ORF_ID e_value Gene_name EC_number CAZy COGs Description
CINOAHEC_00003 2e-81 L Phage integrase, N-terminal SAM-like domain
CINOAHEC_00004 4.8e-35 xkdA E IrrE N-terminal-like domain
CINOAHEC_00005 4.3e-13
CINOAHEC_00007 1.5e-18 K Cro/C1-type HTH DNA-binding domain
CINOAHEC_00008 4.9e-16 ropB K sequence-specific DNA binding
CINOAHEC_00009 3.9e-11 S Helix-turn-helix domain
CINOAHEC_00010 4.8e-43
CINOAHEC_00014 1e-170 D nuclear chromosome segregation
CINOAHEC_00015 1.2e-87 bet L RecT family
CINOAHEC_00016 4.1e-103 S Metallo-beta-lactamase superfamily
CINOAHEC_00018 3.1e-27 L primosome component and related proteins
CINOAHEC_00019 3.8e-07 S Loader and inhibitor of phage G40P
CINOAHEC_00020 1.3e-179 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
CINOAHEC_00023 3.5e-48 3.1.22.4
CINOAHEC_00024 1.3e-69
CINOAHEC_00028 3.2e-30
CINOAHEC_00031 1.1e-16 S Putative phage abortive infection protein
CINOAHEC_00032 2.2e-37
CINOAHEC_00033 1.7e-06 L PFAM Integrase catalytic
CINOAHEC_00038 5.2e-57 K DNA binding
CINOAHEC_00039 3e-126 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
CINOAHEC_00041 2.8e-30
CINOAHEC_00042 1.4e-73
CINOAHEC_00043 1.1e-71
CINOAHEC_00044 1.9e-234 S phage terminase, large subunit
CINOAHEC_00045 1.2e-251 yqbA S portal protein
CINOAHEC_00046 1.8e-146 S Phage Mu protein F like protein
CINOAHEC_00048 9.8e-97 yqbD 2.1.1.72 L Putative phage serine protease XkdF
CINOAHEC_00049 9.6e-148 xkdG S Phage capsid family
CINOAHEC_00050 3.9e-25 S YqbF, hypothetical protein domain
CINOAHEC_00051 2e-46 S Protein of unknown function (DUF3199)
CINOAHEC_00052 8.8e-57 yqbH S Domain of unknown function (DUF3599)
CINOAHEC_00053 1.6e-85 S Bacteriophage HK97-gp10, putative tail-component
CINOAHEC_00054 4.6e-76
CINOAHEC_00055 2.7e-25
CINOAHEC_00056 3.3e-245 xkdK S Phage tail sheath C-terminal domain
CINOAHEC_00057 7.4e-74 xkdM S Phage tail tube protein
CINOAHEC_00058 2.6e-66 S Phage XkdN-like tail assembly chaperone protein, TAC
CINOAHEC_00059 0.0 xkdO L Transglycosylase SLT domain
CINOAHEC_00060 6e-110 xkdP S Lysin motif
CINOAHEC_00061 6.1e-177 yqbQ 3.2.1.96 G NLP P60 protein
CINOAHEC_00062 7.2e-32 xkdR S Protein of unknown function (DUF2577)
CINOAHEC_00063 7.6e-68 xkdS S Protein of unknown function (DUF2634)
CINOAHEC_00064 7.4e-181 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
CINOAHEC_00065 6.2e-97 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
CINOAHEC_00066 2.5e-35
CINOAHEC_00067 2.8e-172
CINOAHEC_00068 1.1e-45 xkdW S XkdW protein
CINOAHEC_00069 4.6e-21
CINOAHEC_00070 1.1e-148 xepA
CINOAHEC_00071 2.8e-34 xhlA S Haemolysin XhlA
CINOAHEC_00072 2.7e-31 xhlB S SPP1 phage holin
CINOAHEC_00073 1.5e-122 xlyB 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
CINOAHEC_00074 5.6e-56 S SMI1-KNR4 cell-wall
CINOAHEC_00075 7.8e-276 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
CINOAHEC_00076 3.2e-190 S Histidine kinase
CINOAHEC_00078 3.1e-13
CINOAHEC_00079 1.5e-09 K Transcriptional regulator
CINOAHEC_00080 5.1e-10 lexA 3.4.21.88 KT domain protein
CINOAHEC_00081 2e-08
CINOAHEC_00083 9.6e-88 S Thymidylate synthase
CINOAHEC_00084 5.4e-31 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CINOAHEC_00086 7e-36
CINOAHEC_00089 1.3e-23 sspB S spore protein
CINOAHEC_00099 4.1e-10 K Cro/C1-type HTH DNA-binding domain
CINOAHEC_00100 1.1e-93 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
CINOAHEC_00102 5.3e-245 cisA2 L Recombinase
CINOAHEC_00103 8.7e-69 spoVK O stage V sporulation protein K
CINOAHEC_00104 6.1e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CINOAHEC_00105 1.7e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
CINOAHEC_00106 1.1e-68 glnR K transcriptional
CINOAHEC_00107 7e-261 glnA 6.3.1.2 E glutamine synthetase
CINOAHEC_00108 3.8e-10
CINOAHEC_00109 6.6e-31
CINOAHEC_00110 2.5e-69 Q Collagen triple helix repeat (20 copies)
CINOAHEC_00111 5.7e-94 M Glycosyltransferase like family
CINOAHEC_00112 3.4e-121 H Methionine biosynthesis protein MetW
CINOAHEC_00113 1.4e-193 M COG0463 Glycosyltransferases involved in cell wall biogenesis
CINOAHEC_00114 4.9e-217 sumf2 2.1.1.295 GT2,GT4 H N-terminal domain of galactosyltransferase
CINOAHEC_00116 2e-97 ynaD J Acetyltransferase (GNAT) domain
CINOAHEC_00117 6.1e-75 S CAAX protease self-immunity
CINOAHEC_00118 4.7e-08 S Uncharacterised protein family (UPF0715)
CINOAHEC_00119 5.2e-09 yoaW
CINOAHEC_00120 1.5e-22 K Cro/C1-type HTH DNA-binding domain
CINOAHEC_00121 1.7e-111 ynaE S Domain of unknown function (DUF3885)
CINOAHEC_00124 3.2e-75 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
CINOAHEC_00125 1.6e-38 yhbS S family acetyltransferase
CINOAHEC_00126 3.9e-254 xynT G MFS/sugar transport protein
CINOAHEC_00127 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
CINOAHEC_00128 3.1e-212 xylR GK ROK family
CINOAHEC_00129 3.2e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
CINOAHEC_00130 3.3e-291 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
CINOAHEC_00131 1.1e-110 yokF 3.1.31.1 L RNA catabolic process
CINOAHEC_00132 1.8e-254 iolT EGP Major facilitator Superfamily
CINOAHEC_00133 1e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CINOAHEC_00134 2.4e-83 yncE S Protein of unknown function (DUF2691)
CINOAHEC_00135 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
CINOAHEC_00136 5.2e-15
CINOAHEC_00142 1.6e-89
CINOAHEC_00143 8.4e-73 K BRO family, N-terminal domain
CINOAHEC_00144 2e-33
CINOAHEC_00145 8.4e-13 K Helix-turn-helix domain
CINOAHEC_00146 1.1e-16 xre K Helix-turn-helix XRE-family like proteins
CINOAHEC_00148 1.1e-47
CINOAHEC_00149 1.8e-27 S Protein of unknown function (DUF4064)
CINOAHEC_00150 4.7e-48 xkdA E IrrE N-terminal-like domain
CINOAHEC_00151 2.8e-144 L Belongs to the 'phage' integrase family
CINOAHEC_00152 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
CINOAHEC_00153 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CINOAHEC_00154 7.9e-129 ydiL S CAAX protease self-immunity
CINOAHEC_00155 2.9e-27 ydiK S Domain of unknown function (DUF4305)
CINOAHEC_00156 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CINOAHEC_00157 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
CINOAHEC_00158 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CINOAHEC_00159 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
CINOAHEC_00160 0.0 ydiF S ABC transporter
CINOAHEC_00161 3.9e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CINOAHEC_00162 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
CINOAHEC_00163 2.9e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
CINOAHEC_00164 2.6e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
CINOAHEC_00165 6e-177 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CINOAHEC_00167 8.2e-36 bofA S Sigma-K factor-processing regulatory protein BofA
CINOAHEC_00168 7.9e-32 yaaL S Protein of unknown function (DUF2508)
CINOAHEC_00169 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CINOAHEC_00170 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CINOAHEC_00171 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CINOAHEC_00172 3.3e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
CINOAHEC_00173 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
CINOAHEC_00174 1.4e-213 yaaH M Glycoside Hydrolase Family
CINOAHEC_00175 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
CINOAHEC_00176 6.3e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
CINOAHEC_00177 1.3e-09
CINOAHEC_00178 1.2e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CINOAHEC_00179 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CINOAHEC_00180 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CINOAHEC_00181 9.8e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
CINOAHEC_00182 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
CINOAHEC_00183 1e-181 yaaC S YaaC-like Protein
CINOAHEC_00184 1.8e-92 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CINOAHEC_00185 1.3e-240 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CINOAHEC_00189 4.9e-163 yqaJ L YqaJ-like viral recombinase domain
CINOAHEC_00191 3.4e-39 S COG NOG14552 non supervised orthologous group
CINOAHEC_00196 1.3e-89 thiT S Thiamine transporter protein (Thia_YuaJ)
CINOAHEC_00197 2.4e-92 M1-753 M FR47-like protein
CINOAHEC_00198 4.5e-187 yuaG 3.4.21.72 S protein conserved in bacteria
CINOAHEC_00199 1.2e-75 yuaF OU Membrane protein implicated in regulation of membrane protease activity
CINOAHEC_00200 8.7e-84 yuaE S DinB superfamily
CINOAHEC_00201 5.6e-106 yuaD
CINOAHEC_00202 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
CINOAHEC_00203 4e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
CINOAHEC_00204 3.6e-94 yuaC K Belongs to the GbsR family
CINOAHEC_00205 2.2e-91 yuaB
CINOAHEC_00206 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
CINOAHEC_00207 5.6e-234 ktrB P Potassium
CINOAHEC_00208 1e-38 yiaA S yiaA/B two helix domain
CINOAHEC_00209 7.9e-151 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CINOAHEC_00210 1.7e-274 yubD P Major Facilitator Superfamily
CINOAHEC_00211 1.3e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
CINOAHEC_00213 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
CINOAHEC_00214 3.1e-196 yubA S transporter activity
CINOAHEC_00215 3.3e-183 ygjR S Oxidoreductase
CINOAHEC_00216 6.7e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
CINOAHEC_00217 7.2e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
CINOAHEC_00218 1.4e-275 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
CINOAHEC_00219 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
CINOAHEC_00220 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
CINOAHEC_00221 7.3e-238 mcpA NT chemotaxis protein
CINOAHEC_00222 8.5e-295 mcpA NT chemotaxis protein
CINOAHEC_00223 6.9e-220 mcpA NT chemotaxis protein
CINOAHEC_00224 3.2e-225 mcpA NT chemotaxis protein
CINOAHEC_00225 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
CINOAHEC_00226 2.3e-35
CINOAHEC_00227 2.1e-72 yugU S Uncharacterised protein family UPF0047
CINOAHEC_00228 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
CINOAHEC_00229 8.4e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
CINOAHEC_00230 1.4e-116 yugP S Zn-dependent protease
CINOAHEC_00231 2.3e-38
CINOAHEC_00232 1.1e-53 mstX S Membrane-integrating protein Mistic
CINOAHEC_00233 2.2e-182 yugO P COG1226 Kef-type K transport systems
CINOAHEC_00234 1.4e-71 yugN S YugN-like family
CINOAHEC_00236 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
CINOAHEC_00237 2.6e-227 yugK C Dehydrogenase
CINOAHEC_00238 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
CINOAHEC_00239 1.1e-34 yuzA S Domain of unknown function (DUF378)
CINOAHEC_00240 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
CINOAHEC_00241 2.1e-199 yugH 2.6.1.1 E Aminotransferase
CINOAHEC_00242 1.6e-85 alaR K Transcriptional regulator
CINOAHEC_00243 2.5e-155 yugF I Hydrolase
CINOAHEC_00244 4.6e-39 yugE S Domain of unknown function (DUF1871)
CINOAHEC_00245 4.9e-226 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
CINOAHEC_00246 1.3e-232 T PhoQ Sensor
CINOAHEC_00247 7.4e-70 kapB G Kinase associated protein B
CINOAHEC_00248 4.2e-115 kapD L the KinA pathway to sporulation
CINOAHEC_00250 1.9e-184 yuxJ EGP Major facilitator Superfamily
CINOAHEC_00251 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
CINOAHEC_00252 6.3e-75 yuxK S protein conserved in bacteria
CINOAHEC_00253 6.3e-78 yufK S Family of unknown function (DUF5366)
CINOAHEC_00254 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
CINOAHEC_00255 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
CINOAHEC_00256 2.5e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
CINOAHEC_00257 7.8e-272 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
CINOAHEC_00258 1.4e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
CINOAHEC_00259 8.6e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
CINOAHEC_00260 6.3e-233 maeN C COG3493 Na citrate symporter
CINOAHEC_00261 5e-15
CINOAHEC_00262 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
CINOAHEC_00263 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CINOAHEC_00264 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CINOAHEC_00265 3.5e-261 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CINOAHEC_00266 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CINOAHEC_00267 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CINOAHEC_00268 5.7e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
CINOAHEC_00269 5.1e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
CINOAHEC_00270 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CINOAHEC_00271 0.0 comP 2.7.13.3 T Histidine kinase
CINOAHEC_00273 3.5e-137 comQ H Belongs to the FPP GGPP synthase family
CINOAHEC_00275 1.1e-22 yuzC
CINOAHEC_00276 3.1e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
CINOAHEC_00277 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CINOAHEC_00278 9.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
CINOAHEC_00279 3e-66 yueI S Protein of unknown function (DUF1694)
CINOAHEC_00280 7.4e-39 yueH S YueH-like protein
CINOAHEC_00281 6.6e-31 yueG S Spore germination protein gerPA/gerPF
CINOAHEC_00282 3.2e-190 yueF S transporter activity
CINOAHEC_00283 2e-70 S Protein of unknown function (DUF2283)
CINOAHEC_00284 2.9e-24 S Protein of unknown function (DUF2642)
CINOAHEC_00285 4.8e-96 yueE S phosphohydrolase
CINOAHEC_00286 7.1e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CINOAHEC_00287 3.3e-64 yueC S Family of unknown function (DUF5383)
CINOAHEC_00288 0.0 esaA S type VII secretion protein EsaA
CINOAHEC_00289 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
CINOAHEC_00290 2.3e-211 essB S WXG100 protein secretion system (Wss), protein YukC
CINOAHEC_00291 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
CINOAHEC_00292 2.8e-45 esxA S Belongs to the WXG100 family
CINOAHEC_00293 1.5e-228 yukF QT Transcriptional regulator
CINOAHEC_00294 1.8e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
CINOAHEC_00295 9.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
CINOAHEC_00296 2.5e-35 mbtH S MbtH-like protein
CINOAHEC_00297 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CINOAHEC_00298 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
CINOAHEC_00299 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
CINOAHEC_00300 1.5e-225 entC 5.4.4.2 HQ Isochorismate synthase
CINOAHEC_00301 3.6e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CINOAHEC_00302 3.9e-167 besA S Putative esterase
CINOAHEC_00303 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
CINOAHEC_00304 4.4e-93 bioY S Biotin biosynthesis protein
CINOAHEC_00305 3.9e-211 yuiF S antiporter
CINOAHEC_00306 3.4e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CINOAHEC_00307 2e-77 yuiD S protein conserved in bacteria
CINOAHEC_00308 1.4e-116 yuiC S protein conserved in bacteria
CINOAHEC_00309 1.2e-25 yuiB S Putative membrane protein
CINOAHEC_00310 1.2e-235 yumB 1.6.99.3 C NADH dehydrogenase
CINOAHEC_00311 1.7e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
CINOAHEC_00313 7.9e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CINOAHEC_00314 7.2e-115 paiB K Putative FMN-binding domain
CINOAHEC_00315 1.8e-71 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CINOAHEC_00316 3.7e-63 erpA S Belongs to the HesB IscA family
CINOAHEC_00317 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CINOAHEC_00318 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CINOAHEC_00319 3.2e-39 yuzB S Belongs to the UPF0349 family
CINOAHEC_00320 2.7e-199 yutJ 1.6.99.3 C NADH dehydrogenase
CINOAHEC_00321 8.7e-56 yuzD S protein conserved in bacteria
CINOAHEC_00322 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
CINOAHEC_00323 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
CINOAHEC_00324 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
CINOAHEC_00325 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CINOAHEC_00326 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
CINOAHEC_00327 1e-198 yutH S Spore coat protein
CINOAHEC_00328 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
CINOAHEC_00329 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
CINOAHEC_00330 1e-75 yutE S Protein of unknown function DUF86
CINOAHEC_00331 9.7e-48 yutD S protein conserved in bacteria
CINOAHEC_00332 1.8e-110 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
CINOAHEC_00333 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CINOAHEC_00334 1.3e-195 lytH M Peptidase, M23
CINOAHEC_00335 3.9e-131 yunB S Sporulation protein YunB (Spo_YunB)
CINOAHEC_00336 5.3e-47 yunC S Domain of unknown function (DUF1805)
CINOAHEC_00337 3.9e-262 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
CINOAHEC_00338 4.5e-141 yunE S membrane transporter protein
CINOAHEC_00339 4.3e-171 yunF S Protein of unknown function DUF72
CINOAHEC_00340 2.8e-60 yunG
CINOAHEC_00341 4.3e-258 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
CINOAHEC_00342 8.3e-301 pucR QT COG2508 Regulator of polyketide synthase expression
CINOAHEC_00343 1e-230 pbuX F Permease family
CINOAHEC_00344 1.6e-222 pbuX F xanthine
CINOAHEC_00345 2.4e-278 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
CINOAHEC_00346 1.7e-54 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
CINOAHEC_00348 1.8e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
CINOAHEC_00349 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
CINOAHEC_00350 3.7e-151 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
CINOAHEC_00351 3.1e-110 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
CINOAHEC_00352 2.1e-185 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CINOAHEC_00354 1e-237 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
CINOAHEC_00355 1.4e-234 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
CINOAHEC_00356 2.4e-169 bsn L Ribonuclease
CINOAHEC_00357 1.2e-205 msmX P Belongs to the ABC transporter superfamily
CINOAHEC_00358 1.1e-135 yurK K UTRA
CINOAHEC_00359 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
CINOAHEC_00360 8.1e-168 yurM P COG0395 ABC-type sugar transport system, permease component
CINOAHEC_00361 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
CINOAHEC_00362 1.2e-238 yurO G COG1653 ABC-type sugar transport system, periplasmic component
CINOAHEC_00363 2.6e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
CINOAHEC_00364 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
CINOAHEC_00365 3.2e-206 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
CINOAHEC_00367 1e-41
CINOAHEC_00368 8.3e-28
CINOAHEC_00372 4e-108 S aspartate phosphatase
CINOAHEC_00373 3e-283 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
CINOAHEC_00374 2.4e-83 S SMI1-KNR4 cell-wall
CINOAHEC_00375 1.5e-127 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
CINOAHEC_00376 7.1e-58 S Bacteriophage holin family
CINOAHEC_00377 5.9e-96 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
CINOAHEC_00379 1.3e-12
CINOAHEC_00380 3.1e-84
CINOAHEC_00381 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
CINOAHEC_00382 1.5e-107 mur1 NU Prophage endopeptidase tail
CINOAHEC_00383 2.6e-43 S Phage tail protein
CINOAHEC_00384 6.6e-151 D Phage-related minor tail protein
CINOAHEC_00386 6e-53 S phage major tail protein, phi13 family
CINOAHEC_00387 2.2e-18
CINOAHEC_00388 1.9e-15 S Bacteriophage HK97-gp10, putative tail-component
CINOAHEC_00389 1.2e-07 S head-tail adaptor
CINOAHEC_00390 1e-10 S Phage gp6-like head-tail connector protein
CINOAHEC_00391 5e-64 S Phage capsid family
CINOAHEC_00392 5.5e-48 S Caudovirus prohead serine protease
CINOAHEC_00393 4.3e-105 S Phage portal protein
CINOAHEC_00394 1.3e-150 S Phage Terminase
CINOAHEC_00395 4.5e-17
CINOAHEC_00396 5.1e-28 L HNH endonuclease
CINOAHEC_00399 3.2e-141
CINOAHEC_00400 1.3e-21
CINOAHEC_00401 9.7e-170 dnaB 3.6.4.12 L replicative DNA helicase
CINOAHEC_00402 5.1e-25 S Loader and inhibitor of phage G40P
CINOAHEC_00403 4.4e-82 L DnaD domain protein
CINOAHEC_00405 4.8e-13
CINOAHEC_00406 6e-88 S Phage regulatory protein Rha (Phage_pRha)
CINOAHEC_00407 1.1e-60 S Hypothetical protein (DUF2513)
CINOAHEC_00408 8.7e-23
CINOAHEC_00411 3.6e-23
CINOAHEC_00413 3.1e-25 K Helix-turn-helix XRE-family like proteins
CINOAHEC_00414 1.6e-42 E Zn peptidase
CINOAHEC_00415 1.5e-150 S Pfam:Arm-DNA-bind_4
CINOAHEC_00416 3.5e-271 sufB O FeS cluster assembly
CINOAHEC_00417 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
CINOAHEC_00418 3.6e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CINOAHEC_00419 4.5e-244 sufD O assembly protein SufD
CINOAHEC_00420 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
CINOAHEC_00421 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CINOAHEC_00422 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
CINOAHEC_00423 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
CINOAHEC_00424 2.4e-184 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CINOAHEC_00425 2.4e-56 yusD S SCP-2 sterol transfer family
CINOAHEC_00426 5.6e-55 traF CO Thioredoxin
CINOAHEC_00427 1.3e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
CINOAHEC_00428 1.1e-39 yusG S Protein of unknown function (DUF2553)
CINOAHEC_00429 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
CINOAHEC_00430 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
CINOAHEC_00431 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
CINOAHEC_00432 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
CINOAHEC_00433 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
CINOAHEC_00434 8.1e-09 S YuzL-like protein
CINOAHEC_00435 7.1e-164 fadM E Proline dehydrogenase
CINOAHEC_00436 5.1e-40
CINOAHEC_00437 5.4e-53 yusN M Coat F domain
CINOAHEC_00438 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
CINOAHEC_00439 3.2e-292 yusP P Major facilitator superfamily
CINOAHEC_00440 2.7e-64 yusQ S Tautomerase enzyme
CINOAHEC_00441 1.3e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CINOAHEC_00442 5.7e-158 yusT K LysR substrate binding domain
CINOAHEC_00443 3.8e-47 yusU S Protein of unknown function (DUF2573)
CINOAHEC_00444 1e-153 yusV 3.6.3.34 HP ABC transporter
CINOAHEC_00445 2.5e-66 S YusW-like protein
CINOAHEC_00446 1.1e-301 pepF2 E COG1164 Oligoendopeptidase F
CINOAHEC_00447 1.2e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CINOAHEC_00448 4.7e-79 dps P Ferritin-like domain
CINOAHEC_00449 1.6e-236 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CINOAHEC_00450 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CINOAHEC_00451 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
CINOAHEC_00452 1.3e-157 yuxN K Transcriptional regulator
CINOAHEC_00453 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
CINOAHEC_00454 1.1e-23 S Protein of unknown function (DUF3970)
CINOAHEC_00455 3.7e-247 gerAA EG Spore germination protein
CINOAHEC_00456 9.1e-198 gerAB E Spore germination protein
CINOAHEC_00457 6e-189 gerAC S Spore germination B3/ GerAC like, C-terminal
CINOAHEC_00458 1.3e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CINOAHEC_00459 5.5e-187 vraS 2.7.13.3 T Histidine kinase
CINOAHEC_00460 4.7e-126 yvqF S Cell wall-active antibiotics response 4TMS YvqF
CINOAHEC_00461 4.8e-125 liaG S Putative adhesin
CINOAHEC_00462 3.6e-104 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
CINOAHEC_00463 5.6e-62 liaI S membrane
CINOAHEC_00464 1.4e-226 yvqJ EGP Major facilitator Superfamily
CINOAHEC_00465 2.7e-100 yvqK 2.5.1.17 S Adenosyltransferase
CINOAHEC_00466 4.7e-241 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
CINOAHEC_00467 1.9e-184 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CINOAHEC_00468 1.3e-168 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
CINOAHEC_00469 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CINOAHEC_00470 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
CINOAHEC_00471 0.0 T PhoQ Sensor
CINOAHEC_00472 3.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CINOAHEC_00473 3.6e-22
CINOAHEC_00474 1.6e-97 yvrI K RNA polymerase
CINOAHEC_00475 2.4e-19 S YvrJ protein family
CINOAHEC_00476 3.1e-228 oxdC 4.1.1.2 G Oxalate decarboxylase
CINOAHEC_00477 1.1e-63 yvrL S Regulatory protein YrvL
CINOAHEC_00478 4.1e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
CINOAHEC_00479 1.6e-123 macB V ABC transporter, ATP-binding protein
CINOAHEC_00480 7.6e-174 M Efflux transporter rnd family, mfp subunit
CINOAHEC_00481 4.9e-148 fhuC 3.6.3.34 HP ABC transporter
CINOAHEC_00482 6.9e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CINOAHEC_00483 7.9e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CINOAHEC_00484 1.2e-177 fhuD P ABC transporter
CINOAHEC_00485 4.9e-236 yvsH E Arginine ornithine antiporter
CINOAHEC_00486 6.5e-16 S Small spore protein J (Spore_SspJ)
CINOAHEC_00487 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
CINOAHEC_00488 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
CINOAHEC_00489 9.2e-167 yvgK P COG1910 Periplasmic molybdate-binding protein domain
CINOAHEC_00490 1.6e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
CINOAHEC_00491 6.9e-119 modB P COG4149 ABC-type molybdate transport system, permease component
CINOAHEC_00492 1.1e-155 yvgN S reductase
CINOAHEC_00493 5.4e-86 yvgO
CINOAHEC_00494 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
CINOAHEC_00495 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
CINOAHEC_00496 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CINOAHEC_00497 0.0 helD 3.6.4.12 L DNA helicase
CINOAHEC_00498 4.1e-107 yvgT S membrane
CINOAHEC_00499 8.5e-72 bdbC O Required for disulfide bond formation in some proteins
CINOAHEC_00500 1.6e-104 bdbD O Thioredoxin
CINOAHEC_00501 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
CINOAHEC_00502 0.0 copA 3.6.3.54 P P-type ATPase
CINOAHEC_00503 5.9e-29 copZ P Copper resistance protein CopZ
CINOAHEC_00504 2.2e-48 csoR S transcriptional
CINOAHEC_00505 3.1e-195 yvaA 1.1.1.371 S Oxidoreductase
CINOAHEC_00506 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CINOAHEC_00507 0.0 yvaC S Fusaric acid resistance protein-like
CINOAHEC_00508 5.7e-73 yvaD S Family of unknown function (DUF5360)
CINOAHEC_00509 6.3e-55 yvaE P Small Multidrug Resistance protein
CINOAHEC_00510 8.7e-96 K Bacterial regulatory proteins, tetR family
CINOAHEC_00511 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CINOAHEC_00513 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CINOAHEC_00514 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
CINOAHEC_00515 5.6e-143 est 3.1.1.1 S Carboxylesterase
CINOAHEC_00516 2.4e-23 secG U Preprotein translocase subunit SecG
CINOAHEC_00517 3.8e-150 yvaM S Serine aminopeptidase, S33
CINOAHEC_00518 7.5e-36 yvzC K Transcriptional
CINOAHEC_00519 4e-69 K transcriptional
CINOAHEC_00520 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
CINOAHEC_00521 2.2e-54 yodB K transcriptional
CINOAHEC_00522 1.9e-218 NT chemotaxis protein
CINOAHEC_00523 1.5e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
CINOAHEC_00524 4.8e-168 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
CINOAHEC_00525 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
CINOAHEC_00526 9.2e-209 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
CINOAHEC_00527 3.3e-60 yvbF K Belongs to the GbsR family
CINOAHEC_00528 1.9e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
CINOAHEC_00529 3.6e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
CINOAHEC_00530 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
CINOAHEC_00531 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
CINOAHEC_00532 3.5e-97 yvbF K Belongs to the GbsR family
CINOAHEC_00533 2.4e-102 yvbG U UPF0056 membrane protein
CINOAHEC_00534 1.9e-112 yvbH S YvbH-like oligomerisation region
CINOAHEC_00535 1e-122 exoY M Membrane
CINOAHEC_00536 0.0 tcaA S response to antibiotic
CINOAHEC_00537 3.8e-81 yvbK 3.1.3.25 K acetyltransferase
CINOAHEC_00538 2.7e-174 EGP Major facilitator Superfamily
CINOAHEC_00539 3.7e-152
CINOAHEC_00540 2.3e-114 S GlcNAc-PI de-N-acetylase
CINOAHEC_00541 1.4e-122 C WbqC-like protein family
CINOAHEC_00542 7.6e-114 M Protein involved in cellulose biosynthesis
CINOAHEC_00543 1.1e-156 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CINOAHEC_00544 9.6e-148 5.1.3.2 M GDP-mannose 4,6 dehydratase
CINOAHEC_00545 1.6e-184 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
CINOAHEC_00546 2.8e-217 1.1.1.136 M UDP binding domain
CINOAHEC_00547 1.1e-165 ywaD 3.4.11.10, 3.4.11.6 S PA domain
CINOAHEC_00548 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CINOAHEC_00549 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
CINOAHEC_00550 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CINOAHEC_00551 6.5e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
CINOAHEC_00552 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CINOAHEC_00553 1.8e-184 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
CINOAHEC_00554 1.6e-252 araE EGP Major facilitator Superfamily
CINOAHEC_00555 5.5e-203 araR K transcriptional
CINOAHEC_00556 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CINOAHEC_00557 5.1e-159 yvbU K Transcriptional regulator
CINOAHEC_00558 1.2e-155 yvbV EG EamA-like transporter family
CINOAHEC_00559 3.7e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
CINOAHEC_00560 4.4e-194 yvbX S Glycosyl hydrolase
CINOAHEC_00561 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
CINOAHEC_00562 1.2e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
CINOAHEC_00563 1.5e-137 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
CINOAHEC_00564 2.6e-106 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CINOAHEC_00565 1.9e-198 desK 2.7.13.3 T Histidine kinase
CINOAHEC_00566 7.6e-132 yvfS V COG0842 ABC-type multidrug transport system, permease component
CINOAHEC_00567 6.6e-162 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
CINOAHEC_00568 2.9e-156 rsbQ S Alpha/beta hydrolase family
CINOAHEC_00569 1.2e-198 rsbU 3.1.3.3 T response regulator
CINOAHEC_00570 1.7e-248 galA 3.2.1.89 G arabinogalactan
CINOAHEC_00571 0.0 lacA 3.2.1.23 G beta-galactosidase
CINOAHEC_00572 7.2e-150 ganQ P transport
CINOAHEC_00573 1.1e-231 malC P COG1175 ABC-type sugar transport systems, permease components
CINOAHEC_00574 2.9e-232 cycB G COG2182 Maltose-binding periplasmic proteins domains
CINOAHEC_00575 1.8e-184 lacR K Transcriptional regulator
CINOAHEC_00576 2.7e-113 yvfI K COG2186 Transcriptional regulators
CINOAHEC_00577 2.6e-308 yvfH C L-lactate permease
CINOAHEC_00578 4.4e-239 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
CINOAHEC_00579 1e-31 yvfG S YvfG protein
CINOAHEC_00580 2.9e-187 yvfF GM Exopolysaccharide biosynthesis protein
CINOAHEC_00581 1.5e-219 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
CINOAHEC_00582 6.6e-55 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
CINOAHEC_00583 2.6e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
CINOAHEC_00584 2.8e-258 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CINOAHEC_00585 3.3e-189 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
CINOAHEC_00586 4.4e-205 epsI GM pyruvyl transferase
CINOAHEC_00587 5.8e-194 epsH GT2 S Glycosyltransferase like family 2
CINOAHEC_00588 1.1e-206 epsG S EpsG family
CINOAHEC_00589 1.9e-217 epsF GT4 M Glycosyl transferases group 1
CINOAHEC_00590 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
CINOAHEC_00591 2e-224 epsD GT4 M Glycosyl transferase 4-like
CINOAHEC_00592 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
CINOAHEC_00593 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
CINOAHEC_00594 4e-122 ywqC M biosynthesis protein
CINOAHEC_00595 6.3e-76 slr K transcriptional
CINOAHEC_00596 1.8e-281 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
CINOAHEC_00598 4.6e-93 padC Q Phenolic acid decarboxylase
CINOAHEC_00599 2.1e-71 MA20_18690 S Protein of unknown function (DUF3237)
CINOAHEC_00600 2.8e-102 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
CINOAHEC_00601 3.5e-260 pbpE V Beta-lactamase
CINOAHEC_00602 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
CINOAHEC_00603 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
CINOAHEC_00604 1.8e-295 yveA E amino acid
CINOAHEC_00605 2.6e-106 yvdT K Transcriptional regulator
CINOAHEC_00606 7.4e-50 ykkC P Small Multidrug Resistance protein
CINOAHEC_00607 4.1e-50 sugE P Small Multidrug Resistance protein
CINOAHEC_00608 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
CINOAHEC_00609 8.4e-270 ygaK C COG0277 FAD FMN-containing dehydrogenases
CINOAHEC_00610 1.2e-182 S Patatin-like phospholipase
CINOAHEC_00612 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CINOAHEC_00613 2.3e-119 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
CINOAHEC_00614 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
CINOAHEC_00615 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
CINOAHEC_00616 2.2e-154 malA S Protein of unknown function (DUF1189)
CINOAHEC_00617 3.9e-148 malD P transport
CINOAHEC_00618 2.9e-243 malC P COG1175 ABC-type sugar transport systems, permease components
CINOAHEC_00619 2.6e-233 mdxE G COG2182 Maltose-binding periplasmic proteins domains
CINOAHEC_00620 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
CINOAHEC_00621 1e-173 yvdE K Transcriptional regulator
CINOAHEC_00622 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
CINOAHEC_00623 2e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
CINOAHEC_00624 2.1e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
CINOAHEC_00625 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
CINOAHEC_00626 1.9e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CINOAHEC_00627 0.0 yxdM V ABC transporter (permease)
CINOAHEC_00628 7.3e-141 yvcR V ABC transporter, ATP-binding protein
CINOAHEC_00629 1.3e-196 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
CINOAHEC_00630 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CINOAHEC_00631 3.9e-33
CINOAHEC_00632 5.4e-141 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
CINOAHEC_00633 1.6e-36 crh G Phosphocarrier protein Chr
CINOAHEC_00634 1.4e-170 whiA K May be required for sporulation
CINOAHEC_00635 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
CINOAHEC_00636 5.7e-166 rapZ S Displays ATPase and GTPase activities
CINOAHEC_00637 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
CINOAHEC_00638 1.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CINOAHEC_00639 1.4e-102 usp CBM50 M protein conserved in bacteria
CINOAHEC_00640 2.4e-278 S COG0457 FOG TPR repeat
CINOAHEC_00641 0.0 msbA2 3.6.3.44 V ABC transporter
CINOAHEC_00643 4.5e-253
CINOAHEC_00644 2.3e-69
CINOAHEC_00645 3.1e-110 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
CINOAHEC_00646 4e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
CINOAHEC_00647 8.4e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CINOAHEC_00648 6.2e-114 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CINOAHEC_00649 4.7e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
CINOAHEC_00650 2.2e-227 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CINOAHEC_00651 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
CINOAHEC_00652 2.4e-220 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CINOAHEC_00653 1.5e-138 yvpB NU protein conserved in bacteria
CINOAHEC_00654 5.1e-119 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
CINOAHEC_00655 1.6e-80 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
CINOAHEC_00656 3.2e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
CINOAHEC_00657 5.3e-162 yvoD P COG0370 Fe2 transport system protein B
CINOAHEC_00658 2.7e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CINOAHEC_00659 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CINOAHEC_00660 3.9e-218 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
CINOAHEC_00661 5e-128 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CINOAHEC_00662 1.8e-133 yvoA K transcriptional
CINOAHEC_00663 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
CINOAHEC_00664 1.2e-50 yvlD S Membrane
CINOAHEC_00665 2.6e-26 pspB KT PspC domain
CINOAHEC_00666 2.4e-166 yvlB S Putative adhesin
CINOAHEC_00667 8e-49 yvlA
CINOAHEC_00668 5.7e-33 yvkN
CINOAHEC_00669 8.2e-49 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CINOAHEC_00670 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
CINOAHEC_00671 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CINOAHEC_00672 1.2e-30 csbA S protein conserved in bacteria
CINOAHEC_00673 0.0 yvkC 2.7.9.2 GT Phosphotransferase
CINOAHEC_00674 1.6e-100 yvkB K Transcriptional regulator
CINOAHEC_00675 1.6e-225 yvkA EGP Major facilitator Superfamily
CINOAHEC_00676 1.9e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CINOAHEC_00677 5.3e-56 swrA S Swarming motility protein
CINOAHEC_00678 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
CINOAHEC_00679 2.1e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
CINOAHEC_00680 1.6e-123 ftsE D cell division ATP-binding protein FtsE
CINOAHEC_00681 2e-55 cccB C COG2010 Cytochrome c, mono- and diheme variants
CINOAHEC_00682 9.3e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
CINOAHEC_00683 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CINOAHEC_00684 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CINOAHEC_00685 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CINOAHEC_00686 2.8e-66
CINOAHEC_00687 1.4e-08 fliT S bacterial-type flagellum organization
CINOAHEC_00688 1.1e-68 fliS N flagellar protein FliS
CINOAHEC_00689 2e-256 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CINOAHEC_00690 1.2e-55 flaG N flagellar protein FlaG
CINOAHEC_00691 1.4e-108 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CINOAHEC_00692 2.8e-29 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CINOAHEC_00693 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CINOAHEC_00694 5.7e-50 yviE
CINOAHEC_00695 7.8e-155 flgL N Belongs to the bacterial flagellin family
CINOAHEC_00696 2.7e-264 flgK N flagellar hook-associated protein
CINOAHEC_00697 3.8e-63 flgN NOU FlgN protein
CINOAHEC_00698 1.6e-39 flgM KNU Negative regulator of flagellin synthesis
CINOAHEC_00699 7e-74 yvyF S flagellar protein
CINOAHEC_00700 1.2e-126 comFC S Phosphoribosyl transferase domain
CINOAHEC_00701 1.1e-44 comFB S Late competence development protein ComFB
CINOAHEC_00702 6.4e-265 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CINOAHEC_00703 2.1e-154 degV S protein conserved in bacteria
CINOAHEC_00704 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CINOAHEC_00705 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
CINOAHEC_00706 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
CINOAHEC_00707 6e-163 yvhJ K Transcriptional regulator
CINOAHEC_00708 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
CINOAHEC_00709 3.2e-236 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
CINOAHEC_00710 4.7e-145 tuaG GT2 M Glycosyltransferase like family 2
CINOAHEC_00711 9.5e-113 tuaF M protein involved in exopolysaccharide biosynthesis
CINOAHEC_00712 1.8e-262 tuaE M Teichuronic acid biosynthesis protein
CINOAHEC_00713 2e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CINOAHEC_00714 5.3e-220 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
CINOAHEC_00715 1.3e-247 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CINOAHEC_00716 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
CINOAHEC_00717 3.3e-267 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
CINOAHEC_00718 0.0 lytB 3.5.1.28 D Stage II sporulation protein
CINOAHEC_00719 6e-38
CINOAHEC_00720 6.1e-163 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
CINOAHEC_00721 1.6e-216 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
CINOAHEC_00722 5.8e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
CINOAHEC_00723 1.1e-257 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
CINOAHEC_00724 7e-150 tagG GM Transport permease protein
CINOAHEC_00725 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CINOAHEC_00726 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
CINOAHEC_00727 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
CINOAHEC_00728 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
CINOAHEC_00729 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CINOAHEC_00730 4.3e-39
CINOAHEC_00731 3.5e-171
CINOAHEC_00732 4e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CINOAHEC_00733 2.5e-188 pmi 5.3.1.8 G mannose-6-phosphate isomerase
CINOAHEC_00734 3.8e-244 gerBA EG Spore germination protein
CINOAHEC_00735 4.7e-186 gerBB E Spore germination protein
CINOAHEC_00736 1.2e-197 gerAC S Spore germination protein
CINOAHEC_00737 4.1e-248 ywtG EGP Major facilitator Superfamily
CINOAHEC_00738 2.3e-168 ywtF K Transcriptional regulator
CINOAHEC_00739 4.2e-158 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
CINOAHEC_00740 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
CINOAHEC_00741 3.6e-21 ywtC
CINOAHEC_00742 6.3e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
CINOAHEC_00743 8.6e-70 pgsC S biosynthesis protein
CINOAHEC_00744 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
CINOAHEC_00745 9.3e-178 rbsR K transcriptional
CINOAHEC_00746 1.9e-161 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CINOAHEC_00747 4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
CINOAHEC_00748 3.3e-275 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
CINOAHEC_00749 1.3e-152 rbsC G Belongs to the binding-protein-dependent transport system permease family
CINOAHEC_00750 1.1e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
CINOAHEC_00751 3e-93 batE T Sh3 type 3 domain protein
CINOAHEC_00752 8e-48 ywsA S Protein of unknown function (DUF3892)
CINOAHEC_00753 9.7e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
CINOAHEC_00754 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
CINOAHEC_00755 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
CINOAHEC_00756 1.1e-169 alsR K LysR substrate binding domain
CINOAHEC_00757 7.2e-220 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CINOAHEC_00758 1.1e-124 ywrJ
CINOAHEC_00759 1.3e-209 cotH M Spore Coat
CINOAHEC_00760 3.7e-12
CINOAHEC_00761 1.1e-110 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CINOAHEC_00762 5e-54 S Domain of unknown function (DUF4181)
CINOAHEC_00763 2.3e-303 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
CINOAHEC_00764 8e-82 ywrC K Transcriptional regulator
CINOAHEC_00765 1.2e-103 ywrB P Chromate transporter
CINOAHEC_00766 9.9e-89 ywrA P COG2059 Chromate transport protein ChrA
CINOAHEC_00768 8.8e-101 ywqN S NAD(P)H-dependent
CINOAHEC_00769 4.2e-161 K Transcriptional regulator
CINOAHEC_00770 6.7e-117 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
CINOAHEC_00771 3.9e-25
CINOAHEC_00772 1e-241 ywqJ S Pre-toxin TG
CINOAHEC_00773 1.3e-38 ywqI S Family of unknown function (DUF5344)
CINOAHEC_00774 3.3e-15 S Domain of unknown function (DUF5082)
CINOAHEC_00775 4.9e-153 ywqG S Domain of unknown function (DUF1963)
CINOAHEC_00776 3.7e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CINOAHEC_00777 3e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
CINOAHEC_00778 2.2e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
CINOAHEC_00779 2e-116 ywqC M biosynthesis protein
CINOAHEC_00780 1.2e-17
CINOAHEC_00781 2.1e-307 ywqB S SWIM zinc finger
CINOAHEC_00782 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
CINOAHEC_00783 1.1e-153 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
CINOAHEC_00784 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
CINOAHEC_00785 3.7e-57 ssbB L Single-stranded DNA-binding protein
CINOAHEC_00786 1.9e-65 ywpG
CINOAHEC_00787 1.1e-66 ywpF S YwpF-like protein
CINOAHEC_00788 4e-50 srtA 3.4.22.70 M Sortase family
CINOAHEC_00789 1.2e-152 ywpD T Histidine kinase
CINOAHEC_00790 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
CINOAHEC_00791 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CINOAHEC_00792 2.6e-197 S aspartate phosphatase
CINOAHEC_00793 2.6e-141 flhP N flagellar basal body
CINOAHEC_00794 2.9e-124 flhO N flagellar basal body
CINOAHEC_00795 3.5e-180 mbl D Rod shape-determining protein
CINOAHEC_00796 3e-44 spoIIID K Stage III sporulation protein D
CINOAHEC_00797 2.1e-70 ywoH K COG1846 Transcriptional regulators
CINOAHEC_00798 2.7e-211 ywoG EGP Major facilitator Superfamily
CINOAHEC_00799 1.4e-230 ywoF P Right handed beta helix region
CINOAHEC_00800 4.4e-280 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
CINOAHEC_00801 3.1e-240 ywoD EGP Major facilitator superfamily
CINOAHEC_00802 1.5e-103 phzA Q Isochorismatase family
CINOAHEC_00803 8.3e-76
CINOAHEC_00804 3.3e-225 amt P Ammonium transporter
CINOAHEC_00805 1.6e-58 nrgB K Belongs to the P(II) protein family
CINOAHEC_00806 5.9e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
CINOAHEC_00807 2.4e-69 ywnJ S VanZ like family
CINOAHEC_00808 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
CINOAHEC_00809 2e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
CINOAHEC_00810 2.7e-14 ywnC S Family of unknown function (DUF5362)
CINOAHEC_00811 2.2e-70 ywnF S Family of unknown function (DUF5392)
CINOAHEC_00812 2.7e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CINOAHEC_00813 8.5e-142 mta K transcriptional
CINOAHEC_00814 2.6e-59 ywnC S Family of unknown function (DUF5362)
CINOAHEC_00815 1.1e-113 ywnB S NAD(P)H-binding
CINOAHEC_00816 2.8e-64 ywnA K Transcriptional regulator
CINOAHEC_00817 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
CINOAHEC_00818 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
CINOAHEC_00819 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
CINOAHEC_00820 3.2e-10 csbD K CsbD-like
CINOAHEC_00821 3e-84 ywmF S Peptidase M50
CINOAHEC_00822 1.3e-103 S response regulator aspartate phosphatase
CINOAHEC_00823 2e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CINOAHEC_00824 3.8e-145 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CINOAHEC_00826 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
CINOAHEC_00827 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
CINOAHEC_00828 3.5e-175 spoIID D Stage II sporulation protein D
CINOAHEC_00829 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CINOAHEC_00830 8.5e-131 ywmB S TATA-box binding
CINOAHEC_00831 1.3e-32 ywzB S membrane
CINOAHEC_00832 3.1e-86 ywmA
CINOAHEC_00833 8.5e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
CINOAHEC_00834 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CINOAHEC_00835 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CINOAHEC_00836 1.7e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CINOAHEC_00837 5.9e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CINOAHEC_00838 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CINOAHEC_00839 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CINOAHEC_00840 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
CINOAHEC_00841 2.5e-62 atpI S ATP synthase
CINOAHEC_00842 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CINOAHEC_00843 4.6e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CINOAHEC_00844 7.2e-95 ywlG S Belongs to the UPF0340 family
CINOAHEC_00845 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
CINOAHEC_00846 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CINOAHEC_00847 1.7e-91 mntP P Probably functions as a manganese efflux pump
CINOAHEC_00848 3.1e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
CINOAHEC_00849 2.1e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
CINOAHEC_00850 3e-111 spoIIR S stage II sporulation protein R
CINOAHEC_00851 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
CINOAHEC_00853 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
CINOAHEC_00854 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CINOAHEC_00855 3.8e-66 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CINOAHEC_00856 7.1e-90 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
CINOAHEC_00857 8.6e-160 ywkB S Membrane transport protein
CINOAHEC_00858 0.0 sfcA 1.1.1.38 C malic enzyme
CINOAHEC_00859 7e-104 tdk 2.7.1.21 F thymidine kinase
CINOAHEC_00860 1.1e-32 rpmE J Binds the 23S rRNA
CINOAHEC_00861 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CINOAHEC_00862 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
CINOAHEC_00863 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CINOAHEC_00864 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CINOAHEC_00865 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
CINOAHEC_00866 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
CINOAHEC_00867 2.3e-90 ywjG S Domain of unknown function (DUF2529)
CINOAHEC_00868 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
CINOAHEC_00869 4.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
CINOAHEC_00870 9.7e-211 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
CINOAHEC_00871 0.0 fadF C COG0247 Fe-S oxidoreductase
CINOAHEC_00872 2.3e-223 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
CINOAHEC_00873 2.1e-182 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
CINOAHEC_00874 2.7e-42 ywjC
CINOAHEC_00875 7.3e-91 ywjB H RibD C-terminal domain
CINOAHEC_00876 0.0 ywjA V ABC transporter
CINOAHEC_00877 3.2e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CINOAHEC_00878 2.6e-123 narI 1.7.5.1 C nitrate reductase, gamma
CINOAHEC_00879 2.4e-93 narJ 1.7.5.1 C nitrate reductase
CINOAHEC_00880 3.3e-296 narH 1.7.5.1 C Nitrate reductase, beta
CINOAHEC_00881 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CINOAHEC_00882 7e-86 arfM T cyclic nucleotide binding
CINOAHEC_00883 1.8e-138 ywiC S YwiC-like protein
CINOAHEC_00884 2e-129 fnr K helix_turn_helix, cAMP Regulatory protein
CINOAHEC_00885 1.3e-213 narK P COG2223 Nitrate nitrite transporter
CINOAHEC_00886 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
CINOAHEC_00887 4.7e-73 ywiB S protein conserved in bacteria
CINOAHEC_00888 1e-07 S Bacteriocin subtilosin A
CINOAHEC_00889 4.9e-270 C Fe-S oxidoreductases
CINOAHEC_00891 3.3e-132 cbiO V ABC transporter
CINOAHEC_00892 1.5e-234 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
CINOAHEC_00893 5.5e-217 2.7.1.26, 2.7.7.2 L Peptidase, M16
CINOAHEC_00894 1e-248 L Peptidase, M16
CINOAHEC_00896 1.8e-243 ywhL CO amine dehydrogenase activity
CINOAHEC_00897 2.7e-191 ywhK CO amine dehydrogenase activity
CINOAHEC_00898 2e-78 S aspartate phosphatase
CINOAHEC_00902 1.7e-20
CINOAHEC_00905 1.4e-57 V ATPases associated with a variety of cellular activities
CINOAHEC_00907 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
CINOAHEC_00908 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CINOAHEC_00909 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CINOAHEC_00910 3.4e-94 ywhD S YwhD family
CINOAHEC_00911 5.1e-119 ywhC S Peptidase family M50
CINOAHEC_00912 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
CINOAHEC_00913 9.5e-71 ywhA K Transcriptional regulator
CINOAHEC_00914 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CINOAHEC_00916 9.7e-237 mmr U Major Facilitator Superfamily
CINOAHEC_00917 6.9e-78 yffB K Transcriptional regulator
CINOAHEC_00918 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
CINOAHEC_00919 5.1e-256 ywfO S COG1078 HD superfamily phosphohydrolases
CINOAHEC_00920 3.1e-36 ywzC S Belongs to the UPF0741 family
CINOAHEC_00921 5.1e-110 rsfA_1
CINOAHEC_00922 9.2e-156 ywfM EG EamA-like transporter family
CINOAHEC_00923 5.6e-155 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
CINOAHEC_00924 1.1e-156 cysL K Transcriptional regulator
CINOAHEC_00925 1.6e-174 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
CINOAHEC_00926 1.1e-146 ywfI C May function as heme-dependent peroxidase
CINOAHEC_00927 2.2e-137 IQ Enoyl-(Acyl carrier protein) reductase
CINOAHEC_00928 1.6e-232 ywfG 2.6.1.83 E Aminotransferase class I and II
CINOAHEC_00929 7.3e-209 bacE EGP Major facilitator Superfamily
CINOAHEC_00930 4e-270 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
CINOAHEC_00931 1.1e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CINOAHEC_00932 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
CINOAHEC_00933 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
CINOAHEC_00934 2.3e-205 ywfA EGP Major facilitator Superfamily
CINOAHEC_00935 4e-262 lysP E amino acid
CINOAHEC_00936 0.0 rocB E arginine degradation protein
CINOAHEC_00937 6e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
CINOAHEC_00938 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
CINOAHEC_00939 1.2e-77
CINOAHEC_00940 3.5e-87 spsL 5.1.3.13 M Spore Coat
CINOAHEC_00941 2.2e-159 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
CINOAHEC_00942 1.1e-180 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CINOAHEC_00943 9.3e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CINOAHEC_00944 9.7e-186 spsG M Spore Coat
CINOAHEC_00945 5e-128 spsF M Spore Coat
CINOAHEC_00946 3.3e-211 spsE 2.5.1.56 M acid synthase
CINOAHEC_00947 1.2e-163 spsD 2.3.1.210 K Spore Coat
CINOAHEC_00948 3e-223 spsC E Belongs to the DegT DnrJ EryC1 family
CINOAHEC_00949 2.6e-266 spsB M Capsule polysaccharide biosynthesis protein
CINOAHEC_00950 1.8e-144 spsA M Spore Coat
CINOAHEC_00951 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
CINOAHEC_00952 4.3e-59 ywdK S small membrane protein
CINOAHEC_00953 3.7e-238 ywdJ F Xanthine uracil
CINOAHEC_00954 5e-48 ywdI S Family of unknown function (DUF5327)
CINOAHEC_00955 4.7e-260 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
CINOAHEC_00956 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CINOAHEC_00957 6.1e-151 ywdF GT2,GT4 S Glycosyltransferase like family 2
CINOAHEC_00958 9.3e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
CINOAHEC_00959 2e-28 ywdA
CINOAHEC_00960 9.5e-296 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
CINOAHEC_00961 3.9e-254 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CINOAHEC_00962 1e-139 focA P Formate/nitrite transporter
CINOAHEC_00963 7e-150 sacT K transcriptional antiterminator
CINOAHEC_00965 0.0 vpr O Belongs to the peptidase S8 family
CINOAHEC_00966 1.5e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CINOAHEC_00967 1e-136 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
CINOAHEC_00968 2.9e-202 rodA D Belongs to the SEDS family
CINOAHEC_00969 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
CINOAHEC_00970 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
CINOAHEC_00971 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
CINOAHEC_00972 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CINOAHEC_00973 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
CINOAHEC_00974 1e-35 ywzA S membrane
CINOAHEC_00975 1.3e-303 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
CINOAHEC_00976 6.2e-229 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CINOAHEC_00977 9.5e-60 gtcA S GtrA-like protein
CINOAHEC_00978 2.2e-122 ywcC K transcriptional regulator
CINOAHEC_00980 1.1e-47 ywcB S Protein of unknown function, DUF485
CINOAHEC_00981 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CINOAHEC_00982 8e-45 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
CINOAHEC_00983 2.1e-58 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
CINOAHEC_00984 2.6e-225 ywbN P Dyp-type peroxidase family protein
CINOAHEC_00985 2.9e-186 ycdO P periplasmic lipoprotein involved in iron transport
CINOAHEC_00986 4.5e-253 P COG0672 High-affinity Fe2 Pb2 permease
CINOAHEC_00987 7.2e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
CINOAHEC_00988 8.2e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CINOAHEC_00989 4.3e-153 ywbI K Transcriptional regulator
CINOAHEC_00990 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
CINOAHEC_00991 2.3e-111 ywbG M effector of murein hydrolase
CINOAHEC_00992 8.1e-208 ywbF EGP Major facilitator Superfamily
CINOAHEC_00993 1.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
CINOAHEC_00994 2e-219 ywbD 2.1.1.191 J Methyltransferase
CINOAHEC_00995 4.9e-66 ywbC 4.4.1.5 E glyoxalase
CINOAHEC_00996 2.6e-95 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
CINOAHEC_00997 3.1e-124 ywbB S Protein of unknown function (DUF2711)
CINOAHEC_00998 5.6e-242 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CINOAHEC_00999 2.3e-273 epr 3.4.21.62 O Belongs to the peptidase S8 family
CINOAHEC_01000 2e-242 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CINOAHEC_01001 2.1e-149 sacY K transcriptional antiterminator
CINOAHEC_01002 4.5e-168 gspA M General stress
CINOAHEC_01003 1.1e-124 ywaF S Integral membrane protein
CINOAHEC_01004 2.3e-87 ywaE K Transcriptional regulator
CINOAHEC_01005 3.7e-232 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CINOAHEC_01006 4.9e-249 ywaD 3.4.11.10, 3.4.11.6 S PA domain
CINOAHEC_01007 5.3e-92 K Helix-turn-helix XRE-family like proteins
CINOAHEC_01008 2.1e-48 4.1.1.44 S Carboxymuconolactone decarboxylase family
CINOAHEC_01009 1e-130 ynfM EGP Major facilitator Superfamily
CINOAHEC_01010 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
CINOAHEC_01011 2.3e-165 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
CINOAHEC_01012 7.4e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CINOAHEC_01013 1.2e-232 dltB M membrane protein involved in D-alanine export
CINOAHEC_01014 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CINOAHEC_01015 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CINOAHEC_01016 2.8e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
CINOAHEC_01017 6.9e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
CINOAHEC_01018 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
CINOAHEC_01019 1.9e-37 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
CINOAHEC_01020 2.8e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CINOAHEC_01021 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
CINOAHEC_01022 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
CINOAHEC_01023 1.1e-19 yxzF
CINOAHEC_01024 2.9e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
CINOAHEC_01025 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
CINOAHEC_01026 3e-210 yxlH EGP Major facilitator Superfamily
CINOAHEC_01027 2.8e-137 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
CINOAHEC_01028 2.4e-164 yxlF V ABC transporter, ATP-binding protein
CINOAHEC_01029 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
CINOAHEC_01030 1.4e-30
CINOAHEC_01031 1.9e-47 yxlC S Family of unknown function (DUF5345)
CINOAHEC_01032 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
CINOAHEC_01033 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
CINOAHEC_01034 7.7e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CINOAHEC_01035 0.0 cydD V ATP-binding protein
CINOAHEC_01036 9.4e-311 cydD V ATP-binding
CINOAHEC_01037 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
CINOAHEC_01038 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
CINOAHEC_01039 2.1e-228 cimH C COG3493 Na citrate symporter
CINOAHEC_01040 1.3e-307 3.4.24.84 O Peptidase family M48
CINOAHEC_01042 4.7e-154 yxkH G Polysaccharide deacetylase
CINOAHEC_01043 5.9e-205 msmK P Belongs to the ABC transporter superfamily
CINOAHEC_01044 5.4e-164 lrp QT PucR C-terminal helix-turn-helix domain
CINOAHEC_01045 2e-269 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CINOAHEC_01046 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
CINOAHEC_01047 4.4e-137
CINOAHEC_01048 5.7e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
CINOAHEC_01049 7.7e-77 S Protein of unknown function (DUF1453)
CINOAHEC_01050 5.9e-190 yxjM T Signal transduction histidine kinase
CINOAHEC_01051 7.8e-112 K helix_turn_helix, Lux Regulon
CINOAHEC_01052 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
CINOAHEC_01055 7.1e-86 yxjI S LURP-one-related
CINOAHEC_01056 2.3e-220 yxjG 2.1.1.14 E Methionine synthase
CINOAHEC_01057 1.7e-218 yxjG 2.1.1.14 E Methionine synthase
CINOAHEC_01058 2.8e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
CINOAHEC_01059 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
CINOAHEC_01060 2e-129 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CINOAHEC_01061 2.2e-252 yxjC EG COG2610 H gluconate symporter and related permeases
CINOAHEC_01062 9.6e-155 rlmA 2.1.1.187 Q Methyltransferase domain
CINOAHEC_01063 1.2e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CINOAHEC_01064 9.8e-102 T Domain of unknown function (DUF4163)
CINOAHEC_01065 3e-47 yxiS
CINOAHEC_01066 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
CINOAHEC_01067 6.6e-224 citH C Citrate transporter
CINOAHEC_01068 5e-144 exoK GH16 M licheninase activity
CINOAHEC_01069 8.3e-151 licT K transcriptional antiterminator
CINOAHEC_01070 1.5e-110
CINOAHEC_01071 4.3e-231 yxiO S COG2270 Permeases of the major facilitator superfamily
CINOAHEC_01072 2.1e-263 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
CINOAHEC_01073 8.9e-212 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
CINOAHEC_01076 4.7e-40 yxiJ S YxiJ-like protein
CINOAHEC_01077 6.3e-82 yxiI S Protein of unknown function (DUF2716)
CINOAHEC_01078 3.3e-139
CINOAHEC_01079 5.1e-69 yxiG
CINOAHEC_01080 7.3e-59
CINOAHEC_01081 3.8e-84
CINOAHEC_01082 1.5e-71 yxxG
CINOAHEC_01083 0.0 wapA M COG3209 Rhs family protein
CINOAHEC_01084 2.5e-164 yxxF EG EamA-like transporter family
CINOAHEC_01085 5.4e-72 yxiE T Belongs to the universal stress protein A family
CINOAHEC_01086 2.1e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CINOAHEC_01087 1.5e-309 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CINOAHEC_01088 2.2e-48
CINOAHEC_01089 2.9e-78 S SMI1 / KNR4 family
CINOAHEC_01090 2.2e-56 S nuclease activity
CINOAHEC_01091 9.2e-145 S nuclease activity
CINOAHEC_01093 7.3e-19 S Protein conserved in bacteria
CINOAHEC_01095 3.5e-126 S nuclease activity
CINOAHEC_01096 1.4e-38 yxiC S Family of unknown function (DUF5344)
CINOAHEC_01097 5.1e-20 S Domain of unknown function (DUF5082)
CINOAHEC_01098 1.5e-277 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
CINOAHEC_01099 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
CINOAHEC_01100 4.4e-283 hutH 4.3.1.3 E Histidine ammonia-lyase
CINOAHEC_01101 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CINOAHEC_01102 7e-234 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
CINOAHEC_01103 5.7e-180 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
CINOAHEC_01104 2.6e-250 lysP E amino acid
CINOAHEC_01105 3.6e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
CINOAHEC_01106 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CINOAHEC_01107 7.7e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CINOAHEC_01108 2.3e-173 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
CINOAHEC_01109 4.4e-152 yxxB S Domain of Unknown Function (DUF1206)
CINOAHEC_01110 1.4e-198 eutH E Ethanolamine utilisation protein, EutH
CINOAHEC_01111 5.1e-251 yxeQ S MmgE/PrpD family
CINOAHEC_01112 6.1e-213 yxeP 3.5.1.47 E hydrolase activity
CINOAHEC_01113 5.9e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
CINOAHEC_01114 1.2e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
CINOAHEC_01115 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
CINOAHEC_01116 8.9e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CINOAHEC_01117 6.3e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CINOAHEC_01118 7.7e-188 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
CINOAHEC_01119 1.8e-150 yidA S hydrolases of the HAD superfamily
CINOAHEC_01122 1.3e-20 yxeE
CINOAHEC_01123 5.6e-16 yxeD
CINOAHEC_01124 8.5e-69
CINOAHEC_01125 6.6e-176 fhuD P ABC transporter
CINOAHEC_01126 3.4e-58 yxeA S Protein of unknown function (DUF1093)
CINOAHEC_01127 0.0 yxdM V ABC transporter (permease)
CINOAHEC_01128 9.4e-141 yxdL V ABC transporter, ATP-binding protein
CINOAHEC_01129 3.4e-180 T PhoQ Sensor
CINOAHEC_01130 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CINOAHEC_01131 4.6e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
CINOAHEC_01132 1.6e-138 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
CINOAHEC_01133 8.6e-167 iolH G Xylose isomerase-like TIM barrel
CINOAHEC_01134 8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
CINOAHEC_01135 2.1e-233 iolF EGP Major facilitator Superfamily
CINOAHEC_01136 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
CINOAHEC_01137 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
CINOAHEC_01138 7.1e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
CINOAHEC_01139 3.5e-154 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
CINOAHEC_01140 3.9e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CINOAHEC_01141 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
CINOAHEC_01142 8.3e-176 iolS C Aldo keto reductase
CINOAHEC_01144 8.3e-48 yxcD S Protein of unknown function (DUF2653)
CINOAHEC_01145 9.6e-245 csbC EGP Major facilitator Superfamily
CINOAHEC_01146 0.0 htpG O Molecular chaperone. Has ATPase activity
CINOAHEC_01148 1e-148 IQ Enoyl-(Acyl carrier protein) reductase
CINOAHEC_01149 1.7e-207 yxbF K Bacterial regulatory proteins, tetR family
CINOAHEC_01150 2.4e-245 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
CINOAHEC_01151 6.3e-31 yxaI S membrane protein domain
CINOAHEC_01152 9.9e-92 S PQQ-like domain
CINOAHEC_01153 1.2e-59 S Family of unknown function (DUF5391)
CINOAHEC_01154 1.4e-75 yxaI S membrane protein domain
CINOAHEC_01155 1.1e-223 P Protein of unknown function (DUF418)
CINOAHEC_01156 2.4e-197 yxaG 1.13.11.24 S AraC-like ligand binding domain
CINOAHEC_01157 7.1e-101 yxaF K Transcriptional regulator
CINOAHEC_01158 7.3e-200 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CINOAHEC_01159 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
CINOAHEC_01160 5.2e-50 S LrgA family
CINOAHEC_01161 2.6e-118 yxaC M effector of murein hydrolase
CINOAHEC_01162 3.7e-193 yxaB GM Polysaccharide pyruvyl transferase
CINOAHEC_01163 5.6e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
CINOAHEC_01164 2.1e-126 gntR K transcriptional
CINOAHEC_01165 1.1e-302 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
CINOAHEC_01166 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
CINOAHEC_01167 2.5e-272 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CINOAHEC_01168 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
CINOAHEC_01169 3.8e-287 ahpF O Alkyl hydroperoxide reductase
CINOAHEC_01171 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
CINOAHEC_01172 1.8e-84 dam2 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
CINOAHEC_01173 8.5e-52 K DNA binding
CINOAHEC_01174 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CINOAHEC_01175 1.1e-09 S YyzF-like protein
CINOAHEC_01176 1e-69
CINOAHEC_01177 9.6e-166 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
CINOAHEC_01178 4.3e-55 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
CINOAHEC_01180 5.7e-31 yycQ S Protein of unknown function (DUF2651)
CINOAHEC_01181 3.1e-204 yycP
CINOAHEC_01182 3.8e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CINOAHEC_01183 5.8e-85 yycN 2.3.1.128 K Acetyltransferase
CINOAHEC_01184 5e-188 S aspartate phosphatase
CINOAHEC_01186 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
CINOAHEC_01187 1.3e-260 rocE E amino acid
CINOAHEC_01188 1.7e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
CINOAHEC_01189 7.4e-16
CINOAHEC_01190 9.6e-95
CINOAHEC_01191 5.1e-40 S Sporulation delaying protein SdpA
CINOAHEC_01192 1.1e-59 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
CINOAHEC_01193 1.2e-40 sdpR K transcriptional
CINOAHEC_01194 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
CINOAHEC_01195 8.4e-221 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CINOAHEC_01196 8.7e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
CINOAHEC_01197 7.3e-155 yycI S protein conserved in bacteria
CINOAHEC_01198 3.6e-260 yycH S protein conserved in bacteria
CINOAHEC_01199 0.0 vicK 2.7.13.3 T Histidine kinase
CINOAHEC_01200 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CINOAHEC_01205 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CINOAHEC_01206 5.8e-76 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CINOAHEC_01207 1.2e-250 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
CINOAHEC_01208 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
CINOAHEC_01210 1.9e-15 yycC K YycC-like protein
CINOAHEC_01211 8.4e-221 yeaN P COG2807 Cyanate permease
CINOAHEC_01212 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CINOAHEC_01213 2.2e-73 rplI J binds to the 23S rRNA
CINOAHEC_01214 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
CINOAHEC_01215 3.2e-159 yybS S membrane
CINOAHEC_01217 3.3e-83 cotF M Spore coat protein
CINOAHEC_01218 7.5e-67 ydeP3 K Transcriptional regulator
CINOAHEC_01219 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
CINOAHEC_01220 1.5e-58
CINOAHEC_01222 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
CINOAHEC_01223 6.3e-110 K TipAS antibiotic-recognition domain
CINOAHEC_01224 1.1e-123
CINOAHEC_01225 2.9e-66 yybH S SnoaL-like domain
CINOAHEC_01226 1.6e-122 yybG S Pentapeptide repeat-containing protein
CINOAHEC_01227 3.1e-215 ynfM EGP Major facilitator Superfamily
CINOAHEC_01228 6.9e-164 yybE K Transcriptional regulator
CINOAHEC_01229 5.5e-77 yjcF S Acetyltransferase (GNAT) domain
CINOAHEC_01230 2.3e-73 yybC
CINOAHEC_01231 7.3e-126 S Metallo-beta-lactamase superfamily
CINOAHEC_01232 5.6e-77 yybA 2.3.1.57 K transcriptional
CINOAHEC_01233 2e-71 yjcF S Acetyltransferase (GNAT) domain
CINOAHEC_01234 5.5e-96 yyaS S Membrane
CINOAHEC_01235 1.6e-91 yyaR K Acetyltransferase (GNAT) domain
CINOAHEC_01236 1.3e-65 yyaQ S YjbR
CINOAHEC_01237 2.1e-105 yyaP 1.5.1.3 H RibD C-terminal domain
CINOAHEC_01238 6.6e-246 tetL EGP Major facilitator Superfamily
CINOAHEC_01239 9.7e-44 yyaL O Highly conserved protein containing a thioredoxin domain
CINOAHEC_01240 1.5e-60 yyaN K MerR HTH family regulatory protein
CINOAHEC_01241 4.4e-161 yyaM EG EamA-like transporter family
CINOAHEC_01242 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
CINOAHEC_01243 8e-168 yyaK S CAAX protease self-immunity
CINOAHEC_01244 2.6e-242 EGP Major facilitator superfamily
CINOAHEC_01245 8.1e-94 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
CINOAHEC_01246 8.9e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CINOAHEC_01247 3.6e-179 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
CINOAHEC_01248 5.8e-143 xth 3.1.11.2 L exodeoxyribonuclease III
CINOAHEC_01249 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CINOAHEC_01250 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CINOAHEC_01251 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
CINOAHEC_01252 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
CINOAHEC_01253 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CINOAHEC_01254 2.3e-33 yyzM S protein conserved in bacteria
CINOAHEC_01255 8.1e-177 yyaD S Membrane
CINOAHEC_01256 2.8e-111 yyaC S Sporulation protein YyaC
CINOAHEC_01257 2.1e-149 spo0J K Belongs to the ParB family
CINOAHEC_01258 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
CINOAHEC_01259 1.6e-73 S Bacterial PH domain
CINOAHEC_01260 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
CINOAHEC_01261 5.3e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
CINOAHEC_01262 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
CINOAHEC_01263 3.7e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CINOAHEC_01264 6.5e-108 jag S single-stranded nucleic acid binding R3H
CINOAHEC_01265 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CINOAHEC_01266 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
CINOAHEC_01267 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CINOAHEC_01268 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CINOAHEC_01269 2.4e-33 yaaA S S4 domain
CINOAHEC_01270 5.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CINOAHEC_01271 1.8e-37 yaaB S Domain of unknown function (DUF370)
CINOAHEC_01272 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CINOAHEC_01273 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CINOAHEC_01274 1.4e-43 L COG3666 Transposase and inactivated derivatives
CINOAHEC_01282 7.8e-08
CINOAHEC_01290 2e-08
CINOAHEC_01294 2.7e-143 spo0M S COG4326 Sporulation control protein
CINOAHEC_01295 3e-27
CINOAHEC_01296 1.3e-133 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
CINOAHEC_01297 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CINOAHEC_01298 2.2e-262 ygaK C Berberine and berberine like
CINOAHEC_01300 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
CINOAHEC_01301 3.7e-137 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
CINOAHEC_01302 1.8e-168 ssuA M Sulfonate ABC transporter
CINOAHEC_01303 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
CINOAHEC_01304 2e-216 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
CINOAHEC_01306 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CINOAHEC_01307 4.1e-78 ygaO
CINOAHEC_01308 4.4e-29 K Transcriptional regulator
CINOAHEC_01310 3.9e-113 yhzB S B3/4 domain
CINOAHEC_01311 1.7e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CINOAHEC_01312 1.8e-175 yhbB S Putative amidase domain
CINOAHEC_01313 9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
CINOAHEC_01314 1.3e-108 yhbD K Protein of unknown function (DUF4004)
CINOAHEC_01315 5.9e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
CINOAHEC_01316 2.1e-70 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
CINOAHEC_01317 0.0 prkA T Ser protein kinase
CINOAHEC_01318 2.5e-225 yhbH S Belongs to the UPF0229 family
CINOAHEC_01319 2.2e-76 yhbI K DNA-binding transcription factor activity
CINOAHEC_01320 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
CINOAHEC_01321 3.1e-271 yhcA EGP Major facilitator Superfamily
CINOAHEC_01322 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
CINOAHEC_01323 2.8e-37 yhcC
CINOAHEC_01324 7.8e-55
CINOAHEC_01325 6.6e-60 yhcF K Transcriptional regulator
CINOAHEC_01326 1.6e-123 yhcG V ABC transporter, ATP-binding protein
CINOAHEC_01327 1e-165 yhcH V ABC transporter, ATP-binding protein
CINOAHEC_01328 8.7e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
CINOAHEC_01329 1e-30 cspB K Cold-shock protein
CINOAHEC_01330 5.2e-153 metQ M Belongs to the nlpA lipoprotein family
CINOAHEC_01331 3.4e-197 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
CINOAHEC_01332 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CINOAHEC_01333 1.1e-40 yhcM
CINOAHEC_01334 2.1e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
CINOAHEC_01335 1.2e-147 yhcP
CINOAHEC_01336 1.5e-99 yhcQ M Spore coat protein
CINOAHEC_01337 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
CINOAHEC_01338 8.7e-102 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
CINOAHEC_01339 4.3e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CINOAHEC_01340 9.3e-68 yhcU S Family of unknown function (DUF5365)
CINOAHEC_01341 9.9e-68 yhcV S COG0517 FOG CBS domain
CINOAHEC_01342 1.3e-119 yhcW 5.4.2.6 S hydrolase
CINOAHEC_01343 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
CINOAHEC_01344 1.6e-260 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CINOAHEC_01345 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CINOAHEC_01346 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
CINOAHEC_01347 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CINOAHEC_01348 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CINOAHEC_01349 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
CINOAHEC_01350 8.8e-212 yhcY 2.7.13.3 T Histidine kinase
CINOAHEC_01351 1.9e-110 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CINOAHEC_01352 3.2e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
CINOAHEC_01353 1.2e-38 yhdB S YhdB-like protein
CINOAHEC_01354 4.8e-54 yhdC S Protein of unknown function (DUF3889)
CINOAHEC_01355 4.3e-187 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
CINOAHEC_01356 1e-75 nsrR K Transcriptional regulator
CINOAHEC_01357 1.5e-238 ygxB M Conserved TM helix
CINOAHEC_01358 2.1e-276 ycgB S Stage V sporulation protein R
CINOAHEC_01359 1.3e-257 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
CINOAHEC_01360 5.3e-128 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
CINOAHEC_01361 3.8e-162 citR K Transcriptional regulator
CINOAHEC_01362 2.6e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
CINOAHEC_01363 9.2e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CINOAHEC_01364 3.4e-250 yhdG E amino acid
CINOAHEC_01365 2.8e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
CINOAHEC_01366 7.4e-269 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CINOAHEC_01367 2e-76 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CINOAHEC_01368 8.1e-45 yhdK S Sigma-M inhibitor protein
CINOAHEC_01369 2.5e-200 yhdL S Sigma factor regulator N-terminal
CINOAHEC_01370 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
CINOAHEC_01371 1.5e-191 yhdN C Aldo keto reductase
CINOAHEC_01372 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
CINOAHEC_01373 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
CINOAHEC_01374 4.2e-74 cueR K transcriptional
CINOAHEC_01375 2.6e-222 yhdR 2.6.1.1 E Aminotransferase
CINOAHEC_01376 7.1e-240 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
CINOAHEC_01377 1.4e-43 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CINOAHEC_01378 9.6e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CINOAHEC_01379 1.2e-134 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
CINOAHEC_01381 5.6e-203 yhdY M Mechanosensitive ion channel
CINOAHEC_01382 2.6e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
CINOAHEC_01383 1.9e-150 yheN G deacetylase
CINOAHEC_01384 3.4e-152 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
CINOAHEC_01385 3.5e-231 nhaC C Na H antiporter
CINOAHEC_01386 7.6e-84 nhaX T Belongs to the universal stress protein A family
CINOAHEC_01387 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
CINOAHEC_01388 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
CINOAHEC_01389 2.4e-110 yheG GM NAD(P)H-binding
CINOAHEC_01390 6.3e-28 sspB S spore protein
CINOAHEC_01391 1.3e-36 yheE S Family of unknown function (DUF5342)
CINOAHEC_01392 1e-267 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
CINOAHEC_01393 7.4e-216 yheC HJ YheC/D like ATP-grasp
CINOAHEC_01394 1.4e-201 yheB S Belongs to the UPF0754 family
CINOAHEC_01395 9.5e-48 yheA S Belongs to the UPF0342 family
CINOAHEC_01396 1.5e-205 yhaZ L DNA alkylation repair enzyme
CINOAHEC_01397 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
CINOAHEC_01398 1.8e-292 hemZ H coproporphyrinogen III oxidase
CINOAHEC_01399 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
CINOAHEC_01400 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
CINOAHEC_01402 6.7e-131 yhaR 5.3.3.18 I enoyl-CoA hydratase
CINOAHEC_01403 2.4e-26 S YhzD-like protein
CINOAHEC_01404 5.2e-167 yhaQ S ABC transporter, ATP-binding protein
CINOAHEC_01405 6.1e-214 yhaP CP COG1668 ABC-type Na efflux pump, permease component
CINOAHEC_01406 9.7e-225 yhaO L DNA repair exonuclease
CINOAHEC_01407 0.0 yhaN L AAA domain
CINOAHEC_01408 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
CINOAHEC_01409 1.6e-21 yhaL S Sporulation protein YhaL
CINOAHEC_01410 3.2e-116 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
CINOAHEC_01411 7.3e-89 yhaK S Putative zincin peptidase
CINOAHEC_01412 1.3e-54 yhaI S Protein of unknown function (DUF1878)
CINOAHEC_01413 1e-113 hpr K Negative regulator of protease production and sporulation
CINOAHEC_01414 7e-39 yhaH S YtxH-like protein
CINOAHEC_01415 5.4e-21
CINOAHEC_01416 3.1e-79 trpP S Tryptophan transporter TrpP
CINOAHEC_01417 5.4e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CINOAHEC_01418 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
CINOAHEC_01419 4.6e-137 ecsA V transporter (ATP-binding protein)
CINOAHEC_01420 2e-214 ecsB U ABC transporter
CINOAHEC_01421 4.6e-110 ecsC S EcsC protein family
CINOAHEC_01422 3.1e-228 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
CINOAHEC_01423 1.1e-245 yhfA C membrane
CINOAHEC_01424 1e-32 1.15.1.2 C Rubrerythrin
CINOAHEC_01425 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
CINOAHEC_01426 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CINOAHEC_01427 4.1e-203 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CINOAHEC_01428 1.8e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
CINOAHEC_01429 4.1e-267 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CINOAHEC_01430 5.4e-101 yhgD K Transcriptional regulator
CINOAHEC_01431 3e-214 yhgE S YhgE Pip N-terminal domain protein
CINOAHEC_01432 1.1e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CINOAHEC_01433 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
CINOAHEC_01434 3e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
CINOAHEC_01435 3.7e-72 3.4.13.21 S ASCH
CINOAHEC_01436 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CINOAHEC_01437 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
CINOAHEC_01438 4.9e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
CINOAHEC_01439 5e-111 yhfK GM NmrA-like family
CINOAHEC_01440 5.4e-300 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
CINOAHEC_01441 1.9e-65 yhfM
CINOAHEC_01442 5.9e-241 yhfN 3.4.24.84 O Peptidase M48
CINOAHEC_01443 2.3e-204 aprE 3.4.21.62 O Belongs to the peptidase S8 family
CINOAHEC_01444 8.1e-76 VY92_01935 K acetyltransferase
CINOAHEC_01445 7e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
CINOAHEC_01446 4.3e-159 yfmC M Periplasmic binding protein
CINOAHEC_01447 2.1e-108 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
CINOAHEC_01448 1.1e-195 vraB 2.3.1.9 I Belongs to the thiolase family
CINOAHEC_01449 1.2e-271 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
CINOAHEC_01450 5e-91 bioY S BioY family
CINOAHEC_01451 6.3e-182 hemAT NT chemotaxis protein
CINOAHEC_01452 2.3e-300 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
CINOAHEC_01453 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CINOAHEC_01454 1.3e-32 yhzC S IDEAL
CINOAHEC_01455 4.2e-109 comK K Competence transcription factor
CINOAHEC_01456 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
CINOAHEC_01457 7.8e-42 yhjA S Excalibur calcium-binding domain
CINOAHEC_01458 6.1e-266 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CINOAHEC_01459 6.9e-27 yhjC S Protein of unknown function (DUF3311)
CINOAHEC_01460 5e-60 yhjD
CINOAHEC_01461 2e-109 yhjE S SNARE associated Golgi protein
CINOAHEC_01462 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
CINOAHEC_01463 1.2e-280 yhjG CH FAD binding domain
CINOAHEC_01464 4.5e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
CINOAHEC_01465 3.8e-213 glcP G Major Facilitator Superfamily
CINOAHEC_01466 6e-199 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
CINOAHEC_01467 2.6e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
CINOAHEC_01468 1.8e-253 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
CINOAHEC_01469 1.7e-187 yhjM 5.1.1.1 K Transcriptional regulator
CINOAHEC_01470 1.9e-201 abrB S membrane
CINOAHEC_01471 9e-215 EGP Transmembrane secretion effector
CINOAHEC_01472 0.0 S Sugar transport-related sRNA regulator N-term
CINOAHEC_01473 2e-36 yhjQ C COG1145 Ferredoxin
CINOAHEC_01474 2.2e-78 yhjR S Rubrerythrin
CINOAHEC_01475 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
CINOAHEC_01476 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
CINOAHEC_01477 1.7e-221 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
CINOAHEC_01478 0.0 sbcC L COG0419 ATPase involved in DNA repair
CINOAHEC_01479 3e-50 yisB V COG1403 Restriction endonuclease
CINOAHEC_01480 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
CINOAHEC_01481 3e-66 gerPE S Spore germination protein GerPE
CINOAHEC_01482 6.3e-24 gerPD S Spore germination protein
CINOAHEC_01483 1.8e-54 gerPC S Spore germination protein
CINOAHEC_01484 4e-34 gerPB S cell differentiation
CINOAHEC_01485 1.9e-33 gerPA S Spore germination protein
CINOAHEC_01486 1.5e-22 yisI S Spo0E like sporulation regulatory protein
CINOAHEC_01487 2.5e-172 cotH M Spore Coat
CINOAHEC_01488 5.4e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
CINOAHEC_01489 6.6e-57 yisL S UPF0344 protein
CINOAHEC_01490 0.0 wprA O Belongs to the peptidase S8 family
CINOAHEC_01491 1.3e-102 yisN S Protein of unknown function (DUF2777)
CINOAHEC_01492 0.0 asnO 6.3.5.4 E Asparagine synthase
CINOAHEC_01493 6.4e-88 yizA S Damage-inducible protein DinB
CINOAHEC_01494 1.7e-148 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
CINOAHEC_01495 1.5e-242 yisQ V Mate efflux family protein
CINOAHEC_01496 3.5e-160 yisR K Transcriptional regulator
CINOAHEC_01497 6.9e-184 purR K helix_turn _helix lactose operon repressor
CINOAHEC_01498 3.7e-193 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
CINOAHEC_01499 5.3e-92 yisT S DinB family
CINOAHEC_01500 2.7e-106 argO S Lysine exporter protein LysE YggA
CINOAHEC_01501 3.1e-278 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CINOAHEC_01502 6.8e-36 mcbG S Pentapeptide repeats (9 copies)
CINOAHEC_01503 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
CINOAHEC_01504 1.4e-112 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
CINOAHEC_01505 7.4e-230 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
CINOAHEC_01506 2.1e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
CINOAHEC_01507 1.9e-121 comB 3.1.3.71 H Belongs to the ComB family
CINOAHEC_01508 1.9e-141 yitD 4.4.1.19 S synthase
CINOAHEC_01509 7.2e-113 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
CINOAHEC_01510 4.6e-221 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
CINOAHEC_01511 1.5e-228 yitG EGP Major facilitator Superfamily
CINOAHEC_01512 5.1e-156 yitH K Acetyltransferase (GNAT) domain
CINOAHEC_01513 1.3e-81 yjcF S Acetyltransferase (GNAT) domain
CINOAHEC_01514 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
CINOAHEC_01515 3.3e-54 yajQ S Belongs to the UPF0234 family
CINOAHEC_01516 4e-161 cvfB S protein conserved in bacteria
CINOAHEC_01517 8.5e-94
CINOAHEC_01518 3.6e-171
CINOAHEC_01519 1.5e-97 S Sporulation delaying protein SdpA
CINOAHEC_01520 1.5e-58 K Transcriptional regulator PadR-like family
CINOAHEC_01521 5e-94
CINOAHEC_01522 1.4e-44 yitR S Domain of unknown function (DUF3784)
CINOAHEC_01523 1.1e-308 nprB 3.4.24.28 E Peptidase M4
CINOAHEC_01524 2.7e-157 yitS S protein conserved in bacteria
CINOAHEC_01525 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
CINOAHEC_01526 1.7e-73 ipi S Intracellular proteinase inhibitor
CINOAHEC_01527 1.2e-17 S Protein of unknown function (DUF3813)
CINOAHEC_01529 1.9e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
CINOAHEC_01530 4.5e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
CINOAHEC_01531 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
CINOAHEC_01532 1.5e-22 pilT S Proteolipid membrane potential modulator
CINOAHEC_01533 4.7e-271 yitY C D-arabinono-1,4-lactone oxidase
CINOAHEC_01534 1.7e-88 norB G Major Facilitator Superfamily
CINOAHEC_01535 3.5e-199 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CINOAHEC_01536 5.9e-230 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CINOAHEC_01537 1.6e-135 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
CINOAHEC_01538 2.7e-216 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
CINOAHEC_01539 9.7e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
CINOAHEC_01540 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
CINOAHEC_01541 3.8e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CINOAHEC_01542 9.5e-28 yjzC S YjzC-like protein
CINOAHEC_01543 2.3e-16 yjzD S Protein of unknown function (DUF2929)
CINOAHEC_01544 6.2e-142 yjaU I carboxylic ester hydrolase activity
CINOAHEC_01545 1.8e-101 yjaV
CINOAHEC_01546 2.5e-183 med S Transcriptional activator protein med
CINOAHEC_01547 7.3e-26 comZ S ComZ
CINOAHEC_01548 2.7e-22 yjzB
CINOAHEC_01549 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CINOAHEC_01550 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CINOAHEC_01551 7.8e-151 yjaZ O Zn-dependent protease
CINOAHEC_01552 1.8e-184 appD P Belongs to the ABC transporter superfamily
CINOAHEC_01553 6.5e-187 appF E Belongs to the ABC transporter superfamily
CINOAHEC_01554 1.4e-250 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
CINOAHEC_01555 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CINOAHEC_01556 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CINOAHEC_01557 5e-147 yjbA S Belongs to the UPF0736 family
CINOAHEC_01558 2.3e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
CINOAHEC_01559 0.0 oppA E ABC transporter substrate-binding protein
CINOAHEC_01560 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CINOAHEC_01561 1e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CINOAHEC_01562 3.4e-197 oppD P Belongs to the ABC transporter superfamily
CINOAHEC_01563 5.5e-172 oppF E Belongs to the ABC transporter superfamily
CINOAHEC_01564 5.4e-210 yjbB EGP Major Facilitator Superfamily
CINOAHEC_01565 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CINOAHEC_01566 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
CINOAHEC_01567 6e-112 yjbE P Integral membrane protein TerC family
CINOAHEC_01568 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
CINOAHEC_01569 2.3e-223 yjbF S Competence protein
CINOAHEC_01570 0.0 pepF E oligoendopeptidase F
CINOAHEC_01571 1.8e-20
CINOAHEC_01573 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
CINOAHEC_01574 3.7e-72 yjbI S Bacterial-like globin
CINOAHEC_01575 2.2e-83 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
CINOAHEC_01576 1.2e-100 yjbK S protein conserved in bacteria
CINOAHEC_01577 6e-61 yjbL S Belongs to the UPF0738 family
CINOAHEC_01578 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
CINOAHEC_01579 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CINOAHEC_01580 9.9e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CINOAHEC_01581 7.3e-127 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
CINOAHEC_01582 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
CINOAHEC_01583 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CINOAHEC_01584 1.4e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
CINOAHEC_01585 3.6e-218 thiO 1.4.3.19 E Glycine oxidase
CINOAHEC_01586 3e-30 thiS H thiamine diphosphate biosynthetic process
CINOAHEC_01587 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
CINOAHEC_01588 6e-188 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
CINOAHEC_01589 5.3e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
CINOAHEC_01590 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
CINOAHEC_01591 3e-50 yjbX S Spore coat protein
CINOAHEC_01592 5.2e-83 cotZ S Spore coat protein
CINOAHEC_01593 3.4e-96 cotY S Spore coat protein Z
CINOAHEC_01594 6.4e-77 cotX S Spore Coat Protein X and V domain
CINOAHEC_01595 3e-32 cotW
CINOAHEC_01596 4.2e-49 cotV S Spore Coat Protein X and V domain
CINOAHEC_01597 4.3e-56 yjcA S Protein of unknown function (DUF1360)
CINOAHEC_01600 2.9e-38 spoVIF S Stage VI sporulation protein F
CINOAHEC_01601 0.0 yjcD 3.6.4.12 L DNA helicase
CINOAHEC_01602 1.7e-38
CINOAHEC_01603 3.3e-71 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CINOAHEC_01604 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
CINOAHEC_01605 7e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
CINOAHEC_01606 3.2e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
CINOAHEC_01607 9.4e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
CINOAHEC_01608 2.9e-96 rimJ 2.3.1.128 J Alanine acetyltransferase
CINOAHEC_01609 1.1e-212 yjcL S Protein of unknown function (DUF819)
CINOAHEC_01611 1.7e-48
CINOAHEC_01612 6.3e-220 yobL S Bacterial EndoU nuclease
CINOAHEC_01614 3.7e-30 KLT Protein tyrosine kinase
CINOAHEC_01615 1.9e-36
CINOAHEC_01616 9e-19
CINOAHEC_01618 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
CINOAHEC_01619 2e-140 IQ Enoyl-(Acyl carrier protein) reductase
CINOAHEC_01621 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
CINOAHEC_01622 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
CINOAHEC_01623 2.1e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
CINOAHEC_01624 1.9e-47 yjdF S Protein of unknown function (DUF2992)
CINOAHEC_01625 1e-90 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
CINOAHEC_01627 1.4e-78 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CINOAHEC_01628 4.2e-29 S Domain of unknown function (DUF4177)
CINOAHEC_01629 1e-48 yjdJ S Domain of unknown function (DUF4306)
CINOAHEC_01630 7.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
CINOAHEC_01632 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
CINOAHEC_01633 3e-81 S Protein of unknown function (DUF2690)
CINOAHEC_01634 2.3e-20 yjfB S Putative motility protein
CINOAHEC_01635 3.4e-166 yjfC O Predicted Zn-dependent protease (DUF2268)
CINOAHEC_01636 1.2e-45 T PhoQ Sensor
CINOAHEC_01637 1.3e-102 yjgB S Domain of unknown function (DUF4309)
CINOAHEC_01638 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
CINOAHEC_01639 1.6e-94 yjgD S Protein of unknown function (DUF1641)
CINOAHEC_01641 2.3e-113 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
CINOAHEC_01643 2.2e-221 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
CINOAHEC_01644 1.6e-216 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
CINOAHEC_01645 8.2e-30
CINOAHEC_01646 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
CINOAHEC_01647 1.9e-122 ybbM S transport system, permease component
CINOAHEC_01648 5.4e-133 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
CINOAHEC_01649 1.9e-175 yjlA EG Putative multidrug resistance efflux transporter
CINOAHEC_01650 4.9e-90 yjlB S Cupin domain
CINOAHEC_01651 7.1e-66 yjlC S Protein of unknown function (DUF1641)
CINOAHEC_01652 2.9e-218 yjlD 1.6.99.3 C NADH dehydrogenase
CINOAHEC_01653 1e-278 uxaC 5.3.1.12 G glucuronate isomerase
CINOAHEC_01654 9.2e-248 yjmB G symporter YjmB
CINOAHEC_01655 1.2e-188 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
CINOAHEC_01656 8.2e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
CINOAHEC_01657 1.4e-214 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
CINOAHEC_01658 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CINOAHEC_01659 1.6e-225 exuT G Sugar (and other) transporter
CINOAHEC_01660 2.3e-184 exuR K transcriptional
CINOAHEC_01661 8.1e-287 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
CINOAHEC_01662 3.5e-285 uxaA 4.2.1.7, 4.4.1.24 G Altronate
CINOAHEC_01663 7.4e-130 MA20_18170 S membrane transporter protein
CINOAHEC_01664 8e-79 yjoA S DinB family
CINOAHEC_01665 4e-245 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
CINOAHEC_01666 1e-212 S response regulator aspartate phosphatase
CINOAHEC_01668 6.3e-41 S YCII-related domain
CINOAHEC_01669 9.1e-170 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
CINOAHEC_01670 6.8e-60 yjqA S Bacterial PH domain
CINOAHEC_01671 2.1e-111 yjqB S Pfam:DUF867
CINOAHEC_01672 4.4e-160 ydbD P Catalase
CINOAHEC_01673 1e-110 xkdA E IrrE N-terminal-like domain
CINOAHEC_01674 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
CINOAHEC_01676 2.3e-156 xkdB K sequence-specific DNA binding
CINOAHEC_01677 9.2e-118 xkdC L Bacterial dnaA protein
CINOAHEC_01680 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
CINOAHEC_01681 2.2e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
CINOAHEC_01682 1.3e-137 xtmA L phage terminase small subunit
CINOAHEC_01683 1.2e-252 xtmB S phage terminase, large subunit
CINOAHEC_01684 4.6e-285 yqbA S portal protein
CINOAHEC_01685 3.5e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
CINOAHEC_01686 5.8e-169 xkdG S Phage capsid family
CINOAHEC_01687 1.5e-62 yqbG S Protein of unknown function (DUF3199)
CINOAHEC_01688 3.3e-64 yqbH S Domain of unknown function (DUF3599)
CINOAHEC_01689 8.4e-87 xkdI S Bacteriophage HK97-gp10, putative tail-component
CINOAHEC_01690 1.9e-77 xkdJ
CINOAHEC_01691 2.5e-256 xkdK S Phage tail sheath C-terminal domain
CINOAHEC_01692 6.1e-76 xkdM S Phage tail tube protein
CINOAHEC_01693 1e-75 S Phage XkdN-like tail assembly chaperone protein, TAC
CINOAHEC_01694 3.4e-263 xkdO L Transglycosylase SLT domain
CINOAHEC_01695 3.7e-122 xkdP S Lysin motif
CINOAHEC_01696 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
CINOAHEC_01697 6.1e-39 xkdR S Protein of unknown function (DUF2577)
CINOAHEC_01698 2.4e-69 xkdS S Protein of unknown function (DUF2634)
CINOAHEC_01699 1.1e-189 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
CINOAHEC_01700 5.8e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
CINOAHEC_01701 8.7e-41
CINOAHEC_01702 1.5e-260
CINOAHEC_01703 2.6e-55 xkdW S XkdW protein
CINOAHEC_01704 3.8e-23 xkdX
CINOAHEC_01705 4.4e-152 xepA
CINOAHEC_01706 2.8e-39 xhlA S Haemolysin XhlA
CINOAHEC_01707 9.3e-40 xhlB S SPP1 phage holin
CINOAHEC_01708 1.2e-160 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
CINOAHEC_01710 1.5e-22 spoIISB S Stage II sporulation protein SB
CINOAHEC_01711 4e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
CINOAHEC_01712 7.6e-175 pit P phosphate transporter
CINOAHEC_01713 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
CINOAHEC_01714 1.2e-239 steT E amino acid
CINOAHEC_01715 1e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
CINOAHEC_01716 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CINOAHEC_01717 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
CINOAHEC_01719 8.4e-209 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CINOAHEC_01720 4.5e-133 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
CINOAHEC_01721 5.1e-153 dppA E D-aminopeptidase
CINOAHEC_01722 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CINOAHEC_01723 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CINOAHEC_01724 6.6e-187 dppD P Belongs to the ABC transporter superfamily
CINOAHEC_01725 0.0 dppE E ABC transporter substrate-binding protein
CINOAHEC_01727 8.1e-179 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
CINOAHEC_01728 5.2e-201 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
CINOAHEC_01729 5.3e-172 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
CINOAHEC_01730 2.2e-187 ykfD E Belongs to the ABC transporter superfamily
CINOAHEC_01731 5.3e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
CINOAHEC_01732 2e-160 ykgA E Amidinotransferase
CINOAHEC_01733 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
CINOAHEC_01734 9.9e-222 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CINOAHEC_01735 2.7e-129 ykjA S Protein of unknown function (DUF421)
CINOAHEC_01736 3.9e-98 ykkA S Protein of unknown function (DUF664)
CINOAHEC_01737 1.1e-97 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
CINOAHEC_01738 3.5e-55 ykkC P Multidrug resistance protein
CINOAHEC_01739 7e-50 ykkD P Multidrug resistance protein
CINOAHEC_01740 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
CINOAHEC_01741 3.3e-200 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CINOAHEC_01742 6.9e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CINOAHEC_01743 1.3e-70 ohrA O Organic hydroperoxide resistance protein
CINOAHEC_01744 4.4e-74 ohrR K COG1846 Transcriptional regulators
CINOAHEC_01745 1.4e-71 ohrB O Organic hydroperoxide resistance protein
CINOAHEC_01746 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
CINOAHEC_01747 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CINOAHEC_01748 1.5e-175 isp O Belongs to the peptidase S8 family
CINOAHEC_01749 2.4e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CINOAHEC_01750 8.4e-134 ykoC P Cobalt transport protein
CINOAHEC_01751 1e-306 P ABC transporter, ATP-binding protein
CINOAHEC_01752 2.6e-98 ykoE S ABC-type cobalt transport system, permease component
CINOAHEC_01753 6.9e-107 ykoF S YKOF-related Family
CINOAHEC_01754 3.9e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CINOAHEC_01755 1.1e-240 ykoH 2.7.13.3 T Histidine kinase
CINOAHEC_01756 2.1e-112 ykoI S Peptidase propeptide and YPEB domain
CINOAHEC_01757 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
CINOAHEC_01760 2.2e-222 mgtE P Acts as a magnesium transporter
CINOAHEC_01761 1.4e-53 tnrA K transcriptional
CINOAHEC_01762 5.9e-18
CINOAHEC_01763 6.9e-26 ykoL
CINOAHEC_01764 1.3e-81 mhqR K transcriptional
CINOAHEC_01765 8.9e-217 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
CINOAHEC_01766 3.7e-99 ykoP G polysaccharide deacetylase
CINOAHEC_01767 2.1e-154 ykoQ S Calcineurin-like phosphoesterase superfamily domain
CINOAHEC_01768 0.0 ykoS
CINOAHEC_01769 2.1e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
CINOAHEC_01770 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
CINOAHEC_01771 1e-159 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CINOAHEC_01772 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
CINOAHEC_01773 2.7e-109 ykoX S membrane-associated protein
CINOAHEC_01774 6e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
CINOAHEC_01775 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CINOAHEC_01776 4.8e-117 rsgI S Anti-sigma factor N-terminus
CINOAHEC_01777 1.9e-26 sspD S small acid-soluble spore protein
CINOAHEC_01778 1.9e-124 ykrK S Domain of unknown function (DUF1836)
CINOAHEC_01779 1.3e-154 htpX O Belongs to the peptidase M48B family
CINOAHEC_01780 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
CINOAHEC_01781 1.2e-10 ydfR S Protein of unknown function (DUF421)
CINOAHEC_01782 4.1e-18 ykzE
CINOAHEC_01783 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
CINOAHEC_01784 0.0 kinE 2.7.13.3 T Histidine kinase
CINOAHEC_01785 2.7e-88 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CINOAHEC_01787 3.1e-195 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CINOAHEC_01788 7e-228 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CINOAHEC_01789 1.7e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
CINOAHEC_01790 2.6e-230 mtnE 2.6.1.83 E Aminotransferase
CINOAHEC_01791 4.5e-230 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
CINOAHEC_01792 3.2e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
CINOAHEC_01793 3.6e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
CINOAHEC_01794 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CINOAHEC_01795 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
CINOAHEC_01796 6.4e-09 S Spo0E like sporulation regulatory protein
CINOAHEC_01797 5.2e-64 eag
CINOAHEC_01798 4.8e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
CINOAHEC_01799 1.3e-75 ykvE K transcriptional
CINOAHEC_01800 2.5e-125 motB N Flagellar motor protein
CINOAHEC_01801 1e-137 motA N flagellar motor
CINOAHEC_01802 0.0 clpE O Belongs to the ClpA ClpB family
CINOAHEC_01803 2.6e-178 ykvI S membrane
CINOAHEC_01804 9.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CINOAHEC_01805 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
CINOAHEC_01806 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
CINOAHEC_01807 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CINOAHEC_01808 3.8e-60 ykvN K HxlR-like helix-turn-helix
CINOAHEC_01809 5.3e-133 IQ Enoyl-(Acyl carrier protein) reductase
CINOAHEC_01810 1.9e-214 ykvP 3.5.1.28 M Glycosyl transferases group 1
CINOAHEC_01811 6.2e-32 3.5.1.104 M LysM domain
CINOAHEC_01812 6.4e-160 G Glycosyl hydrolases family 18
CINOAHEC_01813 5.6e-46 ykvR S Protein of unknown function (DUF3219)
CINOAHEC_01814 6e-25 ykvS S protein conserved in bacteria
CINOAHEC_01815 2.8e-28
CINOAHEC_01816 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
CINOAHEC_01817 2.9e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CINOAHEC_01818 1.6e-88 stoA CO thiol-disulfide
CINOAHEC_01819 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
CINOAHEC_01820 1e-09
CINOAHEC_01821 1.3e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
CINOAHEC_01822 8.3e-179 ykvZ 5.1.1.1 K Transcriptional regulator
CINOAHEC_01824 7.6e-128 glcT K antiterminator
CINOAHEC_01825 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CINOAHEC_01826 2.1e-39 ptsH G phosphocarrier protein HPr
CINOAHEC_01827 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CINOAHEC_01828 7.2e-39 splA S Transcriptional regulator
CINOAHEC_01829 1.3e-201 splB 4.1.99.14 L Spore photoproduct lyase
CINOAHEC_01830 1.1e-129 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CINOAHEC_01831 1.1e-246 mcpC NT chemotaxis protein
CINOAHEC_01832 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
CINOAHEC_01833 5.7e-122 ykwD J protein with SCP PR1 domains
CINOAHEC_01834 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
CINOAHEC_01835 0.0 pilS 2.7.13.3 T Histidine kinase
CINOAHEC_01836 6.3e-221 patA 2.6.1.1 E Aminotransferase
CINOAHEC_01837 2.2e-15
CINOAHEC_01838 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
CINOAHEC_01839 1.7e-84 ykyB S YkyB-like protein
CINOAHEC_01840 1.6e-238 ykuC EGP Major facilitator Superfamily
CINOAHEC_01841 1.8e-87 ykuD S protein conserved in bacteria
CINOAHEC_01842 9.4e-166 ykuE S Metallophosphoesterase
CINOAHEC_01843 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CINOAHEC_01844 5.2e-234 ykuI T Diguanylate phosphodiesterase
CINOAHEC_01845 3.9e-37 ykuJ S protein conserved in bacteria
CINOAHEC_01846 4.4e-94 ykuK S Ribonuclease H-like
CINOAHEC_01847 3.9e-27 ykzF S Antirepressor AbbA
CINOAHEC_01848 1.6e-76 ykuL S CBS domain
CINOAHEC_01849 3.5e-168 ccpC K Transcriptional regulator
CINOAHEC_01850 3.7e-87 fld C Flavodoxin domain
CINOAHEC_01851 3.2e-177 ykuO
CINOAHEC_01852 4.2e-80 fld C Flavodoxin
CINOAHEC_01853 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
CINOAHEC_01854 5.8e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
CINOAHEC_01855 9e-37 ykuS S Belongs to the UPF0180 family
CINOAHEC_01856 8.8e-142 ykuT M Mechanosensitive ion channel
CINOAHEC_01857 3.9e-101 ykuU O Alkyl hydroperoxide reductase
CINOAHEC_01858 6.3e-81 ykuV CO thiol-disulfide
CINOAHEC_01859 1.5e-93 rok K Repressor of ComK
CINOAHEC_01860 4.9e-147 yknT
CINOAHEC_01861 4.3e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
CINOAHEC_01862 2.9e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
CINOAHEC_01863 2.6e-244 moeA 2.10.1.1 H molybdopterin
CINOAHEC_01864 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
CINOAHEC_01865 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
CINOAHEC_01866 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CINOAHEC_01867 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
CINOAHEC_01868 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
CINOAHEC_01869 1.1e-116 yknW S Yip1 domain
CINOAHEC_01870 3.3e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CINOAHEC_01871 2.5e-124 macB V ABC transporter, ATP-binding protein
CINOAHEC_01872 7.3e-209 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
CINOAHEC_01873 3.1e-136 fruR K Transcriptional regulator
CINOAHEC_01874 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
CINOAHEC_01875 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
CINOAHEC_01876 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
CINOAHEC_01877 8.1e-39 ykoA
CINOAHEC_01878 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
CINOAHEC_01879 1.4e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CINOAHEC_01880 4.5e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
CINOAHEC_01881 1.1e-12 S Uncharacterized protein YkpC
CINOAHEC_01882 7.7e-183 mreB D Rod-share determining protein MreBH
CINOAHEC_01883 1.5e-43 abrB K of stationary sporulation gene expression
CINOAHEC_01884 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
CINOAHEC_01885 1.2e-157 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
CINOAHEC_01886 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
CINOAHEC_01887 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CINOAHEC_01888 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CINOAHEC_01889 8.2e-31 ykzG S Belongs to the UPF0356 family
CINOAHEC_01890 1.6e-146 ykrA S hydrolases of the HAD superfamily
CINOAHEC_01891 8.9e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CINOAHEC_01893 4.6e-109 recN L Putative cell-wall binding lipoprotein
CINOAHEC_01894 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
CINOAHEC_01895 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
CINOAHEC_01896 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CINOAHEC_01897 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
CINOAHEC_01898 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
CINOAHEC_01899 2.2e-276 speA 4.1.1.19 E Arginine
CINOAHEC_01900 1.6e-42 yktA S Belongs to the UPF0223 family
CINOAHEC_01901 2.3e-116 yktB S Belongs to the UPF0637 family
CINOAHEC_01902 7.1e-26 ykzI
CINOAHEC_01903 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
CINOAHEC_01904 5.8e-77 ykzC S Acetyltransferase (GNAT) family
CINOAHEC_01905 4.6e-171 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CINOAHEC_01906 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
CINOAHEC_01907 0.0 ylaA
CINOAHEC_01908 1.9e-40 ylaB
CINOAHEC_01909 2.5e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
CINOAHEC_01910 3.5e-11 sigC S Putative zinc-finger
CINOAHEC_01911 3.8e-36 ylaE
CINOAHEC_01912 8.2e-22 S Family of unknown function (DUF5325)
CINOAHEC_01913 0.0 typA T GTP-binding protein TypA
CINOAHEC_01914 4.2e-47 ylaH S YlaH-like protein
CINOAHEC_01915 2.5e-32 ylaI S protein conserved in bacteria
CINOAHEC_01916 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
CINOAHEC_01917 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
CINOAHEC_01918 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CINOAHEC_01919 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
CINOAHEC_01920 8.7e-44 ylaN S Belongs to the UPF0358 family
CINOAHEC_01921 1.9e-212 ftsW D Belongs to the SEDS family
CINOAHEC_01922 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CINOAHEC_01923 6.5e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
CINOAHEC_01924 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
CINOAHEC_01925 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
CINOAHEC_01926 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CINOAHEC_01927 2.8e-111 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
CINOAHEC_01928 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
CINOAHEC_01929 1.5e-166 ctaG S cytochrome c oxidase
CINOAHEC_01930 7e-62 ylbA S YugN-like family
CINOAHEC_01931 2.6e-74 ylbB T COG0517 FOG CBS domain
CINOAHEC_01932 1.3e-199 ylbC S protein with SCP PR1 domains
CINOAHEC_01933 4.1e-63 ylbD S Putative coat protein
CINOAHEC_01934 6.7e-37 ylbE S YlbE-like protein
CINOAHEC_01935 1.8e-75 ylbF S Belongs to the UPF0342 family
CINOAHEC_01936 3.7e-38 ylbG S UPF0298 protein
CINOAHEC_01937 3e-96 rsmD 2.1.1.171 L Methyltransferase
CINOAHEC_01938 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CINOAHEC_01939 1.1e-220 ylbJ S Sporulation integral membrane protein YlbJ
CINOAHEC_01940 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
CINOAHEC_01941 6.8e-187 ylbL T Belongs to the peptidase S16 family
CINOAHEC_01942 3.2e-231 ylbM S Belongs to the UPF0348 family
CINOAHEC_01944 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
CINOAHEC_01945 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
CINOAHEC_01946 9.1e-72 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
CINOAHEC_01947 1.5e-88 ylbP K n-acetyltransferase
CINOAHEC_01948 4e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CINOAHEC_01949 2.1e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CINOAHEC_01950 2.9e-78 mraZ K Belongs to the MraZ family
CINOAHEC_01951 1.6e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
CINOAHEC_01952 3.7e-44 ftsL D Essential cell division protein
CINOAHEC_01953 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
CINOAHEC_01954 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
CINOAHEC_01955 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CINOAHEC_01956 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CINOAHEC_01957 8.5e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CINOAHEC_01958 5.7e-186 spoVE D Belongs to the SEDS family
CINOAHEC_01959 1.1e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CINOAHEC_01960 5.3e-167 murB 1.3.1.98 M cell wall formation
CINOAHEC_01961 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
CINOAHEC_01962 4.1e-103 ylxW S protein conserved in bacteria
CINOAHEC_01963 1.8e-91 ylxX S protein conserved in bacteria
CINOAHEC_01964 6.2e-58 sbp S small basic protein
CINOAHEC_01965 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
CINOAHEC_01966 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CINOAHEC_01967 0.0 bpr O COG1404 Subtilisin-like serine proteases
CINOAHEC_01968 2.8e-171 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
CINOAHEC_01969 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CINOAHEC_01970 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CINOAHEC_01971 3.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
CINOAHEC_01972 1.2e-249 argE 3.5.1.16 E Acetylornithine deacetylase
CINOAHEC_01973 2.4e-37 ylmC S sporulation protein
CINOAHEC_01974 2.3e-156 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
CINOAHEC_01975 2.5e-124 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CINOAHEC_01976 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
CINOAHEC_01977 1.3e-39 yggT S membrane
CINOAHEC_01978 2e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
CINOAHEC_01979 2.6e-67 divIVA D Cell division initiation protein
CINOAHEC_01980 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CINOAHEC_01981 1.3e-63 dksA T COG1734 DnaK suppressor protein
CINOAHEC_01982 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CINOAHEC_01983 1.9e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CINOAHEC_01984 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CINOAHEC_01985 1.3e-230 pyrP F Xanthine uracil
CINOAHEC_01986 1.5e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
CINOAHEC_01987 9.2e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
CINOAHEC_01988 4.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
CINOAHEC_01989 0.0 carB 6.3.5.5 F Belongs to the CarB family
CINOAHEC_01990 1.2e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
CINOAHEC_01991 1.3e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
CINOAHEC_01992 3.3e-124 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
CINOAHEC_01993 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CINOAHEC_01995 2.2e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
CINOAHEC_01996 5.4e-179 cysP P phosphate transporter
CINOAHEC_01997 5e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
CINOAHEC_01998 6.2e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
CINOAHEC_01999 4.1e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
CINOAHEC_02000 4.9e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
CINOAHEC_02001 1.3e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
CINOAHEC_02002 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
CINOAHEC_02003 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
CINOAHEC_02004 2.4e-156 yloC S stress-induced protein
CINOAHEC_02005 1.5e-40 ylzA S Belongs to the UPF0296 family
CINOAHEC_02006 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
CINOAHEC_02007 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
CINOAHEC_02008 1.4e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CINOAHEC_02009 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CINOAHEC_02010 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CINOAHEC_02011 7.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CINOAHEC_02012 2.4e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CINOAHEC_02013 1.4e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CINOAHEC_02014 1.6e-140 stp 3.1.3.16 T phosphatase
CINOAHEC_02015 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
CINOAHEC_02016 3.3e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
CINOAHEC_02017 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
CINOAHEC_02018 6.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
CINOAHEC_02019 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
CINOAHEC_02020 5.5e-59 asp S protein conserved in bacteria
CINOAHEC_02021 4.3e-300 yloV S kinase related to dihydroxyacetone kinase
CINOAHEC_02022 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
CINOAHEC_02023 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
CINOAHEC_02024 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CINOAHEC_02025 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
CINOAHEC_02026 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
CINOAHEC_02027 7.7e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
CINOAHEC_02028 6.1e-129 IQ reductase
CINOAHEC_02029 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
CINOAHEC_02030 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
CINOAHEC_02031 0.0 smc D Required for chromosome condensation and partitioning
CINOAHEC_02032 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CINOAHEC_02033 2.9e-87
CINOAHEC_02034 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CINOAHEC_02035 6e-236 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CINOAHEC_02036 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
CINOAHEC_02037 4.5e-36 ylqC S Belongs to the UPF0109 family
CINOAHEC_02038 1.4e-60 ylqD S YlqD protein
CINOAHEC_02039 2.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CINOAHEC_02040 2.1e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
CINOAHEC_02041 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
CINOAHEC_02042 1.6e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CINOAHEC_02043 1e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CINOAHEC_02044 6.1e-289 ylqG
CINOAHEC_02045 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
CINOAHEC_02046 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
CINOAHEC_02047 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CINOAHEC_02048 4.7e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
CINOAHEC_02049 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CINOAHEC_02050 1.6e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CINOAHEC_02051 2.5e-169 xerC L tyrosine recombinase XerC
CINOAHEC_02052 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CINOAHEC_02053 2.2e-241 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CINOAHEC_02054 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CINOAHEC_02055 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
CINOAHEC_02056 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
CINOAHEC_02057 1.9e-31 fliE N Flagellar hook-basal body
CINOAHEC_02058 2.6e-254 fliF N The M ring may be actively involved in energy transduction
CINOAHEC_02059 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
CINOAHEC_02060 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
CINOAHEC_02061 9.4e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
CINOAHEC_02062 1.5e-69 fliJ N Flagellar biosynthesis chaperone
CINOAHEC_02063 7.7e-37 ylxF S MgtE intracellular N domain
CINOAHEC_02064 3.6e-202 fliK N Flagellar hook-length control protein
CINOAHEC_02065 1.7e-72 flgD N Flagellar basal body rod modification protein
CINOAHEC_02066 8.2e-140 flgG N Flagellar basal body rod
CINOAHEC_02067 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
CINOAHEC_02068 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
CINOAHEC_02069 7.7e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CINOAHEC_02070 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
CINOAHEC_02071 1.6e-96 fliZ N Flagellar biosynthesis protein, FliO
CINOAHEC_02072 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
CINOAHEC_02073 2.2e-36 fliQ N Role in flagellar biosynthesis
CINOAHEC_02074 3.6e-132 fliR N Flagellar biosynthetic protein FliR
CINOAHEC_02075 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CINOAHEC_02076 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CINOAHEC_02077 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
CINOAHEC_02078 7.5e-158 flhG D Belongs to the ParA family
CINOAHEC_02079 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
CINOAHEC_02080 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
CINOAHEC_02081 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
CINOAHEC_02082 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
CINOAHEC_02083 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
CINOAHEC_02084 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CINOAHEC_02085 4.3e-78 ylxL
CINOAHEC_02086 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
CINOAHEC_02087 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CINOAHEC_02088 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
CINOAHEC_02089 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
CINOAHEC_02090 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CINOAHEC_02091 2.7e-138 cdsA 2.7.7.41 S Belongs to the CDS family
CINOAHEC_02092 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
CINOAHEC_02093 7.7e-233 rasP M zinc metalloprotease
CINOAHEC_02094 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
CINOAHEC_02095 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CINOAHEC_02096 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
CINOAHEC_02097 1.1e-203 nusA K Participates in both transcription termination and antitermination
CINOAHEC_02098 4e-33 ylxR K nucleic-acid-binding protein implicated in transcription termination
CINOAHEC_02099 3.1e-47 ylxQ J ribosomal protein
CINOAHEC_02100 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CINOAHEC_02101 3.9e-44 ylxP S protein conserved in bacteria
CINOAHEC_02102 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CINOAHEC_02103 1.5e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CINOAHEC_02104 2e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
CINOAHEC_02105 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CINOAHEC_02106 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
CINOAHEC_02107 9.8e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
CINOAHEC_02108 4.4e-233 pepR S Belongs to the peptidase M16 family
CINOAHEC_02109 2.6e-42 ymxH S YlmC YmxH family
CINOAHEC_02110 6.6e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
CINOAHEC_02111 2.2e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
CINOAHEC_02112 2.1e-191 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CINOAHEC_02113 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
CINOAHEC_02114 5.2e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CINOAHEC_02115 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CINOAHEC_02116 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
CINOAHEC_02117 4.4e-32 S YlzJ-like protein
CINOAHEC_02118 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
CINOAHEC_02119 1.4e-133 ymfC K Transcriptional regulator
CINOAHEC_02120 3.8e-205 ymfD EGP Major facilitator Superfamily
CINOAHEC_02121 2e-233 ymfF S Peptidase M16
CINOAHEC_02122 4.1e-242 ymfH S zinc protease
CINOAHEC_02123 7.8e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
CINOAHEC_02124 1.8e-40 ymfJ S Protein of unknown function (DUF3243)
CINOAHEC_02125 2.7e-143 ymfK S Protein of unknown function (DUF3388)
CINOAHEC_02126 1.9e-124 ymfM S protein conserved in bacteria
CINOAHEC_02127 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CINOAHEC_02128 9.6e-236 cinA 3.5.1.42 S Belongs to the CinA family
CINOAHEC_02129 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CINOAHEC_02130 9.7e-214 pbpX V Beta-lactamase
CINOAHEC_02131 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
CINOAHEC_02132 1.9e-152 ymdB S protein conserved in bacteria
CINOAHEC_02133 1.2e-36 spoVS S Stage V sporulation protein S
CINOAHEC_02134 2.1e-196 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
CINOAHEC_02135 2.3e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
CINOAHEC_02136 5e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CINOAHEC_02137 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
CINOAHEC_02138 2.2e-88 cotE S Spore coat protein
CINOAHEC_02139 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CINOAHEC_02140 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CINOAHEC_02141 4.4e-69 S Regulatory protein YrvL
CINOAHEC_02143 1.1e-95 ymcC S Membrane
CINOAHEC_02144 2.4e-107 pksA K Transcriptional regulator
CINOAHEC_02145 6.3e-125 pksB 3.1.2.6 S Polyketide biosynthesis
CINOAHEC_02146 1.2e-160 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
CINOAHEC_02148 1.6e-182 pksD Q Acyl transferase domain
CINOAHEC_02149 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
CINOAHEC_02150 1.4e-37 acpK IQ Phosphopantetheine attachment site
CINOAHEC_02151 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CINOAHEC_02152 7.4e-244 pksG 2.3.3.10 I synthase
CINOAHEC_02153 2.7e-140 pksH 4.2.1.18 I enoyl-CoA hydratase
CINOAHEC_02154 1e-136 pksI I Belongs to the enoyl-CoA hydratase isomerase family
CINOAHEC_02155 0.0 rhiB IQ polyketide synthase
CINOAHEC_02156 0.0 pfaA Q Polyketide synthase of type I
CINOAHEC_02157 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
CINOAHEC_02158 0.0 dhbF IQ polyketide synthase
CINOAHEC_02159 0.0 pks13 HQ Beta-ketoacyl synthase
CINOAHEC_02160 1.4e-231 cypA C Cytochrome P450
CINOAHEC_02161 1.7e-60 ymzB
CINOAHEC_02162 6.8e-161 ymaE S Metallo-beta-lactamase superfamily
CINOAHEC_02163 1.8e-248 aprX O Belongs to the peptidase S8 family
CINOAHEC_02164 1.9e-07 K Transcriptional regulator
CINOAHEC_02165 2.1e-126 ymaC S Replication protein
CINOAHEC_02166 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
CINOAHEC_02167 1.4e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
CINOAHEC_02168 9.2e-50 ebrA P Small Multidrug Resistance protein
CINOAHEC_02170 2.1e-46 ymaF S YmaF family
CINOAHEC_02171 3.5e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CINOAHEC_02172 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
CINOAHEC_02173 4.1e-22
CINOAHEC_02174 4.5e-22 ymzA
CINOAHEC_02175 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
CINOAHEC_02176 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CINOAHEC_02177 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CINOAHEC_02178 1e-108 ymaB
CINOAHEC_02179 6.3e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
CINOAHEC_02180 2.4e-97 spoVK O stage V sporulation protein K
CINOAHEC_02182 5.8e-81 yhbS S family acetyltransferase
CINOAHEC_02183 8.7e-106 yokF 3.1.31.1 L RNA catabolic process
CINOAHEC_02184 1e-35
CINOAHEC_02185 1.2e-65 G SMI1-KNR4 cell-wall
CINOAHEC_02186 7.2e-213 UW nuclease activity
CINOAHEC_02187 1.6e-87 yokK S SMI1 / KNR4 family
CINOAHEC_02189 1.3e-40
CINOAHEC_02190 1e-51 S YolD-like protein
CINOAHEC_02191 1.2e-233 S impB/mucB/samB family C-terminal domain
CINOAHEC_02193 7.2e-190 S aspartate phosphatase
CINOAHEC_02194 6.4e-38 S Bacteriophage holin
CINOAHEC_02196 4.1e-182 S N-acetylmuramoyl-L-alanine amidase activity
CINOAHEC_02197 7.6e-162
CINOAHEC_02198 1e-183 M Pectate lyase superfamily protein
CINOAHEC_02199 2.2e-119
CINOAHEC_02200 5.2e-292 S Pfam Transposase IS66
CINOAHEC_02201 8.5e-86 S Phage tail protein
CINOAHEC_02202 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
CINOAHEC_02203 5.8e-110
CINOAHEC_02205 2.2e-22
CINOAHEC_02206 2.2e-190 xerH A Belongs to the 'phage' integrase family
CINOAHEC_02207 2.3e-56
CINOAHEC_02208 2.5e-54
CINOAHEC_02209 4.8e-98 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
CINOAHEC_02210 1.6e-07 S Phage uncharacterised protein (Phage_XkdX)
CINOAHEC_02211 2.1e-08
CINOAHEC_02212 1.5e-35 S Domain of unknown function (DUF2479)
CINOAHEC_02213 1.2e-45
CINOAHEC_02216 3.2e-59
CINOAHEC_02217 1e-72
CINOAHEC_02218 8.8e-79
CINOAHEC_02219 7e-121
CINOAHEC_02221 7.9e-67
CINOAHEC_02222 1.1e-80
CINOAHEC_02223 2.8e-185
CINOAHEC_02224 7.8e-94
CINOAHEC_02225 3.2e-243
CINOAHEC_02226 1.9e-278
CINOAHEC_02227 0.0 gp17a S Terminase-like family
CINOAHEC_02228 1.8e-175
CINOAHEC_02232 4.3e-225 S hydrolase activity
CINOAHEC_02235 5.6e-236
CINOAHEC_02236 9.5e-35 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CINOAHEC_02237 5.8e-94
CINOAHEC_02238 0.0 S RNA-directed RNA polymerase activity
CINOAHEC_02241 6.1e-203
CINOAHEC_02242 5.9e-22 kilA K SOS response
CINOAHEC_02244 3.6e-12 K Helix-turn-helix XRE-family like proteins
CINOAHEC_02253 3.1e-103
CINOAHEC_02258 5.4e-195 L Belongs to the 'phage' integrase family
CINOAHEC_02259 1.1e-261 S DNA-sulfur modification-associated
CINOAHEC_02260 4.6e-177
CINOAHEC_02261 1.1e-33 K Transcriptional regulator
CINOAHEC_02265 6.2e-42
CINOAHEC_02271 4e-266 3.1.3.16, 3.1.4.37 T phosphatase
CINOAHEC_02276 1.5e-94 S Protein of unknown function (DUF1273)
CINOAHEC_02281 6.9e-74
CINOAHEC_02282 7.1e-147 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
CINOAHEC_02283 6.1e-128 yoqW S Belongs to the SOS response-associated peptidase family
CINOAHEC_02285 1e-159
CINOAHEC_02288 5.7e-144 S Pfam:DUF867
CINOAHEC_02289 0.0 M Parallel beta-helix repeats
CINOAHEC_02293 3.6e-155
CINOAHEC_02294 7.6e-180 L AAA domain
CINOAHEC_02295 1.2e-85
CINOAHEC_02296 3.9e-284 3.6.4.12 J DnaB-like helicase C terminal domain
CINOAHEC_02297 3.8e-223 L DNA primase activity
CINOAHEC_02298 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
CINOAHEC_02299 0.0 S Bacterial DNA polymerase III alpha subunit
CINOAHEC_02300 1.7e-123 DR0488 S protein conserved in bacteria
CINOAHEC_02305 1.4e-84 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
CINOAHEC_02306 8.7e-90 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
CINOAHEC_02308 5.1e-146 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
CINOAHEC_02314 3.5e-25 S hydrolase activity
CINOAHEC_02323 3.8e-10 larC 4.99.1.12 FJ Protein conserved in bacteria
CINOAHEC_02328 7.9e-67 S NrdI Flavodoxin like
CINOAHEC_02329 1.8e-114 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CINOAHEC_02330 5.5e-196 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CINOAHEC_02332 8.3e-105 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CINOAHEC_02333 4.5e-86 L HNH endonuclease
CINOAHEC_02334 3.2e-62 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CINOAHEC_02335 1.4e-34 O Glutaredoxin
CINOAHEC_02337 5.4e-51 pth_2 3.1.1.29 S Peptidyl-tRNA hydrolase PTH2
CINOAHEC_02339 1.1e-09
CINOAHEC_02340 3.6e-73 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
CINOAHEC_02345 6e-27
CINOAHEC_02346 9.8e-121 3.1.3.16 L DnaD domain protein
CINOAHEC_02347 2.2e-162 xkdC L IstB-like ATP binding protein
CINOAHEC_02349 9.7e-71 rusA L Endodeoxyribonuclease RusA
CINOAHEC_02350 2.4e-30 yqaO S Phage-like element PBSX protein XtrA
CINOAHEC_02351 4.3e-110 L SacI restriction endonuclease
CINOAHEC_02352 3.4e-147 dcm 2.1.1.37 L C-5 cytosine-specific DNA methylase
CINOAHEC_02353 3.1e-75 L Transposase
CINOAHEC_02356 3e-101 yqaS L DNA packaging
CINOAHEC_02357 2.1e-246 S phage terminase, large subunit
CINOAHEC_02358 6.3e-290 yqbA S portal protein
CINOAHEC_02359 1.4e-151 S Phage Mu protein F like protein
CINOAHEC_02361 8.8e-120 yqbD 2.1.1.72 L Putative phage serine protease XkdF
CINOAHEC_02362 4.6e-166 xkdG S Phage capsid family
CINOAHEC_02363 6.7e-45 S YqbF, hypothetical protein domain
CINOAHEC_02364 4.6e-67 S Protein of unknown function (DUF3199)
CINOAHEC_02365 6.3e-63 yqbH S Domain of unknown function (DUF3599)
CINOAHEC_02366 5.6e-86 S Bacteriophage HK97-gp10, putative tail-component
CINOAHEC_02367 6.6e-75
CINOAHEC_02368 4.6e-25
CINOAHEC_02369 7.4e-253 xkdK S Phage tail sheath C-terminal domain
CINOAHEC_02370 3.9e-75 xkdM S Phage tail tube protein
CINOAHEC_02372 1.8e-67 S Phage XkdN-like tail assembly chaperone protein, TAC
CINOAHEC_02373 0.0 xkdO L Transglycosylase SLT domain
CINOAHEC_02374 9e-114 xkdP S Lysin motif
CINOAHEC_02375 2.4e-181 yqbQ 3.2.1.96 G NLP P60 protein
CINOAHEC_02376 1.8e-38 xkdR S Protein of unknown function (DUF2577)
CINOAHEC_02377 9.6e-71 xkdS S Protein of unknown function (DUF2634)
CINOAHEC_02378 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
CINOAHEC_02379 9.9e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
CINOAHEC_02380 9.6e-40
CINOAHEC_02381 2e-221
CINOAHEC_02382 4.1e-56 xkdW S XkdW protein
CINOAHEC_02383 1.3e-23
CINOAHEC_02384 4.8e-165 xepA
CINOAHEC_02385 2.6e-68 S Bacteriophage holin family
CINOAHEC_02386 1.1e-144 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
CINOAHEC_02388 5e-60
CINOAHEC_02390 5.3e-104 S Suppressor of fused protein (SUFU)
CINOAHEC_02391 3.3e-273 A Pre-toxin TG
CINOAHEC_02392 1.7e-27
CINOAHEC_02394 4.7e-64 S response regulator aspartate phosphatase
CINOAHEC_02395 5.1e-42 S Spore coat protein Z
CINOAHEC_02396 1.1e-40 S Protein of unknown function (DUF3992)
CINOAHEC_02397 3.1e-44
CINOAHEC_02398 5.1e-139 yhfP 1.1.1.1 C Alcohol dehydrogenase GroES-like domain
CINOAHEC_02399 2.7e-63 K BetI-type transcriptional repressor, C-terminal
CINOAHEC_02400 2e-38 piuB S PepSY-associated TM region
CINOAHEC_02401 1.3e-62 piuB S PepSY-associated TM region
CINOAHEC_02402 5.5e-50 piuB S PepSY-associated TM region
CINOAHEC_02403 2.8e-23 S YtkA-like
CINOAHEC_02404 1.1e-152 yqcI S YqcI/YcgG family
CINOAHEC_02405 1.6e-54 arsR K ArsR family transcriptional regulator
CINOAHEC_02406 2.8e-73 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CINOAHEC_02407 6e-183 arsB 1.20.4.1 P Arsenic resistance protein
CINOAHEC_02408 1.8e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
CINOAHEC_02409 9.3e-278 cisA2 L Recombinase
CINOAHEC_02410 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CINOAHEC_02411 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
CINOAHEC_02412 2.3e-133 yqeB
CINOAHEC_02413 1.5e-169 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
CINOAHEC_02414 1.2e-104 yqeD S SNARE associated Golgi protein
CINOAHEC_02415 9.2e-133 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
CINOAHEC_02416 1.2e-140 yqeF E GDSL-like Lipase/Acylhydrolase
CINOAHEC_02418 5.3e-95 yqeG S hydrolase of the HAD superfamily
CINOAHEC_02419 1.2e-213 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
CINOAHEC_02420 2.3e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CINOAHEC_02421 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
CINOAHEC_02422 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CINOAHEC_02423 7.4e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
CINOAHEC_02424 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
CINOAHEC_02425 1.2e-137 yqeM Q Methyltransferase
CINOAHEC_02426 5.1e-145 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CINOAHEC_02427 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
CINOAHEC_02428 1.8e-104 comEB 3.5.4.12 F ComE operon protein 2
CINOAHEC_02429 0.0 comEC S Competence protein ComEC
CINOAHEC_02430 4.1e-15 S YqzM-like protein
CINOAHEC_02431 5.6e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
CINOAHEC_02432 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
CINOAHEC_02433 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CINOAHEC_02434 1.5e-222 spoIIP M stage II sporulation protein P
CINOAHEC_02435 7.2e-53 yqxA S Protein of unknown function (DUF3679)
CINOAHEC_02436 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
CINOAHEC_02437 7e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
CINOAHEC_02438 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
CINOAHEC_02439 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CINOAHEC_02440 0.0 dnaK O Heat shock 70 kDa protein
CINOAHEC_02441 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
CINOAHEC_02442 5.4e-175 prmA J Methylates ribosomal protein L11
CINOAHEC_02443 3.6e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
CINOAHEC_02444 1.8e-259 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
CINOAHEC_02445 8.2e-158 yqeW P COG1283 Na phosphate symporter
CINOAHEC_02446 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
CINOAHEC_02447 2.5e-61 yqeY S Yqey-like protein
CINOAHEC_02448 1e-227 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
CINOAHEC_02449 4.3e-122 yqfA S UPF0365 protein
CINOAHEC_02450 2.4e-21 yqfB
CINOAHEC_02451 2.7e-45 yqfC S sporulation protein YqfC
CINOAHEC_02452 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
CINOAHEC_02453 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
CINOAHEC_02455 0.0 yqfF S membrane-associated HD superfamily hydrolase
CINOAHEC_02456 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CINOAHEC_02457 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
CINOAHEC_02458 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
CINOAHEC_02459 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CINOAHEC_02460 8.4e-19 S YqzL-like protein
CINOAHEC_02461 4.8e-145 recO L Involved in DNA repair and RecF pathway recombination
CINOAHEC_02462 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
CINOAHEC_02463 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
CINOAHEC_02464 4.5e-112 ccpN K CBS domain
CINOAHEC_02465 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
CINOAHEC_02466 1.7e-87 yaiI S Belongs to the UPF0178 family
CINOAHEC_02467 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CINOAHEC_02468 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CINOAHEC_02469 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
CINOAHEC_02470 6.8e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
CINOAHEC_02471 5.6e-211 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CINOAHEC_02472 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CINOAHEC_02473 1.6e-12 yqfQ S YqfQ-like protein
CINOAHEC_02474 1.9e-242 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
CINOAHEC_02475 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CINOAHEC_02476 2.1e-36 yqfT S Protein of unknown function (DUF2624)
CINOAHEC_02477 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
CINOAHEC_02478 4.2e-77 zur P Belongs to the Fur family
CINOAHEC_02479 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
CINOAHEC_02480 2.8e-61 yqfX S membrane
CINOAHEC_02481 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CINOAHEC_02482 8.9e-47 yqfZ M LysM domain
CINOAHEC_02483 5.6e-130 yqgB S Protein of unknown function (DUF1189)
CINOAHEC_02484 4e-73 yqgC S protein conserved in bacteria
CINOAHEC_02485 1.8e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
CINOAHEC_02486 4.3e-231 yqgE EGP Major facilitator superfamily
CINOAHEC_02487 0.0 pbpA 3.4.16.4 M penicillin-binding protein
CINOAHEC_02488 1.7e-149 pstS P Phosphate
CINOAHEC_02489 3.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
CINOAHEC_02490 4.4e-158 pstA P Phosphate transport system permease
CINOAHEC_02491 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CINOAHEC_02492 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CINOAHEC_02493 2.1e-71 yqzC S YceG-like family
CINOAHEC_02494 9.2e-51 yqzD
CINOAHEC_02496 1.1e-200 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
CINOAHEC_02497 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
CINOAHEC_02498 5.1e-104 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CINOAHEC_02499 2.5e-09 yqgO
CINOAHEC_02500 2.8e-261 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
CINOAHEC_02501 3.1e-33 yqgQ S Protein conserved in bacteria
CINOAHEC_02502 3.4e-180 glcK 2.7.1.2 G Glucokinase
CINOAHEC_02503 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
CINOAHEC_02504 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
CINOAHEC_02505 7.4e-197 yqgU
CINOAHEC_02506 1.5e-49 yqgV S Thiamine-binding protein
CINOAHEC_02507 8.9e-23 yqgW S Protein of unknown function (DUF2759)
CINOAHEC_02508 2.1e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
CINOAHEC_02509 1.8e-37 yqgY S Protein of unknown function (DUF2626)
CINOAHEC_02510 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
CINOAHEC_02512 3.2e-150 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CINOAHEC_02513 4.4e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
CINOAHEC_02514 7.2e-175 corA P Mg2 transporter protein
CINOAHEC_02516 1.1e-200 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CINOAHEC_02517 5.1e-174 comGB NU COG1459 Type II secretory pathway, component PulF
CINOAHEC_02518 1.4e-47 comGC U Required for transformation and DNA binding
CINOAHEC_02519 1.2e-68 gspH NU protein transport across the cell outer membrane
CINOAHEC_02520 7.6e-58 comGE
CINOAHEC_02521 3.9e-44 comGF U Putative Competence protein ComGF
CINOAHEC_02522 2.6e-43 S ComG operon protein 7
CINOAHEC_02523 5.2e-26 yqzE S YqzE-like protein
CINOAHEC_02524 7.3e-54 yqzG S Protein of unknown function (DUF3889)
CINOAHEC_02525 9e-112 yqxM
CINOAHEC_02526 2.5e-58 sipW 3.4.21.89 U Signal peptidase
CINOAHEC_02527 4.3e-141 tasA S Cell division protein FtsN
CINOAHEC_02528 1e-54 sinR K transcriptional
CINOAHEC_02529 1.2e-24 sinI S Anti-repressor SinI
CINOAHEC_02530 3.2e-152 yqhG S Bacterial protein YqhG of unknown function
CINOAHEC_02531 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
CINOAHEC_02532 5.3e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
CINOAHEC_02533 4.9e-254 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CINOAHEC_02534 1.4e-286 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CINOAHEC_02535 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
CINOAHEC_02536 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
CINOAHEC_02537 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
CINOAHEC_02538 1.5e-163 yqhO S esterase of the alpha-beta hydrolase superfamily
CINOAHEC_02539 2.2e-61 yqhP
CINOAHEC_02540 3e-173 yqhQ S Protein of unknown function (DUF1385)
CINOAHEC_02541 2.3e-93 yqhR S Conserved membrane protein YqhR
CINOAHEC_02542 5.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
CINOAHEC_02543 5.7e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
CINOAHEC_02544 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CINOAHEC_02545 7.9e-37 yqhV S Protein of unknown function (DUF2619)
CINOAHEC_02546 6.8e-170 spoIIIAA S stage III sporulation protein AA
CINOAHEC_02547 3.2e-84 spoIIIAB S Stage III sporulation protein
CINOAHEC_02548 7.6e-29 spoIIIAC S stage III sporulation protein AC
CINOAHEC_02549 2.3e-58 spoIIIAD S Stage III sporulation protein AD
CINOAHEC_02550 1.3e-197 spoIIIAE S stage III sporulation protein AE
CINOAHEC_02551 6.9e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
CINOAHEC_02552 5e-109 spoIIIAG S stage III sporulation protein AG
CINOAHEC_02553 3.1e-84 spoIIIAH S SpoIIIAH-like protein
CINOAHEC_02554 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
CINOAHEC_02555 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
CINOAHEC_02556 2.1e-67 yqhY S protein conserved in bacteria
CINOAHEC_02557 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CINOAHEC_02558 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CINOAHEC_02559 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CINOAHEC_02560 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CINOAHEC_02561 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
CINOAHEC_02562 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CINOAHEC_02563 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
CINOAHEC_02564 1.7e-78 argR K Regulates arginine biosynthesis genes
CINOAHEC_02565 3.2e-306 recN L May be involved in recombinational repair of damaged DNA
CINOAHEC_02566 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
CINOAHEC_02567 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
CINOAHEC_02569 2.8e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
CINOAHEC_02570 5.9e-27
CINOAHEC_02571 1.7e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
CINOAHEC_02572 3.1e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
CINOAHEC_02573 2.6e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
CINOAHEC_02574 1e-156 hbdA 1.1.1.157 I Dehydrogenase
CINOAHEC_02575 1.8e-212 mmgC I acyl-CoA dehydrogenase
CINOAHEC_02576 8.1e-210 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
CINOAHEC_02577 2.2e-276 prpD 4.2.1.79 S 2-methylcitrate dehydratase
CINOAHEC_02578 3e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CINOAHEC_02579 4e-34 yqzF S Protein of unknown function (DUF2627)
CINOAHEC_02580 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
CINOAHEC_02581 3e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
CINOAHEC_02582 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
CINOAHEC_02583 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
CINOAHEC_02584 3.7e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
CINOAHEC_02585 7.2e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
CINOAHEC_02586 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
CINOAHEC_02587 4.4e-220 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CINOAHEC_02588 2.2e-151 bmrR K helix_turn_helix, mercury resistance
CINOAHEC_02589 7.9e-208 norA EGP Major facilitator Superfamily
CINOAHEC_02590 3.7e-165 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
CINOAHEC_02591 9.3e-77 yqiW S Belongs to the UPF0403 family
CINOAHEC_02592 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
CINOAHEC_02593 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
CINOAHEC_02594 4.5e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
CINOAHEC_02595 3.3e-175 yqjA S Putative aromatic acid exporter C-terminal domain
CINOAHEC_02596 1.4e-98 yqjB S protein conserved in bacteria
CINOAHEC_02598 2.2e-75 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
CINOAHEC_02599 1.8e-289 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
CINOAHEC_02600 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
CINOAHEC_02601 8.9e-141 yqjF S Uncharacterized conserved protein (COG2071)
CINOAHEC_02602 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CINOAHEC_02603 4.5e-24 yqzJ
CINOAHEC_02604 7.3e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CINOAHEC_02605 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CINOAHEC_02606 1.4e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CINOAHEC_02607 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
CINOAHEC_02608 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
CINOAHEC_02609 3.6e-145 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
CINOAHEC_02610 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
CINOAHEC_02611 0.0 rocB E arginine degradation protein
CINOAHEC_02612 5.6e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CINOAHEC_02613 1.8e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
CINOAHEC_02614 5e-142 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
CINOAHEC_02615 7.9e-260 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
CINOAHEC_02616 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
CINOAHEC_02617 8.8e-71 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CINOAHEC_02619 9e-226 yqjV G Major Facilitator Superfamily
CINOAHEC_02621 1.6e-238 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CINOAHEC_02622 9.8e-50 S YolD-like protein
CINOAHEC_02623 1.8e-86 yqjY K acetyltransferase
CINOAHEC_02624 4e-59 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
CINOAHEC_02625 7.5e-194 yqkA K GrpB protein
CINOAHEC_02626 2.8e-54 yqkB S Belongs to the HesB IscA family
CINOAHEC_02627 9.4e-39 yqkC S Protein of unknown function (DUF2552)
CINOAHEC_02628 8.5e-173 yqkD S COG1073 Hydrolases of the alpha beta superfamily
CINOAHEC_02629 3.1e-12 yqkE S Protein of unknown function (DUF3886)
CINOAHEC_02630 6.3e-168 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
CINOAHEC_02632 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
CINOAHEC_02633 1.4e-220 yqxK 3.6.4.12 L DNA helicase
CINOAHEC_02634 4.5e-58 ansR K Transcriptional regulator
CINOAHEC_02635 2.3e-184 ansA 3.5.1.1 EJ L-asparaginase
CINOAHEC_02636 4.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
CINOAHEC_02637 3.1e-235 mleN C Na H antiporter
CINOAHEC_02638 5.5e-242 mleA 1.1.1.38 C malic enzyme
CINOAHEC_02639 2.2e-31 yqkK
CINOAHEC_02640 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
CINOAHEC_02641 3.2e-77 fur P Belongs to the Fur family
CINOAHEC_02642 1.4e-36 S Protein of unknown function (DUF4227)
CINOAHEC_02643 2.6e-166 xerD L recombinase XerD
CINOAHEC_02644 3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
CINOAHEC_02645 2.9e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CINOAHEC_02646 6.3e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
CINOAHEC_02647 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
CINOAHEC_02648 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
CINOAHEC_02649 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CINOAHEC_02650 9.6e-112 spoVAA S Stage V sporulation protein AA
CINOAHEC_02651 1e-67 spoVAB S Stage V sporulation protein AB
CINOAHEC_02652 2.3e-78 spoVAC S stage V sporulation protein AC
CINOAHEC_02653 9e-192 spoVAD I Stage V sporulation protein AD
CINOAHEC_02654 2.2e-57 spoVAEB S stage V sporulation protein
CINOAHEC_02655 1.4e-110 spoVAEA S stage V sporulation protein
CINOAHEC_02656 1.4e-273 spoVAF EG Stage V sporulation protein AF
CINOAHEC_02657 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
CINOAHEC_02658 8.1e-149 ypuA S Secreted protein
CINOAHEC_02659 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CINOAHEC_02664 5.9e-36 S Pfam Transposase IS66
CINOAHEC_02665 1.9e-25 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CINOAHEC_02667 2.5e-32 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
CINOAHEC_02668 1.2e-100 sipT 3.4.21.89 U Belongs to the peptidase S26 family
CINOAHEC_02669 7.8e-55 ypuD
CINOAHEC_02670 2.9e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CINOAHEC_02671 3.3e-115 ribE 2.5.1.9 H Riboflavin synthase
CINOAHEC_02672 1.1e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CINOAHEC_02673 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
CINOAHEC_02674 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CINOAHEC_02675 1.4e-92 ypuF S Domain of unknown function (DUF309)
CINOAHEC_02676 6.4e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CINOAHEC_02677 2.4e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CINOAHEC_02678 7.6e-97 ypuI S Protein of unknown function (DUF3907)
CINOAHEC_02679 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
CINOAHEC_02680 3.5e-103 spmA S Spore maturation protein
CINOAHEC_02681 1.9e-87 spmB S Spore maturation protein
CINOAHEC_02682 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CINOAHEC_02683 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
CINOAHEC_02684 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
CINOAHEC_02685 6.7e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
CINOAHEC_02686 1.2e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CINOAHEC_02687 0.0 resE 2.7.13.3 T Histidine kinase
CINOAHEC_02688 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
CINOAHEC_02689 1.2e-192 rsiX
CINOAHEC_02690 1e-134 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
CINOAHEC_02691 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CINOAHEC_02692 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CINOAHEC_02693 4.7e-41 fer C Ferredoxin
CINOAHEC_02694 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
CINOAHEC_02695 9.2e-286 recQ 3.6.4.12 L DNA helicase
CINOAHEC_02696 1.1e-99 ypbD S metal-dependent membrane protease
CINOAHEC_02697 1.3e-75 ypbE M Lysin motif
CINOAHEC_02698 2.8e-81 ypbF S Protein of unknown function (DUF2663)
CINOAHEC_02699 2.6e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
CINOAHEC_02700 4.5e-103 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
CINOAHEC_02701 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
CINOAHEC_02702 1.4e-173 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
CINOAHEC_02703 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
CINOAHEC_02704 3.3e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
CINOAHEC_02705 2.5e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
CINOAHEC_02706 2e-112 ypfA M Flagellar protein YcgR
CINOAHEC_02707 1.8e-23 S Family of unknown function (DUF5359)
CINOAHEC_02708 2.8e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
CINOAHEC_02709 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
CINOAHEC_02710 3.2e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
CINOAHEC_02711 1e-07 S YpzI-like protein
CINOAHEC_02712 1.3e-102 yphA
CINOAHEC_02713 2.5e-161 seaA S YIEGIA protein
CINOAHEC_02714 7.9e-28 ypzH
CINOAHEC_02715 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
CINOAHEC_02716 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
CINOAHEC_02717 1.6e-18 yphE S Protein of unknown function (DUF2768)
CINOAHEC_02718 6e-137 yphF
CINOAHEC_02719 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CINOAHEC_02720 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CINOAHEC_02721 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
CINOAHEC_02722 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
CINOAHEC_02723 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
CINOAHEC_02724 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
CINOAHEC_02725 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
CINOAHEC_02726 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
CINOAHEC_02727 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
CINOAHEC_02728 1.2e-216 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CINOAHEC_02729 2.2e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CINOAHEC_02730 3e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
CINOAHEC_02731 1.5e-291 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CINOAHEC_02732 1.2e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CINOAHEC_02733 4.3e-114 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
CINOAHEC_02734 6.7e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
CINOAHEC_02735 1.5e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CINOAHEC_02736 4.7e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
CINOAHEC_02737 1.4e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CINOAHEC_02738 2.6e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
CINOAHEC_02739 1.1e-234 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
CINOAHEC_02740 5.9e-233 S COG0457 FOG TPR repeat
CINOAHEC_02741 2.8e-99 ypiB S Belongs to the UPF0302 family
CINOAHEC_02742 4.2e-77 ypiF S Protein of unknown function (DUF2487)
CINOAHEC_02743 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
CINOAHEC_02744 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
CINOAHEC_02745 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
CINOAHEC_02746 7.6e-98 ypjA S membrane
CINOAHEC_02747 1.8e-142 ypjB S sporulation protein
CINOAHEC_02748 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
CINOAHEC_02749 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
CINOAHEC_02750 1.8e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
CINOAHEC_02751 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
CINOAHEC_02752 3.4e-129 bshB1 S proteins, LmbE homologs
CINOAHEC_02753 7.7e-208 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
CINOAHEC_02754 4.3e-217 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CINOAHEC_02755 2.5e-183 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
CINOAHEC_02756 9.2e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
CINOAHEC_02757 8e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CINOAHEC_02758 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CINOAHEC_02759 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
CINOAHEC_02760 6.7e-23 ypmA S Protein of unknown function (DUF4264)
CINOAHEC_02761 3.4e-80 ypmB S protein conserved in bacteria
CINOAHEC_02762 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
CINOAHEC_02763 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
CINOAHEC_02764 1.1e-127 dnaD L DNA replication protein DnaD
CINOAHEC_02765 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CINOAHEC_02766 8.8e-92 ypoC
CINOAHEC_02767 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
CINOAHEC_02768 1e-113 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
CINOAHEC_02769 2e-185 yppC S Protein of unknown function (DUF2515)
CINOAHEC_02772 5.7e-11 yppE S Bacterial domain of unknown function (DUF1798)
CINOAHEC_02774 1e-47 yppG S YppG-like protein
CINOAHEC_02775 7.3e-71 hspX O Belongs to the small heat shock protein (HSP20) family
CINOAHEC_02776 2.3e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
CINOAHEC_02777 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
CINOAHEC_02778 5.1e-237 yprB L RNase_H superfamily
CINOAHEC_02779 2.8e-91 ypsA S Belongs to the UPF0398 family
CINOAHEC_02780 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
CINOAHEC_02781 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
CINOAHEC_02783 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
CINOAHEC_02784 2.3e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CINOAHEC_02785 1.4e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CINOAHEC_02786 4.4e-186 ptxS K transcriptional
CINOAHEC_02787 8.4e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
CINOAHEC_02788 5e-102 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
CINOAHEC_02789 1.5e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
CINOAHEC_02790 7.4e-291 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CINOAHEC_02791 1.1e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
CINOAHEC_02792 1.5e-226 pbuX F xanthine
CINOAHEC_02793 2.8e-207 bcsA Q Naringenin-chalcone synthase
CINOAHEC_02794 1.5e-86 ypbQ S protein conserved in bacteria
CINOAHEC_02795 0.0 ypbR S Dynamin family
CINOAHEC_02796 5.5e-37 ypbS S Protein of unknown function (DUF2533)
CINOAHEC_02797 2e-07
CINOAHEC_02798 1.7e-165 polA 2.7.7.7 L 5'3' exonuclease
CINOAHEC_02800 1.8e-66 rnhA 3.1.26.4 L Ribonuclease
CINOAHEC_02801 2.9e-105 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CINOAHEC_02802 1.7e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
CINOAHEC_02803 2.6e-27 ypeQ S Zinc-finger
CINOAHEC_02804 8.1e-31 S Protein of unknown function (DUF2564)
CINOAHEC_02805 3.8e-16 degR
CINOAHEC_02806 7.9e-31 cspD K Cold-shock protein
CINOAHEC_02807 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
CINOAHEC_02808 4.7e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CINOAHEC_02809 6.8e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
CINOAHEC_02810 2.7e-80 ypgQ S phosphohydrolase
CINOAHEC_02811 3.4e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
CINOAHEC_02812 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
CINOAHEC_02813 1.7e-75 yphP S Belongs to the UPF0403 family
CINOAHEC_02814 5.9e-143 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
CINOAHEC_02815 8.6e-113 ypjP S YpjP-like protein
CINOAHEC_02816 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
CINOAHEC_02817 1e-153 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CINOAHEC_02818 4.8e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CINOAHEC_02819 1.2e-109 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
CINOAHEC_02820 4.2e-110 hlyIII S protein, Hemolysin III
CINOAHEC_02821 1.6e-185 pspF K Transcriptional regulator
CINOAHEC_02822 2.8e-243 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CINOAHEC_02823 3.4e-39 ypmP S Protein of unknown function (DUF2535)
CINOAHEC_02824 3.2e-109 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
CINOAHEC_02825 1.6e-137 ypmR E GDSL-like Lipase/Acylhydrolase
CINOAHEC_02826 1.1e-98 ypmS S protein conserved in bacteria
CINOAHEC_02827 5.5e-29 ypmT S Uncharacterized ympT
CINOAHEC_02828 1.1e-218 mepA V MATE efflux family protein
CINOAHEC_02829 1.6e-70 ypoP K transcriptional
CINOAHEC_02830 3.5e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CINOAHEC_02831 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
CINOAHEC_02832 5.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
CINOAHEC_02833 1.1e-209 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
CINOAHEC_02834 3.4e-185 cgeB S Spore maturation protein
CINOAHEC_02835 1.5e-65 cgeA
CINOAHEC_02836 3.5e-38 cgeC
CINOAHEC_02837 1.1e-255 cgeD M maturation of the outermost layer of the spore
CINOAHEC_02838 1.6e-143 yiiD K acetyltransferase
CINOAHEC_02840 8.1e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CINOAHEC_02841 1.7e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CINOAHEC_02842 8e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
CINOAHEC_02843 3.2e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
CINOAHEC_02844 7.9e-154 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
CINOAHEC_02845 5.1e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
CINOAHEC_02846 8.3e-47 yokU S YokU-like protein, putative antitoxin
CINOAHEC_02847 1.4e-36 yozE S Belongs to the UPF0346 family
CINOAHEC_02848 1.6e-123 yodN
CINOAHEC_02850 2.8e-24 yozD S YozD-like protein
CINOAHEC_02851 1.7e-105 yodM 3.6.1.27 I Acid phosphatase homologues
CINOAHEC_02852 3.6e-54 yodL S YodL-like
CINOAHEC_02853 5.3e-09
CINOAHEC_02854 4.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
CINOAHEC_02855 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
CINOAHEC_02856 5.2e-24 yodI
CINOAHEC_02857 6.3e-128 yodH Q Methyltransferase
CINOAHEC_02858 2.8e-252 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
CINOAHEC_02859 1.2e-269 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CINOAHEC_02860 6.2e-28 S Protein of unknown function (DUF3311)
CINOAHEC_02861 1.3e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
CINOAHEC_02862 6.5e-113 mhqD S Carboxylesterase
CINOAHEC_02863 4.8e-108 yodC C nitroreductase
CINOAHEC_02864 4.4e-55 yodB K transcriptional
CINOAHEC_02865 1.8e-63 yodA S tautomerase
CINOAHEC_02866 1.1e-205 gntP EG COG2610 H gluconate symporter and related permeases
CINOAHEC_02867 3.4e-09
CINOAHEC_02868 2e-56 yozR S COG0071 Molecular chaperone (small heat shock protein)
CINOAHEC_02869 1.2e-160 rarD S -transporter
CINOAHEC_02870 1.5e-43
CINOAHEC_02871 1.4e-59 yojF S Protein of unknown function (DUF1806)
CINOAHEC_02872 2.1e-125 yojG S deacetylase
CINOAHEC_02873 3.2e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CINOAHEC_02874 7.2e-245 norM V Multidrug efflux pump
CINOAHEC_02876 7.6e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CINOAHEC_02877 1.8e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
CINOAHEC_02878 1.2e-190 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
CINOAHEC_02879 6.6e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CINOAHEC_02880 2.1e-160 yojN S ATPase family associated with various cellular activities (AAA)
CINOAHEC_02881 0.0 yojO P Von Willebrand factor
CINOAHEC_02882 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
CINOAHEC_02883 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
CINOAHEC_02884 5.1e-168 yocS S -transporter
CINOAHEC_02885 4.5e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
CINOAHEC_02886 8.7e-164 sodA 1.15.1.1 P Superoxide dismutase
CINOAHEC_02887 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
CINOAHEC_02888 1.5e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
CINOAHEC_02889 2.7e-31 yozC
CINOAHEC_02890 4.2e-56 yozO S Bacterial PH domain
CINOAHEC_02891 1.9e-36 yocN
CINOAHEC_02892 1.1e-40 yozN
CINOAHEC_02893 1.8e-86 yocM O Belongs to the small heat shock protein (HSP20) family
CINOAHEC_02894 2e-30
CINOAHEC_02895 1.4e-53 yocL
CINOAHEC_02896 7.4e-83 dksA T general stress protein
CINOAHEC_02897 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CINOAHEC_02898 0.0 recQ 3.6.4.12 L DNA helicase
CINOAHEC_02899 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
CINOAHEC_02900 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CINOAHEC_02901 4.6e-197 desK 2.7.13.3 T Histidine kinase
CINOAHEC_02902 4.5e-202 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
CINOAHEC_02903 9.3e-186 yocD 3.4.17.13 V peptidase S66
CINOAHEC_02904 1.6e-93 yocC
CINOAHEC_02905 1.1e-144
CINOAHEC_02906 1.5e-92 yozB S membrane
CINOAHEC_02907 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
CINOAHEC_02908 1e-51 czrA K transcriptional
CINOAHEC_02909 8.8e-93 yobW
CINOAHEC_02910 9.3e-175 yobV K WYL domain
CINOAHEC_02911 8.3e-87 yobU K Bacterial transcription activator, effector binding domain
CINOAHEC_02912 1e-130 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
CINOAHEC_02913 1.3e-97 yobS K Transcriptional regulator
CINOAHEC_02914 1.1e-141 yobR 2.3.1.1 J FR47-like protein
CINOAHEC_02915 2.3e-133 yobQ K helix_turn_helix, arabinose operon control protein
CINOAHEC_02916 7.8e-52 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
CINOAHEC_02917 0.0 yobO M Pectate lyase superfamily protein
CINOAHEC_02918 1.1e-275 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
CINOAHEC_02919 4.8e-102 yokH G SMI1 / KNR4 family
CINOAHEC_02920 1.7e-39 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
CINOAHEC_02925 1.4e-37 S TM2 domain
CINOAHEC_02926 4e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
CINOAHEC_02927 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
CINOAHEC_02930 2.2e-168 bla 3.5.2.6 V beta-lactamase
CINOAHEC_02931 4.7e-114 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
CINOAHEC_02932 1e-75 yoaW
CINOAHEC_02933 3.7e-157 yijE EG EamA-like transporter family
CINOAHEC_02934 5.6e-158 yoaU K LysR substrate binding domain
CINOAHEC_02935 1.1e-147 yoaT S Protein of unknown function (DUF817)
CINOAHEC_02936 1.6e-36 yozG K Transcriptional regulator
CINOAHEC_02937 2.8e-74 yoaS S Protein of unknown function (DUF2975)
CINOAHEC_02938 7.1e-172 yoaR V vancomycin resistance protein
CINOAHEC_02939 3e-87
CINOAHEC_02941 3.5e-51 yoaQ S Evidence 4 Homologs of previously reported genes of
CINOAHEC_02942 1.5e-143 yoaP 3.1.3.18 K YoaP-like
CINOAHEC_02944 5.6e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
CINOAHEC_02947 1.6e-131 yoqW S Belongs to the SOS response-associated peptidase family
CINOAHEC_02948 7.3e-197 pelB 4.2.2.10, 4.2.2.2 G Amb_all
CINOAHEC_02949 6.8e-111 yoaK S Membrane
CINOAHEC_02950 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
CINOAHEC_02951 8.1e-279 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
CINOAHEC_02952 1.9e-178 mcpU NT methyl-accepting chemotaxis protein
CINOAHEC_02953 8.2e-37 S Protein of unknown function (DUF4025)
CINOAHEC_02954 2.6e-13
CINOAHEC_02955 6.5e-08 ywlA S Uncharacterised protein family (UPF0715)
CINOAHEC_02956 1.9e-33 yoaF
CINOAHEC_02957 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CINOAHEC_02958 2.9e-182 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CINOAHEC_02959 2.2e-279 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
CINOAHEC_02960 8.9e-234 yoaB EGP Major facilitator Superfamily
CINOAHEC_02961 1.1e-16 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
CINOAHEC_02962 3.1e-128 yoxB
CINOAHEC_02963 6e-38 yoxC S Bacterial protein of unknown function (DUF948)
CINOAHEC_02964 6.3e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
CINOAHEC_02965 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
CINOAHEC_02966 1.6e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CINOAHEC_02967 7.8e-205 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CINOAHEC_02968 7.8e-155 gltC K Transcriptional regulator
CINOAHEC_02969 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
CINOAHEC_02970 2.3e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
CINOAHEC_02971 6.7e-184 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
CINOAHEC_02972 1.1e-153 gltR1 K Transcriptional regulator
CINOAHEC_02973 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
CINOAHEC_02974 3e-34 yoeD G Helix-turn-helix domain
CINOAHEC_02975 2.2e-96 L Integrase
CINOAHEC_02977 1.8e-98 yoeB S IseA DL-endopeptidase inhibitor
CINOAHEC_02978 2.3e-246 yoeA V MATE efflux family protein
CINOAHEC_02979 2.1e-190 yoxA 5.1.3.3 G Aldose 1-epimerase
CINOAHEC_02980 6.8e-273 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
CINOAHEC_02981 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CINOAHEC_02982 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CINOAHEC_02983 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CINOAHEC_02984 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CINOAHEC_02985 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
CINOAHEC_02986 2.8e-64 yngL S Protein of unknown function (DUF1360)
CINOAHEC_02987 1.9e-302 yngK T Glycosyl hydrolase-like 10
CINOAHEC_02989 1.7e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
CINOAHEC_02990 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
CINOAHEC_02991 3.3e-250 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
CINOAHEC_02992 1.7e-31 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
CINOAHEC_02993 1.5e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
CINOAHEC_02994 3.2e-136 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
CINOAHEC_02995 4.5e-288 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
CINOAHEC_02996 3.3e-233 nrnB S phosphohydrolase (DHH superfamily)
CINOAHEC_02997 5.5e-104 yngC S membrane-associated protein
CINOAHEC_02998 5.9e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
CINOAHEC_02999 2e-79 yngA S membrane
CINOAHEC_03000 4.7e-293 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
CINOAHEC_03001 3.7e-251 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
CINOAHEC_03003 6e-293 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
CINOAHEC_03004 9e-251 agcS E Sodium alanine symporter
CINOAHEC_03005 1.3e-57 ynfC
CINOAHEC_03006 2.3e-12
CINOAHEC_03007 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CINOAHEC_03008 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CINOAHEC_03009 6.6e-69 yccU S CoA-binding protein
CINOAHEC_03010 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CINOAHEC_03011 4.1e-49 yneR S Belongs to the HesB IscA family
CINOAHEC_03012 1.3e-53 yneQ
CINOAHEC_03013 1.2e-73 yneP S Thioesterase-like superfamily
CINOAHEC_03014 1.1e-34 tlp S Belongs to the Tlp family
CINOAHEC_03015 3.1e-08 sspN S Small acid-soluble spore protein N family
CINOAHEC_03017 2.7e-91 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CINOAHEC_03018 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CINOAHEC_03019 2.2e-14 sspO S Belongs to the SspO family
CINOAHEC_03020 3.9e-19 sspP S Belongs to the SspP family
CINOAHEC_03021 5.9e-64 hspX O Spore coat protein
CINOAHEC_03022 7.2e-74 yneK S Protein of unknown function (DUF2621)
CINOAHEC_03023 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
CINOAHEC_03024 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
CINOAHEC_03025 7.1e-127 ccdA O cytochrome c biogenesis protein
CINOAHEC_03026 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
CINOAHEC_03027 1.8e-28 yneF S UPF0154 protein
CINOAHEC_03028 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
CINOAHEC_03029 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CINOAHEC_03030 1.3e-32 ynzC S UPF0291 protein
CINOAHEC_03031 4.5e-112 yneB L resolvase
CINOAHEC_03032 9.9e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
CINOAHEC_03033 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CINOAHEC_03034 2.2e-16 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
CINOAHEC_03035 8.9e-32 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
CINOAHEC_03036 3.7e-73 yndM S Protein of unknown function (DUF2512)
CINOAHEC_03037 4.7e-137 yndL S Replication protein
CINOAHEC_03039 1.8e-306 yndJ S YndJ-like protein
CINOAHEC_03040 8.4e-116 yndH S Domain of unknown function (DUF4166)
CINOAHEC_03041 3.5e-132 yndG S DoxX-like family
CINOAHEC_03042 6.1e-219 gerLC S Spore germination protein
CINOAHEC_03043 9.1e-136 gerAB U Spore germination
CINOAHEC_03044 3.4e-283 gerAA EG Spore germination protein
CINOAHEC_03047 2.6e-79 yndB S Activator of Hsp90 ATPase homolog 1-like protein
CINOAHEC_03048 5.3e-71
CINOAHEC_03049 7.9e-25 tatA U protein secretion
CINOAHEC_03052 7e-133 S Domain of unknown function, YrpD
CINOAHEC_03054 8.7e-89 S Thymidylate synthase
CINOAHEC_03062 1.3e-09
CINOAHEC_03063 7.8e-08
CINOAHEC_03072 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CINOAHEC_03073 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CINOAHEC_03074 2.9e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
CINOAHEC_03075 5.8e-285 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
CINOAHEC_03076 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
CINOAHEC_03077 9.3e-75 tspO T membrane
CINOAHEC_03078 4.4e-205 cotI S Spore coat protein
CINOAHEC_03079 6.9e-217 cotSA M Glycosyl transferases group 1
CINOAHEC_03080 9.7e-205 cotS S Seems to be required for the assembly of the CotSA protein in spores
CINOAHEC_03082 1.7e-232 ytcC M Glycosyltransferase Family 4
CINOAHEC_03083 3.1e-178 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
CINOAHEC_03084 1.6e-241 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CINOAHEC_03085 4.3e-152 galU 2.7.7.9 M Nucleotidyl transferase
CINOAHEC_03086 2.6e-132 dksA T COG1734 DnaK suppressor protein
CINOAHEC_03087 2.1e-271 menF 5.4.4.2 HQ Isochorismate synthase
CINOAHEC_03088 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CINOAHEC_03089 1.6e-154 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
CINOAHEC_03090 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CINOAHEC_03091 1.7e-276 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
CINOAHEC_03092 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
CINOAHEC_03093 1.8e-170 troA P Belongs to the bacterial solute-binding protein 9 family
CINOAHEC_03094 3.6e-137 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
CINOAHEC_03095 5.3e-229 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
CINOAHEC_03096 3.4e-150 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
CINOAHEC_03097 1.1e-24 S Domain of Unknown Function (DUF1540)
CINOAHEC_03098 3.6e-188 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
CINOAHEC_03099 3.1e-248 cydA 1.10.3.14 C oxidase, subunit
CINOAHEC_03100 3.6e-41 rpmE2 J Ribosomal protein L31
CINOAHEC_03101 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
CINOAHEC_03102 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
CINOAHEC_03103 1.1e-72 ytkA S YtkA-like
CINOAHEC_03105 2.1e-76 dps P Belongs to the Dps family
CINOAHEC_03106 3.5e-62 ytkC S Bacteriophage holin family
CINOAHEC_03107 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
CINOAHEC_03108 6.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
CINOAHEC_03109 1.4e-144 ytlC P ABC transporter
CINOAHEC_03110 4.2e-189 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
CINOAHEC_03111 2.7e-148 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
CINOAHEC_03112 2.1e-38 ytmB S Protein of unknown function (DUF2584)
CINOAHEC_03113 9.7e-310 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CINOAHEC_03114 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CINOAHEC_03115 0.0 asnB 6.3.5.4 E Asparagine synthase
CINOAHEC_03116 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
CINOAHEC_03117 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CINOAHEC_03118 9.5e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
CINOAHEC_03119 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
CINOAHEC_03120 2.4e-104 ytqB J Putative rRNA methylase
CINOAHEC_03121 2.3e-189 yhcC S Fe-S oxidoreductase
CINOAHEC_03122 6.7e-41 ytzC S Protein of unknown function (DUF2524)
CINOAHEC_03124 5.1e-66 ytrA K GntR family transcriptional regulator
CINOAHEC_03125 4.2e-161 ytrB P abc transporter atp-binding protein
CINOAHEC_03126 2.1e-153 P ABC-2 family transporter protein
CINOAHEC_03127 1.3e-147
CINOAHEC_03128 9.1e-127 ytrE V ABC transporter, ATP-binding protein
CINOAHEC_03129 3.6e-233 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
CINOAHEC_03130 1.1e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CINOAHEC_03131 1.6e-185 T PhoQ Sensor
CINOAHEC_03132 6.2e-137 bceA V ABC transporter, ATP-binding protein
CINOAHEC_03133 0.0 bceB V ABC transporter (permease)
CINOAHEC_03134 4.3e-42 yttA 2.7.13.3 S Pfam Transposase IS66
CINOAHEC_03135 3e-210 yttB EGP Major facilitator Superfamily
CINOAHEC_03136 1.5e-141 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
CINOAHEC_03137 7.7e-55 ytvB S Protein of unknown function (DUF4257)
CINOAHEC_03138 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
CINOAHEC_03139 8.1e-51 ytwF P Sulfurtransferase
CINOAHEC_03140 2.6e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
CINOAHEC_03141 9.8e-144 amyC P ABC transporter (permease)
CINOAHEC_03142 6.2e-168 amyD P ABC transporter
CINOAHEC_03143 1.4e-245 msmE G Bacterial extracellular solute-binding protein
CINOAHEC_03144 1.2e-188 msmR K Transcriptional regulator
CINOAHEC_03145 4.1e-172 ytaP S Acetyl xylan esterase (AXE1)
CINOAHEC_03146 2.1e-148 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
CINOAHEC_03147 1.1e-258 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
CINOAHEC_03148 3.3e-214 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
CINOAHEC_03149 2.5e-124 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CINOAHEC_03150 4.2e-189 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CINOAHEC_03151 5.5e-225 bioI 1.14.14.46 C Cytochrome P450
CINOAHEC_03152 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
CINOAHEC_03153 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
CINOAHEC_03154 4.4e-288 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
CINOAHEC_03155 0.0 ytdP K Transcriptional regulator
CINOAHEC_03156 1.7e-171 lplB G COG4209 ABC-type polysaccharide transport system, permease component
CINOAHEC_03157 8e-218 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
CINOAHEC_03158 1.3e-72 yteS G transport
CINOAHEC_03159 5e-256 yteT S Oxidoreductase family, C-terminal alpha/beta domain
CINOAHEC_03160 5.3e-116 yteU S Integral membrane protein
CINOAHEC_03161 3.1e-26 yteV S Sporulation protein Cse60
CINOAHEC_03162 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
CINOAHEC_03163 2.6e-230 ytfP S HI0933-like protein
CINOAHEC_03164 2.1e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CINOAHEC_03165 6.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CINOAHEC_03166 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
CINOAHEC_03167 4.8e-131 ythP V ABC transporter
CINOAHEC_03168 9.3e-201 ythQ U Bacterial ABC transporter protein EcsB
CINOAHEC_03169 7.2e-226 pbuO S permease
CINOAHEC_03170 1.9e-269 pepV 3.5.1.18 E Dipeptidase
CINOAHEC_03171 1.9e-172 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
CINOAHEC_03172 5.6e-103 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CINOAHEC_03173 1.3e-165 ytlQ
CINOAHEC_03174 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
CINOAHEC_03175 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
CINOAHEC_03176 2.3e-150 ytmP 2.7.1.89 M Phosphotransferase
CINOAHEC_03177 2e-45 ytzH S YtzH-like protein
CINOAHEC_03178 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
CINOAHEC_03179 2.7e-149 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
CINOAHEC_03180 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
CINOAHEC_03181 9.8e-52 ytzB S small secreted protein
CINOAHEC_03182 1.4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
CINOAHEC_03183 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
CINOAHEC_03184 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
CINOAHEC_03185 9.8e-149 ytpQ S Belongs to the UPF0354 family
CINOAHEC_03186 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CINOAHEC_03187 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
CINOAHEC_03188 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
CINOAHEC_03189 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CINOAHEC_03190 6.6e-17 ytxH S COG4980 Gas vesicle protein
CINOAHEC_03191 4.8e-54 ytxJ O Protein of unknown function (DUF2847)
CINOAHEC_03192 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
CINOAHEC_03193 1.7e-182 ccpA K catabolite control protein A
CINOAHEC_03194 1.3e-145 motA N flagellar motor
CINOAHEC_03195 6.8e-125 motS N Flagellar motor protein
CINOAHEC_03196 4.3e-225 acuC BQ histone deacetylase
CINOAHEC_03197 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
CINOAHEC_03198 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
CINOAHEC_03199 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
CINOAHEC_03200 1.8e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CINOAHEC_03202 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CINOAHEC_03203 2e-308 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
CINOAHEC_03204 5.9e-88 ytsP 1.8.4.14 T GAF domain-containing protein
CINOAHEC_03205 1e-108 yttP K Transcriptional regulator
CINOAHEC_03206 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
CINOAHEC_03207 2e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CINOAHEC_03208 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
CINOAHEC_03209 5.9e-208 iscS2 2.8.1.7 E Cysteine desulfurase
CINOAHEC_03210 5.1e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CINOAHEC_03211 2e-29 sspB S spore protein
CINOAHEC_03212 2.3e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
CINOAHEC_03213 0.0 ytcJ S amidohydrolase
CINOAHEC_03214 2.4e-147 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CINOAHEC_03215 5.1e-179 sppA OU signal peptide peptidase SppA
CINOAHEC_03216 8.5e-87 yteJ S RDD family
CINOAHEC_03217 4.7e-115 ytfI S Protein of unknown function (DUF2953)
CINOAHEC_03218 8.7e-70 ytfJ S Sporulation protein YtfJ
CINOAHEC_03219 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CINOAHEC_03220 7e-165 ytxK 2.1.1.72 L DNA methylase
CINOAHEC_03221 4.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CINOAHEC_03222 1.4e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
CINOAHEC_03223 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
CINOAHEC_03224 1.2e-266 argH 4.3.2.1 E argininosuccinate lyase
CINOAHEC_03226 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CINOAHEC_03227 1.7e-130 ytkL S Belongs to the UPF0173 family
CINOAHEC_03228 1.2e-171 ytlI K LysR substrate binding domain
CINOAHEC_03229 4.3e-100 ytmI K Acetyltransferase (GNAT) domain
CINOAHEC_03230 8.3e-148 tcyK ET Bacterial periplasmic substrate-binding proteins
CINOAHEC_03231 3.2e-144 tcyK M Bacterial periplasmic substrate-binding proteins
CINOAHEC_03232 1.8e-122 tcyL P Binding-protein-dependent transport system inner membrane component
CINOAHEC_03233 5.4e-119 tcyM U Binding-protein-dependent transport system inner membrane component
CINOAHEC_03234 3.9e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
CINOAHEC_03235 1.7e-182 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CINOAHEC_03236 5.4e-46 ytnI O COG0695 Glutaredoxin and related proteins
CINOAHEC_03237 4.9e-254 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CINOAHEC_03238 3.4e-126 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
CINOAHEC_03239 7.3e-236 ytnL 3.5.1.47 E hydrolase activity
CINOAHEC_03240 1.4e-156 ytnM S membrane transporter protein
CINOAHEC_03241 8e-241 ytoI K transcriptional regulator containing CBS domains
CINOAHEC_03242 2.4e-47 ytpI S YtpI-like protein
CINOAHEC_03243 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
CINOAHEC_03244 9.2e-29
CINOAHEC_03245 1.8e-68 ytrI
CINOAHEC_03246 3.2e-56 ytrH S Sporulation protein YtrH
CINOAHEC_03247 0.0 dnaE 2.7.7.7 L DNA polymerase
CINOAHEC_03248 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
CINOAHEC_03249 3.2e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CINOAHEC_03250 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
CINOAHEC_03251 3.4e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
CINOAHEC_03252 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
CINOAHEC_03253 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
CINOAHEC_03254 9.9e-192 ytvI S sporulation integral membrane protein YtvI
CINOAHEC_03255 2.3e-70 yeaL S membrane
CINOAHEC_03256 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
CINOAHEC_03257 4.1e-242 icd 1.1.1.42 C isocitrate
CINOAHEC_03258 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
CINOAHEC_03259 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CINOAHEC_03260 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
CINOAHEC_03261 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CINOAHEC_03262 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
CINOAHEC_03263 1.1e-107 ytaF P Probably functions as a manganese efflux pump
CINOAHEC_03264 4.9e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CINOAHEC_03265 8.9e-161 ytbE S reductase
CINOAHEC_03266 7.3e-201 ytbD EGP Major facilitator Superfamily
CINOAHEC_03267 9.9e-67 ytcD K Transcriptional regulator
CINOAHEC_03268 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CINOAHEC_03269 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CINOAHEC_03270 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CINOAHEC_03271 7.7e-266 dnaB L Membrane attachment protein
CINOAHEC_03272 6.6e-173 dnaI L Primosomal protein DnaI
CINOAHEC_03273 4.9e-111 ytxB S SNARE associated Golgi protein
CINOAHEC_03274 3.8e-159 ytxC S YtxC-like family
CINOAHEC_03275 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CINOAHEC_03276 7.3e-149 ysaA S HAD-hyrolase-like
CINOAHEC_03277 0.0 lytS 2.7.13.3 T Histidine kinase
CINOAHEC_03278 3.1e-130 lytT T COG3279 Response regulator of the LytR AlgR family
CINOAHEC_03279 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
CINOAHEC_03280 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
CINOAHEC_03282 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CINOAHEC_03283 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
CINOAHEC_03284 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CINOAHEC_03285 7.5e-45 ysdA S Membrane
CINOAHEC_03286 9.2e-68 ysdB S Sigma-w pathway protein YsdB
CINOAHEC_03287 6.4e-204 ysdC G COG1363 Cellulase M and related proteins
CINOAHEC_03288 3.1e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
CINOAHEC_03289 2.7e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
CINOAHEC_03290 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
CINOAHEC_03291 2.4e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
CINOAHEC_03292 1.3e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
CINOAHEC_03293 1.3e-218 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
CINOAHEC_03294 6.2e-254 araN G carbohydrate transport
CINOAHEC_03295 2.7e-166 araP G carbohydrate transport
CINOAHEC_03296 4.9e-143 araQ G transport system permease
CINOAHEC_03297 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
CINOAHEC_03298 0.0 cstA T Carbon starvation protein
CINOAHEC_03299 3.4e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
CINOAHEC_03300 1.7e-254 glcF C Glycolate oxidase
CINOAHEC_03301 1.8e-262 glcD 1.1.3.15 C Glycolate oxidase subunit
CINOAHEC_03302 1e-204 ysfB KT regulator
CINOAHEC_03303 2.6e-32 sspI S Belongs to the SspI family
CINOAHEC_03304 9.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CINOAHEC_03305 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CINOAHEC_03306 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CINOAHEC_03307 5.4e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CINOAHEC_03308 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CINOAHEC_03309 1.3e-85 cvpA S membrane protein, required for colicin V production
CINOAHEC_03310 0.0 polX L COG1796 DNA polymerase IV (family X)
CINOAHEC_03311 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
CINOAHEC_03312 7.3e-68 yshE S membrane
CINOAHEC_03313 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
CINOAHEC_03314 2.7e-100 fadR K Transcriptional regulator
CINOAHEC_03315 1.2e-135 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
CINOAHEC_03316 4.5e-135 etfB C Electron transfer flavoprotein
CINOAHEC_03317 4.2e-178 etfA C Electron transfer flavoprotein
CINOAHEC_03319 8.9e-305 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
CINOAHEC_03320 2e-52 trxA O Belongs to the thioredoxin family
CINOAHEC_03321 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
CINOAHEC_03322 5.4e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
CINOAHEC_03323 1.2e-79 yslB S Protein of unknown function (DUF2507)
CINOAHEC_03324 2.4e-107 sdhC C succinate dehydrogenase
CINOAHEC_03325 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
CINOAHEC_03326 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
CINOAHEC_03327 1.7e-78 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
CINOAHEC_03328 3.3e-30 gerE K Transcriptional regulator
CINOAHEC_03329 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
CINOAHEC_03330 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
CINOAHEC_03331 6.5e-196 gerM S COG5401 Spore germination protein
CINOAHEC_03332 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CINOAHEC_03333 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CINOAHEC_03334 4.1e-92 ysnB S Phosphoesterase
CINOAHEC_03336 9.1e-134 ysnF S protein conserved in bacteria
CINOAHEC_03337 4.8e-76 ysnE K acetyltransferase
CINOAHEC_03339 0.0 ilvB 2.2.1.6 E Acetolactate synthase
CINOAHEC_03340 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
CINOAHEC_03341 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CINOAHEC_03342 2.2e-290 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CINOAHEC_03343 3.7e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
CINOAHEC_03344 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CINOAHEC_03345 1.5e-114 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CINOAHEC_03346 2.3e-187 ysoA H Tetratricopeptide repeat
CINOAHEC_03347 2.7e-225 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
CINOAHEC_03348 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CINOAHEC_03349 9.2e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
CINOAHEC_03350 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CINOAHEC_03351 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
CINOAHEC_03352 7e-89 ysxD
CINOAHEC_03353 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CINOAHEC_03354 3.6e-146 hemX O cytochrome C
CINOAHEC_03355 4.3e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
CINOAHEC_03356 7.9e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
CINOAHEC_03357 6.2e-182 hemB 4.2.1.24 H Belongs to the ALAD family
CINOAHEC_03358 2.5e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
CINOAHEC_03359 6.4e-190 spoVID M stage VI sporulation protein D
CINOAHEC_03360 7.8e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CINOAHEC_03361 1.6e-25
CINOAHEC_03362 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
CINOAHEC_03363 1.4e-245 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
CINOAHEC_03364 1.5e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
CINOAHEC_03365 3.3e-162 spoIIB S Sporulation related domain
CINOAHEC_03366 2.8e-102 maf D septum formation protein Maf
CINOAHEC_03367 9.8e-68 radC E Belongs to the UPF0758 family
CINOAHEC_03368 7.6e-229 S Recombinase
CINOAHEC_03369 4.5e-71 S Pfam:Peptidase_M78
CINOAHEC_03370 8.9e-64 S sequence-specific DNA binding
CINOAHEC_03371 8.8e-09 plcR K helix-turn-helix
CINOAHEC_03374 3.5e-21 S Uncharacterized protein YqaH
CINOAHEC_03376 1.3e-91 S DNA protection
CINOAHEC_03377 7.1e-167 tadZ D AAA domain
CINOAHEC_03379 1.5e-74 S Protein of unknown function (DUF669)
CINOAHEC_03380 0.0 S hydrolase activity
CINOAHEC_03381 6.2e-65
CINOAHEC_03382 2.3e-93 S nuclease activity
CINOAHEC_03383 2.1e-80
CINOAHEC_03385 3.3e-20 S YopX protein
CINOAHEC_03388 1.5e-59
CINOAHEC_03392 6.2e-50 V HNH endonuclease
CINOAHEC_03393 2e-78 L phage terminase small subunit
CINOAHEC_03394 2.5e-303 S Terminase
CINOAHEC_03395 2.2e-174 S Phage portal protein
CINOAHEC_03396 3.4e-80 S peptidase activity
CINOAHEC_03397 1.6e-156 gp36 S capsid protein
CINOAHEC_03398 4e-21
CINOAHEC_03399 1.3e-37 S Phage gp6-like head-tail connector protein
CINOAHEC_03400 1.4e-37 S Phage head-tail joining protein
CINOAHEC_03401 1.8e-50 S Bacteriophage HK97-gp10, putative tail-component
CINOAHEC_03403 3.4e-77 S Phage tail tube protein
CINOAHEC_03406 0.0 D phage tail tape measure protein
CINOAHEC_03407 1.7e-111 S Phage tail protein
CINOAHEC_03408 3.5e-220 NU Prophage endopeptidase tail
CINOAHEC_03409 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
CINOAHEC_03410 6.1e-88
CINOAHEC_03411 1.3e-12
CINOAHEC_03413 8.5e-95 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
CINOAHEC_03414 2.1e-57 S Bacteriophage holin family
CINOAHEC_03415 4.4e-127 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
CINOAHEC_03416 8.3e-67 S Immunity protein 70
CINOAHEC_03417 1.1e-178 A Pre-toxin TG
CINOAHEC_03418 5.9e-12
CINOAHEC_03421 4.2e-15 K Helix-turn-helix domain
CINOAHEC_03422 5.4e-08
CINOAHEC_03423 2.2e-23
CINOAHEC_03424 2.2e-99
CINOAHEC_03426 5.4e-51 radC E Belongs to the UPF0758 family
CINOAHEC_03427 1.8e-184 mreB D Rod shape-determining protein MreB
CINOAHEC_03428 2.8e-157 mreC M Involved in formation and maintenance of cell shape
CINOAHEC_03429 1.4e-84 mreD M shape-determining protein
CINOAHEC_03430 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
CINOAHEC_03431 4.7e-143 minD D Belongs to the ParA family
CINOAHEC_03432 1.1e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
CINOAHEC_03433 2.7e-160 spoIVFB S Stage IV sporulation protein
CINOAHEC_03434 1.3e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
CINOAHEC_03435 4.1e-56 ysxB J ribosomal protein
CINOAHEC_03436 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
CINOAHEC_03437 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
CINOAHEC_03438 5.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CINOAHEC_03439 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
CINOAHEC_03440 7.6e-163 pheA 4.2.1.51 E Prephenate dehydratase
CINOAHEC_03441 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
CINOAHEC_03442 5e-218 nifS 2.8.1.7 E Cysteine desulfurase
CINOAHEC_03443 7.3e-305 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
CINOAHEC_03444 7.3e-158 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
CINOAHEC_03445 1.8e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CINOAHEC_03446 9.8e-158 safA M spore coat assembly protein SafA
CINOAHEC_03447 2.2e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
CINOAHEC_03448 1.6e-126 yebC K transcriptional regulatory protein
CINOAHEC_03449 5.3e-262 alsT E Sodium alanine symporter
CINOAHEC_03450 4e-51 S Family of unknown function (DUF5412)
CINOAHEC_03452 6.5e-119 yrzF T serine threonine protein kinase
CINOAHEC_03453 1.4e-192 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
CINOAHEC_03454 2e-252 csbX EGP Major facilitator Superfamily
CINOAHEC_03455 4.8e-93 bofC S BofC C-terminal domain
CINOAHEC_03456 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
CINOAHEC_03457 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
CINOAHEC_03458 1e-17 yrzS S Protein of unknown function (DUF2905)
CINOAHEC_03459 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CINOAHEC_03460 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
CINOAHEC_03461 1.1e-38 yajC U Preprotein translocase subunit YajC
CINOAHEC_03462 6.4e-73 yrzE S Protein of unknown function (DUF3792)
CINOAHEC_03463 1.7e-111 yrbG S membrane
CINOAHEC_03464 2.4e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CINOAHEC_03465 1.6e-48 yrzD S Post-transcriptional regulator
CINOAHEC_03466 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CINOAHEC_03467 1.1e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
CINOAHEC_03468 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
CINOAHEC_03469 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
CINOAHEC_03470 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CINOAHEC_03471 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CINOAHEC_03472 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CINOAHEC_03473 9.7e-262 lytH 3.5.1.28 M COG3103 SH3 domain protein
CINOAHEC_03475 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
CINOAHEC_03476 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CINOAHEC_03477 9e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
CINOAHEC_03478 3.3e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
CINOAHEC_03479 1.2e-70 cymR K Transcriptional regulator
CINOAHEC_03480 3.3e-211 iscS 2.8.1.7 E Cysteine desulfurase
CINOAHEC_03481 2.5e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
CINOAHEC_03482 1.4e-15 S COG0457 FOG TPR repeat
CINOAHEC_03483 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
CINOAHEC_03484 1.2e-82 yrrD S protein conserved in bacteria
CINOAHEC_03485 9.8e-31 yrzR
CINOAHEC_03486 8e-08 S Protein of unknown function (DUF3918)
CINOAHEC_03487 6.4e-106 glnP P ABC transporter
CINOAHEC_03488 4e-108 gluC P ABC transporter
CINOAHEC_03489 4.8e-143 glnH ET Belongs to the bacterial solute-binding protein 3 family
CINOAHEC_03490 5.4e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
CINOAHEC_03491 6e-162 yrrI S AI-2E family transporter
CINOAHEC_03492 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CINOAHEC_03493 1.7e-41 yrzL S Belongs to the UPF0297 family
CINOAHEC_03494 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CINOAHEC_03495 1.2e-45 yrzB S Belongs to the UPF0473 family
CINOAHEC_03496 8.2e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CINOAHEC_03497 2.9e-119 yrrM 2.1.1.104 S O-methyltransferase
CINOAHEC_03498 2.9e-173 yegQ O Peptidase U32
CINOAHEC_03499 2.7e-246 yegQ O COG0826 Collagenase and related proteases
CINOAHEC_03500 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
CINOAHEC_03501 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CINOAHEC_03502 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
CINOAHEC_03503 9.7e-60 yrrS S Protein of unknown function (DUF1510)
CINOAHEC_03504 1e-25 yrzA S Protein of unknown function (DUF2536)
CINOAHEC_03505 2.2e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
CINOAHEC_03506 2.7e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CINOAHEC_03507 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
CINOAHEC_03508 1.3e-210 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
CINOAHEC_03509 4.6e-35 yrhC S YrhC-like protein
CINOAHEC_03510 2.4e-78 yrhD S Protein of unknown function (DUF1641)
CINOAHEC_03511 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
CINOAHEC_03512 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
CINOAHEC_03513 1.8e-142 focA P Formate nitrite
CINOAHEC_03516 7.2e-95 yrhH Q methyltransferase
CINOAHEC_03517 3.3e-101 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
CINOAHEC_03518 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
CINOAHEC_03519 4.3e-168 capL C PFAM UDP-glucose GDP-mannose dehydrogenase
CINOAHEC_03520 2.6e-119 wbpP 5.1.3.2, 5.1.3.7 GM NmrA-like family
CINOAHEC_03521 9.4e-117 S ATPases associated with a variety of cellular activities
CINOAHEC_03522 5.7e-64 S ABC-2 family transporter protein
CINOAHEC_03523 1.1e-62 S ABC-2 family transporter protein
CINOAHEC_03524 7.2e-104 Q TIGRFAM amino acid adenylation domain
CINOAHEC_03525 2e-46 hopR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
CINOAHEC_03526 6.6e-181 hutH 4.3.1.23, 4.3.1.24, 4.3.1.3, 5.4.3.6 E Aromatic amino acid lyase
CINOAHEC_03527 2.6e-100 EF ATP-grasp domain
CINOAHEC_03528 6.6e-88 yodQ 3.5.1.16 E Acetylornithine deacetylase
CINOAHEC_03529 1.5e-52 S dehydrogenases and related proteins
CINOAHEC_03530 3.9e-11 O Butirosin biosynthesis protein H, N-terminal
CINOAHEC_03531 7.3e-29 S Butirosin biosynthesis protein H, N-terminal
CINOAHEC_03532 3.2e-17 yrhK S YrhK-like protein
CINOAHEC_03533 2.4e-227 yrhL I Acyltransferase family
CINOAHEC_03534 5.5e-77 yrhL I Acyltransferase family
CINOAHEC_03535 1.6e-148 rsiV S Protein of unknown function (DUF3298)
CINOAHEC_03536 3.1e-150 yrhO K Archaeal transcriptional regulator TrmB
CINOAHEC_03537 3.6e-106 yrhP E LysE type translocator
CINOAHEC_03538 3.3e-253 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
CINOAHEC_03539 0.0 levR K PTS system fructose IIA component
CINOAHEC_03540 1.9e-74 levD 2.7.1.202 G PTS system fructose IIA component
CINOAHEC_03541 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
CINOAHEC_03542 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
CINOAHEC_03543 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
CINOAHEC_03544 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
CINOAHEC_03545 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
CINOAHEC_03546 3.9e-198 adhA 1.1.1.1 C alcohol dehydrogenase
CINOAHEC_03547 1.6e-28 yphJ 4.1.1.44 S peroxiredoxin activity
CINOAHEC_03548 1.6e-46 yraB K helix_turn_helix, mercury resistance
CINOAHEC_03549 1.1e-49 yraD M Spore coat protein
CINOAHEC_03550 7.5e-26 yraE
CINOAHEC_03551 3.8e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
CINOAHEC_03552 6.4e-63 yraF M Spore coat protein
CINOAHEC_03553 1.5e-36 yraG
CINOAHEC_03554 3.8e-66 E Glyoxalase-like domain
CINOAHEC_03556 2.4e-61 T sh3 domain protein
CINOAHEC_03557 1.7e-60 T sh3 domain protein
CINOAHEC_03558 4.9e-148 S Alpha beta hydrolase
CINOAHEC_03559 2.1e-39 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CINOAHEC_03560 1.5e-149 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
CINOAHEC_03561 6.5e-204 yraM S PrpF protein
CINOAHEC_03562 3.7e-162 yraN K Transcriptional regulator
CINOAHEC_03563 4e-224 yraO C Citrate transporter
CINOAHEC_03564 3.8e-187 yrpG C Aldo/keto reductase family
CINOAHEC_03565 1.2e-91 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
CINOAHEC_03566 1.3e-113 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
CINOAHEC_03567 2.2e-47 yjbR S YjbR
CINOAHEC_03568 7.2e-118 bmrR K helix_turn_helix, mercury resistance
CINOAHEC_03569 5.6e-98 flr S Flavin reductase like domain
CINOAHEC_03570 6.4e-135 tktA 2.2.1.1 G COG3959 Transketolase, N-terminal subunit
CINOAHEC_03571 7e-154 2.2.1.1 G Transketolase, pyrimidine binding domain
CINOAHEC_03572 4.3e-114 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CINOAHEC_03573 2.8e-209 rbtT P Major Facilitator Superfamily
CINOAHEC_03575 1.5e-100 K helix_turn_helix gluconate operon transcriptional repressor
CINOAHEC_03576 1.6e-123 yrpD S Domain of unknown function, YrpD
CINOAHEC_03577 4.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
CINOAHEC_03579 8.4e-193 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
CINOAHEC_03580 3.5e-165 aadK G Streptomycin adenylyltransferase
CINOAHEC_03581 6.4e-90 yrdA S DinB family
CINOAHEC_03582 5.7e-54 S Protein of unknown function (DUF2568)
CINOAHEC_03583 4.5e-100 yrdC 3.5.1.19 Q Isochorismatase family
CINOAHEC_03584 9.2e-231 cypA C Cytochrome P450
CINOAHEC_03585 1.2e-15 yrdF K ribonuclease inhibitor
CINOAHEC_03586 6.3e-79 bkdR K helix_turn_helix ASNC type
CINOAHEC_03587 2.8e-137 azlC E AzlC protein
CINOAHEC_03588 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
CINOAHEC_03589 2.5e-226 brnQ E Component of the transport system for branched-chain amino acids
CINOAHEC_03590 3.8e-162 gltR K LysR substrate binding domain
CINOAHEC_03591 2.4e-62 yodA S tautomerase
CINOAHEC_03592 4e-149 czcD P COG1230 Co Zn Cd efflux system component
CINOAHEC_03593 1e-198 trkA P Oxidoreductase
CINOAHEC_03594 1e-159 yrdQ K Transcriptional regulator
CINOAHEC_03595 1.4e-170 yrdR EG EamA-like transporter family
CINOAHEC_03596 3.9e-16 S YrzO-like protein
CINOAHEC_03597 5.1e-232 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
CINOAHEC_03598 5.9e-82 bltD 2.3.1.57 K FR47-like protein
CINOAHEC_03599 3.3e-209 blt EGP Major facilitator Superfamily
CINOAHEC_03600 3.1e-150 bltR K helix_turn_helix, mercury resistance
CINOAHEC_03601 1.4e-106 yrkC G Cupin domain
CINOAHEC_03602 7.8e-39 yrkD S protein conserved in bacteria
CINOAHEC_03603 7.3e-83 yrkE O DsrE/DsrF/DrsH-like family
CINOAHEC_03604 1.8e-96 yrkF OP Belongs to the sulfur carrier protein TusA family
CINOAHEC_03605 5e-162 yrkH P Rhodanese Homology Domain
CINOAHEC_03606 6e-165 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
CINOAHEC_03607 1.1e-216 mepA V Multidrug transporter MatE
CINOAHEC_03608 3.3e-113 tetR3 K Transcriptional regulator
CINOAHEC_03609 6.1e-62 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CINOAHEC_03610 4.4e-94 yqaB E IrrE N-terminal-like domain
CINOAHEC_03611 1e-101 adk 2.7.4.3 F adenylate kinase activity
CINOAHEC_03613 1.1e-56 K sequence-specific DNA binding
CINOAHEC_03614 6.5e-37 K Helix-turn-helix XRE-family like proteins
CINOAHEC_03616 4.4e-103
CINOAHEC_03617 9.7e-36 3.1.3.16 L DnaD domain protein
CINOAHEC_03618 1.6e-127 xkdC L IstB-like ATP binding protein
CINOAHEC_03621 1.4e-54 S Protein of unknown function (DUF1064)
CINOAHEC_03623 7.1e-27 yqaO S Phage-like element PBSX protein XtrA
CINOAHEC_03628 4e-08 S YopX protein
CINOAHEC_03633 4.5e-62
CINOAHEC_03640 1.9e-80 L Transposase
CINOAHEC_03641 1.4e-45 L Terminase small subunit
CINOAHEC_03642 2.6e-196 S Phage terminase large subunit
CINOAHEC_03643 3.1e-121 S Phage portal protein, SPP1 Gp6-like
CINOAHEC_03644 2.6e-81 S Phage Mu protein F like protein
CINOAHEC_03647 5.4e-44 S Phage minor structural protein GP20
CINOAHEC_03648 1.1e-16 gpG
CINOAHEC_03649 1.5e-22 gpG
CINOAHEC_03651 6.4e-29 S Phage gp6-like head-tail connector protein
CINOAHEC_03652 8.2e-28 S Phage head-tail joining protein
CINOAHEC_03653 8.9e-37 S Bacteriophage HK97-gp10, putative tail-component
CINOAHEC_03654 3.8e-29 S Protein of unknown function (DUF3168)
CINOAHEC_03655 8.7e-34 S Phage tail tube protein
CINOAHEC_03656 1.8e-09 chiA 3.2.1.14 GH18 G Glycosyl hydrolases family 18
CINOAHEC_03657 7.1e-28 S Phage tail assembly chaperone protein, TAC
CINOAHEC_03658 1.2e-140
CINOAHEC_03659 2e-50
CINOAHEC_03660 1.1e-222 S peptidoglycan catabolic process
CINOAHEC_03665 1.9e-27 xhlA S Haemolysin XhlA
CINOAHEC_03666 5.1e-30 xhlB S SPP1 phage holin
CINOAHEC_03667 9.8e-104 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
CINOAHEC_03668 9e-41 S protein domain associated with
CINOAHEC_03670 6.1e-27 K Helix-turn-helix domain
CINOAHEC_03671 3.4e-67 rnhA 3.1.26.4 L Caulimovirus viroplasmin
CINOAHEC_03672 4.9e-07 S Antitoxin to bacterial toxin RNase LS or RnlA
CINOAHEC_03673 4.1e-13
CINOAHEC_03674 6.8e-152 ydjC S Abhydrolase domain containing 18
CINOAHEC_03675 0.0 K NB-ARC domain
CINOAHEC_03676 8.5e-201 gutB 1.1.1.14 E Dehydrogenase
CINOAHEC_03677 6.7e-254 gutA G MFS/sugar transport protein
CINOAHEC_03678 7.5e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
CINOAHEC_03679 5.6e-113 pspA KT Phage shock protein A
CINOAHEC_03680 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CINOAHEC_03681 1.6e-137 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
CINOAHEC_03682 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
CINOAHEC_03683 4.7e-196 S Ion transport 2 domain protein
CINOAHEC_03684 2.7e-258 iolT EGP Major facilitator Superfamily
CINOAHEC_03685 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
CINOAHEC_03686 4.5e-64 ydjM M Lytic transglycolase
CINOAHEC_03687 1.5e-152 ydjN U Involved in the tonB-independent uptake of proteins
CINOAHEC_03689 1.4e-34 ydjO S Cold-inducible protein YdjO
CINOAHEC_03690 9.5e-160 ydjP I Alpha/beta hydrolase family
CINOAHEC_03691 1.6e-177 yeaA S Protein of unknown function (DUF4003)
CINOAHEC_03692 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
CINOAHEC_03693 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
CINOAHEC_03694 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CINOAHEC_03695 1.7e-176 yeaC S COG0714 MoxR-like ATPases
CINOAHEC_03696 3.6e-224 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
CINOAHEC_03697 0.0 yebA E COG1305 Transglutaminase-like enzymes
CINOAHEC_03698 7.1e-305 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
CINOAHEC_03699 1e-85 K Belongs to the sigma-70 factor family. ECF subfamily
CINOAHEC_03700 1.7e-252 S Domain of unknown function (DUF4179)
CINOAHEC_03701 5.1e-211 pbuG S permease
CINOAHEC_03702 2.3e-118 yebC M Membrane
CINOAHEC_03704 8.9e-93 yebE S UPF0316 protein
CINOAHEC_03705 8e-28 yebG S NETI protein
CINOAHEC_03706 1.3e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CINOAHEC_03707 1.5e-214 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CINOAHEC_03708 2.1e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CINOAHEC_03709 1.4e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
CINOAHEC_03710 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CINOAHEC_03711 1.9e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CINOAHEC_03712 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CINOAHEC_03713 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CINOAHEC_03714 3.2e-176 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
CINOAHEC_03715 3.7e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CINOAHEC_03716 1.2e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
CINOAHEC_03717 2.2e-232 purD 6.3.4.13 F Belongs to the GARS family
CINOAHEC_03718 1e-72 K helix_turn_helix ASNC type
CINOAHEC_03719 7.3e-231 yjeH E Amino acid permease
CINOAHEC_03720 2.7e-27 S Protein of unknown function (DUF2892)
CINOAHEC_03721 0.0 yerA 3.5.4.2 F adenine deaminase
CINOAHEC_03722 1.3e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
CINOAHEC_03723 4.8e-51 yerC S protein conserved in bacteria
CINOAHEC_03724 2.6e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
CINOAHEC_03726 1.4e-124 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
CINOAHEC_03727 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
CINOAHEC_03728 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CINOAHEC_03729 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
CINOAHEC_03730 5e-195 yerI S homoserine kinase type II (protein kinase fold)
CINOAHEC_03731 8.8e-122 sapB S MgtC SapB transporter
CINOAHEC_03732 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CINOAHEC_03733 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CINOAHEC_03734 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
CINOAHEC_03735 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CINOAHEC_03736 1.3e-146 yerO K Transcriptional regulator
CINOAHEC_03737 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CINOAHEC_03738 5.1e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
CINOAHEC_03739 2e-250 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CINOAHEC_03741 6.9e-100 S response regulator aspartate phosphatase
CINOAHEC_03743 6.3e-40 S Immunity protein 22
CINOAHEC_03744 3.3e-187 yobL S Bacterial EndoU nuclease
CINOAHEC_03745 2e-178 3.4.24.40 CO amine dehydrogenase activity
CINOAHEC_03746 6.7e-39
CINOAHEC_03747 7.9e-213 S Tetratricopeptide repeat
CINOAHEC_03749 2.7e-126 yeeN K transcriptional regulatory protein
CINOAHEC_03751 3.6e-100 dhaR3 K Transcriptional regulator
CINOAHEC_03752 8.2e-81 yesE S SnoaL-like domain
CINOAHEC_03753 1.3e-151 yesF GM NAD(P)H-binding
CINOAHEC_03754 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
CINOAHEC_03755 1.5e-45 cotJB S CotJB protein
CINOAHEC_03756 5.2e-104 cotJC P Spore Coat
CINOAHEC_03757 6e-102 yesJ K Acetyltransferase (GNAT) family
CINOAHEC_03759 3.1e-102 yesL S Protein of unknown function, DUF624
CINOAHEC_03760 0.0 yesM 2.7.13.3 T Histidine kinase
CINOAHEC_03761 1e-201 yesN K helix_turn_helix, arabinose operon control protein
CINOAHEC_03762 8e-246 yesO G Bacterial extracellular solute-binding protein
CINOAHEC_03763 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
CINOAHEC_03764 1.2e-163 yesQ P Binding-protein-dependent transport system inner membrane component
CINOAHEC_03765 2.3e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
CINOAHEC_03766 0.0 yesS K Transcriptional regulator
CINOAHEC_03767 4.4e-129 E GDSL-like Lipase/Acylhydrolase
CINOAHEC_03768 6e-128 yesU S Domain of unknown function (DUF1961)
CINOAHEC_03769 1.3e-111 yesV S Protein of unknown function, DUF624
CINOAHEC_03770 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
CINOAHEC_03771 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
CINOAHEC_03773 1.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
CINOAHEC_03774 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
CINOAHEC_03775 0.0 yetA
CINOAHEC_03776 2.8e-290 lplA G Bacterial extracellular solute-binding protein
CINOAHEC_03777 1.5e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
CINOAHEC_03778 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
CINOAHEC_03779 4.9e-254 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
CINOAHEC_03780 8.8e-122 yetF S membrane
CINOAHEC_03781 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
CINOAHEC_03782 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CINOAHEC_03783 2.2e-34
CINOAHEC_03784 5.4e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CINOAHEC_03785 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
CINOAHEC_03786 5.3e-105 yetJ S Belongs to the BI1 family
CINOAHEC_03787 1.4e-89 yetL K helix_turn_helix multiple antibiotic resistance protein
CINOAHEC_03788 4e-209 yetM CH FAD binding domain
CINOAHEC_03789 1.6e-133 M Membrane
CINOAHEC_03790 3.7e-196 yetN S Protein of unknown function (DUF3900)
CINOAHEC_03791 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
CINOAHEC_03792 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
CINOAHEC_03793 2.1e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
CINOAHEC_03794 1.9e-172 yfnG 4.2.1.45 M dehydratase
CINOAHEC_03795 1.6e-179 yfnF M Nucleotide-diphospho-sugar transferase
CINOAHEC_03796 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
CINOAHEC_03797 1e-189 yfnD M Nucleotide-diphospho-sugar transferase
CINOAHEC_03798 4.6e-206 fsr P COG0477 Permeases of the major facilitator superfamily
CINOAHEC_03799 5.6e-132 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
CINOAHEC_03800 8.4e-241 yfnA E amino acid
CINOAHEC_03801 2.8e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CINOAHEC_03802 1.1e-113 yfmS NT chemotaxis protein
CINOAHEC_03803 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
CINOAHEC_03804 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
CINOAHEC_03805 2.8e-70 yfmP K transcriptional
CINOAHEC_03806 4.3e-209 yfmO EGP Major facilitator Superfamily
CINOAHEC_03807 1.9e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
CINOAHEC_03808 2.9e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
CINOAHEC_03809 3.1e-80 yfmK 2.3.1.128 K acetyltransferase
CINOAHEC_03810 9.4e-189 yfmJ S N-terminal domain of oxidoreductase
CINOAHEC_03811 7.7e-214 G Major Facilitator Superfamily
CINOAHEC_03812 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
CINOAHEC_03813 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
CINOAHEC_03814 2e-167 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CINOAHEC_03815 4.7e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CINOAHEC_03816 1.7e-168 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
CINOAHEC_03817 2.9e-24 S Protein of unknown function (DUF3212)
CINOAHEC_03818 7.6e-58 yflT S Heat induced stress protein YflT
CINOAHEC_03819 2.5e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
CINOAHEC_03820 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
CINOAHEC_03821 5.3e-287 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
CINOAHEC_03822 8.9e-119 citT T response regulator
CINOAHEC_03823 2.8e-179 yflP S Tripartite tricarboxylate transporter family receptor
CINOAHEC_03824 8.5e-227 citM C Citrate transporter
CINOAHEC_03825 3.9e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
CINOAHEC_03826 8.7e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CINOAHEC_03827 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
CINOAHEC_03828 9.9e-123 yflK S protein conserved in bacteria
CINOAHEC_03829 4e-18 yflJ S Protein of unknown function (DUF2639)
CINOAHEC_03830 4.1e-19 yflI
CINOAHEC_03831 5.3e-50 yflH S Protein of unknown function (DUF3243)
CINOAHEC_03832 4.2e-138 map 3.4.11.18 E Methionine aminopeptidase
CINOAHEC_03833 3.3e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
CINOAHEC_03834 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
CINOAHEC_03835 6e-67 yhdN S Domain of unknown function (DUF1992)
CINOAHEC_03836 2.8e-252 agcS_1 E Sodium alanine symporter
CINOAHEC_03837 3e-193 E Spore germination protein
CINOAHEC_03839 3.3e-206 yfkR S spore germination
CINOAHEC_03840 4.9e-282 yfkQ EG Spore germination protein
CINOAHEC_03841 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CINOAHEC_03842 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
CINOAHEC_03843 1.8e-133 treR K transcriptional
CINOAHEC_03844 1.1e-124 yfkO C nitroreductase
CINOAHEC_03845 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
CINOAHEC_03846 9.6e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
CINOAHEC_03847 5.8e-206 ydiM EGP Major facilitator Superfamily
CINOAHEC_03848 3.5e-29 yfkK S Belongs to the UPF0435 family
CINOAHEC_03849 1.9e-83 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CINOAHEC_03850 7.1e-50 yfkI S gas vesicle protein
CINOAHEC_03851 1.3e-143 yihY S Belongs to the UPF0761 family
CINOAHEC_03852 5e-08
CINOAHEC_03853 3.4e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
CINOAHEC_03854 6.1e-183 cax P COG0387 Ca2 H antiporter
CINOAHEC_03855 1.2e-146 yfkD S YfkD-like protein
CINOAHEC_03856 7.8e-149 yfkC M Mechanosensitive ion channel
CINOAHEC_03857 5.4e-222 yfkA S YfkB-like domain
CINOAHEC_03858 1.1e-26 yfjT
CINOAHEC_03859 1.7e-153 pdaA G deacetylase
CINOAHEC_03860 1.6e-149 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
CINOAHEC_03861 1.7e-184 corA P Mediates influx of magnesium ions
CINOAHEC_03862 1.3e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CINOAHEC_03863 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CINOAHEC_03864 6.7e-44 S YfzA-like protein
CINOAHEC_03865 1.1e-186 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CINOAHEC_03866 1.9e-85 yfjM S Psort location Cytoplasmic, score
CINOAHEC_03867 2.6e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
CINOAHEC_03868 2.1e-188 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
CINOAHEC_03869 2.4e-196 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CINOAHEC_03870 2.3e-251 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
CINOAHEC_03871 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
CINOAHEC_03872 1.2e-25 sspH S Belongs to the SspH family
CINOAHEC_03873 1.2e-55 yfjF S UPF0060 membrane protein
CINOAHEC_03874 1.4e-85 S Family of unknown function (DUF5381)
CINOAHEC_03875 2.3e-123 yfjC
CINOAHEC_03876 9.6e-172 yfjB
CINOAHEC_03877 1.7e-43 yfjA S Belongs to the WXG100 family
CINOAHEC_03878 9.9e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
CINOAHEC_03879 3.2e-141 glvR K Helix-turn-helix domain, rpiR family
CINOAHEC_03880 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CINOAHEC_03881 2.1e-310 yfiB3 V ABC transporter
CINOAHEC_03882 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
CINOAHEC_03883 9.8e-65 mhqP S DoxX
CINOAHEC_03884 5.7e-163 yfiE 1.13.11.2 S glyoxalase
CINOAHEC_03886 3.4e-211 yxjM T Histidine kinase
CINOAHEC_03887 5.4e-113 KT LuxR family transcriptional regulator
CINOAHEC_03888 5.2e-170 V ABC transporter, ATP-binding protein
CINOAHEC_03889 1.7e-205 V ABC-2 family transporter protein
CINOAHEC_03890 3.8e-202 V COG0842 ABC-type multidrug transport system, permease component
CINOAHEC_03891 8.3e-99 padR K transcriptional
CINOAHEC_03892 1.7e-79 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
CINOAHEC_03893 2.9e-196 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
CINOAHEC_03894 3.1e-98 yfiT S Belongs to the metal hydrolase YfiT family
CINOAHEC_03895 3.4e-283 yfiU EGP Major facilitator Superfamily
CINOAHEC_03896 2.2e-79 yfiV K transcriptional
CINOAHEC_03897 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CINOAHEC_03898 3.7e-166 yfiY P ABC transporter substrate-binding protein
CINOAHEC_03899 3.1e-176 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CINOAHEC_03900 2.9e-169 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CINOAHEC_03901 1.6e-165 yfhB 5.3.3.17 S PhzF family
CINOAHEC_03902 3.9e-107 yfhC C nitroreductase
CINOAHEC_03903 2.1e-25 yfhD S YfhD-like protein
CINOAHEC_03905 6e-171 yfhF S nucleoside-diphosphate sugar epimerase
CINOAHEC_03906 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
CINOAHEC_03907 9.7e-52 yfhH S Protein of unknown function (DUF1811)
CINOAHEC_03908 2.5e-209 yfhI EGP Major facilitator Superfamily
CINOAHEC_03909 9e-19 sspK S reproduction
CINOAHEC_03910 1.3e-44 yfhJ S WVELL protein
CINOAHEC_03911 2.1e-88 batE T Bacterial SH3 domain homologues
CINOAHEC_03912 3.5e-51 yfhL S SdpI/YhfL protein family
CINOAHEC_03913 3.1e-169 yfhM S Alpha beta hydrolase
CINOAHEC_03914 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
CINOAHEC_03915 0.0 yfhO S Bacterial membrane protein YfhO
CINOAHEC_03916 5.5e-186 yfhP S membrane-bound metal-dependent
CINOAHEC_03917 7.8e-212 mutY L A G-specific
CINOAHEC_03918 2.6e-35 yfhS
CINOAHEC_03919 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CINOAHEC_03920 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
CINOAHEC_03921 1.5e-37 ygaB S YgaB-like protein
CINOAHEC_03922 1.3e-104 ygaC J Belongs to the UPF0374 family
CINOAHEC_03923 1.8e-301 ygaD V ABC transporter
CINOAHEC_03924 8.7e-180 ygaE S Membrane
CINOAHEC_03925 4e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
CINOAHEC_03926 6.3e-87 bcp 1.11.1.15 O Peroxiredoxin
CINOAHEC_03927 4e-80 perR P Belongs to the Fur family
CINOAHEC_03928 2.8e-55 ygzB S UPF0295 protein
CINOAHEC_03929 1.5e-166 ygxA S Nucleotidyltransferase-like
CINOAHEC_03930 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CINOAHEC_03931 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
CINOAHEC_03932 7.5e-140 srfAD Q thioesterase
CINOAHEC_03933 7e-223 EGP Major Facilitator Superfamily
CINOAHEC_03934 3.3e-87 S YcxB-like protein
CINOAHEC_03935 6.4e-160 ycxC EG EamA-like transporter family
CINOAHEC_03936 6.6e-53 ycxD K GntR family transcriptional regulator
CINOAHEC_03937 1.1e-175 ycxD K GntR family transcriptional regulator
CINOAHEC_03938 2.9e-114 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
CINOAHEC_03939 1.7e-114 yczE S membrane
CINOAHEC_03940 4.1e-133 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
CINOAHEC_03941 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
CINOAHEC_03942 3.4e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
CINOAHEC_03943 1.9e-161 bsdA K LysR substrate binding domain
CINOAHEC_03944 7.6e-109 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
CINOAHEC_03945 4.1e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
CINOAHEC_03946 4e-39 bsdD 4.1.1.61 S response to toxic substance
CINOAHEC_03947 2.5e-80 yclD
CINOAHEC_03948 2.2e-159 yclE 3.4.11.5 S Alpha beta hydrolase
CINOAHEC_03949 5.2e-265 dtpT E amino acid peptide transporter
CINOAHEC_03950 4.1e-309 yclG M Pectate lyase superfamily protein
CINOAHEC_03952 1.5e-281 gerKA EG Spore germination protein
CINOAHEC_03953 1.3e-232 gerKC S spore germination
CINOAHEC_03954 1.7e-199 gerKB F Spore germination protein
CINOAHEC_03955 1.9e-121 yclH P ABC transporter
CINOAHEC_03956 1.5e-203 yclI V ABC transporter (permease) YclI
CINOAHEC_03957 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CINOAHEC_03958 1.5e-261 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
CINOAHEC_03959 2e-70 S aspartate phosphatase
CINOAHEC_03963 8.3e-241 lysC 2.7.2.4 E Belongs to the aspartokinase family
CINOAHEC_03964 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CINOAHEC_03965 6.3e-163 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CINOAHEC_03966 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
CINOAHEC_03967 1.2e-166 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
CINOAHEC_03968 3.2e-251 ycnB EGP Major facilitator Superfamily
CINOAHEC_03969 2.7e-152 ycnC K Transcriptional regulator
CINOAHEC_03970 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
CINOAHEC_03971 1.6e-45 ycnE S Monooxygenase
CINOAHEC_03972 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
CINOAHEC_03973 1.3e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CINOAHEC_03974 4.4e-247 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CINOAHEC_03975 3.4e-266 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CINOAHEC_03976 6.1e-149 glcU U Glucose uptake
CINOAHEC_03977 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CINOAHEC_03978 1.3e-100 ycnI S protein conserved in bacteria
CINOAHEC_03979 1.4e-308 ycnJ P protein, homolog of Cu resistance protein CopC
CINOAHEC_03980 1.7e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
CINOAHEC_03981 7.3e-56
CINOAHEC_03982 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
CINOAHEC_03983 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
CINOAHEC_03984 1.8e-209 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
CINOAHEC_03985 1.4e-200 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
CINOAHEC_03986 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
CINOAHEC_03987 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
CINOAHEC_03988 1.4e-110 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
CINOAHEC_03989 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
CINOAHEC_03991 3e-136 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
CINOAHEC_03992 8e-140 ycsF S Belongs to the UPF0271 (lamB) family
CINOAHEC_03993 1.6e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
CINOAHEC_03994 4.8e-148 ycsI S Belongs to the D-glutamate cyclase family
CINOAHEC_03995 1.9e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
CINOAHEC_03996 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
CINOAHEC_03997 1.2e-132 kipR K Transcriptional regulator
CINOAHEC_03998 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
CINOAHEC_04000 1.4e-49 yczJ S biosynthesis
CINOAHEC_04001 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
CINOAHEC_04002 8.3e-173 ydhF S Oxidoreductase
CINOAHEC_04003 0.0 mtlR K transcriptional regulator, MtlR
CINOAHEC_04004 1.5e-291 ydaB IQ acyl-CoA ligase
CINOAHEC_04005 1.7e-97 ydaC Q Methyltransferase domain
CINOAHEC_04006 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CINOAHEC_04007 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
CINOAHEC_04008 6.1e-102 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
CINOAHEC_04009 6.8e-77 ydaG 1.4.3.5 S general stress protein
CINOAHEC_04010 5.4e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
CINOAHEC_04011 3.3e-46 ydzA EGP Major facilitator Superfamily
CINOAHEC_04012 2.5e-74 lrpC K Transcriptional regulator
CINOAHEC_04013 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CINOAHEC_04014 1.2e-205 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
CINOAHEC_04015 1.3e-151 ydaK T Diguanylate cyclase, GGDEF domain
CINOAHEC_04016 4e-44 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
CINOAHEC_04017 6.2e-246 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
CINOAHEC_04018 4.5e-233 ydaM M Glycosyl transferase family group 2
CINOAHEC_04019 0.0 ydaN S Bacterial cellulose synthase subunit
CINOAHEC_04020 0.0 ydaO E amino acid
CINOAHEC_04021 1.1e-77 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
CINOAHEC_04022 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
CINOAHEC_04023 9.4e-40
CINOAHEC_04024 1.3e-224 mntH P H( )-stimulated, divalent metal cation uptake system
CINOAHEC_04026 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
CINOAHEC_04027 3.2e-147 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
CINOAHEC_04029 1.5e-55 ydbB G Cupin domain
CINOAHEC_04030 1.3e-60 ydbC S Domain of unknown function (DUF4937
CINOAHEC_04031 3.5e-154 ydbD P Catalase
CINOAHEC_04032 2.7e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
CINOAHEC_04033 1.3e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
CINOAHEC_04034 1.1e-119 dctR T COG4565 Response regulator of citrate malate metabolism
CINOAHEC_04035 1.1e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CINOAHEC_04036 1.4e-179 ydbI S AI-2E family transporter
CINOAHEC_04037 1.3e-168 ydbJ V ABC transporter, ATP-binding protein
CINOAHEC_04038 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
CINOAHEC_04039 2.7e-52 ydbL
CINOAHEC_04040 1.5e-219 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
CINOAHEC_04041 1.1e-18 S Fur-regulated basic protein B
CINOAHEC_04042 1.7e-07 S Fur-regulated basic protein A
CINOAHEC_04043 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CINOAHEC_04044 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
CINOAHEC_04045 3.9e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
CINOAHEC_04046 3.5e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
CINOAHEC_04047 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
CINOAHEC_04048 2.1e-82 ydbS S Bacterial PH domain
CINOAHEC_04049 2.2e-263 ydbT S Membrane
CINOAHEC_04050 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
CINOAHEC_04051 2.5e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
CINOAHEC_04052 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
CINOAHEC_04053 2.3e-223 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CINOAHEC_04054 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
CINOAHEC_04055 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
CINOAHEC_04056 1.3e-143 rsbR T Positive regulator of sigma-B
CINOAHEC_04057 1.5e-56 rsbS T antagonist
CINOAHEC_04058 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
CINOAHEC_04059 7.1e-189 rsbU 3.1.3.3 KT phosphatase
CINOAHEC_04060 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
CINOAHEC_04061 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
CINOAHEC_04062 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CINOAHEC_04063 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
CINOAHEC_04064 0.0 yhgF K COG2183 Transcriptional accessory protein
CINOAHEC_04065 8.9e-83 ydcK S Belongs to the SprT family
CINOAHEC_04074 3.4e-33 K Helix-turn-helix XRE-family like proteins
CINOAHEC_04075 1.2e-39
CINOAHEC_04079 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
CINOAHEC_04080 8.7e-30 cspL K Cold shock
CINOAHEC_04081 2.3e-78 carD K Transcription factor
CINOAHEC_04082 3.3e-142 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
CINOAHEC_04083 3.6e-165 rhaS5 K AraC-like ligand binding domain
CINOAHEC_04084 8.3e-171 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
CINOAHEC_04085 2.6e-163 ydeE K AraC family transcriptional regulator
CINOAHEC_04086 2.4e-259 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CINOAHEC_04087 1.2e-217 ydeG EGP Major facilitator superfamily
CINOAHEC_04088 1.4e-44 ydeH
CINOAHEC_04089 3.9e-102 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
CINOAHEC_04090 3.8e-103
CINOAHEC_04091 1.8e-14 ptsH G PTS HPr component phosphorylation site
CINOAHEC_04092 3.4e-84 K Transcriptional regulator C-terminal region
CINOAHEC_04093 1.3e-151 ydeK EG -transporter
CINOAHEC_04094 6e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CINOAHEC_04095 7.1e-74 maoC I N-terminal half of MaoC dehydratase
CINOAHEC_04096 2.5e-104 ydeN S Serine hydrolase
CINOAHEC_04097 1.2e-55 K HxlR-like helix-turn-helix
CINOAHEC_04098 2.1e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
CINOAHEC_04099 9.6e-185 ydeR EGP Major facilitator Superfamily
CINOAHEC_04100 3.2e-104 ydeS K Transcriptional regulator
CINOAHEC_04102 2.8e-57 arsR K transcriptional
CINOAHEC_04103 5.2e-232 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CINOAHEC_04104 1.8e-144 ydfB J GNAT acetyltransferase
CINOAHEC_04105 1.6e-158 ydfC EG EamA-like transporter family
CINOAHEC_04106 2.3e-273 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CINOAHEC_04107 1.4e-115 ydfE S Flavin reductase like domain
CINOAHEC_04108 3.9e-122 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
CINOAHEC_04109 3.4e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CINOAHEC_04110 7.7e-179 ydfH 2.7.13.3 T Histidine kinase
CINOAHEC_04111 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CINOAHEC_04112 0.0 ydfJ S drug exporters of the RND superfamily
CINOAHEC_04113 3.1e-175 S Alpha/beta hydrolase family
CINOAHEC_04114 8.5e-117 S Protein of unknown function (DUF554)
CINOAHEC_04115 6.6e-145 K Bacterial transcription activator, effector binding domain
CINOAHEC_04116 1.7e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CINOAHEC_04117 4e-110 ydfN C nitroreductase
CINOAHEC_04118 1.7e-184 ydfO E COG0346 Lactoylglutathione lyase and related lyases
CINOAHEC_04119 8.8e-63 mhqP S DoxX
CINOAHEC_04120 1.6e-55 traF CO Thioredoxin
CINOAHEC_04121 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
CINOAHEC_04122 6.3e-29
CINOAHEC_04124 4.4e-118 ydfR S Protein of unknown function (DUF421)
CINOAHEC_04125 9e-122 ydfS S Protein of unknown function (DUF421)
CINOAHEC_04126 2.2e-75 cotP O Belongs to the small heat shock protein (HSP20) family
CINOAHEC_04127 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
CINOAHEC_04128 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
CINOAHEC_04129 2.2e-97 K Bacterial regulatory proteins, tetR family
CINOAHEC_04130 9e-51 S DoxX-like family
CINOAHEC_04131 4.7e-52 yycN 2.3.1.128 K Acetyltransferase
CINOAHEC_04132 1e-301 expZ S ABC transporter
CINOAHEC_04133 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
CINOAHEC_04134 1.1e-89 dinB S DinB family
CINOAHEC_04135 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
CINOAHEC_04136 0.0 ydgH S drug exporters of the RND superfamily
CINOAHEC_04137 8.8e-113 drgA C nitroreductase
CINOAHEC_04138 7.1e-69 ydgJ K Winged helix DNA-binding domain
CINOAHEC_04139 2.2e-208 tcaB EGP Major facilitator Superfamily
CINOAHEC_04140 3.5e-121 ydhB S membrane transporter protein
CINOAHEC_04141 6.5e-122 ydhC K FCD
CINOAHEC_04142 1.1e-242 ydhD M Glycosyl hydrolase
CINOAHEC_04143 1.6e-227 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
CINOAHEC_04144 1.9e-124
CINOAHEC_04145 2.6e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
CINOAHEC_04146 8.7e-68 frataxin S Domain of unknown function (DU1801)
CINOAHEC_04148 1.9e-83 K Acetyltransferase (GNAT) domain
CINOAHEC_04149 1.1e-178 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
CINOAHEC_04150 2.8e-97 ydhK M Protein of unknown function (DUF1541)
CINOAHEC_04151 1.3e-199 pbuE EGP Major facilitator Superfamily
CINOAHEC_04152 1.9e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
CINOAHEC_04153 3e-51 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
CINOAHEC_04154 1.7e-238 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CINOAHEC_04155 5.8e-282 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CINOAHEC_04156 1.1e-132 ydhQ K UTRA
CINOAHEC_04157 2.2e-165 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
CINOAHEC_04158 5.6e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
CINOAHEC_04159 2.9e-212 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
CINOAHEC_04160 2.3e-156 ydhU P Catalase
CINOAHEC_04165 1.3e-63 hxlR K transcriptional
CINOAHEC_04166 3.6e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
CINOAHEC_04167 1.8e-96 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
CINOAHEC_04168 3.9e-187 tlpC 2.7.13.3 NT chemotaxis protein
CINOAHEC_04169 3e-70 nucA M Deoxyribonuclease NucA/NucB
CINOAHEC_04170 6.5e-69 nin S Competence protein J (ComJ)
CINOAHEC_04171 4e-294 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CINOAHEC_04172 7.8e-52 yckD S Protein of unknown function (DUF2680)
CINOAHEC_04173 3.3e-45 yckC S membrane
CINOAHEC_04174 7.5e-131 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
CINOAHEC_04175 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
CINOAHEC_04176 1.4e-228 yciC S GTPases (G3E family)
CINOAHEC_04177 7.9e-108 yciB M ErfK YbiS YcfS YnhG
CINOAHEC_04178 4.3e-169 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
CINOAHEC_04179 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
CINOAHEC_04180 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
CINOAHEC_04181 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CINOAHEC_04182 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CINOAHEC_04183 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
CINOAHEC_04184 3.2e-275 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
CINOAHEC_04185 2.4e-192 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
CINOAHEC_04186 1.6e-157 I alpha/beta hydrolase fold
CINOAHEC_04187 9.1e-140 ycgR S permeases
CINOAHEC_04188 9.1e-145 ycgQ S membrane
CINOAHEC_04189 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
CINOAHEC_04190 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CINOAHEC_04191 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
CINOAHEC_04192 1.1e-169 ycgM E Proline dehydrogenase
CINOAHEC_04193 2.9e-145 ycgL S Predicted nucleotidyltransferase
CINOAHEC_04194 4.2e-183 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
CINOAHEC_04195 1.2e-177 oxyR3 K LysR substrate binding domain
CINOAHEC_04196 1.7e-142 yafE Q ubiE/COQ5 methyltransferase family
CINOAHEC_04197 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CINOAHEC_04198 2.5e-109 tmrB S AAA domain
CINOAHEC_04199 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
CINOAHEC_04200 2.4e-112 ycgI S Domain of unknown function (DUF1989)
CINOAHEC_04201 1.4e-248 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
CINOAHEC_04202 1.2e-151 yqcI S YqcI/YcgG family
CINOAHEC_04203 6.8e-113 ycgF E Lysine exporter protein LysE YggA
CINOAHEC_04204 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
CINOAHEC_04205 6.2e-269 mdr EGP Major facilitator Superfamily
CINOAHEC_04206 6.5e-293 lctP C L-lactate permease
CINOAHEC_04207 3.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
CINOAHEC_04208 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
CINOAHEC_04209 1.1e-98 ycgB
CINOAHEC_04210 3.3e-256 ycgA S Membrane
CINOAHEC_04211 1.1e-217 amhX S amidohydrolase
CINOAHEC_04212 1.5e-163 opuAC E glycine betaine
CINOAHEC_04213 1.3e-127 opuAB P glycine betaine
CINOAHEC_04214 5.1e-229 proV 3.6.3.32 E glycine betaine
CINOAHEC_04215 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
CINOAHEC_04216 3.2e-162 yceJ EGP Uncharacterised MFS-type transporter YbfB
CINOAHEC_04217 6.6e-218 naiP P Uncharacterised MFS-type transporter YbfB
CINOAHEC_04218 2e-192 yceH P Belongs to the TelA family
CINOAHEC_04219 0.0 yceG S Putative component of 'biosynthetic module'
CINOAHEC_04220 1.4e-136 terC P Protein of unknown function (DUF475)
CINOAHEC_04221 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
CINOAHEC_04222 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
CINOAHEC_04223 5.1e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
CINOAHEC_04224 4.2e-186 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CINOAHEC_04225 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
CINOAHEC_04226 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
CINOAHEC_04227 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
CINOAHEC_04228 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
CINOAHEC_04229 4.7e-140 IQ Enoyl-(Acyl carrier protein) reductase
CINOAHEC_04230 5.5e-174 S response regulator aspartate phosphatase
CINOAHEC_04231 1.7e-95 cwlK M D-alanyl-D-alanine carboxypeptidase
CINOAHEC_04232 6.7e-268 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
CINOAHEC_04233 5.9e-282 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
CINOAHEC_04234 6.6e-177 ycdA S Domain of unknown function (DUF5105)
CINOAHEC_04235 4.6e-174 yccK C Aldo keto reductase
CINOAHEC_04236 4.5e-203 natB CP ABC-2 family transporter protein
CINOAHEC_04237 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
CINOAHEC_04238 1.2e-126 lytR_2 T LytTr DNA-binding domain
CINOAHEC_04239 5.6e-159 2.7.13.3 T GHKL domain
CINOAHEC_04240 3.6e-199 yccF K DNA-templated transcriptional preinitiation complex assembly
CINOAHEC_04241 3.4e-59 S RDD family
CINOAHEC_04242 4.7e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
CINOAHEC_04243 5.3e-201 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
CINOAHEC_04244 7e-101 yxaF K Transcriptional regulator
CINOAHEC_04245 7.9e-226 lmrB EGP the major facilitator superfamily
CINOAHEC_04246 6.6e-204 ycbU E Selenocysteine lyase
CINOAHEC_04247 1.7e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CINOAHEC_04248 1.7e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CINOAHEC_04249 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
CINOAHEC_04250 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
CINOAHEC_04251 9.5e-135 ycbR T vWA found in TerF C terminus
CINOAHEC_04252 2.2e-78 sleB 3.5.1.28 M Cell wall
CINOAHEC_04253 1.2e-51 ycbP S Protein of unknown function (DUF2512)
CINOAHEC_04254 7.4e-113 S ABC-2 family transporter protein
CINOAHEC_04255 5e-165 ycbN V ABC transporter, ATP-binding protein
CINOAHEC_04256 5.4e-167 T PhoQ Sensor
CINOAHEC_04257 1.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CINOAHEC_04258 3.8e-168 eamA1 EG spore germination
CINOAHEC_04259 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
CINOAHEC_04260 3.1e-175 ycbJ S Macrolide 2'-phosphotransferase
CINOAHEC_04261 4.5e-296 garD 4.2.1.42, 4.2.1.7 G Altronate
CINOAHEC_04262 2.1e-123 ycbG K FCD
CINOAHEC_04263 2.2e-270 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
CINOAHEC_04264 1.2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
CINOAHEC_04265 3.7e-274 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CINOAHEC_04266 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
CINOAHEC_04267 9e-170 glnL T Regulator
CINOAHEC_04268 1.5e-229 phoQ 2.7.13.3 T Histidine kinase
CINOAHEC_04269 1.5e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
CINOAHEC_04270 2.8e-255 agcS E Sodium alanine symporter
CINOAHEC_04271 6.7e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
CINOAHEC_04272 7.5e-261 mmuP E amino acid
CINOAHEC_04273 4.6e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
CINOAHEC_04275 4.9e-128 K UTRA
CINOAHEC_04276 8e-137 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CINOAHEC_04277 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CINOAHEC_04278 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CINOAHEC_04279 8.6e-192 yceA S Belongs to the UPF0176 family
CINOAHEC_04280 2.1e-252 S Erythromycin esterase
CINOAHEC_04281 1.3e-44 ybfN
CINOAHEC_04282 8.1e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
CINOAHEC_04283 2.7e-85 ybfM S SNARE associated Golgi protein
CINOAHEC_04284 9.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CINOAHEC_04285 1.8e-167 S Alpha/beta hydrolase family
CINOAHEC_04287 1.5e-177 mpr 3.4.21.19 M Belongs to the peptidase S1B family
CINOAHEC_04288 2.3e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CINOAHEC_04289 9.7e-144 msmR K AraC-like ligand binding domain
CINOAHEC_04290 2.6e-161 ybfH EG EamA-like transporter family
CINOAHEC_04291 2.5e-223 ybfB G COG0477 Permeases of the major facilitator superfamily
CINOAHEC_04292 2.2e-168 ybfA 3.4.15.5 K FR47-like protein
CINOAHEC_04293 1.5e-34 S Protein of unknown function (DUF2651)
CINOAHEC_04294 7.3e-258 glpT G -transporter
CINOAHEC_04295 1.8e-159 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
CINOAHEC_04296 4.1e-49 M PFAM Glycosyl transferase family 2
CINOAHEC_04297 8.8e-290 ybeC E amino acid
CINOAHEC_04298 4.9e-41 ybyB
CINOAHEC_04299 7.6e-241 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
CINOAHEC_04300 1.5e-149 ybxI 3.5.2.6 V beta-lactamase
CINOAHEC_04301 5.4e-29 ybxH S Family of unknown function (DUF5370)
CINOAHEC_04302 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
CINOAHEC_04303 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
CINOAHEC_04304 4.4e-214 ybdO S Domain of unknown function (DUF4885)
CINOAHEC_04305 1.7e-151 ybdN
CINOAHEC_04306 8.8e-139 KLT Protein tyrosine kinase
CINOAHEC_04308 2.9e-171 T His Kinase A (phospho-acceptor) domain
CINOAHEC_04309 3.5e-98 T Transcriptional regulatory protein, C terminal
CINOAHEC_04310 1.4e-181 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
CINOAHEC_04311 1.4e-144 msbA2 3.6.3.44 V ABC transporter
CINOAHEC_04313 3.7e-60 spaC1 V Lanthionine synthetase C-like protein
CINOAHEC_04314 2.5e-123 spaB S Lantibiotic dehydratase, C terminus
CINOAHEC_04315 2.8e-33 O Subtilase family
CINOAHEC_04317 2.9e-202 ybcL EGP Major facilitator Superfamily
CINOAHEC_04318 9.6e-49 ybzH K Helix-turn-helix domain
CINOAHEC_04319 3.2e-59 ybcI S Uncharacterized conserved protein (DUF2294)
CINOAHEC_04320 1.9e-46
CINOAHEC_04321 3e-90 can 4.2.1.1 P carbonic anhydrase
CINOAHEC_04322 0.0 ybcC S Belongs to the UPF0753 family
CINOAHEC_04323 2.3e-276 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
CINOAHEC_04324 2.5e-100 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CINOAHEC_04325 5.8e-120 adaA 3.2.2.21 K Transcriptional regulator
CINOAHEC_04326 7.9e-171 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CINOAHEC_04327 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
CINOAHEC_04328 9.3e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CINOAHEC_04329 3e-225 ybbR S protein conserved in bacteria
CINOAHEC_04330 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CINOAHEC_04331 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
CINOAHEC_04332 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
CINOAHEC_04338 8.2e-10 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
CINOAHEC_04339 1.3e-57 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
CINOAHEC_04340 1.9e-86 ybbJ J acetyltransferase
CINOAHEC_04341 1.4e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CINOAHEC_04342 5.1e-148 ybbH K transcriptional
CINOAHEC_04343 1.7e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CINOAHEC_04344 5.9e-252 yfeW 3.4.16.4 V Belongs to the UPF0214 family
CINOAHEC_04345 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
CINOAHEC_04346 4.9e-240 ybbC 3.2.1.52 S protein conserved in bacteria
CINOAHEC_04347 7.7e-307 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
CINOAHEC_04348 1.4e-165 feuA P Iron-uptake system-binding protein
CINOAHEC_04349 3.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CINOAHEC_04350 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CINOAHEC_04351 4.1e-141 ybbA S Putative esterase
CINOAHEC_04352 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
CINOAHEC_04353 1.5e-248 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
CINOAHEC_04355 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
CINOAHEC_04356 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
CINOAHEC_04357 1.2e-84 gerD
CINOAHEC_04358 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
CINOAHEC_04359 2.5e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
CINOAHEC_04360 9.1e-64 ybaK S Protein of unknown function (DUF2521)
CINOAHEC_04361 2.4e-144 ybaJ Q Methyltransferase domain
CINOAHEC_04362 1.8e-63 rpsI J Belongs to the universal ribosomal protein uS9 family
CINOAHEC_04363 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CINOAHEC_04364 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CINOAHEC_04365 3e-118 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CINOAHEC_04366 2.6e-152 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CINOAHEC_04367 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CINOAHEC_04368 3.6e-58 rplQ J Ribosomal protein L17
CINOAHEC_04369 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CINOAHEC_04370 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CINOAHEC_04371 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CINOAHEC_04372 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
CINOAHEC_04373 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CINOAHEC_04374 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
CINOAHEC_04375 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
CINOAHEC_04376 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
CINOAHEC_04377 1.8e-72 rplO J binds to the 23S rRNA
CINOAHEC_04378 1.9e-23 rpmD J Ribosomal protein L30
CINOAHEC_04379 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CINOAHEC_04380 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CINOAHEC_04381 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CINOAHEC_04382 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CINOAHEC_04383 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CINOAHEC_04384 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CINOAHEC_04385 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CINOAHEC_04386 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CINOAHEC_04387 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CINOAHEC_04388 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
CINOAHEC_04389 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CINOAHEC_04390 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CINOAHEC_04391 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CINOAHEC_04392 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CINOAHEC_04393 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CINOAHEC_04394 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
CINOAHEC_04395 3e-105 rplD J Forms part of the polypeptide exit tunnel
CINOAHEC_04396 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CINOAHEC_04397 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
CINOAHEC_04398 3.1e-178 ybaC 3.4.11.5 S Alpha/beta hydrolase family
CINOAHEC_04399 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CINOAHEC_04400 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CINOAHEC_04401 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
CINOAHEC_04402 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CINOAHEC_04403 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
CINOAHEC_04404 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CINOAHEC_04405 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CINOAHEC_04406 3.1e-107 rsmC 2.1.1.172 J Methyltransferase
CINOAHEC_04407 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
CINOAHEC_04408 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CINOAHEC_04409 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
CINOAHEC_04410 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CINOAHEC_04411 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
CINOAHEC_04412 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
CINOAHEC_04413 4.4e-115 sigH K Belongs to the sigma-70 factor family
CINOAHEC_04414 1.2e-88 yacP S RNA-binding protein containing a PIN domain
CINOAHEC_04415 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CINOAHEC_04416 1.2e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CINOAHEC_04417 2.1e-271 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
CINOAHEC_04418 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
CINOAHEC_04419 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CINOAHEC_04420 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
CINOAHEC_04421 1.5e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
CINOAHEC_04422 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
CINOAHEC_04423 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CINOAHEC_04424 3.6e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CINOAHEC_04425 0.0 clpC O Belongs to the ClpA ClpB family
CINOAHEC_04426 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
CINOAHEC_04427 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
CINOAHEC_04428 2.9e-76 ctsR K Belongs to the CtsR family
CINOAHEC_04429 3.4e-31 csfB S Inhibitor of sigma-G Gin
CINOAHEC_04430 2.4e-102 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
CINOAHEC_04431 9.9e-203 yaaN P Belongs to the TelA family
CINOAHEC_04432 5.1e-273 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
CINOAHEC_04433 6.9e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CINOAHEC_04434 2.2e-54 yaaQ S protein conserved in bacteria
CINOAHEC_04435 5.9e-71 yaaR S protein conserved in bacteria
CINOAHEC_04436 1.1e-181 holB 2.7.7.7 L DNA polymerase III
CINOAHEC_04437 6.1e-146 yaaT S stage 0 sporulation protein
CINOAHEC_04438 4.8e-31 yabA L Involved in initiation control of chromosome replication
CINOAHEC_04439 7.2e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
CINOAHEC_04440 1.5e-49 yazA L endonuclease containing a URI domain
CINOAHEC_04441 1.2e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CINOAHEC_04442 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
CINOAHEC_04443 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CINOAHEC_04444 3.4e-143 tatD L hydrolase, TatD
CINOAHEC_04445 2e-167 rpfB GH23 T protein conserved in bacteria
CINOAHEC_04446 7.9e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CINOAHEC_04447 1.2e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
CINOAHEC_04448 6.2e-136 yabG S peptidase
CINOAHEC_04449 7.8e-39 veg S protein conserved in bacteria
CINOAHEC_04450 8.3e-27 sspF S DNA topological change
CINOAHEC_04451 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CINOAHEC_04452 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
CINOAHEC_04453 1.1e-62 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
CINOAHEC_04454 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
CINOAHEC_04455 7.3e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CINOAHEC_04456 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CINOAHEC_04457 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CINOAHEC_04458 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
CINOAHEC_04459 2.4e-39 yabK S Peptide ABC transporter permease
CINOAHEC_04460 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CINOAHEC_04461 1.5e-92 spoVT K stage V sporulation protein
CINOAHEC_04462 6.9e-287 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CINOAHEC_04463 6.6e-244 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
CINOAHEC_04464 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
CINOAHEC_04465 1.5e-49 yabP S Sporulation protein YabP
CINOAHEC_04466 4.3e-107 yabQ S spore cortex biosynthesis protein
CINOAHEC_04467 1.1e-44 divIC D Septum formation initiator
CINOAHEC_04468 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
CINOAHEC_04471 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
CINOAHEC_04472 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
CINOAHEC_04473 3.7e-185 KLT serine threonine protein kinase
CINOAHEC_04474 8e-271 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CINOAHEC_04475 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
CINOAHEC_04476 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CINOAHEC_04477 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CINOAHEC_04478 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CINOAHEC_04479 1.3e-151 yacD 5.2.1.8 O peptidyl-prolyl isomerase
CINOAHEC_04480 1.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
CINOAHEC_04481 3.5e-266 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CINOAHEC_04482 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
CINOAHEC_04483 2.3e-167 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
CINOAHEC_04484 2.9e-159 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CINOAHEC_04485 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CINOAHEC_04486 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CINOAHEC_04487 4.1e-30 yazB K transcriptional
CINOAHEC_04488 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CINOAHEC_04489 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)