ORF_ID e_value Gene_name EC_number CAZy COGs Description
MLHAACIH_00006 2e-198 3.1.21.3 L Domain of unknown function (DUF4942)
MLHAACIH_00008 1.6e-235
MLHAACIH_00011 0.0 S RNA-directed RNA polymerase activity
MLHAACIH_00012 1.6e-14 L GIY-YIG type nucleases (URI domain)
MLHAACIH_00013 2.6e-94
MLHAACIH_00014 1.1e-33 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MLHAACIH_00016 2.1e-203 S Calcineurin-like phosphoesterase superfamily domain
MLHAACIH_00020 2.2e-173
MLHAACIH_00021 0.0 gp17a S Terminase-like family
MLHAACIH_00022 2.7e-280
MLHAACIH_00023 3.1e-254
MLHAACIH_00024 7.8e-94
MLHAACIH_00025 1.3e-185
MLHAACIH_00026 1.1e-80
MLHAACIH_00027 3.2e-68
MLHAACIH_00029 3.4e-29
MLHAACIH_00030 7.4e-283 L ATPase involved in DNA repair
MLHAACIH_00031 3.6e-08
MLHAACIH_00032 8.1e-235 T Putative serine esterase (DUF676)
MLHAACIH_00033 4.1e-167
MLHAACIH_00034 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MLHAACIH_00035 1.1e-09 S YyzF-like protein
MLHAACIH_00036 3.5e-27
MLHAACIH_00037 3.7e-232 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MLHAACIH_00039 3.3e-20 yycQ S Protein of unknown function (DUF2651)
MLHAACIH_00040 9.6e-206 yycP
MLHAACIH_00041 9.3e-130 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MLHAACIH_00042 1.2e-82 yycN 2.3.1.128 K Acetyltransferase
MLHAACIH_00043 1.5e-187 S aspartate phosphatase
MLHAACIH_00045 2e-166 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
MLHAACIH_00046 2.8e-260 rocE E amino acid
MLHAACIH_00047 7.5e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
MLHAACIH_00048 3.4e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MLHAACIH_00049 1.4e-215 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MLHAACIH_00050 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MLHAACIH_00051 6.2e-154 yycI S protein conserved in bacteria
MLHAACIH_00052 2.6e-258 yycH S protein conserved in bacteria
MLHAACIH_00053 0.0 vicK 2.7.13.3 T Histidine kinase
MLHAACIH_00054 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLHAACIH_00059 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MLHAACIH_00060 1.6e-54 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLHAACIH_00061 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MLHAACIH_00062 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
MLHAACIH_00064 1.9e-15 yycC K YycC-like protein
MLHAACIH_00065 2.7e-219 yeaN P COG2807 Cyanate permease
MLHAACIH_00066 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MLHAACIH_00067 1.9e-72 rplI J binds to the 23S rRNA
MLHAACIH_00068 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MLHAACIH_00069 8.3e-160 yybS S membrane
MLHAACIH_00071 4e-14 cotF M Spore coat protein
MLHAACIH_00072 1.7e-66 ydeP3 K Transcriptional regulator
MLHAACIH_00073 3.3e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
MLHAACIH_00074 2.3e-33
MLHAACIH_00075 3.2e-27
MLHAACIH_00077 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
MLHAACIH_00078 3.7e-110 K TipAS antibiotic-recognition domain
MLHAACIH_00079 2.2e-121
MLHAACIH_00080 8.6e-66 yybH S SnoaL-like domain
MLHAACIH_00081 6.9e-121 yybG S Pentapeptide repeat-containing protein
MLHAACIH_00082 1.1e-101 ynfM EGP Major facilitator Superfamily
MLHAACIH_00083 5.7e-78 S Metallo-beta-lactamase superfamily
MLHAACIH_00084 2.8e-76 yybA 2.3.1.57 K transcriptional
MLHAACIH_00085 4.2e-69 yjcF S Acetyltransferase (GNAT) domain
MLHAACIH_00086 2.7e-95 yyaS S Membrane
MLHAACIH_00087 2.1e-91 yyaR K Acetyltransferase (GNAT) domain
MLHAACIH_00088 1e-65 yyaQ S YjbR
MLHAACIH_00089 6.1e-105 yyaP 1.5.1.3 H RibD C-terminal domain
MLHAACIH_00090 1.1e-243 tetL EGP Major facilitator Superfamily
MLHAACIH_00091 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
MLHAACIH_00092 8e-168 yyaK S CAAX protease self-immunity
MLHAACIH_00093 1.1e-242 EGP Major facilitator superfamily
MLHAACIH_00094 9.3e-90 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
MLHAACIH_00095 1.4e-65 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLHAACIH_00096 8.9e-178 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
MLHAACIH_00097 1.2e-143 xth 3.1.11.2 L exodeoxyribonuclease III
MLHAACIH_00098 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MLHAACIH_00099 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MLHAACIH_00100 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
MLHAACIH_00101 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MLHAACIH_00102 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MLHAACIH_00103 2.3e-33 yyzM S protein conserved in bacteria
MLHAACIH_00104 8.1e-177 yyaD S Membrane
MLHAACIH_00105 1.6e-111 yyaC S Sporulation protein YyaC
MLHAACIH_00106 2.1e-149 spo0J K Belongs to the ParB family
MLHAACIH_00107 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
MLHAACIH_00108 4.1e-72 S Bacterial PH domain
MLHAACIH_00109 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MLHAACIH_00110 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MLHAACIH_00111 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MLHAACIH_00112 1.4e-248 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MLHAACIH_00113 3.2e-107 jag S single-stranded nucleic acid binding R3H
MLHAACIH_00114 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MLHAACIH_00115 6.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MLHAACIH_00116 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MLHAACIH_00117 1.1e-203 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MLHAACIH_00118 2.4e-33 yaaA S S4 domain
MLHAACIH_00119 9.2e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MLHAACIH_00120 1.8e-37 yaaB S Domain of unknown function (DUF370)
MLHAACIH_00121 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MLHAACIH_00122 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MLHAACIH_00123 3.4e-39 S COG NOG14552 non supervised orthologous group
MLHAACIH_00124 4.8e-179 yaaC S YaaC-like Protein
MLHAACIH_00125 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MLHAACIH_00126 7.5e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MLHAACIH_00127 2.8e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MLHAACIH_00128 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MLHAACIH_00129 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MLHAACIH_00130 1.3e-09
MLHAACIH_00131 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
MLHAACIH_00132 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
MLHAACIH_00133 2.1e-209 yaaH M Glycoside Hydrolase Family
MLHAACIH_00134 1.4e-95 yaaI Q COG1335 Amidases related to nicotinamidase
MLHAACIH_00135 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MLHAACIH_00136 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MLHAACIH_00137 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MLHAACIH_00138 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MLHAACIH_00139 7.9e-32 yaaL S Protein of unknown function (DUF2508)
MLHAACIH_00140 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
MLHAACIH_00141 3.4e-31 csfB S Inhibitor of sigma-G Gin
MLHAACIH_00142 2.6e-101 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
MLHAACIH_00143 2.2e-202 yaaN P Belongs to the TelA family
MLHAACIH_00144 4.8e-271 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
MLHAACIH_00145 2e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MLHAACIH_00146 2.2e-54 yaaQ S protein conserved in bacteria
MLHAACIH_00147 1e-70 yaaR S protein conserved in bacteria
MLHAACIH_00148 1.1e-181 holB 2.7.7.7 L DNA polymerase III
MLHAACIH_00149 6.1e-146 yaaT S stage 0 sporulation protein
MLHAACIH_00150 4.8e-31 yabA L Involved in initiation control of chromosome replication
MLHAACIH_00151 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
MLHAACIH_00152 1.5e-49 yazA L endonuclease containing a URI domain
MLHAACIH_00153 4.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MLHAACIH_00154 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
MLHAACIH_00155 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MLHAACIH_00156 1.7e-142 tatD L hydrolase, TatD
MLHAACIH_00157 3.2e-165 rpfB GH23 T protein conserved in bacteria
MLHAACIH_00158 7.9e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MLHAACIH_00159 4.2e-153 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MLHAACIH_00160 1.6e-136 yabG S peptidase
MLHAACIH_00161 7.8e-39 veg S protein conserved in bacteria
MLHAACIH_00162 2e-26 sspF S DNA topological change
MLHAACIH_00163 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MLHAACIH_00164 2.9e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
MLHAACIH_00165 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
MLHAACIH_00166 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MLHAACIH_00167 1.9e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MLHAACIH_00168 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MLHAACIH_00169 4.3e-96 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MLHAACIH_00170 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MLHAACIH_00171 2.4e-39 yabK S Peptide ABC transporter permease
MLHAACIH_00172 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MLHAACIH_00173 1.5e-92 spoVT K stage V sporulation protein
MLHAACIH_00174 7.8e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLHAACIH_00175 3e-244 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MLHAACIH_00176 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MLHAACIH_00177 1.5e-49 yabP S Sporulation protein YabP
MLHAACIH_00178 4.3e-107 yabQ S spore cortex biosynthesis protein
MLHAACIH_00179 1.1e-44 divIC D Septum formation initiator
MLHAACIH_00180 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
MLHAACIH_00183 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
MLHAACIH_00184 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
MLHAACIH_00185 3.7e-185 KLT serine threonine protein kinase
MLHAACIH_00186 3.2e-272 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MLHAACIH_00187 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MLHAACIH_00188 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MLHAACIH_00189 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MLHAACIH_00190 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MLHAACIH_00191 1.3e-151 yacD 5.2.1.8 O peptidyl-prolyl isomerase
MLHAACIH_00192 1.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MLHAACIH_00193 2.2e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MLHAACIH_00194 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
MLHAACIH_00195 1.9e-166 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
MLHAACIH_00196 1.9e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MLHAACIH_00197 2.2e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MLHAACIH_00198 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MLHAACIH_00199 4.1e-30 yazB K transcriptional
MLHAACIH_00200 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MLHAACIH_00201 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MLHAACIH_00202 2.9e-76 ctsR K Belongs to the CtsR family
MLHAACIH_00203 1.7e-57 mcsA 2.7.14.1 S protein with conserved CXXC pairs
MLHAACIH_00204 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MLHAACIH_00205 0.0 clpC O Belongs to the ClpA ClpB family
MLHAACIH_00206 6.2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MLHAACIH_00207 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MLHAACIH_00208 1.7e-196 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
MLHAACIH_00209 4.2e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MLHAACIH_00210 1.2e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MLHAACIH_00211 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MLHAACIH_00212 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
MLHAACIH_00213 2.4e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MLHAACIH_00214 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MLHAACIH_00215 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MLHAACIH_00216 1.2e-88 yacP S RNA-binding protein containing a PIN domain
MLHAACIH_00217 4.4e-115 sigH K Belongs to the sigma-70 factor family
MLHAACIH_00218 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MLHAACIH_00219 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
MLHAACIH_00220 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MLHAACIH_00221 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MLHAACIH_00222 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MLHAACIH_00223 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MLHAACIH_00224 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
MLHAACIH_00225 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MLHAACIH_00226 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MLHAACIH_00227 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
MLHAACIH_00228 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MLHAACIH_00229 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MLHAACIH_00230 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MLHAACIH_00231 8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MLHAACIH_00232 1.7e-184 ybaC 3.4.11.5 S Alpha/beta hydrolase family
MLHAACIH_00233 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
MLHAACIH_00234 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MLHAACIH_00235 3e-105 rplD J Forms part of the polypeptide exit tunnel
MLHAACIH_00236 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MLHAACIH_00237 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MLHAACIH_00238 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MLHAACIH_00239 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MLHAACIH_00240 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MLHAACIH_00241 1.7e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MLHAACIH_00242 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
MLHAACIH_00243 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MLHAACIH_00244 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MLHAACIH_00245 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MLHAACIH_00246 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MLHAACIH_00247 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MLHAACIH_00248 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MLHAACIH_00249 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MLHAACIH_00250 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MLHAACIH_00251 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MLHAACIH_00252 1.9e-23 rpmD J Ribosomal protein L30
MLHAACIH_00253 1.8e-72 rplO J binds to the 23S rRNA
MLHAACIH_00254 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MLHAACIH_00255 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MLHAACIH_00256 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
MLHAACIH_00257 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MLHAACIH_00258 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MLHAACIH_00259 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MLHAACIH_00260 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MLHAACIH_00261 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MLHAACIH_00262 3.6e-58 rplQ J Ribosomal protein L17
MLHAACIH_00263 1.9e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLHAACIH_00264 8.8e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLHAACIH_00265 9.8e-117 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLHAACIH_00266 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MLHAACIH_00267 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MLHAACIH_00268 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
MLHAACIH_00269 1.2e-143 ybaJ Q Methyltransferase domain
MLHAACIH_00270 3.5e-71 ybaK S Protein of unknown function (DUF2521)
MLHAACIH_00271 2.8e-131 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MLHAACIH_00272 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MLHAACIH_00273 1.2e-84 gerD
MLHAACIH_00274 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
MLHAACIH_00275 3.5e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
MLHAACIH_00278 2e-08
MLHAACIH_00283 4.6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
MLHAACIH_00284 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
MLHAACIH_00285 8.6e-139 ybbA S Putative esterase
MLHAACIH_00286 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLHAACIH_00287 4e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLHAACIH_00288 8.3e-163 feuA P Iron-uptake system-binding protein
MLHAACIH_00289 1.4e-303 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
MLHAACIH_00290 1.6e-235 ybbC 3.2.1.52 S protein conserved in bacteria
MLHAACIH_00291 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
MLHAACIH_00292 1.4e-253 yfeW 3.4.16.4 V Belongs to the UPF0214 family
MLHAACIH_00293 8.3e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MLHAACIH_00294 1.2e-149 ybbH K transcriptional
MLHAACIH_00295 2.3e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MLHAACIH_00296 6.3e-60 ybbJ J acetyltransferase
MLHAACIH_00297 1.6e-76 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
MLHAACIH_00303 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
MLHAACIH_00304 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MLHAACIH_00305 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MLHAACIH_00306 8.3e-223 ybbR S protein conserved in bacteria
MLHAACIH_00307 2.3e-251 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MLHAACIH_00308 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MLHAACIH_00309 2.1e-168 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MLHAACIH_00310 7.2e-36 adaA 3.2.2.21 K Transcriptional regulator
MLHAACIH_00311 3e-37 adaA 3.2.2.21 K Transcriptional regulator
MLHAACIH_00312 1.5e-100 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MLHAACIH_00313 6.3e-274 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MLHAACIH_00314 0.0 ybcC S Belongs to the UPF0753 family
MLHAACIH_00315 1.5e-92 can 4.2.1.1 P carbonic anhydrase
MLHAACIH_00317 8.7e-47
MLHAACIH_00318 1.8e-60 ybcI S Uncharacterized conserved protein (DUF2294)
MLHAACIH_00319 5.1e-50 ybzH K Helix-turn-helix domain
MLHAACIH_00320 5.9e-203 ybcL EGP Major facilitator Superfamily
MLHAACIH_00322 9.1e-239 J 4Fe-4S single cluster domain
MLHAACIH_00323 3.3e-275 V CAAX protease self-immunity
MLHAACIH_00324 6.7e-133 skfE V ABC transporter
MLHAACIH_00325 8e-247 skfF S ABC transporter
MLHAACIH_00326 7.8e-91 C HEAT repeats
MLHAACIH_00327 9.6e-79 txn CO Thioredoxin-like
MLHAACIH_00328 2.9e-179 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MLHAACIH_00329 1.3e-122 T Transcriptional regulatory protein, C terminal
MLHAACIH_00330 1.8e-168 T His Kinase A (phospho-acceptor) domain
MLHAACIH_00332 3.9e-139 KLT Protein tyrosine kinase
MLHAACIH_00333 7.7e-152 ybdN
MLHAACIH_00334 3.7e-213 ybdO S Domain of unknown function (DUF4885)
MLHAACIH_00335 2.4e-256 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
MLHAACIH_00336 1.4e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
MLHAACIH_00337 4.9e-30 ybxH S Family of unknown function (DUF5370)
MLHAACIH_00338 3.4e-149 ybxI 3.5.2.6 V beta-lactamase
MLHAACIH_00339 1.3e-243 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
MLHAACIH_00340 4.9e-41 ybyB
MLHAACIH_00341 1.5e-289 ybeC E amino acid
MLHAACIH_00342 2.4e-164 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MLHAACIH_00343 7.3e-258 glpT G -transporter
MLHAACIH_00344 1.6e-33 S Protein of unknown function (DUF2651)
MLHAACIH_00345 2.2e-168 ybfA 3.4.15.5 K FR47-like protein
MLHAACIH_00346 1e-221 ybfB G COG0477 Permeases of the major facilitator superfamily
MLHAACIH_00348 0.0 ybfG M Domain of unknown function (DUF1906)
MLHAACIH_00349 3.7e-160 ybfH EG EamA-like transporter family
MLHAACIH_00350 8.8e-145 msmR K AraC-like ligand binding domain
MLHAACIH_00351 2.9e-210 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MLHAACIH_00352 1.3e-176 mpr 3.4.21.19 M Belongs to the peptidase S1B family
MLHAACIH_00354 4.5e-163 S Alpha/beta hydrolase family
MLHAACIH_00355 7e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MLHAACIH_00356 2.7e-85 ybfM S SNARE associated Golgi protein
MLHAACIH_00357 1.6e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
MLHAACIH_00358 2e-45 ybfN
MLHAACIH_00359 9e-248 S Erythromycin esterase
MLHAACIH_00360 1.5e-191 yceA S Belongs to the UPF0176 family
MLHAACIH_00361 1.4e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MLHAACIH_00362 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MLHAACIH_00363 5.7e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MLHAACIH_00364 4.9e-128 K UTRA
MLHAACIH_00366 3e-201 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MLHAACIH_00367 1.1e-259 mmuP E amino acid
MLHAACIH_00368 4.6e-182 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
MLHAACIH_00370 2.8e-255 agcS E Sodium alanine symporter
MLHAACIH_00371 2.9e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
MLHAACIH_00372 4.7e-228 phoQ 2.7.13.3 T Histidine kinase
MLHAACIH_00373 3.8e-168 glnL T Regulator
MLHAACIH_00374 1.9e-172 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
MLHAACIH_00375 2e-272 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MLHAACIH_00376 2.2e-254 gudP G COG0477 Permeases of the major facilitator superfamily
MLHAACIH_00377 5.7e-266 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MLHAACIH_00378 2.1e-123 ycbG K FCD
MLHAACIH_00379 1e-68 garD 4.2.1.42, 4.2.1.7 G Altronate
MLHAACIH_00380 2.9e-78 garD 4.2.1.42, 4.2.1.7 G Altronate
MLHAACIH_00381 1.1e-95 ycbJ S Macrolide 2'-phosphotransferase
MLHAACIH_00382 2.4e-53 ycbJ S Macrolide 2'-phosphotransferase
MLHAACIH_00383 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
MLHAACIH_00384 4.9e-168 eamA1 EG spore germination
MLHAACIH_00385 6.5e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLHAACIH_00386 2.7e-77 T PhoQ Sensor
MLHAACIH_00387 1.5e-77 T PhoQ Sensor
MLHAACIH_00388 4.1e-167 ycbN V ABC transporter, ATP-binding protein
MLHAACIH_00389 5.6e-113 S ABC-2 family transporter protein
MLHAACIH_00390 8.2e-53 ycbP S Protein of unknown function (DUF2512)
MLHAACIH_00391 3.4e-76 sleB 3.5.1.28 M Cell wall
MLHAACIH_00392 3.3e-135 ycbR T vWA found in TerF C terminus
MLHAACIH_00393 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
MLHAACIH_00394 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MLHAACIH_00395 2.6e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MLHAACIH_00396 1.9e-118 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MLHAACIH_00397 1.6e-202 ycbU E Selenocysteine lyase
MLHAACIH_00398 1.8e-230 lmrB EGP the major facilitator superfamily
MLHAACIH_00399 3.1e-101 yxaF K Transcriptional regulator
MLHAACIH_00400 1.9e-198 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MLHAACIH_00401 1.1e-113 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
MLHAACIH_00402 4.6e-56 S RDD family
MLHAACIH_00403 2.3e-198 yccF K DNA-templated transcriptional preinitiation complex assembly
MLHAACIH_00404 6.4e-57 2.7.13.3 T GHKL domain
MLHAACIH_00405 3.4e-56 2.7.13.3 T GHKL domain
MLHAACIH_00406 2.5e-124 lytR_2 T LytTr DNA-binding domain
MLHAACIH_00407 3.4e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
MLHAACIH_00408 4.2e-201 natB CP ABC-2 family transporter protein
MLHAACIH_00409 3.9e-173 yccK C Aldo keto reductase
MLHAACIH_00410 3.3e-176 ycdA S Domain of unknown function (DUF5105)
MLHAACIH_00411 5.3e-275 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
MLHAACIH_00412 3.1e-257 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
MLHAACIH_00413 8.1e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
MLHAACIH_00414 3.6e-173 S response regulator aspartate phosphatase
MLHAACIH_00415 2.3e-139 IQ Enoyl-(Acyl carrier protein) reductase
MLHAACIH_00416 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
MLHAACIH_00417 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
MLHAACIH_00418 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MLHAACIH_00419 6.4e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MLHAACIH_00420 2.6e-183 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLHAACIH_00421 1.9e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
MLHAACIH_00422 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
MLHAACIH_00423 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
MLHAACIH_00424 1.4e-136 terC P Protein of unknown function (DUF475)
MLHAACIH_00425 0.0 yceG S Putative component of 'biosynthetic module'
MLHAACIH_00426 9.7e-192 yceH P Belongs to the TelA family
MLHAACIH_00427 3.3e-217 naiP P Uncharacterised MFS-type transporter YbfB
MLHAACIH_00428 3.4e-203 yceJ EGP Uncharacterised MFS-type transporter YbfB
MLHAACIH_00429 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
MLHAACIH_00430 5.1e-229 proV 3.6.3.32 E glycine betaine
MLHAACIH_00431 1.3e-127 opuAB P glycine betaine
MLHAACIH_00432 1.5e-163 opuAC E glycine betaine
MLHAACIH_00433 1.2e-216 amhX S amidohydrolase
MLHAACIH_00434 1.6e-255 ycgA S Membrane
MLHAACIH_00435 2.8e-46 ycgB
MLHAACIH_00436 2.6e-269 amyE 3.2.1.1 GH13 G alpha-amylase
MLHAACIH_00437 1.8e-98 amyE 3.2.1.1 GH13 G alpha-amylase
MLHAACIH_00438 4.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MLHAACIH_00439 4.4e-289 lctP C L-lactate permease
MLHAACIH_00440 1.2e-148 yqcI S YqcI/YcgG family
MLHAACIH_00441 1.9e-101 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
MLHAACIH_00442 3.1e-37 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
MLHAACIH_00443 1.2e-93 ycgI S Domain of unknown function (DUF1989)
MLHAACIH_00444 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MLHAACIH_00445 7.5e-106 tmrB S AAA domain
MLHAACIH_00447 6.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MLHAACIH_00448 2.4e-141 yafE Q ubiE/COQ5 methyltransferase family
MLHAACIH_00449 4e-173 oxyR3 K LysR substrate binding domain
MLHAACIH_00450 2.9e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
MLHAACIH_00451 8.3e-145 ycgL S Predicted nucleotidyltransferase
MLHAACIH_00452 5.1e-170 ycgM E Proline dehydrogenase
MLHAACIH_00453 8.1e-293 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
MLHAACIH_00454 3.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLHAACIH_00455 6.2e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
MLHAACIH_00456 4.8e-146 ycgQ S membrane
MLHAACIH_00457 1.2e-139 ycgR S permeases
MLHAACIH_00458 1.6e-157 I alpha/beta hydrolase fold
MLHAACIH_00459 4e-192 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
MLHAACIH_00460 8.7e-273 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
MLHAACIH_00461 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
MLHAACIH_00462 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MLHAACIH_00463 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MLHAACIH_00464 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
MLHAACIH_00465 1.7e-221 nasA P COG2223 Nitrate nitrite transporter
MLHAACIH_00466 1.2e-171 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
MLHAACIH_00467 4.2e-101 yciB M ErfK YbiS YcfS YnhG
MLHAACIH_00468 3.6e-112 yciC S GTPases (G3E family)
MLHAACIH_00469 1.8e-98 yciC S GTPases (G3E family)
MLHAACIH_00470 1e-114 yecS P COG0765 ABC-type amino acid transport system, permease component
MLHAACIH_00471 1.5e-131 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
MLHAACIH_00473 3.7e-42 yckC S membrane
MLHAACIH_00474 7.8e-52 yckD S Protein of unknown function (DUF2680)
MLHAACIH_00475 1.2e-293 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MLHAACIH_00476 8.5e-69 nin S Competence protein J (ComJ)
MLHAACIH_00477 5.6e-69 nucA M Deoxyribonuclease NucA/NucB
MLHAACIH_00478 1.4e-176 tlpC 2.7.13.3 NT chemotaxis protein
MLHAACIH_00479 1.9e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
MLHAACIH_00480 4e-105 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
MLHAACIH_00481 6.3e-63 hxlR K transcriptional
MLHAACIH_00482 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLHAACIH_00483 3e-36 L transposase activity
MLHAACIH_00484 8.6e-208 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLHAACIH_00485 1e-182 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLHAACIH_00486 1.2e-249 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLHAACIH_00487 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLHAACIH_00488 9.7e-247 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLHAACIH_00489 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
MLHAACIH_00490 2.2e-139 srfAD Q thioesterase
MLHAACIH_00491 8.8e-226 EGP Major Facilitator Superfamily
MLHAACIH_00492 1.3e-38 S YcxB-like protein
MLHAACIH_00493 1.1e-07 S YcxB-like protein
MLHAACIH_00494 7e-84 ycxC EG EamA-like transporter family
MLHAACIH_00495 6.6e-56 ycxC EG EamA-like transporter family
MLHAACIH_00496 1.8e-248 ycxD K GntR family transcriptional regulator
MLHAACIH_00497 9.5e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
MLHAACIH_00498 9.7e-115 yczE S membrane
MLHAACIH_00499 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MLHAACIH_00500 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
MLHAACIH_00501 4.4e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
MLHAACIH_00502 1.9e-161 bsdA K LysR substrate binding domain
MLHAACIH_00503 5.4e-107 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MLHAACIH_00504 4.1e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
MLHAACIH_00505 3.4e-38 bsdD 4.1.1.61 S response to toxic substance
MLHAACIH_00506 1.6e-39 yclD
MLHAACIH_00507 4.5e-147 yclE 3.4.11.5 S Alpha beta hydrolase
MLHAACIH_00508 9.2e-262 dtpT E amino acid peptide transporter
MLHAACIH_00509 4.6e-292 yclG M Pectate lyase superfamily protein
MLHAACIH_00511 7.8e-278 gerKA EG Spore germination protein
MLHAACIH_00512 4e-226 gerKC S spore germination
MLHAACIH_00513 1.3e-194 gerKB F Spore germination protein
MLHAACIH_00514 7.3e-121 yclH P ABC transporter
MLHAACIH_00515 4.8e-202 yclI V ABC transporter (permease) YclI
MLHAACIH_00516 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLHAACIH_00517 1.3e-260 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MLHAACIH_00518 1.4e-71 S aspartate phosphatase
MLHAACIH_00522 2.8e-241 lysC 2.7.2.4 E Belongs to the aspartokinase family
MLHAACIH_00523 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLHAACIH_00524 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLHAACIH_00525 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
MLHAACIH_00526 9.4e-167 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
MLHAACIH_00527 4.1e-251 ycnB EGP Major facilitator Superfamily
MLHAACIH_00528 5.5e-153 ycnC K Transcriptional regulator
MLHAACIH_00529 2.2e-134 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
MLHAACIH_00530 1.6e-45 ycnE S Monooxygenase
MLHAACIH_00531 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
MLHAACIH_00532 4e-270 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLHAACIH_00533 1.4e-245 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MLHAACIH_00534 1.1e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MLHAACIH_00535 6.1e-149 glcU U Glucose uptake
MLHAACIH_00536 1.4e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLHAACIH_00537 6.6e-97 ycnI S protein conserved in bacteria
MLHAACIH_00538 9.7e-305 ycnJ P protein, homolog of Cu resistance protein CopC
MLHAACIH_00539 1.6e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
MLHAACIH_00540 7.3e-56
MLHAACIH_00541 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
MLHAACIH_00542 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
MLHAACIH_00543 3.4e-208 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
MLHAACIH_00544 1.1e-200 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
MLHAACIH_00545 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MLHAACIH_00546 1.2e-73 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MLHAACIH_00547 8.8e-110 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
MLHAACIH_00548 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
MLHAACIH_00550 5.2e-136 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
MLHAACIH_00551 3.6e-140 ycsF S Belongs to the UPF0271 (lamB) family
MLHAACIH_00552 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
MLHAACIH_00553 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
MLHAACIH_00554 3.6e-134 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
MLHAACIH_00555 6.9e-184 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
MLHAACIH_00556 3.9e-131 kipR K Transcriptional regulator
MLHAACIH_00557 4.9e-119 ycsK E anatomical structure formation involved in morphogenesis
MLHAACIH_00559 6.9e-32 yczJ S biosynthesis
MLHAACIH_00561 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
MLHAACIH_00562 9.2e-172 ydhF S Oxidoreductase
MLHAACIH_00563 0.0 mtlR K transcriptional regulator, MtlR
MLHAACIH_00564 1.8e-292 ydaB IQ acyl-CoA ligase
MLHAACIH_00565 2e-98 ydaC Q Methyltransferase domain
MLHAACIH_00566 7e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLHAACIH_00567 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
MLHAACIH_00568 8e-102 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MLHAACIH_00569 6.4e-75 ydaG 1.4.3.5 S general stress protein
MLHAACIH_00570 4.6e-138 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
MLHAACIH_00571 1.1e-44 ydzA EGP Major facilitator Superfamily
MLHAACIH_00572 2.5e-74 lrpC K Transcriptional regulator
MLHAACIH_00573 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MLHAACIH_00574 1.2e-205 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
MLHAACIH_00575 1.2e-89 ydaK T Diguanylate cyclase, GGDEF domain
MLHAACIH_00576 3.9e-30 ydaK T Diguanylate cyclase, GGDEF domain
MLHAACIH_00577 5e-132 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
MLHAACIH_00578 1e-176 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
MLHAACIH_00579 5.9e-233 ydaM M Glycosyl transferase family group 2
MLHAACIH_00580 1e-185 ydaN S Bacterial cellulose synthase subunit
MLHAACIH_00581 3.5e-186 ydaN S Bacterial cellulose synthase subunit
MLHAACIH_00582 0.0 ydaO E amino acid
MLHAACIH_00583 5.2e-75 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
MLHAACIH_00584 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MLHAACIH_00585 3.6e-39
MLHAACIH_00586 1.3e-224 mntH P H( )-stimulated, divalent metal cation uptake system
MLHAACIH_00588 3.7e-76 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
MLHAACIH_00589 8.4e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
MLHAACIH_00591 2.6e-58 ydbB G Cupin domain
MLHAACIH_00592 2.6e-61 ydbC S Domain of unknown function (DUF4937
MLHAACIH_00593 1.2e-138 ydbD P Catalase
MLHAACIH_00594 1.1e-197 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MLHAACIH_00595 1.5e-294 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MLHAACIH_00596 1.1e-119 dctR T COG4565 Response regulator of citrate malate metabolism
MLHAACIH_00597 3.1e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MLHAACIH_00598 2.8e-180 ydbI S AI-2E family transporter
MLHAACIH_00599 1.3e-168 ydbJ V ABC transporter, ATP-binding protein
MLHAACIH_00600 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MLHAACIH_00601 2.7e-52 ydbL
MLHAACIH_00602 3.4e-219 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
MLHAACIH_00603 1.1e-18 S Fur-regulated basic protein B
MLHAACIH_00604 2.2e-07 S Fur-regulated basic protein A
MLHAACIH_00605 4.8e-149 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MLHAACIH_00606 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MLHAACIH_00607 5.6e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MLHAACIH_00608 5.4e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MLHAACIH_00609 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MLHAACIH_00610 2.1e-82 ydbS S Bacterial PH domain
MLHAACIH_00611 8.6e-260 ydbT S Membrane
MLHAACIH_00612 6.9e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
MLHAACIH_00613 8e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MLHAACIH_00614 8.5e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
MLHAACIH_00615 4.3e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MLHAACIH_00616 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MLHAACIH_00617 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
MLHAACIH_00618 1.3e-143 rsbR T Positive regulator of sigma-B
MLHAACIH_00619 5.2e-57 rsbS T antagonist
MLHAACIH_00620 2.9e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MLHAACIH_00621 7.1e-189 rsbU 3.1.3.3 KT phosphatase
MLHAACIH_00622 3e-51 rsbV T Belongs to the anti-sigma-factor antagonist family
MLHAACIH_00623 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
MLHAACIH_00624 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLHAACIH_00625 1.4e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
MLHAACIH_00626 0.0 yhgF K COG2183 Transcriptional accessory protein
MLHAACIH_00634 1.7e-75 rimJ2 J Acetyltransferase (GNAT) domain
MLHAACIH_00636 9.3e-48 S SMI1-KNR4 cell-wall
MLHAACIH_00637 2.8e-179 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MLHAACIH_00638 1.7e-20 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MLHAACIH_00639 9.6e-11
MLHAACIH_00640 3.4e-33 K Helix-turn-helix XRE-family like proteins
MLHAACIH_00641 3.6e-39
MLHAACIH_00642 1.3e-190 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
MLHAACIH_00643 2.5e-29 cspL K Cold shock
MLHAACIH_00644 3e-78 carD K Transcription factor
MLHAACIH_00645 4.6e-35 ydzE EG spore germination
MLHAACIH_00646 3.2e-161 rhaS5 K AraC-like ligand binding domain
MLHAACIH_00647 6.3e-171 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MLHAACIH_00648 8.4e-162 ydeE K AraC family transcriptional regulator
MLHAACIH_00649 1.5e-261 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLHAACIH_00650 2.3e-154 ydeG EGP Major facilitator superfamily
MLHAACIH_00651 6.6e-102 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
MLHAACIH_00652 3e-111
MLHAACIH_00653 2.6e-31 S SNARE associated Golgi protein
MLHAACIH_00654 1.8e-14 ptsH G PTS HPr component phosphorylation site
MLHAACIH_00655 8.8e-85 K Transcriptional regulator C-terminal region
MLHAACIH_00656 7e-153 ydeK EG -transporter
MLHAACIH_00657 6e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLHAACIH_00658 1.2e-73 maoC I N-terminal half of MaoC dehydratase
MLHAACIH_00659 1.6e-105 ydeN S Serine hydrolase
MLHAACIH_00660 3e-56 K HxlR-like helix-turn-helix
MLHAACIH_00661 1.2e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
MLHAACIH_00662 2.8e-57 arsR K transcriptional
MLHAACIH_00663 2.9e-227 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MLHAACIH_00664 3.5e-73 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
MLHAACIH_00665 6.5e-142 ydfB J GNAT acetyltransferase
MLHAACIH_00666 5.9e-158 ydfC EG EamA-like transporter family
MLHAACIH_00667 7.9e-274 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLHAACIH_00668 5e-116 ydfE S Flavin reductase like domain
MLHAACIH_00669 7.8e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
MLHAACIH_00670 1e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MLHAACIH_00672 3.2e-177 ydfH 2.7.13.3 T Histidine kinase
MLHAACIH_00673 5.5e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLHAACIH_00674 0.0 ydfJ S drug exporters of the RND superfamily
MLHAACIH_00675 8.5e-117 S Protein of unknown function (DUF554)
MLHAACIH_00676 6.6e-145 K Bacterial transcription activator, effector binding domain
MLHAACIH_00678 5.6e-11 S response regulator aspartate phosphatase
MLHAACIH_00679 5.4e-13
MLHAACIH_00682 1.5e-57 L COG3666 Transposase and inactivated derivatives
MLHAACIH_00683 2.9e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MLHAACIH_00684 8.4e-108 ydfN C nitroreductase
MLHAACIH_00685 1.7e-184 ydfO E COG0346 Lactoylglutathione lyase and related lyases
MLHAACIH_00686 8.8e-63 mhqP S DoxX
MLHAACIH_00687 1.6e-55 traF CO Thioredoxin
MLHAACIH_00688 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
MLHAACIH_00689 6.3e-29
MLHAACIH_00691 7.4e-56 ydfR S Protein of unknown function (DUF421)
MLHAACIH_00692 1e-28 ydfR S Protein of unknown function (DUF421)
MLHAACIH_00693 1.5e-121 ydfS S Protein of unknown function (DUF421)
MLHAACIH_00694 1.9e-74 cotP O Belongs to the small heat shock protein (HSP20) family
MLHAACIH_00695 2.3e-37 ydgA S Spore germination protein gerPA/gerPF
MLHAACIH_00696 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
MLHAACIH_00697 2e-98 K Bacterial regulatory proteins, tetR family
MLHAACIH_00698 3.4e-50 S DoxX-like family
MLHAACIH_00699 1.7e-84 yycN 2.3.1.128 K Acetyltransferase
MLHAACIH_00700 3e-139 expZ S ABC transporter
MLHAACIH_00701 6.5e-99 expZ S ABC transporter
MLHAACIH_00702 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
MLHAACIH_00703 8.7e-90 dinB S DinB family
MLHAACIH_00704 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
MLHAACIH_00705 0.0 ydgH S drug exporters of the RND superfamily
MLHAACIH_00706 1e-113 drgA C nitroreductase
MLHAACIH_00707 7.1e-69 ydgJ K Winged helix DNA-binding domain
MLHAACIH_00708 2.2e-208 tcaB EGP Major facilitator Superfamily
MLHAACIH_00709 1.2e-121 ydhB S membrane transporter protein
MLHAACIH_00710 6.5e-122 ydhC K FCD
MLHAACIH_00711 2.2e-243 ydhD M Glycosyl hydrolase
MLHAACIH_00712 1.7e-226 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MLHAACIH_00713 1.9e-124
MLHAACIH_00714 5.2e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
MLHAACIH_00715 1.4e-65 frataxin S Domain of unknown function (DU1801)
MLHAACIH_00717 8.6e-84 K Acetyltransferase (GNAT) domain
MLHAACIH_00718 6.2e-182 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
MLHAACIH_00719 9.4e-98 ydhK M Protein of unknown function (DUF1541)
MLHAACIH_00720 4.6e-200 pbuE EGP Major facilitator Superfamily
MLHAACIH_00721 1.9e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
MLHAACIH_00722 3e-51 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
MLHAACIH_00723 2e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLHAACIH_00724 8.1e-284 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MLHAACIH_00725 1.1e-132 ydhQ K UTRA
MLHAACIH_00726 7.5e-166 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
MLHAACIH_00727 2.1e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
MLHAACIH_00728 1.2e-213 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
MLHAACIH_00729 1.8e-78 ydhU P Catalase
MLHAACIH_00730 1.1e-16 ydhU P Manganese containing catalase
MLHAACIH_00733 7.8e-08
MLHAACIH_00735 1.2e-180 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MLHAACIH_00736 1.2e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
MLHAACIH_00737 1.1e-124 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
MLHAACIH_00738 2.8e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MLHAACIH_00739 3e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MLHAACIH_00740 0.0 ydiF S ABC transporter
MLHAACIH_00741 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MLHAACIH_00742 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MLHAACIH_00743 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MLHAACIH_00744 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MLHAACIH_00745 2.9e-27 ydiK S Domain of unknown function (DUF4305)
MLHAACIH_00746 7.9e-129 ydiL S CAAX protease self-immunity
MLHAACIH_00747 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MLHAACIH_00748 8.3e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MLHAACIH_00750 2.3e-62
MLHAACIH_00752 9.3e-59
MLHAACIH_00753 2.7e-49
MLHAACIH_00754 0.0 K NB-ARC domain
MLHAACIH_00755 7.2e-200 gutB 1.1.1.14 E Dehydrogenase
MLHAACIH_00756 2.1e-252 gutA G MFS/sugar transport protein
MLHAACIH_00757 5.8e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
MLHAACIH_00758 1.3e-112 pspA KT Phage shock protein A
MLHAACIH_00759 7.5e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MLHAACIH_00760 2.5e-130 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
MLHAACIH_00761 4.1e-149 ydjI S virion core protein (lumpy skin disease virus)
MLHAACIH_00762 4.1e-144 S Ion transport 2 domain protein
MLHAACIH_00763 5.3e-27 S Ion transport 2 domain protein
MLHAACIH_00764 5.9e-258 iolT EGP Major facilitator Superfamily
MLHAACIH_00765 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
MLHAACIH_00766 4.5e-64 ydjM M Lytic transglycolase
MLHAACIH_00767 5.2e-150 ydjN U Involved in the tonB-independent uptake of proteins
MLHAACIH_00769 1.2e-34 ydjO S Cold-inducible protein YdjO
MLHAACIH_00770 5.8e-157 ydjP I Alpha/beta hydrolase family
MLHAACIH_00771 8e-177 yeaA S Protein of unknown function (DUF4003)
MLHAACIH_00772 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
MLHAACIH_00773 7.5e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
MLHAACIH_00774 3.5e-152 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MLHAACIH_00775 3e-176 yeaC S COG0714 MoxR-like ATPases
MLHAACIH_00776 1.5e-222 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
MLHAACIH_00777 0.0 yebA E COG1305 Transglutaminase-like enzymes
MLHAACIH_00778 1.9e-305 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MLHAACIH_00779 2e-89 K Belongs to the sigma-70 factor family. ECF subfamily
MLHAACIH_00780 9.8e-256 S Domain of unknown function (DUF4179)
MLHAACIH_00781 3.3e-210 pbuG S permease
MLHAACIH_00782 4.4e-117 yebC M Membrane
MLHAACIH_00784 4e-93 yebE S UPF0316 protein
MLHAACIH_00785 8e-28 yebG S NETI protein
MLHAACIH_00786 1.4e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MLHAACIH_00787 8.5e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MLHAACIH_00788 2.1e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MLHAACIH_00789 1.4e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MLHAACIH_00790 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MLHAACIH_00791 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MLHAACIH_00792 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MLHAACIH_00793 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MLHAACIH_00794 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MLHAACIH_00795 4.8e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MLHAACIH_00796 1.7e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MLHAACIH_00797 2e-233 purD 6.3.4.13 F Belongs to the GARS family
MLHAACIH_00798 1e-72 K helix_turn_helix ASNC type
MLHAACIH_00799 5.4e-226 yjeH E Amino acid permease
MLHAACIH_00800 2.7e-27 S Protein of unknown function (DUF2892)
MLHAACIH_00801 0.0 yerA 3.5.4.2 F adenine deaminase
MLHAACIH_00802 1e-187 yerB S Protein of unknown function (DUF3048) C-terminal domain
MLHAACIH_00803 4.8e-51 yerC S protein conserved in bacteria
MLHAACIH_00804 1.9e-197 yerD 1.4.7.1 E Belongs to the glutamate synthase family
MLHAACIH_00805 4.9e-32 yerD 1.4.7.1 E Belongs to the glutamate synthase family
MLHAACIH_00807 8.4e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MLHAACIH_00808 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MLHAACIH_00809 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MLHAACIH_00810 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
MLHAACIH_00811 1.2e-196 yerI S homoserine kinase type II (protein kinase fold)
MLHAACIH_00812 1.6e-123 sapB S MgtC SapB transporter
MLHAACIH_00813 7.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLHAACIH_00814 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MLHAACIH_00815 1e-273 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MLHAACIH_00816 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MLHAACIH_00817 3.1e-145 yerO K Transcriptional regulator
MLHAACIH_00818 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MLHAACIH_00819 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MLHAACIH_00820 1.9e-248 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MLHAACIH_00822 3.7e-101 S response regulator aspartate phosphatase
MLHAACIH_00824 2.6e-29 S Colicin immunity protein / pyocin immunity protein
MLHAACIH_00826 2.7e-82 S Protein of unknown function, DUF600
MLHAACIH_00827 0.0 L nucleic acid phosphodiester bond hydrolysis
MLHAACIH_00828 5.9e-96 3.4.24.40 CO amine dehydrogenase activity
MLHAACIH_00829 3.6e-58 3.4.24.40 CO amine dehydrogenase activity
MLHAACIH_00830 7.4e-211 S Tetratricopeptide repeat
MLHAACIH_00832 2.7e-126 yeeN K transcriptional regulatory protein
MLHAACIH_00834 6.7e-99 dhaR3 K Transcriptional regulator
MLHAACIH_00835 6.9e-45 cotJA S Spore coat associated protein JA (CotJA)
MLHAACIH_00836 5.6e-45 cotJB S CotJB protein
MLHAACIH_00837 2e-103 cotJC P Spore Coat
MLHAACIH_00838 6e-102 yesJ K Acetyltransferase (GNAT) family
MLHAACIH_00840 5e-100 yesL S Protein of unknown function, DUF624
MLHAACIH_00841 0.0 yesM 2.7.13.3 T Histidine kinase
MLHAACIH_00842 8.8e-201 yesN K helix_turn_helix, arabinose operon control protein
MLHAACIH_00843 3.6e-246 yesO G Bacterial extracellular solute-binding protein
MLHAACIH_00844 6.2e-171 yesP G Binding-protein-dependent transport system inner membrane component
MLHAACIH_00845 7.7e-163 yesQ P Binding-protein-dependent transport system inner membrane component
MLHAACIH_00846 3.9e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
MLHAACIH_00847 0.0 yesS K Transcriptional regulator
MLHAACIH_00848 1.1e-129 E GDSL-like Lipase/Acylhydrolase
MLHAACIH_00849 2.8e-125 yesU S Domain of unknown function (DUF1961)
MLHAACIH_00850 2.4e-110 yesV S Protein of unknown function, DUF624
MLHAACIH_00851 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
MLHAACIH_00852 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
MLHAACIH_00853 7.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
MLHAACIH_00854 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
MLHAACIH_00855 0.0 yetA
MLHAACIH_00856 1.4e-289 lplA G Bacterial extracellular solute-binding protein
MLHAACIH_00857 1.5e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
MLHAACIH_00858 1.4e-161 lplC G Binding-protein-dependent transport system inner membrane component
MLHAACIH_00859 2.3e-251 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
MLHAACIH_00860 1.7e-120 yetF S membrane
MLHAACIH_00861 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
MLHAACIH_00862 2.6e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLHAACIH_00863 1.1e-33
MLHAACIH_00864 2.7e-144 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MLHAACIH_00865 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
MLHAACIH_00866 3.6e-15 yetJ S Belongs to the BI1 family
MLHAACIH_00867 2.2e-79 yetJ S Belongs to the BI1 family
MLHAACIH_00868 2.4e-30 yetM CH FAD binding domain
MLHAACIH_00869 5.6e-134 M Membrane
MLHAACIH_00870 2.4e-195 yetN S Protein of unknown function (DUF3900)
MLHAACIH_00871 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
MLHAACIH_00872 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MLHAACIH_00873 1e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
MLHAACIH_00874 1.9e-172 yfnG 4.2.1.45 M dehydratase
MLHAACIH_00875 2.1e-179 yfnF M Nucleotide-diphospho-sugar transferase
MLHAACIH_00876 5.1e-223 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
MLHAACIH_00877 2.5e-188 yfnD M Nucleotide-diphospho-sugar transferase
MLHAACIH_00878 1.1e-204 fsr P COG0477 Permeases of the major facilitator superfamily
MLHAACIH_00879 2.8e-131 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MLHAACIH_00880 1.4e-240 yfnA E amino acid
MLHAACIH_00881 1.8e-278 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MLHAACIH_00882 4.6e-112 yfmS NT chemotaxis protein
MLHAACIH_00883 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MLHAACIH_00884 5.7e-74 yfmQ S Uncharacterised protein from bacillus cereus group
MLHAACIH_00885 1.4e-69 yfmP K transcriptional
MLHAACIH_00886 1.9e-209 yfmO EGP Major facilitator Superfamily
MLHAACIH_00888 7.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MLHAACIH_00889 2.2e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
MLHAACIH_00890 3.1e-80 yfmK 2.3.1.128 K acetyltransferase
MLHAACIH_00891 7.2e-189 yfmJ S N-terminal domain of oxidoreductase
MLHAACIH_00892 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
MLHAACIH_00893 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLHAACIH_00894 1.2e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLHAACIH_00895 3.3e-164 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
MLHAACIH_00896 2.9e-24 S Protein of unknown function (DUF3212)
MLHAACIH_00897 7.6e-58 yflT S Heat induced stress protein YflT
MLHAACIH_00898 1.1e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
MLHAACIH_00899 5.6e-235 yflS P Sodium:sulfate symporter transmembrane region
MLHAACIH_00900 2e-286 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MLHAACIH_00901 2.2e-117 citT T response regulator
MLHAACIH_00902 2.4e-178 yflP S Tripartite tricarboxylate transporter family receptor
MLHAACIH_00903 8.5e-227 citM C Citrate transporter
MLHAACIH_00904 3.9e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
MLHAACIH_00905 3.3e-216 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MLHAACIH_00906 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MLHAACIH_00907 1.1e-121 yflK S protein conserved in bacteria
MLHAACIH_00908 8.9e-18 yflJ S Protein of unknown function (DUF2639)
MLHAACIH_00909 4.1e-19 yflI
MLHAACIH_00910 5.3e-50 yflH S Protein of unknown function (DUF3243)
MLHAACIH_00911 1.2e-137 map 3.4.11.18 E Methionine aminopeptidase
MLHAACIH_00912 2e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MLHAACIH_00913 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MLHAACIH_00914 6e-67 yhdN S Domain of unknown function (DUF1992)
MLHAACIH_00915 5.9e-113 yfkQ EG Spore germination protein
MLHAACIH_00916 5.5e-256 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MLHAACIH_00917 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
MLHAACIH_00918 1.8e-133 treR K transcriptional
MLHAACIH_00919 1.5e-123 yfkO C nitroreductase
MLHAACIH_00920 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
MLHAACIH_00921 5.2e-87 yfkM 1.11.1.6, 3.5.1.124 S protease
MLHAACIH_00922 4.4e-206 ydiM EGP Major facilitator Superfamily
MLHAACIH_00923 1.3e-28 yfkK S Belongs to the UPF0435 family
MLHAACIH_00924 6.3e-79 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MLHAACIH_00925 2.4e-50 yfkI S gas vesicle protein
MLHAACIH_00926 1.3e-143 yihY S Belongs to the UPF0761 family
MLHAACIH_00928 1.7e-218 ycaD EGP COG0477 Permeases of the major facilitator superfamily
MLHAACIH_00929 6.1e-183 cax P COG0387 Ca2 H antiporter
MLHAACIH_00930 2e-146 yfkD S YfkD-like protein
MLHAACIH_00931 2.3e-148 yfkC M Mechanosensitive ion channel
MLHAACIH_00932 5.4e-222 yfkA S YfkB-like domain
MLHAACIH_00933 1.1e-26 yfjT
MLHAACIH_00934 3.8e-153 pdaA G deacetylase
MLHAACIH_00935 1.6e-109 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MLHAACIH_00936 4.4e-27 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MLHAACIH_00937 4e-181 corA P Mediates influx of magnesium ions
MLHAACIH_00938 1.3e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MLHAACIH_00939 3.4e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MLHAACIH_00940 5.1e-44 S YfzA-like protein
MLHAACIH_00941 9.3e-186 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MLHAACIH_00942 1.9e-85 yfjM S Psort location Cytoplasmic, score
MLHAACIH_00943 6.6e-29 yfjL
MLHAACIH_00944 2.6e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MLHAACIH_00945 3.8e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MLHAACIH_00946 2.4e-196 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MLHAACIH_00947 3.9e-254 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MLHAACIH_00948 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
MLHAACIH_00949 1.2e-25 sspH S Belongs to the SspH family
MLHAACIH_00950 5.2e-56 yfjF S UPF0060 membrane protein
MLHAACIH_00951 6.9e-101 yfjD S Family of unknown function (DUF5381)
MLHAACIH_00952 4.1e-144 yfjC
MLHAACIH_00953 1.8e-186 yfjB
MLHAACIH_00954 7.4e-44 yfjA S Belongs to the WXG100 family
MLHAACIH_00955 4.9e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MLHAACIH_00956 7.9e-140 glvR K Helix-turn-helix domain, rpiR family
MLHAACIH_00957 3e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MLHAACIH_00958 1.1e-306 yfiB3 V ABC transporter
MLHAACIH_00959 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
MLHAACIH_00960 6.4e-64 mhqP S DoxX
MLHAACIH_00961 2.8e-162 yfiE 1.13.11.2 S glyoxalase
MLHAACIH_00962 3e-173 K AraC-like ligand binding domain
MLHAACIH_00963 3.2e-259 iolT EGP Major facilitator Superfamily
MLHAACIH_00964 3.2e-183 G Xylose isomerase
MLHAACIH_00965 1.1e-230 S Oxidoreductase
MLHAACIH_00967 1.8e-212 yxjM T Histidine kinase
MLHAACIH_00968 6.9e-97 KT LuxR family transcriptional regulator
MLHAACIH_00969 1.5e-169 V ABC transporter, ATP-binding protein
MLHAACIH_00970 3.3e-209 V ABC-2 family transporter protein
MLHAACIH_00971 1.8e-204 V COG0842 ABC-type multidrug transport system, permease component
MLHAACIH_00972 8.9e-52 J Acetyltransferase (GNAT) domain
MLHAACIH_00973 8.3e-99 padR K transcriptional
MLHAACIH_00974 1.3e-79 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
MLHAACIH_00975 9.3e-195 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MLHAACIH_00976 1.1e-98 yfiT S Belongs to the metal hydrolase YfiT family
MLHAACIH_00977 2.6e-283 yfiU EGP Major facilitator Superfamily
MLHAACIH_00978 4.9e-79 yfiV K transcriptional
MLHAACIH_00979 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MLHAACIH_00980 6.3e-174 yfiY P ABC transporter substrate-binding protein
MLHAACIH_00981 9.9e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLHAACIH_00982 4.4e-170 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLHAACIH_00983 5.3e-164 yfhB 5.3.3.17 S PhzF family
MLHAACIH_00984 3.3e-106 yfhC C nitroreductase
MLHAACIH_00985 2.1e-25 yfhD S YfhD-like protein
MLHAACIH_00986 7.9e-171 yfhF S nucleoside-diphosphate sugar epimerase
MLHAACIH_00987 4.3e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
MLHAACIH_00988 9.7e-52 yfhH S Protein of unknown function (DUF1811)
MLHAACIH_00990 1.6e-208 yfhI EGP Major facilitator Superfamily
MLHAACIH_00991 6.2e-20 sspK S reproduction
MLHAACIH_00992 1.3e-44 yfhJ S WVELL protein
MLHAACIH_00994 1.3e-85 batE T Bacterial SH3 domain homologues
MLHAACIH_00995 1e-47 yfhL S SdpI/YhfL protein family
MLHAACIH_00996 1.1e-169 yfhM S Alpha beta hydrolase
MLHAACIH_00997 8.1e-182 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MLHAACIH_00998 0.0 yfhO S Bacterial membrane protein YfhO
MLHAACIH_00999 6.1e-185 yfhP S membrane-bound metal-dependent
MLHAACIH_01000 8.6e-211 mutY L A G-specific
MLHAACIH_01001 6.9e-36 yfhS
MLHAACIH_01002 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLHAACIH_01003 5.3e-08 sspE S Small, acid-soluble spore protein, gamma-type
MLHAACIH_01004 1.5e-37 ygaB S YgaB-like protein
MLHAACIH_01005 2.8e-104 ygaC J Belongs to the UPF0374 family
MLHAACIH_01006 1.8e-301 ygaD V ABC transporter
MLHAACIH_01007 5.6e-179 ygaE S Membrane
MLHAACIH_01008 4e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
MLHAACIH_01009 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
MLHAACIH_01010 4e-80 perR P Belongs to the Fur family
MLHAACIH_01011 9.5e-56 ygzB S UPF0295 protein
MLHAACIH_01012 6.7e-167 ygxA S Nucleotidyltransferase-like
MLHAACIH_01017 7.8e-08
MLHAACIH_01025 2e-08
MLHAACIH_01029 2.5e-141 spo0M S COG4326 Sporulation control protein
MLHAACIH_01030 1.2e-26
MLHAACIH_01031 2.3e-130 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
MLHAACIH_01032 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MLHAACIH_01033 7.6e-263 ygaK C Berberine and berberine like
MLHAACIH_01035 2.3e-289 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
MLHAACIH_01036 9.7e-138 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MLHAACIH_01037 1.6e-169 ssuA M Sulfonate ABC transporter
MLHAACIH_01038 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MLHAACIH_01039 2.6e-216 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
MLHAACIH_01041 1.7e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MLHAACIH_01042 1.7e-76 ygaO
MLHAACIH_01043 4.4e-29 K Transcriptional regulator
MLHAACIH_01045 3.9e-113 yhzB S B3/4 domain
MLHAACIH_01046 5.1e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MLHAACIH_01047 3.5e-174 yhbB S Putative amidase domain
MLHAACIH_01048 3.4e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MLHAACIH_01049 7.9e-109 yhbD K Protein of unknown function (DUF4004)
MLHAACIH_01050 3.5e-57 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
MLHAACIH_01051 9.4e-71 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
MLHAACIH_01052 0.0 prkA T Ser protein kinase
MLHAACIH_01053 2.5e-225 yhbH S Belongs to the UPF0229 family
MLHAACIH_01054 2.2e-76 yhbI K DNA-binding transcription factor activity
MLHAACIH_01055 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
MLHAACIH_01056 3.1e-271 yhcA EGP Major facilitator Superfamily
MLHAACIH_01057 5.2e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
MLHAACIH_01058 2.8e-37 yhcC
MLHAACIH_01059 4.6e-55
MLHAACIH_01060 6.6e-60 yhcF K Transcriptional regulator
MLHAACIH_01061 8.8e-122 yhcG V ABC transporter, ATP-binding protein
MLHAACIH_01062 2.6e-166 yhcH V ABC transporter, ATP-binding protein
MLHAACIH_01063 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MLHAACIH_01064 1e-30 cspB K Cold-shock protein
MLHAACIH_01065 3.1e-150 metQ M Belongs to the nlpA lipoprotein family
MLHAACIH_01066 8.4e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
MLHAACIH_01067 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MLHAACIH_01068 4.9e-41 yhcM
MLHAACIH_01069 2.1e-61 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MLHAACIH_01070 1e-158 yhcP
MLHAACIH_01071 1.6e-96 yhcQ M Spore coat protein
MLHAACIH_01072 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
MLHAACIH_01073 1.1e-101 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
MLHAACIH_01074 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MLHAACIH_01075 9.3e-68 yhcU S Family of unknown function (DUF5365)
MLHAACIH_01076 3.8e-67 yhcV S COG0517 FOG CBS domain
MLHAACIH_01077 1e-119 yhcW 5.4.2.6 S hydrolase
MLHAACIH_01078 2.3e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MLHAACIH_01079 5.4e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MLHAACIH_01080 3.4e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MLHAACIH_01081 1.4e-150 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
MLHAACIH_01082 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MLHAACIH_01083 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MLHAACIH_01084 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
MLHAACIH_01085 1.4e-212 yhcY 2.7.13.3 T Histidine kinase
MLHAACIH_01086 2e-112 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLHAACIH_01087 7.2e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
MLHAACIH_01088 3.6e-38 yhdB S YhdB-like protein
MLHAACIH_01089 1.8e-53 yhdC S Protein of unknown function (DUF3889)
MLHAACIH_01090 1e-183 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MLHAACIH_01091 1e-75 nsrR K Transcriptional regulator
MLHAACIH_01092 9.6e-238 ygxB M Conserved TM helix
MLHAACIH_01093 2e-261 ycgB S Stage V sporulation protein R
MLHAACIH_01094 1.5e-250 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
MLHAACIH_01095 7.2e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MLHAACIH_01096 3.8e-162 citR K Transcriptional regulator
MLHAACIH_01097 1.3e-204 citA 2.3.3.1 C Belongs to the citrate synthase family
MLHAACIH_01098 6e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLHAACIH_01099 7.6e-250 yhdG E amino acid
MLHAACIH_01100 1.5e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MLHAACIH_01101 2.1e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLHAACIH_01102 1e-75 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLHAACIH_01103 8.1e-45 yhdK S Sigma-M inhibitor protein
MLHAACIH_01104 6.6e-201 yhdL S Sigma factor regulator N-terminal
MLHAACIH_01105 1e-84 sigM K Belongs to the sigma-70 factor family. ECF subfamily
MLHAACIH_01106 8.3e-190 yhdN C Aldo keto reductase
MLHAACIH_01107 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MLHAACIH_01108 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MLHAACIH_01109 8e-74 cueR K transcriptional
MLHAACIH_01110 4.4e-222 yhdR 2.6.1.1 E Aminotransferase
MLHAACIH_01111 3e-210 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
MLHAACIH_01112 1.1e-43 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MLHAACIH_01113 6.2e-64 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MLHAACIH_01114 6.8e-133 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MLHAACIH_01116 5.6e-203 yhdY M Mechanosensitive ion channel
MLHAACIH_01117 2.6e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MLHAACIH_01118 3.9e-148 yheN G deacetylase
MLHAACIH_01119 1.8e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
MLHAACIH_01120 1.2e-231 nhaC C Na H antiporter
MLHAACIH_01121 3.4e-84 nhaX T Belongs to the universal stress protein A family
MLHAACIH_01122 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
MLHAACIH_01123 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
MLHAACIH_01124 6.5e-108 yheG GM NAD(P)H-binding
MLHAACIH_01125 6.3e-28 sspB S spore protein
MLHAACIH_01126 1.3e-36 yheE S Family of unknown function (DUF5342)
MLHAACIH_01127 2.8e-265 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
MLHAACIH_01128 4.8e-215 yheC HJ YheC/D like ATP-grasp
MLHAACIH_01129 4.1e-201 yheB S Belongs to the UPF0754 family
MLHAACIH_01130 9.5e-48 yheA S Belongs to the UPF0342 family
MLHAACIH_01131 1.3e-204 yhaZ L DNA alkylation repair enzyme
MLHAACIH_01132 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
MLHAACIH_01133 1.3e-292 hemZ H coproporphyrinogen III oxidase
MLHAACIH_01134 8.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
MLHAACIH_01135 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
MLHAACIH_01137 6.4e-132 yhaR 5.3.3.18 I enoyl-CoA hydratase
MLHAACIH_01138 3.2e-26 S YhzD-like protein
MLHAACIH_01139 4e-167 yhaQ S ABC transporter, ATP-binding protein
MLHAACIH_01140 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
MLHAACIH_01141 1.3e-224 yhaO L DNA repair exonuclease
MLHAACIH_01142 0.0 yhaN L AAA domain
MLHAACIH_01143 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
MLHAACIH_01144 1.6e-21 yhaL S Sporulation protein YhaL
MLHAACIH_01145 1.8e-119 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MLHAACIH_01146 8.7e-90 yhaK S Putative zincin peptidase
MLHAACIH_01147 1.3e-54 yhaI S Protein of unknown function (DUF1878)
MLHAACIH_01148 1e-113 hpr K Negative regulator of protease production and sporulation
MLHAACIH_01149 7.1e-39 yhaH S YtxH-like protein
MLHAACIH_01150 8.1e-80 trpP S Tryptophan transporter TrpP
MLHAACIH_01151 9.9e-205 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MLHAACIH_01152 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MLHAACIH_01153 4.6e-137 ecsA V transporter (ATP-binding protein)
MLHAACIH_01154 1.6e-214 ecsB U ABC transporter
MLHAACIH_01155 1.4e-114 ecsC S EcsC protein family
MLHAACIH_01156 5.7e-230 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MLHAACIH_01157 1.9e-245 yhfA C membrane
MLHAACIH_01158 1.9e-34 1.15.1.2 C Rubrerythrin
MLHAACIH_01159 9.2e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
MLHAACIH_01160 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MLHAACIH_01161 4.5e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MLHAACIH_01162 1.8e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
MLHAACIH_01163 1.2e-266 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MLHAACIH_01164 4.6e-100 yhgD K Transcriptional regulator
MLHAACIH_01165 8.6e-214 yhgE S YhgE Pip N-terminal domain protein
MLHAACIH_01166 3.1e-161 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MLHAACIH_01167 1.1e-136 yhfC S Putative membrane peptidase family (DUF2324)
MLHAACIH_01168 1e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
MLHAACIH_01169 3.7e-72 3.4.13.21 S ASCH
MLHAACIH_01170 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MLHAACIH_01171 3.4e-140 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
MLHAACIH_01172 4.9e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
MLHAACIH_01173 2.9e-111 yhfK GM NmrA-like family
MLHAACIH_01174 3.1e-300 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
MLHAACIH_01175 1.9e-65 yhfM
MLHAACIH_01176 2.5e-239 yhfN 3.4.24.84 O Peptidase M48
MLHAACIH_01177 1.2e-203 aprE 3.4.21.62 O Belongs to the peptidase S8 family
MLHAACIH_01178 6.2e-76 VY92_01935 K acetyltransferase
MLHAACIH_01179 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
MLHAACIH_01180 1.1e-154 yfmC M Periplasmic binding protein
MLHAACIH_01181 7.1e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
MLHAACIH_01182 6.5e-196 vraB 2.3.1.9 I Belongs to the thiolase family
MLHAACIH_01183 1.8e-270 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
MLHAACIH_01184 5e-91 bioY S BioY family
MLHAACIH_01185 9.2e-181 hemAT NT chemotaxis protein
MLHAACIH_01186 7.4e-97 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
MLHAACIH_01187 2.3e-184 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
MLHAACIH_01188 1.5e-155 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLHAACIH_01189 1.3e-32 yhzC S IDEAL
MLHAACIH_01190 4.2e-109 comK K Competence transcription factor
MLHAACIH_01191 2.9e-165 IQ Enoyl-(Acyl carrier protein) reductase
MLHAACIH_01192 1.1e-40 yhjA S Excalibur calcium-binding domain
MLHAACIH_01193 2.3e-265 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLHAACIH_01194 6.9e-27 yhjC S Protein of unknown function (DUF3311)
MLHAACIH_01195 6.7e-60 yhjD
MLHAACIH_01196 9.1e-110 yhjE S SNARE associated Golgi protein
MLHAACIH_01197 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
MLHAACIH_01198 1.6e-282 yhjG CH FAD binding domain
MLHAACIH_01199 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
MLHAACIH_01200 3.4e-214 glcP G Major Facilitator Superfamily
MLHAACIH_01201 4.6e-199 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
MLHAACIH_01202 9e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
MLHAACIH_01203 5.9e-79 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
MLHAACIH_01204 5.4e-116 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
MLHAACIH_01205 1.7e-187 yhjM 5.1.1.1 K Transcriptional regulator
MLHAACIH_01206 1.9e-201 abrB S membrane
MLHAACIH_01207 2.2e-213 EGP Transmembrane secretion effector
MLHAACIH_01208 0.0 S Sugar transport-related sRNA regulator N-term
MLHAACIH_01209 2.2e-78 yhjR S Rubrerythrin
MLHAACIH_01210 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
MLHAACIH_01211 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MLHAACIH_01212 9.1e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MLHAACIH_01213 0.0 sbcC L COG0419 ATPase involved in DNA repair
MLHAACIH_01214 3.1e-47 yisB V COG1403 Restriction endonuclease
MLHAACIH_01215 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
MLHAACIH_01216 3e-66 gerPE S Spore germination protein GerPE
MLHAACIH_01217 6.3e-24 gerPD S Spore germination protein
MLHAACIH_01218 5.3e-54 gerPC S Spore germination protein
MLHAACIH_01219 4e-34 gerPB S cell differentiation
MLHAACIH_01220 1.9e-33 gerPA S Spore germination protein
MLHAACIH_01221 1.5e-22 yisI S Spo0E like sporulation regulatory protein
MLHAACIH_01222 8.5e-173 cotH M Spore Coat
MLHAACIH_01223 2.1e-171 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MLHAACIH_01224 1.9e-56 yisL S UPF0344 protein
MLHAACIH_01225 0.0 wprA O Belongs to the peptidase S8 family
MLHAACIH_01226 2.8e-102 yisN S Protein of unknown function (DUF2777)
MLHAACIH_01227 0.0 asnO 6.3.5.4 E Asparagine synthase
MLHAACIH_01228 8.9e-118 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
MLHAACIH_01229 1.5e-242 yisQ V Mate efflux family protein
MLHAACIH_01230 1e-159 yisR K Transcriptional regulator
MLHAACIH_01231 5.5e-181 purR K helix_turn _helix lactose operon repressor
MLHAACIH_01232 5.2e-195 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
MLHAACIH_01233 7e-92 yisT S DinB family
MLHAACIH_01234 1.2e-106 argO S Lysine exporter protein LysE YggA
MLHAACIH_01235 7.6e-277 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLHAACIH_01236 2e-35 mcbG S Pentapeptide repeats (9 copies)
MLHAACIH_01237 4.2e-152 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MLHAACIH_01238 6e-111 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
MLHAACIH_01239 5.1e-164 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
MLHAACIH_01240 5.4e-52 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
MLHAACIH_01241 1.5e-57 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
MLHAACIH_01242 5.5e-63 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
MLHAACIH_01243 2.5e-121 comB 3.1.3.71 H Belongs to the ComB family
MLHAACIH_01244 3.5e-140 yitD 4.4.1.19 S synthase
MLHAACIH_01245 1.1e-107 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MLHAACIH_01246 1e-144 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MLHAACIH_01247 1e-154 yitG EGP Major facilitator Superfamily
MLHAACIH_01248 1.8e-156 yitH K Acetyltransferase (GNAT) domain
MLHAACIH_01249 1e-70 yjcF S Acetyltransferase (GNAT) domain
MLHAACIH_01250 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MLHAACIH_01251 8.6e-55 yajQ S Belongs to the UPF0234 family
MLHAACIH_01252 1.3e-159 cvfB S protein conserved in bacteria
MLHAACIH_01253 8.5e-94
MLHAACIH_01254 1.3e-58
MLHAACIH_01255 4.1e-87
MLHAACIH_01256 1.5e-97 S Sporulation delaying protein SdpA
MLHAACIH_01257 1.5e-58 K Transcriptional regulator PadR-like family
MLHAACIH_01258 1.6e-92
MLHAACIH_01259 1.4e-44 yitR S Domain of unknown function (DUF3784)
MLHAACIH_01260 3.2e-308 nprB 3.4.24.28 E Peptidase M4
MLHAACIH_01261 9.3e-158 yitS S protein conserved in bacteria
MLHAACIH_01262 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
MLHAACIH_01263 5e-73 ipi S Intracellular proteinase inhibitor
MLHAACIH_01264 1.2e-17 S Protein of unknown function (DUF3813)
MLHAACIH_01266 6e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
MLHAACIH_01267 1.1e-141 yjfP S COG1073 Hydrolases of the alpha beta superfamily
MLHAACIH_01268 6.2e-51 yitW S metal-sulfur cluster biosynthetic enzyme
MLHAACIH_01269 1.5e-22 pilT S Proteolipid membrane potential modulator
MLHAACIH_01270 9.2e-267 yitY C D-arabinono-1,4-lactone oxidase
MLHAACIH_01271 4.9e-88 norB G Major Facilitator Superfamily
MLHAACIH_01272 1.2e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MLHAACIH_01273 1e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MLHAACIH_01274 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
MLHAACIH_01275 2.4e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
MLHAACIH_01276 1.1e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MLHAACIH_01277 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
MLHAACIH_01278 2.8e-174 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MLHAACIH_01279 9.5e-28 yjzC S YjzC-like protein
MLHAACIH_01280 2.3e-16 yjzD S Protein of unknown function (DUF2929)
MLHAACIH_01281 6.8e-141 yjaU I carboxylic ester hydrolase activity
MLHAACIH_01282 1.7e-99 yjaV
MLHAACIH_01283 4.2e-183 med S Transcriptional activator protein med
MLHAACIH_01284 7.3e-26 comZ S ComZ
MLHAACIH_01285 2.7e-22 yjzB
MLHAACIH_01286 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MLHAACIH_01287 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MLHAACIH_01288 3.3e-149 yjaZ O Zn-dependent protease
MLHAACIH_01289 1.8e-184 appD P Belongs to the ABC transporter superfamily
MLHAACIH_01290 2.7e-185 appF E Belongs to the ABC transporter superfamily
MLHAACIH_01291 1.4e-279 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
MLHAACIH_01292 1.9e-167 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLHAACIH_01293 1.8e-154 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLHAACIH_01294 1.9e-146 yjbA S Belongs to the UPF0736 family
MLHAACIH_01295 1.7e-11 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
MLHAACIH_01296 3e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
MLHAACIH_01297 0.0 oppA E ABC transporter substrate-binding protein
MLHAACIH_01298 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLHAACIH_01299 1.8e-157 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLHAACIH_01300 3.4e-197 oppD P Belongs to the ABC transporter superfamily
MLHAACIH_01301 5.5e-172 oppF E Belongs to the ABC transporter superfamily
MLHAACIH_01302 2e-203 yjbB EGP Major Facilitator Superfamily
MLHAACIH_01303 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLHAACIH_01304 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MLHAACIH_01305 6e-112 yjbE P Integral membrane protein TerC family
MLHAACIH_01306 4.4e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MLHAACIH_01307 4e-220 yjbF S Competence protein
MLHAACIH_01308 0.0 pepF E oligoendopeptidase F
MLHAACIH_01309 1.8e-20
MLHAACIH_01311 1.2e-168 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
MLHAACIH_01312 3.7e-72 yjbI S Bacterial-like globin
MLHAACIH_01313 3.2e-98 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MLHAACIH_01314 4.1e-101 yjbK S protein conserved in bacteria
MLHAACIH_01315 7.1e-62 yjbL S Belongs to the UPF0738 family
MLHAACIH_01316 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
MLHAACIH_01317 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MLHAACIH_01318 3.4e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MLHAACIH_01319 1.5e-127 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
MLHAACIH_01320 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MLHAACIH_01321 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MLHAACIH_01322 1.1e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
MLHAACIH_01323 2.6e-216 thiO 1.4.3.19 E Glycine oxidase
MLHAACIH_01324 6.7e-30 thiS H thiamine diphosphate biosynthetic process
MLHAACIH_01325 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MLHAACIH_01326 1.9e-186 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MLHAACIH_01327 1.3e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MLHAACIH_01328 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
MLHAACIH_01329 1.4e-52 yjbX S Spore coat protein
MLHAACIH_01330 5.2e-83 cotZ S Spore coat protein
MLHAACIH_01331 3.4e-96 cotY S Spore coat protein Z
MLHAACIH_01332 6.4e-77 cotX S Spore Coat Protein X and V domain
MLHAACIH_01333 2.1e-30 cotW
MLHAACIH_01334 2.3e-55 cotV S Spore Coat Protein X and V domain
MLHAACIH_01335 4.3e-56 yjcA S Protein of unknown function (DUF1360)
MLHAACIH_01338 2.9e-38 spoVIF S Stage VI sporulation protein F
MLHAACIH_01339 0.0 yjcD 3.6.4.12 L DNA helicase
MLHAACIH_01340 1.7e-38
MLHAACIH_01341 6.6e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLHAACIH_01342 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
MLHAACIH_01343 7e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
MLHAACIH_01344 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MLHAACIH_01345 6.5e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MLHAACIH_01346 1.7e-96 rimJ 2.3.1.128 J Alanine acetyltransferase
MLHAACIH_01347 3.9e-210 yjcL S Protein of unknown function (DUF819)
MLHAACIH_01349 2.3e-18
MLHAACIH_01350 3.5e-28
MLHAACIH_01351 1e-29
MLHAACIH_01352 5e-238 M nucleic acid phosphodiester bond hydrolysis
MLHAACIH_01354 2.4e-29 KLT Protein tyrosine kinase
MLHAACIH_01355 4.3e-11 S YolD-like protein
MLHAACIH_01356 1.9e-36
MLHAACIH_01357 9e-19
MLHAACIH_01358 5.1e-18
MLHAACIH_01359 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
MLHAACIH_01360 9.2e-141 IQ Enoyl-(Acyl carrier protein) reductase
MLHAACIH_01362 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
MLHAACIH_01363 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
MLHAACIH_01364 2.5e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
MLHAACIH_01365 4.8e-51 yjdF S Protein of unknown function (DUF2992)
MLHAACIH_01366 3.6e-82 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
MLHAACIH_01367 6.8e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MLHAACIH_01368 4.2e-29 S Domain of unknown function (DUF4177)
MLHAACIH_01369 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
MLHAACIH_01370 2.8e-174 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MLHAACIH_01372 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
MLHAACIH_01373 8.8e-81 S Protein of unknown function (DUF2690)
MLHAACIH_01374 2.3e-20 yjfB S Putative motility protein
MLHAACIH_01375 1.4e-167 yjfC O Predicted Zn-dependent protease (DUF2268)
MLHAACIH_01376 3.9e-44 T PhoQ Sensor
MLHAACIH_01377 4.9e-102 yjgB S Domain of unknown function (DUF4309)
MLHAACIH_01378 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
MLHAACIH_01379 8.3e-72 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
MLHAACIH_01380 1.6e-94 yjgD S Protein of unknown function (DUF1641)
MLHAACIH_01383 3.9e-68 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
MLHAACIH_01385 8.9e-223 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
MLHAACIH_01386 4.2e-217 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MLHAACIH_01387 8.2e-30
MLHAACIH_01388 1.9e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
MLHAACIH_01389 2.8e-121 ybbM S transport system, permease component
MLHAACIH_01390 2e-135 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
MLHAACIH_01391 6.7e-176 yjlA EG Putative multidrug resistance efflux transporter
MLHAACIH_01392 1.3e-90 yjlB S Cupin domain
MLHAACIH_01393 1.2e-65 yjlC S Protein of unknown function (DUF1641)
MLHAACIH_01394 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
MLHAACIH_01395 5.1e-278 uxaC 5.3.1.12 G glucuronate isomerase
MLHAACIH_01396 3.7e-249 yjmB G symporter YjmB
MLHAACIH_01397 2.5e-189 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
MLHAACIH_01398 1.4e-187 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
MLHAACIH_01399 6.4e-212 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
MLHAACIH_01400 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MLHAACIH_01401 3.7e-227 exuT G Sugar (and other) transporter
MLHAACIH_01402 6.4e-182 exuR K transcriptional
MLHAACIH_01403 3.8e-284 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
MLHAACIH_01404 3.8e-287 uxaA 4.2.1.7, 4.4.1.24 G Altronate
MLHAACIH_01405 1.3e-129 MA20_18170 S membrane transporter protein
MLHAACIH_01406 2.3e-78 yjoA S DinB family
MLHAACIH_01407 3e-245 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
MLHAACIH_01408 2.1e-213 S response regulator aspartate phosphatase
MLHAACIH_01410 1.2e-39 S YCII-related domain
MLHAACIH_01411 1.6e-158 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
MLHAACIH_01412 1.8e-60 yjqA S Bacterial PH domain
MLHAACIH_01413 3.7e-108 yjqB S Pfam:DUF867
MLHAACIH_01414 9.8e-160 ydbD P Catalase
MLHAACIH_01415 1.6e-111 xkdA E IrrE N-terminal-like domain
MLHAACIH_01416 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
MLHAACIH_01418 7.8e-157 xkdB K sequence-specific DNA binding
MLHAACIH_01419 8.5e-109 xkdC L Bacterial dnaA protein
MLHAACIH_01422 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
MLHAACIH_01423 4.4e-86 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MLHAACIH_01424 1.4e-139 xtmA L phage terminase small subunit
MLHAACIH_01425 9.6e-255 xtmB S phage terminase, large subunit
MLHAACIH_01426 5.4e-286 yqbA S portal protein
MLHAACIH_01427 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
MLHAACIH_01428 5.8e-169 xkdG S Phage capsid family
MLHAACIH_01429 5.6e-62 yqbG S Protein of unknown function (DUF3199)
MLHAACIH_01430 8.7e-65 yqbH S Domain of unknown function (DUF3599)
MLHAACIH_01431 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
MLHAACIH_01432 9.3e-77 xkdJ
MLHAACIH_01433 2.5e-256 xkdK S Phage tail sheath C-terminal domain
MLHAACIH_01434 6.1e-76 xkdM S Phage tail tube protein
MLHAACIH_01435 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
MLHAACIH_01436 0.0 xkdO L Transglycosylase SLT domain
MLHAACIH_01437 3.4e-115 xkdP S Lysin motif
MLHAACIH_01438 2.4e-181 yqbQ 3.2.1.96 G NLP P60 protein
MLHAACIH_01439 4.7e-39 xkdR S Protein of unknown function (DUF2577)
MLHAACIH_01440 4.1e-69 xkdS S Protein of unknown function (DUF2634)
MLHAACIH_01441 1.5e-189 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MLHAACIH_01442 2.4e-101 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
MLHAACIH_01443 4.3e-40
MLHAACIH_01444 5e-138
MLHAACIH_01446 6e-11 S Phage uncharacterised protein (Phage_XkdX)
MLHAACIH_01447 4.3e-35 xhlA S Haemolysin XhlA
MLHAACIH_01448 9.3e-40 xhlB S SPP1 phage holin
MLHAACIH_01449 5e-162 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MLHAACIH_01450 6.7e-23 spoIISB S Stage II sporulation protein SB
MLHAACIH_01451 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
MLHAACIH_01452 7.6e-175 pit P phosphate transporter
MLHAACIH_01453 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
MLHAACIH_01454 1.2e-236 steT E amino acid
MLHAACIH_01455 1.8e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
MLHAACIH_01456 1.2e-205 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MLHAACIH_01457 3.8e-95 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MLHAACIH_01458 3.2e-178 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MLHAACIH_01460 3.2e-213 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MLHAACIH_01461 2.6e-133 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
MLHAACIH_01462 5.1e-153 dppA E D-aminopeptidase
MLHAACIH_01463 4.5e-155 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLHAACIH_01464 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLHAACIH_01465 3.9e-187 dppD P Belongs to the ABC transporter superfamily
MLHAACIH_01466 0.0 dppE E ABC transporter substrate-binding protein
MLHAACIH_01468 5.4e-175 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
MLHAACIH_01469 1.4e-198 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MLHAACIH_01470 2.7e-163 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MLHAACIH_01471 1.5e-186 ykfD E Belongs to the ABC transporter superfamily
MLHAACIH_01472 3.1e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
MLHAACIH_01473 1.7e-159 ykgA E Amidinotransferase
MLHAACIH_01474 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
MLHAACIH_01475 2.4e-223 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MLHAACIH_01476 2.6e-08
MLHAACIH_01477 2.3e-128 ykjA S Protein of unknown function (DUF421)
MLHAACIH_01478 5.1e-98 ykkA S Protein of unknown function (DUF664)
MLHAACIH_01479 2.5e-97 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MLHAACIH_01480 1.3e-54 ykkC P Multidrug resistance protein
MLHAACIH_01481 9.1e-50 ykkD P Multidrug resistance protein
MLHAACIH_01482 6.6e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
MLHAACIH_01483 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MLHAACIH_01484 2.4e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MLHAACIH_01486 4.8e-70 ohrA O Organic hydroperoxide resistance protein
MLHAACIH_01487 3.9e-75 ohrR K COG1846 Transcriptional regulators
MLHAACIH_01488 2.4e-71 ohrB O Organic hydroperoxide resistance protein
MLHAACIH_01489 6.2e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
MLHAACIH_01490 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MLHAACIH_01491 1.5e-175 isp O Belongs to the peptidase S8 family
MLHAACIH_01492 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MLHAACIH_01493 7.6e-135 ykoC P Cobalt transport protein
MLHAACIH_01494 5.7e-305 P ABC transporter, ATP-binding protein
MLHAACIH_01495 1.2e-98 ykoE S ABC-type cobalt transport system, permease component
MLHAACIH_01496 7.4e-109 ykoF S YKOF-related Family
MLHAACIH_01497 6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLHAACIH_01498 5.4e-240 ykoH 2.7.13.3 T Histidine kinase
MLHAACIH_01499 3.1e-111 ykoI S Peptidase propeptide and YPEB domain
MLHAACIH_01500 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
MLHAACIH_01503 2.2e-222 mgtE P Acts as a magnesium transporter
MLHAACIH_01504 1.4e-53 tnrA K transcriptional
MLHAACIH_01505 5.9e-18
MLHAACIH_01506 6.9e-26 ykoL
MLHAACIH_01507 1.3e-81 mhqR K transcriptional
MLHAACIH_01508 3.1e-217 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
MLHAACIH_01509 6.3e-97 ykoP G polysaccharide deacetylase
MLHAACIH_01510 6e-154 ykoQ S Calcineurin-like phosphoesterase superfamily domain
MLHAACIH_01511 0.0 ykoS
MLHAACIH_01512 3.1e-184 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MLHAACIH_01513 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
MLHAACIH_01514 1.4e-159 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MLHAACIH_01515 3.4e-58 ydcR 2.7.7.65 T Diguanylate cyclase
MLHAACIH_01516 8.6e-27 ydcR 2.7.7.65 T Diguanylate cyclase
MLHAACIH_01517 1.4e-23 ydcR 2.7.7.65 T Diguanylate cyclase
MLHAACIH_01518 3.9e-56 ydcR 2.7.7.65 T Diguanylate cyclase
MLHAACIH_01519 5.8e-62 ydcR 2.7.7.65 T Diguanylate cyclase
MLHAACIH_01520 1.9e-64 ydcR 2.7.7.65 T Diguanylate cyclase
MLHAACIH_01521 2.7e-109 ykoX S membrane-associated protein
MLHAACIH_01522 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MLHAACIH_01523 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLHAACIH_01524 7.2e-113 rsgI S Anti-sigma factor N-terminus
MLHAACIH_01525 1.9e-26 sspD S small acid-soluble spore protein
MLHAACIH_01526 1.9e-124 ykrK S Domain of unknown function (DUF1836)
MLHAACIH_01527 3.5e-155 htpX O Belongs to the peptidase M48B family
MLHAACIH_01528 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
MLHAACIH_01529 1.2e-10 ydfR S Protein of unknown function (DUF421)
MLHAACIH_01530 4.1e-18 ykzE
MLHAACIH_01531 1.6e-188 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
MLHAACIH_01532 0.0 kinE 2.7.13.3 T Histidine kinase
MLHAACIH_01533 7e-89 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MLHAACIH_01535 4.8e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MLHAACIH_01536 8.3e-229 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MLHAACIH_01537 1.3e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MLHAACIH_01538 3.4e-230 mtnE 2.6.1.83 E Aminotransferase
MLHAACIH_01539 2.2e-229 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
MLHAACIH_01540 3.5e-134 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MLHAACIH_01541 2.3e-113 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
MLHAACIH_01542 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MLHAACIH_01543 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
MLHAACIH_01544 6.4e-09 S Spo0E like sporulation regulatory protein
MLHAACIH_01545 1.1e-61 eag
MLHAACIH_01546 4.8e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
MLHAACIH_01547 1.3e-75 ykvE K transcriptional
MLHAACIH_01548 1.5e-122 motB N Flagellar motor protein
MLHAACIH_01549 5.1e-137 motA N flagellar motor
MLHAACIH_01550 0.0 clpE O Belongs to the ClpA ClpB family
MLHAACIH_01551 1.2e-178 ykvI S membrane
MLHAACIH_01552 6.2e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MLHAACIH_01553 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
MLHAACIH_01554 2.4e-138 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MLHAACIH_01555 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MLHAACIH_01557 7.1e-46 S Protein of unknown function (DUF1433)
MLHAACIH_01558 3e-28 S Protein of unknown function (DUF1433)
MLHAACIH_01559 1.2e-247 I Pfam Lipase (class 3)
MLHAACIH_01560 2.4e-41
MLHAACIH_01561 1.5e-89 L Belongs to the 'phage' integrase family
MLHAACIH_01562 8.3e-34 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MLHAACIH_01563 2.8e-45 ykvR S Protein of unknown function (DUF3219)
MLHAACIH_01564 6e-25 ykvS S protein conserved in bacteria
MLHAACIH_01565 2.8e-28
MLHAACIH_01566 4.8e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
MLHAACIH_01567 2.2e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLHAACIH_01568 1.6e-88 stoA CO thiol-disulfide
MLHAACIH_01569 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
MLHAACIH_01570 2.3e-09
MLHAACIH_01571 1.1e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
MLHAACIH_01572 6.4e-179 ykvZ 5.1.1.1 K Transcriptional regulator
MLHAACIH_01574 7.6e-128 glcT K antiterminator
MLHAACIH_01575 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MLHAACIH_01576 2.1e-39 ptsH G phosphocarrier protein HPr
MLHAACIH_01577 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MLHAACIH_01578 7.2e-39 splA S Transcriptional regulator
MLHAACIH_01579 1.4e-200 splB 4.1.99.14 L Spore photoproduct lyase
MLHAACIH_01580 2e-126 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLHAACIH_01581 4.4e-259 mcpC NT chemotaxis protein
MLHAACIH_01582 1.5e-158 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MLHAACIH_01583 7.5e-108 ykwD J protein with SCP PR1 domains
MLHAACIH_01584 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
MLHAACIH_01585 0.0 pilS 2.7.13.3 T Histidine kinase
MLHAACIH_01586 3.7e-221 patA 2.6.1.1 E Aminotransferase
MLHAACIH_01587 2.2e-15
MLHAACIH_01588 2.4e-167 cheV 2.7.13.3 T Chemotaxis protein CheV
MLHAACIH_01589 1.7e-84 ykyB S YkyB-like protein
MLHAACIH_01590 4.8e-238 ykuC EGP Major facilitator Superfamily
MLHAACIH_01591 1.5e-86 ykuD S protein conserved in bacteria
MLHAACIH_01592 1.6e-165 ykuE S Metallophosphoesterase
MLHAACIH_01593 6.4e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLHAACIH_01594 0.0 3.2.1.132 M Putative peptidoglycan binding domain
MLHAACIH_01596 3.3e-233 ykuI T Diguanylate phosphodiesterase
MLHAACIH_01598 3.9e-37 ykuJ S protein conserved in bacteria
MLHAACIH_01599 1.3e-93 ykuK S Ribonuclease H-like
MLHAACIH_01600 3.9e-27 ykzF S Antirepressor AbbA
MLHAACIH_01601 1.6e-76 ykuL S CBS domain
MLHAACIH_01602 3.5e-168 ccpC K Transcriptional regulator
MLHAACIH_01603 1e-84 fld C Flavodoxin domain
MLHAACIH_01604 9.7e-174 ykuO
MLHAACIH_01605 5.1e-78 fld C Flavodoxin
MLHAACIH_01606 2.4e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MLHAACIH_01607 1.2e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MLHAACIH_01608 9e-37 ykuS S Belongs to the UPF0180 family
MLHAACIH_01609 8.8e-142 ykuT M Mechanosensitive ion channel
MLHAACIH_01610 1.1e-100 ykuU O Alkyl hydroperoxide reductase
MLHAACIH_01611 1.4e-80 ykuV CO thiol-disulfide
MLHAACIH_01612 5.8e-95 rok K Repressor of ComK
MLHAACIH_01613 1.2e-145 yknT
MLHAACIH_01614 2.5e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MLHAACIH_01615 2.2e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MLHAACIH_01616 5.2e-245 moeA 2.10.1.1 H molybdopterin
MLHAACIH_01617 1.9e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
MLHAACIH_01618 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
MLHAACIH_01619 8.3e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MLHAACIH_01620 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
MLHAACIH_01621 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
MLHAACIH_01622 1e-117 yknW S Yip1 domain
MLHAACIH_01623 4.3e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MLHAACIH_01624 7.2e-124 macB V ABC transporter, ATP-binding protein
MLHAACIH_01625 8.1e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
MLHAACIH_01626 3.1e-136 fruR K Transcriptional regulator
MLHAACIH_01627 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
MLHAACIH_01628 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MLHAACIH_01629 2.4e-104 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MLHAACIH_01630 1.1e-38 ykoA
MLHAACIH_01631 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MLHAACIH_01632 2e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MLHAACIH_01633 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
MLHAACIH_01634 1.1e-12 S Uncharacterized protein YkpC
MLHAACIH_01635 7.7e-183 mreB D Rod-share determining protein MreBH
MLHAACIH_01636 1.5e-43 abrB K of stationary sporulation gene expression
MLHAACIH_01637 1.3e-240 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
MLHAACIH_01638 1.2e-154 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
MLHAACIH_01639 1.5e-115 ktrA P COG0569 K transport systems, NAD-binding component
MLHAACIH_01640 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MLHAACIH_01641 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MLHAACIH_01642 8.2e-31 ykzG S Belongs to the UPF0356 family
MLHAACIH_01643 1e-145 ykrA S hydrolases of the HAD superfamily
MLHAACIH_01644 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MLHAACIH_01646 2e-115 recN L Putative cell-wall binding lipoprotein
MLHAACIH_01647 2.2e-191 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MLHAACIH_01648 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MLHAACIH_01649 2.4e-229 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MLHAACIH_01650 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MLHAACIH_01651 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
MLHAACIH_01652 1e-276 speA 4.1.1.19 E Arginine
MLHAACIH_01653 1.6e-42 yktA S Belongs to the UPF0223 family
MLHAACIH_01654 2.1e-117 yktB S Belongs to the UPF0637 family
MLHAACIH_01655 7.2e-26 ykzI
MLHAACIH_01656 8.8e-150 suhB 3.1.3.25 G Inositol monophosphatase
MLHAACIH_01657 2.4e-60 ykzC S Acetyltransferase (GNAT) family
MLHAACIH_01658 3e-170 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MLHAACIH_01659 8.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
MLHAACIH_01660 0.0 ylaA
MLHAACIH_01661 3e-41 ylaB
MLHAACIH_01662 1.3e-88 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
MLHAACIH_01663 1.2e-11 sigC S Putative zinc-finger
MLHAACIH_01664 4.1e-38 ylaE
MLHAACIH_01665 8.2e-22 S Family of unknown function (DUF5325)
MLHAACIH_01666 0.0 typA T GTP-binding protein TypA
MLHAACIH_01667 4.2e-47 ylaH S YlaH-like protein
MLHAACIH_01668 2.5e-32 ylaI S protein conserved in bacteria
MLHAACIH_01669 4.4e-88 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MLHAACIH_01670 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
MLHAACIH_01671 1e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MLHAACIH_01672 1.4e-170 glsA 3.5.1.2 E Belongs to the glutaminase family
MLHAACIH_01673 8.7e-44 ylaN S Belongs to the UPF0358 family
MLHAACIH_01674 1.5e-209 ftsW D Belongs to the SEDS family
MLHAACIH_01675 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MLHAACIH_01676 2.2e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MLHAACIH_01677 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MLHAACIH_01678 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MLHAACIH_01679 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MLHAACIH_01680 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MLHAACIH_01681 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MLHAACIH_01682 7e-164 ctaG S cytochrome c oxidase
MLHAACIH_01683 7.7e-61 ylbA S YugN-like family
MLHAACIH_01684 2.6e-74 ylbB T COG0517 FOG CBS domain
MLHAACIH_01685 7.4e-200 ylbC S protein with SCP PR1 domains
MLHAACIH_01686 4.1e-63 ylbD S Putative coat protein
MLHAACIH_01687 6.7e-37 ylbE S YlbE-like protein
MLHAACIH_01688 1.8e-75 ylbF S Belongs to the UPF0342 family
MLHAACIH_01689 3.7e-38 ylbG S UPF0298 protein
MLHAACIH_01690 2.5e-95 rsmD 2.1.1.171 L Methyltransferase
MLHAACIH_01691 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MLHAACIH_01692 3.2e-220 ylbJ S Sporulation integral membrane protein YlbJ
MLHAACIH_01693 6.4e-137 ylbK S esterase of the alpha-beta hydrolase superfamily
MLHAACIH_01694 2.6e-186 ylbL T Belongs to the peptidase S16 family
MLHAACIH_01695 2.8e-235 ylbM S Belongs to the UPF0348 family
MLHAACIH_01697 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
MLHAACIH_01698 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MLHAACIH_01699 3.4e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MLHAACIH_01700 1.5e-88 ylbP K n-acetyltransferase
MLHAACIH_01701 2.9e-165 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MLHAACIH_01702 1.2e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MLHAACIH_01703 2.9e-78 mraZ K Belongs to the MraZ family
MLHAACIH_01704 1.6e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MLHAACIH_01705 3.7e-44 ftsL D Essential cell division protein
MLHAACIH_01706 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
MLHAACIH_01707 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
MLHAACIH_01708 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MLHAACIH_01709 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MLHAACIH_01710 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MLHAACIH_01711 5.7e-186 spoVE D Belongs to the SEDS family
MLHAACIH_01712 9.7e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MLHAACIH_01713 5.3e-167 murB 1.3.1.98 M cell wall formation
MLHAACIH_01714 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MLHAACIH_01715 5.4e-103 ylxW S protein conserved in bacteria
MLHAACIH_01716 3.1e-116 ylxX S protein conserved in bacteria
MLHAACIH_01717 1.4e-57 sbp S small basic protein
MLHAACIH_01718 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MLHAACIH_01719 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MLHAACIH_01720 0.0 bpr O COG1404 Subtilisin-like serine proteases
MLHAACIH_01721 1.6e-171 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MLHAACIH_01722 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLHAACIH_01723 6.8e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLHAACIH_01724 2.4e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MLHAACIH_01725 2.2e-251 argE 3.5.1.16 E Acetylornithine deacetylase
MLHAACIH_01726 2.4e-37 ylmC S sporulation protein
MLHAACIH_01727 1.7e-156 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
MLHAACIH_01728 6.5e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MLHAACIH_01729 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MLHAACIH_01730 1.3e-39 yggT S membrane
MLHAACIH_01731 2e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
MLHAACIH_01732 2.6e-67 divIVA D Cell division initiation protein
MLHAACIH_01733 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MLHAACIH_01734 1.3e-63 dksA T COG1734 DnaK suppressor protein
MLHAACIH_01735 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MLHAACIH_01736 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MLHAACIH_01737 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MLHAACIH_01738 2.6e-231 pyrP F Xanthine uracil
MLHAACIH_01739 1.5e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MLHAACIH_01740 3.5e-249 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MLHAACIH_01741 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MLHAACIH_01742 0.0 carB 6.3.5.5 F Belongs to the CarB family
MLHAACIH_01743 5.9e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MLHAACIH_01744 2.7e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MLHAACIH_01745 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MLHAACIH_01746 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MLHAACIH_01747 2.2e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
MLHAACIH_01748 1.4e-179 cysP P phosphate transporter
MLHAACIH_01749 2.8e-221 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
MLHAACIH_01750 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
MLHAACIH_01751 8.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
MLHAACIH_01752 3.8e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
MLHAACIH_01753 8.2e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
MLHAACIH_01754 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
MLHAACIH_01755 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
MLHAACIH_01756 2.4e-156 yloC S stress-induced protein
MLHAACIH_01757 1.5e-40 ylzA S Belongs to the UPF0296 family
MLHAACIH_01758 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MLHAACIH_01759 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MLHAACIH_01760 1.6e-222 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MLHAACIH_01761 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MLHAACIH_01762 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MLHAACIH_01763 6.5e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MLHAACIH_01764 9.3e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MLHAACIH_01765 4.1e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MLHAACIH_01766 1.6e-140 stp 3.1.3.16 T phosphatase
MLHAACIH_01767 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
MLHAACIH_01768 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MLHAACIH_01769 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MLHAACIH_01770 3.4e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
MLHAACIH_01771 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MLHAACIH_01772 5.5e-59 asp S protein conserved in bacteria
MLHAACIH_01773 1.6e-299 yloV S kinase related to dihydroxyacetone kinase
MLHAACIH_01774 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
MLHAACIH_01775 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
MLHAACIH_01776 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MLHAACIH_01777 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MLHAACIH_01778 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MLHAACIH_01779 1e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MLHAACIH_01780 6.1e-129 IQ reductase
MLHAACIH_01781 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MLHAACIH_01782 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MLHAACIH_01783 0.0 smc D Required for chromosome condensation and partitioning
MLHAACIH_01784 1.3e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MLHAACIH_01785 3.2e-125 S Phosphotransferase enzyme family
MLHAACIH_01786 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MLHAACIH_01787 3e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MLHAACIH_01788 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MLHAACIH_01789 4.5e-36 ylqC S Belongs to the UPF0109 family
MLHAACIH_01790 1.4e-60 ylqD S YlqD protein
MLHAACIH_01791 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MLHAACIH_01792 3.5e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MLHAACIH_01793 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MLHAACIH_01794 4.6e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MLHAACIH_01795 9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MLHAACIH_01796 2.7e-289 ylqG
MLHAACIH_01797 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
MLHAACIH_01798 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MLHAACIH_01799 3.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MLHAACIH_01800 8e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
MLHAACIH_01801 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MLHAACIH_01802 3.7e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MLHAACIH_01803 2.5e-169 xerC L tyrosine recombinase XerC
MLHAACIH_01804 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MLHAACIH_01805 2.2e-249 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MLHAACIH_01806 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MLHAACIH_01807 3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MLHAACIH_01808 7.6e-74 flgC N Belongs to the flagella basal body rod proteins family
MLHAACIH_01809 1.9e-31 fliE N Flagellar hook-basal body
MLHAACIH_01810 9.1e-255 fliF N The M ring may be actively involved in energy transduction
MLHAACIH_01811 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MLHAACIH_01812 9.7e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
MLHAACIH_01813 7.2e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MLHAACIH_01814 4.2e-69 fliJ N Flagellar biosynthesis chaperone
MLHAACIH_01815 3.8e-36 ylxF S MgtE intracellular N domain
MLHAACIH_01816 2.3e-220 fliK N Flagellar hook-length control protein
MLHAACIH_01817 8.7e-72 flgD N Flagellar basal body rod modification protein
MLHAACIH_01818 1.3e-137 flgG N Flagellar basal body rod
MLHAACIH_01819 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
MLHAACIH_01820 1.8e-17 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MLHAACIH_01821 1.4e-116 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MLHAACIH_01822 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MLHAACIH_01823 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
MLHAACIH_01824 6e-96 fliZ N Flagellar biosynthesis protein, FliO
MLHAACIH_01825 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
MLHAACIH_01826 6.4e-36 fliQ N Role in flagellar biosynthesis
MLHAACIH_01827 3.6e-132 fliR N Flagellar biosynthetic protein FliR
MLHAACIH_01828 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MLHAACIH_01829 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MLHAACIH_01830 1.2e-200 flhF N Flagellar biosynthesis regulator FlhF
MLHAACIH_01831 4.1e-156 flhG D Belongs to the ParA family
MLHAACIH_01832 7.5e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MLHAACIH_01833 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
MLHAACIH_01834 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
MLHAACIH_01835 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MLHAACIH_01836 4.3e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MLHAACIH_01837 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLHAACIH_01838 3.1e-76 ylxL
MLHAACIH_01839 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
MLHAACIH_01840 8.2e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MLHAACIH_01841 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MLHAACIH_01842 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MLHAACIH_01843 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MLHAACIH_01844 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
MLHAACIH_01845 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MLHAACIH_01846 7.7e-233 rasP M zinc metalloprotease
MLHAACIH_01847 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MLHAACIH_01848 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MLHAACIH_01849 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
MLHAACIH_01850 1.1e-203 nusA K Participates in both transcription termination and antitermination
MLHAACIH_01851 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
MLHAACIH_01852 3.1e-47 ylxQ J ribosomal protein
MLHAACIH_01853 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MLHAACIH_01854 5e-44 ylxP S protein conserved in bacteria
MLHAACIH_01855 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MLHAACIH_01856 7.3e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MLHAACIH_01857 6.7e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MLHAACIH_01858 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MLHAACIH_01859 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MLHAACIH_01860 2.2e-179 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
MLHAACIH_01861 4.4e-233 pepR S Belongs to the peptidase M16 family
MLHAACIH_01862 2.6e-42 ymxH S YlmC YmxH family
MLHAACIH_01863 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
MLHAACIH_01864 1.4e-107 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MLHAACIH_01865 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MLHAACIH_01866 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
MLHAACIH_01867 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MLHAACIH_01868 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MLHAACIH_01869 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
MLHAACIH_01870 4.4e-32 S YlzJ-like protein
MLHAACIH_01871 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MLHAACIH_01872 1.4e-133 ymfC K Transcriptional regulator
MLHAACIH_01873 3.8e-205 ymfD EGP Major facilitator Superfamily
MLHAACIH_01874 3.9e-232 ymfF S Peptidase M16
MLHAACIH_01875 1.4e-242 ymfH S zinc protease
MLHAACIH_01876 5e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
MLHAACIH_01877 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
MLHAACIH_01878 2.7e-143 ymfK S Protein of unknown function (DUF3388)
MLHAACIH_01879 2.1e-115 ymfM S protein conserved in bacteria
MLHAACIH_01880 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MLHAACIH_01881 8.1e-235 cinA 3.5.1.42 S Belongs to the CinA family
MLHAACIH_01882 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MLHAACIH_01883 4.4e-214 pbpX V Beta-lactamase
MLHAACIH_01884 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
MLHAACIH_01885 1.9e-152 ymdB S protein conserved in bacteria
MLHAACIH_01886 1.2e-36 spoVS S Stage V sporulation protein S
MLHAACIH_01887 7.3e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
MLHAACIH_01888 2.5e-217 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MLHAACIH_01889 1.7e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MLHAACIH_01890 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
MLHAACIH_01891 2.2e-88 cotE S Spore coat protein
MLHAACIH_01892 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MLHAACIH_01893 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MLHAACIH_01894 2.2e-68 S Regulatory protein YrvL
MLHAACIH_01895 1.1e-95 ymcC S Membrane
MLHAACIH_01896 1.2e-103 pksA K Transcriptional regulator
MLHAACIH_01897 4.4e-61 ymzB
MLHAACIH_01898 6.2e-162 ymaE S Metallo-beta-lactamase superfamily
MLHAACIH_01899 1.2e-249 aprX O Belongs to the peptidase S8 family
MLHAACIH_01900 1.9e-07 K Transcriptional regulator
MLHAACIH_01901 2.1e-126 ymaC S Replication protein
MLHAACIH_01902 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
MLHAACIH_01903 6.2e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
MLHAACIH_01904 4.9e-51 ebrA P Small Multidrug Resistance protein
MLHAACIH_01906 2.1e-46 ymaF S YmaF family
MLHAACIH_01907 3.5e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MLHAACIH_01908 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MLHAACIH_01909 8.2e-23
MLHAACIH_01910 4.5e-22 ymzA
MLHAACIH_01911 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
MLHAACIH_01912 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MLHAACIH_01913 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MLHAACIH_01914 2e-109 ymaB
MLHAACIH_01915 2.8e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MLHAACIH_01916 1.7e-176 spoVK O stage V sporulation protein K
MLHAACIH_01917 4.7e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MLHAACIH_01918 9.7e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MLHAACIH_01919 1.1e-68 glnR K transcriptional
MLHAACIH_01920 1e-259 glnA 6.3.1.2 E glutamine synthetase
MLHAACIH_01921 2.8e-54 ynaE S Domain of unknown function (DUF3885)
MLHAACIH_01923 4.2e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
MLHAACIH_01924 2.3e-254 xynT G MFS/sugar transport protein
MLHAACIH_01925 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
MLHAACIH_01926 2.3e-212 xylR GK ROK family
MLHAACIH_01927 1.4e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
MLHAACIH_01928 1.3e-290 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
MLHAACIH_01929 6.4e-111 yokF 3.1.31.1 L RNA catabolic process
MLHAACIH_01930 7.5e-253 iolT EGP Major facilitator Superfamily
MLHAACIH_01931 1e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MLHAACIH_01932 5.3e-83 yncE S Protein of unknown function (DUF2691)
MLHAACIH_01933 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
MLHAACIH_01934 5.2e-15
MLHAACIH_01937 1.9e-163 S Thymidylate synthase
MLHAACIH_01938 5.4e-32
MLHAACIH_01940 1.2e-126 S Domain of unknown function, YrpD
MLHAACIH_01943 7.9e-25 tatA U protein secretion
MLHAACIH_01944 1.3e-51
MLHAACIH_01945 2.6e-79 yndB S Activator of Hsp90 ATPase homolog 1-like protein
MLHAACIH_01948 9e-284 gerAA EG Spore germination protein
MLHAACIH_01949 1e-193 gerAB U Spore germination
MLHAACIH_01950 1.9e-182 gerLC S Spore germination protein
MLHAACIH_01951 2.9e-153 yndG S DoxX-like family
MLHAACIH_01952 5.2e-113 yndH S Domain of unknown function (DUF4166)
MLHAACIH_01953 2.3e-306 yndJ S YndJ-like protein
MLHAACIH_01955 1.5e-135 yndL S Replication protein
MLHAACIH_01956 2.9e-73 yndM S Protein of unknown function (DUF2512)
MLHAACIH_01957 1.1e-77 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
MLHAACIH_01958 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MLHAACIH_01959 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
MLHAACIH_01960 2.9e-111 yneB L resolvase
MLHAACIH_01961 1.3e-32 ynzC S UPF0291 protein
MLHAACIH_01962 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MLHAACIH_01963 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
MLHAACIH_01964 1.8e-28 yneF S UPF0154 protein
MLHAACIH_01965 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
MLHAACIH_01966 7.1e-127 ccdA O cytochrome c biogenesis protein
MLHAACIH_01967 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
MLHAACIH_01968 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
MLHAACIH_01969 1.2e-73 yneK S Protein of unknown function (DUF2621)
MLHAACIH_01970 5.9e-64 hspX O Spore coat protein
MLHAACIH_01971 3.9e-19 sspP S Belongs to the SspP family
MLHAACIH_01972 2.2e-14 sspO S Belongs to the SspO family
MLHAACIH_01973 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MLHAACIH_01974 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MLHAACIH_01976 3.1e-08 sspN S Small acid-soluble spore protein N family
MLHAACIH_01977 3.9e-35 tlp S Belongs to the Tlp family
MLHAACIH_01978 1.2e-73 yneP S Thioesterase-like superfamily
MLHAACIH_01979 1.9e-52 yneQ
MLHAACIH_01980 4.1e-49 yneR S Belongs to the HesB IscA family
MLHAACIH_01981 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MLHAACIH_01982 6.6e-69 yccU S CoA-binding protein
MLHAACIH_01983 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MLHAACIH_01984 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MLHAACIH_01985 2.3e-12
MLHAACIH_01986 8.6e-57 ynfC
MLHAACIH_01987 9e-251 agcS E Sodium alanine symporter
MLHAACIH_01988 4.2e-294 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
MLHAACIH_01990 4.2e-36
MLHAACIH_01991 3.4e-127 3.6.1.3 S Transposition protein
MLHAACIH_01992 3.1e-156 L Transposase and inactivated derivatives
MLHAACIH_01993 8.6e-39
MLHAACIH_01995 4.4e-91
MLHAACIH_01996 2.5e-49 S Protein of unknown function with PCYCGC motif
MLHAACIH_01997 2.7e-58 D peptidase
MLHAACIH_01998 2.7e-17 ywmB S TATA-box binding
MLHAACIH_01999 5.1e-197 Q Multicopper oxidase
MLHAACIH_02000 1.8e-166 T PhoQ Sensor
MLHAACIH_02001 3e-85 T Transcriptional regulatory protein, C terminal
MLHAACIH_02002 1.1e-61 ydhK M Protein of unknown function (DUF1541)
MLHAACIH_02003 1e-89 1.7.1.15, 2.1.1.131 C Nitrite reductase
MLHAACIH_02004 3.6e-98 S Membrane
MLHAACIH_02005 0.0 copA 3.6.3.54 P P-type ATPase
MLHAACIH_02006 3.4e-21 copZ P Copper resistance protein CopZ
MLHAACIH_02007 2.5e-39 S protein conserved in bacteria
MLHAACIH_02008 6e-95 lgt M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MLHAACIH_02010 2.1e-22 L Transposase
MLHAACIH_02012 2.4e-65 S HTH-like domain
MLHAACIH_02013 4.1e-31 S HTH-like domain
MLHAACIH_02014 2e-91 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
MLHAACIH_02015 1.8e-136 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
MLHAACIH_02016 1.4e-292 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
MLHAACIH_02017 1.4e-75 yngA S membrane
MLHAACIH_02018 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MLHAACIH_02019 5.5e-104 yngC S membrane-associated protein
MLHAACIH_02020 1.2e-232 nrnB S phosphohydrolase (DHH superfamily)
MLHAACIH_02021 4.5e-288 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MLHAACIH_02022 1.7e-134 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
MLHAACIH_02023 4.4e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
MLHAACIH_02024 7.3e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
MLHAACIH_02025 5.6e-250 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
MLHAACIH_02026 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MLHAACIH_02027 7e-209 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
MLHAACIH_02028 8.5e-303 yngK T Glycosyl hydrolase-like 10
MLHAACIH_02029 2.8e-64 yngL S Protein of unknown function (DUF1360)
MLHAACIH_02030 2.6e-36 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
MLHAACIH_02031 2e-161 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
MLHAACIH_02032 1e-154 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
MLHAACIH_02033 1e-260 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
MLHAACIH_02034 1.7e-290 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLHAACIH_02035 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLHAACIH_02036 1.7e-271 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
MLHAACIH_02037 6.9e-189 yoxA 5.1.3.3 G Aldose 1-epimerase
MLHAACIH_02038 2.3e-246 yoeA V MATE efflux family protein
MLHAACIH_02039 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
MLHAACIH_02041 2.2e-96 L Integrase
MLHAACIH_02042 3e-34 yoeD G Helix-turn-helix domain
MLHAACIH_02043 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
MLHAACIH_02044 8.8e-156 gltR1 K Transcriptional regulator
MLHAACIH_02045 1.8e-184 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MLHAACIH_02046 2.3e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MLHAACIH_02047 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
MLHAACIH_02048 7.8e-155 gltC K Transcriptional regulator
MLHAACIH_02049 7.8e-205 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MLHAACIH_02050 1.6e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MLHAACIH_02051 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
MLHAACIH_02052 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MLHAACIH_02053 6e-38 yoxC S Bacterial protein of unknown function (DUF948)
MLHAACIH_02054 1.5e-69 yoxB
MLHAACIH_02055 6e-94 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MLHAACIH_02056 4.5e-127 V ABC-2 family transporter protein
MLHAACIH_02057 3.7e-94 V ABC-2 family transporter protein
MLHAACIH_02058 9.7e-140 V AAA domain, putative AbiEii toxin, Type IV TA system
MLHAACIH_02059 2.5e-79 hpr K helix_turn_helix multiple antibiotic resistance protein
MLHAACIH_02060 1.2e-233 yoaB EGP Major facilitator Superfamily
MLHAACIH_02061 5.7e-280 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
MLHAACIH_02062 1.5e-183 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLHAACIH_02063 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MLHAACIH_02064 6.5e-34 yoaF
MLHAACIH_02065 5e-08 ywlA S Uncharacterised protein family (UPF0715)
MLHAACIH_02066 2.6e-13
MLHAACIH_02067 1.3e-37 S Protein of unknown function (DUF4025)
MLHAACIH_02068 1.6e-130 mcpU NT methyl-accepting chemotaxis protein
MLHAACIH_02069 6.2e-279 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
MLHAACIH_02070 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
MLHAACIH_02071 5.2e-111 yoaK S Membrane
MLHAACIH_02072 5.2e-195 pelB 4.2.2.10, 4.2.2.2 G Amb_all
MLHAACIH_02073 6.6e-130 yoqW S Belongs to the SOS response-associated peptidase family
MLHAACIH_02075 5e-164 oxdC 4.1.1.2 G Oxalate decarboxylase
MLHAACIH_02076 1.2e-52 oxdC 4.1.1.2 G Oxalate decarboxylase
MLHAACIH_02079 4.9e-36
MLHAACIH_02080 1.1e-169 yoaR V vancomycin resistance protein
MLHAACIH_02081 7.3e-75 yoaS S Protein of unknown function (DUF2975)
MLHAACIH_02082 4.4e-30 yozG K Transcriptional regulator
MLHAACIH_02083 2.4e-147 yoaT S Protein of unknown function (DUF817)
MLHAACIH_02084 8.2e-158 yoaU K LysR substrate binding domain
MLHAACIH_02085 5.3e-156 yijE EG EamA-like transporter family
MLHAACIH_02086 1.6e-76 yoaW
MLHAACIH_02087 5.9e-97 S Protein of unknown function (DUF421)
MLHAACIH_02088 2.1e-282 clsA_1 I PLD-like domain
MLHAACIH_02089 1.2e-70 S Protein of unknown function (DUF421)
MLHAACIH_02090 2.8e-07 S Protein of unknown function (DUF421)
MLHAACIH_02091 6.1e-149 yetF1 S membrane
MLHAACIH_02092 5.8e-29 S Protein of unknown function (DUF1657)
MLHAACIH_02093 2.5e-56 spoVAE S stage V sporulation protein
MLHAACIH_02094 1e-195 spoVAD I Stage V sporulation protein AD
MLHAACIH_02095 2.6e-80 spoVAC S stage V sporulation protein AC
MLHAACIH_02096 4.1e-78 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MLHAACIH_02097 6e-26 S Protein of unknown function (DUF1657)
MLHAACIH_02098 2.1e-91 cat P Catalase
MLHAACIH_02099 3.6e-21 S Protein of unknown function (DUF2642)
MLHAACIH_02100 5.3e-67 S TIGRFAM germination protein, Ger(x)C family
MLHAACIH_02101 6.3e-100 EG Spore germination protein
MLHAACIH_02102 1.5e-38 EG Spore germination protein
MLHAACIH_02103 1.2e-13 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MLHAACIH_02106 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
MLHAACIH_02107 4.9e-12
MLHAACIH_02108 1.1e-127 yydK K Transcriptional regulator
MLHAACIH_02109 3.7e-32 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
MLHAACIH_02110 3e-289 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MLHAACIH_02111 2.5e-286 ahpF O Alkyl hydroperoxide reductase
MLHAACIH_02112 3.6e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
MLHAACIH_02113 2.5e-272 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MLHAACIH_02114 5.9e-231 gntP EG COG2610 H gluconate symporter and related permeases
MLHAACIH_02115 1.2e-301 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
MLHAACIH_02116 7.3e-127 gntR K transcriptional
MLHAACIH_02117 1.2e-205 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MLHAACIH_02118 7.4e-186 yxaB GM Polysaccharide pyruvyl transferase
MLHAACIH_02119 6.1e-115 yxaC M effector of murein hydrolase
MLHAACIH_02120 1.1e-44 S LrgA family
MLHAACIH_02121 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
MLHAACIH_02122 1.2e-199 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MLHAACIH_02123 7.1e-101 yxaF K Transcriptional regulator
MLHAACIH_02124 9.6e-194 yxaG 1.13.11.24 S AraC-like ligand binding domain
MLHAACIH_02125 7.4e-225 P Protein of unknown function (DUF418)
MLHAACIH_02126 2.4e-75 yxaI S membrane protein domain
MLHAACIH_02127 7.2e-60 S Family of unknown function (DUF5391)
MLHAACIH_02128 9.9e-92 S PQQ-like domain
MLHAACIH_02129 4e-12 yxaI S membrane protein domain
MLHAACIH_02130 3.8e-246 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
MLHAACIH_02131 3.8e-207 yxbF K Bacterial regulatory proteins, tetR family
MLHAACIH_02132 2.4e-150 IQ Enoyl-(Acyl carrier protein) reductase
MLHAACIH_02134 0.0 htpG O Molecular chaperone. Has ATPase activity
MLHAACIH_02135 2.8e-244 csbC EGP Major facilitator Superfamily
MLHAACIH_02136 2.4e-47 yxcD S Protein of unknown function (DUF2653)
MLHAACIH_02138 1.9e-175 iolS C Aldo keto reductase
MLHAACIH_02139 9.5e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
MLHAACIH_02140 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MLHAACIH_02141 1.1e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MLHAACIH_02142 7.1e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MLHAACIH_02143 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MLHAACIH_02144 8.8e-175 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MLHAACIH_02145 6.2e-233 iolF EGP Major facilitator Superfamily
MLHAACIH_02146 1.8e-195 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MLHAACIH_02147 3.3e-166 iolH G Xylose isomerase-like TIM barrel
MLHAACIH_02148 2.1e-146 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
MLHAACIH_02149 4.6e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
MLHAACIH_02150 2.1e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLHAACIH_02151 1.5e-180 T PhoQ Sensor
MLHAACIH_02152 9.7e-138 yxdL V ABC transporter, ATP-binding protein
MLHAACIH_02153 0.0 yxdM V ABC transporter (permease)
MLHAACIH_02154 1.5e-58 yxeA S Protein of unknown function (DUF1093)
MLHAACIH_02155 2.3e-176 fhuD P ABC transporter
MLHAACIH_02156 8.5e-69
MLHAACIH_02157 5.6e-16 yxeD
MLHAACIH_02158 1.3e-20 yxeE
MLHAACIH_02161 1.4e-150 yidA S hydrolases of the HAD superfamily
MLHAACIH_02162 1e-187 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
MLHAACIH_02163 2.2e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLHAACIH_02164 8.9e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLHAACIH_02165 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
MLHAACIH_02166 2.9e-106 yxeN P COG0765 ABC-type amino acid transport system, permease component
MLHAACIH_02167 3.5e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
MLHAACIH_02168 2.7e-213 yxeP 3.5.1.47 E hydrolase activity
MLHAACIH_02169 1.5e-247 yxeQ S MmgE/PrpD family
MLHAACIH_02170 7.1e-198 eutH E Ethanolamine utilisation protein, EutH
MLHAACIH_02171 2e-152 yxxB S Domain of Unknown Function (DUF1206)
MLHAACIH_02172 1.8e-173 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MLHAACIH_02173 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MLHAACIH_02174 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MLHAACIH_02175 3.6e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
MLHAACIH_02176 6.3e-249 lysP E amino acid
MLHAACIH_02177 6.8e-181 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
MLHAACIH_02178 3.3e-236 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
MLHAACIH_02179 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MLHAACIH_02180 3.4e-283 hutH 4.3.1.3 E Histidine ammonia-lyase
MLHAACIH_02181 2.8e-76 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
MLHAACIH_02182 1.4e-275 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
MLHAACIH_02183 6.4e-77 L NgoFVII restriction endonuclease
MLHAACIH_02184 1.7e-96 S GTP binding
MLHAACIH_02185 4.9e-183 2.1.1.37 H C-5 cytosine-specific DNA methylase
MLHAACIH_02186 2.8e-49 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
MLHAACIH_02187 1e-20 S Domain of unknown function (DUF5082)
MLHAACIH_02188 4.7e-39 yxiC S Family of unknown function (DUF5344)
MLHAACIH_02189 1.1e-303 S nuclease activity
MLHAACIH_02190 1.1e-77 S SMI1 / KNR4 family
MLHAACIH_02191 2.9e-40
MLHAACIH_02192 5.9e-67 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MLHAACIH_02193 2.9e-173 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MLHAACIH_02194 1.1e-72 yxiE T Belongs to the universal stress protein A family
MLHAACIH_02195 1.1e-124 yxxF EG EamA-like transporter family
MLHAACIH_02196 0.0 wapA M COG3209 Rhs family protein
MLHAACIH_02197 4.1e-14 yxiJ S YxiJ-like protein
MLHAACIH_02198 6.1e-80 wapA M COG3209 Rhs family protein
MLHAACIH_02199 7e-55
MLHAACIH_02201 7.2e-139
MLHAACIH_02202 4e-93 S Protein of unknown function (DUF4240)
MLHAACIH_02203 4.9e-76
MLHAACIH_02204 8.4e-45
MLHAACIH_02205 4.3e-68 yxiG
MLHAACIH_02206 3.4e-52 yxxG
MLHAACIH_02207 1.9e-38 S Protein of unknown function (DUF2750)
MLHAACIH_02208 5.3e-16 yxiG
MLHAACIH_02209 8.3e-13 yxiG
MLHAACIH_02210 6.5e-135
MLHAACIH_02211 3.9e-84 yxiI S Protein of unknown function (DUF2716)
MLHAACIH_02212 7.7e-43 yxiJ S YxiJ-like protein
MLHAACIH_02215 6.6e-215 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
MLHAACIH_02216 8.1e-263 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
MLHAACIH_02217 2.3e-229 yxiO S COG2270 Permeases of the major facilitator superfamily
MLHAACIH_02218 1.2e-110
MLHAACIH_02219 8.8e-139 licT K transcriptional antiterminator
MLHAACIH_02220 3.3e-143 exoK GH16 M licheninase activity
MLHAACIH_02221 6.6e-224 citH C Citrate transporter
MLHAACIH_02222 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
MLHAACIH_02223 3e-47 yxiS
MLHAACIH_02224 1.2e-102 T Domain of unknown function (DUF4163)
MLHAACIH_02225 2.1e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MLHAACIH_02226 3.8e-159 rlmA 2.1.1.187 Q Methyltransferase domain
MLHAACIH_02227 1.6e-211 yxjC EG COG2610 H gluconate symporter and related permeases
MLHAACIH_02228 6.1e-25 yxjC EG COG2610 H gluconate symporter and related permeases
MLHAACIH_02229 9e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MLHAACIH_02230 2e-115 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MLHAACIH_02231 4.8e-26 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MLHAACIH_02232 1.8e-90 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MLHAACIH_02233 8.2e-218 yxjG 2.1.1.14 E Methionine synthase
MLHAACIH_02234 3.9e-220 yxjG 2.1.1.14 E Methionine synthase
MLHAACIH_02235 1.6e-85 yxjI S LURP-one-related
MLHAACIH_02238 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MLHAACIH_02239 7.1e-113 K helix_turn_helix, Lux Regulon
MLHAACIH_02240 8.3e-192 yxjM T Signal transduction histidine kinase
MLHAACIH_02241 1e-76 S Protein of unknown function (DUF1453)
MLHAACIH_02242 1e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MLHAACIH_02243 2.4e-73 yxkC S Domain of unknown function (DUF4352)
MLHAACIH_02244 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MLHAACIH_02245 6.3e-271 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MLHAACIH_02246 1.2e-163 lrp QT PucR C-terminal helix-turn-helix domain
MLHAACIH_02247 5.9e-205 msmK P Belongs to the ABC transporter superfamily
MLHAACIH_02248 1.6e-154 yxkH G Polysaccharide deacetylase
MLHAACIH_02250 3.3e-308 3.4.24.84 O Peptidase family M48
MLHAACIH_02251 6.1e-228 cimH C COG3493 Na citrate symporter
MLHAACIH_02252 3.1e-267 cydA 1.10.3.14 C oxidase, subunit
MLHAACIH_02253 1.1e-189 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
MLHAACIH_02254 1.7e-310 cydD V ATP-binding
MLHAACIH_02255 0.0 cydD V ATP-binding protein
MLHAACIH_02256 2.5e-96 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MLHAACIH_02257 1.5e-253 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
MLHAACIH_02258 4e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
MLHAACIH_02259 2.5e-39 yxlC S Family of unknown function (DUF5345)
MLHAACIH_02260 4.9e-28
MLHAACIH_02261 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
MLHAACIH_02262 2.4e-147 yxlF V ABC transporter, ATP-binding protein
MLHAACIH_02263 1.5e-98 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MLHAACIH_02264 2.5e-195 yxlH EGP Major facilitator Superfamily
MLHAACIH_02265 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
MLHAACIH_02266 1.5e-109 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
MLHAACIH_02267 1.1e-19 yxzF
MLHAACIH_02268 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
MLHAACIH_02269 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
MLHAACIH_02270 9.9e-107 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLHAACIH_02271 1.2e-123 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLHAACIH_02272 5.6e-37 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
MLHAACIH_02273 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MLHAACIH_02274 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MLHAACIH_02275 6.2e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
MLHAACIH_02276 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MLHAACIH_02277 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLHAACIH_02278 2.7e-232 dltB M membrane protein involved in D-alanine export
MLHAACIH_02279 5.7e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLHAACIH_02280 1.5e-164 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
MLHAACIH_02281 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
MLHAACIH_02282 1.5e-129 ynfM EGP Major facilitator Superfamily
MLHAACIH_02283 4.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
MLHAACIH_02284 5.3e-92 K Helix-turn-helix XRE-family like proteins
MLHAACIH_02285 2.4e-248 ywaD 3.4.11.10, 3.4.11.6 S PA domain
MLHAACIH_02286 2.2e-232 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MLHAACIH_02287 8.1e-88 ywaE K Transcriptional regulator
MLHAACIH_02288 1.9e-64 ywaF S Integral membrane protein
MLHAACIH_02289 1.2e-39 ywaF S Integral membrane protein
MLHAACIH_02290 7e-169 gspA M General stress
MLHAACIH_02291 4e-153 sacY K transcriptional antiterminator
MLHAACIH_02292 2.9e-241 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MLHAACIH_02293 2e-269 epr 3.4.21.62 O Belongs to the peptidase S8 family
MLHAACIH_02294 6.1e-241 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLHAACIH_02295 2.3e-122 ywbB S Protein of unknown function (DUF2711)
MLHAACIH_02296 4.4e-67 ywbC 4.4.1.5 E glyoxalase
MLHAACIH_02297 3.5e-219 ywbD 2.1.1.191 J Methyltransferase
MLHAACIH_02298 1.2e-26 ywbE S Uncharacterized conserved protein (DUF2196)
MLHAACIH_02299 2.2e-205 ywbF EGP Major facilitator Superfamily
MLHAACIH_02300 2.3e-111 ywbG M effector of murein hydrolase
MLHAACIH_02301 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
MLHAACIH_02302 4.3e-153 ywbI K Transcriptional regulator
MLHAACIH_02303 3.4e-141 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MLHAACIH_02304 1.2e-112 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MLHAACIH_02305 1e-249 P COG0672 High-affinity Fe2 Pb2 permease
MLHAACIH_02306 7.9e-184 ycdO P periplasmic lipoprotein involved in iron transport
MLHAACIH_02307 1.6e-222 ywbN P Dyp-type peroxidase family protein
MLHAACIH_02308 2.8e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
MLHAACIH_02309 1.5e-267 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLHAACIH_02310 9.8e-49 ywcB S Protein of unknown function, DUF485
MLHAACIH_02312 3.9e-119 ywcC K transcriptional regulator
MLHAACIH_02313 9.5e-60 gtcA S GtrA-like protein
MLHAACIH_02314 4e-228 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MLHAACIH_02315 3.3e-302 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MLHAACIH_02316 1e-35 ywzA S membrane
MLHAACIH_02317 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MLHAACIH_02318 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MLHAACIH_02319 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
MLHAACIH_02320 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
MLHAACIH_02321 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
MLHAACIH_02322 8.6e-202 rodA D Belongs to the SEDS family
MLHAACIH_02323 6.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
MLHAACIH_02324 1.1e-184 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLHAACIH_02325 0.0 vpr O Belongs to the peptidase S8 family
MLHAACIH_02328 1e-148 sacT K transcriptional antiterminator
MLHAACIH_02329 3.3e-138 focA P Formate/nitrite transporter
MLHAACIH_02330 1.9e-253 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MLHAACIH_02331 2.1e-287 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
MLHAACIH_02332 2e-28 ywdA
MLHAACIH_02333 3e-145 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MLHAACIH_02334 6.3e-57 pex K Transcriptional regulator PadR-like family
MLHAACIH_02335 7.5e-112 ywdD
MLHAACIH_02337 7.2e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
MLHAACIH_02338 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MLHAACIH_02339 5e-262 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
MLHAACIH_02340 7.7e-49 ywdI S Family of unknown function (DUF5327)
MLHAACIH_02341 1.4e-237 ywdJ F Xanthine uracil
MLHAACIH_02342 1.6e-58 ywdK S small membrane protein
MLHAACIH_02343 8.3e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MLHAACIH_02344 1.8e-144 spsA M Spore Coat
MLHAACIH_02345 1.4e-267 spsB M Capsule polysaccharide biosynthesis protein
MLHAACIH_02346 1.6e-221 spsC E Belongs to the DegT DnrJ EryC1 family
MLHAACIH_02347 3.7e-162 spsD 2.3.1.210 K Spore Coat
MLHAACIH_02348 2.1e-213 spsE 2.5.1.56 M acid synthase
MLHAACIH_02349 1.3e-128 spsF M Spore Coat
MLHAACIH_02350 2.3e-187 spsG M Spore Coat
MLHAACIH_02351 4.6e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MLHAACIH_02352 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MLHAACIH_02353 4.9e-159 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MLHAACIH_02354 1.3e-86 spsL 5.1.3.13 M Spore Coat
MLHAACIH_02355 1.2e-77
MLHAACIH_02356 6.9e-206 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
MLHAACIH_02357 1.3e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
MLHAACIH_02358 0.0 rocB E arginine degradation protein
MLHAACIH_02359 5.7e-261 lysP E amino acid
MLHAACIH_02360 4.3e-204 ywfA EGP Major facilitator Superfamily
MLHAACIH_02361 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
MLHAACIH_02362 1.2e-120 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
MLHAACIH_02363 1.5e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLHAACIH_02364 2.3e-82 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
MLHAACIH_02365 1.2e-132 IQ Enoyl-(Acyl carrier protein) reductase
MLHAACIH_02366 3.3e-146 ywfI C May function as heme-dependent peroxidase
MLHAACIH_02367 6.2e-174 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
MLHAACIH_02368 7.1e-156 cysL K Transcriptional regulator
MLHAACIH_02369 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MLHAACIH_02370 1.7e-154 ywfM EG EamA-like transporter family
MLHAACIH_02371 2.4e-107 rsfA_1
MLHAACIH_02372 3.1e-36 ywzC S Belongs to the UPF0741 family
MLHAACIH_02373 2.5e-255 ywfO S COG1078 HD superfamily phosphohydrolases
MLHAACIH_02374 2.7e-88 ywgA 2.1.1.72, 3.1.21.3
MLHAACIH_02375 6.2e-79 yffB K Transcriptional regulator
MLHAACIH_02376 1.6e-234 mmr U Major Facilitator Superfamily
MLHAACIH_02378 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MLHAACIH_02379 3.3e-71 ywhA K Transcriptional regulator
MLHAACIH_02380 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
MLHAACIH_02381 5.1e-119 ywhC S Peptidase family M50
MLHAACIH_02382 2e-94 ywhD S YwhD family
MLHAACIH_02383 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MLHAACIH_02384 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MLHAACIH_02385 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
MLHAACIH_02386 7e-27 ywhH S Aminoacyl-tRNA editing domain
MLHAACIH_02388 1.2e-78 S aspartate phosphatase
MLHAACIH_02389 3.5e-79 ywhK CO amine dehydrogenase activity
MLHAACIH_02390 4.5e-107 ywhK CO amine dehydrogenase activity
MLHAACIH_02391 2.6e-55 ywhL CO amine dehydrogenase activity
MLHAACIH_02392 6.3e-166 ywhL CO amine dehydrogenase activity
MLHAACIH_02394 6.6e-248 L Peptidase, M16
MLHAACIH_02395 1.4e-215 2.7.1.26, 2.7.7.2 L Peptidase, M16
MLHAACIH_02396 3.2e-234 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
MLHAACIH_02397 3.3e-132 cbiO V ABC transporter
MLHAACIH_02399 4.9e-270 C Fe-S oxidoreductases
MLHAACIH_02400 1e-07 S Bacteriocin subtilosin A
MLHAACIH_02401 4.7e-73 ywiB S protein conserved in bacteria
MLHAACIH_02402 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MLHAACIH_02403 1e-213 narK P COG2223 Nitrate nitrite transporter
MLHAACIH_02404 2e-129 fnr K helix_turn_helix, cAMP Regulatory protein
MLHAACIH_02405 1.1e-138 ywiC S YwiC-like protein
MLHAACIH_02406 7e-86 arfM T cyclic nucleotide binding
MLHAACIH_02407 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MLHAACIH_02408 4.3e-296 narH 1.7.5.1 C Nitrate reductase, beta
MLHAACIH_02409 1.1e-93 narJ 1.7.5.1 C nitrate reductase
MLHAACIH_02410 2.6e-123 narI 1.7.5.1 C nitrate reductase, gamma
MLHAACIH_02411 7.9e-285 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MLHAACIH_02412 0.0 ywjA V ABC transporter
MLHAACIH_02413 5.9e-94 ywjB H RibD C-terminal domain
MLHAACIH_02414 2.7e-42 ywjC
MLHAACIH_02415 2.5e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
MLHAACIH_02416 3.2e-220 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MLHAACIH_02417 0.0 fadF C COG0247 Fe-S oxidoreductase
MLHAACIH_02418 1.4e-209 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
MLHAACIH_02419 1.4e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MLHAACIH_02420 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MLHAACIH_02421 2.5e-11 tnpIS3 L Transposase
MLHAACIH_02422 1.3e-90 ywjG S Domain of unknown function (DUF2529)
MLHAACIH_02423 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
MLHAACIH_02424 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
MLHAACIH_02425 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MLHAACIH_02426 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MLHAACIH_02427 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
MLHAACIH_02428 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MLHAACIH_02429 1.1e-32 rpmE J Binds the 23S rRNA
MLHAACIH_02430 1.6e-103 tdk 2.7.1.21 F thymidine kinase
MLHAACIH_02431 0.0 sfcA 1.1.1.38 C malic enzyme
MLHAACIH_02432 8.6e-160 ywkB S Membrane transport protein
MLHAACIH_02433 5.1e-88 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
MLHAACIH_02434 2.1e-64 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLHAACIH_02435 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MLHAACIH_02436 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MLHAACIH_02438 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
MLHAACIH_02439 6.1e-112 spoIIR S stage II sporulation protein R
MLHAACIH_02440 2.1e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
MLHAACIH_02441 2.2e-193 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MLHAACIH_02442 1.1e-90 mntP P Probably functions as a manganese efflux pump
MLHAACIH_02443 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MLHAACIH_02444 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
MLHAACIH_02445 1.6e-94 ywlG S Belongs to the UPF0340 family
MLHAACIH_02446 6e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MLHAACIH_02447 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MLHAACIH_02448 2.5e-62 atpI S ATP synthase
MLHAACIH_02449 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
MLHAACIH_02450 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MLHAACIH_02451 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MLHAACIH_02452 2e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MLHAACIH_02453 2.9e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MLHAACIH_02454 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MLHAACIH_02455 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MLHAACIH_02456 8.5e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MLHAACIH_02457 4.8e-87 ywmA
MLHAACIH_02458 1.3e-32 ywzB S membrane
MLHAACIH_02459 3.4e-132 ywmB S TATA-box binding
MLHAACIH_02460 3.6e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MLHAACIH_02461 9.8e-178 spoIID D Stage II sporulation protein D
MLHAACIH_02462 3.3e-121 ywmC S protein containing a von Willebrand factor type A (vWA) domain
MLHAACIH_02463 2.7e-120 ywmD S protein containing a von Willebrand factor type A (vWA) domain
MLHAACIH_02465 2.9e-145 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MLHAACIH_02466 2e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MLHAACIH_02467 7.9e-104 S response regulator aspartate phosphatase
MLHAACIH_02468 5.1e-84 ywmF S Peptidase M50
MLHAACIH_02469 3.6e-09 csbD K CsbD-like
MLHAACIH_02470 8.8e-221 urtA E Receptor family ligand binding region
MLHAACIH_02471 4.6e-147 urtB E Belongs to the binding-protein-dependent transport system permease family
MLHAACIH_02472 3.6e-183 urtC E Belongs to the binding-protein-dependent transport system permease family
MLHAACIH_02473 1.4e-120 urtD S ATPases associated with a variety of cellular activities
MLHAACIH_02474 4.4e-113 urtE E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
MLHAACIH_02475 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
MLHAACIH_02476 1.6e-61 ureB 3.5.1.5 E Belongs to the urease beta subunit family
MLHAACIH_02477 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MLHAACIH_02478 1.7e-64 ywnA K Transcriptional regulator
MLHAACIH_02479 4.2e-110 ywnB S NAD(P)H-binding
MLHAACIH_02480 1.7e-58 ywnC S Family of unknown function (DUF5362)
MLHAACIH_02481 5.9e-143 mta K transcriptional
MLHAACIH_02482 2.7e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MLHAACIH_02483 3.2e-69 ywnF S Family of unknown function (DUF5392)
MLHAACIH_02484 1.4e-07 ywnC S Family of unknown function (DUF5362)
MLHAACIH_02485 2e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
MLHAACIH_02486 2e-115 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
MLHAACIH_02487 2.3e-72 ywnJ S VanZ like family
MLHAACIH_02488 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
MLHAACIH_02489 1.6e-58 nrgB K Belongs to the P(II) protein family
MLHAACIH_02490 2.5e-225 amt P Ammonium transporter
MLHAACIH_02491 2.2e-76
MLHAACIH_02492 1.2e-103 phzA Q Isochorismatase family
MLHAACIH_02493 1.6e-239 ywoD EGP Major facilitator superfamily
MLHAACIH_02494 9.8e-280 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
MLHAACIH_02495 1.5e-224 ywoF P Right handed beta helix region
MLHAACIH_02496 4.6e-211 ywoG EGP Major facilitator Superfamily
MLHAACIH_02497 2.1e-70 ywoH K COG1846 Transcriptional regulators
MLHAACIH_02498 3e-44 spoIIID K Stage III sporulation protein D
MLHAACIH_02499 3.5e-180 mbl D Rod shape-determining protein
MLHAACIH_02500 6.9e-126 flhO N flagellar basal body
MLHAACIH_02501 2.6e-141 flhP N flagellar basal body
MLHAACIH_02502 2.3e-198 S aspartate phosphatase
MLHAACIH_02503 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MLHAACIH_02504 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MLHAACIH_02505 1.2e-152 ywpD T Histidine kinase
MLHAACIH_02506 2.6e-49 srtA 3.4.22.70 M Sortase family
MLHAACIH_02507 6.9e-66 ywpF S YwpF-like protein
MLHAACIH_02508 1.9e-65 ywpG
MLHAACIH_02509 9.8e-58 ssbB L Single-stranded DNA-binding protein
MLHAACIH_02510 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
MLHAACIH_02511 1.3e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
MLHAACIH_02512 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
MLHAACIH_02513 7.8e-307 ywqB S SWIM zinc finger
MLHAACIH_02514 1.2e-17
MLHAACIH_02515 5.9e-116 ywqC M biosynthesis protein
MLHAACIH_02516 2.2e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
MLHAACIH_02517 3e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
MLHAACIH_02518 1.7e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MLHAACIH_02519 5.4e-152 ywqG S Domain of unknown function (DUF1963)
MLHAACIH_02520 1.3e-19 S Domain of unknown function (DUF5082)
MLHAACIH_02521 1.2e-37 ywqI S Family of unknown function (DUF5344)
MLHAACIH_02522 3.3e-213 ywqJ L nucleic acid phosphodiester bond hydrolysis
MLHAACIH_02523 7.9e-43
MLHAACIH_02524 5.2e-17
MLHAACIH_02525 1.6e-81 ywqJ S Pre-toxin TG
MLHAACIH_02526 3.9e-25
MLHAACIH_02527 3e-117 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
MLHAACIH_02528 1.4e-161 K Transcriptional regulator
MLHAACIH_02529 1.1e-100 ywqN S NAD(P)H-dependent
MLHAACIH_02531 2.2e-88 ywrA P COG2059 Chromate transport protein ChrA
MLHAACIH_02532 1.2e-103 ywrB P Chromate transporter
MLHAACIH_02533 8e-82 ywrC K Transcriptional regulator
MLHAACIH_02534 1.1e-300 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
MLHAACIH_02535 2.7e-52 S Domain of unknown function (DUF4181)
MLHAACIH_02536 9.9e-109 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MLHAACIH_02537 1.1e-12
MLHAACIH_02538 2.4e-206 cotH M Spore Coat
MLHAACIH_02539 1.4e-23 cotB
MLHAACIH_02540 8.8e-77 cotB
MLHAACIH_02541 1.4e-124 ywrJ
MLHAACIH_02542 2.4e-179 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MLHAACIH_02543 1.1e-169 alsR K LysR substrate binding domain
MLHAACIH_02544 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MLHAACIH_02545 1.4e-144 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
MLHAACIH_02546 6.3e-96 ywrO S NADPH-quinone reductase (modulator of drug activity B)
MLHAACIH_02547 8e-48 ywsA S Protein of unknown function (DUF3892)
MLHAACIH_02548 1.2e-91 batE T Sh3 type 3 domain protein
MLHAACIH_02549 1.2e-158 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
MLHAACIH_02550 9.3e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
MLHAACIH_02551 4e-273 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MLHAACIH_02552 1.4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MLHAACIH_02553 2.5e-161 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MLHAACIH_02554 5.5e-178 rbsR K transcriptional
MLHAACIH_02555 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
MLHAACIH_02556 8.6e-70 pgsC S biosynthesis protein
MLHAACIH_02557 9.1e-217 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
MLHAACIH_02558 3.6e-21 ywtC
MLHAACIH_02559 4.9e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MLHAACIH_02560 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
MLHAACIH_02561 2.4e-170 ywtF K Transcriptional regulator
MLHAACIH_02562 1.7e-246 ywtG EGP Major facilitator Superfamily
MLHAACIH_02563 1.4e-206 gerAC S Spore germination protein
MLHAACIH_02564 1.3e-191 gerBB E Spore germination protein
MLHAACIH_02565 5.3e-262 gerBA EG Spore germination protein
MLHAACIH_02566 4.3e-188 pmi 5.3.1.8 G mannose-6-phosphate isomerase
MLHAACIH_02567 6.8e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MLHAACIH_02568 3.5e-260
MLHAACIH_02569 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MLHAACIH_02570 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MLHAACIH_02571 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
MLHAACIH_02572 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
MLHAACIH_02573 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MLHAACIH_02574 1.1e-150 tagG GM Transport permease protein
MLHAACIH_02575 2.2e-277 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MLHAACIH_02576 1.6e-100 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MLHAACIH_02578 1.4e-256 ggaA M Glycosyltransferase like family 2
MLHAACIH_02579 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MLHAACIH_02580 2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MLHAACIH_02581 1e-215 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MLHAACIH_02582 4e-162 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MLHAACIH_02583 6e-38
MLHAACIH_02584 0.0 lytB 3.5.1.28 D Stage II sporulation protein
MLHAACIH_02585 5.6e-267 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MLHAACIH_02586 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MLHAACIH_02587 7.4e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLHAACIH_02588 1.7e-218 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
MLHAACIH_02589 7.6e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MLHAACIH_02590 5.4e-262 tuaE M Teichuronic acid biosynthesis protein
MLHAACIH_02591 3.9e-114 tuaF M protein involved in exopolysaccharide biosynthesis
MLHAACIH_02592 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
MLHAACIH_02593 1.3e-234 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
MLHAACIH_02594 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
MLHAACIH_02595 6e-163 yvhJ K Transcriptional regulator
MLHAACIH_02596 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
MLHAACIH_02597 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MLHAACIH_02598 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLHAACIH_02599 2.1e-154 degV S protein conserved in bacteria
MLHAACIH_02600 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MLHAACIH_02601 5.7e-46 comFB S Late competence development protein ComFB
MLHAACIH_02602 2.7e-129 comFC S Phosphoribosyl transferase domain
MLHAACIH_02603 7e-74 yvyF S flagellar protein
MLHAACIH_02604 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
MLHAACIH_02605 2.4e-78 flgN NOU FlgN protein
MLHAACIH_02606 4.6e-264 flgK N flagellar hook-associated protein
MLHAACIH_02607 7.8e-155 flgL N Belongs to the bacterial flagellin family
MLHAACIH_02608 5.7e-50 yviE
MLHAACIH_02609 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MLHAACIH_02610 1.7e-29 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MLHAACIH_02611 1.2e-114 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MLHAACIH_02612 1.2e-52 flaG N flagellar protein FlaG
MLHAACIH_02613 7.7e-248 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MLHAACIH_02614 1.9e-68 fliS N flagellar protein FliS
MLHAACIH_02615 1.9e-08 fliT S bacterial-type flagellum organization
MLHAACIH_02616 4.6e-51
MLHAACIH_02617 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MLHAACIH_02618 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MLHAACIH_02619 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MLHAACIH_02620 7.1e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
MLHAACIH_02621 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
MLHAACIH_02622 1.6e-123 ftsE D cell division ATP-binding protein FtsE
MLHAACIH_02623 2.1e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MLHAACIH_02624 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
MLHAACIH_02625 5.3e-56 swrA S Swarming motility protein
MLHAACIH_02626 1.9e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MLHAACIH_02627 3.3e-226 yvkA EGP Major facilitator Superfamily
MLHAACIH_02628 1e-99 yvkB K Transcriptional regulator
MLHAACIH_02629 0.0 yvkC 2.7.9.2 GT Phosphotransferase
MLHAACIH_02630 1.2e-30 csbA S protein conserved in bacteria
MLHAACIH_02631 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MLHAACIH_02632 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MLHAACIH_02633 1.2e-114 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MLHAACIH_02634 5.7e-33 yvkN
MLHAACIH_02635 8e-49 yvlA
MLHAACIH_02636 2.4e-166 yvlB S Putative adhesin
MLHAACIH_02637 2.6e-26 pspB KT PspC domain
MLHAACIH_02638 1.2e-50 yvlD S Membrane
MLHAACIH_02639 2.7e-203 yvmA EGP Major facilitator Superfamily
MLHAACIH_02640 7.4e-86 yvmB K helix_turn_helix multiple antibiotic resistance protein
MLHAACIH_02641 1.8e-136 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
MLHAACIH_02642 3.8e-229 cypX 1.14.15.13 C Cytochrome P450
MLHAACIH_02643 4.2e-83 adcR K helix_turn_helix multiple antibiotic resistance protein
MLHAACIH_02644 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
MLHAACIH_02645 3.6e-134 yvoA K transcriptional
MLHAACIH_02646 1.2e-129 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MLHAACIH_02647 8.3e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MLHAACIH_02648 2.9e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MLHAACIH_02649 1.4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MLHAACIH_02650 1.1e-162 yvoD P COG0370 Fe2 transport system protein B
MLHAACIH_02651 3.2e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MLHAACIH_02652 1.6e-80 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
MLHAACIH_02653 1.5e-118 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
MLHAACIH_02654 3.8e-139 yvpB NU protein conserved in bacteria
MLHAACIH_02655 2.4e-220 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MLHAACIH_02656 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MLHAACIH_02657 3.8e-227 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MLHAACIH_02658 1.8e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
MLHAACIH_02659 1.1e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MLHAACIH_02660 2.5e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MLHAACIH_02661 1.4e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MLHAACIH_02662 8.8e-113 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
MLHAACIH_02663 4.7e-118
MLHAACIH_02664 0.0
MLHAACIH_02666 0.0 msbA2 3.6.3.44 V ABC transporter
MLHAACIH_02667 1e-276 S COG0457 FOG TPR repeat
MLHAACIH_02668 1.4e-97 usp CBM50 M protein conserved in bacteria
MLHAACIH_02669 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MLHAACIH_02670 3.9e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MLHAACIH_02671 5.7e-166 rapZ S Displays ATPase and GTPase activities
MLHAACIH_02672 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MLHAACIH_02673 4.1e-170 whiA K May be required for sporulation
MLHAACIH_02674 1.6e-36 crh G Phosphocarrier protein Chr
MLHAACIH_02675 2.2e-142 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
MLHAACIH_02676 2.8e-31
MLHAACIH_02677 4.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLHAACIH_02678 7.5e-197 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
MLHAACIH_02679 5.6e-141 yvcR V ABC transporter, ATP-binding protein
MLHAACIH_02680 4.6e-23 yxdM V ABC transporter (permease)
MLHAACIH_02681 1.6e-302 yxdM V ABC transporter (permease)
MLHAACIH_02682 8.7e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLHAACIH_02683 7.4e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
MLHAACIH_02684 3.1e-287 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
MLHAACIH_02685 1.5e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
MLHAACIH_02686 4.7e-105 yvdD 3.2.2.10 S Belongs to the LOG family
MLHAACIH_02687 3.3e-172 yvdE K Transcriptional regulator
MLHAACIH_02688 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
MLHAACIH_02689 2.4e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
MLHAACIH_02690 4.5e-244 malC P COG1175 ABC-type sugar transport systems, permease components
MLHAACIH_02691 9.5e-147 malD P transport
MLHAACIH_02692 5e-154 malA S Protein of unknown function (DUF1189)
MLHAACIH_02693 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
MLHAACIH_02694 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
MLHAACIH_02695 1.3e-114 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
MLHAACIH_02696 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MLHAACIH_02698 1e-75 L Phage integrase family
MLHAACIH_02699 7.4e-103 S Helix-turn-helix domain
MLHAACIH_02700 1.2e-22
MLHAACIH_02702 5.8e-103 L Phage integrase family
MLHAACIH_02703 9.7e-12 K Cro/C1-type HTH DNA-binding domain
MLHAACIH_02705 5.7e-11 K sequence-specific DNA binding
MLHAACIH_02706 8.3e-56
MLHAACIH_02712 5.8e-09 K Helix-turn-helix XRE-family like proteins
MLHAACIH_02713 1.2e-18
MLHAACIH_02715 1e-42
MLHAACIH_02716 3.3e-08 K sequence-specific DNA binding
MLHAACIH_02717 1.2e-31 L HNH endonuclease
MLHAACIH_02718 2e-44 L Phage terminase, small subunit
MLHAACIH_02719 0.0 S Terminase
MLHAACIH_02720 2.7e-225 S Phage portal protein
MLHAACIH_02721 2.8e-110 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
MLHAACIH_02722 3.8e-162 S Phage capsid family
MLHAACIH_02723 5.8e-27 N domain, Protein
MLHAACIH_02724 3.5e-25 S Phage gp6-like head-tail connector protein
MLHAACIH_02725 2.6e-34 S Phage head-tail joining protein
MLHAACIH_02726 9.9e-07 S Bacteriophage HK97-gp10, putative tail-component
MLHAACIH_02727 8.5e-25
MLHAACIH_02728 5.5e-72 N phage major tail protein, phi13 family
MLHAACIH_02729 2.7e-31
MLHAACIH_02730 7.2e-123 S Phage-related minor tail protein
MLHAACIH_02731 1.7e-108 S Phage tail protein
MLHAACIH_02732 6.3e-189 L Prophage endopeptidase tail
MLHAACIH_02733 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
MLHAACIH_02734 1.2e-95
MLHAACIH_02735 1.3e-15
MLHAACIH_02737 1.1e-29 S Haemolysin XhlA
MLHAACIH_02738 8.4e-152 xlyB 3.5.1.28 CBM50 MT N-acetylmuramoyl-L-alanine amidase
MLHAACIH_02739 4.8e-33 S Bacteriophage A118-like holin, Hol118
MLHAACIH_02740 6.3e-62
MLHAACIH_02741 1.3e-72 yvdQ S Protein of unknown function (DUF3231)
MLHAACIH_02742 2.1e-49 sugE P Small Multidrug Resistance protein
MLHAACIH_02743 1.6e-49 ykkC P Small Multidrug Resistance protein
MLHAACIH_02744 2.2e-105 yvdT K Transcriptional regulator
MLHAACIH_02745 3.3e-294 yveA E amino acid
MLHAACIH_02746 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
MLHAACIH_02747 3.5e-274 sacB 2.4.1.10 GH68 M levansucrase activity
MLHAACIH_02748 5.9e-263 pbpE V Beta-lactamase
MLHAACIH_02749 8.4e-125 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
MLHAACIH_02750 4.2e-72 MA20_18690 S Protein of unknown function (DUF3237)
MLHAACIH_02751 1.7e-92 padC Q Phenolic acid decarboxylase
MLHAACIH_02753 5.3e-278 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
MLHAACIH_02754 3.1e-75 slr K transcriptional
MLHAACIH_02755 2.2e-120 ywqC M biosynthesis protein
MLHAACIH_02756 3e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
MLHAACIH_02757 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
MLHAACIH_02758 1.2e-221 epsD GT4 M Glycosyl transferase 4-like
MLHAACIH_02759 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MLHAACIH_02760 2.9e-218 epsF GT4 M Glycosyl transferases group 1
MLHAACIH_02761 5.4e-206 epsG S EpsG family
MLHAACIH_02762 2.9e-193 epsH GT2 S Glycosyltransferase like family 2
MLHAACIH_02763 1e-201 epsI GM pyruvyl transferase
MLHAACIH_02764 4.6e-191 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
MLHAACIH_02765 3.8e-255 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLHAACIH_02766 5.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MLHAACIH_02767 2.1e-56 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
MLHAACIH_02768 6.2e-221 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
MLHAACIH_02769 5.4e-186 yvfF GM Exopolysaccharide biosynthesis protein
MLHAACIH_02770 1e-31 yvfG S YvfG protein
MLHAACIH_02771 2.5e-242 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MLHAACIH_02772 5.7e-308 yvfH C L-lactate permease
MLHAACIH_02773 1e-112 yvfI K COG2186 Transcriptional regulators
MLHAACIH_02774 1.8e-184 lacR K Transcriptional regulator
MLHAACIH_02775 8.8e-229 cycB G COG2182 Maltose-binding periplasmic proteins domains
MLHAACIH_02776 1.1e-231 malC P COG1175 ABC-type sugar transport systems, permease components
MLHAACIH_02777 7.2e-150 ganQ P transport
MLHAACIH_02778 0.0 lacA 3.2.1.23 G beta-galactosidase
MLHAACIH_02779 3.2e-250 galA 3.2.1.89 G arabinogalactan
MLHAACIH_02780 1.5e-193 rsbU 3.1.3.3 T response regulator
MLHAACIH_02781 9.8e-157 rsbQ S Alpha/beta hydrolase family
MLHAACIH_02782 8.1e-160 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
MLHAACIH_02783 5.3e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
MLHAACIH_02784 7.1e-198 desK 2.7.13.3 T Histidine kinase
MLHAACIH_02785 2.6e-106 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLHAACIH_02786 2e-31 K Transcriptional regulator PadR-like family
MLHAACIH_02787 1.6e-45 S Protein of unknown function (DUF2812)
MLHAACIH_02788 6.5e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MLHAACIH_02789 1e-273 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
MLHAACIH_02790 1.5e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MLHAACIH_02791 4.7e-188 yvbX S Glycosyl hydrolase
MLHAACIH_02792 1.4e-240 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
MLHAACIH_02793 2.7e-155 yvbV EG EamA-like transporter family
MLHAACIH_02794 6.7e-159 yvbU K Transcriptional regulator
MLHAACIH_02795 5.8e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLHAACIH_02796 2.1e-202 araR K transcriptional
MLHAACIH_02797 4.8e-252 araE EGP Major facilitator Superfamily
MLHAACIH_02798 1.3e-182 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MLHAACIH_02799 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MLHAACIH_02800 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MLHAACIH_02801 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MLHAACIH_02802 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
MLHAACIH_02803 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MLHAACIH_02804 9.1e-75 yvbK 3.1.3.25 K acetyltransferase
MLHAACIH_02805 6.2e-252 tcaA S response to antibiotic
MLHAACIH_02806 2.2e-120 exoY M Membrane
MLHAACIH_02807 1.9e-112 yvbH S YvbH-like oligomerisation region
MLHAACIH_02808 6e-101 yvbG U UPF0056 membrane protein
MLHAACIH_02809 3.5e-97 yvbF K Belongs to the GbsR family
MLHAACIH_02810 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MLHAACIH_02811 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
MLHAACIH_02812 7.9e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MLHAACIH_02813 8.7e-114 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
MLHAACIH_02814 4.5e-45 sdpR K transcriptional
MLHAACIH_02815 3.3e-96 sdpI S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
MLHAACIH_02816 4.4e-08
MLHAACIH_02817 4.9e-171
MLHAACIH_02818 7.9e-13 S Sporulation delaying protein SdpA
MLHAACIH_02819 7.4e-60 yvbF K Belongs to the GbsR family
MLHAACIH_02820 2.7e-208 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MLHAACIH_02821 1.6e-109 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
MLHAACIH_02822 4.2e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MLHAACIH_02823 1.5e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
MLHAACIH_02824 2.2e-170 NT chemotaxis protein
MLHAACIH_02825 1.2e-19 NT chemotaxis protein
MLHAACIH_02826 2.2e-54 yodB K transcriptional
MLHAACIH_02827 1.5e-68 yvaO K Cro/C1-type HTH DNA-binding domain
MLHAACIH_02828 4e-69 K transcriptional
MLHAACIH_02829 9.8e-36 yvzC K Transcriptional
MLHAACIH_02830 1.5e-151 yvaM S Serine aminopeptidase, S33
MLHAACIH_02831 2.4e-23 secG U Preprotein translocase subunit SecG
MLHAACIH_02832 9.6e-143 est 3.1.1.1 S Carboxylesterase
MLHAACIH_02833 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MLHAACIH_02834 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MLHAACIH_02836 8.5e-129 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MLHAACIH_02837 4.3e-98 K Bacterial regulatory proteins, tetR family
MLHAACIH_02838 2.4e-54 yvaE P Small Multidrug Resistance protein
MLHAACIH_02839 1.3e-72 yvaD S Family of unknown function (DUF5360)
MLHAACIH_02840 0.0 yvaC S Fusaric acid resistance protein-like
MLHAACIH_02841 7e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MLHAACIH_02842 4e-195 yvaA 1.1.1.371 S Oxidoreductase
MLHAACIH_02843 2.2e-48 csoR S transcriptional
MLHAACIH_02844 5.9e-29 copZ P Copper resistance protein CopZ
MLHAACIH_02845 0.0 copA 3.6.3.54 P P-type ATPase
MLHAACIH_02846 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
MLHAACIH_02847 2.7e-104 bdbD O Thioredoxin
MLHAACIH_02848 8.5e-72 bdbC O Required for disulfide bond formation in some proteins
MLHAACIH_02849 4.1e-107 yvgT S membrane
MLHAACIH_02850 0.0 helD 3.6.4.12 L DNA helicase
MLHAACIH_02851 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MLHAACIH_02852 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
MLHAACIH_02853 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
MLHAACIH_02854 5.4e-86 yvgO
MLHAACIH_02855 3.2e-155 yvgN S reductase
MLHAACIH_02856 4e-119 modB P COG4149 ABC-type molybdate transport system, permease component
MLHAACIH_02857 1.4e-136 modA P COG0725 ABC-type molybdate transport system, periplasmic component
MLHAACIH_02858 2e-166 yvgK P COG1910 Periplasmic molybdate-binding protein domain
MLHAACIH_02859 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MLHAACIH_02860 2.3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
MLHAACIH_02861 6.5e-16 S Small spore protein J (Spore_SspJ)
MLHAACIH_02862 4.9e-236 yvsH E Arginine ornithine antiporter
MLHAACIH_02863 2.6e-177 fhuD P ABC transporter
MLHAACIH_02864 1.3e-180 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLHAACIH_02865 3.8e-174 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLHAACIH_02866 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
MLHAACIH_02867 6.9e-175 M Efflux transporter rnd family, mfp subunit
MLHAACIH_02868 2.1e-123 macB V ABC transporter, ATP-binding protein
MLHAACIH_02869 1.2e-209 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
MLHAACIH_02870 1.3e-64 yvrL S Regulatory protein YrvL
MLHAACIH_02871 1.4e-228 oxdC 4.1.1.2 G Oxalate decarboxylase
MLHAACIH_02872 6.9e-19 S YvrJ protein family
MLHAACIH_02873 4e-96 yvrI K RNA polymerase
MLHAACIH_02874 3.6e-22
MLHAACIH_02875 8.1e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLHAACIH_02876 0.0 T PhoQ Sensor
MLHAACIH_02877 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
MLHAACIH_02878 7.6e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MLHAACIH_02879 2.6e-169 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
MLHAACIH_02880 1.9e-184 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLHAACIH_02881 2.7e-244 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
MLHAACIH_02882 3.9e-99 yvqK 2.5.1.17 S Adenosyltransferase
MLHAACIH_02883 1.4e-226 yvqJ EGP Major facilitator Superfamily
MLHAACIH_02884 7.3e-62 liaI S membrane
MLHAACIH_02885 9.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
MLHAACIH_02886 1.2e-123 liaG S Putative adhesin
MLHAACIH_02887 1.2e-126 yvqF S Cell wall-active antibiotics response 4TMS YvqF
MLHAACIH_02888 1.6e-186 vraS 2.7.13.3 T Histidine kinase
MLHAACIH_02889 6.6e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLHAACIH_02890 5e-183 gerAC S Spore germination B3/ GerAC like, C-terminal
MLHAACIH_02891 3.8e-196 gerAB E Spore germination protein
MLHAACIH_02892 2.6e-245 gerAA EG Spore germination protein
MLHAACIH_02893 3.9e-24 S Protein of unknown function (DUF3970)
MLHAACIH_02894 9.6e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MLHAACIH_02895 4.8e-157 yuxN K Transcriptional regulator
MLHAACIH_02896 9.7e-250 cssS 2.7.13.3 T PhoQ Sensor
MLHAACIH_02897 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLHAACIH_02898 4.4e-234 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MLHAACIH_02899 2.7e-79 dps P Ferritin-like domain
MLHAACIH_02900 2e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MLHAACIH_02901 1.6e-300 pepF2 E COG1164 Oligoendopeptidase F
MLHAACIH_02902 3.3e-66 S YusW-like protein
MLHAACIH_02903 1e-153 yusV 3.6.3.34 HP ABC transporter
MLHAACIH_02904 6.6e-47 yusU S Protein of unknown function (DUF2573)
MLHAACIH_02905 8.2e-157 yusT K LysR substrate binding domain
MLHAACIH_02906 2.9e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MLHAACIH_02907 1.8e-63 yusQ S Tautomerase enzyme
MLHAACIH_02908 4.2e-292 yusP P Major facilitator superfamily
MLHAACIH_02909 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
MLHAACIH_02910 1.6e-52 yusN M Coat F domain
MLHAACIH_02911 5.1e-40
MLHAACIH_02912 1.2e-163 fadM E Proline dehydrogenase
MLHAACIH_02913 8.1e-09 S YuzL-like protein
MLHAACIH_02914 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
MLHAACIH_02915 3.2e-217 fadA 2.3.1.16 I Belongs to the thiolase family
MLHAACIH_02916 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
MLHAACIH_02917 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
MLHAACIH_02918 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MLHAACIH_02919 2.4e-39 yusG S Protein of unknown function (DUF2553)
MLHAACIH_02920 1.4e-72 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
MLHAACIH_02921 1.2e-54 traF CO Thioredoxin
MLHAACIH_02922 3.2e-56 yusD S SCP-2 sterol transfer family
MLHAACIH_02923 2.4e-184 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MLHAACIH_02924 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
MLHAACIH_02925 1.8e-145 metQ P Belongs to the NlpA lipoprotein family
MLHAACIH_02926 5.6e-46 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MLHAACIH_02927 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MLHAACIH_02928 9.1e-245 sufD O assembly protein SufD
MLHAACIH_02929 7.9e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MLHAACIH_02930 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
MLHAACIH_02931 3.5e-271 sufB O FeS cluster assembly
MLHAACIH_02932 3.6e-42 K helix_turn_helix, Arsenical Resistance Operon Repressor
MLHAACIH_02933 1.9e-65 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLHAACIH_02934 2.8e-62 L Molecular Function DNA binding, Biological Process DNA recombination
MLHAACIH_02935 1.1e-72 L Molecular Function DNA binding, Biological Process DNA recombination
MLHAACIH_02936 1e-41
MLHAACIH_02938 1.9e-206 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
MLHAACIH_02939 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
MLHAACIH_02940 5.7e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
MLHAACIH_02941 1.1e-62 yurO G COG1653 ABC-type sugar transport system, periplasmic component
MLHAACIH_02942 1.5e-152 yurO G COG1653 ABC-type sugar transport system, periplasmic component
MLHAACIH_02943 9e-148 yurL 2.7.1.218 G pfkB family carbohydrate kinase
MLHAACIH_02944 7.3e-135 yurK K UTRA
MLHAACIH_02945 1.5e-195 msmX P Belongs to the ABC transporter superfamily
MLHAACIH_02947 9e-80 I Fatty acid desaturase
MLHAACIH_02948 1.3e-22 I Fatty acid desaturase
MLHAACIH_02949 1.8e-170 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.2, 4.4.1.8 E methionine gamma-lyase
MLHAACIH_02950 4.1e-42 S B3/4 domain
MLHAACIH_02951 9.5e-67 L COG3666 Transposase and inactivated derivatives
MLHAACIH_02952 8.8e-36 L COG3666 Transposase and inactivated derivatives
MLHAACIH_02953 1.2e-157 gntR9 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLHAACIH_02954 9.3e-74 azlC E AzlC protein
MLHAACIH_02955 1.9e-23 S branched-chain amino acid
MLHAACIH_02956 3.8e-167 bsn L Ribonuclease
MLHAACIH_02957 2.2e-232 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MLHAACIH_02958 8.7e-237 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
MLHAACIH_02959 1.5e-186 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MLHAACIH_02960 1.2e-109 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
MLHAACIH_02961 4.3e-147 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
MLHAACIH_02962 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MLHAACIH_02963 9e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
MLHAACIH_02965 1e-54 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
MLHAACIH_02966 3.5e-277 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
MLHAACIH_02967 1.5e-220 pbuX F xanthine
MLHAACIH_02968 3.9e-235 pbuX F Permease family
MLHAACIH_02969 3.2e-300 pucR QT COG2508 Regulator of polyketide synthase expression
MLHAACIH_02970 6.2e-257 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
MLHAACIH_02971 6.6e-46 yunG
MLHAACIH_02972 1.3e-170 yunF S Protein of unknown function DUF72
MLHAACIH_02973 5.9e-141 yunE S membrane transporter protein
MLHAACIH_02974 1.6e-263 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
MLHAACIH_02975 9.2e-44 yunC S Domain of unknown function (DUF1805)
MLHAACIH_02976 6.6e-131 yunB S Sporulation protein YunB (Spo_YunB)
MLHAACIH_02977 1.3e-195 lytH M Peptidase, M23
MLHAACIH_02978 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MLHAACIH_02979 1.8e-110 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MLHAACIH_02980 1.1e-46 yutD S protein conserved in bacteria
MLHAACIH_02981 1e-75 yutE S Protein of unknown function DUF86
MLHAACIH_02982 3.2e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MLHAACIH_02983 5.6e-86 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
MLHAACIH_02984 8.5e-198 yutH S Spore coat protein
MLHAACIH_02985 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
MLHAACIH_02986 3.4e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MLHAACIH_02987 4.3e-172 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MLHAACIH_02988 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
MLHAACIH_02989 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
MLHAACIH_02990 1.1e-55 yuzD S protein conserved in bacteria
MLHAACIH_02991 7.7e-199 yutJ 1.6.99.3 C NADH dehydrogenase
MLHAACIH_02992 3.2e-39 yuzB S Belongs to the UPF0349 family
MLHAACIH_02993 1e-197 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MLHAACIH_02994 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MLHAACIH_02995 3.7e-63 erpA S Belongs to the HesB IscA family
MLHAACIH_02996 4.3e-49 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLHAACIH_02997 6.1e-114 paiB K Putative FMN-binding domain
MLHAACIH_02998 1.8e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MLHAACIH_03000 5e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
MLHAACIH_03001 1.6e-235 yumB 1.6.99.3 C NADH dehydrogenase
MLHAACIH_03002 1.1e-26 yuiB S Putative membrane protein
MLHAACIH_03003 6.8e-116 yuiC S protein conserved in bacteria
MLHAACIH_03004 2e-77 yuiD S protein conserved in bacteria
MLHAACIH_03005 2.2e-279 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MLHAACIH_03006 3.9e-211 yuiF S antiporter
MLHAACIH_03007 9.7e-93 bioY S Biotin biosynthesis protein
MLHAACIH_03008 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
MLHAACIH_03009 3.9e-167 besA S Putative esterase
MLHAACIH_03010 5.2e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MLHAACIH_03011 4.7e-224 entC 5.4.4.2 HQ Isochorismate synthase
MLHAACIH_03012 2.2e-311 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
MLHAACIH_03013 6.8e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
MLHAACIH_03014 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLHAACIH_03015 4.2e-35 mbtH S MbtH-like protein
MLHAACIH_03016 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
MLHAACIH_03017 2.6e-203 ald 1.4.1.1 E Belongs to the AlaDH PNT family
MLHAACIH_03018 2.8e-227 yukF QT Transcriptional regulator
MLHAACIH_03019 2.8e-45 esxA S Belongs to the WXG100 family
MLHAACIH_03020 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
MLHAACIH_03021 6.4e-209 essB S WXG100 protein secretion system (Wss), protein YukC
MLHAACIH_03022 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MLHAACIH_03023 0.0 esaA S type VII secretion protein EsaA
MLHAACIH_03024 6.6e-65 yueC S Family of unknown function (DUF5383)
MLHAACIH_03025 9.2e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLHAACIH_03026 1.1e-95 yueE S phosphohydrolase
MLHAACIH_03027 1.1e-23 S Protein of unknown function (DUF2642)
MLHAACIH_03028 5.2e-71 S Protein of unknown function (DUF2283)
MLHAACIH_03029 3.9e-188 yueF S transporter activity
MLHAACIH_03030 6.6e-31 yueG S Spore germination protein gerPA/gerPF
MLHAACIH_03031 6.3e-38 yueH S YueH-like protein
MLHAACIH_03032 3.6e-67 yueI S Protein of unknown function (DUF1694)
MLHAACIH_03033 7.3e-103 pncA Q COG1335 Amidases related to nicotinamidase
MLHAACIH_03034 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MLHAACIH_03035 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
MLHAACIH_03036 3.8e-23 yuzC
MLHAACIH_03038 1.5e-127 comQ H Belongs to the FPP GGPP synthase family
MLHAACIH_03040 0.0 comP 2.7.13.3 T Histidine kinase
MLHAACIH_03041 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLHAACIH_03042 1.8e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
MLHAACIH_03043 3.3e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
MLHAACIH_03044 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLHAACIH_03045 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLHAACIH_03046 3.9e-260 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLHAACIH_03047 3.4e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLHAACIH_03048 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLHAACIH_03049 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MLHAACIH_03050 5e-15
MLHAACIH_03051 1.3e-233 maeN C COG3493 Na citrate symporter
MLHAACIH_03052 6.6e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
MLHAACIH_03053 4.2e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
MLHAACIH_03054 2.7e-272 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
MLHAACIH_03055 1.7e-196 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
MLHAACIH_03056 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
MLHAACIH_03057 1.3e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MLHAACIH_03058 1.8e-77 yufK S Family of unknown function (DUF5366)
MLHAACIH_03059 1.8e-74 yuxK S protein conserved in bacteria
MLHAACIH_03060 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
MLHAACIH_03061 1.1e-184 yuxJ EGP Major facilitator Superfamily
MLHAACIH_03063 2.7e-114 kapD L the KinA pathway to sporulation
MLHAACIH_03064 4.1e-68 kapB G Kinase associated protein B
MLHAACIH_03065 1.7e-232 T PhoQ Sensor
MLHAACIH_03066 1.7e-226 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MLHAACIH_03067 4.6e-39 yugE S Domain of unknown function (DUF1871)
MLHAACIH_03068 4.9e-156 yugF I Hydrolase
MLHAACIH_03069 1.6e-85 alaR K Transcriptional regulator
MLHAACIH_03070 2.1e-199 yugH 2.6.1.1 E Aminotransferase
MLHAACIH_03071 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
MLHAACIH_03072 1.1e-34 yuzA S Domain of unknown function (DUF378)
MLHAACIH_03073 1.7e-226 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
MLHAACIH_03074 1.4e-228 yugK C Dehydrogenase
MLHAACIH_03075 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
MLHAACIH_03077 1.4e-71 yugN S YugN-like family
MLHAACIH_03078 8.2e-182 yugO P COG1226 Kef-type K transport systems
MLHAACIH_03079 1.2e-52 mstX S Membrane-integrating protein Mistic
MLHAACIH_03080 3.7e-36
MLHAACIH_03081 1.4e-116 yugP S Zn-dependent protease
MLHAACIH_03082 8.4e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
MLHAACIH_03083 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
MLHAACIH_03084 1.8e-24 yugU S Uncharacterised protein family UPF0047
MLHAACIH_03085 2.9e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
MLHAACIH_03086 1.5e-222 mcpA NT chemotaxis protein
MLHAACIH_03087 1.6e-211 mcpA NT chemotaxis protein
MLHAACIH_03088 1e-292 mcpA NT chemotaxis protein
MLHAACIH_03089 7.3e-238 mcpA NT chemotaxis protein
MLHAACIH_03090 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
MLHAACIH_03091 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
MLHAACIH_03092 2.5e-272 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
MLHAACIH_03093 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
MLHAACIH_03094 2.6e-252 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
MLHAACIH_03095 9.7e-183 ygjR S Oxidoreductase
MLHAACIH_03096 1.3e-194 yubA S transporter activity
MLHAACIH_03097 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MLHAACIH_03099 1.3e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
MLHAACIH_03100 2.7e-272 yubD P Major Facilitator Superfamily
MLHAACIH_03101 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MLHAACIH_03102 1e-38 yiaA S yiaA/B two helix domain
MLHAACIH_03103 1.6e-236 ktrB P Potassium
MLHAACIH_03104 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
MLHAACIH_03105 6e-44 tnpIS3 L Transposase
MLHAACIH_03106 2.2e-91 yuaB
MLHAACIH_03107 5.5e-95 yuaC K Belongs to the GbsR family
MLHAACIH_03108 1.2e-280 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
MLHAACIH_03109 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
MLHAACIH_03110 4.8e-105 yuaD
MLHAACIH_03111 3.3e-83 yuaE S DinB superfamily
MLHAACIH_03112 1.9e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
MLHAACIH_03113 2e-187 yuaG 3.4.21.72 S protein conserved in bacteria
MLHAACIH_03114 3.4e-94 M1-753 M FR47-like protein
MLHAACIH_03115 5.7e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
MLHAACIH_03122 1.3e-09
MLHAACIH_03123 7.8e-08
MLHAACIH_03132 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MLHAACIH_03133 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MLHAACIH_03134 2.9e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
MLHAACIH_03135 2.9e-284 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
MLHAACIH_03136 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MLHAACIH_03137 9.9e-77 tspO T membrane
MLHAACIH_03138 8.2e-204 cotI S Spore coat protein
MLHAACIH_03139 3.4e-216 cotSA M Glycosyl transferases group 1
MLHAACIH_03140 1.5e-205 cotS S Seems to be required for the assembly of the CotSA protein in spores
MLHAACIH_03142 1.8e-226 ytcC M Glycosyltransferase Family 4
MLHAACIH_03143 3.4e-177 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
MLHAACIH_03144 5.8e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MLHAACIH_03145 7.4e-152 galU 2.7.7.9 M Nucleotidyl transferase
MLHAACIH_03146 9.7e-132 dksA T COG1734 DnaK suppressor protein
MLHAACIH_03147 1.1e-269 menF 5.4.4.2 HQ Isochorismate synthase
MLHAACIH_03148 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MLHAACIH_03149 1.7e-151 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MLHAACIH_03150 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MLHAACIH_03151 2.4e-270 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MLHAACIH_03152 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MLHAACIH_03153 1.1e-169 troA P Belongs to the bacterial solute-binding protein 9 family
MLHAACIH_03154 4.5e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MLHAACIH_03155 1.8e-229 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MLHAACIH_03156 2.6e-150 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
MLHAACIH_03157 4.3e-24 S Domain of Unknown Function (DUF1540)
MLHAACIH_03158 5.2e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
MLHAACIH_03159 6.8e-248 cydA 1.10.3.14 C oxidase, subunit
MLHAACIH_03160 6.1e-41 rpmE2 J Ribosomal protein L31
MLHAACIH_03161 9.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
MLHAACIH_03162 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MLHAACIH_03163 1.1e-72 ytkA S YtkA-like
MLHAACIH_03165 2.1e-76 dps P Belongs to the Dps family
MLHAACIH_03166 1.7e-61 ytkC S Bacteriophage holin family
MLHAACIH_03167 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
MLHAACIH_03168 6.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MLHAACIH_03169 1.4e-144 ytlC P ABC transporter
MLHAACIH_03170 2.8e-188 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MLHAACIH_03171 1.1e-146 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
MLHAACIH_03172 4.7e-38 ytmB S Protein of unknown function (DUF2584)
MLHAACIH_03173 2.8e-309 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MLHAACIH_03174 1.4e-223 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MLHAACIH_03175 0.0 asnB 6.3.5.4 E Asparagine synthase
MLHAACIH_03176 1.7e-254 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
MLHAACIH_03177 2.7e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MLHAACIH_03178 9.5e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
MLHAACIH_03179 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
MLHAACIH_03180 7.4e-106 ytqB J Putative rRNA methylase
MLHAACIH_03181 8.1e-190 yhcC S Fe-S oxidoreductase
MLHAACIH_03182 1.5e-40 ytzC S Protein of unknown function (DUF2524)
MLHAACIH_03184 5.1e-66 ytrA K GntR family transcriptional regulator
MLHAACIH_03185 4.2e-161 ytrB P abc transporter atp-binding protein
MLHAACIH_03186 2.1e-07 P ABC-2 family transporter protein
MLHAACIH_03187 1.2e-116 P ABC-2 family transporter protein
MLHAACIH_03188 1.7e-147
MLHAACIH_03189 9.1e-127 ytrE V ABC transporter, ATP-binding protein
MLHAACIH_03190 1.9e-234 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
MLHAACIH_03191 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLHAACIH_03192 4.9e-182 T PhoQ Sensor
MLHAACIH_03193 4.8e-137 bceA V ABC transporter, ATP-binding protein
MLHAACIH_03194 0.0 bceB V ABC transporter (permease)
MLHAACIH_03195 1.8e-43 yttA 2.7.13.3 S Pfam Transposase IS66
MLHAACIH_03196 1e-210 yttB EGP Major facilitator Superfamily
MLHAACIH_03197 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
MLHAACIH_03198 7.7e-55 ytvB S Protein of unknown function (DUF4257)
MLHAACIH_03199 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MLHAACIH_03200 2.1e-51 ytwF P Sulfurtransferase
MLHAACIH_03201 3.4e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
MLHAACIH_03202 4.4e-144 amyC P ABC transporter (permease)
MLHAACIH_03203 6.2e-168 amyD P ABC transporter
MLHAACIH_03204 7.3e-247 msmE G Bacterial extracellular solute-binding protein
MLHAACIH_03205 1.8e-187 msmR K Transcriptional regulator
MLHAACIH_03206 1.9e-172 ytaP S Acetyl xylan esterase (AXE1)
MLHAACIH_03207 2.9e-139 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MLHAACIH_03208 1.6e-257 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
MLHAACIH_03209 4.3e-214 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MLHAACIH_03210 3.8e-125 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MLHAACIH_03211 6.4e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MLHAACIH_03212 2.4e-220 bioI 1.14.14.46 C Cytochrome P450
MLHAACIH_03213 6.2e-137 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
MLHAACIH_03214 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
MLHAACIH_03215 9.3e-286 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
MLHAACIH_03216 3.3e-135 ytdP K Transcriptional regulator
MLHAACIH_03217 9.5e-278 ytdP K Transcriptional regulator
MLHAACIH_03218 5e-65 lplB G COG4209 ABC-type polysaccharide transport system, permease component
MLHAACIH_03219 4.2e-95 lplB G COG4209 ABC-type polysaccharide transport system, permease component
MLHAACIH_03220 2.5e-219 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
MLHAACIH_03221 5.6e-71 yteS G transport
MLHAACIH_03222 8.5e-198 yteT S Oxidoreductase family, C-terminal alpha/beta domain
MLHAACIH_03223 7e-76 yteU S Integral membrane protein
MLHAACIH_03224 3.1e-26 yteV S Sporulation protein Cse60
MLHAACIH_03225 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
MLHAACIH_03226 9e-231 ytfP S HI0933-like protein
MLHAACIH_03227 2.5e-292 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLHAACIH_03228 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MLHAACIH_03229 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
MLHAACIH_03230 4.8e-131 ythP V ABC transporter
MLHAACIH_03231 1.7e-202 ythQ U Bacterial ABC transporter protein EcsB
MLHAACIH_03232 2.1e-225 pbuO S permease
MLHAACIH_03233 3.9e-270 pepV 3.5.1.18 E Dipeptidase
MLHAACIH_03234 1.5e-172 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MLHAACIH_03235 3e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MLHAACIH_03236 2.2e-165 ytlQ
MLHAACIH_03237 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
MLHAACIH_03238 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
MLHAACIH_03239 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
MLHAACIH_03240 2e-45 ytzH S YtzH-like protein
MLHAACIH_03241 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MLHAACIH_03242 2.7e-149 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
MLHAACIH_03243 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
MLHAACIH_03244 2.2e-51 ytzB S small secreted protein
MLHAACIH_03245 1.3e-204 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
MLHAACIH_03246 3.5e-21 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
MLHAACIH_03247 6.7e-48 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
MLHAACIH_03248 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MLHAACIH_03249 4.8e-148 ytpQ S Belongs to the UPF0354 family
MLHAACIH_03250 2.8e-108 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MLHAACIH_03251 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
MLHAACIH_03252 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MLHAACIH_03253 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MLHAACIH_03254 6.6e-17 ytxH S COG4980 Gas vesicle protein
MLHAACIH_03255 2.8e-54 ytxJ O Protein of unknown function (DUF2847)
MLHAACIH_03256 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MLHAACIH_03257 3.8e-182 ccpA K catabolite control protein A
MLHAACIH_03258 2.1e-146 motA N flagellar motor
MLHAACIH_03259 5.2e-125 motS N Flagellar motor protein
MLHAACIH_03260 5.4e-225 acuC BQ histone deacetylase
MLHAACIH_03261 3.5e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
MLHAACIH_03262 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MLHAACIH_03263 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MLHAACIH_03264 6.7e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MLHAACIH_03266 5.4e-79 L Integrase core domain
MLHAACIH_03267 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MLHAACIH_03268 1.1e-306 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
MLHAACIH_03269 2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
MLHAACIH_03270 6.5e-108 yttP K Transcriptional regulator
MLHAACIH_03271 1.9e-152 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
MLHAACIH_03272 4.6e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MLHAACIH_03273 1.4e-237 brnQ E Component of the transport system for branched-chain amino acids
MLHAACIH_03274 9.2e-209 iscS2 2.8.1.7 E Cysteine desulfurase
MLHAACIH_03275 1e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MLHAACIH_03276 2.2e-28 sspB S spore protein
MLHAACIH_03277 1.2e-304 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MLHAACIH_03278 0.0 ytcJ S amidohydrolase
MLHAACIH_03279 6.3e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MLHAACIH_03280 1.1e-178 sppA OU signal peptide peptidase SppA
MLHAACIH_03281 1.5e-86 yteJ S RDD family
MLHAACIH_03282 9.6e-108 ytfI S Protein of unknown function (DUF2953)
MLHAACIH_03283 1.5e-66 ytfJ S Sporulation protein YtfJ
MLHAACIH_03284 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MLHAACIH_03285 3.3e-162 ytxK 2.1.1.72 L DNA methylase
MLHAACIH_03286 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MLHAACIH_03287 3e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
MLHAACIH_03288 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MLHAACIH_03289 5.8e-266 argH 4.3.2.1 E argininosuccinate lyase
MLHAACIH_03291 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLHAACIH_03292 3.9e-130 ytkL S Belongs to the UPF0173 family
MLHAACIH_03293 2.9e-173 ytlI K LysR substrate binding domain
MLHAACIH_03294 4.7e-99 ytmI K Acetyltransferase (GNAT) domain
MLHAACIH_03295 2.1e-151 tcyK ET Bacterial periplasmic substrate-binding proteins
MLHAACIH_03296 1.3e-145 tcyK M Bacterial periplasmic substrate-binding proteins
MLHAACIH_03297 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
MLHAACIH_03298 6.4e-120 tcyM U Binding-protein-dependent transport system inner membrane component
MLHAACIH_03299 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MLHAACIH_03300 1.2e-183 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLHAACIH_03301 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
MLHAACIH_03302 2e-255 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLHAACIH_03303 1.4e-127 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
MLHAACIH_03304 6.8e-186 ytnL 3.5.1.47 E hydrolase activity
MLHAACIH_03305 2.3e-154 ytnM S membrane transporter protein
MLHAACIH_03306 2.3e-240 ytoI K transcriptional regulator containing CBS domains
MLHAACIH_03307 2.4e-47 ytpI S YtpI-like protein
MLHAACIH_03308 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
MLHAACIH_03309 9.2e-29
MLHAACIH_03310 8.2e-69 ytrI
MLHAACIH_03311 3.2e-56 ytrH S Sporulation protein YtrH
MLHAACIH_03312 0.0 dnaE 2.7.7.7 L DNA polymerase
MLHAACIH_03313 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
MLHAACIH_03314 3.2e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MLHAACIH_03315 7.4e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MLHAACIH_03316 2.8e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MLHAACIH_03317 4.9e-311 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MLHAACIH_03318 3.3e-62 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
MLHAACIH_03319 5.8e-192 ytvI S sporulation integral membrane protein YtvI
MLHAACIH_03320 4.7e-71 yeaL S membrane
MLHAACIH_03321 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
MLHAACIH_03322 4.1e-242 icd 1.1.1.42 C isocitrate
MLHAACIH_03323 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
MLHAACIH_03324 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLHAACIH_03325 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
MLHAACIH_03326 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MLHAACIH_03327 3.3e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MLHAACIH_03328 1.1e-107 ytaF P Probably functions as a manganese efflux pump
MLHAACIH_03329 2.9e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MLHAACIH_03330 1.7e-159 ytbE S reductase
MLHAACIH_03331 3.3e-201 ytbD EGP Major facilitator Superfamily
MLHAACIH_03332 6.5e-15 ytcD K Transcriptional regulator
MLHAACIH_03333 2.8e-41 ytcD K Transcriptional regulator
MLHAACIH_03334 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MLHAACIH_03335 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MLHAACIH_03336 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MLHAACIH_03337 7.7e-266 dnaB L Membrane attachment protein
MLHAACIH_03338 3e-173 dnaI L Primosomal protein DnaI
MLHAACIH_03339 1.6e-109 ytxB S SNARE associated Golgi protein
MLHAACIH_03340 1.6e-157 ytxC S YtxC-like family
MLHAACIH_03342 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MLHAACIH_03343 5.2e-147 ysaA S HAD-hyrolase-like
MLHAACIH_03344 0.0 lytS 2.7.13.3 T Histidine kinase
MLHAACIH_03345 3.1e-130 lytT T COG3279 Response regulator of the LytR AlgR family
MLHAACIH_03346 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MLHAACIH_03347 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MLHAACIH_03349 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MLHAACIH_03350 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MLHAACIH_03351 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MLHAACIH_03352 7.5e-45 ysdA S Membrane
MLHAACIH_03353 9.2e-68 ysdB S Sigma-w pathway protein YsdB
MLHAACIH_03354 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
MLHAACIH_03355 4e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
MLHAACIH_03356 1e-292 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
MLHAACIH_03357 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
MLHAACIH_03358 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MLHAACIH_03359 2.3e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
MLHAACIH_03360 3.1e-220 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
MLHAACIH_03361 5.8e-252 araN G carbohydrate transport
MLHAACIH_03362 4.2e-167 araP G carbohydrate transport
MLHAACIH_03363 9.9e-144 araQ G transport system permease
MLHAACIH_03364 1e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
MLHAACIH_03365 0.0 cstA T Carbon starvation protein
MLHAACIH_03367 6.2e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
MLHAACIH_03368 8.3e-254 glcF C Glycolate oxidase
MLHAACIH_03369 3.1e-259 glcD 1.1.3.15 C Glycolate oxidase subunit
MLHAACIH_03370 5.9e-205 ysfB KT regulator
MLHAACIH_03371 2.6e-32 sspI S Belongs to the SspI family
MLHAACIH_03372 1.1e-130 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MLHAACIH_03373 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MLHAACIH_03374 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MLHAACIH_03375 2.4e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MLHAACIH_03376 2e-39 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MLHAACIH_03377 1.7e-85 cvpA S membrane protein, required for colicin V production
MLHAACIH_03378 0.0 polX L COG1796 DNA polymerase IV (family X)
MLHAACIH_03379 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MLHAACIH_03380 7.3e-68 yshE S membrane
MLHAACIH_03381 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MLHAACIH_03382 4e-99 fadR K Transcriptional regulator
MLHAACIH_03383 3.5e-135 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
MLHAACIH_03384 3.8e-134 etfB C Electron transfer flavoprotein
MLHAACIH_03385 5.1e-176 etfA C Electron transfer flavoprotein
MLHAACIH_03387 4.1e-302 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
MLHAACIH_03388 2e-52 trxA O Belongs to the thioredoxin family
MLHAACIH_03389 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MLHAACIH_03390 2.7e-214 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
MLHAACIH_03391 1.2e-79 yslB S Protein of unknown function (DUF2507)
MLHAACIH_03392 2.4e-107 sdhC C succinate dehydrogenase
MLHAACIH_03393 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
MLHAACIH_03394 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
MLHAACIH_03395 6.5e-78 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
MLHAACIH_03396 3.3e-30 gerE K Transcriptional regulator
MLHAACIH_03397 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
MLHAACIH_03398 3.9e-153 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MLHAACIH_03399 2.9e-196 gerM S COG5401 Spore germination protein
MLHAACIH_03400 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MLHAACIH_03401 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MLHAACIH_03402 4.1e-92 ysnB S Phosphoesterase
MLHAACIH_03404 3.8e-132 ysnF S protein conserved in bacteria
MLHAACIH_03405 1.8e-78 ysnE K acetyltransferase
MLHAACIH_03407 0.0 ilvB 2.2.1.6 E Acetolactate synthase
MLHAACIH_03408 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
MLHAACIH_03409 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MLHAACIH_03410 4.2e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MLHAACIH_03411 5.7e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MLHAACIH_03412 1.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MLHAACIH_03413 2.6e-114 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MLHAACIH_03414 5.1e-187 ysoA H Tetratricopeptide repeat
MLHAACIH_03415 1.6e-225 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MLHAACIH_03416 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MLHAACIH_03417 1.1e-310 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
MLHAACIH_03418 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MLHAACIH_03419 5.7e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
MLHAACIH_03420 1.4e-89 ysxD
MLHAACIH_03421 4.6e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MLHAACIH_03422 3.6e-146 hemX O cytochrome C
MLHAACIH_03423 1.5e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MLHAACIH_03424 1.3e-142 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
MLHAACIH_03425 2.8e-182 hemB 4.2.1.24 H Belongs to the ALAD family
MLHAACIH_03426 1.5e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
MLHAACIH_03427 2.5e-103 spoVID M stage VI sporulation protein D
MLHAACIH_03428 5e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MLHAACIH_03429 1.6e-25
MLHAACIH_03430 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MLHAACIH_03431 4.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MLHAACIH_03432 2.5e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MLHAACIH_03433 2.3e-163 spoIIB S Sporulation related domain
MLHAACIH_03434 2.8e-102 maf D septum formation protein Maf
MLHAACIH_03435 9.8e-68 radC E Belongs to the UPF0758 family
MLHAACIH_03436 6e-226 S Recombinase
MLHAACIH_03437 9.2e-72 S Pfam:Peptidase_M78
MLHAACIH_03438 6.8e-64 S sequence-specific DNA binding
MLHAACIH_03439 8.8e-09 plcR K helix-turn-helix
MLHAACIH_03442 1.3e-48
MLHAACIH_03444 4.6e-163 L Protein of unknown function (DUF2800)
MLHAACIH_03445 1.4e-85 S Protein of unknown function (DUF2815)
MLHAACIH_03447 8.4e-19
MLHAACIH_03448 8.3e-303 2.7.7.7 L DNA polymerase A domain
MLHAACIH_03451 0.0 L Virulence-associated protein E
MLHAACIH_03452 1.4e-32 S VRR_NUC
MLHAACIH_03453 4.7e-228 KL SNF2 family N-terminal domain
MLHAACIH_03454 6.6e-47
MLHAACIH_03455 2.8e-50
MLHAACIH_03457 1.1e-49 V HNH endonuclease
MLHAACIH_03458 4e-79 L phage terminase small subunit
MLHAACIH_03459 2.7e-305 S Terminase
MLHAACIH_03461 6.3e-238 S Phage portal protein
MLHAACIH_03462 7.8e-121 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
MLHAACIH_03463 3.6e-206 S capsid protein
MLHAACIH_03464 3.9e-17
MLHAACIH_03465 3.4e-38 S Phage gp6-like head-tail connector protein
MLHAACIH_03466 4.7e-38 S Phage head-tail joining protein
MLHAACIH_03467 1e-50 S Bacteriophage HK97-gp10, putative tail-component
MLHAACIH_03469 1.1e-75 S Phage tail tube protein
MLHAACIH_03472 0.0 D phage tail tape measure protein
MLHAACIH_03473 1.7e-111 S Phage tail protein
MLHAACIH_03474 3.6e-217 NU Prophage endopeptidase tail
MLHAACIH_03475 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
MLHAACIH_03476 3.6e-142 S Domain of unknown function (DUF2479)
MLHAACIH_03479 5e-28 bhlA S BhlA holin family
MLHAACIH_03480 2.1e-31 xhlB S SPP1 phage holin
MLHAACIH_03482 4.4e-112 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
MLHAACIH_03483 8.3e-67 S Immunity protein 70
MLHAACIH_03484 1.1e-178 A Pre-toxin TG
MLHAACIH_03485 9.2e-12 S Membrane
MLHAACIH_03488 2.1e-27 K Helix-turn-helix domain
MLHAACIH_03491 5.4e-51 radC E Belongs to the UPF0758 family
MLHAACIH_03492 1.8e-184 mreB D Rod shape-determining protein MreB
MLHAACIH_03493 1.1e-156 mreC M Involved in formation and maintenance of cell shape
MLHAACIH_03494 1.4e-84 mreD M shape-determining protein
MLHAACIH_03495 7.1e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MLHAACIH_03496 4.7e-143 minD D Belongs to the ParA family
MLHAACIH_03497 1.1e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
MLHAACIH_03498 2e-160 spoIVFB S Stage IV sporulation protein
MLHAACIH_03499 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
MLHAACIH_03500 4.1e-56 ysxB J ribosomal protein
MLHAACIH_03501 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MLHAACIH_03502 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
MLHAACIH_03503 4.3e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MLHAACIH_03504 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
MLHAACIH_03505 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
MLHAACIH_03506 2.3e-93 niaR S small molecule binding protein (contains 3H domain)
MLHAACIH_03507 5.9e-227 nifS 2.8.1.7 E Cysteine desulfurase
MLHAACIH_03508 3.2e-300 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
MLHAACIH_03509 3.4e-155 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
MLHAACIH_03510 9.1e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MLHAACIH_03511 2.6e-134 safA M spore coat assembly protein SafA
MLHAACIH_03512 6e-47 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MLHAACIH_03513 6.1e-126 yebC K transcriptional regulatory protein
MLHAACIH_03514 8.5e-260 alsT E Sodium alanine symporter
MLHAACIH_03515 4e-51 S Family of unknown function (DUF5412)
MLHAACIH_03517 6.5e-119 yrzF T serine threonine protein kinase
MLHAACIH_03518 1.3e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
MLHAACIH_03519 5.3e-253 csbX EGP Major facilitator Superfamily
MLHAACIH_03520 4.8e-93 bofC S BofC C-terminal domain
MLHAACIH_03521 4.5e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MLHAACIH_03522 1.9e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MLHAACIH_03523 2.6e-18 yrzS S Protein of unknown function (DUF2905)
MLHAACIH_03524 5.7e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MLHAACIH_03525 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MLHAACIH_03526 8e-39 yajC U Preprotein translocase subunit YajC
MLHAACIH_03527 3.8e-73 yrzE S Protein of unknown function (DUF3792)
MLHAACIH_03528 6.6e-111 yrbG S membrane
MLHAACIH_03529 2.4e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLHAACIH_03530 9.4e-49 yrzD S Post-transcriptional regulator
MLHAACIH_03531 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MLHAACIH_03532 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
MLHAACIH_03533 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
MLHAACIH_03534 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MLHAACIH_03535 2.3e-90 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MLHAACIH_03536 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MLHAACIH_03537 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MLHAACIH_03538 1.1e-260 lytH 3.5.1.28 M COG3103 SH3 domain protein
MLHAACIH_03540 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
MLHAACIH_03541 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MLHAACIH_03542 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MLHAACIH_03543 1.7e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MLHAACIH_03544 1.2e-70 cymR K Transcriptional regulator
MLHAACIH_03545 2e-211 iscS 2.8.1.7 E Cysteine desulfurase
MLHAACIH_03546 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MLHAACIH_03547 1.4e-15 S COG0457 FOG TPR repeat
MLHAACIH_03548 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MLHAACIH_03549 6.6e-81 yrrD S protein conserved in bacteria
MLHAACIH_03550 9.8e-31 yrzR
MLHAACIH_03551 8e-08 S Protein of unknown function (DUF3918)
MLHAACIH_03552 7.6e-107 glnP P ABC transporter
MLHAACIH_03553 2.3e-108 gluC P ABC transporter
MLHAACIH_03554 2.5e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
MLHAACIH_03555 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MLHAACIH_03556 2.5e-168 yrrI S AI-2E family transporter
MLHAACIH_03557 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MLHAACIH_03558 1.7e-41 yrzL S Belongs to the UPF0297 family
MLHAACIH_03559 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MLHAACIH_03560 1.2e-45 yrzB S Belongs to the UPF0473 family
MLHAACIH_03561 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MLHAACIH_03562 2.3e-119 yrrM 2.1.1.104 S O-methyltransferase
MLHAACIH_03563 7.8e-174 yegQ O Peptidase U32
MLHAACIH_03564 1.4e-245 yegQ O COG0826 Collagenase and related proteases
MLHAACIH_03565 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
MLHAACIH_03566 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MLHAACIH_03567 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
MLHAACIH_03568 4.2e-63 yrrS S Protein of unknown function (DUF1510)
MLHAACIH_03569 3.5e-26 yrzA S Protein of unknown function (DUF2536)
MLHAACIH_03570 1.2e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
MLHAACIH_03571 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MLHAACIH_03572 1.2e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
MLHAACIH_03573 7.5e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MLHAACIH_03574 4.6e-35 yrhC S YrhC-like protein
MLHAACIH_03575 7.1e-78 yrhD S Protein of unknown function (DUF1641)
MLHAACIH_03576 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
MLHAACIH_03577 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
MLHAACIH_03579 3e-142 focA P Formate nitrite
MLHAACIH_03582 1e-93 yrhH Q methyltransferase
MLHAACIH_03583 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
MLHAACIH_03584 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
MLHAACIH_03585 9e-44 yrhK S YrhK-like protein
MLHAACIH_03586 0.0 yrhL I Acyltransferase family
MLHAACIH_03587 7.2e-150 rsiV S Protein of unknown function (DUF3298)
MLHAACIH_03588 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
MLHAACIH_03589 1.1e-150 yrhO K Archaeal transcriptional regulator TrmB
MLHAACIH_03590 3.1e-105 yrhP E LysE type translocator
MLHAACIH_03591 3.3e-253 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
MLHAACIH_03592 0.0 levR K PTS system fructose IIA component
MLHAACIH_03593 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
MLHAACIH_03594 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
MLHAACIH_03595 4.4e-117 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
MLHAACIH_03596 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
MLHAACIH_03597 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
MLHAACIH_03598 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
MLHAACIH_03599 2.4e-195 adhA 1.1.1.1 C alcohol dehydrogenase
MLHAACIH_03600 4.4e-47 yraB K helix_turn_helix, mercury resistance
MLHAACIH_03601 1.1e-22 yraD M Spore coat protein
MLHAACIH_03602 1.2e-12 yraD M Spore coat protein
MLHAACIH_03603 7.5e-26 yraE
MLHAACIH_03604 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MLHAACIH_03605 1.9e-62 yraF M Spore coat protein
MLHAACIH_03606 1.5e-36 yraG
MLHAACIH_03607 1.4e-65 E Glyoxalase-like domain
MLHAACIH_03608 3.4e-61 T sh3 domain protein
MLHAACIH_03609 1.7e-60 T sh3 domain protein
MLHAACIH_03610 4.7e-151 S Alpha beta hydrolase
MLHAACIH_03611 3.2e-37 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLHAACIH_03612 1.1e-14 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
MLHAACIH_03613 5.9e-205 yraM S PrpF protein
MLHAACIH_03614 3.4e-163 yraN K Transcriptional regulator
MLHAACIH_03615 9.5e-226 yraO C Citrate transporter
MLHAACIH_03616 1.7e-187 yrpG C Aldo/keto reductase family
MLHAACIH_03617 1.2e-91 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
MLHAACIH_03618 1.3e-113 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
MLHAACIH_03620 4.8e-123 yrpD S Domain of unknown function, YrpD
MLHAACIH_03621 3.1e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MLHAACIH_03622 8.4e-193 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MLHAACIH_03623 5.1e-164 aadK G Streptomycin adenylyltransferase
MLHAACIH_03624 6.4e-90 yrdA S DinB family
MLHAACIH_03626 1.9e-57 S Protein of unknown function (DUF2568)
MLHAACIH_03627 1.2e-100 yrdC 3.5.1.19 Q Isochorismatase family
MLHAACIH_03628 4.2e-23 K Acetyltransferase (GNAT) family
MLHAACIH_03629 2.1e-227 cypA C Cytochrome P450
MLHAACIH_03630 9.7e-40 yrdF K ribonuclease inhibitor
MLHAACIH_03631 1.1e-78 bkdR K helix_turn_helix ASNC type
MLHAACIH_03632 2.2e-91 azlC E AzlC protein
MLHAACIH_03633 5.6e-50 azlD E Branched-chain amino acid transport protein (AzlD)
MLHAACIH_03634 1.1e-226 brnQ E Component of the transport system for branched-chain amino acids
MLHAACIH_03635 5e-162 gltR K LysR substrate binding domain
MLHAACIH_03636 4.2e-65 yodA S tautomerase
MLHAACIH_03637 7.5e-75 czcD P COG1230 Co Zn Cd efflux system component
MLHAACIH_03638 2.2e-68 czcD P COG1230 Co Zn Cd efflux system component
MLHAACIH_03639 3.6e-196 trkA P Oxidoreductase
MLHAACIH_03640 6.6e-159 yrdQ K Transcriptional regulator
MLHAACIH_03641 1.9e-170 yrdR EG EamA-like transporter family
MLHAACIH_03642 3.9e-16 S YrzO-like protein
MLHAACIH_03643 1.1e-234 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MLHAACIH_03644 1.5e-82 bltD 2.3.1.57 K FR47-like protein
MLHAACIH_03645 2.3e-210 blt EGP Major facilitator Superfamily
MLHAACIH_03646 3.1e-150 bltR K helix_turn_helix, mercury resistance
MLHAACIH_03647 1.8e-104 yrkC G Cupin domain
MLHAACIH_03648 8.6e-21
MLHAACIH_03649 7.8e-39 yrkD S protein conserved in bacteria
MLHAACIH_03650 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
MLHAACIH_03651 4.2e-98 yrkF OP Belongs to the sulfur carrier protein TusA family
MLHAACIH_03652 4.7e-16 perX S Sulfur reduction protein DsrE
MLHAACIH_03653 9.3e-206 yrkH P Rhodanese Homology Domain
MLHAACIH_03654 5.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
MLHAACIH_03655 2.1e-111 yrkJ S membrane transporter protein
MLHAACIH_03656 6e-165 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
MLHAACIH_03657 5.3e-70 mepA V Multidrug transporter MatE
MLHAACIH_03658 1.9e-118 mepA V Multidrug transporter MatE
MLHAACIH_03659 3.3e-113 tetR3 K Transcriptional regulator
MLHAACIH_03660 2.2e-12 K Helix-turn-helix XRE-family like proteins
MLHAACIH_03661 1.9e-44 M D-alanyl-D-alanine carboxypeptidase
MLHAACIH_03665 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLHAACIH_03666 1.6e-35 nucB M Deoxyribonuclease NucA/NucB
MLHAACIH_03667 6.3e-131 yqeB
MLHAACIH_03668 5e-170 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
MLHAACIH_03669 8.8e-105 yqeD S SNARE associated Golgi protein
MLHAACIH_03670 7e-133 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MLHAACIH_03671 1.4e-141 yqeF E GDSL-like Lipase/Acylhydrolase
MLHAACIH_03673 5.3e-95 yqeG S hydrolase of the HAD superfamily
MLHAACIH_03674 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MLHAACIH_03675 3.3e-155 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MLHAACIH_03676 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
MLHAACIH_03677 3.8e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MLHAACIH_03678 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
MLHAACIH_03679 9.9e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MLHAACIH_03680 1.4e-138 yqeM Q Methyltransferase
MLHAACIH_03681 2.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MLHAACIH_03682 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
MLHAACIH_03683 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
MLHAACIH_03684 0.0 comEC S Competence protein ComEC
MLHAACIH_03685 4.1e-15 S YqzM-like protein
MLHAACIH_03686 6.2e-188 holA 2.7.7.7 L DNA polymerase III delta subunit
MLHAACIH_03687 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
MLHAACIH_03688 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MLHAACIH_03689 1.5e-222 spoIIP M stage II sporulation protein P
MLHAACIH_03690 7.2e-53 yqxA S Protein of unknown function (DUF3679)
MLHAACIH_03691 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MLHAACIH_03692 1.7e-215 hemN H Involved in the biosynthesis of porphyrin-containing compound
MLHAACIH_03693 6.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MLHAACIH_03694 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MLHAACIH_03695 0.0 dnaK O Heat shock 70 kDa protein
MLHAACIH_03696 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MLHAACIH_03697 5.4e-175 prmA J Methylates ribosomal protein L11
MLHAACIH_03698 3.6e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MLHAACIH_03699 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
MLHAACIH_03700 7.3e-156 yqeW P COG1283 Na phosphate symporter
MLHAACIH_03701 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MLHAACIH_03702 2.5e-61 yqeY S Yqey-like protein
MLHAACIH_03703 2.3e-227 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
MLHAACIH_03704 4.3e-122 yqfA S UPF0365 protein
MLHAACIH_03705 6e-25 yqfB
MLHAACIH_03706 2.7e-45 yqfC S sporulation protein YqfC
MLHAACIH_03707 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
MLHAACIH_03708 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
MLHAACIH_03710 0.0 yqfF S membrane-associated HD superfamily hydrolase
MLHAACIH_03711 8.8e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MLHAACIH_03712 2.5e-59 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MLHAACIH_03713 3.5e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MLHAACIH_03714 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MLHAACIH_03715 8.4e-19 S YqzL-like protein
MLHAACIH_03716 6.9e-144 recO L Involved in DNA repair and RecF pathway recombination
MLHAACIH_03717 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MLHAACIH_03718 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MLHAACIH_03719 4.5e-112 ccpN K CBS domain
MLHAACIH_03720 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MLHAACIH_03721 4.5e-88 yaiI S Belongs to the UPF0178 family
MLHAACIH_03722 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MLHAACIH_03723 4.4e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MLHAACIH_03724 2.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
MLHAACIH_03725 6.8e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
MLHAACIH_03726 2.6e-208 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MLHAACIH_03727 1.2e-137 yqjF S Uncharacterized conserved protein (COG2071)
MLHAACIH_03728 1.9e-139 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MLHAACIH_03729 4.5e-24 yqzJ
MLHAACIH_03730 3.4e-233 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MLHAACIH_03731 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MLHAACIH_03732 2.8e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MLHAACIH_03733 2.5e-172 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MLHAACIH_03734 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MLHAACIH_03735 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MLHAACIH_03736 3.9e-11 yqfQ S YqfQ-like protein
MLHAACIH_03737 8.5e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MLHAACIH_03738 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MLHAACIH_03739 2.1e-36 yqfT S Protein of unknown function (DUF2624)
MLHAACIH_03740 8.2e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
MLHAACIH_03741 1.9e-77 zur P Belongs to the Fur family
MLHAACIH_03742 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
MLHAACIH_03743 3.7e-61 yqfX S membrane
MLHAACIH_03744 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MLHAACIH_03745 4.4e-46 yqfZ M LysM domain
MLHAACIH_03746 3.9e-131 yqgB S Protein of unknown function (DUF1189)
MLHAACIH_03747 4e-73 yqgC S protein conserved in bacteria
MLHAACIH_03748 3.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
MLHAACIH_03749 1.8e-229 yqgE EGP Major facilitator superfamily
MLHAACIH_03750 0.0 pbpA 3.4.16.4 M penicillin-binding protein
MLHAACIH_03751 2.4e-150 pstS P Phosphate
MLHAACIH_03752 9.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
MLHAACIH_03753 1.3e-157 pstA P Phosphate transport system permease
MLHAACIH_03754 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MLHAACIH_03755 1.4e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MLHAACIH_03756 7.3e-72 yqzC S YceG-like family
MLHAACIH_03757 3.5e-50 yqzD
MLHAACIH_03759 8.1e-199 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
MLHAACIH_03760 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MLHAACIH_03761 2.5e-103 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MLHAACIH_03762 2.5e-09 yqgO
MLHAACIH_03763 3.1e-260 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
MLHAACIH_03764 4.5e-32 yqgQ S Protein conserved in bacteria
MLHAACIH_03765 3.4e-180 glcK 2.7.1.2 G Glucokinase
MLHAACIH_03766 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MLHAACIH_03767 1.6e-221 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
MLHAACIH_03768 8.8e-198 yqgU
MLHAACIH_03769 6.9e-50 yqgV S Thiamine-binding protein
MLHAACIH_03770 8.9e-23 yqgW S Protein of unknown function (DUF2759)
MLHAACIH_03771 2.3e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
MLHAACIH_03772 2e-36 yqgY S Protein of unknown function (DUF2626)
MLHAACIH_03773 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
MLHAACIH_03775 1.5e-147 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MLHAACIH_03776 2.2e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MLHAACIH_03777 6.7e-173 corA P Mg2 transporter protein
MLHAACIH_03778 2.5e-200 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MLHAACIH_03779 1.4e-168 comGB NU COG1459 Type II secretory pathway, component PulF
MLHAACIH_03780 1.2e-46 comGC U Required for transformation and DNA binding
MLHAACIH_03781 4.1e-69 gspH NU protein transport across the cell outer membrane
MLHAACIH_03782 1.3e-57 comGE
MLHAACIH_03783 6e-45 comGF U Putative Competence protein ComGF
MLHAACIH_03784 1.2e-43 S ComG operon protein 7
MLHAACIH_03785 5.2e-26 yqzE S YqzE-like protein
MLHAACIH_03786 2.8e-53 yqzG S Protein of unknown function (DUF3889)
MLHAACIH_03787 4.8e-97 yqxM
MLHAACIH_03788 5.7e-58 sipW 3.4.21.89 U Signal peptidase
MLHAACIH_03789 4.3e-141 tasA S Cell division protein FtsN
MLHAACIH_03790 1e-54 sinR K transcriptional
MLHAACIH_03791 1.2e-24 sinI S Anti-repressor SinI
MLHAACIH_03792 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
MLHAACIH_03793 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
MLHAACIH_03794 1.8e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
MLHAACIH_03795 1.9e-253 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MLHAACIH_03796 4.8e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MLHAACIH_03797 3.3e-62 yqhL P COG0607 Rhodanese-related sulfurtransferase
MLHAACIH_03798 5.7e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MLHAACIH_03799 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MLHAACIH_03800 4e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
MLHAACIH_03801 2.2e-61 yqhP
MLHAACIH_03802 1.5e-172 yqhQ S Protein of unknown function (DUF1385)
MLHAACIH_03803 6.6e-93 yqhR S Conserved membrane protein YqhR
MLHAACIH_03804 1.6e-76 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
MLHAACIH_03805 4.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
MLHAACIH_03806 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MLHAACIH_03807 1.8e-36 yqhV S Protein of unknown function (DUF2619)
MLHAACIH_03808 4e-170 spoIIIAA S stage III sporulation protein AA
MLHAACIH_03809 1.1e-84 spoIIIAB S Stage III sporulation protein
MLHAACIH_03810 7.6e-29 spoIIIAC S stage III sporulation protein AC
MLHAACIH_03811 2.3e-58 spoIIIAD S Stage III sporulation protein AD
MLHAACIH_03812 1.3e-197 spoIIIAE S stage III sporulation protein AE
MLHAACIH_03813 1.2e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
MLHAACIH_03814 2.2e-109 spoIIIAG S stage III sporulation protein AG
MLHAACIH_03815 2.9e-90 spoIIIAH S SpoIIIAH-like protein
MLHAACIH_03816 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MLHAACIH_03817 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MLHAACIH_03818 8.1e-67 yqhY S protein conserved in bacteria
MLHAACIH_03819 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MLHAACIH_03820 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MLHAACIH_03821 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MLHAACIH_03822 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MLHAACIH_03823 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MLHAACIH_03824 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MLHAACIH_03825 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
MLHAACIH_03826 6.6e-78 argR K Regulates arginine biosynthesis genes
MLHAACIH_03827 3.2e-306 recN L May be involved in recombinational repair of damaged DNA
MLHAACIH_03828 2.3e-237 rseP 3.4.21.116 M Stage IV sporulation protein B
MLHAACIH_03829 3.6e-143 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MLHAACIH_03831 4.7e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
MLHAACIH_03833 6e-27
MLHAACIH_03834 7.8e-106 amiC 3.5.1.28 M Cell wall hydrolase autolysin
MLHAACIH_03835 2.3e-128 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MLHAACIH_03836 1.3e-218 mmgA 2.3.1.9 I Belongs to the thiolase family
MLHAACIH_03837 2.6e-155 hbdA 1.1.1.157 I Dehydrogenase
MLHAACIH_03838 6.7e-212 mmgC I acyl-CoA dehydrogenase
MLHAACIH_03839 8.1e-210 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
MLHAACIH_03840 8.2e-276 prpD 4.2.1.79 S 2-methylcitrate dehydratase
MLHAACIH_03841 8.7e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MLHAACIH_03842 4e-34 yqzF S Protein of unknown function (DUF2627)
MLHAACIH_03843 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
MLHAACIH_03844 1e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
MLHAACIH_03845 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
MLHAACIH_03846 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
MLHAACIH_03847 8.3e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MLHAACIH_03848 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MLHAACIH_03849 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MLHAACIH_03850 1.8e-226 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MLHAACIH_03851 4.4e-152 bmrR K helix_turn_helix, mercury resistance
MLHAACIH_03852 3.9e-207 norA EGP Major facilitator Superfamily
MLHAACIH_03853 3.7e-165 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MLHAACIH_03854 6e-76 yqiW S Belongs to the UPF0403 family
MLHAACIH_03855 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
MLHAACIH_03856 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
MLHAACIH_03857 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MLHAACIH_03858 1.2e-172 yqjA S Putative aromatic acid exporter C-terminal domain
MLHAACIH_03859 8.8e-98 yqjB S protein conserved in bacteria
MLHAACIH_03861 1e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
MLHAACIH_03862 6.6e-287 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MLHAACIH_03863 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
MLHAACIH_03864 1.4e-144 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MLHAACIH_03865 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MLHAACIH_03866 0.0 rocB E arginine degradation protein
MLHAACIH_03867 7.3e-68
MLHAACIH_03868 1.6e-106 M Pectate lyase superfamily protein
MLHAACIH_03869 1.9e-65 M Pectate lyase superfamily protein
MLHAACIH_03870 3.7e-119
MLHAACIH_03871 1.6e-293 S Pfam Transposase IS66
MLHAACIH_03872 8.5e-86 S Phage tail protein
MLHAACIH_03873 0.0 S peptidoglycan catabolic process
MLHAACIH_03874 5.4e-46
MLHAACIH_03876 8.3e-190 xerH A Belongs to the 'phage' integrase family
MLHAACIH_03877 1.2e-52
MLHAACIH_03878 5.9e-56
MLHAACIH_03879 3.3e-99 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
MLHAACIH_03880 5.4e-08 S Phage uncharacterised protein (Phage_XkdX)
MLHAACIH_03881 5.9e-11
MLHAACIH_03882 9.5e-18
MLHAACIH_03883 1.2e-45
MLHAACIH_03886 3.2e-59
MLHAACIH_03887 2.3e-72
MLHAACIH_03888 1.7e-77
MLHAACIH_03889 6.4e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MLHAACIH_03890 1.6e-177 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
MLHAACIH_03891 1.7e-142 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
MLHAACIH_03892 2.1e-260 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
MLHAACIH_03893 3.5e-177 coaA 2.7.1.33 F Pantothenic acid kinase
MLHAACIH_03894 8.8e-71 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLHAACIH_03896 5.8e-225 yqjV G Major Facilitator Superfamily
MLHAACIH_03898 2e-238 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MLHAACIH_03899 1.7e-49 S YolD-like protein
MLHAACIH_03900 8.1e-87 yqjY K acetyltransferase
MLHAACIH_03901 2e-58 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
MLHAACIH_03902 2.2e-193 yqkA K GrpB protein
MLHAACIH_03903 2.8e-54 yqkB S Belongs to the HesB IscA family
MLHAACIH_03904 9.4e-39 yqkC S Protein of unknown function (DUF2552)
MLHAACIH_03905 1.2e-171 yqkD S COG1073 Hydrolases of the alpha beta superfamily
MLHAACIH_03906 9.1e-12 yqkE S Protein of unknown function (DUF3886)
MLHAACIH_03907 6.3e-168 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
MLHAACIH_03909 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
MLHAACIH_03910 3.1e-220 yqxK 3.6.4.12 L DNA helicase
MLHAACIH_03911 1.3e-57 ansR K Transcriptional regulator
MLHAACIH_03912 1.8e-184 ansA 3.5.1.1 EJ L-asparaginase
MLHAACIH_03913 1.9e-267 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
MLHAACIH_03914 9.1e-235 mleN C Na H antiporter
MLHAACIH_03915 5.5e-242 mleA 1.1.1.38 C malic enzyme
MLHAACIH_03916 6.5e-31 yqkK
MLHAACIH_03917 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MLHAACIH_03918 2.4e-80 fur P Belongs to the Fur family
MLHAACIH_03919 1.4e-36 S Protein of unknown function (DUF4227)
MLHAACIH_03920 2.6e-166 xerD L recombinase XerD
MLHAACIH_03921 6.7e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
MLHAACIH_03922 3.8e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MLHAACIH_03923 2.4e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
MLHAACIH_03924 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
MLHAACIH_03925 5.1e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MLHAACIH_03926 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLHAACIH_03927 9.6e-112 spoVAA S Stage V sporulation protein AA
MLHAACIH_03928 1e-67 spoVAB S Stage V sporulation protein AB
MLHAACIH_03929 2.3e-78 spoVAC S stage V sporulation protein AC
MLHAACIH_03930 2.9e-190 spoVAD I Stage V sporulation protein AD
MLHAACIH_03931 2.2e-57 spoVAEB S stage V sporulation protein
MLHAACIH_03932 1.4e-110 spoVAEA S stage V sporulation protein
MLHAACIH_03933 1.7e-271 spoVAF EG Stage V sporulation protein AF
MLHAACIH_03934 8.8e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MLHAACIH_03935 1.3e-149 ypuA S Secreted protein
MLHAACIH_03936 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MLHAACIH_03938 4.7e-09 eaeH M Domain of Unknown Function (DUF1259)
MLHAACIH_03940 1.4e-08 S SNARE associated Golgi protein
MLHAACIH_03941 6.6e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
MLHAACIH_03943 8e-94 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MLHAACIH_03944 7.8e-55 ypuD
MLHAACIH_03945 4.2e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MLHAACIH_03946 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
MLHAACIH_03947 1.9e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MLHAACIH_03948 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MLHAACIH_03949 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLHAACIH_03950 3.9e-90 ypuF S Domain of unknown function (DUF309)
MLHAACIH_03951 6.4e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MLHAACIH_03952 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MLHAACIH_03953 4e-98 ypuI S Protein of unknown function (DUF3907)
MLHAACIH_03954 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
MLHAACIH_03955 5.9e-103 spmA S Spore maturation protein
MLHAACIH_03956 1.9e-87 spmB S Spore maturation protein
MLHAACIH_03957 2e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MLHAACIH_03958 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MLHAACIH_03959 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
MLHAACIH_03960 4.4e-214 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MLHAACIH_03961 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLHAACIH_03962 0.0 resE 2.7.13.3 T Histidine kinase
MLHAACIH_03963 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
MLHAACIH_03964 3.1e-198 rsiX
MLHAACIH_03965 6.5e-134 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MLHAACIH_03966 7.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLHAACIH_03967 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MLHAACIH_03968 4.7e-41 fer C Ferredoxin
MLHAACIH_03969 1.9e-200 ypbB 5.1.3.1 S protein conserved in bacteria
MLHAACIH_03970 6e-285 recQ 3.6.4.12 L DNA helicase
MLHAACIH_03971 6.9e-99 ypbD S metal-dependent membrane protease
MLHAACIH_03972 5.5e-74 ypbE M Lysin motif
MLHAACIH_03973 2.8e-81 ypbF S Protein of unknown function (DUF2663)
MLHAACIH_03974 3.4e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
MLHAACIH_03975 9.1e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MLHAACIH_03976 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
MLHAACIH_03977 2.1e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
MLHAACIH_03978 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
MLHAACIH_03979 5.7e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
MLHAACIH_03980 9.3e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
MLHAACIH_03981 5.2e-108 ypfA M Flagellar protein YcgR
MLHAACIH_03982 1.8e-23 S Family of unknown function (DUF5359)
MLHAACIH_03983 2.8e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MLHAACIH_03984 3.1e-204 rpsA 1.17.7.4 J Ribosomal protein S1
MLHAACIH_03985 4.2e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MLHAACIH_03986 1e-07 S YpzI-like protein
MLHAACIH_03987 1.9e-101 yphA
MLHAACIH_03988 2.5e-161 seaA S YIEGIA protein
MLHAACIH_03989 6e-28 ypzH
MLHAACIH_03990 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MLHAACIH_03991 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MLHAACIH_03992 1.6e-18 yphE S Protein of unknown function (DUF2768)
MLHAACIH_03993 6e-137 yphF
MLHAACIH_03994 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MLHAACIH_03995 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MLHAACIH_03996 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
MLHAACIH_03997 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MLHAACIH_03998 2.8e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
MLHAACIH_03999 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MLHAACIH_04000 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MLHAACIH_04001 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MLHAACIH_04002 1.1e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
MLHAACIH_04003 1.2e-216 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MLHAACIH_04004 6.5e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MLHAACIH_04005 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
MLHAACIH_04006 6.6e-295 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MLHAACIH_04007 1.2e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MLHAACIH_04008 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
MLHAACIH_04009 1e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
MLHAACIH_04010 1.5e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MLHAACIH_04011 9.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MLHAACIH_04012 4.2e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MLHAACIH_04013 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
MLHAACIH_04014 3.4e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MLHAACIH_04015 4.1e-234 S COG0457 FOG TPR repeat
MLHAACIH_04016 2.8e-99 ypiB S Belongs to the UPF0302 family
MLHAACIH_04017 1e-75 ypiF S Protein of unknown function (DUF2487)
MLHAACIH_04018 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
MLHAACIH_04019 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
MLHAACIH_04020 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
MLHAACIH_04021 1.1e-99 ypjA S membrane
MLHAACIH_04022 6.1e-143 ypjB S sporulation protein
MLHAACIH_04023 1.8e-156 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
MLHAACIH_04024 2.6e-55 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
MLHAACIH_04025 7e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MLHAACIH_04026 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
MLHAACIH_04027 7.6e-129 bshB1 S proteins, LmbE homologs
MLHAACIH_04028 2e-208 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
MLHAACIH_04029 5e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MLHAACIH_04030 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MLHAACIH_04031 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MLHAACIH_04032 6.8e-156 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MLHAACIH_04033 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MLHAACIH_04034 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MLHAACIH_04035 6.7e-23 ypmA S Protein of unknown function (DUF4264)
MLHAACIH_04036 3.4e-80 ypmB S protein conserved in bacteria
MLHAACIH_04037 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
MLHAACIH_04038 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
MLHAACIH_04039 5.7e-129 dnaD L DNA replication protein DnaD
MLHAACIH_04040 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MLHAACIH_04041 4.7e-93 ypoC
MLHAACIH_04042 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
MLHAACIH_04043 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MLHAACIH_04044 2.6e-188 yppC S Protein of unknown function (DUF2515)
MLHAACIH_04047 5.7e-11 yppE S Bacterial domain of unknown function (DUF1798)
MLHAACIH_04049 1.2e-48 yppG S YppG-like protein
MLHAACIH_04050 2.5e-71 hspX O Belongs to the small heat shock protein (HSP20) family
MLHAACIH_04051 1.6e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
MLHAACIH_04052 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MLHAACIH_04053 1.9e-236 yprB L RNase_H superfamily
MLHAACIH_04054 5.3e-90 ypsA S Belongs to the UPF0398 family
MLHAACIH_04055 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MLHAACIH_04056 9.2e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MLHAACIH_04058 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
MLHAACIH_04059 1.3e-129 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLHAACIH_04060 4.1e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MLHAACIH_04061 3.3e-186 ptxS K transcriptional
MLHAACIH_04062 1.1e-186 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
MLHAACIH_04063 1.3e-102 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
MLHAACIH_04064 1.9e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
MLHAACIH_04065 9.3e-294 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MLHAACIH_04066 2.6e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MLHAACIH_04067 2.9e-227 pbuX F xanthine
MLHAACIH_04068 6.3e-207 bcsA Q Naringenin-chalcone synthase
MLHAACIH_04069 6.7e-87 ypbQ S protein conserved in bacteria
MLHAACIH_04071 0.0 ypbR S Dynamin family
MLHAACIH_04072 2.9e-38 ypbS S Protein of unknown function (DUF2533)
MLHAACIH_04073 2e-07
MLHAACIH_04074 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
MLHAACIH_04076 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
MLHAACIH_04077 1.3e-105 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MLHAACIH_04078 1.7e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
MLHAACIH_04079 3e-29 ypeQ S Zinc-finger
MLHAACIH_04080 8.1e-31 S Protein of unknown function (DUF2564)
MLHAACIH_04081 3.8e-16 degR
MLHAACIH_04082 1e-30 cspD K Cold-shock protein
MLHAACIH_04083 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
MLHAACIH_04084 1.2e-174 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MLHAACIH_04085 2.2e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
MLHAACIH_04086 6.7e-58 ypgQ S phosphohydrolase
MLHAACIH_04087 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
MLHAACIH_04088 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
MLHAACIH_04089 1.7e-75 yphP S Belongs to the UPF0403 family
MLHAACIH_04090 1.9e-141 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
MLHAACIH_04091 5.5e-104 ypjP S YpjP-like protein
MLHAACIH_04092 3.6e-91 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
MLHAACIH_04093 4.8e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MLHAACIH_04094 4.8e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MLHAACIH_04095 1.4e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MLHAACIH_04096 4.2e-110 hlyIII S protein, Hemolysin III
MLHAACIH_04097 6.8e-184 pspF K Transcriptional regulator
MLHAACIH_04098 9.7e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MLHAACIH_04099 3.1e-40 ypmP S Protein of unknown function (DUF2535)
MLHAACIH_04100 1.3e-105 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MLHAACIH_04101 1.1e-136 ypmR E GDSL-like Lipase/Acylhydrolase
MLHAACIH_04102 1.1e-98 ypmS S protein conserved in bacteria
MLHAACIH_04103 1.2e-28 ypmT S Uncharacterized ympT
MLHAACIH_04104 1.9e-221 mepA V MATE efflux family protein
MLHAACIH_04105 1.6e-70 ypoP K transcriptional
MLHAACIH_04106 3.9e-101 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MLHAACIH_04107 2.9e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MLHAACIH_04108 1.4e-96 4.2.1.115 GM Polysaccharide biosynthesis protein
MLHAACIH_04109 4.9e-240 yokA L Recombinase
MLHAACIH_04111 7.1e-65 S SMI1 / KNR4 family
MLHAACIH_04112 2.6e-54 S DNase/tRNase domain of colicin-like bacteriocin
MLHAACIH_04113 1.5e-105 yokF 3.1.31.1 L RNA catabolic process
MLHAACIH_04114 4.6e-36
MLHAACIH_04115 1.5e-65 G SMI1-KNR4 cell-wall
MLHAACIH_04116 1.7e-08
MLHAACIH_04119 1.2e-95
MLHAACIH_04124 2.1e-49 FG Scavenger mRNA decapping enzyme C-term binding
MLHAACIH_04125 3.8e-36
MLHAACIH_04126 7.7e-10
MLHAACIH_04127 5.8e-32 yoaF
MLHAACIH_04129 8.6e-106
MLHAACIH_04134 2.6e-197 L Belongs to the 'phage' integrase family
MLHAACIH_04135 1.6e-260 S DNA-sulfur modification-associated
MLHAACIH_04136 2.1e-177
MLHAACIH_04137 1.1e-33 K Transcriptional regulator
MLHAACIH_04141 3.4e-22
MLHAACIH_04142 1.9e-53 S dUTPase
MLHAACIH_04143 2.9e-16 3.1.3.16, 3.1.4.37 T AAA domain
MLHAACIH_04147 5.5e-47 S Protein of unknown function (DUF1273)
MLHAACIH_04148 2.4e-43 S Protein of unknown function (DUF1273)
MLHAACIH_04155 3.2e-147 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
MLHAACIH_04157 2.2e-154
MLHAACIH_04164 1.2e-11 S AAA domain
MLHAACIH_04165 1.8e-09
MLHAACIH_04166 2.5e-145 dnaG 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MLHAACIH_04167 9.5e-59 L DNA primase activity
MLHAACIH_04168 9.6e-122 recJ L Single-stranded-DNA-specific exonuclease RecJ
MLHAACIH_04169 6.4e-20 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MLHAACIH_04170 6.1e-110 DR0488 S protein conserved in bacteria
MLHAACIH_04175 4.1e-81 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
MLHAACIH_04177 5e-10 L transposase activity
MLHAACIH_04178 2.6e-163 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
MLHAACIH_04189 7.5e-77 yhdJ 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
MLHAACIH_04193 2.8e-64 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
MLHAACIH_04194 3.5e-113 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MLHAACIH_04195 1.7e-48 S HNH endonuclease
MLHAACIH_04196 2.3e-226 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MLHAACIH_04197 2.2e-54 S Protein of unknown function (DUF1140)
MLHAACIH_04198 1.7e-100 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MLHAACIH_04201 3.6e-30 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MLHAACIH_04202 1.9e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
MLHAACIH_04207 6.8e-161 S Thymidylate synthase
MLHAACIH_04208 5.4e-31 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MLHAACIH_04210 1.2e-35
MLHAACIH_04212 4.7e-29 sspB S spore protein
MLHAACIH_04216 8.4e-11 K Cro/C1-type HTH DNA-binding domain
MLHAACIH_04217 2.3e-102 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MLHAACIH_04219 1.1e-62 4.2.1.115 GM Polysaccharide biosynthesis protein
MLHAACIH_04220 6.4e-210 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
MLHAACIH_04221 1.4e-186 cgeB S Spore maturation protein
MLHAACIH_04222 4.8e-64 cgeA
MLHAACIH_04223 5.9e-38 cgeC
MLHAACIH_04224 8e-254 cgeD M maturation of the outermost layer of the spore
MLHAACIH_04225 9.2e-144 yiiD K acetyltransferase
MLHAACIH_04227 2.1e-238 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MLHAACIH_04228 2.4e-09 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MLHAACIH_04229 5.2e-116 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MLHAACIH_04230 1.2e-257 yodQ 3.5.1.16 E Acetylornithine deacetylase
MLHAACIH_04231 8.8e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
MLHAACIH_04232 1.4e-275 kamA 5.4.3.2 E lysine 2,3-aminomutase
MLHAACIH_04233 2.9e-47 yokU S YokU-like protein, putative antitoxin
MLHAACIH_04234 3.1e-36 yozE S Belongs to the UPF0346 family
MLHAACIH_04235 6e-123 yodN
MLHAACIH_04237 2.8e-24 yozD S YozD-like protein
MLHAACIH_04238 6.6e-105 yodM 3.6.1.27 I Acid phosphatase homologues
MLHAACIH_04239 7.9e-54 yodL S YodL-like
MLHAACIH_04240 5.3e-09
MLHAACIH_04241 4.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
MLHAACIH_04242 2.1e-138 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
MLHAACIH_04243 2e-23 yodI
MLHAACIH_04244 2.4e-127 yodH Q Methyltransferase
MLHAACIH_04245 9.7e-253 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
MLHAACIH_04246 1.2e-269 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLHAACIH_04247 6.2e-28 S Protein of unknown function (DUF3311)
MLHAACIH_04248 5.8e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
MLHAACIH_04249 2.7e-111 mhqD S Carboxylesterase
MLHAACIH_04250 4.6e-09 mhqD S Carboxylesterase
MLHAACIH_04251 4.8e-108 yodC C nitroreductase
MLHAACIH_04252 4.4e-55 yodB K transcriptional
MLHAACIH_04253 1.4e-63 yodA S tautomerase
MLHAACIH_04254 1.2e-204 gntP EG COG2610 H gluconate symporter and related permeases
MLHAACIH_04255 2e-09
MLHAACIH_04256 1.5e-64 yozR S COG0071 Molecular chaperone (small heat shock protein)
MLHAACIH_04257 1.2e-160 rarD S -transporter
MLHAACIH_04258 1.5e-43
MLHAACIH_04259 2.2e-60 yojF S Protein of unknown function (DUF1806)
MLHAACIH_04260 2.1e-125 yojG S deacetylase
MLHAACIH_04261 1.6e-149 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MLHAACIH_04262 2.2e-241 norM V Multidrug efflux pump
MLHAACIH_04264 5.8e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MLHAACIH_04265 1e-229 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
MLHAACIH_04266 6.2e-195 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MLHAACIH_04267 5.6e-109 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MLHAACIH_04268 2.5e-161 yojN S ATPase family associated with various cellular activities (AAA)
MLHAACIH_04269 0.0 yojO P Von Willebrand factor
MLHAACIH_04270 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MLHAACIH_04271 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MLHAACIH_04272 8.6e-168 yocS S -transporter
MLHAACIH_04273 1.3e-230 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MLHAACIH_04274 2.3e-164 sodA 1.15.1.1 P Superoxide dismutase
MLHAACIH_04275 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
MLHAACIH_04276 4.4e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
MLHAACIH_04277 2.7e-31 yozC
MLHAACIH_04278 4.2e-56 yozO S Bacterial PH domain
MLHAACIH_04279 1.9e-36 yocN
MLHAACIH_04280 1.1e-40 yozN
MLHAACIH_04281 5.9e-85 yocM O Belongs to the small heat shock protein (HSP20) family
MLHAACIH_04282 1.7e-29
MLHAACIH_04283 8.4e-54 yocL
MLHAACIH_04284 3.3e-83 dksA T general stress protein
MLHAACIH_04285 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MLHAACIH_04286 0.0 recQ 3.6.4.12 L DNA helicase
MLHAACIH_04287 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
MLHAACIH_04288 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLHAACIH_04289 1.7e-196 desK 2.7.13.3 T Histidine kinase
MLHAACIH_04290 5.3e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
MLHAACIH_04291 1.8e-184 yocD 3.4.17.13 V peptidase S66
MLHAACIH_04292 1.5e-91 yocC
MLHAACIH_04293 5.1e-142
MLHAACIH_04294 1.5e-92 yozB S membrane
MLHAACIH_04296 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MLHAACIH_04297 1e-51 czrA K transcriptional
MLHAACIH_04298 2.6e-92 yobW
MLHAACIH_04299 2.7e-174 yobV K WYL domain
MLHAACIH_04300 3.1e-86 yobU K Bacterial transcription activator, effector binding domain
MLHAACIH_04301 2.1e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
MLHAACIH_04302 2.8e-97 yobS K Transcriptional regulator
MLHAACIH_04303 8.5e-139 yobR 2.3.1.1 J FR47-like protein
MLHAACIH_04304 1.1e-135 yobQ K helix_turn_helix, arabinose operon control protein
MLHAACIH_04305 9.3e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
MLHAACIH_04306 2.4e-221 yobO M Pectate lyase superfamily protein
MLHAACIH_04307 1e-198 yobO M Pectate lyase superfamily protein
MLHAACIH_04308 1.1e-275 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
MLHAACIH_04309 1.1e-101 yokH G SMI1 / KNR4 family
MLHAACIH_04310 5e-182 UW nuclease activity
MLHAACIH_04311 1.9e-94 yokJ S SMI1 / KNR4 family (SUKH-1)
MLHAACIH_04312 2.2e-80 yokK S SMI1 / KNR4 family
MLHAACIH_04313 1.4e-107 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
MLHAACIH_04314 1.6e-189 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MLHAACIH_04315 6.7e-86 S SMI1-KNR4 cell-wall
MLHAACIH_04316 2.3e-78 S SMI1-KNR4 cell-wall
MLHAACIH_04317 1.2e-94 yokK S SMI1 / KNR4 family
MLHAACIH_04318 1.3e-96 J Acetyltransferase (GNAT) domain
MLHAACIH_04320 4e-09 S Domain of unknown function (DUF4879)
MLHAACIH_04322 1.3e-40
MLHAACIH_04323 4.6e-52 S YolD-like protein
MLHAACIH_04324 1.9e-236 S impB/mucB/samB family C-terminal domain
MLHAACIH_04327 0.0 V Peptidase C39 family
MLHAACIH_04328 1.2e-70 CO cell redox homeostasis
MLHAACIH_04329 4.1e-242 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MLHAACIH_04330 3.4e-74 O protein disulfide oxidoreductase activity
MLHAACIH_04331 5.5e-40 S SPP1 phage holin
MLHAACIH_04332 4.4e-32 bhlA S BhlA holin family
MLHAACIH_04333 1.6e-186 3.5.1.28 M Ami_2
MLHAACIH_04334 2.4e-87
MLHAACIH_04335 2e-22 L Transposase
MLHAACIH_04336 2.3e-87 L Tn3 transposase DDE domain
MLHAACIH_04337 1.5e-75
MLHAACIH_04338 1.5e-194 L Replication protein
MLHAACIH_04340 1e-21
MLHAACIH_04341 3.4e-224 pre D plasmid recombination enzyme
MLHAACIH_04342 3e-68 K Transcriptional regulator
MLHAACIH_04344 3.5e-42 S Putative amidase domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)