ORF_ID e_value Gene_name EC_number CAZy COGs Description
OKBOLDLM_00001 2.2e-38 S COG NOG14552 non supervised orthologous group
OKBOLDLM_00002 1.5e-175 yaaC S YaaC-like Protein
OKBOLDLM_00003 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
OKBOLDLM_00004 1.2e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
OKBOLDLM_00005 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
OKBOLDLM_00006 4.7e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
OKBOLDLM_00007 2.1e-201 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OKBOLDLM_00008 2.3e-196 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
OKBOLDLM_00009 1.3e-09
OKBOLDLM_00010 6.6e-119 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
OKBOLDLM_00011 1.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
OKBOLDLM_00012 3.9e-208 yaaH M Glycoside Hydrolase Family
OKBOLDLM_00013 6.6e-96 yaaI Q COG1335 Amidases related to nicotinamidase
OKBOLDLM_00014 9.5e-83 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
OKBOLDLM_00015 2.3e-311 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OKBOLDLM_00016 1e-35 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OKBOLDLM_00017 2.3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OKBOLDLM_00018 3.6e-32 yaaL S Protein of unknown function (DUF2508)
OKBOLDLM_00019 4.8e-36 bofA S Sigma-K factor-processing regulatory protein BofA
OKBOLDLM_00020 4.2e-29 csfB S Inhibitor of sigma-G Gin
OKBOLDLM_00021 1.1e-99 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
OKBOLDLM_00022 2.6e-176 yaaN P Belongs to the TelA family
OKBOLDLM_00023 1.9e-256 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
OKBOLDLM_00024 7.8e-109 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OKBOLDLM_00025 7.5e-55 yaaQ S protein conserved in bacteria
OKBOLDLM_00026 3.8e-70 yaaR S protein conserved in bacteria
OKBOLDLM_00027 8.5e-179 holB 2.7.7.7 L DNA polymerase III
OKBOLDLM_00028 1.1e-144 yaaT S stage 0 sporulation protein
OKBOLDLM_00029 5e-36 yabA L Involved in initiation control of chromosome replication
OKBOLDLM_00030 1.6e-137 yabB 2.1.1.223 S Conserved hypothetical protein 95
OKBOLDLM_00031 5.2e-47 yazA L endonuclease containing a URI domain
OKBOLDLM_00032 2.8e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OKBOLDLM_00033 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
OKBOLDLM_00034 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OKBOLDLM_00035 2.2e-142 tatD L hydrolase, TatD
OKBOLDLM_00036 4e-216 rpfB GH23 T protein conserved in bacteria
OKBOLDLM_00037 2.3e-96 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OKBOLDLM_00038 2.4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
OKBOLDLM_00039 8.2e-125 yabG S peptidase
OKBOLDLM_00040 7.8e-39 veg S protein conserved in bacteria
OKBOLDLM_00041 2.9e-27 sspF S DNA topological change
OKBOLDLM_00042 7.8e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OKBOLDLM_00043 2.9e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
OKBOLDLM_00044 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
OKBOLDLM_00045 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
OKBOLDLM_00046 1.7e-246 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OKBOLDLM_00047 2.7e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OKBOLDLM_00048 2.8e-103 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OKBOLDLM_00049 1.2e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
OKBOLDLM_00050 6.9e-39 yabK S Peptide ABC transporter permease
OKBOLDLM_00051 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OKBOLDLM_00052 2.6e-89 spoVT K stage V sporulation protein
OKBOLDLM_00053 5.8e-270 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OKBOLDLM_00054 7e-270 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
OKBOLDLM_00055 5.6e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
OKBOLDLM_00056 1.9e-49 yabP S Sporulation protein YabP
OKBOLDLM_00057 8.7e-100 yabQ S spore cortex biosynthesis protein
OKBOLDLM_00058 9.2e-57 divIC D Septum formation initiator
OKBOLDLM_00059 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
OKBOLDLM_00062 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
OKBOLDLM_00063 1.2e-121 yabS S protein containing a von Willebrand factor type A (vWA) domain
OKBOLDLM_00064 9.2e-181 KLT serine threonine protein kinase
OKBOLDLM_00065 2.1e-263 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
OKBOLDLM_00066 2.5e-92 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
OKBOLDLM_00067 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OKBOLDLM_00068 5.5e-138 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
OKBOLDLM_00069 1.2e-160 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OKBOLDLM_00070 5.7e-150 yacD 5.2.1.8 O peptidyl-prolyl isomerase
OKBOLDLM_00071 1.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
OKBOLDLM_00072 1.2e-263 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OKBOLDLM_00073 5.7e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
OKBOLDLM_00074 1.6e-149 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
OKBOLDLM_00075 9.1e-153 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OKBOLDLM_00076 2.6e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OKBOLDLM_00077 3e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OKBOLDLM_00078 7.1e-28 yazB K transcriptional
OKBOLDLM_00079 1e-179 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OKBOLDLM_00080 1.6e-285 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
OKBOLDLM_00081 7.5e-77 ctsR K Belongs to the CtsR family
OKBOLDLM_00082 1.1e-60 mcsA 2.7.14.1 S protein with conserved CXXC pairs
OKBOLDLM_00083 2.7e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
OKBOLDLM_00084 0.0 clpC O Belongs to the ClpA ClpB family
OKBOLDLM_00085 1.9e-253 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OKBOLDLM_00086 2.7e-194 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
OKBOLDLM_00087 5.2e-185 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
OKBOLDLM_00088 1.8e-122 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
OKBOLDLM_00089 3.5e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
OKBOLDLM_00090 4.2e-275 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OKBOLDLM_00091 1.6e-117 cysE 2.3.1.30 E Serine acetyltransferase
OKBOLDLM_00092 1.1e-267 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
OKBOLDLM_00093 1.7e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
OKBOLDLM_00094 1.8e-133 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OKBOLDLM_00095 1.8e-87 yacP S RNA-binding protein containing a PIN domain
OKBOLDLM_00096 4.4e-115 sigH K Belongs to the sigma-70 factor family
OKBOLDLM_00097 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
OKBOLDLM_00098 1.4e-95 nusG K Participates in transcription elongation, termination and antitermination
OKBOLDLM_00099 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OKBOLDLM_00100 2.1e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
OKBOLDLM_00101 1.9e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OKBOLDLM_00102 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
OKBOLDLM_00103 4.8e-108 rsmC 2.1.1.172 J Methyltransferase
OKBOLDLM_00104 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OKBOLDLM_00105 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OKBOLDLM_00106 2.7e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
OKBOLDLM_00107 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OKBOLDLM_00108 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
OKBOLDLM_00109 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OKBOLDLM_00110 1.8e-223 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OKBOLDLM_00111 2.6e-172 ybaC 3.4.11.5 S Alpha/beta hydrolase family
OKBOLDLM_00112 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
OKBOLDLM_00113 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OKBOLDLM_00114 1.5e-104 rplD J Forms part of the polypeptide exit tunnel
OKBOLDLM_00115 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
OKBOLDLM_00116 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OKBOLDLM_00117 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OKBOLDLM_00118 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OKBOLDLM_00119 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OKBOLDLM_00120 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OKBOLDLM_00121 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
OKBOLDLM_00122 1.8e-38 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OKBOLDLM_00123 8.7e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OKBOLDLM_00124 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OKBOLDLM_00125 3.9e-93 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OKBOLDLM_00126 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OKBOLDLM_00127 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OKBOLDLM_00128 1.5e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OKBOLDLM_00129 2.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OKBOLDLM_00130 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OKBOLDLM_00131 1.9e-23 rpmD J Ribosomal protein L30
OKBOLDLM_00132 4.1e-72 rplO J binds to the 23S rRNA
OKBOLDLM_00133 3.3e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
OKBOLDLM_00134 9.8e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
OKBOLDLM_00135 2.6e-140 map 3.4.11.18 E Methionine aminopeptidase
OKBOLDLM_00136 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OKBOLDLM_00137 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
OKBOLDLM_00138 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OKBOLDLM_00139 2.8e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OKBOLDLM_00140 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OKBOLDLM_00141 4.7e-58 rplQ J Ribosomal protein L17
OKBOLDLM_00142 1.4e-153 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OKBOLDLM_00143 1.2e-144 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OKBOLDLM_00144 1.9e-136 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OKBOLDLM_00145 5.9e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
OKBOLDLM_00146 7.1e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OKBOLDLM_00147 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
OKBOLDLM_00148 2.7e-140 ybaJ Q Methyltransferase domain
OKBOLDLM_00149 5.3e-15 ybaJ Q Methyltransferase domain
OKBOLDLM_00150 3.6e-76 ybaK S Protein of unknown function (DUF2521)
OKBOLDLM_00151 2.4e-130 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OKBOLDLM_00152 2.5e-192 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
OKBOLDLM_00153 1.7e-75 gerD
OKBOLDLM_00154 1.7e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
OKBOLDLM_00155 1.2e-127 pdaB 3.5.1.104 G Polysaccharide deacetylase
OKBOLDLM_00158 1.6e-08
OKBOLDLM_00161 2.2e-213 glcP G Major Facilitator Superfamily
OKBOLDLM_00162 1e-245 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OKBOLDLM_00163 2.2e-176 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
OKBOLDLM_00164 8.6e-198 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
OKBOLDLM_00165 1.1e-222 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
OKBOLDLM_00166 3.2e-170 ybaS 1.1.1.58 S Na -dependent transporter
OKBOLDLM_00167 6.4e-102 ybbA S Putative esterase
OKBOLDLM_00168 7e-176 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OKBOLDLM_00169 1.5e-175 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OKBOLDLM_00170 4.5e-169 feuA P Iron-uptake system-binding protein
OKBOLDLM_00171 1.3e-290 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
OKBOLDLM_00172 7.8e-230 ybbC 3.2.1.52 S protein conserved in bacteria
OKBOLDLM_00173 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
OKBOLDLM_00174 1.5e-236 yfeW 3.4.16.4 V Belongs to the UPF0214 family
OKBOLDLM_00175 1.9e-229 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OKBOLDLM_00176 8.3e-160 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
OKBOLDLM_00177 4.9e-59 ybbJ J acetyltransferase
OKBOLDLM_00178 1.2e-74 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
OKBOLDLM_00182 1.5e-07
OKBOLDLM_00184 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
OKBOLDLM_00185 5.2e-113 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
OKBOLDLM_00186 1.1e-144 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OKBOLDLM_00187 1.9e-216 ybbR S protein conserved in bacteria
OKBOLDLM_00188 2.3e-251 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OKBOLDLM_00189 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
OKBOLDLM_00190 9.2e-36
OKBOLDLM_00191 1.2e-198 O growth
OKBOLDLM_00192 1.1e-52 S ABC-2 family transporter protein
OKBOLDLM_00193 1.3e-98 ybdN
OKBOLDLM_00194 2.7e-131 ybdO S Domain of unknown function (DUF4885)
OKBOLDLM_00195 4.4e-160 dkgB S Aldo/keto reductase family
OKBOLDLM_00196 1.5e-92 yxaC M effector of murein hydrolase
OKBOLDLM_00197 2.2e-50 S LrgA family
OKBOLDLM_00198 2.3e-67 yxaD K helix_turn_helix multiple antibiotic resistance protein
OKBOLDLM_00199 2.7e-255 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
OKBOLDLM_00200 3.6e-94 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
OKBOLDLM_00201 4e-177 T COG4585 Signal transduction histidine kinase
OKBOLDLM_00202 3e-100 KT LuxR family transcriptional regulator
OKBOLDLM_00203 6.4e-160 V COG1131 ABC-type multidrug transport system, ATPase component
OKBOLDLM_00204 8.4e-189 V COG0842 ABC-type multidrug transport system, permease component
OKBOLDLM_00205 1.8e-180 V ABC-2 family transporter protein
OKBOLDLM_00206 9.2e-23
OKBOLDLM_00207 1.5e-75 S Domain of unknown function (DUF4879)
OKBOLDLM_00208 1.3e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
OKBOLDLM_00209 2.5e-100 yqeB
OKBOLDLM_00210 2.3e-38 ybyB
OKBOLDLM_00211 1.2e-275 ybeC E amino acid
OKBOLDLM_00212 1.2e-15 S Protein of unknown function (DUF2651)
OKBOLDLM_00213 2e-163 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
OKBOLDLM_00214 1.6e-257 glpT G -transporter
OKBOLDLM_00215 2.7e-17 S Protein of unknown function (DUF2651)
OKBOLDLM_00216 9.5e-211 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
OKBOLDLM_00218 3.9e-81 K Helix-turn-helix XRE-family like proteins
OKBOLDLM_00219 7e-187 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
OKBOLDLM_00220 1.7e-207 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
OKBOLDLM_00221 1.9e-92 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OKBOLDLM_00222 5.1e-84 ybfM S SNARE associated Golgi protein
OKBOLDLM_00223 9e-150 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
OKBOLDLM_00224 2.8e-39 ybfN
OKBOLDLM_00225 2.6e-188 yceA S Belongs to the UPF0176 family
OKBOLDLM_00226 6.3e-211 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OKBOLDLM_00227 1.9e-192 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
OKBOLDLM_00228 9.3e-237 mmuP E amino acid
OKBOLDLM_00229 7.7e-177 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
OKBOLDLM_00230 2.4e-251 agcS E Sodium alanine symporter
OKBOLDLM_00231 8.3e-72 glsA 3.5.1.2 E Belongs to the glutaminase family
OKBOLDLM_00232 2.6e-34 glsA 3.5.1.2 E Belongs to the glutaminase family
OKBOLDLM_00233 4.6e-201 phoQ 2.7.13.3 T Histidine kinase
OKBOLDLM_00234 1.7e-155 glnL T Regulator
OKBOLDLM_00235 3.5e-126 ycbJ S Macrolide 2'-phosphotransferase
OKBOLDLM_00236 4.5e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
OKBOLDLM_00237 2.1e-152 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OKBOLDLM_00238 3.5e-91 ydfN C nitroreductase
OKBOLDLM_00239 2.1e-73 ydfO E COG0346 Lactoylglutathione lyase and related lyases
OKBOLDLM_00240 5.8e-76 ydfO E COG0346 Lactoylglutathione lyase and related lyases
OKBOLDLM_00241 7.5e-62 mhqP S DoxX
OKBOLDLM_00242 3.5e-55 traF CO Thioredoxin
OKBOLDLM_00243 1.7e-11 L COG3666 Transposase and inactivated derivatives
OKBOLDLM_00244 7.4e-62 ycbP S Protein of unknown function (DUF2512)
OKBOLDLM_00245 4.8e-78 sleB 3.5.1.28 M Cell wall
OKBOLDLM_00246 2.6e-261 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
OKBOLDLM_00247 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
OKBOLDLM_00248 7.6e-122 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OKBOLDLM_00249 5e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
OKBOLDLM_00250 2.7e-189 ycbU E Selenocysteine lyase
OKBOLDLM_00251 1.4e-235 lmrB EGP the major facilitator superfamily
OKBOLDLM_00252 3.6e-97 yxaF K Transcriptional regulator
OKBOLDLM_00253 7.5e-46 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
OKBOLDLM_00254 6.4e-16 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
OKBOLDLM_00255 8e-191 yccF K DNA-templated transcriptional preinitiation complex assembly
OKBOLDLM_00256 1e-165 yccK C Aldo keto reductase
OKBOLDLM_00257 2.7e-164 ycdA S Domain of unknown function (DUF5105)
OKBOLDLM_00258 1.5e-24 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
OKBOLDLM_00259 3.4e-195 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
OKBOLDLM_00260 3e-251 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
OKBOLDLM_00261 1.6e-88 cwlK M D-alanyl-D-alanine carboxypeptidase
OKBOLDLM_00262 2e-171 S response regulator aspartate phosphatase
OKBOLDLM_00263 2e-135 IQ Enoyl-(Acyl carrier protein) reductase
OKBOLDLM_00264 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
OKBOLDLM_00265 1.6e-48 S Domain of unknown function (DUF4188)
OKBOLDLM_00266 1.5e-47 padR K Virulence activator alpha C-term
OKBOLDLM_00267 1.1e-162 adcA P Belongs to the bacterial solute-binding protein 9 family
OKBOLDLM_00268 1.6e-131 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
OKBOLDLM_00269 2.2e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
OKBOLDLM_00270 1.4e-181 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OKBOLDLM_00271 6.2e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
OKBOLDLM_00272 6.3e-105 yceD T proteins involved in stress response, homologs of TerZ and
OKBOLDLM_00273 3.3e-106 yceE T proteins involved in stress response, homologs of TerZ and
OKBOLDLM_00274 1.7e-137 terC P Protein of unknown function (DUF475)
OKBOLDLM_00275 2.7e-307 yceG S Putative component of 'biosynthetic module'
OKBOLDLM_00276 4.3e-192 yceH P Belongs to the TelA family
OKBOLDLM_00277 1.8e-207 naiP P Uncharacterised MFS-type transporter YbfB
OKBOLDLM_00279 1.4e-226 proV 3.6.3.32 E glycine betaine
OKBOLDLM_00280 6.9e-137 opuAB P glycine betaine
OKBOLDLM_00281 4.2e-161 opuAC E glycine betaine
OKBOLDLM_00282 1e-204 amhX S amidohydrolase
OKBOLDLM_00283 7.4e-188 ycgA S Membrane
OKBOLDLM_00284 1.3e-24 ycgA S Membrane
OKBOLDLM_00285 5.2e-42 ycgB
OKBOLDLM_00286 2.3e-12 S RDD family
OKBOLDLM_00287 2.6e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
OKBOLDLM_00288 2.9e-42 mdr EGP Major facilitator Superfamily
OKBOLDLM_00289 1.2e-198 mdr EGP Major facilitator Superfamily
OKBOLDLM_00290 2.9e-73 emrR K helix_turn_helix multiple antibiotic resistance protein
OKBOLDLM_00292 4.5e-42 ycgF E Lysine exporter protein LysE YggA
OKBOLDLM_00293 1.5e-58 ycgF E Lysine exporter protein LysE YggA
OKBOLDLM_00294 3.1e-144 yqcI S YqcI/YcgG family
OKBOLDLM_00295 4.5e-239 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
OKBOLDLM_00296 4.2e-112 ycgI S Domain of unknown function (DUF1989)
OKBOLDLM_00297 3.2e-147 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
OKBOLDLM_00298 3.8e-129 4.2.1.118 G Xylose isomerase-like TIM barrel
OKBOLDLM_00299 4.1e-221 G COG0477 Permeases of the major facilitator superfamily
OKBOLDLM_00300 3.3e-103 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OKBOLDLM_00301 4e-181 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
OKBOLDLM_00302 7.6e-138 ycgL S Predicted nucleotidyltransferase
OKBOLDLM_00303 6.2e-168 ycgM E Proline dehydrogenase
OKBOLDLM_00304 2.9e-290 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
OKBOLDLM_00305 3.2e-243 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OKBOLDLM_00306 3.7e-224 ycgP QT COG2508 Regulator of polyketide synthase expression
OKBOLDLM_00307 2.4e-184 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
OKBOLDLM_00308 9e-262 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
OKBOLDLM_00309 1.5e-55 nirD 1.7.1.15 P Nitrite reductase
OKBOLDLM_00310 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OKBOLDLM_00311 2.7e-39 nasA P COG2223 Nitrate nitrite transporter
OKBOLDLM_00312 3.4e-222 yciC S GTPases (G3E family)
OKBOLDLM_00313 6.1e-174 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
OKBOLDLM_00314 5.2e-72 yckC S membrane
OKBOLDLM_00315 3.5e-49 S Protein of unknown function (DUF2680)
OKBOLDLM_00316 2.3e-286 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OKBOLDLM_00317 9.7e-65 nin S Competence protein J (ComJ)
OKBOLDLM_00318 4.2e-77 nucA M Deoxyribonuclease NucA/NucB
OKBOLDLM_00319 1.3e-91 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
OKBOLDLM_00320 1.2e-101 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
OKBOLDLM_00321 1.1e-62 hxlR K transcriptional
OKBOLDLM_00322 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OKBOLDLM_00323 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OKBOLDLM_00324 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
OKBOLDLM_00325 2.7e-137 srfAD Q thioesterase
OKBOLDLM_00326 8.8e-248 bamJ E Aminotransferase class I and II
OKBOLDLM_00327 5.5e-121 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
OKBOLDLM_00328 8e-106 yczE S membrane
OKBOLDLM_00329 1.7e-131 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OKBOLDLM_00330 1e-117 tcyB P COG0765 ABC-type amino acid transport system, permease component
OKBOLDLM_00331 4.4e-138 tcyA ET Belongs to the bacterial solute-binding protein 3 family
OKBOLDLM_00332 1.6e-152 bsdA K LysR substrate binding domain
OKBOLDLM_00333 3.5e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
OKBOLDLM_00334 1.5e-280 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
OKBOLDLM_00335 9.2e-36 bsdD 4.1.1.61 S response to toxic substance
OKBOLDLM_00336 6.6e-73 yclD
OKBOLDLM_00337 6.8e-265 dtpT E amino acid peptide transporter
OKBOLDLM_00338 1.5e-263 yclG M Pectate lyase superfamily protein
OKBOLDLM_00340 1.7e-280 gerKA EG Spore germination protein
OKBOLDLM_00341 5.5e-228 gerKC S spore germination
OKBOLDLM_00342 1.9e-190 gerKB F Spore germination protein
OKBOLDLM_00343 3e-248 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OKBOLDLM_00344 2.2e-90 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OKBOLDLM_00345 3.4e-138 yxeM M Belongs to the bacterial solute-binding protein 3 family
OKBOLDLM_00346 1.7e-114 yxeN P COG0765 ABC-type amino acid transport system, permease component
OKBOLDLM_00347 5.9e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
OKBOLDLM_00348 1.6e-213 yxeP 3.5.1.47 E hydrolase activity
OKBOLDLM_00349 4.1e-240 yxeQ S MmgE/PrpD family
OKBOLDLM_00350 1.8e-119 yclH P ABC transporter
OKBOLDLM_00351 1.1e-222 yclI V ABC transporter (permease) YclI
OKBOLDLM_00352 9.9e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OKBOLDLM_00353 9.5e-256 T PhoQ Sensor
OKBOLDLM_00354 2.7e-75 S aspartate phosphatase
OKBOLDLM_00357 2.7e-247 lysC 2.7.2.4 E Belongs to the aspartokinase family
OKBOLDLM_00358 6.3e-163 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OKBOLDLM_00359 2.3e-165 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OKBOLDLM_00360 5.8e-135 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
OKBOLDLM_00361 7.4e-172 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
OKBOLDLM_00362 1.8e-246 ycnB EGP Major facilitator Superfamily
OKBOLDLM_00363 1.1e-148 ycnC K Transcriptional regulator
OKBOLDLM_00364 1.4e-133 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
OKBOLDLM_00365 1.4e-44 ycnE S Monooxygenase
OKBOLDLM_00366 1.2e-49 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
OKBOLDLM_00367 4.7e-255 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OKBOLDLM_00368 1.1e-210 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OKBOLDLM_00369 3.3e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OKBOLDLM_00370 2.6e-147 glcU U Glucose uptake
OKBOLDLM_00371 3.3e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OKBOLDLM_00372 6.2e-95 ycnI S protein conserved in bacteria
OKBOLDLM_00373 2.4e-287 ycnJ P protein, homolog of Cu resistance protein CopC
OKBOLDLM_00374 8.4e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
OKBOLDLM_00375 4.3e-53
OKBOLDLM_00376 2.1e-231 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
OKBOLDLM_00377 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
OKBOLDLM_00378 1.8e-201 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
OKBOLDLM_00379 2.7e-59 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
OKBOLDLM_00381 2.6e-135 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
OKBOLDLM_00382 1e-131 ycsF S Belongs to the UPF0271 (lamB) family
OKBOLDLM_00383 4.5e-206 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
OKBOLDLM_00384 5.1e-142 ycsI S Belongs to the D-glutamate cyclase family
OKBOLDLM_00385 3.1e-133 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
OKBOLDLM_00386 5.1e-179 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
OKBOLDLM_00387 1.5e-125 kipR K Transcriptional regulator
OKBOLDLM_00388 2e-112 ycsK E anatomical structure formation involved in morphogenesis
OKBOLDLM_00390 5.2e-53 yczJ S biosynthesis
OKBOLDLM_00391 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
OKBOLDLM_00392 1.1e-167 ydhF S Oxidoreductase
OKBOLDLM_00393 0.0 mtlR K transcriptional regulator, MtlR
OKBOLDLM_00394 9.7e-283 ydaB IQ acyl-CoA ligase
OKBOLDLM_00395 8.3e-154 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OKBOLDLM_00396 9.6e-94 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
OKBOLDLM_00397 3e-113 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
OKBOLDLM_00398 3.4e-76 ydaG 1.4.3.5 S general stress protein
OKBOLDLM_00399 1.2e-135 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
OKBOLDLM_00400 3.9e-47 ydzA EGP Major facilitator Superfamily
OKBOLDLM_00401 4.3e-74 lrpC K Transcriptional regulator
OKBOLDLM_00402 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OKBOLDLM_00403 2.9e-188 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
OKBOLDLM_00404 6.5e-143 ydaK T Diguanylate cyclase, GGDEF domain
OKBOLDLM_00405 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
OKBOLDLM_00406 1e-229 ydaM M Glycosyl transferase family group 2
OKBOLDLM_00407 0.0 ydaN S Bacterial cellulose synthase subunit
OKBOLDLM_00408 0.0 ydaO E amino acid
OKBOLDLM_00409 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
OKBOLDLM_00410 7.1e-61 K acetyltransferase
OKBOLDLM_00411 2.8e-87 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
OKBOLDLM_00412 4.8e-69
OKBOLDLM_00413 2e-183 S Histidine kinase
OKBOLDLM_00416 4.7e-39
OKBOLDLM_00417 1.9e-223 mntH P H( )-stimulated, divalent metal cation uptake system
OKBOLDLM_00420 5.5e-33 ydaT
OKBOLDLM_00421 5.8e-73 yvaD S Family of unknown function (DUF5360)
OKBOLDLM_00422 1.1e-48 yvaE P Small Multidrug Resistance protein
OKBOLDLM_00423 1.2e-135 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
OKBOLDLM_00425 7e-56 ydbB G Cupin domain
OKBOLDLM_00426 5.1e-57 ydbC S Domain of unknown function (DUF4937
OKBOLDLM_00427 2.5e-152 ydbD P Catalase
OKBOLDLM_00428 1.4e-41 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
OKBOLDLM_00429 3.6e-135 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
OKBOLDLM_00430 1.3e-293 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
OKBOLDLM_00431 1.1e-113 dctR T COG4565 Response regulator of citrate malate metabolism
OKBOLDLM_00432 2.7e-222 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OKBOLDLM_00433 2.2e-156 ydbI S AI-2E family transporter
OKBOLDLM_00434 5.7e-169 ydbJ V ABC transporter, ATP-binding protein
OKBOLDLM_00435 7.7e-127 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
OKBOLDLM_00436 4.6e-52 ydbL
OKBOLDLM_00437 2.7e-200 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
OKBOLDLM_00438 3.5e-12 S Fur-regulated basic protein B
OKBOLDLM_00439 9.2e-10 S Fur-regulated basic protein A
OKBOLDLM_00440 4.4e-118 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OKBOLDLM_00441 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
OKBOLDLM_00442 1.3e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
OKBOLDLM_00443 3.7e-249 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
OKBOLDLM_00444 1.8e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
OKBOLDLM_00445 4.6e-61 ydbS S Bacterial PH domain
OKBOLDLM_00446 6.6e-252 ydbT S Membrane
OKBOLDLM_00447 5.8e-106 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
OKBOLDLM_00448 5.4e-54 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
OKBOLDLM_00449 1.3e-179 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
OKBOLDLM_00450 3.9e-215 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OKBOLDLM_00451 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
OKBOLDLM_00452 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
OKBOLDLM_00453 3e-137 rsbR T Positive regulator of sigma-B
OKBOLDLM_00454 1.8e-57 rsbS T antagonist
OKBOLDLM_00455 4.2e-68 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
OKBOLDLM_00456 1.8e-184 rsbU 3.1.3.3 KT phosphatase
OKBOLDLM_00457 2.7e-52 rsbV T Belongs to the anti-sigma-factor antagonist family
OKBOLDLM_00458 6.6e-84 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
OKBOLDLM_00459 2e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OKBOLDLM_00460 2.5e-104 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
OKBOLDLM_00461 0.0 yhgF K COG2183 Transcriptional accessory protein
OKBOLDLM_00462 1.7e-14
OKBOLDLM_00463 1.4e-56 ydcK S Belongs to the SprT family
OKBOLDLM_00471 3.7e-139 I esterase
OKBOLDLM_00472 1.5e-47 ohrB O OsmC-like protein
OKBOLDLM_00473 2.8e-49 ohrR K Transcriptional regulator
OKBOLDLM_00474 2.8e-13 S Domain of unknown function (DUF4367)
OKBOLDLM_00475 4.9e-54
OKBOLDLM_00476 8.2e-77 K Transcriptional regulator
OKBOLDLM_00477 2.3e-95 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OKBOLDLM_00478 5.1e-30 cspL K Cold shock
OKBOLDLM_00479 8.9e-111 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
OKBOLDLM_00480 3.1e-101 S Protein of unknown function (DUF2812)
OKBOLDLM_00481 1.6e-49 K Transcriptional regulator PadR-like family
OKBOLDLM_00482 7.4e-237 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OKBOLDLM_00483 5.9e-188 ydeG EGP Major facilitator superfamily
OKBOLDLM_00484 1.1e-50 S Patatin-like phospholipase
OKBOLDLM_00485 7e-45 S Patatin-like phospholipase
OKBOLDLM_00487 1.8e-102 ygaK C COG0277 FAD FMN-containing dehydrogenases
OKBOLDLM_00488 1.8e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OKBOLDLM_00489 2.7e-150 czcD P COG1230 Co Zn Cd efflux system component
OKBOLDLM_00490 1.4e-160 S SNARE associated Golgi protein
OKBOLDLM_00491 5.8e-97 yrkC G Cupin domain
OKBOLDLM_00492 1.8e-82 yyaR K Acetyltransferase (GNAT) domain
OKBOLDLM_00493 6.6e-146 ydeE K AraC family transcriptional regulator
OKBOLDLM_00495 2.6e-186 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
OKBOLDLM_00496 7.1e-47 ydeH
OKBOLDLM_00497 1.3e-160 S Sodium Bile acid symporter family
OKBOLDLM_00498 5.1e-198 adhA 1.1.1.1 C alcohol dehydrogenase
OKBOLDLM_00499 5e-61 yraB K helix_turn_helix, mercury resistance
OKBOLDLM_00500 1.4e-218 mleN_2 C antiporter
OKBOLDLM_00501 4.6e-247 K helix_turn_helix gluconate operon transcriptional repressor
OKBOLDLM_00502 2.6e-101 paiB K Transcriptional regulator
OKBOLDLM_00503 7.4e-169 ydeR EGP Major facilitator Superfamily
OKBOLDLM_00504 1.8e-99 ydeS K Transcriptional regulator
OKBOLDLM_00505 5.7e-150 ydeK EG -transporter
OKBOLDLM_00506 9e-251 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OKBOLDLM_00507 2.6e-46 yraD M Spore coat protein
OKBOLDLM_00508 3.1e-24 yraE
OKBOLDLM_00509 3.7e-218 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
OKBOLDLM_00510 8.4e-63 yraF M Spore coat protein
OKBOLDLM_00511 8.4e-35 yraG
OKBOLDLM_00512 2.3e-35 ydfJ S drug exporters of the RND superfamily
OKBOLDLM_00513 1.2e-126 puuD S Peptidase C26
OKBOLDLM_00514 2.6e-289 expZ S ABC transporter
OKBOLDLM_00515 2.6e-89 ynaD J Acetyltransferase (GNAT) domain
OKBOLDLM_00516 7.4e-62 S Uncharacterized protein conserved in bacteria (DUF2179)
OKBOLDLM_00517 7.2e-75 S Uncharacterized protein conserved in bacteria (DUF2179)
OKBOLDLM_00518 2.5e-195 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
OKBOLDLM_00519 2e-206 tcaB EGP Major facilitator Superfamily
OKBOLDLM_00520 2.8e-219 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
OKBOLDLM_00521 6.2e-154 K Helix-turn-helix XRE-family like proteins
OKBOLDLM_00522 1.1e-122 ydhB S membrane transporter protein
OKBOLDLM_00523 2e-77 bltD 2.3.1.57 K FR47-like protein
OKBOLDLM_00524 2.6e-141 bltR K helix_turn_helix, mercury resistance
OKBOLDLM_00525 3e-143 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
OKBOLDLM_00526 9.3e-107 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
OKBOLDLM_00527 7.5e-105 S Alpha/beta hydrolase family
OKBOLDLM_00528 5.7e-165 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
OKBOLDLM_00529 1.3e-112 ydhC K FCD
OKBOLDLM_00530 1.2e-55 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
OKBOLDLM_00531 2.5e-81 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
OKBOLDLM_00532 3.4e-27 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
OKBOLDLM_00534 2.5e-245 pbpE V Beta-lactamase
OKBOLDLM_00536 1.2e-97 ydhK M Protein of unknown function (DUF1541)
OKBOLDLM_00537 3.2e-193 pbuE EGP Major facilitator Superfamily
OKBOLDLM_00538 3.1e-130 ydhQ K UTRA
OKBOLDLM_00539 2.1e-112 K FCD
OKBOLDLM_00540 8.2e-208 yeaN P COG2807 Cyanate permease
OKBOLDLM_00541 1.1e-47 sugE P Small Multidrug Resistance protein
OKBOLDLM_00542 3.1e-48 ykkC P Small Multidrug Resistance protein
OKBOLDLM_00543 2e-98 yvdT K Transcriptional regulator
OKBOLDLM_00544 8.2e-293 yveA E amino acid
OKBOLDLM_00545 1.4e-161 ydhU P Catalase
OKBOLDLM_00546 1.7e-81 yndB S Activator of Hsp90 ATPase homolog 1-like protein
OKBOLDLM_00547 1.6e-177 yhfP 1.1.1.1 C Quinone oxidoreductase
OKBOLDLM_00548 4e-246 iolT EGP Major facilitator Superfamily
OKBOLDLM_00552 4.1e-173 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OKBOLDLM_00553 3.2e-83 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
OKBOLDLM_00554 5.1e-122 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
OKBOLDLM_00555 9e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
OKBOLDLM_00556 8.9e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OKBOLDLM_00557 4e-310 ydiF S ABC transporter
OKBOLDLM_00558 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
OKBOLDLM_00559 4.4e-115 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
OKBOLDLM_00560 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
OKBOLDLM_00561 1.2e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OKBOLDLM_00562 1.7e-27 ydiK S Domain of unknown function (DUF4305)
OKBOLDLM_00563 5.3e-125 ydiL S CAAX protease self-immunity
OKBOLDLM_00564 6.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OKBOLDLM_00565 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
OKBOLDLM_00566 2.3e-77 S Phage integrase family
OKBOLDLM_00567 2.4e-30 yqaB E IrrE N-terminal-like domain
OKBOLDLM_00568 1.7e-25 S Protein of unknown function (DUF4064)
OKBOLDLM_00569 1.3e-48
OKBOLDLM_00570 7.9e-16 K Helix-turn-helix XRE-family like proteins
OKBOLDLM_00571 1.5e-12 K Helix-turn-helix XRE-family like proteins
OKBOLDLM_00572 3.8e-32
OKBOLDLM_00573 9.6e-61 S DNA binding
OKBOLDLM_00574 4.2e-85
OKBOLDLM_00576 1.2e-07 S Hypothetical protein Yqai
OKBOLDLM_00578 5.9e-153 yqaJ L YqaJ-like viral recombinase domain
OKBOLDLM_00579 6.4e-127 recT L RecT family
OKBOLDLM_00580 1.4e-29 3.1.3.16 L DnaD domain protein
OKBOLDLM_00581 2.4e-120 xkdC L IstB-like ATP binding protein
OKBOLDLM_00583 2.3e-22 S YopX protein
OKBOLDLM_00584 6.8e-54 S Protein of unknown function (DUF1064)
OKBOLDLM_00586 5e-17 yqaO S Phage-like element PBSX protein XtrA
OKBOLDLM_00588 7.2e-168 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
OKBOLDLM_00590 1.2e-42 S dUTPase
OKBOLDLM_00593 5.6e-07 S YopX protein
OKBOLDLM_00598 3.1e-48
OKBOLDLM_00600 5.3e-19 V VanZ like family
OKBOLDLM_00601 1.6e-67 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
OKBOLDLM_00603 3.9e-12 K Transcriptional regulator
OKBOLDLM_00606 1.5e-71 yqaS L DNA packaging
OKBOLDLM_00607 6.4e-179 S Pfam:Terminase_3C
OKBOLDLM_00608 1.1e-126 S Phage portal protein, SPP1 Gp6-like
OKBOLDLM_00609 1.5e-92 S Phage Mu protein F like protein
OKBOLDLM_00611 5.4e-44 S Phage minor structural protein GP20
OKBOLDLM_00612 2.9e-54 gpG
OKBOLDLM_00615 3.5e-27 S Phage gp6-like head-tail connector protein
OKBOLDLM_00616 9.5e-29 S Phage head-tail joining protein
OKBOLDLM_00617 6.2e-38 S Bacteriophage HK97-gp10, putative tail-component
OKBOLDLM_00618 3.8e-29 S Protein of unknown function (DUF3168)
OKBOLDLM_00619 1.1e-33 S Phage tail tube protein
OKBOLDLM_00620 1.9e-25 S Phage tail assembly chaperone protein, TAC
OKBOLDLM_00621 8.9e-136
OKBOLDLM_00622 8e-08 4.2.2.1 PL8 D Phage tail tape measure protein, TP901 family
OKBOLDLM_00623 3.5e-47
OKBOLDLM_00624 1.6e-202 sidC L Phage minor structural protein
OKBOLDLM_00628 2.4e-30 xhlA S Haemolysin XhlA
OKBOLDLM_00629 4.8e-28 xhlB S SPP1 phage holin
OKBOLDLM_00630 1.4e-120 xlyB 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
OKBOLDLM_00633 0.0 ybfG 3.2.1.132 M Putative peptidoglycan binding domain
OKBOLDLM_00635 5.7e-62
OKBOLDLM_00636 0.0 K NB-ARC domain
OKBOLDLM_00637 3.3e-197 gutB 1.1.1.14 E Dehydrogenase
OKBOLDLM_00638 4.7e-244 gutA G MFS/sugar transport protein
OKBOLDLM_00639 3e-165 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
OKBOLDLM_00640 2.1e-30 yjdJ S Domain of unknown function (DUF4306)
OKBOLDLM_00641 3.1e-111 pspA KT Phage shock protein A
OKBOLDLM_00642 1.7e-174 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OKBOLDLM_00643 1.1e-114 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
OKBOLDLM_00644 2e-143 ydjI S virion core protein (lumpy skin disease virus)
OKBOLDLM_00645 0.0 yrhL I Acyltransferase family
OKBOLDLM_00646 2.6e-139 rsiV S Protein of unknown function (DUF3298)
OKBOLDLM_00647 9.5e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
OKBOLDLM_00648 6.4e-193 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
OKBOLDLM_00649 4.2e-62 ydjM M Lytic transglycolase
OKBOLDLM_00650 1.8e-131 ydjN U Involved in the tonB-independent uptake of proteins
OKBOLDLM_00652 3.2e-34 ydjO S Cold-inducible protein YdjO
OKBOLDLM_00653 9.5e-302 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
OKBOLDLM_00654 3.9e-238 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
OKBOLDLM_00655 2.2e-140 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OKBOLDLM_00656 3e-176 yeaC S COG0714 MoxR-like ATPases
OKBOLDLM_00657 1.2e-198 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
OKBOLDLM_00658 0.0 yebA E COG1305 Transglutaminase-like enzymes
OKBOLDLM_00659 6.2e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
OKBOLDLM_00660 8.3e-88 sigV K Belongs to the sigma-70 factor family. ECF subfamily
OKBOLDLM_00661 2.3e-249 S Domain of unknown function (DUF4179)
OKBOLDLM_00662 8.1e-209 pbuG S permease
OKBOLDLM_00663 2.4e-123 yebC M Membrane
OKBOLDLM_00665 1.5e-92 yebE S UPF0316 protein
OKBOLDLM_00666 9.5e-29 yebG S NETI protein
OKBOLDLM_00667 2.2e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OKBOLDLM_00668 7.7e-219 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OKBOLDLM_00669 1.8e-245 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OKBOLDLM_00670 3.6e-126 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
OKBOLDLM_00671 4.2e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OKBOLDLM_00672 1.2e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OKBOLDLM_00673 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OKBOLDLM_00674 1.3e-268 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OKBOLDLM_00675 8.7e-182 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
OKBOLDLM_00676 5.9e-103 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OKBOLDLM_00677 7.3e-286 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
OKBOLDLM_00678 4.7e-230 purD 6.3.4.13 F Belongs to the GARS family
OKBOLDLM_00679 3.8e-62 K helix_turn_helix ASNC type
OKBOLDLM_00680 4.2e-135 yjeH E Amino acid permease
OKBOLDLM_00681 5.4e-25 S Protein of unknown function (DUF2892)
OKBOLDLM_00682 0.0 yerA 3.5.4.2 F adenine deaminase
OKBOLDLM_00683 2.4e-189 yerB S Protein of unknown function (DUF3048) C-terminal domain
OKBOLDLM_00684 2.4e-50 yerC S protein conserved in bacteria
OKBOLDLM_00685 6.1e-296 yerD 1.4.7.1 E Belongs to the glutamate synthase family
OKBOLDLM_00686 9e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
OKBOLDLM_00687 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
OKBOLDLM_00688 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OKBOLDLM_00689 5.2e-223 camS S COG4851 Protein involved in sex pheromone biosynthesis
OKBOLDLM_00690 5.4e-181 yerI S homoserine kinase type II (protein kinase fold)
OKBOLDLM_00691 3.1e-119 sapB S MgtC SapB transporter
OKBOLDLM_00692 4.9e-263 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OKBOLDLM_00693 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OKBOLDLM_00694 2e-272 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
OKBOLDLM_00695 1.5e-269 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OKBOLDLM_00696 1.1e-147 yerO K Transcriptional regulator
OKBOLDLM_00697 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OKBOLDLM_00698 7.4e-169 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
OKBOLDLM_00699 1.6e-247 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OKBOLDLM_00700 1.9e-310 L Uncharacterized conserved protein (DUF2075)
OKBOLDLM_00701 8.5e-160 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
OKBOLDLM_00702 1.4e-137 cylB V ABC-2 type transporter
OKBOLDLM_00703 2e-38 S Protein of unknown function, DUF600
OKBOLDLM_00704 1.5e-56 S Protein of unknown function, DUF600
OKBOLDLM_00705 1.9e-51 S Protein of unknown function, DUF600
OKBOLDLM_00706 7.8e-198 yobL L nucleic acid phosphodiester bond hydrolysis
OKBOLDLM_00707 1.3e-120 yobL L Belongs to the WXG100 family
OKBOLDLM_00708 1.2e-126 yeeN K transcriptional regulatory protein
OKBOLDLM_00710 1.7e-109 aadK G Streptomycin adenylyltransferase
OKBOLDLM_00711 9.1e-45 cotJA S Spore coat associated protein JA (CotJA)
OKBOLDLM_00712 1.3e-44 cotJB S CotJB protein
OKBOLDLM_00713 2e-103 cotJC P Spore Coat
OKBOLDLM_00714 2.2e-88 yesJ K Acetyltransferase (GNAT) family
OKBOLDLM_00716 3e-114 yetF S membrane
OKBOLDLM_00717 7e-53 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
OKBOLDLM_00718 7e-62 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OKBOLDLM_00719 3.7e-146 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OKBOLDLM_00720 1.4e-20 yezD S Uncharacterized small protein (DUF2292)
OKBOLDLM_00721 2.4e-55 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
OKBOLDLM_00722 2e-104 yetJ S Belongs to the BI1 family
OKBOLDLM_00723 4.9e-85 yetL K helix_turn_helix multiple antibiotic resistance protein
OKBOLDLM_00724 8.1e-194 yetM CH FAD binding domain
OKBOLDLM_00725 1.7e-196 yetN S Protein of unknown function (DUF3900)
OKBOLDLM_00726 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
OKBOLDLM_00728 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
OKBOLDLM_00729 4.3e-146 rfbF 2.7.7.33 JM Nucleotidyl transferase
OKBOLDLM_00730 9.2e-172 yfnG 4.2.1.45 M dehydratase
OKBOLDLM_00731 8.4e-173 yfnF M Nucleotide-diphospho-sugar transferase
OKBOLDLM_00732 1.6e-213 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
OKBOLDLM_00733 4.5e-177 yfnD M Nucleotide-diphospho-sugar transferase
OKBOLDLM_00734 1e-213 fsr P COG0477 Permeases of the major facilitator superfamily
OKBOLDLM_00735 7.6e-242 yfnA E amino acid
OKBOLDLM_00736 2.1e-274 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OKBOLDLM_00737 1.1e-105 yfmS NT chemotaxis protein
OKBOLDLM_00738 6.4e-165 IQ Enoyl-(Acyl carrier protein) reductase
OKBOLDLM_00739 6.5e-201 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OKBOLDLM_00740 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
OKBOLDLM_00741 5.8e-68 yfmP K transcriptional
OKBOLDLM_00742 3.2e-196 yfmO EGP Major facilitator Superfamily
OKBOLDLM_00743 4.6e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
OKBOLDLM_00744 4.3e-203 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
OKBOLDLM_00745 3.7e-51 yfmJ S N-terminal domain of oxidoreductase
OKBOLDLM_00746 5.7e-79 yfmJ S N-terminal domain of oxidoreductase
OKBOLDLM_00747 9e-22 S Protein of unknown function (DUF3212)
OKBOLDLM_00748 1.3e-57 yflT S Heat induced stress protein YflT
OKBOLDLM_00749 2e-233 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
OKBOLDLM_00750 1e-233 yflS P Sodium:sulfate symporter transmembrane region
OKBOLDLM_00751 3.7e-26 Q PFAM Collagen triple helix
OKBOLDLM_00755 1.2e-19 Q calcium- and calmodulin-responsive adenylate cyclase activity
OKBOLDLM_00756 5.2e-76 M1-820 Q Collagen triple helix repeat (20 copies)
OKBOLDLM_00757 0.0 ywpD T PhoQ Sensor
OKBOLDLM_00758 4.8e-151 M1-574 T Transcriptional regulatory protein, C terminal
OKBOLDLM_00759 0.0 M1-568 M cell wall anchor domain
OKBOLDLM_00760 0.0 M1-568 M cell wall anchor domain
OKBOLDLM_00761 4.6e-80 srtA 3.4.22.70 M Sortase family
OKBOLDLM_00762 6.9e-252 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
OKBOLDLM_00763 6e-115 citT T response regulator
OKBOLDLM_00764 4.9e-171 yflP S Tripartite tricarboxylate transporter family receptor
OKBOLDLM_00765 7.4e-223 citM C Citrate transporter
OKBOLDLM_00766 4.6e-143 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
OKBOLDLM_00767 1.9e-211 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
OKBOLDLM_00768 1.3e-41 acyP 3.6.1.7 C Belongs to the acylphosphatase family
OKBOLDLM_00769 2.3e-119 yflK S protein conserved in bacteria
OKBOLDLM_00770 1.5e-14 yflJ S Protein of unknown function (DUF2639)
OKBOLDLM_00771 1.6e-18 yflI
OKBOLDLM_00772 9e-50 yflH S Protein of unknown function (DUF3243)
OKBOLDLM_00773 6.8e-136 map 3.4.11.18 E Methionine aminopeptidase
OKBOLDLM_00774 2.4e-240 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
OKBOLDLM_00775 8.2e-73 yfmQ S Uncharacterised protein from bacillus cereus group
OKBOLDLM_00776 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
OKBOLDLM_00777 4.7e-61 yhdN S Domain of unknown function (DUF1992)
OKBOLDLM_00778 4.5e-76 cotP O Belongs to the small heat shock protein (HSP20) family
OKBOLDLM_00779 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
OKBOLDLM_00780 1.2e-39 ydgB S Spore germination protein gerPA/gerPF
OKBOLDLM_00781 3.1e-238 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OKBOLDLM_00782 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
OKBOLDLM_00783 6.1e-126 treR K transcriptional
OKBOLDLM_00784 4.6e-120 yfkO C nitroreductase
OKBOLDLM_00785 2.5e-117 yibF S YibE/F-like protein
OKBOLDLM_00786 6.8e-185 yibE S YibE/F-like protein
OKBOLDLM_00787 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
OKBOLDLM_00788 4.2e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
OKBOLDLM_00789 2.6e-178 K helix_turn _helix lactose operon repressor
OKBOLDLM_00790 3.2e-161 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OKBOLDLM_00791 4e-128 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
OKBOLDLM_00792 3.1e-157 ydiM EGP Major facilitator Superfamily
OKBOLDLM_00793 4.1e-17 ydiM EGP Major facilitator Superfamily
OKBOLDLM_00794 3.9e-28 yfkK S Belongs to the UPF0435 family
OKBOLDLM_00795 2.2e-79 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OKBOLDLM_00796 4.4e-47 yfkI S gas vesicle protein
OKBOLDLM_00797 7.1e-142 yihY S Belongs to the UPF0761 family
OKBOLDLM_00798 1.1e-214 ycaD EGP COG0477 Permeases of the major facilitator superfamily
OKBOLDLM_00799 7.4e-181 cax P COG0387 Ca2 H antiporter
OKBOLDLM_00800 1.1e-139 yfkD S YfkD-like protein
OKBOLDLM_00801 5.4e-142 yfkC M Mechanosensitive ion channel
OKBOLDLM_00802 2.1e-218 yfkA S YfkB-like domain
OKBOLDLM_00803 4.9e-27 yfjT
OKBOLDLM_00804 4.9e-153 pdaA G deacetylase
OKBOLDLM_00805 2.2e-68 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
OKBOLDLM_00806 1.8e-28
OKBOLDLM_00807 2.5e-183 corA P Mediates influx of magnesium ions
OKBOLDLM_00808 2.8e-157 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OKBOLDLM_00809 3.4e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OKBOLDLM_00810 1.3e-79 O Subtilase family
OKBOLDLM_00811 1.3e-246 lmrA 3.6.3.44 V ABC transporter
OKBOLDLM_00812 0.0 KLT Protein kinase domain
OKBOLDLM_00820 4.7e-45 S YfzA-like protein
OKBOLDLM_00821 2.4e-189 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OKBOLDLM_00822 6e-79 yfjM S Psort location Cytoplasmic, score
OKBOLDLM_00823 2.5e-186 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
OKBOLDLM_00824 2e-186 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
OKBOLDLM_00825 6.8e-207 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OKBOLDLM_00826 3.9e-238 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
OKBOLDLM_00827 5.4e-268 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
OKBOLDLM_00828 1.3e-33 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
OKBOLDLM_00829 3.2e-15 sspH S Belongs to the SspH family
OKBOLDLM_00830 1e-259 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
OKBOLDLM_00831 4.3e-138 glvR F Helix-turn-helix domain, rpiR family
OKBOLDLM_00832 2.4e-292 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OKBOLDLM_00833 0.0 M Peptidase_G2, IMC autoproteolytic cleavage domain
OKBOLDLM_00834 1.9e-303 yfiB3 V ABC transporter
OKBOLDLM_00835 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
OKBOLDLM_00836 9.2e-63 mhqP S DoxX
OKBOLDLM_00837 1.5e-155 yfiE 1.13.11.2 S glyoxalase
OKBOLDLM_00838 3.7e-77 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
OKBOLDLM_00839 1.7e-70 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
OKBOLDLM_00840 2e-92 padR K transcriptional
OKBOLDLM_00841 9.7e-101 1.6.5.2 S NADPH-dependent FMN reductase
OKBOLDLM_00842 8.5e-172 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
OKBOLDLM_00843 2.2e-44 yrdF K ribonuclease inhibitor
OKBOLDLM_00844 6.1e-94 yfiT S Belongs to the metal hydrolase YfiT family
OKBOLDLM_00845 9.2e-284 yfiU EGP Major facilitator Superfamily
OKBOLDLM_00846 2.4e-78 yfiV K transcriptional
OKBOLDLM_00847 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OKBOLDLM_00848 5.5e-153 yfhB 5.3.3.17 S PhzF family
OKBOLDLM_00849 5.9e-103 yfhC C nitroreductase
OKBOLDLM_00850 1e-24 yfhD S YfhD-like protein
OKBOLDLM_00852 2.1e-163 yfhF S nucleoside-diphosphate sugar epimerase
OKBOLDLM_00853 3.1e-139 recX 2.4.1.337 GT4 S Modulates RecA activity
OKBOLDLM_00854 4.7e-46 yfhH S Protein of unknown function (DUF1811)
OKBOLDLM_00855 5e-177 yfhI EGP Major facilitator Superfamily
OKBOLDLM_00857 1.7e-157 mpr 3.4.21.19 M Belongs to the peptidase S1B family
OKBOLDLM_00858 1.4e-43 yfhJ S WVELL protein
OKBOLDLM_00859 1.2e-86 batE T Bacterial SH3 domain homologues
OKBOLDLM_00860 2e-31 yfhL S SdpI/YhfL protein family
OKBOLDLM_00861 6.1e-123 yfhM S Alpha/beta hydrolase family
OKBOLDLM_00862 1.1e-183 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OKBOLDLM_00863 0.0 yfhO S Bacterial membrane protein YfhO
OKBOLDLM_00864 5.9e-180 yfhP S membrane-bound metal-dependent
OKBOLDLM_00865 1.4e-203 mutY L A G-specific
OKBOLDLM_00866 1.8e-36 yfhS
OKBOLDLM_00867 2e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OKBOLDLM_00869 1.5e-37 ygaB S YgaB-like protein
OKBOLDLM_00870 2.2e-104 ygaC J Belongs to the UPF0374 family
OKBOLDLM_00871 3.1e-301 ygaD V ABC transporter
OKBOLDLM_00872 5e-177 ygaE S Membrane
OKBOLDLM_00873 1.1e-242 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
OKBOLDLM_00874 5e-84 bcp 1.11.1.15 O Peroxiredoxin
OKBOLDLM_00875 3.1e-80 perR P Belongs to the Fur family
OKBOLDLM_00876 2.1e-55 ygzB S UPF0295 protein
OKBOLDLM_00877 8.5e-162 ygxA S Nucleotidyltransferase-like
OKBOLDLM_00882 7.8e-08
OKBOLDLM_00890 1.6e-08
OKBOLDLM_00894 6.8e-132 L Phage integrase family
OKBOLDLM_00895 7.3e-70
OKBOLDLM_00898 1.1e-28 K Helix-turn-helix XRE-family like proteins
OKBOLDLM_00900 2.2e-38 S Domain of unknown function (DUF771)
OKBOLDLM_00902 2e-83 ybl78 L Conserved phage C-terminus (Phg_2220_C)
OKBOLDLM_00903 3.4e-35 dnaC L IstB-like ATP binding protein
OKBOLDLM_00906 2e-28
OKBOLDLM_00909 1.6e-15 yqaO S Phage-like element PBSX protein XtrA
OKBOLDLM_00910 1.2e-27
OKBOLDLM_00912 4.4e-168 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
OKBOLDLM_00914 1.6e-46 S dUTPase
OKBOLDLM_00919 2.5e-53 wecC 1.1.1.336 M ArpU family transcriptional regulator
OKBOLDLM_00920 1e-72 L Phage integrase family
OKBOLDLM_00921 6.9e-09 ftsK D PFAM cell divisionFtsK SpoIIIE
OKBOLDLM_00925 1.8e-16 V HNH endonuclease
OKBOLDLM_00926 3.6e-45
OKBOLDLM_00927 8.9e-277 L Phage Terminase
OKBOLDLM_00928 3.5e-127 S Phage portal protein
OKBOLDLM_00929 1.4e-16 S Phage portal protein
OKBOLDLM_00930 1.1e-84 clpP 3.4.21.92 OU Clp protease
OKBOLDLM_00931 1.2e-140 S Phage capsid family
OKBOLDLM_00933 2e-21
OKBOLDLM_00934 1.5e-22 S Phage head-tail joining protein
OKBOLDLM_00935 5.8e-18
OKBOLDLM_00936 7e-10 S TIGRFAM phage protein, HK97 gp10 family
OKBOLDLM_00937 6.4e-47 S phage major tail protein, phi13 family
OKBOLDLM_00940 9.4e-142 D Phage-related minor tail protein
OKBOLDLM_00941 1.2e-40 S Phage tail protein
OKBOLDLM_00942 1e-103 mur1 NU Prophage endopeptidase tail
OKBOLDLM_00943 1e-284 M Pectate lyase superfamily protein
OKBOLDLM_00944 2.5e-143 S Domain of unknown function (DUF2479)
OKBOLDLM_00946 2.3e-09 S Phage uncharacterised protein (Phage_XkdX)
OKBOLDLM_00947 6.9e-61 S Pfam:Phage_holin_4_1
OKBOLDLM_00948 5e-69 3.5.1.28 M Ami_2
OKBOLDLM_00949 2e-16
OKBOLDLM_00950 1.4e-39
OKBOLDLM_00952 5.9e-275 C Na+/H+ antiporter family
OKBOLDLM_00953 1.8e-122 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
OKBOLDLM_00954 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OKBOLDLM_00955 1.3e-246 ygaK C Berberine and berberine like
OKBOLDLM_00957 6.4e-230 oppA5 E PFAM extracellular solute-binding protein family 5
OKBOLDLM_00958 3.5e-145 appB P Binding-protein-dependent transport system inner membrane component
OKBOLDLM_00959 4.1e-127 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OKBOLDLM_00960 9.8e-135 oppD3 P Belongs to the ABC transporter superfamily
OKBOLDLM_00961 2.9e-131 oppF3 E Belongs to the ABC transporter superfamily
OKBOLDLM_00962 4e-286 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
OKBOLDLM_00963 4.7e-179 S Amidohydrolase
OKBOLDLM_00964 4.3e-138 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
OKBOLDLM_00965 5e-171 ssuA M Sulfonate ABC transporter
OKBOLDLM_00966 2.4e-142 ssuC P ABC transporter (permease)
OKBOLDLM_00967 1.8e-212 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
OKBOLDLM_00969 3.9e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OKBOLDLM_00970 8.9e-78 ygaO
OKBOLDLM_00971 1.8e-22 K Transcriptional regulator
OKBOLDLM_00973 4.2e-107 yhzB S B3/4 domain
OKBOLDLM_00974 6.2e-221 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OKBOLDLM_00975 2.9e-168 yhbB S Putative amidase domain
OKBOLDLM_00976 2.2e-84 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
OKBOLDLM_00977 3.2e-102 yhbD K Protein of unknown function (DUF4004)
OKBOLDLM_00978 3.6e-54 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
OKBOLDLM_00979 1.3e-56 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
OKBOLDLM_00981 0.0 prkA T Ser protein kinase
OKBOLDLM_00982 1.7e-213 yhbH S Belongs to the UPF0229 family
OKBOLDLM_00983 8.5e-58 yhbI K DNA-binding transcription factor activity
OKBOLDLM_00984 2.9e-95 yhbJ V COG1566 Multidrug resistance efflux pump
OKBOLDLM_00985 4.1e-284 yhcA EGP Major facilitator Superfamily
OKBOLDLM_00986 1e-98 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
OKBOLDLM_00987 5.3e-49 yhcC
OKBOLDLM_00988 3.6e-52
OKBOLDLM_00989 1.7e-58 yhcF K Transcriptional regulator
OKBOLDLM_00990 2.8e-115 yhcG V ABC transporter, ATP-binding protein
OKBOLDLM_00991 1.9e-164 yhcH V ABC transporter, ATP-binding protein
OKBOLDLM_00992 7.9e-158 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
OKBOLDLM_00993 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
OKBOLDLM_00994 4.5e-125 metQ M Belongs to the nlpA lipoprotein family
OKBOLDLM_00995 4e-182 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
OKBOLDLM_00996 2.4e-227 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OKBOLDLM_00997 6.9e-40 amaB 3.5.1.6, 3.5.1.87 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
OKBOLDLM_00998 4.4e-38 yhcM
OKBOLDLM_00999 6.3e-74 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OKBOLDLM_01000 1.3e-154 yhcP
OKBOLDLM_01001 9.4e-113 yhcQ M Spore coat protein
OKBOLDLM_01002 1.5e-297 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
OKBOLDLM_01003 6.9e-99 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
OKBOLDLM_01004 3.9e-162 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OKBOLDLM_01005 2.6e-62 yhcU S Family of unknown function (DUF5365)
OKBOLDLM_01006 8.4e-67 yhcV S COG0517 FOG CBS domain
OKBOLDLM_01007 1e-122 yhcW 5.4.2.6 S hydrolase
OKBOLDLM_01008 1.9e-302 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
OKBOLDLM_01009 2.6e-255 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OKBOLDLM_01010 1e-99 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
OKBOLDLM_01011 1.7e-143 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
OKBOLDLM_01012 8.9e-289 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OKBOLDLM_01013 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OKBOLDLM_01014 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
OKBOLDLM_01015 1.3e-194 yhcY 2.7.13.3 T Histidine kinase
OKBOLDLM_01016 2e-107 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OKBOLDLM_01017 2.7e-83 azr 1.7.1.6 S NADPH-dependent FMN reductase
OKBOLDLM_01018 8e-38 yhdB S YhdB-like protein
OKBOLDLM_01019 1.3e-51 yhdC S Protein of unknown function (DUF3889)
OKBOLDLM_01020 2.3e-201 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
OKBOLDLM_01021 2.6e-71 nsrR K Transcriptional regulator
OKBOLDLM_01022 3.5e-248 ygxB M Conserved TM helix
OKBOLDLM_01023 4.2e-264 ycgB S Stage V sporulation protein R
OKBOLDLM_01024 6.2e-252 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
OKBOLDLM_01025 9.5e-123 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
OKBOLDLM_01026 1.3e-157 citR K Transcriptional regulator
OKBOLDLM_01027 1.6e-197 citA 2.3.3.1 C Belongs to the citrate synthase family
OKBOLDLM_01028 3.1e-156 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OKBOLDLM_01029 6.1e-247 yhdG E amino acid
OKBOLDLM_01030 1.6e-196 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
OKBOLDLM_01031 8.1e-45 yhdK S Sigma-M inhibitor protein
OKBOLDLM_01032 7.1e-195 yhdL S Sigma factor regulator N-terminal
OKBOLDLM_01033 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
OKBOLDLM_01034 5.8e-106 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
OKBOLDLM_01035 4e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
OKBOLDLM_01036 1.8e-69 cueR K transcriptional
OKBOLDLM_01037 1.5e-217 yhdR 2.6.1.1 E Aminotransferase
OKBOLDLM_01038 3.3e-228 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
OKBOLDLM_01039 4.2e-248 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
OKBOLDLM_01040 8.8e-49 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OKBOLDLM_01041 3.4e-54 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OKBOLDLM_01042 1.2e-121 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
OKBOLDLM_01044 2.1e-197 yhdY M Mechanosensitive ion channel
OKBOLDLM_01045 9.1e-133 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
OKBOLDLM_01046 1.4e-150 yheN G deacetylase
OKBOLDLM_01047 3.9e-148 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
OKBOLDLM_01048 3.7e-97 pksA K Transcriptional regulator
OKBOLDLM_01049 4.1e-90 ymcC S Membrane
OKBOLDLM_01050 1.3e-82 T universal stress protein
OKBOLDLM_01051 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
OKBOLDLM_01052 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
OKBOLDLM_01053 3.2e-99 yheG GM NAD(P)H-binding
OKBOLDLM_01055 8.4e-28 sspB S spore protein
OKBOLDLM_01056 1.9e-35 yheE S Family of unknown function (DUF5342)
OKBOLDLM_01057 1.1e-248 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
OKBOLDLM_01058 6.1e-202 yheC HJ YheC/D like ATP-grasp
OKBOLDLM_01059 8.5e-199 yheB S Belongs to the UPF0754 family
OKBOLDLM_01060 6.3e-52 yheA S Belongs to the UPF0342 family
OKBOLDLM_01061 2.7e-152 yhaX S haloacid dehalogenase-like hydrolase
OKBOLDLM_01062 1.1e-291 hemZ H coproporphyrinogen III oxidase
OKBOLDLM_01063 1.1e-245 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
OKBOLDLM_01064 2.5e-204 yhaU P COG0475 Kef-type K transport systems, membrane components
OKBOLDLM_01065 1.9e-86 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
OKBOLDLM_01067 4.2e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
OKBOLDLM_01068 1.2e-14 S YhzD-like protein
OKBOLDLM_01069 5.9e-163 yhaQ S ABC transporter, ATP-binding protein
OKBOLDLM_01070 1.7e-203 yhaP CP COG1668 ABC-type Na efflux pump, permease component
OKBOLDLM_01071 9.1e-231 yhaO L DNA repair exonuclease
OKBOLDLM_01072 0.0 yhaN L AAA domain
OKBOLDLM_01073 1.1e-175 yhaM L Shows a 3'-5' exoribonuclease activity
OKBOLDLM_01074 2.3e-31 yhaL S Sporulation protein YhaL
OKBOLDLM_01075 3.2e-113 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
OKBOLDLM_01076 1e-93 yhaK S Putative zincin peptidase
OKBOLDLM_01077 9.9e-55 yhaI S Protein of unknown function (DUF1878)
OKBOLDLM_01078 1.5e-109 hpr K Negative regulator of protease production and sporulation
OKBOLDLM_01079 9e-38 yhaH S YtxH-like protein
OKBOLDLM_01080 2e-17
OKBOLDLM_01081 1.3e-74 trpP S Tryptophan transporter TrpP
OKBOLDLM_01082 1.5e-197 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OKBOLDLM_01083 2.4e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
OKBOLDLM_01084 4.4e-135 ecsA V transporter (ATP-binding protein)
OKBOLDLM_01085 5.7e-217 ecsB U ABC transporter
OKBOLDLM_01086 1.1e-116 ecsC S EcsC protein family
OKBOLDLM_01087 1.4e-215 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
OKBOLDLM_01088 2.5e-237 yhfA C membrane
OKBOLDLM_01089 6e-88 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
OKBOLDLM_01090 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
OKBOLDLM_01091 1.9e-198 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OKBOLDLM_01092 1.7e-176 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
OKBOLDLM_01093 6.6e-273 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
OKBOLDLM_01094 3.5e-100 yhgD K Transcriptional regulator
OKBOLDLM_01095 1.6e-255 yhgE S YhgE Pip N-terminal domain protein
OKBOLDLM_01096 1.3e-176 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OKBOLDLM_01098 1.5e-194 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
OKBOLDLM_01099 1.2e-225 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OKBOLDLM_01100 6.2e-134 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
OKBOLDLM_01101 1.7e-187 lplJ 6.3.1.20 H Lipoate-protein ligase
OKBOLDLM_01102 5.7e-107 yhfK GM NmrA-like family
OKBOLDLM_01103 1.7e-295 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
OKBOLDLM_01104 8.1e-64 yhfM
OKBOLDLM_01105 5.4e-231 yhfN 3.4.24.84 O Peptidase M48
OKBOLDLM_01106 1.6e-200 aprE 3.4.21.62 O Belongs to the peptidase S8 family
OKBOLDLM_01107 7e-129 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
OKBOLDLM_01108 2.7e-100 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
OKBOLDLM_01109 1.4e-193 vraB 2.3.1.9 I Belongs to the thiolase family
OKBOLDLM_01110 6.2e-263 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
OKBOLDLM_01111 3.1e-85 bioY S BioY family
OKBOLDLM_01112 2.4e-197 hemAT NT chemotaxis protein
OKBOLDLM_01113 1e-262 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
OKBOLDLM_01114 1.4e-158 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OKBOLDLM_01115 1.2e-30 yhzC S IDEAL
OKBOLDLM_01116 4.2e-109 comK K Competence transcription factor
OKBOLDLM_01117 4.1e-57 frataxin S Domain of unknown function (DU1801)
OKBOLDLM_01118 6.1e-171 els S Acetyltransferase, GNAT family
OKBOLDLM_01119 1.2e-121 yrpD S Domain of unknown function, YrpD
OKBOLDLM_01120 7.8e-42 yhjA S Excalibur calcium-binding domain
OKBOLDLM_01121 3.3e-47 S Belongs to the UPF0145 family
OKBOLDLM_01122 1.2e-261 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OKBOLDLM_01123 3.1e-27 yhjC S Protein of unknown function (DUF3311)
OKBOLDLM_01124 1.4e-47 yhjD
OKBOLDLM_01125 1e-105 yhjE S SNARE associated Golgi protein
OKBOLDLM_01126 6.6e-90 sipV 3.4.21.89 U Belongs to the peptidase S26 family
OKBOLDLM_01127 6.3e-115 yhjG CH FAD binding domain
OKBOLDLM_01128 3.2e-127 yhjG CH FAD binding domain
OKBOLDLM_01129 6.1e-91 yhjH K helix_turn_helix multiple antibiotic resistance protein
OKBOLDLM_01130 7.9e-184 abrB S membrane
OKBOLDLM_01131 2.6e-198 blt EGP Major facilitator Superfamily
OKBOLDLM_01132 3.5e-106 K QacR-like protein, C-terminal region
OKBOLDLM_01133 1.4e-82 yhjR S Rubrerythrin
OKBOLDLM_01134 1.2e-118 ydfS S Protein of unknown function (DUF421)
OKBOLDLM_01135 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
OKBOLDLM_01136 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
OKBOLDLM_01137 9e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
OKBOLDLM_01138 0.0 sbcC L COG0419 ATPase involved in DNA repair
OKBOLDLM_01139 3.9e-50 yisB V COG1403 Restriction endonuclease
OKBOLDLM_01140 1.7e-31 gerPF S Spore germination protein gerPA/gerPF
OKBOLDLM_01141 1e-58 gerPE S Spore germination protein GerPE
OKBOLDLM_01142 7.7e-22 gerPD S Spore germination protein
OKBOLDLM_01143 5e-60 gerPC S Spore germination protein
OKBOLDLM_01144 8.4e-34 gerPA S Spore germination protein
OKBOLDLM_01145 1.6e-08 yisI S Spo0E like sporulation regulatory protein
OKBOLDLM_01146 2e-166 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
OKBOLDLM_01147 1.9e-59 yisL S UPF0344 protein
OKBOLDLM_01148 0.0 wprA O Belongs to the peptidase S8 family
OKBOLDLM_01149 3.1e-90 yisN S Protein of unknown function (DUF2777)
OKBOLDLM_01150 0.0 asnO 6.3.5.4 E Asparagine synthase
OKBOLDLM_01151 7e-117 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
OKBOLDLM_01152 1e-241 yisQ V Mate efflux family protein
OKBOLDLM_01153 8e-157 yisR K Transcriptional regulator
OKBOLDLM_01154 8.6e-142 purR K helix_turn _helix lactose operon repressor
OKBOLDLM_01155 4.4e-154 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
OKBOLDLM_01156 5.2e-77 yisT S DinB family
OKBOLDLM_01157 1e-73 argO S Lysine exporter protein LysE YggA
OKBOLDLM_01158 1.5e-187 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OKBOLDLM_01159 2.4e-49 mcbG S Pentapeptide repeats (9 copies)
OKBOLDLM_01160 6e-76 yjcF S Acetyltransferase (GNAT) domain
OKBOLDLM_01161 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
OKBOLDLM_01162 1.9e-54 yajQ S Belongs to the UPF0234 family
OKBOLDLM_01163 3.9e-156 cvfB S protein conserved in bacteria
OKBOLDLM_01164 5e-147 yufN S ABC transporter substrate-binding protein PnrA-like
OKBOLDLM_01165 2.9e-116 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
OKBOLDLM_01166 1.6e-46 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
OKBOLDLM_01167 1.8e-229 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
OKBOLDLM_01168 8.2e-154 yitS S protein conserved in bacteria
OKBOLDLM_01169 8.7e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
OKBOLDLM_01170 1.2e-79 ipi S Intracellular proteinase inhibitor
OKBOLDLM_01171 2.8e-25 S Protein of unknown function (DUF3813)
OKBOLDLM_01172 2e-07
OKBOLDLM_01173 4.4e-149 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
OKBOLDLM_01174 3.2e-141 yjfP S COG1073 Hydrolases of the alpha beta superfamily
OKBOLDLM_01175 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
OKBOLDLM_01176 3.6e-70 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
OKBOLDLM_01177 5.1e-265 yitY C D-arabinono-1,4-lactone oxidase
OKBOLDLM_01178 9.4e-87 norB G Major Facilitator Superfamily
OKBOLDLM_01179 1.4e-192 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OKBOLDLM_01180 3.2e-220 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OKBOLDLM_01181 9.8e-130 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
OKBOLDLM_01182 2.2e-210 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
OKBOLDLM_01183 1.4e-195 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
OKBOLDLM_01184 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
OKBOLDLM_01185 3.4e-172 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OKBOLDLM_01186 2.1e-27 yjzC S YjzC-like protein
OKBOLDLM_01187 6.3e-22 yjzD S Protein of unknown function (DUF2929)
OKBOLDLM_01188 4.4e-132 yjaU I carboxylic ester hydrolase activity
OKBOLDLM_01189 5.5e-98 yjaV
OKBOLDLM_01190 2e-163 med S Transcriptional activator protein med
OKBOLDLM_01191 3.3e-26 comZ S ComZ
OKBOLDLM_01193 1.6e-171 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OKBOLDLM_01194 1.2e-230 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
OKBOLDLM_01195 2.1e-140 yjaZ O Zn-dependent protease
OKBOLDLM_01196 1.9e-178 appD P Belongs to the ABC transporter superfamily
OKBOLDLM_01197 1.7e-182 appF E Belongs to the ABC transporter superfamily
OKBOLDLM_01198 0.0 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
OKBOLDLM_01199 4.8e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OKBOLDLM_01200 1.8e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OKBOLDLM_01201 5.5e-146 yjbA S Belongs to the UPF0736 family
OKBOLDLM_01202 8e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
OKBOLDLM_01203 0.0 oppA E ABC transporter substrate-binding protein
OKBOLDLM_01204 7.8e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OKBOLDLM_01205 6.5e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OKBOLDLM_01206 1.2e-199 oppD P Belongs to the ABC transporter superfamily
OKBOLDLM_01207 8.8e-170 oppF E Belongs to the ABC transporter superfamily
OKBOLDLM_01208 9.2e-220 S Putative glycosyl hydrolase domain
OKBOLDLM_01209 2.9e-102 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OKBOLDLM_01210 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
OKBOLDLM_01211 1.1e-108 yjbE P Integral membrane protein TerC family
OKBOLDLM_01212 5e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
OKBOLDLM_01213 1.9e-201 yjbF S Competence protein
OKBOLDLM_01214 0.0 pepF E oligoendopeptidase F
OKBOLDLM_01215 5.8e-19
OKBOLDLM_01216 2.6e-166 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
OKBOLDLM_01217 5.9e-70 yjbI S Bacterial-like globin
OKBOLDLM_01218 7.9e-107 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
OKBOLDLM_01219 7.1e-93 yjbK S protein conserved in bacteria
OKBOLDLM_01220 5e-60 yjbL S Belongs to the UPF0738 family
OKBOLDLM_01221 1.9e-107 yjbM 2.7.6.5 S GTP pyrophosphokinase
OKBOLDLM_01222 3.9e-150 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OKBOLDLM_01223 4.1e-156 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OKBOLDLM_01224 2.7e-48 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
OKBOLDLM_01225 1.9e-80 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
OKBOLDLM_01226 1.8e-307 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
OKBOLDLM_01227 8.7e-133 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OKBOLDLM_01228 4e-102 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
OKBOLDLM_01229 1.8e-201 thiO 1.4.3.19 E Glycine oxidase
OKBOLDLM_01230 7.5e-29 thiS H Thiamine biosynthesis
OKBOLDLM_01231 2.6e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
OKBOLDLM_01232 4.3e-178 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
OKBOLDLM_01233 2.6e-141 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
OKBOLDLM_01234 6.8e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
OKBOLDLM_01235 5.4e-72 yjbX S Spore coat protein
OKBOLDLM_01236 1.8e-80 cotZ S Spore coat protein
OKBOLDLM_01237 1.3e-92 cotY S Spore coat protein Z
OKBOLDLM_01238 1.3e-69 cotX S Spore Coat Protein X and V domain
OKBOLDLM_01239 1.4e-21 cotW
OKBOLDLM_01240 6.3e-53 cotV S Spore Coat Protein X and V domain
OKBOLDLM_01241 2.8e-55 yjcA S Protein of unknown function (DUF1360)
OKBOLDLM_01245 8.4e-38 spoVIF S Stage VI sporulation protein F
OKBOLDLM_01246 0.0 yjcD 3.6.4.12 L DNA helicase
OKBOLDLM_01247 6.2e-33
OKBOLDLM_01248 2.4e-125 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
OKBOLDLM_01249 1.7e-120 S ABC-2 type transporter
OKBOLDLM_01250 2.1e-129 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
OKBOLDLM_01251 8.8e-34 K SpoVT / AbrB like domain
OKBOLDLM_01252 2e-71 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OKBOLDLM_01253 7.8e-91 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
OKBOLDLM_01254 1.2e-121 yjcH P COG2382 Enterochelin esterase and related enzymes
OKBOLDLM_01255 1.8e-209 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
OKBOLDLM_01256 1.7e-213 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
OKBOLDLM_01258 5.3e-40
OKBOLDLM_01259 2.6e-74 yobL S Bacterial EndoU nuclease
OKBOLDLM_01260 4.5e-31
OKBOLDLM_01261 7.1e-90 yokH G SMI1 / KNR4 family
OKBOLDLM_01262 5.5e-103 1.1.1.169 H 2-dehydropantoate 2-reductase
OKBOLDLM_01263 4.3e-22 yokK S SMI1 / KNR4 family
OKBOLDLM_01264 3e-62 H Acetyltransferase (GNAT) domain
OKBOLDLM_01265 3.7e-25
OKBOLDLM_01266 1.1e-197 K Psort location Cytoplasmic, score
OKBOLDLM_01267 6.3e-299 K Psort location Cytoplasmic, score
OKBOLDLM_01268 3.5e-36 S YolD-like protein
OKBOLDLM_01269 5.8e-46 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OKBOLDLM_01270 2.2e-28 S Bacillus cereus group antimicrobial protein
OKBOLDLM_01275 1.5e-16 N Kelch motif
OKBOLDLM_01277 2e-153 bla 3.5.2.6 V beta-lactamase
OKBOLDLM_01278 3e-44 yjcS S Antibiotic biosynthesis monooxygenase
OKBOLDLM_01279 3e-238 yfjF EGP Belongs to the major facilitator superfamily
OKBOLDLM_01280 2.2e-76 napB K helix_turn_helix multiple antibiotic resistance protein
OKBOLDLM_01281 1.8e-217 ganA 3.2.1.89 G arabinogalactan
OKBOLDLM_01282 3.7e-299 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OKBOLDLM_01283 3.4e-49 lacF 2.7.1.207 G phosphotransferase system
OKBOLDLM_01284 1.6e-279 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
OKBOLDLM_01285 3.7e-137 lacR K COG1349 Transcriptional regulators of sugar metabolism
OKBOLDLM_01286 5.8e-118 5.4.2.6 S Haloacid dehalogenase-like hydrolase
OKBOLDLM_01287 7.6e-34
OKBOLDLM_01288 4.5e-52 K helix_turn_helix multiple antibiotic resistance protein
OKBOLDLM_01289 2.2e-103 yhiD S MgtC SapB transporter
OKBOLDLM_01291 5.4e-20 yjfB S Putative motility protein
OKBOLDLM_01292 5.9e-62 T PhoQ Sensor
OKBOLDLM_01293 2.9e-94 yjgB S Domain of unknown function (DUF4309)
OKBOLDLM_01294 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
OKBOLDLM_01295 9.4e-87 yjgD S Protein of unknown function (DUF1641)
OKBOLDLM_01296 2e-214 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
OKBOLDLM_01297 1.8e-215 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
OKBOLDLM_01298 6.8e-29
OKBOLDLM_01299 4.7e-141 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
OKBOLDLM_01300 2.2e-118 ybbM S transport system, permease component
OKBOLDLM_01301 2.4e-125 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
OKBOLDLM_01302 5.9e-172 yjlA EG Putative multidrug resistance efflux transporter
OKBOLDLM_01303 7.3e-86 yjlB S Cupin domain
OKBOLDLM_01304 7e-66 yjlC S Protein of unknown function (DUF1641)
OKBOLDLM_01305 3.2e-217 yjlD 1.6.99.3 C NADH dehydrogenase
OKBOLDLM_01306 2e-65 uxaC 5.3.1.12 G glucuronate isomerase
OKBOLDLM_01307 5.4e-181 exuR K transcriptional
OKBOLDLM_01308 9.7e-161 uxaA 4.2.1.7, 4.4.1.24 G Altronate
OKBOLDLM_01309 5.2e-87 T Transcriptional regulatory protein, C terminal
OKBOLDLM_01310 1.9e-128 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
OKBOLDLM_01312 6.9e-128 MA20_18170 S membrane transporter protein
OKBOLDLM_01313 4.9e-76 yjoA S DinB family
OKBOLDLM_01314 3.2e-214 S response regulator aspartate phosphatase
OKBOLDLM_01316 1.1e-46 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
OKBOLDLM_01317 2.3e-97 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
OKBOLDLM_01318 6.8e-60 yjqA S Bacterial PH domain
OKBOLDLM_01319 4.8e-100 yjqB S phage-related replication protein
OKBOLDLM_01320 1.5e-106 xkdA E IrrE N-terminal-like domain
OKBOLDLM_01321 2.6e-55 xre K Helix-turn-helix XRE-family like proteins
OKBOLDLM_01323 3.2e-144 xkdC L Bacterial dnaA protein
OKBOLDLM_01326 4.5e-10 yqaO S Phage-like element PBSX protein XtrA
OKBOLDLM_01327 8.5e-82 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
OKBOLDLM_01328 1.5e-109 xtmA L phage terminase small subunit
OKBOLDLM_01329 1.6e-209 xtmB S phage terminase, large subunit
OKBOLDLM_01330 7.4e-240 yqbA S portal protein
OKBOLDLM_01331 7.5e-91 xkdF 2.1.1.72 L Putative phage serine protease XkdF
OKBOLDLM_01332 3e-157 xkdG S Phage capsid family
OKBOLDLM_01333 1.3e-45 yqbG S Protein of unknown function (DUF3199)
OKBOLDLM_01334 3.3e-40 yqbH S Domain of unknown function (DUF3599)
OKBOLDLM_01335 4.1e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
OKBOLDLM_01336 5.8e-58 xkdJ
OKBOLDLM_01337 6.3e-15
OKBOLDLM_01338 2.1e-223 xkdK S Phage tail sheath C-terminal domain
OKBOLDLM_01339 2e-74 xkdM S Phage tail tube protein
OKBOLDLM_01340 1.7e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
OKBOLDLM_01341 3.4e-19
OKBOLDLM_01342 1.6e-191 xkdO L Transglycosylase SLT domain
OKBOLDLM_01343 8.5e-100 xkdP S Lysin motif
OKBOLDLM_01344 2.9e-163 xkdQ 3.2.1.96 G NLP P60 protein
OKBOLDLM_01345 8.5e-33 xkdR S Protein of unknown function (DUF2577)
OKBOLDLM_01346 2.7e-57 xkdS S Protein of unknown function (DUF2634)
OKBOLDLM_01347 1.5e-162 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
OKBOLDLM_01348 4.2e-85 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
OKBOLDLM_01349 6.1e-26
OKBOLDLM_01350 2.1e-160
OKBOLDLM_01352 6.8e-27 xkdX
OKBOLDLM_01353 2.5e-130 xepA
OKBOLDLM_01354 7.4e-37 xhlA S Haemolysin XhlA
OKBOLDLM_01355 9.6e-37 xhlB S SPP1 phage holin
OKBOLDLM_01356 7.6e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OKBOLDLM_01357 8.7e-23 spoIISB S Stage II sporulation protein SB
OKBOLDLM_01358 1.7e-131 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
OKBOLDLM_01359 2.4e-173 pit P phosphate transporter
OKBOLDLM_01360 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
OKBOLDLM_01361 1.4e-240 steT E amino acid
OKBOLDLM_01362 5.3e-178 mhqA E COG0346 Lactoylglutathione lyase and related lyases
OKBOLDLM_01363 1.5e-297 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OKBOLDLM_01364 1.2e-177 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OKBOLDLM_01366 5e-198 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OKBOLDLM_01367 2.3e-263 yubD P Major Facilitator Superfamily
OKBOLDLM_01368 3.6e-154 dppA E D-aminopeptidase
OKBOLDLM_01369 3.5e-158 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OKBOLDLM_01370 5.3e-170 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OKBOLDLM_01371 3e-182 dppD P Belongs to the ABC transporter superfamily
OKBOLDLM_01372 1.4e-308 dppE E ABC transporter substrate-binding protein
OKBOLDLM_01373 1.9e-172 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
OKBOLDLM_01374 1.1e-190 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
OKBOLDLM_01375 2.4e-156 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
OKBOLDLM_01376 4.4e-180 ykfD E Belongs to the ABC transporter superfamily
OKBOLDLM_01377 4.2e-200 pgl 3.1.1.31 G 6-phosphogluconolactonase
OKBOLDLM_01378 1.5e-131 ykgA E Amidinotransferase
OKBOLDLM_01379 8.4e-93 ykhA 3.1.2.20 I Acyl-CoA hydrolase
OKBOLDLM_01380 4.4e-92 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
OKBOLDLM_01381 1.2e-48 ykkC P Multidrug resistance protein
OKBOLDLM_01382 1e-48 ykkD P Multidrug resistance protein
OKBOLDLM_01383 4.4e-166 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
OKBOLDLM_01384 4.4e-200 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OKBOLDLM_01385 3.3e-220 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OKBOLDLM_01386 4.1e-69 ohrA O Organic hydroperoxide resistance protein
OKBOLDLM_01387 7.5e-78 ohrR K COG1846 Transcriptional regulators
OKBOLDLM_01388 7.9e-70 ohrB O Organic hydroperoxide resistance protein
OKBOLDLM_01389 2.9e-51 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OKBOLDLM_01391 6e-205 M Glycosyl transferase family 2
OKBOLDLM_01392 1.1e-105 3.2.1.4 GH5,GH9 K Collagen triple helix repeat
OKBOLDLM_01393 4e-207 hcaT 1.5.1.2 EGP Major facilitator Superfamily
OKBOLDLM_01394 9.9e-118 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
OKBOLDLM_01395 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OKBOLDLM_01396 6.8e-173 isp O Belongs to the peptidase S8 family
OKBOLDLM_01397 7.8e-141 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OKBOLDLM_01398 7.1e-125 ykoC P Cobalt transport protein
OKBOLDLM_01399 8.6e-277 P ABC transporter, ATP-binding protein
OKBOLDLM_01400 9.3e-96 ykoE S ABC-type cobalt transport system, permease component
OKBOLDLM_01401 1.8e-237 ydhD M Glycosyl hydrolase
OKBOLDLM_01403 3e-235 mgtE P Acts as a magnesium transporter
OKBOLDLM_01404 1.6e-52 tnrA K transcriptional
OKBOLDLM_01405 1.9e-16
OKBOLDLM_01406 5.9e-25 ykoL
OKBOLDLM_01407 4.2e-80 ykoM K transcriptional
OKBOLDLM_01408 4.1e-98 ykoP G polysaccharide deacetylase
OKBOLDLM_01409 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
OKBOLDLM_01410 2.8e-149 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
OKBOLDLM_01411 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
OKBOLDLM_01412 4.4e-95 ykoX S membrane-associated protein
OKBOLDLM_01413 5.4e-128 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
OKBOLDLM_01414 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OKBOLDLM_01415 4.5e-118 rsgI S Anti-sigma factor N-terminus
OKBOLDLM_01416 9.6e-26 sspD S small acid-soluble spore protein
OKBOLDLM_01417 9.5e-124 ykrK S Domain of unknown function (DUF1836)
OKBOLDLM_01418 3.9e-154 htpX O Belongs to the peptidase M48B family
OKBOLDLM_01419 6.1e-236 ktrB P COG0168 Trk-type K transport systems, membrane components
OKBOLDLM_01420 3e-111 ydfR S Protein of unknown function (DUF421)
OKBOLDLM_01421 1.2e-19 ykzE
OKBOLDLM_01422 3.8e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
OKBOLDLM_01423 0.0 kinE 2.7.13.3 T Histidine kinase
OKBOLDLM_01424 5.4e-81 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OKBOLDLM_01426 1e-190 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
OKBOLDLM_01427 1.6e-219 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
OKBOLDLM_01428 7.3e-138 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
OKBOLDLM_01429 5.2e-223 mtnE 2.6.1.83 E Aminotransferase
OKBOLDLM_01430 6.9e-223 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
OKBOLDLM_01431 1.6e-131 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
OKBOLDLM_01432 1.3e-109 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
OKBOLDLM_01433 3.6e-91 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
OKBOLDLM_01434 4e-11 S Spo0E like sporulation regulatory protein
OKBOLDLM_01435 1e-268 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
OKBOLDLM_01436 3.2e-77 ykvE K transcriptional
OKBOLDLM_01437 5.1e-121 motB N Flagellar motor protein
OKBOLDLM_01438 7.4e-136 motA N flagellar motor
OKBOLDLM_01439 0.0 clpE O Belongs to the ClpA ClpB family
OKBOLDLM_01440 6.4e-177 ykvI S membrane
OKBOLDLM_01441 4.9e-13
OKBOLDLM_01442 9.3e-146
OKBOLDLM_01443 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OKBOLDLM_01444 2.9e-78 queD 4.1.2.50, 4.2.3.12 H synthase
OKBOLDLM_01445 7.8e-137 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
OKBOLDLM_01446 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OKBOLDLM_01447 1.8e-41 ykvR S Protein of unknown function (DUF3219)
OKBOLDLM_01448 1.7e-24 ykvS S protein conserved in bacteria
OKBOLDLM_01449 2.3e-27
OKBOLDLM_01450 1.1e-104 ykvT 3.5.1.28 M Cell Wall Hydrolase
OKBOLDLM_01451 2.7e-236 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OKBOLDLM_01452 8.3e-82 stoA CO thiol-disulfide
OKBOLDLM_01453 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
OKBOLDLM_01454 5e-204 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
OKBOLDLM_01455 1.9e-170 ykvZ 5.1.1.1 K Transcriptional regulator
OKBOLDLM_01456 8.1e-154 glcT K antiterminator
OKBOLDLM_01457 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OKBOLDLM_01458 2.1e-39 ptsH G phosphocarrier protein HPr
OKBOLDLM_01459 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OKBOLDLM_01460 6.7e-37 splA S Transcriptional regulator
OKBOLDLM_01461 1.8e-192 splB 4.1.99.14 L Spore photoproduct lyase
OKBOLDLM_01462 3.1e-255 mcpC NT chemotaxis protein
OKBOLDLM_01463 2.5e-158 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
OKBOLDLM_01464 1.6e-48
OKBOLDLM_01465 2.2e-113 ykwD J protein with SCP PR1 domains
OKBOLDLM_01466 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
OKBOLDLM_01467 5.4e-288 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
OKBOLDLM_01468 5.7e-214 patA 2.6.1.1 E Aminotransferase
OKBOLDLM_01469 1.4e-09
OKBOLDLM_01470 1.1e-164 cheV 2.7.13.3 T Chemotaxis protein CheV
OKBOLDLM_01471 3.2e-83 ykyB S YkyB-like protein
OKBOLDLM_01472 3.8e-235 ykuC EGP Major facilitator Superfamily
OKBOLDLM_01473 5.1e-87 ykuD S protein conserved in bacteria
OKBOLDLM_01474 7.5e-147 ykuE S Metallophosphoesterase
OKBOLDLM_01475 5.6e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OKBOLDLM_01477 2.4e-231 ykuI T Diguanylate phosphodiesterase
OKBOLDLM_01478 2e-36 ykuJ S protein conserved in bacteria
OKBOLDLM_01479 1.7e-90 ykuK S Ribonuclease H-like
OKBOLDLM_01480 7.3e-26 ykzF S Antirepressor AbbA
OKBOLDLM_01481 1e-75 ykuL S CBS domain
OKBOLDLM_01482 2.3e-167 ccpC K Transcriptional regulator
OKBOLDLM_01483 2.4e-86 fld C Flavodoxin
OKBOLDLM_01484 8.6e-162 ykuO
OKBOLDLM_01485 1.3e-73 fld C Flavodoxin
OKBOLDLM_01486 4.8e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
OKBOLDLM_01487 6.7e-212 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
OKBOLDLM_01488 1.8e-37 ykuS S Belongs to the UPF0180 family
OKBOLDLM_01489 1.6e-138 ykuT M Mechanosensitive ion channel
OKBOLDLM_01491 5.5e-72 ykuV CO thiol-disulfide
OKBOLDLM_01493 3.8e-97 rok K Repressor of ComK
OKBOLDLM_01494 3.3e-146 yknT
OKBOLDLM_01495 2.2e-100 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
OKBOLDLM_01496 4.1e-184 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
OKBOLDLM_01497 1.5e-239 moeA 2.10.1.1 H molybdopterin
OKBOLDLM_01498 1.7e-85 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
OKBOLDLM_01499 6e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
OKBOLDLM_01500 4.1e-31 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OKBOLDLM_01501 7.3e-100 yknW S Yip1 domain
OKBOLDLM_01502 9.9e-155 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OKBOLDLM_01503 5.1e-122 macB V ABC transporter, ATP-binding protein
OKBOLDLM_01504 4e-207 yknZ V ABC transporter (permease)
OKBOLDLM_01505 4.3e-130 fruR K Transcriptional regulator
OKBOLDLM_01506 7.1e-164 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
OKBOLDLM_01507 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
OKBOLDLM_01508 1.5e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
OKBOLDLM_01509 6.4e-36 ykoA
OKBOLDLM_01510 5.5e-308 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
OKBOLDLM_01511 1.3e-157 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OKBOLDLM_01512 9.5e-236 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
OKBOLDLM_01513 1.1e-12 S Uncharacterized protein YkpC
OKBOLDLM_01514 7.7e-183 mreB D Rod-share determining protein MreBH
OKBOLDLM_01515 1e-44 abrB K of stationary sporulation gene expression
OKBOLDLM_01516 9.1e-237 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
OKBOLDLM_01517 1.6e-146 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
OKBOLDLM_01518 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
OKBOLDLM_01519 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OKBOLDLM_01520 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OKBOLDLM_01521 5.3e-30 ykzG S Belongs to the UPF0356 family
OKBOLDLM_01522 2.5e-141 ykrA S hydrolases of the HAD superfamily
OKBOLDLM_01523 1.6e-97 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
OKBOLDLM_01525 3e-66 recN L Putative cell-wall binding lipoprotein
OKBOLDLM_01526 3.8e-183 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
OKBOLDLM_01527 1.2e-177 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
OKBOLDLM_01528 2.1e-225 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OKBOLDLM_01529 2.7e-242 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
OKBOLDLM_01530 6.1e-45 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
OKBOLDLM_01531 1.4e-126 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
OKBOLDLM_01532 5.2e-273 speA 4.1.1.19 E Arginine
OKBOLDLM_01533 5.9e-42 yktA S Belongs to the UPF0223 family
OKBOLDLM_01534 3.5e-117 yktB S Belongs to the UPF0637 family
OKBOLDLM_01535 6.3e-24 ykzI
OKBOLDLM_01536 5.1e-150 suhB 3.1.3.25 G Inositol monophosphatase
OKBOLDLM_01537 1.6e-70 ykzC S Acetyltransferase (GNAT) family
OKBOLDLM_01538 3e-287 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
OKBOLDLM_01539 5.6e-26 ylaA
OKBOLDLM_01540 1.7e-13 sigC S Putative zinc-finger
OKBOLDLM_01541 2e-37 ylaE
OKBOLDLM_01542 6.7e-24 S Family of unknown function (DUF5325)
OKBOLDLM_01543 0.0 typA T GTP-binding protein TypA
OKBOLDLM_01544 6.6e-48 ylaH S YlaH-like protein
OKBOLDLM_01545 1.5e-32 ylaI S protein conserved in bacteria
OKBOLDLM_01546 6.1e-98 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OKBOLDLM_01547 7.8e-244 phoH T ATPase related to phosphate starvation-inducible protein PhoH
OKBOLDLM_01548 2.2e-79 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OKBOLDLM_01549 2e-169 glsA 3.5.1.2 E Belongs to the glutaminase family
OKBOLDLM_01550 8.7e-44 ylaN S Belongs to the UPF0358 family
OKBOLDLM_01551 1.1e-209 ftsW D Belongs to the SEDS family
OKBOLDLM_01552 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
OKBOLDLM_01553 2.5e-164 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
OKBOLDLM_01554 4.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
OKBOLDLM_01555 1.2e-189 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
OKBOLDLM_01556 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OKBOLDLM_01557 1.5e-109 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
OKBOLDLM_01558 2.7e-52 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
OKBOLDLM_01559 1.9e-161 ctaG S cytochrome c oxidase
OKBOLDLM_01560 4.6e-58 ylbA S YugN-like family
OKBOLDLM_01561 1.2e-71 ylbB T COG0517 FOG CBS domain
OKBOLDLM_01562 6.4e-193 ylbC S protein with SCP PR1 domains
OKBOLDLM_01563 1.5e-52 ylbD S Putative coat protein
OKBOLDLM_01564 8.8e-37 ylbE S YlbE-like protein
OKBOLDLM_01565 2.5e-69 ylbF S Belongs to the UPF0342 family
OKBOLDLM_01566 1e-41 ylbG S UPF0298 protein
OKBOLDLM_01567 1.2e-97 rsmD 2.1.1.171 L Methyltransferase
OKBOLDLM_01568 2.1e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OKBOLDLM_01569 3e-210 ylbJ S Sporulation integral membrane protein YlbJ
OKBOLDLM_01570 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
OKBOLDLM_01571 2.6e-183 ylbL T Belongs to the peptidase S16 family
OKBOLDLM_01572 2.2e-220 ylbM S Belongs to the UPF0348 family
OKBOLDLM_01573 5.6e-89 yceD S metal-binding, possibly nucleic acid-binding protein
OKBOLDLM_01574 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
OKBOLDLM_01575 5e-70 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
OKBOLDLM_01576 5.8e-88 ylbP K n-acetyltransferase
OKBOLDLM_01577 2.3e-149 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OKBOLDLM_01578 1.1e-300 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
OKBOLDLM_01579 1.2e-77 mraZ K Belongs to the MraZ family
OKBOLDLM_01580 5.6e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
OKBOLDLM_01581 2.4e-51 ftsL D Essential cell division protein
OKBOLDLM_01582 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
OKBOLDLM_01583 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
OKBOLDLM_01584 1.1e-278 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OKBOLDLM_01585 1.4e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OKBOLDLM_01586 6.7e-251 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OKBOLDLM_01587 2.2e-185 spoVE D Belongs to the SEDS family
OKBOLDLM_01588 1.3e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OKBOLDLM_01589 1.3e-165 murB 1.3.1.98 M cell wall formation
OKBOLDLM_01590 1.3e-126 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
OKBOLDLM_01591 1.7e-227 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
OKBOLDLM_01592 7.5e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OKBOLDLM_01593 0.0 bpr O COG1404 Subtilisin-like serine proteases
OKBOLDLM_01594 7.8e-158 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
OKBOLDLM_01595 1.2e-116 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OKBOLDLM_01596 1.5e-138 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OKBOLDLM_01597 7.9e-143 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
OKBOLDLM_01598 7e-242 argE 3.5.1.16 E Acetylornithine deacetylase
OKBOLDLM_01599 2.2e-38 ylmC S sporulation protein
OKBOLDLM_01600 5.2e-153 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
OKBOLDLM_01601 4.1e-119 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OKBOLDLM_01602 5.7e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
OKBOLDLM_01603 5.2e-41 yggT S membrane
OKBOLDLM_01604 6.3e-137 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
OKBOLDLM_01605 8.9e-68 divIVA D Cell division initiation protein
OKBOLDLM_01606 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OKBOLDLM_01607 3.8e-63 dksA T COG1734 DnaK suppressor protein
OKBOLDLM_01608 1.7e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OKBOLDLM_01609 1.5e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OKBOLDLM_01610 1e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
OKBOLDLM_01611 1.1e-229 pyrP F Xanthine uracil
OKBOLDLM_01612 1.7e-160 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
OKBOLDLM_01613 2.2e-243 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
OKBOLDLM_01614 3.7e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
OKBOLDLM_01615 0.0 carB 6.3.5.5 F Belongs to the CarB family
OKBOLDLM_01616 3.9e-139 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
OKBOLDLM_01617 4.7e-171 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
OKBOLDLM_01618 7.4e-124 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
OKBOLDLM_01619 2.3e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OKBOLDLM_01620 6.1e-139 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
OKBOLDLM_01621 8e-175 cysP P phosphate transporter
OKBOLDLM_01622 3.6e-221 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
OKBOLDLM_01623 2.1e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
OKBOLDLM_01624 1.4e-139 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
OKBOLDLM_01625 3.2e-136 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
OKBOLDLM_01626 4.3e-75 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
OKBOLDLM_01627 2.2e-266 amyA 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
OKBOLDLM_01628 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
OKBOLDLM_01629 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
OKBOLDLM_01630 2.3e-151 yloC S stress-induced protein
OKBOLDLM_01631 1.5e-40 ylzA S Belongs to the UPF0296 family
OKBOLDLM_01632 8.9e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
OKBOLDLM_01633 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
OKBOLDLM_01634 3.5e-222 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OKBOLDLM_01635 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OKBOLDLM_01636 2.5e-83 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
OKBOLDLM_01637 2.4e-167 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OKBOLDLM_01638 2.6e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OKBOLDLM_01639 1.7e-204 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
OKBOLDLM_01640 7.1e-133 stp 3.1.3.16 T phosphatase
OKBOLDLM_01641 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
OKBOLDLM_01642 3.5e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
OKBOLDLM_01643 2.2e-114 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
OKBOLDLM_01644 1.8e-113 thiN 2.7.6.2 H thiamine pyrophosphokinase
OKBOLDLM_01645 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
OKBOLDLM_01646 6.1e-58 asp S protein conserved in bacteria
OKBOLDLM_01647 1.3e-299 yloV S kinase related to dihydroxyacetone kinase
OKBOLDLM_01648 4.8e-117 sdaAB 4.3.1.17 E L-serine dehydratase
OKBOLDLM_01649 3.9e-154 sdaAA 4.3.1.17 E L-serine dehydratase
OKBOLDLM_01650 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OKBOLDLM_01651 2.2e-91 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
OKBOLDLM_01652 2.3e-176 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
OKBOLDLM_01653 1.9e-167 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
OKBOLDLM_01654 1.1e-127 IQ reductase
OKBOLDLM_01655 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
OKBOLDLM_01656 7.5e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
OKBOLDLM_01657 0.0 smc D Required for chromosome condensation and partitioning
OKBOLDLM_01658 5.9e-172 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
OKBOLDLM_01659 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
OKBOLDLM_01660 9e-232 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OKBOLDLM_01661 9.3e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
OKBOLDLM_01662 1.7e-35 ylqC S Belongs to the UPF0109 family
OKBOLDLM_01663 1.1e-60 ylqD S YlqD protein
OKBOLDLM_01664 1.4e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OKBOLDLM_01665 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
OKBOLDLM_01666 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
OKBOLDLM_01667 5.5e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OKBOLDLM_01668 5.5e-125 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OKBOLDLM_01669 1.4e-266 ylqG
OKBOLDLM_01670 1.6e-42 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
OKBOLDLM_01671 2.6e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
OKBOLDLM_01672 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OKBOLDLM_01673 1.7e-162 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
OKBOLDLM_01674 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OKBOLDLM_01675 5.3e-245 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
OKBOLDLM_01676 3.3e-169 xerC L tyrosine recombinase XerC
OKBOLDLM_01677 2.2e-91 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OKBOLDLM_01678 1.4e-230 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OKBOLDLM_01679 2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
OKBOLDLM_01680 7.8e-51 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
OKBOLDLM_01681 9.9e-74 flgC N Belongs to the flagella basal body rod proteins family
OKBOLDLM_01682 2.5e-31 fliE N Flagellar hook-basal body
OKBOLDLM_01683 2.7e-251 fliF N The M ring may be actively involved in energy transduction
OKBOLDLM_01684 1.4e-176 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
OKBOLDLM_01685 1.4e-85 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
OKBOLDLM_01686 2.7e-241 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
OKBOLDLM_01687 4.5e-71 fliJ N Flagellar biosynthesis chaperone
OKBOLDLM_01688 1.2e-37 ylxF S MgtE intracellular N domain
OKBOLDLM_01689 5.5e-189 fliK N Flagellar hook-length control protein
OKBOLDLM_01690 2.7e-68 flgD N Flagellar basal body rod modification protein
OKBOLDLM_01691 5.4e-136 flgG N Flagellar basal body rod
OKBOLDLM_01692 5.1e-56 fliL N Controls the rotational direction of flagella during chemotaxis
OKBOLDLM_01693 7.8e-180 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
OKBOLDLM_01694 3.8e-175 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OKBOLDLM_01695 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
OKBOLDLM_01696 3.3e-110 fliZ N Flagellar biosynthesis protein, FliO
OKBOLDLM_01697 3.7e-109 fliP N Plays a role in the flagellum-specific transport system
OKBOLDLM_01698 7.5e-37 fliQ N Role in flagellar biosynthesis
OKBOLDLM_01699 3.2e-128 fliR N Flagellar biosynthetic protein FliR
OKBOLDLM_01700 2.5e-187 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OKBOLDLM_01701 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OKBOLDLM_01702 2.9e-156 flhF N Flagellar biosynthesis regulator FlhF
OKBOLDLM_01703 4.3e-153 flhG D Belongs to the ParA family
OKBOLDLM_01704 4.9e-188 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
OKBOLDLM_01705 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
OKBOLDLM_01706 2.5e-80 cheW NT COG0835 Chemotaxis signal transduction protein
OKBOLDLM_01707 7e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
OKBOLDLM_01708 4.3e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
OKBOLDLM_01709 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OKBOLDLM_01710 1.7e-47 ylxL
OKBOLDLM_01711 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
OKBOLDLM_01712 4.5e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OKBOLDLM_01713 1.6e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
OKBOLDLM_01714 2.1e-89 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
OKBOLDLM_01715 1.3e-142 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OKBOLDLM_01716 8.4e-137 cdsA 2.7.7.41 S Belongs to the CDS family
OKBOLDLM_01717 2.3e-212 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
OKBOLDLM_01718 4.2e-231 rasP M zinc metalloprotease
OKBOLDLM_01719 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
OKBOLDLM_01720 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OKBOLDLM_01721 1.9e-80 rimP S Required for maturation of 30S ribosomal subunits
OKBOLDLM_01722 3.5e-205 nusA K Participates in both transcription termination and antitermination
OKBOLDLM_01723 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
OKBOLDLM_01724 1.8e-47 ylxQ J ribosomal protein
OKBOLDLM_01725 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OKBOLDLM_01726 8.6e-44 ylxP S protein conserved in bacteria
OKBOLDLM_01727 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OKBOLDLM_01728 2.4e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OKBOLDLM_01729 1.4e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
OKBOLDLM_01730 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OKBOLDLM_01731 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
OKBOLDLM_01732 7e-178 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
OKBOLDLM_01733 3.7e-232 pepR S Belongs to the peptidase M16 family
OKBOLDLM_01734 2.6e-42 ymxH S YlmC YmxH family
OKBOLDLM_01735 6.3e-157 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
OKBOLDLM_01736 6.3e-54 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
OKBOLDLM_01737 1.9e-159 yokA L Recombinase
OKBOLDLM_01738 6.3e-78 yokF 3.1.31.1 L RNA catabolic process
OKBOLDLM_01739 1.5e-92 G SMI1-KNR4 cell-wall
OKBOLDLM_01740 2.5e-165 V HNH endonuclease
OKBOLDLM_01741 1.4e-288 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
OKBOLDLM_01742 2.2e-52 S SMI1-KNR4 cell-wall
OKBOLDLM_01744 1e-126 yunB S Sporulation protein YunB (Spo_YunB)
OKBOLDLM_01745 1.2e-39 S YolD-like protein
OKBOLDLM_01746 5.5e-223 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OKBOLDLM_01748 3.8e-168 S aspartate phosphatase
OKBOLDLM_01749 9.1e-23 S aspartate phosphatase
OKBOLDLM_01752 6.8e-32 S Bacteriophage holin
OKBOLDLM_01754 6.7e-73 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
OKBOLDLM_01755 2.3e-268 M Pectate lyase superfamily protein
OKBOLDLM_01756 2.6e-93
OKBOLDLM_01757 4.8e-194 S Pfam Transposase IS66
OKBOLDLM_01758 7.2e-85 S Phage tail protein
OKBOLDLM_01759 0.0 S peptidoglycan catabolic process
OKBOLDLM_01760 5.1e-52
OKBOLDLM_01763 2.4e-173 xerH A Belongs to the 'phage' integrase family
OKBOLDLM_01764 1.6e-49
OKBOLDLM_01765 9.4e-54
OKBOLDLM_01766 1.2e-83 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
OKBOLDLM_01767 2.7e-13
OKBOLDLM_01768 9.4e-56 S Domain of unknown function (DUF2479)
OKBOLDLM_01769 3.9e-49
OKBOLDLM_01771 3e-57
OKBOLDLM_01772 2.5e-95
OKBOLDLM_01773 4.1e-84
OKBOLDLM_01774 9.5e-57
OKBOLDLM_01777 4.7e-69
OKBOLDLM_01779 1.5e-38
OKBOLDLM_01780 1.4e-18
OKBOLDLM_01781 1.3e-94
OKBOLDLM_01782 4.6e-75
OKBOLDLM_01788 2.4e-38 L Belongs to the 'phage' integrase family
OKBOLDLM_01789 5.6e-189
OKBOLDLM_01790 1.3e-33
OKBOLDLM_01791 6.9e-12 K Transcriptional regulator
OKBOLDLM_01795 3.4e-40
OKBOLDLM_01796 5.6e-07 S YopX protein
OKBOLDLM_01799 9.8e-23
OKBOLDLM_01803 5.1e-65 2.1.1.294, 2.7.1.181 N bacterial-type flagellum assembly
OKBOLDLM_01805 2.8e-24
OKBOLDLM_01815 3.2e-139 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
OKBOLDLM_01816 2.6e-126 yoqW S Belongs to the SOS response-associated peptidase family
OKBOLDLM_01819 9.9e-08 S YopX protein
OKBOLDLM_01821 9.2e-86 S Pfam:DUF867
OKBOLDLM_01822 2.4e-221 M Parallel beta-helix repeats
OKBOLDLM_01828 2.3e-154
OKBOLDLM_01829 1.6e-166 L AAA domain
OKBOLDLM_01830 1.9e-80
OKBOLDLM_01831 5.3e-273 3.6.4.12 J DnaB-like helicase C terminal domain
OKBOLDLM_01832 1e-204 L DNA primase activity
OKBOLDLM_01833 2.1e-273 recJ L Single-stranded-DNA-specific exonuclease RecJ
OKBOLDLM_01834 0.0 S Bacterial DNA polymerase III alpha subunit
OKBOLDLM_01835 6.6e-24 S protein conserved in bacteria
OKBOLDLM_01838 2.9e-69 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
OKBOLDLM_01839 6.2e-88 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
OKBOLDLM_01840 1e-55 2.1.1.113, 2.1.1.72 L N-4 methylation of cytosine
OKBOLDLM_01841 5e-162 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
OKBOLDLM_01854 7.9e-67 S NrdI Flavodoxin like
OKBOLDLM_01855 2.2e-115 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OKBOLDLM_01856 8e-41 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OKBOLDLM_01857 5.8e-169 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OKBOLDLM_01859 9.1e-104 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OKBOLDLM_01860 2.3e-82 L HNH endonuclease
OKBOLDLM_01861 8.7e-44 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OKBOLDLM_01862 7.2e-26
OKBOLDLM_01863 7.4e-11 O Glutaredoxin
OKBOLDLM_01864 8.8e-72 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
OKBOLDLM_01868 2.9e-96 S Thymidylate synthase
OKBOLDLM_01869 5.7e-13 S nucleic acid binding
OKBOLDLM_01870 3.5e-48 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OKBOLDLM_01871 4.9e-29 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OKBOLDLM_01874 8.2e-88
OKBOLDLM_01878 1.1e-22 sspB S spore protein
OKBOLDLM_01879 3.7e-151 S Calcineurin-like phosphoesterase
OKBOLDLM_01886 4.6e-89 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
OKBOLDLM_01888 3.2e-37 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
OKBOLDLM_01889 1.1e-189 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OKBOLDLM_01890 2.2e-216 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
OKBOLDLM_01891 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OKBOLDLM_01892 4.7e-302 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OKBOLDLM_01893 6.6e-128 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
OKBOLDLM_01894 2.6e-29 S YlzJ-like protein
OKBOLDLM_01895 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
OKBOLDLM_01896 2e-129 ymfC K Transcriptional regulator
OKBOLDLM_01897 6.2e-225 ymfD EGP Major facilitator Superfamily
OKBOLDLM_01898 5.8e-74 K helix_turn_helix multiple antibiotic resistance protein
OKBOLDLM_01899 0.0 ydgH S drug exporters of the RND superfamily
OKBOLDLM_01900 7e-234 ymfF S Peptidase M16
OKBOLDLM_01901 7.3e-239 ymfH S zinc protease
OKBOLDLM_01902 8.1e-126 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
OKBOLDLM_01903 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
OKBOLDLM_01904 5.1e-142 ymfK S Protein of unknown function (DUF3388)
OKBOLDLM_01905 1.4e-119 ymfM S protein conserved in bacteria
OKBOLDLM_01906 4.2e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OKBOLDLM_01907 2.1e-230 cinA 3.5.1.42 S Belongs to the CinA family
OKBOLDLM_01908 7.6e-186 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OKBOLDLM_01909 2.4e-180 pbpX V Beta-lactamase
OKBOLDLM_01910 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
OKBOLDLM_01911 1.9e-152 ymdB S protein conserved in bacteria
OKBOLDLM_01912 1.2e-36 spoVS S Stage V sporulation protein S
OKBOLDLM_01913 3.1e-195 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
OKBOLDLM_01914 7e-212 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
OKBOLDLM_01915 1.1e-294 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OKBOLDLM_01916 1.2e-65 ymcA 3.6.3.21 S Belongs to the UPF0342 family
OKBOLDLM_01917 2.1e-86 cotE S Spore coat protein
OKBOLDLM_01918 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OKBOLDLM_01919 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OKBOLDLM_01920 1.1e-91 pksB 3.1.2.6 S Polyketide biosynthesis
OKBOLDLM_01921 8.6e-159 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
OKBOLDLM_01922 6.9e-173 pksD Q Acyl transferase domain
OKBOLDLM_01923 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
OKBOLDLM_01924 8.5e-35 acpK IQ Phosphopantetheine attachment site
OKBOLDLM_01925 7.7e-241 pksG 2.3.3.10 I synthase
OKBOLDLM_01926 8.8e-139 pksH 4.2.1.18 I enoyl-CoA hydratase
OKBOLDLM_01927 6.8e-136 pksI I Belongs to the enoyl-CoA hydratase isomerase family
OKBOLDLM_01928 0.0 rhiB IQ polyketide synthase
OKBOLDLM_01929 0.0 Q Polyketide synthase of type I
OKBOLDLM_01930 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
OKBOLDLM_01931 0.0 dhbF IQ polyketide synthase
OKBOLDLM_01932 0.0 pks13 HQ Beta-ketoacyl synthase
OKBOLDLM_01933 1.4e-223 cypA C Cytochrome P450
OKBOLDLM_01934 5.2e-72 nucB M Deoxyribonuclease NucA/NucB
OKBOLDLM_01935 3.4e-116 yoaK S Membrane
OKBOLDLM_01936 1.6e-61 ymzB
OKBOLDLM_01937 3.1e-248 aprX O Belongs to the peptidase S8 family
OKBOLDLM_01939 1e-117 ymaC S Replication protein
OKBOLDLM_01940 1.4e-75 ymaD O redox protein, regulator of disulfide bond formation
OKBOLDLM_01941 9.8e-53 ebrB P Small Multidrug Resistance protein
OKBOLDLM_01942 2.5e-47 ebrA P Small Multidrug Resistance protein
OKBOLDLM_01944 2.8e-43 ymaF S YmaF family
OKBOLDLM_01945 6.7e-165 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OKBOLDLM_01946 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
OKBOLDLM_01947 2.6e-40
OKBOLDLM_01948 7.9e-21 ymzA
OKBOLDLM_01949 2.3e-58 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
OKBOLDLM_01950 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OKBOLDLM_01951 2.6e-183 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OKBOLDLM_01952 1.3e-103 ymaB S MutT family
OKBOLDLM_01954 1.2e-87 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OKBOLDLM_01955 8.6e-176 spoVK O stage V sporulation protein K
OKBOLDLM_01956 3.7e-227 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OKBOLDLM_01957 5e-240 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
OKBOLDLM_01958 8.8e-66 glnR K transcriptional
OKBOLDLM_01959 1.2e-260 glnA 6.3.1.2 E glutamine synthetase
OKBOLDLM_01961 1.3e-12
OKBOLDLM_01962 3.9e-116 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
OKBOLDLM_01963 8.6e-213 cypA C Cytochrome P450
OKBOLDLM_01964 5.1e-246 xynT G MFS/sugar transport protein
OKBOLDLM_01965 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
OKBOLDLM_01966 9.6e-206 xylR GK ROK family
OKBOLDLM_01967 2.2e-254 xylA 5.3.1.5 G Belongs to the xylose isomerase family
OKBOLDLM_01968 1.8e-273 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
OKBOLDLM_01969 1.5e-116 3.2.1.8 G Glycosyl hydrolases family 11
OKBOLDLM_01970 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
OKBOLDLM_01971 1.3e-88 K Transcriptional regulator, TetR family
OKBOLDLM_01972 1.2e-175 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
OKBOLDLM_01974 2.5e-195 S aspartate phosphatase
OKBOLDLM_01976 0.0 L Transposase and inactivated derivatives, TnpA family
OKBOLDLM_01977 7.1e-85 L resolvase
OKBOLDLM_01978 1.3e-78
OKBOLDLM_01980 6e-26 S Protein of unknown function (DUF1657)
OKBOLDLM_01981 4.1e-78 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OKBOLDLM_01982 2.6e-80 spoVAC S stage V sporulation protein AC
OKBOLDLM_01983 1e-195 spoVAD I Stage V sporulation protein AD
OKBOLDLM_01984 8.5e-57 spoVAE S stage V sporulation protein
OKBOLDLM_01985 5.8e-29 S Protein of unknown function (DUF1657)
OKBOLDLM_01986 2.1e-149 yetF1 S membrane
OKBOLDLM_01987 1.2e-70 S Protein of unknown function (DUF421)
OKBOLDLM_01988 2.7e-285 clsA_1 I PLD-like domain
OKBOLDLM_01989 2.5e-92 S Protein of unknown function (DUF421)
OKBOLDLM_01991 1.7e-66 S DinB family
OKBOLDLM_01992 8.5e-182 adhP 1.1.1.1 C alcohol dehydrogenase
OKBOLDLM_01993 4e-11
OKBOLDLM_01995 2.9e-26 S Protein of unknown function (DUF4025)
OKBOLDLM_01996 1.1e-10 ywlA S Uncharacterised protein family (UPF0715)
OKBOLDLM_01997 1.1e-128 yoaP 3.1.3.18 K YoaP-like
OKBOLDLM_01998 1.1e-90 J Acetyltransferase (GNAT) domain
OKBOLDLM_02000 1.4e-34
OKBOLDLM_02002 6.6e-100 ynaE S Domain of unknown function (DUF3885)
OKBOLDLM_02003 1.4e-187 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OKBOLDLM_02004 1.1e-115 AA10,CBM73 S Pfam:Chitin_bind_3
OKBOLDLM_02006 3.3e-84 yvgO
OKBOLDLM_02008 0.0 yobO M Pectate lyase superfamily protein
OKBOLDLM_02009 1.3e-32 S TM2 domain
OKBOLDLM_02010 1.7e-75 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
OKBOLDLM_02011 9.7e-128 yndL S Replication protein
OKBOLDLM_02013 2e-136 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
OKBOLDLM_02014 5.8e-66 yndM S Protein of unknown function (DUF2512)
OKBOLDLM_02015 1.3e-11 yoaW
OKBOLDLM_02016 9e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OKBOLDLM_02017 1.2e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
OKBOLDLM_02018 1.6e-109 yneB L resolvase
OKBOLDLM_02019 9.8e-33 ynzC S UPF0291 protein
OKBOLDLM_02020 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OKBOLDLM_02021 7.7e-79 yneE S Sporulation inhibitor of replication protein sirA
OKBOLDLM_02022 2.3e-28 yneF S UPF0154 protein
OKBOLDLM_02023 8.9e-23 ynzD S Spo0E like sporulation regulatory protein
OKBOLDLM_02024 1.2e-121 ccdA O cytochrome c biogenesis protein
OKBOLDLM_02025 1.2e-56 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
OKBOLDLM_02026 5.6e-75 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
OKBOLDLM_02027 2.8e-70 yneK S Protein of unknown function (DUF2621)
OKBOLDLM_02028 5.7e-59 hspX O Spore coat protein
OKBOLDLM_02029 2.3e-19 sspP S Belongs to the SspP family
OKBOLDLM_02030 7.5e-15 sspO S Belongs to the SspO family
OKBOLDLM_02031 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OKBOLDLM_02032 3.6e-88 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OKBOLDLM_02034 1.1e-31 tlp S Belongs to the Tlp family
OKBOLDLM_02035 7.7e-73 yneP S Thioesterase-like superfamily
OKBOLDLM_02036 1.9e-49 yneQ
OKBOLDLM_02037 3.4e-43 yneR S Belongs to the HesB IscA family
OKBOLDLM_02038 4.2e-93 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
OKBOLDLM_02039 3.3e-68 yccU S CoA-binding protein
OKBOLDLM_02040 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
OKBOLDLM_02041 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
OKBOLDLM_02042 4.6e-13
OKBOLDLM_02043 1.2e-39 ynfC
OKBOLDLM_02044 4e-246 agcS E Sodium alanine symporter
OKBOLDLM_02045 5.2e-22 yndG S DoxX-like family
OKBOLDLM_02046 2e-77 yndH S Domain of unknown function (DUF4166)
OKBOLDLM_02047 4.6e-275 yndJ S YndJ-like protein
OKBOLDLM_02048 1.2e-49 S Domain of unknown function (DUF4870)
OKBOLDLM_02049 3.2e-216 T PhoQ Sensor
OKBOLDLM_02050 9e-122 T Transcriptional regulatory protein, C terminal
OKBOLDLM_02051 6.5e-240 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
OKBOLDLM_02052 1.5e-278 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
OKBOLDLM_02053 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OKBOLDLM_02054 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OKBOLDLM_02055 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OKBOLDLM_02056 4.5e-206 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
OKBOLDLM_02057 2e-122 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
OKBOLDLM_02058 5.4e-105 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
OKBOLDLM_02059 2.3e-114 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OKBOLDLM_02060 7.2e-164 bioI 1.14.14.46 C Cytochrome P450
OKBOLDLM_02061 8.5e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OKBOLDLM_02062 4e-122 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
OKBOLDLM_02063 3.9e-199 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
OKBOLDLM_02064 1.6e-252 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
OKBOLDLM_02065 8.5e-134 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
OKBOLDLM_02066 1.6e-67 yngA S membrane
OKBOLDLM_02067 8.6e-154 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
OKBOLDLM_02068 1.6e-103 yngC S SNARE associated Golgi protein
OKBOLDLM_02069 1.1e-286 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
OKBOLDLM_02070 3.6e-132 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
OKBOLDLM_02071 2.4e-164 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
OKBOLDLM_02072 1.2e-29 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
OKBOLDLM_02073 7.7e-239 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
OKBOLDLM_02074 2.3e-311 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OKBOLDLM_02075 1.5e-206 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
OKBOLDLM_02076 1.6e-293 yngK T Glycosyl hydrolase-like 10
OKBOLDLM_02077 1.9e-62 yngL S Protein of unknown function (DUF1360)
OKBOLDLM_02078 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
OKBOLDLM_02079 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OKBOLDLM_02080 6.5e-292 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OKBOLDLM_02081 6.8e-257 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
OKBOLDLM_02082 3.4e-180 yoxA 5.1.3.3 G Aldose 1-epimerase
OKBOLDLM_02083 9.9e-242 yoeA V MATE efflux family protein
OKBOLDLM_02084 6.1e-94 yoeB S IseA DL-endopeptidase inhibitor
OKBOLDLM_02086 1.1e-33 yoeD G Helix-turn-helix domain
OKBOLDLM_02087 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
OKBOLDLM_02088 1.1e-188 ybcL EGP Major facilitator Superfamily
OKBOLDLM_02089 6.7e-50 ybzH K Helix-turn-helix domain
OKBOLDLM_02090 1.1e-270 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OKBOLDLM_02091 3.6e-290 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
OKBOLDLM_02092 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
OKBOLDLM_02093 3.6e-147 gltC K Transcriptional regulator
OKBOLDLM_02094 5.1e-196 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OKBOLDLM_02095 6.1e-135 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OKBOLDLM_02096 3.6e-61 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
OKBOLDLM_02097 6.9e-122 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
OKBOLDLM_02098 1.3e-37 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
OKBOLDLM_02099 1.7e-115 yoxB
OKBOLDLM_02100 2.2e-194 yoaB EGP Major facilitator Superfamily
OKBOLDLM_02101 1.2e-264 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
OKBOLDLM_02102 1.5e-186 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OKBOLDLM_02103 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OKBOLDLM_02104 5.7e-27 yoaF
OKBOLDLM_02106 1.1e-93 hpr K helix_turn_helix multiple antibiotic resistance protein
OKBOLDLM_02107 1.1e-28
OKBOLDLM_02110 4.6e-52 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
OKBOLDLM_02111 3.4e-121 yobQ K helix_turn_helix, arabinose operon control protein
OKBOLDLM_02112 7e-85 yobS K Transcriptional regulator
OKBOLDLM_02113 8.8e-125 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
OKBOLDLM_02114 3.9e-87 yobW
OKBOLDLM_02115 7.6e-55 czrA K transcriptional
OKBOLDLM_02116 3.3e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
OKBOLDLM_02117 1.4e-90 yozB S membrane
OKBOLDLM_02118 1.9e-133 yocB J Protein required for attachment to host cells
OKBOLDLM_02119 3.4e-91 yocC
OKBOLDLM_02120 5.3e-181 yocD 3.4.17.13 V peptidase S66
OKBOLDLM_02122 2.1e-112 yocH CBM50 M COG1388 FOG LysM repeat
OKBOLDLM_02123 0.0 recQ 3.6.4.12 L DNA helicase
OKBOLDLM_02125 1.1e-110 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OKBOLDLM_02126 2e-56 dksA T general stress protein
OKBOLDLM_02127 6.3e-10 yocL
OKBOLDLM_02128 9.8e-09
OKBOLDLM_02129 3.7e-87 yocM O Belongs to the small heat shock protein (HSP20) family
OKBOLDLM_02130 7.5e-29 yozN
OKBOLDLM_02131 5.5e-36 yocN
OKBOLDLM_02132 2.4e-56 yozO S Bacterial PH domain
OKBOLDLM_02134 1.6e-31 yozC
OKBOLDLM_02135 5.1e-284 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
OKBOLDLM_02136 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
OKBOLDLM_02137 8.1e-162 sodA 1.15.1.1 P Superoxide dismutase
OKBOLDLM_02138 7.1e-229 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
OKBOLDLM_02139 1.8e-157 yocS S -transporter
OKBOLDLM_02140 8e-123 S Metallo-beta-lactamase superfamily
OKBOLDLM_02141 2.9e-184 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
OKBOLDLM_02142 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
OKBOLDLM_02143 0.0 yojO P Von Willebrand factor
OKBOLDLM_02144 6.5e-162 yojN S ATPase family associated with various cellular activities (AAA)
OKBOLDLM_02145 1.2e-98 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OKBOLDLM_02146 4.5e-161 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
OKBOLDLM_02147 7.8e-35 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
OKBOLDLM_02148 1.9e-217 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
OKBOLDLM_02149 2.3e-105 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OKBOLDLM_02151 1.1e-232 norM V Multidrug efflux pump
OKBOLDLM_02152 6.2e-146 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OKBOLDLM_02153 9.6e-126 yojG S deacetylase
OKBOLDLM_02154 3.7e-60 yojF S Protein of unknown function (DUF1806)
OKBOLDLM_02155 6.4e-23
OKBOLDLM_02156 2.6e-158 rarD S -transporter
OKBOLDLM_02157 8.9e-78 yozR S COG0071 Molecular chaperone (small heat shock protein)
OKBOLDLM_02159 6.8e-63 yodA S tautomerase
OKBOLDLM_02160 3.5e-52 yodB K transcriptional
OKBOLDLM_02161 2.8e-103 yodC C nitroreductase
OKBOLDLM_02162 5.3e-107 mhqD S Carboxylesterase
OKBOLDLM_02163 2.2e-168 yodE E COG0346 Lactoylglutathione lyase and related lyases
OKBOLDLM_02164 3.1e-19 S Protein of unknown function (DUF3311)
OKBOLDLM_02165 3.2e-262 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OKBOLDLM_02166 4.3e-267 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
OKBOLDLM_02167 1.6e-282 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OKBOLDLM_02168 3.8e-128 yydK K Transcriptional regulator
OKBOLDLM_02169 5.5e-248 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
OKBOLDLM_02170 1.9e-119 yodH Q Methyltransferase
OKBOLDLM_02171 1e-19 yodI
OKBOLDLM_02172 7.6e-141 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
OKBOLDLM_02173 7.7e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
OKBOLDLM_02175 3.3e-55 yodL S YodL-like
OKBOLDLM_02176 4.4e-101 yodM 3.6.1.27 I Acid phosphatase homologues
OKBOLDLM_02177 1.8e-23 yozD S YozD-like protein
OKBOLDLM_02179 5.6e-121 yodN
OKBOLDLM_02180 6.1e-51 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OKBOLDLM_02181 3.4e-35 yozE S Belongs to the UPF0346 family
OKBOLDLM_02182 1.1e-43 yokU S YokU-like protein, putative antitoxin
OKBOLDLM_02183 1.2e-274 kamA 5.4.3.2 E lysine 2,3-aminomutase
OKBOLDLM_02184 1.4e-140 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
OKBOLDLM_02185 1e-248 yodQ 3.5.1.16 E Acetylornithine deacetylase
OKBOLDLM_02186 2.7e-118 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
OKBOLDLM_02187 1.5e-121 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OKBOLDLM_02188 3e-235 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OKBOLDLM_02190 5.4e-64 yosT L Bacterial transcription activator, effector binding domain
OKBOLDLM_02192 1.3e-137 yiiD K acetyltransferase
OKBOLDLM_02193 7e-226 cgeD M maturation of the outermost layer of the spore
OKBOLDLM_02194 1.4e-36 cgeC
OKBOLDLM_02195 3.1e-48 cgeA
OKBOLDLM_02196 7.7e-169 cgeB S Spore maturation protein
OKBOLDLM_02197 3.7e-210 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
OKBOLDLM_02198 1.2e-69 4.2.1.115 GM Polysaccharide biosynthesis protein
OKBOLDLM_02201 1.9e-121 lldD 1.13.12.4 C FMN-dependent dehydrogenase
OKBOLDLM_02203 1.9e-13 S Regulatory protein YrvL
OKBOLDLM_02204 6.4e-211 yokA L Recombinase
OKBOLDLM_02205 1.2e-100 4.2.1.115 GM Polysaccharide biosynthesis protein
OKBOLDLM_02206 6.4e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
OKBOLDLM_02207 4.3e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OKBOLDLM_02208 8.9e-66 ypoP K transcriptional
OKBOLDLM_02209 1.7e-94 ypmS S protein conserved in bacteria
OKBOLDLM_02210 9.5e-130 ypmR E GDSL-like Lipase/Acylhydrolase
OKBOLDLM_02211 2e-103 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
OKBOLDLM_02212 7.5e-39 ypmP S Protein of unknown function (DUF2535)
OKBOLDLM_02213 1.3e-240 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OKBOLDLM_02214 3.8e-163 pspF K Transcriptional regulator
OKBOLDLM_02215 6.6e-108 hlyIII S protein, Hemolysin III
OKBOLDLM_02216 1.7e-108 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
OKBOLDLM_02217 7.8e-85 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OKBOLDLM_02218 2.8e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OKBOLDLM_02219 3e-110 ypjP S YpjP-like protein
OKBOLDLM_02220 2.9e-126 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
OKBOLDLM_02221 1.7e-75 yphP S Belongs to the UPF0403 family
OKBOLDLM_02222 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
OKBOLDLM_02223 6e-152 ypgR C COG0694 Thioredoxin-like proteins and domains
OKBOLDLM_02224 2.3e-89 ypgQ S phosphohydrolase
OKBOLDLM_02225 2.1e-82 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
OKBOLDLM_02227 2.8e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OKBOLDLM_02228 3e-212 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
OKBOLDLM_02229 1e-30 cspD K Cold-shock protein
OKBOLDLM_02230 6.3e-11 degR
OKBOLDLM_02231 2.3e-35 S Protein of unknown function (DUF2564)
OKBOLDLM_02232 3.7e-27 ypeQ S Zinc-finger
OKBOLDLM_02233 2e-118 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
OKBOLDLM_02234 5.2e-119 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OKBOLDLM_02235 7.1e-68 rnhA 3.1.26.4 L Ribonuclease
OKBOLDLM_02237 8e-160 polA 2.7.7.7 L 5'3' exonuclease
OKBOLDLM_02239 3.7e-33 ypbS S Protein of unknown function (DUF2533)
OKBOLDLM_02240 0.0 ypbR S Dynamin family
OKBOLDLM_02241 4.8e-85 ypbQ S protein conserved in bacteria
OKBOLDLM_02242 1.2e-194 bcsA Q Naringenin-chalcone synthase
OKBOLDLM_02243 2e-101 J Acetyltransferase (GNAT) domain
OKBOLDLM_02244 6.6e-45 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
OKBOLDLM_02245 2.4e-07 S Bacillus cereus group antimicrobial protein
OKBOLDLM_02246 5.1e-232 pbuX F xanthine
OKBOLDLM_02247 2.9e-94 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
OKBOLDLM_02248 5.4e-127 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
OKBOLDLM_02249 3.9e-148 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
OKBOLDLM_02250 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
OKBOLDLM_02252 6.6e-22 S YpzG-like protein
OKBOLDLM_02253 2e-74 yqgA
OKBOLDLM_02254 1.3e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
OKBOLDLM_02255 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
OKBOLDLM_02256 5.9e-97 ypsA S Belongs to the UPF0398 family
OKBOLDLM_02257 5.6e-23 cotD S Inner spore coat protein D
OKBOLDLM_02259 7.5e-225 yprB L RNase_H superfamily
OKBOLDLM_02260 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
OKBOLDLM_02261 1.3e-87 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
OKBOLDLM_02262 4.4e-60 hspX O Belongs to the small heat shock protein (HSP20) family
OKBOLDLM_02263 1.5e-38 yppG S YppG-like protein
OKBOLDLM_02265 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
OKBOLDLM_02268 9.2e-178 yppC S Protein of unknown function (DUF2515)
OKBOLDLM_02269 1.2e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
OKBOLDLM_02270 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
OKBOLDLM_02271 1.4e-86 ypoC
OKBOLDLM_02272 7.8e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OKBOLDLM_02273 3.4e-129 dnaD L DNA replication protein DnaD
OKBOLDLM_02274 7.1e-250 asnS 6.1.1.22 J asparaginyl-tRNA
OKBOLDLM_02275 5e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
OKBOLDLM_02276 1.4e-73 ypmB S protein conserved in bacteria
OKBOLDLM_02277 6.7e-23 ypmA S Protein of unknown function (DUF4264)
OKBOLDLM_02278 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
OKBOLDLM_02279 3.9e-63 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OKBOLDLM_02280 1.2e-152 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OKBOLDLM_02281 2e-149 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
OKBOLDLM_02282 4.9e-179 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
OKBOLDLM_02283 9.5e-209 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
OKBOLDLM_02284 4.5e-208 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
OKBOLDLM_02285 1e-125 bshB1 S proteins, LmbE homologs
OKBOLDLM_02286 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
OKBOLDLM_02287 3.8e-145 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
OKBOLDLM_02288 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
OKBOLDLM_02289 4.7e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
OKBOLDLM_02290 2.5e-222 oxdC 4.1.1.2 G Oxalate decarboxylase
OKBOLDLM_02291 1.5e-138 ypjB S sporulation protein
OKBOLDLM_02292 5.2e-99 ypjA S membrane
OKBOLDLM_02293 5.7e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
OKBOLDLM_02294 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
OKBOLDLM_02295 2.5e-94 qcrA C Menaquinol-cytochrome c reductase
OKBOLDLM_02296 8.3e-73 ypiF S Protein of unknown function (DUF2487)
OKBOLDLM_02297 8.1e-99 ypiB S Belongs to the UPF0302 family
OKBOLDLM_02298 1.5e-228 S COG0457 FOG TPR repeat
OKBOLDLM_02299 1.3e-227 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
OKBOLDLM_02300 1.8e-201 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
OKBOLDLM_02301 3.1e-198 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OKBOLDLM_02302 5.5e-136 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
OKBOLDLM_02303 5.6e-225 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
OKBOLDLM_02304 3.3e-110 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
OKBOLDLM_02305 3e-123 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
OKBOLDLM_02306 6.3e-153 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OKBOLDLM_02307 5.8e-283 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OKBOLDLM_02308 1.7e-58 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
OKBOLDLM_02309 6.3e-199 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OKBOLDLM_02310 2.3e-215 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OKBOLDLM_02311 7.4e-138 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
OKBOLDLM_02312 2.2e-78 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
OKBOLDLM_02313 4.8e-196 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
OKBOLDLM_02314 1.5e-129 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
OKBOLDLM_02315 1.5e-135 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
OKBOLDLM_02316 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
OKBOLDLM_02317 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
OKBOLDLM_02318 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
OKBOLDLM_02319 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OKBOLDLM_02320 1.3e-10 yphF
OKBOLDLM_02321 7.1e-130 yphF
OKBOLDLM_02322 1.5e-16 yphE S Protein of unknown function (DUF2768)
OKBOLDLM_02323 5.2e-187 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
OKBOLDLM_02324 1.8e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
OKBOLDLM_02325 2.4e-99 yphA
OKBOLDLM_02326 4.7e-08 S YpzI-like protein
OKBOLDLM_02327 1.5e-178 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
OKBOLDLM_02328 2.1e-205 rpsA 1.17.7.4 J Ribosomal protein S1
OKBOLDLM_02329 7.5e-110 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
OKBOLDLM_02330 2.5e-12 S Family of unknown function (DUF5359)
OKBOLDLM_02331 1.1e-57 ypfA M Flagellar protein YcgR
OKBOLDLM_02332 2.5e-245 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
OKBOLDLM_02333 4.7e-149 sleB 3.5.1.28 M Spore cortex-lytic enzyme
OKBOLDLM_02334 1.6e-120 prsW S Involved in the degradation of specific anti-sigma factors
OKBOLDLM_02335 7.2e-186 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
OKBOLDLM_02336 2e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
OKBOLDLM_02337 2.2e-105 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
OKBOLDLM_02338 1.9e-141 ypbG S Calcineurin-like phosphoesterase superfamily domain
OKBOLDLM_02339 1.1e-83 ypbF S Protein of unknown function (DUF2663)
OKBOLDLM_02340 2.5e-80 ypbD S metal-dependent membrane protease
OKBOLDLM_02341 2.5e-275 recQ 3.6.4.12 L DNA helicase
OKBOLDLM_02342 1.5e-189 ypbB 5.1.3.1 S protein conserved in bacteria
OKBOLDLM_02343 3.6e-41 fer C Ferredoxin
OKBOLDLM_02344 1.6e-92 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
OKBOLDLM_02345 2.2e-290 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OKBOLDLM_02346 3.1e-169 rsiX
OKBOLDLM_02347 2.2e-102 sigX K Belongs to the sigma-70 factor family. ECF subfamily
OKBOLDLM_02348 0.0 resE 2.7.13.3 T Histidine kinase
OKBOLDLM_02349 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OKBOLDLM_02350 1.5e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
OKBOLDLM_02351 1.1e-308 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
OKBOLDLM_02352 3.4e-97 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
OKBOLDLM_02353 6.4e-131 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
OKBOLDLM_02354 3.8e-88 spmB S Spore maturation protein
OKBOLDLM_02355 1.3e-102 spmA S Spore maturation protein
OKBOLDLM_02356 1.1e-209 dacB 3.4.16.4 M Belongs to the peptidase S11 family
OKBOLDLM_02357 8.1e-82 ypuI S Protein of unknown function (DUF3907)
OKBOLDLM_02358 5.1e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OKBOLDLM_02359 3.1e-128 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OKBOLDLM_02361 6.2e-88 ypuF S Domain of unknown function (DUF309)
OKBOLDLM_02362 1e-63 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OKBOLDLM_02363 5.6e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
OKBOLDLM_02364 2.3e-226 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OKBOLDLM_02365 7.2e-110 ribE 2.5.1.9 H Riboflavin synthase
OKBOLDLM_02366 6.2e-202 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OKBOLDLM_02367 5.1e-46 ypuD
OKBOLDLM_02368 3.9e-96 sipT 3.4.21.89 U Belongs to the peptidase S26 family
OKBOLDLM_02369 8.5e-79 ccdC1 O Protein of unknown function (DUF1453)
OKBOLDLM_02370 5.7e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OKBOLDLM_02371 2.6e-150 ypuA S Secreted protein
OKBOLDLM_02372 6.5e-251 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
OKBOLDLM_02373 6.2e-266 spoVAF EG Stage V sporulation protein AF
OKBOLDLM_02374 2.4e-107 spoVAEA S stage V sporulation protein
OKBOLDLM_02375 2.5e-56 spoVAEB S stage V sporulation protein
OKBOLDLM_02376 3.5e-188 spoVAD I Stage V sporulation protein AD
OKBOLDLM_02377 1.3e-78 spoVAC S stage V sporulation protein AC
OKBOLDLM_02378 4.5e-68 spoVAB S Stage V sporulation protein AB
OKBOLDLM_02379 1.5e-109 spoVAA S Stage V sporulation protein AA
OKBOLDLM_02380 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OKBOLDLM_02381 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
OKBOLDLM_02382 2.3e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
OKBOLDLM_02383 5.9e-211 dacF 3.4.16.4 M Belongs to the peptidase S11 family
OKBOLDLM_02384 4.2e-147 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
OKBOLDLM_02385 2.7e-227 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
OKBOLDLM_02386 2.7e-163 xerD L recombinase XerD
OKBOLDLM_02387 6.4e-37 S Protein of unknown function (DUF4227)
OKBOLDLM_02388 2.7e-79 fur P Belongs to the Fur family
OKBOLDLM_02389 2.7e-109 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
OKBOLDLM_02390 8.1e-32 yqkK
OKBOLDLM_02391 3e-23
OKBOLDLM_02392 3.6e-241 mleA 1.1.1.38 C malic enzyme
OKBOLDLM_02393 1.9e-240 mleN C Na H antiporter
OKBOLDLM_02394 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
OKBOLDLM_02395 1.2e-183 ansA 3.5.1.1 EJ L-asparaginase
OKBOLDLM_02396 5e-57 ansR K Transcriptional regulator
OKBOLDLM_02397 2.5e-214 yqxK 3.6.4.12 L DNA helicase
OKBOLDLM_02398 9e-93 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
OKBOLDLM_02400 1.2e-163 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
OKBOLDLM_02402 3.4e-166 yqkD S COG1073 Hydrolases of the alpha beta superfamily
OKBOLDLM_02403 3.2e-39 yqkC S Protein of unknown function (DUF2552)
OKBOLDLM_02404 1.6e-58 yqkB S Belongs to the HesB IscA family
OKBOLDLM_02405 9e-165 yqkA K GrpB protein
OKBOLDLM_02407 2.8e-87 yqjY K acetyltransferase
OKBOLDLM_02408 5.7e-233 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OKBOLDLM_02409 9.3e-56 S YolD-like protein
OKBOLDLM_02411 1.8e-145 yueF S transporter activity
OKBOLDLM_02413 5e-176 coaA 2.7.1.33 F Pantothenic acid kinase
OKBOLDLM_02414 2.1e-111 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
OKBOLDLM_02415 1.5e-119 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
OKBOLDLM_02416 1.8e-136 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
OKBOLDLM_02417 2.3e-168 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
OKBOLDLM_02418 7.9e-141 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OKBOLDLM_02419 1.8e-156 K LysR substrate binding domain
OKBOLDLM_02420 1.6e-46 S GlpM protein
OKBOLDLM_02421 8.2e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
OKBOLDLM_02422 4.5e-143 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
OKBOLDLM_02423 4e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
OKBOLDLM_02424 2.8e-168 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
OKBOLDLM_02425 7.7e-285 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OKBOLDLM_02426 1.3e-265 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OKBOLDLM_02427 9.4e-231 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OKBOLDLM_02428 7.4e-27 yqzJ
OKBOLDLM_02429 2.1e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
OKBOLDLM_02430 1.2e-200 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
OKBOLDLM_02431 3e-284 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
OKBOLDLM_02432 2e-71 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
OKBOLDLM_02434 3.6e-91 yqjB S protein conserved in bacteria
OKBOLDLM_02435 7.7e-169 yqjA S Putative aromatic acid exporter C-terminal domain
OKBOLDLM_02436 5.2e-125 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OKBOLDLM_02437 1.1e-105 artQ E COG0765 ABC-type amino acid transport system, permease component
OKBOLDLM_02438 9.4e-133 artP ET Belongs to the bacterial solute-binding protein 3 family
OKBOLDLM_02439 1e-75 yqiW S Belongs to the UPF0403 family
OKBOLDLM_02440 1.6e-168 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
OKBOLDLM_02441 3.5e-193 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OKBOLDLM_02442 6.7e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
OKBOLDLM_02443 7.8e-164 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
OKBOLDLM_02444 5.7e-261 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
OKBOLDLM_02445 2e-205 buk 2.7.2.7 C Belongs to the acetokinase family
OKBOLDLM_02446 2.6e-205 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
OKBOLDLM_02447 1.3e-149 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
OKBOLDLM_02448 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
OKBOLDLM_02449 2.7e-33 yqzF S Protein of unknown function (DUF2627)
OKBOLDLM_02450 7.1e-156 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
OKBOLDLM_02451 7.8e-266 prpD 4.2.1.79 S 2-methylcitrate dehydratase
OKBOLDLM_02452 3.5e-205 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
OKBOLDLM_02453 2.5e-86 mmgC I acyl-CoA dehydrogenase
OKBOLDLM_02454 1.9e-99 mmgC I acyl-CoA dehydrogenase
OKBOLDLM_02455 1.3e-143 hbdA 1.1.1.157 I Dehydrogenase
OKBOLDLM_02456 2.7e-208 mmgA 2.3.1.9 I Belongs to the thiolase family
OKBOLDLM_02457 9.6e-127 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
OKBOLDLM_02458 1.4e-97 amiC 3.5.1.28 M Cell wall hydrolase autolysin
OKBOLDLM_02459 5.7e-17
OKBOLDLM_02460 2.3e-92 ytaF P Probably functions as a manganese efflux pump
OKBOLDLM_02461 3.7e-111 K Protein of unknown function (DUF1232)
OKBOLDLM_02463 2.2e-207 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
OKBOLDLM_02466 2.9e-202 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OKBOLDLM_02468 2.7e-143 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
OKBOLDLM_02469 3.2e-234 rseP 3.4.21.116 M Stage IV sporulation protein B
OKBOLDLM_02470 6.2e-310 recN L May be involved in recombinational repair of damaged DNA
OKBOLDLM_02471 4.3e-77 argR K Regulates arginine biosynthesis genes
OKBOLDLM_02472 9.9e-152 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
OKBOLDLM_02473 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OKBOLDLM_02474 7e-156 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
OKBOLDLM_02475 1.3e-38 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
OKBOLDLM_02476 2.5e-242 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
OKBOLDLM_02477 5.7e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OKBOLDLM_02478 9.5e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OKBOLDLM_02479 1.4e-66 yqhY S protein conserved in bacteria
OKBOLDLM_02480 8.4e-254 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
OKBOLDLM_02481 4.9e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
OKBOLDLM_02482 1.3e-58 spoIIIAH S SpoIIIAH-like protein
OKBOLDLM_02483 1.4e-114 spoIIIAG S stage III sporulation protein AG
OKBOLDLM_02484 2.9e-100 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
OKBOLDLM_02485 4.1e-199 spoIIIAE S stage III sporulation protein AE
OKBOLDLM_02486 3.3e-41 spoIIIAD S Stage III sporulation protein AD
OKBOLDLM_02487 7.6e-29 spoIIIAC S stage III sporulation protein AC
OKBOLDLM_02488 1e-82 spoIIIAB S Stage III sporulation protein
OKBOLDLM_02489 1.7e-165 spoIIIAA S stage III sporulation protein AA
OKBOLDLM_02490 6.7e-36 yqhV S Protein of unknown function (DUF2619)
OKBOLDLM_02491 2.1e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OKBOLDLM_02492 5.9e-170 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
OKBOLDLM_02493 1.1e-84 yqhR S Conserved membrane protein YqhR
OKBOLDLM_02494 2e-169 yqhQ S Protein of unknown function (DUF1385)
OKBOLDLM_02495 1.2e-59 yqhP
OKBOLDLM_02496 5.1e-159 yqhO S esterase of the alpha-beta hydrolase superfamily
OKBOLDLM_02497 4.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
OKBOLDLM_02498 4.1e-158 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
OKBOLDLM_02499 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
OKBOLDLM_02500 3.6e-282 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OKBOLDLM_02501 1.2e-247 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OKBOLDLM_02502 5.7e-200 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
OKBOLDLM_02503 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
OKBOLDLM_02504 3e-150 yqhG S Bacterial protein YqhG of unknown function
OKBOLDLM_02505 1.7e-21 sinI S Anti-repressor SinI
OKBOLDLM_02506 3.9e-54 sinR K transcriptional
OKBOLDLM_02507 1.5e-138 tasA S Cell division protein FtsN
OKBOLDLM_02508 5.2e-67 sipW 3.4.21.89 U Signal peptidase
OKBOLDLM_02509 3.6e-112 yqxM
OKBOLDLM_02510 1.1e-53 yqzG S Protein of unknown function (DUF3889)
OKBOLDLM_02511 1.5e-25 yqzE S YqzE-like protein
OKBOLDLM_02512 5.4e-57 S ComG operon protein 7
OKBOLDLM_02513 4.1e-21 comGF U Putative Competence protein ComGF
OKBOLDLM_02514 1.2e-20 comGE
OKBOLDLM_02515 6.4e-70 gspH NU Tfp pilus assembly protein FimT
OKBOLDLM_02516 1.3e-48 comGC U Required for transformation and DNA binding
OKBOLDLM_02517 4e-179 comGB NU COG1459 Type II secretory pathway, component PulF
OKBOLDLM_02518 8.9e-198 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OKBOLDLM_02519 6.7e-181 corA P Mg2 transporter protein
OKBOLDLM_02520 1.5e-231 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
OKBOLDLM_02521 8.8e-137 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OKBOLDLM_02523 1.9e-62 yqgZ 1.20.4.1 P Belongs to the ArsC family
OKBOLDLM_02524 3.1e-37 yqgY S Protein of unknown function (DUF2626)
OKBOLDLM_02525 3.6e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
OKBOLDLM_02526 5.4e-20 yqgW S Protein of unknown function (DUF2759)
OKBOLDLM_02527 1.7e-48 yqgV S Thiamine-binding protein
OKBOLDLM_02528 5.7e-39 yqgU
OKBOLDLM_02529 3.7e-126 yqgU
OKBOLDLM_02530 5.3e-201 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
OKBOLDLM_02531 1.8e-178 glcK 2.7.1.2 G Glucokinase
OKBOLDLM_02532 1.6e-27 yqgQ S Protein conserved in bacteria
OKBOLDLM_02533 4.8e-203 nhaC C Na H antiporter
OKBOLDLM_02534 4e-07 yqgO
OKBOLDLM_02535 6e-89 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OKBOLDLM_02536 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
OKBOLDLM_02537 1.2e-50 yqzD
OKBOLDLM_02538 1.3e-73 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OKBOLDLM_02539 6.4e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
OKBOLDLM_02540 2.2e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
OKBOLDLM_02541 8.5e-154 pstA P Phosphate transport system permease
OKBOLDLM_02542 6.8e-154 pstC P probably responsible for the translocation of the substrate across the membrane
OKBOLDLM_02543 2.3e-154 pstS P Phosphate
OKBOLDLM_02544 0.0 pbpA 3.4.16.4 M penicillin-binding protein
OKBOLDLM_02545 3.3e-223 yqgE EGP Major facilitator superfamily
OKBOLDLM_02546 5.3e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
OKBOLDLM_02547 4.2e-70 yqgC S protein conserved in bacteria
OKBOLDLM_02548 2.4e-128 yqgB S Protein of unknown function (DUF1189)
OKBOLDLM_02549 4.2e-44 yqfZ M LysM domain
OKBOLDLM_02550 5e-199 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OKBOLDLM_02551 6.7e-52 yqfX S membrane
OKBOLDLM_02552 6.7e-107 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
OKBOLDLM_02553 2.4e-71 zur P Belongs to the Fur family
OKBOLDLM_02554 1.1e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
OKBOLDLM_02555 9.3e-37 yqfT S Protein of unknown function (DUF2624)
OKBOLDLM_02556 2.9e-162 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
OKBOLDLM_02557 5.7e-239 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
OKBOLDLM_02558 1.6e-25 yqfQ S YqfQ-like protein
OKBOLDLM_02559 1.9e-175 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OKBOLDLM_02560 1.8e-209 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OKBOLDLM_02561 1.6e-124 trmK 2.1.1.217 S SAM-dependent methyltransferase
OKBOLDLM_02562 1.3e-60 cccA C COG2010 Cytochrome c, mono- and diheme variants
OKBOLDLM_02563 3.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
OKBOLDLM_02564 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
OKBOLDLM_02565 8.7e-87 yaiI S Belongs to the UPF0178 family
OKBOLDLM_02566 1.4e-147 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
OKBOLDLM_02567 1.3e-111 ccpN K CBS domain
OKBOLDLM_02568 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
OKBOLDLM_02569 3.7e-173 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
OKBOLDLM_02570 6.1e-140 recO L Involved in DNA repair and RecF pathway recombination
OKBOLDLM_02571 1.8e-16 S YqzL-like protein
OKBOLDLM_02572 5.2e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OKBOLDLM_02573 2.7e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
OKBOLDLM_02574 8.6e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
OKBOLDLM_02575 9.7e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OKBOLDLM_02576 0.0 yqfF S membrane-associated HD superfamily hydrolase
OKBOLDLM_02577 2.1e-174 phoH T Phosphate starvation-inducible protein PhoH
OKBOLDLM_02578 1.1e-207 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
OKBOLDLM_02579 9.3e-46 yqfC S sporulation protein YqfC
OKBOLDLM_02580 4.5e-23 yqfB
OKBOLDLM_02581 5.3e-120 yqfA S UPF0365 protein
OKBOLDLM_02582 1.8e-224 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
OKBOLDLM_02583 1.2e-68 yqeY S Yqey-like protein
OKBOLDLM_02584 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
OKBOLDLM_02585 1.7e-152 yqeW P COG1283 Na phosphate symporter
OKBOLDLM_02586 1.5e-258 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
OKBOLDLM_02587 2.8e-137 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
OKBOLDLM_02588 6.6e-173 prmA J Methylates ribosomal protein L11
OKBOLDLM_02589 2.7e-197 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
OKBOLDLM_02590 0.0 dnaK O Heat shock 70 kDa protein
OKBOLDLM_02591 8.9e-72 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OKBOLDLM_02592 5.2e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
OKBOLDLM_02593 2.6e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
OKBOLDLM_02594 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
OKBOLDLM_02595 3.8e-54 yqxA S Protein of unknown function (DUF3679)
OKBOLDLM_02596 2.4e-220 spoIIP M stage II sporulation protein P
OKBOLDLM_02597 2.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
OKBOLDLM_02598 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
OKBOLDLM_02599 2.7e-180 holA 2.7.7.7 L DNA polymerase III delta subunit
OKBOLDLM_02600 0.0 comEC S Competence protein ComEC
OKBOLDLM_02601 8e-105 comEB 3.5.4.12 F ComE operon protein 2
OKBOLDLM_02602 7.3e-104 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
OKBOLDLM_02603 4.2e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OKBOLDLM_02604 3.2e-138 yqeM Q Methyltransferase
OKBOLDLM_02605 7.6e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
OKBOLDLM_02606 1.8e-101 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
OKBOLDLM_02607 9.5e-106 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OKBOLDLM_02608 2.4e-44 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
OKBOLDLM_02609 1.3e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OKBOLDLM_02610 3.8e-212 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
OKBOLDLM_02611 2e-94 yqeG S hydrolase of the HAD superfamily
OKBOLDLM_02613 4.1e-138 yqeF E GDSL-like Lipase/Acylhydrolase
OKBOLDLM_02614 8.4e-139 3.5.1.104 G Polysaccharide deacetylase
OKBOLDLM_02615 3.6e-106 yqeD S SNARE associated Golgi protein
OKBOLDLM_02616 3.2e-10 2.3.1.57 K Acetyltransferase (GNAT) domain
OKBOLDLM_02618 1.4e-215 EGP Major facilitator Superfamily
OKBOLDLM_02619 7.4e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OKBOLDLM_02620 3.9e-276 cisA2 L Recombinase
OKBOLDLM_02621 2.9e-07 yrkD S protein conserved in bacteria
OKBOLDLM_02622 1.8e-104 yrkC G Cupin domain
OKBOLDLM_02624 1.9e-20 S response regulator aspartate phosphatase
OKBOLDLM_02625 2.6e-64 S Tetratricopeptide repeat
OKBOLDLM_02626 2.3e-29
OKBOLDLM_02627 5.4e-229 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
OKBOLDLM_02628 5e-27 yokK S SMI1 / KNR4 family
OKBOLDLM_02630 3.2e-59
OKBOLDLM_02632 7.9e-138 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
OKBOLDLM_02633 1.3e-67 S Bacteriophage holin family
OKBOLDLM_02634 2.2e-157 xepA
OKBOLDLM_02635 7.9e-21
OKBOLDLM_02636 1e-51 xkdW S XkdW protein
OKBOLDLM_02637 1.6e-218
OKBOLDLM_02638 1.8e-38
OKBOLDLM_02639 1.1e-96 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
OKBOLDLM_02640 1.8e-187 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
OKBOLDLM_02641 6.9e-69 xkdS S Protein of unknown function (DUF2634)
OKBOLDLM_02642 7.2e-32 xkdR S Protein of unknown function (DUF2577)
OKBOLDLM_02643 7.9e-177 yqbQ 3.2.1.96 G NLP P60 protein
OKBOLDLM_02644 2.9e-112 xkdP S Lysin motif
OKBOLDLM_02645 0.0 xkdO L Transglycosylase SLT domain
OKBOLDLM_02646 2.3e-67 S Phage XkdN-like tail assembly chaperone protein, TAC
OKBOLDLM_02647 3.2e-202 2.7.7.49 L PFAM Reverse transcriptase (RNA-dependent DNA polymerase)
OKBOLDLM_02648 1.4e-75 xkdM S Phage tail tube protein
OKBOLDLM_02649 6.3e-252 xkdK S Phage tail sheath C-terminal domain
OKBOLDLM_02650 1.3e-24
OKBOLDLM_02651 1.9e-74
OKBOLDLM_02652 1.2e-86 S Bacteriophage HK97-gp10, putative tail-component
OKBOLDLM_02653 3.1e-62 yqbH S Domain of unknown function (DUF3599)
OKBOLDLM_02654 2.7e-67 S Protein of unknown function (DUF3199)
OKBOLDLM_02655 1.3e-45 S YqbF, hypothetical protein domain
OKBOLDLM_02656 3.2e-167 xkdG S Phage capsid family
OKBOLDLM_02657 3.1e-117 yqbD 2.1.1.72 L Putative phage serine protease XkdF
OKBOLDLM_02659 1.5e-148 S Phage Mu protein F like protein
OKBOLDLM_02660 1.4e-289 yqbA S portal protein
OKBOLDLM_02661 4.2e-250 S phage terminase, large subunit
OKBOLDLM_02662 6.4e-76 yqaS L DNA packaging
OKBOLDLM_02663 4.5e-59
OKBOLDLM_02664 2e-07
OKBOLDLM_02667 2.1e-76 L Transposase
OKBOLDLM_02668 2.6e-75 S Beta protein
OKBOLDLM_02669 2.4e-54 S Psort location Cytoplasmic, score
OKBOLDLM_02670 1.1e-30 yqaO S Phage-like element PBSX protein XtrA
OKBOLDLM_02671 4.4e-71 rusA L Endodeoxyribonuclease RusA
OKBOLDLM_02673 2.6e-163 xkdC L IstB-like ATP binding protein
OKBOLDLM_02674 2.4e-114 3.1.3.16 L DnaD domain protein
OKBOLDLM_02675 1.9e-150 recT L RecT family
OKBOLDLM_02676 3.4e-164 yqaJ L YqaJ-like viral recombinase domain
OKBOLDLM_02680 4.4e-103
OKBOLDLM_02682 1.6e-35 K Helix-turn-helix XRE-family like proteins
OKBOLDLM_02683 1.1e-56 K sequence-specific DNA binding
OKBOLDLM_02684 1.1e-11 S Protein of unknown function (DUF4064)
OKBOLDLM_02686 3.1e-95 yqaB E IrrE N-terminal-like domain
OKBOLDLM_02687 1.4e-61 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OKBOLDLM_02688 1.6e-14 cisA2 L Recombinase
OKBOLDLM_02689 8.1e-151 smc L AAA ATPase domain
OKBOLDLM_02690 1e-40 IQ Enoyl-(Acyl carrier protein) reductase
OKBOLDLM_02691 3.3e-13 Q Non-ribosomal peptide synthetase modules and related proteins
OKBOLDLM_02692 2.9e-159 efpA EGP Major facilitator superfamily
OKBOLDLM_02693 4.3e-77 pabA 2.6.1.85, 4.1.3.27 EH TIGRFAM glutamine amidotransferase of anthranilate synthase
OKBOLDLM_02694 4.4e-181 trpE 4.1.3.27 EH Anthranilate synthase component I domain protein
OKBOLDLM_02695 1.2e-175 6.2.1.30 H phenylacetate-CoA ligase activity
OKBOLDLM_02696 0.0 Q AMP-binding enzyme C-terminal domain
OKBOLDLM_02697 1.7e-306 Q AMP-binding enzyme C-terminal domain
OKBOLDLM_02698 7.2e-124 S Winged helix DNA-binding domain
OKBOLDLM_02699 6.1e-204 glyA_1 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OKBOLDLM_02700 3.3e-114 mchB Q Thioesterase involved in non-ribosomal peptide biosynthesis
OKBOLDLM_02702 4.1e-162 yobV9 K HTH domain
OKBOLDLM_02703 3.1e-105 yoaZ S DJ-1/PfpI family
OKBOLDLM_02704 6.4e-19
OKBOLDLM_02708 1.7e-20 S SMI1-KNR4 cell-wall
OKBOLDLM_02710 1e-13 xkdS S Protein of unknown function (DUF2634)
OKBOLDLM_02711 2.9e-109 5.1.1.13 M Belongs to the aspartate glutamate racemases family
OKBOLDLM_02712 6.6e-25 xkdR S Protein of unknown function (DUF2577)
OKBOLDLM_02713 1.1e-137 yvgN 1.1.1.346 S Reductase
OKBOLDLM_02714 3.2e-69 K MerR family transcriptional regulator
OKBOLDLM_02715 5.7e-16 xkdG S Phage capsid family
OKBOLDLM_02716 5.4e-158 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
OKBOLDLM_02717 2.3e-60 K Transcriptional regulator PadR-like family
OKBOLDLM_02718 1e-36 ydeE K AraC family transcriptional regulator
OKBOLDLM_02720 4.4e-97 adk 2.7.4.3 F adenylate kinase activity
OKBOLDLM_02721 2.8e-220 tetL EGP Major facilitator Superfamily
OKBOLDLM_02722 3.3e-81 yyaR K Acetyltransferase (GNAT) domain
OKBOLDLM_02723 4.4e-91 yrdA S DinB family
OKBOLDLM_02725 8.5e-145 S hydrolase
OKBOLDLM_02726 1.7e-72 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
OKBOLDLM_02727 1.2e-51 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
OKBOLDLM_02728 7.8e-129 glvR K Helix-turn-helix domain, rpiR family
OKBOLDLM_02729 5.8e-185 manA 5.3.1.8 G mannose-6-phosphate isomerase
OKBOLDLM_02730 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
OKBOLDLM_02731 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
OKBOLDLM_02732 1.3e-179 romA S Beta-lactamase superfamily domain
OKBOLDLM_02733 8.9e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OKBOLDLM_02734 4.1e-164 yybE K Transcriptional regulator
OKBOLDLM_02735 3.8e-213 ynfM EGP Major facilitator Superfamily
OKBOLDLM_02736 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
OKBOLDLM_02737 1.2e-100 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
OKBOLDLM_02738 1.5e-92 yrhH Q methyltransferase
OKBOLDLM_02740 8.8e-142 focA P Formate nitrite
OKBOLDLM_02741 1.9e-59 yrhF S Uncharacterized conserved protein (DUF2294)
OKBOLDLM_02742 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
OKBOLDLM_02743 7e-81 yrhD S Protein of unknown function (DUF1641)
OKBOLDLM_02744 1.3e-34 yrhC S YrhC-like protein
OKBOLDLM_02745 1.4e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
OKBOLDLM_02746 8e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
OKBOLDLM_02747 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OKBOLDLM_02748 7.1e-118 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
OKBOLDLM_02749 4.1e-27 yrzA S Protein of unknown function (DUF2536)
OKBOLDLM_02750 2.6e-68 yrrS S Protein of unknown function (DUF1510)
OKBOLDLM_02751 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
OKBOLDLM_02752 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
OKBOLDLM_02753 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
OKBOLDLM_02754 1.6e-246 yegQ O COG0826 Collagenase and related proteases
OKBOLDLM_02755 2.9e-173 yegQ O Peptidase U32
OKBOLDLM_02756 4e-116 yrrM 2.1.1.104 S O-methyltransferase
OKBOLDLM_02757 2.6e-189 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OKBOLDLM_02758 7.1e-46 yrzB S Belongs to the UPF0473 family
OKBOLDLM_02759 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OKBOLDLM_02760 1.7e-41 yrzL S Belongs to the UPF0297 family
OKBOLDLM_02761 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OKBOLDLM_02762 2.1e-159 yrrI S AI-2E family transporter
OKBOLDLM_02763 2.5e-127 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OKBOLDLM_02764 4.4e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
OKBOLDLM_02765 8e-109 gluC P ABC transporter
OKBOLDLM_02766 6e-104 glnP P ABC transporter
OKBOLDLM_02767 2.1e-08 S Protein of unknown function (DUF3918)
OKBOLDLM_02768 2.9e-30 yrzR
OKBOLDLM_02769 2.3e-78 yrrD S protein conserved in bacteria
OKBOLDLM_02770 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
OKBOLDLM_02771 1.7e-18 S COG0457 FOG TPR repeat
OKBOLDLM_02772 5e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
OKBOLDLM_02773 7e-209 iscS 2.8.1.7 E Cysteine desulfurase
OKBOLDLM_02774 2.9e-63 cymR K Transcriptional regulator
OKBOLDLM_02775 7e-234 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
OKBOLDLM_02776 3.3e-138 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
OKBOLDLM_02777 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OKBOLDLM_02778 4.5e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
OKBOLDLM_02781 1e-266 lytH 3.5.1.28 M COG3103 SH3 domain protein
OKBOLDLM_02782 2e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
OKBOLDLM_02783 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OKBOLDLM_02784 8.6e-90 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OKBOLDLM_02785 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
OKBOLDLM_02786 2.7e-44 yrvD S Lipopolysaccharide assembly protein A domain
OKBOLDLM_02787 4.6e-80 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
OKBOLDLM_02788 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OKBOLDLM_02789 8e-48 yrzD S Post-transcriptional regulator
OKBOLDLM_02790 9.1e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OKBOLDLM_02791 5.1e-103 yrbG S membrane
OKBOLDLM_02792 5.3e-60 yrzE S Protein of unknown function (DUF3792)
OKBOLDLM_02793 2.5e-37 yajC U Preprotein translocase subunit YajC
OKBOLDLM_02794 7.5e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
OKBOLDLM_02795 2.7e-191 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OKBOLDLM_02796 2.8e-20 yrzS S Protein of unknown function (DUF2905)
OKBOLDLM_02797 2.9e-182 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
OKBOLDLM_02798 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
OKBOLDLM_02799 5.9e-91 bofC S BofC C-terminal domain
OKBOLDLM_02801 6.1e-47 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OKBOLDLM_02802 2.1e-112 safA M spore coat assembly protein SafA
OKBOLDLM_02803 3.5e-205 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OKBOLDLM_02804 1e-140 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
OKBOLDLM_02805 1.3e-277 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
OKBOLDLM_02806 3.4e-211 nifS 2.8.1.7 E Cysteine desulfurase
OKBOLDLM_02807 2.9e-88 niaR S small molecule binding protein (contains 3H domain)
OKBOLDLM_02808 6.1e-157 pheA 4.2.1.51 E Prephenate dehydratase
OKBOLDLM_02809 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
OKBOLDLM_02810 6.4e-235 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OKBOLDLM_02811 4.8e-105 spo0B T Sporulation initiation phospho-transferase B, C-terminal
OKBOLDLM_02812 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
OKBOLDLM_02813 7e-56 ysxB J ribosomal protein
OKBOLDLM_02814 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
OKBOLDLM_02815 2.3e-156 spoIVFB S Stage IV sporulation protein
OKBOLDLM_02816 3.8e-137 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
OKBOLDLM_02817 2.3e-142 minD D Belongs to the ParA family
OKBOLDLM_02818 2.2e-101 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
OKBOLDLM_02819 1.1e-81 mreD M shape-determining protein
OKBOLDLM_02820 6.8e-156 mreC M Involved in formation and maintenance of cell shape
OKBOLDLM_02821 1.3e-182 mreB D Rod shape-determining protein MreB
OKBOLDLM_02822 4.5e-126 radC E Belongs to the UPF0758 family
OKBOLDLM_02823 3.8e-99 maf D septum formation protein Maf
OKBOLDLM_02824 2.1e-124 spoIIB S Sporulation related domain
OKBOLDLM_02825 4.6e-124 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
OKBOLDLM_02826 1.2e-228 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
OKBOLDLM_02827 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
OKBOLDLM_02828 3.1e-24
OKBOLDLM_02829 4.9e-185 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OKBOLDLM_02830 5.7e-150 spoVID M stage VI sporulation protein D
OKBOLDLM_02831 7.1e-242 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
OKBOLDLM_02832 2.1e-182 hemB 4.2.1.24 H Belongs to the ALAD family
OKBOLDLM_02833 1.1e-136 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
OKBOLDLM_02834 1.8e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
OKBOLDLM_02835 3.6e-146 hemX O cytochrome C
OKBOLDLM_02836 2.1e-244 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OKBOLDLM_02837 5.1e-84 ysxD
OKBOLDLM_02838 1.5e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
OKBOLDLM_02839 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OKBOLDLM_02840 1e-309 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
OKBOLDLM_02841 1.9e-228 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OKBOLDLM_02842 7.5e-212 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
OKBOLDLM_02843 1e-187 ysoA H Tetratricopeptide repeat
OKBOLDLM_02844 1.3e-113 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OKBOLDLM_02845 2.5e-272 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OKBOLDLM_02846 6.5e-196 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
OKBOLDLM_02847 9e-284 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OKBOLDLM_02848 2.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OKBOLDLM_02849 3.5e-83 ilvN 2.2.1.6 E Acetolactate synthase
OKBOLDLM_02850 0.0 ilvB 2.2.1.6 E Acetolactate synthase
OKBOLDLM_02855 6.1e-88 ysnB S Phosphoesterase
OKBOLDLM_02856 8e-100 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OKBOLDLM_02857 5.8e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OKBOLDLM_02858 3.4e-197 gerM S COG5401 Spore germination protein
OKBOLDLM_02859 6.2e-151 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
OKBOLDLM_02860 4.1e-72 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
OKBOLDLM_02861 2e-30 gerE K Transcriptional regulator
OKBOLDLM_02862 2.1e-73 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
OKBOLDLM_02863 3.9e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
OKBOLDLM_02864 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
OKBOLDLM_02865 4.8e-108 sdhC C succinate dehydrogenase
OKBOLDLM_02866 3.5e-79 yslB S Protein of unknown function (DUF2507)
OKBOLDLM_02867 1.2e-211 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
OKBOLDLM_02868 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
OKBOLDLM_02869 2.5e-52 trxA O Belongs to the thioredoxin family
OKBOLDLM_02870 8.9e-297 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
OKBOLDLM_02871 3e-176 etfA C Electron transfer flavoprotein
OKBOLDLM_02872 2.2e-137 etfB C Electron transfer flavoprotein
OKBOLDLM_02873 3.6e-132 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
OKBOLDLM_02874 2.7e-103 fadR K Transcriptional regulator
OKBOLDLM_02875 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OKBOLDLM_02876 2e-115 ywbB S Protein of unknown function (DUF2711)
OKBOLDLM_02877 4.7e-67 yshE S membrane
OKBOLDLM_02878 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
OKBOLDLM_02879 0.0 polX L COG1796 DNA polymerase IV (family X)
OKBOLDLM_02880 2.3e-82 cvpA S membrane protein, required for colicin V production
OKBOLDLM_02881 2e-39 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
OKBOLDLM_02882 1.5e-164 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OKBOLDLM_02883 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
OKBOLDLM_02884 3.4e-194 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OKBOLDLM_02885 1.4e-128 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OKBOLDLM_02886 7.6e-32 sspI S Belongs to the SspI family
OKBOLDLM_02887 4.8e-191 ysfB KT regulator
OKBOLDLM_02888 3.4e-253 glcD 1.1.3.15 C FAD binding domain
OKBOLDLM_02889 1.4e-245 glcF C Glycolate oxidase
OKBOLDLM_02890 0.0 cstA T Carbon starvation protein
OKBOLDLM_02891 7e-187 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
OKBOLDLM_02893 1.5e-109 istB2 L IstB-like ATP binding protein
OKBOLDLM_02894 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
OKBOLDLM_02895 3e-238 3.2.1.11 GH66 G Glycosyl hydrolase family 66
OKBOLDLM_02896 4.1e-70 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
OKBOLDLM_02898 1.5e-26 U TraM recognition site of TraD and TraG
OKBOLDLM_02901 1.5e-134 L Integrase core domain
OKBOLDLM_02902 6e-44 tnpIS3 L Transposase
OKBOLDLM_02903 8.6e-230 M domain protein
OKBOLDLM_02908 9.5e-09 ddpX 3.4.13.22 F protein conserved in bacteria
OKBOLDLM_02910 5.2e-07 K transcriptional
OKBOLDLM_02912 5.5e-57 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
OKBOLDLM_02913 1.4e-55 araQ G transport system permease
OKBOLDLM_02914 2.8e-163 araP P PFAM binding-protein-dependent transport systems inner membrane component
OKBOLDLM_02915 4.3e-247 araN G carbohydrate transport
OKBOLDLM_02916 8.4e-185 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
OKBOLDLM_02918 2e-136 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
OKBOLDLM_02919 7.1e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
OKBOLDLM_02920 2.2e-307 araB 2.7.1.16 C Belongs to the ribulokinase family
OKBOLDLM_02921 3.3e-291 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
OKBOLDLM_02922 1.3e-184 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
OKBOLDLM_02923 4e-206 ysdC G COG1363 Cellulase M and related proteins
OKBOLDLM_02924 2.6e-62 ysdB S Sigma-w pathway protein YsdB
OKBOLDLM_02925 1.8e-38 ysdA S Membrane
OKBOLDLM_02926 2.7e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OKBOLDLM_02927 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
OKBOLDLM_02928 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OKBOLDLM_02929 2.7e-107 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
OKBOLDLM_02930 5.5e-37 lrgA S effector of murein hydrolase LrgA
OKBOLDLM_02931 1e-128 lytT T COG3279 Response regulator of the LytR AlgR family
OKBOLDLM_02932 0.0 lytS 2.7.13.3 T Histidine kinase
OKBOLDLM_02933 4.1e-147 ysaA S HAD-hyrolase-like
OKBOLDLM_02934 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OKBOLDLM_02935 1.6e-149 ytxC S YtxC-like family
OKBOLDLM_02936 1.8e-105 ytxB S SNARE associated Golgi protein
OKBOLDLM_02937 2.9e-168 dnaI L Primosomal protein DnaI
OKBOLDLM_02938 7.7e-250 dnaB L Membrane attachment protein
OKBOLDLM_02939 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OKBOLDLM_02940 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
OKBOLDLM_02941 1.3e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
OKBOLDLM_02942 1.6e-64 ytcD K Transcriptional regulator
OKBOLDLM_02943 5.8e-198 ytbD EGP Major facilitator Superfamily
OKBOLDLM_02944 6.8e-153 ytbE S reductase
OKBOLDLM_02945 3.9e-94 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OKBOLDLM_02946 2.6e-104 ytaF P Probably functions as a manganese efflux pump
OKBOLDLM_02947 2.7e-154 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
OKBOLDLM_02948 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OKBOLDLM_02949 2.6e-308 phoR 2.7.13.3 T Signal transduction histidine kinase
OKBOLDLM_02950 5e-128 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OKBOLDLM_02951 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
OKBOLDLM_02952 2e-241 icd 1.1.1.42 C isocitrate
OKBOLDLM_02953 8.1e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
OKBOLDLM_02954 1.5e-72 yeaL S membrane
OKBOLDLM_02955 1.8e-193 ytvI S sporulation integral membrane protein YtvI
OKBOLDLM_02956 1.1e-62 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
OKBOLDLM_02957 1.2e-292 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
OKBOLDLM_02958 9.8e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
OKBOLDLM_02959 2.4e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
OKBOLDLM_02960 6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OKBOLDLM_02961 5.9e-222 ytsJ 1.1.1.38 C Malate dehydrogenase
OKBOLDLM_02962 0.0 dnaE 2.7.7.7 L DNA polymerase
OKBOLDLM_02963 3.9e-54 ytrH S Sporulation protein YtrH
OKBOLDLM_02964 5.6e-86 ytrI
OKBOLDLM_02965 6.4e-22
OKBOLDLM_02966 2.9e-176 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
OKBOLDLM_02967 3.8e-45 ytpI S YtpI-like protein
OKBOLDLM_02968 6.8e-238 ytoI K transcriptional regulator containing CBS domains
OKBOLDLM_02969 1.1e-127 ytkL S Belongs to the UPF0173 family
OKBOLDLM_02970 3.6e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OKBOLDLM_02972 6.1e-260 argH 4.3.2.1 E argininosuccinate lyase
OKBOLDLM_02973 4.3e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
OKBOLDLM_02974 8e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
OKBOLDLM_02975 4.5e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OKBOLDLM_02976 9.7e-175 ytxK 2.1.1.72 L DNA methylase
OKBOLDLM_02977 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
OKBOLDLM_02978 1.5e-63 ytfJ S Sporulation protein YtfJ
OKBOLDLM_02979 4.1e-111 ytfI S Protein of unknown function (DUF2953)
OKBOLDLM_02980 4.5e-80 yteJ S RDD family
OKBOLDLM_02981 1.4e-176 sppA OU signal peptide peptidase SppA
OKBOLDLM_02982 5.9e-149 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OKBOLDLM_02983 8.3e-301 ytcJ S amidohydrolase
OKBOLDLM_02984 9.1e-300 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
OKBOLDLM_02985 6.6e-31 sspB S spore protein
OKBOLDLM_02986 1.4e-220 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OKBOLDLM_02987 3.4e-203 iscS2 2.8.1.7 E Cysteine desulfurase
OKBOLDLM_02988 6.4e-238 braB E Component of the transport system for branched-chain amino acids
OKBOLDLM_02989 4e-261 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
OKBOLDLM_02990 7.3e-144 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
OKBOLDLM_02991 7.9e-106 yttP K Transcriptional regulator
OKBOLDLM_02992 8.6e-84 ytsP 1.8.4.14 T GAF domain-containing protein
OKBOLDLM_02993 4.6e-268 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
OKBOLDLM_02994 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OKBOLDLM_02995 5.8e-214 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OKBOLDLM_02997 1.3e-08 yhbO 1.11.1.6, 3.5.1.124 S protease
OKBOLDLM_02999 2.9e-126 E GDSL-like Lipase/Acylhydrolase family
OKBOLDLM_03000 5.8e-147 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OKBOLDLM_03001 5.4e-147 K Transcriptional regulator
OKBOLDLM_03002 1.9e-119 azlC E AzlC protein
OKBOLDLM_03003 7.4e-47 azlD S Branched-chain amino acid transport protein (AzlD)
OKBOLDLM_03004 4.7e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OKBOLDLM_03005 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
OKBOLDLM_03006 1.7e-119 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
OKBOLDLM_03007 2e-107 acuB S Domain in cystathionine beta-synthase and other proteins.
OKBOLDLM_03008 7.9e-224 acuC BQ histone deacetylase
OKBOLDLM_03009 2.7e-98 motS N Flagellar motor protein
OKBOLDLM_03010 4.8e-143 motA N flagellar motor
OKBOLDLM_03011 3.9e-179 ccpA K catabolite control protein A
OKBOLDLM_03012 1.6e-194 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
OKBOLDLM_03013 2.2e-43 ytxJ O Protein of unknown function (DUF2847)
OKBOLDLM_03014 1.7e-16 ytxH S COG4980 Gas vesicle protein
OKBOLDLM_03015 1.1e-13 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
OKBOLDLM_03016 7.1e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
OKBOLDLM_03017 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
OKBOLDLM_03018 5.9e-106 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
OKBOLDLM_03019 3e-145 ytpQ S Belongs to the UPF0354 family
OKBOLDLM_03020 3.5e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
OKBOLDLM_03021 1.8e-75 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
OKBOLDLM_03022 4.1e-203 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
OKBOLDLM_03023 1.7e-51 ytzB S small secreted protein
OKBOLDLM_03024 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
OKBOLDLM_03025 3.4e-160 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
OKBOLDLM_03026 1.5e-123 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
OKBOLDLM_03027 1.3e-44 ytzH S YtzH-like protein
OKBOLDLM_03028 4.1e-155 ytmP 2.7.1.89 M Phosphotransferase
OKBOLDLM_03029 2.6e-169 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
OKBOLDLM_03030 5.1e-141 ytlQ
OKBOLDLM_03031 2.4e-98 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
OKBOLDLM_03032 1.6e-166 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
OKBOLDLM_03033 6.2e-260 pepV 3.5.1.18 E Dipeptidase
OKBOLDLM_03034 5.5e-226 pbuO S permease
OKBOLDLM_03035 1.5e-198 ythQ U Bacterial ABC transporter protein EcsB
OKBOLDLM_03036 1.9e-116 ythP V ABC transporter
OKBOLDLM_03037 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
OKBOLDLM_03038 2e-124 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
OKBOLDLM_03039 1.5e-292 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OKBOLDLM_03040 5.5e-231 ytfP S HI0933-like protein
OKBOLDLM_03041 1.4e-276 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
OKBOLDLM_03042 2.6e-25 yteV S Sporulation protein Cse60
OKBOLDLM_03043 7.2e-181 msmR K Transcriptional regulator
OKBOLDLM_03044 4.1e-234 msmE G Bacterial extracellular solute-binding protein
OKBOLDLM_03045 3.9e-60 amyD G Binding-protein-dependent transport system inner membrane component
OKBOLDLM_03046 1.3e-245 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
OKBOLDLM_03047 1.1e-73 M Acetyltransferase (GNAT) domain
OKBOLDLM_03048 1.3e-51 ytwF P Sulfurtransferase
OKBOLDLM_03049 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
OKBOLDLM_03050 1.2e-52 ytvB S Protein of unknown function (DUF4257)
OKBOLDLM_03051 3e-134 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
OKBOLDLM_03052 4.9e-205 yttB EGP Major facilitator Superfamily
OKBOLDLM_03053 4e-102 ywaF S Integral membrane protein
OKBOLDLM_03054 0.0 bceB V ABC transporter (permease)
OKBOLDLM_03055 2.7e-132 bceA V ABC transporter, ATP-binding protein
OKBOLDLM_03056 7.4e-162 T PhoQ Sensor
OKBOLDLM_03057 1.1e-121 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OKBOLDLM_03058 5.8e-199 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
OKBOLDLM_03059 1.1e-124 ytrE V ABC transporter, ATP-binding protein
OKBOLDLM_03060 1.1e-144
OKBOLDLM_03061 7.8e-148 P ABC-2 family transporter protein
OKBOLDLM_03062 1.9e-162 S ABC-2 family transporter protein
OKBOLDLM_03063 1.4e-156 ytrB P abc transporter atp-binding protein
OKBOLDLM_03064 4.3e-65 ytrA K GntR family transcriptional regulator
OKBOLDLM_03066 8.1e-39 ytzC S Protein of unknown function (DUF2524)
OKBOLDLM_03067 1.4e-189 yhcC S Fe-S oxidoreductase
OKBOLDLM_03068 3.4e-103 ytqB J Putative rRNA methylase
OKBOLDLM_03070 7.3e-208 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
OKBOLDLM_03071 9.5e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
OKBOLDLM_03072 9e-55 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OKBOLDLM_03073 8.5e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
OKBOLDLM_03074 0.0 asnB 6.3.5.4 E Asparagine synthase
OKBOLDLM_03075 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OKBOLDLM_03076 3e-303 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
OKBOLDLM_03077 8e-38 ytmB S Protein of unknown function (DUF2584)
OKBOLDLM_03078 2.2e-145 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
OKBOLDLM_03079 1.9e-178 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
OKBOLDLM_03080 1.5e-141 ytlC P ABC transporter
OKBOLDLM_03081 3.8e-124 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
OKBOLDLM_03082 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
OKBOLDLM_03083 1.2e-59 ytkC S Bacteriophage holin family
OKBOLDLM_03084 7.8e-76 dps P Belongs to the Dps family
OKBOLDLM_03086 4.4e-74 ytkA S YtkA-like
OKBOLDLM_03087 2.2e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
OKBOLDLM_03088 2e-38 yidD S Could be involved in insertion of integral membrane proteins into the membrane
OKBOLDLM_03089 1.3e-102 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
OKBOLDLM_03090 7.9e-41 rpmE2 J Ribosomal protein L31
OKBOLDLM_03091 1.2e-239 cydA 1.10.3.14 C oxidase, subunit
OKBOLDLM_03092 1.2e-183 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
OKBOLDLM_03093 4e-24 S Domain of Unknown Function (DUF1540)
OKBOLDLM_03094 2e-208 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
OKBOLDLM_03095 1.7e-268 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
OKBOLDLM_03096 7.9e-154 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OKBOLDLM_03097 1.9e-147 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
OKBOLDLM_03098 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
OKBOLDLM_03099 3.7e-260 menF 5.4.4.2 HQ Isochorismate synthase
OKBOLDLM_03100 2.3e-125 dksA T COG1734 DnaK suppressor protein
OKBOLDLM_03101 4.8e-71 tspO T membrane
OKBOLDLM_03110 7.8e-08
OKBOLDLM_03111 1.3e-09
OKBOLDLM_03118 1.6e-08
OKBOLDLM_03126 2e-08
OKBOLDLM_03129 1.3e-07
OKBOLDLM_03130 2.7e-92 thiT S Thiamine transporter protein (Thia_YuaJ)
OKBOLDLM_03131 6.1e-176 yuaG 3.4.21.72 S protein conserved in bacteria
OKBOLDLM_03132 1.7e-80 yuaF OU Membrane protein implicated in regulation of membrane protease activity
OKBOLDLM_03133 2.2e-79 yuaE S DinB superfamily
OKBOLDLM_03134 1.2e-103 yuaD S MOSC domain
OKBOLDLM_03135 6.7e-226 gbsB 1.1.1.1 C alcohol dehydrogenase
OKBOLDLM_03136 2.3e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
OKBOLDLM_03137 3.4e-92 yuaC K Belongs to the GbsR family
OKBOLDLM_03138 4.3e-92 yuaB
OKBOLDLM_03139 1.7e-117 ktrA P COG0569 K transport systems, NAD-binding component
OKBOLDLM_03140 9.3e-142 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
OKBOLDLM_03141 5.2e-207 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OKBOLDLM_03142 1.7e-36 G Cupin
OKBOLDLM_03143 1.1e-42 yjcN
OKBOLDLM_03146 2.4e-132 S Aspartate phosphatase response regulator
OKBOLDLM_03147 4e-14
OKBOLDLM_03149 2.8e-143 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
OKBOLDLM_03150 5.5e-193 yubA S transporter activity
OKBOLDLM_03151 9.1e-181 ygjR S Oxidoreductase
OKBOLDLM_03152 1.5e-97 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
OKBOLDLM_03153 6.9e-228 mcpA NT chemotaxis protein
OKBOLDLM_03154 2.2e-218 mcpA NT chemotaxis protein
OKBOLDLM_03155 1.3e-213 mcpA NT chemotaxis protein
OKBOLDLM_03156 5.5e-209 mcpA NT chemotaxis protein
OKBOLDLM_03157 3.3e-135 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
OKBOLDLM_03158 5.8e-39
OKBOLDLM_03159 3.6e-186 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
OKBOLDLM_03160 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
OKBOLDLM_03161 8.1e-230 yugS S COG1253 Hemolysins and related proteins containing CBS domains
OKBOLDLM_03162 4.1e-116 yugP S Zn-dependent protease
OKBOLDLM_03163 6.5e-17
OKBOLDLM_03164 1e-27 mstX S Membrane-integrating protein Mistic
OKBOLDLM_03165 1.6e-177 yugO P COG1226 Kef-type K transport systems
OKBOLDLM_03166 5e-69 yugN S YugN-like family
OKBOLDLM_03168 1.9e-258 pgi 5.3.1.9 G Belongs to the GPI family
OKBOLDLM_03169 5.8e-227 yugK C Dehydrogenase
OKBOLDLM_03170 1e-223 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
OKBOLDLM_03171 6.8e-34 yuzA S Domain of unknown function (DUF378)
OKBOLDLM_03172 2.9e-61 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
OKBOLDLM_03173 3e-207 yugH 2.6.1.1 E Aminotransferase
OKBOLDLM_03174 5.8e-83 alaR K Transcriptional regulator
OKBOLDLM_03175 2e-149 yugF I Hydrolase
OKBOLDLM_03176 5e-38 yugE S Domain of unknown function (DUF1871)
OKBOLDLM_03177 9.9e-219 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
OKBOLDLM_03178 1.7e-138 T PhoQ Sensor
OKBOLDLM_03179 1.2e-65 T PhoQ Sensor
OKBOLDLM_03180 7.4e-62 kapB G Kinase associated protein B
OKBOLDLM_03181 4.7e-115 kapD L the KinA pathway to sporulation
OKBOLDLM_03182 1.5e-165 yuxJ EGP Major facilitator Superfamily
OKBOLDLM_03183 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
OKBOLDLM_03184 1e-69 yuxK S protein conserved in bacteria
OKBOLDLM_03185 1.1e-71 yufK S Family of unknown function (DUF5366)
OKBOLDLM_03186 4.2e-292 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
OKBOLDLM_03187 8.7e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
OKBOLDLM_03188 5.1e-193 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
OKBOLDLM_03189 1.7e-279 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
OKBOLDLM_03190 7.4e-181 yufP S Belongs to the binding-protein-dependent transport system permease family
OKBOLDLM_03191 6.6e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
OKBOLDLM_03192 9.8e-11
OKBOLDLM_03193 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
OKBOLDLM_03194 6.6e-67 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OKBOLDLM_03195 2.2e-49 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OKBOLDLM_03196 7.4e-259 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OKBOLDLM_03197 5.5e-75 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OKBOLDLM_03198 1.4e-36 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OKBOLDLM_03199 9.7e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
OKBOLDLM_03200 2.6e-59 ydiI Q protein, possibly involved in aromatic compounds catabolism
OKBOLDLM_03201 1.3e-42 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OKBOLDLM_03202 2.2e-57 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OKBOLDLM_03203 4.2e-253 comP 2.7.13.3 T Histidine kinase
OKBOLDLM_03205 2.9e-61 comQ H Belongs to the FPP GGPP synthase family
OKBOLDLM_03207 1.6e-47 yuzC
OKBOLDLM_03208 8.2e-224 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
OKBOLDLM_03209 1.7e-279 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OKBOLDLM_03210 3e-101 pncA Q COG1335 Amidases related to nicotinamidase
OKBOLDLM_03211 1.1e-65 yueI S Protein of unknown function (DUF1694)
OKBOLDLM_03212 4.8e-38 yueH S YueH-like protein
OKBOLDLM_03213 7.1e-33 yueG S Spore germination protein gerPA/gerPF
OKBOLDLM_03214 4.1e-182 yueF S transporter activity
OKBOLDLM_03215 1.6e-22 S Protein of unknown function (DUF2642)
OKBOLDLM_03216 2.4e-95 yueE S phosphohydrolase
OKBOLDLM_03217 3.4e-124 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OKBOLDLM_03218 2.7e-74 yueC S Family of unknown function (DUF5383)
OKBOLDLM_03219 0.0 esaA S type VII secretion protein EsaA
OKBOLDLM_03220 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
OKBOLDLM_03221 6.3e-198 essB S WXG100 protein secretion system (Wss), protein YukC
OKBOLDLM_03222 9.6e-39 yukD S WXG100 protein secretion system (Wss), protein YukD
OKBOLDLM_03223 1.7e-45 esxA S Belongs to the WXG100 family
OKBOLDLM_03224 6.8e-226 yukF QT Transcriptional regulator
OKBOLDLM_03225 1.3e-202 ald 1.4.1.1 E Belongs to the AlaDH PNT family
OKBOLDLM_03226 1.9e-129 yukJ S Uncharacterized conserved protein (DUF2278)
OKBOLDLM_03227 1.7e-31 mbtH S MbtH-like protein
OKBOLDLM_03228 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OKBOLDLM_03229 2.3e-162 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
OKBOLDLM_03230 3.6e-307 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
OKBOLDLM_03231 5.8e-214 entC 5.4.4.2 HQ Isochorismate synthase
OKBOLDLM_03232 2.2e-129 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OKBOLDLM_03233 8.9e-156 besA S Putative esterase
OKBOLDLM_03234 3e-118 yuiH S Oxidoreductase molybdopterin binding domain
OKBOLDLM_03235 1.2e-100 bioY S Biotin biosynthesis protein
OKBOLDLM_03236 1.5e-207 yuiF S antiporter
OKBOLDLM_03237 1.2e-277 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OKBOLDLM_03238 6.5e-76 yuiD S protein conserved in bacteria
OKBOLDLM_03239 1.3e-114 yuiC S protein conserved in bacteria
OKBOLDLM_03240 4.9e-27 yuiB S Putative membrane protein
OKBOLDLM_03241 1.1e-233 yumB 1.6.99.3 C NADH dehydrogenase
OKBOLDLM_03242 1.8e-184 yumC 1.18.1.2, 1.19.1.1 C reductase
OKBOLDLM_03244 3e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
OKBOLDLM_03245 2e-27
OKBOLDLM_03246 1.4e-66 CP Membrane
OKBOLDLM_03247 3.5e-118 V ABC transporter
OKBOLDLM_03249 5.4e-32 S Bacteriocin class IId cyclical uberolysin-like
OKBOLDLM_03251 6.6e-42 rimJ 2.3.1.128 J Alanine acetyltransferase
OKBOLDLM_03252 1.3e-129 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
OKBOLDLM_03253 2.6e-61 erpA S Belongs to the HesB IscA family
OKBOLDLM_03254 3.8e-159 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OKBOLDLM_03255 3.6e-203 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OKBOLDLM_03256 1.7e-37 yuzB S Belongs to the UPF0349 family
OKBOLDLM_03257 5.7e-205 yutJ 1.6.99.3 C NADH dehydrogenase
OKBOLDLM_03258 4.1e-53 yuzD S protein conserved in bacteria
OKBOLDLM_03259 1.6e-35 yutI O COG0694 Thioredoxin-like proteins and domains
OKBOLDLM_03260 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
OKBOLDLM_03261 3.1e-162 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
OKBOLDLM_03262 4.5e-194 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OKBOLDLM_03263 5.1e-240 hom 1.1.1.3 E homoserine dehydrogenase
OKBOLDLM_03264 6.3e-193 yutH S Spore coat protein
OKBOLDLM_03265 5.2e-84 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
OKBOLDLM_03266 7.9e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
OKBOLDLM_03267 8.9e-72 yutE S Protein of unknown function DUF86
OKBOLDLM_03268 1.7e-47 yutD S protein conserved in bacteria
OKBOLDLM_03269 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OKBOLDLM_03270 2.5e-191 lytH M Peptidase, M23
OKBOLDLM_03271 1.1e-128 yunB S Sporulation protein YunB (Spo_YunB)
OKBOLDLM_03272 1.2e-255 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
OKBOLDLM_03273 4.8e-143 yunE S membrane transporter protein
OKBOLDLM_03274 9.9e-168 yunF S Protein of unknown function DUF72
OKBOLDLM_03275 2.1e-55 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
OKBOLDLM_03276 2.7e-252 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
OKBOLDLM_03277 1.7e-293 pucR QT COG2508 Regulator of polyketide synthase expression
OKBOLDLM_03278 2.8e-65
OKBOLDLM_03279 1.4e-207 blt EGP Major facilitator Superfamily
OKBOLDLM_03280 1.2e-225 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
OKBOLDLM_03281 6.4e-224 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
OKBOLDLM_03282 3.7e-162 bsn L Ribonuclease
OKBOLDLM_03283 7e-198 msmX P Belongs to the ABC transporter superfamily
OKBOLDLM_03284 1.5e-132 yurK K UTRA
OKBOLDLM_03285 2.5e-158 yurL 2.7.1.218 G pfkB family carbohydrate kinase
OKBOLDLM_03286 2e-155 yurM P COG0395 ABC-type sugar transport system, permease component
OKBOLDLM_03287 2.2e-157 yurN G Binding-protein-dependent transport system inner membrane component
OKBOLDLM_03288 2.1e-238 yurO G COG1653 ABC-type sugar transport system, periplasmic component
OKBOLDLM_03289 5.3e-181 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
OKBOLDLM_03290 8.3e-160 K helix_turn_helix, mercury resistance
OKBOLDLM_03291 1e-14
OKBOLDLM_03292 5.3e-77
OKBOLDLM_03294 3.8e-10 S Sporulation delaying protein SdpA
OKBOLDLM_03296 2.6e-64 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
OKBOLDLM_03297 3.5e-197 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
OKBOLDLM_03298 3.4e-101 Q ubiE/COQ5 methyltransferase family
OKBOLDLM_03299 1.1e-72 yncE S Protein of unknown function (DUF2691)
OKBOLDLM_03300 1.9e-150 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
OKBOLDLM_03301 8.7e-270 sufB O FeS cluster assembly
OKBOLDLM_03302 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
OKBOLDLM_03303 2.8e-232 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OKBOLDLM_03304 7e-245 sufD O assembly protein SufD
OKBOLDLM_03305 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
OKBOLDLM_03306 6.7e-09
OKBOLDLM_03307 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OKBOLDLM_03308 4e-142 metQ P Belongs to the NlpA lipoprotein family
OKBOLDLM_03309 8.3e-93 metI P COG2011 ABC-type metal ion transport system, permease component
OKBOLDLM_03310 5.4e-184 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OKBOLDLM_03311 2.1e-55 yusD S SCP-2 sterol transfer family
OKBOLDLM_03312 5.2e-53 yusE CO Thioredoxin
OKBOLDLM_03313 9.7e-22 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
OKBOLDLM_03314 2.1e-38 yusG S Protein of unknown function (DUF2553)
OKBOLDLM_03315 5.5e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
OKBOLDLM_03316 1.8e-62 arsC 1.20.4.1 P Belongs to the ArsC family
OKBOLDLM_03317 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
OKBOLDLM_03318 1e-215 fadA 2.3.1.16 I Belongs to the thiolase family
OKBOLDLM_03319 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
OKBOLDLM_03321 3.9e-162 fadM E Proline dehydrogenase
OKBOLDLM_03322 3.5e-39
OKBOLDLM_03323 1.3e-51 yusN M Coat F domain
OKBOLDLM_03324 4.5e-66 yusO K Iron dependent repressor, N-terminal DNA binding domain
OKBOLDLM_03325 5.4e-284 yusP P Major facilitator superfamily
OKBOLDLM_03326 9.8e-59 L PFAM Restriction endonuclease BamHI
OKBOLDLM_03327 1.8e-16 K Helix-turn-helix XRE-family like proteins
OKBOLDLM_03328 2.2e-126 2.1.1.72 L DNA methylase
OKBOLDLM_03329 8.1e-38 yusU S Protein of unknown function (DUF2573)
OKBOLDLM_03330 3.1e-150 yusV 3.6.3.34 HP ABC transporter
OKBOLDLM_03331 1e-46 S YusW-like protein
OKBOLDLM_03332 4.3e-228 pepF2 E COG1164 Oligoendopeptidase F
OKBOLDLM_03333 5.2e-65 pepF2 E COG1164 Oligoendopeptidase F
OKBOLDLM_03334 3.6e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OKBOLDLM_03335 1.5e-77 dps P Belongs to the Dps family
OKBOLDLM_03336 3.5e-231 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OKBOLDLM_03337 1.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OKBOLDLM_03338 6.3e-249 cssS 2.7.13.3 T PhoQ Sensor
OKBOLDLM_03339 1.3e-23
OKBOLDLM_03340 3e-154 yuxN K Transcriptional regulator
OKBOLDLM_03341 7.3e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
OKBOLDLM_03342 6.6e-24 S Protein of unknown function (DUF3970)
OKBOLDLM_03343 1.1e-254 gerAA EG Spore germination protein
OKBOLDLM_03344 4.6e-181 gerAB E Spore germination protein
OKBOLDLM_03345 7.6e-192 gerAC S Spore germination B3/ GerAC like, C-terminal
OKBOLDLM_03346 5.6e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OKBOLDLM_03347 1.1e-192 vraS 2.7.13.3 T Histidine kinase
OKBOLDLM_03348 4.4e-124 yvqF S Cell wall-active antibiotics response 4TMS YvqF
OKBOLDLM_03349 2.1e-117 liaG S Putative adhesin
OKBOLDLM_03350 8.7e-90 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
OKBOLDLM_03351 6.9e-44 liaI S membrane
OKBOLDLM_03352 1.2e-220 yvqJ EGP Major facilitator Superfamily
OKBOLDLM_03353 2.3e-96 yvqK 2.5.1.17 S Adenosyltransferase
OKBOLDLM_03354 3.1e-202 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
OKBOLDLM_03355 2.5e-176 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OKBOLDLM_03356 1.1e-164 yvrC P ABC transporter substrate-binding protein
OKBOLDLM_03357 1e-137 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OKBOLDLM_03358 4.3e-166 yvrE G SMP-30/Gluconolaconase/LRE-like region
OKBOLDLM_03359 0.0 T PhoQ Sensor
OKBOLDLM_03360 5.7e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OKBOLDLM_03361 6.2e-35
OKBOLDLM_03362 2.1e-100 yvrI K RNA polymerase
OKBOLDLM_03363 1.6e-15 S YvrJ protein family
OKBOLDLM_03364 3.3e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
OKBOLDLM_03365 9.9e-60 yvrL S Regulatory protein YrvL
OKBOLDLM_03366 4.5e-146 fhuC 3.6.3.34 HP ABC transporter
OKBOLDLM_03367 1.4e-168 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OKBOLDLM_03368 1.5e-181 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OKBOLDLM_03369 5.8e-177 fhuD P ABC transporter
OKBOLDLM_03370 4e-122 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
OKBOLDLM_03371 3e-233 yvsH E Arginine ornithine antiporter
OKBOLDLM_03372 5.2e-13 S Small spore protein J (Spore_SspJ)
OKBOLDLM_03373 3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
OKBOLDLM_03374 3e-166 ltaS 2.7.8.20 M Belongs to the LTA synthase family
OKBOLDLM_03375 3.5e-163 ltaS 2.7.8.20 M Belongs to the LTA synthase family
OKBOLDLM_03376 5.4e-159 yvgK P COG1910 Periplasmic molybdate-binding protein domain
OKBOLDLM_03377 4.2e-136 modA P COG0725 ABC-type molybdate transport system, periplasmic component
OKBOLDLM_03378 1.2e-99 modB P COG4149 ABC-type molybdate transport system, permease component
OKBOLDLM_03379 3.3e-113 yfiK K Regulator
OKBOLDLM_03380 5.6e-171 T Histidine kinase
OKBOLDLM_03381 6.8e-170 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
OKBOLDLM_03382 3e-185 yfiM V ABC-2 type transporter
OKBOLDLM_03383 7.3e-174 yfiN V COG0842 ABC-type multidrug transport system, permease component
OKBOLDLM_03384 5e-156 yvgN S reductase
OKBOLDLM_03385 2.3e-84 yvgO
OKBOLDLM_03386 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
OKBOLDLM_03387 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
OKBOLDLM_03388 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OKBOLDLM_03389 8.7e-291 helD 3.6.4.12 L DNA helicase
OKBOLDLM_03390 4.7e-81 helD 3.6.4.12 L DNA helicase
OKBOLDLM_03391 1e-97 yvgT S membrane
OKBOLDLM_03392 9.1e-139 S Metallo-peptidase family M12
OKBOLDLM_03393 8.6e-72 bdbC O Required for disulfide bond formation in some proteins
OKBOLDLM_03394 7.7e-99 bdbD O Thioredoxin
OKBOLDLM_03395 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
OKBOLDLM_03396 0.0 copA 3.6.3.54 P P-type ATPase
OKBOLDLM_03397 9.9e-29 copZ P Heavy-metal-associated domain
OKBOLDLM_03398 1.4e-47 csoR S transcriptional
OKBOLDLM_03399 8.9e-187 yvaA 1.1.1.371 S Oxidoreductase
OKBOLDLM_03400 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OKBOLDLM_03401 5.6e-250 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OKBOLDLM_03402 1e-44 ytnI O COG0695 Glutaredoxin and related proteins
OKBOLDLM_03403 9.1e-176 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OKBOLDLM_03404 1.5e-138 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OKBOLDLM_03405 5.1e-117 tcyM U Binding-protein-dependent transport system inner membrane component
OKBOLDLM_03406 2.1e-118 tcyL P Binding-protein-dependent transport system inner membrane component
OKBOLDLM_03407 2.4e-131 tcyK M Bacterial periplasmic substrate-binding proteins
OKBOLDLM_03408 1.7e-129 ytmJ ET Bacterial periplasmic substrate-binding proteins
OKBOLDLM_03409 2.5e-100 ytmI K Acetyltransferase (GNAT) domain
OKBOLDLM_03410 2.2e-157 ytlI K LysR substrate binding domain
OKBOLDLM_03411 1.5e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OKBOLDLM_03412 1.8e-42 yrdF K ribonuclease inhibitor
OKBOLDLM_03414 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OKBOLDLM_03415 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
OKBOLDLM_03416 1.6e-142 est 3.1.1.1 S Carboxylesterase
OKBOLDLM_03417 4.2e-20 secG U Preprotein translocase subunit SecG
OKBOLDLM_03418 6e-35 yvzC K Transcriptional
OKBOLDLM_03419 1.6e-67 K transcriptional
OKBOLDLM_03420 9.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
OKBOLDLM_03421 1.4e-50 yodB K transcriptional
OKBOLDLM_03422 6.5e-241 T His Kinase A (phosphoacceptor) domain
OKBOLDLM_03423 1.3e-119 K Transcriptional regulatory protein, C terminal
OKBOLDLM_03424 6.8e-131 mutG S ABC-2 family transporter protein
OKBOLDLM_03425 1e-120 spaE S ABC-2 family transporter protein
OKBOLDLM_03426 1.6e-123 mutF V ABC transporter, ATP-binding protein
OKBOLDLM_03427 4.4e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
OKBOLDLM_03428 8.2e-168 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
OKBOLDLM_03429 4.7e-109 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
OKBOLDLM_03430 2.6e-203 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
OKBOLDLM_03431 4.3e-76 yvbF K Belongs to the GbsR family
OKBOLDLM_03432 5.4e-108 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
OKBOLDLM_03433 9.7e-169 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
OKBOLDLM_03434 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
OKBOLDLM_03435 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
OKBOLDLM_03436 2.5e-95 yvbF K Belongs to the GbsR family
OKBOLDLM_03437 4.9e-103 yvbG U UPF0056 membrane protein
OKBOLDLM_03438 4.2e-108 exoY M Membrane
OKBOLDLM_03439 1.6e-288 tcaA S response to antibiotic
OKBOLDLM_03440 1.1e-18 tcaA S response to antibiotic
OKBOLDLM_03441 1.4e-78 yvbK 3.1.3.25 K acetyltransferase
OKBOLDLM_03442 7.8e-206 EGP Major facilitator Superfamily
OKBOLDLM_03443 4.2e-172
OKBOLDLM_03444 2e-123 S GlcNAc-PI de-N-acetylase
OKBOLDLM_03445 2.4e-141 C WbqC-like protein family
OKBOLDLM_03446 2.4e-140 M Protein involved in cellulose biosynthesis
OKBOLDLM_03447 1.3e-219 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OKBOLDLM_03448 1.4e-167 5.1.3.2 M GDP-mannose 4,6 dehydratase
OKBOLDLM_03449 7.6e-216 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
OKBOLDLM_03450 9.5e-250 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OKBOLDLM_03451 7.3e-223 ywaD 3.4.11.10, 3.4.11.6 S PA domain
OKBOLDLM_03452 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
OKBOLDLM_03453 6.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
OKBOLDLM_03454 5.6e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
OKBOLDLM_03455 1.6e-216 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
OKBOLDLM_03456 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
OKBOLDLM_03457 8.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
OKBOLDLM_03458 2.3e-31 araE EGP Major facilitator Superfamily
OKBOLDLM_03459 2.8e-211 araE EGP Major facilitator Superfamily
OKBOLDLM_03460 6.7e-201 araR K transcriptional
OKBOLDLM_03461 1.2e-188 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OKBOLDLM_03462 1.1e-13 yvbU K Transcriptional regulator
OKBOLDLM_03463 1.7e-96 yvbU K Transcriptional regulator
OKBOLDLM_03464 8.2e-152 yvbV EG EamA-like transporter family
OKBOLDLM_03465 3.2e-213 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
OKBOLDLM_03467 6.7e-148 ybbH_1 K RpiR family transcriptional regulator
OKBOLDLM_03468 6.6e-295 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
OKBOLDLM_03469 2.3e-219 gntP EG COG2610 H gluconate symporter and related permeases
OKBOLDLM_03470 3.5e-129 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
OKBOLDLM_03471 1.7e-265 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
OKBOLDLM_03472 1.8e-133 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
OKBOLDLM_03473 2.1e-208 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OKBOLDLM_03474 1.4e-117 yvfI K COG2186 Transcriptional regulators
OKBOLDLM_03475 3.8e-296 yvfH C L-lactate permease
OKBOLDLM_03476 8.8e-232 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
OKBOLDLM_03477 2.7e-32 yvfG S YvfG protein
OKBOLDLM_03478 2.3e-176 yvfF GM Exopolysaccharide biosynthesis protein
OKBOLDLM_03479 2.7e-216 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
OKBOLDLM_03480 1.1e-49 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
OKBOLDLM_03481 1.8e-102 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
OKBOLDLM_03482 5.2e-268 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OKBOLDLM_03483 2e-186 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
OKBOLDLM_03484 2e-197 epsI GM pyruvyl transferase
OKBOLDLM_03485 4.6e-191 epsH GT2 S Glycosyltransferase like family 2
OKBOLDLM_03486 1.4e-201 epsG S EpsG family
OKBOLDLM_03487 1.1e-198 epsF GT4 M Glycosyl transferases group 1
OKBOLDLM_03488 8.6e-156 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OKBOLDLM_03489 3.6e-213 epsD GT4 M Glycosyl transferase 4-like
OKBOLDLM_03490 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
OKBOLDLM_03491 2.1e-112 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
OKBOLDLM_03492 3.3e-116 ywqC M biosynthesis protein
OKBOLDLM_03493 5.1e-78 slr K transcriptional
OKBOLDLM_03494 6.5e-236 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
OKBOLDLM_03496 1.3e-85 ywjB H RibD C-terminal domain
OKBOLDLM_03497 1.7e-130 CH FAD binding domain
OKBOLDLM_03498 9.3e-74 S Metallo-beta-lactamase superfamily
OKBOLDLM_03499 3e-105 yyaS S Membrane
OKBOLDLM_03500 1e-82 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OKBOLDLM_03501 1.2e-93 padC Q Phenolic acid decarboxylase
OKBOLDLM_03502 9.4e-50 MA20_18690 S Protein of unknown function (DUF3237)
OKBOLDLM_03503 6.1e-31 S Protein of unknown function (DUF1433)
OKBOLDLM_03504 5e-17 S Protein of unknown function (DUF1433)
OKBOLDLM_03505 4.8e-19 S Protein of unknown function (DUF1433)
OKBOLDLM_03506 1.8e-126 I Pfam Lipase (class 3)
OKBOLDLM_03507 1.7e-97 I Pfam Lipase (class 3)
OKBOLDLM_03508 7.6e-33
OKBOLDLM_03510 2.8e-279 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
OKBOLDLM_03511 7.8e-214 rafB P LacY proton/sugar symporter
OKBOLDLM_03512 4.6e-177 scrR K transcriptional
OKBOLDLM_03513 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
OKBOLDLM_03514 7.2e-158 yraN K Transcriptional regulator
OKBOLDLM_03515 3.7e-202 yraM S PrpF protein
OKBOLDLM_03516 8.3e-241 EGP Sugar (and other) transporter
OKBOLDLM_03517 5.3e-89
OKBOLDLM_03518 6.4e-102 yvdD 3.2.2.10 S Belongs to the LOG family
OKBOLDLM_03519 7.1e-50 yvdC S MazG nucleotide pyrophosphohydrolase domain
OKBOLDLM_03520 2.6e-270 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
OKBOLDLM_03521 4.1e-104 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
OKBOLDLM_03522 2.9e-179 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OKBOLDLM_03523 1.3e-76 M Ribonuclease
OKBOLDLM_03524 1.5e-130 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
OKBOLDLM_03525 1.4e-35 crh G Phosphocarrier protein Chr
OKBOLDLM_03526 3.1e-170 whiA K May be required for sporulation
OKBOLDLM_03527 3.2e-175 ybhK S Required for morphogenesis under gluconeogenic growth conditions
OKBOLDLM_03528 3.3e-166 rapZ S Displays ATPase and GTPase activities
OKBOLDLM_03529 8.5e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
OKBOLDLM_03530 5.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
OKBOLDLM_03531 2.1e-117 usp CBM50 M protein conserved in bacteria
OKBOLDLM_03532 4.2e-267 S COG0457 FOG TPR repeat
OKBOLDLM_03533 6.8e-182 sasA T Histidine kinase
OKBOLDLM_03534 4.4e-118 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OKBOLDLM_03535 0.0 msbA2 3.6.3.44 V ABC transporter
OKBOLDLM_03536 2.2e-108 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
OKBOLDLM_03537 1.2e-135 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
OKBOLDLM_03538 6.7e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OKBOLDLM_03539 1.4e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OKBOLDLM_03540 8.2e-105 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
OKBOLDLM_03541 1.7e-219 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OKBOLDLM_03542 1.4e-113 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
OKBOLDLM_03543 9.4e-201 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
OKBOLDLM_03544 7.2e-135 yvpB NU protein conserved in bacteria
OKBOLDLM_03545 2.4e-79 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
OKBOLDLM_03546 1.3e-111 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
OKBOLDLM_03547 3.4e-149 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OKBOLDLM_03548 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OKBOLDLM_03549 3.4e-214 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
OKBOLDLM_03550 4.1e-130 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
OKBOLDLM_03551 7.6e-132 yvoA K transcriptional
OKBOLDLM_03552 3.2e-101 yxaF K Transcriptional regulator
OKBOLDLM_03553 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
OKBOLDLM_03554 9.1e-46 yvlD S Membrane
OKBOLDLM_03555 9.6e-26 pspB KT PspC domain
OKBOLDLM_03556 5.6e-163 yvlB S Putative adhesin
OKBOLDLM_03557 4e-46 yvlA
OKBOLDLM_03558 3.6e-30 yvkN
OKBOLDLM_03559 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
OKBOLDLM_03560 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
OKBOLDLM_03561 7.6e-33 csbA S protein conserved in bacteria
OKBOLDLM_03562 0.0 yvkC 2.7.9.2 GT Phosphotransferase
OKBOLDLM_03563 1e-91 yvkB K Transcriptional regulator
OKBOLDLM_03564 6.5e-222 yvkA EGP Major facilitator Superfamily
OKBOLDLM_03565 4.5e-25 yuaB
OKBOLDLM_03567 1.1e-217 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OKBOLDLM_03568 2.9e-54 swrA S Swarming motility protein
OKBOLDLM_03569 3.8e-249 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
OKBOLDLM_03570 6.9e-190 ywoF P Right handed beta helix region
OKBOLDLM_03571 1.2e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
OKBOLDLM_03572 2.3e-122 ftsE D cell division ATP-binding protein FtsE
OKBOLDLM_03573 5.2e-35 cccB C COG2010 Cytochrome c, mono- and diheme variants
OKBOLDLM_03574 1.5e-147 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
OKBOLDLM_03575 9.4e-170 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
OKBOLDLM_03576 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
OKBOLDLM_03577 4.5e-100 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OKBOLDLM_03578 6.8e-68
OKBOLDLM_03579 1.3e-09 fliT S bacterial-type flagellum organization
OKBOLDLM_03580 7e-63 fliS N flagellar protein FliS
OKBOLDLM_03581 9.5e-238 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
OKBOLDLM_03582 1.9e-101 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OKBOLDLM_03583 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
OKBOLDLM_03584 8.5e-75 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
OKBOLDLM_03585 8.3e-78 yviE
OKBOLDLM_03586 7.4e-161 flgL N Belongs to the bacterial flagellin family
OKBOLDLM_03587 2.2e-271 flgK N flagellar hook-associated protein
OKBOLDLM_03588 5.4e-78 flgN NOU FlgN protein
OKBOLDLM_03589 2.3e-38 flgM KNU Negative regulator of flagellin synthesis
OKBOLDLM_03590 3.9e-72 yvyF S flagellar protein
OKBOLDLM_03591 6.2e-62 comFC S Phosphoribosyl transferase domain
OKBOLDLM_03592 8.2e-42 comFB S Late competence development protein ComFB
OKBOLDLM_03593 3.2e-248 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
OKBOLDLM_03594 8.1e-154 degV S protein conserved in bacteria
OKBOLDLM_03595 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OKBOLDLM_03596 3.4e-179 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
OKBOLDLM_03597 1e-116 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
OKBOLDLM_03598 4.2e-170 yvhJ K Transcriptional regulator
OKBOLDLM_03599 1.4e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
OKBOLDLM_03600 5.6e-225 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
OKBOLDLM_03601 1.9e-141 tuaG GT2 M Glycosyltransferase like family 2
OKBOLDLM_03602 1.6e-107 tuaF M protein involved in exopolysaccharide biosynthesis
OKBOLDLM_03603 5.4e-251 tuaE M Teichuronic acid biosynthesis protein
OKBOLDLM_03604 1.5e-242 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OKBOLDLM_03605 1.4e-212 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
OKBOLDLM_03606 4.8e-255 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OKBOLDLM_03607 1.4e-116 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
OKBOLDLM_03608 6.7e-212 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OKBOLDLM_03609 1.1e-303 lytB 3.5.1.28 D Stage II sporulation protein
OKBOLDLM_03610 1e-29
OKBOLDLM_03611 5.2e-138 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
OKBOLDLM_03612 1.2e-184 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
OKBOLDLM_03613 2.1e-157 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
OKBOLDLM_03614 1e-178 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
OKBOLDLM_03615 3.4e-136 tagG GM Transport permease protein
OKBOLDLM_03616 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OKBOLDLM_03617 1.3e-258 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
OKBOLDLM_03618 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
OKBOLDLM_03619 1.4e-139 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
OKBOLDLM_03620 7.6e-203 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OKBOLDLM_03621 1.5e-214 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
OKBOLDLM_03622 3.8e-184 pmi 5.3.1.8 G mannose-6-phosphate isomerase
OKBOLDLM_03623 3.2e-251 gerBA EG Spore germination protein
OKBOLDLM_03624 1.4e-190 gerBB E Spore germination protein
OKBOLDLM_03625 1.7e-171 gerAC S Spore germination protein
OKBOLDLM_03626 4.4e-258 GT2,GT4 J Glycosyl transferase family 2
OKBOLDLM_03627 1.6e-239 ywtG EGP Major facilitator Superfamily
OKBOLDLM_03628 1.1e-173 ywtF K Transcriptional regulator
OKBOLDLM_03629 1.4e-153 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
OKBOLDLM_03630 4.1e-29 yttA 2.7.13.3 S Pfam Transposase IS66
OKBOLDLM_03631 8.6e-229 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
OKBOLDLM_03632 1.2e-18 ywtC
OKBOLDLM_03633 1.2e-216 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
OKBOLDLM_03634 2.3e-70 pgsC S biosynthesis protein
OKBOLDLM_03635 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
OKBOLDLM_03636 1.2e-184 gerKA EG Spore germination protein
OKBOLDLM_03637 2.1e-178 gerKB E Spore germination protein
OKBOLDLM_03638 3.1e-50 gerKC S Spore germination B3/ GerAC like, C-terminal
OKBOLDLM_03639 4.4e-113 gerKC S Spore germination B3/ GerAC like, C-terminal
OKBOLDLM_03640 3.7e-174 rbsR K transcriptional
OKBOLDLM_03641 6.5e-154 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OKBOLDLM_03642 9e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
OKBOLDLM_03643 8.4e-271 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
OKBOLDLM_03644 3.5e-153 rbsC G Belongs to the binding-protein-dependent transport system permease family
OKBOLDLM_03645 3.1e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
OKBOLDLM_03646 3.9e-85 batE T Sh3 type 3 domain protein
OKBOLDLM_03647 7.5e-89 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
OKBOLDLM_03648 9e-144 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
OKBOLDLM_03649 9.6e-303 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
OKBOLDLM_03650 7.1e-164 alsR K LysR substrate binding domain
OKBOLDLM_03651 1.1e-232 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OKBOLDLM_03652 1.2e-115 ywrJ
OKBOLDLM_03653 1.5e-113 cotB
OKBOLDLM_03654 8.5e-204 cotH M Spore Coat
OKBOLDLM_03655 1.1e-06
OKBOLDLM_03656 6.2e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OKBOLDLM_03658 1.6e-291 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
OKBOLDLM_03659 3e-81 ywrC K Transcriptional regulator
OKBOLDLM_03660 2e-98 ywrB P Chromate transporter
OKBOLDLM_03661 1.9e-87 ywrA P COG2059 Chromate transport protein ChrA
OKBOLDLM_03662 3.3e-102
OKBOLDLM_03663 4.9e-63
OKBOLDLM_03664 1.3e-73 S SMI1 / KNR4 family
OKBOLDLM_03665 3.6e-18
OKBOLDLM_03666 8.4e-59 S SUKH-4 immunity protein
OKBOLDLM_03667 1.4e-230 ywqJ S Pre-toxin TG
OKBOLDLM_03668 1.4e-35 ywqI S Family of unknown function (DUF5344)
OKBOLDLM_03669 1.3e-17 S Domain of unknown function (DUF5082)
OKBOLDLM_03670 4.2e-144 ywqG S Domain of unknown function (DUF1963)
OKBOLDLM_03671 4e-240 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OKBOLDLM_03672 8.2e-137 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
OKBOLDLM_03673 8.5e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
OKBOLDLM_03674 1.2e-105 ywqC M biosynthesis protein
OKBOLDLM_03675 2.6e-15
OKBOLDLM_03676 2.9e-301 ywqB S SWIM zinc finger
OKBOLDLM_03677 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
OKBOLDLM_03678 7.2e-150 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
OKBOLDLM_03679 1.2e-135 glcR K DeoR C terminal sensor domain
OKBOLDLM_03680 5.4e-56 ssbB L Single-stranded DNA-binding protein
OKBOLDLM_03681 2.5e-56 ywpG
OKBOLDLM_03682 9.9e-68 ywpF S YwpF-like protein
OKBOLDLM_03683 5.9e-46 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
OKBOLDLM_03684 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
OKBOLDLM_03685 1.1e-192 S aspartate phosphatase
OKBOLDLM_03686 1.5e-136 flhP N flagellar basal body
OKBOLDLM_03687 8e-127 flhO N flagellar basal body
OKBOLDLM_03688 2.7e-180 mbl D Rod shape-determining protein
OKBOLDLM_03689 1.8e-44 spoIIID K Stage III sporulation protein D
OKBOLDLM_03690 1.1e-71 ywoH K transcriptional
OKBOLDLM_03691 4.1e-212 ywoG EGP Major facilitator Superfamily
OKBOLDLM_03692 2.4e-270 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
OKBOLDLM_03693 9.8e-242 ywoD EGP Major facilitator superfamily
OKBOLDLM_03694 8.5e-99 phzA Q Isochorismatase family
OKBOLDLM_03695 3.9e-226 amt P Ammonium transporter
OKBOLDLM_03696 1.7e-57 nrgB K Belongs to the P(II) protein family
OKBOLDLM_03697 1.1e-206 ftsW D Belongs to the SEDS family
OKBOLDLM_03698 1.3e-99 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
OKBOLDLM_03699 6.4e-67 ywnJ S VanZ like family
OKBOLDLM_03700 2.7e-120 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
OKBOLDLM_03701 3.9e-87 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
OKBOLDLM_03702 3.1e-11 ywnC S Family of unknown function (DUF5362)
OKBOLDLM_03703 1.3e-67 ywnF S Family of unknown function (DUF5392)
OKBOLDLM_03704 1.2e-274 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OKBOLDLM_03705 8.6e-16 yqgA
OKBOLDLM_03706 1.3e-50 ywnC S Family of unknown function (DUF5362)
OKBOLDLM_03707 3.7e-90 ywnB S NAD(P)H-binding
OKBOLDLM_03708 6.1e-67 ywnA K Transcriptional regulator
OKBOLDLM_03709 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
OKBOLDLM_03710 5.5e-62 ureB 3.5.1.5 E Belongs to the urease beta subunit family
OKBOLDLM_03711 2e-49 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
OKBOLDLM_03712 5.3e-09 csbD K CsbD-like
OKBOLDLM_03713 1.2e-80 ywmF S Peptidase M50
OKBOLDLM_03714 8.2e-93 S response regulator aspartate phosphatase
OKBOLDLM_03715 3.8e-190 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OKBOLDLM_03716 1e-142 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OKBOLDLM_03718 8.1e-120 ywmD S protein containing a von Willebrand factor type A (vWA) domain
OKBOLDLM_03719 1.3e-112 ywmC S protein containing a von Willebrand factor type A (vWA) domain
OKBOLDLM_03720 1.2e-180 spoIID D Stage II sporulation protein D
OKBOLDLM_03721 8.2e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OKBOLDLM_03722 1.4e-130 ywmB S TATA-box binding
OKBOLDLM_03723 6.2e-32 ywzB S membrane
OKBOLDLM_03724 4.3e-88 ywmA
OKBOLDLM_03725 5.3e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
OKBOLDLM_03726 1e-265 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OKBOLDLM_03727 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OKBOLDLM_03728 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OKBOLDLM_03729 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OKBOLDLM_03730 3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OKBOLDLM_03731 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OKBOLDLM_03732 5.4e-130 atpB C it plays a direct role in the translocation of protons across the membrane
OKBOLDLM_03733 2.8e-61 atpI S ATP synthase
OKBOLDLM_03734 4e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OKBOLDLM_03735 9.6e-236 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OKBOLDLM_03736 3.2e-95 ywlG S Belongs to the UPF0340 family
OKBOLDLM_03737 4.6e-79 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
OKBOLDLM_03738 1.1e-72 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OKBOLDLM_03739 2.4e-85 mntP P Probably functions as a manganese efflux pump
OKBOLDLM_03740 3.8e-185 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
OKBOLDLM_03741 3.7e-73 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
OKBOLDLM_03742 9.2e-116 spoIIR S stage II sporulation protein R
OKBOLDLM_03743 9.7e-59 ywlA S Uncharacterised protein family (UPF0715)
OKBOLDLM_03745 6.5e-151 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
OKBOLDLM_03746 2.6e-189 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OKBOLDLM_03747 2.4e-65 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OKBOLDLM_03748 2.7e-89 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
OKBOLDLM_03749 1.1e-151 ywkB S Membrane transport protein
OKBOLDLM_03750 0.0 sfcA 1.1.1.38 C malic enzyme
OKBOLDLM_03751 5.6e-101 tdk 2.7.1.21 F thymidine kinase
OKBOLDLM_03752 1.1e-32 rpmE J Binds the 23S rRNA
OKBOLDLM_03753 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OKBOLDLM_03754 1.1e-173 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
OKBOLDLM_03755 3.3e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OKBOLDLM_03756 7.1e-110 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OKBOLDLM_03757 2.7e-157 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
OKBOLDLM_03758 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
OKBOLDLM_03759 1.8e-90 ywjG S Domain of unknown function (DUF2529)
OKBOLDLM_03760 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
OKBOLDLM_03761 7.1e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
OKBOLDLM_03762 0.0 fadF C COG0247 Fe-S oxidoreductase
OKBOLDLM_03763 1.1e-201 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
OKBOLDLM_03764 2.1e-174 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
OKBOLDLM_03765 9.3e-43 ywjC
OKBOLDLM_03766 0.0 ywjA V ABC transporter
OKBOLDLM_03767 2.7e-288 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OKBOLDLM_03768 1.4e-116 narI 1.7.5.1 C nitrate reductase, gamma
OKBOLDLM_03769 4e-85 narJ 1.7.5.1 C nitrate reductase
OKBOLDLM_03770 3.8e-292 narH 1.7.5.1 C Nitrate reductase, beta
OKBOLDLM_03771 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OKBOLDLM_03772 1.4e-78 arfM T cyclic nucleotide binding
OKBOLDLM_03773 3.6e-77 ywiC S YwiC-like protein
OKBOLDLM_03774 1.4e-125 fnr K helix_turn_helix, cAMP Regulatory protein
OKBOLDLM_03775 4.3e-209 narK P COG2223 Nitrate nitrite transporter
OKBOLDLM_03776 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
OKBOLDLM_03777 1.5e-71 ywiB S protein conserved in bacteria
OKBOLDLM_03779 1.2e-189 ywhL CO amine dehydrogenase activity
OKBOLDLM_03780 5.8e-78 S aspartate phosphatase
OKBOLDLM_03782 2.3e-167 speB 3.5.3.11 E Belongs to the arginase family
OKBOLDLM_03783 1.6e-157 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OKBOLDLM_03784 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
OKBOLDLM_03785 3e-72
OKBOLDLM_03786 5.1e-90 ywhD S YwhD family
OKBOLDLM_03787 8.1e-117 ywhC S Peptidase family M50
OKBOLDLM_03788 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
OKBOLDLM_03789 9.8e-68 ywhA K Transcriptional regulator
OKBOLDLM_03790 4.9e-241 yhdG_1 E C-terminus of AA_permease
OKBOLDLM_03791 1.7e-87 ywgA 2.1.1.72, 3.1.21.3
OKBOLDLM_03792 9e-253 ywfO S COG1078 HD superfamily phosphohydrolases
OKBOLDLM_03793 6.9e-36 ywzC S Belongs to the UPF0741 family
OKBOLDLM_03794 1.6e-103 rsfA_1
OKBOLDLM_03795 4.1e-50 padR K PadR family transcriptional regulator
OKBOLDLM_03796 4e-85 S membrane
OKBOLDLM_03797 2.2e-152 V ABC transporter, ATP-binding protein
OKBOLDLM_03798 1.1e-162 yhcI S ABC transporter (permease)
OKBOLDLM_03801 4.2e-164
OKBOLDLM_03803 2e-155 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
OKBOLDLM_03804 1.3e-154 cysL K Transcriptional regulator
OKBOLDLM_03805 6.7e-152 MA20_14895 S Conserved hypothetical protein 698
OKBOLDLM_03806 8.1e-174 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
OKBOLDLM_03807 4.8e-145 ywfI C May function as heme-dependent peroxidase
OKBOLDLM_03808 1.3e-14 K Helix-turn-helix XRE-family like proteins
OKBOLDLM_03810 8.9e-139 IQ Enoyl-(Acyl carrier protein) reductase
OKBOLDLM_03811 4.9e-229 ywfG 2.6.1.83 E Aminotransferase class I and II
OKBOLDLM_03812 6.1e-208 bacE EGP Major facilitator Superfamily
OKBOLDLM_03813 8e-263 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
OKBOLDLM_03814 3.3e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OKBOLDLM_03815 1.1e-135 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
OKBOLDLM_03816 1.4e-110 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
OKBOLDLM_03817 5.8e-217 ywfA EGP Major facilitator Superfamily
OKBOLDLM_03818 8.8e-170 tcaB EGP Major facilitator Superfamily
OKBOLDLM_03819 4.2e-256 lysP E amino acid
OKBOLDLM_03820 0.0 rocB E arginine degradation protein
OKBOLDLM_03821 3.6e-293 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
OKBOLDLM_03822 1.1e-245 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
OKBOLDLM_03823 2.6e-61
OKBOLDLM_03824 1.3e-84 spsL 5.1.3.13 M Spore Coat
OKBOLDLM_03825 5.6e-155 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
OKBOLDLM_03826 1e-176 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
OKBOLDLM_03827 4.5e-132 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
OKBOLDLM_03828 1.3e-166 spsG M Spore Coat
OKBOLDLM_03829 2.6e-124 spsF M Spore Coat
OKBOLDLM_03830 1.4e-209 spsE 2.5.1.56 M acid synthase
OKBOLDLM_03831 6.6e-151 spsD 2.3.1.210 K Spore Coat
OKBOLDLM_03832 1e-215 spsC E Belongs to the DegT DnrJ EryC1 family
OKBOLDLM_03833 2.7e-258 spsB M Capsule polysaccharide biosynthesis protein
OKBOLDLM_03834 9.4e-141 spsA M Spore Coat
OKBOLDLM_03835 1.6e-62 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
OKBOLDLM_03836 5e-55 ywdK S small membrane protein
OKBOLDLM_03837 5.6e-226 ywdJ F Xanthine uracil
OKBOLDLM_03838 5.4e-36 ywdI S Family of unknown function (DUF5327)
OKBOLDLM_03839 5.4e-132 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OKBOLDLM_03840 9.2e-147 ywdF GT2,GT4 S Glycosyltransferase like family 2
OKBOLDLM_03842 1.9e-144 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
OKBOLDLM_03843 1.5e-20 ywdA
OKBOLDLM_03844 1.7e-268 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
OKBOLDLM_03845 7.8e-247 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OKBOLDLM_03846 1.3e-148 sacT K transcriptional antiterminator
OKBOLDLM_03848 0.0 vpr O Belongs to the peptidase S8 family
OKBOLDLM_03849 6.4e-182 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OKBOLDLM_03850 2.7e-118 M1-869 K WYL domain
OKBOLDLM_03851 4e-126 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OKBOLDLM_03852 3.2e-42 S Ketosteroid isomerase-related protein
OKBOLDLM_03853 2.1e-32 S Stress responsive A/B Barrel Domain
OKBOLDLM_03854 6.8e-136 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
OKBOLDLM_03855 1.8e-207 rodA D Belongs to the SEDS family
OKBOLDLM_03856 6.3e-68 ysnE K acetyltransferase
OKBOLDLM_03857 3.9e-31 ywcE S Required for proper spore morphogenesis. Important for spore germination
OKBOLDLM_03858 1.6e-61 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
OKBOLDLM_03859 2.3e-110 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
OKBOLDLM_03860 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OKBOLDLM_03861 1.6e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
OKBOLDLM_03862 8.4e-27 ywzA S membrane
OKBOLDLM_03863 6.4e-282 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
OKBOLDLM_03864 2.1e-208 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OKBOLDLM_03865 9.6e-60 gtcA S GtrA-like protein
OKBOLDLM_03866 1.1e-96 ywcC K Bacterial regulatory proteins, tetR family
OKBOLDLM_03868 8.3e-125 H Methionine biosynthesis protein MetW
OKBOLDLM_03869 6.8e-119 S Streptomycin biosynthesis protein StrF
OKBOLDLM_03870 6.3e-108 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
OKBOLDLM_03871 2.9e-232 ywbN P Dyp-type peroxidase family protein
OKBOLDLM_03872 2.4e-132 ycdO P periplasmic lipoprotein involved in iron transport
OKBOLDLM_03873 1.1e-193 P COG0672 High-affinity Fe2 Pb2 permease
OKBOLDLM_03874 1.8e-108 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
OKBOLDLM_03875 4.8e-127 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
OKBOLDLM_03876 2.6e-150 ywbI K Transcriptional regulator
OKBOLDLM_03877 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
OKBOLDLM_03878 2.2e-109 ywbG M effector of murein hydrolase
OKBOLDLM_03879 1.5e-26 ywbE S Uncharacterized conserved protein (DUF2196)
OKBOLDLM_03880 1.8e-128 mta K transcriptional
OKBOLDLM_03881 2.7e-155 yjfC O Predicted Zn-dependent protease (DUF2268)
OKBOLDLM_03882 4.9e-221 ywbD 2.1.1.191 J Methyltransferase
OKBOLDLM_03883 2.9e-66 ywbC 4.4.1.5 E glyoxalase
OKBOLDLM_03884 1.6e-241 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OKBOLDLM_03885 7.8e-252 epr 3.4.21.62 O Belongs to the peptidase S8 family
OKBOLDLM_03886 1.6e-160 gspA M General stress
OKBOLDLM_03888 2.9e-116 ywaC 2.7.6.5 S protein conserved in bacteria
OKBOLDLM_03889 1.9e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
OKBOLDLM_03890 4.7e-12 S D-Ala-teichoic acid biosynthesis protein
OKBOLDLM_03891 9e-289 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OKBOLDLM_03892 6.5e-226 dltB M membrane protein involved in D-alanine export
OKBOLDLM_03893 5.6e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OKBOLDLM_03894 5.6e-193 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
OKBOLDLM_03895 5.5e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
OKBOLDLM_03896 2.3e-248 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
OKBOLDLM_03897 6.2e-49 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
OKBOLDLM_03898 1.2e-244 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OKBOLDLM_03899 7.5e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
OKBOLDLM_03900 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
OKBOLDLM_03901 5.2e-107 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
OKBOLDLM_03902 2.9e-169 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OKBOLDLM_03903 3.3e-178 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OKBOLDLM_03904 2.2e-165 cbrA3 P Periplasmic binding protein
OKBOLDLM_03905 1.2e-50 arsR K transcriptional
OKBOLDLM_03906 3.9e-224 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OKBOLDLM_03907 4.9e-48 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
OKBOLDLM_03908 1.9e-47 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
OKBOLDLM_03909 1.8e-224 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OKBOLDLM_03910 1.8e-278 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OKBOLDLM_03911 1.1e-161 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
OKBOLDLM_03912 1.5e-177 manA 5.3.1.8 G mannose-6-phosphate isomerase
OKBOLDLM_03913 6.9e-206 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
OKBOLDLM_03914 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
OKBOLDLM_03915 2e-189 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
OKBOLDLM_03916 7e-248 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
OKBOLDLM_03917 5.3e-150 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OKBOLDLM_03918 4.8e-286 cydD V ATP-binding protein
OKBOLDLM_03919 6.4e-307 cydD V ATP-binding
OKBOLDLM_03920 5.7e-186 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
OKBOLDLM_03921 3.8e-265 cydA 1.10.3.14 C oxidase, subunit
OKBOLDLM_03922 2.3e-211 cimH C COG3493 Na citrate symporter
OKBOLDLM_03923 1.2e-149 yxkH G Polysaccharide deacetylase
OKBOLDLM_03924 1.5e-203 msmK P Belongs to the ABC transporter superfamily
OKBOLDLM_03925 2e-155 lrp QT PucR C-terminal helix-turn-helix domain
OKBOLDLM_03926 6.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
OKBOLDLM_03928 9.7e-83 yxkC S Domain of unknown function (DUF4352)
OKBOLDLM_03929 2.6e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
OKBOLDLM_03930 2.6e-233 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
OKBOLDLM_03933 3e-81 yxjI S LURP-one-related
OKBOLDLM_03934 9.4e-214 yxjG 2.1.1.14 E Methionine synthase
OKBOLDLM_03935 1.8e-143 rlmA 2.1.1.187 Q Methyltransferase domain
OKBOLDLM_03936 6.8e-208 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OKBOLDLM_03937 6e-67 T Domain of unknown function (DUF4163)
OKBOLDLM_03938 2.8e-45 yxiS
OKBOLDLM_03939 6.4e-181 L DNA synthesis involved in DNA repair
OKBOLDLM_03940 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
OKBOLDLM_03941 6.8e-221 citH C Citrate transporter
OKBOLDLM_03942 3.8e-136 exoK GH16 M licheninase activity
OKBOLDLM_03943 1.8e-142 licT K transcriptional antiterminator
OKBOLDLM_03944 1.6e-219 yxiO S COG2270 Permeases of the major facilitator superfamily
OKBOLDLM_03945 3.4e-253 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
OKBOLDLM_03947 1.4e-21
OKBOLDLM_03948 5.8e-14 S YxiJ-like protein
OKBOLDLM_03949 3.9e-111
OKBOLDLM_03950 5.6e-77
OKBOLDLM_03951 9.9e-65 yxiG
OKBOLDLM_03952 2.6e-57 yxxG
OKBOLDLM_03954 2.2e-196 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
OKBOLDLM_03955 1.5e-142 yxxF EG EamA-like transporter family
OKBOLDLM_03956 4.1e-72 yxiE T Belongs to the universal stress protein A family
OKBOLDLM_03957 1.1e-275 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OKBOLDLM_03958 6.8e-307 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OKBOLDLM_03959 1.7e-46 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
OKBOLDLM_03960 2e-146 dcm 2.1.1.37 L C-5 cytosine-specific DNA methylase
OKBOLDLM_03961 9.7e-163 L Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
OKBOLDLM_03962 2e-262 L Z1 domain
OKBOLDLM_03963 3.4e-82 S Putative PD-(D/E)XK family member, (DUF4420)
OKBOLDLM_03964 9.7e-197 S AIPR protein
OKBOLDLM_03965 3.4e-266 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
OKBOLDLM_03966 8.5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
OKBOLDLM_03967 1.1e-281 hutH 4.3.1.3 E Histidine ammonia-lyase
OKBOLDLM_03968 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OKBOLDLM_03969 9.4e-231 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
OKBOLDLM_03970 1e-168 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
OKBOLDLM_03971 4.3e-248 lysP E amino acid
OKBOLDLM_03972 3.3e-231 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
OKBOLDLM_03973 3.4e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OKBOLDLM_03974 9.4e-113 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OKBOLDLM_03975 5.3e-170 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
OKBOLDLM_03976 2.1e-146 yidA S hydrolases of the HAD superfamily
OKBOLDLM_03981 7.9e-21 yxeD
OKBOLDLM_03982 2.7e-35
OKBOLDLM_03983 1.2e-169 fhuD P Periplasmic binding protein
OKBOLDLM_03984 2.7e-55 yxeA S Protein of unknown function (DUF1093)
OKBOLDLM_03985 0.0 yxdM V ABC transporter (permease)
OKBOLDLM_03986 1.4e-136 yxdL V ABC transporter, ATP-binding protein
OKBOLDLM_03987 9.6e-175 T PhoQ Sensor
OKBOLDLM_03988 3e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OKBOLDLM_03989 4.6e-152 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
OKBOLDLM_03990 1.4e-145 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
OKBOLDLM_03991 6.8e-164 iolH G Xylose isomerase-like TIM barrel
OKBOLDLM_03992 1.4e-121 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
OKBOLDLM_03993 5.2e-47 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
OKBOLDLM_03994 2e-228 iolF EGP Major facilitator Superfamily
OKBOLDLM_03995 1.8e-172 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
OKBOLDLM_03996 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
OKBOLDLM_03997 4.7e-177 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
OKBOLDLM_03998 8.7e-153 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
OKBOLDLM_03999 3e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OKBOLDLM_04000 8.9e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
OKBOLDLM_04001 4.4e-169 iolS C Aldo keto reductase
OKBOLDLM_04002 4.8e-244 csbC EGP Major facilitator Superfamily
OKBOLDLM_04003 0.0 htpG O Molecular chaperone. Has ATPase activity
OKBOLDLM_04004 2.5e-147 IQ Enoyl-(Acyl carrier protein) reductase
OKBOLDLM_04005 1.6e-100 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OKBOLDLM_04006 3.5e-192 desK 2.7.13.3 T Histidine kinase
OKBOLDLM_04007 1.2e-194 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
OKBOLDLM_04008 1.4e-209 yxbF K Bacterial regulatory proteins, tetR family
OKBOLDLM_04009 4.9e-246 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
OKBOLDLM_04010 3.2e-138 S PQQ-like domain
OKBOLDLM_04011 2.7e-57 S Family of unknown function (DUF5391)
OKBOLDLM_04012 4.3e-49 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
OKBOLDLM_04013 1.1e-198 EGP Major facilitator Superfamily
OKBOLDLM_04014 2.2e-65 yxaI S membrane protein domain
OKBOLDLM_04015 6e-65 E Ring-cleavage extradiol dioxygenase
OKBOLDLM_04016 3.6e-43 E Ring-cleavage extradiol dioxygenase
OKBOLDLM_04017 9.4e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
OKBOLDLM_04018 8.9e-284 ahpF O Alkyl hydroperoxide reductase
OKBOLDLM_04019 9e-186 G Major royal jelly protein
OKBOLDLM_04020 1e-235 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
OKBOLDLM_04021 3.4e-156 K helix_turn_helix, Deoxyribose operon repressor
OKBOLDLM_04022 1.4e-73 K Integron-associated effector binding protein
OKBOLDLM_04023 5.4e-75 yjhE S Phage tail protein
OKBOLDLM_04024 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
OKBOLDLM_04025 3.2e-78 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
OKBOLDLM_04026 4.9e-143 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
OKBOLDLM_04027 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
OKBOLDLM_04028 1.6e-82 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
OKBOLDLM_04029 3.3e-90 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
OKBOLDLM_04030 1.2e-52 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
OKBOLDLM_04031 5.2e-155 S Fusaric acid resistance protein-like
OKBOLDLM_04032 6.5e-19
OKBOLDLM_04033 8.1e-290 3.6.4.12 L AAA domain
OKBOLDLM_04034 0.0 L AAA ATPase domain
OKBOLDLM_04035 2e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OKBOLDLM_04036 7.9e-08 S YyzF-like protein
OKBOLDLM_04039 2.3e-207 yycP
OKBOLDLM_04040 1.9e-130 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
OKBOLDLM_04041 9.3e-178 C oxidoreductases (related to aryl-alcohol dehydrogenases)
OKBOLDLM_04042 1.4e-81 yycN 2.3.1.128 K Acetyltransferase
OKBOLDLM_04044 1.5e-189 S Histidine kinase
OKBOLDLM_04045 8.2e-165 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
OKBOLDLM_04046 1.5e-253 rocE E amino acid
OKBOLDLM_04047 8.7e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
OKBOLDLM_04048 1.6e-61 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
OKBOLDLM_04049 1.3e-42 sdpR K transcriptional
OKBOLDLM_04050 4.7e-253 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
OKBOLDLM_04051 8.4e-197 S Major Facilitator Superfamily
OKBOLDLM_04052 3.7e-244 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
OKBOLDLM_04053 6.5e-93 K PFAM response regulator receiver
OKBOLDLM_04054 1.9e-63 S Peptidase propeptide and YPEB domain
OKBOLDLM_04055 3.4e-214 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OKBOLDLM_04056 6.7e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
OKBOLDLM_04057 8.6e-148 yycI S protein conserved in bacteria
OKBOLDLM_04058 8.2e-257 yycH S protein conserved in bacteria
OKBOLDLM_04059 0.0 vicK 2.7.13.3 T Histidine kinase
OKBOLDLM_04060 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OKBOLDLM_04065 3.9e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OKBOLDLM_04066 2.5e-71 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OKBOLDLM_04067 6.1e-252 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
OKBOLDLM_04068 2.2e-25 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
OKBOLDLM_04070 2.3e-16 yycC K YycC-like protein
OKBOLDLM_04071 2.1e-214 M Glycosyltransferase Family 4
OKBOLDLM_04072 5.5e-192 S Ecdysteroid kinase
OKBOLDLM_04073 5.2e-231 S Carbamoyl-phosphate synthase L chain, ATP binding domain
OKBOLDLM_04074 6e-220 M Glycosyltransferase Family 4
OKBOLDLM_04075 1.8e-116 S GlcNAc-PI de-N-acetylase
OKBOLDLM_04076 1.9e-80 KLT COG0515 Serine threonine protein kinase
OKBOLDLM_04077 8.3e-73 rplI J binds to the 23S rRNA
OKBOLDLM_04078 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
OKBOLDLM_04079 2.5e-148 yybS S membrane
OKBOLDLM_04081 4.9e-79 cotF M Spore coat protein
OKBOLDLM_04082 1.2e-64 ydeP3 K Transcriptional regulator
OKBOLDLM_04083 7.3e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
OKBOLDLM_04084 2.5e-150 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
OKBOLDLM_04085 1e-265 sacB 2.4.1.10 GH68 M levansucrase activity
OKBOLDLM_04086 1.5e-302 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
OKBOLDLM_04087 1.1e-108 K FCD domain
OKBOLDLM_04088 1.9e-73 dinB S PFAM DinB family protein
OKBOLDLM_04089 2.2e-139 G Major Facilitator Superfamily
OKBOLDLM_04090 4.2e-54 ypaA S Protein of unknown function (DUF1304)
OKBOLDLM_04091 4.4e-112 drgA C nitroreductase
OKBOLDLM_04092 1.6e-65 ydgJ K Winged helix DNA-binding domain
OKBOLDLM_04093 5.3e-148 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
OKBOLDLM_04094 3.1e-75 yybA 2.3.1.57 K transcriptional
OKBOLDLM_04095 1.8e-70 yjcF S Acetyltransferase (GNAT) domain
OKBOLDLM_04096 3.3e-19 cadC3 K transcriptional
OKBOLDLM_04097 3.8e-103 S Alpha/beta hydrolase family
OKBOLDLM_04098 2e-27
OKBOLDLM_04099 2.8e-67 ynaF
OKBOLDLM_04100 9.1e-167 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
OKBOLDLM_04101 1.6e-213 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
OKBOLDLM_04102 1.3e-149 yyaK S CAAX protease self-immunity
OKBOLDLM_04103 3.5e-236 ydjK G Sugar (and other) transporter
OKBOLDLM_04104 5.4e-65 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OKBOLDLM_04105 6.9e-170 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
OKBOLDLM_04106 1.7e-139 xth 3.1.11.2 L exodeoxyribonuclease III
OKBOLDLM_04107 4.5e-86 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OKBOLDLM_04108 1.2e-95 adaA 3.2.2.21 K Transcriptional regulator
OKBOLDLM_04109 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OKBOLDLM_04110 8.4e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
OKBOLDLM_04111 3.6e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
OKBOLDLM_04112 1.3e-199 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
OKBOLDLM_04113 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OKBOLDLM_04114 2.3e-33 yyzM S protein conserved in bacteria
OKBOLDLM_04115 2.4e-168 yyaD S Membrane
OKBOLDLM_04116 4.5e-57 4.2.1.103 K FR47-like protein
OKBOLDLM_04117 1.1e-107 yyaC S Sporulation protein YyaC
OKBOLDLM_04118 4.3e-147 spo0J K Belongs to the ParB family
OKBOLDLM_04119 2.7e-135 soj D COG1192 ATPases involved in chromosome partitioning
OKBOLDLM_04120 1.1e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
OKBOLDLM_04121 1.5e-124 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
OKBOLDLM_04122 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
OKBOLDLM_04123 8.9e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OKBOLDLM_04124 8.2e-106 jag S single-stranded nucleic acid binding R3H
OKBOLDLM_04125 4.3e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
OKBOLDLM_04126 1.2e-50 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
OKBOLDLM_04127 4.3e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OKBOLDLM_04128 8e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
OKBOLDLM_04129 2.4e-33 yaaA S S4 domain
OKBOLDLM_04130 2.7e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OKBOLDLM_04131 8.1e-38 yaaB S Domain of unknown function (DUF370)
OKBOLDLM_04132 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OKBOLDLM_04133 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OKBOLDLM_04134 3.3e-43 S transposition, DNA-mediated
OKBOLDLM_04135 5.9e-117 S HTH-like domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)