 8.1e-260 S Putative peptidoglycan binding domain
COOEGACM_02044 9.3e-110 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
COOEGACM_02045 3.5e-88
COOEGACM_02046 3.4e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
COOEGACM_02047 1.2e-216 yttB EGP Major facilitator Superfamily
COOEGACM_02048 6.3e-103
COOEGACM_02049 1e-24
COOEGACM_02050 5.5e-175 scrR K Transcriptional regulator, LacI family
COOEGACM_02051 1.5e-239 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
COOEGACM_02052 4.1e-50 czrA K Transcriptional regulator, ArsR family
COOEGACM_02053 7.3e-36
COOEGACM_02054 0.0 yhcA V ABC transporter, ATP-binding protein
COOEGACM_02055 2.6e-118 devA 3.6.3.25 V ABC transporter, ATP-binding protein
COOEGACM_02056 2.2e-172 hrtB V ABC transporter permease
COOEGACM_02057 5.5e-89 ygfC K transcriptional regulator (TetR family)
COOEGACM_02058 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
COOEGACM_02059 1e-290 mntH P H( )-stimulated, divalent metal cation uptake system
COOEGACM_02060 7.8e-30
COOEGACM_02061 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
COOEGACM_02063 4.3e-228 yxiO S Vacuole effluxer Atg22 like
COOEGACM_02064 1.2e-254 npp S type I phosphodiesterase nucleotide pyrophosphatase
COOEGACM_02065 2.9e-241 E amino acid
COOEGACM_02066 6.7e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
COOEGACM_02068 3.3e-211 yxjG_1 E methionine synthase, vitamin-B12 independent
COOEGACM_02069 1.6e-41 S Cytochrome B5
COOEGACM_02070 5.4e-09 S Cytochrome B5
COOEGACM_02071 1.8e-39 S Cytochrome B5
COOEGACM_02072 7.8e-76 elaA S Gnat family
COOEGACM_02073 1.4e-121 GM NmrA-like family
COOEGACM_02074 2.8e-51 hxlR K Transcriptional regulator, HxlR family
COOEGACM_02075 5.7e-109 XK27_02070 S Nitroreductase family
COOEGACM_02076 1.2e-82 K Transcriptional regulator, HxlR family
COOEGACM_02077 1.6e-228
COOEGACM_02078 3.8e-210 EGP Major facilitator Superfamily
COOEGACM_02079 1.4e-256 pepC 3.4.22.40 E aminopeptidase
COOEGACM_02080 9.9e-112 ylbE GM NAD dependent epimerase dehydratase family protein
COOEGACM_02081 0.0 pepN 3.4.11.2 E aminopeptidase
COOEGACM_02082 1.2e-92 folT S ECF transporter, substrate-specific component
COOEGACM_02083 4.9e-198 asnA 6.3.1.1 F aspartate--ammonia ligase
COOEGACM_02084 1.3e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
COOEGACM_02085 1.4e-113 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
COOEGACM_02086 7.1e-201 2.7.7.65 T GGDEF domain
COOEGACM_02087 2.1e-128 yfeJ 6.3.5.2 F glutamine amidotransferase
COOEGACM_02088 8.2e-63 yneR
COOEGACM_02089 2.5e-110 GM NAD(P)H-binding
COOEGACM_02090 1.1e-185 S membrane
COOEGACM_02091 6.9e-104 K Transcriptional regulator C-terminal region
COOEGACM_02092 1.9e-158 akr5f 1.1.1.346 S reductase
COOEGACM_02093 3.7e-133 K Transcriptional regulator
COOEGACM_02094 5.2e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
COOEGACM_02095 3e-155 ypuA S Protein of unknown function (DUF1002)
COOEGACM_02096 1.1e-228 aadAT EK Aminotransferase, class I
COOEGACM_02097 3.8e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
COOEGACM_02098 1.3e-153 tesE Q hydratase
COOEGACM_02099 1.2e-129 S Alpha beta hydrolase
COOEGACM_02100 4.5e-82 lacA S transferase hexapeptide repeat
COOEGACM_02101 3.7e-35 K Transcriptional regulator
COOEGACM_02102 1.9e-83 C Flavodoxin
COOEGACM_02103 8.3e-11 S Oxidoreductase, aldo keto reductase family protein
COOEGACM_02105 2.4e-34 yphJ 4.1.1.44 S decarboxylase
COOEGACM_02106 9.9e-09 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
COOEGACM_02107 3.3e-114 P nitric oxide dioxygenase activity
COOEGACM_02108 1.2e-107 S Peptidase propeptide and YPEB domain
COOEGACM_02109 2.1e-233 T GHKL domain
COOEGACM_02110 1.8e-119 T Transcriptional regulatory protein, C terminal
COOEGACM_02111 4e-162 mleP3 S Membrane transport protein
COOEGACM_02112 2.6e-118 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
COOEGACM_02116 8.3e-203 2.7.13.3 T GHKL domain
COOEGACM_02117 1.3e-113 K LytTr DNA-binding domain
COOEGACM_02118 4.7e-176 L transposase, IS605 OrfB family
COOEGACM_02119 4.9e-66 L Transposase IS200 like
COOEGACM_02120 3.9e-26 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
COOEGACM_02121 1e-24
COOEGACM_02122 1.2e-19 relB L Addiction module antitoxin, RelB DinJ family
COOEGACM_02123 1.9e-86 XK27_08850 J Aminoacyl-tRNA editing domain
COOEGACM_02124 6.5e-64 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
COOEGACM_02125 1.3e-195 V Beta-lactamase
COOEGACM_02126 1.6e-94 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
COOEGACM_02127 4.5e-123 yhiD S MgtC family
COOEGACM_02129 1.1e-113 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
COOEGACM_02130 9.3e-43 azlD E Branched-chain amino acid transport
COOEGACM_02131 1.2e-08
COOEGACM_02132 1.4e-34 CP ABC-2 family transporter protein
COOEGACM_02133 4.3e-83 V ABC transporter, ATP-binding protein
COOEGACM_02134 5.6e-41 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
COOEGACM_02135 4.3e-302 S amidohydrolase
COOEGACM_02136 1.2e-165 S reductase
COOEGACM_02137 8e-93 2.3.1.183 M Acetyltransferase GNAT family
COOEGACM_02138 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
COOEGACM_02139 6.4e-248 yxbA 6.3.1.12 S ATP-grasp enzyme
COOEGACM_02140 1.1e-294 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
COOEGACM_02141 0.0 asnB 6.3.5.4 E Asparagine synthase
COOEGACM_02142 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
COOEGACM_02143 7.3e-253 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
COOEGACM_02144 2.1e-132 jag S R3H domain protein
COOEGACM_02145 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
COOEGACM_02146 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
COOEGACM_02147 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
COOEGACM_02148 0.0 3.1.21.3 V Type II restriction enzyme, methylase subunits
COOEGACM_02150 1.7e-35
COOEGACM_02152 2.7e-72 D CobQ CobB MinD ParA nucleotide binding domain protein
COOEGACM_02154 9.8e-84
COOEGACM_02157 7.4e-153 U TraM recognition site of TraD and TraG
COOEGACM_02162 1.2e-300 L Transposase
COOEGACM_02163 1.6e-23 L transposase, IS605 OrfB family
COOEGACM_02165 4.8e-39
COOEGACM_02168 4e-61 M CHAP domain
COOEGACM_02172 1.9e-147 S regulation of response to stimulus
COOEGACM_02173 2.8e-10 L Resolvase, N-terminal
COOEGACM_02175 9e-72 endA F DNA RNA non-specific endonuclease
COOEGACM_02176 9.1e-61 L Initiator Replication protein
COOEGACM_02177 4.7e-176 L transposase, IS605 OrfB family
COOEGACM_02178 4.9e-66 L Transposase IS200 like
COOEGACM_02179 2.5e-36 S Uncharacterized protein conserved in bacteria (DUF2325)
COOEGACM_02180 4e-167 S membrane
COOEGACM_02181 1.6e-145 V TaqI-like C-terminal specificity domain
COOEGACM_02182 5.7e-32 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
COOEGACM_02183 1.5e-17 chpR T PFAM SpoVT AbrB
COOEGACM_02184 1.9e-16 K prlF antitoxin for toxin YhaV_toxin
COOEGACM_02185 5.5e-32 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
COOEGACM_02187 2.4e-95 htpX O Peptidase family M48
COOEGACM_02197 7.5e-77 traI 5.99.1.2 L DNA topoisomerase
COOEGACM_02198 4.5e-15 xlyB 3.5.1.28 CBM50 M LysM domain
COOEGACM_02199 1.6e-42 xerD L Phage integrase, N-terminal SAM-like domain
COOEGACM_02204 1.2e-300 L Transposase
COOEGACM_02207 3.6e-60 fhaB M Rib/alpha-like repeat
COOEGACM_02208 1.4e-46 atl 3.2.1.96, 3.5.1.28 GH73 UW LPXTG-motif cell wall anchor domain protein
COOEGACM_02209 1.2e-300 L Transposase
COOEGACM_02213 1.3e-35 CBM50 M NlpC P60 family protein
COOEGACM_02218 1.4e-267 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
COOEGACM_02220 1.7e-123 U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
COOEGACM_02224 1.1e-161 M MucBP domain
COOEGACM_02225 1.1e-15
COOEGACM_02226 1.1e-15
COOEGACM_02227 4e-30
COOEGACM_02228 3.6e-75 K Putative DNA-binding domain
COOEGACM_02229 1.5e-101 ypuA S Protein of unknown function (DUF1002)
COOEGACM_02231 1.2e-85 L Integrase
COOEGACM_02232 1.5e-35
COOEGACM_02234 8.5e-64 V HNH endonuclease
COOEGACM_02235 1.8e-07 yokH G SMI1 / KNR4 family (SUKH-1)
COOEGACM_02240 7.4e-19 ybjQ S Belongs to the UPF0145 family
COOEGACM_02246 2.3e-240 L Transposase
COOEGACM_02247 1.8e-38 sip M LysM domain protein
COOEGACM_02249 2.5e-120 xerS L Belongs to the 'phage' integrase family
COOEGACM_02250 4.5e-241 L Transposase
COOEGACM_02251 4.9e-66 L Transposase IS200 like
COOEGACM_02252 4.7e-176 L transposase, IS605 OrfB family
COOEGACM_02254 1.6e-11 nrdH O Glutaredoxin
COOEGACM_02255 9.9e-20 3.6.4.12 S PD-(D/E)XK nuclease family transposase
COOEGACM_02256 7.1e-14 3.6.4.12 S Psort location Cytoplasmic, score 8.87
COOEGACM_02257 3.5e-11
COOEGACM_02259 2e-124 1.6.5.2 GM NAD(P)H-binding
COOEGACM_02260 3.4e-132 1.6.5.2 GM NAD(P)H-binding
COOEGACM_02261 1.6e-13 QT PucR C-terminal helix-turn-helix domain
COOEGACM_02264 4.7e-176 L transposase, IS605 OrfB family
COOEGACM_02265 4.9e-66 L Transposase IS200 like
COOEGACM_02267 3.8e-101
COOEGACM_02268 4e-296 U Psort location Cytoplasmic, score
COOEGACM_02270 3.6e-108
COOEGACM_02276 9.3e-14
COOEGACM_02277 3.1e-17
COOEGACM_02278 5.3e-21
COOEGACM_02279 4e-17 relB L Addiction module antitoxin, RelB DinJ family
COOEGACM_02284 2e-54
COOEGACM_02285 4.7e-176 L transposase, IS605 OrfB family
COOEGACM_02286 4.9e-66 L Transposase IS200 like
COOEGACM_02287 1.8e-40
COOEGACM_02288 4e-38 K Antidote-toxin recognition MazE, bacterial antitoxin
COOEGACM_02289 2.3e-09 3.6.4.12 S PD-(D/E)XK nuclease family transposase
COOEGACM_02290 8e-52 S protein conserved in bacteria
COOEGACM_02292 2.6e-78 S Fic/DOC family
COOEGACM_02298 2.2e-09 ard S Antirestriction protein (ArdA)
COOEGACM_02303 1.4e-29 dnaG L DNA primase activity
COOEGACM_02304 5.4e-13
COOEGACM_02305 2.3e-240 L Transposase
COOEGACM_02306 4.7e-176 L transposase, IS605 OrfB family
COOEGACM_02307 4.9e-66 L Transposase IS200 like
COOEGACM_02313 1.4e-81
COOEGACM_02314 1.7e-14 ispH 1.17.7.4 J negative regulation of cytoplasmic translation
COOEGACM_02315 2.1e-131 3.2.1.97 GH101 M Psort location Cellwall, score
COOEGACM_02316 0.0 L helicase superfamily c-terminal domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)