ORF_ID e_value Gene_name EC_number CAZy COGs Description
OFPHMMLE_00001 5.3e-192 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OFPHMMLE_00002 0.0 S domain, Protein
OFPHMMLE_00003 6.1e-113 S domain, Protein
OFPHMMLE_00004 1.1e-130 treR K UTRA
OFPHMMLE_00005 0.0 treB 2.7.1.211 G phosphotransferase system
OFPHMMLE_00006 7.3e-64 yodB K Transcriptional regulator, HxlR family
OFPHMMLE_00007 3.1e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OFPHMMLE_00008 2.8e-140 rpsB J Belongs to the universal ribosomal protein uS2 family
OFPHMMLE_00009 5e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OFPHMMLE_00010 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
OFPHMMLE_00011 3.4e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
OFPHMMLE_00012 2.7e-134 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OFPHMMLE_00013 2.8e-48 V ABC transporter transmembrane region
OFPHMMLE_00014 0.0 pacL 3.6.3.8 P P-type ATPase
OFPHMMLE_00015 2.7e-126 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
OFPHMMLE_00016 2.7e-26
OFPHMMLE_00017 2.9e-212 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
OFPHMMLE_00018 9.5e-178 ccpA K catabolite control protein A
OFPHMMLE_00019 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M Penicillin binding protein transpeptidase domain
OFPHMMLE_00020 2.4e-275 pepV 3.5.1.18 E dipeptidase PepV
OFPHMMLE_00021 8e-268 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
OFPHMMLE_00022 2e-55
OFPHMMLE_00023 3.6e-268 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
OFPHMMLE_00024 9.1e-98 yutD S Protein of unknown function (DUF1027)
OFPHMMLE_00025 3.6e-148 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
OFPHMMLE_00026 3.1e-42 M Plasmid recombination enzyme
OFPHMMLE_00028 5.2e-19 S Plasmid replication protein
OFPHMMLE_00029 8.2e-296 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
OFPHMMLE_00030 8.8e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OFPHMMLE_00032 1.7e-123 liaI S membrane
OFPHMMLE_00033 1e-78 XK27_02470 K LytTr DNA-binding domain
OFPHMMLE_00034 3.9e-117 yhiD S MgtC family
OFPHMMLE_00036 7.9e-114 gph 3.1.3.18 S HAD hydrolase, family IA, variant
OFPHMMLE_00037 3.2e-116 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
OFPHMMLE_00038 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
OFPHMMLE_00039 0.0 M domain protein
OFPHMMLE_00040 2.7e-135 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
OFPHMMLE_00041 1e-122 thiN 2.7.6.2 H thiamine pyrophosphokinase
OFPHMMLE_00042 1.6e-25 rpmB J Belongs to the bacterial ribosomal protein bL28 family
OFPHMMLE_00043 1.4e-57 asp S Asp23 family, cell envelope-related function
OFPHMMLE_00044 8.1e-307 yloV S DAK2 domain fusion protein YloV
OFPHMMLE_00045 2.3e-75 K Acetyltransferase (GNAT) domain
OFPHMMLE_00046 1e-248 ynbB 4.4.1.1 P aluminum resistance
OFPHMMLE_00047 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
OFPHMMLE_00048 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
OFPHMMLE_00049 2e-52 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
OFPHMMLE_00050 8.5e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
OFPHMMLE_00051 1e-133 gmuR K UTRA
OFPHMMLE_00052 5.6e-117 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OFPHMMLE_00053 1.9e-166 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OFPHMMLE_00054 3.4e-42 S Domain of unknown function (DUF3284)
OFPHMMLE_00055 8.7e-57 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
OFPHMMLE_00056 0.0 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
OFPHMMLE_00057 4.8e-292 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
OFPHMMLE_00058 2.4e-68 yslB S Protein of unknown function (DUF2507)
OFPHMMLE_00059 6.6e-53 trxA O Belongs to the thioredoxin family
OFPHMMLE_00060 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
OFPHMMLE_00061 1.6e-91 cvpA S Colicin V production protein
OFPHMMLE_00062 1.8e-50 yrzB S Belongs to the UPF0473 family
OFPHMMLE_00063 1.4e-72 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OFPHMMLE_00064 2.6e-42 yrzL S Belongs to the UPF0297 family
OFPHMMLE_00065 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OFPHMMLE_00066 1.5e-229 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
OFPHMMLE_00067 6.6e-184 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
OFPHMMLE_00068 1.5e-132 XK27_08440 K UTRA domain
OFPHMMLE_00069 5.7e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
OFPHMMLE_00070 3.8e-87 uspA T universal stress protein
OFPHMMLE_00072 9.8e-169 phnD P Phosphonate ABC transporter
OFPHMMLE_00073 1e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
OFPHMMLE_00074 7.7e-120 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
OFPHMMLE_00075 1.8e-124 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
OFPHMMLE_00076 6e-238 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
OFPHMMLE_00077 4.5e-17 L Plasmid pRiA4b ORF-3-like protein
OFPHMMLE_00078 2.9e-70 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
OFPHMMLE_00079 1.4e-11 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
OFPHMMLE_00080 2.4e-248 brnQ U Component of the transport system for branched-chain amino acids
OFPHMMLE_00081 2.3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
OFPHMMLE_00082 3.8e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
OFPHMMLE_00083 3.6e-252 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
OFPHMMLE_00084 3.8e-99 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OFPHMMLE_00085 1.3e-110 M LysM domain protein
OFPHMMLE_00086 3.9e-93 M LysM domain protein
OFPHMMLE_00088 1.7e-59 yjgN S Bacterial protein of unknown function (DUF898)
OFPHMMLE_00089 5.1e-44 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
OFPHMMLE_00090 1.1e-79 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
OFPHMMLE_00091 1.8e-59 K DeoR C terminal sensor domain
OFPHMMLE_00092 3.5e-50 pts36A 2.7.1.200, 2.7.1.202 G phosphoenolpyruvate-dependent sugar phosphotransferase system
OFPHMMLE_00093 2.1e-09 sgcB 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
OFPHMMLE_00094 1e-193 pts36C G iic component
OFPHMMLE_00096 2.3e-110 4.1.2.17 G Class II Aldolase and Adducin N-terminal domain
OFPHMMLE_00097 1.1e-78 S PAS domain
OFPHMMLE_00098 8.8e-245 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
OFPHMMLE_00099 6.4e-73 S Protein of unknown function (DUF3290)
OFPHMMLE_00100 1.3e-111 yviA S Protein of unknown function (DUF421)
OFPHMMLE_00101 7.5e-141 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OFPHMMLE_00102 3e-181 dnaQ 2.7.7.7 L EXOIII
OFPHMMLE_00103 8.9e-139 glcR K DeoR C terminal sensor domain
OFPHMMLE_00104 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
OFPHMMLE_00106 2.3e-113 E Belongs to the SOS response-associated peptidase family
OFPHMMLE_00107 2.6e-194 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
OFPHMMLE_00108 4.3e-91 comEB 3.5.4.12 F MafB19-like deaminase
OFPHMMLE_00109 4.7e-100 S TPM domain
OFPHMMLE_00110 1.1e-24 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
OFPHMMLE_00111 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
OFPHMMLE_00112 2.7e-182 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
OFPHMMLE_00114 2.3e-78 dnaE 2.7.7.7 L DNA polymerase
OFPHMMLE_00115 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
OFPHMMLE_00116 5.1e-72
OFPHMMLE_00117 1.4e-67 L Phage terminase, small subunit
OFPHMMLE_00118 2e-86 S HNH endonuclease
OFPHMMLE_00119 3.2e-75 arpU S Phage transcriptional regulator, ArpU family
OFPHMMLE_00121 2.9e-37 S VRR_NUC
OFPHMMLE_00122 1.1e-121 XK27_01040 S Protein of unknown function (DUF1129)
OFPHMMLE_00123 1.1e-219 V ABC transporter, ATP-binding protein
OFPHMMLE_00124 6.8e-41 V ABC transporter, ATP-binding protein
OFPHMMLE_00125 2e-135 rpl K Helix-turn-helix domain, rpiR family
OFPHMMLE_00126 2.9e-83 D nuclear chromosome segregation
OFPHMMLE_00127 1.1e-241 L AAA domain
OFPHMMLE_00128 1.6e-230 yhaO L Ser Thr phosphatase family protein
OFPHMMLE_00129 3.3e-56 yheA S Belongs to the UPF0342 family
OFPHMMLE_00130 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
OFPHMMLE_00131 3.6e-162 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OFPHMMLE_00133 1.3e-259 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
OFPHMMLE_00134 1.3e-66
OFPHMMLE_00135 2e-94 3.6.1.55 L NUDIX domain
OFPHMMLE_00136 2.2e-153 neo 2.7.1.87, 2.7.1.95 F Belongs to the aminoglycoside phosphotransferase family
OFPHMMLE_00137 8.5e-139 V Beta-lactamase
OFPHMMLE_00138 0.0 pepN 3.4.11.2 E aminopeptidase
OFPHMMLE_00139 4.2e-50
OFPHMMLE_00140 9.6e-189 V ABC transporter transmembrane region
OFPHMMLE_00141 1.3e-148 glnH ET ABC transporter
OFPHMMLE_00142 2.7e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
OFPHMMLE_00143 3.5e-38 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
OFPHMMLE_00144 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OFPHMMLE_00145 8.4e-134 fruR K DeoR C terminal sensor domain
OFPHMMLE_00146 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
OFPHMMLE_00147 7.7e-73 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
OFPHMMLE_00148 1.1e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OFPHMMLE_00149 3.1e-289 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OFPHMMLE_00150 6.1e-153 ydgH S MMPL family
OFPHMMLE_00151 3.1e-144 ydgH S MMPL family
OFPHMMLE_00152 5.6e-87 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OFPHMMLE_00153 7.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
OFPHMMLE_00154 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
OFPHMMLE_00155 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
OFPHMMLE_00156 2.8e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OFPHMMLE_00157 1.3e-96 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
OFPHMMLE_00158 1.2e-188 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
OFPHMMLE_00159 1.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OFPHMMLE_00160 1.6e-126 atpB C it plays a direct role in the translocation of protons across the membrane
OFPHMMLE_00161 2.1e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OFPHMMLE_00162 5.9e-51 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OFPHMMLE_00163 5.7e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OFPHMMLE_00164 5.1e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OFPHMMLE_00165 3.1e-170 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OFPHMMLE_00166 3.3e-248 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OFPHMMLE_00167 1.1e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
OFPHMMLE_00168 2e-30 ywzB S Protein of unknown function (DUF1146)
OFPHMMLE_00169 2.2e-179 mbl D Cell shape determining protein MreB Mrl
OFPHMMLE_00170 4.7e-64 S Domain of unknown function (DUF4430)
OFPHMMLE_00171 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
OFPHMMLE_00172 2.7e-234 G PTS system sugar-specific permease component
OFPHMMLE_00173 4.5e-269 G PTS system Galactitol-specific IIC component
OFPHMMLE_00174 0.0 clpE2 O AAA domain (Cdc48 subfamily)
OFPHMMLE_00175 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OFPHMMLE_00176 4.2e-217 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
OFPHMMLE_00196 3.2e-56 V Beta-lactamase
OFPHMMLE_00197 8.4e-63
OFPHMMLE_00198 0.0 L helicase activity
OFPHMMLE_00199 6.4e-227 K DNA binding
OFPHMMLE_00200 0.0 res 2.1.1.72, 3.1.21.5 L Type III restriction enzyme, res subunit
OFPHMMLE_00201 7.2e-251 mod 2.1.1.72, 3.1.21.5 L DNA methylase
OFPHMMLE_00202 7.4e-39 K Cro/C1-type HTH DNA-binding domain
OFPHMMLE_00203 3.1e-79
OFPHMMLE_00204 1.9e-32 G Major facilitator Superfamily
OFPHMMLE_00205 4.1e-264 npr 1.11.1.1 C NADH oxidase
OFPHMMLE_00206 2.3e-63 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
OFPHMMLE_00207 4.1e-30 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
OFPHMMLE_00208 4.3e-163 S Aldo keto reductase
OFPHMMLE_00210 4.6e-224 S Sterol carrier protein domain
OFPHMMLE_00211 3e-116 ywnB S NAD(P)H-binding
OFPHMMLE_00212 5.1e-116 S Repeat protein
OFPHMMLE_00213 2e-123 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
OFPHMMLE_00214 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
OFPHMMLE_00215 1.3e-64 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
OFPHMMLE_00216 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
OFPHMMLE_00217 2.2e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OFPHMMLE_00218 6e-236 pbuX F xanthine permease
OFPHMMLE_00219 5.3e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
OFPHMMLE_00220 6.6e-134 K DNA-binding helix-turn-helix protein
OFPHMMLE_00221 1.6e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
OFPHMMLE_00223 9.4e-65 K Helix-turn-helix
OFPHMMLE_00224 9.7e-281 glnP P ABC transporter permease
OFPHMMLE_00225 1.9e-138 glnQ E ABC transporter, ATP-binding protein
OFPHMMLE_00226 3.5e-28 L HNH nucleases
OFPHMMLE_00227 1.2e-209 rny S Endoribonuclease that initiates mRNA decay
OFPHMMLE_00228 2.7e-192 tagO 2.7.8.33, 2.7.8.35 M transferase
OFPHMMLE_00229 0.0 oppA E ABC transporter substrate-binding protein
OFPHMMLE_00230 1.7e-68 S Phage integrase family
OFPHMMLE_00231 8.2e-96 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OFPHMMLE_00232 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
OFPHMMLE_00233 9.3e-124 srtA 3.4.22.70 M sortase family
OFPHMMLE_00234 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
OFPHMMLE_00235 4.5e-171 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
OFPHMMLE_00236 0.0 dnaK O Heat shock 70 kDa protein
OFPHMMLE_00237 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
OFPHMMLE_00238 2.9e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OFPHMMLE_00239 1.8e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
OFPHMMLE_00240 7.4e-58 M Lysin motif
OFPHMMLE_00241 6.9e-26
OFPHMMLE_00242 1.2e-39 ptsH G phosphocarrier protein HPR
OFPHMMLE_00243 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OFPHMMLE_00244 1.7e-268 pts23C 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OFPHMMLE_00245 1.2e-282 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OFPHMMLE_00246 4.8e-22 M Phage tail tape measure protein TP901
OFPHMMLE_00248 2.1e-08 S Pfam:Phage_TTP_1
OFPHMMLE_00252 3.7e-37 S Phage gp6-like head-tail connector protein
OFPHMMLE_00253 7.3e-209 S peptidase activity
OFPHMMLE_00254 3.4e-113 S Clp protease
OFPHMMLE_00255 3e-162 S Phage portal protein
OFPHMMLE_00257 8.3e-241 S Phage Terminase
OFPHMMLE_00258 6.9e-19 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
OFPHMMLE_00259 1e-12
OFPHMMLE_00260 2.5e-159 lysA2 M Glycosyl hydrolases family 25
OFPHMMLE_00261 3.9e-50 S Bacteriophage holin of superfamily 6 (Holin_LLH)
OFPHMMLE_00262 2.2e-39
OFPHMMLE_00263 6.8e-61
OFPHMMLE_00265 1e-82
OFPHMMLE_00266 0.0 S N-acetylmuramoyl-L-alanine amidase activity
OFPHMMLE_00267 1e-91 S Uncharacterized protein conserved in bacteria (DUF2313)
OFPHMMLE_00268 5.2e-212 S Baseplate J-like protein
OFPHMMLE_00269 1.6e-61 S Protein of unknown function (DUF2634)
OFPHMMLE_00270 1.3e-54 S Protein of unknown function (DUF2577)
OFPHMMLE_00271 6.4e-201 S N-acetylmuramoyl-L-alanine amidase activity
OFPHMMLE_00272 4.7e-112 ygaU GH23 S protein containing LysM domain
OFPHMMLE_00273 3.1e-222 S phage tail tape measure protein
OFPHMMLE_00274 3.7e-67 S Pfam:Phage_TAC_5
OFPHMMLE_00275 2.4e-83 S Protein of unknown function (DUF2001)
OFPHMMLE_00276 4.8e-241 xkdK S Phage tail sheath C-terminal domain
OFPHMMLE_00277 8.6e-31
OFPHMMLE_00278 6.6e-69
OFPHMMLE_00279 2.1e-73
OFPHMMLE_00280 1.4e-62
OFPHMMLE_00281 3.6e-64
OFPHMMLE_00282 6.5e-182
OFPHMMLE_00283 8.9e-45 S Phage minor structural protein GP20
OFPHMMLE_00284 4.2e-188 S Phage Mu protein F like protein
OFPHMMLE_00285 3.3e-269 S Phage portal protein, SPP1 Gp6-like
OFPHMMLE_00286 3.1e-239 S DNA packaging
OFPHMMLE_00287 1.9e-87 S Terminase small subunit
OFPHMMLE_00288 8.6e-119
OFPHMMLE_00290 2.8e-119 C Domain of unknown function (DUF4145)
OFPHMMLE_00292 1e-47 K chromosome segregation
OFPHMMLE_00294 1.7e-96
OFPHMMLE_00295 3.5e-24
OFPHMMLE_00296 2.4e-25
OFPHMMLE_00297 4.2e-37
OFPHMMLE_00299 3.6e-79 rusA 3.1.22.4 L Endodeoxyribonuclease RusA
OFPHMMLE_00303 1.1e-30
OFPHMMLE_00304 8.5e-123 S DNA binding
OFPHMMLE_00306 3.7e-25 S sequence-specific DNA binding
OFPHMMLE_00307 1.5e-127 S calcium ion binding
OFPHMMLE_00308 6.6e-49 S Protein of unknown function (DUF1071)
OFPHMMLE_00310 1.5e-55
OFPHMMLE_00311 6.4e-14
OFPHMMLE_00315 6e-60 S Domain of unknown function (DUF771)
OFPHMMLE_00317 1.3e-54 xre K Helix-turn-helix domain
OFPHMMLE_00318 1.9e-80 S Pfam:Peptidase_M78
OFPHMMLE_00319 1.4e-86 S Domain of Unknown Function with PDB structure (DUF3862)
OFPHMMLE_00321 1.5e-123 S Phage integrase family
OFPHMMLE_00322 1.9e-62 P CorA-like Mg2+ transporter protein
OFPHMMLE_00323 0.0 tetP J elongation factor G
OFPHMMLE_00324 2.8e-224 mdtG EGP Major facilitator Superfamily
OFPHMMLE_00325 1.4e-34 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OFPHMMLE_00326 5.6e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OFPHMMLE_00327 7.7e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OFPHMMLE_00328 2.2e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
OFPHMMLE_00329 6.6e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OFPHMMLE_00330 3.6e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OFPHMMLE_00331 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OFPHMMLE_00332 5e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OFPHMMLE_00333 5.6e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OFPHMMLE_00334 2.2e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
OFPHMMLE_00335 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
OFPHMMLE_00336 2.2e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OFPHMMLE_00337 5.8e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
OFPHMMLE_00338 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OFPHMMLE_00339 1e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
OFPHMMLE_00340 3.5e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OFPHMMLE_00341 1.6e-157 hlyX S Transporter associated domain
OFPHMMLE_00342 7.9e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OFPHMMLE_00343 3.7e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
OFPHMMLE_00345 4.5e-76 S HIRAN
OFPHMMLE_00346 1.4e-65
OFPHMMLE_00347 4.4e-43
OFPHMMLE_00348 4.3e-283 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OFPHMMLE_00349 3.9e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
OFPHMMLE_00350 3.9e-37 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OFPHMMLE_00351 9.3e-250 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
OFPHMMLE_00352 1.7e-173 pbpX2 V Beta-lactamase
OFPHMMLE_00353 2e-214 lmrP E Major Facilitator Superfamily
OFPHMMLE_00354 2.1e-38
OFPHMMLE_00355 2.6e-239 pts13C 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OFPHMMLE_00356 2.8e-102 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
OFPHMMLE_00357 3.6e-252 yhdP S Transporter associated domain
OFPHMMLE_00358 2.3e-65
OFPHMMLE_00359 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
OFPHMMLE_00360 2.5e-189 ansA 3.5.1.1 EJ L-asparaginase, type I
OFPHMMLE_00361 6.4e-257 yjjP S Putative threonine/serine exporter
OFPHMMLE_00362 2.6e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
OFPHMMLE_00363 2.1e-260 frdC 1.3.5.4 C FAD binding domain
OFPHMMLE_00364 3.8e-265 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
OFPHMMLE_00365 2.8e-67 metI P ABC transporter permease
OFPHMMLE_00366 4e-93 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OFPHMMLE_00367 9.8e-79 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OFPHMMLE_00368 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
OFPHMMLE_00369 1.9e-145 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OFPHMMLE_00370 7.7e-102 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OFPHMMLE_00371 7.8e-167 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
OFPHMMLE_00372 5e-207 camS S sex pheromone
OFPHMMLE_00373 4.3e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OFPHMMLE_00374 1.5e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
OFPHMMLE_00375 1.5e-272 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OFPHMMLE_00376 7.3e-169 yegS 2.7.1.107 G Lipid kinase
OFPHMMLE_00378 9.6e-152 S hydrolase
OFPHMMLE_00379 1.2e-39 L hmm pf00665
OFPHMMLE_00380 2.3e-23 L hmm pf00665
OFPHMMLE_00381 4.4e-129 L Helix-turn-helix domain
OFPHMMLE_00382 2.1e-94 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
OFPHMMLE_00383 5.2e-19 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OFPHMMLE_00384 1.9e-76 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OFPHMMLE_00385 1.4e-23 rpmD J Ribosomal protein L30
OFPHMMLE_00386 1.3e-70 rplO J Binds to the 23S rRNA
OFPHMMLE_00387 4.6e-109 glnP P ABC transporter permease
OFPHMMLE_00388 1.6e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
OFPHMMLE_00389 5.3e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OFPHMMLE_00390 1.2e-132 S membrane transporter protein
OFPHMMLE_00391 2e-150 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
OFPHMMLE_00392 1.1e-77 3.5.2.6 V Beta-lactamase enzyme family
OFPHMMLE_00393 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
OFPHMMLE_00394 2e-169 V ABC transporter
OFPHMMLE_00395 7.4e-121 K response regulator
OFPHMMLE_00396 0.0 1.3.5.4 C FMN_bind
OFPHMMLE_00397 6.4e-38 S Protein of unknown function DUF262
OFPHMMLE_00398 1.3e-145 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
OFPHMMLE_00399 3.9e-19 yaaA S S4 domain
OFPHMMLE_00400 4.5e-208 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OFPHMMLE_00401 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OFPHMMLE_00402 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OFPHMMLE_00403 9.4e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
OFPHMMLE_00404 1.7e-82 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
OFPHMMLE_00405 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OFPHMMLE_00406 4.4e-37 S YtxH-like protein
OFPHMMLE_00407 2e-64
OFPHMMLE_00408 2.4e-77 hit FG Scavenger mRNA decapping enzyme C-term binding
OFPHMMLE_00409 0.0 typA T GTP-binding protein TypA
OFPHMMLE_00410 1.7e-36
OFPHMMLE_00411 0.0 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
OFPHMMLE_00412 2.3e-289 scrB 3.2.1.26 GH32 G invertase
OFPHMMLE_00413 1e-184 scrR K Transcriptional regulator, LacI family
OFPHMMLE_00414 4.4e-53 G polysaccharide catabolic process
OFPHMMLE_00415 4.5e-59 G PTS system mannose/fructose/sorbose family IID component
OFPHMMLE_00416 1.7e-36 G PTS system sorbose-specific iic component
OFPHMMLE_00417 9.5e-205 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
OFPHMMLE_00418 9.2e-243 uup S ABC transporter, ATP-binding protein
OFPHMMLE_00419 8.3e-68
OFPHMMLE_00420 2.8e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
OFPHMMLE_00421 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
OFPHMMLE_00422 7.3e-64 arsC 1.20.4.1 P Belongs to the ArsC family
OFPHMMLE_00423 9e-113 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
OFPHMMLE_00424 2.7e-163 dnaI L Primosomal protein DnaI
OFPHMMLE_00425 9.1e-206 dnaB L Replication initiation and membrane attachment
OFPHMMLE_00426 1.1e-106 S Oxidoreductase family, NAD-binding Rossmann fold
OFPHMMLE_00427 0.0 yjbQ P TrkA C-terminal domain protein
OFPHMMLE_00428 1.1e-144 fruK 2.7.1.11, 2.7.1.56 G pfkB family carbohydrate kinase
OFPHMMLE_00429 1.5e-250 lysA2 M Glycosyl hydrolases family 25
OFPHMMLE_00430 8.6e-265 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
OFPHMMLE_00431 1.4e-34 S Protein of unknown function (DUF2922)
OFPHMMLE_00432 0.0 4.2.1.53 S Myosin-crossreactive antigen
OFPHMMLE_00433 2.8e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
OFPHMMLE_00434 3e-34 ykzG S Belongs to the UPF0356 family
OFPHMMLE_00435 1.3e-182 S DUF218 domain
OFPHMMLE_00438 4.8e-216 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OFPHMMLE_00439 3.2e-259 qacA EGP Major facilitator Superfamily
OFPHMMLE_00440 5.9e-82 3.6.1.27 I Acid phosphatase homologues
OFPHMMLE_00441 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
OFPHMMLE_00442 3.9e-301 ytgP S Polysaccharide biosynthesis protein
OFPHMMLE_00443 4e-65 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
OFPHMMLE_00444 2.9e-204 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OFPHMMLE_00445 3.6e-73 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
OFPHMMLE_00446 3.7e-233 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OFPHMMLE_00447 4.3e-118 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
OFPHMMLE_00448 1.6e-130 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
OFPHMMLE_00449 5.4e-147 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
OFPHMMLE_00450 7.3e-83
OFPHMMLE_00451 3.1e-275 S Calcineurin-like phosphoesterase
OFPHMMLE_00452 0.0 asnB 6.3.5.4 E Asparagine synthase
OFPHMMLE_00453 7.3e-266 yxbA 6.3.1.12 S ATP-grasp enzyme
OFPHMMLE_00454 2.5e-44 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OFPHMMLE_00455 4.6e-181 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OFPHMMLE_00456 0.0 kup P Transport of potassium into the cell
OFPHMMLE_00457 1.4e-66 fhaB 4.3.1.7 UW LPXTG-motif cell wall anchor domain protein
OFPHMMLE_00458 1e-248 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OFPHMMLE_00459 2.7e-227
OFPHMMLE_00460 3.8e-290 L Recombinase
OFPHMMLE_00461 9.1e-101 L Recombinase zinc beta ribbon domain
OFPHMMLE_00462 3.1e-164 L Recombinase zinc beta ribbon domain
OFPHMMLE_00463 4.3e-36
OFPHMMLE_00464 2.7e-144 M Glycosyl hydrolases family 25
OFPHMMLE_00465 3e-69 S Bacteriophage holin family
OFPHMMLE_00466 9e-68 S Phage head-tail joining protein
OFPHMMLE_00467 4.3e-43 S Phage gp6-like head-tail connector protein
OFPHMMLE_00468 6.3e-221 S Phage capsid family
OFPHMMLE_00469 2.9e-122 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
OFPHMMLE_00470 2.5e-247 S Phage portal protein
OFPHMMLE_00471 2.6e-302 S overlaps another CDS with the same product name
OFPHMMLE_00472 6.2e-31 S Domain of unknown function (DUF5049)
OFPHMMLE_00473 2.3e-113 S Psort location Cytoplasmic, score
OFPHMMLE_00474 2.2e-245 2.1.1.72 KL DNA methylase
OFPHMMLE_00475 1.4e-36
OFPHMMLE_00476 2.8e-87
OFPHMMLE_00477 4.3e-258 L SNF2 family N-terminal domain
OFPHMMLE_00478 2.4e-46 S VRR_NUC
OFPHMMLE_00479 0.0 S Phage plasmid primase, P4
OFPHMMLE_00480 2.8e-69 S Psort location Cytoplasmic, score
OFPHMMLE_00481 0.0 polA_2 2.7.7.7 L DNA polymerase
OFPHMMLE_00482 4.9e-99 S Protein of unknown function (DUF2815)
OFPHMMLE_00483 1.6e-221 L Protein of unknown function (DUF2800)
OFPHMMLE_00484 3.4e-12
OFPHMMLE_00485 6e-23
OFPHMMLE_00487 0.0 pepO 3.4.24.71 O Peptidase family M13
OFPHMMLE_00488 8.9e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
OFPHMMLE_00489 5.1e-69 3.6.1.27 I Acid phosphatase homologues
OFPHMMLE_00490 1.2e-32 3.1.21.3 V Type I restriction modification DNA specificity domain
OFPHMMLE_00491 8.3e-84 S Putative adhesin
OFPHMMLE_00492 5.2e-113 udk 2.7.1.48 F Cytidine monophosphokinase
OFPHMMLE_00493 5.6e-205 EGP Major facilitator superfamily
OFPHMMLE_00495 6.8e-56 S Enterocin A Immunity
OFPHMMLE_00496 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
OFPHMMLE_00497 4.8e-159 rssA S Phospholipase, patatin family
OFPHMMLE_00498 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
OFPHMMLE_00499 3.3e-124 skfE V ATPases associated with a variety of cellular activities
OFPHMMLE_00500 9.6e-59 yvoA_1 K Transcriptional regulator, GntR family
OFPHMMLE_00501 3e-101 pepT 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
OFPHMMLE_00502 2.6e-120 pepT 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
OFPHMMLE_00503 3.2e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OFPHMMLE_00504 2.5e-121 trmK 2.1.1.217 S SAM-dependent methyltransferase
OFPHMMLE_00505 2.9e-199 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
OFPHMMLE_00506 3.7e-301 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
OFPHMMLE_00507 4.1e-286 E Amino acid permease
OFPHMMLE_00508 9.7e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OFPHMMLE_00509 3.8e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OFPHMMLE_00510 1e-81 yueI S Protein of unknown function (DUF1694)
OFPHMMLE_00511 1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OFPHMMLE_00513 4.5e-31 yajC U Preprotein translocase
OFPHMMLE_00514 6e-216 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
OFPHMMLE_00515 3.9e-221 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
OFPHMMLE_00516 2.9e-218 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
OFPHMMLE_00517 3.5e-263 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OFPHMMLE_00518 7.8e-146 recX 2.4.1.337 GT4 S Regulatory protein RecX
OFPHMMLE_00519 2.4e-112 ygaC J Belongs to the UPF0374 family
OFPHMMLE_00520 4.9e-90
OFPHMMLE_00521 1.4e-56 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OFPHMMLE_00522 8.1e-174 ybbR S YbbR-like protein
OFPHMMLE_00523 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OFPHMMLE_00524 2.4e-62
OFPHMMLE_00525 1.4e-103 fhaB M Rib/alpha-like repeat
OFPHMMLE_00526 1.7e-103 S Uncharacterised protein family (UPF0236)
OFPHMMLE_00527 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
OFPHMMLE_00528 2.4e-240 cycA E Amino acid permease
OFPHMMLE_00529 4.3e-70 pnb C nitroreductase
OFPHMMLE_00530 4.1e-14 pnb C nitroreductase
OFPHMMLE_00531 1.4e-216 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OFPHMMLE_00534 3.6e-73 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OFPHMMLE_00535 2.3e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OFPHMMLE_00536 2.7e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OFPHMMLE_00537 5e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OFPHMMLE_00538 6.7e-161 map 3.4.11.18 E Methionine Aminopeptidase
OFPHMMLE_00539 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
OFPHMMLE_00540 0.0 3.6.3.8 P P-type ATPase
OFPHMMLE_00541 4.1e-110 L PFAM Integrase catalytic
OFPHMMLE_00542 2.5e-181 XK27_09600 V ABC transporter, ATP-binding protein
OFPHMMLE_00543 2.1e-226 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
OFPHMMLE_00544 1.9e-69 macB_3 V ABC transporter, ATP-binding protein
OFPHMMLE_00545 8.7e-270 cydA 1.10.3.14 C ubiquinol oxidase
OFPHMMLE_00546 2.2e-182 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
OFPHMMLE_00547 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
OFPHMMLE_00548 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
OFPHMMLE_00549 7.8e-109 S Protein of unknown function (DUF969)
OFPHMMLE_00550 1.2e-114 pepO 3.4.24.71 O Peptidase family M13
OFPHMMLE_00551 4.8e-257 lysC 2.7.2.4 E Belongs to the aspartokinase family
OFPHMMLE_00552 2.1e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OFPHMMLE_00553 1e-281 thrC 4.2.3.1 E Threonine synthase
OFPHMMLE_00554 7.7e-230 hom1 1.1.1.3 E homoserine dehydrogenase
OFPHMMLE_00555 3.3e-158 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
OFPHMMLE_00556 2.7e-210 pepA E M42 glutamyl aminopeptidase
OFPHMMLE_00558 9.8e-160 yeaE S Aldo/keto reductase family
OFPHMMLE_00559 3.6e-19 S PD-(D/E)XK nuclease family transposase
OFPHMMLE_00560 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OFPHMMLE_00561 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OFPHMMLE_00562 3.4e-94 ropB K Transcriptional regulator
OFPHMMLE_00563 1.2e-201 EGP Major facilitator Superfamily
OFPHMMLE_00564 5.2e-284 clcA P chloride
OFPHMMLE_00565 6.6e-270 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OFPHMMLE_00566 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
OFPHMMLE_00567 6.1e-53 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
OFPHMMLE_00568 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OFPHMMLE_00569 6.1e-148 tatD L hydrolase, TatD family
OFPHMMLE_00570 1.9e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OFPHMMLE_00571 4.7e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
OFPHMMLE_00572 7.4e-36 veg S Biofilm formation stimulator VEG
OFPHMMLE_00573 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
OFPHMMLE_00574 1.1e-219 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OFPHMMLE_00575 2.4e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OFPHMMLE_00576 1.2e-174 yvdE K helix_turn _helix lactose operon repressor
OFPHMMLE_00577 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
OFPHMMLE_00578 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
OFPHMMLE_00579 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
OFPHMMLE_00580 7.1e-113 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
OFPHMMLE_00581 3.6e-210 msmX P Belongs to the ABC transporter superfamily
OFPHMMLE_00582 3.4e-189 L COG2963 Transposase and inactivated derivatives
OFPHMMLE_00583 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
OFPHMMLE_00584 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
OFPHMMLE_00585 8.8e-192 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
OFPHMMLE_00586 3.5e-154 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
OFPHMMLE_00587 2.5e-134 emrY EGP Major facilitator Superfamily
OFPHMMLE_00588 5.2e-13 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
OFPHMMLE_00589 6.2e-118 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
OFPHMMLE_00590 5.8e-82
OFPHMMLE_00591 6.1e-73 K helix_turn_helix multiple antibiotic resistance protein
OFPHMMLE_00592 1.5e-32
OFPHMMLE_00593 8.9e-165 mdtG EGP Major facilitator Superfamily
OFPHMMLE_00594 3.3e-112 3.6.1.27 I Acid phosphatase homologues
OFPHMMLE_00595 5.7e-169 glsA 3.5.1.2 E Belongs to the glutaminase family
OFPHMMLE_00596 3.7e-260 P Sodium:sulfate symporter transmembrane region
OFPHMMLE_00597 7.4e-115 1.3.5.4 C FMN_bind
OFPHMMLE_00598 2.3e-224 pbuG S permease
OFPHMMLE_00599 0.0 pepO 3.4.24.71 O Peptidase family M13
OFPHMMLE_00600 4.4e-155 ropB K Helix-turn-helix XRE-family like proteins
OFPHMMLE_00601 0.0 copA 3.6.3.54 P P-type ATPase
OFPHMMLE_00602 1.1e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
OFPHMMLE_00603 6.3e-66 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
OFPHMMLE_00604 1.4e-77 atkY K Penicillinase repressor
OFPHMMLE_00605 5.5e-90
OFPHMMLE_00606 1.5e-132 yebC K Transcriptional regulatory protein
OFPHMMLE_00607 1.9e-82 S VanZ like family
OFPHMMLE_00608 1.9e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OFPHMMLE_00609 1.6e-108 mutF V ABC transporter, ATP-binding protein
OFPHMMLE_00610 6.4e-241 nhaC C Na H antiporter NhaC
OFPHMMLE_00611 9.6e-163 salL 2.5.1.63, 2.5.1.94 K S-adenosyl-l-methionine hydroxide adenosyltransferase
OFPHMMLE_00612 3.3e-95 S UPF0397 protein
OFPHMMLE_00613 0.0 ykoD P ABC transporter, ATP-binding protein
OFPHMMLE_00614 3.1e-142 cbiQ P cobalt transport
OFPHMMLE_00615 3.4e-219 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OFPHMMLE_00616 4.4e-169 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
OFPHMMLE_00617 9.5e-102 M NlpC P60 family protein
OFPHMMLE_00618 1.6e-185 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
OFPHMMLE_00619 4.1e-42 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OFPHMMLE_00621 2.6e-183 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
OFPHMMLE_00622 1.1e-123 manY G PTS system
OFPHMMLE_00623 5.6e-172 manN G system, mannose fructose sorbose family IID component
OFPHMMLE_00624 1.8e-65 manO S Domain of unknown function (DUF956)
OFPHMMLE_00625 1.3e-249 yifK E Amino acid permease
OFPHMMLE_00626 9e-219 yifK E Amino acid permease
OFPHMMLE_00627 9.1e-144 ptp2 3.1.3.48 T Tyrosine phosphatase family
OFPHMMLE_00628 4.4e-43 3.1.3.48 T Tyrosine phosphatase family
OFPHMMLE_00629 2e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
OFPHMMLE_00630 4.1e-95 cvpA S Colicin V production protein
OFPHMMLE_00631 4.4e-124 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
OFPHMMLE_00632 1.4e-140 noc K Belongs to the ParB family
OFPHMMLE_00633 3.3e-138 soj D Sporulation initiation inhibitor
OFPHMMLE_00634 2.2e-154 spo0J K Belongs to the ParB family
OFPHMMLE_00635 1.1e-42 yyzM S Bacterial protein of unknown function (DUF951)
OFPHMMLE_00636 4.6e-202 malK P ATPases associated with a variety of cellular activities
OFPHMMLE_00637 2.8e-157 gtsB P ABC-type sugar transport systems, permease components
OFPHMMLE_00638 5e-148 gtsC P Binding-protein-dependent transport system inner membrane component
OFPHMMLE_00639 7.9e-257 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
OFPHMMLE_00640 3e-240 G Bacterial extracellular solute-binding protein
OFPHMMLE_00641 8.7e-52 ypaA S Protein of unknown function (DUF1304)
OFPHMMLE_00642 8.4e-10 D nuclear chromosome segregation
OFPHMMLE_00643 4.3e-09 D nuclear chromosome segregation
OFPHMMLE_00644 6.2e-196 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OFPHMMLE_00645 2.4e-98 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
OFPHMMLE_00646 1.5e-132 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
OFPHMMLE_00647 3.7e-88 folT S ECF transporter, substrate-specific component
OFPHMMLE_00648 2.1e-143 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OFPHMMLE_00649 1.3e-38
OFPHMMLE_00650 1.4e-267 gatC G PTS system sugar-specific permease component
OFPHMMLE_00651 6.3e-51 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
OFPHMMLE_00652 7.9e-85 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
OFPHMMLE_00653 1.6e-128 S Domain of unknown function (DUF4867)
OFPHMMLE_00654 1.9e-106 rpiB 2.1.1.222, 2.1.1.64, 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
OFPHMMLE_00655 9.4e-74 lacA 5.3.1.26 G Ribose/Galactose Isomerase
OFPHMMLE_00656 1.6e-137 lacR K DeoR C terminal sensor domain
OFPHMMLE_00657 5.4e-147 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OFPHMMLE_00658 5.8e-183 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
OFPHMMLE_00659 2.6e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
OFPHMMLE_00660 1.1e-192 oppD P Belongs to the ABC transporter superfamily
OFPHMMLE_00661 4.4e-180 oppF P Belongs to the ABC transporter superfamily
OFPHMMLE_00662 7.5e-180 oppB P ABC transporter permease
OFPHMMLE_00663 0.0 UW LPXTG-motif cell wall anchor domain protein
OFPHMMLE_00664 0.0 UW LPXTG-motif cell wall anchor domain protein
OFPHMMLE_00665 4.2e-228 yttB EGP Major facilitator Superfamily
OFPHMMLE_00666 6.6e-187 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
OFPHMMLE_00667 1.1e-68 glnQ 3.6.3.21 E ABC transporter
OFPHMMLE_00668 5e-142 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
OFPHMMLE_00669 2.5e-35
OFPHMMLE_00670 3.8e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OFPHMMLE_00671 4.1e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OFPHMMLE_00672 2.6e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
OFPHMMLE_00673 6e-174 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
OFPHMMLE_00674 7.5e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
OFPHMMLE_00675 1e-181 htrA 3.4.21.107 O serine protease
OFPHMMLE_00676 3.3e-149 vicX 3.1.26.11 S domain protein
OFPHMMLE_00677 1.4e-142 yycI S YycH protein
OFPHMMLE_00678 3.5e-252 yycH S YycH protein
OFPHMMLE_00679 9.5e-281 vicK 2.7.13.3 T Histidine kinase
OFPHMMLE_00680 8.8e-101 4.2.1.6, 5.1.2.2 M Mandelate racemase muconate lactonizing enzyme
OFPHMMLE_00681 4.8e-159 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
OFPHMMLE_00682 2.3e-187 cggR K Putative sugar-binding domain
OFPHMMLE_00683 1.6e-188 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
OFPHMMLE_00684 6e-227 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
OFPHMMLE_00685 1.9e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
OFPHMMLE_00686 1.2e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
OFPHMMLE_00687 2.5e-28 secG U Preprotein translocase
OFPHMMLE_00688 9.1e-12 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
OFPHMMLE_00689 1.8e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
OFPHMMLE_00690 6.6e-22 N HicA toxin of bacterial toxin-antitoxin,
OFPHMMLE_00691 2.3e-48 S HicB_like antitoxin of bacterial toxin-antitoxin system
OFPHMMLE_00693 6.2e-80 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
OFPHMMLE_00694 0.0 helD 3.6.4.12 L DNA helicase
OFPHMMLE_00695 2.9e-120 S cog cog1373
OFPHMMLE_00696 1.3e-128 smc D Required for chromosome condensation and partitioning
OFPHMMLE_00697 0.0 kup P Transport of potassium into the cell
OFPHMMLE_00698 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
OFPHMMLE_00699 0.0 S Bacterial membrane protein, YfhO
OFPHMMLE_00700 1.9e-13 corA P CorA-like Mg2+ transporter protein
OFPHMMLE_00703 1e-90 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
OFPHMMLE_00704 2.4e-133 ecsA V ABC transporter, ATP-binding protein
OFPHMMLE_00705 1.4e-20 ltrA S Bacterial low temperature requirement A protein (LtrA)
OFPHMMLE_00706 1.9e-112 2.7.6.5 T Region found in RelA / SpoT proteins
OFPHMMLE_00707 5.3e-116 K response regulator
OFPHMMLE_00708 1.6e-233 sptS 2.7.13.3 T Histidine kinase
OFPHMMLE_00709 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
OFPHMMLE_00710 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
OFPHMMLE_00711 3.6e-27 pncA Q Isochorismatase family
OFPHMMLE_00712 3.3e-92 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
OFPHMMLE_00713 2.3e-311 carB 6.3.5.5 F Carbamoyl-phosphate synthase
OFPHMMLE_00714 4.2e-77 fld C Flavodoxin
OFPHMMLE_00715 1.2e-88 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
OFPHMMLE_00716 8.6e-130 cobQ S glutamine amidotransferase
OFPHMMLE_00717 4.9e-249 yfnA E Amino Acid
OFPHMMLE_00718 5.9e-163 EG EamA-like transporter family
OFPHMMLE_00719 4e-192 asnA 6.3.1.1 F aspartate--ammonia ligase
OFPHMMLE_00720 3.8e-82 S CAAX protease self-immunity
OFPHMMLE_00721 2.7e-296 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
OFPHMMLE_00722 8.9e-192 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OFPHMMLE_00723 4.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OFPHMMLE_00724 5.3e-228 L Transposase
OFPHMMLE_00725 5e-60
OFPHMMLE_00726 5.3e-177 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
OFPHMMLE_00727 4.8e-173 fpaP 3.4.11.5 I Releases the N-terminal proline from various substrates
OFPHMMLE_00728 7.1e-195 tcsA S ABC transporter substrate-binding protein PnrA-like
OFPHMMLE_00729 1.2e-166 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
OFPHMMLE_00730 2.3e-122 K Helix-turn-helix domain, rpiR family
OFPHMMLE_00731 3.8e-82 rarA L MgsA AAA+ ATPase C terminal
OFPHMMLE_00732 6.1e-241 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OFPHMMLE_00733 3.4e-103 E GDSL-like Lipase/Acylhydrolase
OFPHMMLE_00734 5.3e-161 coaA 2.7.1.33 F Pantothenic acid kinase
OFPHMMLE_00735 3.7e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OFPHMMLE_00736 7.9e-305 fhaB M Rib/alpha-like repeat
OFPHMMLE_00737 1.5e-212 fhaB M Rib/alpha-like repeat
OFPHMMLE_00738 5.1e-229 fhaB M Rib/alpha-like repeat
OFPHMMLE_00739 1.6e-132 licT K CAT RNA binding domain
OFPHMMLE_00740 4e-282 bglP 2.7.1.211 G phosphotransferase system
OFPHMMLE_00741 5.4e-56 bglP 2.7.1.211 G phosphotransferase system
OFPHMMLE_00742 1e-268 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
OFPHMMLE_00743 4.8e-76 rplI J Binds to the 23S rRNA
OFPHMMLE_00744 1.1e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
OFPHMMLE_00745 2.2e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
OFPHMMLE_00746 4.4e-219 I Protein of unknown function (DUF2974)
OFPHMMLE_00747 0.0 pepF E oligoendopeptidase F
OFPHMMLE_00748 2e-70 3.6.4.12 S PD-(D/E)XK nuclease family transposase
OFPHMMLE_00749 1.3e-236 lctP C L-lactate permease
OFPHMMLE_00750 6.5e-18 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
OFPHMMLE_00751 8.2e-204 gatC G PTS system sugar-specific permease component
OFPHMMLE_00752 1.2e-24 2.7.1.200, 2.7.1.202 G phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2
OFPHMMLE_00753 1.9e-135 L Transposase and inactivated derivatives, IS30 family
OFPHMMLE_00755 7.4e-111 K helix_turn_helix, mercury resistance
OFPHMMLE_00756 2.3e-232 pbuG S permease
OFPHMMLE_00757 3.4e-46 I bis(5'-adenosyl)-triphosphatase activity
OFPHMMLE_00758 1.1e-226 pbuG S permease
OFPHMMLE_00759 3.7e-168 malF P Binding-protein-dependent transport system inner membrane component
OFPHMMLE_00760 9.7e-155 malG P ABC transporter permease
OFPHMMLE_00761 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
OFPHMMLE_00762 3.3e-266 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
OFPHMMLE_00763 5.1e-63 mdlA V ABC transporter
OFPHMMLE_00764 6.1e-300 mdlB V ABC transporter
OFPHMMLE_00765 8.6e-201 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
OFPHMMLE_00766 9.8e-117 plsC 2.3.1.51 I Acyltransferase
OFPHMMLE_00767 3e-195 yabB 2.1.1.223 L Methyltransferase small domain
OFPHMMLE_00768 4e-126 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OFPHMMLE_00769 5.9e-52 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OFPHMMLE_00770 6.2e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OFPHMMLE_00771 2.4e-26 S Protein of unknown function (DUF2508)
OFPHMMLE_00772 3.7e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OFPHMMLE_00773 4.5e-52 yaaQ S Cyclic-di-AMP receptor
OFPHMMLE_00774 2.8e-154 holB 2.7.7.7 L DNA polymerase III
OFPHMMLE_00775 1.3e-57 yabA L Involved in initiation control of chromosome replication
OFPHMMLE_00776 1.8e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OFPHMMLE_00777 0.0 L Helicase C-terminal domain protein
OFPHMMLE_00778 5.7e-160 xth 3.1.11.2 L exodeoxyribonuclease III
OFPHMMLE_00779 2.5e-40 S Transglycosylase associated protein
OFPHMMLE_00781 1.6e-123 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
OFPHMMLE_00782 0.0 oppA E ABC transporter substrate-binding protein
OFPHMMLE_00783 1.1e-241 oppA E ABC transporter substrate-binding protein
OFPHMMLE_00784 1.1e-130 K response regulator
OFPHMMLE_00785 2.9e-96 yceD S Uncharacterized ACR, COG1399
OFPHMMLE_00786 1.1e-217 ylbM S Belongs to the UPF0348 family
OFPHMMLE_00787 8.2e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
OFPHMMLE_00788 1.7e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
OFPHMMLE_00789 4.4e-120 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OFPHMMLE_00790 1.6e-134 yqeH S Ribosome biogenesis GTPase YqeH
OFPHMMLE_00791 0.0 S peptidoglycan catabolic process
OFPHMMLE_00792 5.5e-122 S Phage tail protein
OFPHMMLE_00793 3.9e-213 S Phage minor structural protein
OFPHMMLE_00794 1.2e-60 S N-acetylmuramoyl-L-alanine amidase activity
OFPHMMLE_00797 8.1e-08
OFPHMMLE_00800 2.1e-97 M lysozyme activity
OFPHMMLE_00802 3e-08
OFPHMMLE_00803 1.8e-159 natA S ABC transporter, ATP-binding protein
OFPHMMLE_00804 9.7e-143 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
OFPHMMLE_00805 1.1e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OFPHMMLE_00806 8.7e-93 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
OFPHMMLE_00807 1.2e-97 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
OFPHMMLE_00808 1.5e-217 rpsA 1.17.7.4 J Ribosomal protein S1
OFPHMMLE_00809 9.4e-242 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
OFPHMMLE_00810 2e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
OFPHMMLE_00811 2.1e-28 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
OFPHMMLE_00812 2.4e-181 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
OFPHMMLE_00813 3.1e-242 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
OFPHMMLE_00814 1.1e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
OFPHMMLE_00815 9.9e-33
OFPHMMLE_00816 5.3e-144 xth 3.1.11.2 L exodeoxyribonuclease III
OFPHMMLE_00817 0.0 ptsG 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
OFPHMMLE_00818 2.4e-127 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
OFPHMMLE_00819 2.1e-138 rpiR1 K Helix-turn-helix domain, rpiR family
OFPHMMLE_00820 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
OFPHMMLE_00821 5.3e-138 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
OFPHMMLE_00822 6.4e-105 S Iron-sulfur cluster assembly protein
OFPHMMLE_00823 1.4e-228 XK27_04775 S PAS domain
OFPHMMLE_00824 2.5e-134 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
OFPHMMLE_00825 2.2e-125 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
OFPHMMLE_00826 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
OFPHMMLE_00827 3.3e-185 yfdV S Membrane transport protein
OFPHMMLE_00828 8.8e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OFPHMMLE_00829 7.9e-61 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OFPHMMLE_00830 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OFPHMMLE_00831 3.5e-117 arbZ I Phosphate acyltransferases
OFPHMMLE_00832 4.6e-236 yhjX_2 P Major Facilitator Superfamily
OFPHMMLE_00833 1.7e-249 yhjX_2 P Major Facilitator Superfamily
OFPHMMLE_00834 2.4e-186 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
OFPHMMLE_00835 2.2e-42 S Peptidase propeptide and YPEB domain
OFPHMMLE_00836 6.9e-76 S LexA-binding, inner membrane-associated putative hydrolase
OFPHMMLE_00837 4.5e-98 K LysR substrate binding domain
OFPHMMLE_00838 4.2e-177 lacX 5.1.3.3 G Aldose 1-epimerase
OFPHMMLE_00839 8.2e-252 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OFPHMMLE_00840 9.7e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OFPHMMLE_00841 2e-169 xerC D Phage integrase, N-terminal SAM-like domain
OFPHMMLE_00842 2.7e-244 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
OFPHMMLE_00843 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OFPHMMLE_00844 2.6e-152 dprA LU DNA protecting protein DprA
OFPHMMLE_00845 9.8e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OFPHMMLE_00846 3.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OFPHMMLE_00847 1.1e-264 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
OFPHMMLE_00848 2e-35 yozE S Belongs to the UPF0346 family
OFPHMMLE_00849 3.1e-122 DegV S Uncharacterised protein, DegV family COG1307
OFPHMMLE_00850 2.2e-143 2.4.1.293 GT2 M Glycosyltransferase like family 2
OFPHMMLE_00851 6.9e-124 S Alpha/beta hydrolase family
OFPHMMLE_00852 1.4e-62
OFPHMMLE_00853 4.1e-181 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OFPHMMLE_00854 1.3e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OFPHMMLE_00855 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OFPHMMLE_00856 1.4e-189 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
OFPHMMLE_00857 2.1e-99 S Protein of unknown function (DUF3990)
OFPHMMLE_00858 1.3e-47
OFPHMMLE_00859 9.7e-169 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OFPHMMLE_00860 1.1e-261 glnA 6.3.1.2 E glutamine synthetase
OFPHMMLE_00861 1.1e-204 EGP Major facilitator Superfamily
OFPHMMLE_00862 4.3e-152 S haloacid dehalogenase-like hydrolase
OFPHMMLE_00863 6.5e-173 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
OFPHMMLE_00864 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
OFPHMMLE_00865 6.1e-171 dacA 3.4.16.4 M Belongs to the peptidase S11 family
OFPHMMLE_00866 1.4e-98 M ErfK YbiS YcfS YnhG
OFPHMMLE_00867 5.6e-228 G Major Facilitator Superfamily
OFPHMMLE_00868 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OFPHMMLE_00869 3.3e-211 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
OFPHMMLE_00870 8.1e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
OFPHMMLE_00871 3.9e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
OFPHMMLE_00872 2.6e-67 3.1.31.1 M domain protein
OFPHMMLE_00873 0.0 infB UW LPXTG-motif cell wall anchor domain protein
OFPHMMLE_00874 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OFPHMMLE_00875 4.7e-82 rimP J Required for maturation of 30S ribosomal subunits
OFPHMMLE_00876 1.1e-217 nusA K Participates in both transcription termination and antitermination
OFPHMMLE_00877 2e-46 ylxR K Protein of unknown function (DUF448)
OFPHMMLE_00878 2e-35 agaS G SIS domain
OFPHMMLE_00879 1.8e-228 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
OFPHMMLE_00880 8.7e-84 2.7.1.191 G PTS system sorbose subfamily IIB component
OFPHMMLE_00881 1.9e-140 XK27_08455 G PTS system sorbose-specific iic component
OFPHMMLE_00882 5.5e-147 manZ_1 G PTS system mannose/fructose/sorbose family IID component
OFPHMMLE_00883 4.6e-67 2.7.1.191 G PTS system fructose IIA component
OFPHMMLE_00884 1.2e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
OFPHMMLE_00885 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
OFPHMMLE_00886 3.1e-73
OFPHMMLE_00887 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OFPHMMLE_00888 2e-32 cspA K 'Cold-shock' DNA-binding domain
OFPHMMLE_00889 9.7e-103 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
OFPHMMLE_00891 1.6e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OFPHMMLE_00892 1.9e-56 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
OFPHMMLE_00893 1.2e-152 lacT K PRD domain
OFPHMMLE_00894 1.2e-140 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OFPHMMLE_00895 1.7e-78 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
OFPHMMLE_00896 3.4e-274 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
OFPHMMLE_00897 1.2e-52 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
OFPHMMLE_00898 2.7e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
OFPHMMLE_00899 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OFPHMMLE_00900 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
OFPHMMLE_00901 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OFPHMMLE_00902 2.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OFPHMMLE_00903 1.3e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OFPHMMLE_00904 1.3e-61 rplQ J Ribosomal protein L17
OFPHMMLE_00905 1.7e-282 S C4-dicarboxylate anaerobic carrier
OFPHMMLE_00906 5.8e-85 dps P Belongs to the Dps family
OFPHMMLE_00908 3.2e-164 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OFPHMMLE_00909 4.8e-128 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
OFPHMMLE_00910 7.3e-236 XK27_08315 M Sulfatase
OFPHMMLE_00911 6.3e-243 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OFPHMMLE_00913 3.7e-262 pepC 3.4.22.40 E aminopeptidase
OFPHMMLE_00914 8.8e-124 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
OFPHMMLE_00915 3.9e-256 pepC 3.4.22.40 E aminopeptidase
OFPHMMLE_00916 7.7e-43
OFPHMMLE_00917 8.8e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
OFPHMMLE_00918 9.5e-77 hsp O Belongs to the small heat shock protein (HSP20) family
OFPHMMLE_00919 3.4e-293 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OFPHMMLE_00920 9.8e-68
OFPHMMLE_00921 1.4e-248 celD 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)