ORF_ID e_value Gene_name EC_number CAZy COGs Description
JHKNLHEE_00001 1.8e-27 spoVAE S stage V sporulation protein
JHKNLHEE_00004 1.3e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
JHKNLHEE_00005 1.3e-287 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
JHKNLHEE_00006 1e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
JHKNLHEE_00008 1.8e-98 yqjB S protein conserved in bacteria
JHKNLHEE_00009 3.3e-175 yqjA S Putative aromatic acid exporter C-terminal domain
JHKNLHEE_00010 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
JHKNLHEE_00011 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
JHKNLHEE_00012 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
JHKNLHEE_00013 6e-76 yqiW S Belongs to the UPF0403 family
JHKNLHEE_00014 3.7e-165 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
JHKNLHEE_00015 7.9e-208 norA EGP Major facilitator Superfamily
JHKNLHEE_00016 4.4e-152 bmrR K helix_turn_helix, mercury resistance
JHKNLHEE_00017 4.4e-228 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
JHKNLHEE_00018 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
JHKNLHEE_00019 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
JHKNLHEE_00020 1.1e-267 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
JHKNLHEE_00021 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
JHKNLHEE_00022 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
JHKNLHEE_00023 1e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
JHKNLHEE_00024 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
JHKNLHEE_00025 4e-34 yqzF S Protein of unknown function (DUF2627)
JHKNLHEE_00026 8.7e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JHKNLHEE_00027 8.2e-276 prpD 4.2.1.79 S 2-methylcitrate dehydratase
JHKNLHEE_00028 8.1e-210 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
JHKNLHEE_00029 6.7e-212 mmgC I acyl-CoA dehydrogenase
JHKNLHEE_00030 2.6e-155 hbdA 1.1.1.157 I Dehydrogenase
JHKNLHEE_00031 1.3e-218 mmgA 2.3.1.9 I Belongs to the thiolase family
JHKNLHEE_00032 2.3e-128 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
JHKNLHEE_00033 8.6e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
JHKNLHEE_00034 1.5e-25
JHKNLHEE_00036 4.7e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
JHKNLHEE_00038 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
JHKNLHEE_00039 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
JHKNLHEE_00040 3.2e-306 recN L May be involved in recombinational repair of damaged DNA
JHKNLHEE_00041 1.7e-78 argR K Regulates arginine biosynthesis genes
JHKNLHEE_00042 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
JHKNLHEE_00043 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JHKNLHEE_00044 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
JHKNLHEE_00045 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
JHKNLHEE_00046 1.9e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
JHKNLHEE_00047 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JHKNLHEE_00048 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JHKNLHEE_00049 2.1e-67 yqhY S protein conserved in bacteria
JHKNLHEE_00050 5.9e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
JHKNLHEE_00051 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
JHKNLHEE_00052 2.9e-90 spoIIIAH S SpoIIIAH-like protein
JHKNLHEE_00053 2.2e-109 spoIIIAG S stage III sporulation protein AG
JHKNLHEE_00054 1.2e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
JHKNLHEE_00055 1.3e-197 spoIIIAE S stage III sporulation protein AE
JHKNLHEE_00056 2.3e-58 spoIIIAD S Stage III sporulation protein AD
JHKNLHEE_00057 7.6e-29 spoIIIAC S stage III sporulation protein AC
JHKNLHEE_00058 1.1e-84 spoIIIAB S Stage III sporulation protein
JHKNLHEE_00059 4e-170 spoIIIAA S stage III sporulation protein AA
JHKNLHEE_00060 7.9e-37 yqhV S Protein of unknown function (DUF2619)
JHKNLHEE_00061 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JHKNLHEE_00062 4.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
JHKNLHEE_00063 1.6e-76 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
JHKNLHEE_00064 6.6e-93 yqhR S Conserved membrane protein YqhR
JHKNLHEE_00065 2.3e-173 yqhQ S Protein of unknown function (DUF1385)
JHKNLHEE_00066 2.8e-48 yqhP
JHKNLHEE_00067 9e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
JHKNLHEE_00068 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
JHKNLHEE_00069 1.3e-159 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
JHKNLHEE_00070 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
JHKNLHEE_00071 3.7e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JHKNLHEE_00072 2.2e-254 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JHKNLHEE_00073 5.3e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
JHKNLHEE_00074 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
JHKNLHEE_00075 1.6e-151 yqhG S Bacterial protein YqhG of unknown function
JHKNLHEE_00076 1.2e-24 sinI S Anti-repressor SinI
JHKNLHEE_00077 1e-54 sinR K transcriptional
JHKNLHEE_00078 4.3e-141 tasA S Cell division protein FtsN
JHKNLHEE_00079 2.1e-57 sipW 3.4.21.89 U Signal peptidase
JHKNLHEE_00080 4.8e-97 yqxM
JHKNLHEE_00081 2.8e-53 yqzG S Protein of unknown function (DUF3889)
JHKNLHEE_00082 5.2e-26 yqzE S YqzE-like protein
JHKNLHEE_00083 2e-43 S ComG operon protein 7
JHKNLHEE_00084 6e-45 comGF U Putative Competence protein ComGF
JHKNLHEE_00085 1.3e-57 comGE
JHKNLHEE_00086 4.1e-69 gspH NU protein transport across the cell outer membrane
JHKNLHEE_00087 1.2e-46 comGC U Required for transformation and DNA binding
JHKNLHEE_00088 1.4e-168 comGB NU COG1459 Type II secretory pathway, component PulF
JHKNLHEE_00089 5e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JHKNLHEE_00090 6.7e-173 corA P Mg2 transporter protein
JHKNLHEE_00091 2.2e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
JHKNLHEE_00092 1.5e-147 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
JHKNLHEE_00094 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
JHKNLHEE_00095 2e-36 yqgY S Protein of unknown function (DUF2626)
JHKNLHEE_00096 2.1e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
JHKNLHEE_00097 8.9e-23 yqgW S Protein of unknown function (DUF2759)
JHKNLHEE_00098 6.9e-50 yqgV S Thiamine-binding protein
JHKNLHEE_00099 1.4e-198 yqgU
JHKNLHEE_00100 3.3e-219 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
JHKNLHEE_00101 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
JHKNLHEE_00102 1.5e-180 glcK 2.7.1.2 G Glucokinase
JHKNLHEE_00103 4.7e-32 yqgQ S Protein conserved in bacteria
JHKNLHEE_00104 4e-260 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
JHKNLHEE_00105 2.5e-09 yqgO
JHKNLHEE_00106 1.4e-101 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JHKNLHEE_00107 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
JHKNLHEE_00108 2.8e-199 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
JHKNLHEE_00110 3.5e-50 yqzD
JHKNLHEE_00111 7.3e-72 yqzC S YceG-like family
JHKNLHEE_00112 1.4e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JHKNLHEE_00113 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JHKNLHEE_00114 1.3e-157 pstA P Phosphate transport system permease
JHKNLHEE_00115 9.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
JHKNLHEE_00116 2e-150 pstS P Phosphate
JHKNLHEE_00117 0.0 pbpA 3.4.16.4 M penicillin-binding protein
JHKNLHEE_00118 4e-229 yqgE EGP Major facilitator superfamily
JHKNLHEE_00119 3.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
JHKNLHEE_00120 4e-73 yqgC S protein conserved in bacteria
JHKNLHEE_00121 3.9e-131 yqgB S Protein of unknown function (DUF1189)
JHKNLHEE_00122 4.4e-46 yqfZ M LysM domain
JHKNLHEE_00123 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JHKNLHEE_00124 3.7e-61 yqfX S membrane
JHKNLHEE_00125 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
JHKNLHEE_00126 1.9e-77 zur P Belongs to the Fur family
JHKNLHEE_00127 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
JHKNLHEE_00128 2.1e-36 yqfT S Protein of unknown function (DUF2624)
JHKNLHEE_00129 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JHKNLHEE_00130 8.5e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
JHKNLHEE_00132 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JHKNLHEE_00133 5.6e-134 M Membrane
JHKNLHEE_00134 2.4e-30 yetM CH FAD binding domain
JHKNLHEE_00135 9.1e-105 yetJ S Belongs to the BI1 family
JHKNLHEE_00136 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
JHKNLHEE_00137 2.7e-144 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
JHKNLHEE_00138 2.2e-34
JHKNLHEE_00139 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JHKNLHEE_00140 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
JHKNLHEE_00141 3.3e-121 yetF S membrane
JHKNLHEE_00142 6.6e-251 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
JHKNLHEE_00143 1.4e-161 lplC G Binding-protein-dependent transport system inner membrane component
JHKNLHEE_00144 1.5e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
JHKNLHEE_00145 2.4e-289 lplA G Bacterial extracellular solute-binding protein
JHKNLHEE_00146 0.0 yetA
JHKNLHEE_00147 6.5e-156 yesZ 3.2.1.23 G beta-galactosidase activity
JHKNLHEE_00148 8e-123 yesZ 3.2.1.23 G beta-galactosidase activity
JHKNLHEE_00149 1.5e-63 yesZ 3.2.1.23 G beta-galactosidase activity
JHKNLHEE_00150 1.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
JHKNLHEE_00151 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
JHKNLHEE_00152 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
JHKNLHEE_00153 8.8e-113 yesV S Protein of unknown function, DUF624
JHKNLHEE_00154 8.7e-127 yesU S Domain of unknown function (DUF1961)
JHKNLHEE_00155 1.4e-132 E GDSL-like Lipase/Acylhydrolase
JHKNLHEE_00156 0.0 yesS K Transcriptional regulator
JHKNLHEE_00157 1.9e-197 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
JHKNLHEE_00158 1.4e-119 yesQ P Binding-protein-dependent transport system inner membrane component
JHKNLHEE_00159 6.2e-171 yesP G Binding-protein-dependent transport system inner membrane component
JHKNLHEE_00160 5.2e-245 yesO G Bacterial extracellular solute-binding protein
JHKNLHEE_00161 4.6e-158 yesN K helix_turn_helix, arabinose operon control protein
JHKNLHEE_00162 0.0 yesM 2.7.13.3 T Histidine kinase
JHKNLHEE_00163 4.5e-101 yesL S Protein of unknown function, DUF624
JHKNLHEE_00165 2.8e-99 yesJ K Acetyltransferase (GNAT) family
JHKNLHEE_00166 5.2e-104 cotJC P Spore Coat
JHKNLHEE_00167 5.6e-45 cotJB S CotJB protein
JHKNLHEE_00168 1.5e-44 cotJA S Spore coat associated protein JA (CotJA)
JHKNLHEE_00169 2e-144 yesF GM NAD(P)H-binding
JHKNLHEE_00170 1.6e-79 yesE S SnoaL-like domain
JHKNLHEE_00171 6.7e-99 dhaR3 K Transcriptional regulator
JHKNLHEE_00173 2.7e-126 yeeN K transcriptional regulatory protein
JHKNLHEE_00175 7.4e-211 S Tetratricopeptide repeat
JHKNLHEE_00176 3.6e-58 3.4.24.40 CO amine dehydrogenase activity
JHKNLHEE_00177 5.9e-96 3.4.24.40 CO amine dehydrogenase activity
JHKNLHEE_00178 0.0 L nucleic acid phosphodiester bond hydrolysis
JHKNLHEE_00179 2.7e-82 S Protein of unknown function, DUF600
JHKNLHEE_00182 3.7e-101 S response regulator aspartate phosphatase
JHKNLHEE_00184 6.4e-249 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JHKNLHEE_00185 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
JHKNLHEE_00186 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JHKNLHEE_00187 1.3e-148 yerO K Transcriptional regulator
JHKNLHEE_00188 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JHKNLHEE_00189 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
JHKNLHEE_00190 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JHKNLHEE_00191 7.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JHKNLHEE_00192 1.6e-123 sapB S MgtC SapB transporter
JHKNLHEE_00193 1.9e-194 yerI S homoserine kinase type II (protein kinase fold)
JHKNLHEE_00195 5.4e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
JHKNLHEE_00196 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JHKNLHEE_00197 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
JHKNLHEE_00198 4.9e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
JHKNLHEE_00199 4.4e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
JHKNLHEE_00200 4.8e-51 yerC S protein conserved in bacteria
JHKNLHEE_00201 1.8e-189 yerB S Protein of unknown function (DUF3048) C-terminal domain
JHKNLHEE_00202 0.0 yerA 3.5.4.2 F adenine deaminase
JHKNLHEE_00203 2.7e-27 S Protein of unknown function (DUF2892)
JHKNLHEE_00204 4.3e-231 yjeH E Amino acid permease
JHKNLHEE_00205 1e-72 K helix_turn_helix ASNC type
JHKNLHEE_00206 6.1e-230 purD 6.3.4.13 F Belongs to the GARS family
JHKNLHEE_00207 2.7e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
JHKNLHEE_00208 3.7e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JHKNLHEE_00209 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
JHKNLHEE_00210 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JHKNLHEE_00211 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JHKNLHEE_00212 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JHKNLHEE_00213 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JHKNLHEE_00214 3.7e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
JHKNLHEE_00215 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JHKNLHEE_00216 8.5e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JHKNLHEE_00217 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JHKNLHEE_00218 8e-28 yebG S NETI protein
JHKNLHEE_00219 4e-93 yebE S UPF0316 protein
JHKNLHEE_00221 2.3e-118 yebC M Membrane
JHKNLHEE_00222 3.3e-210 pbuG S permease
JHKNLHEE_00224 8.3e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
JHKNLHEE_00225 0.0 yebA E COG1305 Transglutaminase-like enzymes
JHKNLHEE_00226 7.5e-222 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
JHKNLHEE_00227 4.3e-175 yeaC S COG0714 MoxR-like ATPases
JHKNLHEE_00228 3.5e-152 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JHKNLHEE_00229 1.3e-252 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
JHKNLHEE_00230 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
JHKNLHEE_00231 6.7e-176 yeaA S Protein of unknown function (DUF4003)
JHKNLHEE_00232 1.1e-138 ydjP I Alpha/beta hydrolase family
JHKNLHEE_00233 1.4e-34 ydjO S Cold-inducible protein YdjO
JHKNLHEE_00235 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JHKNLHEE_00236 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JHKNLHEE_00237 4.7e-41 fer C Ferredoxin
JHKNLHEE_00238 5.5e-200 ypbB 5.1.3.1 S protein conserved in bacteria
JHKNLHEE_00239 6e-285 recQ 3.6.4.12 L DNA helicase
JHKNLHEE_00240 6.9e-99 ypbD S metal-dependent membrane protease
JHKNLHEE_00241 5.5e-74 ypbE M Lysin motif
JHKNLHEE_00242 2.8e-81 ypbF S Protein of unknown function (DUF2663)
JHKNLHEE_00243 1.5e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
JHKNLHEE_00244 9.1e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
JHKNLHEE_00245 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
JHKNLHEE_00246 1.5e-175 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
JHKNLHEE_00247 1.5e-118 prsW S Involved in the degradation of specific anti-sigma factors
JHKNLHEE_00248 2.4e-151 sleB 3.5.1.28 M Spore cortex-lytic enzyme
JHKNLHEE_00249 9.3e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
JHKNLHEE_00250 1.2e-107 ypfA M Flagellar protein YcgR
JHKNLHEE_00251 1.8e-23 S Family of unknown function (DUF5359)
JHKNLHEE_00252 2.8e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
JHKNLHEE_00253 2.1e-205 rpsA 1.17.7.4 J Ribosomal protein S1
JHKNLHEE_00254 1.3e-182 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
JHKNLHEE_00255 1e-07 S YpzI-like protein
JHKNLHEE_00256 3.3e-101 yphA
JHKNLHEE_00257 2.5e-161 seaA S YIEGIA protein
JHKNLHEE_00258 6e-28 ypzH
JHKNLHEE_00259 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
JHKNLHEE_00260 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
JHKNLHEE_00261 2e-18 yphE S Protein of unknown function (DUF2768)
JHKNLHEE_00262 3.3e-135 yphF
JHKNLHEE_00263 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JHKNLHEE_00264 1.8e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
JHKNLHEE_00265 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
JHKNLHEE_00266 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
JHKNLHEE_00267 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
JHKNLHEE_00268 4.2e-132 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
JHKNLHEE_00269 7.6e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
JHKNLHEE_00270 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
JHKNLHEE_00271 1.1e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
JHKNLHEE_00272 1.2e-216 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JHKNLHEE_00273 5.8e-205 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JHKNLHEE_00274 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
JHKNLHEE_00275 5.6e-294 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JHKNLHEE_00276 6.7e-179 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JHKNLHEE_00277 9.5e-114 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
JHKNLHEE_00278 1.8e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
JHKNLHEE_00279 8.4e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
JHKNLHEE_00280 3e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
JHKNLHEE_00281 1.4e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JHKNLHEE_00282 2.6e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
JHKNLHEE_00283 7.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
JHKNLHEE_00284 1e-232 S COG0457 FOG TPR repeat
JHKNLHEE_00285 8.1e-99 ypiB S Belongs to the UPF0302 family
JHKNLHEE_00286 7.2e-77 ypiF S Protein of unknown function (DUF2487)
JHKNLHEE_00287 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
JHKNLHEE_00288 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
JHKNLHEE_00289 4.3e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
JHKNLHEE_00290 3.4e-98 ypjA S membrane
JHKNLHEE_00291 1e-142 ypjB S sporulation protein
JHKNLHEE_00292 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
JHKNLHEE_00293 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
JHKNLHEE_00294 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
JHKNLHEE_00295 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
JHKNLHEE_00296 1.7e-128 bshB1 S proteins, LmbE homologs
JHKNLHEE_00297 6.9e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
JHKNLHEE_00298 2e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
JHKNLHEE_00299 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
JHKNLHEE_00300 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
JHKNLHEE_00301 4.7e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JHKNLHEE_00302 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JHKNLHEE_00303 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
JHKNLHEE_00304 6.7e-23 ypmA S Protein of unknown function (DUF4264)
JHKNLHEE_00305 3.4e-80 ypmB S protein conserved in bacteria
JHKNLHEE_00306 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
JHKNLHEE_00307 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
JHKNLHEE_00308 5.7e-129 dnaD L DNA replication protein DnaD
JHKNLHEE_00309 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JHKNLHEE_00310 8e-93 ypoC
JHKNLHEE_00311 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
JHKNLHEE_00312 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
JHKNLHEE_00313 4.8e-176 yppC S Protein of unknown function (DUF2515)
JHKNLHEE_00316 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
JHKNLHEE_00318 2.1e-48 yppG S YppG-like protein
JHKNLHEE_00319 8.6e-72 hspX O Belongs to the small heat shock protein (HSP20) family
JHKNLHEE_00320 1.6e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
JHKNLHEE_00321 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
JHKNLHEE_00322 1.6e-235 yprB L RNase_H superfamily
JHKNLHEE_00323 5.3e-90 ypsA S Belongs to the UPF0398 family
JHKNLHEE_00324 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
JHKNLHEE_00325 9.2e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
JHKNLHEE_00327 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
JHKNLHEE_00328 3.5e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JHKNLHEE_00329 4.8e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
JHKNLHEE_00330 3.9e-187 ptxS K transcriptional
JHKNLHEE_00331 1.1e-186 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
JHKNLHEE_00332 3e-102 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
JHKNLHEE_00333 1.9e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
JHKNLHEE_00334 4.6e-293 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
JHKNLHEE_00335 1.1e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
JHKNLHEE_00336 1.5e-226 pbuX F xanthine
JHKNLHEE_00337 7.7e-205 bcsA Q Naringenin-chalcone synthase
JHKNLHEE_00338 5.1e-87 ypbQ S protein conserved in bacteria
JHKNLHEE_00339 0.0 ypbR S Dynamin family
JHKNLHEE_00340 2.9e-38 ypbS S Protein of unknown function (DUF2533)
JHKNLHEE_00341 2e-07
JHKNLHEE_00342 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
JHKNLHEE_00344 1.8e-66 rnhA 3.1.26.4 L Ribonuclease
JHKNLHEE_00345 8.2e-120 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JHKNLHEE_00346 1.7e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
JHKNLHEE_00347 3e-29 ypeQ S Zinc-finger
JHKNLHEE_00348 3.1e-107 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
JHKNLHEE_00349 2.2e-80 yokK S SMI1 / KNR4 family
JHKNLHEE_00350 1.9e-94 yokJ S SMI1 / KNR4 family (SUKH-1)
JHKNLHEE_00351 3.8e-291 UW nuclease activity
JHKNLHEE_00352 1.1e-101 yokH G SMI1 / KNR4 family
JHKNLHEE_00353 2.4e-275 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
JHKNLHEE_00354 1e-198 yobO M Pectate lyase superfamily protein
JHKNLHEE_00355 2.4e-221 yobO M Pectate lyase superfamily protein
JHKNLHEE_00356 9.3e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
JHKNLHEE_00357 3.8e-136 yobQ K helix_turn_helix, arabinose operon control protein
JHKNLHEE_00358 1.2e-140 yobR 2.3.1.1 J FR47-like protein
JHKNLHEE_00359 3.6e-97 yobS K Transcriptional regulator
JHKNLHEE_00360 7.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
JHKNLHEE_00361 8.3e-87 yobU K Bacterial transcription activator, effector binding domain
JHKNLHEE_00362 6.2e-171 yobV K WYL domain
JHKNLHEE_00363 6.3e-91 yobW
JHKNLHEE_00364 1e-51 czrA K transcriptional
JHKNLHEE_00365 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
JHKNLHEE_00366 1.5e-92 yozB S membrane
JHKNLHEE_00367 8.6e-142
JHKNLHEE_00368 2.6e-91 yocC
JHKNLHEE_00369 6e-185 yocD 3.4.17.13 V peptidase S66
JHKNLHEE_00370 1.2e-202 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
JHKNLHEE_00371 9.2e-198 desK 2.7.13.3 T Histidine kinase
JHKNLHEE_00372 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JHKNLHEE_00374 2.6e-107 yocH CBM50 M COG1388 FOG LysM repeat
JHKNLHEE_00375 0.0 recQ 3.6.4.12 L DNA helicase
JHKNLHEE_00376 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JHKNLHEE_00377 3.3e-83 dksA T general stress protein
JHKNLHEE_00378 5.4e-53 yocL
JHKNLHEE_00379 6.2e-32
JHKNLHEE_00380 3.7e-87 yocM O Belongs to the small heat shock protein (HSP20) family
JHKNLHEE_00381 1.1e-40 yozN
JHKNLHEE_00382 1.9e-36 yocN
JHKNLHEE_00383 4.2e-56 yozO S Bacterial PH domain
JHKNLHEE_00384 2.7e-31 yozC
JHKNLHEE_00385 5.2e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
JHKNLHEE_00386 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
JHKNLHEE_00387 6e-165 sodA 1.15.1.1 P Superoxide dismutase
JHKNLHEE_00388 4.5e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
JHKNLHEE_00389 1.1e-167 yocS S -transporter
JHKNLHEE_00390 9.1e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
JHKNLHEE_00391 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
JHKNLHEE_00392 0.0 yojO P Von Willebrand factor
JHKNLHEE_00393 3.2e-161 yojN S ATPase family associated with various cellular activities (AAA)
JHKNLHEE_00394 5.6e-109 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JHKNLHEE_00395 1.8e-197 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
JHKNLHEE_00396 5.9e-230 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
JHKNLHEE_00397 5.8e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JHKNLHEE_00399 2.2e-241 norM V Multidrug efflux pump
JHKNLHEE_00400 9.3e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
JHKNLHEE_00401 2.1e-125 yojG S deacetylase
JHKNLHEE_00402 2.2e-60 yojF S Protein of unknown function (DUF1806)
JHKNLHEE_00403 1.5e-43
JHKNLHEE_00404 4.3e-161 rarD S -transporter
JHKNLHEE_00405 5.5e-59 yozR S COG0071 Molecular chaperone (small heat shock protein)
JHKNLHEE_00406 2e-09
JHKNLHEE_00407 1e-198 gntP EG COG2610 H gluconate symporter and related permeases
JHKNLHEE_00408 1.4e-63 yodA S tautomerase
JHKNLHEE_00409 6.3e-54 yodB K transcriptional
JHKNLHEE_00410 1.4e-107 yodC C nitroreductase
JHKNLHEE_00411 2.7e-111 mhqD S Carboxylesterase
JHKNLHEE_00412 1.2e-137 yodE E COG0346 Lactoylglutathione lyase and related lyases
JHKNLHEE_00413 3.3e-28 yodE E COG0346 Lactoylglutathione lyase and related lyases
JHKNLHEE_00414 6.2e-28 S Protein of unknown function (DUF3311)
JHKNLHEE_00415 1.1e-265 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JHKNLHEE_00416 3.4e-250 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
JHKNLHEE_00417 2.4e-127 yodH Q Methyltransferase
JHKNLHEE_00418 2e-23 yodI
JHKNLHEE_00419 2.1e-138 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
JHKNLHEE_00420 1.2e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
JHKNLHEE_00421 5.3e-09
JHKNLHEE_00422 7.9e-54 yodL S YodL-like
JHKNLHEE_00423 6.6e-105 yodM 3.6.1.27 I Acid phosphatase homologues
JHKNLHEE_00424 2.8e-24 yozD S YozD-like protein
JHKNLHEE_00426 6e-123 yodN
JHKNLHEE_00427 3.1e-36 yozE S Belongs to the UPF0346 family
JHKNLHEE_00428 2.9e-47 yokU S YokU-like protein, putative antitoxin
JHKNLHEE_00429 3.9e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
JHKNLHEE_00430 8.8e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
JHKNLHEE_00431 1.2e-257 yodQ 3.5.1.16 E Acetylornithine deacetylase
JHKNLHEE_00432 5.2e-116 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
JHKNLHEE_00433 2.4e-09 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JHKNLHEE_00434 2.1e-238 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JHKNLHEE_00436 9.2e-144 yiiD K acetyltransferase
JHKNLHEE_00437 8e-254 cgeD M maturation of the outermost layer of the spore
JHKNLHEE_00438 5.9e-38 cgeC
JHKNLHEE_00439 4.8e-64 cgeA
JHKNLHEE_00440 1.4e-186 cgeB S Spore maturation protein
JHKNLHEE_00441 6.4e-210 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
JHKNLHEE_00442 5.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
JHKNLHEE_00443 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
JHKNLHEE_00444 3.5e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JHKNLHEE_00445 1.6e-70 ypoP K transcriptional
JHKNLHEE_00446 1.9e-221 mepA V MATE efflux family protein
JHKNLHEE_00447 1.2e-28 ypmT S Uncharacterized ympT
JHKNLHEE_00448 1.1e-98 ypmS S protein conserved in bacteria
JHKNLHEE_00449 3.7e-137 ypmR E GDSL-like Lipase/Acylhydrolase
JHKNLHEE_00450 3.5e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
JHKNLHEE_00451 3.1e-40 ypmP S Protein of unknown function (DUF2535)
JHKNLHEE_00452 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JHKNLHEE_00453 3.4e-183 pspF K Transcriptional regulator
JHKNLHEE_00454 4.2e-110 hlyIII S protein, Hemolysin III
JHKNLHEE_00455 1.4e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
JHKNLHEE_00456 1.4e-92 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JHKNLHEE_00457 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
JHKNLHEE_00458 4.3e-112 ypjP S YpjP-like protein
JHKNLHEE_00459 1.6e-143 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
JHKNLHEE_00460 1.7e-75 yphP S Belongs to the UPF0403 family
JHKNLHEE_00461 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
JHKNLHEE_00462 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
JHKNLHEE_00463 3.5e-106 ypgQ S phosphohydrolase
JHKNLHEE_00464 9.2e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
JHKNLHEE_00465 4.7e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JHKNLHEE_00466 2.3e-215 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
JHKNLHEE_00467 1e-30 cspD K Cold-shock protein
JHKNLHEE_00468 5.3e-164 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
JHKNLHEE_00469 7.3e-258 glpT G -transporter
JHKNLHEE_00470 4.7e-33 S Protein of unknown function (DUF2651)
JHKNLHEE_00471 3.7e-168 ybfA 3.4.15.5 K FR47-like protein
JHKNLHEE_00472 1.1e-220 ybfB G COG0477 Permeases of the major facilitator superfamily
JHKNLHEE_00474 0.0 ybfG M Domain of unknown function (DUF1906)
JHKNLHEE_00475 4.4e-161 ybfH EG EamA-like transporter family
JHKNLHEE_00476 3.3e-144 msmR K AraC-like ligand binding domain
JHKNLHEE_00477 9.9e-211 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
JHKNLHEE_00478 1.1e-175 mpr 3.4.21.19 M Belongs to the peptidase S1B family
JHKNLHEE_00480 7e-164 S Alpha/beta hydrolase family
JHKNLHEE_00481 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JHKNLHEE_00482 2.7e-85 ybfM S SNARE associated Golgi protein
JHKNLHEE_00483 2.4e-147 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
JHKNLHEE_00484 3e-44 ybfN
JHKNLHEE_00485 1.5e-191 yceA S Belongs to the UPF0176 family
JHKNLHEE_00486 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
JHKNLHEE_00487 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JHKNLHEE_00488 5.7e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
JHKNLHEE_00489 3.1e-128 K UTRA
JHKNLHEE_00491 2.7e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
JHKNLHEE_00492 1.1e-259 mmuP E amino acid
JHKNLHEE_00493 3e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
JHKNLHEE_00495 8.1e-255 agcS E Sodium alanine symporter
JHKNLHEE_00496 2.9e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
JHKNLHEE_00497 3.1e-121 phoQ 2.7.13.3 T Histidine kinase
JHKNLHEE_00498 3.9e-78 phoQ 2.7.13.3 T Histidine kinase
JHKNLHEE_00499 2.3e-168 glnL T Regulator
JHKNLHEE_00500 1e-173 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
JHKNLHEE_00501 4.9e-271 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
JHKNLHEE_00502 2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
JHKNLHEE_00503 9.4e-269 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
JHKNLHEE_00504 2.1e-123 ycbG K FCD
JHKNLHEE_00505 5.6e-183 garD 4.2.1.42, 4.2.1.7 G Altronate
JHKNLHEE_00506 2.9e-78 garD 4.2.1.42, 4.2.1.7 G Altronate
JHKNLHEE_00507 1.5e-172 ycbJ S Macrolide 2'-phosphotransferase
JHKNLHEE_00508 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
JHKNLHEE_00509 9.9e-169 eamA1 EG spore germination
JHKNLHEE_00510 6.5e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JHKNLHEE_00511 2.2e-168 T PhoQ Sensor
JHKNLHEE_00512 3.5e-166 ycbN V ABC transporter, ATP-binding protein
JHKNLHEE_00513 2.5e-113 S ABC-2 family transporter protein
JHKNLHEE_00514 2.9e-50 ycbP S Protein of unknown function (DUF2512)
JHKNLHEE_00515 3.4e-76 sleB 3.5.1.28 M Cell wall
JHKNLHEE_00516 9e-72 ycbR T vWA found in TerF C terminus
JHKNLHEE_00517 2.9e-44 ycbR T vWA found in TerF C terminus
JHKNLHEE_00518 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
JHKNLHEE_00519 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
JHKNLHEE_00520 4.9e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JHKNLHEE_00521 1.9e-118 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JHKNLHEE_00522 1.6e-202 ycbU E Selenocysteine lyase
JHKNLHEE_00523 1.8e-230 lmrB EGP the major facilitator superfamily
JHKNLHEE_00524 3.1e-101 yxaF K Transcriptional regulator
JHKNLHEE_00525 1.9e-198 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
JHKNLHEE_00526 1.6e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
JHKNLHEE_00527 4.6e-56 S RDD family
JHKNLHEE_00528 1.6e-199 yccF K DNA-templated transcriptional preinitiation complex assembly
JHKNLHEE_00529 6.6e-160 2.7.13.3 T GHKL domain
JHKNLHEE_00530 7.1e-36 lytR_2 T LytTr DNA-binding domain
JHKNLHEE_00531 9.7e-60 lytR_2 T LytTr DNA-binding domain
JHKNLHEE_00532 1.2e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
JHKNLHEE_00533 4.2e-201 natB CP ABC-2 family transporter protein
JHKNLHEE_00534 1e-173 yccK C Aldo keto reductase
JHKNLHEE_00535 1.1e-170 ycdA S Domain of unknown function (DUF5105)
JHKNLHEE_00536 1.1e-272 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
JHKNLHEE_00537 1.2e-256 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
JHKNLHEE_00538 7.3e-94 cwlK M D-alanyl-D-alanine carboxypeptidase
JHKNLHEE_00539 3.2e-104 S response regulator aspartate phosphatase
JHKNLHEE_00540 1.2e-35 S response regulator aspartate phosphatase
JHKNLHEE_00541 4e-139 IQ Enoyl-(Acyl carrier protein) reductase
JHKNLHEE_00542 2.1e-176 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
JHKNLHEE_00543 6.5e-153 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
JHKNLHEE_00544 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
JHKNLHEE_00545 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
JHKNLHEE_00546 6.4e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
JHKNLHEE_00547 9.8e-183 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JHKNLHEE_00548 1.6e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
JHKNLHEE_00549 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
JHKNLHEE_00550 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
JHKNLHEE_00551 1.4e-136 terC P Protein of unknown function (DUF475)
JHKNLHEE_00552 0.0 yceG S Putative component of 'biosynthetic module'
JHKNLHEE_00553 2e-192 yceH P Belongs to the TelA family
JHKNLHEE_00554 1.5e-217 naiP P Uncharacterised MFS-type transporter YbfB
JHKNLHEE_00555 5.8e-203 yceJ EGP Uncharacterised MFS-type transporter YbfB
JHKNLHEE_00556 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
JHKNLHEE_00557 2.5e-228 proV 3.6.3.32 E glycine betaine
JHKNLHEE_00558 1.3e-127 opuAB P glycine betaine
JHKNLHEE_00559 1.5e-163 opuAC E glycine betaine
JHKNLHEE_00560 1.5e-214 amhX S amidohydrolase
JHKNLHEE_00561 2.5e-256 ycgA S Membrane
JHKNLHEE_00562 4.5e-80 ycgB
JHKNLHEE_00563 2.6e-269 amyE 3.2.1.1 GH13 G alpha-amylase
JHKNLHEE_00564 2.7e-97 amyE 3.2.1.1 GH13 G alpha-amylase
JHKNLHEE_00565 3.6e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
JHKNLHEE_00566 3.3e-289 lctP C L-lactate permease
JHKNLHEE_00567 7.8e-148 yqcI S YqcI/YcgG family
JHKNLHEE_00568 1.2e-152 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
JHKNLHEE_00569 1.2e-93 ycgI S Domain of unknown function (DUF1989)
JHKNLHEE_00570 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
JHKNLHEE_00571 7.5e-106 tmrB S AAA domain
JHKNLHEE_00572 6.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JHKNLHEE_00573 1.2e-73 yneK S Protein of unknown function (DUF2621)
JHKNLHEE_00574 4.1e-65 hspX O Spore coat protein
JHKNLHEE_00575 3.9e-19 sspP S Belongs to the SspP family
JHKNLHEE_00576 2.2e-14 sspO S Belongs to the SspO family
JHKNLHEE_00577 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JHKNLHEE_00578 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JHKNLHEE_00580 3.1e-08 sspN S Small acid-soluble spore protein N family
JHKNLHEE_00581 3.9e-35 tlp S Belongs to the Tlp family
JHKNLHEE_00582 1.2e-73 yneP S Thioesterase-like superfamily
JHKNLHEE_00583 2.2e-53 yneQ
JHKNLHEE_00584 4.1e-49 yneR S Belongs to the HesB IscA family
JHKNLHEE_00585 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
JHKNLHEE_00586 6.6e-69 yccU S CoA-binding protein
JHKNLHEE_00587 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JHKNLHEE_00588 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JHKNLHEE_00589 2.3e-12
JHKNLHEE_00590 8.6e-57 ynfC
JHKNLHEE_00591 5.9e-250 agcS E Sodium alanine symporter
JHKNLHEE_00592 4.2e-294 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
JHKNLHEE_00594 2.4e-155 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
JHKNLHEE_00595 3.5e-76 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
JHKNLHEE_00596 6.2e-293 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
JHKNLHEE_00597 1.4e-75 yngA S membrane
JHKNLHEE_00598 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
JHKNLHEE_00599 5.5e-104 yngC S membrane-associated protein
JHKNLHEE_00600 1.2e-232 nrnB S phosphohydrolase (DHH superfamily)
JHKNLHEE_00601 2e-288 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
JHKNLHEE_00602 1.7e-134 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
JHKNLHEE_00603 4.4e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
JHKNLHEE_00604 6.6e-31 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
JHKNLHEE_00605 3.3e-250 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
JHKNLHEE_00606 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
JHKNLHEE_00607 2.7e-208 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
JHKNLHEE_00608 8.5e-303 yngK T Glycosyl hydrolase-like 10
JHKNLHEE_00609 9.9e-62 yngL S Protein of unknown function (DUF1360)
JHKNLHEE_00610 6.1e-38 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
JHKNLHEE_00611 2.5e-153 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
JHKNLHEE_00612 1e-154 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
JHKNLHEE_00613 6.6e-213 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
JHKNLHEE_00614 5.6e-31 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
JHKNLHEE_00615 1.7e-290 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JHKNLHEE_00616 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JHKNLHEE_00617 6.8e-273 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
JHKNLHEE_00618 7.1e-186 yoxA 5.1.3.3 G Aldose 1-epimerase
JHKNLHEE_00619 2.3e-246 yoeA V MATE efflux family protein
JHKNLHEE_00620 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
JHKNLHEE_00622 2.2e-96 L Integrase
JHKNLHEE_00623 8.7e-34 yoeD G Helix-turn-helix domain
JHKNLHEE_00624 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
JHKNLHEE_00625 8.8e-156 gltR1 K Transcriptional regulator
JHKNLHEE_00626 1.2e-185 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
JHKNLHEE_00627 2.3e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
JHKNLHEE_00628 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
JHKNLHEE_00629 7.8e-155 gltC K Transcriptional regulator
JHKNLHEE_00630 1.3e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JHKNLHEE_00631 1.6e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JHKNLHEE_00632 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
JHKNLHEE_00633 2.4e-122 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
JHKNLHEE_00634 7.1e-39 yoxC S Bacterial protein of unknown function (DUF948)
JHKNLHEE_00635 7.9e-124 yoxB
JHKNLHEE_00636 3.9e-93 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
JHKNLHEE_00637 4e-234 yoaB EGP Major facilitator Superfamily
JHKNLHEE_00638 2.2e-279 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
JHKNLHEE_00639 5.8e-183 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JHKNLHEE_00640 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JHKNLHEE_00641 1.1e-33 yoaF
JHKNLHEE_00642 6.5e-08 ywlA S Uncharacterised protein family (UPF0715)
JHKNLHEE_00643 2.6e-13
JHKNLHEE_00644 7.7e-35 S Protein of unknown function (DUF4025)
JHKNLHEE_00645 7.4e-183 mcpU NT methyl-accepting chemotaxis protein
JHKNLHEE_00646 2.4e-278 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
JHKNLHEE_00647 5.5e-132 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
JHKNLHEE_00648 2.3e-111 yoaK S Membrane
JHKNLHEE_00649 2.1e-196 pelB 4.2.2.10, 4.2.2.2 G Amb_all
JHKNLHEE_00650 3.9e-130 yoqW S Belongs to the SOS response-associated peptidase family
JHKNLHEE_00653 5e-164 oxdC 4.1.1.2 G Oxalate decarboxylase
JHKNLHEE_00654 1.7e-51 oxdC 4.1.1.2 G Oxalate decarboxylase
JHKNLHEE_00657 4.4e-83
JHKNLHEE_00658 4.3e-169 yoaR V vancomycin resistance protein
JHKNLHEE_00659 7.3e-75 yoaS S Protein of unknown function (DUF2975)
JHKNLHEE_00660 4.4e-30 yozG K Transcriptional regulator
JHKNLHEE_00661 2.4e-147 yoaT S Protein of unknown function (DUF817)
JHKNLHEE_00662 8.2e-158 yoaU K LysR substrate binding domain
JHKNLHEE_00663 5.3e-156 yijE EG EamA-like transporter family
JHKNLHEE_00664 1.6e-76 yoaW
JHKNLHEE_00665 1.5e-228 yitG EGP Major facilitator Superfamily
JHKNLHEE_00666 2.8e-154 yitH K Acetyltransferase (GNAT) domain
JHKNLHEE_00667 1.3e-70 yjcF S Acetyltransferase (GNAT) domain
JHKNLHEE_00668 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
JHKNLHEE_00669 3.3e-54 yajQ S Belongs to the UPF0234 family
JHKNLHEE_00670 4.5e-160 cvfB S protein conserved in bacteria
JHKNLHEE_00671 8.5e-94
JHKNLHEE_00672 5.4e-167
JHKNLHEE_00673 1.5e-97 S Sporulation delaying protein SdpA
JHKNLHEE_00674 1.5e-58 K Transcriptional regulator PadR-like family
JHKNLHEE_00675 1.6e-92
JHKNLHEE_00676 1.4e-44 yitR S Domain of unknown function (DUF3784)
JHKNLHEE_00677 4.2e-308 nprB 3.4.24.28 E Peptidase M4
JHKNLHEE_00678 3.5e-157 yitS S protein conserved in bacteria
JHKNLHEE_00679 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
JHKNLHEE_00680 5e-73 ipi S Intracellular proteinase inhibitor
JHKNLHEE_00681 1.2e-17 S Protein of unknown function (DUF3813)
JHKNLHEE_00683 6e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
JHKNLHEE_00684 2.9e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
JHKNLHEE_00685 6.2e-51 yitW S metal-sulfur cluster biosynthetic enzyme
JHKNLHEE_00686 1.5e-22 pilT S Proteolipid membrane potential modulator
JHKNLHEE_00687 8.3e-268 yitY C D-arabinono-1,4-lactone oxidase
JHKNLHEE_00688 1.7e-88 norB G Major Facilitator Superfamily
JHKNLHEE_00689 3.6e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JHKNLHEE_00690 6.5e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JHKNLHEE_00691 1.6e-135 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
JHKNLHEE_00692 5.4e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
JHKNLHEE_00693 1.3e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
JHKNLHEE_00694 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
JHKNLHEE_00695 1.5e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JHKNLHEE_00696 9.5e-28 yjzC S YjzC-like protein
JHKNLHEE_00697 2.3e-16 yjzD S Protein of unknown function (DUF2929)
JHKNLHEE_00698 1.8e-141 yjaU I carboxylic ester hydrolase activity
JHKNLHEE_00699 6.4e-99 yjaV
JHKNLHEE_00700 1.6e-182 med S Transcriptional activator protein med
JHKNLHEE_00701 7.3e-26 comZ S ComZ
JHKNLHEE_00702 2.7e-22 yjzB
JHKNLHEE_00703 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JHKNLHEE_00704 8.9e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
JHKNLHEE_00705 2.5e-149 yjaZ O Zn-dependent protease
JHKNLHEE_00706 1.8e-184 appD P Belongs to the ABC transporter superfamily
JHKNLHEE_00707 3.6e-185 appF E Belongs to the ABC transporter superfamily
JHKNLHEE_00708 1.4e-279 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
JHKNLHEE_00709 1.9e-167 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JHKNLHEE_00710 1.8e-154 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JHKNLHEE_00711 2.8e-145 yjbA S Belongs to the UPF0736 family
JHKNLHEE_00712 3e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
JHKNLHEE_00713 0.0 oppA E ABC transporter substrate-binding protein
JHKNLHEE_00714 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JHKNLHEE_00715 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JHKNLHEE_00716 3.4e-197 oppD P Belongs to the ABC transporter superfamily
JHKNLHEE_00717 5.5e-172 oppF E Belongs to the ABC transporter superfamily
JHKNLHEE_00718 2.7e-203 yjbB EGP Major Facilitator Superfamily
JHKNLHEE_00719 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JHKNLHEE_00720 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
JHKNLHEE_00721 6e-112 yjbE P Integral membrane protein TerC family
JHKNLHEE_00722 4.4e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
JHKNLHEE_00723 4e-220 yjbF S Competence protein
JHKNLHEE_00724 0.0 pepF E oligoendopeptidase F
JHKNLHEE_00725 1.8e-20
JHKNLHEE_00727 1.2e-168 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
JHKNLHEE_00728 3.7e-72 yjbI S Bacterial-like globin
JHKNLHEE_00729 3.2e-98 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
JHKNLHEE_00730 4.1e-101 yjbK S protein conserved in bacteria
JHKNLHEE_00731 7.1e-62 yjbL S Belongs to the UPF0738 family
JHKNLHEE_00732 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
JHKNLHEE_00733 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JHKNLHEE_00734 5.2e-159 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JHKNLHEE_00735 1.5e-127 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
JHKNLHEE_00736 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
JHKNLHEE_00737 1.1e-135 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JHKNLHEE_00738 3.9e-105 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
JHKNLHEE_00739 4.4e-216 thiO 1.4.3.19 E Glycine oxidase
JHKNLHEE_00740 8.8e-30 thiS H thiamine diphosphate biosynthetic process
JHKNLHEE_00741 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
JHKNLHEE_00742 6.7e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
JHKNLHEE_00743 1.3e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
JHKNLHEE_00744 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
JHKNLHEE_00745 1.4e-52 yjbX S Spore coat protein
JHKNLHEE_00746 5.2e-83 cotZ S Spore coat protein
JHKNLHEE_00747 3.4e-96 cotY S Spore coat protein Z
JHKNLHEE_00748 6.4e-77 cotX S Spore Coat Protein X and V domain
JHKNLHEE_00749 3e-32 cotW
JHKNLHEE_00750 2.3e-55 cotV S Spore Coat Protein X and V domain
JHKNLHEE_00751 4.3e-56 yjcA S Protein of unknown function (DUF1360)
JHKNLHEE_00754 2.9e-38 spoVIF S Stage VI sporulation protein F
JHKNLHEE_00755 0.0 yjcD 3.6.4.12 L DNA helicase
JHKNLHEE_00756 1.7e-38
JHKNLHEE_00757 3.9e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JHKNLHEE_00758 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
JHKNLHEE_00759 1.8e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
JHKNLHEE_00760 8.6e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
JHKNLHEE_00761 6.5e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
JHKNLHEE_00762 1.7e-96 rimJ 2.3.1.128 J Alanine acetyltransferase
JHKNLHEE_00763 1.3e-210 yjcL S Protein of unknown function (DUF819)
JHKNLHEE_00766 1.3e-37
JHKNLHEE_00767 1e-29
JHKNLHEE_00768 5e-238 M nucleic acid phosphodiester bond hydrolysis
JHKNLHEE_00769 9.6e-11
JHKNLHEE_00770 3.4e-33 K Helix-turn-helix XRE-family like proteins
JHKNLHEE_00771 3.3e-40
JHKNLHEE_00773 3.6e-185 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
JHKNLHEE_00774 8.7e-30 cspL K Cold shock
JHKNLHEE_00775 6.1e-79 carD K Transcription factor
JHKNLHEE_00776 6.1e-144 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
JHKNLHEE_00777 1.1e-68 rhaS5 K AraC-like ligand binding domain
JHKNLHEE_00778 6.4e-85 rhaS5 K AraC-like ligand binding domain
JHKNLHEE_00779 7.8e-169 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
JHKNLHEE_00780 2.1e-117 ydeE K AraC family transcriptional regulator
JHKNLHEE_00781 6.6e-262 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JHKNLHEE_00782 5.1e-216 ydeG EGP Major facilitator superfamily
JHKNLHEE_00783 1.4e-44 ydeH
JHKNLHEE_00784 6.4e-105 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
JHKNLHEE_00785 7.8e-112
JHKNLHEE_00786 1.1e-31 S SNARE associated Golgi protein
JHKNLHEE_00787 8.3e-15 ptsH G PTS HPr component phosphorylation site
JHKNLHEE_00788 3.4e-84 K Transcriptional regulator C-terminal region
JHKNLHEE_00789 1.1e-50 ydeK EG -transporter
JHKNLHEE_00790 3.2e-71 ydeK EG -transporter
JHKNLHEE_00791 8.1e-87 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JHKNLHEE_00792 7.4e-166 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JHKNLHEE_00793 1.2e-73 maoC I N-terminal half of MaoC dehydratase
JHKNLHEE_00794 2.8e-105 ydeN S Serine hydrolase
JHKNLHEE_00795 3e-56 K HxlR-like helix-turn-helix
JHKNLHEE_00796 5.4e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
JHKNLHEE_00797 2e-68 ydeP K Transcriptional regulator
JHKNLHEE_00798 3.7e-32 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
JHKNLHEE_00799 1.6e-48 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
JHKNLHEE_00800 8.1e-192 ydeR EGP Major facilitator Superfamily
JHKNLHEE_00801 4.6e-103 ydeS K Transcriptional regulator
JHKNLHEE_00802 8.2e-57 arsR K transcriptional
JHKNLHEE_00803 7e-229 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JHKNLHEE_00804 1.7e-72 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
JHKNLHEE_00805 2.1e-148 ydfB J GNAT acetyltransferase
JHKNLHEE_00806 2.2e-157 ydfC EG EamA-like transporter family
JHKNLHEE_00807 7.9e-274 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JHKNLHEE_00808 5e-116 ydfE S Flavin reductase like domain
JHKNLHEE_00809 7.8e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
JHKNLHEE_00810 1e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JHKNLHEE_00812 2.7e-176 ydfH 2.7.13.3 T Histidine kinase
JHKNLHEE_00813 3.5e-109 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JHKNLHEE_00814 0.0 ydfJ S drug exporters of the RND superfamily
JHKNLHEE_00815 1.4e-175 S Alpha/beta hydrolase family
JHKNLHEE_00816 8.5e-117 S Protein of unknown function (DUF554)
JHKNLHEE_00817 1.9e-144 K Bacterial transcription activator, effector binding domain
JHKNLHEE_00818 1.5e-153 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JHKNLHEE_00819 4e-110 ydfN C nitroreductase
JHKNLHEE_00820 3.4e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
JHKNLHEE_00821 8.8e-63 mhqP S DoxX
JHKNLHEE_00822 1e-54 traF CO Thioredoxin
JHKNLHEE_00823 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
JHKNLHEE_00824 6.3e-29
JHKNLHEE_00826 1.3e-25 ydfR S Protein of unknown function (DUF421)
JHKNLHEE_00827 5.1e-28 ydfR S Protein of unknown function (DUF421)
JHKNLHEE_00828 1.5e-121 ydfS S Protein of unknown function (DUF421)
JHKNLHEE_00829 1.9e-74 cotP O Belongs to the small heat shock protein (HSP20) family
JHKNLHEE_00830 2.3e-37 ydgA S Spore germination protein gerPA/gerPF
JHKNLHEE_00831 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
JHKNLHEE_00832 1.7e-97 K Bacterial regulatory proteins, tetR family
JHKNLHEE_00833 3.4e-50 S DoxX-like family
JHKNLHEE_00834 1.7e-84 yycN 2.3.1.128 K Acetyltransferase
JHKNLHEE_00835 4.6e-302 expZ S ABC transporter
JHKNLHEE_00836 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
JHKNLHEE_00837 8.7e-90 dinB S DinB family
JHKNLHEE_00838 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
JHKNLHEE_00839 0.0 ydgH S drug exporters of the RND superfamily
JHKNLHEE_00840 1e-113 drgA C nitroreductase
JHKNLHEE_00841 7.1e-69 ydgJ K Winged helix DNA-binding domain
JHKNLHEE_00842 2.2e-208 tcaB EGP Major facilitator Superfamily
JHKNLHEE_00843 1.2e-121 ydhB S membrane transporter protein
JHKNLHEE_00844 6.5e-122 ydhC K FCD
JHKNLHEE_00845 3.3e-244 ydhD M Glycosyl hydrolase
JHKNLHEE_00846 4.4e-211 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
JHKNLHEE_00847 1.3e-125
JHKNLHEE_00848 2e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
JHKNLHEE_00849 4.3e-67 frataxin S Domain of unknown function (DU1801)
JHKNLHEE_00851 2.9e-84 K Acetyltransferase (GNAT) domain
JHKNLHEE_00852 6.2e-182 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
JHKNLHEE_00853 1.2e-97 ydhK M Protein of unknown function (DUF1541)
JHKNLHEE_00854 4.6e-200 pbuE EGP Major facilitator Superfamily
JHKNLHEE_00855 1.2e-46 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
JHKNLHEE_00856 5.6e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
JHKNLHEE_00857 2.6e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JHKNLHEE_00858 8.1e-284 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JHKNLHEE_00859 4.3e-132 ydhQ K UTRA
JHKNLHEE_00860 4.4e-166 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
JHKNLHEE_00861 2.5e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
JHKNLHEE_00862 3.8e-212 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
JHKNLHEE_00863 6.1e-157 ydhU P Catalase
JHKNLHEE_00866 2.7e-171 ytaP S Acetyl xylan esterase (AXE1)
JHKNLHEE_00867 2.3e-187 msmR K Transcriptional regulator
JHKNLHEE_00868 1.5e-244 msmE G Bacterial extracellular solute-binding protein
JHKNLHEE_00869 2.4e-167 amyD P ABC transporter
JHKNLHEE_00870 2.2e-143 amyC P ABC transporter (permease)
JHKNLHEE_00871 5.3e-253 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
JHKNLHEE_00872 2.1e-51 ytwF P Sulfurtransferase
JHKNLHEE_00873 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
JHKNLHEE_00874 8.5e-54 ytvB S Protein of unknown function (DUF4257)
JHKNLHEE_00875 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
JHKNLHEE_00876 1.3e-210 yttB EGP Major facilitator Superfamily
JHKNLHEE_00877 1.9e-42 yttA 2.7.13.3 S Pfam Transposase IS66
JHKNLHEE_00878 0.0 bceB V ABC transporter (permease)
JHKNLHEE_00879 1.1e-138 bceA V ABC transporter, ATP-binding protein
JHKNLHEE_00880 4e-184 T PhoQ Sensor
JHKNLHEE_00881 3.3e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JHKNLHEE_00882 1.8e-232 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
JHKNLHEE_00883 9.1e-127 ytrE V ABC transporter, ATP-binding protein
JHKNLHEE_00884 1.9e-146
JHKNLHEE_00885 4.7e-153 P ABC-2 family transporter protein
JHKNLHEE_00886 4.2e-161 ytrB P abc transporter atp-binding protein
JHKNLHEE_00887 5.1e-66 ytrA K GntR family transcriptional regulator
JHKNLHEE_00889 1.5e-40 ytzC S Protein of unknown function (DUF2524)
JHKNLHEE_00890 1.8e-189 yhcC S Fe-S oxidoreductase
JHKNLHEE_00891 3.3e-106 ytqB J Putative rRNA methylase
JHKNLHEE_00892 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
JHKNLHEE_00893 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
JHKNLHEE_00894 2.7e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JHKNLHEE_00895 1.7e-254 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
JHKNLHEE_00896 0.0 asnB 6.3.5.4 E Asparagine synthase
JHKNLHEE_00897 4.7e-224 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JHKNLHEE_00898 9.7e-310 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JHKNLHEE_00899 1.6e-38 ytmB S Protein of unknown function (DUF2584)
JHKNLHEE_00900 1.1e-146 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
JHKNLHEE_00901 9.5e-189 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
JHKNLHEE_00902 1.4e-144 ytlC P ABC transporter
JHKNLHEE_00903 1.5e-141 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
JHKNLHEE_00904 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
JHKNLHEE_00905 1.1e-60 ytkC S Bacteriophage holin family
JHKNLHEE_00906 1e-75 dps P Belongs to the Dps family
JHKNLHEE_00908 1.1e-72 ytkA S YtkA-like
JHKNLHEE_00909 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
JHKNLHEE_00910 9.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
JHKNLHEE_00911 3.6e-41 rpmE2 J Ribosomal protein L31
JHKNLHEE_00912 2.3e-248 cydA 1.10.3.14 C oxidase, subunit
JHKNLHEE_00913 4e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
JHKNLHEE_00914 4.3e-24 S Domain of Unknown Function (DUF1540)
JHKNLHEE_00915 2.6e-150 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
JHKNLHEE_00916 1.8e-229 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
JHKNLHEE_00917 4.5e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
JHKNLHEE_00918 1.1e-169 troA P Belongs to the bacterial solute-binding protein 9 family
JHKNLHEE_00919 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
JHKNLHEE_00920 2.8e-271 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
JHKNLHEE_00921 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JHKNLHEE_00922 1.7e-151 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
JHKNLHEE_00923 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JHKNLHEE_00924 2.7e-271 menF 5.4.4.2 HQ Isochorismate synthase
JHKNLHEE_00925 7.4e-132 dksA T COG1734 DnaK suppressor protein
JHKNLHEE_00926 5.6e-152 galU 2.7.7.9 M Nucleotidyl transferase
JHKNLHEE_00927 1.7e-243 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JHKNLHEE_00928 2.9e-176 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
JHKNLHEE_00929 1.8e-226 ytcC M Glycosyltransferase Family 4
JHKNLHEE_00931 2.8e-204 cotS S Seems to be required for the assembly of the CotSA protein in spores
JHKNLHEE_00932 7.2e-214 cotSA M Glycosyl transferases group 1
JHKNLHEE_00933 1.1e-203 cotI S Spore coat protein
JHKNLHEE_00934 9.9e-77 tspO T membrane
JHKNLHEE_00935 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
JHKNLHEE_00936 5.4e-283 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
JHKNLHEE_00937 1.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
JHKNLHEE_00938 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JHKNLHEE_00939 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JHKNLHEE_00946 7.2e-152 ydjN U Involved in the tonB-independent uptake of proteins
JHKNLHEE_00947 4.5e-64 ydjM M Lytic transglycolase
JHKNLHEE_00948 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
JHKNLHEE_00949 2.7e-258 iolT EGP Major facilitator Superfamily
JHKNLHEE_00950 4e-195 S Ion transport 2 domain protein
JHKNLHEE_00951 4.1e-149 ydjI S virion core protein (lumpy skin disease virus)
JHKNLHEE_00952 2.5e-130 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
JHKNLHEE_00953 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JHKNLHEE_00954 1.9e-113 pspA KT Phage shock protein A
JHKNLHEE_00955 1.7e-171 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
JHKNLHEE_00956 2.7e-255 gutA G MFS/sugar transport protein
JHKNLHEE_00957 4.2e-200 gutB 1.1.1.14 E Dehydrogenase
JHKNLHEE_00958 0.0 K NB-ARC domain
JHKNLHEE_00959 3.2e-149 ydjC S Abhydrolase domain containing 18
JHKNLHEE_00961 7e-232 3.1.21.5, 3.6.4.12 L DEAD-like helicases superfamily
JHKNLHEE_00963 1.8e-13
JHKNLHEE_00964 4.9e-07 S Antitoxin to bacterial toxin RNase LS or RnlA
JHKNLHEE_00965 3.4e-67 rnhA 3.1.26.4 L Caulimovirus viroplasmin
JHKNLHEE_00966 6.1e-27 K Helix-turn-helix domain
JHKNLHEE_00968 9e-41 S protein domain associated with
JHKNLHEE_00969 2.2e-103 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
JHKNLHEE_00970 2.7e-31 xhlB S SPP1 phage holin
JHKNLHEE_00971 9.5e-27 xhlA S Haemolysin XhlA
JHKNLHEE_00976 5.2e-204 sidC L Phage minor structural protein
JHKNLHEE_00977 9.9e-50
JHKNLHEE_00978 3.4e-177
JHKNLHEE_00979 2.4e-28 S Phage tail assembly chaperone protein, TAC
JHKNLHEE_00980 2.2e-07 chiB 3.2.1.14 GH18 G Belongs to the glycosyl hydrolase 18 family
JHKNLHEE_00981 1.3e-34 S Phage tail tube protein
JHKNLHEE_00982 1.3e-29 S Protein of unknown function (DUF3168)
JHKNLHEE_00983 5.2e-37 S Bacteriophage HK97-gp10, putative tail-component
JHKNLHEE_00984 1.2e-26 S Phage head-tail joining protein
JHKNLHEE_00985 1.1e-28 S Phage gp6-like head-tail connector protein
JHKNLHEE_00987 1e-54 gpG
JHKNLHEE_00988 5.4e-44 S Phage minor structural protein GP20
JHKNLHEE_00990 4.5e-81 S Phage Mu protein F like protein
JHKNLHEE_00991 1.2e-120 S Phage portal protein, SPP1 Gp6-like
JHKNLHEE_00993 2.6e-196 S Phage terminase large subunit
JHKNLHEE_00994 1.4e-45 L Terminase small subunit
JHKNLHEE_00997 2.7e-79 L Transposase
JHKNLHEE_01007 1.2e-25
JHKNLHEE_01009 1.6e-18 yqaO S Phage-like element PBSX protein XtrA
JHKNLHEE_01011 4e-54 S Protein of unknown function (DUF1064)
JHKNLHEE_01012 1.4e-10 S YopX protein
JHKNLHEE_01014 2e-80 xkdC L IstB-like ATP binding protein
JHKNLHEE_01015 1.4e-45 L DnaD domain protein
JHKNLHEE_01016 4.9e-135 recT L RecT family
JHKNLHEE_01017 1.6e-153 yqaJ L YqaJ-like viral recombinase domain
JHKNLHEE_01023 3.5e-68
JHKNLHEE_01024 5e-68 S DNA binding
JHKNLHEE_01025 5.3e-34
JHKNLHEE_01026 1.6e-19 K Helix-turn-helix XRE-family like proteins
JHKNLHEE_01027 4.2e-46 xre K Helix-turn-helix XRE-family like proteins
JHKNLHEE_01028 8.9e-22 S Short C-terminal domain
JHKNLHEE_01029 4.2e-49 xkdA E IrrE N-terminal-like domain
JHKNLHEE_01030 9.8e-145 L Belongs to the 'phage' integrase family
JHKNLHEE_01031 8.3e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
JHKNLHEE_01032 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JHKNLHEE_01033 7.9e-129 ydiL S CAAX protease self-immunity
JHKNLHEE_01034 2.9e-27 ydiK S Domain of unknown function (DUF4305)
JHKNLHEE_01035 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JHKNLHEE_01036 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
JHKNLHEE_01037 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JHKNLHEE_01038 1.6e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
JHKNLHEE_01039 0.0 ydiF S ABC transporter
JHKNLHEE_01040 5.2e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JHKNLHEE_01041 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
JHKNLHEE_01042 4.9e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
JHKNLHEE_01043 2.6e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
JHKNLHEE_01044 1.8e-181 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JHKNLHEE_01045 7.9e-88 ytlQ
JHKNLHEE_01046 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
JHKNLHEE_01047 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
JHKNLHEE_01048 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
JHKNLHEE_01049 2e-45 ytzH S YtzH-like protein
JHKNLHEE_01050 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
JHKNLHEE_01051 2.7e-149 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
JHKNLHEE_01052 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
JHKNLHEE_01053 1.1e-50 ytzB S small secreted protein
JHKNLHEE_01054 4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
JHKNLHEE_01055 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
JHKNLHEE_01056 7.9e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
JHKNLHEE_01057 4.8e-148 ytpQ S Belongs to the UPF0354 family
JHKNLHEE_01058 2.8e-108 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JHKNLHEE_01059 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
JHKNLHEE_01060 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
JHKNLHEE_01061 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JHKNLHEE_01062 6.6e-17 ytxH S COG4980 Gas vesicle protein
JHKNLHEE_01063 2.8e-54 ytxJ O Protein of unknown function (DUF2847)
JHKNLHEE_01064 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
JHKNLHEE_01065 3.8e-182 ccpA K catabolite control protein A
JHKNLHEE_01066 2.1e-146 motA N flagellar motor
JHKNLHEE_01067 8.9e-125 motS N Flagellar motor protein
JHKNLHEE_01068 3.5e-224 acuC BQ histone deacetylase
JHKNLHEE_01069 3.5e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
JHKNLHEE_01070 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
JHKNLHEE_01071 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
JHKNLHEE_01072 1.8e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JHKNLHEE_01074 3.3e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JHKNLHEE_01075 8.5e-307 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
JHKNLHEE_01076 2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
JHKNLHEE_01077 1e-108 yttP K Transcriptional regulator
JHKNLHEE_01078 1e-153 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
JHKNLHEE_01079 4.6e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JHKNLHEE_01080 1.4e-237 brnQ E Component of the transport system for branched-chain amino acids
JHKNLHEE_01081 1e-207 iscS2 2.8.1.7 E Cysteine desulfurase
JHKNLHEE_01082 1e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JHKNLHEE_01083 1e-28 sspB S spore protein
JHKNLHEE_01084 1e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
JHKNLHEE_01085 0.0 ytcJ S amidohydrolase
JHKNLHEE_01086 6.3e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JHKNLHEE_01087 1.5e-178 sppA OU signal peptide peptidase SppA
JHKNLHEE_01088 1.5e-86 yteJ S RDD family
JHKNLHEE_01089 9.6e-108 ytfI S Protein of unknown function (DUF2953)
JHKNLHEE_01090 1.5e-66 ytfJ S Sporulation protein YtfJ
JHKNLHEE_01091 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JHKNLHEE_01092 2.8e-161 ytxK 2.1.1.72 L DNA methylase
JHKNLHEE_01093 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JHKNLHEE_01094 3e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
JHKNLHEE_01095 5.1e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
JHKNLHEE_01096 8.9e-267 argH 4.3.2.1 E argininosuccinate lyase
JHKNLHEE_01098 4.2e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JHKNLHEE_01099 1.7e-130 ytkL S Belongs to the UPF0173 family
JHKNLHEE_01100 2.9e-173 ytlI K LysR substrate binding domain
JHKNLHEE_01101 4.3e-100 ytmI K Acetyltransferase (GNAT) domain
JHKNLHEE_01102 2.1e-151 tcyK ET Bacterial periplasmic substrate-binding proteins
JHKNLHEE_01103 1.4e-144 tcyK M Bacterial periplasmic substrate-binding proteins
JHKNLHEE_01104 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
JHKNLHEE_01105 6.4e-120 tcyM U Binding-protein-dependent transport system inner membrane component
JHKNLHEE_01106 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
JHKNLHEE_01107 2.9e-182 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JHKNLHEE_01108 7.9e-45 ytnI O COG0695 Glutaredoxin and related proteins
JHKNLHEE_01109 1.8e-253 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JHKNLHEE_01110 6.6e-119 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
JHKNLHEE_01111 6.7e-237 ytnL 3.5.1.47 E hydrolase activity
JHKNLHEE_01112 3.4e-158 ytnM S membrane transporter protein
JHKNLHEE_01113 8e-241 ytoI K transcriptional regulator containing CBS domains
JHKNLHEE_01114 2.4e-47 ytpI S YtpI-like protein
JHKNLHEE_01115 2.3e-181 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
JHKNLHEE_01116 9.2e-29
JHKNLHEE_01117 8.2e-69 ytrI
JHKNLHEE_01118 3.2e-56 ytrH S Sporulation protein YtrH
JHKNLHEE_01119 0.0 dnaE 2.7.7.7 L DNA polymerase
JHKNLHEE_01120 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
JHKNLHEE_01121 2.7e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JHKNLHEE_01122 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
JHKNLHEE_01123 7.5e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
JHKNLHEE_01124 4.9e-311 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
JHKNLHEE_01125 3.3e-62 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
JHKNLHEE_01126 2.6e-192 ytvI S sporulation integral membrane protein YtvI
JHKNLHEE_01127 4.7e-71 yeaL S membrane
JHKNLHEE_01128 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
JHKNLHEE_01129 4.1e-242 icd 1.1.1.42 C isocitrate
JHKNLHEE_01130 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
JHKNLHEE_01131 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JHKNLHEE_01132 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
JHKNLHEE_01133 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JHKNLHEE_01134 2.1e-154 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
JHKNLHEE_01135 2.5e-107 ytaF P Probably functions as a manganese efflux pump
JHKNLHEE_01136 2.9e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JHKNLHEE_01137 1.7e-159 ytbE S reductase
JHKNLHEE_01138 2.8e-158 ytbD EGP Major facilitator Superfamily
JHKNLHEE_01139 6.5e-15 ytcD K Transcriptional regulator
JHKNLHEE_01140 2.8e-41 ytcD K Transcriptional regulator
JHKNLHEE_01141 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
JHKNLHEE_01142 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JHKNLHEE_01143 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JHKNLHEE_01144 1.1e-264 dnaB L Membrane attachment protein
JHKNLHEE_01145 3e-173 dnaI L Primosomal protein DnaI
JHKNLHEE_01146 1.6e-109 ytxB S SNARE associated Golgi protein
JHKNLHEE_01147 9.3e-158 ytxC S YtxC-like family
JHKNLHEE_01149 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JHKNLHEE_01150 5.2e-147 ysaA S HAD-hyrolase-like
JHKNLHEE_01151 0.0 lytS 2.7.13.3 T Histidine kinase
JHKNLHEE_01152 3.1e-130 lytT T COG3279 Response regulator of the LytR AlgR family
JHKNLHEE_01153 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
JHKNLHEE_01154 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
JHKNLHEE_01156 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JHKNLHEE_01157 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
JHKNLHEE_01158 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JHKNLHEE_01159 1.7e-44 ysdA S Membrane
JHKNLHEE_01160 9.2e-68 ysdB S Sigma-w pathway protein YsdB
JHKNLHEE_01161 5.8e-205 ysdC G COG1363 Cellulase M and related proteins
JHKNLHEE_01162 7.9e-57 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
JHKNLHEE_01163 1.2e-99 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
JHKNLHEE_01164 1e-292 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
JHKNLHEE_01165 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
JHKNLHEE_01166 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
JHKNLHEE_01167 2.3e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
JHKNLHEE_01168 1.1e-220 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
JHKNLHEE_01169 5.8e-252 araN G carbohydrate transport
JHKNLHEE_01170 1.4e-167 araP G carbohydrate transport
JHKNLHEE_01171 9.9e-144 araQ G transport system permease
JHKNLHEE_01172 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
JHKNLHEE_01173 0.0 cstA T Carbon starvation protein
JHKNLHEE_01175 6.2e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
JHKNLHEE_01176 3.6e-257 glcF C Glycolate oxidase
JHKNLHEE_01177 2.2e-260 glcD 1.1.3.15 C Glycolate oxidase subunit
JHKNLHEE_01178 5.9e-205 ysfB KT regulator
JHKNLHEE_01179 2.6e-32 sspI S Belongs to the SspI family
JHKNLHEE_01180 1.1e-130 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JHKNLHEE_01181 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JHKNLHEE_01182 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JHKNLHEE_01183 2.4e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JHKNLHEE_01184 2e-39 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JHKNLHEE_01185 1.7e-85 cvpA S membrane protein, required for colicin V production
JHKNLHEE_01186 0.0 polX L COG1796 DNA polymerase IV (family X)
JHKNLHEE_01187 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
JHKNLHEE_01188 7.3e-68 yshE S membrane
JHKNLHEE_01189 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
JHKNLHEE_01190 4.7e-100 fadR K Transcriptional regulator
JHKNLHEE_01191 3.5e-135 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
JHKNLHEE_01192 3.8e-134 etfB C Electron transfer flavoprotein
JHKNLHEE_01193 5.1e-176 etfA C Electron transfer flavoprotein
JHKNLHEE_01195 4.1e-302 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
JHKNLHEE_01196 2e-52 trxA O Belongs to the thioredoxin family
JHKNLHEE_01197 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
JHKNLHEE_01198 2e-214 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
JHKNLHEE_01199 1.2e-79 yslB S Protein of unknown function (DUF2507)
JHKNLHEE_01200 2.4e-107 sdhC C succinate dehydrogenase
JHKNLHEE_01201 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
JHKNLHEE_01202 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
JHKNLHEE_01203 6.5e-78 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
JHKNLHEE_01204 1.2e-17 gerE K Transcriptional regulator
JHKNLHEE_01205 3.4e-48 yqaB E IrrE N-terminal-like domain
JHKNLHEE_01206 2.9e-20
JHKNLHEE_01208 7.2e-25 K sequence-specific DNA binding
JHKNLHEE_01209 3.2e-13 K Helix-turn-helix XRE-family like proteins
JHKNLHEE_01211 7e-45 S DNA binding
JHKNLHEE_01212 3.2e-69
JHKNLHEE_01216 3.5e-153 yqaJ L YqaJ-like viral recombinase domain
JHKNLHEE_01217 8.1e-130 recT L RecT family
JHKNLHEE_01218 1.4e-23 L DnaD domain protein
JHKNLHEE_01219 1.9e-71 xkdC L IstB-like ATP binding protein
JHKNLHEE_01221 4.9e-35 S YopX protein
JHKNLHEE_01222 5.7e-53 S Protein of unknown function (DUF1064)
JHKNLHEE_01224 3e-25 yqaO S Phage-like element PBSX protein XtrA
JHKNLHEE_01226 4e-26
JHKNLHEE_01230 1.4e-48 S dUTPase
JHKNLHEE_01231 4e-08 S YopX protein
JHKNLHEE_01236 8.9e-71 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
JHKNLHEE_01238 2.6e-16 K Transcriptional regulator
JHKNLHEE_01239 8.7e-89 S Domain of unknown function (DUF4868)
JHKNLHEE_01240 7.8e-40
JHKNLHEE_01241 2.9e-83 yqaS L DNA packaging
JHKNLHEE_01242 4.4e-185 ps334 S Terminase-like family
JHKNLHEE_01243 2.9e-156 S Phage portal protein, SPP1 Gp6-like
JHKNLHEE_01244 1.3e-57 S Domain of unknown function (DUF4355)
JHKNLHEE_01245 1.2e-123 S Phage capsid family
JHKNLHEE_01247 1.4e-31 S Phage Mu protein F like protein
JHKNLHEE_01248 2.5e-16 S Phage gp6-like head-tail connector protein
JHKNLHEE_01249 3.9e-47
JHKNLHEE_01250 1.5e-22
JHKNLHEE_01251 3.1e-30
JHKNLHEE_01252 1e-102 Z012_02110 S Protein of unknown function (DUF3383)
JHKNLHEE_01253 3e-34
JHKNLHEE_01254 7.6e-14
JHKNLHEE_01255 2.2e-128 N phage tail tape measure protein
JHKNLHEE_01256 3e-40 3.5.1.28 M LysM domain
JHKNLHEE_01257 2.4e-30
JHKNLHEE_01258 4e-88
JHKNLHEE_01259 2.7e-23
JHKNLHEE_01260 1.3e-23 S Protein of unknown function (DUF2634)
JHKNLHEE_01261 1.8e-106 Z012_12235 S homolog of phage Mu protein gp47
JHKNLHEE_01262 3.9e-60
JHKNLHEE_01263 2.8e-38
JHKNLHEE_01265 2.6e-15 xkdX
JHKNLHEE_01266 5.4e-58 S Bacteriophage holin family
JHKNLHEE_01267 6.3e-126 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
JHKNLHEE_01268 4.9e-21
JHKNLHEE_01270 1.3e-44 S YolD-like protein
JHKNLHEE_01271 5.2e-167 L Recombinase
JHKNLHEE_01272 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
JHKNLHEE_01273 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
JHKNLHEE_01274 8.5e-196 gerM S COG5401 Spore germination protein
JHKNLHEE_01275 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JHKNLHEE_01276 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JHKNLHEE_01277 4.1e-92 ysnB S Phosphoesterase
JHKNLHEE_01279 1.6e-130 ysnF S protein conserved in bacteria
JHKNLHEE_01280 9.3e-170 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
JHKNLHEE_01281 2.4e-75 ysnE K acetyltransferase
JHKNLHEE_01283 0.0 ilvB 2.2.1.6 E Acetolactate synthase
JHKNLHEE_01284 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
JHKNLHEE_01285 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JHKNLHEE_01286 1.9e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JHKNLHEE_01287 5.7e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
JHKNLHEE_01288 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JHKNLHEE_01289 4e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JHKNLHEE_01290 1.9e-186 ysoA H Tetratricopeptide repeat
JHKNLHEE_01291 4.1e-226 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
JHKNLHEE_01292 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JHKNLHEE_01293 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
JHKNLHEE_01294 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JHKNLHEE_01295 5.7e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
JHKNLHEE_01296 1.4e-89 ysxD
JHKNLHEE_01297 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JHKNLHEE_01298 3.6e-146 hemX O cytochrome C
JHKNLHEE_01299 8.7e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
JHKNLHEE_01300 2.4e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
JHKNLHEE_01301 2.8e-182 hemB 4.2.1.24 H Belongs to the ALAD family
JHKNLHEE_01302 5.6e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
JHKNLHEE_01303 7.3e-202 spoVID M stage VI sporulation protein D
JHKNLHEE_01304 6.6e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JHKNLHEE_01305 1.6e-25
JHKNLHEE_01306 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
JHKNLHEE_01307 9.6e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
JHKNLHEE_01308 1.5e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
JHKNLHEE_01309 1.2e-161 spoIIB S Sporulation related domain
JHKNLHEE_01310 1.1e-101 maf D septum formation protein Maf
JHKNLHEE_01311 5.9e-126 radC E Belongs to the UPF0758 family
JHKNLHEE_01312 1.8e-184 mreB D Rod shape-determining protein MreB
JHKNLHEE_01313 1.1e-156 mreC M Involved in formation and maintenance of cell shape
JHKNLHEE_01314 4.2e-84 mreD M shape-determining protein
JHKNLHEE_01315 7.1e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
JHKNLHEE_01316 4.7e-143 minD D Belongs to the ParA family
JHKNLHEE_01317 1.1e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
JHKNLHEE_01318 2e-160 spoIVFB S Stage IV sporulation protein
JHKNLHEE_01319 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
JHKNLHEE_01320 4.1e-56 ysxB J ribosomal protein
JHKNLHEE_01321 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
JHKNLHEE_01322 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
JHKNLHEE_01323 4.3e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JHKNLHEE_01324 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
JHKNLHEE_01325 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
JHKNLHEE_01326 2.3e-93 niaR S small molecule binding protein (contains 3H domain)
JHKNLHEE_01327 5.9e-227 nifS 2.8.1.7 E Cysteine desulfurase
JHKNLHEE_01328 3.4e-302 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
JHKNLHEE_01329 2.9e-154 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
JHKNLHEE_01330 9.1e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JHKNLHEE_01331 5.2e-135 safA M spore coat assembly protein SafA
JHKNLHEE_01332 6e-47 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
JHKNLHEE_01333 6.1e-126 yebC K transcriptional regulatory protein
JHKNLHEE_01334 4.5e-261 alsT E Sodium alanine symporter
JHKNLHEE_01335 1.5e-50 S Family of unknown function (DUF5412)
JHKNLHEE_01337 6.5e-119 yrzF T serine threonine protein kinase
JHKNLHEE_01338 4.8e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
JHKNLHEE_01339 1.5e-252 csbX EGP Major facilitator Superfamily
JHKNLHEE_01340 4.8e-93 bofC S BofC C-terminal domain
JHKNLHEE_01341 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
JHKNLHEE_01342 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
JHKNLHEE_01343 2.6e-18 yrzS S Protein of unknown function (DUF2905)
JHKNLHEE_01344 5.7e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JHKNLHEE_01345 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
JHKNLHEE_01346 8e-39 yajC U Preprotein translocase subunit YajC
JHKNLHEE_01347 3.8e-73 yrzE S Protein of unknown function (DUF3792)
JHKNLHEE_01348 6.6e-111 yrbG S membrane
JHKNLHEE_01349 2.4e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JHKNLHEE_01350 1.6e-48 yrzD S Post-transcriptional regulator
JHKNLHEE_01351 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JHKNLHEE_01352 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
JHKNLHEE_01353 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
JHKNLHEE_01354 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
JHKNLHEE_01355 2.3e-90 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JHKNLHEE_01356 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JHKNLHEE_01357 1.9e-69 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
JHKNLHEE_01358 5.9e-259 lytH 3.5.1.28 M COG3103 SH3 domain protein
JHKNLHEE_01360 4.8e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
JHKNLHEE_01361 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JHKNLHEE_01362 9e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
JHKNLHEE_01363 1.7e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
JHKNLHEE_01364 1.2e-70 cymR K Transcriptional regulator
JHKNLHEE_01365 5.7e-211 iscS 2.8.1.7 E Cysteine desulfurase
JHKNLHEE_01366 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
JHKNLHEE_01367 1.4e-15 S COG0457 FOG TPR repeat
JHKNLHEE_01368 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
JHKNLHEE_01369 6.6e-81 yrrD S protein conserved in bacteria
JHKNLHEE_01370 9.8e-31 yrzR
JHKNLHEE_01371 8e-08 S Protein of unknown function (DUF3918)
JHKNLHEE_01372 7.6e-107 glnP P ABC transporter
JHKNLHEE_01373 2.3e-108 gluC P ABC transporter
JHKNLHEE_01374 2.5e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
JHKNLHEE_01375 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
JHKNLHEE_01376 2.5e-168 yrrI S AI-2E family transporter
JHKNLHEE_01377 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JHKNLHEE_01378 1.7e-41 yrzL S Belongs to the UPF0297 family
JHKNLHEE_01379 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JHKNLHEE_01380 1.2e-45 yrzB S Belongs to the UPF0473 family
JHKNLHEE_01381 4.8e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JHKNLHEE_01382 2.3e-119 yrrM 2.1.1.104 S O-methyltransferase
JHKNLHEE_01383 7.8e-174 yegQ O Peptidase U32
JHKNLHEE_01384 1.4e-245 yegQ O COG0826 Collagenase and related proteases
JHKNLHEE_01385 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
JHKNLHEE_01386 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
JHKNLHEE_01387 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
JHKNLHEE_01388 4.2e-63 yrrS S Protein of unknown function (DUF1510)
JHKNLHEE_01389 1e-25 yrzA S Protein of unknown function (DUF2536)
JHKNLHEE_01390 1.2e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
JHKNLHEE_01391 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JHKNLHEE_01392 6.1e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
JHKNLHEE_01393 9.1e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
JHKNLHEE_01394 4.6e-35 yrhC S YrhC-like protein
JHKNLHEE_01395 2.1e-77 yrhD S Protein of unknown function (DUF1641)
JHKNLHEE_01396 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
JHKNLHEE_01397 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
JHKNLHEE_01399 1.8e-142 focA P Formate nitrite
JHKNLHEE_01402 1.4e-95 yrhH Q methyltransferase
JHKNLHEE_01403 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
JHKNLHEE_01404 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
JHKNLHEE_01405 9e-44 yrhK S YrhK-like protein
JHKNLHEE_01406 0.0 yrhL I Acyltransferase family
JHKNLHEE_01407 3.2e-150 rsiV S Protein of unknown function (DUF3298)
JHKNLHEE_01408 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
JHKNLHEE_01409 3.5e-149 yrhO K Archaeal transcriptional regulator TrmB
JHKNLHEE_01410 1.1e-105 yrhP E LysE type translocator
JHKNLHEE_01411 1.5e-253 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
JHKNLHEE_01412 0.0 levR K PTS system fructose IIA component
JHKNLHEE_01413 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
JHKNLHEE_01414 2.4e-81 levE 2.7.1.202 G PTS system mannose fructose sorbose family
JHKNLHEE_01415 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
JHKNLHEE_01416 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
JHKNLHEE_01417 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
JHKNLHEE_01418 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
JHKNLHEE_01419 1.8e-195 adhA 1.1.1.1 C alcohol dehydrogenase
JHKNLHEE_01420 1.3e-25 yphJ 4.1.1.44 S peroxiredoxin activity
JHKNLHEE_01421 4.3e-47 yraB K helix_turn_helix, mercury resistance
JHKNLHEE_01422 4.8e-123 yrpD S Domain of unknown function, YrpD
JHKNLHEE_01423 4.1e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
JHKNLHEE_01424 1e-190 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
JHKNLHEE_01425 5.5e-166 aadK G Streptomycin adenylyltransferase
JHKNLHEE_01426 1.2e-205 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
JHKNLHEE_01427 1.2e-89 ydaK T Diguanylate cyclase, GGDEF domain
JHKNLHEE_01428 3.9e-30 ydaK T Diguanylate cyclase, GGDEF domain
JHKNLHEE_01429 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
JHKNLHEE_01430 4.5e-233 ydaM M Glycosyl transferase family group 2
JHKNLHEE_01431 1e-185 ydaN S Bacterial cellulose synthase subunit
JHKNLHEE_01432 3.5e-186 ydaN S Bacterial cellulose synthase subunit
JHKNLHEE_01433 0.0 ydaO E amino acid
JHKNLHEE_01434 5.2e-75 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
JHKNLHEE_01435 2.3e-287 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
JHKNLHEE_01436 2.9e-19 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
JHKNLHEE_01437 4.7e-39
JHKNLHEE_01438 1e-224 mntH P H( )-stimulated, divalent metal cation uptake system
JHKNLHEE_01440 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
JHKNLHEE_01441 2.7e-146 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
JHKNLHEE_01443 2.6e-58 ydbB G Cupin domain
JHKNLHEE_01444 2.6e-61 ydbC S Domain of unknown function (DUF4937
JHKNLHEE_01445 1.2e-138 ydbD P Catalase
JHKNLHEE_01446 3.9e-198 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
JHKNLHEE_01447 4.8e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
JHKNLHEE_01448 1.1e-119 dctR T COG4565 Response regulator of citrate malate metabolism
JHKNLHEE_01449 3.1e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
JHKNLHEE_01450 9.7e-181 ydbI S AI-2E family transporter
JHKNLHEE_01452 1.8e-170 ydbJ V ABC transporter, ATP-binding protein
JHKNLHEE_01453 3e-123 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
JHKNLHEE_01454 2.7e-52 ydbL
JHKNLHEE_01455 4.4e-219 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
JHKNLHEE_01456 1.1e-18 S Fur-regulated basic protein B
JHKNLHEE_01457 2.2e-07 S Fur-regulated basic protein A
JHKNLHEE_01458 2.1e-149 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JHKNLHEE_01459 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
JHKNLHEE_01460 3.9e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
JHKNLHEE_01461 9.6e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
JHKNLHEE_01462 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
JHKNLHEE_01463 2.1e-82 ydbS S Bacterial PH domain
JHKNLHEE_01464 9.6e-259 ydbT S Membrane
JHKNLHEE_01465 6.9e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
JHKNLHEE_01466 8e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
JHKNLHEE_01467 8.5e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
JHKNLHEE_01468 4.3e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JHKNLHEE_01469 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
JHKNLHEE_01470 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
JHKNLHEE_01471 1.3e-143 rsbR T Positive regulator of sigma-B
JHKNLHEE_01472 5.2e-57 rsbS T antagonist
JHKNLHEE_01473 2.9e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
JHKNLHEE_01474 7.1e-189 rsbU 3.1.3.3 KT phosphatase
JHKNLHEE_01475 3e-51 rsbV T Belongs to the anti-sigma-factor antagonist family
JHKNLHEE_01476 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
JHKNLHEE_01477 1.3e-137 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JHKNLHEE_01478 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
JHKNLHEE_01479 0.0 yhgF K COG2183 Transcriptional accessory protein
JHKNLHEE_01480 6.2e-84 ydcK S Belongs to the SprT family
JHKNLHEE_01488 3.2e-57 2.3.1.183 M Acetyltransferase (GNAT) domain
JHKNLHEE_01489 1.4e-200 O Pyridine nucleotide-disulphide oxidoreductase
JHKNLHEE_01490 5.2e-45 arsR K ArsR family transcriptional regulator
JHKNLHEE_01491 2.8e-52 arsR K transcriptional
JHKNLHEE_01492 3.9e-216 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JHKNLHEE_01493 9.2e-74 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
JHKNLHEE_01494 5e-204 L Belongs to the 'phage' integrase family
JHKNLHEE_01495 3.1e-84 immA E IrrE N-terminal-like domain
JHKNLHEE_01496 1.4e-60 yvaO K Transcriptional
JHKNLHEE_01497 3.1e-16
JHKNLHEE_01498 7.8e-39
JHKNLHEE_01500 1.7e-63 S Bacterial protein of unknown function (DUF961)
JHKNLHEE_01501 6.5e-222 ydcQ D Ftsk spoiiie family protein
JHKNLHEE_01502 5.3e-203 nicK L Replication initiation factor
JHKNLHEE_01503 4e-16 S Domain of Unknown Function with PDB structure (DUF3850)
JHKNLHEE_01505 1.6e-32 yddA
JHKNLHEE_01506 1.8e-166 yddB S Conjugative transposon protein TcpC
JHKNLHEE_01507 4.4e-39 yddC
JHKNLHEE_01508 4.2e-92 yddD S TcpE family
JHKNLHEE_01509 0.0 yddE S AAA-like domain
JHKNLHEE_01510 6.3e-51 S Domain of unknown function (DUF1874)
JHKNLHEE_01511 0.0 yddG S maturation of SSU-rRNA
JHKNLHEE_01512 1.5e-186 yddH CBM50 M Lysozyme-like
JHKNLHEE_01513 1.8e-84 yddI
JHKNLHEE_01514 5.1e-63 S Domain of unknown function with cystatin-like fold (DUF4467)
JHKNLHEE_01515 1.2e-73 S response regulator aspartate phosphatase
JHKNLHEE_01517 3.9e-73
JHKNLHEE_01519 1.7e-75 rimJ2 J Acetyltransferase (GNAT) domain
JHKNLHEE_01520 2.5e-11 tnpIS3 L Transposase
JHKNLHEE_01521 1.3e-90 ywjG S Domain of unknown function (DUF2529)
JHKNLHEE_01522 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
JHKNLHEE_01523 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
JHKNLHEE_01524 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JHKNLHEE_01525 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JHKNLHEE_01526 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
JHKNLHEE_01527 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JHKNLHEE_01528 1.1e-32 rpmE J Binds the 23S rRNA
JHKNLHEE_01529 1.6e-103 tdk 2.7.1.21 F thymidine kinase
JHKNLHEE_01530 0.0 sfcA 1.1.1.38 C malic enzyme
JHKNLHEE_01531 8.6e-160 ywkB S Membrane transport protein
JHKNLHEE_01532 1.2e-89 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
JHKNLHEE_01533 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JHKNLHEE_01534 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JHKNLHEE_01535 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
JHKNLHEE_01537 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
JHKNLHEE_01538 6.1e-112 spoIIR S stage II sporulation protein R
JHKNLHEE_01539 2.1e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
JHKNLHEE_01540 1.3e-193 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
JHKNLHEE_01541 1.7e-91 mntP P Probably functions as a manganese efflux pump
JHKNLHEE_01542 4e-75 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JHKNLHEE_01543 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
JHKNLHEE_01544 1.6e-94 ywlG S Belongs to the UPF0340 family
JHKNLHEE_01545 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JHKNLHEE_01546 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JHKNLHEE_01547 2.5e-62 atpI S ATP synthase
JHKNLHEE_01548 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
JHKNLHEE_01549 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JHKNLHEE_01550 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JHKNLHEE_01551 2e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JHKNLHEE_01552 4.5e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JHKNLHEE_01553 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JHKNLHEE_01554 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JHKNLHEE_01555 8.5e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
JHKNLHEE_01556 1.4e-86 ywmA
JHKNLHEE_01557 1.3e-32 ywzB S membrane
JHKNLHEE_01558 9e-133 ywmB S TATA-box binding
JHKNLHEE_01559 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JHKNLHEE_01560 7.5e-178 spoIID D Stage II sporulation protein D
JHKNLHEE_01561 3.3e-121 ywmC S protein containing a von Willebrand factor type A (vWA) domain
JHKNLHEE_01562 2.7e-120 ywmD S protein containing a von Willebrand factor type A (vWA) domain
JHKNLHEE_01564 1.3e-145 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JHKNLHEE_01565 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JHKNLHEE_01566 1.3e-103 S response regulator aspartate phosphatase
JHKNLHEE_01567 5.1e-84 ywmF S Peptidase M50
JHKNLHEE_01568 1.1e-10 csbD K CsbD-like
JHKNLHEE_01569 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
JHKNLHEE_01570 3.8e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
JHKNLHEE_01571 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
JHKNLHEE_01572 6.3e-64 ywnA K Transcriptional regulator
JHKNLHEE_01573 1.6e-114 ywnB S NAD(P)H-binding
JHKNLHEE_01574 2.6e-59 ywnC S Family of unknown function (DUF5362)
JHKNLHEE_01575 7.7e-143 mta K transcriptional
JHKNLHEE_01576 4.6e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JHKNLHEE_01577 2.2e-70 ywnF S Family of unknown function (DUF5392)
JHKNLHEE_01578 1.4e-10 ywnC S Family of unknown function (DUF5362)
JHKNLHEE_01579 2e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
JHKNLHEE_01580 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
JHKNLHEE_01581 5.1e-72 ywnJ S VanZ like family
JHKNLHEE_01582 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
JHKNLHEE_01583 1.6e-58 nrgB K Belongs to the P(II) protein family
JHKNLHEE_01584 2.5e-225 amt P Ammonium transporter
JHKNLHEE_01585 2.2e-76
JHKNLHEE_01586 8.9e-104 phzA Q Isochorismatase family
JHKNLHEE_01587 1.6e-239 ywoD EGP Major facilitator superfamily
JHKNLHEE_01588 5.2e-281 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
JHKNLHEE_01589 1.2e-231 ywoF P Right handed beta helix region
JHKNLHEE_01590 2.7e-211 ywoG EGP Major facilitator Superfamily
JHKNLHEE_01591 2.1e-70 ywoH K COG1846 Transcriptional regulators
JHKNLHEE_01592 3e-44 spoIIID K Stage III sporulation protein D
JHKNLHEE_01593 3.5e-180 mbl D Rod shape-determining protein
JHKNLHEE_01594 6.9e-126 flhO N flagellar basal body
JHKNLHEE_01595 2.6e-141 flhP N flagellar basal body
JHKNLHEE_01596 5.3e-113 S aspartate phosphatase
JHKNLHEE_01597 2.3e-54 S aspartate phosphatase
JHKNLHEE_01598 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
JHKNLHEE_01599 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
JHKNLHEE_01600 9.2e-145 ywpD T Histidine kinase
JHKNLHEE_01601 5.4e-49 srtA 3.4.22.70 M Sortase family
JHKNLHEE_01602 2.9e-76 ctsR K Belongs to the CtsR family
JHKNLHEE_01603 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
JHKNLHEE_01604 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
JHKNLHEE_01605 0.0 clpC O Belongs to the ClpA ClpB family
JHKNLHEE_01606 6.2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JHKNLHEE_01607 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
JHKNLHEE_01608 1.7e-196 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
JHKNLHEE_01609 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
JHKNLHEE_01610 1.2e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
JHKNLHEE_01611 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JHKNLHEE_01612 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
JHKNLHEE_01613 2.4e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
JHKNLHEE_01614 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JHKNLHEE_01615 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JHKNLHEE_01616 1.2e-88 yacP S RNA-binding protein containing a PIN domain
JHKNLHEE_01617 4.4e-115 sigH K Belongs to the sigma-70 factor family
JHKNLHEE_01618 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
JHKNLHEE_01619 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
JHKNLHEE_01620 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JHKNLHEE_01621 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
JHKNLHEE_01622 8.7e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JHKNLHEE_01623 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
JHKNLHEE_01624 1.2e-106 rsmC 2.1.1.172 J Methyltransferase
JHKNLHEE_01625 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JHKNLHEE_01626 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JHKNLHEE_01627 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
JHKNLHEE_01628 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JHKNLHEE_01629 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
JHKNLHEE_01630 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JHKNLHEE_01631 8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JHKNLHEE_01632 1.7e-184 ybaC 3.4.11.5 S Alpha/beta hydrolase family
JHKNLHEE_01633 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
JHKNLHEE_01634 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JHKNLHEE_01635 3e-105 rplD J Forms part of the polypeptide exit tunnel
JHKNLHEE_01636 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
JHKNLHEE_01637 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JHKNLHEE_01638 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JHKNLHEE_01639 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JHKNLHEE_01640 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JHKNLHEE_01641 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JHKNLHEE_01642 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
JHKNLHEE_01643 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JHKNLHEE_01644 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JHKNLHEE_01645 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JHKNLHEE_01646 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JHKNLHEE_01647 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JHKNLHEE_01648 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JHKNLHEE_01649 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JHKNLHEE_01650 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JHKNLHEE_01651 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JHKNLHEE_01652 1.9e-23 rpmD J Ribosomal protein L30
JHKNLHEE_01653 1.8e-72 rplO J binds to the 23S rRNA
JHKNLHEE_01654 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
JHKNLHEE_01655 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
JHKNLHEE_01656 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
JHKNLHEE_01657 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JHKNLHEE_01658 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
JHKNLHEE_01659 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JHKNLHEE_01660 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JHKNLHEE_01661 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JHKNLHEE_01662 3.6e-58 rplQ J Ribosomal protein L17
JHKNLHEE_01663 1.9e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JHKNLHEE_01664 1.4e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JHKNLHEE_01665 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JHKNLHEE_01666 8.2e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
JHKNLHEE_01667 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JHKNLHEE_01668 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
JHKNLHEE_01669 1.2e-143 ybaJ Q Methyltransferase domain
JHKNLHEE_01670 3.5e-71 ybaK S Protein of unknown function (DUF2521)
JHKNLHEE_01671 2.8e-131 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
JHKNLHEE_01672 5.1e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
JHKNLHEE_01673 1.2e-84 gerD
JHKNLHEE_01674 3.9e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
JHKNLHEE_01675 1.8e-139 pdaB 3.5.1.104 G Polysaccharide deacetylase
JHKNLHEE_01676 3.5e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
JHKNLHEE_01677 8.8e-110 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
JHKNLHEE_01678 1.2e-73 sipT 3.4.21.89 U Belongs to the peptidase S26 family
JHKNLHEE_01679 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
JHKNLHEE_01680 1.1e-200 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
JHKNLHEE_01681 3.4e-208 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
JHKNLHEE_01682 5.7e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
JHKNLHEE_01683 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
JHKNLHEE_01684 7.3e-56
JHKNLHEE_01685 1.6e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
JHKNLHEE_01686 1.1e-305 ycnJ P protein, homolog of Cu resistance protein CopC
JHKNLHEE_01687 6.6e-97 ycnI S protein conserved in bacteria
JHKNLHEE_01688 1.4e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JHKNLHEE_01689 6.1e-149 glcU U Glucose uptake
JHKNLHEE_01690 1.1e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
JHKNLHEE_01691 1.4e-245 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JHKNLHEE_01692 4e-270 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JHKNLHEE_01693 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
JHKNLHEE_01694 1.6e-45 ycnE S Monooxygenase
JHKNLHEE_01695 2.2e-134 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
JHKNLHEE_01696 5.5e-153 ycnC K Transcriptional regulator
JHKNLHEE_01697 4.1e-251 ycnB EGP Major facilitator Superfamily
JHKNLHEE_01698 9.4e-167 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
JHKNLHEE_01699 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
JHKNLHEE_01700 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JHKNLHEE_01701 4.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JHKNLHEE_01702 4.1e-232 lysC 2.7.2.4 E Belongs to the aspartokinase family
JHKNLHEE_01706 1.2e-70 S aspartate phosphatase
JHKNLHEE_01707 8.3e-260 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
JHKNLHEE_01708 2.1e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JHKNLHEE_01709 4e-201 yclI V ABC transporter (permease) YclI
JHKNLHEE_01710 7.3e-121 yclH P ABC transporter
JHKNLHEE_01711 1.3e-194 gerKB F Spore germination protein
JHKNLHEE_01712 8e-227 gerKC S spore germination
JHKNLHEE_01713 7.8e-278 gerKA EG Spore germination protein
JHKNLHEE_01715 2e-292 yclG M Pectate lyase superfamily protein
JHKNLHEE_01716 1.2e-261 dtpT E amino acid peptide transporter
JHKNLHEE_01717 7.1e-158 yclE 3.4.11.5 S Alpha beta hydrolase
JHKNLHEE_01718 3.9e-38 yclD
JHKNLHEE_01719 8.9e-39 bsdD 4.1.1.61 S response to toxic substance
JHKNLHEE_01720 1.2e-282 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
JHKNLHEE_01721 5.4e-107 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
JHKNLHEE_01722 1.9e-161 bsdA K LysR substrate binding domain
JHKNLHEE_01723 1.3e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
JHKNLHEE_01724 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
JHKNLHEE_01725 4.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
JHKNLHEE_01726 1.7e-114 yczE S membrane
JHKNLHEE_01727 1.2e-112 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
JHKNLHEE_01728 6.2e-249 ycxD K GntR family transcriptional regulator
JHKNLHEE_01729 1.3e-160 ycxC EG EamA-like transporter family
JHKNLHEE_01730 2.1e-89 S YcxB-like protein
JHKNLHEE_01731 1.4e-226 EGP Major Facilitator Superfamily
JHKNLHEE_01732 2.2e-139 srfAD Q thioesterase
JHKNLHEE_01733 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
JHKNLHEE_01734 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JHKNLHEE_01735 2.6e-208 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JHKNLHEE_01736 6.8e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
JHKNLHEE_01737 2.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
JHKNLHEE_01738 4.4e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
JHKNLHEE_01739 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
JHKNLHEE_01740 4.5e-88 yaiI S Belongs to the UPF0178 family
JHKNLHEE_01741 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
JHKNLHEE_01742 4.5e-112 ccpN K CBS domain
JHKNLHEE_01743 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
JHKNLHEE_01744 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
JHKNLHEE_01745 9e-144 recO L Involved in DNA repair and RecF pathway recombination
JHKNLHEE_01746 8.4e-19 S YqzL-like protein
JHKNLHEE_01747 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JHKNLHEE_01748 3.5e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
JHKNLHEE_01749 2.5e-59 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
JHKNLHEE_01750 8.8e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JHKNLHEE_01751 0.0 yqfF S membrane-associated HD superfamily hydrolase
JHKNLHEE_01753 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
JHKNLHEE_01754 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
JHKNLHEE_01755 2.7e-45 yqfC S sporulation protein YqfC
JHKNLHEE_01756 4.3e-23 yqfB
JHKNLHEE_01757 4.3e-122 yqfA S UPF0365 protein
JHKNLHEE_01758 2.3e-227 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
JHKNLHEE_01759 2.5e-61 yqeY S Yqey-like protein
JHKNLHEE_01760 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
JHKNLHEE_01761 1.5e-156 yqeW P COG1283 Na phosphate symporter
JHKNLHEE_01762 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
JHKNLHEE_01763 3.6e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
JHKNLHEE_01764 5.4e-175 prmA J Methylates ribosomal protein L11
JHKNLHEE_01765 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
JHKNLHEE_01766 0.0 dnaK O Heat shock 70 kDa protein
JHKNLHEE_01767 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JHKNLHEE_01768 6.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
JHKNLHEE_01769 1.7e-215 hemN H Involved in the biosynthesis of porphyrin-containing compound
JHKNLHEE_01770 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
JHKNLHEE_01771 7.2e-53 yqxA S Protein of unknown function (DUF3679)
JHKNLHEE_01772 1.5e-222 spoIIP M stage II sporulation protein P
JHKNLHEE_01773 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
JHKNLHEE_01774 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
JHKNLHEE_01775 6.2e-188 holA 2.7.7.7 L DNA polymerase III delta subunit
JHKNLHEE_01776 4.1e-15 S YqzM-like protein
JHKNLHEE_01777 0.0 comEC S Competence protein ComEC
JHKNLHEE_01778 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
JHKNLHEE_01779 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
JHKNLHEE_01780 2.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JHKNLHEE_01781 3.2e-138 yqeM Q Methyltransferase
JHKNLHEE_01782 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
JHKNLHEE_01783 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
JHKNLHEE_01784 3.8e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JHKNLHEE_01785 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
JHKNLHEE_01786 5.1e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JHKNLHEE_01787 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
JHKNLHEE_01788 5.3e-95 yqeG S hydrolase of the HAD superfamily
JHKNLHEE_01790 1.4e-141 yqeF E GDSL-like Lipase/Acylhydrolase
JHKNLHEE_01791 5.2e-96 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
JHKNLHEE_01792 8.8e-105 yqeD S SNARE associated Golgi protein
JHKNLHEE_01793 5e-170 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
JHKNLHEE_01794 6.3e-131 yqeB
JHKNLHEE_01795 1.6e-35 nucB M Deoxyribonuclease NucA/NucB
JHKNLHEE_01796 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JHKNLHEE_01797 3.4e-31 csfB S Inhibitor of sigma-G Gin
JHKNLHEE_01798 2e-101 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
JHKNLHEE_01799 2.2e-202 yaaN P Belongs to the TelA family
JHKNLHEE_01800 1.8e-270 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
JHKNLHEE_01801 3.1e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JHKNLHEE_01802 2.2e-54 yaaQ S protein conserved in bacteria
JHKNLHEE_01803 1e-70 yaaR S protein conserved in bacteria
JHKNLHEE_01804 2.2e-182 holB 2.7.7.7 L DNA polymerase III
JHKNLHEE_01805 6.1e-146 yaaT S stage 0 sporulation protein
JHKNLHEE_01806 4.8e-31 yabA L Involved in initiation control of chromosome replication
JHKNLHEE_01807 1.2e-137 yabB 2.1.1.223 S Conserved hypothetical protein 95
JHKNLHEE_01808 1.5e-49 yazA L endonuclease containing a URI domain
JHKNLHEE_01809 4.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JHKNLHEE_01810 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
JHKNLHEE_01811 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JHKNLHEE_01812 7.6e-143 tatD L hydrolase, TatD
JHKNLHEE_01813 5.8e-167 rpfB GH23 T protein conserved in bacteria
JHKNLHEE_01814 7.9e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JHKNLHEE_01815 4.2e-153 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
JHKNLHEE_01816 3.7e-133 yabG S peptidase
JHKNLHEE_01817 7.8e-39 veg S protein conserved in bacteria
JHKNLHEE_01818 8.3e-27 sspF S DNA topological change
JHKNLHEE_01819 2.7e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JHKNLHEE_01820 5.9e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
JHKNLHEE_01821 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
JHKNLHEE_01822 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
JHKNLHEE_01823 1.2e-228 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JHKNLHEE_01824 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JHKNLHEE_01825 1.5e-96 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JHKNLHEE_01826 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
JHKNLHEE_01827 2.4e-39 yabK S Peptide ABC transporter permease
JHKNLHEE_01828 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JHKNLHEE_01829 1.5e-92 spoVT K stage V sporulation protein
JHKNLHEE_01830 7.8e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JHKNLHEE_01831 1.1e-243 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
JHKNLHEE_01832 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
JHKNLHEE_01833 1.5e-49 yabP S Sporulation protein YabP
JHKNLHEE_01834 2.5e-107 yabQ S spore cortex biosynthesis protein
JHKNLHEE_01835 1.1e-44 divIC D Septum formation initiator
JHKNLHEE_01836 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
JHKNLHEE_01839 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
JHKNLHEE_01840 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
JHKNLHEE_01841 2.9e-182 KLT serine threonine protein kinase
JHKNLHEE_01842 8.5e-273 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
JHKNLHEE_01843 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
JHKNLHEE_01844 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JHKNLHEE_01845 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JHKNLHEE_01846 8.4e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JHKNLHEE_01847 5.2e-159 yacD 5.2.1.8 O peptidyl-prolyl isomerase
JHKNLHEE_01848 2.8e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
JHKNLHEE_01849 2.2e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JHKNLHEE_01850 4.3e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
JHKNLHEE_01851 3.7e-165 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
JHKNLHEE_01852 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JHKNLHEE_01853 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JHKNLHEE_01854 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JHKNLHEE_01855 4.1e-30 yazB K transcriptional
JHKNLHEE_01856 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JHKNLHEE_01857 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
JHKNLHEE_01858 1.7e-29 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
JHKNLHEE_01859 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
JHKNLHEE_01860 5.7e-50 yviE
JHKNLHEE_01861 3e-154 flgL N Belongs to the bacterial flagellin family
JHKNLHEE_01862 1.2e-264 flgK N flagellar hook-associated protein
JHKNLHEE_01863 9.2e-78 flgN NOU FlgN protein
JHKNLHEE_01864 1e-38 flgM KNU Negative regulator of flagellin synthesis
JHKNLHEE_01865 2e-73 yvyF S flagellar protein
JHKNLHEE_01866 1.2e-126 comFC S Phosphoribosyl transferase domain
JHKNLHEE_01867 8.3e-45 comFB S Late competence development protein ComFB
JHKNLHEE_01868 6.9e-267 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JHKNLHEE_01869 4.8e-154 degV S protein conserved in bacteria
JHKNLHEE_01870 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JHKNLHEE_01871 1.5e-182 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
JHKNLHEE_01872 5.9e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
JHKNLHEE_01873 6e-163 yvhJ K Transcriptional regulator
JHKNLHEE_01874 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
JHKNLHEE_01875 1.3e-234 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
JHKNLHEE_01876 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
JHKNLHEE_01877 3.9e-114 tuaF M protein involved in exopolysaccharide biosynthesis
JHKNLHEE_01878 2.7e-261 tuaE M Teichuronic acid biosynthesis protein
JHKNLHEE_01879 4.9e-257 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JHKNLHEE_01880 1.2e-219 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
JHKNLHEE_01881 4.4e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JHKNLHEE_01882 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
JHKNLHEE_01883 5.6e-267 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
JHKNLHEE_01884 0.0 lytB 3.5.1.28 D Stage II sporulation protein
JHKNLHEE_01885 6e-38
JHKNLHEE_01886 4e-162 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
JHKNLHEE_01887 1e-215 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
JHKNLHEE_01888 7.6e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
JHKNLHEE_01889 2.2e-277 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
JHKNLHEE_01890 1.1e-150 tagG GM Transport permease protein
JHKNLHEE_01891 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JHKNLHEE_01892 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
JHKNLHEE_01893 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
JHKNLHEE_01894 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
JHKNLHEE_01895 1.5e-214 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JHKNLHEE_01896 1.2e-260
JHKNLHEE_01897 5.2e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
JHKNLHEE_01898 6.7e-189 pmi 5.3.1.8 G mannose-6-phosphate isomerase
JHKNLHEE_01899 5.4e-196 gerBA EG Spore germination protein
JHKNLHEE_01900 3.6e-141 gerBB E Spore germination protein
JHKNLHEE_01901 1.4e-211 gerAC S Spore germination protein
JHKNLHEE_01902 3.9e-246 ywtG EGP Major facilitator Superfamily
JHKNLHEE_01903 2.4e-170 ywtF K Transcriptional regulator
JHKNLHEE_01904 1e-159 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
JHKNLHEE_01905 9.8e-161 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
JHKNLHEE_01906 5e-14 S D-Ala-teichoic acid biosynthesis protein
JHKNLHEE_01907 5.1e-292 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JHKNLHEE_01908 8e-232 dltB M membrane protein involved in D-alanine export
JHKNLHEE_01909 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JHKNLHEE_01910 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JHKNLHEE_01911 6.2e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
JHKNLHEE_01912 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
JHKNLHEE_01913 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
JHKNLHEE_01914 5.6e-37 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
JHKNLHEE_01915 4.5e-247 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JHKNLHEE_01916 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
JHKNLHEE_01917 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
JHKNLHEE_01918 1.1e-19 yxzF
JHKNLHEE_01919 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
JHKNLHEE_01920 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
JHKNLHEE_01921 2.6e-44 yxlH EGP Major facilitator Superfamily
JHKNLHEE_01922 2.9e-157 yxlH EGP Major facilitator Superfamily
JHKNLHEE_01923 1.2e-138 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
JHKNLHEE_01924 2.1e-146 yxlF V ABC transporter, ATP-binding protein
JHKNLHEE_01925 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
JHKNLHEE_01926 4.9e-28
JHKNLHEE_01927 2.5e-39 yxlC S Family of unknown function (DUF5345)
JHKNLHEE_01928 4e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
JHKNLHEE_01929 1.5e-253 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
JHKNLHEE_01930 1.9e-155 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JHKNLHEE_01931 0.0 cydD V ATP-binding protein
JHKNLHEE_01932 1.7e-310 cydD V ATP-binding
JHKNLHEE_01933 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
JHKNLHEE_01934 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
JHKNLHEE_01935 1.5e-229 cimH C COG3493 Na citrate symporter
JHKNLHEE_01936 1e-309 3.4.24.84 O Peptidase family M48
JHKNLHEE_01938 8.9e-153 yxkH G Polysaccharide deacetylase
JHKNLHEE_01939 5.9e-205 msmK P Belongs to the ABC transporter superfamily
JHKNLHEE_01940 4.5e-163 lrp QT PucR C-terminal helix-turn-helix domain
JHKNLHEE_01941 6.3e-271 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
JHKNLHEE_01942 4.7e-146 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
JHKNLHEE_01943 2.4e-73 yxkC S Domain of unknown function (DUF4352)
JHKNLHEE_01944 1e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
JHKNLHEE_01945 3.4e-77 S Protein of unknown function (DUF1453)
JHKNLHEE_01946 8.9e-186 yxjM T Signal transduction histidine kinase
JHKNLHEE_01947 1.9e-113 K helix_turn_helix, Lux Regulon
JHKNLHEE_01948 6.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
JHKNLHEE_01951 1.6e-85 yxjI S LURP-one-related
JHKNLHEE_01952 3.9e-220 yxjG 2.1.1.14 E Methionine synthase
JHKNLHEE_01953 8.2e-218 yxjG 2.1.1.14 E Methionine synthase
JHKNLHEE_01954 1.8e-90 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
JHKNLHEE_01955 2.1e-26 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
JHKNLHEE_01956 2e-115 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
JHKNLHEE_01957 9e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JHKNLHEE_01958 1.6e-250 yxjC EG COG2610 H gluconate symporter and related permeases
JHKNLHEE_01959 7.1e-158 rlmA 2.1.1.187 Q Methyltransferase domain
JHKNLHEE_01960 1.9e-74
JHKNLHEE_01962 1.4e-27 K Cro/C1-type HTH DNA-binding domain
JHKNLHEE_01968 3.1e-103
JHKNLHEE_01973 5.4e-195 L Belongs to the 'phage' integrase family
JHKNLHEE_01974 1.1e-261 S DNA-sulfur modification-associated
JHKNLHEE_01975 4.6e-177
JHKNLHEE_01976 1.1e-33 K Transcriptional regulator
JHKNLHEE_01980 6.2e-42
JHKNLHEE_01989 1.2e-22
JHKNLHEE_01993 1.6e-72
JHKNLHEE_01996 1.8e-87
JHKNLHEE_01998 8.3e-27
JHKNLHEE_02000 3.7e-148 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
JHKNLHEE_02001 1.5e-126 yoqW S Belongs to the SOS response-associated peptidase family
JHKNLHEE_02003 1e-159
JHKNLHEE_02006 5.7e-144 S Pfam:DUF867
JHKNLHEE_02007 0.0 M Parallel beta-helix repeats
JHKNLHEE_02011 3.6e-155
JHKNLHEE_02012 7.6e-180 L AAA domain
JHKNLHEE_02013 5.3e-86
JHKNLHEE_02014 9.7e-283 3.6.4.12 J DnaB-like helicase C terminal domain
JHKNLHEE_02015 4.5e-224 L DNA primase activity
JHKNLHEE_02016 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
JHKNLHEE_02017 0.0 S Bacterial DNA polymerase III alpha subunit
JHKNLHEE_02018 2.7e-113 DR0488 S protein conserved in bacteria
JHKNLHEE_02023 1.6e-85 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
JHKNLHEE_02024 8.7e-90 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
JHKNLHEE_02026 5.7e-146 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
JHKNLHEE_02031 3.3e-13
JHKNLHEE_02041 3.3e-135 S HNH endonuclease
JHKNLHEE_02043 1.5e-62 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
JHKNLHEE_02044 3.8e-178 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JHKNLHEE_02045 3.3e-172 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JHKNLHEE_02046 4.2e-133 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
JHKNLHEE_02047 3.1e-198 rsiX
JHKNLHEE_02048 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
JHKNLHEE_02049 0.0 resE 2.7.13.3 T Histidine kinase
JHKNLHEE_02050 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JHKNLHEE_02051 5.3e-212 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
JHKNLHEE_02052 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
JHKNLHEE_02053 3.6e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
JHKNLHEE_02054 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
JHKNLHEE_02055 1.9e-87 spmB S Spore maturation protein
JHKNLHEE_02056 3.5e-103 spmA S Spore maturation protein
JHKNLHEE_02057 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
JHKNLHEE_02058 4e-98 ypuI S Protein of unknown function (DUF3907)
JHKNLHEE_02059 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JHKNLHEE_02060 6.4e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JHKNLHEE_02061 3.9e-90 ypuF S Domain of unknown function (DUF309)
JHKNLHEE_02062 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JHKNLHEE_02063 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
JHKNLHEE_02064 1.9e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JHKNLHEE_02065 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
JHKNLHEE_02066 1.6e-202 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JHKNLHEE_02067 7.8e-55 ypuD
JHKNLHEE_02068 8e-94 sipT 3.4.21.89 U Belongs to the peptidase S26 family
JHKNLHEE_02070 6.6e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
JHKNLHEE_02071 1.4e-08 S SNARE associated Golgi protein
JHKNLHEE_02073 4.7e-09 eaeH M Domain of Unknown Function (DUF1259)
JHKNLHEE_02075 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JHKNLHEE_02076 3.6e-149 ypuA S Secreted protein
JHKNLHEE_02077 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
JHKNLHEE_02078 1.7e-271 spoVAF EG Stage V sporulation protein AF
JHKNLHEE_02079 1.4e-110 spoVAEA S stage V sporulation protein
JHKNLHEE_02080 2.2e-57 spoVAEB S stage V sporulation protein
JHKNLHEE_02081 9e-192 spoVAD I Stage V sporulation protein AD
JHKNLHEE_02082 2.3e-78 spoVAC S stage V sporulation protein AC
JHKNLHEE_02083 1e-67 spoVAB S Stage V sporulation protein AB
JHKNLHEE_02084 9.6e-112 spoVAA S Stage V sporulation protein AA
JHKNLHEE_02085 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JHKNLHEE_02086 5.1e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
JHKNLHEE_02087 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
JHKNLHEE_02088 2.4e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
JHKNLHEE_02089 3.8e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JHKNLHEE_02090 1.1e-230 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
JHKNLHEE_02091 2.6e-166 xerD L recombinase XerD
JHKNLHEE_02092 1.4e-36 S Protein of unknown function (DUF4227)
JHKNLHEE_02093 2.4e-80 fur P Belongs to the Fur family
JHKNLHEE_02094 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
JHKNLHEE_02095 2.2e-31 yqkK
JHKNLHEE_02096 5.5e-242 mleA 1.1.1.38 C malic enzyme
JHKNLHEE_02097 3.1e-235 mleN C Na H antiporter
JHKNLHEE_02098 1.9e-267 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
JHKNLHEE_02099 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
JHKNLHEE_02100 1.3e-57 ansR K Transcriptional regulator
JHKNLHEE_02101 3.4e-219 yqxK 3.6.4.12 L DNA helicase
JHKNLHEE_02102 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
JHKNLHEE_02104 1.6e-166 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
JHKNLHEE_02105 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
JHKNLHEE_02106 0.0 ylaA
JHKNLHEE_02107 6.6e-41 ylaB
JHKNLHEE_02108 1.1e-87 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
JHKNLHEE_02109 2e-11 sigC S Putative zinc-finger
JHKNLHEE_02110 2.6e-37 ylaE
JHKNLHEE_02111 8.2e-22 S Family of unknown function (DUF5325)
JHKNLHEE_02112 0.0 typA T GTP-binding protein TypA
JHKNLHEE_02113 4.2e-47 ylaH S YlaH-like protein
JHKNLHEE_02114 2.5e-32 ylaI S protein conserved in bacteria
JHKNLHEE_02115 4.4e-88 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
JHKNLHEE_02116 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
JHKNLHEE_02117 1e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JHKNLHEE_02118 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
JHKNLHEE_02119 8.7e-44 ylaN S Belongs to the UPF0358 family
JHKNLHEE_02120 3.6e-211 ftsW D Belongs to the SEDS family
JHKNLHEE_02121 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JHKNLHEE_02122 2.2e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
JHKNLHEE_02123 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
JHKNLHEE_02124 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
JHKNLHEE_02125 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JHKNLHEE_02126 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
JHKNLHEE_02127 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
JHKNLHEE_02128 7e-164 ctaG S cytochrome c oxidase
JHKNLHEE_02129 7.7e-61 ylbA S YugN-like family
JHKNLHEE_02130 2.6e-74 ylbB T COG0517 FOG CBS domain
JHKNLHEE_02131 4.3e-200 ylbC S protein with SCP PR1 domains
JHKNLHEE_02132 4.1e-63 ylbD S Putative coat protein
JHKNLHEE_02133 6.7e-37 ylbE S YlbE-like protein
JHKNLHEE_02134 1.8e-75 ylbF S Belongs to the UPF0342 family
JHKNLHEE_02135 3.7e-38 ylbG S UPF0298 protein
JHKNLHEE_02136 2.5e-95 rsmD 2.1.1.171 L Methyltransferase
JHKNLHEE_02137 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JHKNLHEE_02138 7.2e-220 ylbJ S Sporulation integral membrane protein YlbJ
JHKNLHEE_02139 6.4e-137 ylbK S esterase of the alpha-beta hydrolase superfamily
JHKNLHEE_02140 2.6e-186 ylbL T Belongs to the peptidase S16 family
JHKNLHEE_02141 2.8e-235 ylbM S Belongs to the UPF0348 family
JHKNLHEE_02143 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
JHKNLHEE_02144 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
JHKNLHEE_02145 3.4e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
JHKNLHEE_02146 1.5e-88 ylbP K n-acetyltransferase
JHKNLHEE_02147 5.7e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JHKNLHEE_02148 1e-306 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
JHKNLHEE_02149 2.9e-78 mraZ K Belongs to the MraZ family
JHKNLHEE_02150 1.6e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
JHKNLHEE_02151 3.7e-44 ftsL D Essential cell division protein
JHKNLHEE_02152 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
JHKNLHEE_02153 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
JHKNLHEE_02154 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JHKNLHEE_02155 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JHKNLHEE_02156 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JHKNLHEE_02157 5.7e-186 spoVE D Belongs to the SEDS family
JHKNLHEE_02158 9.7e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JHKNLHEE_02159 5.3e-167 murB 1.3.1.98 M cell wall formation
JHKNLHEE_02160 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
JHKNLHEE_02161 5.4e-103 ylxW S protein conserved in bacteria
JHKNLHEE_02162 8.2e-117 ylxX S protein conserved in bacteria
JHKNLHEE_02163 1.4e-57 sbp S small basic protein
JHKNLHEE_02164 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
JHKNLHEE_02165 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JHKNLHEE_02166 0.0 bpr O COG1404 Subtilisin-like serine proteases
JHKNLHEE_02168 3.6e-171 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
JHKNLHEE_02169 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JHKNLHEE_02170 5.2e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JHKNLHEE_02171 3.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
JHKNLHEE_02172 4.5e-249 argE 3.5.1.16 E Acetylornithine deacetylase
JHKNLHEE_02173 2.4e-37 ylmC S sporulation protein
JHKNLHEE_02174 7e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
JHKNLHEE_02175 6.5e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JHKNLHEE_02176 5.1e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
JHKNLHEE_02177 1.1e-38 yggT S membrane
JHKNLHEE_02178 7.5e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
JHKNLHEE_02179 2.6e-67 divIVA D Cell division initiation protein
JHKNLHEE_02180 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JHKNLHEE_02181 1.3e-63 dksA T COG1734 DnaK suppressor protein
JHKNLHEE_02182 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JHKNLHEE_02183 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JHKNLHEE_02184 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JHKNLHEE_02185 1.5e-231 pyrP F Xanthine uracil
JHKNLHEE_02186 1.5e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
JHKNLHEE_02187 6.4e-251 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
JHKNLHEE_02188 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
JHKNLHEE_02189 0.0 carB 6.3.5.5 F Belongs to the CarB family
JHKNLHEE_02190 5.9e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
JHKNLHEE_02191 2.7e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
JHKNLHEE_02192 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
JHKNLHEE_02193 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JHKNLHEE_02194 7.7e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
JHKNLHEE_02195 9.2e-179 cysP P phosphate transporter
JHKNLHEE_02196 5e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
JHKNLHEE_02197 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
JHKNLHEE_02198 1.1e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
JHKNLHEE_02199 3.8e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
JHKNLHEE_02200 1.6e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
JHKNLHEE_02201 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
JHKNLHEE_02202 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
JHKNLHEE_02203 2.4e-156 yloC S stress-induced protein
JHKNLHEE_02204 1.5e-40 ylzA S Belongs to the UPF0296 family
JHKNLHEE_02205 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
JHKNLHEE_02206 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
JHKNLHEE_02207 1.4e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JHKNLHEE_02208 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JHKNLHEE_02209 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
JHKNLHEE_02210 6.5e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JHKNLHEE_02211 1.6e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JHKNLHEE_02212 1.4e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
JHKNLHEE_02213 1.6e-140 stp 3.1.3.16 T phosphatase
JHKNLHEE_02214 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
JHKNLHEE_02215 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
JHKNLHEE_02216 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
JHKNLHEE_02217 2e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
JHKNLHEE_02218 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
JHKNLHEE_02219 5.5e-59 asp S protein conserved in bacteria
JHKNLHEE_02220 1.6e-299 yloV S kinase related to dihydroxyacetone kinase
JHKNLHEE_02221 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
JHKNLHEE_02222 4.6e-155 sdaAA 4.3.1.17 E L-serine dehydratase
JHKNLHEE_02223 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JHKNLHEE_02224 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
JHKNLHEE_02225 8.1e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
JHKNLHEE_02226 1e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
JHKNLHEE_02227 6.1e-129 IQ reductase
JHKNLHEE_02228 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
JHKNLHEE_02229 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
JHKNLHEE_02230 0.0 smc D Required for chromosome condensation and partitioning
JHKNLHEE_02231 1.3e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
JHKNLHEE_02232 1.6e-124 S Phosphotransferase enzyme family
JHKNLHEE_02233 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JHKNLHEE_02234 3e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JHKNLHEE_02235 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
JHKNLHEE_02236 4.5e-36 ylqC S Belongs to the UPF0109 family
JHKNLHEE_02237 1.4e-60 ylqD S YlqD protein
JHKNLHEE_02238 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JHKNLHEE_02239 3.5e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
JHKNLHEE_02240 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
JHKNLHEE_02241 2.1e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JHKNLHEE_02242 2.9e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JHKNLHEE_02243 2.7e-289 ylqG
JHKNLHEE_02244 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
JHKNLHEE_02245 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
JHKNLHEE_02246 3.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JHKNLHEE_02247 8e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
JHKNLHEE_02248 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JHKNLHEE_02249 3.7e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JHKNLHEE_02250 2.5e-169 xerC L tyrosine recombinase XerC
JHKNLHEE_02251 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JHKNLHEE_02252 2.2e-249 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JHKNLHEE_02253 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JHKNLHEE_02255 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
JHKNLHEE_02256 1.3e-73 flgC N Belongs to the flagella basal body rod proteins family
JHKNLHEE_02257 1.9e-31 fliE N Flagellar hook-basal body
JHKNLHEE_02258 2.9e-253 fliF N The M ring may be actively involved in energy transduction
JHKNLHEE_02259 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
JHKNLHEE_02260 2.8e-105 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
JHKNLHEE_02261 7.2e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
JHKNLHEE_02262 4.2e-69 fliJ N Flagellar biosynthesis chaperone
JHKNLHEE_02263 3.8e-36 ylxF S MgtE intracellular N domain
JHKNLHEE_02264 2.3e-220 fliK N Flagellar hook-length control protein
JHKNLHEE_02265 1.7e-72 flgD N Flagellar basal body rod modification protein
JHKNLHEE_02266 2.2e-137 flgG N Flagellar basal body rod
JHKNLHEE_02267 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
JHKNLHEE_02268 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
JHKNLHEE_02269 1.5e-182 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JHKNLHEE_02270 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
JHKNLHEE_02271 1.6e-96 fliZ N Flagellar biosynthesis protein, FliO
JHKNLHEE_02272 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
JHKNLHEE_02273 6.4e-36 fliQ N Role in flagellar biosynthesis
JHKNLHEE_02274 3.6e-132 fliR N Flagellar biosynthetic protein FliR
JHKNLHEE_02275 2e-189 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JHKNLHEE_02276 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JHKNLHEE_02277 1.2e-200 flhF N Flagellar biosynthesis regulator FlhF
JHKNLHEE_02278 4.1e-156 flhG D Belongs to the ParA family
JHKNLHEE_02279 7.5e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
JHKNLHEE_02280 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
JHKNLHEE_02281 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
JHKNLHEE_02282 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
JHKNLHEE_02283 4.3e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
JHKNLHEE_02284 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JHKNLHEE_02285 3.1e-76 ylxL
JHKNLHEE_02286 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
JHKNLHEE_02287 8.2e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JHKNLHEE_02288 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
JHKNLHEE_02289 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
JHKNLHEE_02290 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JHKNLHEE_02291 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
JHKNLHEE_02292 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
JHKNLHEE_02293 7.7e-233 rasP M zinc metalloprotease
JHKNLHEE_02294 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
JHKNLHEE_02295 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JHKNLHEE_02296 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
JHKNLHEE_02297 1.1e-203 nusA K Participates in both transcription termination and antitermination
JHKNLHEE_02298 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
JHKNLHEE_02299 3.1e-47 ylxQ J ribosomal protein
JHKNLHEE_02300 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JHKNLHEE_02301 5e-44 ylxP S protein conserved in bacteria
JHKNLHEE_02302 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JHKNLHEE_02303 4.7e-171 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JHKNLHEE_02304 2.3e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
JHKNLHEE_02305 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JHKNLHEE_02306 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
JHKNLHEE_02307 6.8e-181 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
JHKNLHEE_02308 4.4e-233 pepR S Belongs to the peptidase M16 family
JHKNLHEE_02309 2.6e-42 ymxH S YlmC YmxH family
JHKNLHEE_02310 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
JHKNLHEE_02311 1.4e-107 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
JHKNLHEE_02312 3.2e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JHKNLHEE_02313 1.1e-220 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
JHKNLHEE_02314 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JHKNLHEE_02315 5.6e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JHKNLHEE_02316 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
JHKNLHEE_02317 4.4e-32 S YlzJ-like protein
JHKNLHEE_02318 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
JHKNLHEE_02319 1.4e-133 ymfC K Transcriptional regulator
JHKNLHEE_02320 3.8e-205 ymfD EGP Major facilitator Superfamily
JHKNLHEE_02321 2.3e-232 ymfF S Peptidase M16
JHKNLHEE_02322 1.9e-239 ymfH S zinc protease
JHKNLHEE_02323 7.8e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
JHKNLHEE_02324 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
JHKNLHEE_02325 2.7e-143 ymfK S Protein of unknown function (DUF3388)
JHKNLHEE_02326 2.1e-115 ymfM S protein conserved in bacteria
JHKNLHEE_02327 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JHKNLHEE_02328 2.8e-235 cinA 3.5.1.42 S Belongs to the CinA family
JHKNLHEE_02329 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JHKNLHEE_02330 4.4e-214 pbpX V Beta-lactamase
JHKNLHEE_02331 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
JHKNLHEE_02332 1.9e-152 ymdB S protein conserved in bacteria
JHKNLHEE_02333 1.2e-36 spoVS S Stage V sporulation protein S
JHKNLHEE_02334 2.8e-196 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
JHKNLHEE_02335 7.2e-217 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
JHKNLHEE_02336 6.5e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JHKNLHEE_02337 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
JHKNLHEE_02338 2.2e-88 cotE S Spore coat protein
JHKNLHEE_02339 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JHKNLHEE_02340 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JHKNLHEE_02341 2.2e-68 S Regulatory protein YrvL
JHKNLHEE_02342 1.1e-95 ymcC S Membrane
JHKNLHEE_02343 1.1e-102 pksA K Transcriptional regulator
JHKNLHEE_02344 4.4e-61 ymzB
JHKNLHEE_02345 5.8e-160 ymaE S Metallo-beta-lactamase superfamily
JHKNLHEE_02346 3e-96 aprX O Belongs to the peptidase S8 family
JHKNLHEE_02347 1e-119 aprX O Belongs to the peptidase S8 family
JHKNLHEE_02348 2.1e-126 ymaC S Replication protein
JHKNLHEE_02349 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
JHKNLHEE_02350 6.2e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
JHKNLHEE_02351 4.9e-51 ebrA P Small Multidrug Resistance protein
JHKNLHEE_02353 2.1e-46 ymaF S YmaF family
JHKNLHEE_02354 3.5e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JHKNLHEE_02355 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
JHKNLHEE_02356 8.2e-23
JHKNLHEE_02357 4.5e-22 ymzA
JHKNLHEE_02358 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
JHKNLHEE_02359 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JHKNLHEE_02360 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JHKNLHEE_02361 1.7e-108 ymaB
JHKNLHEE_02362 2.8e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
JHKNLHEE_02363 2.4e-97 spoVK O stage V sporulation protein K
JHKNLHEE_02365 5.8e-81 yhbS S family acetyltransferase
JHKNLHEE_02366 1.9e-108 yokF 3.1.31.1 L RNA catabolic process
JHKNLHEE_02367 7.6e-65 G SMI1-KNR4 cell-wall
JHKNLHEE_02368 1.7e-172 yobL S Bacterial EndoU nuclease
JHKNLHEE_02369 8.2e-76 S SMI1-KNR4 cell-wall
JHKNLHEE_02370 1.8e-91 yokK S SMI1 / KNR4 family
JHKNLHEE_02371 6.8e-100 S aspartate phosphatase
JHKNLHEE_02375 8.4e-54 S YolD-like protein
JHKNLHEE_02376 1.5e-233 S impB/mucB/samB family C-terminal domain
JHKNLHEE_02378 0.0 V Peptidase C39 family
JHKNLHEE_02379 1.2e-70 CO cell redox homeostasis
JHKNLHEE_02380 2.9e-240 M COG0463 Glycosyltransferases involved in cell wall biogenesis
JHKNLHEE_02381 3.4e-74 O protein disulfide oxidoreductase activity
JHKNLHEE_02382 5.5e-40 S SPP1 phage holin
JHKNLHEE_02383 4.4e-32 bhlA S BhlA holin family
JHKNLHEE_02384 5.5e-75 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
JHKNLHEE_02385 1e-183 M Pectate lyase superfamily protein
JHKNLHEE_02386 2.2e-119
JHKNLHEE_02387 5.2e-292 S Pfam Transposase IS66
JHKNLHEE_02388 8.5e-86 S Phage tail protein
JHKNLHEE_02389 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
JHKNLHEE_02390 5.8e-110
JHKNLHEE_02392 2.2e-22
JHKNLHEE_02393 2.2e-190 xerH A Belongs to the 'phage' integrase family
JHKNLHEE_02394 2.3e-56
JHKNLHEE_02395 1.6e-53
JHKNLHEE_02396 1.3e-98 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
JHKNLHEE_02397 1.6e-07 S Phage uncharacterised protein (Phage_XkdX)
JHKNLHEE_02398 2.1e-08
JHKNLHEE_02399 1.5e-35 S Domain of unknown function (DUF2479)
JHKNLHEE_02400 1.2e-45
JHKNLHEE_02403 3.2e-59
JHKNLHEE_02404 1.3e-72
JHKNLHEE_02405 5.7e-78
JHKNLHEE_02406 9.1e-68
JHKNLHEE_02409 3.3e-70
JHKNLHEE_02411 1.6e-35
JHKNLHEE_02412 4e-18
JHKNLHEE_02413 9.6e-109
JHKNLHEE_02414 4.9e-17
JHKNLHEE_02418 2e-203 S Calcineurin-like phosphoesterase superfamily domain
JHKNLHEE_02420 1.9e-35 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
JHKNLHEE_02421 0.0
JHKNLHEE_02424 3.6e-235
JHKNLHEE_02426 1.6e-198 3.1.21.3 L Domain of unknown function (DUF4942)
JHKNLHEE_02431 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JHKNLHEE_02432 4.9e-79 yfiV K transcriptional
JHKNLHEE_02433 2.7e-280 yfiU EGP Major facilitator Superfamily
JHKNLHEE_02434 4.7e-99 yfiT S Belongs to the metal hydrolase YfiT family
JHKNLHEE_02435 2.4e-194 yfiS EGP Major facilitator Superfamily
JHKNLHEE_02436 5.4e-107 yfiR K Transcriptional regulator
JHKNLHEE_02437 3.8e-196 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
JHKNLHEE_02438 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
JHKNLHEE_02439 8.3e-99 padR K transcriptional
JHKNLHEE_02440 1e-207 V COG0842 ABC-type multidrug transport system, permease component
JHKNLHEE_02441 2.2e-213 V ABC-2 family transporter protein
JHKNLHEE_02442 3.2e-167 V ABC transporter, ATP-binding protein
JHKNLHEE_02443 1.8e-111 KT LuxR family transcriptional regulator
JHKNLHEE_02444 8.8e-194 yxjM T Histidine kinase
JHKNLHEE_02445 1.1e-161 yfiE 1.13.11.2 S glyoxalase
JHKNLHEE_02446 6.4e-64 mhqP S DoxX
JHKNLHEE_02447 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
JHKNLHEE_02448 2.4e-306 yfiB3 V ABC transporter
JHKNLHEE_02449 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JHKNLHEE_02450 1.6e-140 glvR K Helix-turn-helix domain, rpiR family
JHKNLHEE_02451 4.9e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
JHKNLHEE_02452 7.4e-44 yfjA S Belongs to the WXG100 family
JHKNLHEE_02453 6.2e-171 yfjB
JHKNLHEE_02454 2.7e-124 yfjC
JHKNLHEE_02455 1.1e-85 S Family of unknown function (DUF5381)
JHKNLHEE_02456 4e-56 yfjF S UPF0060 membrane protein
JHKNLHEE_02457 1.2e-25 sspH S Belongs to the SspH family
JHKNLHEE_02458 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
JHKNLHEE_02459 1.2e-252 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
JHKNLHEE_02460 2.8e-192 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
JHKNLHEE_02461 8.5e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
JHKNLHEE_02462 2.2e-190 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
JHKNLHEE_02463 2.3e-29 yfjL
JHKNLHEE_02464 1.9e-85 yfjM S Psort location Cytoplasmic, score
JHKNLHEE_02465 7.1e-186 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JHKNLHEE_02466 2e-43 S YfzA-like protein
JHKNLHEE_02467 5.3e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JHKNLHEE_02468 5.2e-164 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JHKNLHEE_02469 5e-184 corA P Mediates influx of magnesium ions
JHKNLHEE_02470 9.8e-147 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
JHKNLHEE_02471 4.9e-153 pdaA G deacetylase
JHKNLHEE_02472 1.1e-26 yfjT
JHKNLHEE_02473 5.4e-222 yfkA S YfkB-like domain
JHKNLHEE_02474 2.5e-147 yfkC M Mechanosensitive ion channel
JHKNLHEE_02475 9e-123
JHKNLHEE_02476 6.5e-66 yybH S SnoaL-like domain
JHKNLHEE_02477 4e-121 yybG S Pentapeptide repeat-containing protein
JHKNLHEE_02478 2e-214 ynfM EGP Major facilitator Superfamily
JHKNLHEE_02479 2.6e-163 yybE K Transcriptional regulator
JHKNLHEE_02480 1.4e-77 yjcF S Acetyltransferase (GNAT) domain
JHKNLHEE_02481 3.6e-74 yybC
JHKNLHEE_02482 1.6e-125 S Metallo-beta-lactamase superfamily
JHKNLHEE_02483 5.6e-77 yybA 2.3.1.57 K transcriptional
JHKNLHEE_02484 2.9e-70 yjcF S Acetyltransferase (GNAT) domain
JHKNLHEE_02485 6.9e-94 yyaS S Membrane
JHKNLHEE_02486 2.1e-91 yyaR K Acetyltransferase (GNAT) domain
JHKNLHEE_02487 1e-65 yyaQ S YjbR
JHKNLHEE_02488 6.1e-105 yyaP 1.5.1.3 H RibD C-terminal domain
JHKNLHEE_02489 7.1e-248 tetL EGP Major facilitator Superfamily
JHKNLHEE_02490 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
JHKNLHEE_02491 8e-168 yyaK S CAAX protease self-immunity
JHKNLHEE_02492 3.9e-243 EGP Major facilitator superfamily
JHKNLHEE_02493 9.3e-90 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
JHKNLHEE_02494 1.4e-65 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JHKNLHEE_02495 8.9e-178 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
JHKNLHEE_02496 1.2e-143 xth 3.1.11.2 L exodeoxyribonuclease III
JHKNLHEE_02497 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JHKNLHEE_02498 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
JHKNLHEE_02499 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
JHKNLHEE_02500 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
JHKNLHEE_02501 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JHKNLHEE_02502 2.3e-33 yyzM S protein conserved in bacteria
JHKNLHEE_02503 8.1e-177 yyaD S Membrane
JHKNLHEE_02504 1.6e-111 yyaC S Sporulation protein YyaC
JHKNLHEE_02505 2.1e-149 spo0J K Belongs to the ParB family
JHKNLHEE_02506 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
JHKNLHEE_02507 9.6e-74 S Bacterial PH domain
JHKNLHEE_02508 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
JHKNLHEE_02509 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
JHKNLHEE_02510 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
JHKNLHEE_02511 3.7e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JHKNLHEE_02512 5.5e-107 jag S single-stranded nucleic acid binding R3H
JHKNLHEE_02513 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JHKNLHEE_02514 6.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
JHKNLHEE_02515 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JHKNLHEE_02516 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
JHKNLHEE_02517 2.4e-33 yaaA S S4 domain
JHKNLHEE_02518 5.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JHKNLHEE_02519 1.8e-37 yaaB S Domain of unknown function (DUF370)
JHKNLHEE_02520 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JHKNLHEE_02521 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JHKNLHEE_02522 1.9e-169 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JHKNLHEE_02523 4.9e-76 ykzC S Acetyltransferase (GNAT) family
JHKNLHEE_02524 1.8e-150 suhB 3.1.3.25 G Inositol monophosphatase
JHKNLHEE_02525 7.1e-26 ykzI
JHKNLHEE_02526 2.1e-117 yktB S Belongs to the UPF0637 family
JHKNLHEE_02527 2e-42 yktA S Belongs to the UPF0223 family
JHKNLHEE_02528 1.3e-276 speA 4.1.1.19 E Arginine
JHKNLHEE_02529 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
JHKNLHEE_02530 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
JHKNLHEE_02531 2.4e-229 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
JHKNLHEE_02532 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
JHKNLHEE_02533 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
JHKNLHEE_02534 2e-115 recN L Putative cell-wall binding lipoprotein
JHKNLHEE_02536 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
JHKNLHEE_02537 5.5e-147 ykrA S hydrolases of the HAD superfamily
JHKNLHEE_02538 8.2e-31 ykzG S Belongs to the UPF0356 family
JHKNLHEE_02539 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JHKNLHEE_02540 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JHKNLHEE_02541 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
JHKNLHEE_02542 3.2e-155 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
JHKNLHEE_02543 1.3e-240 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
JHKNLHEE_02544 1.5e-43 abrB K of stationary sporulation gene expression
JHKNLHEE_02545 7.7e-183 mreB D Rod-share determining protein MreBH
JHKNLHEE_02546 1.1e-12 S Uncharacterized protein YkpC
JHKNLHEE_02547 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
JHKNLHEE_02548 2e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JHKNLHEE_02549 1.7e-309 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
JHKNLHEE_02550 1.1e-38 ykoA
JHKNLHEE_02551 2.4e-104 sipT 3.4.21.89 U Belongs to the peptidase S26 family
JHKNLHEE_02552 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
JHKNLHEE_02553 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
JHKNLHEE_02554 3.1e-136 fruR K Transcriptional regulator
JHKNLHEE_02555 8.1e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
JHKNLHEE_02556 7.2e-124 macB V ABC transporter, ATP-binding protein
JHKNLHEE_02557 4.3e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JHKNLHEE_02558 1e-117 yknW S Yip1 domain
JHKNLHEE_02559 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
JHKNLHEE_02560 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
JHKNLHEE_02561 8.3e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JHKNLHEE_02562 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
JHKNLHEE_02563 1.9e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
JHKNLHEE_02564 1.2e-244 moeA 2.10.1.1 H molybdopterin
JHKNLHEE_02565 1.4e-189 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
JHKNLHEE_02566 3.3e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
JHKNLHEE_02567 1.9e-143 yknT
JHKNLHEE_02568 5.5e-189 yfmJ S N-terminal domain of oxidoreductase
JHKNLHEE_02569 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
JHKNLHEE_02570 7.7e-164 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JHKNLHEE_02571 4.7e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JHKNLHEE_02572 2.3e-165 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
JHKNLHEE_02573 5e-24 S Protein of unknown function (DUF3212)
JHKNLHEE_02574 7.6e-58 yflT S Heat induced stress protein YflT
JHKNLHEE_02575 1.4e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
JHKNLHEE_02576 5.5e-235 yflS P Sodium:sulfate symporter transmembrane region
JHKNLHEE_02577 3.7e-288 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
JHKNLHEE_02578 1.3e-117 citT T response regulator
JHKNLHEE_02579 4.8e-179 yflP S Tripartite tricarboxylate transporter family receptor
JHKNLHEE_02580 3.2e-226 citM C Citrate transporter
JHKNLHEE_02581 1.8e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
JHKNLHEE_02582 3.3e-216 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
JHKNLHEE_02583 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
JHKNLHEE_02584 6e-34 yflK S protein conserved in bacteria
JHKNLHEE_02585 1.4e-56 yflK S protein conserved in bacteria
JHKNLHEE_02586 8.9e-18 yflJ S Protein of unknown function (DUF2639)
JHKNLHEE_02587 4.1e-19 yflI
JHKNLHEE_02588 2.1e-42 yflH S Protein of unknown function (DUF3243)
JHKNLHEE_02589 2.1e-137 map 3.4.11.18 E Methionine aminopeptidase
JHKNLHEE_02590 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
JHKNLHEE_02591 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
JHKNLHEE_02592 6e-67 yhdN S Domain of unknown function (DUF1992)
JHKNLHEE_02593 9.3e-28 agcS_1 E Sodium alanine symporter
JHKNLHEE_02594 7.6e-95 yfkQ EG Spore germination protein
JHKNLHEE_02595 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JHKNLHEE_02596 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
JHKNLHEE_02597 6.7e-133 treR K transcriptional
JHKNLHEE_02598 1.5e-123 yfkO C nitroreductase
JHKNLHEE_02599 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
JHKNLHEE_02600 1.1e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
JHKNLHEE_02601 6.8e-207 ydiM EGP Major facilitator Superfamily
JHKNLHEE_02602 1.3e-28 yfkK S Belongs to the UPF0435 family
JHKNLHEE_02603 7.4e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JHKNLHEE_02604 2.4e-50 yfkI S gas vesicle protein
JHKNLHEE_02605 1.3e-143 yihY S Belongs to the UPF0761 family
JHKNLHEE_02606 5e-08
JHKNLHEE_02607 1e-215 ycaD EGP COG0477 Permeases of the major facilitator superfamily
JHKNLHEE_02608 6.1e-183 cax P COG0387 Ca2 H antiporter
JHKNLHEE_02609 1.2e-146 yfkD S YfkD-like protein
JHKNLHEE_02610 1.8e-168 T His Kinase A (phospho-acceptor) domain
JHKNLHEE_02611 1.3e-122 T Transcriptional regulatory protein, C terminal
JHKNLHEE_02612 7.6e-180 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
JHKNLHEE_02613 1.2e-55
JHKNLHEE_02614 4.5e-203 ybcL EGP Major facilitator Superfamily
JHKNLHEE_02615 5.1e-50 ybzH K Helix-turn-helix domain
JHKNLHEE_02616 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
JHKNLHEE_02617 6.2e-45
JHKNLHEE_02618 1.2e-91 can 4.2.1.1 P carbonic anhydrase
JHKNLHEE_02619 0.0 ybcC S Belongs to the UPF0753 family
JHKNLHEE_02620 7e-273 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
JHKNLHEE_02621 1.5e-100 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JHKNLHEE_02622 9.8e-120 adaA 3.2.2.21 K Transcriptional regulator
JHKNLHEE_02623 7.1e-172 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JHKNLHEE_02624 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
JHKNLHEE_02625 7.9e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JHKNLHEE_02626 1.8e-222 ybbR S protein conserved in bacteria
JHKNLHEE_02627 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JHKNLHEE_02628 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
JHKNLHEE_02629 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
JHKNLHEE_02635 1.6e-76 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
JHKNLHEE_02636 2.2e-28 ybbJ J acetyltransferase
JHKNLHEE_02637 6.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JHKNLHEE_02638 5.1e-148 ybbH K transcriptional
JHKNLHEE_02639 1.1e-232 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JHKNLHEE_02640 2e-252 yfeW 3.4.16.4 V Belongs to the UPF0214 family
JHKNLHEE_02641 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
JHKNLHEE_02642 4.3e-236 ybbC 3.2.1.52 S protein conserved in bacteria
JHKNLHEE_02643 3.8e-306 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
JHKNLHEE_02644 8.3e-163 feuA P Iron-uptake system-binding protein
JHKNLHEE_02645 1.8e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JHKNLHEE_02646 8.7e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JHKNLHEE_02647 1.4e-141 ybbA S Putative esterase
JHKNLHEE_02648 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
JHKNLHEE_02649 6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
JHKNLHEE_02651 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
JHKNLHEE_02652 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
JHKNLHEE_02653 2.1e-126 ccdA O cytochrome c biogenesis protein
JHKNLHEE_02654 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
JHKNLHEE_02655 1.8e-28 yneF S UPF0154 protein
JHKNLHEE_02656 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
JHKNLHEE_02657 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JHKNLHEE_02658 1.3e-32 ynzC S UPF0291 protein
JHKNLHEE_02659 2.9e-111 yneB L resolvase
JHKNLHEE_02660 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
JHKNLHEE_02661 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JHKNLHEE_02662 5.8e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
JHKNLHEE_02663 5.8e-74 yndM S Protein of unknown function (DUF2512)
JHKNLHEE_02664 6.8e-136 yndL S Replication protein
JHKNLHEE_02666 1.5e-305 yndJ S YndJ-like protein
JHKNLHEE_02667 5.2e-113 yndH S Domain of unknown function (DUF4166)
JHKNLHEE_02668 3.8e-153 yndG S DoxX-like family
JHKNLHEE_02669 5.1e-180 gerLC S Spore germination protein
JHKNLHEE_02670 1.1e-59 gerAB U Spore germination
JHKNLHEE_02671 1.1e-122 gerAB U Spore germination
JHKNLHEE_02672 9e-284 gerAA EG Spore germination protein
JHKNLHEE_02675 2.6e-79 yndB S Activator of Hsp90 ATPase homolog 1-like protein
JHKNLHEE_02676 3.7e-51
JHKNLHEE_02677 7.9e-25 tatA U protein secretion
JHKNLHEE_02680 5.5e-127 S Domain of unknown function, YrpD
JHKNLHEE_02682 5.4e-32
JHKNLHEE_02683 1.9e-163 S Thymidylate synthase
JHKNLHEE_02686 5.2e-15
JHKNLHEE_02687 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
JHKNLHEE_02688 5.3e-83 yncE S Protein of unknown function (DUF2691)
JHKNLHEE_02689 2.7e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JHKNLHEE_02690 6.8e-254 iolT EGP Major facilitator Superfamily
JHKNLHEE_02691 1.7e-111 yokF 3.1.31.1 L RNA catabolic process
JHKNLHEE_02692 1.3e-290 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
JHKNLHEE_02693 2.4e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
JHKNLHEE_02694 3.1e-212 xylR GK ROK family
JHKNLHEE_02695 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
JHKNLHEE_02696 1.8e-254 xynT G MFS/sugar transport protein
JHKNLHEE_02697 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
JHKNLHEE_02698 4.4e-259 mcpC NT chemotaxis protein
JHKNLHEE_02699 2e-126 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JHKNLHEE_02700 1.4e-200 splB 4.1.99.14 L Spore photoproduct lyase
JHKNLHEE_02701 7.2e-39 splA S Transcriptional regulator
JHKNLHEE_02702 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JHKNLHEE_02703 2.1e-39 ptsH G phosphocarrier protein HPr
JHKNLHEE_02704 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JHKNLHEE_02705 7.6e-128 glcT K antiterminator
JHKNLHEE_02707 6.4e-179 ykvZ 5.1.1.1 K Transcriptional regulator
JHKNLHEE_02708 1.1e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
JHKNLHEE_02709 2.3e-09
JHKNLHEE_02710 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
JHKNLHEE_02711 1.6e-88 stoA CO thiol-disulfide
JHKNLHEE_02712 2.2e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JHKNLHEE_02713 4.8e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
JHKNLHEE_02714 2.8e-28
JHKNLHEE_02715 6e-25 ykvS S protein conserved in bacteria
JHKNLHEE_02716 2.8e-45 ykvR S Protein of unknown function (DUF3219)
JHKNLHEE_02717 2.4e-162 G Glycosyl hydrolases family 18
JHKNLHEE_02718 3.5e-35 3.5.1.104 M LysM domain
JHKNLHEE_02719 2.9e-215 ykvP 3.5.1.28 M Glycosyl transferases group 1
JHKNLHEE_02720 1.2e-132 IQ Enoyl-(Acyl carrier protein) reductase
JHKNLHEE_02721 2e-61 ykvN K Transcriptional regulator
JHKNLHEE_02722 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JHKNLHEE_02723 2.4e-138 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
JHKNLHEE_02724 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
JHKNLHEE_02725 6.2e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JHKNLHEE_02726 2.4e-179 ykvI S membrane
JHKNLHEE_02727 0.0 clpE O Belongs to the ClpA ClpB family
JHKNLHEE_02728 8.6e-137 motA N flagellar motor
JHKNLHEE_02729 1.5e-122 motB N Flagellar motor protein
JHKNLHEE_02730 1.3e-75 ykvE K transcriptional
JHKNLHEE_02731 2.4e-273 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
JHKNLHEE_02732 3.3e-113 tetR3 K Transcriptional regulator
JHKNLHEE_02733 1.9e-118 mepA V Multidrug transporter MatE
JHKNLHEE_02734 5.3e-70 mepA V Multidrug transporter MatE
JHKNLHEE_02735 8.6e-164 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
JHKNLHEE_02736 2.1e-111 yrkJ S membrane transporter protein
JHKNLHEE_02737 5.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
JHKNLHEE_02738 9.3e-206 yrkH P Rhodanese Homology Domain
JHKNLHEE_02739 4.2e-98 yrkF OP Belongs to the sulfur carrier protein TusA family
JHKNLHEE_02740 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
JHKNLHEE_02741 1e-38 yrkD S protein conserved in bacteria
JHKNLHEE_02742 8.6e-21
JHKNLHEE_02743 1.8e-104 yrkC G Cupin domain
JHKNLHEE_02744 3.1e-150 bltR K helix_turn_helix, mercury resistance
JHKNLHEE_02745 3.5e-211 blt EGP Major facilitator Superfamily
JHKNLHEE_02746 1.5e-82 bltD 2.3.1.57 K FR47-like protein
JHKNLHEE_02747 1.6e-233 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
JHKNLHEE_02748 3.9e-16 S YrzO-like protein
JHKNLHEE_02749 1.9e-170 yrdR EG EamA-like transporter family
JHKNLHEE_02750 6.6e-159 yrdQ K Transcriptional regulator
JHKNLHEE_02751 3.6e-196 trkA P Oxidoreductase
JHKNLHEE_02752 2.6e-153 czcD P COG1230 Co Zn Cd efflux system component
JHKNLHEE_02753 4.2e-65 yodA S tautomerase
JHKNLHEE_02754 5e-162 gltR K LysR substrate binding domain
JHKNLHEE_02755 1.1e-226 brnQ E Component of the transport system for branched-chain amino acids
JHKNLHEE_02756 5.6e-50 azlD E Branched-chain amino acid transport protein (AzlD)
JHKNLHEE_02757 2.2e-91 azlC E AzlC protein
JHKNLHEE_02758 1.1e-78 bkdR K helix_turn_helix ASNC type
JHKNLHEE_02759 2.6e-40 yrdF K ribonuclease inhibitor
JHKNLHEE_02760 1e-226 cypA C Cytochrome P450
JHKNLHEE_02761 1e-99 yrdC 3.5.1.19 Q Isochorismatase family
JHKNLHEE_02762 1.9e-57 S Protein of unknown function (DUF2568)
JHKNLHEE_02763 5.8e-95 rok K Repressor of ComK
JHKNLHEE_02764 6.3e-81 ykuV CO thiol-disulfide
JHKNLHEE_02765 4.3e-100 ykuU O Alkyl hydroperoxide reductase
JHKNLHEE_02766 2.6e-141 ykuT M Mechanosensitive ion channel
JHKNLHEE_02767 9e-37 ykuS S Belongs to the UPF0180 family
JHKNLHEE_02768 1.6e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
JHKNLHEE_02769 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
JHKNLHEE_02770 1.6e-76 fld C Flavodoxin
JHKNLHEE_02771 5.2e-175 ykuO
JHKNLHEE_02772 1.7e-84 fld C Flavodoxin domain
JHKNLHEE_02773 3.5e-168 ccpC K Transcriptional regulator
JHKNLHEE_02774 4.7e-76 ykuL S CBS domain
JHKNLHEE_02775 3.9e-27 ykzF S Antirepressor AbbA
JHKNLHEE_02776 4.4e-94 ykuK S Ribonuclease H-like
JHKNLHEE_02777 3.9e-37 ykuJ S protein conserved in bacteria
JHKNLHEE_02779 3.3e-233 ykuI T Diguanylate phosphodiesterase
JHKNLHEE_02781 3.2e-124 M Peptidoglycan-binding domain 1 protein
JHKNLHEE_02782 0.0 3.2.1.132 M Putative peptidoglycan binding domain
JHKNLHEE_02783 6.4e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JHKNLHEE_02784 1.6e-165 ykuE S Metallophosphoesterase
JHKNLHEE_02785 1.5e-86 ykuD S protein conserved in bacteria
JHKNLHEE_02786 4.8e-238 ykuC EGP Major facilitator Superfamily
JHKNLHEE_02787 1.7e-84 ykyB S YkyB-like protein
JHKNLHEE_02788 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
JHKNLHEE_02789 2.2e-15
JHKNLHEE_02790 3.7e-221 patA 2.6.1.1 E Aminotransferase
JHKNLHEE_02791 0.0 pilS 2.7.13.3 T Histidine kinase
JHKNLHEE_02792 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
JHKNLHEE_02793 8e-124 ykwD J protein with SCP PR1 domains
JHKNLHEE_02794 1.8e-98 yciC S GTPases (G3E family)
JHKNLHEE_02795 3.6e-112 yciC S GTPases (G3E family)
JHKNLHEE_02796 4.2e-101 yciB M ErfK YbiS YcfS YnhG
JHKNLHEE_02797 1.2e-171 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
JHKNLHEE_02798 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
JHKNLHEE_02799 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
JHKNLHEE_02800 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JHKNLHEE_02801 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JHKNLHEE_02802 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
JHKNLHEE_02803 1.5e-272 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
JHKNLHEE_02804 4e-192 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
JHKNLHEE_02805 8.5e-159 I alpha/beta hydrolase fold
JHKNLHEE_02806 6.5e-138 ycgR S permeases
JHKNLHEE_02807 4.8e-146 ycgQ S membrane
JHKNLHEE_02808 6.2e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
JHKNLHEE_02809 3.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JHKNLHEE_02810 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
JHKNLHEE_02811 5.1e-170 ycgM E Proline dehydrogenase
JHKNLHEE_02812 1.2e-143 ycgL S Predicted nucleotidyltransferase
JHKNLHEE_02813 9.4e-183 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
JHKNLHEE_02814 5.6e-175 oxyR3 K LysR substrate binding domain
JHKNLHEE_02815 1.4e-141 yafE Q ubiE/COQ5 methyltransferase family
JHKNLHEE_02816 3e-75 spo0M S COG4326 Sporulation control protein
JHKNLHEE_02817 1.2e-43 spo0M S COG4326 Sporulation control protein
JHKNLHEE_02818 1.2e-26
JHKNLHEE_02819 2.3e-130 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
JHKNLHEE_02820 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JHKNLHEE_02821 7.6e-263 ygaK C Berberine and berberine like
JHKNLHEE_02823 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
JHKNLHEE_02824 1.1e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
JHKNLHEE_02825 7.3e-170 ssuA M Sulfonate ABC transporter
JHKNLHEE_02826 4.2e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
JHKNLHEE_02827 2.6e-216 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
JHKNLHEE_02829 1.7e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JHKNLHEE_02830 1.3e-76 ygaO
JHKNLHEE_02831 4.4e-29 K Transcriptional regulator
JHKNLHEE_02833 3.3e-112 yhzB S B3/4 domain
JHKNLHEE_02834 6.6e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JHKNLHEE_02835 4.1e-175 yhbB S Putative amidase domain
JHKNLHEE_02836 9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
JHKNLHEE_02837 2.1e-109 yhbD K Protein of unknown function (DUF4004)
JHKNLHEE_02838 2.7e-13 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
JHKNLHEE_02839 4.2e-46 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
JHKNLHEE_02840 2.1e-70 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
JHKNLHEE_02841 0.0 prkA T Ser protein kinase
JHKNLHEE_02842 2.5e-225 yhbH S Belongs to the UPF0229 family
JHKNLHEE_02843 2.2e-76 yhbI K DNA-binding transcription factor activity
JHKNLHEE_02844 3.8e-87 yhbJ V COG1566 Multidrug resistance efflux pump
JHKNLHEE_02845 1.5e-270 yhcA EGP Major facilitator Superfamily
JHKNLHEE_02846 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
JHKNLHEE_02847 2.8e-37 yhcC
JHKNLHEE_02848 3.6e-52
JHKNLHEE_02849 2.5e-59 yhcF K Transcriptional regulator
JHKNLHEE_02850 8.8e-122 yhcG V ABC transporter, ATP-binding protein
JHKNLHEE_02851 7.2e-164 yhcH V ABC transporter, ATP-binding protein
JHKNLHEE_02852 2.5e-164 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
JHKNLHEE_02853 1e-30 cspB K Cold-shock protein
JHKNLHEE_02854 3.1e-150 metQ M Belongs to the nlpA lipoprotein family
JHKNLHEE_02855 8.4e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
JHKNLHEE_02856 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
JHKNLHEE_02857 4.9e-41 yhcM
JHKNLHEE_02858 2.1e-61 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
JHKNLHEE_02859 7e-160 yhcP
JHKNLHEE_02860 1.6e-96 yhcQ M Spore coat protein
JHKNLHEE_02861 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
JHKNLHEE_02862 2.1e-103 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
JHKNLHEE_02863 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JHKNLHEE_02864 9.3e-68 yhcU S Family of unknown function (DUF5365)
JHKNLHEE_02865 3.8e-67 yhcV S COG0517 FOG CBS domain
JHKNLHEE_02866 1e-119 yhcW 5.4.2.6 S hydrolase
JHKNLHEE_02867 4.6e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
JHKNLHEE_02868 5.4e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JHKNLHEE_02869 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
JHKNLHEE_02870 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
JHKNLHEE_02871 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JHKNLHEE_02872 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JHKNLHEE_02873 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
JHKNLHEE_02874 1.4e-212 yhcY 2.7.13.3 T Histidine kinase
JHKNLHEE_02875 6.5e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JHKNLHEE_02876 4.2e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
JHKNLHEE_02877 3.6e-38 yhdB S YhdB-like protein
JHKNLHEE_02878 4.8e-54 yhdC S Protein of unknown function (DUF3889)
JHKNLHEE_02879 1e-183 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
JHKNLHEE_02880 1e-75 nsrR K Transcriptional regulator
JHKNLHEE_02881 9.6e-238 ygxB M Conserved TM helix
JHKNLHEE_02882 6.8e-262 ycgB S Stage V sporulation protein R
JHKNLHEE_02883 3.5e-255 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
JHKNLHEE_02884 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
JHKNLHEE_02885 3.8e-162 citR K Transcriptional regulator
JHKNLHEE_02886 2e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
JHKNLHEE_02887 6e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JHKNLHEE_02888 7.6e-250 yhdG E amino acid
JHKNLHEE_02889 1.5e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
JHKNLHEE_02890 2.1e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JHKNLHEE_02891 5.9e-76 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JHKNLHEE_02892 8.1e-45 yhdK S Sigma-M inhibitor protein
JHKNLHEE_02893 6.6e-201 yhdL S Sigma factor regulator N-terminal
JHKNLHEE_02894 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
JHKNLHEE_02895 1.4e-189 yhdN C Aldo keto reductase
JHKNLHEE_02896 6.7e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
JHKNLHEE_02897 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
JHKNLHEE_02898 9.1e-74 cueR K transcriptional
JHKNLHEE_02899 2e-222 yhdR 2.6.1.1 E Aminotransferase
JHKNLHEE_02900 4.6e-239 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
JHKNLHEE_02901 9.3e-43 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JHKNLHEE_02902 4.3e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JHKNLHEE_02903 2.3e-133 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
JHKNLHEE_02905 5.6e-203 yhdY M Mechanosensitive ion channel
JHKNLHEE_02906 2.6e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
JHKNLHEE_02907 3.9e-148 yheN G deacetylase
JHKNLHEE_02908 1.8e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
JHKNLHEE_02909 2.1e-228 nhaC C Na H antiporter
JHKNLHEE_02910 1.7e-83 nhaX T Belongs to the universal stress protein A family
JHKNLHEE_02911 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
JHKNLHEE_02912 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
JHKNLHEE_02913 2.6e-109 yheG GM NAD(P)H-binding
JHKNLHEE_02914 6.3e-28 sspB S spore protein
JHKNLHEE_02915 1.3e-36 yheE S Family of unknown function (DUF5342)
JHKNLHEE_02916 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
JHKNLHEE_02917 4.3e-216 yheC HJ YheC/D like ATP-grasp
JHKNLHEE_02918 6.3e-202 yheB S Belongs to the UPF0754 family
JHKNLHEE_02919 9.5e-48 yheA S Belongs to the UPF0342 family
JHKNLHEE_02920 5.3e-104 yhaZ L DNA alkylation repair enzyme
JHKNLHEE_02921 4.4e-74 yhaZ L DNA alkylation repair enzyme
JHKNLHEE_02922 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
JHKNLHEE_02923 1.8e-292 hemZ H coproporphyrinogen III oxidase
JHKNLHEE_02924 8.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
JHKNLHEE_02925 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
JHKNLHEE_02927 4.6e-132 yhaR 5.3.3.18 I enoyl-CoA hydratase
JHKNLHEE_02928 1.1e-26 S YhzD-like protein
JHKNLHEE_02929 1.2e-166 yhaQ S ABC transporter, ATP-binding protein
JHKNLHEE_02930 7.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
JHKNLHEE_02931 2e-222 yhaO L DNA repair exonuclease
JHKNLHEE_02932 0.0 yhaN L AAA domain
JHKNLHEE_02933 5.8e-177 yhaM L Shows a 3'-5' exoribonuclease activity
JHKNLHEE_02934 1.6e-21 yhaL S Sporulation protein YhaL
JHKNLHEE_02935 1e-119 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
JHKNLHEE_02936 1.1e-89 yhaK S Putative zincin peptidase
JHKNLHEE_02937 1.3e-54 yhaI S Protein of unknown function (DUF1878)
JHKNLHEE_02938 1e-113 hpr K Negative regulator of protease production and sporulation
JHKNLHEE_02939 7e-39 yhaH S YtxH-like protein
JHKNLHEE_02940 3.6e-80 trpP S Tryptophan transporter TrpP
JHKNLHEE_02941 8.4e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JHKNLHEE_02942 1.1e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
JHKNLHEE_02943 4.6e-137 ecsA V transporter (ATP-binding protein)
JHKNLHEE_02944 1.6e-214 ecsB U ABC transporter
JHKNLHEE_02945 1.4e-114 ecsC S EcsC protein family
JHKNLHEE_02946 2.8e-229 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
JHKNLHEE_02947 8.7e-246 yhfA C membrane
JHKNLHEE_02948 1.9e-34 1.15.1.2 C Rubrerythrin
JHKNLHEE_02949 8.4e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
JHKNLHEE_02950 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JHKNLHEE_02951 4.1e-203 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JHKNLHEE_02952 3.6e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
JHKNLHEE_02953 4.1e-267 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JHKNLHEE_02954 4.6e-100 yhgD K Transcriptional regulator
JHKNLHEE_02955 1.9e-216 yhgE S YhgE Pip N-terminal domain protein
JHKNLHEE_02956 3.3e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JHKNLHEE_02957 1.1e-136 yhfC S Putative membrane peptidase family (DUF2324)
JHKNLHEE_02958 1.3e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
JHKNLHEE_02959 3.7e-72 3.4.13.21 S ASCH
JHKNLHEE_02960 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
JHKNLHEE_02961 3.4e-140 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
JHKNLHEE_02962 4.9e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
JHKNLHEE_02963 2.9e-111 yhfK GM NmrA-like family
JHKNLHEE_02964 3.1e-300 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
JHKNLHEE_02965 1.4e-63 yhfM
JHKNLHEE_02966 2.3e-240 yhfN 3.4.24.84 O Peptidase M48
JHKNLHEE_02967 1.2e-203 aprE 3.4.21.62 O Belongs to the peptidase S8 family
JHKNLHEE_02968 6.2e-76 VY92_01935 K acetyltransferase
JHKNLHEE_02969 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
JHKNLHEE_02970 3.8e-155 yfmC M Periplasmic binding protein
JHKNLHEE_02971 7.1e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
JHKNLHEE_02972 5.5e-195 vraB 2.3.1.9 I Belongs to the thiolase family
JHKNLHEE_02973 9e-270 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
JHKNLHEE_02974 2.5e-90 bioY S BioY family
JHKNLHEE_02975 1.4e-181 hemAT NT chemotaxis protein
JHKNLHEE_02976 7.4e-97 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
JHKNLHEE_02977 1.6e-188 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
JHKNLHEE_02978 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JHKNLHEE_02979 1.3e-32 yhzC S IDEAL
JHKNLHEE_02980 4.2e-109 comK K Competence transcription factor
JHKNLHEE_02981 1.4e-167 IQ Enoyl-(Acyl carrier protein) reductase
JHKNLHEE_02982 2.8e-39 yhjA S Excalibur calcium-binding domain
JHKNLHEE_02983 1.4e-265 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JHKNLHEE_02984 6.9e-27 yhjC S Protein of unknown function (DUF3311)
JHKNLHEE_02985 6.7e-60 yhjD
JHKNLHEE_02986 9.1e-110 yhjE S SNARE associated Golgi protein
JHKNLHEE_02987 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
JHKNLHEE_02988 1.6e-282 yhjG CH FAD binding domain
JHKNLHEE_02989 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
JHKNLHEE_02990 2e-214 glcP G Major Facilitator Superfamily
JHKNLHEE_02991 4.6e-199 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
JHKNLHEE_02992 9e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
JHKNLHEE_02993 5.9e-79 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
JHKNLHEE_02994 5.4e-116 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
JHKNLHEE_02995 2e-91 yhjM 5.1.1.1 K Transcriptional regulator
JHKNLHEE_02996 2.5e-65 yhjM 5.1.1.1 K Transcriptional regulator
JHKNLHEE_02997 1.9e-201 abrB S membrane
JHKNLHEE_02998 6.4e-213 EGP Transmembrane secretion effector
JHKNLHEE_02999 0.0 S Sugar transport-related sRNA regulator N-term
JHKNLHEE_03000 6.4e-78 yhjR S Rubrerythrin
JHKNLHEE_03001 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
JHKNLHEE_03002 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
JHKNLHEE_03003 9.1e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
JHKNLHEE_03004 0.0 sbcC L COG0419 ATPase involved in DNA repair
JHKNLHEE_03005 3.1e-47 yisB V COG1403 Restriction endonuclease
JHKNLHEE_03006 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
JHKNLHEE_03007 3e-66 gerPE S Spore germination protein GerPE
JHKNLHEE_03008 6.3e-24 gerPD S Spore germination protein
JHKNLHEE_03009 5.3e-54 gerPC S Spore germination protein
JHKNLHEE_03010 4e-34 gerPB S cell differentiation
JHKNLHEE_03011 1.9e-33 gerPA S Spore germination protein
JHKNLHEE_03012 1.5e-22 yisI S Spo0E like sporulation regulatory protein
JHKNLHEE_03013 8.4e-78 cotH M Spore Coat
JHKNLHEE_03014 1.5e-53 cotH M Spore Coat
JHKNLHEE_03015 2.1e-171 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
JHKNLHEE_03016 3e-57 yisL S UPF0344 protein
JHKNLHEE_03017 0.0 wprA O Belongs to the peptidase S8 family
JHKNLHEE_03018 1.3e-102 yisN S Protein of unknown function (DUF2777)
JHKNLHEE_03019 0.0 asnO 6.3.5.4 E Asparagine synthase
JHKNLHEE_03020 1.5e-117 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
JHKNLHEE_03021 5.2e-243 yisQ V Mate efflux family protein
JHKNLHEE_03022 1.6e-160 yisR K Transcriptional regulator
JHKNLHEE_03023 1.4e-181 purR K helix_turn _helix lactose operon repressor
JHKNLHEE_03024 5.4e-179 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
JHKNLHEE_03025 7e-92 yisT S DinB family
JHKNLHEE_03026 1.2e-106 argO S Lysine exporter protein LysE YggA
JHKNLHEE_03027 7.6e-277 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JHKNLHEE_03028 2e-35 mcbG S Pentapeptide repeats (9 copies)
JHKNLHEE_03029 1.2e-154 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
JHKNLHEE_03030 1e-110 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
JHKNLHEE_03031 5.1e-164 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
JHKNLHEE_03032 5.4e-52 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
JHKNLHEE_03033 1.5e-57 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
JHKNLHEE_03034 5.5e-63 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
JHKNLHEE_03035 2.5e-121 comB 3.1.3.71 H Belongs to the ComB family
JHKNLHEE_03036 3.5e-140 yitD 4.4.1.19 S synthase
JHKNLHEE_03037 1.9e-107 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
JHKNLHEE_03038 4.4e-42 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
JHKNLHEE_03039 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
JHKNLHEE_03040 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
JHKNLHEE_03041 1.2e-30 csbA S protein conserved in bacteria
JHKNLHEE_03042 0.0 yvkC 2.7.9.2 GT Phosphotransferase
JHKNLHEE_03043 7e-101 yvkB K Transcriptional regulator
JHKNLHEE_03044 7.9e-228 yvkA EGP Major facilitator Superfamily
JHKNLHEE_03045 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JHKNLHEE_03046 5.3e-56 swrA S Swarming motility protein
JHKNLHEE_03047 2e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
JHKNLHEE_03048 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
JHKNLHEE_03049 1.6e-123 ftsE D cell division ATP-binding protein FtsE
JHKNLHEE_03050 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
JHKNLHEE_03051 7.1e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
JHKNLHEE_03052 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JHKNLHEE_03053 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
JHKNLHEE_03054 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JHKNLHEE_03055 4.6e-51
JHKNLHEE_03056 1.9e-08 fliT S bacterial-type flagellum organization
JHKNLHEE_03057 1.9e-68 fliS N flagellar protein FliS
JHKNLHEE_03058 7.7e-248 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JHKNLHEE_03059 1.2e-52 flaG N flagellar protein FlaG
JHKNLHEE_03060 1.5e-109 istB2 L IstB-like ATP binding protein
JHKNLHEE_03064 3.3e-59 yusQ S Tautomerase enzyme
JHKNLHEE_03065 4.2e-292 yusP P Major facilitator superfamily
JHKNLHEE_03066 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
JHKNLHEE_03067 5.4e-53 yusN M Coat F domain
JHKNLHEE_03068 5.1e-40
JHKNLHEE_03069 1.9e-164 fadM E Proline dehydrogenase
JHKNLHEE_03070 8.1e-09 S YuzL-like protein
JHKNLHEE_03071 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
JHKNLHEE_03072 7.9e-216 fadA 2.3.1.16 I Belongs to the thiolase family
JHKNLHEE_03073 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
JHKNLHEE_03074 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
JHKNLHEE_03075 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
JHKNLHEE_03076 1.1e-39 yusG S Protein of unknown function (DUF2553)
JHKNLHEE_03077 1.1e-72 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
JHKNLHEE_03078 6.2e-54 traF CO Thioredoxin
JHKNLHEE_03079 3.2e-56 yusD S SCP-2 sterol transfer family
JHKNLHEE_03080 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JHKNLHEE_03081 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
JHKNLHEE_03082 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
JHKNLHEE_03083 2.3e-47 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JHKNLHEE_03084 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
JHKNLHEE_03085 3.5e-244 sufD O assembly protein SufD
JHKNLHEE_03086 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JHKNLHEE_03087 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
JHKNLHEE_03088 3.5e-271 sufB O FeS cluster assembly
JHKNLHEE_03089 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
JHKNLHEE_03090 1.5e-292 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JHKNLHEE_03091 8.2e-232 ytfP S HI0933-like protein
JHKNLHEE_03092 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
JHKNLHEE_03093 3.1e-26 yteV S Sporulation protein Cse60
JHKNLHEE_03094 3.4e-115 yteU S Integral membrane protein
JHKNLHEE_03095 2.5e-255 yteT S Oxidoreductase family, C-terminal alpha/beta domain
JHKNLHEE_03096 5.1e-72 yteS G transport
JHKNLHEE_03097 1.7e-220 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
JHKNLHEE_03098 2.2e-171 lplB G COG4209 ABC-type polysaccharide transport system, permease component
JHKNLHEE_03099 0.0 ytdP K Transcriptional regulator
JHKNLHEE_03100 2.4e-286 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
JHKNLHEE_03101 1.3e-149 ytcP G COG0395 ABC-type sugar transport system, permease component
JHKNLHEE_03102 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
JHKNLHEE_03103 2.4e-220 bioI 1.14.14.46 C Cytochrome P450
JHKNLHEE_03104 2.1e-188 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JHKNLHEE_03105 1.7e-125 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JHKNLHEE_03106 2.8e-213 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
JHKNLHEE_03107 5.6e-258 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
JHKNLHEE_03108 5.5e-149 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
JHKNLHEE_03109 9.1e-12 yqkE S Protein of unknown function (DUF3886)
JHKNLHEE_03110 4.6e-171 yqkD S COG1073 Hydrolases of the alpha beta superfamily
JHKNLHEE_03111 9.4e-39 yqkC S Protein of unknown function (DUF2552)
JHKNLHEE_03112 2.8e-54 yqkB S Belongs to the HesB IscA family
JHKNLHEE_03113 1.2e-191 yqkA K GrpB protein
JHKNLHEE_03114 6.8e-59 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
JHKNLHEE_03115 3.6e-87 yqjY K acetyltransferase
JHKNLHEE_03116 1.7e-49 S YolD-like protein
JHKNLHEE_03117 9.2e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JHKNLHEE_03119 1.3e-221 yqjV G Major Facilitator Superfamily
JHKNLHEE_03121 8.8e-71 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JHKNLHEE_03122 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
JHKNLHEE_03123 9.3e-261 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
JHKNLHEE_03124 4.6e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
JHKNLHEE_03125 7.7e-177 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
JHKNLHEE_03126 6.4e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JHKNLHEE_03127 0.0 rocB E arginine degradation protein
JHKNLHEE_03128 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
JHKNLHEE_03129 1.4e-144 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
JHKNLHEE_03130 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
JHKNLHEE_03131 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
JHKNLHEE_03132 2.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JHKNLHEE_03134 3.4e-183 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JHKNLHEE_03135 1.7e-35 O Glutaredoxin
JHKNLHEE_03136 1.1e-09
JHKNLHEE_03137 3.6e-73 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
JHKNLHEE_03142 4.7e-162 S Thymidylate synthase
JHKNLHEE_03143 2e-30 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JHKNLHEE_03145 7e-36
JHKNLHEE_03147 6.8e-25 sspB S spore protein
JHKNLHEE_03155 1e-94 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
JHKNLHEE_03157 5.3e-245 cisA2 L Recombinase
JHKNLHEE_03158 8.7e-69 spoVK O stage V sporulation protein K
JHKNLHEE_03159 2.1e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JHKNLHEE_03160 9.7e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
JHKNLHEE_03161 1.1e-68 glnR K transcriptional
JHKNLHEE_03162 1e-259 glnA 6.3.1.2 E glutamine synthetase
JHKNLHEE_03163 3.7e-74 L Belongs to the 'phage' integrase family
JHKNLHEE_03165 5e-23 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
JHKNLHEE_03166 2.6e-39 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
JHKNLHEE_03167 2.4e-195 yetN S Protein of unknown function (DUF3900)
JHKNLHEE_03168 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
JHKNLHEE_03169 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
JHKNLHEE_03170 1e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
JHKNLHEE_03171 1.9e-172 yfnG 4.2.1.45 M dehydratase
JHKNLHEE_03172 7.1e-180 yfnF M Nucleotide-diphospho-sugar transferase
JHKNLHEE_03173 2.7e-224 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
JHKNLHEE_03174 1e-189 yfnD M Nucleotide-diphospho-sugar transferase
JHKNLHEE_03175 4.6e-206 fsr P COG0477 Permeases of the major facilitator superfamily
JHKNLHEE_03176 1.8e-130 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
JHKNLHEE_03177 4.2e-240 yfnA E amino acid
JHKNLHEE_03178 8.2e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
JHKNLHEE_03179 1e-111 yfmS NT chemotaxis protein
JHKNLHEE_03180 6.7e-167 ygxA S Nucleotidyltransferase-like
JHKNLHEE_03181 9.5e-56 ygzB S UPF0295 protein
JHKNLHEE_03182 4e-80 perR P Belongs to the Fur family
JHKNLHEE_03183 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
JHKNLHEE_03184 4e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
JHKNLHEE_03185 8.7e-180 ygaE S Membrane
JHKNLHEE_03186 1.8e-301 ygaD V ABC transporter
JHKNLHEE_03187 1.3e-104 ygaC J Belongs to the UPF0374 family
JHKNLHEE_03188 4.9e-48 ygaB S YgaB-like protein
JHKNLHEE_03189 5.3e-08 sspE S Small, acid-soluble spore protein, gamma-type
JHKNLHEE_03190 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JHKNLHEE_03191 6.9e-36 yfhS
JHKNLHEE_03192 2.5e-210 mutY L A G-specific
JHKNLHEE_03193 2.1e-185 yfhP S membrane-bound metal-dependent
JHKNLHEE_03194 0.0 yfhO S Bacterial membrane protein YfhO
JHKNLHEE_03195 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
JHKNLHEE_03196 1.3e-170 yfhM S Alpha beta hydrolase
JHKNLHEE_03197 3.9e-50 yfhL S SdpI/YhfL protein family
JHKNLHEE_03198 9.2e-92 batE T Bacterial SH3 domain homologues
JHKNLHEE_03199 1.3e-63 hxlR K transcriptional
JHKNLHEE_03200 8.9e-105 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
JHKNLHEE_03201 1.9e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
JHKNLHEE_03202 1.4e-176 tlpC 2.7.13.3 NT chemotaxis protein
JHKNLHEE_03203 5.6e-69 nucA M Deoxyribonuclease NucA/NucB
JHKNLHEE_03204 8.5e-69 nin S Competence protein J (ComJ)
JHKNLHEE_03205 1.3e-50 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JHKNLHEE_03206 3.7e-122 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JHKNLHEE_03207 4.8e-87 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JHKNLHEE_03208 7.8e-52 yckD S Protein of unknown function (DUF2680)
JHKNLHEE_03209 5.8e-74 yckC S membrane
JHKNLHEE_03211 4.1e-129 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
JHKNLHEE_03212 1e-114 yecS P COG0765 ABC-type amino acid transport system, permease component
JHKNLHEE_03213 4.9e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
JHKNLHEE_03214 3.6e-21 ywtC
JHKNLHEE_03215 1.8e-217 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
JHKNLHEE_03216 8.6e-70 pgsC S biosynthesis protein
JHKNLHEE_03217 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
JHKNLHEE_03218 2.1e-177 rbsR K transcriptional
JHKNLHEE_03219 1.5e-158 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JHKNLHEE_03220 2e-62 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
JHKNLHEE_03221 2.3e-273 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
JHKNLHEE_03222 9.3e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
JHKNLHEE_03223 7e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
JHKNLHEE_03224 9.6e-92 batE T Sh3 type 3 domain protein
JHKNLHEE_03225 7.2e-37 ywsA S Protein of unknown function (DUF3892)
JHKNLHEE_03226 4.4e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
JHKNLHEE_03227 4.8e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
JHKNLHEE_03228 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
JHKNLHEE_03229 1.1e-169 alsR K LysR substrate binding domain
JHKNLHEE_03230 2.9e-163 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JHKNLHEE_03231 4.1e-124 ywrJ
JHKNLHEE_03232 8.8e-77 cotB
JHKNLHEE_03233 4.8e-23 cotB
JHKNLHEE_03234 4e-206 cotH M Spore Coat
JHKNLHEE_03235 1.1e-12
JHKNLHEE_03236 8.4e-108 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JHKNLHEE_03237 2.5e-53 S Domain of unknown function (DUF4181)
JHKNLHEE_03238 9.7e-302 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
JHKNLHEE_03239 8e-82 ywrC K Transcriptional regulator
JHKNLHEE_03240 1.2e-103 ywrB P Chromate transporter
JHKNLHEE_03241 9.9e-89 ywrA P COG2059 Chromate transport protein ChrA
JHKNLHEE_03242 3e-117 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
JHKNLHEE_03243 3.9e-25
JHKNLHEE_03244 1.6e-81 ywqJ S Pre-toxin TG
JHKNLHEE_03245 5.2e-17
JHKNLHEE_03246 7.9e-43
JHKNLHEE_03247 7.4e-213 ywqJ L nucleic acid phosphodiester bond hydrolysis
JHKNLHEE_03248 2e-37 ywqI S Family of unknown function (DUF5344)
JHKNLHEE_03249 1e-19 S Domain of unknown function (DUF5082)
JHKNLHEE_03250 5.7e-85 ywqG S Domain of unknown function (DUF1963)
JHKNLHEE_03251 9.5e-30 ywqG S Domain of unknown function (DUF1963)
JHKNLHEE_03252 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
JHKNLHEE_03253 1.6e-236 ktrB P Potassium
JHKNLHEE_03254 1e-38 yiaA S yiaA/B two helix domain
JHKNLHEE_03255 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
JHKNLHEE_03256 3.5e-272 yubD P Major Facilitator Superfamily
JHKNLHEE_03257 1.3e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
JHKNLHEE_03259 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
JHKNLHEE_03260 1.3e-194 yubA S transporter activity
JHKNLHEE_03261 9.7e-183 ygjR S Oxidoreductase
JHKNLHEE_03262 1.1e-252 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
JHKNLHEE_03263 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
JHKNLHEE_03264 1.6e-249 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
JHKNLHEE_03265 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
JHKNLHEE_03266 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
JHKNLHEE_03267 7.3e-238 mcpA NT chemotaxis protein
JHKNLHEE_03268 5.5e-294 mcpA NT chemotaxis protein
JHKNLHEE_03269 2.8e-41 mcpA NT chemotaxis protein
JHKNLHEE_03270 9.1e-35 mcpA NT chemotaxis protein
JHKNLHEE_03271 1.5e-113 mcpA NT chemotaxis protein
JHKNLHEE_03272 6.1e-41 mcpA NT chemotaxis protein
JHKNLHEE_03273 6e-169 mcpA NT chemotaxis protein
JHKNLHEE_03274 4.9e-131 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
JHKNLHEE_03275 3.9e-35
JHKNLHEE_03276 2.2e-72 yugU S Uncharacterised protein family UPF0047
JHKNLHEE_03277 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
JHKNLHEE_03278 8.4e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
JHKNLHEE_03279 1.4e-116 yugP S Zn-dependent protease
JHKNLHEE_03280 3.7e-36
JHKNLHEE_03281 1.2e-52 mstX S Membrane-integrating protein Mistic
JHKNLHEE_03282 3.1e-181 yugO P COG1226 Kef-type K transport systems
JHKNLHEE_03283 1.4e-71 yugN S YugN-like family
JHKNLHEE_03285 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
JHKNLHEE_03286 2.8e-229 yugK C Dehydrogenase
JHKNLHEE_03287 2e-227 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
JHKNLHEE_03288 1.1e-34 yuzA S Domain of unknown function (DUF378)
JHKNLHEE_03289 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
JHKNLHEE_03290 2.1e-199 yugH 2.6.1.1 E Aminotransferase
JHKNLHEE_03291 1.6e-85 alaR K Transcriptional regulator
JHKNLHEE_03292 1.4e-155 yugF I Hydrolase
JHKNLHEE_03293 1.3e-38 yugE S Domain of unknown function (DUF1871)
JHKNLHEE_03294 1.9e-186 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
JHKNLHEE_03295 2.8e-28 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
JHKNLHEE_03296 4.6e-233 T PhoQ Sensor
JHKNLHEE_03297 2.2e-69 kapB G Kinase associated protein B
JHKNLHEE_03298 4.2e-115 kapD L the KinA pathway to sporulation
JHKNLHEE_03300 4.2e-184 yuxJ EGP Major facilitator Superfamily
JHKNLHEE_03301 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
JHKNLHEE_03302 1.8e-74 yuxK S protein conserved in bacteria
JHKNLHEE_03303 6.3e-78 yufK S Family of unknown function (DUF5366)
JHKNLHEE_03304 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
JHKNLHEE_03305 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
JHKNLHEE_03306 1.7e-196 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
JHKNLHEE_03307 1e-271 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
JHKNLHEE_03308 1.4e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
JHKNLHEE_03309 1.1e-167 yufQ S Belongs to the binding-protein-dependent transport system permease family
JHKNLHEE_03310 3.7e-233 maeN C COG3493 Na citrate symporter
JHKNLHEE_03311 3.2e-14
JHKNLHEE_03312 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
JHKNLHEE_03313 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
JHKNLHEE_03314 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
JHKNLHEE_03315 7.1e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
JHKNLHEE_03316 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
JHKNLHEE_03317 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
JHKNLHEE_03318 3.3e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
JHKNLHEE_03319 1.8e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
JHKNLHEE_03320 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JHKNLHEE_03321 0.0 comP 2.7.13.3 T Histidine kinase
JHKNLHEE_03323 3.1e-149 comQ H Polyprenyl synthetase
JHKNLHEE_03325 1.1e-22 yuzC
JHKNLHEE_03326 3.8e-229 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
JHKNLHEE_03327 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JHKNLHEE_03328 1.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
JHKNLHEE_03329 1.8e-66 yueI S Protein of unknown function (DUF1694)
JHKNLHEE_03330 7.4e-39 yueH S YueH-like protein
JHKNLHEE_03331 2.5e-30 yueG S Spore germination protein gerPA/gerPF
JHKNLHEE_03332 3.2e-190 yueF S transporter activity
JHKNLHEE_03333 5.2e-71 S Protein of unknown function (DUF2283)
JHKNLHEE_03334 1.1e-23 S Protein of unknown function (DUF2642)
JHKNLHEE_03335 1.1e-95 yueE S phosphohydrolase
JHKNLHEE_03336 9.2e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JHKNLHEE_03337 6.6e-65 yueC S Family of unknown function (DUF5383)
JHKNLHEE_03338 0.0 esaA S type VII secretion protein EsaA
JHKNLHEE_03339 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
JHKNLHEE_03340 5.2e-211 essB S WXG100 protein secretion system (Wss), protein YukC
JHKNLHEE_03341 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
JHKNLHEE_03342 2.8e-45 esxA S Belongs to the WXG100 family
JHKNLHEE_03343 2.8e-227 yukF QT Transcriptional regulator
JHKNLHEE_03344 8.8e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
JHKNLHEE_03345 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
JHKNLHEE_03346 8.5e-36 mbtH S MbtH-like protein
JHKNLHEE_03347 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JHKNLHEE_03348 9.3e-175 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
JHKNLHEE_03349 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
JHKNLHEE_03350 4.7e-224 entC 5.4.4.2 HQ Isochorismate synthase
JHKNLHEE_03351 8.1e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JHKNLHEE_03352 1.5e-166 besA S Putative esterase
JHKNLHEE_03353 2.1e-119 yuiH S Oxidoreductase molybdopterin binding domain
JHKNLHEE_03354 7.4e-93 bioY S Biotin biosynthesis protein
JHKNLHEE_03355 8.1e-209 yuiF S antiporter
JHKNLHEE_03356 1e-279 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JHKNLHEE_03357 1.2e-77 yuiD S protein conserved in bacteria
JHKNLHEE_03358 6.8e-116 yuiC S protein conserved in bacteria
JHKNLHEE_03359 3.2e-26 yuiB S Putative membrane protein
JHKNLHEE_03360 3.2e-236 yumB 1.6.99.3 C NADH dehydrogenase
JHKNLHEE_03361 1.7e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
JHKNLHEE_03363 1.8e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
JHKNLHEE_03364 6.1e-114 paiB K Putative FMN-binding domain
JHKNLHEE_03365 4.3e-49 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JHKNLHEE_03366 3.7e-63 erpA S Belongs to the HesB IscA family
JHKNLHEE_03367 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JHKNLHEE_03368 1.7e-197 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JHKNLHEE_03369 3.2e-39 yuzB S Belongs to the UPF0349 family
JHKNLHEE_03370 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
JHKNLHEE_03371 1.1e-55 yuzD S protein conserved in bacteria
JHKNLHEE_03372 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
JHKNLHEE_03373 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
JHKNLHEE_03374 2.8e-171 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
JHKNLHEE_03375 5.2e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JHKNLHEE_03376 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
JHKNLHEE_03377 8.5e-198 yutH S Spore coat protein
JHKNLHEE_03378 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
JHKNLHEE_03379 3.2e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
JHKNLHEE_03380 1e-75 yutE S Protein of unknown function DUF86
JHKNLHEE_03381 1.1e-46 yutD S protein conserved in bacteria
JHKNLHEE_03382 6.7e-66 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
JHKNLHEE_03383 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JHKNLHEE_03384 1.3e-195 lytH M Peptidase, M23
JHKNLHEE_03385 3.2e-133 yunB S Sporulation protein YunB (Spo_YunB)
JHKNLHEE_03386 1.1e-47 yunC S Domain of unknown function (DUF1805)
JHKNLHEE_03387 5.1e-262 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
JHKNLHEE_03388 1.3e-140 yunE S membrane transporter protein
JHKNLHEE_03389 7.3e-171 yunF S Protein of unknown function DUF72
JHKNLHEE_03390 6.7e-62 yunG
JHKNLHEE_03391 7.3e-258 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
JHKNLHEE_03392 3.2e-300 pucR QT COG2508 Regulator of polyketide synthase expression
JHKNLHEE_03393 3.9e-235 pbuX F Permease family
JHKNLHEE_03394 1.4e-96 pbuX F xanthine
JHKNLHEE_03395 9.7e-113 pbuX F xanthine
JHKNLHEE_03396 1.6e-277 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
JHKNLHEE_03397 1e-54 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
JHKNLHEE_03398 4e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
JHKNLHEE_03399 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
JHKNLHEE_03400 4.3e-147 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
JHKNLHEE_03401 1.2e-109 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
JHKNLHEE_03402 5e-187 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JHKNLHEE_03403 8.7e-237 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
JHKNLHEE_03404 2e-233 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
JHKNLHEE_03405 7.7e-168 bsn L Ribonuclease
JHKNLHEE_03406 2.9e-204 msmX P Belongs to the ABC transporter superfamily
JHKNLHEE_03407 7.3e-135 yurK K UTRA
JHKNLHEE_03408 1.1e-148 yurL 2.7.1.218 G pfkB family carbohydrate kinase
JHKNLHEE_03409 4.7e-238 yurO G COG1653 ABC-type sugar transport system, periplasmic component
JHKNLHEE_03410 3.7e-182 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
JHKNLHEE_03411 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
JHKNLHEE_03412 2.2e-207 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
JHKNLHEE_03414 1e-41
JHKNLHEE_03415 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
JHKNLHEE_03416 7.9e-32 yaaL S Protein of unknown function (DUF2508)
JHKNLHEE_03417 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JHKNLHEE_03418 1.2e-36 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JHKNLHEE_03419 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JHKNLHEE_03420 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
JHKNLHEE_03421 1.4e-95 yaaI Q COG1335 Amidases related to nicotinamidase
JHKNLHEE_03422 2.1e-209 yaaH M Glycoside Hydrolase Family
JHKNLHEE_03423 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
JHKNLHEE_03424 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
JHKNLHEE_03425 1.3e-09
JHKNLHEE_03426 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JHKNLHEE_03427 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JHKNLHEE_03428 2.8e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JHKNLHEE_03429 7.5e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
JHKNLHEE_03430 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
JHKNLHEE_03431 1.1e-178 yaaC S YaaC-like Protein
JHKNLHEE_03432 6.7e-292 ydaB IQ acyl-CoA ligase
JHKNLHEE_03433 0.0 mtlR K transcriptional regulator, MtlR
JHKNLHEE_03434 9.8e-174 ydhF S Oxidoreductase
JHKNLHEE_03435 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
JHKNLHEE_03436 1.4e-49 yczJ S biosynthesis
JHKNLHEE_03438 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
JHKNLHEE_03439 3.9e-131 kipR K Transcriptional regulator
JHKNLHEE_03440 1.4e-184 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
JHKNLHEE_03441 3.6e-134 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
JHKNLHEE_03442 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
JHKNLHEE_03443 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
JHKNLHEE_03444 3.6e-140 ycsF S Belongs to the UPF0271 (lamB) family
JHKNLHEE_03445 5.2e-136 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
JHKNLHEE_03447 8.3e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JHKNLHEE_03448 3e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
JHKNLHEE_03449 2.2e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
JHKNLHEE_03450 2e-116 ywqC M biosynthesis protein
JHKNLHEE_03451 1.2e-17
JHKNLHEE_03452 7.8e-307 ywqB S SWIM zinc finger
JHKNLHEE_03453 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
JHKNLHEE_03454 1.8e-156 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
JHKNLHEE_03455 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
JHKNLHEE_03456 2.2e-57 ssbB L Single-stranded DNA-binding protein
JHKNLHEE_03457 3.8e-66 ywpG
JHKNLHEE_03458 1.1e-66 ywpF S YwpF-like protein
JHKNLHEE_03459 2.4e-29 KLT Protein tyrosine kinase
JHKNLHEE_03460 4.3e-11 S YolD-like protein
JHKNLHEE_03461 1.9e-36
JHKNLHEE_03462 9e-19
JHKNLHEE_03464 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
JHKNLHEE_03465 5.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
JHKNLHEE_03467 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
JHKNLHEE_03468 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
JHKNLHEE_03469 5.6e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
JHKNLHEE_03470 5.9e-49 yjdF S Protein of unknown function (DUF2992)
JHKNLHEE_03471 3.9e-139 KLT Protein tyrosine kinase
JHKNLHEE_03472 7.7e-152 ybdN
JHKNLHEE_03473 2.4e-212 ybdO S Domain of unknown function (DUF4885)
JHKNLHEE_03474 8.4e-257 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
JHKNLHEE_03475 3.1e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
JHKNLHEE_03476 4.9e-30 ybxH S Family of unknown function (DUF5370)
JHKNLHEE_03477 7.5e-149 ybxI 3.5.2.6 V beta-lactamase
JHKNLHEE_03478 6.6e-245 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
JHKNLHEE_03479 4.9e-41 ybyB
JHKNLHEE_03480 3e-290 ybeC E amino acid
JHKNLHEE_03481 1.3e-44 yfhJ S WVELL protein
JHKNLHEE_03482 6.2e-20 sspK S reproduction
JHKNLHEE_03483 5.6e-209 yfhI EGP Major facilitator Superfamily
JHKNLHEE_03485 9.7e-52 yfhH S Protein of unknown function (DUF1811)
JHKNLHEE_03486 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
JHKNLHEE_03487 6e-171 yfhF S nucleoside-diphosphate sugar epimerase
JHKNLHEE_03489 2.1e-25 yfhD S YfhD-like protein
JHKNLHEE_03490 3.9e-107 yfhC C nitroreductase
JHKNLHEE_03491 5.3e-164 yfhB 5.3.3.17 S PhzF family
JHKNLHEE_03492 4.4e-170 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JHKNLHEE_03493 9.9e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JHKNLHEE_03494 3.9e-176 yfiY P ABC transporter substrate-binding protein
JHKNLHEE_03495 2.2e-91 yuaB
JHKNLHEE_03496 5.5e-95 yuaC K Belongs to the GbsR family
JHKNLHEE_03497 1.2e-280 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
JHKNLHEE_03498 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
JHKNLHEE_03499 7.4e-106 yuaD
JHKNLHEE_03500 3.9e-84 yuaE S DinB superfamily
JHKNLHEE_03501 4.2e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
JHKNLHEE_03502 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
JHKNLHEE_03503 3.4e-94 M1-753 M FR47-like protein
JHKNLHEE_03504 5.7e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
JHKNLHEE_03505 1.2e-249 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JHKNLHEE_03506 1.1e-89 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JHKNLHEE_03507 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
JHKNLHEE_03508 5.7e-74 yfmQ S Uncharacterised protein from bacillus cereus group
JHKNLHEE_03509 1.4e-69 yfmP K transcriptional
JHKNLHEE_03510 1.9e-209 yfmO EGP Major facilitator Superfamily
JHKNLHEE_03511 7.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
JHKNLHEE_03512 1.9e-198 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
JHKNLHEE_03513 2.2e-97 ydaC Q Methyltransferase domain
JHKNLHEE_03514 2e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JHKNLHEE_03515 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
JHKNLHEE_03516 3.6e-102 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
JHKNLHEE_03517 2e-76 ydaG 1.4.3.5 S general stress protein
JHKNLHEE_03518 1e-137 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
JHKNLHEE_03519 3.3e-46 ydzA EGP Major facilitator Superfamily
JHKNLHEE_03520 2.5e-74 lrpC K Transcriptional regulator
JHKNLHEE_03521 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JHKNLHEE_03522 5.9e-91 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
JHKNLHEE_03524 6.8e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JHKNLHEE_03525 4.2e-29 S Domain of unknown function (DUF4177)
JHKNLHEE_03526 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
JHKNLHEE_03527 2.8e-174 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
JHKNLHEE_03529 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
JHKNLHEE_03530 1.8e-81 S Protein of unknown function (DUF2690)
JHKNLHEE_03531 1.7e-18 yjfB S Putative motility protein
JHKNLHEE_03532 9.8e-166 yjfC O Predicted Zn-dependent protease (DUF2268)
JHKNLHEE_03533 3.9e-44 T PhoQ Sensor
JHKNLHEE_03534 2.9e-102 yjgB S Domain of unknown function (DUF4309)
JHKNLHEE_03535 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
JHKNLHEE_03536 8.3e-72 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
JHKNLHEE_03537 1.6e-94 yjgD S Protein of unknown function (DUF1641)
JHKNLHEE_03540 3.9e-68 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
JHKNLHEE_03542 1.6e-219 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
JHKNLHEE_03543 1.1e-217 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
JHKNLHEE_03544 3.1e-29
JHKNLHEE_03545 1.3e-140 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
JHKNLHEE_03546 9.5e-122 ybbM S transport system, permease component
JHKNLHEE_03547 6.4e-134 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
JHKNLHEE_03548 1.1e-175 yjlA EG Putative multidrug resistance efflux transporter
JHKNLHEE_03549 1.1e-89 yjlB S Cupin domain
JHKNLHEE_03550 7.1e-66 yjlC S Protein of unknown function (DUF1641)
JHKNLHEE_03551 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
JHKNLHEE_03552 6.7e-278 uxaC 5.3.1.12 G glucuronate isomerase
JHKNLHEE_03553 1.3e-246 yjmB G symporter YjmB
JHKNLHEE_03554 7.1e-189 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
JHKNLHEE_03555 3.1e-192 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
JHKNLHEE_03556 5.4e-211 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
JHKNLHEE_03558 7e-130 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JHKNLHEE_03559 1e-224 exuT G Sugar (and other) transporter
JHKNLHEE_03560 1.4e-181 exuR K transcriptional
JHKNLHEE_03561 1.9e-280 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
JHKNLHEE_03562 3.2e-286 uxaA 4.2.1.7, 4.4.1.24 G Altronate
JHKNLHEE_03563 1.3e-129 MA20_18170 S membrane transporter protein
JHKNLHEE_03564 2.3e-78 yjoA S DinB family
JHKNLHEE_03565 8.8e-245 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
JHKNLHEE_03566 1e-212 S response regulator aspartate phosphatase
JHKNLHEE_03568 1.2e-39 S YCII-related domain
JHKNLHEE_03569 1.6e-158 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
JHKNLHEE_03570 1.8e-60 yjqA S Bacterial PH domain
JHKNLHEE_03571 2.3e-110 yjqB S Pfam:DUF867
JHKNLHEE_03572 1.3e-159 ydbD P Catalase
JHKNLHEE_03573 6.6e-110 xkdA E IrrE N-terminal-like domain
JHKNLHEE_03574 9.2e-56 xre K Helix-turn-helix XRE-family like proteins
JHKNLHEE_03576 5.5e-152 xkdC L Bacterial dnaA protein
JHKNLHEE_03579 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
JHKNLHEE_03580 3.5e-83 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
JHKNLHEE_03581 4.1e-139 xtmA L phage terminase small subunit
JHKNLHEE_03582 2.2e-251 xtmB S phage terminase, large subunit
JHKNLHEE_03583 2.4e-18 yqbA S portal protein
JHKNLHEE_03584 1e-168 yqbA S portal protein
JHKNLHEE_03585 1.6e-48 yqbA S portal protein
JHKNLHEE_03586 3.5e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
JHKNLHEE_03587 1.7e-168 xkdG S Phage capsid family
JHKNLHEE_03588 9.6e-62 yqbG S Protein of unknown function (DUF3199)
JHKNLHEE_03589 4.3e-64 yqbH S Domain of unknown function (DUF3599)
JHKNLHEE_03590 4.9e-87 xkdI S Bacteriophage HK97-gp10, putative tail-component
JHKNLHEE_03591 1.2e-76 xkdJ
JHKNLHEE_03592 2.5e-256 xkdK S Phage tail sheath C-terminal domain
JHKNLHEE_03593 6.1e-76 xkdM S Phage tail tube protein
JHKNLHEE_03594 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
JHKNLHEE_03595 0.0 xkdO L Transglycosylase SLT domain
JHKNLHEE_03596 8.9e-116 xkdP S Lysin motif
JHKNLHEE_03597 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
JHKNLHEE_03598 2.1e-39 xkdR S Protein of unknown function (DUF2577)
JHKNLHEE_03599 9.6e-71 xkdS S Protein of unknown function (DUF2634)
JHKNLHEE_03600 6.2e-123 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
JHKNLHEE_03601 1.4e-57 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
JHKNLHEE_03602 4e-104 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
JHKNLHEE_03603 6.7e-41
JHKNLHEE_03604 0.0
JHKNLHEE_03605 4.6e-52 xkdW S XkdW protein
JHKNLHEE_03606 9.3e-22 xkdX
JHKNLHEE_03607 5.8e-152 xepA
JHKNLHEE_03608 1.8e-38 xhlA S Haemolysin XhlA
JHKNLHEE_03609 9.3e-40 xhlB S SPP1 phage holin
JHKNLHEE_03610 5e-162 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
JHKNLHEE_03611 6.7e-23 spoIISB S Stage II sporulation protein SB
JHKNLHEE_03612 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
JHKNLHEE_03613 7.6e-175 pit P phosphate transporter
JHKNLHEE_03614 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
JHKNLHEE_03615 9.8e-239 steT E amino acid
JHKNLHEE_03616 1.8e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
JHKNLHEE_03617 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JHKNLHEE_03618 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
JHKNLHEE_03619 3.2e-213 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JHKNLHEE_03620 2.6e-133 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
JHKNLHEE_03621 5.1e-153 dppA E D-aminopeptidase
JHKNLHEE_03622 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JHKNLHEE_03623 3.6e-174 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JHKNLHEE_03624 1.3e-187 dppD P Belongs to the ABC transporter superfamily
JHKNLHEE_03625 0.0 dppE E ABC transporter substrate-binding protein
JHKNLHEE_03627 2.9e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
JHKNLHEE_03628 1.7e-199 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
JHKNLHEE_03629 2.2e-165 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
JHKNLHEE_03630 1.5e-186 ykfD E Belongs to the ABC transporter superfamily
JHKNLHEE_03631 5.3e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
JHKNLHEE_03632 1.7e-159 ykgA E Amidinotransferase
JHKNLHEE_03633 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
JHKNLHEE_03634 2.5e-225 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JHKNLHEE_03636 1.9e-127 ykjA S Protein of unknown function (DUF421)
JHKNLHEE_03637 9.7e-97 ykkA S Protein of unknown function (DUF664)
JHKNLHEE_03638 1.5e-97 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
JHKNLHEE_03639 1.1e-53 ykkC P Multidrug resistance protein
JHKNLHEE_03640 9.1e-50 ykkD P Multidrug resistance protein
JHKNLHEE_03641 5.6e-169 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
JHKNLHEE_03642 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JHKNLHEE_03643 2.1e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JHKNLHEE_03644 6.3e-70 ohrA O Organic hydroperoxide resistance protein
JHKNLHEE_03645 1.7e-73 ohrR K COG1846 Transcriptional regulators
JHKNLHEE_03646 8.4e-72 ohrB O Organic hydroperoxide resistance protein
JHKNLHEE_03647 5.5e-83 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
JHKNLHEE_03648 2.2e-100 5.4.2.11 G Belongs to the phosphoglycerate mutase family
JHKNLHEE_03649 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JHKNLHEE_03650 5e-176 isp O Belongs to the peptidase S8 family
JHKNLHEE_03651 1.8e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
JHKNLHEE_03652 5.3e-136 ykoC P Cobalt transport protein
JHKNLHEE_03653 7.2e-308 P ABC transporter, ATP-binding protein
JHKNLHEE_03654 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
JHKNLHEE_03655 5.1e-110 ykoF S YKOF-related Family
JHKNLHEE_03656 1.8e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JHKNLHEE_03657 5.7e-159 ykoH 2.7.13.3 T Histidine kinase
JHKNLHEE_03658 3e-67 ykoH 2.7.13.3 T Histidine kinase
JHKNLHEE_03659 3.1e-69 ykoI S Peptidase propeptide and YPEB domain
JHKNLHEE_03660 9.2e-84 ykoJ S Peptidase propeptide and YPEB domain
JHKNLHEE_03663 2.2e-222 mgtE P Acts as a magnesium transporter
JHKNLHEE_03664 1.4e-53 tnrA K transcriptional
JHKNLHEE_03665 5.9e-18
JHKNLHEE_03666 3.4e-25 ykoL
JHKNLHEE_03667 1.3e-81 mhqR K transcriptional
JHKNLHEE_03668 1.4e-217 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
JHKNLHEE_03669 6.3e-97 ykoP G polysaccharide deacetylase
JHKNLHEE_03670 6e-154 ykoQ S Calcineurin-like phosphoesterase superfamily domain
JHKNLHEE_03671 0.0 ykoS
JHKNLHEE_03672 2.1e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
JHKNLHEE_03673 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
JHKNLHEE_03674 1.4e-159 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
JHKNLHEE_03675 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
JHKNLHEE_03676 1.7e-108 ykoX S membrane-associated protein
JHKNLHEE_03677 4.6e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
JHKNLHEE_03678 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JHKNLHEE_03679 1.5e-105 rsgI S Anti-sigma factor N-terminus
JHKNLHEE_03680 1.9e-26 sspD S small acid-soluble spore protein
JHKNLHEE_03681 1.9e-124 ykrK S Domain of unknown function (DUF1836)
JHKNLHEE_03682 3.5e-155 htpX O Belongs to the peptidase M48B family
JHKNLHEE_03683 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
JHKNLHEE_03684 1.2e-10 ydfR S Protein of unknown function (DUF421)
JHKNLHEE_03685 4.1e-18 ykzE
JHKNLHEE_03686 1.6e-188 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
JHKNLHEE_03687 0.0 kinE 2.7.13.3 T Histidine kinase
JHKNLHEE_03688 1.3e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JHKNLHEE_03690 8.2e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JHKNLHEE_03691 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
JHKNLHEE_03692 3.3e-149 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
JHKNLHEE_03693 3.4e-230 mtnE 2.6.1.83 E Aminotransferase
JHKNLHEE_03694 3.4e-230 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
JHKNLHEE_03695 3.2e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
JHKNLHEE_03696 8e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
JHKNLHEE_03697 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
JHKNLHEE_03698 5.4e-50 XK27_09985 S Protein of unknown function (DUF1232)
JHKNLHEE_03699 6.4e-09 S Spo0E like sporulation regulatory protein
JHKNLHEE_03700 9.5e-53 eag
JHKNLHEE_03701 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
JHKNLHEE_03702 1.4e-130 ythP V ABC transporter
JHKNLHEE_03703 1.3e-202 ythQ U Bacterial ABC transporter protein EcsB
JHKNLHEE_03704 2.1e-225 pbuO S permease
JHKNLHEE_03705 3.9e-270 pepV 3.5.1.18 E Dipeptidase
JHKNLHEE_03706 1.5e-172 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
JHKNLHEE_03707 3e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JHKNLHEE_03708 2.6e-50 ytlQ
JHKNLHEE_03709 1.2e-137 yqjF S Uncharacterized conserved protein (COG2071)
JHKNLHEE_03710 1.9e-139 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JHKNLHEE_03711 4.5e-24 yqzJ
JHKNLHEE_03712 3.4e-233 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JHKNLHEE_03713 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JHKNLHEE_03714 3.1e-122 yetF1 S membrane
JHKNLHEE_03715 2.8e-07 S Protein of unknown function (DUF421)
JHKNLHEE_03716 7.9e-70 S Protein of unknown function (DUF421)
JHKNLHEE_03717 5.4e-286 clsA_1 I PLD-like domain
JHKNLHEE_03718 1.4e-98 S Protein of unknown function (DUF421)
JHKNLHEE_03719 3.5e-42 S Putative amidase domain
JHKNLHEE_03720 1.8e-206 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
JHKNLHEE_03721 9.3e-48 S SMI1-KNR4 cell-wall
JHKNLHEE_03726 7.8e-08
JHKNLHEE_03734 2e-08
JHKNLHEE_03738 1.8e-50 L Transposase and inactivated derivatives, TnpA family
JHKNLHEE_03739 1.7e-76
JHKNLHEE_03740 2.6e-80 spoVAC S stage V sporulation protein AC
JHKNLHEE_03741 4.1e-78 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
JHKNLHEE_03742 6.3e-107 K TipAS antibiotic-recognition domain
JHKNLHEE_03743 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
JHKNLHEE_03745 1.2e-58
JHKNLHEE_03746 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
JHKNLHEE_03747 1.7e-66 ydeP3 K Transcriptional regulator
JHKNLHEE_03748 3.9e-84 cotF M Spore coat protein
JHKNLHEE_03750 8.3e-160 yybS S membrane
JHKNLHEE_03751 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
JHKNLHEE_03752 2.2e-73 rplI J binds to the 23S rRNA
JHKNLHEE_03753 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JHKNLHEE_03754 2.1e-219 yeaN P COG2807 Cyanate permease
JHKNLHEE_03755 7.2e-15 yycC K YycC-like protein
JHKNLHEE_03757 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
JHKNLHEE_03758 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
JHKNLHEE_03759 1.6e-54 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JHKNLHEE_03760 4.3e-247 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JHKNLHEE_03765 1.5e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JHKNLHEE_03766 0.0 vicK 2.7.13.3 T Histidine kinase
JHKNLHEE_03767 4.4e-258 yycH S protein conserved in bacteria
JHKNLHEE_03768 3.6e-154 yycI S protein conserved in bacteria
JHKNLHEE_03769 7.4e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
JHKNLHEE_03770 1.3e-216 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JHKNLHEE_03771 3.4e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
JHKNLHEE_03772 2.6e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
JHKNLHEE_03773 2.8e-260 rocE E amino acid
JHKNLHEE_03774 2e-166 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
JHKNLHEE_03776 5e-188 S aspartate phosphatase
JHKNLHEE_03777 8.4e-84 yycN 2.3.1.128 K Acetyltransferase
JHKNLHEE_03778 3.8e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
JHKNLHEE_03779 1.2e-208 yycP
JHKNLHEE_03780 8.2e-30 yycQ S Protein of unknown function (DUF2651)
JHKNLHEE_03782 6.7e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
JHKNLHEE_03783 8.8e-31
JHKNLHEE_03784 1.1e-09 S YyzF-like protein
JHKNLHEE_03785 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JHKNLHEE_03787 2.4e-25 I PLD-like domain
JHKNLHEE_03788 1.8e-45 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
JHKNLHEE_03789 2.2e-176 nlaXM 2.1.1.37 H C-5 cytosine-specific DNA methylase
JHKNLHEE_03790 2e-52 L EcoRII C terminal
JHKNLHEE_03791 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
JHKNLHEE_03792 7.6e-13
JHKNLHEE_03793 1.3e-128 yydK K Transcriptional regulator
JHKNLHEE_03794 2.4e-19 bglF G phosphotransferase system
JHKNLHEE_03795 2e-290 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JHKNLHEE_03796 3.8e-287 ahpF O Alkyl hydroperoxide reductase
JHKNLHEE_03797 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
JHKNLHEE_03798 4.3e-269 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JHKNLHEE_03799 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
JHKNLHEE_03800 1.5e-302 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
JHKNLHEE_03801 7.3e-127 gntR K transcriptional
JHKNLHEE_03802 2.1e-205 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
JHKNLHEE_03803 3.7e-193 yxaB GM Polysaccharide pyruvyl transferase
JHKNLHEE_03804 2.6e-118 yxaC M effector of murein hydrolase
JHKNLHEE_03805 8.9e-50 S LrgA family
JHKNLHEE_03806 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
JHKNLHEE_03807 1e-198 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JHKNLHEE_03808 7.1e-101 yxaF K Transcriptional regulator
JHKNLHEE_03809 6.4e-198 yxaG 1.13.11.24 S AraC-like ligand binding domain
JHKNLHEE_03810 2.8e-224 P Protein of unknown function (DUF418)
JHKNLHEE_03811 6.9e-75 yxaI S membrane protein domain
JHKNLHEE_03812 1.8e-64 S Family of unknown function (DUF5391)
JHKNLHEE_03813 9.9e-92 S PQQ-like domain
JHKNLHEE_03814 4.5e-29 yxaI S membrane protein domain
JHKNLHEE_03815 1.9e-245 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
JHKNLHEE_03816 1.2e-208 yxbF K Bacterial regulatory proteins, tetR family
JHKNLHEE_03817 2.6e-18 IQ Enoyl-(Acyl carrier protein) reductase
JHKNLHEE_03819 0.0 htpG O Molecular chaperone. Has ATPase activity
JHKNLHEE_03820 3.6e-244 csbC EGP Major facilitator Superfamily
JHKNLHEE_03821 1.9e-47 yxcD S Protein of unknown function (DUF2653)
JHKNLHEE_03823 1.9e-175 iolS C Aldo keto reductase
JHKNLHEE_03824 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
JHKNLHEE_03825 3e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
JHKNLHEE_03826 2.3e-153 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
JHKNLHEE_03827 2.5e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
JHKNLHEE_03828 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
JHKNLHEE_03829 4.7e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
JHKNLHEE_03830 6.2e-233 iolF EGP Major facilitator Superfamily
JHKNLHEE_03831 2.3e-195 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
JHKNLHEE_03832 3.3e-166 iolH G Xylose isomerase-like TIM barrel
JHKNLHEE_03833 8e-146 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
JHKNLHEE_03834 4.6e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
JHKNLHEE_03835 4.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JHKNLHEE_03836 1.2e-177 T PhoQ Sensor
JHKNLHEE_03837 9.7e-138 yxdL V ABC transporter, ATP-binding protein
JHKNLHEE_03838 0.0 yxdM V ABC transporter (permease)
JHKNLHEE_03839 1.5e-58 yxeA S Protein of unknown function (DUF1093)
JHKNLHEE_03840 2.3e-176 fhuD P ABC transporter
JHKNLHEE_03841 8.5e-69
JHKNLHEE_03842 1.9e-16 yxeD
JHKNLHEE_03843 1.3e-20 yxeE
JHKNLHEE_03846 6.2e-151 yidA S hydrolases of the HAD superfamily
JHKNLHEE_03847 5.9e-188 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
JHKNLHEE_03848 2.2e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JHKNLHEE_03849 8.9e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JHKNLHEE_03850 4.6e-143 yxeM M Belongs to the bacterial solute-binding protein 3 family
JHKNLHEE_03851 2.7e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
JHKNLHEE_03852 1.7e-131 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
JHKNLHEE_03853 4.7e-213 yxeP 3.5.1.47 E hydrolase activity
JHKNLHEE_03854 8.6e-251 yxeQ S MmgE/PrpD family
JHKNLHEE_03855 4.1e-198 eutH E Ethanolamine utilisation protein, EutH
JHKNLHEE_03856 2.4e-150 yxxB S Domain of Unknown Function (DUF1206)
JHKNLHEE_03857 1.8e-116 yxxB S Domain of Unknown Function (DUF1206)
JHKNLHEE_03858 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
JHKNLHEE_03859 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JHKNLHEE_03860 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JHKNLHEE_03861 3.6e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
JHKNLHEE_03862 1e-53 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
JHKNLHEE_03863 1.4e-42 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
JHKNLHEE_03864 1e-20 S Domain of unknown function (DUF5082)
JHKNLHEE_03865 4.7e-39 yxiC S Family of unknown function (DUF5344)
JHKNLHEE_03866 5.2e-210 S nuclease activity
JHKNLHEE_03867 5.5e-53
JHKNLHEE_03868 3.1e-296 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JHKNLHEE_03869 2.8e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JHKNLHEE_03870 4.5e-71 yxiE T Belongs to the universal stress protein A family
JHKNLHEE_03871 1.5e-164 yxxF EG EamA-like transporter family
JHKNLHEE_03872 0.0 wapA M COG3209 Rhs family protein
JHKNLHEE_03873 1.5e-71 yxxG
JHKNLHEE_03874 4.9e-84
JHKNLHEE_03875 6.4e-63
JHKNLHEE_03876 3.7e-75 yxiG
JHKNLHEE_03877 2e-139
JHKNLHEE_03878 1.6e-93 yxiI S Protein of unknown function (DUF2716)
JHKNLHEE_03879 5.7e-46 yxiJ S YxiJ-like protein
JHKNLHEE_03882 3.5e-208 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
JHKNLHEE_03883 4.3e-264 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
JHKNLHEE_03884 2.3e-229 yxiO S COG2270 Permeases of the major facilitator superfamily
JHKNLHEE_03885 1.2e-110
JHKNLHEE_03886 2.3e-139 licT K transcriptional antiterminator
JHKNLHEE_03887 2.1e-51 exoK GH16 M licheninase activity
JHKNLHEE_03888 6.6e-83 exoK GH16 M licheninase activity
JHKNLHEE_03889 6.6e-224 citH C Citrate transporter
JHKNLHEE_03890 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
JHKNLHEE_03891 3e-47 yxiS
JHKNLHEE_03892 6.8e-103 T Domain of unknown function (DUF4163)
JHKNLHEE_03893 7.8e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JHKNLHEE_03894 7.1e-27 S Protein of unknown function (DUF1657)
JHKNLHEE_03895 9.4e-161 cat P Catalase
JHKNLHEE_03896 1.5e-72 EG Spore germination protein
JHKNLHEE_03897 8.2e-32 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
JHKNLHEE_03898 6e-44 tnpIS3 L Transposase
JHKNLHEE_03899 1.5e-24 S Protein of unknown function (DUF2642)
JHKNLHEE_03900 1.4e-45 L transposase activity
JHKNLHEE_03901 8.1e-31 S Protein of unknown function (DUF2564)
JHKNLHEE_03903 1.3e-72 L Integrase core domain
JHKNLHEE_03907 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
JHKNLHEE_03908 1.7e-249 ywaD 3.4.11.10, 3.4.11.6 S PA domain
JHKNLHEE_03909 1.9e-158 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JHKNLHEE_03910 2.6e-10 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JHKNLHEE_03911 4e-87 ywaE K Transcriptional regulator
JHKNLHEE_03912 9.6e-43 ywaF S Integral membrane protein
JHKNLHEE_03913 2.4e-40 ywaF S Integral membrane protein
JHKNLHEE_03914 1.9e-166 gspA M General stress
JHKNLHEE_03915 4e-153 sacY K transcriptional antiterminator
JHKNLHEE_03916 4.4e-242 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JHKNLHEE_03917 2.1e-134 epr 3.4.21.62 O Belongs to the peptidase S8 family
JHKNLHEE_03918 1.6e-61 epr 3.4.21.62 O Belongs to the peptidase S8 family
JHKNLHEE_03919 9.5e-242 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JHKNLHEE_03920 4.4e-67 ywbC 4.4.1.5 E glyoxalase
JHKNLHEE_03921 4.5e-219 ywbD 2.1.1.191 J Methyltransferase
JHKNLHEE_03922 2.3e-27 ywbE S Uncharacterized conserved protein (DUF2196)
JHKNLHEE_03923 4.2e-68 ywbF EGP Major facilitator Superfamily
JHKNLHEE_03924 1.2e-122 ywbF EGP Major facilitator Superfamily
JHKNLHEE_03925 6.8e-111 ywbG M effector of murein hydrolase
JHKNLHEE_03926 1.9e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
JHKNLHEE_03927 4.3e-153 ywbI K Transcriptional regulator
JHKNLHEE_03928 1.2e-141 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JHKNLHEE_03929 2.5e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
JHKNLHEE_03930 2.3e-249 P COG0672 High-affinity Fe2 Pb2 permease
JHKNLHEE_03931 7.9e-184 ycdO P periplasmic lipoprotein involved in iron transport
JHKNLHEE_03932 2.5e-223 ywbN P Dyp-type peroxidase family protein
JHKNLHEE_03933 2.4e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
JHKNLHEE_03934 2.6e-267 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JHKNLHEE_03935 6.4e-48 ywcB S Protein of unknown function, DUF485
JHKNLHEE_03937 4.7e-120 ywcC K transcriptional regulator
JHKNLHEE_03938 9.5e-60 gtcA S GtrA-like protein
JHKNLHEE_03939 3.4e-302 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
JHKNLHEE_03940 1e-35 ywzA S membrane
JHKNLHEE_03941 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
JHKNLHEE_03942 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JHKNLHEE_03943 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
JHKNLHEE_03944 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
JHKNLHEE_03945 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
JHKNLHEE_03946 8.6e-202 rodA D Belongs to the SEDS family
JHKNLHEE_03947 6.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
JHKNLHEE_03948 9.5e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JHKNLHEE_03949 0.0 vpr O Belongs to the peptidase S8 family
JHKNLHEE_03952 1e-148 sacT K transcriptional antiterminator
JHKNLHEE_03953 3.3e-138 focA P Formate/nitrite transporter
JHKNLHEE_03954 1.2e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JHKNLHEE_03955 2.1e-287 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
JHKNLHEE_03956 2e-28 ywdA
JHKNLHEE_03957 3e-145 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
JHKNLHEE_03958 8.2e-57 pex K Transcriptional regulator PadR-like family
JHKNLHEE_03959 3.4e-112 ywdD
JHKNLHEE_03961 7.2e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
JHKNLHEE_03962 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JHKNLHEE_03963 5e-262 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
JHKNLHEE_03964 7.7e-49 ywdI S Family of unknown function (DUF5327)
JHKNLHEE_03965 3.7e-238 ywdJ F Xanthine uracil
JHKNLHEE_03966 4.3e-59 ywdK S small membrane protein
JHKNLHEE_03967 1.7e-72 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
JHKNLHEE_03968 1.8e-144 spsA M Spore Coat
JHKNLHEE_03969 8.9e-267 spsB M Capsule polysaccharide biosynthesis protein
JHKNLHEE_03970 2.5e-222 spsC E Belongs to the DegT DnrJ EryC1 family
JHKNLHEE_03971 3.7e-162 spsD 2.3.1.210 K Spore Coat
JHKNLHEE_03972 2.1e-213 spsE 2.5.1.56 M acid synthase
JHKNLHEE_03973 2.9e-128 spsF M Spore Coat
JHKNLHEE_03974 2e-186 spsG M Spore Coat
JHKNLHEE_03975 2.1e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JHKNLHEE_03976 5.7e-180 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
JHKNLHEE_03977 2.2e-159 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
JHKNLHEE_03978 1.3e-86 spsL 5.1.3.13 M Spore Coat
JHKNLHEE_03979 1.2e-77
JHKNLHEE_03980 2.4e-203 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
JHKNLHEE_03981 2.3e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
JHKNLHEE_03982 0.0 rocB E arginine degradation protein
JHKNLHEE_03983 5.7e-261 lysP E amino acid
JHKNLHEE_03984 9.6e-204 ywfA EGP Major facilitator Superfamily
JHKNLHEE_03985 4.3e-112 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
JHKNLHEE_03986 1.2e-120 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
JHKNLHEE_03987 5.6e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JHKNLHEE_03988 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
JHKNLHEE_03989 1.9e-209 bacE EGP Major facilitator Superfamily
JHKNLHEE_03990 5.8e-230 ywfG 2.6.1.83 E Aminotransferase class I and II
JHKNLHEE_03991 1.3e-137 IQ Enoyl-(Acyl carrier protein) reductase
JHKNLHEE_03992 1.1e-146 ywfI C May function as heme-dependent peroxidase
JHKNLHEE_03993 6.2e-174 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
JHKNLHEE_03994 9.2e-164 cysL K Transcriptional regulator
JHKNLHEE_03995 1.5e-155 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
JHKNLHEE_03996 5.7e-158 ywfM EG EamA-like transporter family
JHKNLHEE_03997 1.8e-107 rsfA_1
JHKNLHEE_03998 3.1e-36 ywzC S Belongs to the UPF0741 family
JHKNLHEE_03999 1.9e-255 ywfO S COG1078 HD superfamily phosphohydrolases
JHKNLHEE_04000 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
JHKNLHEE_04001 6.2e-79 yffB K Transcriptional regulator
JHKNLHEE_04002 9.2e-235 mmr U Major Facilitator Superfamily
JHKNLHEE_04004 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JHKNLHEE_04005 4.7e-70 ywhA K Transcriptional regulator
JHKNLHEE_04006 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
JHKNLHEE_04007 5.1e-119 ywhC S Peptidase family M50
JHKNLHEE_04008 2e-94 ywhD S YwhD family
JHKNLHEE_04009 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JHKNLHEE_04010 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JHKNLHEE_04011 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
JHKNLHEE_04013 7.5e-86 S aspartate phosphatase
JHKNLHEE_04014 8.9e-187 ywhK CO amine dehydrogenase activity
JHKNLHEE_04015 1.2e-242 ywhL CO amine dehydrogenase activity
JHKNLHEE_04017 8e-246 L Peptidase, M16
JHKNLHEE_04018 1.2e-214 2.7.1.26, 2.7.7.2 L Peptidase, M16
JHKNLHEE_04019 1.6e-233 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
JHKNLHEE_04020 1.3e-131 cbiO V ABC transporter
JHKNLHEE_04022 4.9e-270 C Fe-S oxidoreductases
JHKNLHEE_04023 1e-07 S Bacteriocin subtilosin A
JHKNLHEE_04024 4.7e-73 ywiB S protein conserved in bacteria
JHKNLHEE_04025 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
JHKNLHEE_04026 3.9e-213 narK P COG2223 Nitrate nitrite transporter
JHKNLHEE_04027 2e-129 fnr K helix_turn_helix, cAMP Regulatory protein
JHKNLHEE_04028 1.7e-139 ywiC S YwiC-like protein
JHKNLHEE_04029 7e-86 arfM T cyclic nucleotide binding
JHKNLHEE_04030 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JHKNLHEE_04031 1.9e-296 narH 1.7.5.1 C Nitrate reductase, beta
JHKNLHEE_04032 1.6e-94 narJ 1.7.5.1 C nitrate reductase
JHKNLHEE_04033 3.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
JHKNLHEE_04034 7.9e-285 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JHKNLHEE_04035 0.0 ywjA V ABC transporter
JHKNLHEE_04036 5.9e-94 ywjB H RibD C-terminal domain
JHKNLHEE_04037 2.7e-42 ywjC
JHKNLHEE_04038 2.5e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
JHKNLHEE_04039 1.1e-212 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
JHKNLHEE_04040 0.0 fadF C COG0247 Fe-S oxidoreductase
JHKNLHEE_04041 1.4e-209 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
JHKNLHEE_04042 1.4e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
JHKNLHEE_04043 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
JHKNLHEE_04045 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
JHKNLHEE_04046 3e-238 3.2.1.11 GH66 G Glycosyl hydrolase family 66
JHKNLHEE_04047 7.7e-80 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
JHKNLHEE_04048 1e-153 yusV 3.6.3.34 HP ABC transporter
JHKNLHEE_04049 1.9e-66 S YusW-like protein
JHKNLHEE_04050 7.9e-300 pepF2 E COG1164 Oligoendopeptidase F
JHKNLHEE_04051 2e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JHKNLHEE_04052 2.7e-79 dps P Ferritin-like domain
JHKNLHEE_04053 4.4e-234 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JHKNLHEE_04054 5.7e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JHKNLHEE_04055 9.7e-250 cssS 2.7.13.3 T PhoQ Sensor
JHKNLHEE_04056 1.3e-157 yuxN K Transcriptional regulator
JHKNLHEE_04057 5.6e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
JHKNLHEE_04058 3.9e-24 S Protein of unknown function (DUF3970)
JHKNLHEE_04059 1.1e-240 gerAA EG Spore germination protein
JHKNLHEE_04060 1.1e-195 gerAB E Spore germination protein
JHKNLHEE_04061 2.8e-178 gerAC S Spore germination B3/ GerAC like, C-terminal
JHKNLHEE_04062 8.1e-106 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JHKNLHEE_04063 1.6e-186 vraS 2.7.13.3 T Histidine kinase
JHKNLHEE_04064 9.5e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
JHKNLHEE_04065 3.1e-116 liaG S Putative adhesin
JHKNLHEE_04066 3.6e-104 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
JHKNLHEE_04067 7.3e-62 liaI S membrane
JHKNLHEE_04068 5.9e-225 yvqJ EGP Major facilitator Superfamily
JHKNLHEE_04069 3.9e-99 yvqK 2.5.1.17 S Adenosyltransferase
JHKNLHEE_04070 2.1e-244 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
JHKNLHEE_04071 1.9e-184 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JHKNLHEE_04072 2.6e-169 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
JHKNLHEE_04073 1.5e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JHKNLHEE_04074 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
JHKNLHEE_04075 0.0 T PhoQ Sensor
JHKNLHEE_04076 1.2e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JHKNLHEE_04077 3.6e-22
JHKNLHEE_04078 2.3e-96 yvrI K RNA polymerase
JHKNLHEE_04079 2.4e-19 S YvrJ protein family
JHKNLHEE_04080 2.3e-228 oxdC 4.1.1.2 G Oxalate decarboxylase
JHKNLHEE_04081 3.2e-63 yvrL S Regulatory protein YrvL
JHKNLHEE_04082 1.5e-209 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
JHKNLHEE_04083 1.6e-123 macB V ABC transporter, ATP-binding protein
JHKNLHEE_04084 5.8e-174 M Efflux transporter rnd family, mfp subunit
JHKNLHEE_04085 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
JHKNLHEE_04086 2.5e-173 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JHKNLHEE_04087 9.6e-181 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JHKNLHEE_04088 2.6e-177 fhuD P ABC transporter
JHKNLHEE_04090 4.9e-236 yvsH E Arginine ornithine antiporter
JHKNLHEE_04091 6.5e-16 S Small spore protein J (Spore_SspJ)
JHKNLHEE_04092 2.3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
JHKNLHEE_04093 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
JHKNLHEE_04094 2.3e-165 yvgK P COG1910 Periplasmic molybdate-binding protein domain
JHKNLHEE_04095 1.2e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
JHKNLHEE_04096 2.4e-119 modB P COG4149 ABC-type molybdate transport system, permease component
JHKNLHEE_04097 9.4e-155 yvgN S reductase
JHKNLHEE_04098 5.4e-86 yvgO
JHKNLHEE_04099 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
JHKNLHEE_04100 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
JHKNLHEE_04101 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JHKNLHEE_04102 0.0 helD 3.6.4.12 L DNA helicase
JHKNLHEE_04103 4.1e-107 yvgT S membrane
JHKNLHEE_04104 8.5e-72 bdbC O Required for disulfide bond formation in some proteins
JHKNLHEE_04105 1.6e-104 bdbD O Thioredoxin
JHKNLHEE_04106 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
JHKNLHEE_04107 0.0 copA 3.6.3.54 P P-type ATPase
JHKNLHEE_04108 5.9e-29 copZ P Copper resistance protein CopZ
JHKNLHEE_04109 2.2e-48 csoR S transcriptional
JHKNLHEE_04110 6.4e-193 yvaA 1.1.1.371 S Oxidoreductase
JHKNLHEE_04111 1.6e-117 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JHKNLHEE_04112 1e-105 yvaC S Fusaric acid resistance protein-like
JHKNLHEE_04113 7.9e-217 yvaC S Fusaric acid resistance protein-like
JHKNLHEE_04114 5.7e-73 yvaD S Family of unknown function (DUF5360)
JHKNLHEE_04115 6.9e-54 yvaE P Small Multidrug Resistance protein
JHKNLHEE_04116 2.1e-94 K Bacterial regulatory proteins, tetR family
JHKNLHEE_04117 4.2e-87 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JHKNLHEE_04118 2.2e-14 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JHKNLHEE_04120 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JHKNLHEE_04121 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
JHKNLHEE_04122 9.6e-143 est 3.1.1.1 S Carboxylesterase
JHKNLHEE_04123 2.4e-23 secG U Preprotein translocase subunit SecG
JHKNLHEE_04124 3.4e-151 yvaM S Serine aminopeptidase, S33
JHKNLHEE_04125 9.8e-36 yvzC K Transcriptional
JHKNLHEE_04126 2.6e-68 K transcriptional
JHKNLHEE_04127 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
JHKNLHEE_04128 2.2e-54 yodB K transcriptional
JHKNLHEE_04129 1.2e-19 NT chemotaxis protein
JHKNLHEE_04130 2.2e-170 NT chemotaxis protein
JHKNLHEE_04131 1.5e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
JHKNLHEE_04132 4.2e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
JHKNLHEE_04133 1.6e-109 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
JHKNLHEE_04134 9.2e-209 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
JHKNLHEE_04135 7.4e-60 yvbF K Belongs to the GbsR family
JHKNLHEE_04136 7.9e-13 S Sporulation delaying protein SdpA
JHKNLHEE_04137 4.9e-171
JHKNLHEE_04138 4.4e-08
JHKNLHEE_04139 3.3e-96 sdpI S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
JHKNLHEE_04140 4.5e-45 sdpR K transcriptional
JHKNLHEE_04141 8.7e-114 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
JHKNLHEE_04142 7.9e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
JHKNLHEE_04143 1.2e-104 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
JHKNLHEE_04144 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
JHKNLHEE_04145 3.5e-97 yvbF K Belongs to the GbsR family
JHKNLHEE_04146 6e-101 yvbG U UPF0056 membrane protein
JHKNLHEE_04147 1.9e-112 yvbH S YvbH-like oligomerisation region
JHKNLHEE_04148 2.2e-120 exoY M Membrane
JHKNLHEE_04149 8.1e-252 tcaA S response to antibiotic
JHKNLHEE_04150 8.3e-76 yvbK 3.1.3.25 K acetyltransferase
JHKNLHEE_04151 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
JHKNLHEE_04152 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
JHKNLHEE_04153 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
JHKNLHEE_04154 1.6e-216 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
JHKNLHEE_04155 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
JHKNLHEE_04156 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
JHKNLHEE_04157 1.6e-252 araE EGP Major facilitator Superfamily
JHKNLHEE_04158 5.5e-203 araR K transcriptional
JHKNLHEE_04159 5.8e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JHKNLHEE_04160 9.6e-158 yvbU K Transcriptional regulator
JHKNLHEE_04161 1.2e-155 yvbV EG EamA-like transporter family
JHKNLHEE_04162 5.8e-29 S Protein of unknown function (DUF1657)
JHKNLHEE_04165 6.2e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
JHKNLHEE_04166 1.4e-195 yvbX S Glycosyl hydrolase
JHKNLHEE_04167 1.5e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
JHKNLHEE_04168 3.5e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
JHKNLHEE_04169 6.5e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
JHKNLHEE_04170 5.8e-29 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JHKNLHEE_04171 1.2e-152 rsbQ S Alpha/beta hydrolase family
JHKNLHEE_04172 2.7e-195 rsbU 3.1.3.3 T response regulator
JHKNLHEE_04173 1.3e-248 galA 3.2.1.89 G arabinogalactan
JHKNLHEE_04174 0.0 lacA 3.2.1.23 G beta-galactosidase
JHKNLHEE_04175 7.2e-150 ganQ P transport
JHKNLHEE_04176 6.5e-232 malC P COG1175 ABC-type sugar transport systems, permease components
JHKNLHEE_04177 2.7e-230 cycB G COG2182 Maltose-binding periplasmic proteins domains
JHKNLHEE_04178 1.8e-184 lacR K Transcriptional regulator
JHKNLHEE_04179 2.7e-113 yvfI K COG2186 Transcriptional regulators
JHKNLHEE_04180 7.5e-308 yvfH C L-lactate permease
JHKNLHEE_04181 8.8e-240 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
JHKNLHEE_04182 1e-31 yvfG S YvfG protein
JHKNLHEE_04183 3.7e-187 yvfF GM Exopolysaccharide biosynthesis protein
JHKNLHEE_04184 6.9e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
JHKNLHEE_04185 6.6e-55 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
JHKNLHEE_04186 2.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
JHKNLHEE_04187 3.1e-257 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JHKNLHEE_04188 1.2e-191 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
JHKNLHEE_04189 1.1e-200 epsI GM pyruvyl transferase
JHKNLHEE_04190 2e-194 epsH GT2 S Glycosyltransferase like family 2
JHKNLHEE_04191 2.4e-206 epsG S EpsG family
JHKNLHEE_04192 8.4e-218 epsF GT4 M Glycosyl transferases group 1
JHKNLHEE_04193 1.6e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
JHKNLHEE_04194 1.1e-222 epsD GT4 M Glycosyl transferase 4-like
JHKNLHEE_04195 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
JHKNLHEE_04196 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
JHKNLHEE_04197 8.9e-122 ywqC M biosynthesis protein
JHKNLHEE_04198 1.4e-75 slr K transcriptional
JHKNLHEE_04199 1.4e-281 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
JHKNLHEE_04201 1.7e-92 padC Q Phenolic acid decarboxylase
JHKNLHEE_04202 1.3e-73 MA20_18690 S Protein of unknown function (DUF3237)
JHKNLHEE_04203 3e-122 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
JHKNLHEE_04204 9e-264 pbpE V Beta-lactamase
JHKNLHEE_04205 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
JHKNLHEE_04206 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
JHKNLHEE_04207 1.8e-295 yveA E amino acid
JHKNLHEE_04208 7.4e-106 yvdT K Transcriptional regulator
JHKNLHEE_04209 1.6e-49 ykkC P Small Multidrug Resistance protein
JHKNLHEE_04210 7.1e-50 sugE P Small Multidrug Resistance protein
JHKNLHEE_04211 1.3e-72 yvdQ S Protein of unknown function (DUF3231)
JHKNLHEE_04213 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
JHKNLHEE_04214 1.3e-114 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
JHKNLHEE_04215 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
JHKNLHEE_04216 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
JHKNLHEE_04217 3.2e-153 malA S Protein of unknown function (DUF1189)
JHKNLHEE_04218 3.9e-148 malD P transport
JHKNLHEE_04219 4.5e-244 malC P COG1175 ABC-type sugar transport systems, permease components
JHKNLHEE_04220 2.4e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
JHKNLHEE_04221 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
JHKNLHEE_04222 3.3e-172 yvdE K Transcriptional regulator
JHKNLHEE_04223 1.6e-105 yvdD 3.2.2.10 S Belongs to the LOG family
JHKNLHEE_04224 1.5e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
JHKNLHEE_04225 1.1e-287 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
JHKNLHEE_04226 3.1e-104 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
JHKNLHEE_04227 8.7e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JHKNLHEE_04228 0.0 yxdM V ABC transporter (permease)
JHKNLHEE_04229 2.1e-140 yvcR V ABC transporter, ATP-binding protein
JHKNLHEE_04230 1.3e-196 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
JHKNLHEE_04231 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JHKNLHEE_04232 3.3e-32
JHKNLHEE_04233 4.9e-142 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
JHKNLHEE_04234 1.6e-36 crh G Phosphocarrier protein Chr
JHKNLHEE_04235 1.4e-170 whiA K May be required for sporulation
JHKNLHEE_04236 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
JHKNLHEE_04237 5.7e-166 rapZ S Displays ATPase and GTPase activities
JHKNLHEE_04238 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
JHKNLHEE_04239 9.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
JHKNLHEE_04240 1.1e-97 usp CBM50 M protein conserved in bacteria
JHKNLHEE_04241 5e-276 S COG0457 FOG TPR repeat
JHKNLHEE_04242 0.0 msbA2 3.6.3.44 V ABC transporter
JHKNLHEE_04244 0.0
JHKNLHEE_04245 1.6e-118
JHKNLHEE_04246 8.8e-113 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
JHKNLHEE_04247 1.4e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
JHKNLHEE_04248 1.1e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JHKNLHEE_04249 1.1e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JHKNLHEE_04250 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
JHKNLHEE_04251 1.5e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JHKNLHEE_04252 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
JHKNLHEE_04253 2.4e-220 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JHKNLHEE_04254 1.1e-138 yvpB NU protein conserved in bacteria
JHKNLHEE_04255 8.7e-119 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
JHKNLHEE_04256 1.6e-80 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
JHKNLHEE_04257 3.2e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
JHKNLHEE_04258 1.6e-163 yvoD P COG0370 Fe2 transport system protein B
JHKNLHEE_04259 1.2e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JHKNLHEE_04260 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JHKNLHEE_04261 8.6e-218 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
JHKNLHEE_04262 1e-128 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
JHKNLHEE_04263 3.6e-134 yvoA K transcriptional
JHKNLHEE_04264 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
JHKNLHEE_04265 4.2e-83 adcR K helix_turn_helix multiple antibiotic resistance protein
JHKNLHEE_04266 4.1e-231 cypX 1.14.15.13 C Cytochrome P450
JHKNLHEE_04267 1.8e-136 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
JHKNLHEE_04268 7.4e-86 yvmB K helix_turn_helix multiple antibiotic resistance protein
JHKNLHEE_04269 2.7e-203 yvmA EGP Major facilitator Superfamily
JHKNLHEE_04270 1.2e-50 yvlD S Membrane
JHKNLHEE_04271 2.6e-26 pspB KT PspC domain
JHKNLHEE_04272 9.2e-166 yvlB S Putative adhesin
JHKNLHEE_04273 8e-49 yvlA
JHKNLHEE_04274 5.7e-33 yvkN
JHKNLHEE_04275 2.9e-38 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)