ORF_ID e_value Gene_name EC_number CAZy COGs Description
HNFAHIGG_00001 7.5e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HNFAHIGG_00002 6.9e-251 yfnA E Amino Acid
HNFAHIGG_00003 0.0 clpE2 O AAA domain (Cdc48 subfamily)
HNFAHIGG_00004 6.5e-157 S Alpha/beta hydrolase of unknown function (DUF915)
HNFAHIGG_00005 2.2e-243 pts13C 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HNFAHIGG_00006 1.1e-39
HNFAHIGG_00007 7e-213 lmrP E Major Facilitator Superfamily
HNFAHIGG_00008 4.5e-174 pbpX2 V Beta-lactamase
HNFAHIGG_00009 4.5e-252 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HNFAHIGG_00010 3.9e-37 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HNFAHIGG_00011 5.5e-236 dltB M MBOAT, membrane-bound O-acyltransferase family
HNFAHIGG_00012 5.3e-289 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HNFAHIGG_00014 3.6e-45
HNFAHIGG_00015 1.7e-199 ywhK S Membrane
HNFAHIGG_00016 3.2e-56
HNFAHIGG_00018 1.8e-41
HNFAHIGG_00019 8.3e-18
HNFAHIGG_00020 3e-84 ykuL S (CBS) domain
HNFAHIGG_00021 0.0 cadA P P-type ATPase
HNFAHIGG_00022 3.5e-200 napA P Sodium/hydrogen exchanger family
HNFAHIGG_00024 2.9e-282 V ABC transporter transmembrane region
HNFAHIGG_00025 1.7e-159 mutR K Helix-turn-helix XRE-family like proteins
HNFAHIGG_00026 8.9e-27
HNFAHIGG_00027 2.8e-32
HNFAHIGG_00028 2.6e-120 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HNFAHIGG_00029 7.7e-158 S Protein of unknown function (DUF979)
HNFAHIGG_00030 2.3e-114 S Protein of unknown function (DUF969)
HNFAHIGG_00031 1.3e-228 G PTS system sugar-specific permease component
HNFAHIGG_00032 1.1e-270 G PTS system Galactitol-specific IIC component
HNFAHIGG_00033 2.6e-94 S Protein of unknown function (DUF1440)
HNFAHIGG_00034 9.1e-105 S CAAX protease self-immunity
HNFAHIGG_00035 9.9e-200 S DUF218 domain
HNFAHIGG_00036 0.0 macB_3 V ABC transporter, ATP-binding protein
HNFAHIGG_00037 8.7e-270 cydA 1.10.3.14 C ubiquinol oxidase
HNFAHIGG_00038 1.7e-182 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HNFAHIGG_00039 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HNFAHIGG_00040 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HNFAHIGG_00041 9.1e-175 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HNFAHIGG_00042 6.4e-168 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
HNFAHIGG_00043 2.7e-194 tcsA S ABC transporter substrate-binding protein PnrA-like
HNFAHIGG_00044 3.1e-172 fpaP 3.4.11.5 I Releases the N-terminal proline from various substrates
HNFAHIGG_00045 4.2e-116 L Transposase DDE domain
HNFAHIGG_00047 8.2e-49 K UTRA
HNFAHIGG_00049 1.1e-67 M glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HNFAHIGG_00050 1.8e-21 G PTS system fructose IIA component
HNFAHIGG_00051 2.3e-44 G PTS system sorbose subfamily IIB component
HNFAHIGG_00052 6e-82 G PTS system sorbose-specific iic component
HNFAHIGG_00053 1.9e-102 G PTS system mannose/fructose/sorbose family IID component
HNFAHIGG_00054 2.4e-123 agaS M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HNFAHIGG_00056 4.2e-181 blaA6 V Beta-lactamase
HNFAHIGG_00057 3.3e-256 pts29C 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HNFAHIGG_00058 2.8e-157 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
HNFAHIGG_00059 2.6e-213 S Bacterial protein of unknown function (DUF871)
HNFAHIGG_00060 1.4e-152 S Putative esterase
HNFAHIGG_00061 2.9e-193 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HNFAHIGG_00062 3e-128 3.5.2.6 V Beta-lactamase enzyme family
HNFAHIGG_00063 1.5e-145 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HNFAHIGG_00064 8.4e-134 S membrane transporter protein
HNFAHIGG_00065 2.5e-18 S PD-(D/E)XK nuclease family transposase
HNFAHIGG_00066 3e-156 yeaE S Aldo/keto reductase family
HNFAHIGG_00067 5.1e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HNFAHIGG_00068 5e-119 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HNFAHIGG_00069 3.7e-125 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HNFAHIGG_00070 5e-237 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HNFAHIGG_00071 3e-232 pbuG S permease
HNFAHIGG_00073 3.5e-105 K helix_turn_helix, mercury resistance
HNFAHIGG_00074 1.4e-229 pbuG S permease
HNFAHIGG_00075 1.7e-45 I bis(5'-adenosyl)-triphosphatase activity
HNFAHIGG_00076 5.2e-227 pbuG S permease
HNFAHIGG_00077 5.3e-66 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HNFAHIGG_00078 4.4e-208 bglF_1 G Psort location CytoplasmicMembrane, score 10.00
HNFAHIGG_00079 2.6e-221 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
HNFAHIGG_00080 8.2e-78 scrR K Periplasmic binding protein domain
HNFAHIGG_00081 9.1e-82
HNFAHIGG_00082 1.3e-83
HNFAHIGG_00083 1.8e-72 atkY K Penicillinase repressor
HNFAHIGG_00084 5.6e-62 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HNFAHIGG_00085 4.1e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HNFAHIGG_00086 0.0 copA 3.6.3.54 P P-type ATPase
HNFAHIGG_00087 2.7e-152 ropB K Helix-turn-helix XRE-family like proteins
HNFAHIGG_00088 0.0 pepO 3.4.24.71 O Peptidase family M13
HNFAHIGG_00089 7.3e-283 E Amino acid permease
HNFAHIGG_00090 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
HNFAHIGG_00091 2.7e-246 ynbB 4.4.1.1 P aluminum resistance
HNFAHIGG_00092 4.3e-74 K Acetyltransferase (GNAT) domain
HNFAHIGG_00093 7.5e-228 EGP Sugar (and other) transporter
HNFAHIGG_00094 2.4e-63 S Iron-sulphur cluster biosynthesis
HNFAHIGG_00095 3.2e-168 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HNFAHIGG_00096 5.7e-128 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HNFAHIGG_00097 3.3e-278 clcA P chloride
HNFAHIGG_00098 3.6e-268 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HNFAHIGG_00099 1.8e-287 V ABC transporter transmembrane region
HNFAHIGG_00100 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HNFAHIGG_00101 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HNFAHIGG_00102 1.8e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HNFAHIGG_00103 3.7e-149 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HNFAHIGG_00104 1.7e-60 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HNFAHIGG_00105 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HNFAHIGG_00106 1.4e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HNFAHIGG_00107 9.4e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HNFAHIGG_00108 3.9e-19 yaaA S S4 domain
HNFAHIGG_00109 4.9e-207 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HNFAHIGG_00110 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HNFAHIGG_00111 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HNFAHIGG_00112 9.4e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
HNFAHIGG_00113 1.7e-82 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HNFAHIGG_00114 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HNFAHIGG_00115 1.1e-156 corA P CorA-like Mg2+ transporter protein
HNFAHIGG_00116 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HNFAHIGG_00117 2.4e-75 rplI J Binds to the 23S rRNA
HNFAHIGG_00118 3.3e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HNFAHIGG_00119 6.5e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HNFAHIGG_00120 3.7e-218 I Protein of unknown function (DUF2974)
HNFAHIGG_00121 0.0
HNFAHIGG_00122 1.7e-117 yhiD S MgtC family
HNFAHIGG_00124 3.1e-110 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HNFAHIGG_00125 7.1e-29 WQ51_00220 K Helix-turn-helix XRE-family like proteins
HNFAHIGG_00126 2.9e-85 S Protein of unknown function (DUF3278)
HNFAHIGG_00127 1.5e-197 S Aldo keto reductase
HNFAHIGG_00129 9.6e-222 S Sterol carrier protein domain
HNFAHIGG_00130 8.8e-116 ywnB S NAD(P)H-binding
HNFAHIGG_00131 9e-71 S Protein of unknown function (DUF975)
HNFAHIGG_00132 1.4e-17 S Protein of unknown function (DUF975)
HNFAHIGG_00133 3.4e-137 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HNFAHIGG_00134 8.1e-154 yitS S EDD domain protein, DegV family
HNFAHIGG_00135 2.2e-19
HNFAHIGG_00136 0.0 tetP J elongation factor G
HNFAHIGG_00137 3.8e-165 P CorA-like Mg2+ transporter protein
HNFAHIGG_00139 2.5e-40 S Transglycosylase associated protein
HNFAHIGG_00140 3.3e-160 xth 3.1.11.2 L exodeoxyribonuclease III
HNFAHIGG_00141 0.0 L Helicase C-terminal domain protein
HNFAHIGG_00142 1.2e-163 S Alpha beta hydrolase
HNFAHIGG_00143 1.8e-40
HNFAHIGG_00144 5.5e-168 K AI-2E family transporter
HNFAHIGG_00145 2.5e-250 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
HNFAHIGG_00146 3.1e-212 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HNFAHIGG_00147 6.8e-104 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
HNFAHIGG_00148 1.8e-192 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HNFAHIGG_00149 0.0 S domain, Protein
HNFAHIGG_00150 0.0 infB UW LPXTG-motif cell wall anchor domain protein
HNFAHIGG_00151 0.0 3.1.31.1 M domain protein
HNFAHIGG_00152 2.4e-206 E amino acid
HNFAHIGG_00153 8e-52 E amino acid
HNFAHIGG_00154 3.7e-168 K LysR substrate binding domain
HNFAHIGG_00155 0.0 1.3.5.4 C FAD binding domain
HNFAHIGG_00156 4.4e-242 brnQ U Component of the transport system for branched-chain amino acids
HNFAHIGG_00157 2.3e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HNFAHIGG_00158 6e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HNFAHIGG_00159 5.5e-88 S Peptidase propeptide and YPEB domain
HNFAHIGG_00160 5.3e-186 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HNFAHIGG_00161 1.7e-249 yhjX_2 P Major Facilitator Superfamily
HNFAHIGG_00162 4.6e-236 yhjX_2 P Major Facilitator Superfamily
HNFAHIGG_00163 2.3e-164 arbZ I Phosphate acyltransferases
HNFAHIGG_00164 3e-181 arbY M Glycosyl transferase family 8
HNFAHIGG_00165 1.9e-183 arbY M Glycosyl transferase family 8
HNFAHIGG_00166 3.2e-155 arbx M Glycosyl transferase family 8
HNFAHIGG_00167 7.8e-151 arbV 2.3.1.51 I Acyl-transferase
HNFAHIGG_00170 1.2e-129 K response regulator
HNFAHIGG_00171 0.0 vicK 2.7.13.3 T Histidine kinase
HNFAHIGG_00172 6.4e-254 yycH S YycH protein
HNFAHIGG_00173 1.4e-142 yycI S YycH protein
HNFAHIGG_00174 3.3e-149 vicX 3.1.26.11 S domain protein
HNFAHIGG_00175 5.4e-183 htrA 3.4.21.107 O serine protease
HNFAHIGG_00176 3.6e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HNFAHIGG_00177 2.8e-109 P Cobalt transport protein
HNFAHIGG_00178 3.9e-251 cbiO1 S ABC transporter, ATP-binding protein
HNFAHIGG_00179 6.2e-94 S ABC-type cobalt transport system, permease component
HNFAHIGG_00180 5.2e-170 K helix_turn_helix, arabinose operon control protein
HNFAHIGG_00181 7.7e-147 htpX O Belongs to the peptidase M48B family
HNFAHIGG_00182 2.2e-91 lemA S LemA family
HNFAHIGG_00183 5.4e-182 ybiR P Citrate transporter
HNFAHIGG_00184 1.3e-69 S Iron-sulphur cluster biosynthesis
HNFAHIGG_00185 1.7e-16
HNFAHIGG_00186 4.1e-153
HNFAHIGG_00188 4.8e-246 ydaM M Glycosyl transferase
HNFAHIGG_00189 1.1e-211 G Glycosyl hydrolases family 8
HNFAHIGG_00190 4.5e-120 yfbR S HD containing hydrolase-like enzyme
HNFAHIGG_00191 1.2e-160 L HNH nucleases
HNFAHIGG_00192 4.7e-137 glnQ E ABC transporter, ATP-binding protein
HNFAHIGG_00193 5.3e-279 glnP P ABC transporter permease
HNFAHIGG_00194 1.2e-104 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HNFAHIGG_00195 1.5e-64 yeaO S Protein of unknown function, DUF488
HNFAHIGG_00196 1.6e-127 terC P Integral membrane protein TerC family
HNFAHIGG_00197 5.9e-94 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
HNFAHIGG_00198 6e-134 cobB K SIR2 family
HNFAHIGG_00199 6.7e-81
HNFAHIGG_00200 6.4e-273 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HNFAHIGG_00201 4.7e-123 yugP S Putative neutral zinc metallopeptidase
HNFAHIGG_00202 6.3e-176 S Alpha/beta hydrolase of unknown function (DUF915)
HNFAHIGG_00203 2.3e-144 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HNFAHIGG_00204 8.4e-163 ypuA S Protein of unknown function (DUF1002)
HNFAHIGG_00205 6.3e-143 2.4.1.293 GT2 M Glycosyltransferase like family 2
HNFAHIGG_00206 9.9e-123 S Alpha/beta hydrolase family
HNFAHIGG_00207 1.6e-61
HNFAHIGG_00208 4.1e-181 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HNFAHIGG_00209 2.5e-209 S CAAX protease self-immunity
HNFAHIGG_00210 3.7e-241 cycA E Amino acid permease
HNFAHIGG_00211 6.4e-114 luxT K Bacterial regulatory proteins, tetR family
HNFAHIGG_00212 7.3e-139
HNFAHIGG_00213 1.2e-283 S Cysteine-rich secretory protein family
HNFAHIGG_00214 1.8e-206 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HNFAHIGG_00215 5.2e-93
HNFAHIGG_00216 3.5e-267 yjcE P Sodium proton antiporter
HNFAHIGG_00217 2e-184 yibE S overlaps another CDS with the same product name
HNFAHIGG_00218 4.9e-118 yibF S overlaps another CDS with the same product name
HNFAHIGG_00219 2.2e-156 I alpha/beta hydrolase fold
HNFAHIGG_00220 0.0 G Belongs to the glycosyl hydrolase 31 family
HNFAHIGG_00221 4.5e-129 XK27_08435 K UTRA
HNFAHIGG_00222 2.1e-216 agaS G SIS domain
HNFAHIGG_00223 1.5e-227 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HNFAHIGG_00224 8.7e-84 2.7.1.191 G PTS system sorbose subfamily IIB component
HNFAHIGG_00225 2.9e-141 XK27_08455 G PTS system sorbose-specific iic component
HNFAHIGG_00226 1.6e-146 manZ_1 G PTS system mannose/fructose/sorbose family IID component
HNFAHIGG_00227 9.3e-68 2.7.1.191 G PTS system fructose IIA component
HNFAHIGG_00228 1.3e-18 S PD-(D/E)XK nuclease family transposase
HNFAHIGG_00229 8.8e-207 S zinc-ribbon domain
HNFAHIGG_00230 7.9e-188
HNFAHIGG_00231 7.4e-88 ntd 2.4.2.6 F Nucleoside
HNFAHIGG_00232 4.9e-99 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HNFAHIGG_00233 1.5e-132 XK27_08440 K UTRA domain
HNFAHIGG_00234 5.7e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
HNFAHIGG_00235 3.8e-87 uspA T universal stress protein
HNFAHIGG_00237 1.2e-80 phnD P Phosphonate ABC transporter
HNFAHIGG_00238 1.2e-36 phnD P Phosphonate ABC transporter
HNFAHIGG_00239 4.3e-141 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HNFAHIGG_00240 2e-130 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HNFAHIGG_00241 1.2e-146 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HNFAHIGG_00242 7.3e-83
HNFAHIGG_00243 1.8e-275 S Calcineurin-like phosphoesterase
HNFAHIGG_00244 0.0 asnB 6.3.5.4 E Asparagine synthase
HNFAHIGG_00245 7.3e-266 yxbA 6.3.1.12 S ATP-grasp enzyme
HNFAHIGG_00246 1.2e-64
HNFAHIGG_00247 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HNFAHIGG_00248 2e-137 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HNFAHIGG_00249 1.9e-104 S Iron-sulfur cluster assembly protein
HNFAHIGG_00250 1e-226 XK27_04775 S PAS domain
HNFAHIGG_00251 0.0 UW LPXTG-motif cell wall anchor domain protein
HNFAHIGG_00252 0.0 UW LPXTG-motif cell wall anchor domain protein
HNFAHIGG_00253 4.2e-228 yttB EGP Major facilitator Superfamily
HNFAHIGG_00254 2.8e-185 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
HNFAHIGG_00255 6.1e-100 D nuclear chromosome segregation
HNFAHIGG_00256 2e-135 rpl K Helix-turn-helix domain, rpiR family
HNFAHIGG_00257 3.3e-164 pfkB 2.7.1.11, 2.7.1.56 H pfkB family carbohydrate kinase
HNFAHIGG_00258 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HNFAHIGG_00260 0.0 pepO 3.4.24.71 O Peptidase family M13
HNFAHIGG_00261 5.4e-199 P ABC transporter
HNFAHIGG_00262 6.2e-224 V ABC-type multidrug transport system, ATPase and permease components
HNFAHIGG_00263 0.0 S Bacterial membrane protein, YfhO
HNFAHIGG_00264 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
HNFAHIGG_00265 0.0 kup P Transport of potassium into the cell
HNFAHIGG_00266 0.0 kup P Transport of potassium into the cell
HNFAHIGG_00267 1.7e-72
HNFAHIGG_00268 2e-109
HNFAHIGG_00269 1.7e-28
HNFAHIGG_00270 1.4e-34 S Protein of unknown function (DUF2922)
HNFAHIGG_00271 3e-265 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HNFAHIGG_00272 8.8e-251 lysA2 M Glycosyl hydrolases family 25
HNFAHIGG_00273 1.1e-144 fruK 2.7.1.11, 2.7.1.56 G pfkB family carbohydrate kinase
HNFAHIGG_00274 0.0 yjbQ P TrkA C-terminal domain protein
HNFAHIGG_00275 1.7e-179 S Oxidoreductase family, NAD-binding Rossmann fold
HNFAHIGG_00276 4e-131
HNFAHIGG_00277 2e-149
HNFAHIGG_00278 1.4e-74 S PAS domain
HNFAHIGG_00279 3.8e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HNFAHIGG_00280 9.7e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HNFAHIGG_00281 3.2e-69 2.4.1.83 GT2 S GtrA-like protein
HNFAHIGG_00282 8e-179 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HNFAHIGG_00283 9.3e-119
HNFAHIGG_00284 1.1e-150 glcU U sugar transport
HNFAHIGG_00285 9e-172 yqhA G Aldose 1-epimerase
HNFAHIGG_00286 5.6e-195 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HNFAHIGG_00287 2.8e-111 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HNFAHIGG_00288 0.0 XK27_08315 M Sulfatase
HNFAHIGG_00289 1.8e-242 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HNFAHIGG_00291 4.9e-262 pepC 3.4.22.40 E aminopeptidase
HNFAHIGG_00292 7.5e-123 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HNFAHIGG_00293 1.9e-255 pepC 3.4.22.40 E aminopeptidase
HNFAHIGG_00294 7.7e-43
HNFAHIGG_00295 8.8e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HNFAHIGG_00296 3.3e-77 hsp O Belongs to the small heat shock protein (HSP20) family
HNFAHIGG_00297 1.3e-292 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HNFAHIGG_00298 1.2e-80
HNFAHIGG_00299 1.4e-248 celD 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HNFAHIGG_00300 4.1e-127 yydK K UTRA
HNFAHIGG_00301 9.6e-47 S Domain of unknown function (DUF3284)
HNFAHIGG_00302 2.6e-304 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HNFAHIGG_00303 6.8e-133 gmuR K UTRA
HNFAHIGG_00304 8.5e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
HNFAHIGG_00305 2e-39
HNFAHIGG_00306 3.4e-52 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HNFAHIGG_00307 4.4e-247 pts23C 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HNFAHIGG_00308 1.1e-280 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HNFAHIGG_00309 6.8e-156 ypbG 2.7.1.2 GK ROK family
HNFAHIGG_00310 4.2e-113
HNFAHIGG_00312 8.6e-113 E Belongs to the SOS response-associated peptidase family
HNFAHIGG_00313 2.6e-194 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HNFAHIGG_00314 4.3e-91 comEB 3.5.4.12 F MafB19-like deaminase
HNFAHIGG_00315 1e-99 S TPM domain
HNFAHIGG_00316 7.9e-92 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HNFAHIGG_00317 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HNFAHIGG_00318 1.8e-147 tatD L hydrolase, TatD family
HNFAHIGG_00319 1.9e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HNFAHIGG_00320 1.2e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HNFAHIGG_00321 7.4e-36 veg S Biofilm formation stimulator VEG
HNFAHIGG_00322 1.7e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HNFAHIGG_00323 1.1e-219 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HNFAHIGG_00324 1.4e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HNFAHIGG_00325 5.8e-177 yvdE K helix_turn _helix lactose operon repressor
HNFAHIGG_00326 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
HNFAHIGG_00327 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HNFAHIGG_00328 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HNFAHIGG_00329 7.1e-113 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HNFAHIGG_00330 3.6e-210 msmX P Belongs to the ABC transporter superfamily
HNFAHIGG_00331 5e-229 malE G Bacterial extracellular solute-binding protein
HNFAHIGG_00332 6.5e-254 malF P Binding-protein-dependent transport system inner membrane component
HNFAHIGG_00333 1.3e-154 malG P ABC transporter permease
HNFAHIGG_00334 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
HNFAHIGG_00335 3.7e-265 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
HNFAHIGG_00336 2.3e-72 S Domain of unknown function (DUF1934)
HNFAHIGG_00337 1.3e-64 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HNFAHIGG_00338 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HNFAHIGG_00339 2.2e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HNFAHIGG_00340 2.5e-234 pbuX F xanthine permease
HNFAHIGG_00341 5.3e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HNFAHIGG_00342 1.1e-133 K DNA-binding helix-turn-helix protein
HNFAHIGG_00343 1.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HNFAHIGG_00345 6e-180 K Helix-turn-helix
HNFAHIGG_00346 4.1e-37
HNFAHIGG_00347 8.1e-67 doc S Fic/DOC family
HNFAHIGG_00348 6.5e-93 K Bacterial regulatory proteins, tetR family
HNFAHIGG_00349 2.6e-111 1.6.5.2 S Flavodoxin-like fold
HNFAHIGG_00350 1.1e-42 yjdF S Protein of unknown function (DUF2992)
HNFAHIGG_00352 7.9e-51
HNFAHIGG_00353 2.3e-29 S Domain of unknown function (DUF4160)
HNFAHIGG_00354 3.1e-58 yjdF S Protein of unknown function (DUF2992)
HNFAHIGG_00355 2.5e-97 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HNFAHIGG_00356 2.6e-94
HNFAHIGG_00357 5.3e-272 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HNFAHIGG_00358 2.3e-278 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HNFAHIGG_00359 2.7e-47 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HNFAHIGG_00360 1.2e-162 yfdV S Membrane transport protein
HNFAHIGG_00361 2.3e-38
HNFAHIGG_00362 9.9e-220 eno2 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HNFAHIGG_00363 4.9e-67 S Putative adhesin
HNFAHIGG_00364 3.9e-78
HNFAHIGG_00365 5.4e-08
HNFAHIGG_00366 5e-281 pipD E Dipeptidase
HNFAHIGG_00367 5.4e-231 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HNFAHIGG_00368 0.0 rafA 3.2.1.22 G alpha-galactosidase
HNFAHIGG_00369 3.4e-186 ABC-SBP S ABC transporter
HNFAHIGG_00370 4.9e-141 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HNFAHIGG_00371 6.9e-136 XK27_08845 S ABC transporter, ATP-binding protein
HNFAHIGG_00372 3.2e-284 ybeC E amino acid
HNFAHIGG_00373 8e-41 rpmE2 J Ribosomal protein L31
HNFAHIGG_00374 2.9e-262 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HNFAHIGG_00375 1.3e-252 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HNFAHIGG_00376 8.5e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HNFAHIGG_00377 1.1e-217 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HNFAHIGG_00378 2.4e-124 S (CBS) domain
HNFAHIGG_00379 8.1e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HNFAHIGG_00380 3.9e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HNFAHIGG_00381 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HNFAHIGG_00382 1.8e-34 yabO J S4 domain protein
HNFAHIGG_00383 2.3e-60 divIC D Septum formation initiator
HNFAHIGG_00384 2.2e-60 yabR J S1 RNA binding domain
HNFAHIGG_00385 8.6e-248 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HNFAHIGG_00386 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HNFAHIGG_00387 0.0 S membrane
HNFAHIGG_00388 4.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HNFAHIGG_00389 3.4e-191 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HNFAHIGG_00390 4.2e-297 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HNFAHIGG_00391 0.0 LV site-specific DNA-methyltransferase (adenine-specific) activity
HNFAHIGG_00392 1.5e-18
HNFAHIGG_00394 1.6e-08
HNFAHIGG_00396 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HNFAHIGG_00397 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HNFAHIGG_00398 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HNFAHIGG_00399 4e-111 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HNFAHIGG_00400 3.5e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HNFAHIGG_00401 1e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HNFAHIGG_00402 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HNFAHIGG_00403 5.8e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HNFAHIGG_00404 2.2e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HNFAHIGG_00405 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
HNFAHIGG_00406 2.2e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HNFAHIGG_00407 4.7e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HNFAHIGG_00408 5e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HNFAHIGG_00409 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HNFAHIGG_00410 3.6e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HNFAHIGG_00411 6.6e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HNFAHIGG_00412 2.2e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HNFAHIGG_00413 7.7e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HNFAHIGG_00414 5.6e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HNFAHIGG_00415 1.4e-34 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HNFAHIGG_00416 1.2e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HNFAHIGG_00417 2.3e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HNFAHIGG_00418 2.7e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HNFAHIGG_00419 3.3e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HNFAHIGG_00420 3.3e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HNFAHIGG_00421 1.9e-76 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HNFAHIGG_00422 1.4e-23 rpmD J Ribosomal protein L30
HNFAHIGG_00423 1.3e-70 rplO J Binds to the 23S rRNA
HNFAHIGG_00424 5.8e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HNFAHIGG_00425 2.7e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HNFAHIGG_00426 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HNFAHIGG_00427 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HNFAHIGG_00428 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HNFAHIGG_00429 2.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HNFAHIGG_00430 1.3e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HNFAHIGG_00431 1.1e-60 rplQ J Ribosomal protein L17
HNFAHIGG_00432 1.5e-155 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HNFAHIGG_00433 1.4e-161 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HNFAHIGG_00434 1.5e-138 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HNFAHIGG_00435 4.2e-152 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HNFAHIGG_00436 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HNFAHIGG_00437 1.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HNFAHIGG_00438 5.8e-73
HNFAHIGG_00439 1e-159 1.6.5.2 GM NmrA-like family
HNFAHIGG_00440 3.8e-110 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HNFAHIGG_00441 9.6e-129 pgm3 G Belongs to the phosphoglycerate mutase family
HNFAHIGG_00442 2.6e-52 K Transcriptional regulator, ArsR family
HNFAHIGG_00443 2.2e-154 czcD P cation diffusion facilitator family transporter
HNFAHIGG_00444 2e-42
HNFAHIGG_00445 1.6e-25
HNFAHIGG_00446 5.2e-127 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HNFAHIGG_00447 2.6e-185 S AAA domain
HNFAHIGG_00448 1.5e-255 pepC 3.4.22.40 E Peptidase C1-like family
HNFAHIGG_00449 6.2e-140 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HNFAHIGG_00450 1.8e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HNFAHIGG_00451 1.1e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HNFAHIGG_00452 5.3e-289 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HNFAHIGG_00453 2.2e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HNFAHIGG_00454 1.7e-78 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HNFAHIGG_00455 1.2e-140 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HNFAHIGG_00456 1.4e-150 lacT K PRD domain
HNFAHIGG_00457 1.9e-56 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
HNFAHIGG_00458 2.2e-291 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
HNFAHIGG_00459 5.9e-290 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
HNFAHIGG_00460 1.6e-97 yvrI K sigma factor activity
HNFAHIGG_00461 1.7e-34
HNFAHIGG_00462 2.9e-271 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HNFAHIGG_00463 7.3e-46 K helix_turn_helix, arabinose operon control protein
HNFAHIGG_00464 7.1e-130 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HNFAHIGG_00465 2.6e-276 bglX 3.2.1.21 GH3 G hydrolase, family 3
HNFAHIGG_00466 2.2e-202 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HNFAHIGG_00467 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HNFAHIGG_00468 5.6e-228 G Major Facilitator Superfamily
HNFAHIGG_00469 9.3e-189 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HNFAHIGG_00470 1.8e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HNFAHIGG_00471 9.1e-12 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HNFAHIGG_00472 2e-100 nusG K Participates in transcription elongation, termination and antitermination
HNFAHIGG_00473 5.3e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HNFAHIGG_00474 1.6e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HNFAHIGG_00475 4.6e-109 glnP P ABC transporter permease
HNFAHIGG_00476 2e-115 glnQ 3.6.3.21 E ABC transporter
HNFAHIGG_00477 1.4e-147 aatB ET ABC transporter substrate-binding protein
HNFAHIGG_00478 3.1e-96 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HNFAHIGG_00479 9.4e-51 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HNFAHIGG_00480 8.2e-149 kcsA P Ion transport protein
HNFAHIGG_00481 1.6e-32
HNFAHIGG_00482 3.3e-112 rsmC 2.1.1.172 J Methyltransferase
HNFAHIGG_00483 1.9e-23
HNFAHIGG_00484 8.4e-81 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HNFAHIGG_00485 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HNFAHIGG_00486 5.9e-52 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HNFAHIGG_00487 6.2e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HNFAHIGG_00488 5.3e-26 S Protein of unknown function (DUF2508)
HNFAHIGG_00489 3.4e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HNFAHIGG_00490 4.5e-52 yaaQ S Cyclic-di-AMP receptor
HNFAHIGG_00491 2.4e-153 holB 2.7.7.7 L DNA polymerase III
HNFAHIGG_00492 4.9e-57 yabA L Involved in initiation control of chromosome replication
HNFAHIGG_00493 6.7e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HNFAHIGG_00494 5.6e-127 fat 3.1.2.21 I Acyl-ACP thioesterase
HNFAHIGG_00495 1.5e-86 folT S ECF transporter, substrate-specific component
HNFAHIGG_00496 4.9e-131 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HNFAHIGG_00497 7.1e-98 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HNFAHIGG_00498 6.2e-196 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HNFAHIGG_00499 1e-14 D nuclear chromosome segregation
HNFAHIGG_00500 1.6e-51
HNFAHIGG_00502 1e-165 S AAA domain, putative AbiEii toxin, Type IV TA system
HNFAHIGG_00503 3.3e-253 clcA P chloride
HNFAHIGG_00504 4.5e-48
HNFAHIGG_00505 4.1e-189 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HNFAHIGG_00506 1.2e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HNFAHIGG_00507 1.8e-245 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HNFAHIGG_00508 1.1e-75 apfA 2.7.7.72, 3.6.1.61 F NUDIX domain
HNFAHIGG_00509 1.2e-48 L bacterial-type proximal promoter sequence-specific DNA binding
HNFAHIGG_00510 1.7e-53 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HNFAHIGG_00511 1.7e-229 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HNFAHIGG_00512 0.0 uup S ABC transporter, ATP-binding protein
HNFAHIGG_00513 8.7e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HNFAHIGG_00514 1.6e-94 yvdD 3.2.2.10 S Belongs to the LOG family
HNFAHIGG_00515 2.5e-24 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HNFAHIGG_00516 8.1e-128 K Psort location Cytoplasmic, score 8.87
HNFAHIGG_00517 1.1e-21 S Domain of unknown function (DUF3284)
HNFAHIGG_00518 1.6e-23 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HNFAHIGG_00519 8.8e-21 pts15B 2.7.1.196, 2.7.1.205 G system, Lactose Cellobiose specific IIB subunit
HNFAHIGG_00520 3e-128 pts15C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HNFAHIGG_00521 1.5e-240 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HNFAHIGG_00522 7.4e-77 XK27_02470 K LytTr DNA-binding domain
HNFAHIGG_00523 1.3e-118 liaI S membrane
HNFAHIGG_00525 8.8e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HNFAHIGG_00526 3.5e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HNFAHIGG_00527 1e-222 nisT V ABC transporter
HNFAHIGG_00528 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HNFAHIGG_00529 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HNFAHIGG_00530 1.6e-100 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HNFAHIGG_00531 1.4e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HNFAHIGG_00532 4.5e-31 yajC U Preprotein translocase
HNFAHIGG_00533 1.1e-283 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HNFAHIGG_00534 6.9e-209 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HNFAHIGG_00535 6.6e-184 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HNFAHIGG_00536 1.5e-229 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HNFAHIGG_00537 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HNFAHIGG_00538 2.6e-42 yrzL S Belongs to the UPF0297 family
HNFAHIGG_00539 1.4e-72 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HNFAHIGG_00540 1.8e-50 yrzB S Belongs to the UPF0473 family
HNFAHIGG_00541 3.4e-89 cvpA S Colicin V production protein
HNFAHIGG_00542 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HNFAHIGG_00543 1.1e-52 trxA O Belongs to the thioredoxin family
HNFAHIGG_00544 2.4e-68 yslB S Protein of unknown function (DUF2507)
HNFAHIGG_00545 5.5e-144 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HNFAHIGG_00546 1.9e-115 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HNFAHIGG_00547 2.9e-218 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HNFAHIGG_00548 3.7e-157 ykuT M mechanosensitive ion channel
HNFAHIGG_00550 4e-51
HNFAHIGG_00551 5.9e-213 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HNFAHIGG_00552 1.6e-177 ccpA K catabolite control protein A
HNFAHIGG_00553 1.4e-295 V ABC transporter transmembrane region
HNFAHIGG_00554 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M Penicillin binding protein transpeptidase domain
HNFAHIGG_00555 2e-274 pepV 3.5.1.18 E dipeptidase PepV
HNFAHIGG_00556 1.7e-265 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HNFAHIGG_00557 2e-55
HNFAHIGG_00558 1.5e-266 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HNFAHIGG_00559 3.5e-97 yutD S Protein of unknown function (DUF1027)
HNFAHIGG_00560 3.6e-148 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HNFAHIGG_00561 7.2e-104 S Protein of unknown function (DUF1461)
HNFAHIGG_00562 2.7e-117 dedA S SNARE-like domain protein
HNFAHIGG_00563 9.1e-178 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
HNFAHIGG_00564 6e-61 yugI 5.3.1.9 J general stress protein
HNFAHIGG_00567 7.3e-94 sip L Belongs to the 'phage' integrase family
HNFAHIGG_00568 6.2e-39 3.4.21.88 K Peptidase S24-like
HNFAHIGG_00569 8.4e-11 K Helix-turn-helix XRE-family like proteins
HNFAHIGG_00570 1.2e-07 S Helix-turn-helix domain
HNFAHIGG_00573 6.6e-20 L Psort location Cytoplasmic, score
HNFAHIGG_00578 5.4e-07 K Transcriptional
HNFAHIGG_00582 4.3e-72 endA F DNA RNA non-specific endonuclease
HNFAHIGG_00589 4.8e-16 D nuclear chromosome segregation
HNFAHIGG_00591 8.9e-31 3.4.22.70 M Sortase family
HNFAHIGG_00592 2.5e-85 M Gram-positive pilin backbone subunit 2, Cna-B-like domain
HNFAHIGG_00593 1.1e-41 3.4.22.70 M Sortase family
HNFAHIGG_00601 1.1e-152 U TraM recognition site of TraD and TraG
HNFAHIGG_00602 2.7e-32 I mechanosensitive ion channel activity
HNFAHIGG_00604 9.9e-16
HNFAHIGG_00605 1.1e-156 trsE S COG0433 Predicted ATPase
HNFAHIGG_00606 2.7e-36 trwN GH23 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HNFAHIGG_00609 2.5e-12 CO Thioredoxin
HNFAHIGG_00611 2e-06
HNFAHIGG_00614 5.6e-50 S COG0790 FOG TPR repeat, SEL1 subfamily
HNFAHIGG_00616 7.7e-42 L Protein of unknown function (DUF3991)
HNFAHIGG_00619 3.7e-89 2.1.1.37 L C-5 cytosine-specific DNA methylase
HNFAHIGG_00621 3.6e-15 L Psort location Cytoplasmic, score
HNFAHIGG_00622 1.1e-20 L Psort location Cytoplasmic, score
HNFAHIGG_00623 4.3e-51 E Pfam:DUF955
HNFAHIGG_00627 2e-13
HNFAHIGG_00628 1.4e-26 S endonuclease activity
HNFAHIGG_00629 2.6e-10 S RelB antitoxin
HNFAHIGG_00631 7.8e-90 D CobQ CobB MinD ParA nucleotide binding domain protein
HNFAHIGG_00633 5.4e-167 topA2 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HNFAHIGG_00634 5.4e-17 XK27_07075 S CAAX protease self-immunity
HNFAHIGG_00635 3.3e-35 gepA S Protein of unknown function (DUF4065)
HNFAHIGG_00637 5.8e-28 N PFAM Uncharacterised protein family UPF0150
HNFAHIGG_00638 3.2e-13 S Phage derived protein Gp49-like (DUF891)
HNFAHIGG_00642 9.6e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HNFAHIGG_00643 3.2e-259 qacA EGP Major facilitator Superfamily
HNFAHIGG_00644 2.5e-118 3.6.1.27 I Acid phosphatase homologues
HNFAHIGG_00645 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HNFAHIGG_00646 7.1e-303 ytgP S Polysaccharide biosynthesis protein
HNFAHIGG_00647 2.6e-216 I Protein of unknown function (DUF2974)
HNFAHIGG_00648 8e-121
HNFAHIGG_00649 1.5e-147 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HNFAHIGG_00650 8.3e-125 M ErfK YbiS YcfS YnhG
HNFAHIGG_00651 1.8e-170 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HNFAHIGG_00652 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HNFAHIGG_00653 6.5e-173 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HNFAHIGG_00654 3.8e-48
HNFAHIGG_00655 9.3e-74 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
HNFAHIGG_00656 1.1e-53 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HNFAHIGG_00658 3.2e-95 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HNFAHIGG_00659 1.3e-127 yfeJ 6.3.5.2 F Glutamine amidotransferase class-I
HNFAHIGG_00660 2.7e-109 ylbE GM NAD(P)H-binding
HNFAHIGG_00661 1.8e-83 yebR 1.8.4.14 T GAF domain-containing protein
HNFAHIGG_00662 7.2e-194 S Bacteriocin helveticin-J
HNFAHIGG_00663 9.6e-106 tag 3.2.2.20 L glycosylase
HNFAHIGG_00664 3.6e-163 mleP3 S Membrane transport protein
HNFAHIGG_00665 5.3e-122 S CAAX amino terminal protease
HNFAHIGG_00666 4e-144 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HNFAHIGG_00667 4.9e-255 emrY EGP Major facilitator Superfamily
HNFAHIGG_00668 3.2e-259 emrY EGP Major facilitator Superfamily
HNFAHIGG_00669 5.4e-84 rhaS6 K helix_turn_helix, arabinose operon control protein
HNFAHIGG_00670 1.2e-134 G Major Facilitator Superfamily
HNFAHIGG_00671 1.5e-88 S phospholipase Carboxylesterase
HNFAHIGG_00672 2.2e-93 yxdD K Bacterial regulatory proteins, tetR family
HNFAHIGG_00673 0.0 4.2.1.53 S Myosin-crossreactive antigen
HNFAHIGG_00674 1.5e-76 2.3.1.128 K acetyltransferase
HNFAHIGG_00675 2.4e-144 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HNFAHIGG_00676 3.2e-103 yagU S Protein of unknown function (DUF1440)
HNFAHIGG_00677 4.7e-151 S hydrolase
HNFAHIGG_00678 9.6e-131 K Transcriptional regulator
HNFAHIGG_00679 1.1e-240 pyrP F Permease
HNFAHIGG_00680 1.3e-137 lacR K DeoR C terminal sensor domain
HNFAHIGG_00681 9.4e-74 lacA 5.3.1.26 G Ribose/Galactose Isomerase
HNFAHIGG_00682 1.9e-106 rpiB 2.1.1.222, 2.1.1.64, 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
HNFAHIGG_00683 6.2e-128 S Domain of unknown function (DUF4867)
HNFAHIGG_00684 7.2e-86 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HNFAHIGG_00685 6.3e-51 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
HNFAHIGG_00686 1.4e-267 gatC G PTS system sugar-specific permease component
HNFAHIGG_00687 1.3e-38
HNFAHIGG_00688 2.1e-149 lacT K CAT RNA binding domain
HNFAHIGG_00689 8.7e-57 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
HNFAHIGG_00690 0.0 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
HNFAHIGG_00691 1.4e-291 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
HNFAHIGG_00692 1e-201 S PFAM Archaeal ATPase
HNFAHIGG_00693 1.8e-164 K LysR family
HNFAHIGG_00694 0.0 1.3.5.4 C FMN_bind
HNFAHIGG_00695 3.7e-260 P Sodium:sulfate symporter transmembrane region
HNFAHIGG_00696 4.4e-33 glsA 3.5.1.2 E Belongs to the glutaminase family
HNFAHIGG_00697 6.7e-113 glsA 3.5.1.2 E Belongs to the glutaminase family
HNFAHIGG_00698 1.2e-100 scrR K helix_turn _helix lactose operon repressor
HNFAHIGG_00699 3.8e-239 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
HNFAHIGG_00700 3.2e-202 malL 3.2.1.10 GH13 G Alpha-amylase domain
HNFAHIGG_00701 5.7e-159 rafA 3.2.1.22 G alpha-galactosidase
HNFAHIGG_00702 1.1e-110 3.6.1.27 I Acid phosphatase homologues
HNFAHIGG_00703 6.3e-216 mdtG EGP Major facilitator Superfamily
HNFAHIGG_00704 1.2e-26
HNFAHIGG_00705 9.8e-71 K helix_turn_helix multiple antibiotic resistance protein
HNFAHIGG_00706 9.2e-80
HNFAHIGG_00707 3.6e-207 pepA E M42 glutamyl aminopeptidase
HNFAHIGG_00709 5.9e-88 2.7.1.191 G PTS system sorbose subfamily IIB component
HNFAHIGG_00710 1.2e-103 G PTS system sorbose-specific iic component
HNFAHIGG_00711 3.4e-152 G PTS system mannose/fructose/sorbose family IID component
HNFAHIGG_00712 1.2e-71 2.7.1.191 G PTS system fructose IIA component
HNFAHIGG_00713 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HNFAHIGG_00714 8.2e-182 lacI3 K helix_turn _helix lactose operon repressor
HNFAHIGG_00715 0.0 3.2.1.177 GH31 G Glycosyl hydrolases family 31
HNFAHIGG_00716 1.6e-266 dtpT U amino acid peptide transporter
HNFAHIGG_00717 1.7e-208 naiP EGP Major facilitator Superfamily
HNFAHIGG_00718 2.9e-151 S Alpha beta hydrolase
HNFAHIGG_00719 2.3e-75 K Transcriptional regulator, MarR family
HNFAHIGG_00720 1e-299 XK27_09600 V ABC transporter, ATP-binding protein
HNFAHIGG_00721 0.0 V ABC transporter transmembrane region
HNFAHIGG_00722 1.4e-147 glnH ET ABC transporter
HNFAHIGG_00723 8e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HNFAHIGG_00724 9.1e-150 glnH ET ABC transporter
HNFAHIGG_00725 3.2e-110 gluC P ABC transporter permease
HNFAHIGG_00726 2e-107 glnP P ABC transporter permease
HNFAHIGG_00727 1.3e-156 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HNFAHIGG_00728 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
HNFAHIGG_00729 1.2e-129 treR K UTRA
HNFAHIGG_00730 3.6e-106 treB 2.7.1.211 G phosphotransferase system
HNFAHIGG_00731 1.3e-216 treB 2.7.1.211 G phosphotransferase system
HNFAHIGG_00732 3.2e-83 S Putative adhesin
HNFAHIGG_00733 5.2e-113 udk 2.7.1.48 F Cytidine monophosphokinase
HNFAHIGG_00734 1.1e-205 EGP Major facilitator superfamily
HNFAHIGG_00736 2e-52 S Enterocin A Immunity
HNFAHIGG_00737 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
HNFAHIGG_00738 2.4e-161 rssA S Phospholipase, patatin family
HNFAHIGG_00739 9e-257 glnPH2 P ABC transporter permease
HNFAHIGG_00740 1.7e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HNFAHIGG_00741 1.1e-95 K Acetyltransferase (GNAT) domain
HNFAHIGG_00742 1e-159 pstS P Phosphate
HNFAHIGG_00743 2.1e-161 pstC P probably responsible for the translocation of the substrate across the membrane
HNFAHIGG_00744 8.3e-157 pstA P Phosphate transport system permease protein PstA
HNFAHIGG_00745 3.1e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HNFAHIGG_00746 1.7e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HNFAHIGG_00747 2.6e-118 phoU P Plays a role in the regulation of phosphate uptake
HNFAHIGG_00748 1.9e-281 S C4-dicarboxylate anaerobic carrier
HNFAHIGG_00749 5.8e-85 dps P Belongs to the Dps family
HNFAHIGG_00751 9.4e-164 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HNFAHIGG_00752 9.4e-124 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HNFAHIGG_00753 4.5e-174 rihB 3.2.2.1 F Nucleoside
HNFAHIGG_00754 4e-133 gntR K UbiC transcription regulator-associated domain protein
HNFAHIGG_00755 2e-52 S Enterocin A Immunity
HNFAHIGG_00756 8.9e-139 glcR K DeoR C terminal sensor domain
HNFAHIGG_00757 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HNFAHIGG_00758 1.7e-119 C nitroreductase
HNFAHIGG_00759 1.1e-132
HNFAHIGG_00760 3.6e-252 yhdP S Transporter associated domain
HNFAHIGG_00761 2.8e-102 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HNFAHIGG_00762 2.9e-235 potE E amino acid
HNFAHIGG_00763 2.6e-137 M Glycosyl hydrolases family 25
HNFAHIGG_00764 4.1e-207 yfmL 3.6.4.13 L DEAD DEAH box helicase
HNFAHIGG_00765 2.1e-249 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HNFAHIGG_00768 1.2e-216 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HNFAHIGG_00769 8e-88 gtcA S Teichoic acid glycosylation protein
HNFAHIGG_00770 8.5e-78 fld C Flavodoxin
HNFAHIGG_00771 6.7e-161 map 3.4.11.18 E Methionine Aminopeptidase
HNFAHIGG_00772 7.7e-166 yihY S Belongs to the UPF0761 family
HNFAHIGG_00773 2.3e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HNFAHIGG_00774 4.6e-146 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HNFAHIGG_00775 4.4e-180 E ABC transporter, ATP-binding protein
HNFAHIGG_00776 6e-288 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HNFAHIGG_00777 1.4e-66 O OsmC-like protein
HNFAHIGG_00778 9.5e-39 ltrA S Bacterial low temperature requirement A protein (LtrA)
HNFAHIGG_00779 1e-113 2.7.6.5 T Region found in RelA / SpoT proteins
HNFAHIGG_00780 2.4e-116 K response regulator
HNFAHIGG_00781 5e-232 sptS 2.7.13.3 T Histidine kinase
HNFAHIGG_00782 1.1e-28 rnhA 3.1.26.4 L Caulimovirus viroplasmin
HNFAHIGG_00783 2.5e-164 U Type IV secretory system Conjugative DNA transfer
HNFAHIGG_00784 3.8e-07
HNFAHIGG_00786 5.6e-42 K Helix-turn-helix XRE-family like proteins
HNFAHIGG_00787 4.2e-45
HNFAHIGG_00788 5.4e-44
HNFAHIGG_00790 6.1e-164 S Bacterial membrane protein, YfhO
HNFAHIGG_00791 1.1e-146 S Bacterial membrane protein, YfhO
HNFAHIGG_00793 4.6e-101 K Helix-turn-helix XRE-family like proteins
HNFAHIGG_00794 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HNFAHIGG_00795 2.4e-56
HNFAHIGG_00796 1.4e-57
HNFAHIGG_00797 0.0 pepN 3.4.11.2 E aminopeptidase
HNFAHIGG_00798 1.2e-140 S haloacid dehalogenase-like hydrolase
HNFAHIGG_00799 1.8e-122 S CAAX protease self-immunity
HNFAHIGG_00801 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HNFAHIGG_00802 6.6e-72
HNFAHIGG_00803 4e-107 fic D Fic/DOC family
HNFAHIGG_00804 1.8e-225 I transferase activity, transferring acyl groups other than amino-acyl groups
HNFAHIGG_00805 3.5e-128 pnb C nitroreductase
HNFAHIGG_00806 2.5e-98 S Domain of unknown function (DUF4811)
HNFAHIGG_00807 1.8e-265 lmrB EGP Major facilitator Superfamily
HNFAHIGG_00808 1.2e-76 K MerR HTH family regulatory protein
HNFAHIGG_00809 0.0 oppA E ABC transporter substrate-binding protein
HNFAHIGG_00810 4.6e-61 pdxH S Pyridoxamine 5'-phosphate oxidase
HNFAHIGG_00811 1.4e-256 pepC 3.4.22.40 E Peptidase C1-like family
HNFAHIGG_00812 2.1e-168 2.7.1.2 GK ROK family
HNFAHIGG_00813 2.4e-164 rhaS6 K helix_turn_helix, arabinose operon control protein
HNFAHIGG_00814 9.5e-177 I Carboxylesterase family
HNFAHIGG_00815 3.3e-161 yhjX P Major Facilitator Superfamily
HNFAHIGG_00816 7.3e-306 S Predicted membrane protein (DUF2207)
HNFAHIGG_00817 7.6e-55 K Acetyltransferase (GNAT) domain
HNFAHIGG_00818 8.9e-89
HNFAHIGG_00819 6.3e-151 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HNFAHIGG_00820 1.2e-92 S ECF-type riboflavin transporter, S component
HNFAHIGG_00821 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HNFAHIGG_00822 1.2e-12
HNFAHIGG_00823 2.9e-152 S Uncharacterized protein conserved in bacteria (DUF2325)
HNFAHIGG_00824 4.5e-61 S Uncharacterized protein conserved in bacteria (DUF2325)
HNFAHIGG_00825 2.7e-149 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HNFAHIGG_00826 8.1e-63 arsC 1.20.4.1 P Belongs to the ArsC family
HNFAHIGG_00827 2e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HNFAHIGG_00828 2.8e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HNFAHIGG_00829 9.5e-195 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HNFAHIGG_00830 8.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HNFAHIGG_00831 2.2e-73 yqhY S Asp23 family, cell envelope-related function
HNFAHIGG_00832 8e-67 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HNFAHIGG_00833 2.1e-154 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HNFAHIGG_00834 1.5e-253 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HNFAHIGG_00835 3.8e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HNFAHIGG_00836 7.8e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HNFAHIGG_00837 3.7e-156 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HNFAHIGG_00838 3.8e-264 recN L May be involved in recombinational repair of damaged DNA
HNFAHIGG_00839 4.6e-48
HNFAHIGG_00840 4.7e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HNFAHIGG_00841 1.7e-31 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HNFAHIGG_00842 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HNFAHIGG_00843 7.1e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HNFAHIGG_00844 1.2e-241 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HNFAHIGG_00845 4.5e-140 stp 3.1.3.16 T phosphatase
HNFAHIGG_00846 0.0 KLT serine threonine protein kinase
HNFAHIGG_00847 5.9e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HNFAHIGG_00848 3.1e-121 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HNFAHIGG_00849 1.1e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
HNFAHIGG_00850 1.6e-25 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HNFAHIGG_00851 1.4e-57 asp S Asp23 family, cell envelope-related function
HNFAHIGG_00852 9.6e-308 yloV S DAK2 domain fusion protein YloV
HNFAHIGG_00853 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HNFAHIGG_00854 5.8e-183 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HNFAHIGG_00855 2.6e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNFAHIGG_00856 1.1e-192 oppD P Belongs to the ABC transporter superfamily
HNFAHIGG_00857 4.4e-180 oppF P Belongs to the ABC transporter superfamily
HNFAHIGG_00858 7.5e-180 oppB P ABC transporter permease
HNFAHIGG_00859 2.1e-163 oppC P Binding-protein-dependent transport system inner membrane component
HNFAHIGG_00860 0.0 oppA E ABC transporter substrate-binding protein
HNFAHIGG_00861 0.0 oppA E ABC transporter substrate-binding protein
HNFAHIGG_00862 6e-123 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HNFAHIGG_00863 0.0 smc D Required for chromosome condensation and partitioning
HNFAHIGG_00864 5.1e-166 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HNFAHIGG_00865 4.7e-287 pipD E Dipeptidase
HNFAHIGG_00866 4.9e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HNFAHIGG_00867 1.9e-227 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HNFAHIGG_00868 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HNFAHIGG_00869 7.4e-97 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HNFAHIGG_00870 2.2e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HNFAHIGG_00871 5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HNFAHIGG_00872 4.6e-117 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HNFAHIGG_00873 6.5e-75 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HNFAHIGG_00874 1.5e-115 ung2 3.2.2.27 L Uracil-DNA glycosylase
HNFAHIGG_00875 7.9e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HNFAHIGG_00876 1.2e-33 ynzC S UPF0291 protein
HNFAHIGG_00877 1.9e-30 yneF S Uncharacterised protein family (UPF0154)
HNFAHIGG_00878 0.0 mdlA V ABC transporter
HNFAHIGG_00879 5.1e-299 mdlB V ABC transporter
HNFAHIGG_00880 3.5e-211 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HNFAHIGG_00881 9.8e-117 plsC 2.3.1.51 I Acyltransferase
HNFAHIGG_00882 1.1e-194 yabB 2.1.1.223 L Methyltransferase small domain
HNFAHIGG_00883 2.8e-140 rpsB J Belongs to the universal ribosomal protein uS2 family
HNFAHIGG_00884 3.8e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HNFAHIGG_00885 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HNFAHIGG_00886 3.4e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HNFAHIGG_00887 3.9e-133 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HNFAHIGG_00888 3.4e-138 cdsA 2.7.7.41 S Belongs to the CDS family
HNFAHIGG_00889 1.2e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HNFAHIGG_00890 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HNFAHIGG_00891 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HNFAHIGG_00892 4.7e-82 rimP J Required for maturation of 30S ribosomal subunits
HNFAHIGG_00893 1.1e-217 nusA K Participates in both transcription termination and antitermination
HNFAHIGG_00894 3.4e-46 ylxR K Protein of unknown function (DUF448)
HNFAHIGG_00895 1.8e-45 rplGA J ribosomal protein
HNFAHIGG_00896 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HNFAHIGG_00897 7.9e-61 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HNFAHIGG_00898 2.2e-165 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HNFAHIGG_00899 5.4e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HNFAHIGG_00900 1.6e-282 lsa S ABC transporter
HNFAHIGG_00901 1.5e-120 S GyrI-like small molecule binding domain
HNFAHIGG_00902 2.9e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HNFAHIGG_00903 8.5e-78 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HNFAHIGG_00904 0.0 dnaK O Heat shock 70 kDa protein
HNFAHIGG_00905 4.5e-171 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HNFAHIGG_00906 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HNFAHIGG_00907 7.9e-123 srtA 3.4.22.70 M sortase family
HNFAHIGG_00908 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HNFAHIGG_00909 1.3e-96 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HNFAHIGG_00910 3.9e-276 yjeM E Amino Acid
HNFAHIGG_00911 2.1e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HNFAHIGG_00912 1.4e-189 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HNFAHIGG_00913 1.1e-94 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HNFAHIGG_00914 3e-251 G Major Facilitator
HNFAHIGG_00915 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
HNFAHIGG_00916 4.2e-158 lysR5 K LysR substrate binding domain
HNFAHIGG_00918 2.2e-102 3.6.1.27 I Acid phosphatase homologues
HNFAHIGG_00919 1.6e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HNFAHIGG_00920 1.1e-17 S Sugar efflux transporter for intercellular exchange
HNFAHIGG_00921 3.4e-310 ybiT S ABC transporter, ATP-binding protein
HNFAHIGG_00922 2.7e-41 K Helix-turn-helix domain
HNFAHIGG_00923 1.2e-144 F DNA/RNA non-specific endonuclease
HNFAHIGG_00924 4.2e-58 L nuclease
HNFAHIGG_00925 2e-155 metQ1 P Belongs to the nlpA lipoprotein family
HNFAHIGG_00926 6.3e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HNFAHIGG_00927 2.8e-67 metI P ABC transporter permease
HNFAHIGG_00928 5.5e-264 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HNFAHIGG_00929 8.9e-259 frdC 1.3.5.4 C FAD binding domain
HNFAHIGG_00930 8.9e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HNFAHIGG_00931 2.2e-257 yjjP S Putative threonine/serine exporter
HNFAHIGG_00932 2.5e-189 ansA 3.5.1.1 EJ L-asparaginase, type I
HNFAHIGG_00933 0.0 aha1 P E1-E2 ATPase
HNFAHIGG_00934 0.0 S Bacterial membrane protein, YfhO
HNFAHIGG_00935 8.7e-87 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HNFAHIGG_00936 6.1e-174 prmA J Ribosomal protein L11 methyltransferase
HNFAHIGG_00937 2.4e-65
HNFAHIGG_00938 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HNFAHIGG_00939 2.8e-73 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HNFAHIGG_00940 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
HNFAHIGG_00941 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HNFAHIGG_00942 3.1e-73
HNFAHIGG_00943 1.5e-82 mutT 3.6.1.55 F NUDIX domain
HNFAHIGG_00944 1.7e-34
HNFAHIGG_00945 1.2e-67
HNFAHIGG_00946 2.3e-63 S Domain of unknown function DUF1828
HNFAHIGG_00947 2e-85 S Rib/alpha-like repeat
HNFAHIGG_00948 9.4e-245 yagE E amino acid
HNFAHIGG_00949 1.8e-113 GM NmrA-like family
HNFAHIGG_00950 1.9e-96 dedA 3.1.3.1 S SNARE associated Golgi protein
HNFAHIGG_00951 2.7e-174 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
HNFAHIGG_00952 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HNFAHIGG_00953 3.9e-240 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HNFAHIGG_00954 0.0 oatA I Acyltransferase
HNFAHIGG_00955 3e-178 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HNFAHIGG_00956 2.7e-143 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HNFAHIGG_00957 2.2e-46 yrvD S Lipopolysaccharide assembly protein A domain
HNFAHIGG_00958 1e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HNFAHIGG_00959 3.4e-307 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HNFAHIGG_00960 2.1e-28 S Protein of unknown function (DUF2929)
HNFAHIGG_00961 0.0 dnaE 2.7.7.7 L DNA polymerase
HNFAHIGG_00963 2.7e-182 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HNFAHIGG_00964 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HNFAHIGG_00965 5.7e-166 cvfB S S1 domain
HNFAHIGG_00966 9.6e-169 xerD D recombinase XerD
HNFAHIGG_00967 4.5e-61 ribT K acetyltransferase
HNFAHIGG_00968 3.7e-134 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HNFAHIGG_00969 1.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HNFAHIGG_00970 4.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HNFAHIGG_00971 2.1e-49 M Lysin motif
HNFAHIGG_00972 7.6e-98 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HNFAHIGG_00973 4e-116 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HNFAHIGG_00974 2.3e-218 rpsA 1.17.7.4 J Ribosomal protein S1
HNFAHIGG_00975 9.4e-242 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HNFAHIGG_00976 2e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HNFAHIGG_00977 6.7e-229 S Tetratricopeptide repeat protein
HNFAHIGG_00978 0.0 KL domain protein
HNFAHIGG_00979 5.2e-127
HNFAHIGG_00980 1.2e-275 hsdM 2.1.1.72 V type I restriction-modification system
HNFAHIGG_00981 1.8e-50 3.1.21.3 V Type I restriction modification DNA specificity domain
HNFAHIGG_00982 2.7e-177 L Belongs to the 'phage' integrase family
HNFAHIGG_00983 1.8e-50 3.1.21.3 V Type I restriction modification DNA specificity domain
HNFAHIGG_00984 2.7e-177 L Belongs to the 'phage' integrase family
HNFAHIGG_00985 3.5e-128 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
HNFAHIGG_00986 0.0 hsdR 3.1.21.3 V EcoEI R protein C-terminal
HNFAHIGG_00987 0.0 S Protein of unknown function DUF262
HNFAHIGG_00988 0.0 1.3.5.4 C FMN_bind
HNFAHIGG_00989 9.3e-13
HNFAHIGG_00990 1.1e-75
HNFAHIGG_00991 2.7e-160 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HNFAHIGG_00992 3.6e-224 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HNFAHIGG_00993 7.6e-115 hlyIII S protein, hemolysin III
HNFAHIGG_00994 1.9e-150 DegV S Uncharacterised protein, DegV family COG1307
HNFAHIGG_00995 9.2e-36 yozE S Belongs to the UPF0346 family
HNFAHIGG_00996 1.1e-264 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HNFAHIGG_00997 3.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HNFAHIGG_00998 9.8e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HNFAHIGG_00999 3.4e-152 dprA LU DNA protecting protein DprA
HNFAHIGG_01000 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HNFAHIGG_01001 3.3e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HNFAHIGG_01002 2e-169 xerC D Phage integrase, N-terminal SAM-like domain
HNFAHIGG_01003 9.7e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HNFAHIGG_01004 8.2e-252 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HNFAHIGG_01005 1.3e-178 lacX 5.1.3.3 G Aldose 1-epimerase
HNFAHIGG_01006 8.5e-97 K LysR substrate binding domain
HNFAHIGG_01007 5.9e-100 S LexA-binding, inner membrane-associated putative hydrolase
HNFAHIGG_01009 5.6e-64
HNFAHIGG_01010 3.4e-178 MA20_14895 S Conserved hypothetical protein 698
HNFAHIGG_01011 5.9e-70 K Transcriptional regulator
HNFAHIGG_01012 2.6e-49
HNFAHIGG_01013 1.1e-42
HNFAHIGG_01014 9.7e-40 K peptidyl-tyrosine sulfation
HNFAHIGG_01015 1.7e-119 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HNFAHIGG_01016 2.4e-110 ybbL S ABC transporter, ATP-binding protein
HNFAHIGG_01017 1e-131 ybbM S Uncharacterised protein family (UPF0014)
HNFAHIGG_01018 4.3e-97 K Acetyltransferase (GNAT) domain
HNFAHIGG_01019 3e-309 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HNFAHIGG_01020 7e-114 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
HNFAHIGG_01021 2.3e-106 S Protein of unknown function (DUF1211)
HNFAHIGG_01022 0.0 S domain, Protein
HNFAHIGG_01024 2.6e-203 bamA UW LPXTG-motif cell wall anchor domain protein
HNFAHIGG_01025 0.0 bamA UW LPXTG-motif cell wall anchor domain protein
HNFAHIGG_01026 0.0 M domain protein
HNFAHIGG_01027 3.8e-299
HNFAHIGG_01028 8.7e-110 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HNFAHIGG_01029 3.7e-119 3.6.1.55 F NUDIX domain
HNFAHIGG_01030 7.4e-66 S Putative adhesin
HNFAHIGG_01031 2.2e-249 brnQ U Component of the transport system for branched-chain amino acids
HNFAHIGG_01032 1.8e-11 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HNFAHIGG_01033 2.7e-32 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HNFAHIGG_01034 5.9e-17 L Plasmid pRiA4b ORF-3-like protein
HNFAHIGG_01035 5.2e-68 K HxlR family
HNFAHIGG_01036 7.9e-48
HNFAHIGG_01037 5e-218 4.2.1.6, 5.1.2.2 M Mandelate racemase muconate lactonizing enzyme
HNFAHIGG_01038 6.1e-77 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HNFAHIGG_01039 2.3e-116 cylA V ABC transporter
HNFAHIGG_01040 9.9e-91 cylB V ABC-2 type transporter
HNFAHIGG_01041 5.7e-45 K LytTr DNA-binding domain
HNFAHIGG_01042 5.3e-39 S Protein of unknown function (DUF3021)
HNFAHIGG_01043 5.5e-71 yphH S Cupin domain
HNFAHIGG_01044 1.7e-187 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HNFAHIGG_01045 1.2e-35 uidA 3.2.1.31 G Belongs to the glycosyl hydrolase 2 family
HNFAHIGG_01046 4.5e-33 mta K helix_turn_helix, mercury resistance
HNFAHIGG_01047 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HNFAHIGG_01048 2.9e-120 lmrA 3.6.3.44 V ABC transporter
HNFAHIGG_01049 1.3e-151 C Aldo keto reductase
HNFAHIGG_01051 9.2e-101 K Transcriptional regulator C-terminal region
HNFAHIGG_01052 5.1e-231 E Alpha/beta hydrolase of unknown function (DUF1100)
HNFAHIGG_01053 2.1e-117 GM NAD(P)H-binding
HNFAHIGG_01054 5e-213 mdt(A) EGP Major facilitator Superfamily
HNFAHIGG_01055 3.2e-60 S Sulfite exporter TauE/SafE
HNFAHIGG_01056 1.9e-32 G Major facilitator Superfamily
HNFAHIGG_01057 1.4e-264 npr 1.11.1.1 C NADH oxidase
HNFAHIGG_01058 2e-77 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HNFAHIGG_01059 3.4e-169 yobV1 K WYL domain
HNFAHIGG_01060 9.1e-68 S pyridoxamine 5-phosphate
HNFAHIGG_01061 1.3e-21 cylB V ABC-2 type transporter
HNFAHIGG_01062 8e-49 K LytTr DNA-binding domain
HNFAHIGG_01063 3.2e-55 S Protein of unknown function (DUF3021)
HNFAHIGG_01064 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
HNFAHIGG_01065 1.8e-34 copZ C Heavy-metal-associated domain
HNFAHIGG_01066 4e-93 dps P Belongs to the Dps family
HNFAHIGG_01067 7.5e-112 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HNFAHIGG_01068 1.2e-22 K Acetyltransferase (GNAT) family
HNFAHIGG_01069 9.5e-39 K Acetyltransferase (GNAT) family
HNFAHIGG_01070 6.1e-129 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
HNFAHIGG_01071 2.9e-73 K Transcriptional regulator
HNFAHIGG_01072 2.6e-67 ogt 2.1.1.63 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
HNFAHIGG_01073 2.7e-85 XK27_09675 K Acetyltransferase (GNAT) domain
HNFAHIGG_01074 3.5e-120 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HNFAHIGG_01075 1.4e-242 yrvN L AAA C-terminal domain
HNFAHIGG_01076 3e-34 4.1.1.45 S Amidohydrolase
HNFAHIGG_01077 1.6e-58 4.1.1.45 S Amidohydrolase
HNFAHIGG_01078 1e-117 ybhL S Belongs to the BI1 family
HNFAHIGG_01079 6.2e-27
HNFAHIGG_01080 6.2e-39 ropB K Helix-turn-helix domain
HNFAHIGG_01081 4.5e-144
HNFAHIGG_01082 7.4e-188 S ABC-2 family transporter protein
HNFAHIGG_01083 5.1e-119 V ATPases associated with a variety of cellular activities
HNFAHIGG_01084 5.5e-160 C Aldo/keto reductase family
HNFAHIGG_01085 2.1e-160 akr5f 1.1.1.346 S reductase
HNFAHIGG_01086 3.3e-123 magIII L Base excision DNA repair protein, HhH-GPD family
HNFAHIGG_01087 2.6e-109 lacA 2.3.1.79 S Transferase hexapeptide repeat
HNFAHIGG_01088 8.9e-116 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HNFAHIGG_01089 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HNFAHIGG_01090 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HNFAHIGG_01091 4.1e-178 K Transcriptional regulator
HNFAHIGG_01092 2.8e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
HNFAHIGG_01093 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HNFAHIGG_01094 7.7e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HNFAHIGG_01095 1.5e-124 yoaK S Protein of unknown function (DUF1275)
HNFAHIGG_01096 4.1e-203 xerS L Belongs to the 'phage' integrase family
HNFAHIGG_01097 2.3e-159 K Transcriptional regulator
HNFAHIGG_01098 8.3e-151
HNFAHIGG_01099 1.6e-146 degV S EDD domain protein, DegV family
HNFAHIGG_01100 3.8e-64
HNFAHIGG_01101 0.0 FbpA K Fibronectin-binding protein
HNFAHIGG_01102 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
HNFAHIGG_01103 3.3e-197 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HNFAHIGG_01104 1.7e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HNFAHIGG_01105 2.3e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HNFAHIGG_01106 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HNFAHIGG_01107 9.9e-58
HNFAHIGG_01108 2.9e-173 degV S DegV family
HNFAHIGG_01109 3.1e-239 cpdA S Calcineurin-like phosphoesterase
HNFAHIGG_01110 4.5e-216 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HNFAHIGG_01111 7.1e-69 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HNFAHIGG_01112 7.2e-106 ypsA S Belongs to the UPF0398 family
HNFAHIGG_01113 5.9e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HNFAHIGG_01114 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HNFAHIGG_01115 1.2e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HNFAHIGG_01116 1.9e-115 dnaD L DnaD domain protein
HNFAHIGG_01117 2.9e-259 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HNFAHIGG_01118 1.4e-89 ypmB S Protein conserved in bacteria
HNFAHIGG_01119 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HNFAHIGG_01120 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HNFAHIGG_01121 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HNFAHIGG_01122 4.4e-169 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
HNFAHIGG_01123 1.9e-175 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HNFAHIGG_01124 5.4e-203 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HNFAHIGG_01125 5.2e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HNFAHIGG_01126 6.2e-272 V ABC-type multidrug transport system, ATPase and permease components
HNFAHIGG_01127 9.5e-289 V ABC-type multidrug transport system, ATPase and permease components
HNFAHIGG_01128 5.7e-156 G Transmembrane secretion effector
HNFAHIGG_01129 6.4e-124 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
HNFAHIGG_01130 1.2e-98 5.4.2.11 G Phosphoglycerate mutase family
HNFAHIGG_01131 4.4e-82 6.3.3.2 S ASCH
HNFAHIGG_01132 2.4e-144 2.4.2.3 F Phosphorylase superfamily
HNFAHIGG_01133 1.4e-136 2.4.2.3 F Phosphorylase superfamily
HNFAHIGG_01134 4.2e-41 3.6.1.55 F NUDIX domain
HNFAHIGG_01135 1.2e-138 2.7.1.89 M Phosphotransferase enzyme family
HNFAHIGG_01136 2.2e-82 S AAA domain
HNFAHIGG_01137 4.7e-132 S Alpha/beta hydrolase family
HNFAHIGG_01138 1.7e-113 XK27_07525 3.6.1.55 F NUDIX domain
HNFAHIGG_01139 6.8e-81 2.3.1.57 K Acetyltransferase (GNAT) family
HNFAHIGG_01140 4.4e-92 rimL J Acetyltransferase (GNAT) domain
HNFAHIGG_01141 2.5e-43
HNFAHIGG_01142 1.4e-50 S endonuclease activity
HNFAHIGG_01143 7e-18 S Fic/DOC family
HNFAHIGG_01144 3.3e-124
HNFAHIGG_01145 1e-57
HNFAHIGG_01146 1.2e-46 S MazG-like family
HNFAHIGG_01147 3.5e-138 S Protein of unknown function (DUF2785)
HNFAHIGG_01148 1e-70 K Acetyltransferase (GNAT) domain
HNFAHIGG_01149 1.1e-48
HNFAHIGG_01150 3.6e-280 V ABC transporter transmembrane region
HNFAHIGG_01151 4.3e-83 C nitroreductase
HNFAHIGG_01152 4.6e-291 V ABC-type multidrug transport system, ATPase and permease components
HNFAHIGG_01153 4.9e-148 ropB K Helix-turn-helix domain
HNFAHIGG_01154 1.6e-128 qmcA O prohibitin homologues
HNFAHIGG_01155 8.6e-137 S Protein of unknown function (DUF975)
HNFAHIGG_01156 8.2e-54 K sequence-specific DNA binding
HNFAHIGG_01157 1e-09 K sequence-specific DNA binding
HNFAHIGG_01158 1.7e-104 speG J Acetyltransferase (GNAT) domain
HNFAHIGG_01159 2.7e-137
HNFAHIGG_01160 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
HNFAHIGG_01161 6.6e-71 rpiB 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
HNFAHIGG_01162 9.3e-49
HNFAHIGG_01163 4.5e-26
HNFAHIGG_01164 5.5e-118 drgA C nitroreductase
HNFAHIGG_01165 2.7e-217 G Protein of unknown function (DUF4038)
HNFAHIGG_01166 2e-158 I alpha/beta hydrolase fold
HNFAHIGG_01167 8.5e-115 celB U The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HNFAHIGG_01168 5.3e-278 G isomerase
HNFAHIGG_01169 2.3e-163 purR13 K Bacterial regulatory proteins, lacI family
HNFAHIGG_01170 2.3e-140 2.2.1.1 G Transketolase, thiamine diphosphate binding domain
HNFAHIGG_01171 5.5e-159 tktA 2.2.1.1 G Transketolase, pyrimidine binding domain
HNFAHIGG_01172 6.1e-218 glpK_1 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HNFAHIGG_01173 1.3e-154 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HNFAHIGG_01174 1.3e-229 hom1 1.1.1.3 E homoserine dehydrogenase
HNFAHIGG_01175 5.4e-278 thrC 4.2.3.1 E Threonine synthase
HNFAHIGG_01176 2.6e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HNFAHIGG_01177 1.7e-254 lysC 2.7.2.4 E Belongs to the aspartokinase family
HNFAHIGG_01178 0.0 pepO 3.4.24.71 O Peptidase family M13
HNFAHIGG_01179 9.8e-23
HNFAHIGG_01180 1.5e-66 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HNFAHIGG_01181 3.9e-244 ubiX 2.5.1.129, 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HNFAHIGG_01182 2.8e-51 K LysR substrate binding domain
HNFAHIGG_01183 1.7e-91 S Protein of unknown function (DUF554)
HNFAHIGG_01184 1.1e-173 XK27_06780 V ABC transporter permease
HNFAHIGG_01185 4.4e-278 XK27_06780 V ABC transporter permease
HNFAHIGG_01186 2.9e-128 XK27_06785 V ABC transporter, ATP-binding protein
HNFAHIGG_01187 6.3e-125 alkD L DNA alkylation repair enzyme
HNFAHIGG_01188 4.2e-245 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HNFAHIGG_01189 1.4e-231 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HNFAHIGG_01190 5e-104 pncA Q Isochorismatase family
HNFAHIGG_01191 9.6e-92 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HNFAHIGG_01192 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HNFAHIGG_01193 1.6e-210 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HNFAHIGG_01194 1.6e-241 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HNFAHIGG_01195 1e-179 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HNFAHIGG_01196 2.1e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HNFAHIGG_01197 4.4e-169 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HNFAHIGG_01198 1.4e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HNFAHIGG_01199 7.1e-118 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HNFAHIGG_01200 6.8e-303 I Protein of unknown function (DUF2974)
HNFAHIGG_01201 7.6e-149 yxeH S hydrolase
HNFAHIGG_01202 7.8e-159 XK27_05540 S DUF218 domain
HNFAHIGG_01203 3.6e-49 ybjQ S Belongs to the UPF0145 family
HNFAHIGG_01204 2.2e-233 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
HNFAHIGG_01205 1.1e-165
HNFAHIGG_01206 1.6e-129
HNFAHIGG_01207 2.3e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HNFAHIGG_01208 2.3e-21
HNFAHIGG_01209 1.3e-108
HNFAHIGG_01210 1.8e-137
HNFAHIGG_01211 4.7e-123 skfE V ATPases associated with a variety of cellular activities
HNFAHIGG_01212 9.6e-59 yvoA_1 K Transcriptional regulator, GntR family
HNFAHIGG_01213 2.5e-244 pepT 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HNFAHIGG_01214 2.7e-151 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HNFAHIGG_01215 1.4e-119 trmK 2.1.1.217 S SAM-dependent methyltransferase
HNFAHIGG_01216 2.9e-199 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HNFAHIGG_01217 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HNFAHIGG_01218 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HNFAHIGG_01219 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HNFAHIGG_01220 1.6e-137 recO L Involved in DNA repair and RecF pathway recombination
HNFAHIGG_01221 1.3e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HNFAHIGG_01222 1.2e-91 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HNFAHIGG_01223 4.7e-174 phoH T phosphate starvation-inducible protein PhoH
HNFAHIGG_01224 4.1e-40 yqeY S YqeY-like protein
HNFAHIGG_01225 1.5e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HNFAHIGG_01226 3.9e-156 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HNFAHIGG_01227 1.3e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HNFAHIGG_01228 3.9e-104 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HNFAHIGG_01229 1.2e-143 E GDSL-like Lipase/Acylhydrolase family
HNFAHIGG_01230 4.4e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HNFAHIGG_01231 3e-223 patA 2.6.1.1 E Aminotransferase
HNFAHIGG_01232 3.9e-30
HNFAHIGG_01233 2.6e-161 htpX O Peptidase family M48
HNFAHIGG_01234 5.8e-76 S HIRAN
HNFAHIGG_01236 5.9e-188 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HNFAHIGG_01237 2.6e-117 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HNFAHIGG_01238 2e-163 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HNFAHIGG_01239 1.8e-208 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HNFAHIGG_01240 1.7e-210 KQ helix_turn_helix, mercury resistance
HNFAHIGG_01241 2.4e-06
HNFAHIGG_01244 5.8e-100 L Reverse transcriptase (RNA-dependent DNA polymerase)
HNFAHIGG_01245 2.7e-43 L reverse transcriptase
HNFAHIGG_01247 1.9e-182 S Membrane protein involved in the export of O-antigen and teichoic acid
HNFAHIGG_01248 3.6e-44 epsJ_2 M Glycosyltransferase like family 2
HNFAHIGG_01249 2.3e-28 S Polysaccharide pyruvyl transferase
HNFAHIGG_01250 1.4e-19 S Polysaccharide pyruvyl transferase
HNFAHIGG_01251 1.2e-80 S Core-2/I-Branching enzyme
HNFAHIGG_01252 8.3e-41 GT2 M transferase activity, transferring glycosyl groups
HNFAHIGG_01253 5.6e-30 S EpsG family
HNFAHIGG_01254 3.4e-120 M Glycosyl transferases group 1
HNFAHIGG_01255 1.5e-131 M Glycosyl transferases group 1
HNFAHIGG_01256 2.3e-119 rfbP M Bacterial sugar transferase
HNFAHIGG_01257 1.7e-142 ywqE 3.1.3.48 GM PHP domain protein
HNFAHIGG_01258 9e-120 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HNFAHIGG_01259 1e-127 epsB M biosynthesis protein
HNFAHIGG_01260 4.5e-159 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HNFAHIGG_01261 7.2e-75 K DNA-templated transcription, initiation
HNFAHIGG_01262 2.5e-158
HNFAHIGG_01263 5.3e-116 frnE Q DSBA-like thioredoxin domain
HNFAHIGG_01264 2.4e-218
HNFAHIGG_01265 1.7e-69 S Domain of unknown function (DUF4767)
HNFAHIGG_01266 7.3e-81
HNFAHIGG_01267 8.2e-87 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HNFAHIGG_01268 1.2e-103 engB D Necessary for normal cell division and for the maintenance of normal septation
HNFAHIGG_01269 1.5e-231 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HNFAHIGG_01270 1.5e-202 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HNFAHIGG_01271 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HNFAHIGG_01272 1.7e-159
HNFAHIGG_01273 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HNFAHIGG_01274 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HNFAHIGG_01275 7.5e-34 rpsT J Binds directly to 16S ribosomal RNA
HNFAHIGG_01276 3e-176 holA 2.7.7.7 L DNA polymerase III delta subunit
HNFAHIGG_01277 0.0 comEC S Competence protein ComEC
HNFAHIGG_01278 1.2e-78 comEA L Competence protein ComEA
HNFAHIGG_01279 2.5e-186 ylbL T Belongs to the peptidase S16 family
HNFAHIGG_01280 5.6e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HNFAHIGG_01281 7.2e-95 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HNFAHIGG_01282 1.3e-51 ylbG S UPF0298 protein
HNFAHIGG_01283 5.9e-211 ftsW D Belongs to the SEDS family
HNFAHIGG_01284 0.0 typA T GTP-binding protein TypA
HNFAHIGG_01285 2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HNFAHIGG_01286 3e-34 ykzG S Belongs to the UPF0356 family
HNFAHIGG_01287 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HNFAHIGG_01288 1e-173 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HNFAHIGG_01289 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HNFAHIGG_01290 5.1e-116 S Repeat protein
HNFAHIGG_01291 7.5e-123 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HNFAHIGG_01292 3.3e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HNFAHIGG_01293 1.6e-57 XK27_04120 S Putative amino acid metabolism
HNFAHIGG_01294 5.6e-214 iscS 2.8.1.7 E Aminotransferase class V
HNFAHIGG_01295 5.9e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HNFAHIGG_01297 9.7e-103 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HNFAHIGG_01298 2e-32 cspA K 'Cold-shock' DNA-binding domain
HNFAHIGG_01299 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HNFAHIGG_01300 7.8e-73 gpsB D DivIVA domain protein
HNFAHIGG_01301 1.3e-19 gpsB D DivIVA domain protein
HNFAHIGG_01302 2.6e-146 ylmH S S4 domain protein
HNFAHIGG_01303 2e-27 yggT S YGGT family
HNFAHIGG_01304 3.6e-73 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HNFAHIGG_01305 6e-231 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HNFAHIGG_01306 4.6e-239 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HNFAHIGG_01307 8.2e-154 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HNFAHIGG_01308 1.2e-210 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HNFAHIGG_01309 2.5e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HNFAHIGG_01310 1.6e-177 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HNFAHIGG_01311 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HNFAHIGG_01312 6.3e-55 ftsL D Cell division protein FtsL
HNFAHIGG_01313 1.3e-176 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HNFAHIGG_01314 4.1e-77 mraZ K Belongs to the MraZ family
HNFAHIGG_01315 6.1e-52 S Protein of unknown function (DUF3397)
HNFAHIGG_01316 3.6e-13 S Protein of unknown function (DUF4044)
HNFAHIGG_01317 6e-94 mreD
HNFAHIGG_01318 1.3e-143 mreC M Involved in formation and maintenance of cell shape
HNFAHIGG_01319 6.4e-166 mreB D cell shape determining protein MreB
HNFAHIGG_01320 6.1e-111 radC L DNA repair protein
HNFAHIGG_01321 1.9e-122 S Haloacid dehalogenase-like hydrolase
HNFAHIGG_01322 8.2e-235 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HNFAHIGG_01323 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HNFAHIGG_01324 0.0 3.6.3.8 P P-type ATPase
HNFAHIGG_01325 1.2e-82 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HNFAHIGG_01326 3.9e-116 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HNFAHIGG_01327 9.5e-124 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HNFAHIGG_01328 7.2e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HNFAHIGG_01329 2.1e-216 iscS2 2.8.1.7 E Aminotransferase class V
HNFAHIGG_01330 2.5e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HNFAHIGG_01332 1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HNFAHIGG_01333 2.3e-81 yueI S Protein of unknown function (DUF1694)
HNFAHIGG_01334 1.8e-237 rarA L recombination factor protein RarA
HNFAHIGG_01336 5.2e-81 usp6 T universal stress protein
HNFAHIGG_01337 4.7e-224 rodA D Belongs to the SEDS family
HNFAHIGG_01338 1.3e-34 S Protein of unknown function (DUF2969)
HNFAHIGG_01339 2e-51 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HNFAHIGG_01340 2.5e-15 S DNA-directed RNA polymerase subunit beta
HNFAHIGG_01341 2.2e-179 mbl D Cell shape determining protein MreB Mrl
HNFAHIGG_01342 2e-30 ywzB S Protein of unknown function (DUF1146)
HNFAHIGG_01343 1.1e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HNFAHIGG_01344 3.3e-248 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HNFAHIGG_01345 3.1e-170 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HNFAHIGG_01346 5.1e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HNFAHIGG_01347 5.7e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HNFAHIGG_01348 2.6e-43 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HNFAHIGG_01349 1.2e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HNFAHIGG_01350 1.6e-126 atpB C it plays a direct role in the translocation of protons across the membrane
HNFAHIGG_01351 1.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HNFAHIGG_01352 1.2e-188 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HNFAHIGG_01353 1.1e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HNFAHIGG_01354 1e-196 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HNFAHIGG_01355 5.5e-112 tdk 2.7.1.21 F thymidine kinase
HNFAHIGG_01356 1.6e-260 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
HNFAHIGG_01357 9.4e-189 ampC V Beta-lactamase
HNFAHIGG_01360 4.1e-72
HNFAHIGG_01361 6.5e-212 EGP Major facilitator Superfamily
HNFAHIGG_01362 1.6e-260 pgi 5.3.1.9 G Belongs to the GPI family
HNFAHIGG_01363 1e-105 vanZ V VanZ like family
HNFAHIGG_01364 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HNFAHIGG_01365 3.1e-270 T PhoQ Sensor
HNFAHIGG_01366 9.9e-129 K Transcriptional regulatory protein, C terminal
HNFAHIGG_01367 1.2e-67 S SdpI/YhfL protein family
HNFAHIGG_01368 1.5e-191 manA 5.3.1.8 G mannose-6-phosphate isomerase
HNFAHIGG_01369 8.2e-79 patB 4.4.1.8 E Aminotransferase, class I
HNFAHIGG_01370 8.6e-76 M Protein of unknown function (DUF3737)
HNFAHIGG_01371 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
HNFAHIGG_01372 6.5e-22 xre K Helix-turn-helix domain
HNFAHIGG_01374 1.3e-10
HNFAHIGG_01376 7.3e-225 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HNFAHIGG_01377 1.5e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
HNFAHIGG_01378 4.7e-88 comGF U Putative Competence protein ComGF
HNFAHIGG_01379 5.1e-08
HNFAHIGG_01380 3.7e-67
HNFAHIGG_01381 1.1e-36 comGC U Required for transformation and DNA binding
HNFAHIGG_01382 1.4e-176 comGB NU type II secretion system
HNFAHIGG_01383 5.8e-180 comGA NU Type II IV secretion system protein
HNFAHIGG_01384 1.5e-132 yebC K Transcriptional regulatory protein
HNFAHIGG_01385 3.4e-94 S VanZ like family
HNFAHIGG_01386 3.1e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HNFAHIGG_01387 5.5e-161 znuA P Belongs to the bacterial solute-binding protein 9 family
HNFAHIGG_01388 2.5e-149 yisY 1.11.1.10 S Alpha/beta hydrolase family
HNFAHIGG_01389 1.4e-114
HNFAHIGG_01390 1.8e-178 S Putative adhesin
HNFAHIGG_01391 5.3e-62 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HNFAHIGG_01392 2.3e-66 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HNFAHIGG_01393 1.6e-146 S Sucrose-6F-phosphate phosphohydrolase
HNFAHIGG_01394 1e-254 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HNFAHIGG_01395 8.1e-174 ybbR S YbbR-like protein
HNFAHIGG_01396 3.4e-152 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HNFAHIGG_01397 1.3e-209 potD P ABC transporter
HNFAHIGG_01398 2.2e-137 potC P ABC transporter permease
HNFAHIGG_01399 4.6e-130 potB P ABC transporter permease
HNFAHIGG_01400 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HNFAHIGG_01401 4.4e-166 murB 1.3.1.98 M Cell wall formation
HNFAHIGG_01402 1e-98 dnaQ 2.7.7.7 L DNA polymerase III
HNFAHIGG_01403 5e-84 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HNFAHIGG_01404 2.5e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HNFAHIGG_01405 4.1e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HNFAHIGG_01406 8e-157 ycsE S Sucrose-6F-phosphate phosphohydrolase
HNFAHIGG_01407 2.9e-93
HNFAHIGG_01408 2.3e-91
HNFAHIGG_01410 1e-107 3.2.2.20 K acetyltransferase
HNFAHIGG_01411 2.3e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HNFAHIGG_01412 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HNFAHIGG_01413 2.5e-28 secG U Preprotein translocase
HNFAHIGG_01414 5.3e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HNFAHIGG_01415 1.9e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HNFAHIGG_01416 6e-227 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HNFAHIGG_01417 3.2e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HNFAHIGG_01418 2.3e-187 cggR K Putative sugar-binding domain
HNFAHIGG_01420 1.2e-277 ycaM E amino acid
HNFAHIGG_01421 1e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HNFAHIGG_01422 6.2e-171 whiA K May be required for sporulation
HNFAHIGG_01423 4.4e-194 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HNFAHIGG_01424 6e-160 rapZ S Displays ATPase and GTPase activities
HNFAHIGG_01425 1.1e-90 S Short repeat of unknown function (DUF308)
HNFAHIGG_01426 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HNFAHIGG_01427 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HNFAHIGG_01428 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HNFAHIGG_01429 6.7e-192 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HNFAHIGG_01430 7.4e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HNFAHIGG_01431 4.2e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HNFAHIGG_01432 1.6e-180 lacR K Transcriptional regulator
HNFAHIGG_01433 8.1e-249 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HNFAHIGG_01434 5.1e-164 yvgN C Aldo keto reductase
HNFAHIGG_01436 3.3e-74 M domain protein
HNFAHIGG_01438 1e-42
HNFAHIGG_01440 3.4e-28
HNFAHIGG_01441 1.8e-129 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HNFAHIGG_01442 5e-07
HNFAHIGG_01444 1.1e-118 repB EP Plasmid replication protein
HNFAHIGG_01445 7.1e-11
HNFAHIGG_01446 2.2e-152 L Belongs to the 'phage' integrase family
HNFAHIGG_01447 5.7e-115 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HNFAHIGG_01448 1.4e-20 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HNFAHIGG_01449 3.4e-94 K acetyltransferase
HNFAHIGG_01450 6.6e-61 psiE S Phosphate-starvation-inducible E
HNFAHIGG_01451 1.4e-133 S Putative ABC-transporter type IV
HNFAHIGG_01452 1.5e-109 M LysM domain protein
HNFAHIGG_01453 4.8e-99 M LysM domain protein
HNFAHIGG_01455 1.7e-59 yjgN S Bacterial protein of unknown function (DUF898)
HNFAHIGG_01456 1.4e-189 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
HNFAHIGG_01458 1.8e-145 K SIS domain
HNFAHIGG_01459 2e-166 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
HNFAHIGG_01462 2.1e-51 P Rhodanese Homology Domain
HNFAHIGG_01463 1.4e-100
HNFAHIGG_01464 7.4e-80
HNFAHIGG_01465 9.5e-124 gntR1 K UTRA
HNFAHIGG_01466 1.5e-67 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
HNFAHIGG_01467 1.5e-132 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HNFAHIGG_01468 2.5e-203 csaB M Glycosyl transferases group 1
HNFAHIGG_01469 0.0 tuaG GT2 M Glycosyltransferase like family 2
HNFAHIGG_01470 2e-285 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HNFAHIGG_01471 1e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HNFAHIGG_01472 0.0 pacL 3.6.3.8 P P-type ATPase
HNFAHIGG_01473 2.4e-284 V ABC transporter transmembrane region
HNFAHIGG_01474 7e-147
HNFAHIGG_01475 2.8e-226 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HNFAHIGG_01476 2.1e-258 epsU S Polysaccharide biosynthesis protein
HNFAHIGG_01477 3.5e-134 M Glycosyltransferase sugar-binding region containing DXD motif
HNFAHIGG_01478 6.7e-86 ydcK S Belongs to the SprT family
HNFAHIGG_01480 2.6e-101 S ECF transporter, substrate-specific component
HNFAHIGG_01481 2.7e-114 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
HNFAHIGG_01482 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HNFAHIGG_01483 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HNFAHIGG_01484 1.7e-207 camS S sex pheromone
HNFAHIGG_01485 4.3e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HNFAHIGG_01486 1.5e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HNFAHIGG_01487 1e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HNFAHIGG_01488 7.3e-169 yegS 2.7.1.107 G Lipid kinase
HNFAHIGG_01490 2.8e-151 S hydrolase
HNFAHIGG_01491 2.4e-151 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
HNFAHIGG_01492 1.9e-137 asp1 S Accessory Sec system protein Asp1
HNFAHIGG_01493 9.8e-190 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
HNFAHIGG_01495 3.9e-40 asp3 S Accessory Sec secretory system ASP3
HNFAHIGG_01496 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HNFAHIGG_01497 1e-210 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HNFAHIGG_01498 1.6e-188 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HNFAHIGG_01502 5.2e-93 GT2,GT4 M family 8
HNFAHIGG_01503 2.1e-97 M family 8
HNFAHIGG_01504 1.1e-230 M family 8
HNFAHIGG_01505 1.9e-108 cpsJ S glycosyl transferase family 2
HNFAHIGG_01506 6.2e-124 nss M transferase activity, transferring glycosyl groups
HNFAHIGG_01507 3.1e-152 nss M transferase activity, transferring glycosyl groups
HNFAHIGG_01508 7.8e-94 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
HNFAHIGG_01509 8.1e-88 S ECF transporter, substrate-specific component
HNFAHIGG_01510 7.2e-65 S Domain of unknown function (DUF4430)
HNFAHIGG_01511 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
HNFAHIGG_01512 3.2e-119 ybhL S Belongs to the BI1 family
HNFAHIGG_01513 7e-142 cbiQ P cobalt transport
HNFAHIGG_01514 7.7e-310 ykoD P ABC transporter, ATP-binding protein
HNFAHIGG_01515 3.3e-95 S UPF0397 protein
HNFAHIGG_01516 2.8e-162 salL 2.5.1.63, 2.5.1.94 K S-adenosyl-l-methionine hydroxide adenosyltransferase
HNFAHIGG_01517 4.4e-242 nhaC C Na H antiporter NhaC
HNFAHIGG_01518 4.6e-126 mutF V ABC transporter, ATP-binding protein
HNFAHIGG_01519 9.6e-121 spaE S ABC-2 family transporter protein
HNFAHIGG_01520 2.2e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HNFAHIGG_01521 2e-194 V Beta-lactamase
HNFAHIGG_01522 1.8e-139 neo 2.7.1.87, 2.7.1.95 F Belongs to the aminoglycoside phosphotransferase family
HNFAHIGG_01523 1.3e-121 S Bacteriophage abortive infection AbiH
HNFAHIGG_01524 5e-93 3.6.1.55 L NUDIX domain
HNFAHIGG_01525 1.3e-66
HNFAHIGG_01526 2.1e-257 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HNFAHIGG_01528 3.2e-158 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HNFAHIGG_01529 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HNFAHIGG_01530 3.3e-56 yheA S Belongs to the UPF0342 family
HNFAHIGG_01531 4.7e-227 yhaO L Ser Thr phosphatase family protein
HNFAHIGG_01532 0.0 L AAA domain
HNFAHIGG_01533 1.6e-185 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
HNFAHIGG_01534 4.3e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HNFAHIGG_01535 4.6e-26 S YtxH-like protein
HNFAHIGG_01536 2e-64
HNFAHIGG_01537 1.2e-76 hit FG Scavenger mRNA decapping enzyme C-term binding
HNFAHIGG_01538 2.4e-133 ecsA V ABC transporter, ATP-binding protein
HNFAHIGG_01539 1.8e-226 ecsB U ABC transporter
HNFAHIGG_01540 3e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HNFAHIGG_01541 4e-71 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HNFAHIGG_01542 1.8e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HNFAHIGG_01543 7.4e-123 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HNFAHIGG_01544 1.6e-129 ymfC K UTRA
HNFAHIGG_01545 1.8e-253 3.5.1.18 E Peptidase family M20/M25/M40
HNFAHIGG_01546 3.3e-180 aspG 3.4.19.5, 3.5.1.1, 3.5.1.26 E Asparaginase
HNFAHIGG_01547 5e-93 S Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)
HNFAHIGG_01548 1.9e-197 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HNFAHIGG_01549 1.2e-117 cutC P Participates in the control of copper homeostasis
HNFAHIGG_01550 2.8e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HNFAHIGG_01551 2.6e-74 K UTRA
HNFAHIGG_01552 4e-69 rmaI K Transcriptional regulator
HNFAHIGG_01553 3.5e-210 EGP Major facilitator Superfamily
HNFAHIGG_01554 1.9e-225 ygeX 4.3.1.15, 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
HNFAHIGG_01555 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HNFAHIGG_01556 4.8e-159 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HNFAHIGG_01557 1e-102 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HNFAHIGG_01558 5.9e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HNFAHIGG_01559 2.9e-246 dnaB L Replication initiation and membrane attachment
HNFAHIGG_01560 2.7e-163 dnaI L Primosomal protein DnaI
HNFAHIGG_01561 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HNFAHIGG_01562 4e-87 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HNFAHIGG_01563 2.4e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HNFAHIGG_01564 6.6e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HNFAHIGG_01565 8.9e-145 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HNFAHIGG_01566 5.1e-90 yqeG S HAD phosphatase, family IIIA
HNFAHIGG_01567 1e-209 yqeH S Ribosome biogenesis GTPase YqeH
HNFAHIGG_01568 4.4e-120 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HNFAHIGG_01569 1.7e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HNFAHIGG_01570 8.2e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HNFAHIGG_01571 6e-216 ylbM S Belongs to the UPF0348 family
HNFAHIGG_01572 2.9e-96 yceD S Uncharacterized ACR, COG1399
HNFAHIGG_01573 1.1e-130 K response regulator
HNFAHIGG_01574 1.9e-281 arlS 2.7.13.3 T Histidine kinase
HNFAHIGG_01575 1.1e-170 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HNFAHIGG_01576 3.8e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HNFAHIGG_01577 9.6e-138 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HNFAHIGG_01578 7.3e-64 yodB K Transcriptional regulator, HxlR family
HNFAHIGG_01579 8.1e-204 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HNFAHIGG_01580 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HNFAHIGG_01581 1.7e-204 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HNFAHIGG_01582 4e-65 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HNFAHIGG_01583 0.0 S membrane
HNFAHIGG_01584 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HNFAHIGG_01585 7.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HNFAHIGG_01586 5.6e-87 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HNFAHIGG_01587 2.4e-119 gluP 3.4.21.105 S Rhomboid family
HNFAHIGG_01588 6e-35 yqgQ S Bacterial protein of unknown function (DUF910)
HNFAHIGG_01589 1.5e-57 yqhL P Rhodanese-like protein
HNFAHIGG_01590 1.1e-18 S Protein of unknown function (DUF3042)
HNFAHIGG_01591 1.2e-166 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HNFAHIGG_01592 1.1e-261 glnA 6.3.1.2 E glutamine synthetase
HNFAHIGG_01593 2.8e-205 EGP Major facilitator Superfamily
HNFAHIGG_01594 4.3e-152 S haloacid dehalogenase-like hydrolase
HNFAHIGG_01595 1.1e-07
HNFAHIGG_01596 4.8e-179 D Alpha beta
HNFAHIGG_01597 1.9e-214 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
HNFAHIGG_01598 2.5e-220 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HNFAHIGG_01599 1.6e-216 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HNFAHIGG_01600 1.1e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HNFAHIGG_01601 1.6e-143 recX 2.4.1.337 GT4 S Regulatory protein RecX
HNFAHIGG_01602 2.4e-112 ygaC J Belongs to the UPF0374 family
HNFAHIGG_01603 1.4e-89
HNFAHIGG_01604 3e-78
HNFAHIGG_01605 6.2e-157 hlyX S Transporter associated domain
HNFAHIGG_01606 7.9e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HNFAHIGG_01607 1.1e-43 XK27_09445 S Domain of unknown function (DUF1827)
HNFAHIGG_01608 0.0 clpE O Belongs to the ClpA ClpB family
HNFAHIGG_01609 6.9e-26
HNFAHIGG_01610 4.2e-40 ptsH G phosphocarrier protein HPR
HNFAHIGG_01611 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HNFAHIGG_01612 6.7e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HNFAHIGG_01613 5.5e-118 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HNFAHIGG_01614 1.7e-162 coiA 3.6.4.12 S Competence protein
HNFAHIGG_01615 4.5e-106 yjbH Q Thioredoxin
HNFAHIGG_01616 7.4e-112 yjbK S CYTH
HNFAHIGG_01617 6.7e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
HNFAHIGG_01618 4e-150 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HNFAHIGG_01619 3.7e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HNFAHIGG_01620 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
HNFAHIGG_01621 3.9e-234 N Uncharacterized conserved protein (DUF2075)
HNFAHIGG_01622 1.2e-199 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HNFAHIGG_01623 9.9e-67 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HNFAHIGG_01624 5.4e-212 yubA S AI-2E family transporter
HNFAHIGG_01625 2.7e-105 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HNFAHIGG_01626 4.6e-76 WQ51_03320 S Protein of unknown function (DUF1149)
HNFAHIGG_01627 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HNFAHIGG_01628 2.2e-229 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
HNFAHIGG_01629 2.9e-232 S Peptidase M16
HNFAHIGG_01630 1.6e-129 IQ Enoyl-(Acyl carrier protein) reductase
HNFAHIGG_01631 4.3e-125 ymfM S Helix-turn-helix domain
HNFAHIGG_01632 1.8e-96 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HNFAHIGG_01633 1.9e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HNFAHIGG_01634 2e-209 rny S Endoribonuclease that initiates mRNA decay
HNFAHIGG_01635 5e-191 tagO 2.7.8.33, 2.7.8.35 M transferase
HNFAHIGG_01636 2.5e-118 yvyE 3.4.13.9 S YigZ family
HNFAHIGG_01637 1.5e-239 comFA L Helicase C-terminal domain protein
HNFAHIGG_01638 2.2e-125 comFC S Competence protein
HNFAHIGG_01639 4.5e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HNFAHIGG_01640 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HNFAHIGG_01641 6.2e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HNFAHIGG_01642 2.5e-35
HNFAHIGG_01643 3.3e-175 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HNFAHIGG_01644 5.4e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HNFAHIGG_01645 2.6e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HNFAHIGG_01646 6e-174 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HNFAHIGG_01647 1.4e-216 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HNFAHIGG_01648 1.1e-101 J Acetyltransferase (GNAT) domain
HNFAHIGG_01649 5.8e-106 yjbF S SNARE associated Golgi protein
HNFAHIGG_01650 1e-150 I alpha/beta hydrolase fold
HNFAHIGG_01651 2.7e-115 hipB K Helix-turn-helix
HNFAHIGG_01652 2.1e-19 hipB K Helix-turn-helix
HNFAHIGG_01653 8e-260 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HNFAHIGG_01654 6e-180
HNFAHIGG_01655 2.1e-123 S SNARE associated Golgi protein
HNFAHIGG_01656 1.7e-132 cof S haloacid dehalogenase-like hydrolase
HNFAHIGG_01657 0.0 ydgH S MMPL family
HNFAHIGG_01658 1.8e-96 yobS K Bacterial regulatory proteins, tetR family
HNFAHIGG_01659 2.1e-166 3.5.2.6 V Beta-lactamase enzyme family
HNFAHIGG_01660 1.2e-166 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
HNFAHIGG_01661 5.3e-80 yjcF S Acetyltransferase (GNAT) domain
HNFAHIGG_01662 1.7e-96 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HNFAHIGG_01663 1.1e-77 yybA 2.3.1.57 K Transcriptional regulator
HNFAHIGG_01664 8.1e-50 ypaA S Protein of unknown function (DUF1304)
HNFAHIGG_01665 3e-240 G Bacterial extracellular solute-binding protein
HNFAHIGG_01666 1.1e-253 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
HNFAHIGG_01667 5e-148 gtsC P Binding-protein-dependent transport system inner membrane component
HNFAHIGG_01668 9.5e-158 gtsB P ABC-type sugar transport systems, permease components
HNFAHIGG_01669 7.1e-203 malK P ATPases associated with a variety of cellular activities
HNFAHIGG_01670 3.2e-283 pipD E Dipeptidase
HNFAHIGG_01671 6.7e-132 endA F DNA RNA non-specific endonuclease
HNFAHIGG_01672 1.3e-148 dkg S reductase
HNFAHIGG_01673 1.1e-201 ltrA S Bacterial low temperature requirement A protein (LtrA)
HNFAHIGG_01674 1.6e-182 dnaQ 2.7.7.7 L EXOIII
HNFAHIGG_01675 7.5e-141 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HNFAHIGG_01676 3.1e-113 yviA S Protein of unknown function (DUF421)
HNFAHIGG_01677 7.5e-74 S Protein of unknown function (DUF3290)
HNFAHIGG_01678 2.5e-247 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HNFAHIGG_01679 1.9e-95 S PAS domain
HNFAHIGG_01680 6.3e-145 pnuC H nicotinamide mononucleotide transporter
HNFAHIGG_01681 0.0 M domain protein
HNFAHIGG_01682 2e-43 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HNFAHIGG_01683 7e-36 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HNFAHIGG_01684 2.8e-102 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HNFAHIGG_01685 5.1e-128 S PAS domain
HNFAHIGG_01686 7.9e-239 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HNFAHIGG_01687 8.2e-215 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
HNFAHIGG_01688 8e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HNFAHIGG_01689 0.0 dnaX 2.4.99.16, 2.7.7.7 GH13 M domain protein
HNFAHIGG_01690 5e-69
HNFAHIGG_01691 0.0 uvrA3 L excinuclease ABC, A subunit
HNFAHIGG_01692 0.0 oppA E ABC transporter substrate-binding protein
HNFAHIGG_01693 6.4e-160 EG EamA-like transporter family
HNFAHIGG_01694 3.8e-284 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HNFAHIGG_01695 0.0 bglP 2.7.1.211 G phosphotransferase system
HNFAHIGG_01696 7.1e-150 licT K CAT RNA binding domain
HNFAHIGG_01697 0.0 fhaB M Rib/alpha-like repeat
HNFAHIGG_01698 3.7e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HNFAHIGG_01699 1.9e-163 coaA 2.7.1.33 F Pantothenic acid kinase
HNFAHIGG_01700 6.2e-105 E GDSL-like Lipase/Acylhydrolase
HNFAHIGG_01701 2.7e-244 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HNFAHIGG_01702 4.9e-82 rarA L MgsA AAA+ ATPase C terminal
HNFAHIGG_01703 2.3e-122 K Helix-turn-helix domain, rpiR family
HNFAHIGG_01704 1.1e-135 yvpB S Peptidase_C39 like family
HNFAHIGG_01705 0.0 helD 3.6.4.12 L DNA helicase
HNFAHIGG_01706 1.2e-117 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HNFAHIGG_01708 0.0 3.6.3.8 P ATPase, P-type (transporting), HAD superfamily, subfamily IC
HNFAHIGG_01709 5.1e-254 3.4.16.4 M ErfK YbiS YcfS YnhG
HNFAHIGG_01710 1.5e-144 rpiR1 K Helix-turn-helix domain, rpiR family
HNFAHIGG_01711 6.9e-127 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HNFAHIGG_01712 0.0 ptsG 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
HNFAHIGG_01713 3.2e-149 xth 3.1.11.2 L exodeoxyribonuclease III
HNFAHIGG_01714 1.6e-52
HNFAHIGG_01715 5.3e-25
HNFAHIGG_01716 8e-125 pgm3 G Phosphoglycerate mutase family
HNFAHIGG_01717 0.0 V FtsX-like permease family
HNFAHIGG_01718 2.2e-134 cysA V ABC transporter, ATP-binding protein
HNFAHIGG_01719 7.3e-280 E amino acid
HNFAHIGG_01720 2.4e-234 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HNFAHIGG_01721 2.5e-233 S Putative peptidoglycan binding domain
HNFAHIGG_01722 4e-90 M NlpC P60 family protein
HNFAHIGG_01724 1.3e-99 gmk2 2.7.4.8 F Guanylate kinase
HNFAHIGG_01725 9e-44
HNFAHIGG_01726 8.3e-274 S O-antigen ligase like membrane protein
HNFAHIGG_01727 4.1e-110
HNFAHIGG_01728 2.9e-81 nrdI F NrdI Flavodoxin like
HNFAHIGG_01729 7.4e-180 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HNFAHIGG_01730 5.3e-81
HNFAHIGG_01731 4.7e-60 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HNFAHIGG_01732 1.8e-40
HNFAHIGG_01733 9.6e-80 S Threonine/Serine exporter, ThrE
HNFAHIGG_01734 7.5e-138 thrE S Putative threonine/serine exporter
HNFAHIGG_01735 9e-284 S ABC transporter, ATP-binding protein
HNFAHIGG_01736 1.4e-60
HNFAHIGG_01737 4e-38
HNFAHIGG_01738 3e-212 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HNFAHIGG_01739 0.0 pepF E oligoendopeptidase F
HNFAHIGG_01740 1.4e-69 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HNFAHIGG_01741 4.1e-257 lctP C L-lactate permease
HNFAHIGG_01742 6.7e-134 znuB U ABC 3 transport family
HNFAHIGG_01743 1.1e-116 fhuC P ABC transporter
HNFAHIGG_01744 2.4e-156 psaA P Belongs to the bacterial solute-binding protein 9 family
HNFAHIGG_01745 1.6e-42 K helix_turn_helix, Arsenical Resistance Operon Repressor
HNFAHIGG_01746 6.9e-139 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
HNFAHIGG_01747 0.0 M domain protein
HNFAHIGG_01748 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
HNFAHIGG_01749 6.9e-167 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HNFAHIGG_01750 1.5e-135 fruR K DeoR C terminal sensor domain
HNFAHIGG_01751 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HNFAHIGG_01752 3.8e-221 natB CP ABC-2 family transporter protein
HNFAHIGG_01753 3.4e-166 natA S ABC transporter, ATP-binding protein
HNFAHIGG_01754 2.3e-144 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HNFAHIGG_01755 2.2e-306 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HNFAHIGG_01756 2.9e-202 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
HNFAHIGG_01757 7.4e-121 K response regulator
HNFAHIGG_01758 0.0 V ABC transporter
HNFAHIGG_01759 8.7e-296 V ABC transporter, ATP-binding protein
HNFAHIGG_01760 4.9e-143 XK27_01040 S Protein of unknown function (DUF1129)
HNFAHIGG_01761 7.5e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HNFAHIGG_01762 1.3e-43 yyzM S Bacterial protein of unknown function (DUF951)
HNFAHIGG_01763 2.2e-154 spo0J K Belongs to the ParB family
HNFAHIGG_01764 4.4e-138 soj D Sporulation initiation inhibitor
HNFAHIGG_01765 2.1e-144 noc K Belongs to the ParB family
HNFAHIGG_01766 1.2e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HNFAHIGG_01767 3.2e-95 cvpA S Colicin V production protein
HNFAHIGG_01768 3.6e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HNFAHIGG_01769 4.4e-149 3.1.3.48 T Tyrosine phosphatase family
HNFAHIGG_01770 1.7e-198 4.2.1.126 S Bacterial protein of unknown function (DUF871)
HNFAHIGG_01771 6.4e-99 azr 1.5.1.36 S NADPH-dependent FMN reductase
HNFAHIGG_01772 2e-97 nqr 1.5.1.36 S NADPH-dependent FMN reductase
HNFAHIGG_01773 1.8e-84 K WHG domain
HNFAHIGG_01774 8e-38
HNFAHIGG_01775 1.1e-275 pipD E Dipeptidase
HNFAHIGG_01776 1.7e-295 arbB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HNFAHIGG_01777 3.8e-297 2.7.1.211 G phosphotransferase system
HNFAHIGG_01778 4.2e-158 K CAT RNA binding domain
HNFAHIGG_01779 6.8e-119 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HNFAHIGG_01780 1.1e-173 hrtB V ABC transporter permease
HNFAHIGG_01781 1.9e-92 ygfC K Bacterial regulatory proteins, tetR family
HNFAHIGG_01782 3.5e-111 G phosphoglycerate mutase
HNFAHIGG_01783 9.4e-115 G Phosphoglycerate mutase family
HNFAHIGG_01784 1.6e-140 aroD S Alpha/beta hydrolase family
HNFAHIGG_01785 7.7e-106 S Protein of unknown function (DUF975)
HNFAHIGG_01786 3.9e-139 S Belongs to the UPF0246 family
HNFAHIGG_01787 2.2e-52
HNFAHIGG_01788 6.7e-130
HNFAHIGG_01789 5.6e-161 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HNFAHIGG_01790 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
HNFAHIGG_01791 3.4e-143 3.4.16.4, 3.5.2.6 V Beta-lactamase enzyme family
HNFAHIGG_01792 6.3e-154 ybbH_2 K Helix-turn-helix domain, rpiR family
HNFAHIGG_01793 5.8e-171 2.7.7.12 C Domain of unknown function (DUF4931)
HNFAHIGG_01794 1.2e-52 aroD 1.1.1.25, 4.2.1.10 E 3-dehydroquinate dehydratase activity
HNFAHIGG_01795 1.1e-156
HNFAHIGG_01796 3e-226 mdtG EGP Major facilitator Superfamily
HNFAHIGG_01797 1.6e-123 puuD S peptidase C26
HNFAHIGG_01798 1.1e-292 V ABC transporter transmembrane region
HNFAHIGG_01799 9e-92 ymdB S Macro domain protein
HNFAHIGG_01800 0.0 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
HNFAHIGG_01801 1.1e-299 scrB 3.2.1.26 GH32 G invertase
HNFAHIGG_01802 1.2e-185 scrR K Transcriptional regulator, LacI family
HNFAHIGG_01803 3e-147 ptp2 3.1.3.48 T Tyrosine phosphatase family
HNFAHIGG_01804 7.6e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HNFAHIGG_01805 7.1e-132 cobQ S glutamine amidotransferase
HNFAHIGG_01806 4.2e-256 yfnA E Amino Acid
HNFAHIGG_01807 1.6e-163 EG EamA-like transporter family
HNFAHIGG_01808 2.8e-193 asnA 6.3.1.1 F aspartate--ammonia ligase
HNFAHIGG_01809 3.5e-79 S CAAX protease self-immunity
HNFAHIGG_01810 1.4e-107 S CAAX protease self-immunity
HNFAHIGG_01811 2.5e-240 steT_1 E amino acid
HNFAHIGG_01812 4.5e-137 puuD S peptidase C26
HNFAHIGG_01813 1.2e-223 yifK E Amino acid permease
HNFAHIGG_01814 1.8e-251 yifK E Amino acid permease
HNFAHIGG_01815 1.8e-65 manO S Domain of unknown function (DUF956)
HNFAHIGG_01816 5.6e-172 manN G system, mannose fructose sorbose family IID component
HNFAHIGG_01817 1.3e-124 manY G PTS system
HNFAHIGG_01818 9.5e-186 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HNFAHIGG_01820 0.0 lhr L DEAD DEAH box helicase
HNFAHIGG_01821 1.9e-250 P P-loop Domain of unknown function (DUF2791)
HNFAHIGG_01822 0.0 S TerB-C domain
HNFAHIGG_01823 6.4e-104 4.1.1.44 S Carboxymuconolactone decarboxylase family
HNFAHIGG_01824 4.3e-71
HNFAHIGG_01825 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HNFAHIGG_01826 4.3e-39 cycA E Amino acid permease
HNFAHIGG_01827 3.3e-173 cycA E Amino acid permease
HNFAHIGG_01828 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HNFAHIGG_01829 4.5e-183 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HNFAHIGG_01830 7.1e-200 cpoA GT4 M Glycosyltransferase, group 1 family protein
HNFAHIGG_01831 9.9e-219 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
HNFAHIGG_01843 8.5e-60
HNFAHIGG_01860 2e-110 S Plasmid replication protein
HNFAHIGG_01861 3.9e-17

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)