ORF_ID e_value Gene_name EC_number CAZy COGs Description
HAFJMHLM_00001 2.3e-99 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HAFJMHLM_00002 2.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HAFJMHLM_00003 4.3e-242 dnaB L Replication initiation and membrane attachment
HAFJMHLM_00004 3.5e-163 dnaI L Primosomal protein DnaI
HAFJMHLM_00005 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HAFJMHLM_00006 2.3e-32
HAFJMHLM_00007 9.3e-272 S Archaea bacterial proteins of unknown function
HAFJMHLM_00008 2.6e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HAFJMHLM_00009 1.8e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HAFJMHLM_00010 2.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HAFJMHLM_00011 1.1e-211 yqeH S Ribosome biogenesis GTPase YqeH
HAFJMHLM_00012 1.5e-112 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HAFJMHLM_00013 7.5e-106 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HAFJMHLM_00014 4.5e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HAFJMHLM_00015 1.2e-211 ylbM S Belongs to the UPF0348 family
HAFJMHLM_00016 3.5e-100 yceD S Uncharacterized ACR, COG1399
HAFJMHLM_00017 2.7e-126 K response regulator
HAFJMHLM_00018 3.2e-284 arlS 2.7.13.3 T Histidine kinase
HAFJMHLM_00019 3.5e-153 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HAFJMHLM_00020 4.2e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HAFJMHLM_00021 5.5e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HAFJMHLM_00022 1.4e-59 yodB K Transcriptional regulator, HxlR family
HAFJMHLM_00023 1.3e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HAFJMHLM_00024 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HAFJMHLM_00025 4.5e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HAFJMHLM_00026 0.0 S membrane
HAFJMHLM_00027 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HAFJMHLM_00028 7.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HAFJMHLM_00029 1.2e-100 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HAFJMHLM_00030 2.6e-115 gluP 3.4.21.105 S Rhomboid family
HAFJMHLM_00031 5.6e-33 yqgQ S Bacterial protein of unknown function (DUF910)
HAFJMHLM_00032 2.6e-70 yqhL P Rhodanese-like protein
HAFJMHLM_00033 4.3e-164 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HAFJMHLM_00034 1e-216 ynbB 4.4.1.1 P aluminum resistance
HAFJMHLM_00035 1.7e-254 glnA 6.3.1.2 E glutamine synthetase
HAFJMHLM_00036 1.2e-209 EGP Major facilitator Superfamily
HAFJMHLM_00037 3.8e-55 S Domain of unknown function DUF1828
HAFJMHLM_00038 1.7e-268 E amino acid
HAFJMHLM_00039 9.9e-152 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, C-terminal domain
HAFJMHLM_00040 6.4e-213 yceI EGP Major facilitator Superfamily
HAFJMHLM_00041 5.4e-90 L Transposase and inactivated derivatives, IS30 family
HAFJMHLM_00042 8.7e-50 L Winged helix-turn helix
HAFJMHLM_00043 2.3e-168 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HAFJMHLM_00044 7e-167 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HAFJMHLM_00045 1.6e-124 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HAFJMHLM_00047 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HAFJMHLM_00049 0.0 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HAFJMHLM_00050 1.1e-290 S SH3-like domain
HAFJMHLM_00051 5.1e-35 XK27_05520 S Uncharacterized protein conserved in bacteria (DUF2087)
HAFJMHLM_00052 4.6e-208 L COG3547 Transposase and inactivated derivatives
HAFJMHLM_00053 4.4e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HAFJMHLM_00054 2.8e-210 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HAFJMHLM_00055 2.2e-251 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HAFJMHLM_00056 8e-134 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HAFJMHLM_00057 2e-36 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HAFJMHLM_00058 7.5e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HAFJMHLM_00059 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HAFJMHLM_00060 7.8e-277 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HAFJMHLM_00061 5.1e-190 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HAFJMHLM_00062 7.4e-106 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HAFJMHLM_00063 8.3e-290 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HAFJMHLM_00064 9.4e-239 purD 6.3.4.13 F Belongs to the GARS family
HAFJMHLM_00065 1e-44 livJ E Receptor family ligand binding region
HAFJMHLM_00066 4.6e-23 livM E Branched-chain amino acid transport system / permease component
HAFJMHLM_00067 9.5e-80 livF E ABC transporter
HAFJMHLM_00068 5.4e-55 metC1 4.4.1.8 E cystathionine
HAFJMHLM_00069 5.6e-64 arsC 1.20.4.1 P Belongs to the ArsC family
HAFJMHLM_00070 9.9e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HAFJMHLM_00071 1.6e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HAFJMHLM_00072 1.4e-193 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HAFJMHLM_00073 2.9e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HAFJMHLM_00074 1.3e-70 yqhY S Asp23 family, cell envelope-related function
HAFJMHLM_00075 4.3e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HAFJMHLM_00076 2.6e-152 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HAFJMHLM_00077 9.9e-210 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HAFJMHLM_00078 1.7e-32 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HAFJMHLM_00079 8.6e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HAFJMHLM_00080 3.6e-151 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HAFJMHLM_00081 1.3e-299 recN L May be involved in recombinational repair of damaged DNA
HAFJMHLM_00082 1.7e-98 oppA E ABC transporter, substratebinding protein
HAFJMHLM_00083 1.6e-46
HAFJMHLM_00084 7.6e-109 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HAFJMHLM_00085 2.4e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HAFJMHLM_00086 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HAFJMHLM_00087 6.3e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HAFJMHLM_00088 5.5e-242 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HAFJMHLM_00089 1.4e-136 stp 3.1.3.16 T phosphatase
HAFJMHLM_00090 0.0 KLT serine threonine protein kinase
HAFJMHLM_00091 1e-162 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HAFJMHLM_00092 5.8e-126 thiN 2.7.6.2 H thiamine pyrophosphokinase
HAFJMHLM_00095 8.5e-282 V ABC transporter transmembrane region
HAFJMHLM_00096 1.6e-25 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HAFJMHLM_00097 8.8e-57 asp S Asp23 family, cell envelope-related function
HAFJMHLM_00098 1e-272 yloV S DAK2 domain fusion protein YloV
HAFJMHLM_00099 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HAFJMHLM_00100 1.7e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HAFJMHLM_00101 5.7e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HAFJMHLM_00102 1.1e-189 oppD P Belongs to the ABC transporter superfamily
HAFJMHLM_00103 5.9e-177 oppF P Belongs to the ABC transporter superfamily
HAFJMHLM_00104 8e-174 oppB P ABC transporter permease
HAFJMHLM_00105 1.8e-146 oppC P Binding-protein-dependent transport system inner membrane component
HAFJMHLM_00106 3.5e-308 oppA1 E ABC transporter substrate-binding protein
HAFJMHLM_00107 0.0 oppA E ABC transporter substrate-binding protein
HAFJMHLM_00108 1.6e-126 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HAFJMHLM_00109 0.0 smc D Required for chromosome condensation and partitioning
HAFJMHLM_00110 3.8e-155 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HAFJMHLM_00111 6.2e-42 pipD E Dipeptidase
HAFJMHLM_00112 1.8e-34 pipD E Dipeptidase
HAFJMHLM_00113 9.5e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HAFJMHLM_00114 2.6e-245 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HAFJMHLM_00115 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HAFJMHLM_00116 4.5e-91 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HAFJMHLM_00117 1.4e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HAFJMHLM_00119 1.8e-44 snf 2.7.11.1 KL domain protein
HAFJMHLM_00120 2.1e-55 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HAFJMHLM_00121 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
HAFJMHLM_00122 0.0 S TerB-C domain
HAFJMHLM_00123 7e-245 P P-loop Domain of unknown function (DUF2791)
HAFJMHLM_00124 0.0 lhr L DEAD DEAH box helicase
HAFJMHLM_00125 2.3e-93
HAFJMHLM_00126 8.6e-151 glnH ET ABC transporter substrate-binding protein
HAFJMHLM_00127 1e-143 glcU U ribose uptake protein RbsU
HAFJMHLM_00128 3.5e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HAFJMHLM_00129 3.4e-33 ynzC S UPF0291 protein
HAFJMHLM_00130 3e-31 yneF S Uncharacterised protein family (UPF0154)
HAFJMHLM_00131 0.0 mdlA V ABC transporter
HAFJMHLM_00132 0.0 mdlB V ABC transporter
HAFJMHLM_00133 2.5e-54 L Transposase DDE domain
HAFJMHLM_00134 7.7e-124 S Oxidoreductase
HAFJMHLM_00135 3e-128
HAFJMHLM_00136 1.1e-129 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HAFJMHLM_00137 1.9e-202 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HAFJMHLM_00138 2.7e-106 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HAFJMHLM_00139 0.0 XK27_08315 M Sulfatase
HAFJMHLM_00140 4.7e-09 S Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
HAFJMHLM_00141 3.2e-18 S Acyltransferase family
HAFJMHLM_00143 6.5e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HAFJMHLM_00145 3.8e-227 L DDE superfamily endonuclease
HAFJMHLM_00146 1.2e-22 cspC K Probable zinc-ribbon domain
HAFJMHLM_00147 4.2e-17 L DDE superfamily endonuclease
HAFJMHLM_00148 3.8e-119 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HAFJMHLM_00149 1.1e-162 oppA E ABC transporter, substratebinding protein
HAFJMHLM_00150 2.7e-283 oppA E ABC transporter, substratebinding protein
HAFJMHLM_00151 1.1e-84 oppA E ABC transporter, substratebinding protein
HAFJMHLM_00152 5.5e-70 oppA E ABC transporter, substratebinding protein
HAFJMHLM_00153 1.3e-17 oppA E ABC transporter, substratebinding protein
HAFJMHLM_00154 7.3e-300 oppA E ABC transporter
HAFJMHLM_00155 5.9e-142 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HAFJMHLM_00156 6e-167 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HAFJMHLM_00157 5.6e-197 oppD P Belongs to the ABC transporter superfamily
HAFJMHLM_00158 2.4e-178 oppF P Belongs to the ABC transporter superfamily
HAFJMHLM_00159 1e-251 pepC 3.4.22.40 E aminopeptidase
HAFJMHLM_00160 3.9e-256 pepC 3.4.22.40 E Papain family cysteine protease
HAFJMHLM_00161 6.1e-57 hsp O Belongs to the small heat shock protein (HSP20) family
HAFJMHLM_00162 4.7e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HAFJMHLM_00163 4.4e-244 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HAFJMHLM_00164 5.9e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HAFJMHLM_00165 5.8e-32 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HAFJMHLM_00166 1.1e-114 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HAFJMHLM_00167 5.3e-221 pbuX F xanthine permease
HAFJMHLM_00168 5e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HAFJMHLM_00169 4e-204 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HAFJMHLM_00170 4.4e-299 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HAFJMHLM_00171 9.7e-66 V ABC-type multidrug transport system, ATPase and permease components
HAFJMHLM_00173 1.7e-129 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HAFJMHLM_00174 5.2e-128 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HAFJMHLM_00175 3.4e-101 tcyB E ABC transporter
HAFJMHLM_00177 1.9e-130 2.4.2.3 F Phosphorylase superfamily
HAFJMHLM_00178 8.5e-248 yxbA 6.3.1.12 S ATP-grasp enzyme
HAFJMHLM_00179 2.4e-162 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HAFJMHLM_00180 1.2e-35 mmuP E amino acid
HAFJMHLM_00181 1.1e-28 mmuP E amino acid
HAFJMHLM_00182 2.8e-171 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HAFJMHLM_00183 2.6e-69 ywhH S Aminoacyl-tRNA editing domain
HAFJMHLM_00184 2.2e-73 K DNA-binding transcription factor activity
HAFJMHLM_00185 1.8e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
HAFJMHLM_00186 5.9e-93 S Sucrose-6F-phosphate phosphohydrolase
HAFJMHLM_00187 2.2e-79 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HAFJMHLM_00188 1.9e-267 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HAFJMHLM_00189 1.2e-105 pncA Q Isochorismatase family
HAFJMHLM_00190 1.2e-109
HAFJMHLM_00191 1.9e-40 L Membrane
HAFJMHLM_00192 3.3e-135 2.7.7.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
HAFJMHLM_00193 2.3e-39 S Enterocin A Immunity
HAFJMHLM_00195 6.1e-100 E peptidase
HAFJMHLM_00196 3.6e-135 V ABC-2 type transporter
HAFJMHLM_00197 1.3e-123 V ATPases associated with a variety of cellular activities
HAFJMHLM_00198 1.4e-116
HAFJMHLM_00200 3.3e-194 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HAFJMHLM_00201 8.9e-89 comEB 3.5.4.12 F MafB19-like deaminase
HAFJMHLM_00202 3.4e-101 S TPM domain
HAFJMHLM_00203 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HAFJMHLM_00204 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HAFJMHLM_00205 4.7e-148 tatD L hydrolase, TatD family
HAFJMHLM_00206 1.2e-95 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HAFJMHLM_00207 7.5e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HAFJMHLM_00208 1.1e-37 veg S Biofilm formation stimulator VEG
HAFJMHLM_00209 5e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HAFJMHLM_00210 3.4e-83 guaB2 L Resolvase, N terminal domain
HAFJMHLM_00211 4.1e-50
HAFJMHLM_00212 4.4e-92
HAFJMHLM_00213 1e-114
HAFJMHLM_00214 2.2e-104
HAFJMHLM_00215 5e-108 V AAA domain, putative AbiEii toxin, Type IV TA system
HAFJMHLM_00216 3.9e-87
HAFJMHLM_00217 3.2e-55
HAFJMHLM_00218 6.8e-139
HAFJMHLM_00219 3.5e-67
HAFJMHLM_00220 4e-267 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HAFJMHLM_00221 6.7e-290 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HAFJMHLM_00222 1.8e-63 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HAFJMHLM_00223 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HAFJMHLM_00224 1.1e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HAFJMHLM_00225 1.5e-142 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HAFJMHLM_00226 3.5e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HAFJMHLM_00227 3.2e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HAFJMHLM_00228 7.5e-242 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HAFJMHLM_00229 5e-199 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HAFJMHLM_00230 2.2e-37 yaaA S S4 domain protein YaaA
HAFJMHLM_00231 7.3e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HAFJMHLM_00232 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HAFJMHLM_00233 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HAFJMHLM_00234 8.8e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
HAFJMHLM_00235 1.5e-74 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HAFJMHLM_00236 5.6e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HAFJMHLM_00237 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HAFJMHLM_00238 7.6e-74 rplI J Binds to the 23S rRNA
HAFJMHLM_00239 4.9e-249 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HAFJMHLM_00240 1.9e-225 MA20_36090 S Protein of unknown function (DUF2974)
HAFJMHLM_00243 1.8e-139 K LytTr DNA-binding domain
HAFJMHLM_00244 1.2e-191 2.7.13.3 T GHKL domain
HAFJMHLM_00246 5.4e-25
HAFJMHLM_00247 5.6e-303 msbA2 3.6.3.44 V ABC transporter
HAFJMHLM_00248 0.0 KLT Protein kinase domain
HAFJMHLM_00249 1e-20
HAFJMHLM_00251 7.6e-112 ybbL S ABC transporter, ATP-binding protein
HAFJMHLM_00252 4.8e-129 ybbM S Uncharacterised protein family (UPF0014)
HAFJMHLM_00253 6.5e-11
HAFJMHLM_00254 8e-103 L Transposase
HAFJMHLM_00255 2.1e-126 cbiO P ABC transporter
HAFJMHLM_00256 5e-179 nikMN P PDGLE domain
HAFJMHLM_00257 5.3e-117 K Crp-like helix-turn-helix domain
HAFJMHLM_00258 5.5e-239 larA 5.1.2.1 S Domain of unknown function (DUF2088)
HAFJMHLM_00259 2.1e-118 larB S AIR carboxylase
HAFJMHLM_00260 2e-130 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HAFJMHLM_00261 9.6e-54 larC 4.99.1.12 S Protein of unknown function DUF111
HAFJMHLM_00262 1.1e-106 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HAFJMHLM_00263 2.7e-149 larE S NAD synthase
HAFJMHLM_00264 6.7e-90 L Transposase
HAFJMHLM_00265 9.2e-69 L Transposase
HAFJMHLM_00266 1.4e-161 lysA2 M Glycosyl hydrolases family 25
HAFJMHLM_00267 2.2e-85 K Acetyltransferase (GNAT) domain
HAFJMHLM_00268 1.1e-22 L DDE superfamily endonuclease
HAFJMHLM_00269 3.6e-35 L PFAM Transposase
HAFJMHLM_00270 8.8e-61 L DDE superfamily endonuclease
HAFJMHLM_00271 1.1e-12 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HAFJMHLM_00272 8.8e-07 tcdC
HAFJMHLM_00273 1.6e-149 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HAFJMHLM_00274 1.4e-90 S ECF-type riboflavin transporter, S component
HAFJMHLM_00275 7e-20 gerD
HAFJMHLM_00276 8.7e-23 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HAFJMHLM_00277 4.2e-147 gor 1.8.1.7 C Glutathione reductase
HAFJMHLM_00278 5.4e-21 S Protein of unknown function (DUF3021)
HAFJMHLM_00279 8.2e-65 K LytTr DNA-binding domain protein
HAFJMHLM_00280 1.1e-144 ligA 2.7.7.7, 6.5.1.2 L EXOIII
HAFJMHLM_00281 6.7e-96 yyaQ S YjbR
HAFJMHLM_00283 3e-131 ydcF S Gram-negative-bacterium-type cell wall biogenesis
HAFJMHLM_00284 4.3e-106 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
HAFJMHLM_00285 2.1e-212 1.3.5.4 C FMN_bind
HAFJMHLM_00286 1.2e-39 D Filamentation induced by cAMP protein fic
HAFJMHLM_00287 1.1e-24
HAFJMHLM_00288 1.1e-147 3.4.17.13 V LD-carboxypeptidase
HAFJMHLM_00289 2.1e-263 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
HAFJMHLM_00290 5.5e-170
HAFJMHLM_00291 1.3e-136
HAFJMHLM_00292 4.5e-22
HAFJMHLM_00293 6.1e-111 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HAFJMHLM_00294 8.9e-136 prsW S Involved in the degradation of specific anti-sigma factors
HAFJMHLM_00295 3.1e-71 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HAFJMHLM_00296 2e-25 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HAFJMHLM_00297 5.2e-262 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
HAFJMHLM_00298 3e-268 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HAFJMHLM_00299 2e-166 E ABC transporter, ATP-binding protein
HAFJMHLM_00300 1.3e-76 K Transcriptional regulator
HAFJMHLM_00301 5e-09 1.6.5.2 GM NAD(P)H-binding
HAFJMHLM_00302 2.1e-61 1.6.5.2 GM NmrA-like family
HAFJMHLM_00303 1.9e-164 htpX O Peptidase family M48
HAFJMHLM_00304 7.8e-16 4.4.1.8 E Aminotransferase, class I
HAFJMHLM_00306 0.0 prtS 3.4.21.110, 3.4.21.96 O Belongs to the peptidase S8 family
HAFJMHLM_00307 9.8e-67 K GNAT family
HAFJMHLM_00308 1.2e-83
HAFJMHLM_00309 1.9e-99 dedA 3.1.3.1 S SNARE associated Golgi protein
HAFJMHLM_00310 2.7e-196 asnA 6.3.1.1 F aspartate--ammonia ligase
HAFJMHLM_00311 5.4e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HAFJMHLM_00312 1e-221 L COG3547 Transposase and inactivated derivatives
HAFJMHLM_00313 4.1e-104 galR K Transcriptional regulator
HAFJMHLM_00314 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HAFJMHLM_00315 0.0 lacS G Transporter
HAFJMHLM_00316 1.8e-54 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HAFJMHLM_00317 1e-156 xerD L Phage integrase, N-terminal SAM-like domain
HAFJMHLM_00318 1.4e-93 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HAFJMHLM_00319 1.8e-81 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HAFJMHLM_00320 7.5e-23
HAFJMHLM_00321 5.6e-244 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HAFJMHLM_00322 3.2e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HAFJMHLM_00323 2.3e-122 trmK 2.1.1.217 S SAM-dependent methyltransferase
HAFJMHLM_00324 4.5e-79 mutT 3.6.1.55 F NUDIX domain
HAFJMHLM_00325 2.6e-125 S Peptidase family M23
HAFJMHLM_00326 1.6e-52 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HAFJMHLM_00328 1.5e-20 gor 1.8.1.7 C Glutathione reductase
HAFJMHLM_00331 1.4e-14 S Protein containing von Willebrand factor type A (VWA) domain
HAFJMHLM_00333 4.2e-178 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HAFJMHLM_00334 1.1e-243 lysC 2.7.2.4 E Belongs to the aspartokinase family
HAFJMHLM_00335 6.8e-69 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HAFJMHLM_00336 4.1e-217 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HAFJMHLM_00337 8.3e-168 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HAFJMHLM_00338 1.3e-137 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HAFJMHLM_00339 1.8e-215 patA 2.6.1.1 E Aminotransferase
HAFJMHLM_00340 5e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HAFJMHLM_00341 1.9e-76 S SLAP domain
HAFJMHLM_00342 1.5e-103 ydaF J Acetyltransferase (GNAT) domain
HAFJMHLM_00343 2.1e-71 dagK I Diacylglycerol kinase catalytic domain
HAFJMHLM_00344 7.7e-27 S Motility quorum-sensing regulator, toxin of MqsA
HAFJMHLM_00345 1.7e-117 ps301 K Protein of unknown function (DUF4065)
HAFJMHLM_00346 9.1e-207 V FtsX-like permease family
HAFJMHLM_00347 2.8e-95 V FtsX-like permease family
HAFJMHLM_00348 2.2e-126 cysA V ABC transporter, ATP-binding protein
HAFJMHLM_00350 2e-39
HAFJMHLM_00352 1.3e-22 S Phage Mu protein F like protein
HAFJMHLM_00353 4.3e-46 S Psort location CytoplasmicMembrane, score
HAFJMHLM_00354 6.9e-09 S Psort location CytoplasmicMembrane, score
HAFJMHLM_00355 7.8e-104 cylB U ABC-2 type transporter
HAFJMHLM_00356 1.4e-43 cylA V ABC transporter
HAFJMHLM_00357 2.5e-53 XK27_03610 K Acetyltransferase (GNAT) domain
HAFJMHLM_00358 7.6e-104 L Integrase
HAFJMHLM_00359 1.5e-67 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HAFJMHLM_00360 5.7e-54 V drug transmembrane transporter activity
HAFJMHLM_00361 1.9e-12 T diguanylate cyclase activity
HAFJMHLM_00362 2.3e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HAFJMHLM_00363 0.0 carB 6.3.5.5 F Psort location Cytoplasmic, score 8.87
HAFJMHLM_00364 1.2e-103 ybaJ Q Methyltransferase domain
HAFJMHLM_00365 1.1e-182 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
HAFJMHLM_00366 9.4e-80 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
HAFJMHLM_00367 2.6e-121 WQ51_05710 S Mitochondrial biogenesis AIM24
HAFJMHLM_00368 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HAFJMHLM_00369 1.1e-234 pbuG S permease
HAFJMHLM_00370 9.1e-192 add 3.5.4.2, 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HAFJMHLM_00371 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HAFJMHLM_00372 1.9e-119 srtA 3.4.22.70 M sortase family
HAFJMHLM_00373 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HAFJMHLM_00374 4.5e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HAFJMHLM_00375 5.3e-47 K DNA-binding transcription factor activity
HAFJMHLM_00376 6.1e-152 czcD P cation diffusion facilitator family transporter
HAFJMHLM_00377 2.6e-199 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HAFJMHLM_00378 6.1e-181 S AI-2E family transporter
HAFJMHLM_00379 1.4e-14 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HAFJMHLM_00380 1.2e-111 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HAFJMHLM_00381 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
HAFJMHLM_00382 1.4e-158 lysR5 K LysR substrate binding domain
HAFJMHLM_00383 7.4e-259 glnPH2 P ABC transporter permease
HAFJMHLM_00384 3.4e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HAFJMHLM_00385 5.2e-102 S Protein of unknown function (DUF4230)
HAFJMHLM_00386 8e-15 yjgN S Bacterial protein of unknown function (DUF898)
HAFJMHLM_00387 1.7e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HAFJMHLM_00388 1.8e-145 yitS S Uncharacterised protein, DegV family COG1307
HAFJMHLM_00389 1.4e-99 3.6.1.27 I Acid phosphatase homologues
HAFJMHLM_00390 2.2e-156
HAFJMHLM_00391 1.2e-160 lysR7 K LysR substrate binding domain
HAFJMHLM_00392 1.4e-304 yfiB1 V ABC transporter, ATP-binding protein
HAFJMHLM_00393 0.0 XK27_10035 V ABC transporter
HAFJMHLM_00394 1.3e-38 yliE T Putative diguanylate phosphodiesterase
HAFJMHLM_00396 1.4e-167 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HAFJMHLM_00397 4.7e-216 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HAFJMHLM_00398 6.9e-116 hlyIII S protein, hemolysin III
HAFJMHLM_00399 3.1e-153 DegV S Uncharacterised protein, DegV family COG1307
HAFJMHLM_00400 4.6e-35 yozE S Belongs to the UPF0346 family
HAFJMHLM_00401 1.9e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HAFJMHLM_00402 5.9e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HAFJMHLM_00403 3.5e-123 L Transposase
HAFJMHLM_00404 3.2e-69 L Transposase
HAFJMHLM_00405 9.2e-64 S Uncharacterised protein family (UPF0236)
HAFJMHLM_00406 8.7e-90 S Uncharacterised protein family (UPF0236)
HAFJMHLM_00407 1.5e-257 S Domain of unknown function (DUF4430)
HAFJMHLM_00408 1.3e-180 U FFAT motif binding
HAFJMHLM_00409 1.2e-69 S Domain of unknown function (DUF4430)
HAFJMHLM_00410 9.3e-13 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HAFJMHLM_00411 7.6e-264 L Putative transposase DNA-binding domain
HAFJMHLM_00413 2e-99 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HAFJMHLM_00414 0.0 pepF E oligoendopeptidase F
HAFJMHLM_00415 2.2e-173 L Putative transposase DNA-binding domain
HAFJMHLM_00416 4.2e-28 L Putative transposase DNA-binding domain
HAFJMHLM_00417 1.4e-201 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HAFJMHLM_00418 2.9e-15
HAFJMHLM_00419 9.9e-291 S ABC transporter, ATP-binding protein
HAFJMHLM_00420 1.7e-120 thrE S Putative threonine/serine exporter
HAFJMHLM_00421 1.1e-83 S Threonine/Serine exporter, ThrE
HAFJMHLM_00422 4.7e-08 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HAFJMHLM_00424 5.5e-15 M NLP P60 protein
HAFJMHLM_00425 4.6e-27 tcmJ G Cupin
HAFJMHLM_00426 2.3e-18 tcmJ G Cupin
HAFJMHLM_00427 1.1e-155 L Probable transposase
HAFJMHLM_00428 1.4e-74
HAFJMHLM_00429 6.5e-108
HAFJMHLM_00430 3.5e-288 S O-antigen ligase like membrane protein
HAFJMHLM_00431 6.2e-41
HAFJMHLM_00432 3.8e-96 gmk2 2.7.4.8 F Guanylate kinase homologues.
HAFJMHLM_00433 9e-81 M NlpC P60 family
HAFJMHLM_00434 1e-198 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HAFJMHLM_00435 1e-68 M NlpC/P60 family
HAFJMHLM_00436 3.4e-106 M NlpC/P60 family
HAFJMHLM_00437 1.7e-62 M NlpC P60 family protein
HAFJMHLM_00438 2.9e-94 M NlpC P60 family protein
HAFJMHLM_00439 7.3e-117 M NlpC P60 family protein
HAFJMHLM_00440 1.4e-226 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HAFJMHLM_00441 1e-174 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HAFJMHLM_00442 2e-110 epsB M biosynthesis protein
HAFJMHLM_00443 8.4e-113 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HAFJMHLM_00444 3.1e-144 ywqE 3.1.3.48 GM PHP domain protein
HAFJMHLM_00445 1.1e-122 rfbP M Bacterial sugar transferase
HAFJMHLM_00446 2e-85 wbbL S Glycosyl transferase family 2
HAFJMHLM_00447 1.2e-60 GT2 M Glycosyl transferase, family 2
HAFJMHLM_00448 5.4e-09 S EpsG family
HAFJMHLM_00449 1.1e-67 cps1B GT2,GT4 M Glycosyl transferases group 1
HAFJMHLM_00450 5.4e-28 cps1B GT2,GT4 M Glycosyl transferases group 1
HAFJMHLM_00451 3.1e-37
HAFJMHLM_00452 4.9e-92 wbbI M transferase activity, transferring glycosyl groups
HAFJMHLM_00453 1.2e-100 M transferase activity, transferring glycosyl groups
HAFJMHLM_00454 7.1e-248 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HAFJMHLM_00455 2.6e-42
HAFJMHLM_00456 8.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HAFJMHLM_00457 1.3e-251 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
HAFJMHLM_00458 9.7e-65 S Domain of unknown function (DUF1934)
HAFJMHLM_00459 5.3e-43 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HAFJMHLM_00460 1.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HAFJMHLM_00461 4.8e-235 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HAFJMHLM_00462 1.6e-41 rpmE2 J Ribosomal protein L31
HAFJMHLM_00463 1.8e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HAFJMHLM_00464 1.6e-229 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HAFJMHLM_00465 7.9e-70 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HAFJMHLM_00466 4.9e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HAFJMHLM_00467 7.7e-126 S (CBS) domain
HAFJMHLM_00468 4.8e-102 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HAFJMHLM_00469 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HAFJMHLM_00470 3.2e-34 yabO J S4 domain protein
HAFJMHLM_00471 2.2e-58 divIC D Septum formation initiator
HAFJMHLM_00472 1.7e-60 yabR J S1 RNA binding domain
HAFJMHLM_00473 4.9e-243 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HAFJMHLM_00474 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HAFJMHLM_00475 8.4e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HAFJMHLM_00476 3.6e-299 E ABC transporter, substratebinding protein
HAFJMHLM_00477 1.6e-246 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HAFJMHLM_00478 7e-192 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HAFJMHLM_00479 1.2e-275 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HAFJMHLM_00481 1.1e-34 T diguanylate cyclase activity
HAFJMHLM_00483 1.7e-198 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HAFJMHLM_00484 0.0 yjbQ P TrkA C-terminal domain protein
HAFJMHLM_00485 6.1e-267 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
HAFJMHLM_00486 4.2e-188 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HAFJMHLM_00487 4e-34 S Protein of unknown function (DUF2922)
HAFJMHLM_00488 3.4e-29
HAFJMHLM_00489 7.4e-79
HAFJMHLM_00490 6.5e-72
HAFJMHLM_00491 0.0 kup P Transport of potassium into the cell
HAFJMHLM_00492 0.0 pepO 3.4.24.71 O Peptidase family M13
HAFJMHLM_00493 2.7e-60 Z012_07300 O Glutaredoxin-related protein
HAFJMHLM_00494 7.4e-225 yttB EGP Major facilitator Superfamily
HAFJMHLM_00495 1.6e-164 XK27_04775 S PAS domain
HAFJMHLM_00496 1.6e-57 S Iron-sulfur cluster assembly protein
HAFJMHLM_00497 2.2e-139 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HAFJMHLM_00498 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HAFJMHLM_00499 2.2e-248 yxbA 6.3.1.12 S ATP-grasp enzyme
HAFJMHLM_00500 0.0 asnB 6.3.5.4 E Asparagine synthase
HAFJMHLM_00501 1.1e-272 S Calcineurin-like phosphoesterase
HAFJMHLM_00502 2.5e-83
HAFJMHLM_00503 1.5e-95 oppA E ABC transporter, substratebinding protein
HAFJMHLM_00504 4.7e-152 oppA E ABC transporter, substratebinding protein
HAFJMHLM_00505 1.9e-147 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HAFJMHLM_00506 2.6e-125 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HAFJMHLM_00507 5e-134 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HAFJMHLM_00508 3.8e-152 phnD P Phosphonate ABC transporter
HAFJMHLM_00509 5.5e-83 uspA T universal stress protein
HAFJMHLM_00510 3.1e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
HAFJMHLM_00511 9.5e-83 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HAFJMHLM_00512 3.3e-88 ntd 2.4.2.6 F Nucleoside
HAFJMHLM_00513 8.3e-218 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HAFJMHLM_00514 2.3e-10 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HAFJMHLM_00515 2e-181 K AI-2E family transporter
HAFJMHLM_00516 4.4e-303 S Predicted membrane protein (DUF2207)
HAFJMHLM_00517 2.3e-09
HAFJMHLM_00518 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HAFJMHLM_00519 7.5e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
HAFJMHLM_00520 3.6e-73 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HAFJMHLM_00521 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HAFJMHLM_00522 1.2e-169 prmA J Ribosomal protein L11 methyltransferase
HAFJMHLM_00523 5.1e-87 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HAFJMHLM_00524 4.3e-221 yjjP S Putative threonine/serine exporter
HAFJMHLM_00525 4.8e-221 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HAFJMHLM_00526 3e-210 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HAFJMHLM_00527 2.6e-192 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
HAFJMHLM_00528 2.5e-223 sptS 2.7.13.3 T Histidine kinase
HAFJMHLM_00529 1.1e-116 K response regulator
HAFJMHLM_00530 9.8e-109 2.7.6.5 T Region found in RelA / SpoT proteins
HAFJMHLM_00531 5.1e-151 cas2 2.7.7.7 L CRISPR-associated protein (Cas_Cas2CT1978)
HAFJMHLM_00532 6.3e-171 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HAFJMHLM_00533 4.5e-117 casE S CRISPR_assoc
HAFJMHLM_00534 1.2e-126 casD S CRISPR-associated protein (Cas_Cas5)
HAFJMHLM_00535 7.1e-179 casC L CT1975-like protein
HAFJMHLM_00536 2e-106 casB S CRISPR-associated protein Cse2 (CRISPR_cse2)
HAFJMHLM_00537 0.0 casA L the current gene model (or a revised gene model) may contain a frame shift
HAFJMHLM_00538 0.0 cas3 L CRISPR-associated helicase cas3
HAFJMHLM_00540 2.7e-19
HAFJMHLM_00541 1.1e-30 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HAFJMHLM_00542 2.4e-229 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HAFJMHLM_00543 9.3e-161 S Alpha/beta hydrolase of unknown function (DUF915)
HAFJMHLM_00544 9.2e-147 S Sucrose-6F-phosphate phosphohydrolase
HAFJMHLM_00545 2.8e-24 puuD S peptidase C26
HAFJMHLM_00546 4.4e-100 puuD S peptidase C26
HAFJMHLM_00547 1.9e-156 yicL EG EamA-like transporter family
HAFJMHLM_00548 3.1e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HAFJMHLM_00549 9.3e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HAFJMHLM_00550 1.2e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HAFJMHLM_00551 3.2e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HAFJMHLM_00552 4.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HAFJMHLM_00553 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HAFJMHLM_00554 3.3e-59 brnQ U Component of the transport system for branched-chain amino acids
HAFJMHLM_00555 1.7e-24 brnQ U Component of the transport system for branched-chain amino acids
HAFJMHLM_00556 2.6e-20 5.99.1.2 T diguanylate cyclase
HAFJMHLM_00557 5.6e-73 5.99.1.2 T diguanylate cyclase
HAFJMHLM_00558 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
HAFJMHLM_00559 6.4e-19
HAFJMHLM_00560 9.3e-129 cobQ S glutamine amidotransferase
HAFJMHLM_00561 3e-244 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HAFJMHLM_00562 1.1e-141 ptp2 3.1.3.48 T Tyrosine phosphatase family
HAFJMHLM_00563 6.1e-288 V ABC-type multidrug transport system, ATPase and permease components
HAFJMHLM_00564 2.4e-144 ptp2 3.1.3.48 T Tyrosine phosphatase family
HAFJMHLM_00565 2.2e-90 ymdB S Macro domain protein
HAFJMHLM_00566 4.1e-34
HAFJMHLM_00567 4.4e-145
HAFJMHLM_00569 4.6e-263 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HAFJMHLM_00570 2e-253 P Sodium:sulfate symporter transmembrane region
HAFJMHLM_00571 9.2e-169 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HAFJMHLM_00572 0.0 dnaK O Heat shock 70 kDa protein
HAFJMHLM_00573 1.7e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HAFJMHLM_00574 3.7e-180 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HAFJMHLM_00575 1.4e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HAFJMHLM_00576 2.2e-165 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HAFJMHLM_00577 5.5e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HAFJMHLM_00578 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HAFJMHLM_00579 4.5e-40 rplGA J ribosomal protein
HAFJMHLM_00580 7.3e-43 ylxR K Protein of unknown function (DUF448)
HAFJMHLM_00581 1e-189 nusA K Participates in both transcription termination and antitermination
HAFJMHLM_00582 7.2e-83 rimP J Required for maturation of 30S ribosomal subunits
HAFJMHLM_00583 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HAFJMHLM_00584 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HAFJMHLM_00585 1.8e-226 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HAFJMHLM_00586 1.4e-142 cdsA 2.7.7.41 S Belongs to the CDS family
HAFJMHLM_00587 1.9e-119 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HAFJMHLM_00588 1.6e-89 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HAFJMHLM_00589 4.1e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HAFJMHLM_00590 3.5e-183 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HAFJMHLM_00591 9.9e-135 rpsB J Belongs to the universal ribosomal protein uS2 family
HAFJMHLM_00592 8.4e-190 yabB 2.1.1.223 L Methyltransferase small domain
HAFJMHLM_00593 3.6e-111 plsC 2.3.1.51 I Acyltransferase
HAFJMHLM_00594 4.1e-181 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HAFJMHLM_00595 6.2e-249 yclM 2.7.2.4 E Belongs to the aspartokinase family
HAFJMHLM_00596 1.3e-210 hom 1.1.1.3 E homoserine dehydrogenase
HAFJMHLM_00597 1.2e-68 pheB 5.4.99.5 S Belongs to the UPF0735 family
HAFJMHLM_00598 6.3e-28 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
HAFJMHLM_00599 3.6e-70 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
HAFJMHLM_00600 9.2e-17 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
HAFJMHLM_00601 3e-58 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
HAFJMHLM_00602 6.7e-262 frdC 1.3.5.4 C FAD binding domain
HAFJMHLM_00603 4.5e-113 metI P ABC transporter permease
HAFJMHLM_00604 1.4e-184 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HAFJMHLM_00605 5.6e-118 metQ2 P Belongs to the nlpA lipoprotein family
HAFJMHLM_00606 0.0 aha1 P E1-E2 ATPase
HAFJMHLM_00607 6.5e-87 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HAFJMHLM_00608 4.8e-187 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HAFJMHLM_00609 4.6e-148 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HAFJMHLM_00610 5.4e-65
HAFJMHLM_00611 0.0 E ABC transporter, substratebinding protein
HAFJMHLM_00613 4.4e-123 pnb C nitroreductase
HAFJMHLM_00615 7e-255 I Protein of unknown function (DUF2974)
HAFJMHLM_00616 8.5e-105 engB D Necessary for normal cell division and for the maintenance of normal septation
HAFJMHLM_00617 3.2e-231 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HAFJMHLM_00618 7.6e-207 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HAFJMHLM_00619 1.2e-222 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HAFJMHLM_00620 1.6e-146
HAFJMHLM_00621 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HAFJMHLM_00622 2.3e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HAFJMHLM_00623 4.7e-33 rpsT J Binds directly to 16S ribosomal RNA
HAFJMHLM_00624 2.7e-177 holA 2.7.7.7 L DNA polymerase III delta subunit
HAFJMHLM_00625 0.0 comEC S Competence protein ComEC
HAFJMHLM_00626 7.4e-66 comEA L Competence protein ComEA
HAFJMHLM_00627 8.8e-90 L Transposase and inactivated derivatives
HAFJMHLM_00628 1.7e-173 L Transposase and inactivated derivatives
HAFJMHLM_00629 2.2e-32 S Transposase C of IS166 homeodomain
HAFJMHLM_00630 4.4e-186 ylbL T Belongs to the peptidase S16 family
HAFJMHLM_00631 5.7e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HAFJMHLM_00632 6e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HAFJMHLM_00633 6.2e-52 ylbG S UPF0298 protein
HAFJMHLM_00634 3.9e-210 ftsW D Belongs to the SEDS family
HAFJMHLM_00635 0.0 typA T GTP-binding protein TypA
HAFJMHLM_00636 1.1e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HAFJMHLM_00637 3.6e-35 ykzG S Belongs to the UPF0356 family
HAFJMHLM_00638 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HAFJMHLM_00639 2.6e-247 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HAFJMHLM_00640 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HAFJMHLM_00641 1.2e-99 S Repeat protein
HAFJMHLM_00642 2.9e-122 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HAFJMHLM_00643 4.3e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HAFJMHLM_00644 1.2e-55 XK27_04120 S Putative amino acid metabolism
HAFJMHLM_00645 1.1e-212 iscS 2.8.1.7 E Aminotransferase class V
HAFJMHLM_00646 9.4e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HAFJMHLM_00647 3e-15
HAFJMHLM_00648 2.8e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HAFJMHLM_00649 1.5e-32 cspA K 'Cold-shock' DNA-binding domain
HAFJMHLM_00650 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HAFJMHLM_00651 1.4e-51 ylmH S S4 domain protein
HAFJMHLM_00652 2e-75 ylmH S S4 domain protein
HAFJMHLM_00653 4.2e-44 yggT S YGGT family
HAFJMHLM_00654 1.8e-64 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HAFJMHLM_00655 5.8e-210 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HAFJMHLM_00656 9.6e-237 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HAFJMHLM_00657 3.8e-143 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HAFJMHLM_00658 1.5e-203 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HAFJMHLM_00659 4.7e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HAFJMHLM_00660 6.8e-173 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HAFJMHLM_00661 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HAFJMHLM_00662 1.4e-51 ftsL D Cell division protein FtsL
HAFJMHLM_00663 2.2e-168 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HAFJMHLM_00664 1.3e-75 mraZ K Belongs to the MraZ family
HAFJMHLM_00665 1.3e-54 S Protein of unknown function (DUF3397)
HAFJMHLM_00666 1.8e-93 mreD
HAFJMHLM_00667 4.7e-133 mreC M Involved in formation and maintenance of cell shape
HAFJMHLM_00668 4.4e-175 mreB D cell shape determining protein MreB
HAFJMHLM_00669 9.5e-112 radC L DNA repair protein
HAFJMHLM_00670 2.2e-125 S Haloacid dehalogenase-like hydrolase
HAFJMHLM_00671 4.2e-231 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HAFJMHLM_00672 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HAFJMHLM_00673 7.3e-127 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HAFJMHLM_00674 7.9e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HAFJMHLM_00675 9.2e-217 iscS2 2.8.1.7 E Aminotransferase class V
HAFJMHLM_00676 6.6e-296 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HAFJMHLM_00677 1.1e-107 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HAFJMHLM_00678 1.6e-79 yueI S Protein of unknown function (DUF1694)
HAFJMHLM_00679 6.7e-240 rarA L recombination factor protein RarA
HAFJMHLM_00680 1.8e-41
HAFJMHLM_00681 2.3e-78 usp6 T universal stress protein
HAFJMHLM_00682 1.6e-216 rodA D Belongs to the SEDS family
HAFJMHLM_00683 5e-34 S Protein of unknown function (DUF2969)
HAFJMHLM_00684 2.6e-45 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HAFJMHLM_00685 2e-175 mbl D Cell shape determining protein MreB Mrl
HAFJMHLM_00686 3.9e-32 ywzB S Protein of unknown function (DUF1146)
HAFJMHLM_00687 8.5e-70 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HAFJMHLM_00688 1.2e-245 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HAFJMHLM_00689 2.3e-168 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HAFJMHLM_00690 1e-276 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HAFJMHLM_00691 8.7e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HAFJMHLM_00692 2.2e-53 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HAFJMHLM_00693 8.5e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HAFJMHLM_00694 1e-125 atpB C it plays a direct role in the translocation of protons across the membrane
HAFJMHLM_00695 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HAFJMHLM_00696 3.3e-186 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HAFJMHLM_00697 1.1e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HAFJMHLM_00698 2.1e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HAFJMHLM_00699 3.2e-112 tdk 2.7.1.21 F thymidine kinase
HAFJMHLM_00700 8.7e-259 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
HAFJMHLM_00701 9.5e-34
HAFJMHLM_00702 7.1e-189 ampC V Beta-lactamase
HAFJMHLM_00705 2.8e-17 oppA E ABC transporter, substratebinding protein
HAFJMHLM_00706 9e-205 oppA E ABC transporter, substratebinding protein
HAFJMHLM_00707 1.4e-256 pgi 5.3.1.9 G Belongs to the GPI family
HAFJMHLM_00708 3.9e-113 vanZ V VanZ like family
HAFJMHLM_00709 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HAFJMHLM_00710 2.7e-267 T PhoQ Sensor
HAFJMHLM_00711 8.9e-133 K Transcriptional regulatory protein, C terminal
HAFJMHLM_00714 1.3e-218 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HAFJMHLM_00715 4e-184 ytxK 2.1.1.72 L N-6 DNA Methylase
HAFJMHLM_00716 7.3e-11 comGF U Putative Competence protein ComGF
HAFJMHLM_00718 9.6e-74
HAFJMHLM_00719 6.5e-51 comGC U competence protein ComGC
HAFJMHLM_00720 1.6e-156 comGB NU type II secretion system
HAFJMHLM_00721 7.8e-177 comGA NU Type II IV secretion system protein
HAFJMHLM_00722 6e-129 yebC K Transcriptional regulatory protein
HAFJMHLM_00723 2.8e-88 S VanZ like family
HAFJMHLM_00724 2.2e-157 psaA P Belongs to the bacterial solute-binding protein 9 family
HAFJMHLM_00725 8.4e-159 rssA S Phospholipase, patatin family
HAFJMHLM_00726 3.2e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HAFJMHLM_00727 3.3e-17 E Amino acid permease
HAFJMHLM_00728 2.4e-253 E Amino acid permease
HAFJMHLM_00729 1.7e-65
HAFJMHLM_00731 5e-103
HAFJMHLM_00732 6.9e-116 V AAA domain, putative AbiEii toxin, Type IV TA system
HAFJMHLM_00733 1.1e-16
HAFJMHLM_00734 2.4e-272 pipD E Dipeptidase
HAFJMHLM_00735 2.9e-96 K WHG domain
HAFJMHLM_00736 9.9e-97 nqr 1.5.1.36 S NADPH-dependent FMN reductase
HAFJMHLM_00737 1.6e-94 azr 1.5.1.36 S NADPH-dependent FMN reductase
HAFJMHLM_00738 4.7e-140 3.1.3.48 T Tyrosine phosphatase family
HAFJMHLM_00739 4.1e-186 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HAFJMHLM_00740 2.2e-85 cvpA S Colicin V production protein
HAFJMHLM_00741 2.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HAFJMHLM_00742 7.4e-144 noc K Belongs to the ParB family
HAFJMHLM_00743 2.6e-138 soj D Sporulation initiation inhibitor
HAFJMHLM_00744 2.5e-153 spo0J K Belongs to the ParB family
HAFJMHLM_00745 2.1e-44 yyzM S Bacterial protein of unknown function (DUF951)
HAFJMHLM_00746 2.3e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HAFJMHLM_00747 7.7e-135 XK27_01040 S Protein of unknown function (DUF1129)
HAFJMHLM_00748 1.9e-306 V ABC transporter, ATP-binding protein
HAFJMHLM_00749 0.0 ndvA V ABC transporter
HAFJMHLM_00750 2.8e-120 K response regulator
HAFJMHLM_00751 1.5e-217 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
HAFJMHLM_00752 6.2e-293 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HAFJMHLM_00753 5.2e-144 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HAFJMHLM_00754 1.2e-129 fruR K DeoR C terminal sensor domain
HAFJMHLM_00755 2.2e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HAFJMHLM_00756 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
HAFJMHLM_00757 1.5e-141 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
HAFJMHLM_00758 6.1e-117 fhuC P ABC transporter
HAFJMHLM_00759 4.4e-133 znuB U ABC 3 transport family
HAFJMHLM_00761 4.1e-54 pdxH S Pyridoxamine 5'-phosphate oxidase
HAFJMHLM_00762 1.1e-108 P Cobalt transport protein
HAFJMHLM_00763 3.7e-249 cbiO1 S ABC transporter, ATP-binding protein
HAFJMHLM_00764 5.2e-265 emrY EGP Major facilitator Superfamily
HAFJMHLM_00765 6.5e-151 K helix_turn_helix, arabinose operon control protein
HAFJMHLM_00766 8.5e-61 natA1 S ABC transporter
HAFJMHLM_00767 8.7e-50 L Winged helix-turn helix
HAFJMHLM_00769 1.1e-86 L An automated process has identified a potential problem with this gene model
HAFJMHLM_00770 2.1e-147 htpX O Belongs to the peptidase M48B family
HAFJMHLM_00771 6.8e-93 lemA S LemA family
HAFJMHLM_00772 1.2e-200 ybiR P Citrate transporter
HAFJMHLM_00773 5.3e-15
HAFJMHLM_00774 5.8e-174 L HNH nucleases
HAFJMHLM_00775 8.2e-104 CBM50 M NlpC P60 family protein
HAFJMHLM_00776 1.1e-136 glnQ E ABC transporter, ATP-binding protein
HAFJMHLM_00777 2.2e-269 glnP P ABC transporter permease
HAFJMHLM_00778 7.9e-122 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HAFJMHLM_00779 1.8e-65 yeaO S Protein of unknown function, DUF488
HAFJMHLM_00780 3.2e-132 cobB K SIR2 family
HAFJMHLM_00781 4.9e-79
HAFJMHLM_00782 9.7e-280 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HAFJMHLM_00783 2.6e-177 S Alpha/beta hydrolase of unknown function (DUF915)
HAFJMHLM_00784 1.2e-124 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HAFJMHLM_00785 1.4e-157 ypuA S Protein of unknown function (DUF1002)
HAFJMHLM_00786 4.6e-141 epsV 2.7.8.12 S glycosyl transferase family 2
HAFJMHLM_00787 3.4e-123 S Alpha/beta hydrolase family
HAFJMHLM_00788 8.9e-184 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HAFJMHLM_00789 9.5e-121 luxT K Bacterial regulatory proteins, tetR family
HAFJMHLM_00790 3.2e-134
HAFJMHLM_00791 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
HAFJMHLM_00792 8.7e-151 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HAFJMHLM_00794 5.1e-131
HAFJMHLM_00795 4.8e-07
HAFJMHLM_00796 7.3e-83 K DNA-templated transcription, initiation
HAFJMHLM_00797 8.2e-131 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HAFJMHLM_00798 1.7e-31 scrR K Periplasmic binding protein domain
HAFJMHLM_00799 9.8e-27 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
HAFJMHLM_00800 4.4e-139 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
HAFJMHLM_00801 3.3e-203 S Bacterial membrane protein, YfhO
HAFJMHLM_00802 3.8e-168 yfdH GT2 M Glycosyltransferase like family 2
HAFJMHLM_00803 9.9e-12 T diguanylate cyclase activity
HAFJMHLM_00804 2.2e-85 racA K Domain of unknown function (DUF1836)
HAFJMHLM_00805 2.3e-142 yitS S EDD domain protein, DegV family
HAFJMHLM_00806 1.2e-07 yliE T Putative diguanylate phosphodiesterase
HAFJMHLM_00807 1.2e-101 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
HAFJMHLM_00808 2.2e-122 gpmB G Phosphoglycerate mutase family
HAFJMHLM_00809 8.1e-13
HAFJMHLM_00810 2e-50
HAFJMHLM_00811 1.7e-48
HAFJMHLM_00812 1.3e-42
HAFJMHLM_00813 5.5e-87 S biotin transmembrane transporter activity
HAFJMHLM_00814 4.9e-136 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HAFJMHLM_00815 1.9e-91 L haloacid dehalogenase-like hydrolase
HAFJMHLM_00816 5.1e-161 xth 3.1.11.2 L exodeoxyribonuclease III
HAFJMHLM_00817 3.1e-74
HAFJMHLM_00818 4.2e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HAFJMHLM_00819 2.2e-162 yvgN C Aldo keto reductase
HAFJMHLM_00820 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
HAFJMHLM_00821 2e-13 S Domain of unknown function (DUF4430)
HAFJMHLM_00822 4.7e-94 S ECF transporter, substrate-specific component
HAFJMHLM_00823 9.4e-98 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
HAFJMHLM_00824 6.5e-23 ytdP K Transcriptional regulator
HAFJMHLM_00825 1.4e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HAFJMHLM_00826 1.6e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HAFJMHLM_00827 1.3e-122 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HAFJMHLM_00828 9.1e-215 ecsB U ABC transporter
HAFJMHLM_00829 1.2e-135 ecsA V ABC transporter, ATP-binding protein
HAFJMHLM_00830 2.1e-76 hit FG Scavenger mRNA decapping enzyme C-term binding
HAFJMHLM_00831 4e-54
HAFJMHLM_00832 6.2e-163 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HAFJMHLM_00833 1.3e-131 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HAFJMHLM_00834 1.3e-111 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HAFJMHLM_00835 1.7e-149 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HAFJMHLM_00836 6.6e-33 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HAFJMHLM_00837 4.3e-34 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F shikimate kinase activity
HAFJMHLM_00838 2e-177 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
HAFJMHLM_00839 0.0 L AAA domain
HAFJMHLM_00840 1.2e-219 yhaO L Ser Thr phosphatase family protein
HAFJMHLM_00841 8.3e-52 yheA S Belongs to the UPF0342 family
HAFJMHLM_00842 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HAFJMHLM_00843 3.2e-158 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HAFJMHLM_00844 5.6e-169 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HAFJMHLM_00845 4.6e-94 M ErfK YbiS YcfS YnhG
HAFJMHLM_00846 2.6e-51 3.4.22.70 M Sortase family
HAFJMHLM_00847 2.3e-73 L Putative transposase DNA-binding domain
HAFJMHLM_00848 7.1e-11 L An automated process has identified a potential problem with this gene model
HAFJMHLM_00850 4.3e-193 M ErfK YbiS YcfS YnhG
HAFJMHLM_00851 1.2e-155 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HAFJMHLM_00852 1.6e-225 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HAFJMHLM_00854 8.9e-81 1.2.3.3, 3.7.1.22 EH Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
HAFJMHLM_00855 1.9e-167 glk 2.7.1.2 G Glucokinase
HAFJMHLM_00856 1.7e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HAFJMHLM_00857 1.5e-212 naiP EGP Major facilitator Superfamily
HAFJMHLM_00858 1.7e-65 S Membrane
HAFJMHLM_00859 2e-185 1.3.5.4 C FAD binding domain
HAFJMHLM_00860 1.1e-164 K Transcriptional regulator, LysR family
HAFJMHLM_00861 1.3e-146 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HAFJMHLM_00862 4.7e-60 K LysR substrate binding domain
HAFJMHLM_00863 4.2e-182 ybfG M peptidoglycan-binding domain-containing protein
HAFJMHLM_00865 2.9e-09
HAFJMHLM_00866 1.9e-166 arbZ I Phosphate acyltransferases
HAFJMHLM_00867 1.1e-152 arbx M Glycosyl transferase family 8
HAFJMHLM_00868 9.8e-146 arbV 2.3.1.51 I Acyl-transferase
HAFJMHLM_00870 2.4e-130 K response regulator
HAFJMHLM_00871 0.0 vicK 2.7.13.3 T Histidine kinase
HAFJMHLM_00872 9.2e-236 yycH S YycH protein
HAFJMHLM_00873 3.6e-135 yycI S YycH protein
HAFJMHLM_00874 4.1e-147 vicX 3.1.26.11 S domain protein
HAFJMHLM_00875 7.2e-154 htrA 3.4.21.107 O serine protease
HAFJMHLM_00876 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HAFJMHLM_00877 4.3e-116
HAFJMHLM_00879 1.3e-148 K Helix-turn-helix domain
HAFJMHLM_00880 6.8e-167
HAFJMHLM_00882 4.5e-169 oppA E ABC transporter, substratebinding protein
HAFJMHLM_00883 2.6e-36
HAFJMHLM_00884 1.9e-121 yliE T Putative diguanylate phosphodiesterase
HAFJMHLM_00886 1.1e-148 pstS P Phosphate
HAFJMHLM_00887 1.6e-160 pstC P probably responsible for the translocation of the substrate across the membrane
HAFJMHLM_00888 4.8e-157 pstA P Phosphate transport system permease protein PstA
HAFJMHLM_00889 3.5e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HAFJMHLM_00890 5.1e-108 phoU P Plays a role in the regulation of phosphate uptake
HAFJMHLM_00891 7.8e-123 T Transcriptional regulatory protein, C terminal
HAFJMHLM_00892 2.3e-301 phoR 2.7.13.3 T Histidine kinase
HAFJMHLM_00893 4.3e-55 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HAFJMHLM_00894 2.3e-55 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HAFJMHLM_00895 1.6e-136 lsa S ABC transporter
HAFJMHLM_00897 5e-119 3.6.1.13 L NUDIX domain
HAFJMHLM_00898 1.6e-23 S Glycosyl hydrolases family 18
HAFJMHLM_00899 5.8e-73 S Glycosyl hydrolases family 18
HAFJMHLM_00900 1.5e-103 I NUDIX domain
HAFJMHLM_00901 1.4e-59 S C4-dicarboxylate anaerobic carrier
HAFJMHLM_00902 7.8e-25 S C4-dicarboxylate anaerobic carrier
HAFJMHLM_00903 8.7e-16 S C4-dicarboxylate anaerobic carrier
HAFJMHLM_00904 2.2e-137 cbiO2 P ABC transporter
HAFJMHLM_00905 5.5e-147 P ABC transporter
HAFJMHLM_00906 4.1e-128 cbiQ P Cobalt transport protein
HAFJMHLM_00907 1.7e-100 2.7.7.65 T phosphorelay sensor kinase activity
HAFJMHLM_00908 3.3e-53 yliE T Putative diguanylate phosphodiesterase
HAFJMHLM_00909 5.4e-44 2.7.7.65 T diguanylate cyclase
HAFJMHLM_00910 4.2e-101
HAFJMHLM_00911 6.8e-150 supH G Sucrose-6F-phosphate phosphohydrolase
HAFJMHLM_00912 1.7e-14 K Winged helix DNA-binding domain
HAFJMHLM_00913 6.4e-20 lmrA V ABC transporter, ATP-binding protein
HAFJMHLM_00914 1.5e-55 V abc transporter atp-binding protein
HAFJMHLM_00915 7e-33 yfiC V ABC transporter
HAFJMHLM_00916 2.6e-166 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HAFJMHLM_00917 1.7e-213 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HAFJMHLM_00918 1.4e-08 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
HAFJMHLM_00919 3.7e-233 brnQ U Component of the transport system for branched-chain amino acids
HAFJMHLM_00920 1.6e-112 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HAFJMHLM_00921 2.7e-45 D Di-iron-containing protein involved in the repair of iron-sulfur clusters
HAFJMHLM_00922 5.6e-33 copZ P Heavy-metal-associated domain
HAFJMHLM_00923 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
HAFJMHLM_00924 4.4e-116 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HAFJMHLM_00925 4.8e-45 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HAFJMHLM_00926 2.4e-118 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
HAFJMHLM_00927 1.4e-27 L restriction endonuclease
HAFJMHLM_00928 9.3e-253 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HAFJMHLM_00929 3.2e-111 S Protein of unknown function (DUF1211)
HAFJMHLM_00930 3.7e-168 yegS 2.7.1.107 G Lipid kinase
HAFJMHLM_00931 1e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HAFJMHLM_00932 8.7e-265 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HAFJMHLM_00933 1.6e-46 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HAFJMHLM_00934 2.3e-191 camS S sex pheromone
HAFJMHLM_00935 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HAFJMHLM_00936 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HAFJMHLM_00937 3.7e-114 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
HAFJMHLM_00938 1.2e-101 S ECF transporter, substrate-specific component
HAFJMHLM_00940 5.8e-83 ydcK S Belongs to the SprT family
HAFJMHLM_00941 0.0 ydgH S MMPL family
HAFJMHLM_00942 4e-96 yobS K Bacterial regulatory proteins, tetR family
HAFJMHLM_00944 1e-154 3.5.2.6 V Beta-lactamase enzyme family
HAFJMHLM_00945 1.5e-148 corA P CorA-like Mg2+ transporter protein
HAFJMHLM_00946 1.4e-172 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
HAFJMHLM_00947 1.1e-87 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HAFJMHLM_00948 2.8e-105
HAFJMHLM_00949 8.9e-48 E dipeptidase activity
HAFJMHLM_00950 1.1e-123 endA F DNA RNA non-specific endonuclease
HAFJMHLM_00951 4.1e-156 dkg S reductase
HAFJMHLM_00953 2.8e-49 GK ROK family
HAFJMHLM_00954 2.9e-18 GK ROK family
HAFJMHLM_00955 1.3e-126 S PAS domain
HAFJMHLM_00956 2.6e-286 V ABC transporter transmembrane region
HAFJMHLM_00957 2e-189
HAFJMHLM_00958 3.5e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HAFJMHLM_00959 9.1e-70 ymfM S Helix-turn-helix domain
HAFJMHLM_00960 1.3e-96 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HAFJMHLM_00961 7.4e-169 coaA 2.7.1.33 F Pantothenic acid kinase
HAFJMHLM_00962 1.3e-102 E GDSL-like Lipase/Acylhydrolase
HAFJMHLM_00963 3.6e-16 T CHASE
HAFJMHLM_00964 1.6e-11 yeaJ 2.7.7.65 T CHASE
HAFJMHLM_00966 5.7e-39 L Transposase
HAFJMHLM_00967 9.2e-26
HAFJMHLM_00970 2.1e-96 S ABC transporter, ATP-binding protein
HAFJMHLM_00971 6.9e-77 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HAFJMHLM_00972 6.3e-46 higA K Helix-turn-helix XRE-family like proteins
HAFJMHLM_00973 1.3e-187 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HAFJMHLM_00974 4.8e-116 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HAFJMHLM_00975 7.7e-155 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HAFJMHLM_00976 2e-207 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HAFJMHLM_00977 5e-202 KQ Hypothetical methyltransferase
HAFJMHLM_00978 1.7e-56 K Bacterial regulatory proteins, tetR family
HAFJMHLM_00979 1.6e-78 S Membrane protein involved in the export of O-antigen and teichoic acid
HAFJMHLM_00980 8.1e-10
HAFJMHLM_00981 1.5e-155 F DNA/RNA non-specific endonuclease
HAFJMHLM_00982 1.7e-89 L nuclease
HAFJMHLM_00984 4.4e-32 K Bacterial regulatory proteins, tetR family
HAFJMHLM_00985 2e-117 mcrC V McrBC 5-methylcytosine restriction system component
HAFJMHLM_00986 0.0 mcrB V AAA domain (dynein-related subfamily)
HAFJMHLM_00987 1.4e-23
HAFJMHLM_00988 2.9e-119 S Membrane protein involved in the export of O-antigen and teichoic acid
HAFJMHLM_00989 3.5e-100 glf 5.4.99.9 M UDP-galactopyranose mutase
HAFJMHLM_00990 1.2e-39 glf 5.4.99.9 M UDP-galactopyranose mutase
HAFJMHLM_00991 7.4e-25 glf 5.4.99.9 M UDP-galactopyranose mutase
HAFJMHLM_00992 6.8e-147 cps1D M Domain of unknown function (DUF4422)
HAFJMHLM_00993 4.4e-115 rfbP 2.7.8.6 M Bacterial sugar transferase
HAFJMHLM_00994 1.5e-142 S Core-2/I-Branching enzyme
HAFJMHLM_00995 1.2e-25 camS S COG4851 Protein involved in sex pheromone biosynthesis
HAFJMHLM_00996 3.7e-222
HAFJMHLM_00997 3.8e-51
HAFJMHLM_00998 2.2e-140
HAFJMHLM_00999 0.0
HAFJMHLM_01000 2.9e-168 1.1.1.399, 1.1.1.95 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HAFJMHLM_01001 1e-70 K Transcriptional regulator, MarR family
HAFJMHLM_01002 1.8e-304 XK27_09600 V ABC transporter, ATP-binding protein
HAFJMHLM_01003 0.0 V ABC transporter transmembrane region
HAFJMHLM_01004 6.6e-45 P Rhodanese Homology Domain
HAFJMHLM_01009 1e-20 K LysR substrate binding domain
HAFJMHLM_01011 5.9e-42 yjdJ S GCN5-related N-acetyl-transferase
HAFJMHLM_01012 2.4e-130 gph 3.1.3.18 S HAD-hyrolase-like
HAFJMHLM_01013 7.3e-14 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
HAFJMHLM_01014 1.6e-43 adk 2.7.4.3 F topology modulation protein
HAFJMHLM_01015 1.2e-75 T Diguanylate cyclase, GGDEF domain
HAFJMHLM_01016 1.8e-32 tlpA2 L Transposase IS200 like
HAFJMHLM_01019 1.8e-74
HAFJMHLM_01020 1.3e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
HAFJMHLM_01021 6.2e-117 dedA S SNARE-like domain protein
HAFJMHLM_01022 1.4e-102 S Protein of unknown function (DUF1461)
HAFJMHLM_01023 9.1e-144 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HAFJMHLM_01024 4.1e-82 yutD S Protein of unknown function (DUF1027)
HAFJMHLM_01025 2e-274 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HAFJMHLM_01026 1.8e-56
HAFJMHLM_01027 3.5e-180 ccpA K catabolite control protein A
HAFJMHLM_01028 4.2e-211 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HAFJMHLM_01030 1.6e-40
HAFJMHLM_01031 2.7e-09 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HAFJMHLM_01032 2.2e-146 ykuT M mechanosensitive ion channel
HAFJMHLM_01033 2e-109 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HAFJMHLM_01034 1.1e-65 yslB S Protein of unknown function (DUF2507)
HAFJMHLM_01035 1.7e-53 trxA O Belongs to the thioredoxin family
HAFJMHLM_01036 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HAFJMHLM_01037 3e-40 yrzB S Belongs to the UPF0473 family
HAFJMHLM_01038 1.8e-72 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HAFJMHLM_01039 5.7e-42 yrzL S Belongs to the UPF0297 family
HAFJMHLM_01040 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HAFJMHLM_01041 3.9e-222 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HAFJMHLM_01042 2.9e-176 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HAFJMHLM_01043 1.1e-203 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HAFJMHLM_01044 1.4e-278 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HAFJMHLM_01045 2.2e-26 yajC U Preprotein translocase
HAFJMHLM_01046 8.1e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HAFJMHLM_01047 5.4e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HAFJMHLM_01048 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HAFJMHLM_01049 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HAFJMHLM_01050 1.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HAFJMHLM_01051 2.8e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HAFJMHLM_01052 2.5e-121 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HAFJMHLM_01053 3.4e-301 uup S ABC transporter, ATP-binding protein
HAFJMHLM_01054 2e-56 isp2 L Transposase
HAFJMHLM_01055 6.2e-188 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HAFJMHLM_01056 4.2e-92 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HAFJMHLM_01057 5.2e-125 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HAFJMHLM_01058 5.9e-86 folT S ECF transporter, substrate-specific component
HAFJMHLM_01059 5.9e-86 folT S ECF transporter, substrate-specific component
HAFJMHLM_01060 5e-139 fat 3.1.2.21 I Acyl-ACP thioesterase
HAFJMHLM_01061 2.5e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HAFJMHLM_01062 7.1e-53 yabA L Involved in initiation control of chromosome replication
HAFJMHLM_01063 1.2e-155 holB 2.7.7.7 L DNA polymerase III
HAFJMHLM_01064 4.7e-49 yaaQ S Cyclic-di-AMP receptor
HAFJMHLM_01065 8.4e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HAFJMHLM_01066 1.2e-33 S Protein of unknown function (DUF2508)
HAFJMHLM_01067 1.7e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HAFJMHLM_01068 3.5e-52 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HAFJMHLM_01069 1.5e-285 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HAFJMHLM_01070 1.1e-84 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HAFJMHLM_01071 2.5e-109 rsmC 2.1.1.172 J Methyltransferase
HAFJMHLM_01072 9.5e-76 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HAFJMHLM_01073 3.1e-173
HAFJMHLM_01074 3.9e-44
HAFJMHLM_01076 1.9e-14 L Helix-turn-helix domain
HAFJMHLM_01077 2.5e-203 pbpX1 V Beta-lactamase
HAFJMHLM_01078 4.5e-208 pbpX1 V Beta-lactamase
HAFJMHLM_01079 1.6e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HAFJMHLM_01080 1.9e-82 oppA E ABC transporter, substratebinding protein
HAFJMHLM_01081 5.2e-49 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HAFJMHLM_01082 1.2e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HAFJMHLM_01083 1.6e-67
HAFJMHLM_01084 3e-229 amtB P ammonium transporter
HAFJMHLM_01085 8.6e-187 S Glycosyl transferase family 2
HAFJMHLM_01086 7.5e-121 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HAFJMHLM_01087 6.9e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HAFJMHLM_01088 8.3e-99 nusG K Participates in transcription elongation, termination and antitermination
HAFJMHLM_01089 3.9e-23 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HAFJMHLM_01090 1e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HAFJMHLM_01091 5e-126 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HAFJMHLM_01092 2e-79 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HAFJMHLM_01093 3.7e-39 dxs 2.2.1.7 H 1-deoxy-D-xylulose-5-phosphate synthase activity
HAFJMHLM_01095 3.4e-32
HAFJMHLM_01096 1e-99 yvrI K sigma factor activity
HAFJMHLM_01097 4.2e-138 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HAFJMHLM_01098 2.7e-76 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HAFJMHLM_01099 6.1e-271 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HAFJMHLM_01100 1.5e-103 F NUDIX domain
HAFJMHLM_01101 9.5e-38 oppA E ABC transporter, substratebinding protein
HAFJMHLM_01102 8.5e-60 ytjP 3.5.1.18 E dipeptidase PepV
HAFJMHLM_01103 1.5e-158 K LysR substrate binding domain
HAFJMHLM_01104 1e-179 yeiH S Conserved hypothetical protein 698
HAFJMHLM_01105 1.9e-283 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HAFJMHLM_01107 2.8e-120 skfE V ATPases associated with a variety of cellular activities
HAFJMHLM_01108 9.6e-59 yvoA_1 K Transcriptional regulator, GntR family
HAFJMHLM_01109 2.6e-294 oppA E ABC transporter, substratebinding protein
HAFJMHLM_01110 2.2e-93 3.6.1.13 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HAFJMHLM_01111 1.1e-220 6.3.2.4 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HAFJMHLM_01112 2e-211 6.3.4.18, 6.3.5.5 F 5-(carboxyamino)imidazole ribonucleotide synthase activity
HAFJMHLM_01113 2.2e-151 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HAFJMHLM_01114 1e-185
HAFJMHLM_01115 4.5e-89 ydjH 2.7.1.15 G Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HAFJMHLM_01116 8.2e-21 ydjH 2.7.1.15 G Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HAFJMHLM_01117 6.9e-191 EGP Transmembrane secretion effector
HAFJMHLM_01118 7.8e-85 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HAFJMHLM_01119 1.2e-97 dnaQ 2.7.7.7 L DNA polymerase III
HAFJMHLM_01120 8.9e-159 murB 1.3.1.98 M Cell wall formation
HAFJMHLM_01121 1.3e-201 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HAFJMHLM_01122 3.4e-141 potB P ABC transporter permease
HAFJMHLM_01123 1.3e-124 potC P ABC transporter permease
HAFJMHLM_01124 5.4e-203 potD P ABC transporter
HAFJMHLM_01125 9.5e-147 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HAFJMHLM_01126 4.8e-155 ybbR S YbbR-like protein
HAFJMHLM_01127 1.1e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HAFJMHLM_01128 3.7e-148 S hydrolase
HAFJMHLM_01129 2.4e-24 V peptidase activity
HAFJMHLM_01130 3.2e-83 V Beta-lactamase
HAFJMHLM_01131 1.9e-69 atkY K Copper transport repressor CopY TcrY
HAFJMHLM_01132 3e-52 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HAFJMHLM_01133 0.0 copA 3.6.3.54 P P-type ATPase
HAFJMHLM_01134 1.8e-63 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HAFJMHLM_01135 4.2e-59 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HAFJMHLM_01136 9.5e-122
HAFJMHLM_01137 3.4e-133 T diguanylate cyclase activity
HAFJMHLM_01138 4e-99 yliE T Putative diguanylate phosphodiesterase
HAFJMHLM_01139 2.7e-59 yliE T EAL domain
HAFJMHLM_01140 1e-27 T Diguanylate cyclase, GGDEF domain
HAFJMHLM_01141 7.6e-36
HAFJMHLM_01142 6.9e-83 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HAFJMHLM_01143 1.5e-78 GM NmrA-like family
HAFJMHLM_01144 3.8e-95 S amidohydrolase
HAFJMHLM_01145 1.6e-110 XK27_07210 6.1.1.6 S B3 4 domain
HAFJMHLM_01146 6.7e-127 KT YcbB domain
HAFJMHLM_01147 1.9e-186 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HAFJMHLM_01148 3e-157 arcC 2.7.2.2 E Belongs to the carbamate kinase family
HAFJMHLM_01149 2.9e-82 arcA 3.5.3.6 E Arginine
HAFJMHLM_01150 2.5e-103 arcA 3.5.3.6 E Arginine
HAFJMHLM_01151 1.2e-242 E Arginine ornithine antiporter
HAFJMHLM_01177 7.1e-217 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
HAFJMHLM_01178 2.1e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
HAFJMHLM_01179 1e-174 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HAFJMHLM_01180 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HAFJMHLM_01181 2.9e-29 secG U Preprotein translocase
HAFJMHLM_01182 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HAFJMHLM_01183 8e-79 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HAFJMHLM_01186 9.5e-212 S FtsX-like permease family
HAFJMHLM_01187 7.1e-116 V ABC transporter, ATP-binding protein
HAFJMHLM_01190 4.8e-82 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HAFJMHLM_01191 8.2e-79 yjcF S Acetyltransferase (GNAT) domain
HAFJMHLM_01192 2.9e-142 sufC O FeS assembly ATPase SufC
HAFJMHLM_01193 1.1e-217 sufD O FeS assembly protein SufD
HAFJMHLM_01194 7.7e-222 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HAFJMHLM_01195 1.5e-71 nifU C SUF system FeS assembly protein, NifU family
HAFJMHLM_01196 1.3e-273 sufB O assembly protein SufB
HAFJMHLM_01197 2.5e-27 cydD V abc transporter atp-binding protein
HAFJMHLM_01198 6.3e-154 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HAFJMHLM_01199 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HAFJMHLM_01200 3.1e-170 phoH T phosphate starvation-inducible protein PhoH
HAFJMHLM_01201 3.3e-97 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HAFJMHLM_01202 1e-72 cdd 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HAFJMHLM_01203 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HAFJMHLM_01204 5.9e-132 recO L Involved in DNA repair and RecF pathway recombination
HAFJMHLM_01205 2.3e-178 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HAFJMHLM_01206 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HAFJMHLM_01207 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HAFJMHLM_01208 1.5e-195 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HAFJMHLM_01209 1.9e-195 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HAFJMHLM_01210 8e-197 K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HAFJMHLM_01212 3.3e-07 K LysR substrate binding domain
HAFJMHLM_01213 1.5e-114 L Putative transposase DNA-binding domain
HAFJMHLM_01214 8.1e-271 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HAFJMHLM_01215 8.5e-20 L Transposase DDE domain
HAFJMHLM_01216 6.6e-140 potB E Binding-protein-dependent transport system inner membrane component
HAFJMHLM_01217 5.5e-128 potC3 E Binding-protein-dependent transport system inner membrane component
HAFJMHLM_01218 6.2e-188 potA11 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HAFJMHLM_01219 6.5e-185 potD2 P ABC transporter
HAFJMHLM_01220 0.0 ade 3.5.4.2 F Adenine deaminase C-terminal domain
HAFJMHLM_01221 2.9e-188 tcsA S ABC transporter substrate-binding protein PnrA-like
HAFJMHLM_01222 1.3e-282 xylG 3.6.3.17 S ABC transporter
HAFJMHLM_01223 9.8e-203 yufP S Belongs to the binding-protein-dependent transport system permease family
HAFJMHLM_01224 5.4e-170 yufQ S Belongs to the binding-protein-dependent transport system permease family
HAFJMHLM_01225 1.9e-24 EGP Major facilitator Superfamily
HAFJMHLM_01227 1.8e-153 yeaE S Aldo/keto reductase family
HAFJMHLM_01228 6.2e-123 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HAFJMHLM_01230 1.1e-116 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HAFJMHLM_01231 8.3e-128 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HAFJMHLM_01232 5e-268 glnP P ABC transporter
HAFJMHLM_01233 5.5e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HAFJMHLM_01234 4.6e-35 fadF C COG0247 Fe-S oxidoreductase
HAFJMHLM_01235 1.2e-71 XK27_02470 K LytTr DNA-binding domain
HAFJMHLM_01236 1.4e-11 liaI S membrane
HAFJMHLM_01237 1.4e-115 aatB ET ABC transporter substrate-binding protein
HAFJMHLM_01238 3.7e-17 glnQ 3.6.3.21 E ABC transporter
HAFJMHLM_01239 0.0 helD 3.6.4.12 L DNA helicase
HAFJMHLM_01240 5.4e-113 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HAFJMHLM_01241 2e-123 pgm3 G Phosphoglycerate mutase family
HAFJMHLM_01242 3.4e-134 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HAFJMHLM_01243 6.4e-34
HAFJMHLM_01245 3.6e-265 3.1.4.46, 3.2.1.99 GH43 N domain, Protein
HAFJMHLM_01246 4.3e-106 L DNA recombination
HAFJMHLM_01247 5.6e-43 sidC L DNA recombination
HAFJMHLM_01248 1.9e-127 S VanZ like family
HAFJMHLM_01249 7.9e-73 mesH S Teichoic acid glycosylation protein
HAFJMHLM_01250 4.6e-79 S VanZ like family
HAFJMHLM_01251 5.4e-140 M NlpC/P60 family
HAFJMHLM_01252 4.8e-12 G Peptidase_C39 like family
HAFJMHLM_01253 9.8e-76 G Peptidase_C39 like family
HAFJMHLM_01254 9.4e-192 S Acyltransferase family
HAFJMHLM_01255 3.5e-116 L Transposase DDE domain
HAFJMHLM_01256 1.1e-102 L Transposase DDE domain
HAFJMHLM_01257 5.5e-225 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HAFJMHLM_01258 2.2e-151 dprA LU DNA protecting protein DprA
HAFJMHLM_01259 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HAFJMHLM_01260 1.1e-245 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HAFJMHLM_01261 2e-163 xerC D Phage integrase, N-terminal SAM-like domain
HAFJMHLM_01262 4e-90 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HAFJMHLM_01263 2.6e-242 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HAFJMHLM_01264 3.4e-174 lacX 5.1.3.3 G Aldose 1-epimerase
HAFJMHLM_01266 3.6e-249 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HAFJMHLM_01267 4e-223 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HAFJMHLM_01269 6.9e-156 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HAFJMHLM_01270 3.7e-194 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HAFJMHLM_01271 4.7e-41 ydiN G Major Facilitator Superfamily
HAFJMHLM_01272 1.3e-66 5.99.1.2 T diguanylate cyclase
HAFJMHLM_01273 4.9e-82 S ECF-type riboflavin transporter, S component
HAFJMHLM_01274 1.7e-257 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
HAFJMHLM_01275 8.2e-143 cbiQ P cobalt transport
HAFJMHLM_01276 0.0 ykoD P ABC transporter, ATP-binding protein
HAFJMHLM_01277 5.5e-98 S UPF0397 protein
HAFJMHLM_01278 2.7e-157 salL 2.5.1.63, 2.5.1.94 K S-adenosyl-l-methionine hydroxide adenosyltransferase
HAFJMHLM_01279 3.8e-241 cycA E Amino acid permease
HAFJMHLM_01280 0.0 S ABC-type transport system involved in multi-copper enzyme maturation permease component
HAFJMHLM_01281 1.2e-166 ytrB V ABC transporter
HAFJMHLM_01282 3.3e-59 ytrA K helix_turn_helix gluconate operon transcriptional repressor
HAFJMHLM_01288 1.1e-198 napA P Sodium/hydrogen exchanger family
HAFJMHLM_01289 0.0 cadA P P-type ATPase
HAFJMHLM_01290 1.3e-82 ykuL S (CBS) domain
HAFJMHLM_01291 2.1e-224 ywhK S Membrane
HAFJMHLM_01292 2.1e-07
HAFJMHLM_01294 2.4e-294 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HAFJMHLM_01295 3.7e-240 dltB M MBOAT, membrane-bound O-acyltransferase family
HAFJMHLM_01296 2e-36 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HAFJMHLM_01297 2.1e-238 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HAFJMHLM_01299 5.2e-63 S Iron-sulphur cluster biosynthesis
HAFJMHLM_01300 0.0 yhcA V ABC transporter, ATP-binding protein
HAFJMHLM_01301 2.1e-114 K Bacterial regulatory proteins, tetR family
HAFJMHLM_01303 1.3e-09 pipD M Peptidase family C69
HAFJMHLM_01304 6.9e-170 citR K Putative sugar-binding domain
HAFJMHLM_01305 8.9e-33 lysM M LysM domain
HAFJMHLM_01306 0.0 pepN 3.4.11.2 E aminopeptidase
HAFJMHLM_01307 2.9e-71 drgA C nitroreductase
HAFJMHLM_01309 3e-218 S Putative peptidoglycan binding domain
HAFJMHLM_01310 6.6e-116
HAFJMHLM_01311 7.9e-137 S Belongs to the UPF0246 family
HAFJMHLM_01312 2.9e-249 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
HAFJMHLM_01313 2.9e-82 ygfC K transcriptional regulator (TetR family)
HAFJMHLM_01314 5e-185 hrtB V ABC transporter permease
HAFJMHLM_01315 1.3e-117 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HAFJMHLM_01317 8.1e-224 amd 3.5.1.47 E Peptidase dimerisation domain
HAFJMHLM_01318 2.8e-222 pbuG S permease
HAFJMHLM_01319 7.5e-87 EGP Major facilitator Superfamily
HAFJMHLM_01320 2e-131 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HAFJMHLM_01321 6.2e-37 mutR K Helix-turn-helix XRE-family like proteins
HAFJMHLM_01322 1e-101 3.6.4.12 K Psort location Cytoplasmic, score 8.87
HAFJMHLM_01323 1.7e-09
HAFJMHLM_01324 2.3e-263 clcA P chloride
HAFJMHLM_01325 1.5e-95 msbA2 3.6.3.44 V ABC transporter
HAFJMHLM_01327 1.7e-64 O protein import
HAFJMHLM_01328 0.0 copB 3.6.3.4 P P-type ATPase
HAFJMHLM_01329 2.4e-58 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
HAFJMHLM_01330 9.3e-56 tnp2PF3 L Transposase DDE domain
HAFJMHLM_01331 5.2e-141 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HAFJMHLM_01332 4.2e-71 L DDE superfamily endonuclease
HAFJMHLM_01333 7.2e-98 L DDE superfamily endonuclease
HAFJMHLM_01334 5e-46 ypaA S membrane
HAFJMHLM_01335 2.8e-82 K AsnC family
HAFJMHLM_01336 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HAFJMHLM_01337 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HAFJMHLM_01338 6.7e-165 mleP3 S Membrane transport protein
HAFJMHLM_01339 3.5e-307 ybiT S ABC transporter, ATP-binding protein
HAFJMHLM_01340 9.8e-56
HAFJMHLM_01341 4.9e-213 mdtG EGP Major facilitator Superfamily
HAFJMHLM_01342 1.6e-118 ybhL S Belongs to the BI1 family
HAFJMHLM_01343 1.6e-140 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HAFJMHLM_01344 2.7e-279 pipD E Dipeptidase
HAFJMHLM_01345 1.9e-208 pepA E M42 glutamyl aminopeptidase
HAFJMHLM_01346 1.6e-100 S ABC-type cobalt transport system, permease component
HAFJMHLM_01348 4.5e-109 udk 2.7.1.48 F Zeta toxin
HAFJMHLM_01349 1.8e-116 udk 2.7.1.48 F Zeta toxin
HAFJMHLM_01350 3.6e-129 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HAFJMHLM_01351 1.5e-144 glnH ET ABC transporter substrate-binding protein
HAFJMHLM_01352 6e-109 gluC P ABC transporter permease
HAFJMHLM_01353 6.3e-109 glnP P ABC transporter permease
HAFJMHLM_01354 2.1e-149 glnH ET Bacterial periplasmic substrate-binding proteins
HAFJMHLM_01355 5.5e-278 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HAFJMHLM_01356 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HAFJMHLM_01357 5.1e-262 S Uncharacterized protein conserved in bacteria (DUF2252)
HAFJMHLM_01358 2.5e-18 S Protein of unknown function (DUF2974)
HAFJMHLM_01359 6.9e-62 S Protein of unknown function (DUF2974)
HAFJMHLM_01360 1.2e-36
HAFJMHLM_01361 8.6e-87
HAFJMHLM_01362 1.7e-157 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HAFJMHLM_01363 2.9e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HAFJMHLM_01364 6.1e-123 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HAFJMHLM_01365 2.8e-171 rihB 3.2.2.1 F Nucleoside
HAFJMHLM_01366 1.7e-128 gntR K UbiC transcription regulator-associated domain protein
HAFJMHLM_01367 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HAFJMHLM_01368 6e-21 3.4.22.70 M Sortase family
HAFJMHLM_01369 1.6e-241 yhdP S Transporter associated domain
HAFJMHLM_01370 1.6e-100 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HAFJMHLM_01371 4.3e-223 potE E amino acid
HAFJMHLM_01372 4.6e-123 lytC 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
HAFJMHLM_01373 2.1e-206 yfmL 3.6.4.13 L DEAD DEAH box helicase
HAFJMHLM_01374 3e-240 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HAFJMHLM_01376 9.6e-168 pfoS S Phosphotransferase system, EIIC
HAFJMHLM_01377 2.5e-231 pyrP F Permease
HAFJMHLM_01378 1.8e-226 ynbB 4.4.1.1 P aluminum resistance
HAFJMHLM_01379 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
HAFJMHLM_01381 2.5e-267 E Amino acid permease
HAFJMHLM_01382 6.5e-22
HAFJMHLM_01383 5.9e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HAFJMHLM_01384 4.9e-63 gtcA S Teichoic acid glycosylation protein
HAFJMHLM_01385 1.9e-77 fld C Flavodoxin
HAFJMHLM_01386 7.9e-162 map 3.4.11.18 E Methionine Aminopeptidase
HAFJMHLM_01387 5.7e-161 yihY S Belongs to the UPF0761 family
HAFJMHLM_01388 3.7e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HAFJMHLM_01389 9.7e-19
HAFJMHLM_01390 4.4e-180 D Alpha beta
HAFJMHLM_01391 3.8e-241 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HAFJMHLM_01392 1.8e-142 recX 2.4.1.337 GT4 S Regulatory protein RecX
HAFJMHLM_01393 4.5e-85
HAFJMHLM_01394 3.7e-71
HAFJMHLM_01395 1.1e-153 hlyX S Transporter associated domain
HAFJMHLM_01396 3.6e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HAFJMHLM_01397 3.5e-25
HAFJMHLM_01398 1.4e-279 mco Q Multicopper oxidase
HAFJMHLM_01399 8e-157 cjaA ET ABC transporter substrate-binding protein
HAFJMHLM_01400 5.9e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HAFJMHLM_01401 3.7e-101 P ABC transporter permease
HAFJMHLM_01402 1.7e-111 papP P ABC transporter, permease protein
HAFJMHLM_01403 4.3e-21 adhR K helix_turn_helix, mercury resistance
HAFJMHLM_01404 1e-15 adhR K helix_turn_helix, mercury resistance
HAFJMHLM_01405 9.5e-40 L Transposase and inactivated derivatives, IS30 family
HAFJMHLM_01406 9.3e-118 L Transposase and inactivated derivatives, IS30 family
HAFJMHLM_01407 2e-97 3.6.1.55, 3.6.1.67 F NUDIX domain
HAFJMHLM_01408 1e-196 folP 2.5.1.15 H dihydropteroate synthase
HAFJMHLM_01409 1.7e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HAFJMHLM_01410 2.1e-199 folE 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 F GTP cyclohydrolase 1
HAFJMHLM_01411 1.5e-56 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HAFJMHLM_01412 3.9e-51 magIII L Base excision DNA repair protein, HhH-GPD family
HAFJMHLM_01413 7.2e-16
HAFJMHLM_01414 2.1e-41 S SLAP domain
HAFJMHLM_01415 4.4e-21 XK27_01125 L IS66 Orf2 like protein
HAFJMHLM_01416 8.8e-18
HAFJMHLM_01417 8.6e-205 G Major Facilitator Superfamily
HAFJMHLM_01418 1.9e-145
HAFJMHLM_01419 2e-132 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HAFJMHLM_01420 2.8e-299 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HAFJMHLM_01421 7.4e-289 ytgP S Polysaccharide biosynthesis protein
HAFJMHLM_01422 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HAFJMHLM_01423 1e-64 3.6.1.27 I Acid phosphatase homologues
HAFJMHLM_01424 2.9e-35 3.6.1.27 I Acid phosphatase homologues
HAFJMHLM_01425 2.1e-258 mdr EGP Sugar (and other) transporter
HAFJMHLM_01426 1.5e-214 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HAFJMHLM_01434 2.8e-42 XK27_09445 S Domain of unknown function (DUF1827)
HAFJMHLM_01435 0.0 clpE O Belongs to the ClpA ClpB family
HAFJMHLM_01436 1.2e-10
HAFJMHLM_01437 6.1e-39 ptsH G phosphocarrier protein HPR
HAFJMHLM_01438 6.5e-299 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HAFJMHLM_01439 5e-69 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HAFJMHLM_01440 2.4e-133 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HAFJMHLM_01441 1.1e-161 coiA 3.6.4.12 S Competence protein
HAFJMHLM_01442 3.6e-109 yjbH Q Thioredoxin
HAFJMHLM_01443 6.3e-108 yjbK S CYTH
HAFJMHLM_01444 9e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
HAFJMHLM_01445 5.7e-149 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HAFJMHLM_01446 4.2e-172 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HAFJMHLM_01447 3.3e-150 S Protein of unknown function (DUF3298)
HAFJMHLM_01448 3.6e-97 K Sigma-70 region 2
HAFJMHLM_01449 2e-223 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HAFJMHLM_01450 1.5e-91 J Acetyltransferase (GNAT) domain
HAFJMHLM_01451 8.3e-105 yjbF S SNARE associated Golgi protein
HAFJMHLM_01452 2.4e-147 I alpha/beta hydrolase fold
HAFJMHLM_01453 4.5e-155 hipB K Helix-turn-helix
HAFJMHLM_01454 8.6e-95 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
HAFJMHLM_01455 2.1e-128 yfeJ 6.3.5.2 F glutamine amidotransferase
HAFJMHLM_01456 2.7e-231 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HAFJMHLM_01457 3.5e-159
HAFJMHLM_01459 3.9e-226 mmgC 1.3.8.1 I Acyl-CoA dehydrogenase, C-terminal domain
HAFJMHLM_01460 6.3e-285 V ABC-type multidrug transport system, ATPase and permease components
HAFJMHLM_01461 9.4e-281 V ABC-type multidrug transport system, ATPase and permease components
HAFJMHLM_01462 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HAFJMHLM_01463 1.6e-126
HAFJMHLM_01464 2e-39 cpsY K Transcriptional regulator, LysR family
HAFJMHLM_01465 2.9e-187 2.1.1.14 E methionine synthase, vitamin-B12 independent
HAFJMHLM_01467 4.4e-87 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
HAFJMHLM_01468 7.8e-79 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
HAFJMHLM_01469 3e-170 glfT1 1.1.1.133 S Glycosyltransferase like family 2
HAFJMHLM_01470 8.6e-212 M Glycosyl transferases group 1
HAFJMHLM_01471 2.3e-147 M Domain of unknown function (DUF4422)
HAFJMHLM_01472 6.6e-08 wzy S EpsG family
HAFJMHLM_01473 2.4e-259 epsIIL S Membrane protein involved in the export of O-antigen and teichoic acid
HAFJMHLM_01474 6.2e-176 M LicD family
HAFJMHLM_01475 2.2e-84 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
HAFJMHLM_01476 8.2e-29
HAFJMHLM_01477 0.0 L Helicase C-terminal domain protein
HAFJMHLM_01478 5.8e-92 T integral membrane protein
HAFJMHLM_01479 9.5e-117 L Putative transposase DNA-binding domain
HAFJMHLM_01480 8.9e-81 S YcxB-like protein
HAFJMHLM_01481 7.7e-68 K Transcriptional regulator
HAFJMHLM_01482 7.1e-16 qorB 1.6.5.2 GM epimerase
HAFJMHLM_01483 5.1e-63 qorB 1.6.5.2 GM NmrA-like family
HAFJMHLM_01484 1.3e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HAFJMHLM_01485 1e-06
HAFJMHLM_01486 3.4e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HAFJMHLM_01487 1.4e-09 ibrB K ParB-like nuclease domain
HAFJMHLM_01489 9.1e-32 K acetyltransferase
HAFJMHLM_01490 3.4e-30 S Alpha beta hydrolase
HAFJMHLM_01491 1e-33 S Alpha beta hydrolase
HAFJMHLM_01492 3.8e-170 dap2 3.4.19.1 E Prolyl oligopeptidase family
HAFJMHLM_01493 4.1e-37 ybjQ S Belongs to the UPF0145 family
HAFJMHLM_01494 8.3e-201 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HAFJMHLM_01495 1.4e-23
HAFJMHLM_01496 4.8e-56 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
HAFJMHLM_01497 5.8e-44 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HAFJMHLM_01498 3.1e-23 ansA 3.5.1.1 EJ L-asparaginase
HAFJMHLM_01499 4.4e-29 K Transcriptional regulator
HAFJMHLM_01500 2.9e-87 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HAFJMHLM_01501 1.9e-55 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HAFJMHLM_01502 4e-47 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HAFJMHLM_01503 3.2e-155 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HAFJMHLM_01504 1.3e-159 penP 3.5.2.6 V beta-lactamase
HAFJMHLM_01505 7.4e-35 F Belongs to the purine-cytosine permease (2.A.39) family
HAFJMHLM_01506 7.8e-114 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HAFJMHLM_01507 6.2e-123 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HAFJMHLM_01508 2e-72 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
HAFJMHLM_01509 6.5e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HAFJMHLM_01510 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HAFJMHLM_01511 1.5e-143 EGP Major facilitator Superfamily
HAFJMHLM_01512 7.9e-11 K Transcriptional regulator
HAFJMHLM_01514 1.1e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HAFJMHLM_01515 4.1e-29 L IS66 Orf2 like protein
HAFJMHLM_01516 8e-09 L Transposase, IS605 OrfB family
HAFJMHLM_01517 7.4e-49 S Sel1-like repeats.
HAFJMHLM_01518 2.4e-178 S Uncharacterized protein conserved in bacteria (DUF2325)
HAFJMHLM_01519 1.4e-204 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HAFJMHLM_01520 4.7e-199 xerS L Belongs to the 'phage' integrase family
HAFJMHLM_01522 5.8e-146 D CobQ CobB MinD ParA nucleotide binding domain protein
HAFJMHLM_01523 1.3e-243 isp2 L Transposase
HAFJMHLM_01524 4.5e-236 G Bacterial extracellular solute-binding protein
HAFJMHLM_01525 8.7e-256 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
HAFJMHLM_01526 1.2e-146 gtsC P Binding-protein-dependent transport system inner membrane component
HAFJMHLM_01527 1.4e-156 gtsB P ABC-type sugar transport systems, permease components
HAFJMHLM_01528 2.4e-198 malK P ATPases associated with a variety of cellular activities
HAFJMHLM_01529 6.2e-206 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HAFJMHLM_01530 3.3e-178 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HAFJMHLM_01531 2.1e-88 C Nitroreductase family
HAFJMHLM_01532 9.1e-43 XK27_06785 V ABC transporter, ATP-binding protein
HAFJMHLM_01533 2.2e-31 XK27_06780 V ABC transporter permease
HAFJMHLM_01534 8.7e-113 3.1.3.73 G phosphoglycerate mutase
HAFJMHLM_01535 2.5e-106 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HAFJMHLM_01536 2e-09 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HAFJMHLM_01537 2.5e-164 EG EamA-like transporter family
HAFJMHLM_01538 2.1e-154
HAFJMHLM_01539 2.6e-56 degV S EDD domain protein, DegV family
HAFJMHLM_01540 1.6e-70 degV S EDD domain protein, DegV family
HAFJMHLM_01541 3.5e-305 FbpA K Fibronectin-binding protein
HAFJMHLM_01542 6.4e-246 XK27_08635 S UPF0210 protein
HAFJMHLM_01543 3.1e-41 gcvR T Belongs to the UPF0237 family
HAFJMHLM_01544 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
HAFJMHLM_01545 6.3e-196 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HAFJMHLM_01546 4.1e-167 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HAFJMHLM_01547 8.4e-65 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HAFJMHLM_01548 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HAFJMHLM_01549 4.8e-55
HAFJMHLM_01550 2.4e-80 XK27_01810 S Calcineurin-like phosphoesterase
HAFJMHLM_01551 1.8e-41 XK27_01810 S Calcineurin-like phosphoesterase
HAFJMHLM_01552 4e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HAFJMHLM_01553 1.1e-56 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HAFJMHLM_01554 6.2e-102 ypsA S Belongs to the UPF0398 family
HAFJMHLM_01555 9.5e-115 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HAFJMHLM_01556 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HAFJMHLM_01557 0.0 dap2 3.4.19.1 E Prolyl oligopeptidase family
HAFJMHLM_01558 2.7e-188 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HAFJMHLM_01559 2e-86 I alpha/beta hydrolase fold
HAFJMHLM_01560 3.7e-148 S Sucrose-6F-phosphate phosphohydrolase
HAFJMHLM_01561 2.1e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HAFJMHLM_01562 3.7e-114 dnaD L DnaD domain protein
HAFJMHLM_01563 9.3e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HAFJMHLM_01564 9.8e-59 ypmB S Protein conserved in bacteria
HAFJMHLM_01565 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HAFJMHLM_01566 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HAFJMHLM_01567 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HAFJMHLM_01568 4.3e-161 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
HAFJMHLM_01569 1.2e-172 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HAFJMHLM_01570 3e-201 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HAFJMHLM_01571 5.5e-189 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HAFJMHLM_01572 8.9e-170 ppaC 3.6.1.1 C inorganic pyrophosphatase
HAFJMHLM_01573 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HAFJMHLM_01574 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HAFJMHLM_01575 1.8e-97 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HAFJMHLM_01576 3.5e-120 S CAAX protease self-immunity
HAFJMHLM_01577 1.3e-196 S DUF218 domain
HAFJMHLM_01578 3.2e-195 tcsA S ABC transporter substrate-binding protein PnrA-like
HAFJMHLM_01581 9.7e-69 S Domain of unknown function (DUF4352)
HAFJMHLM_01582 4.4e-192 tcsA S ABC transporter substrate-binding protein PnrA-like
HAFJMHLM_01583 1.1e-10 tlpA2 L Transposase IS200 like
HAFJMHLM_01584 7e-31 tlpA2 L Transposase IS200 like
HAFJMHLM_01585 2.1e-51 I alpha/beta hydrolase fold
HAFJMHLM_01586 1.1e-128 yibF S overlaps another CDS with the same product name
HAFJMHLM_01587 1.4e-182 yibE S overlaps another CDS with the same product name
HAFJMHLM_01588 1.7e-39
HAFJMHLM_01589 7.6e-205 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HAFJMHLM_01590 5.1e-192 S Cysteine-rich secretory protein family
HAFJMHLM_01591 4.1e-113 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
HAFJMHLM_01592 7.3e-186 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HAFJMHLM_01593 6.4e-84 1.1.3.15 C FAD linked oxidases, C-terminal domain
HAFJMHLM_01594 3.9e-51 1.1.3.15 C FAD linked oxidases, C-terminal domain
HAFJMHLM_01595 1.4e-47 C FAD linked oxidase domain protein
HAFJMHLM_01596 4.2e-74 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HAFJMHLM_01597 4e-116 metQ_4 P Belongs to the nlpA lipoprotein family
HAFJMHLM_01598 4.2e-91 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HAFJMHLM_01599 1.9e-149 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HAFJMHLM_01601 0.0 G Belongs to the glycosyl hydrolase 31 family
HAFJMHLM_01602 1.5e-101 malG P ABC transporter permease
HAFJMHLM_01603 8.2e-48 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HAFJMHLM_01604 5.5e-11 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
HAFJMHLM_01605 9.5e-48 L Transposase, IS605 OrfB family
HAFJMHLM_01606 2.9e-130 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HAFJMHLM_01607 1.2e-242 tetL EGP Major Facilitator Superfamily
HAFJMHLM_01608 3.4e-121 L Replication protein
HAFJMHLM_01609 1.7e-168 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HAFJMHLM_01610 6.2e-16 F DNA/RNA non-specific endonuclease
HAFJMHLM_01611 4.6e-33 F DNA/RNA non-specific endonuclease
HAFJMHLM_01612 7.7e-61
HAFJMHLM_01614 1.4e-54 K sequence-specific DNA binding
HAFJMHLM_01615 3e-179 gpsA 1.1.1.94 I Rossmann-like domain
HAFJMHLM_01616 8.3e-30 P metal ion transport
HAFJMHLM_01617 9.8e-57 K LysR family
HAFJMHLM_01618 4.2e-63 K LysR family
HAFJMHLM_01619 2.8e-22 L MULE transposase domain
HAFJMHLM_01620 5e-16
HAFJMHLM_01621 8.7e-11 S Transglycosylase associated protein
HAFJMHLM_01622 3.8e-22 S Asp23 family, cell envelope-related function
HAFJMHLM_01623 1.9e-75 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HAFJMHLM_01624 1.8e-28 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HAFJMHLM_01625 3.5e-121 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HAFJMHLM_01632 9.3e-119 S ECF-type riboflavin transporter, S component
HAFJMHLM_01633 0.0 ykoD_2 S AAA domain, putative AbiEii toxin, Type IV TA system
HAFJMHLM_01634 2.6e-150 P ABC-type cobalt transport system permease component CbiQ and related transporters
HAFJMHLM_01635 3.2e-14 S Iron-sulfur cluster assembly protein
HAFJMHLM_01636 8.2e-45 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HAFJMHLM_01637 4.9e-240 asnB 6.3.5.4 E Aluminium induced protein
HAFJMHLM_01638 7.7e-56 asnB 6.3.5.4 E Aluminium induced protein
HAFJMHLM_01644 2.5e-86 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HAFJMHLM_01645 7.6e-218 argH 2.3.1.1, 4.3.2.1 E argininosuccinate lyase
HAFJMHLM_01646 3.6e-219 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HAFJMHLM_01647 7.9e-110 lysR7 K LysR substrate binding domain
HAFJMHLM_01648 1.9e-84 lysR7 K Bacterial regulatory helix-turn-helix protein, lysR family
HAFJMHLM_01651 2.2e-69
HAFJMHLM_01652 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HAFJMHLM_01653 2.6e-10
HAFJMHLM_01654 2.8e-84 K DNA-binding transcription factor activity
HAFJMHLM_01655 1.7e-165 K LysR substrate binding domain
HAFJMHLM_01656 0.0 S Bacterial membrane protein YfhO
HAFJMHLM_01657 1.3e-224 S Tetratricopeptide repeat protein
HAFJMHLM_01658 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HAFJMHLM_01659 5.9e-244 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HAFJMHLM_01660 3.2e-204 rpsA 1.17.7.4 J Ribosomal protein S1
HAFJMHLM_01661 4.7e-106 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HAFJMHLM_01663 1.6e-115 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HAFJMHLM_01664 3.5e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HAFJMHLM_01665 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HAFJMHLM_01666 6.2e-126 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HAFJMHLM_01667 2.4e-59 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HAFJMHLM_01668 1e-162 xerD D recombinase XerD
HAFJMHLM_01669 3.4e-163 cvfB S S1 domain
HAFJMHLM_01670 3.6e-62 I Acyltransferase family
HAFJMHLM_01671 4e-31 ssuB P ATPases associated with a variety of cellular activities
HAFJMHLM_01672 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HAFJMHLM_01673 1.7e-179 pfkA 2.7.1.11, 2.7.1.90 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HAFJMHLM_01674 0.0 dnaE 2.7.7.7 L DNA polymerase
HAFJMHLM_01675 1.8e-27 S Protein of unknown function (DUF2929)
HAFJMHLM_01676 2e-31 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HAFJMHLM_01677 1.1e-172 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HAFJMHLM_01678 3.6e-76 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HAFJMHLM_01679 8e-30 gmuR K UbiC transcription regulator-associated domain protein
HAFJMHLM_01680 4.4e-95 ywlG S Belongs to the UPF0340 family
HAFJMHLM_01681 3.8e-66
HAFJMHLM_01682 0.0 L SNF2 family N-terminal domain
HAFJMHLM_01683 1.9e-302 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HAFJMHLM_01684 1e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HAFJMHLM_01685 5.5e-136 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HAFJMHLM_01686 1.4e-175 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HAFJMHLM_01687 0.0 oatA I Acyltransferase
HAFJMHLM_01688 4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HAFJMHLM_01689 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HAFJMHLM_01690 7.1e-183 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
HAFJMHLM_01691 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HAFJMHLM_01692 3.9e-173 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HAFJMHLM_01693 3.1e-184 S Amidohydrolase
HAFJMHLM_01694 4.7e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HAFJMHLM_01695 3.8e-76 argR K Regulates arginine biosynthesis genes
HAFJMHLM_01696 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HAFJMHLM_01697 5e-165 K LysR substrate binding domain
HAFJMHLM_01698 4.2e-220 EK Aminotransferase, class I
HAFJMHLM_01699 2.6e-70 E Methionine synthase
HAFJMHLM_01700 6.8e-67 L Transposase and inactivated derivatives
HAFJMHLM_01701 2.1e-88 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HAFJMHLM_01702 1.7e-41 yrzL S Belongs to the UPF0297 family
HAFJMHLM_01703 1.5e-31 flgM KNU Negative regulator of flagellin synthesis
HAFJMHLM_01704 2.2e-41 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HAFJMHLM_01705 4e-78 L COG2963 Transposase and inactivated derivatives
HAFJMHLM_01706 0.0 pacL 3.6.3.8 P P-type ATPase
HAFJMHLM_01707 1.6e-149 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HAFJMHLM_01708 1.3e-133 M Glycosyltransferase sugar-binding region containing DXD motif
HAFJMHLM_01709 7e-198 csaB M Glycosyl transferases group 1
HAFJMHLM_01710 9e-133 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HAFJMHLM_01711 6.6e-257 epsU S Polysaccharide biosynthesis protein
HAFJMHLM_01712 5.5e-222 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HAFJMHLM_01713 6.1e-123 gntR1 K UTRA
HAFJMHLM_01714 3.5e-194
HAFJMHLM_01715 2.7e-213
HAFJMHLM_01716 3.2e-246 oppA2 E ABC transporter, substratebinding protein
HAFJMHLM_01720 9.8e-165 pfoS S Phosphotransferase system, EIIC
HAFJMHLM_01721 3e-223 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HAFJMHLM_01724 2.2e-87 S Phosphatidylethanolamine-binding protein
HAFJMHLM_01725 1.1e-32 EGP Major facilitator Superfamily
HAFJMHLM_01726 1.1e-38 EGP Major facilitator Superfamily
HAFJMHLM_01727 6.4e-116 XK27_07525 3.6.1.55 F NUDIX domain
HAFJMHLM_01728 1.3e-246 oppA E ABC transporter, substratebinding protein
HAFJMHLM_01729 5.9e-34
HAFJMHLM_01730 1.1e-18
HAFJMHLM_01731 1.1e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HAFJMHLM_01732 4.2e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HAFJMHLM_01733 1.7e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HAFJMHLM_01734 6.7e-142 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HAFJMHLM_01735 3.7e-162 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HAFJMHLM_01736 5.8e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HAFJMHLM_01737 1.3e-61 rplQ J Ribosomal protein L17
HAFJMHLM_01738 5.6e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HAFJMHLM_01739 1.2e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HAFJMHLM_01740 5.5e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HAFJMHLM_01741 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HAFJMHLM_01742 8.6e-119 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HAFJMHLM_01743 1.1e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HAFJMHLM_01744 2.6e-71 rplO J Binds to the 23S rRNA
HAFJMHLM_01745 1.3e-24 rpmD J Ribosomal protein L30
HAFJMHLM_01746 6.3e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HAFJMHLM_01747 6.3e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HAFJMHLM_01748 1e-90 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HAFJMHLM_01749 5.1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HAFJMHLM_01750 2.7e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HAFJMHLM_01751 2.2e-32 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HAFJMHLM_01752 2.8e-58 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HAFJMHLM_01753 3.8e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HAFJMHLM_01754 1.8e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
HAFJMHLM_01755 1.9e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HAFJMHLM_01756 2.7e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HAFJMHLM_01757 8.9e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HAFJMHLM_01758 4.5e-45 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HAFJMHLM_01759 2e-152 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HAFJMHLM_01760 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HAFJMHLM_01761 1.3e-105 rplD J Forms part of the polypeptide exit tunnel
HAFJMHLM_01762 5.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HAFJMHLM_01763 9.8e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HAFJMHLM_01764 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HAFJMHLM_01765 4.6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HAFJMHLM_01766 1e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HAFJMHLM_01767 2.6e-48 S hydrolase
HAFJMHLM_01768 4.6e-13 S hydrolase
HAFJMHLM_01769 1.4e-08 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HAFJMHLM_01770 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HAFJMHLM_01771 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HAFJMHLM_01773 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HAFJMHLM_01774 1.1e-80 yebR 1.8.4.14 T GAF domain-containing protein
HAFJMHLM_01778 1.6e-106 XK27_00160 S Domain of unknown function (DUF5052)
HAFJMHLM_01780 2.2e-44 ydjN U Involved in the tonB-independent uptake of proteins
HAFJMHLM_01782 6e-144 yliE T Putative diguanylate phosphodiesterase
HAFJMHLM_01783 2.3e-62 yliE T domain protein
HAFJMHLM_01784 5.5e-183 arbY M Glycosyl transferase family 8
HAFJMHLM_01785 1.5e-253 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HAFJMHLM_01786 3.4e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HAFJMHLM_01787 8.8e-47
HAFJMHLM_01788 1.1e-264 pepC 3.4.22.40 E Peptidase C1-like family
HAFJMHLM_01789 5.5e-45 S LlaJI restriction endonuclease
HAFJMHLM_01790 4.2e-69 V AAA domain (dynein-related subfamily)
HAFJMHLM_01791 6.7e-135 ddeI 2.1.1.37 H PFAM C-5 cytosine-specific DNA methylase
HAFJMHLM_01792 2.8e-113 nlaXM 2.1.1.37 H PFAM C-5 cytosine-specific DNA methylase
HAFJMHLM_01793 1.5e-16 K Cro/C1-type HTH DNA-binding domain
HAFJMHLM_01794 6.3e-122 2.1.1.37 H C-5 cytosine-specific DNA methylase
HAFJMHLM_01795 6.4e-19 S NgoFVII restriction endonuclease
HAFJMHLM_01796 2.8e-67
HAFJMHLM_01797 1.4e-45
HAFJMHLM_01798 3.2e-129
HAFJMHLM_01799 1.1e-199 S GTP binding
HAFJMHLM_01800 2e-09 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
HAFJMHLM_01801 1.2e-41 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
HAFJMHLM_01802 3e-34 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
HAFJMHLM_01803 2.2e-10 5.2.1.8 O Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
HAFJMHLM_01804 4.8e-24 5.2.1.8 O Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
HAFJMHLM_01805 1.4e-178 S AAA domain
HAFJMHLM_01806 1.7e-76 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HAFJMHLM_01807 1.2e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HAFJMHLM_01808 5.8e-28
HAFJMHLM_01809 3.7e-27
HAFJMHLM_01810 7e-124 pgm3 G Belongs to the phosphoglycerate mutase family
HAFJMHLM_01811 4.5e-116 S membrane transporter protein
HAFJMHLM_01812 1e-107 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HAFJMHLM_01813 8.4e-93 wecD K Acetyltransferase (GNAT) family
HAFJMHLM_01814 3.6e-191 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HAFJMHLM_01815 1.1e-106 3.5.2.6 V Beta-lactamase
HAFJMHLM_01816 1.8e-136 ybbH_2 K Helix-turn-helix domain, rpiR family
HAFJMHLM_01817 7.2e-272 pepV 3.5.1.18 E dipeptidase PepV
HAFJMHLM_01818 8.7e-47 cycA E Amino acid permease
HAFJMHLM_01819 1.3e-73 S Plasmid pRiA4b ORF-3-like protein
HAFJMHLM_01821 2.5e-55 cycA E Amino acid permease
HAFJMHLM_01822 7.5e-94 S Domain of unknown function (DUF4867)
HAFJMHLM_01823 3.5e-100 rpiB 2.1.1.222, 2.1.1.64, 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
HAFJMHLM_01824 2e-71 lacA 5.3.1.26 G Ribose/Galactose Isomerase
HAFJMHLM_01825 8e-116 lacR K DeoR C terminal sensor domain
HAFJMHLM_01826 5.7e-110 yqhA G Aldose 1-epimerase
HAFJMHLM_01827 9.7e-124 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 H pfkB family carbohydrate kinase
HAFJMHLM_01828 3.7e-174 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
HAFJMHLM_01829 8.8e-27
HAFJMHLM_01830 2e-258 gatC G PTS system sugar-specific permease component
HAFJMHLM_01831 3.1e-50 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
HAFJMHLM_01832 6.7e-76 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HAFJMHLM_01833 4.6e-63 XK27_01040
HAFJMHLM_01834 2.9e-260 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
HAFJMHLM_01835 3.8e-259 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
HAFJMHLM_01836 1.8e-84 lacT K CAT RNA binding domain
HAFJMHLM_01837 5.4e-43 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
HAFJMHLM_01838 5e-246 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
HAFJMHLM_01839 1.2e-192 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HAFJMHLM_01840 2.3e-228 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HAFJMHLM_01841 1.1e-135 D nuclear chromosome segregation
HAFJMHLM_01842 2.5e-75 M LysM domain protein
HAFJMHLM_01846 7.5e-155 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HAFJMHLM_01847 3.9e-276 thrC 4.2.3.1 E Threonine synthase
HAFJMHLM_01851 2e-97 K Acetyltransferase (GNAT) domain
HAFJMHLM_01852 2.1e-22
HAFJMHLM_01853 1.7e-155 scrR K Transcriptional regulator, LacI family
HAFJMHLM_01854 1.2e-237 scrB 3.2.1.26 GH32 G invertase
HAFJMHLM_01855 1.3e-303 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
HAFJMHLM_01856 1.5e-197 pfkA 2.7.1.11, 2.7.1.90 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HAFJMHLM_01857 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HAFJMHLM_01858 3.6e-172 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
HAFJMHLM_01859 4.4e-18 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
HAFJMHLM_01860 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
HAFJMHLM_01861 2.2e-276 E Amino acid permease
HAFJMHLM_01862 4.2e-28 L Transposase and inactivated derivatives, IS30 family
HAFJMHLM_01864 4.8e-68 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
HAFJMHLM_01865 1.2e-121 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
HAFJMHLM_01866 1.2e-214 oxlT P Major Facilitator Superfamily
HAFJMHLM_01867 4.3e-31 K sequence-specific DNA binding
HAFJMHLM_01868 0.0 recQ1 L Helicase conserved C-terminal domain
HAFJMHLM_01869 1e-187 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HAFJMHLM_01870 4.1e-158 3.5.2.6 M NlpC/P60 family
HAFJMHLM_01871 3.4e-242 cycA E Amino acid permease
HAFJMHLM_01873 2.4e-62 manO S Domain of unknown function (DUF956)
HAFJMHLM_01874 1.2e-163 manN G system, mannose fructose sorbose family IID component
HAFJMHLM_01875 1.3e-132 manY G PTS system
HAFJMHLM_01876 4.1e-181 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HAFJMHLM_01878 4.7e-244 nhaC C Na H antiporter NhaC
HAFJMHLM_01879 8.7e-33 citM C Citrate transporter
HAFJMHLM_01880 4.9e-182 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HAFJMHLM_01881 1.1e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HAFJMHLM_01882 6.5e-154 ycsE S Sucrose-6F-phosphate phosphohydrolase
HAFJMHLM_01883 1.3e-102
HAFJMHLM_01884 5.1e-23 3.2.2.20 K acetyltransferase
HAFJMHLM_01885 4.5e-62 3.2.2.20 K acetyltransferase
HAFJMHLM_01886 6e-140 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HAFJMHLM_01887 3.3e-225 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HAFJMHLM_01888 5.5e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HAFJMHLM_01889 7.8e-208 cggR K Putative sugar-binding domain
HAFJMHLM_01891 3.4e-135 XK27_08845 S ABC transporter, ATP-binding protein
HAFJMHLM_01892 7.8e-147 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HAFJMHLM_01893 4.8e-142 ABC-SBP S ABC transporter
HAFJMHLM_01894 8.2e-238
HAFJMHLM_01895 1.2e-100 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HAFJMHLM_01896 5.4e-167 whiA K May be required for sporulation
HAFJMHLM_01897 7.2e-189 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HAFJMHLM_01898 2e-163 rapZ S Displays ATPase and GTPase activities
HAFJMHLM_01899 8.9e-158 dmpA 3.4.11.19 EQ Peptidase family S58
HAFJMHLM_01900 5e-145 E D-aminopeptidase
HAFJMHLM_01901 1.9e-87 S Short repeat of unknown function (DUF308)
HAFJMHLM_01902 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HAFJMHLM_01903 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HAFJMHLM_01904 3.2e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HAFJMHLM_01905 2.3e-187 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HAFJMHLM_01906 2.5e-155 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HAFJMHLM_01907 2.4e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HAFJMHLM_01908 2.6e-30
HAFJMHLM_01909 2.3e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HAFJMHLM_01910 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HAFJMHLM_01911 3.9e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HAFJMHLM_01912 3.8e-117 comFC S Competence protein
HAFJMHLM_01913 2.8e-238 comFA L Helicase C-terminal domain protein
HAFJMHLM_01914 2.6e-115 yvyE 3.4.13.9 S YigZ family
HAFJMHLM_01915 1.2e-211 tagO 2.7.8.33, 2.7.8.35 M transferase
HAFJMHLM_01916 1.2e-214 rny S Endoribonuclease that initiates mRNA decay
HAFJMHLM_01917 8.6e-196 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HAFJMHLM_01918 2.7e-97 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HAFJMHLM_01919 8.6e-98 ymfM S Helix-turn-helix domain
HAFJMHLM_01920 1.2e-132 IQ Enoyl-(Acyl carrier protein) reductase
HAFJMHLM_01921 1.2e-233 S Peptidase M16
HAFJMHLM_01922 3.2e-228 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
HAFJMHLM_01923 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HAFJMHLM_01924 1.9e-68 WQ51_03320 S Protein of unknown function (DUF1149)
HAFJMHLM_01925 8.7e-104 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HAFJMHLM_01926 3.3e-177 yubA S AI-2E family transporter
HAFJMHLM_01927 1.1e-62 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HAFJMHLM_01928 2.7e-196 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HAFJMHLM_01929 3.7e-143 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HAFJMHLM_01930 6.3e-22
HAFJMHLM_01931 2.6e-13 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HAFJMHLM_01932 9.7e-48 yutD S protein conserved in bacteria

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)