ORF_ID e_value Gene_name EC_number CAZy COGs Description
LKAIADJA_00001 2e-64 EG Spore germination protein
LKAIADJA_00002 6e-44 tnpIS3 L Transposase
LKAIADJA_00003 1.3e-72 L Integrase core domain
LKAIADJA_00004 2.2e-241 gabR K Transcriptional regulator
LKAIADJA_00005 3e-159 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LKAIADJA_00006 1.3e-97 pdxT 4.3.3.6 F Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LKAIADJA_00007 1.4e-207 nupC F Nucleoside
LKAIADJA_00008 5.2e-78 ctsR K Transcriptional regulator CtsR
LKAIADJA_00009 8e-102 CP_0046 2.7.14.1 S UvrB/uvrC motif
LKAIADJA_00010 5e-182 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in proteins
LKAIADJA_00011 0.0 clpC O ATP-dependent Clp protease, ATP-binding subunit ClpC
LKAIADJA_00012 2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LKAIADJA_00013 3.5e-162 yacL S PIN domain
LKAIADJA_00014 2.7e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LKAIADJA_00015 2.5e-118 cysE 2.3.1.30 E Serine acetyltransferase
LKAIADJA_00016 1.1e-267 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
LKAIADJA_00017 2.7e-59 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LKAIADJA_00018 2e-116 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LKAIADJA_00019 7.2e-92 yacP S RNA-binding protein containing a PIN domain
LKAIADJA_00020 2.8e-81 sigH K Belongs to the sigma-70 factor family
LKAIADJA_00021 9.2e-23 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LKAIADJA_00022 1.2e-97 nusG K Participates in transcription elongation, termination and antitermination
LKAIADJA_00023 3.6e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LKAIADJA_00024 7.5e-121 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LKAIADJA_00025 1.2e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LKAIADJA_00026 1.8e-41 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LKAIADJA_00027 1.5e-104 rsmC 2.1.1.172 J Methyltransferase small domain
LKAIADJA_00028 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LKAIADJA_00029 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LKAIADJA_00030 7.9e-36 J ribosomal protein
LKAIADJA_00031 4.2e-71 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LKAIADJA_00032 1e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LKAIADJA_00033 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LKAIADJA_00034 7e-220 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LKAIADJA_00035 1.6e-224 E Peptidase dimerisation domain
LKAIADJA_00036 2e-222 kbl 2.3.1.29, 2.3.1.47 E COG0156 7-keto-8-aminopelargonate synthetase and related enzymes
LKAIADJA_00037 5.4e-73 S Chloramphenicol phosphotransferase-like protein
LKAIADJA_00038 8e-105 2.3.1.128 J Acetyltransferase (GNAT) domain
LKAIADJA_00039 1e-87 S Acetyltransferase (GNAT) domain
LKAIADJA_00040 1.2e-126 scoA 2.8.3.5 I Coenzyme A transferase
LKAIADJA_00041 7.7e-112 scoB 2.8.3.5 I Coenzyme A transferase
LKAIADJA_00042 4.5e-57
LKAIADJA_00043 5.4e-162 rapL 4.3.1.12 E Ornithine cyclodeaminase
LKAIADJA_00044 2.2e-168 cps2D 5.1.3.2 M NAD dependent epimerase dehydratase family protein
LKAIADJA_00045 0.0 tagX 2.7.8.12 M CDP-glycerol poly(glycerophosphate) glycerophosphotransferase
LKAIADJA_00046 1.7e-169 G Acyltransferase family
LKAIADJA_00047 1.5e-171 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LKAIADJA_00048 1.6e-305 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
LKAIADJA_00049 1.2e-45
LKAIADJA_00050 1.1e-139 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
LKAIADJA_00051 7.7e-46 ydhR S Putative mono-oxygenase ydhR
LKAIADJA_00052 2e-87
LKAIADJA_00053 3.2e-134 penP 3.5.2.6 V beta-lactamase
LKAIADJA_00054 1.1e-161 ywbI K Transcriptional regulator
LKAIADJA_00055 1.2e-169 K helix_turn _helix lactose operon repressor
LKAIADJA_00056 3.2e-107 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
LKAIADJA_00057 3.3e-175 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
LKAIADJA_00058 2.8e-180 G Bacterial extracellular solute-binding protein, family 7
LKAIADJA_00059 5.5e-81 G Tripartite ATP-independent periplasmic transporters, DctQ component
LKAIADJA_00060 4.7e-193 G Tripartite ATP-independent periplasmic transporter, DctM component
LKAIADJA_00061 3.6e-239 uxaC 5.3.1.12 G glucuronate isomerase
LKAIADJA_00062 6.6e-182 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
LKAIADJA_00063 2.4e-134 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LKAIADJA_00064 7.7e-131 galU 2.7.7.9 M Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. a glycolipid found in the membrane, which is also used as a membrane anchor for lipoteichoic acid (LTA) (By similarity)
LKAIADJA_00065 0.0 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
LKAIADJA_00066 7.9e-162 S membrane
LKAIADJA_00067 2e-185 mntH P H( )-stimulated, divalent metal cation uptake system
LKAIADJA_00068 5.7e-172 speB 3.5.3.11 E Arginase family
LKAIADJA_00069 1.3e-211 gluD 1.4.1.2, 1.4.1.3 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
LKAIADJA_00070 1.8e-227 cycA E permease
LKAIADJA_00071 3.5e-53 S Activator of Hsp90 ATPase homolog 1-like protein
LKAIADJA_00072 2.9e-173 EGP Major facilitator Superfamily
LKAIADJA_00073 7.3e-137 K LysR substrate binding domain
LKAIADJA_00074 2.7e-85 S Elongation factor G-binding protein, N-terminal
LKAIADJA_00075 2.9e-176 tdh 4.2.1.45 M epimerase dehydratase family
LKAIADJA_00076 3.2e-203 ilvE 2.6.1.42 E Aminotransferase
LKAIADJA_00077 2e-83 yjlB S Cupin
LKAIADJA_00078 7.4e-121 gph 3.1.3.18 S HAD-hyrolase-like
LKAIADJA_00079 1.9e-65
LKAIADJA_00080 2.8e-125 dck 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
LKAIADJA_00081 2.4e-110 dgk 2.7.1.113 F deoxynucleoside kinase
LKAIADJA_00082 9.4e-89 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LKAIADJA_00083 1.7e-151 ycsE S Sucrose-6F-phosphate phosphohydrolase
LKAIADJA_00084 7e-93 azo1 1.5.1.38 S Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADPH, but not NADH, as an electron donor for its activity (By similarity)
LKAIADJA_00085 2.6e-50
LKAIADJA_00086 2e-117
LKAIADJA_00087 1.7e-162 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
LKAIADJA_00088 5.8e-123 bshB2 S GlcNAc-PI de-N-acetylase
LKAIADJA_00089 1.2e-61 yojF S Protein of unknown function (DUF1806)
LKAIADJA_00090 3.3e-127 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LKAIADJA_00091 1.1e-107 hxlA 4.1.2.43 G Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate
LKAIADJA_00092 8.3e-91 hxlB 5.3.1.27 M SIS domain
LKAIADJA_00093 2.2e-240 2.7.8.12 GT2 M teichoic acid biosynthesis
LKAIADJA_00094 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LKAIADJA_00095 5e-57 proP EGP proline betaine transporter
LKAIADJA_00096 1.8e-72 XK27_01300 S ASCH
LKAIADJA_00097 1.3e-23 vraX S Family of unknown function
LKAIADJA_00098 1.2e-94 isaB
LKAIADJA_00099 2.4e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
LKAIADJA_00100 3.3e-126 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LKAIADJA_00101 1.3e-47 S Family of unknown function (DUF5327)
LKAIADJA_00102 1.8e-57 ywdK S membrane
LKAIADJA_00103 7.5e-264 E amino acid
LKAIADJA_00104 3.9e-34 K Transcriptional regulator PadR-like family
LKAIADJA_00105 4.8e-157 chrA P Chromate transporter
LKAIADJA_00106 2e-74 S Threonine/Serine exporter, ThrE
LKAIADJA_00107 3.4e-130 thrE S Putative threonine/serine exporter
LKAIADJA_00108 2e-143 ywfI C May function as heme-dependent peroxidase
LKAIADJA_00109 1.5e-175 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase activity
LKAIADJA_00110 5e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
LKAIADJA_00111 3.1e-168 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I Mevalonate kinase
LKAIADJA_00112 2.9e-179 mvaD 4.1.1.33 I decarboxylase
LKAIADJA_00113 1.7e-201 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
LKAIADJA_00114 5.6e-37 ywzC S Belongs to the UPF0741 family
LKAIADJA_00115 1.5e-133 IQ KR domain
LKAIADJA_00116 5.3e-226 P Major Facilitator Superfamily
LKAIADJA_00117 8.9e-295 araB G FGGY family of carbohydrate kinases, N-terminal domain
LKAIADJA_00118 1.4e-178 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LKAIADJA_00119 6.6e-173 iolS C Aldo/keto reductase family
LKAIADJA_00120 1.4e-98 ywqN S NADPH-dependent FMN reductase
LKAIADJA_00121 1.9e-83 2.7.6.3 K Acetyltransferase (GNAT) domain
LKAIADJA_00122 1.8e-253 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
LKAIADJA_00123 3.5e-91 ywhD S YwhD family
LKAIADJA_00124 6.1e-70 ywiB S Domain of unknown function (DUF1934)
LKAIADJA_00125 1.1e-308 argS 6.1.1.19 J Arginyl-tRNA synthetase
LKAIADJA_00126 1.5e-96 magIII L endonuclease III
LKAIADJA_00127 9.4e-145 btuF P ABC transporter
LKAIADJA_00128 5.2e-125 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKAIADJA_00129 8.8e-130 S Hydrolase
LKAIADJA_00130 2.4e-139 3.5.4.33, 3.8.1.5 I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LKAIADJA_00131 2.2e-82
LKAIADJA_00132 4.5e-121
LKAIADJA_00133 7.3e-136 3.5.4.33, 3.8.1.5 I Alpha/beta hydrolase family
LKAIADJA_00134 2e-59 sarA K Transcriptional
LKAIADJA_00135 8.5e-64 M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LKAIADJA_00136 1.2e-155 ydcZ S Putative inner membrane exporter, YdcZ
LKAIADJA_00137 3.1e-37
LKAIADJA_00138 1.1e-30 S Protein of unknown function (DUF2922)
LKAIADJA_00139 5.8e-29
LKAIADJA_00140 3.3e-95 L Integrase
LKAIADJA_00141 0.0 phaA 1.6.5.3 P monovalent cation H antiporter subunit A
LKAIADJA_00142 8.4e-67 mnhB2 P antiporter activity
LKAIADJA_00143 4.1e-35 phaC 1.6.5.3 P subunit C
LKAIADJA_00144 2.2e-263 mrpD CP subunit D
LKAIADJA_00145 3.7e-79 mrpE P subunit E
LKAIADJA_00146 1.9e-41 phaF P Subunit F
LKAIADJA_00147 1.6e-66 phaG P subunit G
LKAIADJA_00148 0.0 yjcE P NhaP-type Na H and K H
LKAIADJA_00149 3.5e-158 sitA P Belongs to the bacterial solute-binding protein 9 family
LKAIADJA_00150 4.9e-135 mtsC P ABC-type Mn2 Zn2 transport
LKAIADJA_00151 1.9e-127 3.6.3.35 P ABC transporter, ATP-binding protein
LKAIADJA_00152 1.4e-113 sirR K Transcriptional regulator
LKAIADJA_00153 4.3e-122 S Peptidase M50B-like
LKAIADJA_00154 3.4e-127 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
LKAIADJA_00156 5.9e-91 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
LKAIADJA_00158 6.8e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LKAIADJA_00159 4.2e-29 S Domain of unknown function (DUF4177)
LKAIADJA_00160 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
LKAIADJA_00161 2.8e-174 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
LKAIADJA_00163 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
LKAIADJA_00164 1.8e-81 S Protein of unknown function (DUF2690)
LKAIADJA_00165 1.7e-18 yjfB S Putative motility protein
LKAIADJA_00166 9.8e-166 yjfC O Predicted Zn-dependent protease (DUF2268)
LKAIADJA_00167 2.9e-102 yjgB S Domain of unknown function (DUF4309)
LKAIADJA_00168 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
LKAIADJA_00169 8.3e-72 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
LKAIADJA_00170 1.6e-94 yjgD S Protein of unknown function (DUF1641)
LKAIADJA_00174 1.6e-219 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
LKAIADJA_00175 1.1e-217 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
LKAIADJA_00176 3.1e-29
LKAIADJA_00177 1.3e-140 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
LKAIADJA_00178 9.5e-122 ybbM S transport system, permease component
LKAIADJA_00179 6.4e-134 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
LKAIADJA_00180 1.1e-175 yjlA EG Putative multidrug resistance efflux transporter
LKAIADJA_00181 1.1e-89 yjlB S Cupin domain
LKAIADJA_00182 7.1e-66 yjlC S Protein of unknown function (DUF1641)
LKAIADJA_00183 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
LKAIADJA_00184 6.7e-278 uxaC 5.3.1.12 G glucuronate isomerase
LKAIADJA_00185 1.3e-246 yjmB G symporter YjmB
LKAIADJA_00186 7.1e-189 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
LKAIADJA_00187 3.1e-192 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
LKAIADJA_00188 5.4e-211 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
LKAIADJA_00190 7e-130 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LKAIADJA_00191 1e-224 exuT G Sugar (and other) transporter
LKAIADJA_00192 1.4e-181 exuR K transcriptional
LKAIADJA_00193 1.9e-280 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
LKAIADJA_00194 3.2e-286 uxaA 4.2.1.7, 4.4.1.24 G Altronate
LKAIADJA_00195 1.3e-129 MA20_18170 S membrane transporter protein
LKAIADJA_00196 2.3e-78 yjoA S DinB family
LKAIADJA_00197 8.8e-245 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
LKAIADJA_00198 1e-212 S response regulator aspartate phosphatase
LKAIADJA_00200 1.2e-39 S YCII-related domain
LKAIADJA_00201 1.6e-158 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
LKAIADJA_00202 1.8e-60 yjqA S Bacterial PH domain
LKAIADJA_00203 2.3e-110 yjqB S Pfam:DUF867
LKAIADJA_00204 1.3e-159 ydbD P Catalase
LKAIADJA_00205 6.6e-110 xkdA E IrrE N-terminal-like domain
LKAIADJA_00206 9.2e-56 xre K Helix-turn-helix XRE-family like proteins
LKAIADJA_00208 6.3e-148 xkdB K sequence-specific DNA binding
LKAIADJA_00209 4.1e-118 xkdC L Bacterial dnaA protein
LKAIADJA_00212 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
LKAIADJA_00213 3.5e-83 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
LKAIADJA_00214 4.1e-139 xtmA L phage terminase small subunit
LKAIADJA_00215 2.2e-251 xtmB S phage terminase, large subunit
LKAIADJA_00216 2.4e-18 yqbA S portal protein
LKAIADJA_00217 1e-168 yqbA S portal protein
LKAIADJA_00218 1.6e-48 yqbA S portal protein
LKAIADJA_00219 3.5e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
LKAIADJA_00220 1.7e-168 xkdG S Phage capsid family
LKAIADJA_00221 9.6e-62 yqbG S Protein of unknown function (DUF3199)
LKAIADJA_00222 4.3e-64 yqbH S Domain of unknown function (DUF3599)
LKAIADJA_00223 4.9e-87 xkdI S Bacteriophage HK97-gp10, putative tail-component
LKAIADJA_00224 1.2e-76 xkdJ
LKAIADJA_00225 2.5e-256 xkdK S Phage tail sheath C-terminal domain
LKAIADJA_00226 6.1e-76 xkdM S Phage tail tube protein
LKAIADJA_00227 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
LKAIADJA_00228 0.0 xkdO L Transglycosylase SLT domain
LKAIADJA_00229 8.9e-116 xkdP S Lysin motif
LKAIADJA_00230 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
LKAIADJA_00231 2.1e-39 xkdR S Protein of unknown function (DUF2577)
LKAIADJA_00232 9.6e-71 xkdS S Protein of unknown function (DUF2634)
LKAIADJA_00233 6.2e-123 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
LKAIADJA_00234 1.4e-57 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
LKAIADJA_00235 4e-104 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
LKAIADJA_00236 6.7e-41
LKAIADJA_00237 0.0
LKAIADJA_00238 4.6e-52 xkdW S XkdW protein
LKAIADJA_00239 9.3e-22 xkdX
LKAIADJA_00240 5.8e-152 xepA
LKAIADJA_00241 1.8e-38 xhlA S Haemolysin XhlA
LKAIADJA_00242 9.3e-40 xhlB S SPP1 phage holin
LKAIADJA_00243 5e-162 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LKAIADJA_00244 6.7e-23 spoIISB S Stage II sporulation protein SB
LKAIADJA_00245 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
LKAIADJA_00246 7.6e-175 pit P phosphate transporter
LKAIADJA_00247 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
LKAIADJA_00248 9.8e-239 steT E amino acid
LKAIADJA_00249 1.8e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
LKAIADJA_00250 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LKAIADJA_00251 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LKAIADJA_00252 3.2e-213 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LKAIADJA_00253 2.6e-133 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
LKAIADJA_00254 5.1e-153 dppA E D-aminopeptidase
LKAIADJA_00255 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LKAIADJA_00256 3.6e-174 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LKAIADJA_00257 1.3e-187 dppD P Belongs to the ABC transporter superfamily
LKAIADJA_00258 0.0 dppE E ABC transporter substrate-binding protein
LKAIADJA_00259 2.9e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
LKAIADJA_00260 1.7e-199 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
LKAIADJA_00261 2.2e-165 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
LKAIADJA_00262 1.5e-186 ykfD E Belongs to the ABC transporter superfamily
LKAIADJA_00263 5.3e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
LKAIADJA_00264 1.7e-159 ykgA E Amidinotransferase
LKAIADJA_00265 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
LKAIADJA_00266 2.5e-225 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LKAIADJA_00268 1.9e-127 ykjA S Protein of unknown function (DUF421)
LKAIADJA_00269 9.7e-97 ykkA S Protein of unknown function (DUF664)
LKAIADJA_00270 1.5e-97 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LKAIADJA_00271 1.1e-53 ykkC P Multidrug resistance protein
LKAIADJA_00272 9.1e-50 ykkD P Multidrug resistance protein
LKAIADJA_00273 5.6e-169 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
LKAIADJA_00274 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LKAIADJA_00275 2.1e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LKAIADJA_00276 6.3e-70 ohrA O Organic hydroperoxide resistance protein
LKAIADJA_00277 1.7e-73 ohrR K COG1846 Transcriptional regulators
LKAIADJA_00278 8.4e-72 ohrB O Organic hydroperoxide resistance protein
LKAIADJA_00279 5.5e-83 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
LKAIADJA_00280 2.2e-100 5.4.2.11 G Belongs to the phosphoglycerate mutase family
LKAIADJA_00281 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LKAIADJA_00282 5e-176 isp O Belongs to the peptidase S8 family
LKAIADJA_00283 1.8e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LKAIADJA_00284 5.3e-136 ykoC P Cobalt transport protein
LKAIADJA_00285 7.2e-308 P ABC transporter, ATP-binding protein
LKAIADJA_00286 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
LKAIADJA_00287 5.1e-110 ykoF S YKOF-related Family
LKAIADJA_00288 1.8e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKAIADJA_00289 5.7e-159 ykoH 2.7.13.3 T Histidine kinase
LKAIADJA_00290 3e-67 ykoH 2.7.13.3 T Histidine kinase
LKAIADJA_00291 3.1e-69 ykoI S Peptidase propeptide and YPEB domain
LKAIADJA_00292 9.2e-84 ykoJ S Peptidase propeptide and YPEB domain
LKAIADJA_00295 2.2e-222 mgtE P Acts as a magnesium transporter
LKAIADJA_00296 1.4e-53 tnrA K transcriptional
LKAIADJA_00297 5.9e-18
LKAIADJA_00298 3.4e-25 ykoL
LKAIADJA_00299 1.3e-81 mhqR K transcriptional
LKAIADJA_00300 1.4e-217 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
LKAIADJA_00301 6.3e-97 ykoP G polysaccharide deacetylase
LKAIADJA_00302 6e-154 ykoQ S Calcineurin-like phosphoesterase superfamily domain
LKAIADJA_00303 0.0 ykoS
LKAIADJA_00304 2.1e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LKAIADJA_00305 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
LKAIADJA_00306 1.4e-159 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LKAIADJA_00307 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
LKAIADJA_00308 1.7e-108 ykoX S membrane-associated protein
LKAIADJA_00309 4.6e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
LKAIADJA_00310 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LKAIADJA_00311 1.5e-105 rsgI S Anti-sigma factor N-terminus
LKAIADJA_00312 1.9e-26 sspD S small acid-soluble spore protein
LKAIADJA_00313 1.9e-124 ykrK S Domain of unknown function (DUF1836)
LKAIADJA_00314 3.5e-155 htpX O Belongs to the peptidase M48B family
LKAIADJA_00315 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
LKAIADJA_00316 1.2e-10 ydfR S Protein of unknown function (DUF421)
LKAIADJA_00317 4.1e-18 ykzE
LKAIADJA_00318 1.6e-188 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
LKAIADJA_00319 0.0 kinE 2.7.13.3 T Histidine kinase
LKAIADJA_00320 1.3e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LKAIADJA_00322 8.2e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LKAIADJA_00323 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
LKAIADJA_00324 3.3e-149 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LKAIADJA_00325 3.4e-230 mtnE 2.6.1.83 E Aminotransferase
LKAIADJA_00326 3.4e-230 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
LKAIADJA_00327 3.2e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
LKAIADJA_00328 8e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
LKAIADJA_00329 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LKAIADJA_00330 5.4e-50 XK27_09985 S Protein of unknown function (DUF1232)
LKAIADJA_00331 6.4e-09 S Spo0E like sporulation regulatory protein
LKAIADJA_00332 9.5e-53 eag
LKAIADJA_00333 5.8e-29 S Protein of unknown function (DUF1657)
LKAIADJA_00334 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
LKAIADJA_00335 1.7e-249 ywaD 3.4.11.10, 3.4.11.6 S PA domain
LKAIADJA_00336 1.9e-158 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LKAIADJA_00337 2.6e-10 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LKAIADJA_00338 4e-87 ywaE K Transcriptional regulator
LKAIADJA_00339 2.4e-40 ywaF S Integral membrane protein
LKAIADJA_00340 1.9e-166 gspA M General stress
LKAIADJA_00341 4e-153 sacY K transcriptional antiterminator
LKAIADJA_00342 4.4e-242 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LKAIADJA_00343 2.1e-134 epr 3.4.21.62 O Belongs to the peptidase S8 family
LKAIADJA_00344 1.6e-61 epr 3.4.21.62 O Belongs to the peptidase S8 family
LKAIADJA_00345 9.5e-242 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LKAIADJA_00346 4.4e-67 ywbC 4.4.1.5 E glyoxalase
LKAIADJA_00347 4.5e-219 ywbD 2.1.1.191 J Methyltransferase
LKAIADJA_00348 2.3e-27 ywbE S Uncharacterized conserved protein (DUF2196)
LKAIADJA_00349 4.2e-68 ywbF EGP Major facilitator Superfamily
LKAIADJA_00350 1.2e-122 ywbF EGP Major facilitator Superfamily
LKAIADJA_00351 6.8e-111 ywbG M effector of murein hydrolase
LKAIADJA_00352 1.9e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
LKAIADJA_00353 4.3e-153 ywbI K Transcriptional regulator
LKAIADJA_00354 1.2e-141 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LKAIADJA_00355 2.5e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
LKAIADJA_00356 2.3e-249 P COG0672 High-affinity Fe2 Pb2 permease
LKAIADJA_00357 7.9e-184 ycdO P periplasmic lipoprotein involved in iron transport
LKAIADJA_00358 2.5e-223 ywbN P Dyp-type peroxidase family protein
LKAIADJA_00359 2.4e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
LKAIADJA_00360 2.6e-267 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LKAIADJA_00361 6.4e-48 ywcB S Protein of unknown function, DUF485
LKAIADJA_00363 4.7e-120 ywcC K transcriptional regulator
LKAIADJA_00364 9.5e-60 gtcA S GtrA-like protein
LKAIADJA_00365 3.4e-302 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
LKAIADJA_00366 1e-35 ywzA S membrane
LKAIADJA_00367 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
LKAIADJA_00368 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LKAIADJA_00369 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
LKAIADJA_00370 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
LKAIADJA_00371 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
LKAIADJA_00372 8.6e-202 rodA D Belongs to the SEDS family
LKAIADJA_00373 6.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
LKAIADJA_00374 9.5e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LKAIADJA_00375 0.0 vpr O Belongs to the peptidase S8 family
LKAIADJA_00378 1e-148 sacT K transcriptional antiterminator
LKAIADJA_00379 3.3e-138 focA P Formate/nitrite transporter
LKAIADJA_00380 1.2e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LKAIADJA_00381 2.1e-287 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
LKAIADJA_00382 2e-28 ywdA
LKAIADJA_00383 3e-145 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
LKAIADJA_00384 8.2e-57 pex K Transcriptional regulator PadR-like family
LKAIADJA_00385 3.4e-112 ywdD
LKAIADJA_00387 7.2e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
LKAIADJA_00388 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LKAIADJA_00389 5e-262 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
LKAIADJA_00390 7.7e-49 ywdI S Family of unknown function (DUF5327)
LKAIADJA_00391 3.7e-238 ywdJ F Xanthine uracil
LKAIADJA_00392 4.3e-59 ywdK S small membrane protein
LKAIADJA_00393 1.7e-72 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
LKAIADJA_00394 1.8e-144 spsA M Spore Coat
LKAIADJA_00395 8.9e-267 spsB M Capsule polysaccharide biosynthesis protein
LKAIADJA_00396 2.5e-222 spsC E Belongs to the DegT DnrJ EryC1 family
LKAIADJA_00397 3.7e-162 spsD 2.3.1.210 K Spore Coat
LKAIADJA_00398 2.1e-213 spsE 2.5.1.56 M acid synthase
LKAIADJA_00399 2.9e-128 spsF M Spore Coat
LKAIADJA_00400 2e-186 spsG M Spore Coat
LKAIADJA_00401 2.1e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LKAIADJA_00402 5.7e-180 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LKAIADJA_00403 2.2e-159 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LKAIADJA_00404 1.3e-86 spsL 5.1.3.13 M Spore Coat
LKAIADJA_00405 1.2e-77
LKAIADJA_00406 2.4e-203 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
LKAIADJA_00407 2.3e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
LKAIADJA_00408 0.0 rocB E arginine degradation protein
LKAIADJA_00409 5.7e-261 lysP E amino acid
LKAIADJA_00410 9.6e-204 ywfA EGP Major facilitator Superfamily
LKAIADJA_00411 4.3e-112 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
LKAIADJA_00412 1.2e-120 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
LKAIADJA_00413 5.6e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKAIADJA_00414 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
LKAIADJA_00415 1.9e-209 bacE EGP Major facilitator Superfamily
LKAIADJA_00416 5.8e-230 ywfG 2.6.1.83 E Aminotransferase class I and II
LKAIADJA_00417 1.3e-137 IQ Enoyl-(Acyl carrier protein) reductase
LKAIADJA_00418 1.1e-146 ywfI C May function as heme-dependent peroxidase
LKAIADJA_00419 6.2e-174 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
LKAIADJA_00420 9.2e-164 cysL K Transcriptional regulator
LKAIADJA_00421 1.5e-155 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
LKAIADJA_00422 5.7e-158 ywfM EG EamA-like transporter family
LKAIADJA_00423 1.8e-107 rsfA_1
LKAIADJA_00424 3.1e-36 ywzC S Belongs to the UPF0741 family
LKAIADJA_00425 1.9e-255 ywfO S COG1078 HD superfamily phosphohydrolases
LKAIADJA_00426 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
LKAIADJA_00427 6.2e-79 yffB K Transcriptional regulator
LKAIADJA_00428 9.2e-235 mmr U Major Facilitator Superfamily
LKAIADJA_00430 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LKAIADJA_00431 4.7e-70 ywhA K Transcriptional regulator
LKAIADJA_00432 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
LKAIADJA_00433 5.1e-119 ywhC S Peptidase family M50
LKAIADJA_00434 2e-94 ywhD S YwhD family
LKAIADJA_00435 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LKAIADJA_00436 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LKAIADJA_00437 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
LKAIADJA_00439 7.5e-86 S aspartate phosphatase
LKAIADJA_00440 8.9e-187 ywhK CO amine dehydrogenase activity
LKAIADJA_00441 1.2e-242 ywhL CO amine dehydrogenase activity
LKAIADJA_00443 8e-246 L Peptidase, M16
LKAIADJA_00444 1.2e-214 2.7.1.26, 2.7.7.2 L Peptidase, M16
LKAIADJA_00445 1.6e-233 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
LKAIADJA_00446 1.3e-131 cbiO V ABC transporter
LKAIADJA_00447 4.9e-270 C Fe-S oxidoreductases
LKAIADJA_00448 1e-07 S Bacteriocin subtilosin A
LKAIADJA_00449 4.7e-73 ywiB S protein conserved in bacteria
LKAIADJA_00450 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
LKAIADJA_00451 3.9e-213 narK P COG2223 Nitrate nitrite transporter
LKAIADJA_00452 2e-129 fnr K helix_turn_helix, cAMP Regulatory protein
LKAIADJA_00453 1.7e-139 ywiC S YwiC-like protein
LKAIADJA_00454 7e-86 arfM T cyclic nucleotide binding
LKAIADJA_00455 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LKAIADJA_00456 1.9e-296 narH 1.7.5.1 C Nitrate reductase, beta
LKAIADJA_00457 1.6e-94 narJ 1.7.5.1 C nitrate reductase
LKAIADJA_00458 3.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
LKAIADJA_00459 7.9e-285 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LKAIADJA_00460 0.0 ywjA V ABC transporter
LKAIADJA_00461 5.9e-94 ywjB H RibD C-terminal domain
LKAIADJA_00462 2.7e-42 ywjC
LKAIADJA_00463 2.5e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
LKAIADJA_00464 1.1e-212 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
LKAIADJA_00465 0.0 fadF C COG0247 Fe-S oxidoreductase
LKAIADJA_00466 1.4e-209 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
LKAIADJA_00467 1.4e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LKAIADJA_00468 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LKAIADJA_00470 2.2e-117 S Protein of unknwon function (DUF3310)
LKAIADJA_00471 7.7e-32
LKAIADJA_00472 1.6e-51
LKAIADJA_00474 1.1e-39 S VRR_NUC
LKAIADJA_00475 0.0 S D5 N terminal like
LKAIADJA_00476 3.7e-73 S Protein of unknown function (DUF669)
LKAIADJA_00477 2.6e-205 res L helicase
LKAIADJA_00479 7.8e-94 S AAA domain
LKAIADJA_00480 8.9e-23 S Hypothetical protein of unknown function (DUF2483)
LKAIADJA_00483 5.2e-30
LKAIADJA_00484 2e-10 K DNA-binding helix-turn-helix protein
LKAIADJA_00485 4.8e-28 K Cro/C1-type HTH DNA-binding domain
LKAIADJA_00486 6.4e-44 E Pfam:DUF955
LKAIADJA_00488 1.7e-201 int L Arm DNA-binding domain
LKAIADJA_00489 4.8e-268 sufB O assembly protein SufB
LKAIADJA_00490 4.3e-77 nifU C NifU homolog involved in Fe-S cluster formation
LKAIADJA_00491 1.2e-214 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LKAIADJA_00492 8.8e-240 sufD O assembly protein SufD
LKAIADJA_00493 6.6e-139 sufC O FeS assembly ATPase SufC
LKAIADJA_00494 6.3e-130 S Domain of unknown function (DUF368)
LKAIADJA_00495 5.1e-129 metQ M Belongs to the nlpA lipoprotein family
LKAIADJA_00496 3e-85 metI P ABC transporter permease
LKAIADJA_00497 8.5e-182 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LKAIADJA_00498 2.8e-48 yusE CO Thioredoxin
LKAIADJA_00499 1.2e-64 rnmV 3.1.26.8 L TOPRIM
LKAIADJA_00500 6.6e-63 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
LKAIADJA_00501 1.7e-60 arsC 1.20.4.1 P Belongs to the ArsC family
LKAIADJA_00502 1.9e-55 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
LKAIADJA_00503 1.2e-97 ydjA C nitroreductase
LKAIADJA_00504 3.8e-112 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
LKAIADJA_00505 7.9e-73 ohr O response to oxidative stress
LKAIADJA_00506 1.6e-83 2.3.1.178, 2.3.1.57, 2.3.1.82 J Acetyltransferase (GNAT) domain
LKAIADJA_00507 5.9e-34
LKAIADJA_00508 1.5e-228 citH C Citrate transporter
LKAIADJA_00509 1.1e-31
LKAIADJA_00510 9.3e-30 S Belongs to the UPF0346 family
LKAIADJA_00511 1.8e-30 S TM2 domain
LKAIADJA_00512 4.2e-15
LKAIADJA_00513 8.2e-15
LKAIADJA_00514 1.6e-33
LKAIADJA_00515 9.4e-12
LKAIADJA_00516 1.6e-142 P Sodium Bile acid symporter family
LKAIADJA_00517 1.2e-22
LKAIADJA_00518 6e-21
LKAIADJA_00519 3.7e-61 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LKAIADJA_00520 7.6e-18 K sequence-specific DNA binding
LKAIADJA_00521 1e-21
LKAIADJA_00522 2.6e-133 pldB 3.1.1.5 I alpha/beta hydrolase fold
LKAIADJA_00523 7.9e-42
LKAIADJA_00524 6.7e-217 S C4-dicarboxylate anaerobic carrier
LKAIADJA_00525 2.3e-73 yycN 2.3.1.128 K FR47-like protein
LKAIADJA_00526 0.0 3.6.3.4 P P-type ATPase
LKAIADJA_00527 5.3e-57 glxI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LKAIADJA_00528 9e-47 EGP Major facilitator Superfamily
LKAIADJA_00529 1.9e-81 E GDSL-like Lipase/Acylhydrolase family
LKAIADJA_00530 1.7e-09 E GDSL-like Lipase/Acylhydrolase family
LKAIADJA_00531 9.1e-30
LKAIADJA_00533 1.7e-23
LKAIADJA_00534 1.4e-47 yczJ S Antibiotic biosynthesis monooxygenase
LKAIADJA_00535 4.8e-28
LKAIADJA_00536 1e-72 J Acetyltransferase (GNAT) domain
LKAIADJA_00537 1.4e-69 fosB 2.5.1.18 E Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
LKAIADJA_00538 1.6e-79 yycN 2.3.1.128 K FR47-like protein
LKAIADJA_00542 4.8e-49
LKAIADJA_00543 2e-49
LKAIADJA_00544 1.5e-89 M sporulation resulting in formation of a cellular spore
LKAIADJA_00545 2.8e-77 terS L phage terminase small subunit
LKAIADJA_00546 2e-12 S Protein of unknown function (DUF3102)
LKAIADJA_00547 2.1e-76
LKAIADJA_00548 1.5e-91
LKAIADJA_00549 2.6e-26
LKAIADJA_00550 9.9e-147 S Virulence-associated protein E
LKAIADJA_00551 1.8e-159 S Primase C terminal 1 (PriCT-1)
LKAIADJA_00552 1.4e-39
LKAIADJA_00553 5.9e-49
LKAIADJA_00554 6.1e-07 S serine-type endopeptidase activity
LKAIADJA_00556 8.6e-23 K Helix-turn-helix XRE-family like proteins
LKAIADJA_00557 3.1e-58 K Helix-turn-helix XRE-family like proteins
LKAIADJA_00558 7.3e-187 L Phage integrase family
LKAIADJA_00559 9.6e-115
LKAIADJA_00561 7.3e-80 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LKAIADJA_00562 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LKAIADJA_00563 1.3e-136 est 3.1.1.1 S Carboxylesterase
LKAIADJA_00564 8.3e-32 secG U Preprotein translocase subunit SecG
LKAIADJA_00565 1.3e-73
LKAIADJA_00566 2.6e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LKAIADJA_00567 1.3e-290 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LKAIADJA_00568 8.7e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LKAIADJA_00569 1.2e-216 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
LKAIADJA_00570 1.1e-186 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LKAIADJA_00571 3.4e-186 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LKAIADJA_00572 1.8e-31
LKAIADJA_00573 3.8e-18 S Domain of unknown function (DUF4887)
LKAIADJA_00575 6.8e-167 yfhF S epimerase dehydratase family
LKAIADJA_00577 5.5e-101 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LKAIADJA_00579 6.1e-125 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LKAIADJA_00580 8.7e-165 whiA K May be required for sporulation
LKAIADJA_00581 5.7e-175 ybhK S Required for morphogenesis under gluconeogenic growth conditions
LKAIADJA_00582 5.2e-170 rapZ S Displays ATPase and GTPase activities
LKAIADJA_00583 7.9e-174 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LKAIADJA_00584 1.4e-267 S Tetratricopeptide repeat
LKAIADJA_00585 3.4e-64 yvoF S Hexapeptide repeat of succinyl-transferase
LKAIADJA_00586 5.2e-153 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LKAIADJA_00587 9.9e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LKAIADJA_00588 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LKAIADJA_00589 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LKAIADJA_00590 1.2e-30 csbA S Uncharacterized protein conserved in bacteria (DUF2198)
LKAIADJA_00591 2.1e-117 yfbR S HD containing hydrolase-like enzyme
LKAIADJA_00592 1.3e-141 M CHAP domain
LKAIADJA_00593 3.3e-186 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LKAIADJA_00594 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LKAIADJA_00595 7e-77 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LKAIADJA_00596 1.9e-65 comFC S Competence protein
LKAIADJA_00597 1.6e-217 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LKAIADJA_00598 2.3e-151 degV S Uncharacterised protein, DegV family COG1307
LKAIADJA_00599 3.8e-111 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
LKAIADJA_00600 1.2e-154 tagO 2.7.8.33, 2.7.8.35 M transferase
LKAIADJA_00601 8.9e-182 yliF T signal transduction by protein phosphorylation
LKAIADJA_00602 6e-124 thrE S Putative threonine/serine exporter
LKAIADJA_00603 2.4e-84 S Putative threonine/serine exporter
LKAIADJA_00604 8.6e-229 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
LKAIADJA_00605 7.6e-192 garK 2.7.1.165 G Glycerate kinase
LKAIADJA_00606 2.8e-54 ytxJ O Protein of unknown function (DUF2847)
LKAIADJA_00607 1.3e-101
LKAIADJA_00608 3.8e-88 S GrpB protein
LKAIADJA_00609 5.2e-170 murB 1.3.1.98 M Cell wall formation
LKAIADJA_00610 3.2e-47 S CHY zinc finger
LKAIADJA_00611 1.2e-55 S Bacterial PH domain
LKAIADJA_00612 2e-149 fatB P COG4607 ABC-type enterochelin transport system, periplasmic component
LKAIADJA_00613 3.5e-138 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
LKAIADJA_00614 2.6e-148 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKAIADJA_00615 2e-164 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKAIADJA_00616 1.1e-183 nrdF 1.17.4.1 F reductase, beta subunit
LKAIADJA_00617 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LKAIADJA_00618 1.3e-61 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
LKAIADJA_00619 1.7e-149 EG of the drug metabolite transporter (DMT) superfamily
LKAIADJA_00620 1e-95 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LKAIADJA_00621 4.4e-251 dtpT E transporter
LKAIADJA_00622 2e-267 dtpT E transporter
LKAIADJA_00623 1.9e-175 yegS I Diacylglycerol kinase catalytic domain
LKAIADJA_00626 5.3e-27 spoVAE S stage V sporulation protein
LKAIADJA_00628 7.8e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LKAIADJA_00629 6.8e-103 T Domain of unknown function (DUF4163)
LKAIADJA_00630 3e-47 yxiS
LKAIADJA_00631 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
LKAIADJA_00632 6.6e-224 citH C Citrate transporter
LKAIADJA_00633 6.6e-83 exoK GH16 M licheninase activity
LKAIADJA_00634 2.1e-51 exoK GH16 M licheninase activity
LKAIADJA_00635 2.3e-139 licT K transcriptional antiterminator
LKAIADJA_00636 1.2e-110
LKAIADJA_00637 2.3e-229 yxiO S COG2270 Permeases of the major facilitator superfamily
LKAIADJA_00638 4.3e-264 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
LKAIADJA_00639 3.5e-208 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
LKAIADJA_00642 5.7e-46 yxiJ S YxiJ-like protein
LKAIADJA_00643 1.6e-93 yxiI S Protein of unknown function (DUF2716)
LKAIADJA_00644 2e-139
LKAIADJA_00645 3.7e-75 yxiG
LKAIADJA_00646 6.4e-63
LKAIADJA_00647 4.9e-84
LKAIADJA_00648 1.5e-71 yxxG
LKAIADJA_00649 0.0 wapA M COG3209 Rhs family protein
LKAIADJA_00650 1.5e-164 yxxF EG EamA-like transporter family
LKAIADJA_00651 4.5e-71 yxiE T Belongs to the universal stress protein A family
LKAIADJA_00652 2.8e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LKAIADJA_00653 3.1e-296 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LKAIADJA_00654 5.5e-53
LKAIADJA_00655 5.2e-210 S nuclease activity
LKAIADJA_00656 4.7e-39 yxiC S Family of unknown function (DUF5344)
LKAIADJA_00657 1e-20 S Domain of unknown function (DUF5082)
LKAIADJA_00658 1.4e-42 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
LKAIADJA_00659 1e-53 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
LKAIADJA_00660 3.6e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
LKAIADJA_00661 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LKAIADJA_00662 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LKAIADJA_00663 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LKAIADJA_00664 1.8e-116 yxxB S Domain of Unknown Function (DUF1206)
LKAIADJA_00665 2.4e-150 yxxB S Domain of Unknown Function (DUF1206)
LKAIADJA_00666 4.1e-198 eutH E Ethanolamine utilisation protein, EutH
LKAIADJA_00667 8.6e-251 yxeQ S MmgE/PrpD family
LKAIADJA_00668 4.7e-213 yxeP 3.5.1.47 E hydrolase activity
LKAIADJA_00669 1.7e-131 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
LKAIADJA_00670 2.7e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
LKAIADJA_00671 4.6e-143 yxeM M Belongs to the bacterial solute-binding protein 3 family
LKAIADJA_00672 8.9e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LKAIADJA_00673 2.2e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LKAIADJA_00674 5.9e-188 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
LKAIADJA_00675 6.2e-151 yidA S hydrolases of the HAD superfamily
LKAIADJA_00678 1.3e-20 yxeE
LKAIADJA_00679 1.9e-16 yxeD
LKAIADJA_00680 8.5e-69
LKAIADJA_00681 2.3e-176 fhuD P ABC transporter
LKAIADJA_00682 1.5e-58 yxeA S Protein of unknown function (DUF1093)
LKAIADJA_00683 0.0 yxdM V ABC transporter (permease)
LKAIADJA_00684 9.7e-138 yxdL V ABC transporter, ATP-binding protein
LKAIADJA_00685 1.2e-177 T PhoQ Sensor
LKAIADJA_00686 4.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKAIADJA_00687 4.6e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
LKAIADJA_00688 8e-146 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
LKAIADJA_00689 3.3e-166 iolH G Xylose isomerase-like TIM barrel
LKAIADJA_00690 2.3e-195 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
LKAIADJA_00691 6.2e-233 iolF EGP Major facilitator Superfamily
LKAIADJA_00692 4.7e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
LKAIADJA_00693 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
LKAIADJA_00694 2.5e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
LKAIADJA_00695 2.3e-153 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
LKAIADJA_00696 3e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LKAIADJA_00697 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
LKAIADJA_00698 1.9e-175 iolS C Aldo keto reductase
LKAIADJA_00700 1.9e-47 yxcD S Protein of unknown function (DUF2653)
LKAIADJA_00701 3.6e-244 csbC EGP Major facilitator Superfamily
LKAIADJA_00702 0.0 htpG O Molecular chaperone. Has ATPase activity
LKAIADJA_00704 2.6e-18 IQ Enoyl-(Acyl carrier protein) reductase
LKAIADJA_00705 1.2e-208 yxbF K Bacterial regulatory proteins, tetR family
LKAIADJA_00706 1.9e-245 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
LKAIADJA_00707 4.5e-29 yxaI S membrane protein domain
LKAIADJA_00708 9.9e-92 S PQQ-like domain
LKAIADJA_00709 1.8e-64 S Family of unknown function (DUF5391)
LKAIADJA_00710 6.9e-75 yxaI S membrane protein domain
LKAIADJA_00711 2.8e-224 P Protein of unknown function (DUF418)
LKAIADJA_00712 6.4e-198 yxaG 1.13.11.24 S AraC-like ligand binding domain
LKAIADJA_00713 7.1e-101 yxaF K Transcriptional regulator
LKAIADJA_00714 1e-198 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LKAIADJA_00715 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
LKAIADJA_00716 8.9e-50 S LrgA family
LKAIADJA_00717 2.6e-118 yxaC M effector of murein hydrolase
LKAIADJA_00718 3.7e-193 yxaB GM Polysaccharide pyruvyl transferase
LKAIADJA_00719 2.1e-205 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
LKAIADJA_00720 7.3e-127 gntR K transcriptional
LKAIADJA_00721 1.5e-302 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
LKAIADJA_00722 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
LKAIADJA_00723 4.3e-269 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LKAIADJA_00724 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
LKAIADJA_00725 3.8e-287 ahpF O Alkyl hydroperoxide reductase
LKAIADJA_00726 2e-290 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LKAIADJA_00727 2.4e-19 bglF G phosphotransferase system
LKAIADJA_00728 1.3e-128 yydK K Transcriptional regulator
LKAIADJA_00729 7.6e-13
LKAIADJA_00730 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
LKAIADJA_00731 2e-52 L EcoRII C terminal
LKAIADJA_00732 2.2e-176 nlaXM 2.1.1.37 H C-5 cytosine-specific DNA methylase
LKAIADJA_00733 1.8e-45 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
LKAIADJA_00735 2.4e-25 I PLD-like domain
LKAIADJA_00737 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LKAIADJA_00738 1.1e-09 S YyzF-like protein
LKAIADJA_00739 8.8e-31
LKAIADJA_00740 6.7e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LKAIADJA_00742 8.2e-30 yycQ S Protein of unknown function (DUF2651)
LKAIADJA_00743 1.2e-208 yycP
LKAIADJA_00744 3.8e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
LKAIADJA_00745 8.4e-84 yycN 2.3.1.128 K Acetyltransferase
LKAIADJA_00746 5e-188 S aspartate phosphatase
LKAIADJA_00748 2e-166 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
LKAIADJA_00749 2.8e-260 rocE E amino acid
LKAIADJA_00750 2.6e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
LKAIADJA_00751 3.4e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
LKAIADJA_00752 1.3e-216 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LKAIADJA_00753 7.4e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
LKAIADJA_00754 3.6e-154 yycI S protein conserved in bacteria
LKAIADJA_00755 4.4e-258 yycH S protein conserved in bacteria
LKAIADJA_00756 0.0 vicK 2.7.13.3 T Histidine kinase
LKAIADJA_00757 1.5e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKAIADJA_00760 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
LKAIADJA_00761 3e-238 3.2.1.11 GH66 G Glycosyl hydrolase family 66
LKAIADJA_00762 7.7e-80 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LKAIADJA_00763 1e-153 yusV 3.6.3.34 HP ABC transporter
LKAIADJA_00764 1.9e-66 S YusW-like protein
LKAIADJA_00765 7.9e-300 pepF2 E COG1164 Oligoendopeptidase F
LKAIADJA_00766 2e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LKAIADJA_00767 2.7e-79 dps P Ferritin-like domain
LKAIADJA_00768 4.4e-234 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LKAIADJA_00769 5.7e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKAIADJA_00770 9.7e-250 cssS 2.7.13.3 T PhoQ Sensor
LKAIADJA_00771 1.3e-157 yuxN K Transcriptional regulator
LKAIADJA_00772 5.6e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LKAIADJA_00773 3.9e-24 S Protein of unknown function (DUF3970)
LKAIADJA_00774 1.1e-240 gerAA EG Spore germination protein
LKAIADJA_00775 1.1e-195 gerAB E Spore germination protein
LKAIADJA_00776 2.8e-178 gerAC S Spore germination B3/ GerAC like, C-terminal
LKAIADJA_00777 8.1e-106 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LKAIADJA_00778 1.6e-186 vraS 2.7.13.3 T Histidine kinase
LKAIADJA_00779 9.5e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
LKAIADJA_00780 3.1e-116 liaG S Putative adhesin
LKAIADJA_00781 3.6e-104 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
LKAIADJA_00782 7.3e-62 liaI S membrane
LKAIADJA_00783 5.9e-225 yvqJ EGP Major facilitator Superfamily
LKAIADJA_00784 3.9e-99 yvqK 2.5.1.17 S Adenosyltransferase
LKAIADJA_00785 2.1e-244 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
LKAIADJA_00786 1.9e-184 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKAIADJA_00787 2.6e-169 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
LKAIADJA_00788 1.5e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LKAIADJA_00789 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
LKAIADJA_00790 0.0 T PhoQ Sensor
LKAIADJA_00791 1.2e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKAIADJA_00792 3.6e-22
LKAIADJA_00793 2.3e-96 yvrI K RNA polymerase
LKAIADJA_00794 2.4e-19 S YvrJ protein family
LKAIADJA_00795 2.3e-228 oxdC 4.1.1.2 G Oxalate decarboxylase
LKAIADJA_00796 3.2e-63 yvrL S Regulatory protein YrvL
LKAIADJA_00797 1.5e-209 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
LKAIADJA_00798 1.6e-123 macB V ABC transporter, ATP-binding protein
LKAIADJA_00799 5.8e-174 M Efflux transporter rnd family, mfp subunit
LKAIADJA_00800 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
LKAIADJA_00801 2.5e-173 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKAIADJA_00802 9.6e-181 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKAIADJA_00803 2.6e-177 fhuD P ABC transporter
LKAIADJA_00804 4.9e-236 yvsH E Arginine ornithine antiporter
LKAIADJA_00805 6.5e-16 S Small spore protein J (Spore_SspJ)
LKAIADJA_00806 2.3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
LKAIADJA_00807 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
LKAIADJA_00808 2.3e-165 yvgK P COG1910 Periplasmic molybdate-binding protein domain
LKAIADJA_00809 1.2e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
LKAIADJA_00810 2.4e-119 modB P COG4149 ABC-type molybdate transport system, permease component
LKAIADJA_00811 9.4e-155 yvgN S reductase
LKAIADJA_00812 5.4e-86 yvgO
LKAIADJA_00813 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
LKAIADJA_00814 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
LKAIADJA_00815 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LKAIADJA_00816 0.0 helD 3.6.4.12 L DNA helicase
LKAIADJA_00817 4.1e-107 yvgT S membrane
LKAIADJA_00818 8.5e-72 bdbC O Required for disulfide bond formation in some proteins
LKAIADJA_00819 1.6e-104 bdbD O Thioredoxin
LKAIADJA_00820 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
LKAIADJA_00821 0.0 copA 3.6.3.54 P P-type ATPase
LKAIADJA_00822 5.9e-29 copZ P Copper resistance protein CopZ
LKAIADJA_00823 2.2e-48 csoR S transcriptional
LKAIADJA_00824 6.4e-193 yvaA 1.1.1.371 S Oxidoreductase
LKAIADJA_00825 1.6e-117 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LKAIADJA_00826 1e-105 yvaC S Fusaric acid resistance protein-like
LKAIADJA_00827 7.9e-217 yvaC S Fusaric acid resistance protein-like
LKAIADJA_00828 5.7e-73 yvaD S Family of unknown function (DUF5360)
LKAIADJA_00829 6.9e-54 yvaE P Small Multidrug Resistance protein
LKAIADJA_00830 2.1e-94 K Bacterial regulatory proteins, tetR family
LKAIADJA_00831 4.2e-87 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LKAIADJA_00832 2.2e-14 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LKAIADJA_00834 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LKAIADJA_00835 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LKAIADJA_00836 9.6e-143 est 3.1.1.1 S Carboxylesterase
LKAIADJA_00837 2.4e-23 secG U Preprotein translocase subunit SecG
LKAIADJA_00838 3.4e-151 yvaM S Serine aminopeptidase, S33
LKAIADJA_00839 9.8e-36 yvzC K Transcriptional
LKAIADJA_00840 2.6e-68 K transcriptional
LKAIADJA_00841 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
LKAIADJA_00842 2.2e-54 yodB K transcriptional
LKAIADJA_00843 1.2e-19 NT chemotaxis protein
LKAIADJA_00844 2.2e-170 NT chemotaxis protein
LKAIADJA_00845 1.5e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
LKAIADJA_00846 4.2e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LKAIADJA_00847 1.6e-109 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
LKAIADJA_00848 9.2e-209 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
LKAIADJA_00849 7.4e-60 yvbF K Belongs to the GbsR family
LKAIADJA_00850 7.9e-13 S Sporulation delaying protein SdpA
LKAIADJA_00851 4.9e-171
LKAIADJA_00852 4.4e-08
LKAIADJA_00853 3.3e-96 sdpI S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
LKAIADJA_00854 4.5e-45 sdpR K transcriptional
LKAIADJA_00855 8.7e-114 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
LKAIADJA_00856 7.9e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LKAIADJA_00857 1.2e-104 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
LKAIADJA_00858 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
LKAIADJA_00859 3.5e-97 yvbF K Belongs to the GbsR family
LKAIADJA_00860 6e-101 yvbG U UPF0056 membrane protein
LKAIADJA_00861 1.9e-112 yvbH S YvbH-like oligomerisation region
LKAIADJA_00862 2.2e-120 exoY M Membrane
LKAIADJA_00863 8.1e-252 tcaA S response to antibiotic
LKAIADJA_00864 8.3e-76 yvbK 3.1.3.25 K acetyltransferase
LKAIADJA_00865 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LKAIADJA_00866 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
LKAIADJA_00867 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LKAIADJA_00868 1.6e-216 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
LKAIADJA_00869 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LKAIADJA_00870 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LKAIADJA_00871 1.6e-252 araE EGP Major facilitator Superfamily
LKAIADJA_00872 5.5e-203 araR K transcriptional
LKAIADJA_00873 5.8e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LKAIADJA_00874 9.6e-158 yvbU K Transcriptional regulator
LKAIADJA_00875 1.2e-155 yvbV EG EamA-like transporter family
LKAIADJA_00877 2.9e-38 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LKAIADJA_00878 5.7e-33 yvkN
LKAIADJA_00879 8e-49 yvlA
LKAIADJA_00880 9.2e-166 yvlB S Putative adhesin
LKAIADJA_00881 2.6e-26 pspB KT PspC domain
LKAIADJA_00882 1.2e-50 yvlD S Membrane
LKAIADJA_00883 2.7e-203 yvmA EGP Major facilitator Superfamily
LKAIADJA_00884 7.4e-86 yvmB K helix_turn_helix multiple antibiotic resistance protein
LKAIADJA_00885 1.8e-136 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
LKAIADJA_00886 4.1e-231 cypX 1.14.15.13 C Cytochrome P450
LKAIADJA_00887 4.2e-83 adcR K helix_turn_helix multiple antibiotic resistance protein
LKAIADJA_00888 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
LKAIADJA_00889 3.6e-134 yvoA K transcriptional
LKAIADJA_00890 1e-128 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LKAIADJA_00891 8.6e-218 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
LKAIADJA_00892 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LKAIADJA_00893 1.2e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LKAIADJA_00894 1.6e-163 yvoD P COG0370 Fe2 transport system protein B
LKAIADJA_00895 3.2e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
LKAIADJA_00896 1.6e-80 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
LKAIADJA_00897 8.7e-119 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
LKAIADJA_00898 1.1e-138 yvpB NU protein conserved in bacteria
LKAIADJA_00899 2.4e-220 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LKAIADJA_00900 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
LKAIADJA_00901 1.5e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LKAIADJA_00902 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
LKAIADJA_00903 1.1e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LKAIADJA_00904 1.1e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LKAIADJA_00905 1.4e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
LKAIADJA_00906 8.8e-113 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
LKAIADJA_00907 1.6e-118
LKAIADJA_00908 0.0
LKAIADJA_00910 0.0 msbA2 3.6.3.44 V ABC transporter
LKAIADJA_00911 5e-276 S COG0457 FOG TPR repeat
LKAIADJA_00912 1.1e-97 usp CBM50 M protein conserved in bacteria
LKAIADJA_00913 9.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LKAIADJA_00914 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
LKAIADJA_00915 5.7e-166 rapZ S Displays ATPase and GTPase activities
LKAIADJA_00916 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
LKAIADJA_00917 1.4e-170 whiA K May be required for sporulation
LKAIADJA_00918 1.6e-36 crh G Phosphocarrier protein Chr
LKAIADJA_00919 4.9e-142 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
LKAIADJA_00920 3.3e-32
LKAIADJA_00921 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKAIADJA_00922 1.3e-196 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
LKAIADJA_00923 2.1e-140 yvcR V ABC transporter, ATP-binding protein
LKAIADJA_00924 0.0 yxdM V ABC transporter (permease)
LKAIADJA_00925 8.7e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LKAIADJA_00926 3.1e-104 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
LKAIADJA_00927 1.1e-287 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
LKAIADJA_00928 1.5e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
LKAIADJA_00929 1.6e-105 yvdD 3.2.2.10 S Belongs to the LOG family
LKAIADJA_00930 3.3e-172 yvdE K Transcriptional regulator
LKAIADJA_00931 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
LKAIADJA_00932 2.4e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
LKAIADJA_00933 4.5e-244 malC P COG1175 ABC-type sugar transport systems, permease components
LKAIADJA_00934 3.9e-148 malD P transport
LKAIADJA_00935 3.2e-153 malA S Protein of unknown function (DUF1189)
LKAIADJA_00936 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
LKAIADJA_00937 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
LKAIADJA_00938 1.3e-114 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
LKAIADJA_00939 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LKAIADJA_00941 1.3e-72 yvdQ S Protein of unknown function (DUF3231)
LKAIADJA_00942 7.1e-50 sugE P Small Multidrug Resistance protein
LKAIADJA_00943 1.6e-49 ykkC P Small Multidrug Resistance protein
LKAIADJA_00944 7.4e-106 yvdT K Transcriptional regulator
LKAIADJA_00945 1.8e-295 yveA E amino acid
LKAIADJA_00946 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
LKAIADJA_00947 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
LKAIADJA_00948 9e-264 pbpE V Beta-lactamase
LKAIADJA_00949 3e-122 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
LKAIADJA_00950 1.3e-73 MA20_18690 S Protein of unknown function (DUF3237)
LKAIADJA_00951 1.7e-92 padC Q Phenolic acid decarboxylase
LKAIADJA_00953 1.4e-281 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
LKAIADJA_00954 1.4e-75 slr K transcriptional
LKAIADJA_00955 8.9e-122 ywqC M biosynthesis protein
LKAIADJA_00956 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
LKAIADJA_00957 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
LKAIADJA_00958 1.1e-222 epsD GT4 M Glycosyl transferase 4-like
LKAIADJA_00959 1.6e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LKAIADJA_00960 6.4e-218 epsF GT4 M Glycosyl transferases group 1
LKAIADJA_00961 2.4e-206 epsG S EpsG family
LKAIADJA_00962 2e-194 epsH GT2 S Glycosyltransferase like family 2
LKAIADJA_00963 1.1e-200 epsI GM pyruvyl transferase
LKAIADJA_00964 1.2e-191 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
LKAIADJA_00965 3.1e-257 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LKAIADJA_00966 2.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
LKAIADJA_00967 6.6e-55 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
LKAIADJA_00968 6.9e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
LKAIADJA_00969 3.7e-187 yvfF GM Exopolysaccharide biosynthesis protein
LKAIADJA_00970 1e-31 yvfG S YvfG protein
LKAIADJA_00971 8.8e-240 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
LKAIADJA_00972 7.5e-308 yvfH C L-lactate permease
LKAIADJA_00973 2.7e-113 yvfI K COG2186 Transcriptional regulators
LKAIADJA_00974 1.8e-184 lacR K Transcriptional regulator
LKAIADJA_00975 2.7e-230 cycB G COG2182 Maltose-binding periplasmic proteins domains
LKAIADJA_00976 6.5e-232 malC P COG1175 ABC-type sugar transport systems, permease components
LKAIADJA_00977 7.2e-150 ganQ P transport
LKAIADJA_00978 0.0 lacA 3.2.1.23 G beta-galactosidase
LKAIADJA_00979 1.3e-248 galA 3.2.1.89 G arabinogalactan
LKAIADJA_00980 2.7e-195 rsbU 3.1.3.3 T response regulator
LKAIADJA_00981 1.2e-152 rsbQ S Alpha/beta hydrolase family
LKAIADJA_00982 5.8e-29 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LKAIADJA_00983 6.5e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
LKAIADJA_00984 3.5e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
LKAIADJA_00985 1.5e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
LKAIADJA_00986 1.4e-195 yvbX S Glycosyl hydrolase
LKAIADJA_00987 6.2e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
LKAIADJA_00988 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LKAIADJA_00990 8.5e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LKAIADJA_00991 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LKAIADJA_00992 2.1e-36 yqfT S Protein of unknown function (DUF2624)
LKAIADJA_00993 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
LKAIADJA_00994 1.9e-77 zur P Belongs to the Fur family
LKAIADJA_00995 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
LKAIADJA_00996 3.7e-61 yqfX S membrane
LKAIADJA_00997 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LKAIADJA_00998 4.4e-46 yqfZ M LysM domain
LKAIADJA_00999 3.9e-131 yqgB S Protein of unknown function (DUF1189)
LKAIADJA_01000 4e-73 yqgC S protein conserved in bacteria
LKAIADJA_01001 3.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
LKAIADJA_01002 4e-229 yqgE EGP Major facilitator superfamily
LKAIADJA_01003 0.0 pbpA 3.4.16.4 M penicillin-binding protein
LKAIADJA_01004 3.7e-143 pstS P Phosphate
LKAIADJA_01005 9.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
LKAIADJA_01006 1.3e-157 pstA P Phosphate transport system permease
LKAIADJA_01007 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LKAIADJA_01008 1.4e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LKAIADJA_01009 7.3e-72 yqzC S YceG-like family
LKAIADJA_01010 3.5e-50 yqzD
LKAIADJA_01012 2.8e-199 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
LKAIADJA_01013 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
LKAIADJA_01014 1.4e-101 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LKAIADJA_01015 2.5e-09 yqgO
LKAIADJA_01016 4e-260 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
LKAIADJA_01017 4.7e-32 yqgQ S Protein conserved in bacteria
LKAIADJA_01018 1.5e-180 glcK 2.7.1.2 G Glucokinase
LKAIADJA_01019 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
LKAIADJA_01020 3.3e-219 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
LKAIADJA_01021 1.4e-198 yqgU
LKAIADJA_01022 6.9e-50 yqgV S Thiamine-binding protein
LKAIADJA_01023 8.9e-23 yqgW S Protein of unknown function (DUF2759)
LKAIADJA_01024 2.1e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
LKAIADJA_01025 2e-36 yqgY S Protein of unknown function (DUF2626)
LKAIADJA_01026 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
LKAIADJA_01028 1.5e-147 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LKAIADJA_01029 2.2e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
LKAIADJA_01030 6.7e-173 corA P Mg2 transporter protein
LKAIADJA_01032 5e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LKAIADJA_01033 1.4e-168 comGB NU COG1459 Type II secretory pathway, component PulF
LKAIADJA_01034 1.2e-46 comGC U Required for transformation and DNA binding
LKAIADJA_01035 4.1e-69 gspH NU protein transport across the cell outer membrane
LKAIADJA_01036 1.3e-57 comGE
LKAIADJA_01037 6e-45 comGF U Putative Competence protein ComGF
LKAIADJA_01038 2e-43 S ComG operon protein 7
LKAIADJA_01039 5.2e-26 yqzE S YqzE-like protein
LKAIADJA_01040 2.8e-53 yqzG S Protein of unknown function (DUF3889)
LKAIADJA_01041 4.8e-97 yqxM
LKAIADJA_01042 2.1e-57 sipW 3.4.21.89 U Signal peptidase
LKAIADJA_01043 4.3e-141 tasA S Cell division protein FtsN
LKAIADJA_01044 1e-54 sinR K transcriptional
LKAIADJA_01045 1.2e-24 sinI S Anti-repressor SinI
LKAIADJA_01046 1.6e-151 yqhG S Bacterial protein YqhG of unknown function
LKAIADJA_01047 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
LKAIADJA_01048 5.3e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
LKAIADJA_01049 2.2e-254 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LKAIADJA_01050 3.7e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LKAIADJA_01051 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
LKAIADJA_01052 1.3e-159 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
LKAIADJA_01053 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
LKAIADJA_01054 9e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
LKAIADJA_01055 2.8e-48 yqhP
LKAIADJA_01056 2.3e-173 yqhQ S Protein of unknown function (DUF1385)
LKAIADJA_01057 6.6e-93 yqhR S Conserved membrane protein YqhR
LKAIADJA_01058 1.6e-76 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
LKAIADJA_01059 4.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
LKAIADJA_01060 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LKAIADJA_01061 7.9e-37 yqhV S Protein of unknown function (DUF2619)
LKAIADJA_01062 4e-170 spoIIIAA S stage III sporulation protein AA
LKAIADJA_01063 1.1e-84 spoIIIAB S Stage III sporulation protein
LKAIADJA_01064 7.6e-29 spoIIIAC S stage III sporulation protein AC
LKAIADJA_01065 2.3e-58 spoIIIAD S Stage III sporulation protein AD
LKAIADJA_01066 1.3e-197 spoIIIAE S stage III sporulation protein AE
LKAIADJA_01067 1.2e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
LKAIADJA_01068 2.2e-109 spoIIIAG S stage III sporulation protein AG
LKAIADJA_01069 2.9e-90 spoIIIAH S SpoIIIAH-like protein
LKAIADJA_01070 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LKAIADJA_01071 5.9e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
LKAIADJA_01072 2.1e-67 yqhY S protein conserved in bacteria
LKAIADJA_01073 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LKAIADJA_01074 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LKAIADJA_01075 1.9e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LKAIADJA_01076 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LKAIADJA_01077 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LKAIADJA_01078 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LKAIADJA_01079 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
LKAIADJA_01080 1.7e-78 argR K Regulates arginine biosynthesis genes
LKAIADJA_01081 3.2e-306 recN L May be involved in recombinational repair of damaged DNA
LKAIADJA_01082 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
LKAIADJA_01083 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
LKAIADJA_01085 4.7e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
LKAIADJA_01086 1.5e-25
LKAIADJA_01087 8.6e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
LKAIADJA_01088 2.3e-128 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LKAIADJA_01089 1.3e-218 mmgA 2.3.1.9 I Belongs to the thiolase family
LKAIADJA_01090 2.6e-155 hbdA 1.1.1.157 I Dehydrogenase
LKAIADJA_01091 6.7e-212 mmgC I acyl-CoA dehydrogenase
LKAIADJA_01092 8.1e-210 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
LKAIADJA_01093 8.2e-276 prpD 4.2.1.79 S 2-methylcitrate dehydratase
LKAIADJA_01094 8.7e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LKAIADJA_01095 4e-34 yqzF S Protein of unknown function (DUF2627)
LKAIADJA_01096 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
LKAIADJA_01097 1e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
LKAIADJA_01098 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
LKAIADJA_01099 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
LKAIADJA_01100 1.1e-267 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LKAIADJA_01101 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LKAIADJA_01102 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LKAIADJA_01103 4.4e-228 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LKAIADJA_01104 4.4e-152 bmrR K helix_turn_helix, mercury resistance
LKAIADJA_01105 7.9e-208 norA EGP Major facilitator Superfamily
LKAIADJA_01106 3.7e-165 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LKAIADJA_01107 6e-76 yqiW S Belongs to the UPF0403 family
LKAIADJA_01108 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
LKAIADJA_01109 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
LKAIADJA_01110 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
LKAIADJA_01111 3.3e-175 yqjA S Putative aromatic acid exporter C-terminal domain
LKAIADJA_01112 1.8e-98 yqjB S protein conserved in bacteria
LKAIADJA_01113 1e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
LKAIADJA_01114 1.3e-287 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
LKAIADJA_01115 1.3e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
LKAIADJA_01116 1.7e-196 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
LKAIADJA_01119 4.6e-71 sepA U Multidrug resistance efflux pump SepA
LKAIADJA_01120 3.5e-199 mdr EGP of the major facilitator superfamily
LKAIADJA_01121 6.9e-119 yqfA S Haemolysin-III related
LKAIADJA_01122 1.5e-206 CP_1013 2.7.7.23, 2.7.7.83 G Uridylyltransferase
LKAIADJA_01123 1.8e-76 S membrane-bound metal-dependent
LKAIADJA_01124 1.9e-40
LKAIADJA_01125 2.6e-52 isdG 1.14.99.48, 1.14.99.57 C Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron
LKAIADJA_01126 5.4e-240 BH2250 S Nucleoside recognition
LKAIADJA_01127 1.5e-159 fecD P FecCD transport family
LKAIADJA_01128 1.3e-169 fhuB P FecCD transport family
LKAIADJA_01129 2.1e-180 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
LKAIADJA_01130 6.2e-135 5.1.1.12 E racemase
LKAIADJA_01131 5.4e-301 ciuE 2.7.7.7 Q siderophore
LKAIADJA_01132 2.8e-197 ciuF EGP Transmembrane secretion effector
LKAIADJA_01133 0.0 frgA Q Siderophore biosynthesis protein
LKAIADJA_01134 2e-70 asp S Alkaline shock protein 23
LKAIADJA_01135 5.7e-36 S Small integral membrane protein (DUF2273)
LKAIADJA_01136 4.4e-89 S Protein conserved in bacteria
LKAIADJA_01137 4.1e-284 opuD U Belongs to the BCCT transporter (TC 2.A.15) family
LKAIADJA_01138 3.5e-180 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
LKAIADJA_01139 2.4e-181 yfmJ 1.6.5.5 S N-terminal domain of oxidoreductase
LKAIADJA_01140 2.5e-162 C Luciferase-like monooxygenase
LKAIADJA_01141 6.3e-125 S Alpha/beta hydrolase of unknown function (DUF915)
LKAIADJA_01142 3e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
LKAIADJA_01143 8.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LKAIADJA_01144 1.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LKAIADJA_01145 3e-113 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LKAIADJA_01146 1.9e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LKAIADJA_01147 5.6e-144 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LKAIADJA_01148 2.4e-57 rplQ J Ribosomal protein L17
LKAIADJA_01149 5e-168 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LKAIADJA_01150 6.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LKAIADJA_01151 6.8e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LKAIADJA_01152 5.5e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
LKAIADJA_01153 8.3e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LKAIADJA_01154 1.4e-116 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LKAIADJA_01155 3.9e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LKAIADJA_01156 1e-59 rplO J binds to the 23S rRNA
LKAIADJA_01157 7e-23 rpmD J Ribosomal protein L30
LKAIADJA_01158 4.9e-82 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LKAIADJA_01159 1.4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LKAIADJA_01160 2.7e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LKAIADJA_01161 2.1e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LKAIADJA_01162 2.2e-27 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LKAIADJA_01163 6.7e-93 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LKAIADJA_01164 2.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LKAIADJA_01165 3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LKAIADJA_01166 2.1e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LKAIADJA_01167 1.2e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
LKAIADJA_01168 2e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LKAIADJA_01169 4e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LKAIADJA_01170 2.3e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LKAIADJA_01171 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LKAIADJA_01172 8e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LKAIADJA_01173 8e-42 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LKAIADJA_01174 1.1e-104 rplD J One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome
LKAIADJA_01175 4.3e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LKAIADJA_01176 2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
LKAIADJA_01177 1.2e-56
LKAIADJA_01178 1.9e-226 pbuG S permease
LKAIADJA_01179 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LKAIADJA_01180 2.6e-155 2.3.1.128 K (GNAT) family
LKAIADJA_01181 9.4e-150 glcU G Glucose uptake protein
LKAIADJA_01182 3.5e-143 IQ KR domain
LKAIADJA_01183 3.2e-156 XK27_04815 S Membrane transport protein
LKAIADJA_01184 5e-21
LKAIADJA_01185 4.6e-25
LKAIADJA_01186 0.0 cusA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LKAIADJA_01187 5.3e-218 femX 2.3.2.16 V Catalyzes the incorporation of amino acid(s) into the interchain peptide bridge of peptidoglycan, using aminoacyl-tRNA as amino acid donor
LKAIADJA_01188 1.3e-14
LKAIADJA_01189 2.9e-134 E Glyoxalase-like domain
LKAIADJA_01190 3.3e-66 K transcriptional
LKAIADJA_01191 2.2e-184 EGP Major facilitator Superfamily
LKAIADJA_01192 8.8e-54 sarV
LKAIADJA_01193 1.3e-193 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LKAIADJA_01194 3.8e-105 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
LKAIADJA_01195 2.4e-31 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LKAIADJA_01196 1.9e-77 moaE 2.8.1.12 H factor large subunit
LKAIADJA_01197 5.8e-80 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
LKAIADJA_01198 3.6e-222 moeA 2.10.1.1 H Molybdopterin
LKAIADJA_01199 1.2e-77 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
LKAIADJA_01200 1.5e-83 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
LKAIADJA_01201 3.1e-176 moeB 2.7.7.73, 2.7.7.80 H molybdopterin biosynthesis protein moeB
LKAIADJA_01202 1.2e-146 pqqB 3.1.4.55 S Beta-lactamase superfamily domain
LKAIADJA_01203 2.2e-105 modC 3.6.3.29 E ATP-binding protein
LKAIADJA_01204 1e-103 modB 3.6.3.29 P permease
LKAIADJA_01205 1.3e-121 modA P ABC-type molybdate transport system periplasmic component
LKAIADJA_01206 3.8e-271 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
LKAIADJA_01207 2.1e-185 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LKAIADJA_01208 4.2e-201 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LKAIADJA_01209 3.6e-172 galR K Bacterial regulatory proteins, lacI family
LKAIADJA_01210 1.3e-140 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LKAIADJA_01211 4.4e-127 K Acetyltransferase (GNAT) domain
LKAIADJA_01212 7e-82 bioY S BioY family
LKAIADJA_01213 1.4e-162 fhuD P Ferrichrome ABC transporter substrate-binding protein
LKAIADJA_01214 2.4e-251 3.5.1.28 M Ami_2
LKAIADJA_01215 3.7e-79 S Bacteriophage holin
LKAIADJA_01216 2e-41 S Domain of unknown function (DUF2479)
LKAIADJA_01217 5e-61
LKAIADJA_01218 8.7e-64
LKAIADJA_01219 7.3e-13 S Phage uncharacterised protein (Phage_XkdX)
LKAIADJA_01221 1.8e-116 S Domain of unknown function (DUF2479)
LKAIADJA_01222 3.4e-219 M Pectate lyase superfamily protein
LKAIADJA_01224 6.2e-224 S Prophage endopeptidase tail
LKAIADJA_01225 2.1e-98 S Phage tail protein
LKAIADJA_01226 1.3e-303 lasA GH19 M Phage tail tape measure protein
LKAIADJA_01229 2.2e-87 S Phage tail tube protein
LKAIADJA_01230 1.6e-59
LKAIADJA_01231 1.8e-55
LKAIADJA_01232 8.3e-44
LKAIADJA_01233 1.8e-36
LKAIADJA_01235 5.3e-199 S Phage capsid family
LKAIADJA_01236 4.4e-90 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
LKAIADJA_01237 3.2e-185 S Phage portal protein
LKAIADJA_01238 9.6e-212 S Terminase
LKAIADJA_01239 3.1e-38
LKAIADJA_01240 5.5e-74 L HNH nucleases
LKAIADJA_01241 1.3e-50 L Transposase
LKAIADJA_01243 6.5e-29
LKAIADJA_01247 5.6e-63 S dUTPase
LKAIADJA_01251 9.7e-236 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LKAIADJA_01252 3.1e-104 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LKAIADJA_01253 4.4e-266 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LKAIADJA_01254 9.6e-189 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
LKAIADJA_01255 1.3e-282 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LKAIADJA_01256 1.6e-188 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LKAIADJA_01257 7.4e-80 ilvN 2.2.1.6 E Acetolactate synthase small
LKAIADJA_01258 0.0 ilvB 2.2.1.6 H acetolactate synthase
LKAIADJA_01259 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
LKAIADJA_01260 1.6e-71 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
LKAIADJA_01261 6.9e-108 yeaZ 2.3.1.234 O Glycoprotease family
LKAIADJA_01262 1.2e-79 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
LKAIADJA_01263 2.5e-178 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LKAIADJA_01264 1.5e-76 S Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LKAIADJA_01265 9.3e-260 mutS L ATPase domain of DNA mismatch repair MUTS family
LKAIADJA_01266 0.0 ydiF S ABC transporter, ATP-binding protein
LKAIADJA_01267 2.6e-112 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LKAIADJA_01268 1.4e-195 yeeE S Sulphur transport
LKAIADJA_01269 6.3e-37 yeeD O Belongs to the sulfur carrier protein TusA family
LKAIADJA_01270 8.9e-281 scrB 2.7.1.211, 3.2.1.26 GH32 G invertase
LKAIADJA_01271 1.1e-162 2.7.1.4 G COG0524 Sugar kinases, ribokinase family
LKAIADJA_01272 3.4e-129 agrA K Regulator
LKAIADJA_01273 2.6e-151 agrC 2.7.13.3 T GHKL domain
LKAIADJA_01274 2.9e-08 agrD S Staphylococcal AgrD protein
LKAIADJA_01275 7.8e-76 agrB KOT Essential for the production of a quorum sensing system signal molecule, the autoinducing peptide (AIP). This quorum sensing system is responsible for the regulation of the expression of virulence factor genes. Involved in the proteolytic processing of AgrD, the precursor of AIP
LKAIADJA_01276 2.9e-145 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
LKAIADJA_01277 1.7e-111 S Nitroreductase family
LKAIADJA_01278 3.1e-96 elrF DZ transferase activity, transferring acyl groups other than amino-acyl groups
LKAIADJA_01279 1.8e-120 ydiL S CAAX amino terminal protease family protein
LKAIADJA_01280 2e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LKAIADJA_01281 2.5e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LKAIADJA_01282 3e-81 S DinB family
LKAIADJA_01283 5.1e-248 bamJ E Aminotransferase
LKAIADJA_01284 3.4e-23
LKAIADJA_01285 2e-59 yvoA_1 K Transcriptional regulator
LKAIADJA_01286 1.1e-126 V ABC transporter, ATP-binding protein
LKAIADJA_01287 5e-82 S ABC-2 family transporter protein
LKAIADJA_01288 3.3e-158 V ABC transporter, ATP-binding protein
LKAIADJA_01289 3.8e-107
LKAIADJA_01290 1.2e-100 CO Thioredoxin
LKAIADJA_01291 4.8e-86 S Protein of unknown function (DUF1700)
LKAIADJA_01292 1e-119 S Putative adhesin
LKAIADJA_01293 3.5e-199 S Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase
LKAIADJA_01294 2.5e-22
LKAIADJA_01295 3.3e-71 S YolD-like protein
LKAIADJA_01296 1.7e-191 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
LKAIADJA_01297 1.7e-257 aldH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
LKAIADJA_01298 5.9e-166 ppaC 3.6.1.1 C Inorganic pyrophosphatase
LKAIADJA_01299 1.8e-101 pncA Q COG1335 Amidases related to nicotinamidase
LKAIADJA_01300 3e-201 M Pectate lyase superfamily protein
LKAIADJA_01301 9.4e-265 sdcS P symporter activity
LKAIADJA_01302 3.4e-141 pheA 4.2.1.51 E Prephenate dehydratase
LKAIADJA_01303 7.5e-197 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
LKAIADJA_01304 3.5e-261 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LKAIADJA_01305 2.8e-146 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LKAIADJA_01306 4.6e-100 yebE S UPF0316 protein
LKAIADJA_01307 1.6e-25 yebG S NETI protein
LKAIADJA_01308 2e-244 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LKAIADJA_01309 1.4e-47 yerC S Trp repressor protein
LKAIADJA_01310 1.4e-119 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
LKAIADJA_01311 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
LKAIADJA_01312 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LKAIADJA_01313 2.6e-214 camS S sex pheromone
LKAIADJA_01314 1.6e-277 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LKAIADJA_01315 2e-46 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LKAIADJA_01316 1.7e-271 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LKAIADJA_01317 5e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LKAIADJA_01318 9.4e-172 yegS 2.7.1.107 I Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid. Is a key enzyme involved in the production of lipoteichoic acid by reintroducing DAG formed from the breakdown of membrane phospholipids into the phosphatidylglycerol biosynthetic pathway (By similarity)
LKAIADJA_01319 8.5e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LKAIADJA_01320 2.6e-36 S Putative zincin peptidase
LKAIADJA_01321 1.5e-197 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LKAIADJA_01322 5.2e-101 polC 2.7.7.7 L DNA polymerase III
LKAIADJA_01323 9.3e-89 ftnA 1.16.3.2 P Iron-storage protein
LKAIADJA_01324 8.5e-243 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
LKAIADJA_01325 8.3e-131 cobQ2 S glutamine amidotransferase
LKAIADJA_01326 2.5e-170 S Aromatic acid exporter family member 1
LKAIADJA_01327 8e-137 map 3.4.11.18 E Methionine aminopeptidase
LKAIADJA_01328 2e-62
LKAIADJA_01329 3.9e-93 yvqF S Cell wall-active antibiotics response 4TMS YvqF
LKAIADJA_01330 9.7e-157 vraS 2.7.13.3 T Member of the two-component regulatory system VraS VraR involved in the control of the cell wall peptidoglycan biosynthesis
LKAIADJA_01331 6.5e-108 vraR K response regulator
LKAIADJA_01332 1.2e-170 yihY S Belongs to the UPF0761 family
LKAIADJA_01333 1.3e-42 yfkI S gas vesicle protein
LKAIADJA_01334 3e-73 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LKAIADJA_01335 2.7e-26 yfkK S Belongs to the UPF0435 family
LKAIADJA_01336 2.2e-232 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
LKAIADJA_01337 6.9e-87 ykhA 3.1.2.20 I Thioesterase superfamily
LKAIADJA_01338 1.2e-224 yfkA S Radical SAM
LKAIADJA_01339 8.7e-23
LKAIADJA_01340 1.5e-89 yhbO 3.5.1.124 S Intracellular protease
LKAIADJA_01341 4.2e-139 mgt 2.4.1.129, 3.4.16.4 GT51 M Peptidoglycan polymerase that catalyzes glycan chain elongation using lipid-linked disaccharide-pentapeptide as the substrate
LKAIADJA_01342 1.5e-136 recX 2.4.1.337 GT4 S Regulatory protein RecX
LKAIADJA_01343 1.4e-47 yfhH S Protein of unknown function (DUF1811)
LKAIADJA_01344 2.5e-278 3.6.3.38, 3.6.3.40 GM ABC-type polysaccharide polyol phosphate transport system ATPase component
LKAIADJA_01345 3.1e-84 wzm GM COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component
LKAIADJA_01346 2.6e-180 yfhP S membrane-bound metal-dependent
LKAIADJA_01347 5.3e-187 mutY L A G-specific
LKAIADJA_01348 2.1e-102 ygaC J Belongs to the UPF0374 family
LKAIADJA_01349 1.7e-286 ygaD V ABC transporter, ATP-binding protein
LKAIADJA_01350 1.3e-191 ygaE S Fusaric acid resistance protein family
LKAIADJA_01351 2.4e-242 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
LKAIADJA_01352 4e-75 bcp 1.11.1.15 O Redoxin
LKAIADJA_01353 9.1e-154 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LKAIADJA_01354 2.6e-82 perR K Belongs to the Fur family
LKAIADJA_01359 6.3e-38 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
LKAIADJA_01364 4.5e-55 S Transcriptional regulator, RinA family
LKAIADJA_01365 5e-47 S Phage terminase, small subunit
LKAIADJA_01366 6.2e-289 S Phage Terminase
LKAIADJA_01367 3.4e-23
LKAIADJA_01368 2.6e-233 S Phage portal protein
LKAIADJA_01369 2.4e-101 pi136 S Prohead protease
LKAIADJA_01370 2.5e-173 S Phage capsid family
LKAIADJA_01371 1.1e-53 S Phage gp6-like head-tail connector protein
LKAIADJA_01372 5.4e-13
LKAIADJA_01373 1.7e-69
LKAIADJA_01374 3.9e-69
LKAIADJA_01375 2.1e-114 S Phage tail tube protein
LKAIADJA_01376 1.6e-25
LKAIADJA_01377 2.9e-60
LKAIADJA_01378 0.0 M Phage tail tape measure protein
LKAIADJA_01379 1.8e-158 S Phage tail protein
LKAIADJA_01380 5.6e-265 S Prophage endopeptidase tail
LKAIADJA_01382 1.5e-37 S virus tail, fiber
LKAIADJA_01383 2.1e-28 S Domain of unknown function (DUF2479)
LKAIADJA_01384 3.2e-11
LKAIADJA_01385 2.4e-08 S Phage uncharacterised protein (Phage_XkdX)
LKAIADJA_01386 3e-72
LKAIADJA_01387 4.1e-63
LKAIADJA_01388 1.6e-43 S Domain of unknown function (DUF2479)
LKAIADJA_01389 2.6e-80 S Bacteriophage holin
LKAIADJA_01390 5.6e-248 3.5.1.28 M Ami_2
LKAIADJA_01391 3.2e-71 S YolD-like protein
LKAIADJA_01392 3.2e-86 S Chromatin associated protein KTI12
LKAIADJA_01393 2.3e-158 yfjD P Domain of unknown function DUF21
LKAIADJA_01394 7.8e-178 yrpB 1.13.12.16 S 2-nitropropane dioxygenase
LKAIADJA_01395 7.7e-171 yunF S Protein of unknown function DUF72
LKAIADJA_01396 6.7e-137 yunE S membrane transporter protein
LKAIADJA_01397 3.6e-241 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
LKAIADJA_01398 5.4e-175 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LKAIADJA_01399 7.9e-64 yutD S Protein of unknown function (DUF1027)
LKAIADJA_01400 2.6e-42 S Protein of unknown function (DUF3055)
LKAIADJA_01401 1.8e-72 yutE S Protein of unknown function DUF86
LKAIADJA_01402 6.4e-137 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LKAIADJA_01403 2.8e-171 gyaR 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LKAIADJA_01404 1.6e-17 S D-Ala-teichoic acid biosynthesis protein
LKAIADJA_01405 3.5e-253 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKAIADJA_01406 6.5e-213 dltB M membrane protein involved in D-alanine export
LKAIADJA_01407 7.6e-33 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKAIADJA_01408 1.6e-149 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LKAIADJA_01409 7.3e-39 nifU O NifU-like domain
LKAIADJA_01410 2.8e-51 yuzD S Protein of unknown function (DUF1462)
LKAIADJA_01411 5.2e-206 yutJ 1.6.99.3 C NADH dehydrogenase
LKAIADJA_01412 4.4e-41 yuzB S Belongs to the UPF0349 family
LKAIADJA_01413 1.8e-62 erpA S Belongs to the HesB IscA family
LKAIADJA_01414 1.6e-227 ndh 1.6.99.3 C oxidoreductase activity
LKAIADJA_01415 1e-252 pepA 3.4.11.1 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LKAIADJA_01416 4.6e-212 yuiF S Na+-H+ antiporter family
LKAIADJA_01417 7.1e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
LKAIADJA_01418 2.7e-224 P L-lysine 6-monooxygenase (NADPH-requiring)
LKAIADJA_01419 2.7e-50 phaG P Mnh complex is a Na( ) H( ) antiporter involved in Na( ) excretion
LKAIADJA_01420 6.7e-39 phaF P Na( ) H( ) antiporter subunit
LKAIADJA_01421 3e-76 mrpE P Na( ) H( ) antiporter subunit
LKAIADJA_01422 5.5e-262 mrpD CP Mnh complex is a Na( ) H( ) antiporter involved in Na( ) excretion
LKAIADJA_01423 9.7e-53 phaC 1.6.5.3 P Na( ) H( ) antiporter subunit
LKAIADJA_01424 1.4e-74 mrpB P Na( ) H( ) antiporter subunit
LKAIADJA_01425 0.0 phaA 1.6.5.3 CP -antiporter subunit
LKAIADJA_01426 6.8e-60 kapB T Kinase associated protein B
LKAIADJA_01427 7.1e-112 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LKAIADJA_01428 2.5e-68 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
LKAIADJA_01429 2.6e-208 yqiG C flavin oxidoreductase
LKAIADJA_01430 1.5e-230 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
LKAIADJA_01431 4.9e-240 gluD 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
LKAIADJA_01432 1.1e-167 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LKAIADJA_01433 9e-63 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
LKAIADJA_01434 1e-211 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LKAIADJA_01435 1e-45 arsR K arsenical resistance operon repressor
LKAIADJA_01436 7.8e-255 argH 4.3.2.1 E Argininosuccinate lyase
LKAIADJA_01437 5.8e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
LKAIADJA_01438 3e-251 pgi 5.3.1.9 G Belongs to the GPI family
LKAIADJA_01439 3.9e-91 yhjE S SNARE associated Golgi protein
LKAIADJA_01440 4.9e-85 spsA 3.4.21.89 U Belongs to the peptidase S26 family
LKAIADJA_01441 2.2e-102 spsB 3.4.21.89 U Belongs to the peptidase S26 family
LKAIADJA_01442 0.0 addB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation
LKAIADJA_01443 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
LKAIADJA_01444 5.6e-158 S Protein of unknown function (DUF418)
LKAIADJA_01445 1.1e-169 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
LKAIADJA_01446 1.4e-63 S UPF0344 protein
LKAIADJA_01447 5.7e-239 cdr 1.8.1.14 C Catalyzes specifically the NADPH-dependent reduction of coenzyme A disulfide
LKAIADJA_01448 1e-156 yitU 3.1.3.104 S hydrolases of the HAD superfamily
LKAIADJA_01449 3.6e-51 yitW S Iron-sulfur cluster assembly protein
LKAIADJA_01450 0.0 yrhL EI Acyltransferase family
LKAIADJA_01451 3.3e-71 MA20_04335 S Protein of unknown function (DUF1348)
LKAIADJA_01452 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
LKAIADJA_01453 4.8e-25 yjzD S Protein of unknown function (DUF2929)
LKAIADJA_01454 3.5e-174 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LKAIADJA_01455 2.1e-230 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LKAIADJA_01456 4.5e-201 G Major Facilitator Superfamily
LKAIADJA_01457 3e-31 S Domain of unknown function (DUF3899)
LKAIADJA_01458 8.1e-147 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LKAIADJA_01459 3.4e-165 oppC EP permease
LKAIADJA_01460 3.8e-204 oppD P Belongs to the ABC transporter superfamily
LKAIADJA_01461 2e-169 oppF P Belongs to the ABC transporter superfamily
LKAIADJA_01462 2e-289 oppA E ABC transporter substrate-binding protein
LKAIADJA_01463 5.7e-183 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
LKAIADJA_01464 1.2e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LKAIADJA_01465 3.6e-110 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
LKAIADJA_01466 4.7e-84 yjbF S Competence protein
LKAIADJA_01467 0.0 pepF E Oligopeptidase F
LKAIADJA_01468 7.3e-141 yjbH Q Thioredoxin
LKAIADJA_01469 2.9e-63 yjbI S Bacterial-like globin
LKAIADJA_01470 6.3e-89 yjbK S Adenylate cyclase
LKAIADJA_01471 2.2e-57 yjbL S Belongs to the UPF0738 family
LKAIADJA_01472 2.1e-114 yjbM 2.7.6.5 S GTP pyrophosphokinase
LKAIADJA_01473 6.2e-143 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LKAIADJA_01474 1.2e-141 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Pseudouridine synthase
LKAIADJA_01475 6.5e-225 mgtE P Acts as a magnesium transporter
LKAIADJA_01476 1.6e-300 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LKAIADJA_01477 8.2e-137 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase
LKAIADJA_01478 4.1e-182 yueF S AI-2E family transporter
LKAIADJA_01479 1e-282 alsT U Sodium alanine symporter family protein
LKAIADJA_01480 6.5e-139 yjcH P Esterase
LKAIADJA_01481 3.7e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
LKAIADJA_01482 2.1e-208 ltaA EGP Major facilitator Superfamily
LKAIADJA_01483 2.8e-221 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer two glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol) and beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol). Beta- diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
LKAIADJA_01484 2.7e-277 murE 6.3.2.10, 6.3.2.13, 6.3.2.7 M Catalyzes the addition of L-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LKAIADJA_01485 2.1e-30 yueH S YueH-like protein
LKAIADJA_01486 1.4e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LKAIADJA_01487 9.4e-144 P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
LKAIADJA_01488 9.4e-221 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LKAIADJA_01489 2.8e-233 ktrB P transport protein
LKAIADJA_01490 1.1e-291 F Belongs to the 5'-nucleotidase family
LKAIADJA_01491 4.7e-79 S protease
LKAIADJA_01492 1.4e-26 ykvS S Uncharacterized protein conserved in bacteria (DUF2187)
LKAIADJA_01493 2.9e-187 lplJ 6.3.1.20 H Lipoate-protein ligase
LKAIADJA_01494 4.7e-32 S IDEAL domain protein
LKAIADJA_01495 4.6e-105 comK K Competence transcription factor
LKAIADJA_01498 7.1e-48 yvlA
LKAIADJA_01500 5.4e-30 S TM2 domain
LKAIADJA_01501 1.2e-97 3.2.2.20 K Acetyltransferase (GNAT) domain
LKAIADJA_01502 1.2e-169 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
LKAIADJA_01503 3.4e-255 menF 5.4.4.2 HQ Isochorismate synthase
LKAIADJA_01504 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LKAIADJA_01505 7.5e-133 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
LKAIADJA_01506 6e-154 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LKAIADJA_01508 1.9e-50 sarZ K helix_turn_helix multiple antibiotic resistance protein
LKAIADJA_01509 1.1e-212 patA 2.6.1.1 E Aminotransferase
LKAIADJA_01510 1e-171 ykrP G Acyltransferase family
LKAIADJA_01511 2.6e-68 K Transcriptional regulator
LKAIADJA_01512 0.0 atl 3.2.1.96, 3.5.1.28 GH73 M the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis (By similarity)
LKAIADJA_01513 8.7e-72 yjcF S (GNAT) family
LKAIADJA_01514 4.5e-85 S Protein of unknown function (DUF2538)
LKAIADJA_01515 1.1e-178 ywtF K transcriptional
LKAIADJA_01516 2.3e-293 pmmB 5.4.2.2, 5.4.2.8 G Catalyzes the interconversion between glucose-6- phosphate and alpha-glucose-1-phosphate. This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. a glycolipid found in the membrane, which is also used as a membrane anchor for lipoteichoic acid (LTA) (By similarity)
LKAIADJA_01517 1.3e-186 pbpX V Autolysis and methicillin resistant-related protein
LKAIADJA_01518 1e-162 rihB 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
LKAIADJA_01519 1.6e-82 L COG1943 Transposase and inactivated derivatives
LKAIADJA_01520 5.8e-43 qoxD 1.10.3.12 C quinol oxidase, subunit
LKAIADJA_01521 3.3e-109 qoxC 1.10.3.12 C quinol oxidase, subunit
LKAIADJA_01522 0.0 qoxB 1.10.3.12, 1.9.3.1 C Belongs to the heme-copper respiratory oxidase family
LKAIADJA_01523 1.1e-201 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
LKAIADJA_01524 6.1e-46 G Domain of unknown function (DUF5011)
LKAIADJA_01525 1.7e-154 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LKAIADJA_01526 1.7e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LKAIADJA_01527 9.1e-201 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LKAIADJA_01528 1e-117 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
LKAIADJA_01529 9.2e-40 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LKAIADJA_01530 2.4e-124 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LKAIADJA_01531 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LKAIADJA_01532 7.1e-278 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LKAIADJA_01533 1.4e-184 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
LKAIADJA_01534 5.6e-98 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LKAIADJA_01535 1.9e-267 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
LKAIADJA_01536 6.9e-226 purD 6.3.4.13 F Belongs to the GARS family
LKAIADJA_01537 3.8e-92 ykoC P Cobalt transport protein
LKAIADJA_01538 7e-251 ykoD P ABC-type cobalt transport system ATPase component
LKAIADJA_01539 8.7e-91 ykoE S ABC-type cobalt transport system, permease component
LKAIADJA_01541 1.8e-184
LKAIADJA_01542 1.2e-219 ywbD 2.1.1.191 J S-adenosylmethionine-dependent methyltransferase
LKAIADJA_01543 2.6e-89 S protein domain associated with
LKAIADJA_01544 8.5e-41 ptsH G Phosphocarrier protein HPr
LKAIADJA_01545 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LKAIADJA_01546 1.4e-39 O Glutaredoxin
LKAIADJA_01547 4.5e-247 cydA 1.10.3.14 C oxidase, subunit
LKAIADJA_01548 5.5e-181 cydB 1.10.3.14 C cytochrome D ubiquinol oxidase subunit II
LKAIADJA_01549 2e-115 ktrA P potassium uptake protein TrkA
LKAIADJA_01550 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LKAIADJA_01551 2.2e-31 ykzG S Belongs to the UPF0356 family
LKAIADJA_01552 6.7e-41
LKAIADJA_01553 3.7e-99 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LKAIADJA_01554 9e-25 recN L Putative cell-wall binding lipoprotein
LKAIADJA_01555 2.7e-205 bkdA1 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
LKAIADJA_01556 7.4e-175 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LKAIADJA_01557 3.8e-187 pdhC 2.3.1.12 C acetyltransferase component of pyruvate dehydrogenase complex
LKAIADJA_01558 6.3e-260 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LKAIADJA_01559 4.8e-39 yktA S Belongs to the UPF0223 family
LKAIADJA_01560 3e-93 puuR K Transcriptional regulator
LKAIADJA_01561 3.4e-197 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
LKAIADJA_01562 6.4e-132 potB P ABC-type spermidine putrescine transport system, permease component I
LKAIADJA_01563 5.8e-133 potC P ABC-type spermidine putrescine transport system, permease component II
LKAIADJA_01564 4.4e-197 potD E Spermidine putrescine-binding periplasmic protein
LKAIADJA_01565 4e-74 S Protein of unknown function (DUF4064)
LKAIADJA_01566 1.1e-229 mntH P H( )-stimulated, divalent metal cation uptake system
LKAIADJA_01567 3e-71 S Protein of unknown function (DUF4064)
LKAIADJA_01568 3.5e-106 yktB S Belongs to the UPF0637 family
LKAIADJA_01569 1.4e-147 suhB 3.1.3.25 G Inositol monophosphatase
LKAIADJA_01570 0.0 typA T GTP-binding protein TypA
LKAIADJA_01571 9.5e-25 ylaI S Uncharacterized protein conserved in bacteria (DUF2197)
LKAIADJA_01572 9.2e-86 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LKAIADJA_01573 4.2e-43 ylaN S Belongs to the UPF0358 family
LKAIADJA_01574 4.6e-190 ftsW D Belongs to the SEDS family
LKAIADJA_01575 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LKAIADJA_01576 3.2e-156 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
LKAIADJA_01577 3.8e-149 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
LKAIADJA_01578 8.8e-81 S Protein of unknown function (DUF420)
LKAIADJA_01579 0.0 uvrA2 L Excinuclease
LKAIADJA_01580 1.1e-189 S protein with SCP PR1 domains
LKAIADJA_01581 1.4e-69 ylbF S Belongs to the UPF0342 family
LKAIADJA_01582 1.8e-162 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LKAIADJA_01583 1.9e-37 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
LKAIADJA_01584 1e-66
LKAIADJA_01585 2.1e-94 rsmD 2.1.1.171 L Conserved hypothetical protein 95
LKAIADJA_01586 1.7e-84 coaD 2.7.7.3 F Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LKAIADJA_01587 6.4e-69 mepB S MepB protein
LKAIADJA_01588 4.7e-189 ylbM S Belongs to the UPF0348 family
LKAIADJA_01589 2.5e-92 yceD S metal-binding, possibly nucleic acid-binding protein
LKAIADJA_01590 1e-18 rpmF J Belongs to the bacterial ribosomal protein bL32 family
LKAIADJA_01591 1.5e-161 M Peptidase family M23
LKAIADJA_01592 1.1e-127 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LKAIADJA_01593 4.7e-199 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LKAIADJA_01594 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LKAIADJA_01595 1.3e-155 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LKAIADJA_01596 2.9e-41 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LKAIADJA_01597 8.4e-77 cvpA S Colicin V production protein
LKAIADJA_01598 2e-308 polX L DNA polymerase
LKAIADJA_01599 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LKAIADJA_01600 1.6e-54 trxA O Component of the thioredoxin-thioredoxin reductase system. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity)
LKAIADJA_01601 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LKAIADJA_01602 4.6e-106 sdhC C succinate dehydrogenase
LKAIADJA_01603 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
LKAIADJA_01604 3.1e-150 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
LKAIADJA_01605 2.1e-148 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
LKAIADJA_01606 6.1e-100 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LKAIADJA_01607 5.7e-86 S Phosphoesterase
LKAIADJA_01610 5.3e-15 S antibacterial protein
LKAIADJA_01611 1.4e-07 S antibacterial protein
LKAIADJA_01612 1.1e-15 S antibacterial protein
LKAIADJA_01613 4.6e-123 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S hydrolase
LKAIADJA_01614 3.1e-80 ylbP K N-acetyltransferase
LKAIADJA_01615 1e-277 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
LKAIADJA_01616 1.2e-76 mraZ K Belongs to the MraZ family
LKAIADJA_01617 9.2e-167 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LKAIADJA_01618 1.1e-58 ftsL D Cell division protein FtsL
LKAIADJA_01619 0.0 ftsI 3.4.16.4 M penicillin-binding protein
LKAIADJA_01620 6e-169 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LKAIADJA_01621 5.1e-251 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LKAIADJA_01622 2.6e-126 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LKAIADJA_01623 6.5e-233 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LKAIADJA_01624 6.1e-184 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LKAIADJA_01625 1.5e-138 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
LKAIADJA_01626 5.2e-119 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LKAIADJA_01627 2e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LKAIADJA_01628 7.9e-40 yggT S YGGT family
LKAIADJA_01629 6.6e-85 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
LKAIADJA_01630 3.8e-63 divIVA D initiation protein
LKAIADJA_01631 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LKAIADJA_01632 3.9e-150 1.13.11.2 S Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LKAIADJA_01633 1.8e-65 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LKAIADJA_01634 1.2e-171 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LKAIADJA_01635 1.6e-86 pyrR 2.4.2.9 F Belongs to the purine pyrimidine phosphoribosyltransferase family. PyrR subfamily
LKAIADJA_01636 7e-205 pyrP F Permease family
LKAIADJA_01637 3.4e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
LKAIADJA_01638 2.8e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LKAIADJA_01639 8e-210 carA 6.3.5.5 F Belongs to the CarA family
LKAIADJA_01640 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthetase ammonia chain
LKAIADJA_01641 3.3e-116 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LKAIADJA_01642 3.9e-97 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LKAIADJA_01643 3e-24
LKAIADJA_01644 6.7e-255 yfiU EGP Sugar (and other) transporter
LKAIADJA_01645 2.6e-144 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LKAIADJA_01646 3.9e-69 S 3-demethylubiquinone-9 3-methyltransferase domain protein
LKAIADJA_01647 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
LKAIADJA_01648 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
LKAIADJA_01649 9.6e-29 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LKAIADJA_01650 1.5e-214 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LKAIADJA_01651 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LKAIADJA_01652 1.9e-67 K Acetyltransferase (GNAT) domain
LKAIADJA_01653 4.1e-119 ydaF_2 J Acetyltransferase (GNAT) domain
LKAIADJA_01654 2.6e-80 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LKAIADJA_01655 8.1e-163 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LKAIADJA_01656 3.7e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LKAIADJA_01657 9.1e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
LKAIADJA_01658 2.8e-134 stp 3.1.3.16 T phosphatase
LKAIADJA_01659 0.0 prkC 2.7.11.1 KLT Serine threonine protein kinase
LKAIADJA_01660 5.6e-158 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LKAIADJA_01661 1.1e-107 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
LKAIADJA_01662 8.1e-106 thiN 2.7.6.2 H thiamine pyrophosphokinase
LKAIADJA_01663 6.5e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
LKAIADJA_01664 2.5e-59 asp S Asp23 family, cell envelope-related function
LKAIADJA_01665 9.9e-297 yloV S kinase related to dihydroxyacetone kinase
LKAIADJA_01666 1.5e-118 sdaAB 4.3.1.17 E L-serine dehydratase
LKAIADJA_01667 8.6e-151 sdaAA 4.3.1.17 E L-serine dehydratase
LKAIADJA_01668 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LKAIADJA_01669 1.7e-261 mpl 3.4.24.28, 3.4.24.29 E COG3227 Zinc metalloprotease (elastase)
LKAIADJA_01670 5.8e-95 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
LKAIADJA_01671 3.7e-174 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LKAIADJA_01672 1.6e-163 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
LKAIADJA_01673 8.2e-126 IQ reductase
LKAIADJA_01674 6.8e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
LKAIADJA_01675 9.6e-127 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LKAIADJA_01676 0.0 smc D Required for chromosome condensation and partitioning
LKAIADJA_01677 1.8e-194 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LKAIADJA_01678 3.1e-32 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LKAIADJA_01679 2.9e-225 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LKAIADJA_01680 1.8e-245 ntaA C Luciferase-like monooxygenase
LKAIADJA_01681 6.4e-126 IQ KR domain
LKAIADJA_01682 3.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
LKAIADJA_01683 7.2e-89 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LKAIADJA_01684 2.2e-139 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
LKAIADJA_01685 1.5e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LKAIADJA_01686 0.0 yfhO S overlaps another CDS with the same product name
LKAIADJA_01687 0.0 yfhO S overlaps another CDS with the same product name
LKAIADJA_01688 8.5e-159 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LKAIADJA_01689 3.7e-129 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LKAIADJA_01690 1.3e-213 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
LKAIADJA_01691 1.9e-156 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LKAIADJA_01692 8.2e-109 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
LKAIADJA_01693 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LKAIADJA_01694 1.9e-242 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LKAIADJA_01695 2.7e-163 xerC D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids
LKAIADJA_01696 2.2e-91 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LKAIADJA_01697 3.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LKAIADJA_01698 4.7e-132 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LKAIADJA_01699 4.8e-140 rpsB J Belongs to the universal ribosomal protein uS2 family
LKAIADJA_01700 3.5e-152 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LKAIADJA_01701 2.7e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
LKAIADJA_01702 1.3e-88 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LKAIADJA_01703 3.9e-123 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LKAIADJA_01704 1.9e-133 cdsA 2.7.7.41 I Belongs to the CDS family
LKAIADJA_01705 2.9e-227 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
LKAIADJA_01706 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LKAIADJA_01707 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LKAIADJA_01708 1.8e-78 rimP S Required for maturation of 30S ribosomal subunits
LKAIADJA_01709 5.6e-209 nusA K Participates in both transcription termination and antitermination
LKAIADJA_01710 3.1e-41 ylxR K nucleic-acid-binding protein implicated in transcription termination
LKAIADJA_01711 1e-48 ylxQ J ribosomal protein
LKAIADJA_01712 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LKAIADJA_01713 8.1e-169
LKAIADJA_01714 9e-148
LKAIADJA_01715 1.9e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LKAIADJA_01716 3.3e-153 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LKAIADJA_01717 2.4e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
LKAIADJA_01718 1e-33 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LKAIADJA_01719 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
LKAIADJA_01720 8.7e-309 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LKAIADJA_01721 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
LKAIADJA_01722 2.5e-124 K transcriptional
LKAIADJA_01723 2.7e-225 ymfF S Peptidase M16 inactive domain
LKAIADJA_01724 1.1e-226 ymfH S Peptidase, M16
LKAIADJA_01725 4.7e-123 IQ short chain dehydrogenase reductase family
LKAIADJA_01726 3.7e-151 ymfK S Protein of unknown function (DUF3388)
LKAIADJA_01727 7.1e-60 S Helix-turn-helix domain
LKAIADJA_01728 2.5e-98 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LKAIADJA_01729 3.8e-194 cinA 3.5.1.42 S Belongs to the CinA family
LKAIADJA_01730 1.5e-189 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LKAIADJA_01731 8.6e-218 rny S Endoribonuclease that initiates mRNA decay
LKAIADJA_01732 4.2e-30
LKAIADJA_01733 1.1e-147 ymdB S YmdB-like protein
LKAIADJA_01734 0.0 korA 1.2.7.11, 1.2.7.3 C ferredoxin oxidoreductase
LKAIADJA_01735 1.3e-162 korB 1.2.7.11, 1.2.7.3 C COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit
LKAIADJA_01736 7.9e-98 ymaC S phage-related replication protein
LKAIADJA_01737 1.1e-104 ymaC S phage-related replication protein
LKAIADJA_01738 7.2e-60 ywgB K Transcriptional regulator
LKAIADJA_01739 2.8e-96 ahpF 1.8.1.9 O Pyridine nucleotide-disulphide oxidoreductase
LKAIADJA_01740 3.4e-46 M1-594 S Thiamine-binding protein
LKAIADJA_01741 2.8e-293 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LKAIADJA_01742 1.7e-47 ymcA 3.6.3.21 S Belongs to the UPF0342 family
LKAIADJA_01743 1.9e-75 thiW S Thiamine-precursor transporter protein (ThiW)
LKAIADJA_01744 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LKAIADJA_01745 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LKAIADJA_01746 1.1e-92 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LKAIADJA_01747 1.7e-177 mccF V LD-carboxypeptidase
LKAIADJA_01748 5.9e-117 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
LKAIADJA_01749 1.3e-292 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LKAIADJA_01750 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LKAIADJA_01751 2.6e-169 ytpA I Serine aminopeptidase, S33
LKAIADJA_01752 1.4e-162 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LKAIADJA_01753 2.4e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
LKAIADJA_01754 4.3e-88 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
LKAIADJA_01755 4.7e-219 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LKAIADJA_01756 6.7e-226 ynbB 4.4.1.1 P aluminum resistance protein
LKAIADJA_01757 7.3e-59 glnR K transcriptional
LKAIADJA_01758 4e-264 glnA 6.3.1.2 E Glutamine synthetase
LKAIADJA_01759 2.2e-17
LKAIADJA_01760 1.1e-82 K Acetyltransferase (GNAT) domain
LKAIADJA_01762 2.2e-88 nucI 3.1.31.1 L thermonuclease
LKAIADJA_01763 5.6e-134 M Membrane
LKAIADJA_01764 2.4e-30 yetM CH FAD binding domain
LKAIADJA_01765 9.1e-105 yetJ S Belongs to the BI1 family
LKAIADJA_01766 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
LKAIADJA_01767 2.7e-144 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LKAIADJA_01768 2.2e-34
LKAIADJA_01769 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LKAIADJA_01770 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
LKAIADJA_01771 3.3e-121 yetF S membrane
LKAIADJA_01772 6.6e-251 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
LKAIADJA_01773 1.4e-161 lplC G Binding-protein-dependent transport system inner membrane component
LKAIADJA_01774 1.5e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
LKAIADJA_01775 2.4e-289 lplA G Bacterial extracellular solute-binding protein
LKAIADJA_01776 0.0 yetA
LKAIADJA_01777 6.5e-156 yesZ 3.2.1.23 G beta-galactosidase activity
LKAIADJA_01778 1.5e-63 yesZ 3.2.1.23 G beta-galactosidase activity
LKAIADJA_01779 1.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
LKAIADJA_01780 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
LKAIADJA_01781 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
LKAIADJA_01782 8.8e-113 yesV S Protein of unknown function, DUF624
LKAIADJA_01783 8.7e-127 yesU S Domain of unknown function (DUF1961)
LKAIADJA_01784 1.4e-132 E GDSL-like Lipase/Acylhydrolase
LKAIADJA_01785 0.0 yesS K Transcriptional regulator
LKAIADJA_01786 1.9e-197 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
LKAIADJA_01787 1.4e-119 yesQ P Binding-protein-dependent transport system inner membrane component
LKAIADJA_01788 6.2e-171 yesP G Binding-protein-dependent transport system inner membrane component
LKAIADJA_01789 5.2e-245 yesO G Bacterial extracellular solute-binding protein
LKAIADJA_01790 4.6e-158 yesN K helix_turn_helix, arabinose operon control protein
LKAIADJA_01791 0.0 yesM 2.7.13.3 T Histidine kinase
LKAIADJA_01792 4.5e-101 yesL S Protein of unknown function, DUF624
LKAIADJA_01794 2.8e-99 yesJ K Acetyltransferase (GNAT) family
LKAIADJA_01795 5.2e-104 cotJC P Spore Coat
LKAIADJA_01796 5.6e-45 cotJB S CotJB protein
LKAIADJA_01797 1.5e-44 cotJA S Spore coat associated protein JA (CotJA)
LKAIADJA_01798 2e-144 yesF GM NAD(P)H-binding
LKAIADJA_01799 1.6e-79 yesE S SnoaL-like domain
LKAIADJA_01800 6.7e-99 dhaR3 K Transcriptional regulator
LKAIADJA_01802 2.7e-126 yeeN K transcriptional regulatory protein
LKAIADJA_01804 7.4e-211 S Tetratricopeptide repeat
LKAIADJA_01805 3.6e-58 3.4.24.40 CO amine dehydrogenase activity
LKAIADJA_01806 5.9e-96 3.4.24.40 CO amine dehydrogenase activity
LKAIADJA_01807 0.0 L nucleic acid phosphodiester bond hydrolysis
LKAIADJA_01808 2.7e-82 S Protein of unknown function, DUF600
LKAIADJA_01811 3.7e-101 S response regulator aspartate phosphatase
LKAIADJA_01813 6.4e-249 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LKAIADJA_01814 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LKAIADJA_01815 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LKAIADJA_01816 1.3e-148 yerO K Transcriptional regulator
LKAIADJA_01817 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LKAIADJA_01818 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LKAIADJA_01819 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LKAIADJA_01820 7.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LKAIADJA_01821 1.6e-123 sapB S MgtC SapB transporter
LKAIADJA_01822 1.9e-194 yerI S homoserine kinase type II (protein kinase fold)
LKAIADJA_01824 5.4e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
LKAIADJA_01825 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LKAIADJA_01826 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
LKAIADJA_01827 4.9e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
LKAIADJA_01828 4.4e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
LKAIADJA_01829 4.8e-51 yerC S protein conserved in bacteria
LKAIADJA_01830 1.8e-189 yerB S Protein of unknown function (DUF3048) C-terminal domain
LKAIADJA_01831 0.0 yerA 3.5.4.2 F adenine deaminase
LKAIADJA_01832 1.4e-15 S Protein of unknown function (DUF2892)
LKAIADJA_01833 4.3e-231 yjeH E Amino acid permease
LKAIADJA_01834 1e-72 K helix_turn_helix ASNC type
LKAIADJA_01835 6.1e-230 purD 6.3.4.13 F Belongs to the GARS family
LKAIADJA_01836 2.7e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
LKAIADJA_01837 3.7e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LKAIADJA_01838 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
LKAIADJA_01839 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LKAIADJA_01840 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LKAIADJA_01841 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LKAIADJA_01842 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LKAIADJA_01843 3.7e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
LKAIADJA_01844 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LKAIADJA_01845 8.5e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LKAIADJA_01846 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LKAIADJA_01847 8e-28 yebG S NETI protein
LKAIADJA_01848 4e-93 yebE S UPF0316 protein
LKAIADJA_01850 2.3e-118 yebC M Membrane
LKAIADJA_01851 3.3e-210 pbuG S permease
LKAIADJA_01853 8.3e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
LKAIADJA_01854 0.0 yebA E COG1305 Transglutaminase-like enzymes
LKAIADJA_01855 7.5e-222 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
LKAIADJA_01856 4.3e-175 yeaC S COG0714 MoxR-like ATPases
LKAIADJA_01857 3.5e-152 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LKAIADJA_01858 1.3e-252 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
LKAIADJA_01859 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
LKAIADJA_01860 6.7e-176 yeaA S Protein of unknown function (DUF4003)
LKAIADJA_01861 1.1e-138 ydjP I Alpha/beta hydrolase family
LKAIADJA_01862 1.4e-34 ydjO S Cold-inducible protein YdjO
LKAIADJA_01864 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LKAIADJA_01865 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LKAIADJA_01866 4.7e-41 fer C Ferredoxin
LKAIADJA_01867 5.5e-200 ypbB 5.1.3.1 S protein conserved in bacteria
LKAIADJA_01868 6e-285 recQ 3.6.4.12 L DNA helicase
LKAIADJA_01869 6.9e-99 ypbD S metal-dependent membrane protease
LKAIADJA_01870 5.5e-74 ypbE M Lysin motif
LKAIADJA_01871 2.8e-81 ypbF S Protein of unknown function (DUF2663)
LKAIADJA_01872 1.5e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
LKAIADJA_01873 9.1e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
LKAIADJA_01874 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
LKAIADJA_01875 1.5e-175 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
LKAIADJA_01876 1.5e-118 prsW S Involved in the degradation of specific anti-sigma factors
LKAIADJA_01877 2.4e-151 sleB 3.5.1.28 M Spore cortex-lytic enzyme
LKAIADJA_01878 9.3e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
LKAIADJA_01879 1.2e-107 ypfA M Flagellar protein YcgR
LKAIADJA_01880 1.8e-23 S Family of unknown function (DUF5359)
LKAIADJA_01881 2.8e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
LKAIADJA_01882 2.1e-205 rpsA 1.17.7.4 J Ribosomal protein S1
LKAIADJA_01883 1.3e-182 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LKAIADJA_01884 1e-07 S YpzI-like protein
LKAIADJA_01885 3.3e-101 yphA
LKAIADJA_01886 2.5e-161 seaA S YIEGIA protein
LKAIADJA_01887 6e-28 ypzH
LKAIADJA_01888 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
LKAIADJA_01889 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
LKAIADJA_01890 3.3e-135 yphF
LKAIADJA_01891 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LKAIADJA_01892 1.8e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LKAIADJA_01893 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
LKAIADJA_01894 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
LKAIADJA_01895 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
LKAIADJA_01896 4.2e-132 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
LKAIADJA_01897 7.6e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LKAIADJA_01898 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
LKAIADJA_01899 1.2e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
LKAIADJA_01900 1.2e-216 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LKAIADJA_01901 5.8e-205 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LKAIADJA_01902 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
LKAIADJA_01903 5.6e-294 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LKAIADJA_01904 6.7e-179 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LKAIADJA_01905 9.5e-114 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
LKAIADJA_01906 1.8e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
LKAIADJA_01907 8.4e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
LKAIADJA_01908 3e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
LKAIADJA_01909 1.4e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LKAIADJA_01910 2.6e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
LKAIADJA_01911 7.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
LKAIADJA_01912 1e-232 S COG0457 FOG TPR repeat
LKAIADJA_01913 8.1e-99 ypiB S Belongs to the UPF0302 family
LKAIADJA_01914 7.2e-77 ypiF S Protein of unknown function (DUF2487)
LKAIADJA_01915 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
LKAIADJA_01916 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
LKAIADJA_01917 4.3e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
LKAIADJA_01918 3.4e-98 ypjA S membrane
LKAIADJA_01919 1e-142 ypjB S sporulation protein
LKAIADJA_01920 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
LKAIADJA_01921 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
LKAIADJA_01922 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LKAIADJA_01923 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
LKAIADJA_01924 1.7e-128 bshB1 S proteins, LmbE homologs
LKAIADJA_01925 6.9e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
LKAIADJA_01926 2e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LKAIADJA_01927 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LKAIADJA_01928 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
LKAIADJA_01929 4.7e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LKAIADJA_01930 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LKAIADJA_01931 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
LKAIADJA_01932 6.7e-23 ypmA S Protein of unknown function (DUF4264)
LKAIADJA_01933 3.4e-80 ypmB S protein conserved in bacteria
LKAIADJA_01934 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
LKAIADJA_01935 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
LKAIADJA_01936 5.7e-129 dnaD L DNA replication protein DnaD
LKAIADJA_01937 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LKAIADJA_01938 8e-93 ypoC
LKAIADJA_01939 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
LKAIADJA_01940 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LKAIADJA_01941 4.8e-176 yppC S Protein of unknown function (DUF2515)
LKAIADJA_01944 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
LKAIADJA_01946 2.1e-48 yppG S YppG-like protein
LKAIADJA_01947 8.6e-72 hspX O Belongs to the small heat shock protein (HSP20) family
LKAIADJA_01948 1.6e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
LKAIADJA_01949 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
LKAIADJA_01950 1.6e-235 yprB L RNase_H superfamily
LKAIADJA_01951 4.4e-96 ypsA S Belongs to the UPF0398 family
LKAIADJA_01952 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LKAIADJA_01953 9.2e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
LKAIADJA_01955 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
LKAIADJA_01956 3.5e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKAIADJA_01957 4.8e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
LKAIADJA_01958 3.9e-187 ptxS K transcriptional
LKAIADJA_01959 1.1e-186 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
LKAIADJA_01960 3e-102 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
LKAIADJA_01961 1.9e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
LKAIADJA_01962 4.6e-293 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LKAIADJA_01963 1.1e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LKAIADJA_01964 1.5e-226 pbuX F xanthine
LKAIADJA_01965 7.7e-205 bcsA Q Naringenin-chalcone synthase
LKAIADJA_01966 5.1e-87 ypbQ S protein conserved in bacteria
LKAIADJA_01968 0.0 ypbR S Dynamin family
LKAIADJA_01969 2.9e-38 ypbS S Protein of unknown function (DUF2533)
LKAIADJA_01970 2e-07
LKAIADJA_01971 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
LKAIADJA_01973 1.8e-66 rnhA 3.1.26.4 L Ribonuclease
LKAIADJA_01974 3.8e-105 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LKAIADJA_01975 1.7e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
LKAIADJA_01976 2.6e-27 ypeQ S Zinc-finger
LKAIADJA_01977 3.1e-107 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
LKAIADJA_01978 2.2e-80 yokK S SMI1 / KNR4 family
LKAIADJA_01979 1.9e-94 yokJ S SMI1 / KNR4 family (SUKH-1)
LKAIADJA_01980 3.8e-291 UW nuclease activity
LKAIADJA_01981 1.1e-101 yokH G SMI1 / KNR4 family
LKAIADJA_01982 2.4e-275 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
LKAIADJA_01983 1e-198 yobO M Pectate lyase superfamily protein
LKAIADJA_01984 2.4e-221 yobO M Pectate lyase superfamily protein
LKAIADJA_01985 9.3e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
LKAIADJA_01986 3.8e-136 yobQ K helix_turn_helix, arabinose operon control protein
LKAIADJA_01987 1.2e-140 yobR 2.3.1.1 J FR47-like protein
LKAIADJA_01988 3.6e-97 yobS K Transcriptional regulator
LKAIADJA_01989 7.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
LKAIADJA_01990 8.3e-87 yobU K Bacterial transcription activator, effector binding domain
LKAIADJA_01991 6.2e-171 yobV K WYL domain
LKAIADJA_01992 6.3e-91 yobW
LKAIADJA_01993 1e-51 czrA K transcriptional
LKAIADJA_01994 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LKAIADJA_01995 1.5e-92 yozB S membrane
LKAIADJA_01996 8.6e-142
LKAIADJA_01997 2.6e-91 yocC
LKAIADJA_01998 6e-185 yocD 3.4.17.13 V peptidase S66
LKAIADJA_01999 1.2e-202 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
LKAIADJA_02000 9.2e-198 desK 2.7.13.3 T Histidine kinase
LKAIADJA_02001 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LKAIADJA_02003 2.6e-107 yocH CBM50 M COG1388 FOG LysM repeat
LKAIADJA_02004 0.0 recQ 3.6.4.12 L DNA helicase
LKAIADJA_02005 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LKAIADJA_02006 3.3e-83 dksA T general stress protein
LKAIADJA_02007 5.4e-53 yocL
LKAIADJA_02008 6.2e-32
LKAIADJA_02009 3.7e-87 yocM O Belongs to the small heat shock protein (HSP20) family
LKAIADJA_02010 1.1e-40 yozN
LKAIADJA_02011 1.9e-36 yocN
LKAIADJA_02012 4.2e-56 yozO S Bacterial PH domain
LKAIADJA_02013 2.7e-31 yozC
LKAIADJA_02014 5.2e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
LKAIADJA_02015 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
LKAIADJA_02016 6e-165 sodA 1.15.1.1 P Superoxide dismutase
LKAIADJA_02017 4.5e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
LKAIADJA_02018 1.1e-167 yocS S -transporter
LKAIADJA_02019 9.1e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
LKAIADJA_02020 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
LKAIADJA_02021 0.0 yojO P Von Willebrand factor
LKAIADJA_02022 3.2e-161 yojN S ATPase family associated with various cellular activities (AAA)
LKAIADJA_02023 5.6e-109 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LKAIADJA_02024 1.8e-197 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
LKAIADJA_02025 5.9e-230 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
LKAIADJA_02026 5.8e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LKAIADJA_02028 2.2e-241 norM V Multidrug efflux pump
LKAIADJA_02029 9.3e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LKAIADJA_02030 2.1e-125 yojG S deacetylase
LKAIADJA_02031 2.2e-60 yojF S Protein of unknown function (DUF1806)
LKAIADJA_02032 1.5e-43
LKAIADJA_02033 4.3e-161 rarD S -transporter
LKAIADJA_02034 5.5e-59 yozR S COG0071 Molecular chaperone (small heat shock protein)
LKAIADJA_02035 2e-09
LKAIADJA_02036 1e-198 gntP EG COG2610 H gluconate symporter and related permeases
LKAIADJA_02037 1.4e-63 yodA S tautomerase
LKAIADJA_02038 6.3e-54 yodB K transcriptional
LKAIADJA_02039 1.4e-107 yodC C nitroreductase
LKAIADJA_02040 2.7e-111 mhqD S Carboxylesterase
LKAIADJA_02041 1.2e-137 yodE E COG0346 Lactoylglutathione lyase and related lyases
LKAIADJA_02042 3.3e-28 yodE E COG0346 Lactoylglutathione lyase and related lyases
LKAIADJA_02043 6.2e-28 S Protein of unknown function (DUF3311)
LKAIADJA_02044 1.1e-265 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LKAIADJA_02045 3.4e-250 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
LKAIADJA_02046 2.4e-127 yodH Q Methyltransferase
LKAIADJA_02047 2e-23 yodI
LKAIADJA_02048 2.1e-138 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
LKAIADJA_02049 1.2e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
LKAIADJA_02050 5.3e-09
LKAIADJA_02051 7.9e-54 yodL S YodL-like
LKAIADJA_02052 6.6e-105 yodM 3.6.1.27 I Acid phosphatase homologues
LKAIADJA_02053 2.8e-24 yozD S YozD-like protein
LKAIADJA_02055 6e-123 yodN
LKAIADJA_02056 3.1e-36 yozE S Belongs to the UPF0346 family
LKAIADJA_02057 2.9e-47 yokU S YokU-like protein, putative antitoxin
LKAIADJA_02058 3.9e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
LKAIADJA_02059 8.8e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
LKAIADJA_02060 1.2e-257 yodQ 3.5.1.16 E Acetylornithine deacetylase
LKAIADJA_02061 5.2e-116 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
LKAIADJA_02062 2.4e-09 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LKAIADJA_02063 2.1e-238 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LKAIADJA_02064 9.2e-144 yiiD K acetyltransferase
LKAIADJA_02065 8e-254 cgeD M maturation of the outermost layer of the spore
LKAIADJA_02066 5.9e-38 cgeC
LKAIADJA_02067 4.8e-64 cgeA
LKAIADJA_02068 1.4e-186 cgeB S Spore maturation protein
LKAIADJA_02069 6.4e-210 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
LKAIADJA_02070 5.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
LKAIADJA_02071 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
LKAIADJA_02072 3.5e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LKAIADJA_02073 1.6e-70 ypoP K transcriptional
LKAIADJA_02074 1.9e-221 mepA V MATE efflux family protein
LKAIADJA_02075 1.2e-28 ypmT S Uncharacterized ympT
LKAIADJA_02076 1.1e-98 ypmS S protein conserved in bacteria
LKAIADJA_02077 3.7e-137 ypmR E GDSL-like Lipase/Acylhydrolase
LKAIADJA_02078 3.5e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
LKAIADJA_02079 3.1e-40 ypmP S Protein of unknown function (DUF2535)
LKAIADJA_02080 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LKAIADJA_02081 3.4e-183 pspF K Transcriptional regulator
LKAIADJA_02082 4.2e-110 hlyIII S protein, Hemolysin III
LKAIADJA_02083 1.4e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
LKAIADJA_02084 1.4e-92 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LKAIADJA_02085 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
LKAIADJA_02086 4.3e-112 ypjP S YpjP-like protein
LKAIADJA_02087 1.6e-143 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
LKAIADJA_02088 1.7e-75 yphP S Belongs to the UPF0403 family
LKAIADJA_02089 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
LKAIADJA_02090 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
LKAIADJA_02091 3.5e-106 ypgQ S phosphohydrolase
LKAIADJA_02092 9.2e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
LKAIADJA_02093 4.7e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LKAIADJA_02094 2.3e-215 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
LKAIADJA_02095 1e-30 cspD K Cold-shock protein
LKAIADJA_02096 6.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LKAIADJA_02097 7.5e-106 tmrB S AAA domain
LKAIADJA_02098 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LKAIADJA_02099 1.2e-93 ycgI S Domain of unknown function (DUF1989)
LKAIADJA_02100 1.2e-152 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
LKAIADJA_02101 7.8e-148 yqcI S YqcI/YcgG family
LKAIADJA_02102 3.3e-289 lctP C L-lactate permease
LKAIADJA_02103 3.6e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
LKAIADJA_02104 2.7e-97 amyE 3.2.1.1 GH13 G alpha-amylase
LKAIADJA_02105 2.6e-269 amyE 3.2.1.1 GH13 G alpha-amylase
LKAIADJA_02106 4.5e-80 ycgB
LKAIADJA_02107 2.5e-256 ycgA S Membrane
LKAIADJA_02108 1.5e-214 amhX S amidohydrolase
LKAIADJA_02109 1.5e-163 opuAC E glycine betaine
LKAIADJA_02110 1.3e-127 opuAB P glycine betaine
LKAIADJA_02111 2.5e-228 proV 3.6.3.32 E glycine betaine
LKAIADJA_02112 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
LKAIADJA_02113 5.8e-203 yceJ EGP Uncharacterised MFS-type transporter YbfB
LKAIADJA_02114 1.5e-217 naiP P Uncharacterised MFS-type transporter YbfB
LKAIADJA_02115 2e-192 yceH P Belongs to the TelA family
LKAIADJA_02116 0.0 yceG S Putative component of 'biosynthetic module'
LKAIADJA_02117 1.4e-136 terC P Protein of unknown function (DUF475)
LKAIADJA_02118 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
LKAIADJA_02119 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
LKAIADJA_02120 1.6e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
LKAIADJA_02121 9.8e-183 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LKAIADJA_02122 6.4e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
LKAIADJA_02123 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
LKAIADJA_02124 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
LKAIADJA_02125 6.5e-153 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
LKAIADJA_02126 2.1e-176 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
LKAIADJA_02127 4e-139 IQ Enoyl-(Acyl carrier protein) reductase
LKAIADJA_02128 1.2e-35 S response regulator aspartate phosphatase
LKAIADJA_02129 3.2e-104 S response regulator aspartate phosphatase
LKAIADJA_02130 7.3e-94 cwlK M D-alanyl-D-alanine carboxypeptidase
LKAIADJA_02131 1.2e-256 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
LKAIADJA_02132 1.1e-272 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
LKAIADJA_02133 1.1e-170 ycdA S Domain of unknown function (DUF5105)
LKAIADJA_02134 1e-173 yccK C Aldo keto reductase
LKAIADJA_02135 4.2e-201 natB CP ABC-2 family transporter protein
LKAIADJA_02136 1.2e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
LKAIADJA_02137 9.7e-60 lytR_2 T LytTr DNA-binding domain
LKAIADJA_02138 7.1e-36 lytR_2 T LytTr DNA-binding domain
LKAIADJA_02139 6.6e-160 2.7.13.3 T GHKL domain
LKAIADJA_02140 1.6e-199 yccF K DNA-templated transcriptional preinitiation complex assembly
LKAIADJA_02141 4.6e-56 S RDD family
LKAIADJA_02142 1.6e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
LKAIADJA_02143 1.9e-198 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
LKAIADJA_02144 3.1e-101 yxaF K Transcriptional regulator
LKAIADJA_02145 1.8e-230 lmrB EGP the major facilitator superfamily
LKAIADJA_02146 1.6e-202 ycbU E Selenocysteine lyase
LKAIADJA_02147 1.9e-118 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LKAIADJA_02148 4.9e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LKAIADJA_02149 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
LKAIADJA_02150 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
LKAIADJA_02151 2.9e-44 ycbR T vWA found in TerF C terminus
LKAIADJA_02152 9e-72 ycbR T vWA found in TerF C terminus
LKAIADJA_02153 3.4e-76 sleB 3.5.1.28 M Cell wall
LKAIADJA_02154 2.9e-50 ycbP S Protein of unknown function (DUF2512)
LKAIADJA_02155 2.5e-113 S ABC-2 family transporter protein
LKAIADJA_02156 3.5e-166 ycbN V ABC transporter, ATP-binding protein
LKAIADJA_02157 2.2e-168 T PhoQ Sensor
LKAIADJA_02158 6.5e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKAIADJA_02159 9.9e-169 eamA1 EG spore germination
LKAIADJA_02160 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
LKAIADJA_02161 1.5e-172 ycbJ S Macrolide 2'-phosphotransferase
LKAIADJA_02162 2.9e-78 garD 4.2.1.42, 4.2.1.7 G Altronate
LKAIADJA_02163 5.6e-183 garD 4.2.1.42, 4.2.1.7 G Altronate
LKAIADJA_02164 2.1e-123 ycbG K FCD
LKAIADJA_02165 9.4e-269 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
LKAIADJA_02166 2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
LKAIADJA_02167 4.9e-271 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LKAIADJA_02168 1e-173 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
LKAIADJA_02169 2.3e-168 glnL T Regulator
LKAIADJA_02170 3.9e-78 phoQ 2.7.13.3 T Histidine kinase
LKAIADJA_02171 3.1e-121 phoQ 2.7.13.3 T Histidine kinase
LKAIADJA_02172 2.9e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
LKAIADJA_02173 8.1e-255 agcS E Sodium alanine symporter
LKAIADJA_02174 3e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
LKAIADJA_02175 1.1e-259 mmuP E amino acid
LKAIADJA_02176 2.7e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
LKAIADJA_02178 3.1e-128 K UTRA
LKAIADJA_02179 5.7e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LKAIADJA_02180 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LKAIADJA_02181 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LKAIADJA_02182 1.5e-191 yceA S Belongs to the UPF0176 family
LKAIADJA_02183 3e-44 ybfN
LKAIADJA_02184 2.4e-147 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
LKAIADJA_02185 2.7e-85 ybfM S SNARE associated Golgi protein
LKAIADJA_02186 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LKAIADJA_02187 7e-164 S Alpha/beta hydrolase family
LKAIADJA_02189 1.1e-175 mpr 3.4.21.19 M Belongs to the peptidase S1B family
LKAIADJA_02190 9.9e-211 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LKAIADJA_02191 3.3e-144 msmR K AraC-like ligand binding domain
LKAIADJA_02192 4.4e-161 ybfH EG EamA-like transporter family
LKAIADJA_02193 0.0 ybfG M Domain of unknown function (DUF1906)
LKAIADJA_02195 1.1e-220 ybfB G COG0477 Permeases of the major facilitator superfamily
LKAIADJA_02196 3.7e-168 ybfA 3.4.15.5 K FR47-like protein
LKAIADJA_02197 4.7e-33 S Protein of unknown function (DUF2651)
LKAIADJA_02198 7.3e-258 glpT G -transporter
LKAIADJA_02199 5.3e-164 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LKAIADJA_02200 1.2e-73 yneK S Protein of unknown function (DUF2621)
LKAIADJA_02201 4.1e-65 hspX O Spore coat protein
LKAIADJA_02202 3.9e-19 sspP S Belongs to the SspP family
LKAIADJA_02203 2.2e-14 sspO S Belongs to the SspO family
LKAIADJA_02204 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LKAIADJA_02205 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LKAIADJA_02206 3.1e-08 sspN S Small acid-soluble spore protein N family
LKAIADJA_02207 3.9e-35 tlp S Belongs to the Tlp family
LKAIADJA_02208 1.2e-73 yneP S Thioesterase-like superfamily
LKAIADJA_02209 2.2e-53 yneQ
LKAIADJA_02210 4.1e-49 yneR S Belongs to the HesB IscA family
LKAIADJA_02211 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LKAIADJA_02212 6.6e-69 yccU S CoA-binding protein
LKAIADJA_02213 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LKAIADJA_02214 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LKAIADJA_02215 2.3e-12
LKAIADJA_02216 7.9e-70 ynfC
LKAIADJA_02217 5.9e-250 agcS E Sodium alanine symporter
LKAIADJA_02218 4.2e-294 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
LKAIADJA_02220 2.4e-155 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
LKAIADJA_02221 3.5e-76 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
LKAIADJA_02222 6.2e-293 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
LKAIADJA_02223 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
LKAIADJA_02224 5.5e-104 yngC S membrane-associated protein
LKAIADJA_02225 1.2e-232 nrnB S phosphohydrolase (DHH superfamily)
LKAIADJA_02226 2e-288 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
LKAIADJA_02227 1.7e-134 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
LKAIADJA_02228 4.4e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
LKAIADJA_02229 6.6e-31 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
LKAIADJA_02230 3.3e-250 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
LKAIADJA_02231 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LKAIADJA_02232 2.7e-208 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
LKAIADJA_02233 8.5e-303 yngK T Glycosyl hydrolase-like 10
LKAIADJA_02234 9.9e-62 yngL S Protein of unknown function (DUF1360)
LKAIADJA_02235 6.1e-38 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
LKAIADJA_02236 2.5e-153 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
LKAIADJA_02237 1e-154 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
LKAIADJA_02238 9.1e-218 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
LKAIADJA_02239 1.7e-290 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKAIADJA_02240 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKAIADJA_02241 6.8e-273 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
LKAIADJA_02242 7.1e-186 yoxA 5.1.3.3 G Aldose 1-epimerase
LKAIADJA_02243 2.3e-246 yoeA V MATE efflux family protein
LKAIADJA_02244 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
LKAIADJA_02246 2.2e-96 L Integrase
LKAIADJA_02247 8.7e-34 yoeD G Helix-turn-helix domain
LKAIADJA_02248 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
LKAIADJA_02249 8.8e-156 gltR1 K Transcriptional regulator
LKAIADJA_02250 1.2e-185 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
LKAIADJA_02251 2.3e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
LKAIADJA_02252 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
LKAIADJA_02253 7.8e-155 gltC K Transcriptional regulator
LKAIADJA_02254 1.3e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LKAIADJA_02255 1.6e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LKAIADJA_02256 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
LKAIADJA_02257 2.4e-122 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
LKAIADJA_02258 7.1e-39 yoxC S Bacterial protein of unknown function (DUF948)
LKAIADJA_02259 7.9e-124 yoxB
LKAIADJA_02260 3.9e-93 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LKAIADJA_02261 4e-234 yoaB EGP Major facilitator Superfamily
LKAIADJA_02262 2.2e-279 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
LKAIADJA_02263 5.8e-183 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LKAIADJA_02264 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LKAIADJA_02265 1.1e-33 yoaF
LKAIADJA_02266 6.5e-08 ywlA S Uncharacterised protein family (UPF0715)
LKAIADJA_02267 2.6e-13
LKAIADJA_02268 7.7e-35 S Protein of unknown function (DUF4025)
LKAIADJA_02269 7.4e-183 mcpU NT methyl-accepting chemotaxis protein
LKAIADJA_02270 2.4e-278 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
LKAIADJA_02271 5.5e-132 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
LKAIADJA_02272 2.3e-111 yoaK S Membrane
LKAIADJA_02273 2.1e-196 pelB 4.2.2.10, 4.2.2.2 G Amb_all
LKAIADJA_02274 3.9e-130 yoqW S Belongs to the SOS response-associated peptidase family
LKAIADJA_02277 5e-164 oxdC 4.1.1.2 G Oxalate decarboxylase
LKAIADJA_02278 1.7e-51 oxdC 4.1.1.2 G Oxalate decarboxylase
LKAIADJA_02281 4.4e-83
LKAIADJA_02282 4.3e-169 yoaR V vancomycin resistance protein
LKAIADJA_02283 7.3e-75 yoaS S Protein of unknown function (DUF2975)
LKAIADJA_02284 4.4e-30 yozG K Transcriptional regulator
LKAIADJA_02285 2.4e-147 yoaT S Protein of unknown function (DUF817)
LKAIADJA_02286 8.2e-158 yoaU K LysR substrate binding domain
LKAIADJA_02287 5.3e-156 yijE EG EamA-like transporter family
LKAIADJA_02288 1.6e-76 yoaW
LKAIADJA_02289 3.6e-143 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
LKAIADJA_02290 7.7e-146 tagG GM Transport permease protein
LKAIADJA_02291 4e-177 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M teichoic acid biosynthesis protein
LKAIADJA_02292 1.5e-189 tagX GT2,GT4 S teichoic acid biosynthesis protein
LKAIADJA_02293 1.4e-71 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
LKAIADJA_02294 2.6e-236 pbp4 3.4.16.4 M Belongs to the peptidase S11 family
LKAIADJA_02295 1.4e-306 msbA2 3.6.3.44 V ABC transporter
LKAIADJA_02296 1.7e-216 nupG F Nucleoside
LKAIADJA_02297 9.9e-144 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LKAIADJA_02298 1.7e-148 fhuC 3.6.3.34 HP ATP-binding protein
LKAIADJA_02299 2.6e-167 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKAIADJA_02300 1.2e-167 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKAIADJA_02301 4.9e-163 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
LKAIADJA_02302 1.4e-93 dhaL 2.7.1.121 S Dihydroxyacetone kinase
LKAIADJA_02303 1.7e-52 dhaM 2.7.1.121 S transporter subunit IIA
LKAIADJA_02304 2.4e-84
LKAIADJA_02305 4.9e-188 S membrane
LKAIADJA_02306 5.2e-187 I Carboxylesterase family
LKAIADJA_02307 5.9e-91 yhhY 2.1.2.9 M Acetyltransferase (GNAT) domain
LKAIADJA_02308 2.7e-155 1.1.1.271, 4.1.1.35 GM ADP-glyceromanno-heptose 6-epimerase activity
LKAIADJA_02309 1e-119 K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKAIADJA_02310 1e-174 T PhoQ Sensor
LKAIADJA_02311 2.6e-109 ykaA P Protein of unknown function DUF47
LKAIADJA_02312 3.8e-158 pit P phosphate transporter
LKAIADJA_02313 3.5e-130 cwlS 3.5.1.28 CBM50 M CHAP domain
LKAIADJA_02314 7.1e-113 yetJ S Belongs to the BI1 family
LKAIADJA_02315 0.0 K helix_turn_helix, arabinose operon control protein
LKAIADJA_02316 1e-49 sarX K regulator
LKAIADJA_02317 1.5e-121 yeeN K transcriptional regulatory protein
LKAIADJA_02318 3.3e-86 S Cupin superfamily (DUF985)
LKAIADJA_02319 4.7e-210 yxjG 2.1.1.14 E Cobalamin-independent synthase, Catalytic domain
LKAIADJA_02320 1e-96 S Protein of unknown function (DUF402)
LKAIADJA_02321 2.5e-158 ccpC K Transcriptional regulator
LKAIADJA_02322 1e-210 setA EGP Major facilitator Superfamily
LKAIADJA_02323 1.7e-74 yqgC S Protein of unknown function (DUF456)
LKAIADJA_02324 9.3e-193 araJ EGP Major facilitator Superfamily
LKAIADJA_02325 1.4e-119 M1-1017 S Protein of unknown function (DUF1129)
LKAIADJA_02326 8.6e-65 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
LKAIADJA_02327 2e-08
LKAIADJA_02328 4e-47
LKAIADJA_02329 3.4e-100 1.1.1.25, 2.3.1.128, 4.2.1.10 J (GNAT) family
LKAIADJA_02330 2.7e-250 K helix_turn_helix gluconate operon transcriptional repressor
LKAIADJA_02331 5.5e-91 argO S LysE type translocator
LKAIADJA_02332 9.1e-101 yvdD 3.2.2.10 S Belongs to the LOG family
LKAIADJA_02333 1.3e-76 yaiI S Belongs to the UPF0178 family
LKAIADJA_02334 4.8e-27
LKAIADJA_02335 3.7e-149 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
LKAIADJA_02336 3.6e-283 cydD V ABC transporter, ATP-binding protein
LKAIADJA_02337 1e-285 cydC V ABC transporter, ATP-binding protein
LKAIADJA_02338 2.2e-73 mgrA K transcriptional
LKAIADJA_02339 1.7e-160 cobW S Cobalamin synthesis protein cobW C-terminal domain
LKAIADJA_02340 5.5e-148 ydhF S aldo keto reductase
LKAIADJA_02341 1.5e-38
LKAIADJA_02342 2.3e-97 dedA 3.1.3.1 S SNARE associated Golgi protein
LKAIADJA_02343 1.2e-161 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
LKAIADJA_02344 4.8e-31
LKAIADJA_02345 4.4e-78 S Protein of unknown function (DUF1361)
LKAIADJA_02346 1.4e-69 S Domain of unknown function (DUF296)
LKAIADJA_02347 3.1e-204 norA EGP Major facilitator Superfamily
LKAIADJA_02348 2.9e-110
LKAIADJA_02349 1.5e-155 galU 2.7.7.9 M Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. a glycolipid found in the membrane, which is also used as a membrane anchor for lipoteichoic acid (LTA) (By similarity)
LKAIADJA_02350 9.8e-72 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LKAIADJA_02352 1.1e-130 fruR K transcriptional regulators of sugar metabolism
LKAIADJA_02353 2e-161 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
LKAIADJA_02354 0.0 fruA 2.7.1.202 G PTS system, fructose-specific
LKAIADJA_02355 9e-212 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
LKAIADJA_02356 3.1e-248 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
LKAIADJA_02357 1.2e-141 ytbE 1.1.1.346 S aldo keto reductase
LKAIADJA_02358 3e-193 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LKAIADJA_02359 1.2e-15 ydaS S Transglycosylase associated protein
LKAIADJA_02360 1.8e-75
LKAIADJA_02361 6.7e-133 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
LKAIADJA_02362 1.7e-75 queD 4.1.2.50, 4.2.3.12 H synthase
LKAIADJA_02363 5.3e-124 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LKAIADJA_02364 6.4e-97 pabA 2.6.1.85, 4.1.3.27 EH component II
LKAIADJA_02365 2.3e-196 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
LKAIADJA_02366 4.3e-96 pabC 2.6.1.42, 4.1.3.38 EH COG0115 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase
LKAIADJA_02367 2.5e-08
LKAIADJA_02368 2.2e-128 kipI 3.5.1.54 E allophanate hydrolase subunit 1
LKAIADJA_02369 6.4e-190 kipA 6.3.4.6 E allophanate hydrolase subunit 2
LKAIADJA_02370 0.0 ltaS 2.7.8.20 M Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate, a reaction that presumably uses phosphatidylglycerol (PG) as substrate
LKAIADJA_02371 2.8e-143 zupT P divalent heavy-metal cations transporter
LKAIADJA_02372 0.0 yfmR S ABC transporter, ATP-binding protein
LKAIADJA_02373 0.0 recQ 3.6.4.12 L DNA helicase
LKAIADJA_02374 3e-168 proV E ATP-binding protein
LKAIADJA_02375 8e-269 proWX P Glycine betaine
LKAIADJA_02376 1.8e-187 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LKAIADJA_02377 4e-101 yorS 3.1.3.5 S 5'-3'-deoxyribonucleotidase
LKAIADJA_02379 1.2e-74 ydcK S Belongs to the SprT family
LKAIADJA_02380 0.0 yhgF K accessory protein
LKAIADJA_02381 3.1e-136 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LKAIADJA_02382 4.7e-82 rsbW 2.7.11.1 T Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
LKAIADJA_02383 9.7e-55 rsbV T Belongs to the anti-sigma-factor antagonist family
LKAIADJA_02384 4.7e-185 rsbU 3.1.3.3 KT Serine phosphatase RsbU regulator of sigma subunit
LKAIADJA_02385 3.6e-58 ndoA L Toxic component of a toxin-antitoxin (TA) module
LKAIADJA_02386 6.1e-24 mazE S Antitoxin component of a type II toxin-antitoxin (TA) system. Labile antitoxin that binds to cognate MazF toxin and counteracts its endoribonuclease activity
LKAIADJA_02387 2.8e-213 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LKAIADJA_02388 8.3e-52 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LKAIADJA_02389 2.1e-61 S Bacterial PH domain
LKAIADJA_02390 1.8e-241 ydbT S Overlaps another CDS with the same product name
LKAIADJA_02391 2.7e-77 S overlaps another CDS with the same product name
LKAIADJA_02392 4.9e-250 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LKAIADJA_02393 1.4e-235 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LKAIADJA_02394 6.6e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
LKAIADJA_02395 1.5e-201 rodA D Belongs to the SEDS family
LKAIADJA_02396 7.2e-15
LKAIADJA_02397 8.7e-25
LKAIADJA_02398 1.1e-44 csoR S protein conserved in bacteria
LKAIADJA_02399 4.7e-282 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LKAIADJA_02400 9.7e-99 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
LKAIADJA_02401 4.9e-154 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LKAIADJA_02402 2.9e-103 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
LKAIADJA_02403 2.1e-127 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LKAIADJA_02404 5.8e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
LKAIADJA_02405 2.5e-116 tenA 3.5.99.2 F Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LKAIADJA_02406 7.5e-36 sceD M Is able to cleave peptidoglycan and affects clumping and separation of bacterial cells
LKAIADJA_02407 1.1e-66 ssb_2 L Single-stranded DNA-binding protein
LKAIADJA_02408 4.8e-73 ywpF S YwpF-like protein
LKAIADJA_02409 1.9e-77 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LKAIADJA_02410 1.1e-228 murA 2.5.1.7 M Belongs to the EPSP synthase family. MurA subfamily
LKAIADJA_02411 4e-34 ywzB S Protein of unknown function (DUF1146)
LKAIADJA_02412 2.2e-64 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
LKAIADJA_02413 1.8e-262 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LKAIADJA_02414 1.1e-153 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LKAIADJA_02415 1.2e-277 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LKAIADJA_02416 6.5e-88 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LKAIADJA_02417 6.4e-56 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LKAIADJA_02418 2.3e-25 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LKAIADJA_02419 4e-133 atpB C it plays a direct role in the translocation of protons across the membrane
LKAIADJA_02420 1.6e-34 S ATP synthase I chain
LKAIADJA_02421 2.1e-205 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LKAIADJA_02422 3e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LKAIADJA_02423 2.1e-235 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LKAIADJA_02424 4.1e-87 ywlG S Belongs to the UPF0340 family
LKAIADJA_02425 6.6e-64 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T low molecular weight
LKAIADJA_02426 1e-182 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LKAIADJA_02427 3.8e-143 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LKAIADJA_02428 9.6e-176 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LKAIADJA_02429 2.5e-109 tdk 2.7.1.21 F thymidine kinase
LKAIADJA_02430 1.1e-42 rpmE2 J Ribosomal protein L31
LKAIADJA_02431 3.8e-243 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LKAIADJA_02432 6e-266 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
LKAIADJA_02433 8.1e-54 K Transcriptional regulator
LKAIADJA_02434 3e-229 murA 2.5.1.7 M Belongs to the EPSP synthase family. MurA subfamily
LKAIADJA_02435 4.7e-157 fba 4.1.2.13 G aldolase
LKAIADJA_02436 1.2e-86 S Domain of unknown function (DUF2529)
LKAIADJA_02437 2.2e-311 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LKAIADJA_02438 8.8e-53 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LKAIADJA_02439 2.8e-162 JK spermine spermidine acetyltransferase
LKAIADJA_02440 3.5e-61 phnB5 S protein conserved in bacteria
LKAIADJA_02441 3.6e-143 coaW 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LKAIADJA_02442 1.5e-115 S Protein of unknown function (DUF2750)
LKAIADJA_02443 2.4e-212 6.3.2.4 M COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ)
LKAIADJA_02444 2.3e-210 hmrA F Peptidase dimerisation domain
LKAIADJA_02445 9.9e-85 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LKAIADJA_02446 5.4e-51 S Membrane
LKAIADJA_02447 3.8e-226 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
LKAIADJA_02448 4.1e-229 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
LKAIADJA_02449 3.1e-116 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LKAIADJA_02450 1.6e-131 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
LKAIADJA_02451 3.1e-75 dps P Belongs to the Dps family
LKAIADJA_02452 3.1e-148 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LKAIADJA_02453 1.2e-67 yuxK S Protein of unknown function, DUF393
LKAIADJA_02454 2e-263 MA20_25125 S EVE domain
LKAIADJA_02455 3.6e-161 yeiH S Conserved hypothetical protein 698
LKAIADJA_02456 2e-30
LKAIADJA_02457 3.6e-171 manA 5.3.1.8 G mannose-6-phosphate isomerase
LKAIADJA_02458 3.3e-116 yvfI K FCD
LKAIADJA_02459 1.7e-98 GM NmrA-like family
LKAIADJA_02460 4.6e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
LKAIADJA_02461 1.1e-151 czcD P Co Zn Cd efflux system component
LKAIADJA_02462 1.9e-138 T Calcineurin-like phosphoesterase superfamily domain
LKAIADJA_02463 6.8e-129
LKAIADJA_02464 9.7e-155 cof S Sucrose-6F-phosphate phosphohydrolase
LKAIADJA_02465 8e-135 modF 3.6.3.21, 3.6.3.34 P ABC transporter, ATP-binding protein
LKAIADJA_02466 4.3e-56 S Uncharacterized protein conserved in bacteria (DUF2200)
LKAIADJA_02467 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LKAIADJA_02468 1.6e-232 mtlA 2.7.1.197 G PTS system mannitol-specific
LKAIADJA_02469 4.5e-214 mtlR 2.7.1.202 GKT Mga helix-turn-helix domain
LKAIADJA_02470 9.4e-136 mtlR 2.7.1.202 GKT Mga helix-turn-helix domain
LKAIADJA_02471 9.8e-71 mtlF 2.7.1.197 G Mannitol-specific phosphotransferase enzyme IIA component
LKAIADJA_02472 2.8e-199 mtlD 1.1.1.17 G Mannitol-1-phosphate 5-dehydrogenase
LKAIADJA_02473 5.7e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LKAIADJA_02474 5.1e-157 ybbR S YbbR-like protein
LKAIADJA_02475 1.4e-139 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LKAIADJA_02476 8.7e-162 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
LKAIADJA_02477 1.5e-228 yitG EGP Major facilitator Superfamily
LKAIADJA_02478 2.8e-154 yitH K Acetyltransferase (GNAT) domain
LKAIADJA_02479 1.3e-70 yjcF S Acetyltransferase (GNAT) domain
LKAIADJA_02480 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
LKAIADJA_02481 3.3e-54 yajQ S Belongs to the UPF0234 family
LKAIADJA_02482 4.5e-160 cvfB S protein conserved in bacteria
LKAIADJA_02483 8.5e-94
LKAIADJA_02484 5.4e-167
LKAIADJA_02485 1.5e-97 S Sporulation delaying protein SdpA
LKAIADJA_02486 1.5e-58 K Transcriptional regulator PadR-like family
LKAIADJA_02487 1.6e-92
LKAIADJA_02488 1.4e-44 yitR S Domain of unknown function (DUF3784)
LKAIADJA_02489 4.2e-308 nprB 3.4.24.28 E Peptidase M4
LKAIADJA_02490 3.5e-157 yitS S protein conserved in bacteria
LKAIADJA_02491 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
LKAIADJA_02492 5e-73 ipi S Intracellular proteinase inhibitor
LKAIADJA_02493 1.5e-26 S Protein of unknown function (DUF3813)
LKAIADJA_02494 6e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
LKAIADJA_02495 2.9e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
LKAIADJA_02496 6.2e-51 yitW S metal-sulfur cluster biosynthetic enzyme
LKAIADJA_02497 8.3e-268 yitY C D-arabinono-1,4-lactone oxidase
LKAIADJA_02498 1.7e-88 norB G Major Facilitator Superfamily
LKAIADJA_02499 3.6e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LKAIADJA_02500 6.5e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LKAIADJA_02501 1.6e-135 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
LKAIADJA_02502 5.4e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
LKAIADJA_02503 1.3e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
LKAIADJA_02504 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
LKAIADJA_02505 1.5e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LKAIADJA_02506 9.5e-28 yjzC S YjzC-like protein
LKAIADJA_02507 2.3e-16 yjzD S Protein of unknown function (DUF2929)
LKAIADJA_02508 1.8e-141 yjaU I carboxylic ester hydrolase activity
LKAIADJA_02509 6.4e-99 yjaV
LKAIADJA_02510 1.6e-182 med S Transcriptional activator protein med
LKAIADJA_02511 7.3e-26 comZ S ComZ
LKAIADJA_02512 2.7e-22 yjzB
LKAIADJA_02513 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LKAIADJA_02514 8.9e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LKAIADJA_02515 2.5e-149 yjaZ O Zn-dependent protease
LKAIADJA_02516 1.8e-184 appD P Belongs to the ABC transporter superfamily
LKAIADJA_02517 3.6e-185 appF E Belongs to the ABC transporter superfamily
LKAIADJA_02518 1.4e-279 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
LKAIADJA_02519 1.9e-167 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LKAIADJA_02520 1.8e-154 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LKAIADJA_02521 2.8e-145 yjbA S Belongs to the UPF0736 family
LKAIADJA_02522 3e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
LKAIADJA_02523 0.0 oppA E ABC transporter substrate-binding protein
LKAIADJA_02524 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LKAIADJA_02525 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LKAIADJA_02526 3.4e-197 oppD P Belongs to the ABC transporter superfamily
LKAIADJA_02527 5.5e-172 oppF E Belongs to the ABC transporter superfamily
LKAIADJA_02528 2.7e-203 yjbB EGP Major Facilitator Superfamily
LKAIADJA_02529 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LKAIADJA_02530 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LKAIADJA_02531 6e-112 yjbE P Integral membrane protein TerC family
LKAIADJA_02532 4.4e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
LKAIADJA_02533 4e-220 yjbF S Competence protein
LKAIADJA_02534 0.0 pepF E oligoendopeptidase F
LKAIADJA_02535 1.8e-20
LKAIADJA_02537 1.2e-168 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
LKAIADJA_02538 3.7e-72 yjbI S Bacterial-like globin
LKAIADJA_02539 3.2e-98 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LKAIADJA_02540 4.1e-101 yjbK S protein conserved in bacteria
LKAIADJA_02541 7.1e-62 yjbL S Belongs to the UPF0738 family
LKAIADJA_02542 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
LKAIADJA_02543 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LKAIADJA_02544 5.2e-159 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LKAIADJA_02545 1.5e-127 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
LKAIADJA_02546 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LKAIADJA_02547 1.1e-135 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LKAIADJA_02548 3.9e-105 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
LKAIADJA_02549 4.4e-216 thiO 1.4.3.19 E Glycine oxidase
LKAIADJA_02550 8.8e-30 thiS H thiamine diphosphate biosynthetic process
LKAIADJA_02551 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
LKAIADJA_02552 6.7e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LKAIADJA_02553 1.3e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
LKAIADJA_02554 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
LKAIADJA_02555 1.4e-52 yjbX S Spore coat protein
LKAIADJA_02556 5.2e-83 cotZ S Spore coat protein
LKAIADJA_02557 3.4e-96 cotY S Spore coat protein Z
LKAIADJA_02558 6.4e-77 cotX S Spore Coat Protein X and V domain
LKAIADJA_02559 3e-32 cotW
LKAIADJA_02560 2.3e-55 cotV S Spore Coat Protein X and V domain
LKAIADJA_02561 4.3e-56 yjcA S Protein of unknown function (DUF1360)
LKAIADJA_02564 2.9e-38 spoVIF S Stage VI sporulation protein F
LKAIADJA_02565 0.0 yjcD 3.6.4.12 L DNA helicase
LKAIADJA_02566 1.7e-38
LKAIADJA_02567 3.9e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LKAIADJA_02568 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
LKAIADJA_02569 1.8e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
LKAIADJA_02570 8.6e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
LKAIADJA_02571 6.5e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
LKAIADJA_02572 1.7e-96 rimJ 2.3.1.128 J Alanine acetyltransferase
LKAIADJA_02573 1.3e-210 yjcL S Protein of unknown function (DUF819)
LKAIADJA_02576 1.3e-37
LKAIADJA_02577 1e-29
LKAIADJA_02578 5e-238 M nucleic acid phosphodiester bond hydrolysis
LKAIADJA_02579 9.6e-11
LKAIADJA_02580 3.4e-33 K Helix-turn-helix XRE-family like proteins
LKAIADJA_02581 3.3e-40
LKAIADJA_02583 3.6e-185 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
LKAIADJA_02584 8.7e-30 cspL K Cold shock
LKAIADJA_02585 6.1e-79 carD K Transcription factor
LKAIADJA_02586 6.1e-144 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LKAIADJA_02587 1.1e-68 rhaS5 K AraC-like ligand binding domain
LKAIADJA_02588 6.4e-85 rhaS5 K AraC-like ligand binding domain
LKAIADJA_02589 7.8e-169 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LKAIADJA_02590 2.1e-117 ydeE K AraC family transcriptional regulator
LKAIADJA_02591 6.6e-262 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LKAIADJA_02592 5.1e-216 ydeG EGP Major facilitator superfamily
LKAIADJA_02593 1.4e-44 ydeH
LKAIADJA_02594 6.4e-105 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
LKAIADJA_02595 7.8e-112
LKAIADJA_02596 1.1e-31 S SNARE associated Golgi protein
LKAIADJA_02597 8.3e-15 ptsH G PTS HPr component phosphorylation site
LKAIADJA_02598 3.4e-84 K Transcriptional regulator C-terminal region
LKAIADJA_02599 3.2e-71 ydeK EG -transporter
LKAIADJA_02600 8.1e-87 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LKAIADJA_02601 7.4e-166 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LKAIADJA_02602 1.2e-73 maoC I N-terminal half of MaoC dehydratase
LKAIADJA_02603 2.8e-105 ydeN S Serine hydrolase
LKAIADJA_02604 2.2e-41 K HxlR-like helix-turn-helix
LKAIADJA_02605 5.4e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
LKAIADJA_02606 2e-68 ydeP K Transcriptional regulator
LKAIADJA_02607 3.7e-32 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
LKAIADJA_02608 1.6e-48 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
LKAIADJA_02609 8.1e-192 ydeR EGP Major facilitator Superfamily
LKAIADJA_02610 4.6e-103 ydeS K Transcriptional regulator
LKAIADJA_02611 8.2e-57 arsR K transcriptional
LKAIADJA_02612 7e-229 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LKAIADJA_02613 1.7e-72 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
LKAIADJA_02614 2.1e-148 ydfB J GNAT acetyltransferase
LKAIADJA_02615 2.2e-157 ydfC EG EamA-like transporter family
LKAIADJA_02616 7.9e-274 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LKAIADJA_02617 5e-116 ydfE S Flavin reductase like domain
LKAIADJA_02618 7.8e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
LKAIADJA_02619 1e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LKAIADJA_02621 2.7e-176 ydfH 2.7.13.3 T Histidine kinase
LKAIADJA_02622 3.5e-109 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LKAIADJA_02623 0.0 ydfJ S drug exporters of the RND superfamily
LKAIADJA_02624 1.4e-175 S Alpha/beta hydrolase family
LKAIADJA_02625 8.5e-117 S Protein of unknown function (DUF554)
LKAIADJA_02626 1.9e-144 K Bacterial transcription activator, effector binding domain
LKAIADJA_02627 1.5e-153 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LKAIADJA_02628 4e-110 ydfN C nitroreductase
LKAIADJA_02629 3.4e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
LKAIADJA_02630 8.8e-63 mhqP S DoxX
LKAIADJA_02631 1e-54 traF CO Thioredoxin
LKAIADJA_02632 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
LKAIADJA_02633 6.3e-29
LKAIADJA_02635 1.3e-25 ydfR S Protein of unknown function (DUF421)
LKAIADJA_02636 5.1e-28 ydfR S Protein of unknown function (DUF421)
LKAIADJA_02637 1.5e-121 ydfS S Protein of unknown function (DUF421)
LKAIADJA_02638 1.9e-74 cotP O Belongs to the small heat shock protein (HSP20) family
LKAIADJA_02639 2.3e-37 ydgA S Spore germination protein gerPA/gerPF
LKAIADJA_02640 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
LKAIADJA_02641 1.7e-97 K Bacterial regulatory proteins, tetR family
LKAIADJA_02642 3.4e-50 S DoxX-like family
LKAIADJA_02643 1.7e-84 yycN 2.3.1.128 K Acetyltransferase
LKAIADJA_02644 4.6e-302 expZ S ABC transporter
LKAIADJA_02645 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
LKAIADJA_02646 8.7e-90 dinB S DinB family
LKAIADJA_02647 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
LKAIADJA_02648 0.0 ydgH S drug exporters of the RND superfamily
LKAIADJA_02649 1e-113 drgA C nitroreductase
LKAIADJA_02650 7.1e-69 ydgJ K Winged helix DNA-binding domain
LKAIADJA_02651 2.2e-208 tcaB EGP Major facilitator Superfamily
LKAIADJA_02652 1.2e-121 ydhB S membrane transporter protein
LKAIADJA_02653 6.5e-122 ydhC K FCD
LKAIADJA_02654 3.3e-244 ydhD M Glycosyl hydrolase
LKAIADJA_02655 4.4e-211 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
LKAIADJA_02656 1.3e-125
LKAIADJA_02657 2e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
LKAIADJA_02658 4.3e-67 frataxin S Domain of unknown function (DU1801)
LKAIADJA_02660 2.9e-84 K Acetyltransferase (GNAT) domain
LKAIADJA_02661 6.2e-182 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
LKAIADJA_02662 1.2e-97 ydhK M Protein of unknown function (DUF1541)
LKAIADJA_02663 4.6e-200 pbuE EGP Major facilitator Superfamily
LKAIADJA_02664 1.2e-46 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
LKAIADJA_02665 5.6e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
LKAIADJA_02666 2.6e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LKAIADJA_02667 8.1e-284 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LKAIADJA_02668 4.3e-132 ydhQ K UTRA
LKAIADJA_02669 4.4e-166 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
LKAIADJA_02670 2.5e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
LKAIADJA_02671 3.8e-212 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
LKAIADJA_02672 6.1e-157 ydhU P Catalase
LKAIADJA_02675 8.4e-119 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LKAIADJA_02676 4.9e-153 ytmP 2.7.1.89 M choline kinase involved in LPS biosynthesis
LKAIADJA_02677 3.6e-154 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
LKAIADJA_02678 7.7e-266 pepV 3.5.1.18 E Dipeptidase
LKAIADJA_02679 1.7e-29
LKAIADJA_02680 1.1e-119 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LKAIADJA_02681 2.5e-292 ytgP S Polysaccharide biosynthesis protein
LKAIADJA_02682 2.7e-206 ytfP S HI0933-like protein
LKAIADJA_02683 2.4e-50 ytwF P Rhodanese Homology Domain
LKAIADJA_02684 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
LKAIADJA_02685 1.1e-212 yttB EGP Major facilitator Superfamily
LKAIADJA_02686 4.3e-188 yhcC S radical SAM protein
LKAIADJA_02687 9.7e-95 noeI M Putative rRNA methylase
LKAIADJA_02688 1.6e-62 rot 2.7.1.83 K Global regulator with both positive and negative effects that mediates modulation of several genes involved in virulence
LKAIADJA_02689 5.5e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
LKAIADJA_02690 2.9e-148 ytpA 3.1.1.5 I Lysophospholipase
LKAIADJA_02691 1.7e-182 putA E Proline dehydrogenase
LKAIADJA_02692 3.7e-76 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
LKAIADJA_02693 5e-210 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LKAIADJA_02694 1.4e-105 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H riboflavin synthase alpha
LKAIADJA_02695 1.6e-188 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LKAIADJA_02696 1.3e-271 S FAD-NAD(P)-binding
LKAIADJA_02697 6.4e-160 opuCC M Amino acid ABC transporter amino acid-binding protein
LKAIADJA_02698 8.2e-146 lytD 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LKAIADJA_02699 2.6e-35
LKAIADJA_02700 8.1e-66 sigS 2.7.7.6 K Belongs to the sigma-70 factor family
LKAIADJA_02701 4e-69 S ComK protein
LKAIADJA_02702 5.1e-62
LKAIADJA_02703 1.6e-123 tal 2.2.1.2 H Transaldolase
LKAIADJA_02704 5.5e-36
LKAIADJA_02705 1.3e-47 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LKAIADJA_02706 1.2e-18 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LKAIADJA_02707 3.6e-138 ytbE S aldo keto reductase
LKAIADJA_02708 7e-111 S Nuclease-related domain
LKAIADJA_02709 3.6e-224 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LKAIADJA_02710 7.7e-307 pckA 4.1.1.49 F Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LKAIADJA_02711 1.6e-138 ytmA E Prolyl oligopeptidase family
LKAIADJA_02712 1.4e-76 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
LKAIADJA_02713 3.1e-34 yidD S Could be involved in insertion of integral membrane proteins into the membrane
LKAIADJA_02714 1e-158 menC 4.2.1.113, 5.1.1.20, 5.1.1.3 M Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
LKAIADJA_02715 9.6e-237 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
LKAIADJA_02716 1.9e-22
LKAIADJA_02725 3.9e-80 ydeN S Serine hydrolase
LKAIADJA_02726 1.4e-256 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LKAIADJA_02727 1.1e-177 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
LKAIADJA_02728 1e-190 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LKAIADJA_02729 3.8e-90 traP 1.14.99.57, 6.2.1.3 S Signal transduction protein
LKAIADJA_02730 3.8e-205 ecsB U ABC transporter
LKAIADJA_02731 1.2e-132 ecsA V ABC transporter, ATP-binding protein
LKAIADJA_02732 7.9e-73 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
LKAIADJA_02733 1.2e-19 yhaH S gas vesicle protein
LKAIADJA_02734 1.5e-90 yhaK S Putative zincin peptidase
LKAIADJA_02735 2.3e-123 prsA 5.2.1.8 M peptidyl-prolyl isomerase
LKAIADJA_02736 3.4e-177 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
LKAIADJA_02737 0.0 yhaN D AAA domain
LKAIADJA_02738 9.1e-220 yhaO L DNA repair exonuclease
LKAIADJA_02739 1.8e-51 yheA S Belongs to the UPF0342 family
LKAIADJA_02740 1.3e-191 yheB S Belongs to the UPF0754 family
LKAIADJA_02741 4.9e-84 K Helix-turn-helix XRE-family like proteins
LKAIADJA_02742 4.6e-157 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
LKAIADJA_02743 0.0 pflB 2.3.1.54 C formate C-acetyltransferase activity
LKAIADJA_02744 1.2e-135 pflA 1.97.1.4 H Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LKAIADJA_02745 4e-42
LKAIADJA_02746 4.9e-195 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LKAIADJA_02747 4.6e-106 yhcZ K response regulator
LKAIADJA_02748 1.8e-201 yhcY 2.7.13.3 T Histidine kinase
LKAIADJA_02749 2.7e-141 rluA 5.4.99.23 J Pseudouridine synthase
LKAIADJA_02751 2.2e-265 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LKAIADJA_02752 3.5e-62
LKAIADJA_02753 3.4e-20
LKAIADJA_02754 6.9e-107 nagB 3.1.1.31, 3.5.99.6 G Glucosamine-6-phosphate isomerase
LKAIADJA_02755 5.8e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LKAIADJA_02756 9e-217 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LKAIADJA_02757 3.7e-123 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
LKAIADJA_02758 2e-256 arpJ P ABC transporter
LKAIADJA_02759 5.1e-177 pfoS S Phosphotransferase system, EIIC
LKAIADJA_02769 1e-07
LKAIADJA_02773 1.6e-07
LKAIADJA_02774 3.3e-08
LKAIADJA_02780 1.2e-66 ywnB S NAD(P)H-binding
LKAIADJA_02783 8.8e-30 fliF 2.1.1.72 N bacterial-type flagellum-dependent cell motility
LKAIADJA_02784 1.7e-48 EGP Major Facilitator Superfamily
LKAIADJA_02785 1e-146
LKAIADJA_02786 1.9e-167 acmB 3.2.1.96, 3.5.1.28 CBM50 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LKAIADJA_02787 1.9e-292 pip GM Phage infection protein
LKAIADJA_02788 1.5e-177 O Trypsin
LKAIADJA_02789 5.9e-128 ymaC S Pfam:DUF867
LKAIADJA_02790 4e-182 G Acyltransferase family
LKAIADJA_02791 1.2e-293 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LKAIADJA_02792 1.3e-74 I Acyltransferase family
LKAIADJA_02793 7.3e-60 4.1.1.44 S Carboxymuconolactone decarboxylase family
LKAIADJA_02794 4.7e-112 K Transcriptional regulator
LKAIADJA_02795 5.9e-117 1.1.1.31, 1.1.1.60 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
LKAIADJA_02796 2.7e-94 EGP Sugar (and other) transporter
LKAIADJA_02797 1.4e-72 S LPXTG cell wall anchor motif
LKAIADJA_02798 8.8e-143 ykuT M Mechanosensitive ion channel
LKAIADJA_02799 2.4e-130 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
LKAIADJA_02800 1.4e-72 yqjI K Transcriptional regulator PadR-like family
LKAIADJA_02801 3.1e-172 CH FAD binding domain
LKAIADJA_02802 3.6e-127 ybbH K Helix-turn-helix domain, rpiR family
LKAIADJA_02803 2.2e-45 celA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
LKAIADJA_02804 7.6e-228 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LKAIADJA_02805 1.2e-46 celC 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
LKAIADJA_02807 2.5e-200 S Bacterial protein of unknown function (DUF871)
LKAIADJA_02808 1.2e-92 yogA 1.1.1.1 C Zinc-binding dehydrogenase
LKAIADJA_02809 3.5e-155 ycbJ S Phosphotransferase enzyme family
LKAIADJA_02810 4.9e-87 K Bacterial regulatory helix-turn-helix protein, lysR family
LKAIADJA_02811 4.7e-157 EGP Major Facilitator Superfamily
LKAIADJA_02812 4.4e-83 2.1.1.265 K Helix-turn-helix XRE-family like proteins
LKAIADJA_02813 4e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LKAIADJA_02814 2.1e-119
LKAIADJA_02815 7.6e-10 S Cupin
LKAIADJA_02816 4.6e-37 S Cupin
LKAIADJA_02817 1.1e-170 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LKAIADJA_02818 6.4e-167 3.1.1.81 S Metallo-beta-lactamase superfamily
LKAIADJA_02819 2.4e-209 adhC 1.1.1.1 C Alcohol dehydrogenase GroES-like domain
LKAIADJA_02820 9.6e-224 yflS P Sodium:sulfate symporter transmembrane region
LKAIADJA_02821 7.6e-106 IQ KR domain
LKAIADJA_02822 3.2e-135 czcD P Co Zn Cd efflux system component
LKAIADJA_02823 2.1e-146 glcT K antiterminator
LKAIADJA_02824 0.0 ptsG 2.7.1.193, 2.7.1.199 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in
LKAIADJA_02825 1.4e-145 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LKAIADJA_02826 1.4e-139 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
LKAIADJA_02827 1.8e-268 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
LKAIADJA_02828 1.4e-108 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
LKAIADJA_02829 2.6e-198 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
LKAIADJA_02830 6.5e-99 codA 3.5.4.1, 3.5.4.21 F Amidohydrolase family
LKAIADJA_02831 5.1e-107 codA 3.5.4.1, 3.5.4.21 F Amidohydrolase family
LKAIADJA_02832 1.1e-48 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
LKAIADJA_02833 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
LKAIADJA_02834 1.7e-54 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
LKAIADJA_02835 1.3e-111 K Transcriptional regulator
LKAIADJA_02836 6.4e-219 V ABC-2 family transporter protein
LKAIADJA_02837 4.4e-120 msmR K Lactose operon transcription activator
LKAIADJA_02838 1.1e-229 lacP G MFS/sugar transport protein
LKAIADJA_02839 0.0 lacZ 3.2.1.23 G Beta galactosidase small chain
LKAIADJA_02840 1.5e-295 S Predicted ATPase of the ABC class
LKAIADJA_02841 8.5e-28 K Cro/C1-type HTH DNA-binding domain
LKAIADJA_02842 5.7e-83 S Protein of unknown function (DUF2975)
LKAIADJA_02843 5.6e-09 S Protein of unknown function (DUF2648)
LKAIADJA_02844 8.9e-289 mqo 1.1.5.4 C malate quinone oxidoreductase
LKAIADJA_02845 7.9e-140 IQ KR domain
LKAIADJA_02846 4.3e-254 ybhI P Sodium:sulfate symporter transmembrane region
LKAIADJA_02847 2e-75 yfiT S DinB superfamily
LKAIADJA_02848 7.7e-51 mltD 3.5.1.28 CBM50 M Is able to cleave peptidoglycan and affects clumping and separation of bacterial cells
LKAIADJA_02849 4.1e-116 rluC 5.4.99.23, 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
LKAIADJA_02850 5.2e-53 sceD M Is able to cleave peptidoglycan and affects clumping and separation of bacterial cells
LKAIADJA_02851 3.9e-47 sceD M Is able to cleave peptidoglycan and affects clumping and separation of bacterial cells
LKAIADJA_02852 4.1e-142 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LKAIADJA_02853 1.1e-58 S Membrane transport protein
LKAIADJA_02854 5.5e-183 yceA S Belongs to the UPF0176 family
LKAIADJA_02855 1.5e-27
LKAIADJA_02856 2.7e-82 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LKAIADJA_02857 2.6e-197 yhgE GM Phage infection protein
LKAIADJA_02858 1.9e-69 K helix_turn_helix multiple antibiotic resistance protein
LKAIADJA_02859 8.3e-86 S Protein of unknown function (DUF4064)
LKAIADJA_02860 4.1e-142 K Helix-turn-helix domain
LKAIADJA_02862 2.2e-152 S Membrane transport protein
LKAIADJA_02863 7.3e-259 xylB 2.7.1.17 G xylulose kinase
LKAIADJA_02864 2.7e-95 thiE2 2.5.1.3, 5.3.99.10 H Thiamine monophosphate synthase
LKAIADJA_02865 3e-30 thiS 2.5.1.3, 2.8.1.10 H Thiamine biosynthesis protein ThiS
LKAIADJA_02866 3.3e-138 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
LKAIADJA_02867 8.1e-177 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LKAIADJA_02868 0.0 nrdD 1.1.98.6 F ribonucleoside-triphosphate reductase
LKAIADJA_02869 4e-98 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LKAIADJA_02870 8.2e-182 pva3 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
LKAIADJA_02871 7.2e-117 D LPXTG cell wall anchor motif
LKAIADJA_02872 6.4e-157 EGP Major facilitator Superfamily
LKAIADJA_02873 1.9e-186 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LKAIADJA_02874 1.5e-185 ynfM EGP Major facilitator Superfamily
LKAIADJA_02875 2.3e-75
LKAIADJA_02876 1.6e-26 S Protein of unknown function (DUF4064)
LKAIADJA_02877 1e-71 lytM 3.4.24.75 M Peptidoglycan hydrolase
LKAIADJA_02878 4.6e-124 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LKAIADJA_02879 3.1e-69 arr S Rifampin ADP-ribosyl transferase
LKAIADJA_02880 1.3e-147 shetA P Voltage-dependent anion channel
LKAIADJA_02881 1.4e-101 patB 4.4.1.8 E Aminotransferase class I and II
LKAIADJA_02882 9.7e-101 patB 4.4.1.8 E Aminotransferase class I and II
LKAIADJA_02883 1.3e-76 petP K MarR family
LKAIADJA_02884 2.8e-299 ipdC 4.1.1.74 GH Belongs to the TPP enzyme family
LKAIADJA_02885 1.2e-272 aldA 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
LKAIADJA_02886 2.4e-215 baiH C flavin oxidoreductase
LKAIADJA_02887 1.1e-176 C Luciferase-like monooxygenase
LKAIADJA_02888 7.1e-53 gcdH E Glycine cleavage H-protein
LKAIADJA_02889 1.1e-141 ymdB S Appr-1'-p processing enzyme
LKAIADJA_02890 2e-163 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
LKAIADJA_02891 2.8e-185 lplA 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
LKAIADJA_02892 8.8e-176 S Oxidoreductase family, NAD-binding Rossmann fold
LKAIADJA_02893 5.4e-207 S Putative glycosyl hydrolase domain
LKAIADJA_02894 1.5e-118 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
LKAIADJA_02895 1.5e-78 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
LKAIADJA_02896 3e-131 cpmA S AIR carboxylase
LKAIADJA_02897 7.1e-139 larE S NAD synthase
LKAIADJA_02898 4.3e-236 larA 5.1.2.1 S Domain of unknown function (DUF2088)
LKAIADJA_02899 2.5e-193 P 2-keto-3-deoxygluconate permease
LKAIADJA_02900 3.9e-204 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
LKAIADJA_02901 5.3e-182 KT Putative sugar diacid recognition
LKAIADJA_02902 0.0 ppdK 2.7.9.1 G Belongs to the PEP-utilizing enzyme family
LKAIADJA_02903 3e-145 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
LKAIADJA_02904 1.2e-70 S 3-demethylubiquinone-9 3-methyltransferase
LKAIADJA_02905 5e-82
LKAIADJA_02906 1.9e-81
LKAIADJA_02907 2.7e-97 ydcN K Cupin domain
LKAIADJA_02908 5.3e-99 yeaN P transporter
LKAIADJA_02909 1.6e-86 yeaN P transporter
LKAIADJA_02910 1.4e-262 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LKAIADJA_02911 2.2e-227 gabR K helix_turn_helix gluconate operon transcriptional repressor
LKAIADJA_02912 3.5e-236 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LKAIADJA_02913 4.1e-248 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
LKAIADJA_02914 1e-246 yhdG E Amino acid permease
LKAIADJA_02915 5e-158 S Phosphotransferase system, EIIC
LKAIADJA_02916 3.6e-160 fda 4.1.2.13 G Belongs to the class I fructose-bisphosphate aldolase family
LKAIADJA_02917 1.1e-122 ycgJ Q Methionine biosynthesis protein MetW
LKAIADJA_02918 1.4e-300 cudT M Belongs to the BCCT transporter (TC 2.A.15) family
LKAIADJA_02919 2.7e-97 yuaC K Belongs to the GbsR family
LKAIADJA_02920 1.4e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
LKAIADJA_02921 0.0 betA 1.1.99.1 E Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
LKAIADJA_02922 0.0 tagF 2.7.8.12 M teichoic acid biosynthesis
LKAIADJA_02923 1.5e-112 drgA C nitroreductase
LKAIADJA_02924 2e-184 capA M Bacterial capsule synthesis protein PGA_cap
LKAIADJA_02925 6.6e-173 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
LKAIADJA_02926 7.1e-251 proP EGP proline betaine transporter
LKAIADJA_02927 1.7e-178
LKAIADJA_02928 1.4e-191 S ABC-2 family transporter protein
LKAIADJA_02929 6e-142
LKAIADJA_02930 7.1e-113 V ABC transporter, ATP-binding protein
LKAIADJA_02931 1.3e-42 gntP EG to gi 22127301 ref NP_670724.1 Yersinia pestis KIM , percent identity
LKAIADJA_02932 2.6e-66 gntP EG to gi 22127301 ref NP_670724.1 Yersinia pestis KIM , percent identity
LKAIADJA_02933 1.7e-55 gntP EG to gi 22127301 ref NP_670724.1 Yersinia pestis KIM , percent identity
LKAIADJA_02934 6.6e-218 rocD1 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
LKAIADJA_02935 4.1e-184 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LKAIADJA_02936 4.2e-215 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LKAIADJA_02937 1.3e-102 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
LKAIADJA_02938 4.3e-220 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
LKAIADJA_02939 2.3e-93 ssuE 1.5.1.38 S NADPH-dependent FMN reductase
LKAIADJA_02940 4e-116 E Ring-cleavage extradiol dioxygenase
LKAIADJA_02941 1.4e-96 K helix_turn_helix isocitrate lyase regulation
LKAIADJA_02942 8.7e-190 gntP EG Gluconate
LKAIADJA_02943 3.8e-150 idnD 1.1.1.264 E Alcohol dehydrogenase GroES-like domain
LKAIADJA_02944 3.4e-270 lldP C L-lactate permease
LKAIADJA_02945 1.7e-235 yoaB EGP Major facilitator Superfamily
LKAIADJA_02946 1.8e-157 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LKAIADJA_02947 7.8e-280 ptsG 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
LKAIADJA_02948 3.8e-126 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LKAIADJA_02950 7e-199 nupC F Na+ dependent nucleoside transporter C-terminus
LKAIADJA_02951 1.9e-161 psuG 4.2.1.70 Q Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway
LKAIADJA_02952 3.9e-204 yeiI 2.7.1.15, 2.7.1.45, 2.7.1.83 GK pfkB family carbohydrate kinase
LKAIADJA_02953 4.6e-37 S mRNA processing
LKAIADJA_02954 2.7e-209 yvbJ S zinc-ribbon domain
LKAIADJA_02955 3.5e-85 yebC M zinc-ribbon domain
LKAIADJA_02956 1.5e-158 O peptidase U32
LKAIADJA_02957 0.0 2.7.1.202 G Mga helix-turn-helix domain
LKAIADJA_02958 2.1e-68 ulaC 2.7.1.194, 2.7.1.197, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LKAIADJA_02959 1.5e-43 ulaB 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
LKAIADJA_02960 1.7e-217 ulaA 2.7.1.194 S PTS system sugar-specific permease component
LKAIADJA_02961 4.9e-140 MA20_19915 Q Thioesterase-like superfamily
LKAIADJA_02962 6.5e-165 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LKAIADJA_02963 9.6e-91 GM RmlD substrate binding domain
LKAIADJA_02964 2.8e-125 fecB P ABC transporter
LKAIADJA_02965 3.5e-146 metQ P Belongs to the NlpA lipoprotein family
LKAIADJA_02966 2.5e-164 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
LKAIADJA_02967 9e-230 mga 1.1.1.17, 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LKAIADJA_02968 1.3e-260 manP 2.7.1.191, 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LKAIADJA_02969 1.2e-166 manA 5.3.1.8 G mannose-6-phosphate isomerase
LKAIADJA_02970 1.4e-156 glcK 2.7.1.2 GK ROK family
LKAIADJA_02971 1.7e-65 S Putative threonine/serine exporter
LKAIADJA_02972 1.5e-133 thrE S Putative threonine/serine exporter
LKAIADJA_02973 1.8e-237 metY 2.5.1.49 E O-acetylhomoserine
LKAIADJA_02974 2.5e-212 EGP Major facilitator Superfamily
LKAIADJA_02975 9e-101 K Bacterial regulatory proteins, tetR family
LKAIADJA_02976 1.2e-121 ybhF_2 V ABC transporter, ATP-binding protein
LKAIADJA_02977 1.1e-185 ybhR V ABC-2 family transporter protein
LKAIADJA_02978 4.5e-104 ycfA K Bacterial regulatory proteins, tetR family
LKAIADJA_02979 1.3e-81 fcbC S Thioesterase-like superfamily
LKAIADJA_02980 1.3e-191 S membrane
LKAIADJA_02981 9.6e-16
LKAIADJA_02982 8.4e-151 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
LKAIADJA_02983 2.3e-110 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LKAIADJA_02984 4.9e-125 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
LKAIADJA_02985 2.3e-78 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
LKAIADJA_02986 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
LKAIADJA_02987 3.1e-66 ureB 3.5.1.5 E Belongs to the urease beta subunit family
LKAIADJA_02988 9e-47 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
LKAIADJA_02989 1.5e-142 yut E urea transporter
LKAIADJA_02990 1.9e-259 E ABC transporter substrate-binding protein
LKAIADJA_02991 2.7e-148 dppB2 P permease
LKAIADJA_02992 2.8e-119 nikC EP permease
LKAIADJA_02993 2.8e-132 oppD EP ABC-type dipeptide oligopeptide nickel transport system
LKAIADJA_02994 2e-113 oppF7 3.6.3.24 E ABC-type oligopeptide transport system, ATPase component
LKAIADJA_02995 1.9e-164 fhuD P Ferrichrome ABC transporter substrate-binding protein
LKAIADJA_02996 1.1e-58 K Winged helix DNA-binding domain
LKAIADJA_02997 5.1e-39 S member of glyoxalase bleomycin resistance protein family
LKAIADJA_02998 1.4e-131 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
LKAIADJA_02999 5.3e-69 T Belongs to the universal stress protein A family
LKAIADJA_03000 7.8e-186 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
LKAIADJA_03001 1.6e-152 yniA G Fructosamine kinase
LKAIADJA_03002 2.8e-32 Z012_10635 S UPF0291 protein
LKAIADJA_03003 2.9e-179 luxA_2 C Luciferase-like monooxygenase
LKAIADJA_03004 5e-118 gseA 3.4.21.19 E Peptidase S46
LKAIADJA_03005 6.8e-88 tetR K Bacterial regulatory proteins, tetR family
LKAIADJA_03006 1.1e-146 yjlA EG Putative multidrug resistance efflux transporter
LKAIADJA_03007 1.3e-165 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
LKAIADJA_03008 2.4e-93 lytM M COG0739 Membrane proteins related to metalloendopeptidases
LKAIADJA_03009 1.9e-105 tag 3.2.2.21 L endonuclease III
LKAIADJA_03010 8.6e-57 yeaO S Protein of unknown function, DUF488
LKAIADJA_03011 4.4e-71 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
LKAIADJA_03012 4.8e-161 pfoS S Phosphotransferase system, EIIC
LKAIADJA_03013 1.3e-91 isaA M Is able to cleave peptidoglycan and affects clumping and separation of bacterial cells
LKAIADJA_03014 1.1e-220 mtnE 2.6.1.83 E Aminotransferase
LKAIADJA_03015 1.4e-176 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LKAIADJA_03016 4.4e-29 copZ P copper chaperone
LKAIADJA_03017 0.0 copA 3.6.3.54 P P-type ATPase
LKAIADJA_03018 5.9e-245 P Sulfate permease
LKAIADJA_03019 7.6e-135 bceA V ABC transporter, ATP-binding protein
LKAIADJA_03020 1.6e-303 bceB V ABC transporter (permease)
LKAIADJA_03021 6.6e-151 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKAIADJA_03022 2.6e-29
LKAIADJA_03023 7.5e-245 sdcS P Sodium:sulfate symporter transmembrane region
LKAIADJA_03024 2.5e-201 yjcL S Protein of unknown function (DUF819)
LKAIADJA_03025 9e-64 maa 2.3.1.18, 2.3.1.79 S Hexapeptide repeat of succinyl-transferase
LKAIADJA_03026 1.4e-173 pfoR G Phosphotransferase system, EIIC
LKAIADJA_03027 2e-146 ycsI S Belongs to the D-glutamate cyclase family
LKAIADJA_03028 6.8e-293 betT M Belongs to the BCCT transporter (TC 2.A.15) family
LKAIADJA_03029 4.8e-57 S Protein of unknown function (DUF4064)
LKAIADJA_03030 1.7e-295 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family
LKAIADJA_03031 1.9e-90 K Transcriptional regulator
LKAIADJA_03032 0.0 ydfJ S of the RND superfamily
LKAIADJA_03033 0.0 K helix_turn_helix, arabinose operon control protein
LKAIADJA_03034 7.7e-242 norB G Major Facilitator Superfamily
LKAIADJA_03035 8.2e-221 amd E Metal-dependent amidase aminoacylase carboxypeptidase
LKAIADJA_03036 3.6e-71
LKAIADJA_03037 1.3e-69 ybbA S Putative esterase
LKAIADJA_03038 9.3e-219 norB G Major Facilitator Superfamily
LKAIADJA_03039 9.9e-97 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LKAIADJA_03040 7.4e-286 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
LKAIADJA_03041 1.4e-217 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
LKAIADJA_03042 4.2e-201 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
LKAIADJA_03043 2.3e-224 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
LKAIADJA_03044 2.4e-186 drp35 3.1.1.17 G Exhibits lactonase activity. Acts in cells with perturbed membrane integrity and is possibly related to the membrane homeostasis (By similarity)
LKAIADJA_03045 6.3e-247 nhaC C Na H antiporter
LKAIADJA_03046 4.2e-161 ywbI K Transcriptional regulator
LKAIADJA_03047 2.6e-54 cidA S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidAB proteins. When a cell is stressed by the addition of antibiotics or by other factors in the environment, the CidAB proteins possibly oligomerize within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
LKAIADJA_03048 1.3e-109 cidB M Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidAB proteins. When a cell is stressed by the addition of antibiotics or by other factors in the environment, the CidAB proteins possibly oligomerize within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
LKAIADJA_03049 0.0 poxB 1.2.3.3, 1.2.5.1 C Belongs to the TPP enzyme family
LKAIADJA_03050 1e-246 S C4-dicarboxylate anaerobic carrier
LKAIADJA_03051 1e-91 J Acetyltransferase (GNAT) domain
LKAIADJA_03052 4.6e-91 5.1.3.33 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LKAIADJA_03053 5.7e-175 4.4.1.15 E Pyridoxal-phosphate dependent enzyme
LKAIADJA_03054 5e-51 traF CO Thioredoxin
LKAIADJA_03055 6.7e-90 yhhY 2.1.2.9 M Acetyltransferase (GNAT) domain
LKAIADJA_03056 2.7e-145 I Steryl acetyl hydrolase
LKAIADJA_03057 4.7e-213 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
LKAIADJA_03058 2.7e-44
LKAIADJA_03059 4.4e-219 murD 6.3.2.9 M Mur ligase middle domain
LKAIADJA_03060 7.1e-72 pgsC S Capsule biosynthesis CapC
LKAIADJA_03061 1.3e-193 capA M Bacterial capsule synthesis protein PGA_cap
LKAIADJA_03062 2.9e-20
LKAIADJA_03063 1.1e-292 2.3.2.2, 3.4.19.13 E Gamma-glutamyltranspeptidase
LKAIADJA_03064 2.5e-187 S membrane
LKAIADJA_03065 4.9e-254 gabT 2.6.1.19, 5.1.1.21 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LKAIADJA_03066 3.7e-89 S Hypothetical bacterial integral membrane protein (Trep_Strep)
LKAIADJA_03067 1.2e-110 P Cobalt transport protein
LKAIADJA_03068 3e-273 G AAA domain, putative AbiEii toxin, Type IV TA system
LKAIADJA_03069 0.0 K helix_turn_helix, arabinose operon control protein
LKAIADJA_03070 2e-186 K helix_turn _helix lactose operon repressor
LKAIADJA_03071 2.4e-189 EGP Major facilitator Superfamily
LKAIADJA_03072 2.8e-290 xylB 2.7.1.17 G xylulose kinase
LKAIADJA_03073 5e-201 gutB 1.1.1.14 E Glucose dehydrogenase C-terminus
LKAIADJA_03075 7e-124 dhlB 3.8.1.2 S Haloacid dehalogenase-like hydrolase
LKAIADJA_03076 7.6e-219 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
LKAIADJA_03077 1.6e-108 srtA 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
LKAIADJA_03078 1.5e-118 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
LKAIADJA_03079 1.8e-142 K Transcriptional regulator
LKAIADJA_03080 1.6e-160 nanK GK ROK family
LKAIADJA_03081 6.1e-160 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
LKAIADJA_03082 2.2e-229 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LKAIADJA_03083 1.6e-143 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
LKAIADJA_03084 1.5e-118 frp C nitroreductase
LKAIADJA_03085 3e-153 1.13.11.2 S Glyoxalase bleomycin resistance protein dioxygenase superfamily protein
LKAIADJA_03086 3.5e-271 mdlA V COG1132 ABC-type multidrug transport system, ATPase and permease components
LKAIADJA_03087 0.0 mdlB V COG1132 ABC-type multidrug transport system, ATPase and permease components
LKAIADJA_03088 1.4e-46 yjdJ S GCN5-related N-acetyl-transferase
LKAIADJA_03089 2e-164 adcA P Belongs to the bacterial solute-binding protein 9 family
LKAIADJA_03090 1.9e-227 aldA 1.2.1.21, 1.2.1.22 C Belongs to the aldehyde dehydrogenase family
LKAIADJA_03091 2.4e-72 K helix_turn_helix multiple antibiotic resistance protein
LKAIADJA_03092 4.9e-187 mhqA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LKAIADJA_03093 1.4e-175 mhqO E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LKAIADJA_03094 2.8e-108 mhqD S Phospholipase/Carboxylesterase
LKAIADJA_03095 4.9e-180 S Membrane
LKAIADJA_03096 0.0 fbp 3.1.3.11 G D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
LKAIADJA_03097 2.4e-281 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LKAIADJA_03098 5.8e-85 dedA 3.1.3.1 S SNARE associated Golgi protein
LKAIADJA_03099 5e-89 G Major facilitator
LKAIADJA_03100 3.6e-107 G Major Facilitator Superfamily
LKAIADJA_03101 8.8e-44 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
LKAIADJA_03103 6.1e-131 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
LKAIADJA_03104 0.0 S Fusaric acid resistance protein-like
LKAIADJA_03105 2.2e-168 S conserved protein (DUF2267)
LKAIADJA_03106 4.5e-219 S conserved protein (DUF2267)
LKAIADJA_03107 1.1e-71 S Uncharacterized protein conserved in bacteria (DUF2188)
LKAIADJA_03108 7.2e-124 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
LKAIADJA_03109 1.7e-128 K MerR family regulatory protein
LKAIADJA_03110 8.4e-125 gntR K Gluconate operon transcriptional repressor
LKAIADJA_03111 2e-299 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
LKAIADJA_03112 1.8e-216 gntP EG Gluconate
LKAIADJA_03113 5.2e-174 S membrane
LKAIADJA_03114 1.2e-222 K helix_turn_helix, arabinose operon control protein
LKAIADJA_03115 9.7e-253 yjmB G MFS/sugar transport protein
LKAIADJA_03116 0.0 uidA 3.2.1.31 G Belongs to the glycosyl hydrolase 2 family
LKAIADJA_03117 0.0 nag3 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
LKAIADJA_03118 2.6e-160 S Haloacid dehalogenase-like hydrolase
LKAIADJA_03119 6e-117 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
LKAIADJA_03120 5.9e-28
LKAIADJA_03121 7.8e-42 S Domain of unknown function (DUF1413)
LKAIADJA_03122 6.2e-123 sdh S Belongs to the short-chain dehydrogenases reductases (SDR) family
LKAIADJA_03123 6e-51 K FR47-like protein
LKAIADJA_03124 1.5e-25 K FR47-like protein
LKAIADJA_03125 2.9e-116 hisE 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Histidine biosynthesis bifunctional protein hisIE
LKAIADJA_03126 3.4e-143 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
LKAIADJA_03127 5e-133 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LKAIADJA_03128 1.9e-106 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LKAIADJA_03129 7.6e-103 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
LKAIADJA_03130 1.1e-186 hisC 2.6.1.9 E COG0079 Histidinol-phosphate aromatic aminotransferase and cobyric acid decarboxylase
LKAIADJA_03131 2.6e-236 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LKAIADJA_03132 3.5e-106 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
LKAIADJA_03133 4.6e-154 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LKAIADJA_03134 1.5e-252 dsdA 4.3.1.18 E Pyridoxal-phosphate dependent enzyme
LKAIADJA_03135 7.8e-08
LKAIADJA_03144 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LKAIADJA_03145 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LKAIADJA_03146 1.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
LKAIADJA_03147 5.4e-283 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
LKAIADJA_03148 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
LKAIADJA_03149 9.9e-77 tspO T membrane
LKAIADJA_03150 1.1e-203 cotI S Spore coat protein
LKAIADJA_03151 7.2e-214 cotSA M Glycosyl transferases group 1
LKAIADJA_03152 2.8e-204 cotS S Seems to be required for the assembly of the CotSA protein in spores
LKAIADJA_03154 1.8e-226 ytcC M Glycosyltransferase Family 4
LKAIADJA_03155 2.9e-176 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
LKAIADJA_03156 1.7e-243 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LKAIADJA_03157 5.6e-152 galU 2.7.7.9 M Nucleotidyl transferase
LKAIADJA_03158 7.4e-132 dksA T COG1734 DnaK suppressor protein
LKAIADJA_03159 2.7e-271 menF 5.4.4.2 HQ Isochorismate synthase
LKAIADJA_03160 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LKAIADJA_03161 1.7e-151 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
LKAIADJA_03162 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LKAIADJA_03163 2.8e-271 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
LKAIADJA_03164 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
LKAIADJA_03165 1.1e-169 troA P Belongs to the bacterial solute-binding protein 9 family
LKAIADJA_03166 4.5e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
LKAIADJA_03167 1.8e-229 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
LKAIADJA_03168 2.6e-150 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
LKAIADJA_03169 4.3e-24 S Domain of Unknown Function (DUF1540)
LKAIADJA_03170 4e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
LKAIADJA_03171 2.3e-248 cydA 1.10.3.14 C oxidase, subunit
LKAIADJA_03172 3.6e-41 rpmE2 J Ribosomal protein L31
LKAIADJA_03173 9.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
LKAIADJA_03174 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LKAIADJA_03175 1.1e-72 ytkA S YtkA-like
LKAIADJA_03177 1e-75 dps P Belongs to the Dps family
LKAIADJA_03178 1.1e-60 ytkC S Bacteriophage holin family
LKAIADJA_03179 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
LKAIADJA_03180 1.5e-141 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
LKAIADJA_03181 1.4e-144 ytlC P ABC transporter
LKAIADJA_03182 9.5e-189 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
LKAIADJA_03183 1.1e-146 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
LKAIADJA_03184 1.6e-38 ytmB S Protein of unknown function (DUF2584)
LKAIADJA_03185 9.7e-310 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LKAIADJA_03186 4.7e-224 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LKAIADJA_03187 0.0 asnB 6.3.5.4 E Asparagine synthase
LKAIADJA_03188 1.7e-254 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
LKAIADJA_03189 2.7e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LKAIADJA_03190 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
LKAIADJA_03191 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
LKAIADJA_03192 3.3e-106 ytqB J Putative rRNA methylase
LKAIADJA_03193 1.8e-189 yhcC S Fe-S oxidoreductase
LKAIADJA_03194 1.5e-40 ytzC S Protein of unknown function (DUF2524)
LKAIADJA_03196 5.1e-66 ytrA K GntR family transcriptional regulator
LKAIADJA_03197 4.2e-161 ytrB P abc transporter atp-binding protein
LKAIADJA_03198 4.7e-153 P ABC-2 family transporter protein
LKAIADJA_03199 1.9e-146
LKAIADJA_03200 9.1e-127 ytrE V ABC transporter, ATP-binding protein
LKAIADJA_03201 1.8e-232 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
LKAIADJA_03202 3.3e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKAIADJA_03203 4e-184 T PhoQ Sensor
LKAIADJA_03204 1.1e-138 bceA V ABC transporter, ATP-binding protein
LKAIADJA_03205 0.0 bceB V ABC transporter (permease)
LKAIADJA_03206 1.9e-42 yttA 2.7.13.3 S Pfam Transposase IS66
LKAIADJA_03207 1.3e-210 yttB EGP Major facilitator Superfamily
LKAIADJA_03208 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
LKAIADJA_03209 8.5e-54 ytvB S Protein of unknown function (DUF4257)
LKAIADJA_03210 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
LKAIADJA_03211 2.1e-51 ytwF P Sulfurtransferase
LKAIADJA_03212 5.3e-253 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
LKAIADJA_03213 2.2e-143 amyC P ABC transporter (permease)
LKAIADJA_03214 2.4e-167 amyD P ABC transporter
LKAIADJA_03215 1.5e-244 msmE G Bacterial extracellular solute-binding protein
LKAIADJA_03216 2.3e-187 msmR K Transcriptional regulator
LKAIADJA_03217 2.7e-171 ytaP S Acetyl xylan esterase (AXE1)
LKAIADJA_03218 7.2e-152 ydjN U Involved in the tonB-independent uptake of proteins
LKAIADJA_03219 4.5e-64 ydjM M Lytic transglycolase
LKAIADJA_03220 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
LKAIADJA_03221 2.7e-258 iolT EGP Major facilitator Superfamily
LKAIADJA_03222 4e-195 S Ion transport 2 domain protein
LKAIADJA_03223 4.1e-149 ydjI S virion core protein (lumpy skin disease virus)
LKAIADJA_03224 2.5e-130 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
LKAIADJA_03225 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LKAIADJA_03226 1.9e-113 pspA KT Phage shock protein A
LKAIADJA_03227 1.7e-171 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
LKAIADJA_03228 2.7e-255 gutA G MFS/sugar transport protein
LKAIADJA_03229 4.2e-200 gutB 1.1.1.14 E Dehydrogenase
LKAIADJA_03230 0.0 K NB-ARC domain
LKAIADJA_03231 3.2e-149 ydjC S Abhydrolase domain containing 18
LKAIADJA_03233 7.1e-240 3.1.21.5, 3.6.4.12 L DEAD-like helicases superfamily
LKAIADJA_03235 1.8e-13
LKAIADJA_03236 4.9e-07 S Antitoxin to bacterial toxin RNase LS or RnlA
LKAIADJA_03237 3.4e-67 rnhA 3.1.26.4 L Caulimovirus viroplasmin
LKAIADJA_03238 6.1e-27 K Helix-turn-helix domain
LKAIADJA_03239 9e-41 S protein domain associated with
LKAIADJA_03240 2.2e-103 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
LKAIADJA_03241 2.7e-31 xhlB S SPP1 phage holin
LKAIADJA_03242 9.5e-27 xhlA S Haemolysin XhlA
LKAIADJA_03247 5.2e-204 sidC L Phage minor structural protein
LKAIADJA_03248 9.9e-50
LKAIADJA_03249 3.4e-177
LKAIADJA_03250 2.4e-28 S Phage tail assembly chaperone protein, TAC
LKAIADJA_03251 2.2e-07 chiB 3.2.1.14 GH18 G Belongs to the glycosyl hydrolase 18 family
LKAIADJA_03252 1.3e-34 S Phage tail tube protein
LKAIADJA_03253 1.3e-29 S Protein of unknown function (DUF3168)
LKAIADJA_03254 5.2e-37 S Bacteriophage HK97-gp10, putative tail-component
LKAIADJA_03255 1.2e-26 S Phage head-tail joining protein
LKAIADJA_03256 1.1e-28 S Phage gp6-like head-tail connector protein
LKAIADJA_03258 1e-54 gpG
LKAIADJA_03259 5.4e-44 S Phage minor structural protein GP20
LKAIADJA_03261 4.5e-81 S Phage Mu protein F like protein
LKAIADJA_03262 1.2e-120 S Phage portal protein, SPP1 Gp6-like
LKAIADJA_03264 2.6e-196 S Phage terminase large subunit
LKAIADJA_03265 1.4e-45 L Terminase small subunit
LKAIADJA_03268 2.7e-79 L Transposase
LKAIADJA_03278 1.2e-25
LKAIADJA_03280 1.6e-18 yqaO S Phage-like element PBSX protein XtrA
LKAIADJA_03282 4e-54 S Protein of unknown function (DUF1064)
LKAIADJA_03283 1.4e-10 S YopX protein
LKAIADJA_03285 2e-80 xkdC L IstB-like ATP binding protein
LKAIADJA_03286 1.4e-45 L DnaD domain protein
LKAIADJA_03287 4.9e-135 recT L RecT family
LKAIADJA_03288 1.6e-153 yqaJ L YqaJ-like viral recombinase domain
LKAIADJA_03294 3.5e-68
LKAIADJA_03295 5e-68 S DNA binding
LKAIADJA_03296 5.3e-34
LKAIADJA_03297 1.6e-19 K Helix-turn-helix XRE-family like proteins
LKAIADJA_03298 4.2e-46 xre K Helix-turn-helix XRE-family like proteins
LKAIADJA_03299 8.9e-22 S Short C-terminal domain
LKAIADJA_03300 4.2e-49 xkdA E IrrE N-terminal-like domain
LKAIADJA_03301 9.8e-145 L Belongs to the 'phage' integrase family
LKAIADJA_03302 8.3e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LKAIADJA_03303 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LKAIADJA_03304 7.9e-129 ydiL S CAAX protease self-immunity
LKAIADJA_03305 2.9e-27 ydiK S Domain of unknown function (DUF4305)
LKAIADJA_03306 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LKAIADJA_03307 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
LKAIADJA_03308 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LKAIADJA_03309 1.6e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
LKAIADJA_03310 0.0 ydiF S ABC transporter
LKAIADJA_03311 5.2e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LKAIADJA_03312 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
LKAIADJA_03313 4.9e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
LKAIADJA_03314 2.6e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
LKAIADJA_03315 1.8e-181 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LKAIADJA_03316 1.7e-75 rimJ2 J Acetyltransferase (GNAT) domain
LKAIADJA_03318 3.9e-73
LKAIADJA_03320 1.2e-73 S response regulator aspartate phosphatase
LKAIADJA_03321 5.1e-63 S Domain of unknown function with cystatin-like fold (DUF4467)
LKAIADJA_03322 1.8e-84 yddI
LKAIADJA_03323 1.5e-186 yddH CBM50 M Lysozyme-like
LKAIADJA_03324 0.0 yddG S maturation of SSU-rRNA
LKAIADJA_03325 6.3e-51 S Domain of unknown function (DUF1874)
LKAIADJA_03326 0.0 yddE S AAA-like domain
LKAIADJA_03327 4.2e-92 yddD S TcpE family
LKAIADJA_03328 4.4e-39 yddC
LKAIADJA_03329 1.8e-166 yddB S Conjugative transposon protein TcpC
LKAIADJA_03330 1.6e-32 yddA
LKAIADJA_03332 4e-16 S Domain of Unknown Function with PDB structure (DUF3850)
LKAIADJA_03333 5.3e-203 nicK L Replication initiation factor
LKAIADJA_03334 2.4e-238 ydcQ D Ftsk spoiiie family protein
LKAIADJA_03335 1.7e-63 S Bacterial protein of unknown function (DUF961)
LKAIADJA_03337 7.8e-39
LKAIADJA_03338 3.1e-16
LKAIADJA_03339 1.4e-60 yvaO K Transcriptional
LKAIADJA_03340 3.1e-84 immA E IrrE N-terminal-like domain
LKAIADJA_03341 5e-204 L Belongs to the 'phage' integrase family
LKAIADJA_03342 9.2e-74 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
LKAIADJA_03343 3.9e-216 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LKAIADJA_03344 2.8e-52 arsR K transcriptional
LKAIADJA_03345 5.2e-45 arsR K ArsR family transcriptional regulator
LKAIADJA_03346 1.4e-200 O Pyridine nucleotide-disulphide oxidoreductase
LKAIADJA_03347 3.2e-57 2.3.1.183 M Acetyltransferase (GNAT) domain
LKAIADJA_03355 6.2e-84 ydcK S Belongs to the SprT family
LKAIADJA_03356 0.0 yhgF K COG2183 Transcriptional accessory protein
LKAIADJA_03357 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
LKAIADJA_03358 1.3e-137 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LKAIADJA_03359 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
LKAIADJA_03360 3e-51 rsbV T Belongs to the anti-sigma-factor antagonist family
LKAIADJA_03361 7.1e-189 rsbU 3.1.3.3 KT phosphatase
LKAIADJA_03362 2.9e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
LKAIADJA_03363 5.2e-57 rsbS T antagonist
LKAIADJA_03364 1.3e-143 rsbR T Positive regulator of sigma-B
LKAIADJA_03365 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
LKAIADJA_03366 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
LKAIADJA_03367 4.3e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LKAIADJA_03368 8.5e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
LKAIADJA_03369 8e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LKAIADJA_03370 6.9e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
LKAIADJA_03371 9.6e-259 ydbT S Membrane
LKAIADJA_03372 2.1e-82 ydbS S Bacterial PH domain
LKAIADJA_03373 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LKAIADJA_03374 9.6e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LKAIADJA_03375 3.9e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
LKAIADJA_03376 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
LKAIADJA_03377 2.1e-149 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LKAIADJA_03378 2.2e-07 S Fur-regulated basic protein A
LKAIADJA_03379 1.1e-18 S Fur-regulated basic protein B
LKAIADJA_03380 4.4e-219 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
LKAIADJA_03381 2.7e-52 ydbL
LKAIADJA_03382 3e-123 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LKAIADJA_03383 1.8e-170 ydbJ V ABC transporter, ATP-binding protein
LKAIADJA_03385 9.7e-181 ydbI S AI-2E family transporter
LKAIADJA_03386 3.1e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LKAIADJA_03387 1.1e-119 dctR T COG4565 Response regulator of citrate malate metabolism
LKAIADJA_03388 4.8e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
LKAIADJA_03389 3.9e-198 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
LKAIADJA_03390 1.2e-138 ydbD P Catalase
LKAIADJA_03391 2.6e-61 ydbC S Domain of unknown function (DUF4937
LKAIADJA_03392 2.6e-58 ydbB G Cupin domain
LKAIADJA_03394 2.7e-146 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
LKAIADJA_03395 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
LKAIADJA_03397 1e-224 mntH P H( )-stimulated, divalent metal cation uptake system
LKAIADJA_03398 4.7e-39
LKAIADJA_03399 2.9e-19 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
LKAIADJA_03400 2.3e-287 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
LKAIADJA_03401 5.2e-75 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
LKAIADJA_03402 0.0 ydaO E amino acid
LKAIADJA_03403 3.5e-186 ydaN S Bacterial cellulose synthase subunit
LKAIADJA_03404 1e-185 ydaN S Bacterial cellulose synthase subunit
LKAIADJA_03405 4.5e-233 ydaM M Glycosyl transferase family group 2
LKAIADJA_03406 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
LKAIADJA_03407 1.2e-89 ydaK T Diguanylate cyclase, GGDEF domain
LKAIADJA_03408 1.2e-205 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
LKAIADJA_03409 5.4e-49 srtA 3.4.22.70 M Sortase family
LKAIADJA_03410 9.2e-145 ywpD T Histidine kinase
LKAIADJA_03411 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LKAIADJA_03412 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LKAIADJA_03413 2.3e-54 S aspartate phosphatase
LKAIADJA_03414 5.3e-113 S aspartate phosphatase
LKAIADJA_03415 2.6e-141 flhP N flagellar basal body
LKAIADJA_03417 6.9e-126 flhO N flagellar basal body
LKAIADJA_03418 3.5e-180 mbl D Rod shape-determining protein
LKAIADJA_03419 3e-44 spoIIID K Stage III sporulation protein D
LKAIADJA_03420 2.1e-70 ywoH K COG1846 Transcriptional regulators
LKAIADJA_03421 2.7e-211 ywoG EGP Major facilitator Superfamily
LKAIADJA_03422 1.2e-231 ywoF P Right handed beta helix region
LKAIADJA_03423 5.2e-281 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
LKAIADJA_03424 1.6e-239 ywoD EGP Major facilitator superfamily
LKAIADJA_03425 8.9e-104 phzA Q Isochorismatase family
LKAIADJA_03426 2.2e-76
LKAIADJA_03427 2.5e-225 amt P Ammonium transporter
LKAIADJA_03428 1.6e-58 nrgB K Belongs to the P(II) protein family
LKAIADJA_03429 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
LKAIADJA_03430 5.1e-72 ywnJ S VanZ like family
LKAIADJA_03431 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
LKAIADJA_03432 2e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
LKAIADJA_03433 1.4e-10 ywnC S Family of unknown function (DUF5362)
LKAIADJA_03434 2.2e-70 ywnF S Family of unknown function (DUF5392)
LKAIADJA_03435 4.6e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LKAIADJA_03436 7.7e-143 mta K transcriptional
LKAIADJA_03437 2.6e-59 ywnC S Family of unknown function (DUF5362)
LKAIADJA_03438 1.6e-114 ywnB S NAD(P)H-binding
LKAIADJA_03439 6.3e-64 ywnA K Transcriptional regulator
LKAIADJA_03440 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
LKAIADJA_03441 3.8e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
LKAIADJA_03442 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
LKAIADJA_03443 1.1e-10 csbD K CsbD-like
LKAIADJA_03444 5.1e-84 ywmF S Peptidase M50
LKAIADJA_03445 1.3e-103 S response regulator aspartate phosphatase
LKAIADJA_03446 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LKAIADJA_03447 1.3e-145 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LKAIADJA_03448 2.7e-120 ywmD S protein containing a von Willebrand factor type A (vWA) domain
LKAIADJA_03449 3.3e-121 ywmC S protein containing a von Willebrand factor type A (vWA) domain
LKAIADJA_03450 7.5e-178 spoIID D Stage II sporulation protein D
LKAIADJA_03451 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LKAIADJA_03452 9e-133 ywmB S TATA-box binding
LKAIADJA_03453 1.3e-32 ywzB S membrane
LKAIADJA_03454 1.4e-86 ywmA
LKAIADJA_03455 8.5e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
LKAIADJA_03456 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LKAIADJA_03457 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LKAIADJA_03458 4.5e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LKAIADJA_03459 2e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LKAIADJA_03460 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LKAIADJA_03461 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LKAIADJA_03462 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
LKAIADJA_03463 2.5e-62 atpI S ATP synthase
LKAIADJA_03464 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LKAIADJA_03465 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LKAIADJA_03466 1.6e-94 ywlG S Belongs to the UPF0340 family
LKAIADJA_03467 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
LKAIADJA_03468 4e-75 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LKAIADJA_03469 1.7e-91 mntP P Probably functions as a manganese efflux pump
LKAIADJA_03470 1.3e-193 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LKAIADJA_03471 2.1e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
LKAIADJA_03472 6.1e-112 spoIIR S stage II sporulation protein R
LKAIADJA_03473 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
LKAIADJA_03475 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LKAIADJA_03476 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LKAIADJA_03477 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LKAIADJA_03478 1.2e-89 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
LKAIADJA_03479 8.6e-160 ywkB S Membrane transport protein
LKAIADJA_03480 0.0 sfcA 1.1.1.38 C malic enzyme
LKAIADJA_03481 1.6e-103 tdk 2.7.1.21 F thymidine kinase
LKAIADJA_03482 1.1e-32 rpmE J Binds the 23S rRNA
LKAIADJA_03483 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LKAIADJA_03484 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
LKAIADJA_03485 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LKAIADJA_03486 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LKAIADJA_03487 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
LKAIADJA_03488 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
LKAIADJA_03489 1.3e-90 ywjG S Domain of unknown function (DUF2529)
LKAIADJA_03490 2.5e-11 tnpIS3 L Transposase
LKAIADJA_03491 2.9e-76 ctsR K Belongs to the CtsR family
LKAIADJA_03492 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
LKAIADJA_03493 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
LKAIADJA_03494 0.0 clpC O Belongs to the ClpA ClpB family
LKAIADJA_03495 6.2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LKAIADJA_03496 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LKAIADJA_03497 1.7e-196 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
LKAIADJA_03498 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
LKAIADJA_03499 1.2e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
LKAIADJA_03500 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LKAIADJA_03501 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
LKAIADJA_03502 2.4e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
LKAIADJA_03503 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LKAIADJA_03504 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LKAIADJA_03505 1.2e-88 yacP S RNA-binding protein containing a PIN domain
LKAIADJA_03506 4.4e-115 sigH K Belongs to the sigma-70 factor family
LKAIADJA_03507 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LKAIADJA_03508 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
LKAIADJA_03509 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LKAIADJA_03510 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LKAIADJA_03511 8.7e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LKAIADJA_03512 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LKAIADJA_03513 1.2e-106 rsmC 2.1.1.172 J Methyltransferase
LKAIADJA_03514 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LKAIADJA_03515 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LKAIADJA_03516 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
LKAIADJA_03517 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LKAIADJA_03518 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LKAIADJA_03519 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LKAIADJA_03520 8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LKAIADJA_03521 1.7e-184 ybaC 3.4.11.5 S Alpha/beta hydrolase family
LKAIADJA_03522 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
LKAIADJA_03523 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LKAIADJA_03524 3e-105 rplD J Forms part of the polypeptide exit tunnel
LKAIADJA_03525 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LKAIADJA_03526 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LKAIADJA_03527 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LKAIADJA_03528 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LKAIADJA_03529 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LKAIADJA_03530 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LKAIADJA_03531 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
LKAIADJA_03532 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LKAIADJA_03533 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LKAIADJA_03534 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LKAIADJA_03535 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LKAIADJA_03536 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LKAIADJA_03537 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LKAIADJA_03538 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LKAIADJA_03539 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LKAIADJA_03540 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LKAIADJA_03541 1.9e-23 rpmD J Ribosomal protein L30
LKAIADJA_03542 1.8e-72 rplO J binds to the 23S rRNA
LKAIADJA_03543 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LKAIADJA_03544 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LKAIADJA_03545 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
LKAIADJA_03546 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LKAIADJA_03547 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
LKAIADJA_03548 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LKAIADJA_03549 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LKAIADJA_03550 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LKAIADJA_03551 3.6e-58 rplQ J Ribosomal protein L17
LKAIADJA_03552 1.9e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LKAIADJA_03553 9.7e-152 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LKAIADJA_03554 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LKAIADJA_03555 8.2e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LKAIADJA_03556 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LKAIADJA_03557 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
LKAIADJA_03558 1.2e-143 ybaJ Q Methyltransferase domain
LKAIADJA_03559 3.5e-71 ybaK S Protein of unknown function (DUF2521)
LKAIADJA_03560 2.8e-131 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LKAIADJA_03561 5.1e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
LKAIADJA_03562 1.2e-84 gerD
LKAIADJA_03563 3.9e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
LKAIADJA_03564 1.8e-139 pdaB 3.5.1.104 G Polysaccharide deacetylase
LKAIADJA_03565 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKAIADJA_03566 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
LKAIADJA_03567 2.2e-139 srfAD Q thioesterase
LKAIADJA_03568 1.4e-226 EGP Major Facilitator Superfamily
LKAIADJA_03569 2.1e-89 S YcxB-like protein
LKAIADJA_03570 1.3e-160 ycxC EG EamA-like transporter family
LKAIADJA_03571 6.2e-249 ycxD K GntR family transcriptional regulator
LKAIADJA_03572 1.2e-112 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
LKAIADJA_03573 1.7e-114 yczE S membrane
LKAIADJA_03574 4.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
LKAIADJA_03575 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
LKAIADJA_03576 1.3e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
LKAIADJA_03577 1.9e-161 bsdA K LysR substrate binding domain
LKAIADJA_03578 5.4e-107 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
LKAIADJA_03579 1.2e-282 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
LKAIADJA_03580 8.9e-39 bsdD 4.1.1.61 S response to toxic substance
LKAIADJA_03581 3.9e-38 yclD
LKAIADJA_03582 7.1e-158 yclE 3.4.11.5 S Alpha beta hydrolase
LKAIADJA_03583 1.2e-261 dtpT E amino acid peptide transporter
LKAIADJA_03584 2e-292 yclG M Pectate lyase superfamily protein
LKAIADJA_03586 7.8e-278 gerKA EG Spore germination protein
LKAIADJA_03587 8e-227 gerKC S spore germination
LKAIADJA_03588 1.3e-194 gerKB F Spore germination protein
LKAIADJA_03589 7.3e-121 yclH P ABC transporter
LKAIADJA_03590 4e-201 yclI V ABC transporter (permease) YclI
LKAIADJA_03591 2.1e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKAIADJA_03592 8.3e-260 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
LKAIADJA_03593 1.2e-70 S aspartate phosphatase
LKAIADJA_03596 4.1e-232 lysC 2.7.2.4 E Belongs to the aspartokinase family
LKAIADJA_03598 4.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKAIADJA_03599 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKAIADJA_03600 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
LKAIADJA_03601 9.4e-167 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
LKAIADJA_03602 4.1e-251 ycnB EGP Major facilitator Superfamily
LKAIADJA_03603 5.5e-153 ycnC K Transcriptional regulator
LKAIADJA_03604 2.2e-134 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
LKAIADJA_03605 1.6e-45 ycnE S Monooxygenase
LKAIADJA_03606 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
LKAIADJA_03607 4e-270 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LKAIADJA_03608 1.4e-245 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LKAIADJA_03609 1.1e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LKAIADJA_03610 6.1e-149 glcU U Glucose uptake
LKAIADJA_03611 1.4e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKAIADJA_03612 6.6e-97 ycnI S protein conserved in bacteria
LKAIADJA_03613 1.1e-305 ycnJ P protein, homolog of Cu resistance protein CopC
LKAIADJA_03614 1.6e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
LKAIADJA_03615 7.3e-56
LKAIADJA_03616 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
LKAIADJA_03617 5.7e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
LKAIADJA_03618 3.4e-208 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
LKAIADJA_03619 1.1e-200 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
LKAIADJA_03620 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
LKAIADJA_03621 1.2e-73 sipT 3.4.21.89 U Belongs to the peptidase S26 family
LKAIADJA_03622 8.8e-110 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
LKAIADJA_03623 3.5e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
LKAIADJA_03624 2.6e-208 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LKAIADJA_03625 6.8e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
LKAIADJA_03626 2.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
LKAIADJA_03627 4.4e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LKAIADJA_03628 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LKAIADJA_03629 4.5e-88 yaiI S Belongs to the UPF0178 family
LKAIADJA_03630 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
LKAIADJA_03631 4.5e-112 ccpN K CBS domain
LKAIADJA_03632 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
LKAIADJA_03633 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
LKAIADJA_03634 9e-144 recO L Involved in DNA repair and RecF pathway recombination
LKAIADJA_03635 8.4e-19 S YqzL-like protein
LKAIADJA_03636 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LKAIADJA_03637 3.5e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
LKAIADJA_03638 2.5e-59 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
LKAIADJA_03639 8.8e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LKAIADJA_03640 0.0 yqfF S membrane-associated HD superfamily hydrolase
LKAIADJA_03642 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
LKAIADJA_03643 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
LKAIADJA_03644 2.7e-45 yqfC S sporulation protein YqfC
LKAIADJA_03645 4.3e-23 yqfB
LKAIADJA_03646 4.3e-122 yqfA S UPF0365 protein
LKAIADJA_03647 2.3e-227 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
LKAIADJA_03648 2.5e-61 yqeY S Yqey-like protein
LKAIADJA_03649 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
LKAIADJA_03650 1.5e-156 yqeW P COG1283 Na phosphate symporter
LKAIADJA_03651 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
LKAIADJA_03652 3.6e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LKAIADJA_03653 5.4e-175 prmA J Methylates ribosomal protein L11
LKAIADJA_03654 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LKAIADJA_03655 0.0 dnaK O Heat shock 70 kDa protein
LKAIADJA_03656 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LKAIADJA_03657 6.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LKAIADJA_03658 1.7e-215 hemN H Involved in the biosynthesis of porphyrin-containing compound
LKAIADJA_03659 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LKAIADJA_03660 7.2e-53 yqxA S Protein of unknown function (DUF3679)
LKAIADJA_03661 1.5e-222 spoIIP M stage II sporulation protein P
LKAIADJA_03662 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LKAIADJA_03663 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
LKAIADJA_03664 6.2e-188 holA 2.7.7.7 L DNA polymerase III delta subunit
LKAIADJA_03665 0.0 comEC S Competence protein ComEC
LKAIADJA_03666 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
LKAIADJA_03667 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
LKAIADJA_03668 2.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LKAIADJA_03669 3.2e-138 yqeM Q Methyltransferase
LKAIADJA_03670 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LKAIADJA_03671 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
LKAIADJA_03672 3.8e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LKAIADJA_03673 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
LKAIADJA_03674 5.1e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LKAIADJA_03675 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
LKAIADJA_03676 5.3e-95 yqeG S hydrolase of the HAD superfamily
LKAIADJA_03678 1.4e-141 yqeF E GDSL-like Lipase/Acylhydrolase
LKAIADJA_03679 5.2e-96 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LKAIADJA_03680 8.8e-105 yqeD S SNARE associated Golgi protein
LKAIADJA_03681 5e-170 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
LKAIADJA_03682 6.3e-131 yqeB
LKAIADJA_03683 1.6e-35 nucB M Deoxyribonuclease NucA/NucB
LKAIADJA_03684 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LKAIADJA_03685 3.4e-31 csfB S Inhibitor of sigma-G Gin
LKAIADJA_03686 2e-101 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
LKAIADJA_03687 2.2e-202 yaaN P Belongs to the TelA family
LKAIADJA_03688 1.8e-270 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
LKAIADJA_03689 3.1e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LKAIADJA_03690 2.2e-54 yaaQ S protein conserved in bacteria
LKAIADJA_03691 1e-70 yaaR S protein conserved in bacteria
LKAIADJA_03692 2.2e-182 holB 2.7.7.7 L DNA polymerase III
LKAIADJA_03693 6.1e-146 yaaT S stage 0 sporulation protein
LKAIADJA_03694 4.8e-31 yabA L Involved in initiation control of chromosome replication
LKAIADJA_03695 1.2e-137 yabB 2.1.1.223 S Conserved hypothetical protein 95
LKAIADJA_03696 1.5e-49 yazA L endonuclease containing a URI domain
LKAIADJA_03697 4.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LKAIADJA_03698 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
LKAIADJA_03699 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LKAIADJA_03700 7.6e-143 tatD L hydrolase, TatD
LKAIADJA_03701 5.8e-167 rpfB GH23 T protein conserved in bacteria
LKAIADJA_03702 7.9e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LKAIADJA_03703 4.2e-153 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LKAIADJA_03704 3.7e-133 yabG S peptidase
LKAIADJA_03705 7.8e-39 veg S protein conserved in bacteria
LKAIADJA_03706 8.3e-27 sspF S DNA topological change
LKAIADJA_03707 2.7e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LKAIADJA_03708 5.9e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
LKAIADJA_03709 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
LKAIADJA_03710 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
LKAIADJA_03711 1.2e-228 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LKAIADJA_03712 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LKAIADJA_03713 1.5e-96 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LKAIADJA_03714 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LKAIADJA_03715 2.4e-39 yabK S Peptide ABC transporter permease
LKAIADJA_03716 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LKAIADJA_03717 1.5e-92 spoVT K stage V sporulation protein
LKAIADJA_03718 7.8e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LKAIADJA_03719 3e-244 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
LKAIADJA_03720 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
LKAIADJA_03721 1.5e-49 yabP S Sporulation protein YabP
LKAIADJA_03722 2.5e-107 yabQ S spore cortex biosynthesis protein
LKAIADJA_03723 1.1e-44 divIC D Septum formation initiator
LKAIADJA_03724 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
LKAIADJA_03727 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
LKAIADJA_03728 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
LKAIADJA_03729 2.9e-182 KLT serine threonine protein kinase
LKAIADJA_03730 8.5e-273 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LKAIADJA_03731 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
LKAIADJA_03732 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LKAIADJA_03733 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LKAIADJA_03734 8.4e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LKAIADJA_03735 1e-151 yacD 5.2.1.8 O peptidyl-prolyl isomerase
LKAIADJA_03736 2.8e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
LKAIADJA_03737 2.2e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LKAIADJA_03738 4.3e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
LKAIADJA_03739 3.7e-165 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
LKAIADJA_03740 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LKAIADJA_03741 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LKAIADJA_03742 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LKAIADJA_03743 4.1e-30 yazB K transcriptional
LKAIADJA_03744 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LKAIADJA_03745 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
LKAIADJA_03746 1.7e-29 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LKAIADJA_03747 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
LKAIADJA_03748 5.7e-50 yviE
LKAIADJA_03749 3e-154 flgL N Belongs to the bacterial flagellin family
LKAIADJA_03750 1.2e-264 flgK N flagellar hook-associated protein
LKAIADJA_03751 9.2e-78 flgN NOU FlgN protein
LKAIADJA_03752 1e-38 flgM KNU Negative regulator of flagellin synthesis
LKAIADJA_03753 2e-73 yvyF S flagellar protein
LKAIADJA_03754 1.2e-126 comFC S Phosphoribosyl transferase domain
LKAIADJA_03755 8.3e-45 comFB S Late competence development protein ComFB
LKAIADJA_03756 6.9e-267 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LKAIADJA_03757 4.8e-154 degV S protein conserved in bacteria
LKAIADJA_03758 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LKAIADJA_03759 1.5e-182 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
LKAIADJA_03760 5.9e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
LKAIADJA_03761 6e-163 yvhJ K Transcriptional regulator
LKAIADJA_03762 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
LKAIADJA_03763 1.3e-234 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
LKAIADJA_03764 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
LKAIADJA_03765 3.9e-114 tuaF M protein involved in exopolysaccharide biosynthesis
LKAIADJA_03766 2.7e-261 tuaE M Teichuronic acid biosynthesis protein
LKAIADJA_03767 4.9e-257 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LKAIADJA_03768 1.2e-219 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
LKAIADJA_03769 4.4e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LKAIADJA_03770 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
LKAIADJA_03771 5.6e-267 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LKAIADJA_03772 0.0 lytB 3.5.1.28 D Stage II sporulation protein
LKAIADJA_03773 6e-38
LKAIADJA_03774 4e-162 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
LKAIADJA_03775 1e-215 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LKAIADJA_03776 7.6e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
LKAIADJA_03777 2.2e-277 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
LKAIADJA_03778 1.1e-150 tagG GM Transport permease protein
LKAIADJA_03779 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LKAIADJA_03780 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
LKAIADJA_03781 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
LKAIADJA_03782 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
LKAIADJA_03783 1.5e-214 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LKAIADJA_03784 1.2e-260
LKAIADJA_03785 5.2e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LKAIADJA_03786 6.7e-189 pmi 5.3.1.8 G mannose-6-phosphate isomerase
LKAIADJA_03787 5.4e-196 gerBA EG Spore germination protein
LKAIADJA_03788 3.6e-141 gerBB E Spore germination protein
LKAIADJA_03789 1.4e-211 gerAC S Spore germination protein
LKAIADJA_03790 3.9e-246 ywtG EGP Major facilitator Superfamily
LKAIADJA_03791 2.4e-170 ywtF K Transcriptional regulator
LKAIADJA_03792 1e-159 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
LKAIADJA_03793 9.8e-161 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
LKAIADJA_03794 5.1e-292 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKAIADJA_03795 8e-232 dltB M membrane protein involved in D-alanine export
LKAIADJA_03796 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKAIADJA_03797 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LKAIADJA_03798 6.2e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
LKAIADJA_03799 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
LKAIADJA_03800 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LKAIADJA_03801 5.6e-37 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
LKAIADJA_03802 4.5e-247 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LKAIADJA_03803 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
LKAIADJA_03804 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
LKAIADJA_03805 1.1e-19 yxzF
LKAIADJA_03806 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
LKAIADJA_03807 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
LKAIADJA_03808 2.6e-44 yxlH EGP Major facilitator Superfamily
LKAIADJA_03809 2.9e-157 yxlH EGP Major facilitator Superfamily
LKAIADJA_03810 1.2e-138 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LKAIADJA_03811 2.1e-146 yxlF V ABC transporter, ATP-binding protein
LKAIADJA_03812 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
LKAIADJA_03813 4.9e-28
LKAIADJA_03814 2.5e-39 yxlC S Family of unknown function (DUF5345)
LKAIADJA_03815 4e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
LKAIADJA_03816 1.5e-253 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
LKAIADJA_03817 1.9e-155 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LKAIADJA_03818 0.0 cydD V ATP-binding protein
LKAIADJA_03819 1.7e-310 cydD V ATP-binding
LKAIADJA_03820 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
LKAIADJA_03821 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
LKAIADJA_03822 1.5e-229 cimH C COG3493 Na citrate symporter
LKAIADJA_03823 1e-309 3.4.24.84 O Peptidase family M48
LKAIADJA_03825 8.9e-153 yxkH G Polysaccharide deacetylase
LKAIADJA_03826 5.9e-205 msmK P Belongs to the ABC transporter superfamily
LKAIADJA_03827 4.5e-163 lrp QT PucR C-terminal helix-turn-helix domain
LKAIADJA_03828 6.3e-271 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LKAIADJA_03829 4.7e-146 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LKAIADJA_03830 2.4e-73 yxkC S Domain of unknown function (DUF4352)
LKAIADJA_03831 1e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LKAIADJA_03832 3.4e-77 S Protein of unknown function (DUF1453)
LKAIADJA_03833 8.9e-186 yxjM T Signal transduction histidine kinase
LKAIADJA_03834 1.9e-113 K helix_turn_helix, Lux Regulon
LKAIADJA_03835 6.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
LKAIADJA_03836 1.6e-85 yxjI S LURP-one-related
LKAIADJA_03837 3.9e-220 yxjG 2.1.1.14 E Methionine synthase
LKAIADJA_03838 8.2e-218 yxjG 2.1.1.14 E Methionine synthase
LKAIADJA_03839 1.8e-90 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
LKAIADJA_03840 2.1e-26 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
LKAIADJA_03841 2.6e-112 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
LKAIADJA_03842 9e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LKAIADJA_03843 1.6e-250 yxjC EG COG2610 H gluconate symporter and related permeases
LKAIADJA_03844 7.1e-158 rlmA 2.1.1.187 Q Methyltransferase domain
LKAIADJA_03845 2.7e-154 ytnP S Metallo-beta-lactamase superfamily protein
LKAIADJA_03846 7.5e-52 ytzB S Small secreted protein
LKAIADJA_03847 1.1e-198 pepA 3.4.11.7 G aminopeptidase
LKAIADJA_03848 2.1e-51 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
LKAIADJA_03849 2.4e-153 ytpQ S Belongs to the UPF0354 family
LKAIADJA_03850 1.5e-98 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LKAIADJA_03851 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
LKAIADJA_03852 9.7e-247 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
LKAIADJA_03853 8.1e-21 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LKAIADJA_03854 1.8e-122 5.4.99.22 M Membrane
LKAIADJA_03855 2.5e-200 aroF 2.5.1.54, 5.4.99.5 E chorismate mutase
LKAIADJA_03856 9.4e-178 ccpA K Catabolite control protein A
LKAIADJA_03857 1.9e-230 acuC BQ COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein
LKAIADJA_03858 3.5e-117 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
LKAIADJA_03859 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LKAIADJA_03860 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
LKAIADJA_03861 4.1e-159 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LKAIADJA_03862 5.3e-242 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LKAIADJA_03863 3.1e-221 htrA 3.4.21.107 O serine protease
LKAIADJA_03864 1.6e-106 plsC 2.3.1.51 I 1-acyl-sn-glycerol-3-phosphate acyltransferase
LKAIADJA_03865 6.3e-242 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G PTS system
LKAIADJA_03866 1.1e-203 2.6.1.9 S HAD-hyrolase-like
LKAIADJA_03867 1.3e-298 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LKAIADJA_03868 6.9e-212 dhsS 1.12.1.2 E Aminotransferase
LKAIADJA_03869 8.2e-73 osmC O redox protein, regulator of disulfide bond formation
LKAIADJA_03870 1e-123 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LKAIADJA_03871 6.5e-90 speG 2.3.1.57 J Acetyltransferase (GNAT) domain
LKAIADJA_03872 2.2e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LKAIADJA_03873 3.5e-74 ytsP 1.8.4.14 T COG1956 GAF domain-containing protein
LKAIADJA_03874 8.4e-251 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LKAIADJA_03875 7e-193 iscS2 2.8.1.7 E COG1104 Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
LKAIADJA_03876 4.1e-223 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LKAIADJA_03877 1.5e-125 yfcA S membrane transporter protein
LKAIADJA_03878 4.4e-167 sppA OU Peptidase family S49
LKAIADJA_03879 1e-88 yteJ S RDD family
LKAIADJA_03880 2.1e-85 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LKAIADJA_03881 3.2e-159 ytxK 2.1.1.72 L N-6 DNA Methylase
LKAIADJA_03882 3e-226 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LKAIADJA_03883 2.5e-177 S Esterase-like activity of phytase
LKAIADJA_03884 3.3e-86 uspA T Universal stress protein
LKAIADJA_03885 6.8e-201 ald 1.4.1.1 E Belongs to the AlaDH PNT family
LKAIADJA_03886 1.2e-109 cutC P Participates in the control of copper homeostasis
LKAIADJA_03887 3e-190 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
LKAIADJA_03888 1e-130 ytkL S Belongs to the UPF0173 family
LKAIADJA_03889 3.2e-63 T Universal stress protein family
LKAIADJA_03890 3e-232 ytoI K DRTGG domain
LKAIADJA_03891 1.7e-173 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain
LKAIADJA_03892 0.0 dnaE 2.7.7.7 L DNA polymerase
LKAIADJA_03893 3.6e-227 ytsJ 1.1.1.38 C Malic enzyme
LKAIADJA_03894 2.7e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LKAIADJA_03895 6.5e-168 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
LKAIADJA_03896 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LKAIADJA_03897 0.0 pyk 2.7.1.40, 2.7.7.4 F Belongs to the pyruvate kinase family
LKAIADJA_03898 7.7e-247 cycA E permease
LKAIADJA_03899 9.3e-198 citZ 2.3.3.1 C Belongs to the citrate synthase family
LKAIADJA_03900 3.1e-242 icd 1.1.1.42 C Isocitrate dehydrogenase NADP
LKAIADJA_03901 1.2e-126 T Alkaline phosphatase synthesis transcriptional regulatory protein
LKAIADJA_03902 2.5e-287 phoR 2.7.13.3 T Histidine kinase
LKAIADJA_03903 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LKAIADJA_03904 1.1e-161 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LKAIADJA_03905 2.1e-106 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LKAIADJA_03906 6.1e-188 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LKAIADJA_03907 9.3e-83 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LKAIADJA_03908 8.2e-236 dnaB L membrane attachment protein
LKAIADJA_03909 1.8e-170 dnaI L Primosomal protein DnaI
LKAIADJA_03910 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LKAIADJA_03911 4.9e-271 lysP E permease
LKAIADJA_03912 5.4e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LKAIADJA_03913 2.2e-25 rpmI J Belongs to the bacterial ribosomal protein bL35 family
LKAIADJA_03914 1.9e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LKAIADJA_03915 7.5e-109 ymaB S DNA mismatch repair protein MutT
LKAIADJA_03916 5.4e-151
LKAIADJA_03917 4.4e-223 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LKAIADJA_03918 5e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LKAIADJA_03919 1.1e-101 engB D Necessary for normal cell division and for the maintenance of normal septation
LKAIADJA_03920 2.3e-235 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LKAIADJA_03921 4.2e-114 hemX O COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component
LKAIADJA_03922 4.9e-168 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
LKAIADJA_03923 2.2e-117 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
LKAIADJA_03924 8.1e-182 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
LKAIADJA_03925 5.2e-245 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
LKAIADJA_03926 1.8e-166 abrB S Transition state regulatory protein AbrB
LKAIADJA_03927 6e-100 tag 3.2.2.20 L glycosylase
LKAIADJA_03928 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LKAIADJA_03929 2.2e-232 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
LKAIADJA_03930 1.6e-46 pilD 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
LKAIADJA_03931 6.5e-151 dkgB S Aldo/keto reductase family
LKAIADJA_03932 7.4e-144 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I Squalene/phytoene synthase
LKAIADJA_03934 1.9e-113 radC E Belongs to the UPF0758 family
LKAIADJA_03935 1.1e-15
LKAIADJA_03936 2.2e-76 S Domain of unknown function (DUF4930)
LKAIADJA_03937 9.6e-16
LKAIADJA_03938 8.2e-122 mreC M Involved in formation and maintenance of cell shape
LKAIADJA_03939 9e-63 mreD M rod shape-determining protein MreD
LKAIADJA_03940 1.3e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
LKAIADJA_03941 6e-49 ysxB J Cysteine protease Prp
LKAIADJA_03942 7.9e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
LKAIADJA_03943 1.6e-238 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LKAIADJA_03944 5e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
LKAIADJA_03945 1.2e-98 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LKAIADJA_03946 3.5e-180 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LKAIADJA_03947 1.4e-184 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LKAIADJA_03948 6.7e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LKAIADJA_03949 2.3e-38 yajC U Preprotein translocase subunit YajC
LKAIADJA_03950 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LKAIADJA_03951 0.0 recJ L single-stranded-DNA-specific exonuclease recJ
LKAIADJA_03952 2.3e-90 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LKAIADJA_03953 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LKAIADJA_03954 1.1e-72 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LKAIADJA_03955 2.9e-154 lytH 3.5.1.28 M Probably involved in cell-wall metabolism
LKAIADJA_03956 4.1e-226 hisS 6.1.1.21 J histidyl-tRNA synthetase
LKAIADJA_03957 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
LKAIADJA_03958 1.6e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
LKAIADJA_03959 6e-233 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
LKAIADJA_03960 8.6e-72 cymR K Transcriptional regulator
LKAIADJA_03961 1.5e-09 csbD S Belongs to the UPF0337 (CsbD) family
LKAIADJA_03962 1.1e-09
LKAIADJA_03963 1e-179 luxA C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LKAIADJA_03964 7.3e-276 ma_1747 S ABC transporter
LKAIADJA_03965 5.9e-208 iscS 2.8.1.7 E Cysteine desulfurase
LKAIADJA_03966 1.9e-214 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LKAIADJA_03967 3.8e-114 S Tetratricopeptide repeat
LKAIADJA_03968 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LKAIADJA_03969 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LKAIADJA_03970 1.3e-41 yrzL S Belongs to the UPF0297 family
LKAIADJA_03971 3.3e-71 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LKAIADJA_03972 3.1e-53 yrzB S Belongs to the UPF0473 family
LKAIADJA_03973 1.9e-107 yrrM 2.1.1.104 S O-methyltransferase
LKAIADJA_03974 3.7e-168 yegQ O Peptidase U32
LKAIADJA_03975 2.7e-238 yegQ O Peptidase U32 family
LKAIADJA_03976 8.2e-111 udk 2.7.1.48 F Cytidine monophosphokinase
LKAIADJA_03977 1.3e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LKAIADJA_03978 3.8e-123 ybgJ 3.5.1.54 E allophanate hydrolase subunit 1
LKAIADJA_03979 1.8e-163 kipA 3.5.1.54, 6.3.4.6 E allophanate hydrolase subunit 2
LKAIADJA_03980 5.1e-59 accB 2.3.1.12, 4.1.1.3 I biotin carboxyl carrier protein
LKAIADJA_03981 2.8e-241 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase (Biotin carboxylase subunit)
LKAIADJA_03982 1.8e-136 lamB S Belongs to the UPF0271 (lamB) family
LKAIADJA_03983 1e-197 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
LKAIADJA_03984 2.4e-116 mtnN 3.2.2.16, 3.2.2.9 F Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LKAIADJA_03985 7.7e-86 yqeG S Mitochondrial PGP phosphatase
LKAIADJA_03986 2.9e-204 yqeH S GTPase YqeH
LKAIADJA_03987 1.3e-140 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LKAIADJA_03988 8.1e-45 yhbY J RNA-binding protein
LKAIADJA_03989 3.4e-95 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LKAIADJA_03990 8e-100 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
LKAIADJA_03991 4.1e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LKAIADJA_03992 5.7e-124 yqeM Q Methyltransferase
LKAIADJA_03993 1.1e-39 comEA L DNA uptake protein and related DNA-binding
LKAIADJA_03994 8.2e-84 comEB 3.5.4.12 F ComE operon protein 2
LKAIADJA_03996 3.1e-171 comEC S Competence protein ComEC
LKAIADJA_03997 7.6e-172 holA 2.7.7.7 L DNA polymerase III delta' subunit
LKAIADJA_03998 2.1e-33 rpsT J Binds directly to 16S ribosomal RNA
LKAIADJA_03999 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LKAIADJA_04000 7.7e-184 hemN H Involved in the biosynthesis of porphyrin-containing compound
LKAIADJA_04001 5.3e-173 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LKAIADJA_04002 1.6e-77 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LKAIADJA_04003 0.0 dnaK O Heat shock 70 kDa protein
LKAIADJA_04004 2.2e-191 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LKAIADJA_04005 8.4e-168 prmA J Ribosomal protein L11 methyltransferase
LKAIADJA_04006 2e-127 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LKAIADJA_04007 1.4e-235 yqeV 2.8.4.5 J Uncharacterized protein family UPF0004
LKAIADJA_04008 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
LKAIADJA_04009 5.5e-95 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
LKAIADJA_04010 1.9e-130 yqfA S UPF0365 protein
LKAIADJA_04011 3.1e-68
LKAIADJA_04012 3.9e-173 phoH T Phosphate starvation-inducible protein PhoH
LKAIADJA_04013 1.3e-76 ybeY 2.6.99.2, 3.5.4.5 J Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LKAIADJA_04014 2.8e-41 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
LKAIADJA_04015 5e-69 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
LKAIADJA_04016 6.8e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LKAIADJA_04017 2.8e-129 recO L Involved in DNA repair and RecF pathway recombination
LKAIADJA_04018 3e-278 glyQS 6.1.1.14 J Belongs to the class-II aminoacyl-tRNA synthetase family
LKAIADJA_04019 3.1e-87 ccpN K CBS domain
LKAIADJA_04020 1.1e-147 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
LKAIADJA_04021 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LKAIADJA_04022 8.3e-199 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LKAIADJA_04023 1.2e-99 trmK 2.1.1.217 S tRNA (adenine(22)-N(1))-methyltransferase
LKAIADJA_04024 6.8e-185 ybgI 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LKAIADJA_04025 1.6e-220 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LKAIADJA_04026 2.6e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LKAIADJA_04027 4.4e-138 zurA P ABC transporter, ATP-binding protein
LKAIADJA_04028 4.4e-131 znuB P ABC transporter
LKAIADJA_04029 5e-72 zur P Belongs to the Fur family
LKAIADJA_04030 2e-114 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
LKAIADJA_04031 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
LKAIADJA_04032 1.6e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
LKAIADJA_04033 8.2e-83 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LKAIADJA_04034 9.1e-254 gluP 3.4.21.105 S Rhomboid family
LKAIADJA_04035 4.5e-26 yqgQ S Bacterial protein of unknown function (DUF910)
LKAIADJA_04036 7.9e-185 glk 2.7.1.2 G glucokinase
LKAIADJA_04037 1.4e-50 yqgV S Thiamine-binding protein
LKAIADJA_04038 9.1e-110 ycbL 3.1.2.6 S metallo-beta-lactamase superfamily protein
LKAIADJA_04039 9.6e-167 comGA NU competence protein comGA
LKAIADJA_04040 6.1e-106 comGB NU Late competence protein ComGB, access of DNA to ComEA
LKAIADJA_04041 8.6e-40 comGC U Required for transformation and DNA binding
LKAIADJA_04042 3.1e-55 NU COG2165 Type II secretory pathway, pseudopilin PulG
LKAIADJA_04043 3.4e-11
LKAIADJA_04044 4.9e-41 comGF U Competence protein ComGF
LKAIADJA_04046 2.3e-82 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LKAIADJA_04047 1.5e-197 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
LKAIADJA_04048 4.5e-239 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LKAIADJA_04049 8.5e-284 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LKAIADJA_04050 6.5e-66 yqhL P Rhodanese Homology Domain
LKAIADJA_04051 5.7e-152 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
LKAIADJA_04052 1e-20
LKAIADJA_04053 2.5e-21
LKAIADJA_04054 1.2e-178 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
LKAIADJA_04055 3.2e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LKAIADJA_04056 5.1e-73 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LKAIADJA_04057 5.3e-256 accC 6.3.4.14, 6.4.1.2 I Biotin carboxylase
LKAIADJA_04058 1.3e-55 yqhY S protein conserved in bacteria
LKAIADJA_04059 1.6e-64 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LKAIADJA_04060 2.6e-207 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LKAIADJA_04061 8.7e-32 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LKAIADJA_04062 9.7e-150 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LKAIADJA_04063 1e-78 argR K Regulates arginine biosynthesis genes
LKAIADJA_04064 9.1e-266 recN L May be involved in recombinational repair of damaged DNA
LKAIADJA_04065 1.9e-148 pta 2.3.1.19, 2.3.1.8 C Phosphate acetyl/butaryl transferase
LKAIADJA_04066 9.3e-227 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LKAIADJA_04067 4.9e-174 bfmBAA 1.2.4.4 C Dehydrogenase E1 component
LKAIADJA_04068 5.5e-178 bfmBAB 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LKAIADJA_04069 8.4e-219 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LKAIADJA_04070 3e-75 yqiW S Belongs to the UPF0403 family
LKAIADJA_04071 1.9e-162 yqjA S Putative aromatic acid exporter C-terminal domain
LKAIADJA_04072 6.6e-191 yqjE 3.4.11.4 E Peptidase T-like protein
LKAIADJA_04073 1e-265 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LKAIADJA_04074 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha-amylase domain
LKAIADJA_04075 6.6e-159 K Transcriptional regulator
LKAIADJA_04076 4.9e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LKAIADJA_04077 1.1e-172 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LKAIADJA_04078 1.3e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LKAIADJA_04079 6.4e-126 S KR domain
LKAIADJA_04080 4.1e-167 yqkF C aldo keto reductase
LKAIADJA_04081 1.6e-91 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
LKAIADJA_04082 5e-78 fur P Belongs to the Fur family
LKAIADJA_04083 1.5e-163 xerD D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids
LKAIADJA_04084 9.7e-78 ypuF S Domain of unknown function (DUF309)
LKAIADJA_04085 3.8e-123 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LKAIADJA_04086 2.7e-89 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LKAIADJA_04087 4.6e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LKAIADJA_04088 2e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKAIADJA_04089 0.0 resE 2.7.13.3 T Histidine kinase
LKAIADJA_04090 8.3e-83 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LKAIADJA_04091 1.4e-40 fer C Ferredoxin
LKAIADJA_04092 9.6e-151 ypbB 5.1.3.1 S Helix-turn-helix domain
LKAIADJA_04093 2.7e-255 recQ1 3.6.4.12 L DNA helicase
LKAIADJA_04094 7.7e-20 3.5.1.28 CBM50 M Lysin motif
LKAIADJA_04095 3.8e-187 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 C Thioredoxin reductase
LKAIADJA_04096 3.1e-173 ansA 3.5.1.1 EJ L-asparaginase
LKAIADJA_04097 5.8e-107 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
LKAIADJA_04098 5e-210 rpsA 1.17.7.4 J Ribosomal protein S1
LKAIADJA_04099 5.3e-245 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
LKAIADJA_04100 5.4e-173 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
LKAIADJA_04101 8.7e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LKAIADJA_04102 9e-93
LKAIADJA_04103 4e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
LKAIADJA_04104 3.2e-170 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LKAIADJA_04105 5e-78 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
LKAIADJA_04106 2.1e-216 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LKAIADJA_04107 8.3e-180 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LKAIADJA_04108 7.4e-231 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
LKAIADJA_04109 1.7e-229 G COG0457 FOG TPR repeat
LKAIADJA_04110 5.5e-90 ypiB S UPF0302 domain
LKAIADJA_04111 4e-86 ypjA S Protein of unknown function (DUF1405)
LKAIADJA_04112 1.1e-100 yugP S Putative neutral zinc metallopeptidase
LKAIADJA_04113 5.7e-52 ypjD 2.5.1.19 S MazG nucleotide pyrophosphohydrolase
LKAIADJA_04114 4.9e-202 bshA GT4 M Glycosyl transferase 4-like
LKAIADJA_04115 3.4e-206 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LKAIADJA_04116 5.3e-173 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LKAIADJA_04117 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
LKAIADJA_04118 3.5e-249 asnS 6.1.1.22 J asparaginyl-tRNA
LKAIADJA_04119 9.3e-116 dnaD L replication protein DnaD
LKAIADJA_04120 4.9e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LKAIADJA_04121 2.3e-46
LKAIADJA_04122 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding protein
LKAIADJA_04123 1e-116 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LKAIADJA_04124 7.5e-50 yppE S Bacterial domain of unknown function (DUF1798)
LKAIADJA_04125 4e-104 ypsA S Belongs to the UPF0398 family
LKAIADJA_04126 8.5e-49 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LKAIADJA_04127 1.2e-208 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
LKAIADJA_04128 6.4e-157 rarD S RarD protein
LKAIADJA_04129 3.6e-106 GM NAD(P)H-binding
LKAIADJA_04130 0.0 ypbR S Dynamin family
LKAIADJA_04131 2e-163 polA 2.7.7.7 L 5'-3' exonuclease
LKAIADJA_04132 6.9e-66 rnhA 3.1.26.4 L Cell wall enzyme EbsB
LKAIADJA_04133 9.6e-87 S Serine hydrolase
LKAIADJA_04134 2.9e-112 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LKAIADJA_04135 5.5e-37 ypgR C Scaffold protein Nfu/NifU N terminal
LKAIADJA_04136 6.7e-156 ypgR C virulence factor
LKAIADJA_04137 5.3e-72 S Belongs to the UPF0403 family
LKAIADJA_04138 2.3e-181 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LKAIADJA_04139 4.6e-85 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LKAIADJA_04140 3.6e-146 degV S DegV family
LKAIADJA_04141 9.7e-97 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LKAIADJA_04142 3.1e-77 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
LKAIADJA_04143 4.8e-85 crr 2.7.1.193, 2.7.1.199 G PTS system
LKAIADJA_04144 2.2e-34 yozE S Belongs to the UPF0346 family
LKAIADJA_04145 2.3e-252 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
LKAIADJA_04146 6.1e-88 K Acetyltransferase
LKAIADJA_04147 1.1e-195 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LKAIADJA_04148 8.6e-105 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I acid phosphatase family protein
LKAIADJA_04149 4.3e-118 K response regulator ArlR
LKAIADJA_04150 1.8e-240 arlS 2.7.13.3 T Member of the two-component regulatory system ArlS ArlR. ArlS probably functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to ArlR (By similarity)
LKAIADJA_04151 0.0 odhA 1.2.4.2 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
LKAIADJA_04152 2.4e-165 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
LKAIADJA_04154 2.1e-86 ydcN K Cupin domain
LKAIADJA_04155 2.7e-79 E LysE type translocator
LKAIADJA_04156 2.1e-157 K to gi 15894612 ref NP_347961.1 Clostridium acetobutylicum ATCC 824 , percent identity
LKAIADJA_04157 8.4e-138 G Xylose isomerase-like TIM barrel
LKAIADJA_04158 2.3e-154 G Xylose isomerase-like TIM barrel
LKAIADJA_04159 2.9e-186 S Oxidoreductase family, C-terminal alpha/beta domain
LKAIADJA_04160 4e-176 S Oxidoreductase family, C-terminal alpha/beta domain
LKAIADJA_04161 6.7e-96 yyaP 1.5.1.3 H RibD C-terminal domain
LKAIADJA_04162 1.5e-21
LKAIADJA_04163 1.3e-145 E Lactoylglutathione lyase
LKAIADJA_04164 5.5e-32 yozC
LKAIADJA_04165 1.3e-137 yojN S ATPase activity
LKAIADJA_04166 0.0 H Nitric oxide reductase activation protein
LKAIADJA_04167 3.3e-234 brnQ E Component of the transport system for branched-chain amino acids
LKAIADJA_04168 1.2e-176 yaaN P Belongs to the TelA family
LKAIADJA_04169 3.1e-102 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
LKAIADJA_04170 1.8e-38 acyP 3.6.1.7 C Belongs to the acylphosphatase family
LKAIADJA_04171 6.3e-56 S Protein of unknown function (DUF1033)
LKAIADJA_04172 3e-30 cspA K Cold shock protein CspA
LKAIADJA_04173 9.1e-234 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LKAIADJA_04174 6.2e-191 alr 5.1.1.1, 6.3.2.10 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LKAIADJA_04175 7.8e-216 dapL 3.5.1.47 E hydrolase activity
LKAIADJA_04176 1.3e-80 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LKAIADJA_04177 3.6e-126 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LKAIADJA_04178 2.3e-159 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LKAIADJA_04179 5.2e-176 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LKAIADJA_04180 4.5e-214 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
LKAIADJA_04181 1.1e-150 dkgB S Aldo/keto reductase family
LKAIADJA_04182 5.8e-302 ybiT S ABC transporter, ATP-binding protein
LKAIADJA_04183 1.1e-167 cvfB S Virulence factor B
LKAIADJA_04184 3.4e-172 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
LKAIADJA_04185 6.2e-155 pstC P probably responsible for the translocation of the substrate across the membrane
LKAIADJA_04186 2.7e-155 pstA P Phosphate transport system permease
LKAIADJA_04187 2.2e-157 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LKAIADJA_04188 3.2e-110 phoU P Plays a role in the regulation of phosphate uptake
LKAIADJA_04189 0.0 pepF E Oligoendopeptidase F
LKAIADJA_04190 2.4e-51 icmF
LKAIADJA_04191 6.6e-123 mta K Transcriptional regulator
LKAIADJA_04192 7e-170 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
LKAIADJA_04193 3.4e-24 cfa 2.1.1.317, 2.1.1.79 M Mycolic acid cyclopropane synthetase
LKAIADJA_04194 2.1e-75 S Short repeat of unknown function (DUF308)
LKAIADJA_04195 4.6e-238 femB 2.3.2.16, 2.3.2.17, 2.3.2.18 V Methicillin resistance
LKAIADJA_04196 6.5e-240 femA 2.3.2.16, 2.3.2.17 V Methicillin resistance
LKAIADJA_04197 1.2e-115 S DJ-1/PfpI family
LKAIADJA_04198 6e-129 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
LKAIADJA_04199 2.4e-223 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
LKAIADJA_04200 1.3e-100 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
LKAIADJA_04201 2.9e-129 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
LKAIADJA_04202 5.9e-175 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LKAIADJA_04203 3.3e-101 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH COG0512 Anthranilate para-aminobenzoate synthases component II
LKAIADJA_04204 1.8e-251 trpE 4.1.3.27 EH anthranilate synthase component I
LKAIADJA_04205 1.6e-199 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
LKAIADJA_04206 4.9e-58 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LKAIADJA_04207 3.2e-145 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LKAIADJA_04208 1.2e-236 umuC 2.7.7.7 L Belongs to the DNA polymerase type-Y family
LKAIADJA_04209 8.7e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
LKAIADJA_04210 9.1e-157 msrR K Peptide methionine sulfoxide reductase regulator MsrR
LKAIADJA_04211 9.3e-81 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LKAIADJA_04212 5e-157 rbsB G Periplasmic binding protein domain
LKAIADJA_04213 3e-157 rbsC G Belongs to the binding-protein-dependent transport system permease family
LKAIADJA_04214 2e-264 rbsA 3.6.3.17 G ABC transporter, ATP-binding protein
LKAIADJA_04215 5.4e-60 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
LKAIADJA_04216 6.2e-169 rbsR K helix_turn _helix lactose operon repressor
LKAIADJA_04217 7.3e-42
LKAIADJA_04218 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LKAIADJA_04219 5e-213 yubA S AI-2E family transporter
LKAIADJA_04220 3.8e-260 agcS E amino acid carrier protein
LKAIADJA_04221 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LKAIADJA_04222 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LKAIADJA_04223 2.3e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LKAIADJA_04224 3.8e-50 S Belongs to the HesB IscA family
LKAIADJA_04225 1.4e-83 yneP S Thioesterase-like superfamily
LKAIADJA_04226 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LKAIADJA_04227 2.2e-304 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
LKAIADJA_04228 1.4e-51 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LKAIADJA_04229 0.0 sbcC L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity (By similarity)
LKAIADJA_04230 1.6e-197 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
LKAIADJA_04231 9.3e-75 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
LKAIADJA_04232 3.3e-23
LKAIADJA_04233 1.6e-25 yneF S UPF0154 protein
LKAIADJA_04234 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LKAIADJA_04235 7.2e-34 ynzC S UPF0291 protein
LKAIADJA_04236 4.4e-09
LKAIADJA_04237 9.1e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LKAIADJA_04238 1.6e-146 S Cysteine-rich secretory protein family
LKAIADJA_04239 3e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LKAIADJA_04241 1.1e-40 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LKAIADJA_04242 9.7e-39
LKAIADJA_04243 1.3e-295 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
LKAIADJA_04244 1.5e-245 lysP E amino acid
LKAIADJA_04245 1.8e-50
LKAIADJA_04246 3.3e-136 yidA S Sucrose-6F-phosphate phosphohydrolase
LKAIADJA_04247 1.4e-164 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LKAIADJA_04248 1.1e-192 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LKAIADJA_04249 3.2e-226 hom 1.1.1.3, 2.7.2.4 E Homoserine dehydrogenase
LKAIADJA_04250 3.7e-249 lysC 2.7.2.4 E Belongs to the aspartokinase family
LKAIADJA_04251 4.1e-104 E lactoylglutathione lyase activity
LKAIADJA_04252 1.1e-64 S DeoR C terminal sensor domain
LKAIADJA_04253 6.2e-133
LKAIADJA_04254 4.3e-22 S Cna protein B-type domain
LKAIADJA_04255 1.3e-221 S Pfam Methyltransferase
LKAIADJA_04256 9.8e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LKAIADJA_04257 2.4e-147 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
LKAIADJA_04258 1.8e-139 yycI S protein conserved in bacteria
LKAIADJA_04259 1.9e-242 yycH S YycH protein
LKAIADJA_04260 0.0 vicK 2.7.13.3 T WalK functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to WalR
LKAIADJA_04261 3.3e-132 K Transcriptional regulatory protein WalR
LKAIADJA_04262 1.6e-242 lmrB EGP Major facilitator Superfamily
LKAIADJA_04263 2.1e-76 K Transcriptional
LKAIADJA_04266 6.5e-229 CG UDP-glucoronosyl and UDP-glucosyl transferase
LKAIADJA_04267 3.2e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LKAIADJA_04268 1.3e-262 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
LKAIADJA_04269 8.8e-75 rplI J Binds to the 23S rRNA
LKAIADJA_04270 0.0 rplI T signaling protein consisting of a modified GGDEF domain and a DHH domain
LKAIADJA_04271 8.5e-149 yybS S Predicted membrane protein (DUF2232)
LKAIADJA_04272 5.6e-191 metX 2.3.1.31 E Belongs to the AB hydrolase superfamily. MetX family
LKAIADJA_04273 3.7e-46 azlD S Branched-chain amino acid transport protein (AzlD)
LKAIADJA_04274 1.8e-119 azlC E Azaleucine resistance
LKAIADJA_04275 4.9e-243 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LKAIADJA_04276 1.1e-273 hutH 4.3.1.3 E Histidine ammonia-lyase
LKAIADJA_04277 4.7e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LKAIADJA_04278 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LKAIADJA_04279 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LKAIADJA_04280 2.7e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LKAIADJA_04281 1.7e-34 yaaA S S4 domain
LKAIADJA_04282 5.9e-208 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LKAIADJA_04283 1.4e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LKAIADJA_04284 9.2e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
LKAIADJA_04285 6.1e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LKAIADJA_04286 4e-251 mnmE J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LKAIADJA_04287 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LKAIADJA_04288 9.5e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
LKAIADJA_04289 3.4e-144 noc K Belongs to the ParB family
LKAIADJA_04290 5e-268 cstA T Carbon starvation protein
LKAIADJA_04291 1.3e-91 immR_1 K Helix-turn-helix XRE-family like proteins
LKAIADJA_04292 3.7e-257 glpT G Glycerol-3-phosphate transporter
LKAIADJA_04293 6.8e-72 T Universal stress protein family
LKAIADJA_04294 3.3e-172 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LKAIADJA_04295 3.8e-178 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LKAIADJA_04296 1.5e-62 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
LKAIADJA_04298 3.3e-135 S HNH endonuclease
LKAIADJA_04308 3.3e-13
LKAIADJA_04313 5.7e-146 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
LKAIADJA_04315 8.7e-90 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
LKAIADJA_04316 1.6e-85 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
LKAIADJA_04321 2.7e-113 DR0488 S protein conserved in bacteria
LKAIADJA_04322 0.0 S Bacterial DNA polymerase III alpha subunit
LKAIADJA_04323 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
LKAIADJA_04324 4.5e-224 L DNA primase activity
LKAIADJA_04325 9.7e-283 3.6.4.12 J DnaB-like helicase C terminal domain
LKAIADJA_04326 5.3e-86
LKAIADJA_04327 7.6e-180 L AAA domain
LKAIADJA_04328 3.6e-155
LKAIADJA_04332 0.0 M Parallel beta-helix repeats
LKAIADJA_04333 5.7e-144 S Pfam:DUF867
LKAIADJA_04336 1e-159
LKAIADJA_04338 1.5e-126 yoqW S Belongs to the SOS response-associated peptidase family
LKAIADJA_04339 3.7e-148 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
LKAIADJA_04341 8.3e-27
LKAIADJA_04342 1.8e-87
LKAIADJA_04345 1.6e-72
LKAIADJA_04349 1.2e-22
LKAIADJA_04358 6.2e-42
LKAIADJA_04362 1.1e-33 K Transcriptional regulator
LKAIADJA_04363 4.6e-177
LKAIADJA_04364 1.1e-261 S DNA-sulfur modification-associated
LKAIADJA_04365 5.4e-195 L Belongs to the 'phage' integrase family
LKAIADJA_04370 3.1e-103
LKAIADJA_04376 1.4e-27 K Cro/C1-type HTH DNA-binding domain
LKAIADJA_04378 1.9e-74
LKAIADJA_04379 1.6e-166 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
LKAIADJA_04381 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
LKAIADJA_04382 3.4e-219 yqxK 3.6.4.12 L DNA helicase
LKAIADJA_04383 1.3e-57 ansR K Transcriptional regulator
LKAIADJA_04384 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
LKAIADJA_04385 1.9e-267 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
LKAIADJA_04386 3.1e-235 mleN C Na H antiporter
LKAIADJA_04387 5.5e-242 mleA 1.1.1.38 C malic enzyme
LKAIADJA_04388 2.2e-31 yqkK
LKAIADJA_04389 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
LKAIADJA_04390 2.4e-80 fur P Belongs to the Fur family
LKAIADJA_04391 1.4e-36 S Protein of unknown function (DUF4227)
LKAIADJA_04392 2.6e-166 xerD L recombinase XerD
LKAIADJA_04393 1.1e-230 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
LKAIADJA_04394 3.8e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LKAIADJA_04395 2.4e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
LKAIADJA_04396 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
LKAIADJA_04397 5.1e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
LKAIADJA_04398 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LKAIADJA_04399 9.6e-112 spoVAA S Stage V sporulation protein AA
LKAIADJA_04400 1e-67 spoVAB S Stage V sporulation protein AB
LKAIADJA_04401 2.3e-78 spoVAC S stage V sporulation protein AC
LKAIADJA_04402 9e-192 spoVAD I Stage V sporulation protein AD
LKAIADJA_04403 2.2e-57 spoVAEB S stage V sporulation protein
LKAIADJA_04404 1.4e-110 spoVAEA S stage V sporulation protein
LKAIADJA_04405 1.7e-271 spoVAF EG Stage V sporulation protein AF
LKAIADJA_04406 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LKAIADJA_04407 1.8e-149 ypuA S Secreted protein
LKAIADJA_04408 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LKAIADJA_04410 4.7e-09 eaeH M Domain of Unknown Function (DUF1259)
LKAIADJA_04412 1.4e-08 S SNARE associated Golgi protein
LKAIADJA_04413 6.6e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
LKAIADJA_04415 8e-94 sipT 3.4.21.89 U Belongs to the peptidase S26 family
LKAIADJA_04416 7.8e-55 ypuD
LKAIADJA_04417 1.6e-202 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LKAIADJA_04418 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
LKAIADJA_04419 1.9e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LKAIADJA_04420 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
LKAIADJA_04421 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LKAIADJA_04422 3.9e-90 ypuF S Domain of unknown function (DUF309)
LKAIADJA_04423 6.4e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LKAIADJA_04424 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LKAIADJA_04425 4e-98 ypuI S Protein of unknown function (DUF3907)
LKAIADJA_04426 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
LKAIADJA_04427 3.5e-103 spmA S Spore maturation protein
LKAIADJA_04428 1.9e-87 spmB S Spore maturation protein
LKAIADJA_04429 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LKAIADJA_04430 3.6e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
LKAIADJA_04431 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
LKAIADJA_04432 5.3e-212 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
LKAIADJA_04433 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKAIADJA_04434 0.0 resE 2.7.13.3 T Histidine kinase
LKAIADJA_04435 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
LKAIADJA_04436 3.1e-198 rsiX
LKAIADJA_04437 4.2e-133 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
LKAIADJA_04438 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LKAIADJA_04439 4.9e-79 yfiV K transcriptional
LKAIADJA_04440 2.7e-280 yfiU EGP Major facilitator Superfamily
LKAIADJA_04441 4.7e-99 yfiT S Belongs to the metal hydrolase YfiT family
LKAIADJA_04442 2.4e-194 yfiS EGP Major facilitator Superfamily
LKAIADJA_04443 5.4e-107 yfiR K Transcriptional regulator
LKAIADJA_04444 3.8e-196 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
LKAIADJA_04445 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
LKAIADJA_04446 8.3e-99 padR K transcriptional
LKAIADJA_04447 1e-207 V COG0842 ABC-type multidrug transport system, permease component
LKAIADJA_04448 2.2e-213 V ABC-2 family transporter protein
LKAIADJA_04449 3.2e-167 V ABC transporter, ATP-binding protein
LKAIADJA_04450 1.8e-111 KT LuxR family transcriptional regulator
LKAIADJA_04451 8.8e-194 yxjM T Histidine kinase
LKAIADJA_04452 1.1e-161 yfiE 1.13.11.2 S glyoxalase
LKAIADJA_04453 6.4e-64 mhqP S DoxX
LKAIADJA_04454 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
LKAIADJA_04455 2.4e-306 yfiB3 V ABC transporter
LKAIADJA_04456 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LKAIADJA_04457 1.6e-140 glvR K Helix-turn-helix domain, rpiR family
LKAIADJA_04458 4.9e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LKAIADJA_04459 7.4e-44 yfjA S Belongs to the WXG100 family
LKAIADJA_04460 6.2e-171 yfjB
LKAIADJA_04461 2.7e-124 yfjC
LKAIADJA_04462 1.1e-85 S Family of unknown function (DUF5381)
LKAIADJA_04463 4e-56 yfjF S UPF0060 membrane protein
LKAIADJA_04464 1.2e-25 sspH S Belongs to the SspH family
LKAIADJA_04465 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
LKAIADJA_04466 1.2e-252 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LKAIADJA_04467 2.8e-192 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LKAIADJA_04468 8.5e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LKAIADJA_04469 2.2e-190 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LKAIADJA_04470 2.3e-29 yfjL
LKAIADJA_04471 1.9e-85 yfjM S Psort location Cytoplasmic, score
LKAIADJA_04472 7.1e-186 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LKAIADJA_04473 2e-43 S YfzA-like protein
LKAIADJA_04474 5.3e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LKAIADJA_04475 5.2e-164 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LKAIADJA_04476 5e-184 corA P Mediates influx of magnesium ions
LKAIADJA_04477 9.8e-147 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
LKAIADJA_04478 4.9e-153 pdaA G deacetylase
LKAIADJA_04479 1.1e-26 yfjT
LKAIADJA_04480 5.4e-222 yfkA S YfkB-like domain
LKAIADJA_04481 2.5e-147 yfkC M Mechanosensitive ion channel
LKAIADJA_04482 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LKAIADJA_04483 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LKAIADJA_04484 1.8e-37 yaaB S Domain of unknown function (DUF370)
LKAIADJA_04485 5.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LKAIADJA_04486 2.4e-33 yaaA S S4 domain
LKAIADJA_04487 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LKAIADJA_04488 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LKAIADJA_04489 6.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LKAIADJA_04490 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LKAIADJA_04491 5.5e-107 jag S single-stranded nucleic acid binding R3H
LKAIADJA_04492 3.7e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LKAIADJA_04493 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LKAIADJA_04494 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
LKAIADJA_04495 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
LKAIADJA_04496 9.6e-74 S Bacterial PH domain
LKAIADJA_04497 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
LKAIADJA_04498 2.1e-149 spo0J K Belongs to the ParB family
LKAIADJA_04499 1.6e-111 yyaC S Sporulation protein YyaC
LKAIADJA_04500 8.1e-177 yyaD S Membrane
LKAIADJA_04501 2.3e-33 yyzM S protein conserved in bacteria
LKAIADJA_04502 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LKAIADJA_04503 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LKAIADJA_04504 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
LKAIADJA_04505 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LKAIADJA_04506 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LKAIADJA_04507 1.2e-143 xth 3.1.11.2 L exodeoxyribonuclease III
LKAIADJA_04508 8.9e-178 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
LKAIADJA_04509 1.4e-65 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LKAIADJA_04510 9.3e-90 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
LKAIADJA_04511 3.9e-243 EGP Major facilitator superfamily
LKAIADJA_04512 8e-168 yyaK S CAAX protease self-immunity
LKAIADJA_04513 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
LKAIADJA_04514 7.1e-248 tetL EGP Major facilitator Superfamily
LKAIADJA_04515 6.1e-105 yyaP 1.5.1.3 H RibD C-terminal domain
LKAIADJA_04516 1e-65 yyaQ S YjbR
LKAIADJA_04517 2.1e-91 yyaR K Acetyltransferase (GNAT) domain
LKAIADJA_04518 6.9e-94 yyaS S Membrane
LKAIADJA_04519 2.9e-70 yjcF S Acetyltransferase (GNAT) domain
LKAIADJA_04520 5.6e-77 yybA 2.3.1.57 K transcriptional
LKAIADJA_04521 1.6e-125 S Metallo-beta-lactamase superfamily
LKAIADJA_04522 3.6e-74 yybC
LKAIADJA_04523 1.4e-77 yjcF S Acetyltransferase (GNAT) domain
LKAIADJA_04524 2.6e-163 yybE K Transcriptional regulator
LKAIADJA_04525 2e-214 ynfM EGP Major facilitator Superfamily
LKAIADJA_04526 4e-121 yybG S Pentapeptide repeat-containing protein
LKAIADJA_04527 6.5e-66 yybH S SnoaL-like domain
LKAIADJA_04528 9e-123
LKAIADJA_04529 1.9e-169 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LKAIADJA_04530 4.9e-76 ykzC S Acetyltransferase (GNAT) family
LKAIADJA_04531 1.8e-150 suhB 3.1.3.25 G Inositol monophosphatase
LKAIADJA_04532 7.1e-26 ykzI
LKAIADJA_04533 2.1e-117 yktB S Belongs to the UPF0637 family
LKAIADJA_04534 2e-42 yktA S Belongs to the UPF0223 family
LKAIADJA_04535 1.3e-276 speA 4.1.1.19 E Arginine
LKAIADJA_04536 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
LKAIADJA_04537 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LKAIADJA_04538 2.4e-229 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LKAIADJA_04539 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LKAIADJA_04540 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LKAIADJA_04541 2e-115 recN L Putative cell-wall binding lipoprotein
LKAIADJA_04543 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LKAIADJA_04544 5.5e-147 ykrA S hydrolases of the HAD superfamily
LKAIADJA_04545 8.2e-31 ykzG S Belongs to the UPF0356 family
LKAIADJA_04546 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LKAIADJA_04547 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LKAIADJA_04548 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
LKAIADJA_04549 3.2e-155 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
LKAIADJA_04550 1.3e-240 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
LKAIADJA_04551 1.5e-43 abrB K of stationary sporulation gene expression
LKAIADJA_04552 7.7e-183 mreB D Rod-share determining protein MreBH
LKAIADJA_04553 1.1e-12 S Uncharacterized protein YkpC
LKAIADJA_04554 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
LKAIADJA_04555 2e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LKAIADJA_04556 1.7e-309 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LKAIADJA_04557 1.1e-38 ykoA
LKAIADJA_04558 2.4e-104 sipT 3.4.21.89 U Belongs to the peptidase S26 family
LKAIADJA_04559 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
LKAIADJA_04560 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
LKAIADJA_04561 3.1e-136 fruR K Transcriptional regulator
LKAIADJA_04562 8.1e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
LKAIADJA_04563 7.2e-124 macB V ABC transporter, ATP-binding protein
LKAIADJA_04564 4.3e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LKAIADJA_04565 1e-117 yknW S Yip1 domain
LKAIADJA_04566 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
LKAIADJA_04567 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
LKAIADJA_04568 8.3e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LKAIADJA_04569 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
LKAIADJA_04570 1.9e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
LKAIADJA_04571 1.2e-244 moeA 2.10.1.1 H molybdopterin
LKAIADJA_04572 1.4e-189 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LKAIADJA_04573 3.3e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
LKAIADJA_04574 1.9e-143 yknT
LKAIADJA_04575 4.2e-12
LKAIADJA_04576 8.6e-122 S Predicted permease
LKAIADJA_04577 1.7e-51 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
LKAIADJA_04578 2.3e-27
LKAIADJA_04579 8.2e-60 arsD S arsenical resistance operon
LKAIADJA_04580 1.7e-310 arsA 3.6.3.16 D ArgK protein
LKAIADJA_04581 0.0 cdr2 P Rhodanese Homology Domain
LKAIADJA_04582 1.5e-52 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
LKAIADJA_04583 3.6e-222 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LKAIADJA_04584 1.9e-73 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
LKAIADJA_04585 3.8e-66 L Resolvase, N terminal domain
LKAIADJA_04586 6.4e-63 cadC K Helix-turn-helix domain
LKAIADJA_04587 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
LKAIADJA_04588 1.8e-102 P Cadmium resistance transporter
LKAIADJA_04589 3.9e-56 L Resolvase, N terminal domain
LKAIADJA_04590 3.2e-142 3.6.1.3 S AAA domain
LKAIADJA_04591 2.2e-199 L COG2801 Transposase and inactivated derivatives
LKAIADJA_04592 1.1e-94 L DNA-invertase Bin3
LKAIADJA_04593 5e-72 L Resolvase, N terminal domain
LKAIADJA_04594 4.8e-231 P Sulfate permease
LKAIADJA_04595 1.7e-51 nhaX T Universal stress protein family
LKAIADJA_04596 8.7e-220 L COG2801 Transposase and inactivated derivatives
LKAIADJA_04597 3.4e-141 3.6.1.3 S AAA domain
LKAIADJA_04598 1.2e-95 L DNA-invertase Bin3
LKAIADJA_04600 6.1e-70 L Resolvase, N terminal domain
LKAIADJA_04601 1.1e-230 P Sulfate permease
LKAIADJA_04602 6.1e-54 nhaX T Universal stress protein family
LKAIADJA_04603 4.4e-140 P COG0477 Permeases of the major facilitator superfamily
LKAIADJA_04605 1.9e-177 fccB 1.8.5.4 S Pyridine nucleotide-disulphide oxidoreductase
LKAIADJA_04606 3.1e-256 baeB 3.1.2.6, 3.4.21.102 P Rhodanese Homology Domain
LKAIADJA_04607 3.2e-187 cdr OP Belongs to the sulfur carrier protein TusA family
LKAIADJA_04608 5e-38 yhjE S Metal-sensitive transcriptional repressor
LKAIADJA_04609 7.6e-111 yrkJ S membrane transporter protein
LKAIADJA_04610 1.8e-94 L DNA-invertase Bin3
LKAIADJA_04611 1.6e-28 C COG1145 Ferredoxin
LKAIADJA_04612 0.0 3.6.3.4 P P-type ATPase
LKAIADJA_04613 7.3e-256 mco Q Multicopper oxidase
LKAIADJA_04614 1.7e-88 ydhK M Protein of unknown function (DUF1541)
LKAIADJA_04615 1.3e-64 K WYL domain
LKAIADJA_04616 1.1e-74 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
LKAIADJA_04617 6.7e-42 M Is able to cleave peptidoglycan and affects clumping and separation of bacterial cells
LKAIADJA_04618 1.2e-146 yfkD S YfkD-like protein
LKAIADJA_04619 6.1e-183 cax P COG0387 Ca2 H antiporter
LKAIADJA_04620 1e-215 ycaD EGP COG0477 Permeases of the major facilitator superfamily
LKAIADJA_04621 1.3e-143 yihY S Belongs to the UPF0761 family
LKAIADJA_04622 2.4e-50 yfkI S gas vesicle protein
LKAIADJA_04623 7.4e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LKAIADJA_04624 1.3e-28 yfkK S Belongs to the UPF0435 family
LKAIADJA_04625 6.8e-207 ydiM EGP Major facilitator Superfamily
LKAIADJA_04626 1.1e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
LKAIADJA_04627 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
LKAIADJA_04628 1.5e-123 yfkO C nitroreductase
LKAIADJA_04629 6.7e-133 treR K transcriptional
LKAIADJA_04630 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
LKAIADJA_04631 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LKAIADJA_04632 7.6e-95 yfkQ EG Spore germination protein
LKAIADJA_04633 6e-67 yhdN S Domain of unknown function (DUF1992)
LKAIADJA_04634 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
LKAIADJA_04635 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
LKAIADJA_04636 2.1e-137 map 3.4.11.18 E Methionine aminopeptidase
LKAIADJA_04637 2.1e-42 yflH S Protein of unknown function (DUF3243)
LKAIADJA_04638 4.1e-19 yflI
LKAIADJA_04639 8.9e-18 yflJ S Protein of unknown function (DUF2639)
LKAIADJA_04640 6e-34 yflK S protein conserved in bacteria
LKAIADJA_04641 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
LKAIADJA_04642 3.3e-216 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
LKAIADJA_04643 1.8e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
LKAIADJA_04644 3.2e-226 citM C Citrate transporter
LKAIADJA_04645 4.8e-179 yflP S Tripartite tricarboxylate transporter family receptor
LKAIADJA_04646 1.3e-117 citT T response regulator
LKAIADJA_04647 3.7e-288 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
LKAIADJA_04648 5.5e-235 yflS P Sodium:sulfate symporter transmembrane region
LKAIADJA_04649 1.4e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
LKAIADJA_04650 7.6e-58 yflT S Heat induced stress protein YflT
LKAIADJA_04651 5e-24 S Protein of unknown function (DUF3212)
LKAIADJA_04652 2.3e-165 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
LKAIADJA_04653 4.7e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKAIADJA_04654 7.7e-164 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKAIADJA_04655 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
LKAIADJA_04656 5.5e-189 yfmJ S N-terminal domain of oxidoreductase
LKAIADJA_04658 6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
LKAIADJA_04659 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
LKAIADJA_04660 1.4e-141 ybbA S Putative esterase
LKAIADJA_04661 8.7e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKAIADJA_04662 1.8e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKAIADJA_04663 8.3e-163 feuA P Iron-uptake system-binding protein
LKAIADJA_04664 3.8e-306 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
LKAIADJA_04665 4.3e-236 ybbC 3.2.1.52 S protein conserved in bacteria
LKAIADJA_04666 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
LKAIADJA_04667 2e-252 yfeW 3.4.16.4 V Belongs to the UPF0214 family
LKAIADJA_04668 1.1e-232 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LKAIADJA_04669 5.1e-148 ybbH K transcriptional
LKAIADJA_04670 6.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LKAIADJA_04671 2.2e-28 ybbJ J acetyltransferase
LKAIADJA_04672 1.6e-76 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
LKAIADJA_04678 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
LKAIADJA_04679 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
LKAIADJA_04680 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LKAIADJA_04681 1.8e-222 ybbR S protein conserved in bacteria
LKAIADJA_04682 7.9e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LKAIADJA_04683 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LKAIADJA_04684 7.1e-172 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LKAIADJA_04685 9.8e-120 adaA 3.2.2.21 K Transcriptional regulator
LKAIADJA_04686 1.5e-100 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LKAIADJA_04687 7e-273 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
LKAIADJA_04688 0.0 ybcC S Belongs to the UPF0753 family
LKAIADJA_04689 1.2e-91 can 4.2.1.1 P carbonic anhydrase
LKAIADJA_04690 6.2e-45
LKAIADJA_04691 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
LKAIADJA_04692 5.1e-50 ybzH K Helix-turn-helix domain
LKAIADJA_04693 4.5e-203 ybcL EGP Major facilitator Superfamily
LKAIADJA_04694 1.2e-55
LKAIADJA_04695 7.6e-180 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LKAIADJA_04696 1.3e-122 T Transcriptional regulatory protein, C terminal
LKAIADJA_04697 1.8e-168 T His Kinase A (phospho-acceptor) domain
LKAIADJA_04698 7.9e-88 ytlQ
LKAIADJA_04699 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
LKAIADJA_04700 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
LKAIADJA_04701 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
LKAIADJA_04702 2e-45 ytzH S YtzH-like protein
LKAIADJA_04703 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LKAIADJA_04704 2.7e-149 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
LKAIADJA_04705 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
LKAIADJA_04706 1.1e-50 ytzB S small secreted protein
LKAIADJA_04707 4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
LKAIADJA_04708 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
LKAIADJA_04709 7.9e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
LKAIADJA_04710 4.8e-148 ytpQ S Belongs to the UPF0354 family
LKAIADJA_04711 2.8e-108 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LKAIADJA_04712 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
LKAIADJA_04713 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
LKAIADJA_04714 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LKAIADJA_04715 6.6e-17 ytxH S COG4980 Gas vesicle protein
LKAIADJA_04716 2.8e-54 ytxJ O Protein of unknown function (DUF2847)
LKAIADJA_04717 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
LKAIADJA_04718 3.8e-182 ccpA K catabolite control protein A
LKAIADJA_04719 2.1e-146 motA N flagellar motor
LKAIADJA_04720 8.9e-125 motS N Flagellar motor protein
LKAIADJA_04721 3.6e-224 acuC BQ histone deacetylase
LKAIADJA_04722 3.5e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
LKAIADJA_04723 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
LKAIADJA_04724 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LKAIADJA_04725 1.8e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LKAIADJA_04727 3.3e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LKAIADJA_04728 8.5e-307 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
LKAIADJA_04729 2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
LKAIADJA_04730 1e-108 yttP K Transcriptional regulator
LKAIADJA_04731 1e-153 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
LKAIADJA_04732 4.6e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LKAIADJA_04733 1.4e-237 brnQ E Component of the transport system for branched-chain amino acids
LKAIADJA_04734 1e-207 iscS2 2.8.1.7 E Cysteine desulfurase
LKAIADJA_04735 1e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LKAIADJA_04736 1e-28 sspB S spore protein
LKAIADJA_04737 1e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LKAIADJA_04738 0.0 ytcJ S amidohydrolase
LKAIADJA_04739 6.3e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LKAIADJA_04740 1.5e-178 sppA OU signal peptide peptidase SppA
LKAIADJA_04741 1.5e-86 yteJ S RDD family
LKAIADJA_04742 9.6e-108 ytfI S Protein of unknown function (DUF2953)
LKAIADJA_04743 1.5e-66 ytfJ S Sporulation protein YtfJ
LKAIADJA_04744 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LKAIADJA_04745 2.8e-161 ytxK 2.1.1.72 L DNA methylase
LKAIADJA_04746 4.1e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LKAIADJA_04747 3e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
LKAIADJA_04748 5.1e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
LKAIADJA_04749 8.9e-267 argH 4.3.2.1 E argininosuccinate lyase
LKAIADJA_04751 4.2e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKAIADJA_04752 1.7e-130 ytkL S Belongs to the UPF0173 family
LKAIADJA_04753 2.9e-173 ytlI K LysR substrate binding domain
LKAIADJA_04754 4.3e-100 ytmI K Acetyltransferase (GNAT) domain
LKAIADJA_04755 2.1e-151 tcyK ET Bacterial periplasmic substrate-binding proteins
LKAIADJA_04756 6.4e-148 tcyK M Bacterial periplasmic substrate-binding proteins
LKAIADJA_04757 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
LKAIADJA_04758 6.4e-120 tcyM U Binding-protein-dependent transport system inner membrane component
LKAIADJA_04759 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
LKAIADJA_04760 2.9e-182 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LKAIADJA_04761 7.9e-45 ytnI O COG0695 Glutaredoxin and related proteins
LKAIADJA_04762 1.8e-253 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LKAIADJA_04763 6.6e-119 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
LKAIADJA_04764 6.7e-237 ytnL 3.5.1.47 E hydrolase activity
LKAIADJA_04765 3.4e-158 ytnM S membrane transporter protein
LKAIADJA_04766 8e-241 ytoI K transcriptional regulator containing CBS domains
LKAIADJA_04767 2.4e-47 ytpI S YtpI-like protein
LKAIADJA_04768 2.3e-181 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
LKAIADJA_04769 9.2e-29
LKAIADJA_04770 8.2e-69 ytrI
LKAIADJA_04771 3.2e-56 ytrH S Sporulation protein YtrH
LKAIADJA_04772 0.0 dnaE 2.7.7.7 L DNA polymerase
LKAIADJA_04773 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
LKAIADJA_04774 2.7e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LKAIADJA_04775 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
LKAIADJA_04776 7.5e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LKAIADJA_04777 4.9e-311 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
LKAIADJA_04778 3.3e-62 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
LKAIADJA_04779 2.6e-192 ytvI S sporulation integral membrane protein YtvI
LKAIADJA_04780 4.7e-71 yeaL S membrane
LKAIADJA_04781 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
LKAIADJA_04782 4.1e-242 icd 1.1.1.42 C isocitrate
LKAIADJA_04783 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
LKAIADJA_04784 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKAIADJA_04785 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
LKAIADJA_04786 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LKAIADJA_04787 2.1e-154 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LKAIADJA_04788 2.5e-107 ytaF P Probably functions as a manganese efflux pump
LKAIADJA_04789 2.9e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LKAIADJA_04790 1.7e-159 ytbE S reductase
LKAIADJA_04791 2.8e-158 ytbD EGP Major facilitator Superfamily
LKAIADJA_04792 6.5e-15 ytcD K Transcriptional regulator
LKAIADJA_04793 2.8e-41 ytcD K Transcriptional regulator
LKAIADJA_04794 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LKAIADJA_04795 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LKAIADJA_04796 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LKAIADJA_04797 1.1e-264 dnaB L Membrane attachment protein
LKAIADJA_04798 3e-173 dnaI L Primosomal protein DnaI
LKAIADJA_04799 1.6e-109 ytxB S SNARE associated Golgi protein
LKAIADJA_04800 9.3e-158 ytxC S YtxC-like family
LKAIADJA_04801 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LKAIADJA_04802 5.2e-147 ysaA S HAD-hyrolase-like
LKAIADJA_04803 0.0 lytS 2.7.13.3 T Histidine kinase
LKAIADJA_04804 3.1e-130 lytT T COG3279 Response regulator of the LytR AlgR family
LKAIADJA_04805 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
LKAIADJA_04806 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
LKAIADJA_04808 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LKAIADJA_04809 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
LKAIADJA_04810 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LKAIADJA_04811 1.7e-44 ysdA S Membrane
LKAIADJA_04812 9.2e-68 ysdB S Sigma-w pathway protein YsdB
LKAIADJA_04813 5.8e-205 ysdC G COG1363 Cellulase M and related proteins
LKAIADJA_04814 7.9e-57 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
LKAIADJA_04815 1.2e-99 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
LKAIADJA_04816 1e-292 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
LKAIADJA_04817 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
LKAIADJA_04818 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
LKAIADJA_04819 2.3e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
LKAIADJA_04820 1.1e-220 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
LKAIADJA_04821 5.8e-252 araN G carbohydrate transport
LKAIADJA_04822 1.4e-167 araP G carbohydrate transport
LKAIADJA_04823 9.9e-144 araQ G transport system permease
LKAIADJA_04824 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
LKAIADJA_04825 0.0 cstA T Carbon starvation protein
LKAIADJA_04827 6.2e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
LKAIADJA_04828 3.6e-257 glcF C Glycolate oxidase
LKAIADJA_04829 2.2e-260 glcD 1.1.3.15 C Glycolate oxidase subunit
LKAIADJA_04830 5.9e-205 ysfB KT regulator
LKAIADJA_04831 2.6e-32 sspI S Belongs to the SspI family
LKAIADJA_04832 1.1e-130 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LKAIADJA_04833 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LKAIADJA_04834 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LKAIADJA_04835 2.4e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LKAIADJA_04836 2e-39 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LKAIADJA_04837 1.7e-85 cvpA S membrane protein, required for colicin V production
LKAIADJA_04838 0.0 polX L COG1796 DNA polymerase IV (family X)
LKAIADJA_04839 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LKAIADJA_04840 7.3e-68 yshE S membrane
LKAIADJA_04841 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LKAIADJA_04842 4.7e-100 fadR K Transcriptional regulator
LKAIADJA_04843 3.5e-135 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
LKAIADJA_04844 3.8e-134 etfB C Electron transfer flavoprotein
LKAIADJA_04845 5.1e-176 etfA C Electron transfer flavoprotein
LKAIADJA_04846 4.1e-302 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
LKAIADJA_04847 2e-52 trxA O Belongs to the thioredoxin family
LKAIADJA_04848 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LKAIADJA_04849 2e-214 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
LKAIADJA_04850 1.2e-79 yslB S Protein of unknown function (DUF2507)
LKAIADJA_04851 2.4e-107 sdhC C succinate dehydrogenase
LKAIADJA_04852 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
LKAIADJA_04853 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
LKAIADJA_04854 6.5e-78 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
LKAIADJA_04855 1.2e-17 gerE K Transcriptional regulator
LKAIADJA_04856 3.4e-48 yqaB E IrrE N-terminal-like domain
LKAIADJA_04857 2.9e-20
LKAIADJA_04859 7.2e-25 K sequence-specific DNA binding
LKAIADJA_04860 3.2e-13 K Helix-turn-helix XRE-family like proteins
LKAIADJA_04862 7e-45 S DNA binding
LKAIADJA_04863 3.2e-69
LKAIADJA_04867 3.5e-153 yqaJ L YqaJ-like viral recombinase domain
LKAIADJA_04868 8.1e-130 recT L RecT family
LKAIADJA_04869 1.4e-23 L DnaD domain protein
LKAIADJA_04870 1.9e-71 xkdC L IstB-like ATP binding protein
LKAIADJA_04872 4.9e-35 S YopX protein
LKAIADJA_04873 5.7e-53 S Protein of unknown function (DUF1064)
LKAIADJA_04875 3e-25 yqaO S Phage-like element PBSX protein XtrA
LKAIADJA_04877 4e-26
LKAIADJA_04881 1.4e-48 S dUTPase
LKAIADJA_04882 4e-08 S YopX protein
LKAIADJA_04887 8.9e-71 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
LKAIADJA_04889 2.6e-16 K Transcriptional regulator
LKAIADJA_04890 8.7e-89 S Domain of unknown function (DUF4868)
LKAIADJA_04891 7.8e-40
LKAIADJA_04892 2.9e-83 yqaS L DNA packaging
LKAIADJA_04893 4.4e-185 ps334 S Terminase-like family
LKAIADJA_04894 2.9e-156 S Phage portal protein, SPP1 Gp6-like
LKAIADJA_04895 1.3e-57 S Domain of unknown function (DUF4355)
LKAIADJA_04896 1.2e-123 S Phage capsid family
LKAIADJA_04898 1.4e-31 S Phage Mu protein F like protein
LKAIADJA_04899 2.5e-16 S Phage gp6-like head-tail connector protein
LKAIADJA_04900 3.9e-47
LKAIADJA_04901 1.5e-22
LKAIADJA_04902 3.1e-30
LKAIADJA_04903 1e-102 Z012_02110 S Protein of unknown function (DUF3383)
LKAIADJA_04904 3e-34
LKAIADJA_04905 7.6e-14
LKAIADJA_04906 2.2e-128 N phage tail tape measure protein
LKAIADJA_04907 3e-40 3.5.1.28 M LysM domain
LKAIADJA_04908 2.4e-30
LKAIADJA_04909 4e-88
LKAIADJA_04910 2.7e-23
LKAIADJA_04911 1.3e-23 S Protein of unknown function (DUF2634)
LKAIADJA_04912 1.8e-106 Z012_12235 S homolog of phage Mu protein gp47
LKAIADJA_04913 3.9e-60
LKAIADJA_04914 2.8e-38
LKAIADJA_04916 2.6e-15 xkdX
LKAIADJA_04917 5.4e-58 S Bacteriophage holin family
LKAIADJA_04918 6.3e-126 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
LKAIADJA_04919 4.9e-21
LKAIADJA_04921 1.3e-44 S YolD-like protein
LKAIADJA_04922 5.2e-167 L Recombinase
LKAIADJA_04923 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
LKAIADJA_04924 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
LKAIADJA_04925 8.5e-196 gerM S COG5401 Spore germination protein
LKAIADJA_04926 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LKAIADJA_04927 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LKAIADJA_04928 4.1e-92 ysnB S Phosphoesterase
LKAIADJA_04930 1.6e-130 ysnF S protein conserved in bacteria
LKAIADJA_04931 9.3e-170 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
LKAIADJA_04932 2.4e-75 ysnE K acetyltransferase
LKAIADJA_04934 0.0 ilvB 2.2.1.6 E Acetolactate synthase
LKAIADJA_04935 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
LKAIADJA_04936 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LKAIADJA_04937 1.9e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LKAIADJA_04938 5.7e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
LKAIADJA_04939 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LKAIADJA_04940 4e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LKAIADJA_04941 1.9e-186 ysoA H Tetratricopeptide repeat
LKAIADJA_04942 4.1e-226 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LKAIADJA_04943 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LKAIADJA_04944 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
LKAIADJA_04945 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LKAIADJA_04946 5.7e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
LKAIADJA_04947 1.4e-89 ysxD
LKAIADJA_04948 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LKAIADJA_04949 3.6e-146 hemX O cytochrome C
LKAIADJA_04950 8.7e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
LKAIADJA_04951 2.4e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
LKAIADJA_04952 2.8e-182 hemB 4.2.1.24 H Belongs to the ALAD family
LKAIADJA_04953 5.6e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
LKAIADJA_04954 7.3e-202 spoVID M stage VI sporulation protein D
LKAIADJA_04955 6.6e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LKAIADJA_04956 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LKAIADJA_04957 9.6e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
LKAIADJA_04958 1.5e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
LKAIADJA_04959 1.2e-161 spoIIB S Sporulation related domain
LKAIADJA_04960 1.1e-101 maf D septum formation protein Maf
LKAIADJA_04961 5.9e-126 radC E Belongs to the UPF0758 family
LKAIADJA_04962 1.8e-184 mreB D Rod shape-determining protein MreB
LKAIADJA_04963 1.1e-156 mreC M Involved in formation and maintenance of cell shape
LKAIADJA_04964 4.2e-84 mreD M shape-determining protein
LKAIADJA_04965 7.1e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
LKAIADJA_04966 4.7e-143 minD D Belongs to the ParA family
LKAIADJA_04967 1.1e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
LKAIADJA_04968 2e-160 spoIVFB S Stage IV sporulation protein
LKAIADJA_04969 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
LKAIADJA_04970 4.1e-56 ysxB J ribosomal protein
LKAIADJA_04971 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
LKAIADJA_04972 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
LKAIADJA_04973 4.3e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LKAIADJA_04974 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
LKAIADJA_04975 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
LKAIADJA_04976 2.3e-93 niaR S small molecule binding protein (contains 3H domain)
LKAIADJA_04977 5.9e-227 nifS 2.8.1.7 E Cysteine desulfurase
LKAIADJA_04978 3.4e-302 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
LKAIADJA_04979 2.9e-154 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
LKAIADJA_04980 9.1e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LKAIADJA_04981 5.2e-135 safA M spore coat assembly protein SafA
LKAIADJA_04982 6e-47 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LKAIADJA_04983 6.1e-126 yebC K transcriptional regulatory protein
LKAIADJA_04984 4.5e-261 alsT E Sodium alanine symporter
LKAIADJA_04985 1.5e-50 S Family of unknown function (DUF5412)
LKAIADJA_04987 6.5e-119 yrzF T serine threonine protein kinase
LKAIADJA_04988 4.8e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
LKAIADJA_04989 1.5e-252 csbX EGP Major facilitator Superfamily
LKAIADJA_04990 4.8e-93 bofC S BofC C-terminal domain
LKAIADJA_04991 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LKAIADJA_04992 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LKAIADJA_04993 2.6e-18 yrzS S Protein of unknown function (DUF2905)
LKAIADJA_04994 5.7e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LKAIADJA_04995 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LKAIADJA_04996 8e-39 yajC U Preprotein translocase subunit YajC
LKAIADJA_04997 3.8e-73 yrzE S Protein of unknown function (DUF3792)
LKAIADJA_04998 6.6e-111 yrbG S membrane
LKAIADJA_04999 2.4e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LKAIADJA_05000 1.6e-48 yrzD S Post-transcriptional regulator
LKAIADJA_05001 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LKAIADJA_05002 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
LKAIADJA_05003 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
LKAIADJA_05004 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
LKAIADJA_05005 2.3e-90 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LKAIADJA_05006 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LKAIADJA_05007 1.9e-69 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LKAIADJA_05008 5.9e-259 lytH 3.5.1.28 M COG3103 SH3 domain protein
LKAIADJA_05010 4.8e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
LKAIADJA_05011 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LKAIADJA_05012 9e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
LKAIADJA_05013 1.7e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
LKAIADJA_05014 1.2e-70 cymR K Transcriptional regulator
LKAIADJA_05015 5.7e-211 iscS 2.8.1.7 E Cysteine desulfurase
LKAIADJA_05016 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LKAIADJA_05017 1.4e-15 S COG0457 FOG TPR repeat
LKAIADJA_05018 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LKAIADJA_05019 6.6e-81 yrrD S protein conserved in bacteria
LKAIADJA_05020 9.8e-31 yrzR
LKAIADJA_05021 8e-08 S Protein of unknown function (DUF3918)
LKAIADJA_05022 7.6e-107 glnP P ABC transporter
LKAIADJA_05023 2.3e-108 gluC P ABC transporter
LKAIADJA_05024 2.5e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
LKAIADJA_05025 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
LKAIADJA_05026 2.5e-168 yrrI S AI-2E family transporter
LKAIADJA_05027 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LKAIADJA_05028 1.7e-41 yrzL S Belongs to the UPF0297 family
LKAIADJA_05029 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LKAIADJA_05030 1.2e-45 yrzB S Belongs to the UPF0473 family
LKAIADJA_05031 4.8e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LKAIADJA_05032 2.3e-119 yrrM 2.1.1.104 S O-methyltransferase
LKAIADJA_05033 7.8e-174 yegQ O Peptidase U32
LKAIADJA_05034 1.4e-245 yegQ O COG0826 Collagenase and related proteases
LKAIADJA_05035 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
LKAIADJA_05036 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LKAIADJA_05037 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
LKAIADJA_05038 4.2e-63 yrrS S Protein of unknown function (DUF1510)
LKAIADJA_05039 1e-25 yrzA S Protein of unknown function (DUF2536)
LKAIADJA_05040 1.2e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
LKAIADJA_05041 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LKAIADJA_05042 6.1e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
LKAIADJA_05043 9.1e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
LKAIADJA_05044 4.6e-35 yrhC S YrhC-like protein
LKAIADJA_05045 2.1e-77 yrhD S Protein of unknown function (DUF1641)
LKAIADJA_05046 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
LKAIADJA_05047 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
LKAIADJA_05048 1.8e-142 focA P Formate nitrite
LKAIADJA_05051 1.4e-95 yrhH Q methyltransferase
LKAIADJA_05052 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
LKAIADJA_05053 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
LKAIADJA_05054 9e-44 yrhK S YrhK-like protein
LKAIADJA_05055 0.0 yrhL I Acyltransferase family
LKAIADJA_05056 3.2e-150 rsiV S Protein of unknown function (DUF3298)
LKAIADJA_05057 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
LKAIADJA_05058 3.5e-149 yrhO K Archaeal transcriptional regulator TrmB
LKAIADJA_05059 1.1e-105 yrhP E LysE type translocator
LKAIADJA_05060 1.5e-253 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
LKAIADJA_05061 0.0 levR K PTS system fructose IIA component
LKAIADJA_05062 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
LKAIADJA_05063 3.1e-81 levE 2.7.1.202 G PTS system mannose fructose sorbose family
LKAIADJA_05064 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
LKAIADJA_05065 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
LKAIADJA_05066 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
LKAIADJA_05067 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
LKAIADJA_05068 1.8e-195 adhA 1.1.1.1 C alcohol dehydrogenase
LKAIADJA_05069 1.3e-25 yphJ 4.1.1.44 S peroxiredoxin activity
LKAIADJA_05070 4.3e-47 yraB K helix_turn_helix, mercury resistance
LKAIADJA_05071 4.8e-123 yrpD S Domain of unknown function, YrpD
LKAIADJA_05072 4.1e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
LKAIADJA_05073 1e-190 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
LKAIADJA_05074 5.5e-166 aadK G Streptomycin adenylyltransferase
LKAIADJA_05075 1.8e-254 xynT G MFS/sugar transport protein
LKAIADJA_05076 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
LKAIADJA_05077 3.1e-212 xylR GK ROK family
LKAIADJA_05078 2.4e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
LKAIADJA_05079 1.3e-290 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
LKAIADJA_05080 1.7e-111 yokF 3.1.31.1 L RNA catabolic process
LKAIADJA_05081 6.8e-254 iolT EGP Major facilitator Superfamily
LKAIADJA_05082 2.7e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LKAIADJA_05083 5.3e-83 yncE S Protein of unknown function (DUF2691)
LKAIADJA_05084 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
LKAIADJA_05085 5.2e-15
LKAIADJA_05088 1.9e-163 S Thymidylate synthase
LKAIADJA_05089 5.4e-32
LKAIADJA_05091 5.5e-127 S Domain of unknown function, YrpD
LKAIADJA_05094 7.9e-25 tatA U protein secretion
LKAIADJA_05095 3.7e-51
LKAIADJA_05096 2.6e-79 yndB S Activator of Hsp90 ATPase homolog 1-like protein
LKAIADJA_05099 9e-284 gerAA EG Spore germination protein
LKAIADJA_05100 1.1e-122 gerAB U Spore germination
LKAIADJA_05101 1.1e-59 gerAB U Spore germination
LKAIADJA_05102 5.1e-180 gerLC S Spore germination protein
LKAIADJA_05103 3.8e-153 yndG S DoxX-like family
LKAIADJA_05104 5.5e-113 yndH S Domain of unknown function (DUF4166)
LKAIADJA_05105 1.5e-305 yndJ S YndJ-like protein
LKAIADJA_05107 6.8e-136 yndL S Replication protein
LKAIADJA_05108 1.5e-92 yndM S Protein of unknown function (DUF2512)
LKAIADJA_05109 5.8e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
LKAIADJA_05110 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LKAIADJA_05111 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
LKAIADJA_05112 2.9e-111 yneB L resolvase
LKAIADJA_05113 1.3e-32 ynzC S UPF0291 protein
LKAIADJA_05114 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LKAIADJA_05115 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
LKAIADJA_05116 1.8e-28 yneF S UPF0154 protein
LKAIADJA_05117 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
LKAIADJA_05118 2.1e-126 ccdA O cytochrome c biogenesis protein
LKAIADJA_05119 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
LKAIADJA_05120 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
LKAIADJA_05121 3.9e-227 speA 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
LKAIADJA_05122 6e-106 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LKAIADJA_05123 3.7e-54 yaaQ S Cyclic-di-AMP receptor
LKAIADJA_05124 3.3e-164 holB 2.7.7.7 L DNA polymerase III
LKAIADJA_05125 4.4e-133 yaaT S Signal peptidase
LKAIADJA_05126 9.8e-50 yabA L Involved in initiation control of chromosome replication
LKAIADJA_05127 1.3e-131 yabB 2.1.1.223 S Methyltransferase small domain
LKAIADJA_05128 3.5e-36 yazA L endonuclease containing a URI domain
LKAIADJA_05129 1.2e-146 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LKAIADJA_05130 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LKAIADJA_05131 1.1e-146 tatD L Deoxyribonuclease
LKAIADJA_05132 1.6e-94 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LKAIADJA_05133 3.4e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LKAIADJA_05134 2.6e-42 veg S Biofilm formation stimulator VEG
LKAIADJA_05135 7.1e-158 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LKAIADJA_05136 1.2e-141 purR 2.4.2.7 F pur operon repressor
LKAIADJA_05137 2e-59 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
LKAIADJA_05138 1.7e-48 spoVG D Could be involved in septation
LKAIADJA_05139 1.1e-187 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LKAIADJA_05140 4.6e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LKAIADJA_05141 7.4e-70 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LKAIADJA_05142 1.4e-101 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LKAIADJA_05143 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LKAIADJA_05144 3.3e-254 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LKAIADJA_05145 1e-215 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
LKAIADJA_05146 6.7e-38 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
LKAIADJA_05147 3.9e-21 divIC D Cell-division initiation protein
LKAIADJA_05148 8.2e-48 yabR J RNA binding protein, contains ribosomal protein S1 domain
LKAIADJA_05149 2.5e-223 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LKAIADJA_05150 9.6e-92 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
LKAIADJA_05151 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LKAIADJA_05152 9.3e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LKAIADJA_05153 1.2e-171 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
LKAIADJA_05154 1.2e-141 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LKAIADJA_05155 3.6e-58 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LKAIADJA_05156 1.6e-74 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
LKAIADJA_05157 2.5e-283 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
LKAIADJA_05159 1e-07
LKAIADJA_05166 2.4e-273 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
LKAIADJA_05167 1.3e-75 ykvE K transcriptional
LKAIADJA_05168 1.5e-122 motB N Flagellar motor protein
LKAIADJA_05169 8.6e-137 motA N flagellar motor
LKAIADJA_05170 0.0 clpE O Belongs to the ClpA ClpB family
LKAIADJA_05171 2.4e-179 ykvI S membrane
LKAIADJA_05172 6.2e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LKAIADJA_05173 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
LKAIADJA_05174 2.4e-138 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
LKAIADJA_05175 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LKAIADJA_05176 2e-61 ykvN K Transcriptional regulator
LKAIADJA_05177 1.2e-132 IQ Enoyl-(Acyl carrier protein) reductase
LKAIADJA_05178 7.3e-233 ykvP 3.5.1.28 M Glycosyl transferases group 1
LKAIADJA_05179 3.5e-35 3.5.1.104 M LysM domain
LKAIADJA_05180 2.4e-162 G Glycosyl hydrolases family 18
LKAIADJA_05181 2.8e-45 ykvR S Protein of unknown function (DUF3219)
LKAIADJA_05182 6e-25 ykvS S protein conserved in bacteria
LKAIADJA_05183 2.8e-28
LKAIADJA_05184 4.8e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
LKAIADJA_05185 2.2e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LKAIADJA_05186 1.6e-88 stoA CO thiol-disulfide
LKAIADJA_05187 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
LKAIADJA_05188 1.1e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
LKAIADJA_05189 6.4e-179 ykvZ 5.1.1.1 K Transcriptional regulator
LKAIADJA_05190 7.6e-128 glcT K antiterminator
LKAIADJA_05191 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LKAIADJA_05192 2.1e-39 ptsH G phosphocarrier protein HPr
LKAIADJA_05193 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LKAIADJA_05194 7.2e-39 splA S Transcriptional regulator
LKAIADJA_05195 1.4e-200 splB 4.1.99.14 L Spore photoproduct lyase
LKAIADJA_05196 2e-126 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LKAIADJA_05197 4.4e-259 mcpC NT chemotaxis protein
LKAIADJA_05198 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
LKAIADJA_05199 2.4e-175 cryZ C Zinc-binding dehydrogenase
LKAIADJA_05200 3.5e-109 hxlA 4.1.2.43 G Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate
LKAIADJA_05201 7.1e-92 yhbO 3.5.1.124 S Intracellular protease
LKAIADJA_05202 0.0 uvrA2 L Excinuclease
LKAIADJA_05203 2.7e-224 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E Alcohol dehydrogenase GroES-like domain
LKAIADJA_05204 3.5e-13 yicL EG of the drug metabolite transporter (DMT) superfamily
LKAIADJA_05205 1.3e-57 K HxlR-like helix-turn-helix
LKAIADJA_05206 1.1e-105 hxlA 4.1.2.43 G Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate
LKAIADJA_05207 1.5e-92 hxlB 5.3.1.27 M SIS domain
LKAIADJA_05208 1.2e-103 L DNA-invertase Bin3
LKAIADJA_05209 3.8e-178 ycbJ S Phosphotransferase enzyme family
LKAIADJA_05210 2.9e-231 yheS_2 S ABC transporter
LKAIADJA_05211 4.7e-128 tnp1216 L COG3316 Transposase and inactivated derivatives
LKAIADJA_05212 2.1e-95 L Initiator Replication protein
LKAIADJA_05213 1.8e-36
LKAIADJA_05214 1.1e-151 P Co Zn Cd efflux system component
LKAIADJA_05215 1.6e-37 grxC O COG0695 Glutaredoxin and related proteins
LKAIADJA_05216 6.1e-42 csoR S Metal-sensitive transcriptional repressor
LKAIADJA_05217 0.0 copA 3.6.3.54 P P-type ATPase
LKAIADJA_05218 2.2e-31 copZ P mercury ion transmembrane transporter activity
LKAIADJA_05219 1.5e-126 S Membrane
LKAIADJA_05220 1.4e-95 J Acetyltransferase (GNAT) domain
LKAIADJA_05221 7.2e-128 L Reverse transcriptase (RNA-dependent DNA polymerase)
LKAIADJA_05223 3.6e-18 K Helix-turn-helix domain
LKAIADJA_05224 1.2e-42 cadX K helix_turn_helix, Arsenical Resistance Operon Repressor
LKAIADJA_05225 1e-97 cadD P Cadmium resistance transporter
LKAIADJA_05227 2.2e-27 L Replication protein
LKAIADJA_05228 3.3e-151 repA S Replication initiator protein A (RepA) N-terminus
LKAIADJA_05229 1.9e-57 S Protein of unknown function (DUF2568)
LKAIADJA_05230 1e-99 yrdC 3.5.1.19 Q Isochorismatase family
LKAIADJA_05231 1e-226 cypA C Cytochrome P450
LKAIADJA_05232 2.6e-40 yrdF K ribonuclease inhibitor
LKAIADJA_05233 1.1e-78 bkdR K helix_turn_helix ASNC type
LKAIADJA_05234 2.2e-91 azlC E AzlC protein
LKAIADJA_05235 5.6e-50 azlD E Branched-chain amino acid transport protein (AzlD)
LKAIADJA_05236 1.1e-226 brnQ E Component of the transport system for branched-chain amino acids
LKAIADJA_05237 5e-162 gltR K LysR substrate binding domain
LKAIADJA_05238 4.2e-65 yodA S tautomerase
LKAIADJA_05239 2.6e-153 czcD P COG1230 Co Zn Cd efflux system component
LKAIADJA_05240 3.6e-196 trkA P Oxidoreductase
LKAIADJA_05241 6.6e-159 yrdQ K Transcriptional regulator
LKAIADJA_05242 1.9e-170 yrdR EG EamA-like transporter family
LKAIADJA_05243 3.9e-16 S YrzO-like protein
LKAIADJA_05244 1.6e-233 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
LKAIADJA_05245 1.5e-82 bltD 2.3.1.57 K FR47-like protein
LKAIADJA_05246 3.5e-211 blt EGP Major facilitator Superfamily
LKAIADJA_05247 3.1e-150 bltR K helix_turn_helix, mercury resistance
LKAIADJA_05248 1.8e-104 yrkC G Cupin domain
LKAIADJA_05249 8.6e-21
LKAIADJA_05250 1e-38 yrkD S protein conserved in bacteria
LKAIADJA_05251 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
LKAIADJA_05252 4.2e-98 yrkF OP Belongs to the sulfur carrier protein TusA family
LKAIADJA_05253 9.3e-206 yrkH P Rhodanese Homology Domain
LKAIADJA_05254 5.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
LKAIADJA_05255 2.1e-111 yrkJ S membrane transporter protein
LKAIADJA_05256 8.6e-164 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
LKAIADJA_05257 5.3e-70 mepA V Multidrug transporter MatE
LKAIADJA_05258 1.9e-118 mepA V Multidrug transporter MatE
LKAIADJA_05259 3.3e-113 tetR3 K Transcriptional regulator
LKAIADJA_05260 8e-124 ykwD J protein with SCP PR1 domains
LKAIADJA_05261 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
LKAIADJA_05262 0.0 pilS 2.7.13.3 T Histidine kinase
LKAIADJA_05263 3.7e-221 patA 2.6.1.1 E Aminotransferase
LKAIADJA_05264 2.2e-15
LKAIADJA_05265 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
LKAIADJA_05266 1.7e-84 ykyB S YkyB-like protein
LKAIADJA_05267 4.8e-238 ykuC EGP Major facilitator Superfamily
LKAIADJA_05268 1.5e-86 ykuD S protein conserved in bacteria
LKAIADJA_05269 1.6e-165 ykuE S Metallophosphoesterase
LKAIADJA_05270 6.4e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKAIADJA_05271 0.0 3.2.1.132 M Putative peptidoglycan binding domain
LKAIADJA_05272 3.2e-124 M Peptidoglycan-binding domain 1 protein
LKAIADJA_05274 3.3e-233 ykuI T Diguanylate phosphodiesterase
LKAIADJA_05276 3.9e-37 ykuJ S protein conserved in bacteria
LKAIADJA_05277 4.4e-94 ykuK S Ribonuclease H-like
LKAIADJA_05278 3.9e-27 ykzF S Antirepressor AbbA
LKAIADJA_05280 4.7e-76 ykuL S CBS domain
LKAIADJA_05281 3.5e-168 ccpC K Transcriptional regulator
LKAIADJA_05282 1.7e-84 fld C Flavodoxin domain
LKAIADJA_05283 5.2e-175 ykuO
LKAIADJA_05284 1.6e-76 fld C Flavodoxin
LKAIADJA_05285 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LKAIADJA_05286 1.6e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LKAIADJA_05287 9e-37 ykuS S Belongs to the UPF0180 family
LKAIADJA_05288 2.6e-141 ykuT M Mechanosensitive ion channel
LKAIADJA_05289 4.3e-100 ykuU O Alkyl hydroperoxide reductase
LKAIADJA_05290 6.3e-81 ykuV CO thiol-disulfide
LKAIADJA_05291 5.8e-95 rok K Repressor of ComK
LKAIADJA_05292 1.8e-98 yciC S GTPases (G3E family)
LKAIADJA_05293 3.6e-112 yciC S GTPases (G3E family)
LKAIADJA_05294 4.2e-101 yciB M ErfK YbiS YcfS YnhG
LKAIADJA_05295 1.2e-171 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
LKAIADJA_05296 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
LKAIADJA_05297 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
LKAIADJA_05298 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LKAIADJA_05299 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LKAIADJA_05300 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
LKAIADJA_05301 1.5e-272 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
LKAIADJA_05302 4e-192 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
LKAIADJA_05303 8.5e-159 I alpha/beta hydrolase fold
LKAIADJA_05304 6.5e-138 ycgR S permeases
LKAIADJA_05305 4.8e-146 ycgQ S membrane
LKAIADJA_05306 6.2e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
LKAIADJA_05307 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LKAIADJA_05308 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
LKAIADJA_05309 5.1e-170 ycgM E Proline dehydrogenase
LKAIADJA_05310 1.2e-143 ycgL S Predicted nucleotidyltransferase
LKAIADJA_05311 9.4e-183 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
LKAIADJA_05312 5.6e-175 oxyR3 K LysR substrate binding domain
LKAIADJA_05313 1.4e-141 yafE Q ubiE/COQ5 methyltransferase family
LKAIADJA_05314 1.1e-29 S Protein of unknown function, DUF536
LKAIADJA_05315 4.7e-52 K HxlR-like helix-turn-helix
LKAIADJA_05316 2e-49 uvrA2 L Excinuclease
LKAIADJA_05317 1e-172 uvrA2 L Excinuclease
LKAIADJA_05318 2.9e-143 uvrA2 L Excinuclease
LKAIADJA_05319 4e-225 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LKAIADJA_05320 1.4e-222 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LKAIADJA_05321 4.7e-257 pgi 5.3.1.9 G Belongs to the GPI family
LKAIADJA_05322 7e-102 hxlA 4.1.2.43 G Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate
LKAIADJA_05323 7.8e-81 hxlB 5.3.1.27 M SIS domain
LKAIADJA_05324 1.9e-40 S hydrolase
LKAIADJA_05325 1.7e-87 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LKAIADJA_05326 3.3e-58 adaA 3.2.2.21 K sequence-specific DNA binding
LKAIADJA_05327 1.1e-81 alkA 3.2.2.21 L endonuclease III
LKAIADJA_05328 3e-83 4.1.99.14 L Elongator protein 3, MiaB family, Radical SAM
LKAIADJA_05329 3.4e-134 S protein conserved in bacteria (DUF2086)
LKAIADJA_05330 2.3e-101 mdaB S Flavodoxin-like fold
LKAIADJA_05331 6.1e-48 ycnE S Antibiotic biosynthesis monooxygenase
LKAIADJA_05332 5.3e-72 S SnoaL-like polyketide cyclase
LKAIADJA_05333 1.1e-95 hin_2 L Resolvase, N terminal domain
LKAIADJA_05334 1.9e-189 bdhA 1.1.1.303, 1.1.1.4 E Alcohol dehydrogenase GroES-like domain
LKAIADJA_05337 1.9e-186 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LKAIADJA_05338 9.5e-42 hsp O Belongs to the small heat shock protein (HSP20) family
LKAIADJA_05341 6.3e-50 L Replication protein
LKAIADJA_05342 1.6e-49 repA S Replication initiator protein A (RepA) N-terminus
LKAIADJA_05343 1.2e-52 flaG N flagellar protein FlaG
LKAIADJA_05344 7.7e-248 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LKAIADJA_05345 1.9e-68 fliS N flagellar protein FliS
LKAIADJA_05346 1.9e-08 fliT S bacterial-type flagellum organization
LKAIADJA_05347 4.6e-51
LKAIADJA_05348 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LKAIADJA_05349 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LKAIADJA_05350 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LKAIADJA_05351 7.1e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
LKAIADJA_05352 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
LKAIADJA_05353 1.6e-123 ftsE D cell division ATP-binding protein FtsE
LKAIADJA_05354 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
LKAIADJA_05355 2e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
LKAIADJA_05356 5.3e-56 swrA S Swarming motility protein
LKAIADJA_05357 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LKAIADJA_05358 7.9e-228 yvkA EGP Major facilitator Superfamily
LKAIADJA_05359 7e-101 yvkB K Transcriptional regulator
LKAIADJA_05360 0.0 yvkC 2.7.9.2 GT Phosphotransferase
LKAIADJA_05361 1.2e-30 csbA S protein conserved in bacteria
LKAIADJA_05362 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LKAIADJA_05363 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LKAIADJA_05364 5.8e-12
LKAIADJA_05365 3.5e-271 sufB O FeS cluster assembly
LKAIADJA_05366 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
LKAIADJA_05367 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LKAIADJA_05368 3.5e-244 sufD O assembly protein SufD
LKAIADJA_05369 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
LKAIADJA_05370 2.3e-47 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LKAIADJA_05371 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
LKAIADJA_05372 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
LKAIADJA_05373 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LKAIADJA_05374 3.2e-56 yusD S SCP-2 sterol transfer family
LKAIADJA_05375 6.2e-54 traF CO Thioredoxin
LKAIADJA_05376 1.1e-72 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
LKAIADJA_05377 1.1e-39 yusG S Protein of unknown function (DUF2553)
LKAIADJA_05378 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
LKAIADJA_05379 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
LKAIADJA_05380 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
LKAIADJA_05381 7.9e-216 fadA 2.3.1.16 I Belongs to the thiolase family
LKAIADJA_05382 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
LKAIADJA_05383 8.1e-09 S YuzL-like protein
LKAIADJA_05384 1.9e-164 fadM E Proline dehydrogenase
LKAIADJA_05385 5.1e-40
LKAIADJA_05386 5.4e-53 yusN M Coat F domain
LKAIADJA_05387 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
LKAIADJA_05388 4.2e-292 yusP P Major facilitator superfamily
LKAIADJA_05389 3.3e-59 yusQ S Tautomerase enzyme
LKAIADJA_05393 1.5e-109 istB2 L IstB-like ATP binding protein
LKAIADJA_05398 1.6e-198 3.1.21.3 L Domain of unknown function (DUF4942)
LKAIADJA_05400 3.6e-235
LKAIADJA_05404 0.0
LKAIADJA_05405 1.9e-35 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LKAIADJA_05407 2e-203 S Calcineurin-like phosphoesterase superfamily domain
LKAIADJA_05411 4.9e-17
LKAIADJA_05412 9.6e-109
LKAIADJA_05413 4e-18
LKAIADJA_05414 1.6e-35
LKAIADJA_05416 3.3e-70
LKAIADJA_05419 9.1e-68
LKAIADJA_05420 5.7e-78
LKAIADJA_05421 1.3e-72
LKAIADJA_05422 3.2e-59
LKAIADJA_05425 1.2e-45
LKAIADJA_05426 1.5e-35 S Domain of unknown function (DUF2479)
LKAIADJA_05427 2.1e-08
LKAIADJA_05428 1.6e-07 S Phage uncharacterised protein (Phage_XkdX)
LKAIADJA_05429 1.3e-98 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
LKAIADJA_05430 1.6e-53
LKAIADJA_05431 2.3e-56
LKAIADJA_05432 2.2e-190 xerH A Belongs to the 'phage' integrase family
LKAIADJA_05433 2.2e-22
LKAIADJA_05435 5.8e-110
LKAIADJA_05436 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LKAIADJA_05437 8.5e-86 S Phage tail protein
LKAIADJA_05438 5.2e-292 S Pfam Transposase IS66
LKAIADJA_05439 2.2e-119
LKAIADJA_05440 1e-183 M Pectate lyase superfamily protein
LKAIADJA_05441 5.5e-75 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
LKAIADJA_05442 4.4e-32 bhlA S BhlA holin family
LKAIADJA_05443 5.5e-40 S SPP1 phage holin
LKAIADJA_05444 3.4e-74 O protein disulfide oxidoreductase activity
LKAIADJA_05445 2.9e-240 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LKAIADJA_05446 1.2e-70 CO cell redox homeostasis
LKAIADJA_05447 0.0 V Peptidase C39 family
LKAIADJA_05450 1.5e-233 S impB/mucB/samB family C-terminal domain
LKAIADJA_05451 8.4e-54 S YolD-like protein
LKAIADJA_05455 6.8e-100 S aspartate phosphatase
LKAIADJA_05456 1.8e-91 yokK S SMI1 / KNR4 family
LKAIADJA_05457 8.2e-76 S SMI1-KNR4 cell-wall
LKAIADJA_05458 1.7e-172 yobL S Bacterial EndoU nuclease
LKAIADJA_05459 7.6e-65 G SMI1-KNR4 cell-wall
LKAIADJA_05460 1.9e-108 yokF 3.1.31.1 L RNA catabolic process
LKAIADJA_05461 5.8e-81 yhbS S family acetyltransferase
LKAIADJA_05463 2.4e-97 spoVK O stage V sporulation protein K
LKAIADJA_05464 2.8e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LKAIADJA_05465 1.7e-108 ymaB
LKAIADJA_05466 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LKAIADJA_05467 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LKAIADJA_05468 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
LKAIADJA_05469 4.5e-22 ymzA
LKAIADJA_05470 8.2e-23
LKAIADJA_05471 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
LKAIADJA_05472 3.5e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LKAIADJA_05473 2.1e-46 ymaF S YmaF family
LKAIADJA_05475 4.9e-51 ebrA P Small Multidrug Resistance protein
LKAIADJA_05476 6.2e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
LKAIADJA_05477 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
LKAIADJA_05478 2.1e-126 ymaC S Replication protein
LKAIADJA_05479 1e-119 aprX O Belongs to the peptidase S8 family
LKAIADJA_05480 3e-96 aprX O Belongs to the peptidase S8 family
LKAIADJA_05481 5.8e-160 ymaE S Metallo-beta-lactamase superfamily
LKAIADJA_05482 4.4e-61 ymzB
LKAIADJA_05483 1.1e-102 pksA K Transcriptional regulator
LKAIADJA_05484 1.1e-95 ymcC S Membrane
LKAIADJA_05485 2.2e-68 S Regulatory protein YrvL
LKAIADJA_05486 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LKAIADJA_05487 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LKAIADJA_05488 2.2e-88 cotE S Spore coat protein
LKAIADJA_05489 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
LKAIADJA_05490 6.5e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LKAIADJA_05491 7.2e-217 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
LKAIADJA_05492 2.8e-196 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
LKAIADJA_05493 1.2e-36 spoVS S Stage V sporulation protein S
LKAIADJA_05494 1.9e-152 ymdB S protein conserved in bacteria
LKAIADJA_05495 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
LKAIADJA_05496 4.4e-214 pbpX V Beta-lactamase
LKAIADJA_05497 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LKAIADJA_05498 2.8e-235 cinA 3.5.1.42 S Belongs to the CinA family
LKAIADJA_05499 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LKAIADJA_05500 2.1e-115 ymfM S protein conserved in bacteria
LKAIADJA_05501 2.7e-143 ymfK S Protein of unknown function (DUF3388)
LKAIADJA_05502 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
LKAIADJA_05503 7.8e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
LKAIADJA_05504 1.9e-239 ymfH S zinc protease
LKAIADJA_05505 2.3e-232 ymfF S Peptidase M16
LKAIADJA_05506 3.8e-205 ymfD EGP Major facilitator Superfamily
LKAIADJA_05507 1.4e-133 ymfC K Transcriptional regulator
LKAIADJA_05508 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
LKAIADJA_05509 4.4e-32 S YlzJ-like protein
LKAIADJA_05510 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
LKAIADJA_05511 5.6e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LKAIADJA_05512 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LKAIADJA_05513 1.1e-220 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
LKAIADJA_05514 3.2e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LKAIADJA_05515 1.4e-107 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
LKAIADJA_05516 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
LKAIADJA_05517 2.6e-42 ymxH S YlmC YmxH family
LKAIADJA_05518 4.4e-233 pepR S Belongs to the peptidase M16 family
LKAIADJA_05519 6.8e-181 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
LKAIADJA_05520 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
LKAIADJA_05521 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LKAIADJA_05522 2.3e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
LKAIADJA_05523 4.7e-171 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LKAIADJA_05524 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LKAIADJA_05525 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LKAIADJA_05526 3.1e-47 ylxQ J ribosomal protein
LKAIADJA_05527 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
LKAIADJA_05528 1.1e-203 nusA K Participates in both transcription termination and antitermination
LKAIADJA_05529 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
LKAIADJA_05530 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LKAIADJA_05531 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LKAIADJA_05532 7.7e-233 rasP M zinc metalloprotease
LKAIADJA_05533 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
LKAIADJA_05534 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
LKAIADJA_05535 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LKAIADJA_05536 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LKAIADJA_05537 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
LKAIADJA_05538 8.2e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LKAIADJA_05539 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
LKAIADJA_05540 3.1e-76 ylxL
LKAIADJA_05541 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LKAIADJA_05542 4.3e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
LKAIADJA_05543 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
LKAIADJA_05544 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
LKAIADJA_05545 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
LKAIADJA_05546 7.5e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
LKAIADJA_05547 4.1e-156 flhG D Belongs to the ParA family
LKAIADJA_05548 1.2e-200 flhF N Flagellar biosynthesis regulator FlhF
LKAIADJA_05549 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LKAIADJA_05550 2e-189 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LKAIADJA_05551 3.6e-132 fliR N Flagellar biosynthetic protein FliR
LKAIADJA_05552 6.4e-36 fliQ N Role in flagellar biosynthesis
LKAIADJA_05553 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
LKAIADJA_05554 1.6e-96 fliZ N Flagellar biosynthesis protein, FliO
LKAIADJA_05555 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
LKAIADJA_05556 1.5e-182 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LKAIADJA_05557 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
LKAIADJA_05558 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
LKAIADJA_05559 2.2e-137 flgG N Flagellar basal body rod
LKAIADJA_05560 1.7e-72 flgD N Flagellar basal body rod modification protein
LKAIADJA_05561 2.3e-220 fliK N Flagellar hook-length control protein
LKAIADJA_05562 3.8e-36 ylxF S MgtE intracellular N domain
LKAIADJA_05563 4.2e-69 fliJ N Flagellar biosynthesis chaperone
LKAIADJA_05564 7.2e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
LKAIADJA_05565 2.8e-105 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
LKAIADJA_05566 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
LKAIADJA_05567 2.9e-253 fliF N The M ring may be actively involved in energy transduction
LKAIADJA_05568 1.9e-31 fliE N Flagellar hook-basal body
LKAIADJA_05569 1.3e-73 flgC N Belongs to the flagella basal body rod proteins family
LKAIADJA_05570 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
LKAIADJA_05572 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LKAIADJA_05573 2.2e-249 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LKAIADJA_05574 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LKAIADJA_05575 2.5e-169 xerC L tyrosine recombinase XerC
LKAIADJA_05576 3.7e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LKAIADJA_05577 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LKAIADJA_05578 8e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
LKAIADJA_05579 3.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LKAIADJA_05580 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
LKAIADJA_05581 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
LKAIADJA_05582 2.7e-289 ylqG
LKAIADJA_05583 2.9e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LKAIADJA_05584 2.1e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LKAIADJA_05585 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LKAIADJA_05586 3.5e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
LKAIADJA_05587 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LKAIADJA_05588 1.4e-60 ylqD S YlqD protein
LKAIADJA_05589 4.5e-36 ylqC S Belongs to the UPF0109 family
LKAIADJA_05590 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
LKAIADJA_05591 3e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LKAIADJA_05592 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LKAIADJA_05593 1.6e-124 S Phosphotransferase enzyme family
LKAIADJA_05594 1.3e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LKAIADJA_05595 0.0 smc D Required for chromosome condensation and partitioning
LKAIADJA_05596 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LKAIADJA_05597 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
LKAIADJA_05598 6.1e-129 IQ reductase
LKAIADJA_05599 1e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
LKAIADJA_05600 8.1e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LKAIADJA_05601 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
LKAIADJA_05602 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LKAIADJA_05603 4.6e-155 sdaAA 4.3.1.17 E L-serine dehydratase
LKAIADJA_05604 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
LKAIADJA_05605 1.6e-299 yloV S kinase related to dihydroxyacetone kinase
LKAIADJA_05606 5.5e-59 asp S protein conserved in bacteria
LKAIADJA_05607 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
LKAIADJA_05608 2e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
LKAIADJA_05609 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
LKAIADJA_05610 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LKAIADJA_05611 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
LKAIADJA_05612 1.6e-140 stp 3.1.3.16 T phosphatase
LKAIADJA_05613 1.4e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
LKAIADJA_05614 1.6e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LKAIADJA_05615 6.5e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LKAIADJA_05616 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LKAIADJA_05617 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LKAIADJA_05618 1.4e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LKAIADJA_05619 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LKAIADJA_05620 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
LKAIADJA_05621 1.5e-40 ylzA S Belongs to the UPF0296 family
LKAIADJA_05622 2.4e-156 yloC S stress-induced protein
LKAIADJA_05623 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
LKAIADJA_05624 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
LKAIADJA_05625 1.6e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
LKAIADJA_05626 3.8e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
LKAIADJA_05627 1.1e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
LKAIADJA_05628 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
LKAIADJA_05629 5e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
LKAIADJA_05630 9.2e-179 cysP P phosphate transporter
LKAIADJA_05631 7.7e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
LKAIADJA_05632 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LKAIADJA_05633 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LKAIADJA_05634 2.7e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LKAIADJA_05635 5.9e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
LKAIADJA_05636 0.0 carB 6.3.5.5 F Belongs to the CarB family
LKAIADJA_05637 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
LKAIADJA_05638 6.4e-251 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LKAIADJA_05639 1.5e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
LKAIADJA_05640 2.7e-231 pyrP F Xanthine uracil
LKAIADJA_05641 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LKAIADJA_05642 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LKAIADJA_05643 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LKAIADJA_05644 1.3e-63 dksA T COG1734 DnaK suppressor protein
LKAIADJA_05645 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LKAIADJA_05646 2.6e-67 divIVA D Cell division initiation protein
LKAIADJA_05647 7.5e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
LKAIADJA_05648 1.1e-38 yggT S membrane
LKAIADJA_05649 5.1e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LKAIADJA_05650 6.5e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LKAIADJA_05651 7e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
LKAIADJA_05652 2.4e-37 ylmC S sporulation protein
LKAIADJA_05653 4.5e-249 argE 3.5.1.16 E Acetylornithine deacetylase
LKAIADJA_05654 3.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
LKAIADJA_05655 5.2e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LKAIADJA_05656 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LKAIADJA_05657 3.6e-171 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
LKAIADJA_05659 0.0 bpr O COG1404 Subtilisin-like serine proteases
LKAIADJA_05660 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LKAIADJA_05661 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LKAIADJA_05662 1.4e-57 sbp S small basic protein
LKAIADJA_05663 8.2e-117 ylxX S protein conserved in bacteria
LKAIADJA_05664 5.4e-103 ylxW S protein conserved in bacteria
LKAIADJA_05665 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LKAIADJA_05666 5.3e-167 murB 1.3.1.98 M cell wall formation
LKAIADJA_05667 9.7e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LKAIADJA_05668 5.7e-186 spoVE D Belongs to the SEDS family
LKAIADJA_05669 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LKAIADJA_05670 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LKAIADJA_05671 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LKAIADJA_05672 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
LKAIADJA_05673 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
LKAIADJA_05674 3.7e-44 ftsL D Essential cell division protein
LKAIADJA_05675 1.6e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LKAIADJA_05676 2.9e-78 mraZ K Belongs to the MraZ family
LKAIADJA_05677 1e-306 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
LKAIADJA_05678 5.7e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LKAIADJA_05679 1.5e-88 ylbP K n-acetyltransferase
LKAIADJA_05680 3.4e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
LKAIADJA_05681 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
LKAIADJA_05682 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
LKAIADJA_05684 2.8e-235 ylbM S Belongs to the UPF0348 family
LKAIADJA_05685 2.6e-186 ylbL T Belongs to the peptidase S16 family
LKAIADJA_05686 6.4e-137 ylbK S esterase of the alpha-beta hydrolase superfamily
LKAIADJA_05687 7.2e-220 ylbJ S Sporulation integral membrane protein YlbJ
LKAIADJA_05688 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LKAIADJA_05689 2.5e-95 rsmD 2.1.1.171 L Methyltransferase
LKAIADJA_05690 1.8e-27 ylbG S UPF0298 protein
LKAIADJA_05691 1.8e-75 ylbF S Belongs to the UPF0342 family
LKAIADJA_05692 6.7e-37 ylbE S YlbE-like protein
LKAIADJA_05693 4.1e-63 ylbD S Putative coat protein
LKAIADJA_05694 4.3e-200 ylbC S protein with SCP PR1 domains
LKAIADJA_05695 2.6e-74 ylbB T COG0517 FOG CBS domain
LKAIADJA_05696 7.7e-61 ylbA S YugN-like family
LKAIADJA_05697 7e-164 ctaG S cytochrome c oxidase
LKAIADJA_05698 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
LKAIADJA_05699 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
LKAIADJA_05700 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LKAIADJA_05701 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
LKAIADJA_05702 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
LKAIADJA_05703 2.2e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
LKAIADJA_05704 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LKAIADJA_05705 3.6e-211 ftsW D Belongs to the SEDS family
LKAIADJA_05706 8.7e-44 ylaN S Belongs to the UPF0358 family
LKAIADJA_05707 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
LKAIADJA_05708 1e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LKAIADJA_05709 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
LKAIADJA_05710 4.4e-88 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LKAIADJA_05711 2.5e-32 ylaI S protein conserved in bacteria
LKAIADJA_05712 4.2e-47 ylaH S YlaH-like protein
LKAIADJA_05713 0.0 typA T GTP-binding protein TypA
LKAIADJA_05714 8.2e-22 S Family of unknown function (DUF5325)
LKAIADJA_05715 2.6e-37 ylaE
LKAIADJA_05716 2e-11 sigC S Putative zinc-finger
LKAIADJA_05717 1.1e-87 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
LKAIADJA_05718 6.6e-41 ylaB
LKAIADJA_05719 0.0 ylaA
LKAIADJA_05720 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
LKAIADJA_05721 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LKAIADJA_05722 1.5e-292 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LKAIADJA_05723 8.2e-232 ytfP S HI0933-like protein
LKAIADJA_05724 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
LKAIADJA_05725 3.1e-26 yteV S Sporulation protein Cse60
LKAIADJA_05726 3.4e-115 yteU S Integral membrane protein
LKAIADJA_05727 5.4e-247 yteT S Oxidoreductase family, C-terminal alpha/beta domain
LKAIADJA_05728 5.1e-72 yteS G transport
LKAIADJA_05729 1.7e-220 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
LKAIADJA_05730 2.2e-171 lplB G COG4209 ABC-type polysaccharide transport system, permease component
LKAIADJA_05731 0.0 ytdP K Transcriptional regulator
LKAIADJA_05732 2.4e-286 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
LKAIADJA_05733 1.3e-149 ytcP G COG0395 ABC-type sugar transport system, permease component
LKAIADJA_05734 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
LKAIADJA_05735 2.4e-220 bioI 1.14.14.46 C Cytochrome P450
LKAIADJA_05736 2.1e-188 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LKAIADJA_05737 1.7e-125 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LKAIADJA_05738 2.8e-213 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
LKAIADJA_05739 5.6e-258 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
LKAIADJA_05740 5.5e-149 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
LKAIADJA_05741 9.1e-12 yqkE S Protein of unknown function (DUF3886)
LKAIADJA_05742 4.6e-171 yqkD S COG1073 Hydrolases of the alpha beta superfamily
LKAIADJA_05743 9.4e-39 yqkC S Protein of unknown function (DUF2552)
LKAIADJA_05744 2.8e-54 yqkB S Belongs to the HesB IscA family
LKAIADJA_05745 1.2e-191 yqkA K GrpB protein
LKAIADJA_05746 6.8e-59 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
LKAIADJA_05747 3.6e-87 yqjY K acetyltransferase
LKAIADJA_05748 1.7e-49 S YolD-like protein
LKAIADJA_05749 9.2e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LKAIADJA_05751 1.3e-221 yqjV G Major Facilitator Superfamily
LKAIADJA_05753 8.8e-71 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LKAIADJA_05754 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
LKAIADJA_05755 9.3e-261 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
LKAIADJA_05756 4.6e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
LKAIADJA_05757 7.7e-177 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
LKAIADJA_05758 6.4e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LKAIADJA_05759 0.0 rocB E arginine degradation protein
LKAIADJA_05760 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
LKAIADJA_05761 1.4e-144 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LKAIADJA_05762 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
LKAIADJA_05763 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LKAIADJA_05764 2.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LKAIADJA_05766 3.4e-183 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LKAIADJA_05767 1.7e-35 O Glutaredoxin
LKAIADJA_05768 1.1e-09
LKAIADJA_05769 3.6e-73 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
LKAIADJA_05774 4.7e-162 S Thymidylate synthase
LKAIADJA_05775 2e-30 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LKAIADJA_05777 7e-36
LKAIADJA_05779 6.8e-25 sspB S spore protein
LKAIADJA_05788 1e-94 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LKAIADJA_05790 5.3e-245 cisA2 L Recombinase
LKAIADJA_05791 8.7e-69 spoVK O stage V sporulation protein K
LKAIADJA_05792 2.1e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LKAIADJA_05793 9.7e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
LKAIADJA_05794 1.1e-68 glnR K transcriptional
LKAIADJA_05795 1e-259 glnA 6.3.1.2 E glutamine synthetase
LKAIADJA_05796 3.7e-74 L Belongs to the 'phage' integrase family
LKAIADJA_05798 5e-23 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
LKAIADJA_05799 2.6e-39 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
LKAIADJA_05800 1e-111 yfmS NT chemotaxis protein
LKAIADJA_05801 8.2e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LKAIADJA_05802 4.2e-240 yfnA E amino acid
LKAIADJA_05803 1.8e-130 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
LKAIADJA_05804 4.6e-206 fsr P COG0477 Permeases of the major facilitator superfamily
LKAIADJA_05805 1e-189 yfnD M Nucleotide-diphospho-sugar transferase
LKAIADJA_05806 2.7e-224 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
LKAIADJA_05807 7.1e-180 yfnF M Nucleotide-diphospho-sugar transferase
LKAIADJA_05808 1.9e-186 yfnG 4.2.1.45 M dehydratase
LKAIADJA_05809 1e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
LKAIADJA_05810 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
LKAIADJA_05811 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
LKAIADJA_05812 2.4e-195 yetN S Protein of unknown function (DUF3900)
LKAIADJA_05813 6.7e-167 ygxA S Nucleotidyltransferase-like
LKAIADJA_05814 9.5e-56 ygzB S UPF0295 protein
LKAIADJA_05815 4e-80 perR P Belongs to the Fur family
LKAIADJA_05816 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
LKAIADJA_05817 4e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
LKAIADJA_05818 8.7e-180 ygaE S Membrane
LKAIADJA_05819 1.8e-301 ygaD V ABC transporter
LKAIADJA_05820 1.3e-104 ygaC J Belongs to the UPF0374 family
LKAIADJA_05821 4.9e-48 ygaB S YgaB-like protein
LKAIADJA_05822 5.3e-08 sspE S Small, acid-soluble spore protein, gamma-type
LKAIADJA_05823 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKAIADJA_05824 6.9e-36 yfhS
LKAIADJA_05825 2.5e-210 mutY L A G-specific
LKAIADJA_05826 2.1e-185 yfhP S membrane-bound metal-dependent
LKAIADJA_05827 0.0 yfhO S Bacterial membrane protein YfhO
LKAIADJA_05828 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LKAIADJA_05829 1.3e-170 yfhM S Alpha beta hydrolase
LKAIADJA_05830 3.9e-50 yfhL S SdpI/YhfL protein family
LKAIADJA_05831 9.2e-92 batE T Bacterial SH3 domain homologues
LKAIADJA_05832 1.3e-63 hxlR K transcriptional
LKAIADJA_05833 8.9e-105 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
LKAIADJA_05834 1.9e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
LKAIADJA_05835 1.4e-176 tlpC 2.7.13.3 NT chemotaxis protein
LKAIADJA_05836 5.6e-69 nucA M Deoxyribonuclease NucA/NucB
LKAIADJA_05837 8.5e-69 nin S Competence protein J (ComJ)
LKAIADJA_05838 1.3e-50 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LKAIADJA_05839 3.7e-122 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LKAIADJA_05840 4.8e-87 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LKAIADJA_05841 7.8e-52 yckD S Protein of unknown function (DUF2680)
LKAIADJA_05842 5.8e-74 yckC S membrane
LKAIADJA_05844 1.7e-127 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
LKAIADJA_05845 1e-114 yecS P COG0765 ABC-type amino acid transport system, permease component
LKAIADJA_05846 4.3e-247 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LKAIADJA_05847 1.6e-54 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LKAIADJA_05848 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
LKAIADJA_05849 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
LKAIADJA_05851 7.2e-15 yycC K YycC-like protein
LKAIADJA_05852 2.1e-219 yeaN P COG2807 Cyanate permease
LKAIADJA_05853 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LKAIADJA_05854 2.2e-73 rplI J binds to the 23S rRNA
LKAIADJA_05855 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
LKAIADJA_05856 8.3e-160 yybS S membrane
LKAIADJA_05858 3.9e-84 cotF M Spore coat protein
LKAIADJA_05859 1.7e-66 ydeP3 K Transcriptional regulator
LKAIADJA_05860 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
LKAIADJA_05861 1.2e-58
LKAIADJA_05863 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
LKAIADJA_05864 6.3e-107 K TipAS antibiotic-recognition domain
LKAIADJA_05865 4.9e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
LKAIADJA_05866 3.6e-21 ywtC
LKAIADJA_05867 1.8e-217 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
LKAIADJA_05868 8.6e-70 pgsC S biosynthesis protein
LKAIADJA_05869 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
LKAIADJA_05870 2.1e-177 rbsR K transcriptional
LKAIADJA_05871 1.5e-158 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LKAIADJA_05872 2e-62 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
LKAIADJA_05873 2.3e-273 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
LKAIADJA_05874 9.3e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
LKAIADJA_05875 7e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
LKAIADJA_05876 9.6e-92 batE T Sh3 type 3 domain protein
LKAIADJA_05877 7.2e-37 ywsA S Protein of unknown function (DUF3892)
LKAIADJA_05878 4.4e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
LKAIADJA_05879 4.8e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
LKAIADJA_05880 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
LKAIADJA_05881 1.1e-169 alsR K LysR substrate binding domain
LKAIADJA_05882 2.9e-163 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LKAIADJA_05883 4.1e-124 ywrJ
LKAIADJA_05884 8.8e-77 cotB
LKAIADJA_05885 4.8e-23 cotB
LKAIADJA_05886 4e-206 cotH M Spore Coat
LKAIADJA_05887 1.1e-12
LKAIADJA_05888 8.4e-108 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LKAIADJA_05889 2.5e-53 S Domain of unknown function (DUF4181)
LKAIADJA_05890 9.7e-302 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
LKAIADJA_05891 8e-82 ywrC K Transcriptional regulator
LKAIADJA_05892 1.2e-103 ywrB P Chromate transporter
LKAIADJA_05893 9.9e-89 ywrA P COG2059 Chromate transport protein ChrA
LKAIADJA_05894 3e-117 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
LKAIADJA_05895 3.9e-25
LKAIADJA_05896 1.6e-81 ywqJ S Pre-toxin TG
LKAIADJA_05897 5.2e-17
LKAIADJA_05898 7.9e-43
LKAIADJA_05899 7.4e-213 ywqJ L nucleic acid phosphodiester bond hydrolysis
LKAIADJA_05900 2e-37 ywqI S Family of unknown function (DUF5344)
LKAIADJA_05901 1e-19 S Domain of unknown function (DUF5082)
LKAIADJA_05902 5.7e-85 ywqG S Domain of unknown function (DUF1963)
LKAIADJA_05903 9.5e-30 ywqG S Domain of unknown function (DUF1963)
LKAIADJA_05904 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
LKAIADJA_05905 7.9e-32 yaaL S Protein of unknown function (DUF2508)
LKAIADJA_05906 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LKAIADJA_05907 1.2e-36 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LKAIADJA_05908 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LKAIADJA_05909 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LKAIADJA_05910 1.4e-95 yaaI Q COG1335 Amidases related to nicotinamidase
LKAIADJA_05911 2.1e-209 yaaH M Glycoside Hydrolase Family
LKAIADJA_05912 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
LKAIADJA_05913 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
LKAIADJA_05914 1.3e-09
LKAIADJA_05915 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LKAIADJA_05916 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LKAIADJA_05917 2.8e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LKAIADJA_05918 7.5e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
LKAIADJA_05919 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
LKAIADJA_05920 1.1e-178 yaaC S YaaC-like Protein
LKAIADJA_05921 4.4e-42 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
LKAIADJA_05922 1.9e-107 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LKAIADJA_05923 3.5e-140 yitD 4.4.1.19 S synthase
LKAIADJA_05924 2.5e-121 comB 3.1.3.71 H Belongs to the ComB family
LKAIADJA_05925 5.5e-63 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
LKAIADJA_05926 1.5e-57 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
LKAIADJA_05927 5.4e-52 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
LKAIADJA_05928 5.1e-164 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
LKAIADJA_05929 1e-110 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
LKAIADJA_05930 1.2e-154 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LKAIADJA_05931 2e-35 mcbG S Pentapeptide repeats (9 copies)
LKAIADJA_05932 7.6e-277 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LKAIADJA_05933 1.2e-106 argO S Lysine exporter protein LysE YggA
LKAIADJA_05934 7e-92 yisT S DinB family
LKAIADJA_05935 5.4e-179 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
LKAIADJA_05936 1.4e-181 purR K helix_turn _helix lactose operon repressor
LKAIADJA_05937 1.6e-160 yisR K Transcriptional regulator
LKAIADJA_05938 5.2e-243 yisQ V Mate efflux family protein
LKAIADJA_05939 1.5e-117 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
LKAIADJA_05940 0.0 asnO 6.3.5.4 E Asparagine synthase
LKAIADJA_05941 1.3e-102 yisN S Protein of unknown function (DUF2777)
LKAIADJA_05942 0.0 wprA O Belongs to the peptidase S8 family
LKAIADJA_05943 3e-57 yisL S UPF0344 protein
LKAIADJA_05944 2.1e-171 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
LKAIADJA_05945 1.5e-53 cotH M Spore Coat
LKAIADJA_05946 1.5e-22 yisI S Spo0E like sporulation regulatory protein
LKAIADJA_05947 1.9e-33 gerPA S Spore germination protein
LKAIADJA_05948 4e-34 gerPB S cell differentiation
LKAIADJA_05949 5.3e-54 gerPC S Spore germination protein
LKAIADJA_05950 6.3e-24 gerPD S Spore germination protein
LKAIADJA_05951 3e-66 gerPE S Spore germination protein GerPE
LKAIADJA_05952 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
LKAIADJA_05953 3.1e-47 yisB V COG1403 Restriction endonuclease
LKAIADJA_05954 0.0 sbcC L COG0419 ATPase involved in DNA repair
LKAIADJA_05955 9.1e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
LKAIADJA_05956 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
LKAIADJA_05957 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
LKAIADJA_05958 6.4e-78 yhjR S Rubrerythrin
LKAIADJA_05959 0.0 S Sugar transport-related sRNA regulator N-term
LKAIADJA_05960 6.4e-213 EGP Transmembrane secretion effector
LKAIADJA_05961 1.9e-201 abrB S membrane
LKAIADJA_05962 5.5e-84 yhjM 5.1.1.1 K Transcriptional regulator
LKAIADJA_05963 2e-91 yhjM 5.1.1.1 K Transcriptional regulator
LKAIADJA_05964 5.4e-116 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
LKAIADJA_05965 5.9e-79 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
LKAIADJA_05966 9e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
LKAIADJA_05967 4.6e-199 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
LKAIADJA_05968 2e-214 glcP G Major Facilitator Superfamily
LKAIADJA_05969 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
LKAIADJA_05970 1.6e-282 yhjG CH FAD binding domain
LKAIADJA_05971 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
LKAIADJA_05972 9.1e-110 yhjE S SNARE associated Golgi protein
LKAIADJA_05973 6.7e-60 yhjD
LKAIADJA_05974 6.9e-27 yhjC S Protein of unknown function (DUF3311)
LKAIADJA_05975 1.4e-265 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LKAIADJA_05976 2.8e-39 yhjA S Excalibur calcium-binding domain
LKAIADJA_05977 1.4e-167 IQ Enoyl-(Acyl carrier protein) reductase
LKAIADJA_05978 4.2e-109 comK K Competence transcription factor
LKAIADJA_05979 1.3e-32 yhzC S IDEAL
LKAIADJA_05980 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKAIADJA_05981 1.6e-188 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
LKAIADJA_05982 7.4e-97 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
LKAIADJA_05983 8.8e-182 hemAT NT chemotaxis protein
LKAIADJA_05984 2.5e-90 bioY S BioY family
LKAIADJA_05985 9e-270 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
LKAIADJA_05986 5.5e-195 vraB 2.3.1.9 I Belongs to the thiolase family
LKAIADJA_05987 7.1e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
LKAIADJA_05988 3.8e-155 yfmC M Periplasmic binding protein
LKAIADJA_05989 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
LKAIADJA_05990 6.2e-76 VY92_01935 K acetyltransferase
LKAIADJA_05991 1.2e-203 aprE 3.4.21.62 O Belongs to the peptidase S8 family
LKAIADJA_05992 2.3e-240 yhfN 3.4.24.84 O Peptidase M48
LKAIADJA_05993 1.4e-63 yhfM
LKAIADJA_05994 3.1e-300 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
LKAIADJA_05995 2.9e-111 yhfK GM NmrA-like family
LKAIADJA_05996 4.9e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
LKAIADJA_05997 3.4e-140 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
LKAIADJA_05998 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LKAIADJA_05999 3.7e-72 3.4.13.21 S ASCH
LKAIADJA_06000 1.3e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
LKAIADJA_06001 1.1e-136 yhfC S Putative membrane peptidase family (DUF2324)
LKAIADJA_06002 3.3e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LKAIADJA_06003 1.9e-216 yhgE S YhgE Pip N-terminal domain protein
LKAIADJA_06004 4.6e-100 yhgD K Transcriptional regulator
LKAIADJA_06005 4.1e-267 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LKAIADJA_06006 3.6e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
LKAIADJA_06007 4.1e-203 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LKAIADJA_06008 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LKAIADJA_06009 8.4e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
LKAIADJA_06010 1.9e-34 1.15.1.2 C Rubrerythrin
LKAIADJA_06011 8.7e-246 yhfA C membrane
LKAIADJA_06012 2.8e-229 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
LKAIADJA_06013 1.4e-114 ecsC S EcsC protein family
LKAIADJA_06014 1.6e-214 ecsB U ABC transporter
LKAIADJA_06015 4.6e-137 ecsA V transporter (ATP-binding protein)
LKAIADJA_06016 1.1e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
LKAIADJA_06017 8.4e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LKAIADJA_06018 3.6e-80 trpP S Tryptophan transporter TrpP
LKAIADJA_06019 7e-39 yhaH S YtxH-like protein
LKAIADJA_06020 1e-113 hpr K Negative regulator of protease production and sporulation
LKAIADJA_06021 1.3e-54 yhaI S Protein of unknown function (DUF1878)
LKAIADJA_06022 1.1e-89 yhaK S Putative zincin peptidase
LKAIADJA_06023 1e-119 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LKAIADJA_06024 1.6e-21 yhaL S Sporulation protein YhaL
LKAIADJA_06025 5.8e-177 yhaM L Shows a 3'-5' exoribonuclease activity
LKAIADJA_06026 0.0 yhaN L AAA domain
LKAIADJA_06027 2e-222 yhaO L DNA repair exonuclease
LKAIADJA_06028 7.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
LKAIADJA_06029 1.2e-166 yhaQ S ABC transporter, ATP-binding protein
LKAIADJA_06030 1.1e-26 S YhzD-like protein
LKAIADJA_06031 4.6e-132 yhaR 5.3.3.18 I enoyl-CoA hydratase
LKAIADJA_06033 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
LKAIADJA_06034 8.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
LKAIADJA_06035 1.8e-292 hemZ H coproporphyrinogen III oxidase
LKAIADJA_06036 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
LKAIADJA_06037 4.4e-74 yhaZ L DNA alkylation repair enzyme
LKAIADJA_06038 5.3e-104 yhaZ L DNA alkylation repair enzyme
LKAIADJA_06039 9.5e-48 yheA S Belongs to the UPF0342 family
LKAIADJA_06040 6.3e-202 yheB S Belongs to the UPF0754 family
LKAIADJA_06041 4.3e-216 yheC HJ YheC/D like ATP-grasp
LKAIADJA_06042 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
LKAIADJA_06043 1.3e-36 yheE S Family of unknown function (DUF5342)
LKAIADJA_06044 6.3e-28 sspB S spore protein
LKAIADJA_06045 2.6e-109 yheG GM NAD(P)H-binding
LKAIADJA_06046 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
LKAIADJA_06047 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
LKAIADJA_06048 1.7e-83 nhaX T Belongs to the universal stress protein A family
LKAIADJA_06049 2.1e-228 nhaC C Na H antiporter
LKAIADJA_06050 1.8e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
LKAIADJA_06051 3.9e-148 yheN G deacetylase
LKAIADJA_06052 2.6e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
LKAIADJA_06053 5.6e-203 yhdY M Mechanosensitive ion channel
LKAIADJA_06055 2.3e-133 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LKAIADJA_06056 4.3e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LKAIADJA_06057 9.3e-43 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LKAIADJA_06058 4.6e-239 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
LKAIADJA_06059 2e-222 yhdR 2.6.1.1 E Aminotransferase
LKAIADJA_06060 9.1e-74 cueR K transcriptional
LKAIADJA_06061 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
LKAIADJA_06062 6.7e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
LKAIADJA_06063 1.4e-189 yhdN C Aldo keto reductase
LKAIADJA_06064 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
LKAIADJA_06065 6.6e-201 yhdL S Sigma factor regulator N-terminal
LKAIADJA_06066 8.1e-45 yhdK S Sigma-M inhibitor protein
LKAIADJA_06067 5.9e-76 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LKAIADJA_06068 2.1e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LKAIADJA_06069 1.5e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
LKAIADJA_06070 7.6e-250 yhdG E amino acid
LKAIADJA_06071 6e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKAIADJA_06072 2e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
LKAIADJA_06073 3.8e-162 citR K Transcriptional regulator
LKAIADJA_06074 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
LKAIADJA_06075 3.5e-255 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
LKAIADJA_06076 6.8e-262 ycgB S Stage V sporulation protein R
LKAIADJA_06077 9.6e-238 ygxB M Conserved TM helix
LKAIADJA_06078 1e-75 nsrR K Transcriptional regulator
LKAIADJA_06079 1e-183 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
LKAIADJA_06080 4.8e-54 yhdC S Protein of unknown function (DUF3889)
LKAIADJA_06081 3.6e-38 yhdB S YhdB-like protein
LKAIADJA_06082 4.2e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
LKAIADJA_06083 6.5e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LKAIADJA_06084 1.4e-212 yhcY 2.7.13.3 T Histidine kinase
LKAIADJA_06085 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
LKAIADJA_06086 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LKAIADJA_06087 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LKAIADJA_06088 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
LKAIADJA_06089 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LKAIADJA_06090 5.4e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LKAIADJA_06091 4.6e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LKAIADJA_06092 1e-119 yhcW 5.4.2.6 S hydrolase
LKAIADJA_06093 3.8e-67 yhcV S COG0517 FOG CBS domain
LKAIADJA_06094 9.3e-68 yhcU S Family of unknown function (DUF5365)
LKAIADJA_06095 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LKAIADJA_06096 2.1e-103 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
LKAIADJA_06097 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
LKAIADJA_06098 1.6e-96 yhcQ M Spore coat protein
LKAIADJA_06099 7e-160 yhcP
LKAIADJA_06100 2.1e-61 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LKAIADJA_06101 4.9e-41 yhcM
LKAIADJA_06102 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LKAIADJA_06103 8.4e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
LKAIADJA_06104 3.1e-150 metQ M Belongs to the nlpA lipoprotein family
LKAIADJA_06105 1e-30 cspB K Cold-shock protein
LKAIADJA_06106 2.5e-164 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LKAIADJA_06107 7.2e-164 yhcH V ABC transporter, ATP-binding protein
LKAIADJA_06108 8.8e-122 yhcG V ABC transporter, ATP-binding protein
LKAIADJA_06109 2.5e-59 yhcF K Transcriptional regulator
LKAIADJA_06110 3.6e-52
LKAIADJA_06111 2.8e-37 yhcC
LKAIADJA_06112 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
LKAIADJA_06113 1.5e-270 yhcA EGP Major facilitator Superfamily
LKAIADJA_06114 3.8e-87 yhbJ V COG1566 Multidrug resistance efflux pump
LKAIADJA_06115 2.2e-76 yhbI K DNA-binding transcription factor activity
LKAIADJA_06116 2.5e-225 yhbH S Belongs to the UPF0229 family
LKAIADJA_06117 0.0 prkA T Ser protein kinase
LKAIADJA_06118 2.1e-70 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
LKAIADJA_06119 4.2e-46 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
LKAIADJA_06120 2.7e-13 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
LKAIADJA_06121 2.1e-109 yhbD K Protein of unknown function (DUF4004)
LKAIADJA_06122 9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LKAIADJA_06123 4.1e-175 yhbB S Putative amidase domain
LKAIADJA_06124 6.6e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LKAIADJA_06125 3.3e-112 yhzB S B3/4 domain
LKAIADJA_06127 4.4e-29 K Transcriptional regulator
LKAIADJA_06128 1.3e-76 ygaO
LKAIADJA_06129 1.7e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LKAIADJA_06131 2.6e-216 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
LKAIADJA_06132 4.2e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
LKAIADJA_06133 7.3e-170 ssuA M Sulfonate ABC transporter
LKAIADJA_06134 1.1e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
LKAIADJA_06135 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
LKAIADJA_06137 7.6e-263 ygaK C Berberine and berberine like
LKAIADJA_06138 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LKAIADJA_06139 2.3e-130 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
LKAIADJA_06140 1.2e-26
LKAIADJA_06141 1.2e-43 spo0M S COG4326 Sporulation control protein
LKAIADJA_06142 8.6e-75 spo0M S COG4326 Sporulation control protein
LKAIADJA_06143 6.7e-292 ydaB IQ acyl-CoA ligase
LKAIADJA_06144 0.0 mtlR K transcriptional regulator, MtlR
LKAIADJA_06145 9.8e-174 ydhF S Oxidoreductase
LKAIADJA_06146 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
LKAIADJA_06147 1.4e-49 yczJ S biosynthesis
LKAIADJA_06149 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
LKAIADJA_06150 3.9e-131 kipR K Transcriptional regulator
LKAIADJA_06151 1.4e-184 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
LKAIADJA_06152 3.6e-134 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
LKAIADJA_06153 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
LKAIADJA_06154 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
LKAIADJA_06155 3.6e-140 ycsF S Belongs to the UPF0271 (lamB) family
LKAIADJA_06156 5.2e-136 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
LKAIADJA_06158 8.3e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LKAIADJA_06159 3e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
LKAIADJA_06160 2.2e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
LKAIADJA_06161 2e-116 ywqC M biosynthesis protein
LKAIADJA_06162 1.2e-17
LKAIADJA_06163 7.8e-307 ywqB S SWIM zinc finger
LKAIADJA_06164 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
LKAIADJA_06165 1.8e-156 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
LKAIADJA_06166 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
LKAIADJA_06167 2.2e-57 ssbB L Single-stranded DNA-binding protein
LKAIADJA_06168 3.8e-66 ywpG
LKAIADJA_06169 1.1e-66 ywpF S YwpF-like protein
LKAIADJA_06170 2.4e-29 KLT Protein tyrosine kinase
LKAIADJA_06171 4.3e-11 S YolD-like protein
LKAIADJA_06172 1.9e-36
LKAIADJA_06173 9e-19
LKAIADJA_06175 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
LKAIADJA_06176 6.3e-141 IQ Enoyl-(Acyl carrier protein) reductase
LKAIADJA_06178 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
LKAIADJA_06179 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
LKAIADJA_06180 5.6e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
LKAIADJA_06181 5.9e-49 yjdF S Protein of unknown function (DUF2992)
LKAIADJA_06182 3e-290 ybeC E amino acid
LKAIADJA_06183 4.9e-41 ybyB
LKAIADJA_06184 6.6e-245 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
LKAIADJA_06185 7.5e-149 ybxI 3.5.2.6 V beta-lactamase
LKAIADJA_06186 4.9e-30 ybxH S Family of unknown function (DUF5370)
LKAIADJA_06187 3.1e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
LKAIADJA_06188 8.4e-257 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
LKAIADJA_06189 2.4e-212 ybdO S Domain of unknown function (DUF4885)
LKAIADJA_06190 7.7e-152 ybdN
LKAIADJA_06191 3.9e-139 KLT Protein tyrosine kinase
LKAIADJA_06192 3.9e-176 yfiY P ABC transporter substrate-binding protein
LKAIADJA_06193 9.9e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKAIADJA_06194 4.4e-170 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKAIADJA_06195 5.3e-164 yfhB 5.3.3.17 S PhzF family
LKAIADJA_06196 3.9e-107 yfhC C nitroreductase
LKAIADJA_06197 2.1e-25 yfhD S YfhD-like protein
LKAIADJA_06199 6e-171 yfhF S nucleoside-diphosphate sugar epimerase
LKAIADJA_06200 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
LKAIADJA_06201 9.7e-52 yfhH S Protein of unknown function (DUF1811)
LKAIADJA_06203 5.6e-209 yfhI EGP Major facilitator Superfamily
LKAIADJA_06204 6.2e-20 sspK S reproduction
LKAIADJA_06205 1.3e-44 yfhJ S WVELL protein
LKAIADJA_06206 5.7e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
LKAIADJA_06207 3.4e-94 M1-753 M FR47-like protein
LKAIADJA_06208 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
LKAIADJA_06209 4.2e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
LKAIADJA_06210 3.9e-84 yuaE S DinB superfamily
LKAIADJA_06211 7.4e-106 yuaD
LKAIADJA_06212 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
LKAIADJA_06213 1.2e-280 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
LKAIADJA_06214 5.5e-95 yuaC K Belongs to the GbsR family
LKAIADJA_06215 2.2e-91 yuaB
LKAIADJA_06216 1.1e-89 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKAIADJA_06217 1.2e-249 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKAIADJA_06218 1.9e-198 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
LKAIADJA_06219 7.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LKAIADJA_06220 1.9e-209 yfmO EGP Major facilitator Superfamily
LKAIADJA_06221 1.4e-69 yfmP K transcriptional
LKAIADJA_06222 5.7e-74 yfmQ S Uncharacterised protein from bacillus cereus group
LKAIADJA_06223 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LKAIADJA_06224 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LKAIADJA_06225 2.5e-74 lrpC K Transcriptional regulator
LKAIADJA_06226 3.3e-46 ydzA EGP Major facilitator Superfamily
LKAIADJA_06227 1e-137 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
LKAIADJA_06228 2e-76 ydaG 1.4.3.5 S general stress protein
LKAIADJA_06229 3.6e-102 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LKAIADJA_06230 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
LKAIADJA_06231 2e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKAIADJA_06232 2.2e-97 ydaC Q Methyltransferase domain
LKAIADJA_06233 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
LKAIADJA_06234 1.4e-130 ythP V ABC transporter
LKAIADJA_06235 1.3e-202 ythQ U Bacterial ABC transporter protein EcsB
LKAIADJA_06236 2.1e-225 pbuO S permease
LKAIADJA_06237 3.9e-270 pepV 3.5.1.18 E Dipeptidase
LKAIADJA_06238 1.5e-172 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
LKAIADJA_06239 3e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LKAIADJA_06240 2.6e-50 ytlQ
LKAIADJA_06241 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LKAIADJA_06242 2.7e-54 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LKAIADJA_06243 9.8e-308 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LKAIADJA_06244 6.3e-88 Z012_06855 S (GNAT) family
LKAIADJA_06245 3e-125 treR K trehalose operon transcriptional repressor
LKAIADJA_06246 0.0 treC 3.2.1.93 GH13 G Alpha-amylase domain
LKAIADJA_06247 4.9e-244 treP 2.7.1.201 G PTS system
LKAIADJA_06248 3.3e-08
LKAIADJA_06249 9.1e-278 gltD 1.4.1.13, 1.4.1.14 C glutamate synthase
LKAIADJA_06250 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E Glutamate synthase
LKAIADJA_06251 1e-146 gltC K Transcriptional regulator
LKAIADJA_06252 1.2e-189 yibE S YibE F-like protein
LKAIADJA_06253 9.6e-125 yibF S YibE F-like protein
LKAIADJA_06254 1.8e-97
LKAIADJA_06255 4.3e-72 utp1 2.3.1.128, 2.7.1.48, 3.2.2.10, 3.6.1.55 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
LKAIADJA_06256 1.3e-53 utp1 2.3.1.128, 2.7.1.48, 3.2.2.10, 3.6.1.55 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
LKAIADJA_06257 3e-41
LKAIADJA_06258 5.1e-144 cwlS 3.5.1.28 CBM50 M Peptidoglycan hydrolase involved in the splitting of the septum during cell division
LKAIADJA_06259 1.1e-125 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase
LKAIADJA_06260 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
LKAIADJA_06261 5.8e-65 S Protein of unknown function (DUF2000)
LKAIADJA_06262 7.4e-74 E LysE type translocator
LKAIADJA_06263 7e-136 K AraC family transcriptional regulator
LKAIADJA_06264 1.5e-231 lip 3.1.1.3 D acetyltransferases and hydrolases with the alpha beta hydrolase fold
LKAIADJA_06265 1.6e-201 S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
LKAIADJA_06266 3.4e-207 brnQ U Component of the transport system for branched-chain amino acids
LKAIADJA_06267 3.5e-61 frataxin S Domain of unknown function (DU1801)
LKAIADJA_06268 2.2e-123 est 3.1.1.1 S Serine aminopeptidase, S33
LKAIADJA_06269 2.4e-199 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E Aminotransferase class-V
LKAIADJA_06270 7.4e-201 yeaN P transporter
LKAIADJA_06271 6.9e-170 arcC 2.7.2.2 E Belongs to the carbamate kinase family
LKAIADJA_06272 8e-132 S Protein of unknown function (DUF2877)
LKAIADJA_06273 8.5e-232 sucD 6.2.1.5 C Protein of unknown function (DUF1116)
LKAIADJA_06274 0.0 sucD 6.2.1.5 C CoA-ligase
LKAIADJA_06275 1.9e-197 allD 1.1.1.350 C Malate/L-lactate dehydrogenase
LKAIADJA_06276 1.9e-189 allD 1.1.1.350 C Malate/L-lactate dehydrogenase
LKAIADJA_06277 2.4e-152 ylbA 3.5.3.26 S Cupin domain
LKAIADJA_06278 1.8e-231 allC 3.5.1.6, 3.5.1.87, 3.5.3.9 E Peptidase family M28
LKAIADJA_06279 3.3e-139 4.2.99.20 I alpha/beta hydrolase fold
LKAIADJA_06280 5.2e-197 3.5.1.6, 3.5.1.87, 3.5.3.9 E Peptidase family M28
LKAIADJA_06281 7.5e-98 yhfR 3.1.3.73 G Phosphoglycerate mutase family
LKAIADJA_06282 2.6e-184 agcS_1 E COG1115 Na alanine symporter
LKAIADJA_06283 4.7e-260 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
LKAIADJA_06284 4.3e-275 ybbW FH Permease for cytosine/purines, uracil, thiamine, allantoin
LKAIADJA_06285 2.8e-288 pucR QT Purine catabolism regulatory protein-like family
LKAIADJA_06286 9e-238 EGP Major facilitator Superfamily
LKAIADJA_06287 7.9e-31 K 'Cold-shock' DNA-binding domain
LKAIADJA_06288 2.7e-62 S Protein of unknown function (DUF1093)
LKAIADJA_06289 1.6e-46
LKAIADJA_06291 1.7e-22
LKAIADJA_06293 2.3e-23
LKAIADJA_06294 3.9e-62 S LPXTG cell wall anchor motif
LKAIADJA_06295 4.8e-28
LKAIADJA_06296 7.5e-26
LKAIADJA_06297 2.1e-73 ohr O response to oxidative stress
LKAIADJA_06298 7.3e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
LKAIADJA_06299 2.8e-271 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
LKAIADJA_06300 2.8e-227 pbuX F xanthine
LKAIADJA_06301 5.7e-90 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LKAIADJA_06302 2.6e-60 S Heat induced stress protein YflT
LKAIADJA_06303 2.2e-114
LKAIADJA_06304 2.8e-47 A protein ubiquitination
LKAIADJA_06305 5.3e-235 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LKAIADJA_06306 4.2e-07
LKAIADJA_06307 6.1e-152 sdaAA 4.3.1.17 E L-serine dehydratase
LKAIADJA_06308 2.5e-97 sdaAB 4.3.1.17 E L-serine dehydratase
LKAIADJA_06309 3.5e-159 pfoR S COG1299 Phosphotransferase system, fructose-specific IIC component
LKAIADJA_06310 1.6e-100
LKAIADJA_06311 3.4e-135 nfrA 1.5.1.38, 1.5.1.39 C Reduces FMN, organic nitro compounds and disulfide DTNB. Involved in maintenance of the cellular redox state and the disulfide stress response
LKAIADJA_06312 0.0 katE 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
LKAIADJA_06313 1e-57 K Bacteriophage CI repressor helix-turn-helix domain
LKAIADJA_06314 1.1e-119 KT LytTr DNA-binding domain
LKAIADJA_06315 3e-124 V AAA domain, putative AbiEii toxin, Type IV TA system
LKAIADJA_06316 4.6e-49 V Transport permease protein
LKAIADJA_06317 1e-107 ahpC 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LKAIADJA_06318 2.2e-279 ahpF O Alkyl hydroperoxide reductase
LKAIADJA_06319 6.3e-79
LKAIADJA_06320 7.9e-29
LKAIADJA_06321 7.9e-100 3.1.3.73, 5.4.2.11 G Phosphoglycerate mutase family
LKAIADJA_06322 3e-36 yvlA
LKAIADJA_06323 5.7e-88 MA20_06410 E LysE type translocator
LKAIADJA_06324 3e-45 ykkD P Small Multidrug Resistance protein
LKAIADJA_06325 3.2e-46 ykkC P Multidrug resistance protein
LKAIADJA_06326 1e-31
LKAIADJA_06327 8.9e-18 K Acetyltransferase (GNAT) domain
LKAIADJA_06328 6.1e-19
LKAIADJA_06329 6.6e-203 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LKAIADJA_06330 7.7e-71 ywnA K Transcriptional regulator
LKAIADJA_06331 5.6e-60 S Activator of Hsp90 ATPase homolog 1-like protein
LKAIADJA_06332 3.5e-121 ymaC S Poly-gamma-glutamate hydrolase
LKAIADJA_06333 2e-212 trkH P Potassium uptake protein, integral membrane component, KtrB
LKAIADJA_06334 2.1e-27
LKAIADJA_06335 9.6e-60
LKAIADJA_06336 1.3e-174 CP_0155 3.2.1.96, 3.5.1.28 GH73 M Ami_2
LKAIADJA_06337 2.2e-19
LKAIADJA_06338 5.1e-16 ydcG K Helix-turn-helix
LKAIADJA_06339 5.9e-80 yncA 2.3.1.183 M Acetyltransferase (GNAT) domain
LKAIADJA_06340 2.6e-89
LKAIADJA_06342 2.3e-31
LKAIADJA_06343 4e-33
LKAIADJA_06346 6.9e-22
LKAIADJA_06347 4e-10
LKAIADJA_06348 1.5e-20
LKAIADJA_06350 7.8e-41
LKAIADJA_06352 3.4e-74 yvbK 3.1.3.25 K Acetyltransferase (GNAT) domain
LKAIADJA_06353 4.2e-11
LKAIADJA_06354 4.5e-69 S Stage II sporulation protein M
LKAIADJA_06356 1.6e-89
LKAIADJA_06359 1.8e-38 polC_1 2.7.7.7 L DNA-directed DNA polymerase activity
LKAIADJA_06360 1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LKAIADJA_06361 3.5e-67 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LKAIADJA_06362 3e-50 rpsF J Binds together with S18 to 16S ribosomal RNA
LKAIADJA_06363 5e-145 M Glycosyl hydrolases family 25
LKAIADJA_06364 9.7e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LKAIADJA_06365 8e-31 yyzM S Bacterial protein of unknown function (DUF951)
LKAIADJA_06366 2.1e-104 ykuT M Transporter, small conductance mechanosensitive ion channel MscS family protein
LKAIADJA_06367 3.7e-70 ybcI S Uncharacterized conserved protein (DUF2294)
LKAIADJA_06368 0.0 ybcC S Belongs to the UPF0753 family
LKAIADJA_06369 1.3e-266 ndhF 1.6.5.3 CP Proton-conducting membrane transporter
LKAIADJA_06370 6.4e-71 S ABC-2 family transporter protein
LKAIADJA_06371 9.9e-152 V ABC transporter, ATP-binding protein
LKAIADJA_06372 1.3e-186 bacI V MacB-like periplasmic core domain
LKAIADJA_06373 3.3e-121 V ABC transporter, ATP-binding protein
LKAIADJA_06374 6.2e-140 M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LKAIADJA_06375 7.8e-90 yknW S Yip1 domain
LKAIADJA_06376 2.9e-298 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LKAIADJA_06377 2e-163
LKAIADJA_06378 3.3e-245 EGP Major facilitator Superfamily
LKAIADJA_06379 6.8e-45 yflT S Heat induced stress protein YflT
LKAIADJA_06380 1.1e-49
LKAIADJA_06381 1.2e-74 guaD 3.5.4.33 FJ MafB19-like deaminase
LKAIADJA_06382 3.6e-68 3.6.1.27 I PAP2 superfamily
LKAIADJA_06383 5.6e-193 ftsW D Belongs to the SEDS family
LKAIADJA_06384 1.4e-57 Q ubiE/COQ5 methyltransferase family
LKAIADJA_06386 4.1e-220 solA 1.5.3.1 E FAD dependent oxidoreductase
LKAIADJA_06387 1.6e-189 argE 3.5.1.18 E Acetylornithine deacetylase
LKAIADJA_06388 6.6e-143 yrdQ K LysR substrate binding domain
LKAIADJA_06389 1.3e-139 add 3.5.4.4 F Adenosine/AMP deaminase
LKAIADJA_06391 2.4e-107 cysC 2.7.1.25 F Catalyzes the synthesis of activated sulfate
LKAIADJA_06392 2e-219 sat 2.7.7.4 H Belongs to the sulfate adenylyltransferase family
LKAIADJA_06393 1.9e-156 ytnM S membrane transporter protein
LKAIADJA_06394 6.8e-94 cysG 1.3.1.76, 4.99.1.4 H COG1648 Siroheme synthase (precorrin-2 oxidase ferrochelatase domain)
LKAIADJA_06395 9.9e-124 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S CbiX
LKAIADJA_06396 9.7e-138 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
LKAIADJA_06397 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 H Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
LKAIADJA_06398 0.0 cysJ 1.8.1.2 C Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LKAIADJA_06399 1.2e-137 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
LKAIADJA_06400 2.7e-206 fmhA 2.3.2.16, 2.3.2.17 V protein involved in methicillin resistance
LKAIADJA_06401 7.2e-47 K Transcriptional regulator PadR-like family
LKAIADJA_06402 4.1e-111 S ABC-2 family transporter protein
LKAIADJA_06403 3.5e-208 hmp 1.14.12.17 C Belongs to the globin family
LKAIADJA_06404 3.4e-136 spo0J K Belongs to the ParB family
LKAIADJA_06405 2.2e-204 metB 2.5.1.48, 4.4.1.8 E COG0626 Cystathionine beta-lyases cystathionine gamma-synthases
LKAIADJA_06406 9.7e-214 metC 2.5.1.48, 4.4.1.8 E cystathionine
LKAIADJA_06407 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 H Bifunctional homocysteine S-methyltransferase 5,10-methylenetetrahydrofolate reductase protein
LKAIADJA_06408 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LKAIADJA_06409 1.9e-138 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
LKAIADJA_06410 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LKAIADJA_06411 4.8e-73 K LytTr DNA-binding domain
LKAIADJA_06412 1.5e-56 S Protein of unknown function (DUF3021)
LKAIADJA_06413 3.1e-75 S Domain of unknown function (DUF4188)
LKAIADJA_06414 8.8e-215 fadA 2.3.1.16 I Belongs to the thiolase family
LKAIADJA_06415 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I Belongs to the enoyl-CoA hydratase isomerase family
LKAIADJA_06416 6e-227 1.3.8.6 I Acyl-CoA dehydrogenase, N-terminal domain
LKAIADJA_06417 2.8e-290 MA20_22985 6.2.1.3 IQ AMP-binding enzyme
LKAIADJA_06418 2.6e-294 2.8.3.1 I Belongs to the 3-oxoacid CoA-transferase family
LKAIADJA_06419 1.3e-52 yraB K helix_turn_helix, mercury resistance
LKAIADJA_06420 1.1e-45
LKAIADJA_06421 1.6e-137 IQ KR domain
LKAIADJA_06422 2.9e-18 S Protein of unknown function (DUF3021)
LKAIADJA_06423 4.7e-39 KT LytTr DNA-binding domain
LKAIADJA_06424 1.7e-241 P Major Facilitator Superfamily
LKAIADJA_06425 5e-140 supH S haloacid dehalogenase-like hydrolase
LKAIADJA_06426 9.4e-153 rhaS4 K helix_turn_helix, arabinose operon control protein
LKAIADJA_06427 9.1e-151 yicL EG of the drug metabolite transporter (DMT) superfamily
LKAIADJA_06428 1.4e-18 S LPXTG cell wall anchor motif
LKAIADJA_06429 3.7e-244 yfnA E Amino acid permease
LKAIADJA_06430 2.2e-79 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LKAIADJA_06431 3.5e-113 yobV1 K Transcriptional regulator
LKAIADJA_06432 2.7e-43
LKAIADJA_06433 1.5e-25 feoA P FeoA domain
LKAIADJA_06434 2.5e-310 feoB P transporter of a GTP-driven Fe(2 ) uptake system
LKAIADJA_06436 2.6e-51 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
LKAIADJA_06437 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LKAIADJA_06438 3.4e-233 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LKAIADJA_06439 4.5e-24 yqzJ
LKAIADJA_06440 1.9e-139 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LKAIADJA_06441 1.2e-137 yqjF S Uncharacterized conserved protein (COG2071)
LKAIADJA_06442 2.3e-35
LKAIADJA_06447 8e-98 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
LKAIADJA_06448 3.1e-122 yetF1 S membrane
LKAIADJA_06449 2.8e-07 S Protein of unknown function (DUF421)
LKAIADJA_06450 7.9e-70 S Protein of unknown function (DUF421)
LKAIADJA_06451 5.4e-286 clsA_1 I PLD-like domain
LKAIADJA_06452 2.1e-79 S Protein of unknown function (DUF421)
LKAIADJA_06453 9.3e-48 S SMI1-KNR4 cell-wall
LKAIADJA_06454 1.8e-206 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
LKAIADJA_06455 3.5e-42 S Putative amidase domain
LKAIADJA_06456 1.8e-59
LKAIADJA_06457 9.1e-42 DM E domain
LKAIADJA_06458 4.5e-36 qacC P Small Multidrug Resistance protein
LKAIADJA_06459 1.3e-179 L Replication protein
LKAIADJA_06460 3.9e-22
LKAIADJA_06461 1.7e-76
LKAIADJA_06462 1.8e-50 L Transposase and inactivated derivatives, TnpA family
LKAIADJA_06463 3.4e-08 K Cro/C1-type HTH DNA-binding domain
LKAIADJA_06464 1e-85 S Protein of unknwon function (DUF3310)
LKAIADJA_06465 7.4e-08 S PVL ORF-50-like family
LKAIADJA_06467 2.3e-40 S VRR_NUC
LKAIADJA_06468 0.0 S D5 N terminal like
LKAIADJA_06469 1.3e-77 S Protein of unknown function (DUF669)
LKAIADJA_06470 2.7e-08
LKAIADJA_06471 1.5e-162 res L helicase
LKAIADJA_06472 5.4e-119 S AAA domain
LKAIADJA_06473 2.8e-13 S Hypothetical protein of unknown function (DUF2483)
LKAIADJA_06474 4.1e-11 S Protein of unknown function (DUF1108)
LKAIADJA_06476 4.7e-07
LKAIADJA_06477 4.8e-14 S sequence-specific DNA binding
LKAIADJA_06478 2.7e-25 K sequence-specific DNA binding
LKAIADJA_06479 1e-47 E Pfam:DUF955
LKAIADJA_06480 0.0 bcgIA 2.1.1.72 V N-6 DNA Methylase
LKAIADJA_06481 6.7e-31 bcgIB 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
LKAIADJA_06482 1.1e-96 int L Arm DNA-binding domain
LKAIADJA_06483 3.6e-213 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
LKAIADJA_06484 2e-127 tcyN 3.6.3.21 E ABC-type polar amino acid transport system ATPase component
LKAIADJA_06485 2.3e-148 ET Bacterial periplasmic substrate-binding proteins
LKAIADJA_06486 1.2e-107 P ABC-type amino acid transport system permease component
LKAIADJA_06487 9.9e-105 P Binding-protein-dependent transport system inner membrane component
LKAIADJA_06488 1.5e-173 pfoR G Phosphotransferase system, EIIC
LKAIADJA_06489 1.3e-52 sarR K regulator
LKAIADJA_06490 5.7e-56
LKAIADJA_06491 5e-193 XK27_00915 C Luciferase-like monooxygenase
LKAIADJA_06492 1.1e-74 sceB S secretory antigen
LKAIADJA_06493 2e-08
LKAIADJA_06494 5.7e-245 nhaC C Na H antiporter
LKAIADJA_06495 3.1e-198 MA20_38170 1.5.1.28 C NAD NADP octopine nopaline dehydrogenase
LKAIADJA_06496 1.3e-55 S Domain of unknown function (DUF4870)
LKAIADJA_06497 4e-78 S COG3942 Surface antigen
LKAIADJA_06498 1.8e-45 sugE P Multidrug resistance protein
LKAIADJA_06499 8.9e-45 sugE P COG2076 Membrane transporters of cations and cationic drugs
LKAIADJA_06500 2.3e-173 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LKAIADJA_06501 5.1e-180 1.14.13.222 CH FAD binding domain
LKAIADJA_06502 4.4e-130 lytD 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LKAIADJA_06503 1.5e-11
LKAIADJA_06504 3e-73 S Protein of unknown function (DUF1641)
LKAIADJA_06505 0.0 fdhF 1.17.1.10, 1.17.1.9 C formate dehydrogenase
LKAIADJA_06506 1.4e-162 brpA K transcriptional
LKAIADJA_06507 3.3e-141 suhB 3.1.3.25 G Inositol monophosphatase
LKAIADJA_06508 2.6e-121 K Transcriptional regulator
LKAIADJA_06509 1.2e-84 S CAAX protease self-immunity
LKAIADJA_06510 3.4e-47
LKAIADJA_06511 2.9e-185 yleB 4.2.1.126 S Bacterial protein of unknown function (DUF871)
LKAIADJA_06512 1.2e-134 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LKAIADJA_06513 1.1e-254 sacX 2.7.1.211 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane
LKAIADJA_06514 4.8e-157 yleF K Helix-turn-helix domain, rpiR family
LKAIADJA_06515 1.1e-264 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
LKAIADJA_06516 3.1e-259 yifK E permease
LKAIADJA_06517 3.3e-139 fnt P Formate/nitrite transporter
LKAIADJA_06518 1.6e-21
LKAIADJA_06519 3.7e-19
LKAIADJA_06520 4.9e-22
LKAIADJA_06521 2.4e-113 3.1.3.23, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
LKAIADJA_06522 1.4e-143 yocS S transporter
LKAIADJA_06523 2.5e-92
LKAIADJA_06525 9.5e-297 glvC 2.7.1.199, 2.7.1.208 G PTS system
LKAIADJA_06526 1.7e-118 glvR K Transcriptional regulator
LKAIADJA_06527 3e-87 S Activator of Hsp90 ATPase homolog 1-like protein
LKAIADJA_06528 2e-220 mleN_2 C Na H antiporter
LKAIADJA_06529 1.3e-100 ywrF S Flavin reductase like domain
LKAIADJA_06530 3.7e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKAIADJA_06531 7.1e-206 hipO E amidohydrolase
LKAIADJA_06532 9.7e-182 P Sulfate permease
LKAIADJA_06534 6.4e-224 hutI 3.5.2.7 Q Belongs to the metallo-dependent hydrolases superfamily. HutI family
LKAIADJA_06535 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LKAIADJA_06536 7.8e-209 S Nucleoside recognition
LKAIADJA_06537 2.2e-162 K Transcriptional regulator
LKAIADJA_06538 1.6e-171 hutG 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
LKAIADJA_06539 1.7e-145 lyrA S CAAX protease self-immunity
LKAIADJA_06540 1.9e-116 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LKAIADJA_06541 7.8e-112 S MOSC domain
LKAIADJA_06542 1.9e-189 galM 5.1.3.3 G Aldose 1-epimerase
LKAIADJA_06543 8.7e-197 natB CP ABC-type Na efflux pump, permease component
LKAIADJA_06544 1.1e-153 yhaQ S ABC transporter, ATP-binding protein
LKAIADJA_06546 3.3e-90 Z012_06975 S Protein of unknown function (DUF805)
LKAIADJA_06547 7.2e-112 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
LKAIADJA_06548 3.8e-230 C Na H antiporter
LKAIADJA_06549 3e-129 S Putative adhesin
LKAIADJA_06550 8.2e-78 S Protein of unknown function (DUF1700)
LKAIADJA_06551 1.5e-52 K Transcriptional regulator, PadR family
LKAIADJA_06552 1.2e-190 gltS P Catalyzes the sodium-dependent transport of glutamate
LKAIADJA_06553 1.9e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LKAIADJA_06554 1.3e-160 corA P Mediates influx of magnesium ions
LKAIADJA_06555 8.1e-79 lcdH_1 S Thioesterase-like superfamily
LKAIADJA_06556 3.5e-54
LKAIADJA_06557 1.9e-164 3.1.1.83 I Steryl acetyl hydrolase
LKAIADJA_06558 3.2e-94
LKAIADJA_06559 7.2e-304 yhcA EGP Major facilitator Superfamily
LKAIADJA_06560 4.1e-105 emrA V COG1566 Multidrug resistance efflux pump
LKAIADJA_06561 3e-93 K Transcriptional regulator
LKAIADJA_06562 2.4e-191 tcaB EGP Major facilitator Superfamily
LKAIADJA_06563 9e-227 tcaA S response to antibiotic
LKAIADJA_06564 1.5e-69 tcaR K transcriptional
LKAIADJA_06565 2.4e-173 S DUF218 domain
LKAIADJA_06566 6.3e-117 hrtA 3.6.3.25 P ATP-binding protein
LKAIADJA_06567 4.2e-152 hrtB V Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
LKAIADJA_06568 3.2e-121 K Member of the two-component regulatory system HssS HssR involved in intracellular heme homeostasis and tempering of staphylococcal virulence. Phosphorylated HssR binds to a direct repeat sequence within hrtAB promoter and activates the expression of hrtAB, an efflux pump, in response to extracellular heme, hemin, hemoglobin or blood (By similarity)
LKAIADJA_06569 4.6e-239 hssS 2.7.13.3 T Member of the two-component regulatory system HssS HssR involved in intracellular heme homeostasis and tempering of staphylococcal virulence. HssS functions as a heme sensor histidine kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to an aspartate residue of HssR. HssR HssS activates the expression of hrtAB, an efflux pump, in response to extracellular heme, hemin, hemoglobin or blood (By similarity)
LKAIADJA_06570 9.8e-280 mqo 1.1.5.4 C malate quinone oxidoreductase
LKAIADJA_06571 1.4e-212 M Glycosyl transferases group 1
LKAIADJA_06572 2.1e-283 lctP C L-lactate permease
LKAIADJA_06573 0.0 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
LKAIADJA_06574 3e-49
LKAIADJA_06575 8.9e-95 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
LKAIADJA_06576 3.2e-186 yhfP 1.1.1.1 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
LKAIADJA_06577 2.3e-238 csbC EGP Major facilitator Superfamily
LKAIADJA_06578 7.2e-68 attT K Acetyltransferase (GNAT) domain
LKAIADJA_06579 4.4e-194 ycgT 1.18.1.2, 1.19.1.1 C reductase
LKAIADJA_06580 2.2e-67 S Protein of unknown function (DUF2871)
LKAIADJA_06581 1.1e-104 ycnI S Domain of unkown function (DUF1775)
LKAIADJA_06582 9.4e-44 copC P resistance protein CopC
LKAIADJA_06583 1.6e-153 S CopC domain
LKAIADJA_06584 1.2e-76 rpiB 5.3.1.34, 5.3.1.6 G Ribose/Galactose Isomerase
LKAIADJA_06585 1.5e-112 dhaL 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 S Dak2
LKAIADJA_06586 3.3e-170 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
LKAIADJA_06587 4.7e-207 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
LKAIADJA_06588 3.2e-133 K DeoR C terminal sensor domain
LKAIADJA_06589 2.3e-260 ycgA S C4-dicarboxylate anaerobic carrier
LKAIADJA_06590 2.8e-257 moxC C Luciferase-like monooxygenase
LKAIADJA_06591 7.9e-188 ytmO C Luciferase-like monooxygenase
LKAIADJA_06592 5.1e-301 nptA P Na+/Pi-cotransporter
LKAIADJA_06593 2.2e-168 corA P Transporter
LKAIADJA_06594 4.9e-110 M Ami_2
LKAIADJA_06595 5.1e-205 K Transcriptional regulator
LKAIADJA_06597 6.6e-30 S Domain of unknown function (DUF4889)
LKAIADJA_06598 2.6e-220 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LKAIADJA_06599 1.2e-58 S Protein of unknown function (DUF3139)
LKAIADJA_06600 1.9e-74 ohrR K transcriptional
LKAIADJA_06601 9.7e-51 hsp O Hsp20/alpha crystallin family
LKAIADJA_06602 6.5e-75 hsp O Belongs to the small heat shock protein (HSP20) family
LKAIADJA_06603 1.9e-100 ytmI K Acetyltransferase, gnat family
LKAIADJA_06604 1.5e-144 fnt P Formate/nitrite transporter
LKAIADJA_06605 4.8e-24
LKAIADJA_06606 3.6e-82 gstF 2.5.1.18 S Activator of Hsp90 ATPase homolog 1-like protein
LKAIADJA_06607 1.8e-104
LKAIADJA_06608 1.9e-92 S Belongs to the UPF0312 family
LKAIADJA_06609 5.6e-270 adcA P Belongs to the bacterial solute-binding protein 9 family
LKAIADJA_06610 8.9e-102 bdbD O Thioredoxin
LKAIADJA_06611 1.2e-61 S Domain of unknown function with cystatin-like fold (DUF4467)
LKAIADJA_06612 2.3e-51 nudA S ASCH
LKAIADJA_06613 2.9e-260 EGP Major facilitator Superfamily
LKAIADJA_06614 5.8e-09
LKAIADJA_06615 4e-127 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LKAIADJA_06616 6.5e-60 M LysM domain
LKAIADJA_06617 4.6e-152 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LKAIADJA_06618 6e-56 wxcN GT2 S GtrA-like protein
LKAIADJA_06619 2.6e-198 tcaB EGP Major facilitator Superfamily
LKAIADJA_06620 5e-52 K Integron-associated effector binding protein
LKAIADJA_06621 2.6e-117 S Peptidase_C39 like family
LKAIADJA_06622 5.4e-155 yjjH S Calcineurin-like phosphoesterase superfamily domain
LKAIADJA_06623 3.8e-145 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LKAIADJA_06624 2.1e-72 MA20_25245 K FR47-like protein
LKAIADJA_06625 1.9e-116 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LKAIADJA_06626 8.9e-162 S Protein of unknown function (DUF979)
LKAIADJA_06627 1.7e-120 S Protein of unknown function (DUF969)
LKAIADJA_06628 1.3e-62 S Protein of unknown function (DUF805)
LKAIADJA_06629 2.3e-303 rocB E Peptidase family M20/M25/M40
LKAIADJA_06630 7e-211 norB EGP of the major facilitator superfamily
LKAIADJA_06631 0.0 lytS 2.7.13.3 T Member of the two-component regulatory system LytR LytS that probably regulates genes involved in cell wall metabolism
LKAIADJA_06632 1.3e-139 lytT K Member of the two-component regulatory system LytR LytS that probably regulates genes involved in cell wall metabolism
LKAIADJA_06633 1.1e-53 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
LKAIADJA_06634 2.3e-117 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
LKAIADJA_06635 2e-91 srpF S Protein of unknown function (DUF4242)
LKAIADJA_06636 1.7e-139 ssuB P ATPases associated with a variety of cellular activities
LKAIADJA_06637 6.6e-176 ssuA P NMT1-like family
LKAIADJA_06638 1.5e-135 tauC P Binding-protein-dependent transport system inner membrane component
LKAIADJA_06639 2.6e-194 I acyl-CoA dehydrogenase
LKAIADJA_06640 5.3e-136 estA CE1 S Tributyrin esterase
LKAIADJA_06641 2.2e-112 opuCD P ABC transporter (permease)
LKAIADJA_06642 7.6e-177 opuCC M Amino acid ABC transporter amino acid-binding protein
LKAIADJA_06643 2.2e-103 opuCB P ABC transporter permease
LKAIADJA_06644 2.2e-218 opuCA 3.6.3.32 P Glycine betaine
LKAIADJA_06645 4.6e-82 lcdH_1 S Thioesterase-like superfamily
LKAIADJA_06646 3.7e-179 lcdH 1.1.1.108 I Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine
LKAIADJA_06647 9.4e-169 kce S beta-keto acid cleavage enzyme
LKAIADJA_06648 1.1e-95 betI9 K Bacterial regulatory proteins, tetR family
LKAIADJA_06649 6.2e-108 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
LKAIADJA_06650 2.7e-231 citN C Citrate transporter
LKAIADJA_06651 3.1e-191 EGP Major facilitator Superfamily
LKAIADJA_06652 1.1e-128 ybbM S YbbM seven transmembrane helix protein
LKAIADJA_06653 3.3e-115 ybbL S ABC transporter, ATP-binding protein
LKAIADJA_06654 1.4e-131 S CAAX protease self-immunity
LKAIADJA_06655 1.9e-297 yerD 1.4.7.1 E Belongs to the glutamate synthase family
LKAIADJA_06656 2.6e-94 O Thioredoxin
LKAIADJA_06657 3e-201 ysdC G M42 glutamyl aminopeptidase
LKAIADJA_06658 2.9e-148 IQ Short chain dehydrogenase
LKAIADJA_06659 4.2e-257 ydaH H transporter
LKAIADJA_06660 8.5e-287 ppx 3.6.1.11, 3.6.1.40 FP Exopolyphosphatase
LKAIADJA_06661 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LKAIADJA_06665 2e-08
LKAIADJA_06673 7.8e-08
LKAIADJA_06674 4.1e-78 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LKAIADJA_06675 2.6e-80 spoVAC S stage V sporulation protein AC
LKAIADJA_06676 7.1e-27 S Protein of unknown function (DUF1657)
LKAIADJA_06677 9.4e-161 cat P Catalase
LKAIADJA_06678 8.2e-32 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LKAIADJA_06679 1.5e-72 EG Spore germination protein
LKAIADJA_06680 1.5e-24 S Protein of unknown function (DUF2642)
LKAIADJA_06681 1.4e-45 L transposase activity
LKAIADJA_06682 8.1e-31 S Protein of unknown function (DUF2564)
LKAIADJA_06684 1e-41
LKAIADJA_06686 2.2e-207 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
LKAIADJA_06687 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
LKAIADJA_06688 3.7e-182 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
LKAIADJA_06689 4.7e-238 yurO G COG1653 ABC-type sugar transport system, periplasmic component
LKAIADJA_06690 1.1e-148 yurL 2.7.1.218 G pfkB family carbohydrate kinase
LKAIADJA_06691 7.3e-135 yurK K UTRA
LKAIADJA_06692 2.9e-204 msmX P Belongs to the ABC transporter superfamily
LKAIADJA_06693 7.7e-168 bsn L Ribonuclease
LKAIADJA_06694 2e-233 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
LKAIADJA_06695 8.7e-237 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
LKAIADJA_06696 5e-187 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LKAIADJA_06697 1.2e-109 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
LKAIADJA_06698 4.3e-147 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
LKAIADJA_06699 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
LKAIADJA_06700 4e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
LKAIADJA_06701 1e-54 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
LKAIADJA_06702 1.6e-277 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
LKAIADJA_06703 9.7e-113 pbuX F xanthine
LKAIADJA_06704 1.4e-96 pbuX F xanthine
LKAIADJA_06705 3.9e-235 pbuX F Permease family
LKAIADJA_06706 3.2e-300 pucR QT COG2508 Regulator of polyketide synthase expression
LKAIADJA_06707 7.3e-258 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
LKAIADJA_06708 6.7e-62 yunG
LKAIADJA_06709 7.3e-171 yunF S Protein of unknown function DUF72
LKAIADJA_06710 1.3e-140 yunE S membrane transporter protein
LKAIADJA_06711 5.1e-262 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
LKAIADJA_06712 1.1e-47 yunC S Domain of unknown function (DUF1805)
LKAIADJA_06713 3.2e-133 yunB S Sporulation protein YunB (Spo_YunB)
LKAIADJA_06714 1.3e-195 lytH M Peptidase, M23
LKAIADJA_06715 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LKAIADJA_06716 6.7e-66 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LKAIADJA_06717 1.1e-46 yutD S protein conserved in bacteria
LKAIADJA_06718 1e-75 yutE S Protein of unknown function DUF86
LKAIADJA_06719 3.2e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LKAIADJA_06720 5.6e-86 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
LKAIADJA_06721 8.5e-198 yutH S Spore coat protein
LKAIADJA_06722 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
LKAIADJA_06723 5.2e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LKAIADJA_06724 2.8e-171 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LKAIADJA_06725 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
LKAIADJA_06726 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
LKAIADJA_06727 1.1e-55 yuzD S protein conserved in bacteria
LKAIADJA_06728 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
LKAIADJA_06729 3.2e-39 yuzB S Belongs to the UPF0349 family
LKAIADJA_06730 1.7e-197 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LKAIADJA_06731 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LKAIADJA_06732 3.7e-63 erpA S Belongs to the HesB IscA family
LKAIADJA_06733 4.3e-49 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LKAIADJA_06734 6.1e-114 paiB K Putative FMN-binding domain
LKAIADJA_06735 1.8e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LKAIADJA_06737 1.7e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
LKAIADJA_06738 3.2e-236 yumB 1.6.99.3 C NADH dehydrogenase
LKAIADJA_06739 3.2e-26 yuiB S Putative membrane protein
LKAIADJA_06740 6.8e-116 yuiC S protein conserved in bacteria
LKAIADJA_06741 1.2e-77 yuiD S protein conserved in bacteria
LKAIADJA_06742 1e-279 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LKAIADJA_06743 8.1e-209 yuiF S antiporter
LKAIADJA_06744 7.4e-93 bioY S Biotin biosynthesis protein
LKAIADJA_06745 2.1e-119 yuiH S Oxidoreductase molybdopterin binding domain
LKAIADJA_06746 1.5e-166 besA S Putative esterase
LKAIADJA_06747 8.1e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LKAIADJA_06748 4.7e-224 entC 5.4.4.2 HQ Isochorismate synthase
LKAIADJA_06749 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
LKAIADJA_06750 9.3e-175 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
LKAIADJA_06751 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKAIADJA_06752 8.5e-36 mbtH S MbtH-like protein
LKAIADJA_06753 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
LKAIADJA_06754 8.8e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
LKAIADJA_06755 2.8e-227 yukF QT Transcriptional regulator
LKAIADJA_06756 2.8e-45 esxA S Belongs to the WXG100 family
LKAIADJA_06757 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
LKAIADJA_06758 5.2e-211 essB S WXG100 protein secretion system (Wss), protein YukC
LKAIADJA_06759 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
LKAIADJA_06760 0.0 esaA S type VII secretion protein EsaA
LKAIADJA_06761 6.6e-65 yueC S Family of unknown function (DUF5383)
LKAIADJA_06762 9.2e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKAIADJA_06763 1.1e-95 yueE S phosphohydrolase
LKAIADJA_06764 1.1e-23 S Protein of unknown function (DUF2642)
LKAIADJA_06765 5.2e-71 S Protein of unknown function (DUF2283)
LKAIADJA_06766 3.2e-190 yueF S transporter activity
LKAIADJA_06767 2.5e-30 yueG S Spore germination protein gerPA/gerPF
LKAIADJA_06768 7.4e-39 yueH S YueH-like protein
LKAIADJA_06769 1.8e-66 yueI S Protein of unknown function (DUF1694)
LKAIADJA_06770 1.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
LKAIADJA_06771 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LKAIADJA_06772 3.8e-229 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
LKAIADJA_06773 1.1e-22 yuzC
LKAIADJA_06775 3.1e-149 comQ H Polyprenyl synthetase
LKAIADJA_06777 0.0 comP 2.7.13.3 T Histidine kinase
LKAIADJA_06778 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LKAIADJA_06779 1.8e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
LKAIADJA_06780 3.3e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
LKAIADJA_06781 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LKAIADJA_06782 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LKAIADJA_06783 7.1e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LKAIADJA_06784 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LKAIADJA_06785 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LKAIADJA_06786 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
LKAIADJA_06787 3.2e-14
LKAIADJA_06788 3.7e-233 maeN C COG3493 Na citrate symporter
LKAIADJA_06789 1.1e-167 yufQ S Belongs to the binding-protein-dependent transport system permease family
LKAIADJA_06790 1.4e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
LKAIADJA_06791 1e-271 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
LKAIADJA_06792 1.2e-191 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
LKAIADJA_06793 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
LKAIADJA_06794 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
LKAIADJA_06795 6.3e-78 yufK S Family of unknown function (DUF5366)
LKAIADJA_06796 1.8e-74 yuxK S protein conserved in bacteria
LKAIADJA_06797 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
LKAIADJA_06798 4.2e-184 yuxJ EGP Major facilitator Superfamily
LKAIADJA_06800 4.2e-115 kapD L the KinA pathway to sporulation
LKAIADJA_06801 2.2e-69 kapB G Kinase associated protein B
LKAIADJA_06802 4.6e-233 T PhoQ Sensor
LKAIADJA_06803 1.9e-186 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
LKAIADJA_06804 1.3e-38 yugE S Domain of unknown function (DUF1871)
LKAIADJA_06805 1.4e-155 yugF I Hydrolase
LKAIADJA_06806 1.6e-85 alaR K Transcriptional regulator
LKAIADJA_06807 2.1e-199 yugH 2.6.1.1 E Aminotransferase
LKAIADJA_06808 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
LKAIADJA_06809 1.1e-34 yuzA S Domain of unknown function (DUF378)
LKAIADJA_06810 2e-227 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
LKAIADJA_06811 2.8e-229 yugK C Dehydrogenase
LKAIADJA_06812 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
LKAIADJA_06814 1.4e-71 yugN S YugN-like family
LKAIADJA_06815 3.1e-181 yugO P COG1226 Kef-type K transport systems
LKAIADJA_06816 1.2e-52 mstX S Membrane-integrating protein Mistic
LKAIADJA_06817 3.7e-36
LKAIADJA_06818 1.4e-116 yugP S Zn-dependent protease
LKAIADJA_06819 8.4e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
LKAIADJA_06820 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
LKAIADJA_06821 2.2e-72 yugU S Uncharacterised protein family UPF0047
LKAIADJA_06822 3.9e-35
LKAIADJA_06823 4.9e-131 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
LKAIADJA_06824 6e-169 mcpA NT chemotaxis protein
LKAIADJA_06825 6.1e-41 mcpA NT chemotaxis protein
LKAIADJA_06826 1.5e-113 mcpA NT chemotaxis protein
LKAIADJA_06827 9.1e-35 mcpA NT chemotaxis protein
LKAIADJA_06828 2.8e-41 mcpA NT chemotaxis protein
LKAIADJA_06829 5.5e-294 mcpA NT chemotaxis protein
LKAIADJA_06830 7.3e-238 mcpA NT chemotaxis protein
LKAIADJA_06832 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
LKAIADJA_06833 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
LKAIADJA_06834 1.6e-249 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
LKAIADJA_06835 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
LKAIADJA_06836 1.1e-252 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
LKAIADJA_06837 9.7e-183 ygjR S Oxidoreductase
LKAIADJA_06838 1.3e-194 yubA S transporter activity
LKAIADJA_06839 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
LKAIADJA_06841 1.3e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
LKAIADJA_06842 3.5e-272 yubD P Major Facilitator Superfamily
LKAIADJA_06843 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LKAIADJA_06844 1e-38 yiaA S yiaA/B two helix domain
LKAIADJA_06845 1.6e-236 ktrB P Potassium
LKAIADJA_06846 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)