ORF_ID e_value Gene_name EC_number CAZy COGs Description
HEOGLLMH_00001 9e-14 yajQ S Belongs to the UPF0234 family
HEOGLLMH_00002 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HEOGLLMH_00003 1.1e-80 yjcF S Acetyltransferase (GNAT) domain
HEOGLLMH_00004 1.7e-71 mcbG S Pentapeptide repeats (9 copies)
HEOGLLMH_00005 1.1e-89 yisT S DinB family
HEOGLLMH_00006 5.9e-160 yisR K Transcriptional regulator
HEOGLLMH_00007 6.1e-244 yisQ V Mate efflux family protein
HEOGLLMH_00008 2e-132 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
HEOGLLMH_00009 8.2e-88 asnO 6.3.5.4 E Asparagine synthase
HEOGLLMH_00010 4.1e-222 asnO 6.3.5.4 E Asparagine synthase
HEOGLLMH_00011 3.1e-98 yisN S Protein of unknown function (DUF2777)
HEOGLLMH_00012 1.1e-59 yisL S UPF0344 protein
HEOGLLMH_00013 1.7e-170 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HEOGLLMH_00015 8.4e-34 gerPA S Spore germination protein
HEOGLLMH_00016 3.1e-25 gerPB S cell differentiation
HEOGLLMH_00017 1.4e-62 gerPC S Spore germination protein
HEOGLLMH_00018 3.1e-23 gerPD S Spore germination protein
HEOGLLMH_00019 3.9e-22 gerPE S Spore germination protein GerPE
HEOGLLMH_00020 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
HEOGLLMH_00021 8.6e-48 yisB V COG1403 Restriction endonuclease
HEOGLLMH_00022 3.2e-131 sbcC L COG0419 ATPase involved in DNA repair
HEOGLLMH_00023 7e-222 sbcC L COG0419 ATPase involved in DNA repair
HEOGLLMH_00024 3.9e-86 sbcC L COG0419 ATPase involved in DNA repair
HEOGLLMH_00025 8.7e-66 sbcC L COG0419 ATPase involved in DNA repair
HEOGLLMH_00026 9.5e-113 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HEOGLLMH_00027 1.6e-21 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HEOGLLMH_00028 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HEOGLLMH_00029 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
HEOGLLMH_00030 4.3e-124 ydfS S Protein of unknown function (DUF421)
HEOGLLMH_00031 9.7e-94 yhjR S Rubrerythrin
HEOGLLMH_00032 1e-108 K QacR-like protein, C-terminal region
HEOGLLMH_00033 2.5e-209 blt EGP Major facilitator Superfamily
HEOGLLMH_00034 4.3e-182 abrB S membrane
HEOGLLMH_00035 5.8e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
HEOGLLMH_00036 1.6e-274 yhjG CH FAD binding domain
HEOGLLMH_00037 9.2e-92 sipV 3.4.21.89 U Belongs to the peptidase S26 family
HEOGLLMH_00038 2.6e-109 yhjE S SNARE associated Golgi protein
HEOGLLMH_00039 1.7e-60 yhjD
HEOGLLMH_00040 6.9e-27 yhjC S Protein of unknown function (DUF3311)
HEOGLLMH_00041 4.2e-267 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEOGLLMH_00042 1.2e-46 S Belongs to the UPF0145 family
HEOGLLMH_00043 1.6e-42 yhjA S Excalibur calcium-binding domain
HEOGLLMH_00044 3e-125 yrpD S Domain of unknown function, YrpD
HEOGLLMH_00045 1.3e-168 els S Acetyltransferase, GNAT family
HEOGLLMH_00046 5.4e-68 mepB S MepB protein
HEOGLLMH_00047 1.5e-31 frataxin S Domain of unknown function (DU1801)
HEOGLLMH_00048 3.9e-68 frataxin S Domain of unknown function (DU1801)
HEOGLLMH_00049 4.2e-109 comK K Competence transcription factor
HEOGLLMH_00050 1.3e-32 yhzC S IDEAL
HEOGLLMH_00051 3.8e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEOGLLMH_00052 1.2e-111 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
HEOGLLMH_00053 9.2e-152 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
HEOGLLMH_00054 1.6e-176 hemAT NT chemotaxis protein
HEOGLLMH_00055 1e-88 bioY S BioY family
HEOGLLMH_00056 6.1e-207 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HEOGLLMH_00057 1.8e-201 vraB 2.3.1.9 I Belongs to the thiolase family
HEOGLLMH_00058 3.1e-104 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HEOGLLMH_00059 1.7e-123 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HEOGLLMH_00060 1.9e-22 aprE 3.4.21.62 O Belongs to the peptidase S8 family
HEOGLLMH_00061 9.1e-170 aprE 3.4.21.62 O Belongs to the peptidase S8 family
HEOGLLMH_00062 1.1e-172 yhfN 3.4.24.84 O Peptidase M48
HEOGLLMH_00063 2.9e-39 yhfN 3.4.24.84 O Peptidase M48
HEOGLLMH_00064 2.4e-15 yhfM
HEOGLLMH_00065 1e-34 yhfM
HEOGLLMH_00066 1.5e-266 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HEOGLLMH_00067 2.9e-111 yhfK GM NmrA-like family
HEOGLLMH_00068 3.5e-188 lplJ 6.3.1.20 H Lipoate-protein ligase
HEOGLLMH_00069 1.1e-138 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HEOGLLMH_00070 7.9e-11 yhfH S YhfH-like protein
HEOGLLMH_00071 3.4e-228 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEOGLLMH_00072 3e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
HEOGLLMH_00074 3.3e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HEOGLLMH_00075 3.2e-277 yhgE S YhgE Pip N-terminal domain protein
HEOGLLMH_00076 3.2e-101 yhgD K Transcriptional regulator
HEOGLLMH_00077 8.6e-136 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HEOGLLMH_00078 8.7e-122 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HEOGLLMH_00079 1.4e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HEOGLLMH_00080 8.6e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HEOGLLMH_00081 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HEOGLLMH_00082 2.7e-88 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HEOGLLMH_00083 1.4e-243 yhfA C membrane
HEOGLLMH_00084 1.6e-224 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HEOGLLMH_00085 5.6e-124 ecsC S EcsC protein family
HEOGLLMH_00086 1.5e-220 ecsB U ABC transporter
HEOGLLMH_00087 1.1e-135 ecsA V transporter (ATP-binding protein)
HEOGLLMH_00088 2.4e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HEOGLLMH_00089 3.8e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HEOGLLMH_00090 1.4e-76 trpP S Tryptophan transporter TrpP
HEOGLLMH_00091 2e-17
HEOGLLMH_00092 2.3e-08 yhaH S YtxH-like protein
HEOGLLMH_00093 1.4e-102 hpr K Negative regulator of protease production and sporulation
HEOGLLMH_00094 9.9e-55 yhaI S Protein of unknown function (DUF1878)
HEOGLLMH_00095 7e-95 yhaK S Putative zincin peptidase
HEOGLLMH_00096 3.3e-30
HEOGLLMH_00097 6.3e-122 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HEOGLLMH_00098 1.6e-32 yhaL S Sporulation protein YhaL
HEOGLLMH_00099 1.3e-176 yhaM L Shows a 3'-5' exoribonuclease activity
HEOGLLMH_00100 0.0 yhaN L AAA domain
HEOGLLMH_00101 4.5e-238 yhaO L DNA repair exonuclease
HEOGLLMH_00102 8e-206 yhaP CP COG1668 ABC-type Na efflux pump, permease component
HEOGLLMH_00103 7.5e-103 yhaQ S ABC transporter, ATP-binding protein
HEOGLLMH_00104 3.5e-52 yhaQ S ABC transporter, ATP-binding protein
HEOGLLMH_00105 7.3e-15 S YhzD-like protein
HEOGLLMH_00106 1.3e-79 yhaR 5.3.3.18 I enoyl-CoA hydratase
HEOGLLMH_00107 1.5e-08 yhaR 5.3.3.18 I enoyl-CoA hydratase
HEOGLLMH_00108 2.5e-21 yhaR 5.3.3.18 I enoyl-CoA hydratase
HEOGLLMH_00109 3.9e-87 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
HEOGLLMH_00110 8.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
HEOGLLMH_00111 5.8e-252 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
HEOGLLMH_00112 1.3e-292 hemZ H coproporphyrinogen III oxidase
HEOGLLMH_00113 1.9e-158 yhaX S haloacid dehalogenase-like hydrolase
HEOGLLMH_00114 2.5e-156 yhaZ L DNA alkylation repair enzyme
HEOGLLMH_00115 3.8e-19 yhaZ L DNA alkylation repair enzyme
HEOGLLMH_00116 4.4e-53 yheA S Belongs to the UPF0342 family
HEOGLLMH_00117 8.6e-52 yheB S Belongs to the UPF0754 family
HEOGLLMH_00118 7.2e-105 yheB S Belongs to the UPF0754 family
HEOGLLMH_00119 4.1e-211 yheC HJ YheC/D like ATP-grasp
HEOGLLMH_00120 4.6e-129 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
HEOGLLMH_00121 4.4e-100 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
HEOGLLMH_00122 1.2e-28 yheE S Family of unknown function (DUF5342)
HEOGLLMH_00123 5.8e-29 sspB S spore protein
HEOGLLMH_00125 8.1e-111 yheG GM NAD(P)H-binding
HEOGLLMH_00126 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
HEOGLLMH_00127 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
HEOGLLMH_00129 6.2e-85 T universal stress protein
HEOGLLMH_00130 1.5e-90 ymcC S Membrane
HEOGLLMH_00131 3.6e-85 pksA K Transcriptional regulator
HEOGLLMH_00132 1.8e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HEOGLLMH_00133 2.7e-157 yheN G deacetylase
HEOGLLMH_00134 4.5e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HEOGLLMH_00135 1.5e-64 yhdY M Mechanosensitive ion channel
HEOGLLMH_00136 1.4e-109 yhdY M Mechanosensitive ion channel
HEOGLLMH_00138 6.9e-130 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HEOGLLMH_00139 1.3e-61 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEOGLLMH_00140 1.9e-51 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEOGLLMH_00141 8.4e-257 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
HEOGLLMH_00142 1.9e-228 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HEOGLLMH_00143 1.1e-225 yhdR 2.6.1.1 E Aminotransferase
HEOGLLMH_00144 4.3e-71 cueR K transcriptional
HEOGLLMH_00145 1.6e-241 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HEOGLLMH_00146 5.1e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HEOGLLMH_00147 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
HEOGLLMH_00148 8.8e-84 yhdL S Sigma factor regulator N-terminal
HEOGLLMH_00149 3.5e-40 yhdL S Sigma factor regulator N-terminal
HEOGLLMH_00150 1.4e-22 yhdL S Sigma factor regulator N-terminal
HEOGLLMH_00151 8.1e-45 yhdK S Sigma-M inhibitor protein
HEOGLLMH_00152 2e-199 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HEOGLLMH_00153 1e-51 yhdG E amino acid
HEOGLLMH_00154 1.5e-119 yhdG E amino acid
HEOGLLMH_00155 3e-11 yhdG E amino acid
HEOGLLMH_00156 7.8e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEOGLLMH_00157 7e-206 citA 2.3.3.1 C Belongs to the citrate synthase family
HEOGLLMH_00158 8.6e-08 citR K Transcriptional regulator
HEOGLLMH_00159 8.6e-119 citR K Transcriptional regulator
HEOGLLMH_00160 5.2e-79 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HEOGLLMH_00162 2e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HEOGLLMH_00163 1.8e-270 ycgB S Stage V sporulation protein R
HEOGLLMH_00164 7.7e-256 ygxB M Conserved TM helix
HEOGLLMH_00165 5.6e-74 nsrR K Transcriptional regulator
HEOGLLMH_00166 5.9e-213 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HEOGLLMH_00167 1.5e-52 yhdC S Protein of unknown function (DUF3889)
HEOGLLMH_00168 2.5e-39 yhdB S YhdB-like protein
HEOGLLMH_00169 1.1e-89 azr 1.7.1.6 S NADPH-dependent FMN reductase
HEOGLLMH_00170 1.5e-112 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEOGLLMH_00171 9.9e-203 yhcY 2.7.13.3 T Histidine kinase
HEOGLLMH_00172 1.1e-253 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HEOGLLMH_00173 1.9e-41 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HEOGLLMH_00174 4.4e-241 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HEOGLLMH_00175 3.6e-41 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HEOGLLMH_00176 1.9e-294 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HEOGLLMH_00177 6.3e-143 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
HEOGLLMH_00178 1.5e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HEOGLLMH_00179 1.2e-260 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEOGLLMH_00180 3.8e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HEOGLLMH_00181 4.9e-125 yhcW 5.4.2.6 S hydrolase
HEOGLLMH_00182 7.6e-68 yhcV S COG0517 FOG CBS domain
HEOGLLMH_00183 2.5e-31 yhcU S Family of unknown function (DUF5365)
HEOGLLMH_00184 4.6e-17 yhcU S Family of unknown function (DUF5365)
HEOGLLMH_00185 1.1e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HEOGLLMH_00186 1.8e-107 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HEOGLLMH_00187 0.0 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
HEOGLLMH_00188 1.5e-115 yhcQ M Spore coat protein
HEOGLLMH_00189 2e-154 yhcP
HEOGLLMH_00190 5.7e-84 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HEOGLLMH_00191 7e-56 yhcM
HEOGLLMH_00192 1.7e-38 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEOGLLMH_00193 5.6e-154 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEOGLLMH_00194 3.9e-194 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
HEOGLLMH_00195 2.3e-54 metQ M Belongs to the nlpA lipoprotein family
HEOGLLMH_00196 2.9e-79 metQ M Belongs to the nlpA lipoprotein family
HEOGLLMH_00197 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
HEOGLLMH_00198 3.3e-164 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HEOGLLMH_00199 4.1e-167 yhcH V ABC transporter, ATP-binding protein
HEOGLLMH_00200 3e-125 yhcG V ABC transporter, ATP-binding protein
HEOGLLMH_00201 7.3e-62 yhcF K Transcriptional regulator
HEOGLLMH_00202 9.6e-53
HEOGLLMH_00203 1.4e-54 yhcC
HEOGLLMH_00204 1.4e-98 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
HEOGLLMH_00205 6.4e-285 yhcA EGP Major facilitator Superfamily
HEOGLLMH_00206 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
HEOGLLMH_00207 4.6e-74 yhbI K DNA-binding transcription factor activity
HEOGLLMH_00208 1.2e-82 yhbH S Belongs to the UPF0229 family
HEOGLLMH_00209 1.8e-122 yhbH S Belongs to the UPF0229 family
HEOGLLMH_00210 0.0 prkA T Ser protein kinase
HEOGLLMH_00212 1e-64 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
HEOGLLMH_00213 8.6e-64 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
HEOGLLMH_00214 1e-108 yhbD K Protein of unknown function (DUF4004)
HEOGLLMH_00215 2e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HEOGLLMH_00216 4.8e-176 yhbB S Putative amidase domain
HEOGLLMH_00217 1.2e-160 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HEOGLLMH_00218 6.5e-51 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HEOGLLMH_00219 1.6e-52 yhzB S B3/4 domain
HEOGLLMH_00220 1.2e-48 yhzB S B3/4 domain
HEOGLLMH_00222 1.6e-79 ygaO
HEOGLLMH_00223 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HEOGLLMH_00224 5e-215 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
HEOGLLMH_00225 4e-145 ssuC P ABC transporter (permease)
HEOGLLMH_00226 1.1e-181 ssuA M Sulfonate ABC transporter
HEOGLLMH_00227 1.1e-138 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HEOGLLMH_00228 3.4e-185 S Amidohydrolase
HEOGLLMH_00229 7.8e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HEOGLLMH_00230 1.6e-134 oppF3 E Belongs to the ABC transporter superfamily
HEOGLLMH_00231 2.2e-134 oppD3 P Belongs to the ABC transporter superfamily
HEOGLLMH_00232 1.1e-127 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEOGLLMH_00233 5.8e-148 appB P Binding-protein-dependent transport system inner membrane component
HEOGLLMH_00234 9.5e-231 oppA5 E PFAM extracellular solute-binding protein family 5
HEOGLLMH_00236 1.7e-266 ygaK C Berberine and berberine like
HEOGLLMH_00237 1.1e-272 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HEOGLLMH_00238 1.5e-54 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HEOGLLMH_00239 1.7e-133 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
HEOGLLMH_00240 6.7e-287 C Na+/H+ antiporter family
HEOGLLMH_00244 1.6e-08
HEOGLLMH_00252 7.8e-08
HEOGLLMH_00257 5.4e-162 ygxA S Nucleotidyltransferase-like
HEOGLLMH_00258 1.5e-56 ygzB S UPF0295 protein
HEOGLLMH_00259 1.8e-80 perR P Belongs to the Fur family
HEOGLLMH_00260 3.1e-86 bcp 1.11.1.15 O Peroxiredoxin
HEOGLLMH_00261 3.1e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HEOGLLMH_00262 2.7e-178 ygaE S Membrane
HEOGLLMH_00263 2.2e-244 ygaD V ABC transporter
HEOGLLMH_00264 1.2e-34 ygaD V ABC transporter
HEOGLLMH_00265 2.2e-104 ygaC J Belongs to the UPF0374 family
HEOGLLMH_00266 1.5e-37 ygaB S YgaB-like protein
HEOGLLMH_00268 5.8e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEOGLLMH_00269 8.2e-37 yfhS
HEOGLLMH_00270 1.5e-205 mutY L A G-specific
HEOGLLMH_00271 1.4e-184 yfhP S membrane-bound metal-dependent
HEOGLLMH_00272 0.0 yfhO S Bacterial membrane protein YfhO
HEOGLLMH_00273 9.4e-181 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HEOGLLMH_00274 1.4e-169 yfhM S Alpha/beta hydrolase family
HEOGLLMH_00275 3.3e-34 yfhL S SdpI/YhfL protein family
HEOGLLMH_00276 3.5e-94 batE T Bacterial SH3 domain homologues
HEOGLLMH_00277 2.2e-44 yfhJ S WVELL protein
HEOGLLMH_00278 1.4e-167 mpr 3.4.21.19 M Belongs to the peptidase S1B family
HEOGLLMH_00280 4.7e-132 yfhI EGP Major facilitator Superfamily
HEOGLLMH_00281 5.3e-53 yfhI EGP Major facilitator Superfamily
HEOGLLMH_00282 9.7e-52 yfhH S Protein of unknown function (DUF1811)
HEOGLLMH_00283 3e-142 recX 2.4.1.337 GT4 S Modulates RecA activity
HEOGLLMH_00284 3.6e-168 yfhF S nucleoside-diphosphate sugar epimerase
HEOGLLMH_00286 2.1e-25 yfhD S YfhD-like protein
HEOGLLMH_00287 3.3e-106 yfhC C nitroreductase
HEOGLLMH_00288 3.9e-167 yfhB 5.3.3.17 S PhzF family
HEOGLLMH_00289 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HEOGLLMH_00290 5.6e-83 yfiV K transcriptional
HEOGLLMH_00291 2.3e-290 yfiU EGP Major facilitator Superfamily
HEOGLLMH_00292 1.8e-98 yfiT S Belongs to the metal hydrolase YfiT family
HEOGLLMH_00293 7.6e-45 yrdF K ribonuclease inhibitor
HEOGLLMH_00294 8.7e-237 2.7.9.2 GT phosphoenolpyruvate synthase
HEOGLLMH_00295 1.5e-217 2.7.9.2 GT phosphoenolpyruvate synthase
HEOGLLMH_00296 3.1e-182 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HEOGLLMH_00297 3.3e-79 1.6.5.2 S NADPH-dependent FMN reductase
HEOGLLMH_00298 3.4e-22 1.6.5.2 S NADPH-dependent FMN reductase
HEOGLLMH_00299 1.7e-96 padR K transcriptional
HEOGLLMH_00300 5.3e-170 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HEOGLLMH_00301 1.1e-161 yfiE 1.13.11.2 S glyoxalase
HEOGLLMH_00302 7e-63 mhqP S DoxX
HEOGLLMH_00303 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
HEOGLLMH_00304 9.6e-311 yfiB3 V ABC transporter
HEOGLLMH_00305 0.0 yobO M COG5434 Endopolygalacturonase
HEOGLLMH_00306 1.9e-52 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HEOGLLMH_00307 2.9e-152 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HEOGLLMH_00308 5.6e-138 glvR F Helix-turn-helix domain, rpiR family
HEOGLLMH_00309 4.5e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HEOGLLMH_00310 4.2e-15 sspH S Belongs to the SspH family
HEOGLLMH_00311 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
HEOGLLMH_00312 1.5e-152 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HEOGLLMH_00313 1.1e-92 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HEOGLLMH_00314 4.7e-216 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HEOGLLMH_00315 2.5e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HEOGLLMH_00316 2.4e-189 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HEOGLLMH_00317 1.3e-95 yfjM S Psort location Cytoplasmic, score
HEOGLLMH_00318 3e-193 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEOGLLMH_00319 8.7e-38 S YfzA-like protein
HEOGLLMH_00320 6.2e-268 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEOGLLMH_00321 5.2e-164 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HEOGLLMH_00322 3.8e-184 corA P Mediates influx of magnesium ions
HEOGLLMH_00323 7.1e-33
HEOGLLMH_00324 4.7e-149 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HEOGLLMH_00325 9e-155 pdaA G deacetylase
HEOGLLMH_00326 4.9e-27 yfjT
HEOGLLMH_00327 1.5e-219 yfkA S YfkB-like domain
HEOGLLMH_00328 1.4e-146 yfkC M Mechanosensitive ion channel
HEOGLLMH_00329 1.3e-185 cax P COG0387 Ca2 H antiporter
HEOGLLMH_00330 4.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
HEOGLLMH_00331 2.5e-07
HEOGLLMH_00332 1.5e-144 yihY S Belongs to the UPF0761 family
HEOGLLMH_00333 2e-52 yfkI S gas vesicle protein
HEOGLLMH_00334 4.1e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HEOGLLMH_00335 2.7e-29 yfkK S Belongs to the UPF0435 family
HEOGLLMH_00336 1.3e-192 ydiM EGP Major facilitator Superfamily
HEOGLLMH_00337 1.8e-136 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HEOGLLMH_00338 3.1e-164 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HEOGLLMH_00339 3e-187 K helix_turn _helix lactose operon repressor
HEOGLLMH_00340 3.1e-62 yfkM 1.11.1.6, 3.5.1.124 S protease
HEOGLLMH_00341 4.4e-141 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
HEOGLLMH_00342 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
HEOGLLMH_00343 2e-200 yibE S YibE/F-like protein
HEOGLLMH_00344 4.2e-125 yibF S YibE/F-like protein
HEOGLLMH_00345 1.2e-123 yfkO C nitroreductase
HEOGLLMH_00346 9.9e-129 treR K transcriptional
HEOGLLMH_00347 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HEOGLLMH_00348 7.3e-240 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HEOGLLMH_00349 1.2e-39 ydgB S Spore germination protein gerPA/gerPF
HEOGLLMH_00350 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
HEOGLLMH_00351 8.3e-79 cotP O Belongs to the small heat shock protein (HSP20) family
HEOGLLMH_00352 1.7e-63 yhdN S Domain of unknown function (DUF1992)
HEOGLLMH_00353 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HEOGLLMH_00354 2.2e-73 yfmQ S Uncharacterised protein from bacillus cereus group
HEOGLLMH_00355 8.7e-246 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HEOGLLMH_00356 7.2e-138 map 3.4.11.18 E Methionine aminopeptidase
HEOGLLMH_00357 3.1e-50 yflH S Protein of unknown function (DUF3243)
HEOGLLMH_00358 7e-19 yflI
HEOGLLMH_00359 4.4e-123 yflK S protein conserved in bacteria
HEOGLLMH_00360 1.7e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HEOGLLMH_00361 1.4e-219 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HEOGLLMH_00362 8.7e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
HEOGLLMH_00363 3.9e-41 citM C Citrate transporter
HEOGLLMH_00364 5.8e-167 citM C Citrate transporter
HEOGLLMH_00365 8.3e-179 yflP S Tripartite tricarboxylate transporter family receptor
HEOGLLMH_00366 4.7e-120 citT T response regulator
HEOGLLMH_00367 1.3e-253 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HEOGLLMH_00368 9.9e-86 M1-820 Q Collagen triple helix repeat (20 copies)
HEOGLLMH_00369 2.3e-133 Q calcium- and calmodulin-responsive adenylate cyclase activity
HEOGLLMH_00370 1.1e-110 Q PFAM Collagen triple helix
HEOGLLMH_00371 1.2e-33 Q PFAM Collagen triple helix
HEOGLLMH_00372 7.5e-74 yflS P Sodium:sulfate symporter transmembrane region
HEOGLLMH_00373 3.4e-150 yflS P Sodium:sulfate symporter transmembrane region
HEOGLLMH_00374 2.6e-241 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
HEOGLLMH_00375 1.3e-57 yflT S Heat induced stress protein YflT
HEOGLLMH_00376 1.5e-24 S Protein of unknown function (DUF3212)
HEOGLLMH_00377 2.9e-129 yfmJ S N-terminal domain of oxidoreductase
HEOGLLMH_00378 8.7e-40 yfmJ S N-terminal domain of oxidoreductase
HEOGLLMH_00379 1.8e-64 yfmK 2.3.1.128 K acetyltransferase
HEOGLLMH_00380 2.1e-205 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
HEOGLLMH_00381 2.2e-122 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HEOGLLMH_00382 3.3e-47 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HEOGLLMH_00383 3.4e-94 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HEOGLLMH_00384 2.1e-208 yfmO EGP Major facilitator Superfamily
HEOGLLMH_00385 9e-69 yfmP K transcriptional
HEOGLLMH_00386 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HEOGLLMH_00387 5.5e-208 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HEOGLLMH_00388 5.2e-167 IQ Enoyl-(Acyl carrier protein) reductase
HEOGLLMH_00389 9.8e-115 yfmS NT chemotaxis protein
HEOGLLMH_00390 2e-277 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HEOGLLMH_00391 1e-246 yfnA E amino acid
HEOGLLMH_00392 3.6e-219 fsr P COG0477 Permeases of the major facilitator superfamily
HEOGLLMH_00393 5.6e-188 yfnD M Nucleotide-diphospho-sugar transferase
HEOGLLMH_00394 8.6e-223 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
HEOGLLMH_00395 3.2e-180 yfnF M Nucleotide-diphospho-sugar transferase
HEOGLLMH_00396 1.7e-168 yfnG 4.2.1.45 M dehydratase
HEOGLLMH_00397 3.9e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
HEOGLLMH_00398 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HEOGLLMH_00400 2.7e-249 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HEOGLLMH_00401 2.1e-296 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HEOGLLMH_00402 4.4e-36 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HEOGLLMH_00403 7.5e-197 yetN S Protein of unknown function (DUF3900)
HEOGLLMH_00404 2.8e-210 yetM CH FAD binding domain
HEOGLLMH_00405 5.5e-89 yetL K helix_turn_helix multiple antibiotic resistance protein
HEOGLLMH_00406 8.2e-106 yetJ S Belongs to the BI1 family
HEOGLLMH_00407 1.8e-55 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
HEOGLLMH_00408 1.2e-22 yezD S Uncharacterized small protein (DUF2292)
HEOGLLMH_00409 5.2e-119 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HEOGLLMH_00410 8.2e-27 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HEOGLLMH_00411 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEOGLLMH_00412 5.7e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HEOGLLMH_00413 8.7e-122 yetF S membrane
HEOGLLMH_00415 7.5e-97 yesJ K Acetyltransferase (GNAT) family
HEOGLLMH_00416 4.5e-91 cotJC P Spore Coat
HEOGLLMH_00417 6.2e-45 cotJB S CotJB protein
HEOGLLMH_00419 9.4e-127 yeeN K transcriptional regulatory protein
HEOGLLMH_00420 1.8e-71 yobL S Bacterial EndoU nuclease
HEOGLLMH_00421 2.2e-130 yobL S Bacterial EndoU nuclease
HEOGLLMH_00422 3.9e-42 S Immunity protein 22
HEOGLLMH_00423 1.4e-97 yobL L nucleic acid phosphodiester bond hydrolysis
HEOGLLMH_00424 1e-60 S Protein of unknown function, DUF600
HEOGLLMH_00425 1.1e-77 S Protein of unknown function, DUF600
HEOGLLMH_00426 1.7e-79 S Protein of unknown function, DUF600
HEOGLLMH_00427 3.3e-54 S Protein of unknown function, DUF600
HEOGLLMH_00428 4.3e-48 S Protein of unknown function, DUF600
HEOGLLMH_00429 8.7e-49 S Protein of unknown function, DUF600
HEOGLLMH_00430 2.5e-53 S Protein of unknown function, DUF600
HEOGLLMH_00431 3.8e-138 cylB V ABC-2 type transporter
HEOGLLMH_00432 3.6e-158 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
HEOGLLMH_00433 9.5e-13
HEOGLLMH_00434 3.5e-247 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEOGLLMH_00435 1.6e-168 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HEOGLLMH_00436 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HEOGLLMH_00437 5.3e-153 yerO K Transcriptional regulator
HEOGLLMH_00438 5.2e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEOGLLMH_00439 1.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HEOGLLMH_00440 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEOGLLMH_00441 3.7e-263 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEOGLLMH_00442 1.4e-114 sapB S MgtC SapB transporter
HEOGLLMH_00443 1.6e-82 yerI S homoserine kinase type II (protein kinase fold)
HEOGLLMH_00444 3.5e-211 camS S COG4851 Protein involved in sex pheromone biosynthesis
HEOGLLMH_00445 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HEOGLLMH_00446 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HEOGLLMH_00447 9e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HEOGLLMH_00448 5e-20 yerD 1.4.7.1 E Belongs to the glutamate synthase family
HEOGLLMH_00449 5.8e-252 yerD 1.4.7.1 E Belongs to the glutamate synthase family
HEOGLLMH_00450 2.4e-50 yerC S protein conserved in bacteria
HEOGLLMH_00451 1.2e-191 yerB S Protein of unknown function (DUF3048) C-terminal domain
HEOGLLMH_00452 5.8e-296 yerA 3.5.4.2 F adenine deaminase
HEOGLLMH_00453 3.1e-17 yerA 3.5.4.2 F adenine deaminase
HEOGLLMH_00454 2e-25 S Protein of unknown function (DUF2892)
HEOGLLMH_00455 3.7e-235 purD 6.3.4.13 F Belongs to the GARS family
HEOGLLMH_00456 1.2e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HEOGLLMH_00457 8.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HEOGLLMH_00458 2.7e-183 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HEOGLLMH_00459 8e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HEOGLLMH_00460 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEOGLLMH_00461 1.9e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEOGLLMH_00462 1.4e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEOGLLMH_00463 1.6e-82 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HEOGLLMH_00464 7.7e-39 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HEOGLLMH_00465 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HEOGLLMH_00466 7.1e-220 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HEOGLLMH_00467 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HEOGLLMH_00468 3.6e-17 yebG S NETI protein
HEOGLLMH_00469 1.6e-20 yebE S UPF0316 protein
HEOGLLMH_00470 2.3e-53 yebE S UPF0316 protein
HEOGLLMH_00472 4.6e-30 yebC M Membrane
HEOGLLMH_00473 4.3e-87 yebC M Membrane
HEOGLLMH_00474 6.2e-209 pbuG S permease
HEOGLLMH_00475 2.5e-248 S Domain of unknown function (DUF4179)
HEOGLLMH_00476 1.2e-91 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HEOGLLMH_00477 1.2e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HEOGLLMH_00478 0.0 yebA E COG1305 Transglutaminase-like enzymes
HEOGLLMH_00479 1.3e-33 yebA E COG1305 Transglutaminase-like enzymes
HEOGLLMH_00480 2.1e-205 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HEOGLLMH_00481 1.3e-176 yeaC S COG0714 MoxR-like ATPases
HEOGLLMH_00482 7.1e-153 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEOGLLMH_00483 5.6e-245 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
HEOGLLMH_00484 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
HEOGLLMH_00485 8.6e-35 ydjO S Cold-inducible protein YdjO
HEOGLLMH_00487 1e-134 ydjN U Involved in the tonB-independent uptake of proteins
HEOGLLMH_00488 1.4e-62 ydjM M Lytic transglycolase
HEOGLLMH_00489 8.9e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
HEOGLLMH_00490 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HEOGLLMH_00491 1.2e-147 rsiV S Protein of unknown function (DUF3298)
HEOGLLMH_00492 4.1e-19 yrhL I Acyltransferase family
HEOGLLMH_00493 5.6e-298 yrhL I Acyltransferase family
HEOGLLMH_00494 3.2e-157 ydjI S virion core protein (lumpy skin disease virus)
HEOGLLMH_00495 3.1e-105 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
HEOGLLMH_00496 8.8e-179 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HEOGLLMH_00497 5.1e-114 pspA KT Phage shock protein A
HEOGLLMH_00498 5.2e-28 yjdJ S Domain of unknown function (DUF4306)
HEOGLLMH_00499 5.8e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
HEOGLLMH_00500 5.9e-118 gutA G MFS/sugar transport protein
HEOGLLMH_00501 2.1e-120 gutA G MFS/sugar transport protein
HEOGLLMH_00502 3.8e-201 gutB 1.1.1.14 E Dehydrogenase
HEOGLLMH_00503 9.2e-292 K NB-ARC domain
HEOGLLMH_00504 1.6e-149 K NB-ARC domain
HEOGLLMH_00505 8.3e-47 S DNA-sulfur modification-associated
HEOGLLMH_00506 4.4e-27 L DNA-sulfur modification-associated
HEOGLLMH_00507 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HEOGLLMH_00508 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HEOGLLMH_00509 7.4e-22 ydiL S CAAX protease self-immunity
HEOGLLMH_00510 1.6e-80 ydiL S CAAX protease self-immunity
HEOGLLMH_00511 1.7e-27 ydiK S Domain of unknown function (DUF4305)
HEOGLLMH_00512 2e-104 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HEOGLLMH_00513 6.3e-09 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HEOGLLMH_00514 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HEOGLLMH_00515 3e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HEOGLLMH_00516 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HEOGLLMH_00517 0.0 ydiF S ABC transporter
HEOGLLMH_00518 1.4e-147 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HEOGLLMH_00519 2.2e-81 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HEOGLLMH_00520 1.3e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
HEOGLLMH_00521 4.1e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
HEOGLLMH_00522 2e-91 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HEOGLLMH_00523 3e-63 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HEOGLLMH_00525 7.8e-08
HEOGLLMH_00526 3.4e-39 S COG NOG14552 non supervised orthologous group
HEOGLLMH_00529 3.7e-252 iolT EGP Major facilitator Superfamily
HEOGLLMH_00530 4e-184 yhfP 1.1.1.1 C Quinone oxidoreductase
HEOGLLMH_00531 6.4e-84 yndB S Activator of Hsp90 ATPase homolog 1-like protein
HEOGLLMH_00532 3.2e-166 ydhU P Catalase
HEOGLLMH_00533 9.3e-297 yveA E amino acid
HEOGLLMH_00534 5.3e-104 yvdT K Transcriptional regulator
HEOGLLMH_00535 2.3e-51 ykkC P Small Multidrug Resistance protein
HEOGLLMH_00536 7.7e-49 sugE P Small Multidrug Resistance protein
HEOGLLMH_00537 2.4e-215 yeaN P COG2807 Cyanate permease
HEOGLLMH_00538 2.6e-118 K FCD
HEOGLLMH_00539 1.9e-132 ydhQ K UTRA
HEOGLLMH_00540 1.2e-195 pbuE EGP Major facilitator Superfamily
HEOGLLMH_00541 2.5e-98 ydhK M Protein of unknown function (DUF1541)
HEOGLLMH_00543 7.7e-263 pbpE V Beta-lactamase
HEOGLLMH_00546 1.4e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HEOGLLMH_00547 1e-105 ydhC K FCD
HEOGLLMH_00548 1.5e-51 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
HEOGLLMH_00549 1.1e-98 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
HEOGLLMH_00550 2.8e-87 ycgJ_1 Q ubiE/COQ5 methyltransferase family
HEOGLLMH_00551 1.3e-113 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
HEOGLLMH_00552 3.6e-73 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HEOGLLMH_00553 5.7e-152 bltR K helix_turn_helix, mercury resistance
HEOGLLMH_00554 2.6e-82 bltD 2.3.1.57 K FR47-like protein
HEOGLLMH_00555 1.3e-123 ydhB S membrane transporter protein
HEOGLLMH_00556 2.7e-157 K Helix-turn-helix XRE-family like proteins
HEOGLLMH_00557 2.8e-227 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HEOGLLMH_00558 7.9e-211 tcaB EGP Major facilitator Superfamily
HEOGLLMH_00559 3e-196 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
HEOGLLMH_00560 7.2e-150 S Uncharacterized protein conserved in bacteria (DUF2179)
HEOGLLMH_00561 1.9e-100 ynaD J Acetyltransferase (GNAT) domain
HEOGLLMH_00562 5.4e-119 expZ S ABC transporter
HEOGLLMH_00563 3e-26 expZ S ABC transporter
HEOGLLMH_00564 2.1e-79 expZ S ABC transporter
HEOGLLMH_00565 3.2e-124 puuD S Peptidase C26
HEOGLLMH_00566 0.0 ydfJ S drug exporters of the RND superfamily
HEOGLLMH_00567 1.2e-109 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEOGLLMH_00568 4.9e-219 ydfH 2.7.13.3 T Histidine kinase
HEOGLLMH_00569 2.2e-35 yraG
HEOGLLMH_00570 2.2e-63 yraF M Spore coat protein
HEOGLLMH_00571 6.1e-221 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HEOGLLMH_00572 1.4e-24 yraE
HEOGLLMH_00573 9.5e-49 yraD M Spore coat protein
HEOGLLMH_00574 3e-251 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEOGLLMH_00575 7.4e-158 ydeK EG -transporter
HEOGLLMH_00576 1.3e-102 ydeS K Transcriptional regulator
HEOGLLMH_00577 2.4e-104 ydeR EGP Major facilitator Superfamily
HEOGLLMH_00579 1.6e-114 paiB K Transcriptional regulator
HEOGLLMH_00580 1.4e-264 K helix_turn_helix gluconate operon transcriptional repressor
HEOGLLMH_00581 3.1e-229 mleN_2 C antiporter
HEOGLLMH_00582 3.6e-67 yraB K helix_turn_helix, mercury resistance
HEOGLLMH_00583 3.8e-201 adhA 1.1.1.1 C alcohol dehydrogenase
HEOGLLMH_00584 1.5e-167 S Sodium Bile acid symporter family
HEOGLLMH_00585 2e-51 ydeH
HEOGLLMH_00586 7.7e-197 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
HEOGLLMH_00588 1.5e-149 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
HEOGLLMH_00589 2.4e-86 ykkA S Protein of unknown function (DUF664)
HEOGLLMH_00590 2.8e-99 yrkC G Cupin domain
HEOGLLMH_00592 2e-112 trkA P Oxidoreductase
HEOGLLMH_00593 4.9e-168 czcD P COG1230 Co Zn Cd efflux system component
HEOGLLMH_00594 2.1e-33 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEOGLLMH_00595 1.3e-267 ygaK C COG0277 FAD FMN-containing dehydrogenases
HEOGLLMH_00598 9.2e-62 G Cupin domain
HEOGLLMH_00599 1.7e-84 S DinB superfamily
HEOGLLMH_00600 2.5e-183 S Patatin-like phospholipase
HEOGLLMH_00601 3.9e-224 ybfB G COG0477 Permeases of the major facilitator superfamily
HEOGLLMH_00602 2.1e-47 ybfA 3.4.15.5 K FR47-like protein
HEOGLLMH_00603 4e-105 ybfA 3.4.15.5 K FR47-like protein
HEOGLLMH_00604 4.9e-51 K Transcriptional regulator PadR-like family
HEOGLLMH_00605 1.2e-103 S Protein of unknown function (DUF2812)
HEOGLLMH_00606 3.1e-108 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HEOGLLMH_00607 3.3e-117 yrkJ S membrane transporter protein
HEOGLLMH_00608 5.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
HEOGLLMH_00609 3e-202 yrkH P Rhodanese Homology Domain
HEOGLLMH_00610 2.7e-100 yrkF OP Belongs to the sulfur carrier protein TusA family
HEOGLLMH_00611 5.6e-59 P Rhodanese Homology Domain
HEOGLLMH_00612 9.5e-83 yrkE O DsrE/DsrF/DrsH-like family
HEOGLLMH_00613 9.2e-40 yrkD S protein conserved in bacteria
HEOGLLMH_00614 1.4e-78 carD K Transcription factor
HEOGLLMH_00615 1.4e-30 cspL K Cold shock
HEOGLLMH_00616 6.5e-75 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HEOGLLMH_00617 4.2e-112 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HEOGLLMH_00618 2e-137 EG EamA-like transporter family
HEOGLLMH_00619 2.1e-78 gntR9 K GntR family transcriptional regulator
HEOGLLMH_00620 1.7e-90 gntR9 K GntR family transcriptional regulator
HEOGLLMH_00622 7.1e-207 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HEOGLLMH_00623 5e-137 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HEOGLLMH_00624 7.3e-28 Q ubiE/COQ5 methyltransferase family
HEOGLLMH_00625 1.2e-48 yxxF EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HEOGLLMH_00626 1.6e-51 yxxF EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HEOGLLMH_00627 3.5e-51 ywnB S NAD(P)H-binding
HEOGLLMH_00628 4.4e-15 ywnB S NAD(P)H-binding
HEOGLLMH_00629 2.2e-73 ywnA K Transcriptional regulator
HEOGLLMH_00631 3.2e-64 yyaQ S YjbR
HEOGLLMH_00632 1e-72 maoC I N-terminal half of MaoC dehydratase
HEOGLLMH_00633 1e-69 lrpA K transcriptional
HEOGLLMH_00634 1.1e-98 yddR S Zn-dependent hydrolases of the beta-lactamase fold
HEOGLLMH_00635 6.5e-72 S SnoaL-like polyketide cyclase
HEOGLLMH_00636 2.2e-96 ywrO S Flavodoxin-like fold
HEOGLLMH_00637 1.4e-43 ywrO S Flavodoxin-like fold
HEOGLLMH_00638 4.3e-45 K Acetyltransferase (GNAT) domain
HEOGLLMH_00639 2.6e-56 azoR I NADPH-dependent FMN reductase
HEOGLLMH_00640 3.9e-85 GM NAD(P)H-binding
HEOGLLMH_00641 7.4e-99 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HEOGLLMH_00642 3.3e-78 K Transcriptional regulator
HEOGLLMH_00643 7.7e-29 S Doxx family
HEOGLLMH_00644 1.2e-63 K BetI-type transcriptional repressor, C-terminal
HEOGLLMH_00645 1.4e-141 yhfP 1.1.1.1 C Alcohol dehydrogenase GroES-like domain
HEOGLLMH_00646 5.3e-71 M nucleic acid phosphodiester bond hydrolysis
HEOGLLMH_00647 5.9e-109 yobL L nucleic acid phosphodiester bond hydrolysis
HEOGLLMH_00648 8.3e-46 S SMI1-KNR4 cell-wall
HEOGLLMH_00649 1.3e-34 yddB S Conjugative transposon protein TcpC
HEOGLLMH_00651 2.2e-35
HEOGLLMH_00652 1.1e-35 yddA
HEOGLLMH_00658 9.1e-31
HEOGLLMH_00659 2.5e-14 nicK L Replication initiation factor
HEOGLLMH_00660 7.1e-191 L Belongs to the 'phage' integrase family
HEOGLLMH_00668 3e-59 ydcK S Belongs to the SprT family
HEOGLLMH_00669 1.7e-14
HEOGLLMH_00670 0.0 yhgF K COG2183 Transcriptional accessory protein
HEOGLLMH_00671 9.7e-109 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
HEOGLLMH_00672 1.4e-139 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEOGLLMH_00673 2.1e-85 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HEOGLLMH_00674 1.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
HEOGLLMH_00675 6.2e-31 rsbU 3.1.3.3 KT phosphatase
HEOGLLMH_00676 3.9e-129 rsbU 3.1.3.3 KT phosphatase
HEOGLLMH_00677 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HEOGLLMH_00678 6.8e-57 rsbS T antagonist
HEOGLLMH_00679 6.1e-146 rsbR T Positive regulator of sigma-B
HEOGLLMH_00680 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
HEOGLLMH_00681 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HEOGLLMH_00682 1.7e-218 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HEOGLLMH_00683 7.6e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
HEOGLLMH_00684 4.7e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HEOGLLMH_00685 3.1e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
HEOGLLMH_00686 1.1e-262 ydbT S Membrane
HEOGLLMH_00687 2.1e-82 ydbS S Bacterial PH domain
HEOGLLMH_00688 2.9e-247 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HEOGLLMH_00689 8e-260 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HEOGLLMH_00690 9.3e-203 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HEOGLLMH_00691 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HEOGLLMH_00692 2.4e-119 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEOGLLMH_00693 5.8e-09 S Fur-regulated basic protein A
HEOGLLMH_00694 1.5e-10 S Fur-regulated basic protein B
HEOGLLMH_00695 1.4e-206 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
HEOGLLMH_00696 2.1e-52 ydbL
HEOGLLMH_00697 7.4e-130 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HEOGLLMH_00698 5e-173 ydbJ V ABC transporter, ATP-binding protein
HEOGLLMH_00699 3.2e-160 ydbI S AI-2E family transporter
HEOGLLMH_00700 1.7e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEOGLLMH_00701 6.7e-119 dctR T COG4565 Response regulator of citrate malate metabolism
HEOGLLMH_00702 2.7e-299 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HEOGLLMH_00703 3.2e-200 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HEOGLLMH_00704 6.5e-156 ydbD P Catalase
HEOGLLMH_00705 1.4e-62 ydbC S Domain of unknown function (DUF4937
HEOGLLMH_00706 1.7e-57 ydbB G Cupin domain
HEOGLLMH_00708 6.8e-142 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
HEOGLLMH_00709 4.1e-54 yvaE P Small Multidrug Resistance protein
HEOGLLMH_00710 2.2e-72 yvaD S Family of unknown function (DUF5360)
HEOGLLMH_00711 6.5e-34 ydaT
HEOGLLMH_00713 7e-226 mntH P H( )-stimulated, divalent metal cation uptake system
HEOGLLMH_00714 2.1e-39
HEOGLLMH_00716 7.9e-75
HEOGLLMH_00719 4.6e-44 K acetyltransferase
HEOGLLMH_00720 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HEOGLLMH_00721 4.7e-76 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HEOGLLMH_00722 0.0 ydaO E amino acid
HEOGLLMH_00723 0.0 ydaN S Bacterial cellulose synthase subunit
HEOGLLMH_00724 8.5e-266 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
HEOGLLMH_00725 6.1e-40 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
HEOGLLMH_00726 1.9e-136 ydaK T Diguanylate cyclase, GGDEF domain
HEOGLLMH_00727 3.9e-201 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
HEOGLLMH_00728 1.4e-256 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HEOGLLMH_00729 9.9e-62 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HEOGLLMH_00730 7.5e-35 lrpC K Transcriptional regulator
HEOGLLMH_00731 6.6e-23 lrpC K Transcriptional regulator
HEOGLLMH_00732 1.3e-47 ydzA EGP Major facilitator Superfamily
HEOGLLMH_00733 4.6e-138 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HEOGLLMH_00734 4e-77 ydaG 1.4.3.5 S general stress protein
HEOGLLMH_00735 5.7e-32 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HEOGLLMH_00736 1.6e-73 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HEOGLLMH_00737 3e-95 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
HEOGLLMH_00738 3.7e-162 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEOGLLMH_00739 2.6e-288 ydaB IQ acyl-CoA ligase
HEOGLLMH_00740 0.0 mtlR K transcriptional regulator, MtlR
HEOGLLMH_00741 7.5e-174 ydhF S Oxidoreductase
HEOGLLMH_00742 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
HEOGLLMH_00743 5.1e-56 yczJ S biosynthesis
HEOGLLMH_00745 2.4e-118 ycsK E anatomical structure formation involved in morphogenesis
HEOGLLMH_00746 8.9e-131 kipR K Transcriptional regulator
HEOGLLMH_00747 3.1e-20 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HEOGLLMH_00748 1.1e-50 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HEOGLLMH_00749 8.3e-42 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HEOGLLMH_00750 5.9e-85 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
HEOGLLMH_00751 2.3e-35 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
HEOGLLMH_00752 6e-151 ycsI S Belongs to the D-glutamate cyclase family
HEOGLLMH_00753 4.7e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
HEOGLLMH_00754 8.8e-133 ycsF S Belongs to the UPF0271 (lamB) family
HEOGLLMH_00755 2.1e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HEOGLLMH_00757 5.1e-66 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HEOGLLMH_00758 6.9e-130 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
HEOGLLMH_00759 3.8e-64 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
HEOGLLMH_00760 4e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HEOGLLMH_00761 2.2e-71 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
HEOGLLMH_00762 7.7e-138 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
HEOGLLMH_00763 1.6e-55
HEOGLLMH_00764 5.6e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
HEOGLLMH_00765 2.3e-298 ycnJ P protein, homolog of Cu resistance protein CopC
HEOGLLMH_00766 3.5e-98 ycnI S protein conserved in bacteria
HEOGLLMH_00767 1.1e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEOGLLMH_00768 3.6e-149 glcU U Glucose uptake
HEOGLLMH_00769 1.4e-234 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HEOGLLMH_00770 2.7e-220 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEOGLLMH_00771 1.5e-256 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEOGLLMH_00772 8.8e-53 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
HEOGLLMH_00773 1e-44 ycnE S Monooxygenase
HEOGLLMH_00774 5.2e-136 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
HEOGLLMH_00775 5.4e-153 ycnC K Transcriptional regulator
HEOGLLMH_00776 1e-249 ycnB EGP Major facilitator Superfamily
HEOGLLMH_00777 3.8e-63 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
HEOGLLMH_00778 5.6e-98 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
HEOGLLMH_00779 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
HEOGLLMH_00780 1.3e-143 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEOGLLMH_00781 3e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEOGLLMH_00782 1.9e-253 lysC 2.7.2.4 E Belongs to the aspartokinase family
HEOGLLMH_00784 1.9e-81 S aspartate phosphatase
HEOGLLMH_00785 5.3e-113 T PhoQ Sensor
HEOGLLMH_00786 3.1e-67 T PhoQ Sensor
HEOGLLMH_00787 1.1e-41 T PhoQ Sensor
HEOGLLMH_00788 2.2e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEOGLLMH_00789 3.6e-223 yclI V ABC transporter (permease) YclI
HEOGLLMH_00790 2.7e-123 yclH P ABC transporter
HEOGLLMH_00791 8.4e-254 yxeQ S MmgE/PrpD family
HEOGLLMH_00792 1.1e-217 yxeP 3.5.1.47 E hydrolase activity
HEOGLLMH_00793 4.1e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
HEOGLLMH_00794 4.5e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
HEOGLLMH_00795 7.9e-143 yxeM M Belongs to the bacterial solute-binding protein 3 family
HEOGLLMH_00796 6.9e-61 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEOGLLMH_00797 7.5e-255 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEOGLLMH_00798 6.6e-196 gerKB F Spore germination protein
HEOGLLMH_00799 1.1e-236 gerKC S spore germination
HEOGLLMH_00800 1.2e-294 gerKA EG Spore germination protein
HEOGLLMH_00802 1.9e-282 yclG M Pectate lyase superfamily protein
HEOGLLMH_00803 4.1e-270 dtpT E amino acid peptide transporter
HEOGLLMH_00804 3.4e-77 yclD
HEOGLLMH_00805 2e-38 bsdD 4.1.1.61 S response to toxic substance
HEOGLLMH_00806 2.2e-281 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HEOGLLMH_00807 9.3e-101 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HEOGLLMH_00808 3.6e-157 bsdA K LysR substrate binding domain
HEOGLLMH_00809 6.1e-143 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HEOGLLMH_00810 6.3e-120 tcyB P COG0765 ABC-type amino acid transport system, permease component
HEOGLLMH_00811 2.4e-133 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HEOGLLMH_00812 2.1e-118 S Histidine kinase
HEOGLLMH_00814 6.5e-111 yczE S membrane
HEOGLLMH_00815 6.1e-112 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HEOGLLMH_00816 2.9e-213 ycxD K GntR family transcriptional regulator
HEOGLLMH_00817 7.5e-148 ycxC EG EamA-like transporter family
HEOGLLMH_00818 2.9e-208 EGP Major Facilitator Superfamily
HEOGLLMH_00819 2.2e-131 srfAD Q thioesterase
HEOGLLMH_00820 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
HEOGLLMH_00821 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEOGLLMH_00822 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEOGLLMH_00823 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEOGLLMH_00824 1.1e-234 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEOGLLMH_00825 6.3e-63 hxlR K transcriptional
HEOGLLMH_00826 8.3e-46 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
HEOGLLMH_00827 6.9e-48 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
HEOGLLMH_00828 2.4e-77 nucA M Deoxyribonuclease NucA/NucB
HEOGLLMH_00829 2.9e-69 nin S Competence protein J (ComJ)
HEOGLLMH_00830 1.6e-295 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HEOGLLMH_00831 3.2e-50 S Protein of unknown function (DUF2680)
HEOGLLMH_00832 6.9e-23 yckC S membrane
HEOGLLMH_00833 2.2e-35 yckC S membrane
HEOGLLMH_00834 7.1e-214 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HEOGLLMH_00835 7.8e-227 yciC S GTPases (G3E family)
HEOGLLMH_00836 5.3e-223 nasA P COG2223 Nitrate nitrite transporter
HEOGLLMH_00837 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
HEOGLLMH_00838 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEOGLLMH_00839 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HEOGLLMH_00840 3.5e-57 nirD 1.7.1.15 P Nitrite reductase
HEOGLLMH_00841 2.1e-114 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HEOGLLMH_00842 3.5e-123 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HEOGLLMH_00843 1.7e-190 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HEOGLLMH_00844 6.2e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
HEOGLLMH_00845 2.7e-242 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEOGLLMH_00846 1.1e-292 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HEOGLLMH_00847 1.8e-184 ycgM E Proline dehydrogenase
HEOGLLMH_00848 3.1e-147 ycgL S Predicted nucleotidyltransferase
HEOGLLMH_00849 4.5e-185 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HEOGLLMH_00850 1.6e-38 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HEOGLLMH_00851 3.7e-42 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HEOGLLMH_00852 1.3e-230 G COG0477 Permeases of the major facilitator superfamily
HEOGLLMH_00853 1.9e-147 4.2.1.118 G Xylose isomerase-like TIM barrel
HEOGLLMH_00854 4.3e-109 tmrB S AAA domain
HEOGLLMH_00856 3.1e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HEOGLLMH_00857 7.6e-114 ycgI S Domain of unknown function (DUF1989)
HEOGLLMH_00858 9.8e-247 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
HEOGLLMH_00859 3.8e-150 yqcI S YqcI/YcgG family
HEOGLLMH_00860 1e-113 ycgF E Lysine exporter protein LysE YggA
HEOGLLMH_00861 3.7e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
HEOGLLMH_00862 2.8e-261 mdr EGP Major facilitator Superfamily
HEOGLLMH_00863 3.7e-179 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HEOGLLMH_00864 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
HEOGLLMH_00865 8.2e-58 ycgB
HEOGLLMH_00866 2.4e-230 ycgA S Membrane
HEOGLLMH_00867 1.1e-211 amhX S amidohydrolase
HEOGLLMH_00868 3.1e-164 opuAC E glycine betaine
HEOGLLMH_00869 1.6e-138 opuAB P glycine betaine
HEOGLLMH_00870 2.5e-228 proV 3.6.3.32 E glycine betaine
HEOGLLMH_00872 4.8e-216 naiP P Uncharacterised MFS-type transporter YbfB
HEOGLLMH_00873 2.3e-193 yceH P Belongs to the TelA family
HEOGLLMH_00874 0.0 yceG S Putative component of 'biosynthetic module'
HEOGLLMH_00875 9.7e-138 terC P Protein of unknown function (DUF475)
HEOGLLMH_00876 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
HEOGLLMH_00877 4.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
HEOGLLMH_00878 1.3e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
HEOGLLMH_00879 4.7e-185 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEOGLLMH_00880 2e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HEOGLLMH_00881 7.9e-120 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HEOGLLMH_00882 6e-164 adcA P Belongs to the bacterial solute-binding protein 9 family
HEOGLLMH_00883 1.2e-182 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
HEOGLLMH_00884 1.2e-121 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
HEOGLLMH_00885 7.3e-141 IQ Enoyl-(Acyl carrier protein) reductase
HEOGLLMH_00886 5.1e-188 S response regulator aspartate phosphatase
HEOGLLMH_00887 4.9e-90 cwlK M D-alanyl-D-alanine carboxypeptidase
HEOGLLMH_00888 7.2e-222 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
HEOGLLMH_00889 3.1e-95 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
HEOGLLMH_00890 9.1e-148 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
HEOGLLMH_00891 1.1e-122 ycdA S Domain of unknown function (DUF5105)
HEOGLLMH_00892 9e-43 ycdA S Domain of unknown function (DUF5105)
HEOGLLMH_00893 2.5e-172 yccK C Aldo keto reductase
HEOGLLMH_00894 3.7e-196 yccF K DNA-templated transcriptional preinitiation complex assembly
HEOGLLMH_00895 2.8e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HEOGLLMH_00896 2.5e-184 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HEOGLLMH_00897 5.5e-90 yxaF K Transcriptional regulator
HEOGLLMH_00898 1.1e-238 lmrB EGP the major facilitator superfamily
HEOGLLMH_00899 6.9e-209 ycbU E Selenocysteine lyase
HEOGLLMH_00900 9.1e-121 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HEOGLLMH_00901 4.7e-126 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HEOGLLMH_00902 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HEOGLLMH_00903 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
HEOGLLMH_00904 5.1e-80 sleB 3.5.1.28 M Cell wall
HEOGLLMH_00905 5.6e-62 ycbP S Protein of unknown function (DUF2512)
HEOGLLMH_00906 1.3e-55 traF CO Thioredoxin
HEOGLLMH_00907 2e-62 mhqP S DoxX
HEOGLLMH_00908 4.1e-183 ydfO E COG0346 Lactoylglutathione lyase and related lyases
HEOGLLMH_00909 7.8e-48 ydfN C nitroreductase
HEOGLLMH_00910 4.4e-49 ydfN C nitroreductase
HEOGLLMH_00911 2e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEOGLLMH_00912 8.7e-34 L Transposase
HEOGLLMH_00913 8.2e-26 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
HEOGLLMH_00914 1.4e-37 ycbJ S Macrolide 2'-phosphotransferase
HEOGLLMH_00915 2.3e-75 glnL T Regulator
HEOGLLMH_00916 5.5e-76 glnL T Regulator
HEOGLLMH_00917 2.8e-211 phoQ 2.7.13.3 T Histidine kinase
HEOGLLMH_00918 1.4e-189 glsA 3.5.1.2 E Belongs to the glutaminase family
HEOGLLMH_00919 1.6e-258 agcS E Sodium alanine symporter
HEOGLLMH_00920 5.1e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
HEOGLLMH_00921 2.7e-78 mmuP E amino acid
HEOGLLMH_00922 3.7e-120 mmuP E amino acid
HEOGLLMH_00923 1.1e-43 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HEOGLLMH_00924 1.2e-143 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HEOGLLMH_00925 1.9e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEOGLLMH_00926 4.3e-191 yceA S Belongs to the UPF0176 family
HEOGLLMH_00927 1.2e-42 ybfN
HEOGLLMH_00928 7.3e-152 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HEOGLLMH_00929 1.9e-86 ybfM S SNARE associated Golgi protein
HEOGLLMH_00930 5e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HEOGLLMH_00931 1.1e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HEOGLLMH_00932 1.7e-201 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
HEOGLLMH_00933 1.2e-82 K Helix-turn-helix XRE-family like proteins
HEOGLLMH_00934 1.9e-19
HEOGLLMH_00935 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
HEOGLLMH_00938 6.6e-119 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
HEOGLLMH_00939 1.2e-106 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
HEOGLLMH_00940 1.3e-16 S Protein of unknown function (DUF2651)
HEOGLLMH_00941 9.7e-219 glpT G -transporter
HEOGLLMH_00942 1.8e-164 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HEOGLLMH_00943 2.6e-15 S Protein of unknown function (DUF2651)
HEOGLLMH_00945 3.9e-43
HEOGLLMH_00946 1.5e-45 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HEOGLLMH_00947 5.6e-115 ybeC E amino acid
HEOGLLMH_00948 3.4e-165 ybeC E amino acid
HEOGLLMH_00949 9.2e-40 ybyB
HEOGLLMH_00950 3.5e-110 yqeB
HEOGLLMH_00951 5.8e-39 csgA S Sigma-G-dependent sporulation-specific SASP protein
HEOGLLMH_00952 4.5e-77 S Domain of unknown function (DUF4879)
HEOGLLMH_00953 4.7e-24
HEOGLLMH_00954 5e-199 V ABC-2 family transporter protein
HEOGLLMH_00955 8.9e-207 V COG0842 ABC-type multidrug transport system, permease component
HEOGLLMH_00956 1.4e-167 V COG1131 ABC-type multidrug transport system, ATPase component
HEOGLLMH_00957 3.8e-111 KT LuxR family transcriptional regulator
HEOGLLMH_00958 1.6e-24 T COG4585 Signal transduction histidine kinase
HEOGLLMH_00959 7.1e-126 T COG4585 Signal transduction histidine kinase
HEOGLLMH_00960 2.3e-93 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HEOGLLMH_00961 8.9e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
HEOGLLMH_00962 8e-73 yxaD K helix_turn_helix multiple antibiotic resistance protein
HEOGLLMH_00963 1.7e-93 yxaC M effector of murein hydrolase
HEOGLLMH_00964 1.3e-153 dkgB S Aldo/keto reductase family
HEOGLLMH_00965 3.2e-132 ybdO S Domain of unknown function (DUF4885)
HEOGLLMH_00966 2.4e-100 ybdN
HEOGLLMH_00967 1.5e-73 S ABC-2 family transporter protein
HEOGLLMH_00968 1.4e-156 V ATPases associated with a variety of cellular activities
HEOGLLMH_00969 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HEOGLLMH_00970 2.6e-46 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HEOGLLMH_00971 8.4e-177 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HEOGLLMH_00972 9.3e-183 ybbR S protein conserved in bacteria
HEOGLLMH_00973 2.8e-13 ybbR S protein conserved in bacteria
HEOGLLMH_00974 1e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HEOGLLMH_00975 1.2e-21 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HEOGLLMH_00976 4.1e-78 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HEOGLLMH_00977 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
HEOGLLMH_00983 2.3e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
HEOGLLMH_00984 4.1e-86 ybbJ J acetyltransferase
HEOGLLMH_00985 1.5e-98 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HEOGLLMH_00986 2.5e-50 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HEOGLLMH_00987 5.6e-237 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HEOGLLMH_00988 6.6e-38 yfeW 3.4.16.4 V Belongs to the UPF0214 family
HEOGLLMH_00989 1.7e-198 yfeW 3.4.16.4 V Belongs to the UPF0214 family
HEOGLLMH_00990 8.4e-260 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
HEOGLLMH_00991 9.8e-77 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
HEOGLLMH_00992 2.3e-237 ybbC 3.2.1.52 S protein conserved in bacteria
HEOGLLMH_00993 1.5e-310 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
HEOGLLMH_00994 8.6e-85 feuA P Iron-uptake system-binding protein
HEOGLLMH_00995 1.7e-97 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEOGLLMH_00996 8.2e-70 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEOGLLMH_00997 4.7e-180 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEOGLLMH_00998 2.3e-115 ybbA S Putative esterase
HEOGLLMH_00999 3.7e-174 ybaS 1.1.1.58 S Na -dependent transporter
HEOGLLMH_01000 2.7e-226 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
HEOGLLMH_01001 5.3e-110 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
HEOGLLMH_01002 6.1e-71 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
HEOGLLMH_01003 5.7e-180 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
HEOGLLMH_01004 1.9e-247 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEOGLLMH_01005 2.1e-219 glcP G Major Facilitator Superfamily
HEOGLLMH_01006 3.4e-39 S COG NOG14552 non supervised orthologous group
HEOGLLMH_01009 1.6e-08
HEOGLLMH_01012 3.4e-39 S COG NOG14552 non supervised orthologous group
HEOGLLMH_01013 4.2e-133 pdaB 3.5.1.104 G Polysaccharide deacetylase
HEOGLLMH_01014 6e-103 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
HEOGLLMH_01015 7.1e-75 gerD
HEOGLLMH_01016 6.7e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HEOGLLMH_01017 2.1e-134 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HEOGLLMH_01018 4.5e-79 ybaK S Protein of unknown function (DUF2521)
HEOGLLMH_01019 1.1e-36 yizA S Damage-inducible protein DinB
HEOGLLMH_01020 1.8e-36 yizA S Damage-inducible protein DinB
HEOGLLMH_01021 8.2e-145 ybaJ Q Methyltransferase domain
HEOGLLMH_01022 3.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HEOGLLMH_01023 1.3e-27 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HEOGLLMH_01024 2.4e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HEOGLLMH_01025 1.4e-118 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEOGLLMH_01026 2.5e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEOGLLMH_01027 3.9e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEOGLLMH_01028 4.7e-58 rplQ J Ribosomal protein L17
HEOGLLMH_01029 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEOGLLMH_01030 2.8e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HEOGLLMH_01031 1.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HEOGLLMH_01032 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HEOGLLMH_01033 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HEOGLLMH_01034 1.8e-141 map 3.4.11.18 E Methionine aminopeptidase
HEOGLLMH_01035 1.7e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HEOGLLMH_01036 1.6e-109 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HEOGLLMH_01037 5.9e-96 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HEOGLLMH_01038 1.3e-28 rplO J binds to the 23S rRNA
HEOGLLMH_01039 9.4e-20 rplO J binds to the 23S rRNA
HEOGLLMH_01040 1.9e-23 rpmD J Ribosomal protein L30
HEOGLLMH_01041 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HEOGLLMH_01042 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HEOGLLMH_01043 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HEOGLLMH_01044 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HEOGLLMH_01045 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HEOGLLMH_01046 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HEOGLLMH_01047 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HEOGLLMH_01048 2.3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HEOGLLMH_01049 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HEOGLLMH_01050 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HEOGLLMH_01051 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HEOGLLMH_01052 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HEOGLLMH_01053 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HEOGLLMH_01054 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HEOGLLMH_01055 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HEOGLLMH_01056 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HEOGLLMH_01057 1.7e-76 rplD J Forms part of the polypeptide exit tunnel
HEOGLLMH_01058 9.8e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HEOGLLMH_01059 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HEOGLLMH_01060 9.8e-188 ybaC 3.4.11.5 S Alpha/beta hydrolase family
HEOGLLMH_01061 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HEOGLLMH_01062 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HEOGLLMH_01063 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HEOGLLMH_01064 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HEOGLLMH_01065 5.5e-34 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
HEOGLLMH_01066 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEOGLLMH_01067 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEOGLLMH_01068 1.3e-102 rsmC 2.1.1.172 J Methyltransferase
HEOGLLMH_01069 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HEOGLLMH_01070 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HEOGLLMH_01071 8.1e-111 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HEOGLLMH_01072 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HEOGLLMH_01073 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
HEOGLLMH_01074 2.6e-13 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HEOGLLMH_01075 2.1e-76 sigH K Belongs to the sigma-70 factor family
HEOGLLMH_01076 1.5e-22 sigH K Belongs to the sigma-70 factor family
HEOGLLMH_01077 3.7e-58 yacP S RNA-binding protein containing a PIN domain
HEOGLLMH_01078 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEOGLLMH_01079 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HEOGLLMH_01080 1.7e-196 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HEOGLLMH_01081 3.1e-59 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HEOGLLMH_01082 4.4e-56 cysE 2.3.1.30 E Serine acetyltransferase
HEOGLLMH_01083 3.1e-278 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HEOGLLMH_01084 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HEOGLLMH_01085 1e-122 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HEOGLLMH_01086 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
HEOGLLMH_01087 7.8e-186 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HEOGLLMH_01088 1.2e-228 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HEOGLLMH_01089 1.2e-258 clpC O Belongs to the ClpA ClpB family
HEOGLLMH_01090 1.9e-153 clpC O Belongs to the ClpA ClpB family
HEOGLLMH_01091 1.9e-203 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HEOGLLMH_01092 5.9e-82 mcsA 2.7.14.1 S protein with conserved CXXC pairs
HEOGLLMH_01093 7.5e-77 ctsR K Belongs to the CtsR family
HEOGLLMH_01094 3.4e-39 S COG NOG14552 non supervised orthologous group
HEOGLLMH_01099 2e-08
HEOGLLMH_01104 3.4e-39 S COG NOG14552 non supervised orthologous group
HEOGLLMH_01105 5.4e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HEOGLLMH_01106 2.9e-142 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEOGLLMH_01107 3.6e-36 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEOGLLMH_01108 4.5e-29 yazB K transcriptional
HEOGLLMH_01109 3.2e-62 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HEOGLLMH_01110 1.9e-18 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HEOGLLMH_01111 2.4e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HEOGLLMH_01112 7.7e-127 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HEOGLLMH_01113 3.8e-162 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
HEOGLLMH_01114 1.8e-107 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
HEOGLLMH_01115 1.3e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HEOGLLMH_01116 5.7e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HEOGLLMH_01117 8.3e-157 yacD 5.2.1.8 O peptidyl-prolyl isomerase
HEOGLLMH_01118 1.1e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HEOGLLMH_01119 3.1e-144 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HEOGLLMH_01120 1.8e-107 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HEOGLLMH_01121 3.4e-223 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HEOGLLMH_01122 5.1e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HEOGLLMH_01123 1.3e-273 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HEOGLLMH_01124 3.6e-185 KLT serine threonine protein kinase
HEOGLLMH_01125 1.1e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
HEOGLLMH_01126 1.3e-28 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
HEOGLLMH_01127 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
HEOGLLMH_01130 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
HEOGLLMH_01131 4.1e-57 divIC D Septum formation initiator
HEOGLLMH_01132 5.8e-104 yabQ S spore cortex biosynthesis protein
HEOGLLMH_01133 1.9e-49 yabP S Sporulation protein YabP
HEOGLLMH_01134 5.6e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HEOGLLMH_01135 7e-54 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HEOGLLMH_01136 1.3e-55 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HEOGLLMH_01137 6.9e-123 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HEOGLLMH_01138 1.5e-36 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEOGLLMH_01139 3.2e-173 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEOGLLMH_01140 1.4e-90 spoVT K stage V sporulation protein
HEOGLLMH_01141 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HEOGLLMH_01142 3.7e-40 yabK S Peptide ABC transporter permease
HEOGLLMH_01143 9.4e-106 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HEOGLLMH_01144 2e-106 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HEOGLLMH_01145 7.2e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HEOGLLMH_01146 6.1e-244 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HEOGLLMH_01147 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HEOGLLMH_01148 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
HEOGLLMH_01149 1.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HEOGLLMH_01150 2.1e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HEOGLLMH_01151 2.9e-27 sspF S DNA topological change
HEOGLLMH_01152 7.8e-39 veg S protein conserved in bacteria
HEOGLLMH_01153 5.4e-97 yabG S peptidase
HEOGLLMH_01154 2.9e-134 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HEOGLLMH_01156 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HEOGLLMH_01157 2.4e-37 rpfB GH23 T protein conserved in bacteria
HEOGLLMH_01158 3.7e-74 rpfB GH23 T protein conserved in bacteria
HEOGLLMH_01159 6.3e-44 rpfB GH23 T protein conserved in bacteria
HEOGLLMH_01160 1.5e-143 tatD L hydrolase, TatD
HEOGLLMH_01161 7.3e-144 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HEOGLLMH_01162 1.4e-225 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HEOGLLMH_01163 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
HEOGLLMH_01164 9e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HEOGLLMH_01165 4.7e-48 yazA L endonuclease containing a URI domain
HEOGLLMH_01166 1.9e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
HEOGLLMH_01167 8.3e-31 yabA L Involved in initiation control of chromosome replication
HEOGLLMH_01168 8.8e-145 yaaT S stage 0 sporulation protein
HEOGLLMH_01169 1.4e-156 holB 2.7.7.7 L DNA polymerase III
HEOGLLMH_01170 9.4e-33 yaaR S protein conserved in bacteria
HEOGLLMH_01171 7.5e-55 yaaQ S protein conserved in bacteria
HEOGLLMH_01172 2.2e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HEOGLLMH_01173 6.4e-268 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
HEOGLLMH_01174 1.9e-190 yaaN P Belongs to the TelA family
HEOGLLMH_01175 5.1e-105 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HEOGLLMH_01176 2.2e-30 csfB S Inhibitor of sigma-G Gin
HEOGLLMH_01179 3.4e-39 S COG NOG14552 non supervised orthologous group
HEOGLLMH_01180 2e-19 bofA S Sigma-K factor-processing regulatory protein BofA
HEOGLLMH_01181 3.6e-32 yaaL S Protein of unknown function (DUF2508)
HEOGLLMH_01182 1.6e-93 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HEOGLLMH_01183 2.8e-33 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HEOGLLMH_01184 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEOGLLMH_01185 3.5e-85 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HEOGLLMH_01186 2.2e-99 yaaI Q COG1335 Amidases related to nicotinamidase
HEOGLLMH_01187 1.3e-211 yaaH M Glycoside Hydrolase Family
HEOGLLMH_01188 4.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
HEOGLLMH_01189 3.1e-121 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
HEOGLLMH_01190 1.3e-09
HEOGLLMH_01191 2.4e-201 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HEOGLLMH_01192 2.4e-205 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HEOGLLMH_01193 9.5e-109 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HEOGLLMH_01194 5.7e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HEOGLLMH_01195 3.6e-249 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HEOGLLMH_01196 1.7e-165 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HEOGLLMH_01197 4.5e-92 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HEOGLLMH_01198 8.8e-184 yaaC S YaaC-like Protein
HEOGLLMH_01201 3.4e-39 S COG NOG14552 non supervised orthologous group
HEOGLLMH_01202 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEOGLLMH_01203 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEOGLLMH_01204 8.1e-38 yaaB S Domain of unknown function (DUF370)
HEOGLLMH_01205 7e-127 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HEOGLLMH_01206 3.5e-43 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HEOGLLMH_01207 2.4e-33 yaaA S S4 domain
HEOGLLMH_01208 3.6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HEOGLLMH_01209 4.7e-249 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HEOGLLMH_01210 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HEOGLLMH_01211 1.9e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HEOGLLMH_01212 4.5e-112 jag S single-stranded nucleic acid binding R3H
HEOGLLMH_01213 8.9e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HEOGLLMH_01214 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HEOGLLMH_01215 4.2e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HEOGLLMH_01216 1.3e-151 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HEOGLLMH_01217 9.2e-136 soj D COG1192 ATPases involved in chromosome partitioning
HEOGLLMH_01218 7.8e-118 spo0J K Belongs to the ParB family
HEOGLLMH_01219 6.2e-111 yyaC S Sporulation protein YyaC
HEOGLLMH_01220 8.8e-27 4.2.1.103 K FR47-like protein
HEOGLLMH_01221 9.4e-44 4.2.1.103 K FR47-like protein
HEOGLLMH_01222 2.4e-176 yyaD S Membrane
HEOGLLMH_01223 2.3e-33 yyzM S protein conserved in bacteria
HEOGLLMH_01224 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEOGLLMH_01225 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HEOGLLMH_01226 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
HEOGLLMH_01227 3.8e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HEOGLLMH_01228 1.1e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HEOGLLMH_01229 7.7e-95 adaA 3.2.2.21 K Transcriptional regulator
HEOGLLMH_01230 3.6e-102 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HEOGLLMH_01231 8.6e-147 xth 3.1.11.2 L exodeoxyribonuclease III
HEOGLLMH_01232 4.8e-179 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
HEOGLLMH_01233 8.9e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEOGLLMH_01234 9.5e-121 ydjK G Sugar (and other) transporter
HEOGLLMH_01235 2.7e-83 ydjK G Sugar (and other) transporter
HEOGLLMH_01236 6.6e-162 yyaK S CAAX protease self-immunity
HEOGLLMH_01237 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HEOGLLMH_01238 4.7e-131 ydfC EG EamA-like transporter family
HEOGLLMH_01239 5.6e-120 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEOGLLMH_01240 6.2e-106 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEOGLLMH_01241 8e-143 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HEOGLLMH_01242 1.6e-147 K Transcriptional regulator
HEOGLLMH_01243 2.1e-67 4.1.1.44 S Carboxymuconolactone decarboxylase family
HEOGLLMH_01244 2.3e-164 eaeH M Domain of Unknown Function (DUF1259)
HEOGLLMH_01245 1e-75 yjcF S Acetyltransferase (GNAT) domain
HEOGLLMH_01246 1.3e-28 yybA 2.3.1.57 K transcriptional
HEOGLLMH_01247 3.8e-154 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HEOGLLMH_01248 3.2e-69 ydgJ K Winged helix DNA-binding domain
HEOGLLMH_01249 5.6e-115 drgA C nitroreductase
HEOGLLMH_01250 2.2e-55 ypaA S Protein of unknown function (DUF1304)
HEOGLLMH_01251 2.8e-165 gltC K Transcriptional regulator
HEOGLLMH_01252 5.3e-215 ynfM EGP Major facilitator Superfamily
HEOGLLMH_01253 3.3e-100 E LysE type translocator
HEOGLLMH_01254 9.9e-163 yfiE K LysR substrate binding domain
HEOGLLMH_01255 3.1e-162 G Major Facilitator Superfamily
HEOGLLMH_01256 1.4e-58 dinB S PFAM DinB family protein
HEOGLLMH_01257 1.8e-116 K FCD domain
HEOGLLMH_01258 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
HEOGLLMH_01259 2.2e-78 sacB 2.4.1.10 GH68 M levansucrase activity
HEOGLLMH_01260 2e-117 sacB 2.4.1.10 GH68 M levansucrase activity
HEOGLLMH_01261 1.6e-149 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HEOGLLMH_01262 3.9e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
HEOGLLMH_01263 1e-65 ydeP3 K Transcriptional regulator
HEOGLLMH_01264 6.5e-85 cotF M Spore coat protein
HEOGLLMH_01266 1.4e-86 yybS S membrane
HEOGLLMH_01267 2.1e-14 yybS S membrane
HEOGLLMH_01268 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HEOGLLMH_01269 3.1e-63 rplI J binds to the 23S rRNA
HEOGLLMH_01270 1.4e-121 KLT COG0515 Serine threonine protein kinase
HEOGLLMH_01271 9.8e-123 S GlcNAc-PI de-N-acetylase
HEOGLLMH_01272 4.3e-250 M Glycosyltransferase Family 4
HEOGLLMH_01273 5e-211 S Carbamoyl-phosphate synthase L chain, ATP binding domain
HEOGLLMH_01274 1.6e-241 M Glycosyltransferase Family 4
HEOGLLMH_01275 5.7e-37 M 4-amino-4-deoxy-L-arabinose transferase activity
HEOGLLMH_01276 3.5e-17 yycC K YycC-like protein
HEOGLLMH_01278 6.1e-28 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
HEOGLLMH_01279 2.8e-252 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HEOGLLMH_01280 3.4e-73 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEOGLLMH_01281 2.3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HEOGLLMH_01286 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEOGLLMH_01287 0.0 vicK 2.7.13.3 T Histidine kinase
HEOGLLMH_01288 2.5e-261 yycH S protein conserved in bacteria
HEOGLLMH_01289 1.2e-152 yycI S protein conserved in bacteria
HEOGLLMH_01290 1.8e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HEOGLLMH_01291 9.8e-186 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEOGLLMH_01292 3.2e-22 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEOGLLMH_01293 8e-10 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEOGLLMH_01294 1.4e-251 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
HEOGLLMH_01295 6.9e-192 2.7.7.73, 2.7.7.80 H ThiF family
HEOGLLMH_01296 1.6e-149
HEOGLLMH_01297 5e-65
HEOGLLMH_01298 4.5e-195 S Major Facilitator Superfamily
HEOGLLMH_01299 3e-306 S ABC transporter
HEOGLLMH_01300 4.5e-145 1.14.11.27 P peptidyl-arginine hydroxylation
HEOGLLMH_01301 6.3e-260 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HEOGLLMH_01302 2.2e-42 sdpR K transcriptional
HEOGLLMH_01303 7.2e-62 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HEOGLLMH_01304 4.6e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
HEOGLLMH_01305 1.2e-258 rocE E amino acid
HEOGLLMH_01306 1.8e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
HEOGLLMH_01307 4.7e-202 S Histidine kinase
HEOGLLMH_01309 2e-85 yycN 2.3.1.128 K Acetyltransferase
HEOGLLMH_01310 3.5e-185 C oxidoreductases (related to aryl-alcohol dehydrogenases)
HEOGLLMH_01311 8.3e-134 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HEOGLLMH_01312 6.8e-157 yycP
HEOGLLMH_01313 8.1e-31 yycP
HEOGLLMH_01315 7.9e-08 S YyzF-like protein
HEOGLLMH_01316 3.4e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HEOGLLMH_01317 2.4e-108 mjecl24 D Involved in chromosome partitioning
HEOGLLMH_01318 3.7e-106
HEOGLLMH_01319 3.2e-45
HEOGLLMH_01320 1.8e-52
HEOGLLMH_01322 5.1e-10
HEOGLLMH_01323 8.5e-19
HEOGLLMH_01324 2.3e-41 S Fusaric acid resistance protein-like
HEOGLLMH_01325 1.2e-71 S Fusaric acid resistance protein-like
HEOGLLMH_01326 1.1e-144 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HEOGLLMH_01327 3.3e-10 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
HEOGLLMH_01328 1.7e-73 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
HEOGLLMH_01329 2.8e-64 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HEOGLLMH_01330 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HEOGLLMH_01331 7.3e-155 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HEOGLLMH_01332 1.1e-85 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HEOGLLMH_01333 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
HEOGLLMH_01334 2.4e-120 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
HEOGLLMH_01335 5.6e-98 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
HEOGLLMH_01336 2.3e-287 ahpF O Alkyl hydroperoxide reductase
HEOGLLMH_01337 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
HEOGLLMH_01338 3.6e-128 E Ring-cleavage extradiol dioxygenase
HEOGLLMH_01339 4.5e-74 yxaI S membrane protein domain
HEOGLLMH_01340 1.5e-203 EGP Major facilitator Superfamily
HEOGLLMH_01341 2.3e-50 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
HEOGLLMH_01342 3.9e-64 S Family of unknown function (DUF5391)
HEOGLLMH_01343 1.9e-85 S PQQ-like domain
HEOGLLMH_01344 2.9e-215 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HEOGLLMH_01345 8.5e-126 yxbF K Bacterial regulatory proteins, tetR family
HEOGLLMH_01346 1.1e-50 yxbF K Bacterial regulatory proteins, tetR family
HEOGLLMH_01347 4.5e-202 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HEOGLLMH_01348 1.8e-60 desK 2.7.13.3 T Histidine kinase
HEOGLLMH_01349 4.7e-129 desK 2.7.13.3 T Histidine kinase
HEOGLLMH_01350 1.2e-103 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEOGLLMH_01351 5.3e-150 IQ Enoyl-(Acyl carrier protein) reductase
HEOGLLMH_01352 0.0 htpG O Molecular chaperone. Has ATPase activity
HEOGLLMH_01353 6.7e-246 csbC EGP Major facilitator Superfamily
HEOGLLMH_01354 2.2e-81 iolS C Aldo keto reductase
HEOGLLMH_01355 7.1e-78 iolS C Aldo keto reductase
HEOGLLMH_01356 3.1e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
HEOGLLMH_01357 3.5e-274 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HEOGLLMH_01358 2.2e-156 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HEOGLLMH_01359 1.3e-87 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HEOGLLMH_01360 1e-81 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HEOGLLMH_01361 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HEOGLLMH_01362 9.4e-177 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HEOGLLMH_01363 1.1e-62 iolF EGP Major facilitator Superfamily
HEOGLLMH_01364 1e-148 iolF EGP Major facilitator Superfamily
HEOGLLMH_01365 6.1e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HEOGLLMH_01366 1.1e-166 iolH G Xylose isomerase-like TIM barrel
HEOGLLMH_01367 1.3e-148 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HEOGLLMH_01368 3.5e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HEOGLLMH_01369 1.8e-49 S ABC-2 family transporter protein
HEOGLLMH_01370 2.6e-14 S ABC-2 family transporter protein
HEOGLLMH_01371 2.7e-134 bcrA V ABC transporter, ATP-binding protein
HEOGLLMH_01372 5.3e-138 T Transcriptional regulator
HEOGLLMH_01373 5.6e-233 T Histidine kinase
HEOGLLMH_01374 9.3e-84 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEOGLLMH_01375 6.2e-24 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEOGLLMH_01376 1e-176 T PhoQ Sensor
HEOGLLMH_01377 5.5e-141 yxdL V ABC transporter, ATP-binding protein
HEOGLLMH_01378 0.0 yxdM V ABC transporter (permease)
HEOGLLMH_01379 2.6e-58 yxeA S Protein of unknown function (DUF1093)
HEOGLLMH_01380 4.9e-179 fhuD P Periplasmic binding protein
HEOGLLMH_01381 1.7e-12
HEOGLLMH_01382 8.4e-23 yxeD
HEOGLLMH_01383 4.3e-09 yxeE
HEOGLLMH_01386 1.8e-150 yidA S hydrolases of the HAD superfamily
HEOGLLMH_01387 1.1e-172 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HEOGLLMH_01388 9.4e-113 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HEOGLLMH_01389 2.3e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HEOGLLMH_01390 1.3e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
HEOGLLMH_01391 3.4e-253 lysP E amino acid
HEOGLLMH_01392 5e-176 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HEOGLLMH_01393 4.8e-235 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
HEOGLLMH_01394 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HEOGLLMH_01395 2.3e-287 hutH 4.3.1.3 E Histidine ammonia-lyase
HEOGLLMH_01396 7.7e-79 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HEOGLLMH_01397 1.6e-279 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HEOGLLMH_01398 1.1e-60 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HEOGLLMH_01399 0.0 L HKD family nuclease
HEOGLLMH_01400 4e-168 L HKD family nuclease
HEOGLLMH_01401 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HEOGLLMH_01402 7.1e-280 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HEOGLLMH_01403 9.8e-74 yxiE T Belongs to the universal stress protein A family
HEOGLLMH_01404 1.7e-116 yxxF EG EamA-like transporter family
HEOGLLMH_01405 3.8e-201 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
HEOGLLMH_01407 2.3e-31 yxiG
HEOGLLMH_01412 5.1e-15 S YxiJ-like protein
HEOGLLMH_01413 1.5e-21
HEOGLLMH_01415 4.5e-261 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HEOGLLMH_01416 5.4e-223 yxiO S COG2270 Permeases of the major facilitator superfamily
HEOGLLMH_01417 1e-148 licT K transcriptional antiterminator
HEOGLLMH_01418 6.6e-142 exoK GH16 M licheninase activity
HEOGLLMH_01419 1.6e-169 citH C Citrate transporter
HEOGLLMH_01420 3.6e-37 citH C Citrate transporter
HEOGLLMH_01421 3.6e-249 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
HEOGLLMH_01422 7.4e-118 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
HEOGLLMH_01423 4e-50 yxiS
HEOGLLMH_01424 6.6e-74 T Domain of unknown function (DUF4163)
HEOGLLMH_01425 1.7e-73 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HEOGLLMH_01426 2.3e-120 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HEOGLLMH_01427 2e-163 rlmA 2.1.1.187 Q Methyltransferase domain
HEOGLLMH_01428 4.8e-218 yxjG 2.1.1.14 E Methionine synthase
HEOGLLMH_01429 1.8e-86 yxjI S LURP-one-related
HEOGLLMH_01432 6.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HEOGLLMH_01433 1.8e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HEOGLLMH_01434 9.1e-66 yxkC S Domain of unknown function (DUF4352)
HEOGLLMH_01435 6.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HEOGLLMH_01436 1.2e-163 lrp QT PucR C-terminal helix-turn-helix domain
HEOGLLMH_01437 7e-206 msmK P Belongs to the ABC transporter superfamily
HEOGLLMH_01438 7.8e-157 yxkH G Polysaccharide deacetylase
HEOGLLMH_01439 4.5e-215 cimH C COG3493 Na citrate symporter
HEOGLLMH_01440 1.4e-267 cydA 1.10.3.14 C oxidase, subunit
HEOGLLMH_01441 4.2e-189 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
HEOGLLMH_01442 2.1e-74 cydD V ATP-binding
HEOGLLMH_01443 2.2e-224 cydD V ATP-binding
HEOGLLMH_01444 5.9e-292 cydD V ATP-binding protein
HEOGLLMH_01445 1.2e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HEOGLLMH_01446 7.8e-146 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
HEOGLLMH_01447 1.4e-49 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
HEOGLLMH_01448 1.6e-193 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HEOGLLMH_01449 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HEOGLLMH_01450 1.1e-211 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HEOGLLMH_01451 1.2e-185 manA 5.3.1.8 G mannose-6-phosphate isomerase
HEOGLLMH_01452 2.7e-168 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
HEOGLLMH_01453 9e-183 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HEOGLLMH_01454 2.3e-76 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HEOGLLMH_01455 3.7e-230 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEOGLLMH_01456 3.5e-49 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
HEOGLLMH_01457 2e-49 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
HEOGLLMH_01458 1.1e-179 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HEOGLLMH_01459 6.5e-32 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HEOGLLMH_01460 1.7e-57 arsR K transcriptional
HEOGLLMH_01461 2.2e-162 cbrA3 P Periplasmic binding protein
HEOGLLMH_01462 6.1e-180 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEOGLLMH_01463 1.9e-108 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEOGLLMH_01464 2.5e-31 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEOGLLMH_01465 2e-62 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HEOGLLMH_01466 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
HEOGLLMH_01467 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
HEOGLLMH_01468 3.3e-250 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEOGLLMH_01469 2.8e-09 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
HEOGLLMH_01470 1.4e-31 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
HEOGLLMH_01471 1.2e-252 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HEOGLLMH_01472 1.7e-204 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HEOGLLMH_01473 1.8e-228 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HEOGLLMH_01474 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEOGLLMH_01475 3.7e-229 dltB M membrane protein involved in D-alanine export
HEOGLLMH_01476 2.1e-293 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEOGLLMH_01477 6.1e-12 S D-Ala-teichoic acid biosynthesis protein
HEOGLLMH_01478 1.3e-168 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HEOGLLMH_01479 2.9e-116 ywaC 2.7.6.5 S protein conserved in bacteria
HEOGLLMH_01480 1.1e-163 gspA M General stress
HEOGLLMH_01481 4.3e-266 epr 3.4.21.62 O Belongs to the peptidase S8 family
HEOGLLMH_01482 1.3e-238 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEOGLLMH_01483 4.5e-67 ywbC 4.4.1.5 E glyoxalase
HEOGLLMH_01484 6.1e-224 ywbD 2.1.1.191 J Methyltransferase
HEOGLLMH_01485 3.8e-24 yjfC O Predicted Zn-dependent protease (DUF2268)
HEOGLLMH_01486 2e-64 yjfC O Predicted Zn-dependent protease (DUF2268)
HEOGLLMH_01487 3.5e-140 mta K transcriptional
HEOGLLMH_01488 1.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
HEOGLLMH_01489 1.5e-110 ywbG M effector of murein hydrolase
HEOGLLMH_01490 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HEOGLLMH_01491 8.2e-152 ywbI K Transcriptional regulator
HEOGLLMH_01492 1.6e-135 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HEOGLLMH_01493 1.7e-79 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HEOGLLMH_01494 1.1e-242 ywbN P Dyp-type peroxidase family protein
HEOGLLMH_01495 4.6e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HEOGLLMH_01496 2.7e-114 S Streptomycin biosynthesis protein StrF
HEOGLLMH_01497 9.5e-129 H Methionine biosynthesis protein MetW
HEOGLLMH_01499 1.3e-111 ywcC K Bacterial regulatory proteins, tetR family
HEOGLLMH_01500 7.8e-62 gtcA S GtrA-like protein
HEOGLLMH_01501 6.7e-167 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HEOGLLMH_01502 1.1e-294 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HEOGLLMH_01503 8.4e-27 ywzA S membrane
HEOGLLMH_01504 8.3e-179 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HEOGLLMH_01505 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HEOGLLMH_01506 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HEOGLLMH_01507 2e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HEOGLLMH_01508 3e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
HEOGLLMH_01509 5e-60 ysnE K acetyltransferase
HEOGLLMH_01511 9.9e-117 rodA D Belongs to the SEDS family
HEOGLLMH_01512 8e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
HEOGLLMH_01513 1.5e-183 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEOGLLMH_01514 9.1e-220 vpr O Belongs to the peptidase S8 family
HEOGLLMH_01515 1.4e-207 vpr O Belongs to the peptidase S8 family
HEOGLLMH_01517 8.3e-151 sacT K transcriptional antiterminator
HEOGLLMH_01518 2e-07 sacT K transcriptional antiterminator
HEOGLLMH_01519 3.6e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HEOGLLMH_01520 7.1e-283 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
HEOGLLMH_01521 1.3e-18 ywdA
HEOGLLMH_01522 6e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HEOGLLMH_01523 6.3e-57 pex K Transcriptional regulator PadR-like family
HEOGLLMH_01524 6.9e-89 ywdD
HEOGLLMH_01526 1.3e-151 ywdF GT2,GT4 S Glycosyltransferase like family 2
HEOGLLMH_01527 3.7e-133 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HEOGLLMH_01528 4.7e-41 ywdI S Family of unknown function (DUF5327)
HEOGLLMH_01529 1.3e-208 ywdJ F Xanthine uracil
HEOGLLMH_01530 1.6e-45 ywdK S small membrane protein
HEOGLLMH_01531 2e-45 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HEOGLLMH_01532 1.5e-15 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HEOGLLMH_01533 3.4e-143 spsA M Spore Coat
HEOGLLMH_01534 1.9e-138 spsB M Capsule polysaccharide biosynthesis protein
HEOGLLMH_01535 5.1e-223 spsC E Belongs to the DegT DnrJ EryC1 family
HEOGLLMH_01536 2e-160 spsD 2.3.1.210 K Spore Coat
HEOGLLMH_01537 6.4e-215 spsE 2.5.1.56 M acid synthase
HEOGLLMH_01538 4.4e-135 spsF M Spore Coat
HEOGLLMH_01539 6e-188 spsG M Spore Coat
HEOGLLMH_01540 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HEOGLLMH_01541 7.9e-182 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HEOGLLMH_01542 2.8e-162 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HEOGLLMH_01543 3.5e-87 spsL 5.1.3.13 M Spore Coat
HEOGLLMH_01544 7.1e-59
HEOGLLMH_01545 9.5e-247 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HEOGLLMH_01546 1e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HEOGLLMH_01547 3.3e-269 rocB E arginine degradation protein
HEOGLLMH_01548 3.7e-260 lysP E amino acid
HEOGLLMH_01549 3.1e-111 tcaB EGP Major facilitator Superfamily
HEOGLLMH_01550 7.2e-76 tcaB EGP Major facilitator Superfamily
HEOGLLMH_01551 2.2e-137 ywfA EGP Major facilitator Superfamily
HEOGLLMH_01552 2.2e-73 ywfA EGP Major facilitator Superfamily
HEOGLLMH_01553 1.1e-112 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HEOGLLMH_01554 3.4e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HEOGLLMH_01555 4.6e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEOGLLMH_01556 4.4e-269 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HEOGLLMH_01557 6.1e-208 bacE EGP Major facilitator Superfamily
HEOGLLMH_01558 4.6e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
HEOGLLMH_01559 1.3e-140 IQ Enoyl-(Acyl carrier protein) reductase
HEOGLLMH_01560 9.6e-146 ywfI C May function as heme-dependent peroxidase
HEOGLLMH_01561 1.9e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
HEOGLLMH_01562 6.2e-158 MA20_14895 S Conserved hypothetical protein 698
HEOGLLMH_01563 3e-162 cysL K Transcriptional regulator
HEOGLLMH_01564 7.7e-160 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HEOGLLMH_01565 1.8e-178
HEOGLLMH_01568 2.9e-168 yhcI S ABC transporter (permease)
HEOGLLMH_01569 3.5e-166 V ABC transporter, ATP-binding protein
HEOGLLMH_01570 1.4e-93 S membrane
HEOGLLMH_01571 8.2e-51 padR K PadR family transcriptional regulator
HEOGLLMH_01572 1.9e-109 rsfA_1
HEOGLLMH_01573 6.9e-36 ywzC S Belongs to the UPF0741 family
HEOGLLMH_01574 7.4e-255 ywfO S COG1078 HD superfamily phosphohydrolases
HEOGLLMH_01575 3.3e-34 ywgA 2.1.1.72, 3.1.21.3
HEOGLLMH_01576 3.1e-30 ywgA 2.1.1.72, 3.1.21.3
HEOGLLMH_01577 1.8e-243 yhdG_1 E C-terminus of AA_permease
HEOGLLMH_01578 3.6e-70 ywhA K Transcriptional regulator
HEOGLLMH_01579 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
HEOGLLMH_01580 1.2e-117 ywhC S Peptidase family M50
HEOGLLMH_01581 1.4e-95 ywhD S YwhD family
HEOGLLMH_01582 2.5e-82
HEOGLLMH_01583 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HEOGLLMH_01584 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HEOGLLMH_01585 7.8e-151 speB 3.5.3.11 E Belongs to the arginase family
HEOGLLMH_01588 1.3e-40 CP Membrane
HEOGLLMH_01590 2e-28 S Domain of unknown function (DUF4177)
HEOGLLMH_01591 1e-32
HEOGLLMH_01593 2.2e-32 S aspartate phosphatase
HEOGLLMH_01594 3.3e-32 S aspartate phosphatase
HEOGLLMH_01595 1.5e-221 ywhK CO amine dehydrogenase activity
HEOGLLMH_01596 2.4e-227 ywhL CO amine dehydrogenase activity
HEOGLLMH_01598 1.2e-73 ywiB S protein conserved in bacteria
HEOGLLMH_01599 1.7e-218 argS 6.1.1.19 J Arginyl-tRNA synthetase
HEOGLLMH_01600 2.9e-93 argS 6.1.1.19 J Arginyl-tRNA synthetase
HEOGLLMH_01601 5.8e-214 narK P COG2223 Nitrate nitrite transporter
HEOGLLMH_01602 3.1e-84 fnr K helix_turn_helix, cAMP Regulatory protein
HEOGLLMH_01603 1.6e-101 ywiC S YwiC-like protein
HEOGLLMH_01604 7.7e-85 arfM T cyclic nucleotide binding
HEOGLLMH_01605 3.1e-56 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEOGLLMH_01606 1.5e-299 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEOGLLMH_01607 9.2e-308 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEOGLLMH_01608 5.1e-74 narH 1.7.5.1 C Nitrate reductase, beta
HEOGLLMH_01609 1.2e-210 narH 1.7.5.1 C Nitrate reductase, beta
HEOGLLMH_01610 3.1e-36 narJ 1.7.5.1 C nitrate reductase
HEOGLLMH_01611 9.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
HEOGLLMH_01612 1.8e-105 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HEOGLLMH_01613 3.9e-44 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEOGLLMH_01614 1.3e-44 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEOGLLMH_01615 2.2e-122 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEOGLLMH_01616 7.1e-22 ywjA V ABC transporter
HEOGLLMH_01617 4.1e-289 ywjA V ABC transporter
HEOGLLMH_01618 1e-11 ywjC
HEOGLLMH_01619 2.8e-14 ywjC
HEOGLLMH_01620 1.8e-181 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HEOGLLMH_01621 1.6e-219 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HEOGLLMH_01622 0.0 fadF C COG0247 Fe-S oxidoreductase
HEOGLLMH_01623 6.1e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HEOGLLMH_01624 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HEOGLLMH_01625 1.7e-93 ywjG S Domain of unknown function (DUF2529)
HEOGLLMH_01626 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
HEOGLLMH_01627 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
HEOGLLMH_01628 6.4e-111 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HEOGLLMH_01629 5.1e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEOGLLMH_01630 2.8e-160 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
HEOGLLMH_01631 2.1e-210 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HEOGLLMH_01632 1.1e-32 rpmE J Binds the 23S rRNA
HEOGLLMH_01633 3.1e-104 tdk 2.7.1.21 F thymidine kinase
HEOGLLMH_01634 0.0 sfcA 1.1.1.38 C malic enzyme
HEOGLLMH_01635 3.6e-158 ywkB S Membrane transport protein
HEOGLLMH_01636 4.2e-90 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HEOGLLMH_01637 1.2e-67 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEOGLLMH_01638 1.9e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HEOGLLMH_01639 1.2e-123 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HEOGLLMH_01641 1.4e-60 ywlA S Uncharacterised protein family (UPF0715)
HEOGLLMH_01642 8.9e-119 spoIIR S stage II sporulation protein R
HEOGLLMH_01643 3.6e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
HEOGLLMH_01644 1.1e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HEOGLLMH_01645 4.5e-84 mntP P Probably functions as a manganese efflux pump
HEOGLLMH_01646 4.3e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HEOGLLMH_01647 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
HEOGLLMH_01648 5.9e-97 ywlG S Belongs to the UPF0340 family
HEOGLLMH_01649 8.7e-96 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HEOGLLMH_01650 1.4e-121 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HEOGLLMH_01651 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HEOGLLMH_01652 2.6e-13 atpI S ATP synthase
HEOGLLMH_01653 4.8e-32 atpI S ATP synthase
HEOGLLMH_01654 2.1e-129 atpB C it plays a direct role in the translocation of protons across the membrane
HEOGLLMH_01655 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEOGLLMH_01656 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HEOGLLMH_01657 6.1e-22 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEOGLLMH_01658 6.6e-51 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEOGLLMH_01659 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HEOGLLMH_01660 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HEOGLLMH_01661 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HEOGLLMH_01662 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HEOGLLMH_01663 1.2e-90 ywmA
HEOGLLMH_01664 1.3e-32 ywzB S membrane
HEOGLLMH_01665 9.7e-135 ywmB S TATA-box binding
HEOGLLMH_01666 4.7e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEOGLLMH_01667 3e-187 spoIID D Stage II sporulation protein D
HEOGLLMH_01668 1.2e-123 ywmC S protein containing a von Willebrand factor type A (vWA) domain
HEOGLLMH_01669 7.8e-123 ywmD S protein containing a von Willebrand factor type A (vWA) domain
HEOGLLMH_01671 1.4e-144 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HEOGLLMH_01672 1.8e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HEOGLLMH_01673 1.5e-94 S response regulator aspartate phosphatase
HEOGLLMH_01674 2.1e-82 ywmF S Peptidase M50
HEOGLLMH_01675 3.3e-10 csbD K CsbD-like
HEOGLLMH_01676 5.4e-50 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HEOGLLMH_01677 1.9e-62 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HEOGLLMH_01678 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HEOGLLMH_01679 6.1e-67 ywnA K Transcriptional regulator
HEOGLLMH_01681 9e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
HEOGLLMH_01682 4.4e-54 ywnC S Family of unknown function (DUF5362)
HEOGLLMH_01683 3.7e-257 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEOGLLMH_01684 4.2e-69 ywnF S Family of unknown function (DUF5392)
HEOGLLMH_01685 4.1e-11 ywnC S Family of unknown function (DUF5362)
HEOGLLMH_01686 4.9e-90 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
HEOGLLMH_01687 4.9e-122 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
HEOGLLMH_01688 2.1e-70 ywnJ S VanZ like family
HEOGLLMH_01689 5.4e-101 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
HEOGLLMH_01690 1.4e-209 ftsW D Belongs to the SEDS family
HEOGLLMH_01691 2e-58 nrgB K Belongs to the P(II) protein family
HEOGLLMH_01692 2.5e-228 amt P Ammonium transporter
HEOGLLMH_01693 1.3e-102 phzA Q Isochorismatase family
HEOGLLMH_01694 2.8e-81 ywoD EGP Major facilitator superfamily
HEOGLLMH_01695 3.3e-144 ywoD EGP Major facilitator superfamily
HEOGLLMH_01696 5e-276 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
HEOGLLMH_01697 3.8e-213 ywoG EGP Major facilitator Superfamily
HEOGLLMH_01698 8.5e-72 ywoH K transcriptional
HEOGLLMH_01699 1.8e-44 spoIIID K Stage III sporulation protein D
HEOGLLMH_01700 2.7e-180 mbl D Rod shape-determining protein
HEOGLLMH_01701 3.2e-128 flhO N flagellar basal body
HEOGLLMH_01702 7.4e-144 flhP N flagellar basal body
HEOGLLMH_01703 1e-198 S aspartate phosphatase
HEOGLLMH_01704 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HEOGLLMH_01705 1.1e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HEOGLLMH_01706 3.9e-69 ywpF S YwpF-like protein
HEOGLLMH_01707 3.7e-58 ywpG
HEOGLLMH_01708 1.3e-57 ssbB L Single-stranded DNA-binding protein
HEOGLLMH_01709 3.7e-137 glcR K DeoR C terminal sensor domain
HEOGLLMH_01710 3e-156 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
HEOGLLMH_01711 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HEOGLLMH_01712 9.4e-136 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HEOGLLMH_01713 1.2e-307 ywqB S SWIM zinc finger
HEOGLLMH_01714 1.3e-14
HEOGLLMH_01715 5.2e-112 ywqC M biosynthesis protein
HEOGLLMH_01716 1.4e-113 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
HEOGLLMH_01717 1.1e-116 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
HEOGLLMH_01718 1.2e-247 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HEOGLLMH_01719 3.9e-150 ywqG S Domain of unknown function (DUF1963)
HEOGLLMH_01721 1e-20 S Domain of unknown function (DUF5082)
HEOGLLMH_01722 4.3e-37 ywqI S Family of unknown function (DUF5344)
HEOGLLMH_01723 4.4e-33 ywqJ S Pre-toxin TG
HEOGLLMH_01724 3.5e-219 ywqJ S Pre-toxin TG
HEOGLLMH_01725 2e-49
HEOGLLMH_01727 2e-61 S Protein of unknown function (DUF2004)
HEOGLLMH_01728 1.4e-70 ywqJ S Pre-toxin TG
HEOGLLMH_01729 1.1e-33 fliD N LXG domain of WXG superfamily
HEOGLLMH_01730 5.3e-65
HEOGLLMH_01731 1.1e-55
HEOGLLMH_01732 8.4e-136 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HEOGLLMH_01733 4.4e-89 ywrA P COG2059 Chromate transport protein ChrA
HEOGLLMH_01734 2e-103 ywrB P Chromate transporter
HEOGLLMH_01735 1.1e-83 ywrC K Transcriptional regulator
HEOGLLMH_01736 6.1e-304 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HEOGLLMH_01737 3.6e-07 S Domain of unknown function (DUF4181)
HEOGLLMH_01738 2.5e-112 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HEOGLLMH_01739 2.6e-09
HEOGLLMH_01740 3.8e-212 cotH M Spore Coat
HEOGLLMH_01741 6.1e-125 cotB
HEOGLLMH_01742 4.4e-126 ywrJ
HEOGLLMH_01743 6.2e-241 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HEOGLLMH_01744 9e-167 alsR K LysR substrate binding domain
HEOGLLMH_01745 2.4e-309 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HEOGLLMH_01746 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
HEOGLLMH_01747 1.1e-95 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
HEOGLLMH_01748 5.2e-90 batE T Sh3 type 3 domain protein
HEOGLLMH_01749 5.7e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
HEOGLLMH_01750 2.9e-155 rbsC G Belongs to the binding-protein-dependent transport system permease family
HEOGLLMH_01751 2.4e-278 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HEOGLLMH_01752 1.1e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HEOGLLMH_01753 2.7e-103 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEOGLLMH_01754 6.5e-43 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEOGLLMH_01755 3.6e-177 rbsR K transcriptional
HEOGLLMH_01756 1.4e-204 gerKC S Spore germination B3/ GerAC like, C-terminal
HEOGLLMH_01757 1e-191 gerKB E Spore germination protein
HEOGLLMH_01758 1.8e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
HEOGLLMH_01759 2.3e-70 pgsC S biosynthesis protein
HEOGLLMH_01760 3.6e-217 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HEOGLLMH_01761 9.8e-241 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HEOGLLMH_01763 4.2e-158 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
HEOGLLMH_01764 3.8e-179 ywtF K Transcriptional regulator
HEOGLLMH_01765 3.7e-249 ywtG EGP Major facilitator Superfamily
HEOGLLMH_01766 7.5e-266 GT2,GT4 J Glycosyl transferase family 2
HEOGLLMH_01767 9.3e-214 gerAC S Spore germination protein
HEOGLLMH_01768 1.7e-199 gerBB E Spore germination protein
HEOGLLMH_01769 1e-265 gerBA EG Spore germination protein
HEOGLLMH_01770 4.8e-187 pmi 5.3.1.8 G mannose-6-phosphate isomerase
HEOGLLMH_01771 1.7e-242 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HEOGLLMH_01772 1.5e-86 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HEOGLLMH_01773 3.7e-115 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HEOGLLMH_01774 5.9e-143 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HEOGLLMH_01775 7.7e-19 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
HEOGLLMH_01776 5.8e-277 M Glycosyltransferase like family 2
HEOGLLMH_01777 4.5e-94 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HEOGLLMH_01778 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HEOGLLMH_01779 1.7e-151 tagG GM Transport permease protein
HEOGLLMH_01780 4e-284 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HEOGLLMH_01781 2.4e-115 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HEOGLLMH_01782 5.4e-31 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HEOGLLMH_01783 1.4e-66 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HEOGLLMH_01784 4.7e-22 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HEOGLLMH_01785 9.3e-95 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HEOGLLMH_01786 1e-41 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HEOGLLMH_01787 4e-92 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HEOGLLMH_01788 5.9e-49
HEOGLLMH_01789 5e-163 lytB 3.5.1.28 D Stage II sporulation protein
HEOGLLMH_01790 3.9e-170 lytB 3.5.1.28 D Stage II sporulation protein
HEOGLLMH_01791 1.7e-42 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HEOGLLMH_01792 3.1e-212 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HEOGLLMH_01793 5.2e-48 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HEOGLLMH_01794 2.5e-58 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HEOGLLMH_01795 1e-257 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEOGLLMH_01796 1.4e-223 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
HEOGLLMH_01797 6.6e-251 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HEOGLLMH_01798 5.5e-256 tuaE M Teichuronic acid biosynthesis protein
HEOGLLMH_01799 9.2e-116 tuaF M protein involved in exopolysaccharide biosynthesis
HEOGLLMH_01800 1.3e-142 tuaG GT2 M Glycosyltransferase like family 2
HEOGLLMH_01801 5.2e-239 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
HEOGLLMH_01802 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HEOGLLMH_01803 1.1e-172 yvhJ K Transcriptional regulator
HEOGLLMH_01804 1.2e-70 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
HEOGLLMH_01805 6.2e-16 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
HEOGLLMH_01806 1.7e-181 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HEOGLLMH_01807 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEOGLLMH_01808 1.4e-158 degV S protein conserved in bacteria
HEOGLLMH_01809 5.1e-262 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HEOGLLMH_01810 1.5e-43 comFB S Late competence development protein ComFB
HEOGLLMH_01811 5.3e-78 comFC S Phosphoribosyl transferase domain
HEOGLLMH_01812 1.4e-74 yvyF S flagellar protein
HEOGLLMH_01813 8e-21 flgM KNU Negative regulator of flagellin synthesis
HEOGLLMH_01814 8.9e-81 flgN NOU FlgN protein
HEOGLLMH_01815 3.7e-274 flgK N flagellar hook-associated protein
HEOGLLMH_01816 6.1e-163 flgL N Belongs to the bacterial flagellin family
HEOGLLMH_01817 1.4e-80 yviE
HEOGLLMH_01818 8.5e-75 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HEOGLLMH_01819 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HEOGLLMH_01820 2.1e-114 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HEOGLLMH_01821 9.6e-262 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HEOGLLMH_01822 3e-66 fliS N flagellar protein FliS
HEOGLLMH_01823 9.1e-11 fliT S bacterial-type flagellum organization
HEOGLLMH_01824 2e-67
HEOGLLMH_01825 1.1e-101 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HEOGLLMH_01826 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HEOGLLMH_01827 1.4e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HEOGLLMH_01829 9.5e-52 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
HEOGLLMH_01830 1e-57 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
HEOGLLMH_01831 1e-122 ftsE D cell division ATP-binding protein FtsE
HEOGLLMH_01832 3.5e-23 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HEOGLLMH_01833 1.9e-69 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HEOGLLMH_01834 5.6e-43 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HEOGLLMH_01835 2.6e-45 ywoF P Right handed beta helix region
HEOGLLMH_01836 2.9e-170 ywoF P Right handed beta helix region
HEOGLLMH_01837 5.1e-79 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
HEOGLLMH_01838 1.2e-86 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
HEOGLLMH_01839 1.3e-28 swrA S Swarming motility protein
HEOGLLMH_01840 9e-209 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEOGLLMH_01841 1.2e-121 S Psort location CytoplasmicMembrane, score
HEOGLLMH_01842 1.5e-30 bacT Q Thioesterase domain
HEOGLLMH_01843 4.3e-08 bacT Q PFAM Thioesterase
HEOGLLMH_01845 1.1e-226 yvkA EGP Major facilitator Superfamily
HEOGLLMH_01846 2.4e-110 yvkB K Transcriptional regulator
HEOGLLMH_01847 0.0 yvkC 2.7.9.2 GT Phosphotransferase
HEOGLLMH_01848 7.6e-33 csbA S protein conserved in bacteria
HEOGLLMH_01849 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HEOGLLMH_01850 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HEOGLLMH_01851 9.6e-35 yvkN
HEOGLLMH_01852 7e-166 yvlB S Putative adhesin
HEOGLLMH_01853 9.6e-26 pspB KT PspC domain
HEOGLLMH_01854 3.9e-41 yvlD S Membrane
HEOGLLMH_01855 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
HEOGLLMH_01856 3.9e-77 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
HEOGLLMH_01857 4e-104 yxaF K Transcriptional regulator
HEOGLLMH_01858 1.1e-133 yvoA K transcriptional
HEOGLLMH_01859 6.1e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HEOGLLMH_01860 3.9e-33 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HEOGLLMH_01861 2.1e-129 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HEOGLLMH_01862 1.5e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HEOGLLMH_01863 1.2e-151 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HEOGLLMH_01864 3.8e-71 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HEOGLLMH_01865 7.6e-24 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HEOGLLMH_01866 1.6e-83 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
HEOGLLMH_01867 9.1e-138 yvpB NU protein conserved in bacteria
HEOGLLMH_01868 6.1e-208 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HEOGLLMH_01869 2.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HEOGLLMH_01870 8.5e-235 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HEOGLLMH_01871 8.8e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HEOGLLMH_01872 5.6e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HEOGLLMH_01873 3.8e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HEOGLLMH_01874 4e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HEOGLLMH_01875 3.7e-111 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
HEOGLLMH_01876 0.0 msbA2 3.6.3.44 V ABC transporter
HEOGLLMH_01877 5e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEOGLLMH_01878 3.2e-192 sasA T Histidine kinase
HEOGLLMH_01879 4.2e-275 S COG0457 FOG TPR repeat
HEOGLLMH_01880 4.3e-114 usp CBM50 M protein conserved in bacteria
HEOGLLMH_01881 3.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HEOGLLMH_01882 1.3e-61 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HEOGLLMH_01883 1.3e-10 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HEOGLLMH_01884 1.1e-166 rapZ S Displays ATPase and GTPase activities
HEOGLLMH_01885 1.7e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HEOGLLMH_01886 3.1e-170 whiA K May be required for sporulation
HEOGLLMH_01887 4.7e-36 crh G Phosphocarrier protein Chr
HEOGLLMH_01888 2.6e-143 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
HEOGLLMH_01889 6e-79 M Ribonuclease
HEOGLLMH_01890 3.3e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEOGLLMH_01891 7.4e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HEOGLLMH_01892 3.9e-282 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
HEOGLLMH_01893 7.3e-33 yvdC S MazG nucleotide pyrophosphohydrolase domain
HEOGLLMH_01895 3.4e-103 yvdD 3.2.2.10 S Belongs to the LOG family
HEOGLLMH_01896 1.6e-161 yvdE K Transcriptional regulator
HEOGLLMH_01897 1.1e-309 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
HEOGLLMH_01898 1.2e-206 mdxE G COG2182 Maltose-binding periplasmic proteins domains
HEOGLLMH_01899 8.3e-222 malC P COG1175 ABC-type sugar transport systems, permease components
HEOGLLMH_01900 1.7e-140 malD P transport
HEOGLLMH_01901 3.7e-109 malA S Protein of unknown function (DUF1189)
HEOGLLMH_01902 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
HEOGLLMH_01903 9.4e-127 malL 3.2.1.10 GH13 G COG0366 Glycosidases
HEOGLLMH_01905 1.3e-146 malL 3.2.1.10 GH13 G COG0366 Glycosidases
HEOGLLMH_01906 1.4e-95 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
HEOGLLMH_01907 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HEOGLLMH_01908 5.1e-184 scrR K transcriptional
HEOGLLMH_01909 7.3e-220 rafB P LacY proton/sugar symporter
HEOGLLMH_01910 3.5e-120 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
HEOGLLMH_01911 1.2e-158 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
HEOGLLMH_01913 9.6e-23
HEOGLLMH_01914 6.4e-268 I Pfam Lipase (class 3)
HEOGLLMH_01916 9.3e-47 I Pfam Lipase (class 3)
HEOGLLMH_01917 8.5e-38 S Protein of unknown function (DUF1433)
HEOGLLMH_01918 2.9e-15 S Protein of unknown function (DUF1433)
HEOGLLMH_01919 8.8e-54 MA20_18690 S Protein of unknown function (DUF3237)
HEOGLLMH_01920 5.5e-94 padC Q Phenolic acid decarboxylase
HEOGLLMH_01921 3.2e-71 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEOGLLMH_01922 5.7e-112 yyaS S Membrane
HEOGLLMH_01923 2.6e-88 ywjB H RibD C-terminal domain
HEOGLLMH_01924 2.2e-284 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
HEOGLLMH_01925 1.9e-77 slr K transcriptional
HEOGLLMH_01926 4e-67 ywqC M biosynthesis protein
HEOGLLMH_01927 8.5e-41 ywqC M biosynthesis protein
HEOGLLMH_01928 6.5e-115 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
HEOGLLMH_01929 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
HEOGLLMH_01930 3.9e-220 epsD GT4 M Glycosyl transferase 4-like
HEOGLLMH_01931 1.8e-161 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HEOGLLMH_01932 1.4e-212 epsF GT4 M Glycosyl transferases group 1
HEOGLLMH_01933 3.5e-205 epsG S EpsG family
HEOGLLMH_01934 1.4e-195 epsH GT2 S Glycosyltransferase like family 2
HEOGLLMH_01935 5.2e-206 epsI GM pyruvyl transferase
HEOGLLMH_01936 2.2e-177 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
HEOGLLMH_01937 2.8e-30 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEOGLLMH_01938 4.9e-213 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEOGLLMH_01939 9.8e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HEOGLLMH_01940 9.6e-54 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
HEOGLLMH_01941 4.1e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HEOGLLMH_01942 6.8e-189 yvfF GM Exopolysaccharide biosynthesis protein
HEOGLLMH_01943 2.7e-32 yvfG S YvfG protein
HEOGLLMH_01944 9.1e-245 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HEOGLLMH_01945 9.4e-287 yvfH C L-lactate permease
HEOGLLMH_01946 1.1e-119 yvfI K COG2186 Transcriptional regulators
HEOGLLMH_01947 2.8e-224 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEOGLLMH_01948 1.7e-64 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HEOGLLMH_01949 8.9e-59 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HEOGLLMH_01950 1.8e-270 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HEOGLLMH_01951 6.7e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HEOGLLMH_01952 2.1e-225 gntP EG COG2610 H gluconate symporter and related permeases
HEOGLLMH_01953 3.2e-297 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
HEOGLLMH_01954 2.2e-151 ybbH_1 K RpiR family transcriptional regulator
HEOGLLMH_01956 2.2e-103 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
HEOGLLMH_01957 3.5e-113 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
HEOGLLMH_01958 7.7e-158 yvbV EG EamA-like transporter family
HEOGLLMH_01959 3.5e-78 yvbU K Transcriptional regulator
HEOGLLMH_01960 5.6e-41 yvbU K Transcriptional regulator
HEOGLLMH_01962 5.6e-135 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEOGLLMH_01963 1.3e-204 araR K transcriptional
HEOGLLMH_01964 1.1e-218 araE EGP Major facilitator Superfamily
HEOGLLMH_01966 2.3e-187 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HEOGLLMH_01967 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HEOGLLMH_01968 5.1e-09 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HEOGLLMH_01969 6.2e-146 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HEOGLLMH_01970 4.2e-08 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HEOGLLMH_01971 1.1e-26 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HEOGLLMH_01972 4.8e-102 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HEOGLLMH_01973 3.7e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
HEOGLLMH_01974 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HEOGLLMH_01975 3.7e-101 ywaD 3.4.11.10, 3.4.11.6 S PA domain
HEOGLLMH_01976 4e-86 ywaD 3.4.11.10, 3.4.11.6 S PA domain
HEOGLLMH_01977 5.1e-57 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HEOGLLMH_01978 2.4e-192 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HEOGLLMH_01979 1.3e-218 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HEOGLLMH_01980 6.2e-171 5.1.3.2 M GDP-mannose 4,6 dehydratase
HEOGLLMH_01981 2.5e-34 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HEOGLLMH_01982 1.4e-90 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HEOGLLMH_01983 1e-115 M Protein involved in cellulose biosynthesis
HEOGLLMH_01984 1.3e-90 C WbqC-like protein family
HEOGLLMH_01985 1.5e-49 C WbqC-like protein family
HEOGLLMH_01986 1.4e-124 S GlcNAc-PI de-N-acetylase
HEOGLLMH_01987 1.6e-179
HEOGLLMH_01988 2.3e-213 EGP Major facilitator Superfamily
HEOGLLMH_01989 5.3e-64 yvbK 3.1.3.25 K acetyltransferase
HEOGLLMH_01990 5.4e-256 tcaA S response to antibiotic
HEOGLLMH_01991 1e-57 tcaA S response to antibiotic
HEOGLLMH_01992 6.2e-115 exoY M Membrane
HEOGLLMH_01993 5.2e-105 yvbG U UPF0056 membrane protein
HEOGLLMH_01994 5.4e-87 yvbF K Belongs to the GbsR family
HEOGLLMH_01995 6.7e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HEOGLLMH_01996 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HEOGLLMH_01997 9.4e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HEOGLLMH_01998 2.8e-109 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HEOGLLMH_01999 4.3e-76 yvbF K Belongs to the GbsR family
HEOGLLMH_02000 1.8e-209 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HEOGLLMH_02001 5.4e-113 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HEOGLLMH_02002 8.5e-173 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HEOGLLMH_02003 2.3e-111 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HEOGLLMH_02004 2.5e-127 mutF V ABC transporter, ATP-binding protein
HEOGLLMH_02005 3.4e-124 spaE S ABC-2 family transporter protein
HEOGLLMH_02006 1.8e-108 mutG S ABC-2 family transporter protein
HEOGLLMH_02007 2e-123 K Transcriptional regulatory protein, C terminal
HEOGLLMH_02008 1.2e-258 T His Kinase A (phosphoacceptor) domain
HEOGLLMH_02009 8.8e-53 yodB K transcriptional
HEOGLLMH_02010 2.3e-72 yvaO K Cro/C1-type HTH DNA-binding domain
HEOGLLMH_02011 1e-69 K transcriptional
HEOGLLMH_02012 6e-35 yvzC K Transcriptional
HEOGLLMH_02013 4.8e-24 secG U Preprotein translocase subunit SecG
HEOGLLMH_02014 7.4e-143 est 3.1.1.1 S Carboxylesterase
HEOGLLMH_02015 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HEOGLLMH_02016 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HEOGLLMH_02018 2.9e-53 yrdF K ribonuclease inhibitor
HEOGLLMH_02019 9.1e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HEOGLLMH_02020 2.5e-161 ytlI K LysR substrate binding domain
HEOGLLMH_02021 3e-101 ytmI K Acetyltransferase (GNAT) domain
HEOGLLMH_02022 6e-130 ytmJ ET Bacterial periplasmic substrate-binding proteins
HEOGLLMH_02023 1.1e-124 tcyK M Bacterial periplasmic substrate-binding proteins
HEOGLLMH_02024 2.6e-64 tcyL P Binding-protein-dependent transport system inner membrane component
HEOGLLMH_02025 3.3e-36 tcyL P Binding-protein-dependent transport system inner membrane component
HEOGLLMH_02026 6.4e-120 tcyM U Binding-protein-dependent transport system inner membrane component
HEOGLLMH_02027 9.5e-141 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HEOGLLMH_02028 5.4e-181 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEOGLLMH_02029 2.3e-47 ytnI O COG0695 Glutaredoxin and related proteins
HEOGLLMH_02030 1.2e-255 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEOGLLMH_02032 1.1e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HEOGLLMH_02033 1.8e-195 yvaA 1.1.1.371 S Oxidoreductase
HEOGLLMH_02034 3.7e-48 csoR S transcriptional
HEOGLLMH_02035 2.6e-29 copZ P Heavy-metal-associated domain
HEOGLLMH_02036 0.0 copA 3.6.3.54 P P-type ATPase
HEOGLLMH_02037 1.2e-47 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HEOGLLMH_02038 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HEOGLLMH_02039 1.2e-102 bdbD O Thioredoxin
HEOGLLMH_02040 6e-73 bdbC O Required for disulfide bond formation in some proteins
HEOGLLMH_02041 5.2e-142 S Metallo-peptidase family M12
HEOGLLMH_02042 3.1e-99 yvgT S membrane
HEOGLLMH_02043 3.2e-114 helD 3.6.4.12 L DNA helicase
HEOGLLMH_02044 4.1e-80 helD 3.6.4.12 L DNA helicase
HEOGLLMH_02045 4.5e-126 helD 3.6.4.12 L DNA helicase
HEOGLLMH_02046 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HEOGLLMH_02048 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HEOGLLMH_02049 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
HEOGLLMH_02050 1.3e-84 yvgO
HEOGLLMH_02051 5e-156 yvgN S reductase
HEOGLLMH_02052 3.5e-200 yfiN V COG0842 ABC-type multidrug transport system, permease component
HEOGLLMH_02053 1.3e-120 yfiM V ABC-2 type transporter
HEOGLLMH_02054 8.3e-35 yfiM V ABC-2 type transporter
HEOGLLMH_02055 1.9e-172 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
HEOGLLMH_02056 1e-180 T Histidine kinase
HEOGLLMH_02057 2.4e-113 yfiK K Regulator
HEOGLLMH_02058 7.9e-99 modB P COG4149 ABC-type molybdate transport system, permease component
HEOGLLMH_02059 1.4e-139 modA P COG0725 ABC-type molybdate transport system, periplasmic component
HEOGLLMH_02060 1.6e-166 yvgK P COG1910 Periplasmic molybdate-binding protein domain
HEOGLLMH_02061 1.6e-85 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HEOGLLMH_02062 2.6e-258 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HEOGLLMH_02063 1.3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
HEOGLLMH_02064 1e-13 S Small spore protein J (Spore_SspJ)
HEOGLLMH_02065 3.9e-233 yvsH E Arginine ornithine antiporter
HEOGLLMH_02066 1.4e-175 fhuD P ABC transporter
HEOGLLMH_02067 1.2e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEOGLLMH_02068 5.2e-165 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEOGLLMH_02069 4.8e-148 fhuC 3.6.3.34 HP ABC transporter
HEOGLLMH_02070 2.4e-66 yvrL S Regulatory protein YrvL
HEOGLLMH_02071 9.2e-233 oxdC 4.1.1.2 G Oxalate decarboxylase
HEOGLLMH_02072 1.6e-15 S YvrJ protein family
HEOGLLMH_02073 9.9e-103 yvrI K RNA polymerase
HEOGLLMH_02074 1.1e-36
HEOGLLMH_02075 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEOGLLMH_02076 7.2e-181 T PhoQ Sensor
HEOGLLMH_02077 5.6e-135 T PhoQ Sensor
HEOGLLMH_02078 1.9e-169 yvrE G SMP-30/Gluconolaconase/LRE-like region
HEOGLLMH_02079 1.1e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HEOGLLMH_02080 1.1e-167 yvrC P ABC transporter substrate-binding protein
HEOGLLMH_02081 5.7e-181 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEOGLLMH_02082 1e-226 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HEOGLLMH_02083 3.7e-102 yvqK 2.5.1.17 S Adenosyltransferase
HEOGLLMH_02084 8.8e-229 yvqJ EGP Major facilitator Superfamily
HEOGLLMH_02085 3.3e-46 liaI S membrane
HEOGLLMH_02086 1.5e-94 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HEOGLLMH_02087 5.5e-121 liaG S Putative adhesin
HEOGLLMH_02088 9.6e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
HEOGLLMH_02089 8.7e-193 vraS 2.7.13.3 T Histidine kinase
HEOGLLMH_02090 5.6e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEOGLLMH_02091 4.7e-210 gerAC S Spore germination B3/ GerAC like, C-terminal
HEOGLLMH_02092 3.8e-188 gerAB E Spore germination protein
HEOGLLMH_02093 4.9e-260 gerAA EG Spore germination protein
HEOGLLMH_02094 6.6e-24 S Protein of unknown function (DUF3970)
HEOGLLMH_02095 4.4e-14 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HEOGLLMH_02096 9.7e-236 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HEOGLLMH_02097 1e-157 yuxN K Transcriptional regulator
HEOGLLMH_02098 1.3e-23
HEOGLLMH_02099 5.7e-250 cssS 2.7.13.3 T PhoQ Sensor
HEOGLLMH_02100 2.6e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEOGLLMH_02101 1.7e-23 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEOGLLMH_02102 1.1e-70 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEOGLLMH_02103 6e-109 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEOGLLMH_02104 3.6e-79 dps P Belongs to the Dps family
HEOGLLMH_02105 4.1e-83 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HEOGLLMH_02106 1.6e-57 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HEOGLLMH_02107 0.0 pepF2 E COG1164 Oligoendopeptidase F
HEOGLLMH_02108 1e-43 S YusW-like protein
HEOGLLMH_02109 1.4e-150 yusV 3.6.3.34 HP ABC transporter
HEOGLLMH_02110 3.3e-39 yusU S Protein of unknown function (DUF2573)
HEOGLLMH_02111 3.9e-190 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HEOGLLMH_02112 1e-139 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
HEOGLLMH_02113 8.8e-159 ywbI2 K Transcriptional regulator
HEOGLLMH_02114 1.3e-48 yusP P Major facilitator superfamily
HEOGLLMH_02115 2e-217 yusP P Major facilitator superfamily
HEOGLLMH_02116 5.7e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
HEOGLLMH_02117 1.1e-53 yusN M Coat F domain
HEOGLLMH_02118 3.9e-43
HEOGLLMH_02119 8.1e-168 fadM E Proline dehydrogenase
HEOGLLMH_02121 7e-170 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
HEOGLLMH_02122 1.2e-266 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
HEOGLLMH_02123 1.6e-216 fadA 2.3.1.16 I Belongs to the thiolase family
HEOGLLMH_02124 1.5e-308 fadE 1.3.8.1 I acyl-CoA dehydrogenase
HEOGLLMH_02125 6.2e-63 arsC 1.20.4.1 P Belongs to the ArsC family
HEOGLLMH_02126 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HEOGLLMH_02127 3.7e-40 yusG S Protein of unknown function (DUF2553)
HEOGLLMH_02128 2.9e-57 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
HEOGLLMH_02129 1.6e-54 yusE CO Thioredoxin
HEOGLLMH_02130 5e-57 yusD S SCP-2 sterol transfer family
HEOGLLMH_02131 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HEOGLLMH_02132 1.8e-95 metI P COG2011 ABC-type metal ion transport system, permease component
HEOGLLMH_02133 2.3e-145 metQ P Belongs to the NlpA lipoprotein family
HEOGLLMH_02134 7.6e-64 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HEOGLLMH_02135 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HEOGLLMH_02136 7e-245 sufD O assembly protein SufD
HEOGLLMH_02137 2.1e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HEOGLLMH_02138 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
HEOGLLMH_02139 3e-270 sufB O FeS cluster assembly
HEOGLLMH_02140 1.3e-156 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HEOGLLMH_02141 2.7e-82 yncE S Protein of unknown function (DUF2691)
HEOGLLMH_02142 3.3e-124 Q ubiE/COQ5 methyltransferase family
HEOGLLMH_02143 6e-205 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
HEOGLLMH_02144 3.1e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
HEOGLLMH_02146 4.7e-185 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HEOGLLMH_02147 2.1e-168 yurO G COG1653 ABC-type sugar transport system, periplasmic component
HEOGLLMH_02148 2.8e-157 yurN G Binding-protein-dependent transport system inner membrane component
HEOGLLMH_02149 6.9e-164 yurM P COG0395 ABC-type sugar transport system, permease component
HEOGLLMH_02150 1.4e-161 yurL 2.7.1.218 G pfkB family carbohydrate kinase
HEOGLLMH_02151 1.2e-134 yurK K UTRA
HEOGLLMH_02152 5.7e-56 msmX P Belongs to the ABC transporter superfamily
HEOGLLMH_02153 1.6e-114 msmX P Belongs to the ABC transporter superfamily
HEOGLLMH_02154 2e-168 bsn L Ribonuclease
HEOGLLMH_02155 1.9e-236 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HEOGLLMH_02156 6.7e-237 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HEOGLLMH_02157 3.8e-213 blt EGP Major facilitator Superfamily
HEOGLLMH_02158 5.5e-37
HEOGLLMH_02159 4.2e-11
HEOGLLMH_02160 9.3e-32 yqbD 2.1.1.72 L Putative phage serine protease XkdF
HEOGLLMH_02161 4.7e-304 pucR QT COG2508 Regulator of polyketide synthase expression
HEOGLLMH_02162 5.3e-264 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HEOGLLMH_02163 1.5e-61 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
HEOGLLMH_02164 3.1e-169 yunF S Protein of unknown function DUF72
HEOGLLMH_02166 1.3e-131 yunE S membrane transporter protein
HEOGLLMH_02167 4.5e-266 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HEOGLLMH_02168 1.9e-130 yunB S Sporulation protein YunB (Spo_YunB)
HEOGLLMH_02169 3.8e-195 lytH M Peptidase, M23
HEOGLLMH_02170 2.5e-08 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HEOGLLMH_02171 6.8e-150 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HEOGLLMH_02172 1.7e-47 yutD S protein conserved in bacteria
HEOGLLMH_02173 1.9e-74 yutE S Protein of unknown function DUF86
HEOGLLMH_02174 3.6e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HEOGLLMH_02175 1.2e-55 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HEOGLLMH_02176 1.2e-196 yutH S Spore coat protein
HEOGLLMH_02177 6e-241 hom 1.1.1.3 E homoserine dehydrogenase
HEOGLLMH_02178 1.7e-196 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HEOGLLMH_02179 1.9e-167 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HEOGLLMH_02180 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
HEOGLLMH_02181 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
HEOGLLMH_02182 6.7e-56 yuzD S protein conserved in bacteria
HEOGLLMH_02183 9.4e-208 yutJ 1.6.99.3 C NADH dehydrogenase
HEOGLLMH_02184 2.4e-39 yuzB S Belongs to the UPF0349 family
HEOGLLMH_02185 9.3e-34 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HEOGLLMH_02186 1.6e-166 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HEOGLLMH_02187 5.7e-163 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HEOGLLMH_02188 4.1e-62 erpA S Belongs to the HesB IscA family
HEOGLLMH_02189 4.6e-120 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
HEOGLLMH_02190 5.6e-74 rimJ 2.3.1.128 J Alanine acetyltransferase
HEOGLLMH_02192 2.9e-33 S Bacteriocin class IId cyclical uberolysin-like
HEOGLLMH_02194 5.2e-30 V ABC transporter
HEOGLLMH_02195 5.2e-69 V ABC transporter
HEOGLLMH_02196 9.2e-71 CP Membrane
HEOGLLMH_02197 4.8e-29
HEOGLLMH_02198 1.6e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HEOGLLMH_02200 5e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
HEOGLLMH_02201 1.1e-236 yumB 1.6.99.3 C NADH dehydrogenase
HEOGLLMH_02202 9.9e-28 yuiB S Putative membrane protein
HEOGLLMH_02203 2e-97 yuiC S protein conserved in bacteria
HEOGLLMH_02204 2.6e-56 yuiD S protein conserved in bacteria
HEOGLLMH_02205 7.1e-08 yuiD S protein conserved in bacteria
HEOGLLMH_02206 2e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HEOGLLMH_02207 2.4e-208 yuiF S antiporter
HEOGLLMH_02208 7.7e-32 bioY S Biotin biosynthesis protein
HEOGLLMH_02209 1.9e-46 bioY S Biotin biosynthesis protein
HEOGLLMH_02210 1.2e-119 yuiH S Oxidoreductase molybdopterin binding domain
HEOGLLMH_02211 6.2e-165 besA S Putative esterase
HEOGLLMH_02212 4.6e-135 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HEOGLLMH_02213 5.6e-225 entC 5.4.4.2 HQ Isochorismate synthase
HEOGLLMH_02214 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
HEOGLLMH_02215 2.5e-172 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
HEOGLLMH_02216 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEOGLLMH_02217 1.3e-193 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEOGLLMH_02218 7.9e-50 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEOGLLMH_02219 1.3e-34 mbtH S MbtH-like protein
HEOGLLMH_02220 7.5e-134 yukJ S Uncharacterized conserved protein (DUF2278)
HEOGLLMH_02221 1e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
HEOGLLMH_02222 3.8e-229 yukF QT Transcriptional regulator
HEOGLLMH_02223 3.3e-46 esxA S Belongs to the WXG100 family
HEOGLLMH_02224 4.3e-39 yukD S WXG100 protein secretion system (Wss), protein YukD
HEOGLLMH_02225 2.9e-206 essB S WXG100 protein secretion system (Wss), protein YukC
HEOGLLMH_02226 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HEOGLLMH_02227 2.9e-235 esaA S type VII secretion protein EsaA
HEOGLLMH_02228 1e-13 esaA S type VII secretion protein EsaA
HEOGLLMH_02229 3.1e-176 esaA S type VII secretion protein EsaA
HEOGLLMH_02230 3e-128 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEOGLLMH_02231 3.7e-96 yueE S phosphohydrolase
HEOGLLMH_02232 1.6e-22 S Protein of unknown function (DUF2642)
HEOGLLMH_02233 1e-24 yueF S transporter activity
HEOGLLMH_02234 3.1e-151 yueF S transporter activity
HEOGLLMH_02235 6.4e-34 yueG S Spore germination protein gerPA/gerPF
HEOGLLMH_02236 7.2e-68 yueI S Protein of unknown function (DUF1694)
HEOGLLMH_02237 1.2e-102 pncA Q COG1335 Amidases related to nicotinamidase
HEOGLLMH_02238 8.8e-245 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HEOGLLMH_02239 1.3e-79 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
HEOGLLMH_02240 5.1e-133 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
HEOGLLMH_02241 4.7e-52 yuzC
HEOGLLMH_02243 1.2e-79 comQ H Polyprenyl synthetase
HEOGLLMH_02245 1.7e-13 comP 2.7.13.3 T Histidine kinase
HEOGLLMH_02246 5.3e-79 comP 2.7.13.3 T Histidine kinase
HEOGLLMH_02247 8e-126 comP 2.7.13.3 T Histidine kinase
HEOGLLMH_02248 1.8e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEOGLLMH_02249 3.2e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
HEOGLLMH_02250 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
HEOGLLMH_02251 1.1e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEOGLLMH_02252 5.3e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEOGLLMH_02253 1.5e-264 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEOGLLMH_02254 4.6e-16 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEOGLLMH_02255 1.8e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEOGLLMH_02256 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HEOGLLMH_02257 1.8e-12
HEOGLLMH_02258 1.6e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
HEOGLLMH_02259 1.1e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
HEOGLLMH_02260 8.6e-287 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HEOGLLMH_02261 1.2e-194 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HEOGLLMH_02262 2.7e-126 dcuR T COG4565 Response regulator of citrate malate metabolism
HEOGLLMH_02263 7.6e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HEOGLLMH_02264 2.1e-60 yufK S Family of unknown function (DUF5366)
HEOGLLMH_02265 2.2e-72 yuxK S protein conserved in bacteria
HEOGLLMH_02266 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
HEOGLLMH_02267 4.8e-150 yuxJ EGP Major facilitator Superfamily
HEOGLLMH_02268 1.2e-26 yuxJ EGP Major facilitator Superfamily
HEOGLLMH_02269 4e-118 kapD L the KinA pathway to sporulation
HEOGLLMH_02270 2e-67 kapB G Kinase associated protein B
HEOGLLMH_02271 6.7e-122 T PhoQ Sensor
HEOGLLMH_02272 3.8e-62 T PhoQ Sensor
HEOGLLMH_02273 4.5e-202 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HEOGLLMH_02274 2.4e-40 yugE S Domain of unknown function (DUF1871)
HEOGLLMH_02275 1.1e-155 yugF I Hydrolase
HEOGLLMH_02276 2e-83 alaR K Transcriptional regulator
HEOGLLMH_02277 6.5e-210 yugH 2.6.1.1 E Aminotransferase
HEOGLLMH_02278 6e-59 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
HEOGLLMH_02279 1.8e-34 yuzA S Domain of unknown function (DUF378)
HEOGLLMH_02280 1.2e-227 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
HEOGLLMH_02281 5.2e-215 yugK C Dehydrogenase
HEOGLLMH_02282 1e-50 ycaC Q Isochorismatase family
HEOGLLMH_02283 7.9e-51 ycaC Q Isochorismatase family
HEOGLLMH_02284 4.8e-51 S NADPH-dependent FMN reductase
HEOGLLMH_02285 1.9e-258 pgi 5.3.1.9 G Belongs to the GPI family
HEOGLLMH_02287 4.9e-72 yugN S YugN-like family
HEOGLLMH_02288 7e-181 yugO P COG1226 Kef-type K transport systems
HEOGLLMH_02289 6.7e-27 mstX S Membrane-integrating protein Mistic
HEOGLLMH_02290 7.7e-18
HEOGLLMH_02291 8.3e-117 yugP S Zn-dependent protease
HEOGLLMH_02292 7.3e-231 yugS S COG1253 Hemolysins and related proteins containing CBS domains
HEOGLLMH_02293 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
HEOGLLMH_02294 9.7e-76 yugU S Uncharacterised protein family UPF0047
HEOGLLMH_02295 5.6e-189 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HEOGLLMH_02296 1.1e-40
HEOGLLMH_02297 1.3e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
HEOGLLMH_02298 1.9e-133 mcpA NT chemotaxis protein
HEOGLLMH_02299 1.2e-65 mcpA NT chemotaxis protein
HEOGLLMH_02300 1.6e-237 mcpA NT chemotaxis protein
HEOGLLMH_02301 1.9e-225 mcpA NT chemotaxis protein
HEOGLLMH_02302 2.1e-237 mcpA NT chemotaxis protein
HEOGLLMH_02303 5.7e-97 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HEOGLLMH_02304 2.1e-185 ygjR S Oxidoreductase
HEOGLLMH_02305 7.6e-195 yubA S transporter activity
HEOGLLMH_02306 2.3e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HEOGLLMH_02308 1.9e-167 L Belongs to the 'phage' integrase family
HEOGLLMH_02309 4.4e-49 xkdA E IrrE N-terminal-like domain
HEOGLLMH_02310 1.7e-25 S Short C-terminal domain
HEOGLLMH_02311 3.7e-18 xre K Helix-turn-helix XRE-family like proteins
HEOGLLMH_02312 1.5e-17 K Helix-turn-helix domain
HEOGLLMH_02313 3.4e-15 S Helix-turn-helix domain
HEOGLLMH_02314 2.8e-46 S Phage regulatory protein Rha (Phage_pRha)
HEOGLLMH_02315 4.2e-85
HEOGLLMH_02319 2.4e-98
HEOGLLMH_02320 2.9e-68 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
HEOGLLMH_02322 3.7e-75 3.1.3.16 L DnaD domain protein
HEOGLLMH_02323 1.4e-122 xkdC L IstB-like ATP binding protein
HEOGLLMH_02326 4.2e-58 rusA L Endodeoxyribonuclease RusA
HEOGLLMH_02328 1.7e-17 yqaO S Phage-like element PBSX protein XtrA
HEOGLLMH_02330 4.3e-28
HEOGLLMH_02332 2.3e-105 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
HEOGLLMH_02334 6.9e-48
HEOGLLMH_02338 4.6e-67 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HEOGLLMH_02341 3.9e-12 K Transcriptional regulator
HEOGLLMH_02343 8.9e-17 K Transcriptional regulator
HEOGLLMH_02345 3.9e-68 yqaS L DNA packaging
HEOGLLMH_02346 9.7e-185 ps334 S Terminase-like family
HEOGLLMH_02347 6.5e-61 S Phage portal protein, SPP1 Gp6-like
HEOGLLMH_02348 2.6e-103 S Phage portal protein, SPP1 Gp6-like
HEOGLLMH_02349 1.3e-37 S Phage Mu protein F like protein
HEOGLLMH_02350 7.5e-58 S Domain of unknown function (DUF4355)
HEOGLLMH_02351 5.7e-145 S Phage capsid family
HEOGLLMH_02354 3e-26 S Phage gp6-like head-tail connector protein
HEOGLLMH_02355 4e-27 S Phage head-tail joining protein
HEOGLLMH_02357 7.7e-30 S Protein of unknown function (DUF3168)
HEOGLLMH_02358 8.2e-32 N domain, Protein
HEOGLLMH_02359 5.9e-08 chiA 3.2.1.14 GH18 G Belongs to the glycosyl hydrolase 18 family
HEOGLLMH_02360 3.3e-25 S Phage tail assembly chaperone protein, TAC
HEOGLLMH_02362 3.4e-127
HEOGLLMH_02363 1.3e-46
HEOGLLMH_02364 1.1e-225 S peptidoglycan catabolic process
HEOGLLMH_02370 1.8e-56 S Pfam:Phage_holin_4_1
HEOGLLMH_02371 2.8e-112 xlyB 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
HEOGLLMH_02372 3.7e-14 S SMI1-KNR4 cell-wall
HEOGLLMH_02373 4.7e-75 yobL S Bacterial EndoU nuclease
HEOGLLMH_02374 5.8e-75 yobL L Belongs to the WXG100 family
HEOGLLMH_02376 1.4e-81 T Histidine kinase-like ATPases
HEOGLLMH_02377 1.6e-19 S STAS-like domain of unknown function (DUF4325)
HEOGLLMH_02378 1.2e-15
HEOGLLMH_02379 5.1e-42 yjcN
HEOGLLMH_02380 2.3e-101 G Cupin
HEOGLLMH_02382 2e-219 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HEOGLLMH_02383 4.8e-146 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HEOGLLMH_02384 7.2e-121 ktrA P COG0569 K transport systems, NAD-binding component
HEOGLLMH_02385 2.1e-94 yuaB
HEOGLLMH_02386 2.7e-97 yuaC K Belongs to the GbsR family
HEOGLLMH_02387 5.5e-283 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
HEOGLLMH_02388 1.3e-44 gbsB 1.1.1.1 C alcohol dehydrogenase
HEOGLLMH_02389 5.3e-164 gbsB 1.1.1.1 C alcohol dehydrogenase
HEOGLLMH_02390 3.9e-107 yuaD S MOSC domain
HEOGLLMH_02391 3.3e-83 yuaE S DinB superfamily
HEOGLLMH_02392 1.9e-84 yuaF OU Membrane protein implicated in regulation of membrane protease activity
HEOGLLMH_02393 7.1e-118 yuaG 3.4.21.72 S protein conserved in bacteria
HEOGLLMH_02394 8.9e-51 yuaG 3.4.21.72 S protein conserved in bacteria
HEOGLLMH_02395 3.3e-98 thiT S Thiamine transporter protein (Thia_YuaJ)
HEOGLLMH_02397 3.4e-39 S COG NOG14552 non supervised orthologous group
HEOGLLMH_02402 1.6e-08
HEOGLLMH_02409 1.3e-09
HEOGLLMH_02410 7.8e-08
HEOGLLMH_02419 6.9e-78 tspO T membrane
HEOGLLMH_02420 2e-132 dksA T COG1734 DnaK suppressor protein
HEOGLLMH_02421 1.4e-21 menF 5.4.4.2 HQ Isochorismate synthase
HEOGLLMH_02422 2.6e-95 menF 5.4.4.2 HQ Isochorismate synthase
HEOGLLMH_02423 6.3e-72 menF 5.4.4.2 HQ Isochorismate synthase
HEOGLLMH_02424 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HEOGLLMH_02425 4.1e-51 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HEOGLLMH_02426 9.6e-58 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HEOGLLMH_02427 2.4e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HEOGLLMH_02428 1.2e-115 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HEOGLLMH_02429 1.3e-110 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HEOGLLMH_02430 4.6e-18 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HEOGLLMH_02431 6.5e-173 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HEOGLLMH_02432 2.3e-24 S Domain of Unknown Function (DUF1540)
HEOGLLMH_02433 5.4e-184 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HEOGLLMH_02434 1.2e-239 cydA 1.10.3.14 C oxidase, subunit
HEOGLLMH_02435 1.6e-41 rpmE2 J Ribosomal protein L31
HEOGLLMH_02436 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HEOGLLMH_02437 4.4e-38 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HEOGLLMH_02438 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HEOGLLMH_02439 6.1e-76 ytkA S YtkA-like
HEOGLLMH_02441 1.6e-76 dps P Belongs to the Dps family
HEOGLLMH_02442 4.6e-23 ytkC S Bacteriophage holin family
HEOGLLMH_02443 7.6e-29 ytkC S Bacteriophage holin family
HEOGLLMH_02444 9.8e-88 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
HEOGLLMH_02445 5.8e-141 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HEOGLLMH_02446 3.2e-144 ytlC P ABC transporter
HEOGLLMH_02447 9.6e-186 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HEOGLLMH_02448 5.7e-41 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HEOGLLMH_02449 5.8e-70 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HEOGLLMH_02450 1.6e-38 ytmB S Protein of unknown function (DUF2584)
HEOGLLMH_02451 1.3e-309 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HEOGLLMH_02452 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HEOGLLMH_02453 0.0 asnB 6.3.5.4 E Asparagine synthase
HEOGLLMH_02454 2.7e-130 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
HEOGLLMH_02455 6.9e-113 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
HEOGLLMH_02456 1.7e-22 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HEOGLLMH_02457 9.1e-18 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HEOGLLMH_02458 2.9e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
HEOGLLMH_02459 2.9e-212 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
HEOGLLMH_02461 8.7e-107 ytqB J Putative rRNA methylase
HEOGLLMH_02462 3.5e-24 yhcC S Fe-S oxidoreductase
HEOGLLMH_02463 8.4e-142 yhcC S Fe-S oxidoreductase
HEOGLLMH_02464 1.3e-39 ytzC S Protein of unknown function (DUF2524)
HEOGLLMH_02466 3.9e-66 ytrA K GntR family transcriptional regulator
HEOGLLMH_02467 1.9e-161 ytrB P abc transporter atp-binding protein
HEOGLLMH_02468 5e-171 S ABC-2 family transporter protein
HEOGLLMH_02469 8.8e-168 P ABC-2 family transporter protein
HEOGLLMH_02470 1.3e-125 ytrE V ABC transporter, ATP-binding protein
HEOGLLMH_02471 3.1e-221 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
HEOGLLMH_02472 8.2e-128 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEOGLLMH_02473 1.9e-178 T PhoQ Sensor
HEOGLLMH_02474 9.8e-135 bceA V ABC transporter, ATP-binding protein
HEOGLLMH_02475 0.0 bceB V ABC transporter (permease)
HEOGLLMH_02476 4.4e-109 ywaF S Integral membrane protein
HEOGLLMH_02477 2.3e-207 yttB EGP Major facilitator Superfamily
HEOGLLMH_02478 6.9e-139 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HEOGLLMH_02479 1.5e-49 ytvB S Protein of unknown function (DUF4257)
HEOGLLMH_02480 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HEOGLLMH_02481 5.6e-52 ytwF P Sulfurtransferase
HEOGLLMH_02482 3.5e-58 M Acetyltransferase (GNAT) domain
HEOGLLMH_02483 8.1e-251 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HEOGLLMH_02484 2.2e-168 amyD G Binding-protein-dependent transport system inner membrane component
HEOGLLMH_02485 1.8e-245 msmE G Bacterial extracellular solute-binding protein
HEOGLLMH_02486 5.7e-186 msmR K Transcriptional regulator
HEOGLLMH_02487 9e-26 yteV S Sporulation protein Cse60
HEOGLLMH_02488 4.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HEOGLLMH_02489 2e-209 ytfP S HI0933-like protein
HEOGLLMH_02490 1.7e-293 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEOGLLMH_02491 2.2e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HEOGLLMH_02492 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
HEOGLLMH_02493 4.9e-128 ythP V ABC transporter
HEOGLLMH_02494 1.1e-217 ythQ U Bacterial ABC transporter protein EcsB
HEOGLLMH_02495 2e-171 pbuO S permease
HEOGLLMH_02496 5.6e-180 pepV 3.5.1.18 E Dipeptidase
HEOGLLMH_02497 3.5e-70 pepV 3.5.1.18 E Dipeptidase
HEOGLLMH_02498 1.1e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HEOGLLMH_02499 8e-102 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HEOGLLMH_02500 3.7e-168 ytlQ
HEOGLLMH_02501 4.7e-179 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HEOGLLMH_02502 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
HEOGLLMH_02503 3.5e-45 ytzH S YtzH-like protein
HEOGLLMH_02504 3.2e-164 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
HEOGLLMH_02505 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
HEOGLLMH_02506 1.7e-51 ytzB S small secreted protein
HEOGLLMH_02507 5.8e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HEOGLLMH_02508 5e-78 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
HEOGLLMH_02509 1.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HEOGLLMH_02510 3.7e-148 ytpQ S Belongs to the UPF0354 family
HEOGLLMH_02511 3.1e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HEOGLLMH_02512 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HEOGLLMH_02513 2.4e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HEOGLLMH_02514 1.7e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HEOGLLMH_02516 2.9e-43 ytxJ O Protein of unknown function (DUF2847)
HEOGLLMH_02517 1.9e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HEOGLLMH_02518 9.4e-161 ccpA K catabolite control protein A
HEOGLLMH_02519 5.1e-145 motA N flagellar motor
HEOGLLMH_02520 3.7e-120 motS N Flagellar motor protein
HEOGLLMH_02521 2.3e-231 acuC BQ histone deacetylase
HEOGLLMH_02522 2.5e-118 acuB S Domain in cystathionine beta-synthase and other proteins.
HEOGLLMH_02523 1.2e-120 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HEOGLLMH_02524 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HEOGLLMH_02525 2.1e-163 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HEOGLLMH_02526 6e-58 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HEOGLLMH_02527 8.7e-48 azlD S Branched-chain amino acid transport protein (AzlD)
HEOGLLMH_02528 5.2e-125 azlC E AzlC protein
HEOGLLMH_02529 4.9e-148 K Transcriptional regulator
HEOGLLMH_02530 3.7e-62 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEOGLLMH_02531 1.2e-74 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEOGLLMH_02533 1e-139 E GDSL-like Lipase/Acylhydrolase family
HEOGLLMH_02535 2e-91 yhbO 1.11.1.6, 3.5.1.124 S protease
HEOGLLMH_02536 2.5e-09
HEOGLLMH_02537 3.4e-222 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HEOGLLMH_02538 1.8e-33 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HEOGLLMH_02539 5.2e-30
HEOGLLMH_02540 1.4e-28 S Phage-like element PBSX protein XtrA
HEOGLLMH_02542 4e-87 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HEOGLLMH_02544 1.3e-102
HEOGLLMH_02546 8.6e-20 yokH G SMI1 / KNR4 family
HEOGLLMH_02547 1.6e-57 yokH G SMI1 / KNR4 family
HEOGLLMH_02548 7.2e-261 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HEOGLLMH_02549 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HEOGLLMH_02550 7.5e-233 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
HEOGLLMH_02551 1.1e-86 ytsP 1.8.4.14 T GAF domain-containing protein
HEOGLLMH_02552 7e-136 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HEOGLLMH_02553 2.3e-234 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HEOGLLMH_02554 3.1e-240 braB E Component of the transport system for branched-chain amino acids
HEOGLLMH_02555 1.2e-208 iscS2 2.8.1.7 E Cysteine desulfurase
HEOGLLMH_02556 3.9e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HEOGLLMH_02557 3.9e-31 sspB S spore protein
HEOGLLMH_02558 1.6e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HEOGLLMH_02559 0.0 ytcJ S amidohydrolase
HEOGLLMH_02560 3.3e-152 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HEOGLLMH_02561 8.4e-182 sppA OU signal peptide peptidase SppA
HEOGLLMH_02562 5.9e-88 yteJ S RDD family
HEOGLLMH_02563 4.1e-20 ytfI S Protein of unknown function (DUF2953)
HEOGLLMH_02564 5e-66 ytfI S Protein of unknown function (DUF2953)
HEOGLLMH_02565 1.7e-56 ytfJ S Sporulation protein YtfJ
HEOGLLMH_02566 1.1e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HEOGLLMH_02567 2.8e-182 ytxK 2.1.1.72 L DNA methylase
HEOGLLMH_02568 4.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HEOGLLMH_02569 6.8e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HEOGLLMH_02570 1.9e-98 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HEOGLLMH_02571 4.8e-125 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HEOGLLMH_02572 1.9e-66 argH 4.3.2.1 E argininosuccinate lyase
HEOGLLMH_02573 1e-156 argH 4.3.2.1 E argininosuccinate lyase
HEOGLLMH_02575 1.7e-79 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEOGLLMH_02576 2.3e-44 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEOGLLMH_02577 4.3e-129 ytkL S Belongs to the UPF0173 family
HEOGLLMH_02578 7.7e-95 ytoI K transcriptional regulator containing CBS domains
HEOGLLMH_02579 1.6e-132 ytoI K transcriptional regulator containing CBS domains
HEOGLLMH_02580 1.5e-46 ytpI S YtpI-like protein
HEOGLLMH_02581 7.8e-27 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
HEOGLLMH_02582 3.7e-122 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
HEOGLLMH_02583 4.4e-23
HEOGLLMH_02584 5.1e-87 ytrI
HEOGLLMH_02585 3.2e-56 ytrH S Sporulation protein YtrH
HEOGLLMH_02586 0.0 dnaE 2.7.7.7 L DNA polymerase
HEOGLLMH_02587 1.8e-212 dnaE 2.7.7.7 L DNA polymerase
HEOGLLMH_02588 1.3e-224 ytsJ 1.1.1.38 C Malate dehydrogenase
HEOGLLMH_02589 2.6e-152 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HEOGLLMH_02590 1.1e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HEOGLLMH_02591 6.8e-181 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HEOGLLMH_02592 1.8e-78 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HEOGLLMH_02593 1.1e-166 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HEOGLLMH_02594 2.1e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
HEOGLLMH_02595 2.4e-193 ytvI S sporulation integral membrane protein YtvI
HEOGLLMH_02596 1.1e-72 yeaL S membrane
HEOGLLMH_02597 8e-47 yjdF S Protein of unknown function (DUF2992)
HEOGLLMH_02598 2.8e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
HEOGLLMH_02599 3.9e-240 icd 1.1.1.42 C isocitrate
HEOGLLMH_02600 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
HEOGLLMH_02601 3.1e-128 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEOGLLMH_02602 7.5e-308 phoR 2.7.13.3 T Signal transduction histidine kinase
HEOGLLMH_02603 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HEOGLLMH_02604 8e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HEOGLLMH_02605 9.5e-107 ytaF P Probably functions as a manganese efflux pump
HEOGLLMH_02606 1.2e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HEOGLLMH_02607 7.6e-160 ytbE S reductase
HEOGLLMH_02608 1.3e-205 ytbD EGP Major facilitator Superfamily
HEOGLLMH_02609 2e-67 ytcD K Transcriptional regulator
HEOGLLMH_02610 3e-195 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HEOGLLMH_02611 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HEOGLLMH_02612 1.1e-40 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HEOGLLMH_02613 4.7e-23 dnaB L Membrane attachment protein
HEOGLLMH_02614 6.9e-215 dnaB L Membrane attachment protein
HEOGLLMH_02615 4.3e-172 dnaI L Primosomal protein DnaI
HEOGLLMH_02616 6e-109 ytxB S SNARE associated Golgi protein
HEOGLLMH_02617 3e-153 ytxC S YtxC-like family
HEOGLLMH_02618 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HEOGLLMH_02619 7.1e-152 ysaA S HAD-hyrolase-like
HEOGLLMH_02620 0.0 lytS 2.7.13.3 T Histidine kinase
HEOGLLMH_02621 3.8e-131 lytT T COG3279 Response regulator of the LytR AlgR family
HEOGLLMH_02622 9.4e-24 lrgA S effector of murein hydrolase LrgA
HEOGLLMH_02623 3.8e-109 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HEOGLLMH_02624 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HEOGLLMH_02625 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HEOGLLMH_02626 2.7e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HEOGLLMH_02627 7e-43 ysdA S Membrane
HEOGLLMH_02628 1.7e-66 ysdB S Sigma-w pathway protein YsdB
HEOGLLMH_02629 1.4e-206 ysdC G COG1363 Cellulase M and related proteins
HEOGLLMH_02630 1.8e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HEOGLLMH_02631 2.8e-298 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HEOGLLMH_02632 4.2e-217 araB 2.7.1.16 C Belongs to the ribulokinase family
HEOGLLMH_02633 1.5e-86 araB 2.7.1.16 C Belongs to the ribulokinase family
HEOGLLMH_02634 9.3e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HEOGLLMH_02635 3.4e-112 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HEOGLLMH_02636 6.5e-226 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HEOGLLMH_02637 1.5e-252 araN G carbohydrate transport
HEOGLLMH_02638 4.9e-168 araP P PFAM binding-protein-dependent transport systems inner membrane component
HEOGLLMH_02639 3.6e-29 araQ G transport system permease
HEOGLLMH_02640 5.8e-92 araQ G transport system permease
HEOGLLMH_02641 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
HEOGLLMH_02642 0.0 cstA T Carbon starvation protein
HEOGLLMH_02643 1.4e-253 glcF C Glycolate oxidase
HEOGLLMH_02644 8.2e-260 glcD 1.1.3.15 C FAD binding domain
HEOGLLMH_02645 2.6e-205 ysfB KT regulator
HEOGLLMH_02646 5.5e-24 sspI S Belongs to the SspI family
HEOGLLMH_02647 3.2e-98 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEOGLLMH_02648 5.1e-126 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HEOGLLMH_02649 3.8e-43 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HEOGLLMH_02650 1.8e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HEOGLLMH_02651 2.5e-105 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HEOGLLMH_02652 5.6e-141 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HEOGLLMH_02653 9.3e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEOGLLMH_02654 9.1e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HEOGLLMH_02655 4.7e-83 cvpA S membrane protein, required for colicin V production
HEOGLLMH_02656 0.0 polX L COG1796 DNA polymerase IV (family X)
HEOGLLMH_02657 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HEOGLLMH_02658 4.7e-67 yshE S membrane
HEOGLLMH_02659 1.8e-124 ywbB S Protein of unknown function (DUF2711)
HEOGLLMH_02660 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HEOGLLMH_02661 2.5e-25 fadR K Transcriptional regulator
HEOGLLMH_02662 9.4e-68 fadR K Transcriptional regulator
HEOGLLMH_02663 5.4e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HEOGLLMH_02664 5.9e-138 etfB C Electron transfer flavoprotein
HEOGLLMH_02665 1.2e-177 etfA C Electron transfer flavoprotein
HEOGLLMH_02666 4.3e-299 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HEOGLLMH_02667 2.5e-52 trxA O Belongs to the thioredoxin family
HEOGLLMH_02668 4.2e-60 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HEOGLLMH_02669 1.8e-67 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HEOGLLMH_02670 1.7e-137 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HEOGLLMH_02671 7e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HEOGLLMH_02672 7.9e-35 yslB S Protein of unknown function (DUF2507)
HEOGLLMH_02673 1.3e-31 yslB S Protein of unknown function (DUF2507)
HEOGLLMH_02674 4.8e-108 sdhC C succinate dehydrogenase
HEOGLLMH_02675 7.9e-76 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HEOGLLMH_02676 3.4e-199 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HEOGLLMH_02677 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HEOGLLMH_02678 2.4e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
HEOGLLMH_02679 5.2e-11 gerE K response regulator
HEOGLLMH_02680 1.7e-47 yqaB E IrrE N-terminal-like domain
HEOGLLMH_02681 3e-17
HEOGLLMH_02682 2.8e-35 K sequence-specific DNA binding
HEOGLLMH_02683 3.6e-19 K Helix-turn-helix XRE-family like proteins
HEOGLLMH_02685 5e-32 K Phage regulatory protein Rha (Phage_pRha)
HEOGLLMH_02686 4.9e-86
HEOGLLMH_02689 9.2e-22 J translation initiation factor activity
HEOGLLMH_02691 9.1e-154 yqaJ L YqaJ-like viral recombinase domain
HEOGLLMH_02692 2.1e-125 recT L RecT family
HEOGLLMH_02693 6.7e-43 3.1.3.16 L DnaD domain protein
HEOGLLMH_02694 3.8e-57 L Bacterial dnaA protein
HEOGLLMH_02699 1.4e-47 S Protein of unknown function (DUF1064)
HEOGLLMH_02701 5e-17 yqaO S Phage-like element PBSX protein XtrA
HEOGLLMH_02703 1e-15
HEOGLLMH_02705 5.2e-88
HEOGLLMH_02706 2.6e-10
HEOGLLMH_02708 3.6e-58
HEOGLLMH_02716 1.3e-46
HEOGLLMH_02720 6.8e-46 L Transposase
HEOGLLMH_02723 1.5e-23 yqaS L DNA packaging
HEOGLLMH_02724 9.2e-35 yqaS
HEOGLLMH_02725 2.4e-183 ps334 S Terminase-like family
HEOGLLMH_02726 7.7e-157 S Phage portal protein, SPP1 Gp6-like
HEOGLLMH_02727 6.9e-17
HEOGLLMH_02728 1.8e-38 S Protein of unknown function (DUF2829)
HEOGLLMH_02729 1.8e-48 S Domain of unknown function (DUF4355)
HEOGLLMH_02730 7.1e-121 S P22 coat protein - gene protein 5
HEOGLLMH_02732 2.7e-35 S Phage Mu protein F like protein
HEOGLLMH_02733 2.2e-17 S Phage gp6-like head-tail connector protein
HEOGLLMH_02734 1e-47
HEOGLLMH_02735 5.1e-26
HEOGLLMH_02736 3.7e-31
HEOGLLMH_02737 1.3e-86 Z012_02110 S Protein of unknown function (DUF3383)
HEOGLLMH_02738 1.4e-34
HEOGLLMH_02739 2.4e-15
HEOGLLMH_02740 4.1e-54 D Phage tail tape measure protein, TP901 family
HEOGLLMH_02741 2.5e-22 N phage tail tape measure protein
HEOGLLMH_02742 7.4e-107 D Phage tail tape measure protein
HEOGLLMH_02743 2.1e-24 3.5.1.28 M LysM domain
HEOGLLMH_02744 7e-30
HEOGLLMH_02745 2.3e-88
HEOGLLMH_02746 7.7e-26
HEOGLLMH_02747 3e-25 S Protein of unknown function (DUF2634)
HEOGLLMH_02748 2.9e-101 Z012_12235 S homolog of phage Mu protein gp47
HEOGLLMH_02749 3.3e-46
HEOGLLMH_02750 6.1e-49
HEOGLLMH_02752 1.6e-17 xkdX
HEOGLLMH_02753 1.5e-27 xhlA S Haemolysin XhlA
HEOGLLMH_02754 6.7e-30 xhlB S SPP1 phage holin
HEOGLLMH_02755 4.8e-72 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HEOGLLMH_02757 6.3e-14 K Helix-turn-helix domain
HEOGLLMH_02758 1.5e-29 S SMI1 / KNR4 family
HEOGLLMH_02759 2e-73 yobL S Bacterial EndoU nuclease
HEOGLLMH_02760 7.6e-108 yobL L Belongs to the WXG100 family
HEOGLLMH_02761 1.7e-18
HEOGLLMH_02763 5e-183 S Aspartate phosphatase response regulator
HEOGLLMH_02765 1.1e-15
HEOGLLMH_02766 3.6e-08
HEOGLLMH_02767 1.4e-09 lexA 3.4.21.88 KT domain protein
HEOGLLMH_02768 5.1e-159 L Recombinase
HEOGLLMH_02769 9.3e-37 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
HEOGLLMH_02770 6.1e-25 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
HEOGLLMH_02771 2.7e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HEOGLLMH_02772 8.1e-199 gerM S COG5401 Spore germination protein
HEOGLLMH_02773 9.9e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HEOGLLMH_02774 1.1e-101 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HEOGLLMH_02775 9.1e-92 ysnB S Phosphoesterase
HEOGLLMH_02780 3.6e-17 ilvB 2.2.1.6 E Acetolactate synthase
HEOGLLMH_02781 3.7e-186 ilvB 2.2.1.6 E Acetolactate synthase
HEOGLLMH_02782 5.5e-56 ilvB 2.2.1.6 E Acetolactate synthase
HEOGLLMH_02783 2.1e-83 ilvN 2.2.1.6 E Acetolactate synthase
HEOGLLMH_02784 6.7e-143 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HEOGLLMH_02785 5.8e-192 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HEOGLLMH_02786 4.8e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HEOGLLMH_02787 1.4e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HEOGLLMH_02788 6.2e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HEOGLLMH_02789 2.4e-189 ysoA H Tetratricopeptide repeat
HEOGLLMH_02790 1.1e-213 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HEOGLLMH_02791 3.8e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HEOGLLMH_02792 7.2e-92 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
HEOGLLMH_02793 1.2e-208 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
HEOGLLMH_02794 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HEOGLLMH_02795 8.8e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
HEOGLLMH_02796 2.2e-66 ysxD
HEOGLLMH_02797 3.1e-248 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HEOGLLMH_02798 8e-146 hemX O cytochrome C
HEOGLLMH_02799 5.1e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HEOGLLMH_02800 4.3e-141 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HEOGLLMH_02801 1.7e-184 hemB 4.2.1.24 H Belongs to the ALAD family
HEOGLLMH_02802 1.9e-187 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HEOGLLMH_02803 3.2e-33 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HEOGLLMH_02804 9.9e-216 spoVID M stage VI sporulation protein D
HEOGLLMH_02805 4.7e-193 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HEOGLLMH_02806 2.1e-25
HEOGLLMH_02807 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HEOGLLMH_02808 8.1e-238 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HEOGLLMH_02809 8.8e-106 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HEOGLLMH_02810 1.3e-139 spoIIB S Sporulation related domain
HEOGLLMH_02811 1.6e-100 maf D septum formation protein Maf
HEOGLLMH_02812 1.4e-69 radC E Belongs to the UPF0758 family
HEOGLLMH_02813 1.3e-265 S Recombinase
HEOGLLMH_02814 2.4e-80 S Pfam:Peptidase_M78
HEOGLLMH_02815 1.5e-66 S sequence-specific DNA binding
HEOGLLMH_02816 5.7e-08 plcR K helix-turn-helix
HEOGLLMH_02819 8.7e-20 S Uncharacterized protein YqaH
HEOGLLMH_02821 6.2e-69 S Phage regulatory protein Rha (Phage_pRha)
HEOGLLMH_02824 3e-49 L DnaD domain protein
HEOGLLMH_02825 6.7e-25 S Loader and inhibitor of phage G40P
HEOGLLMH_02826 8.8e-171 dnaB 3.6.4.12 L replicative DNA helicase
HEOGLLMH_02827 3.1e-25
HEOGLLMH_02830 1.7e-25 S Phage-like element PBSX protein XtrA
HEOGLLMH_02831 6.8e-79 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HEOGLLMH_02832 3.1e-30 S HicB_like antitoxin of bacterial toxin-antitoxin system
HEOGLLMH_02833 6.4e-19 N PFAM YcfA family protein
HEOGLLMH_02834 1e-44
HEOGLLMH_02838 1.4e-68 S HNH endonuclease
HEOGLLMH_02839 2.2e-22
HEOGLLMH_02840 3.9e-87 S Phage terminase, small subunit
HEOGLLMH_02841 5.1e-44 S Terminase
HEOGLLMH_02842 3.9e-146 S Terminase
HEOGLLMH_02843 2.3e-10
HEOGLLMH_02844 1.3e-240 S Phage portal protein
HEOGLLMH_02845 9.1e-110 S peptidase activity
HEOGLLMH_02846 3.4e-182 S capsid protein
HEOGLLMH_02848 7e-14 S peptidoglycan catabolic process
HEOGLLMH_02850 2.7e-22 S peptidoglycan catabolic process
HEOGLLMH_02851 8.6e-16 S Phage gp6-like head-tail connector protein
HEOGLLMH_02852 1.4e-25 S Phage head-tail joining protein
HEOGLLMH_02853 1.8e-47 S Bacteriophage HK97-gp10, putative tail-component
HEOGLLMH_02854 1.5e-30
HEOGLLMH_02855 7.6e-61
HEOGLLMH_02856 2.7e-23
HEOGLLMH_02857 5.7e-11
HEOGLLMH_02858 0.0 S peptidoglycan catabolic process
HEOGLLMH_02859 6.5e-55 S peptidoglycan catabolic process
HEOGLLMH_02860 3.2e-110 S Phage tail protein
HEOGLLMH_02861 9.8e-173 NU Prophage endopeptidase tail
HEOGLLMH_02862 6.2e-42 NU Prophage endopeptidase tail
HEOGLLMH_02863 2.7e-288 S Peptidase_G2, IMC autoproteolytic cleavage domain
HEOGLLMH_02864 8.2e-123 S Peptidase_G2, IMC autoproteolytic cleavage domain
HEOGLLMH_02865 6.8e-102 S Domain of unknown function (DUF2479)
HEOGLLMH_02866 1.6e-13 S Domain of unknown function (DUF2479)
HEOGLLMH_02869 2.4e-58 S Pfam:Phage_holin_4_1
HEOGLLMH_02870 7.5e-132 xlyB 3.5.1.28 CBM50 MT N-acetylmuramoyl-L-alanine amidase
HEOGLLMH_02874 1.1e-24 S aspartate phosphatase
HEOGLLMH_02876 1.4e-64 S aspartate phosphatase
HEOGLLMH_02877 4e-184 mreB D Rod shape-determining protein MreB
HEOGLLMH_02878 1.2e-157 mreC M Involved in formation and maintenance of cell shape
HEOGLLMH_02879 1.4e-84 mreD M shape-determining protein
HEOGLLMH_02880 1.5e-97 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HEOGLLMH_02881 8e-143 minD D Belongs to the ParA family
HEOGLLMH_02882 6.5e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
HEOGLLMH_02883 3.3e-96 spoIVFB S Stage IV sporulation protein
HEOGLLMH_02884 1e-37 spoIVFB S Stage IV sporulation protein
HEOGLLMH_02885 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
HEOGLLMH_02886 8e-48 ysxB J ribosomal protein
HEOGLLMH_02887 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HEOGLLMH_02888 8.7e-107 spo0B T Sporulation initiation phospho-transferase B, C-terminal
HEOGLLMH_02889 7.6e-236 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HEOGLLMH_02890 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
HEOGLLMH_02891 1.2e-160 pheA 4.2.1.51 E Prephenate dehydratase
HEOGLLMH_02892 1.1e-95 niaR S small molecule binding protein (contains 3H domain)
HEOGLLMH_02893 2.7e-224 nifS 2.8.1.7 E Cysteine desulfurase
HEOGLLMH_02894 2.5e-302 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HEOGLLMH_02895 2.1e-213 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HEOGLLMH_02896 7.9e-147 safA M spore coat assembly protein SafA
HEOGLLMH_02897 1.1e-45 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HEOGLLMH_02899 1.4e-92 bofC S BofC C-terminal domain
HEOGLLMH_02900 3.3e-22 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HEOGLLMH_02901 3.1e-72 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HEOGLLMH_02902 2.4e-78 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HEOGLLMH_02903 2.3e-90 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HEOGLLMH_02904 1.6e-20 yrzS S Protein of unknown function (DUF2905)
HEOGLLMH_02905 8.4e-51 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HEOGLLMH_02906 7.1e-133 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HEOGLLMH_02907 8.8e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HEOGLLMH_02908 5.6e-37 yajC U Preprotein translocase subunit YajC
HEOGLLMH_02909 2.4e-60 yrzE S Protein of unknown function (DUF3792)
HEOGLLMH_02910 2.3e-88 yrbG S membrane
HEOGLLMH_02911 1.2e-228 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEOGLLMH_02912 5e-32 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEOGLLMH_02913 1.3e-50 yrzD S Post-transcriptional regulator
HEOGLLMH_02914 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HEOGLLMH_02915 7.3e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
HEOGLLMH_02916 5.7e-47 yrvD S Lipopolysaccharide assembly protein A domain
HEOGLLMH_02917 1.1e-10 recJ L DHH family
HEOGLLMH_02918 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HEOGLLMH_02919 2.9e-90 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HEOGLLMH_02920 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HEOGLLMH_02921 5.1e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HEOGLLMH_02922 4.1e-276 lytH 3.5.1.28 M COG3103 SH3 domain protein
HEOGLLMH_02925 8.8e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
HEOGLLMH_02926 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HEOGLLMH_02927 9.6e-138 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HEOGLLMH_02928 1.2e-219 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HEOGLLMH_02929 2.1e-32 cymR K Transcriptional regulator
HEOGLLMH_02930 3e-212 iscS 2.8.1.7 E Cysteine desulfurase
HEOGLLMH_02931 2.4e-222 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HEOGLLMH_02932 1.7e-18 S COG0457 FOG TPR repeat
HEOGLLMH_02933 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HEOGLLMH_02934 1.8e-83 yrrD S protein conserved in bacteria
HEOGLLMH_02935 2.9e-30 yrzR
HEOGLLMH_02936 2.1e-08 S Protein of unknown function (DUF3918)
HEOGLLMH_02937 1.3e-106 glnP P ABC transporter
HEOGLLMH_02938 1.2e-109 gluC P ABC transporter
HEOGLLMH_02939 2.2e-134 glnH ET Belongs to the bacterial solute-binding protein 3 family
HEOGLLMH_02940 5.4e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HEOGLLMH_02941 7.3e-22 yrrI S AI-2E family transporter
HEOGLLMH_02942 2e-133 yrrI S AI-2E family transporter
HEOGLLMH_02943 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HEOGLLMH_02944 1.7e-41 yrzL S Belongs to the UPF0297 family
HEOGLLMH_02945 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HEOGLLMH_02946 7.1e-46 yrzB S Belongs to the UPF0473 family
HEOGLLMH_02947 2.3e-43 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HEOGLLMH_02948 3.5e-36 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HEOGLLMH_02949 8.4e-66 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HEOGLLMH_02950 9.5e-118 yrrM 2.1.1.104 S O-methyltransferase
HEOGLLMH_02951 1.7e-173 yegQ O Peptidase U32
HEOGLLMH_02952 9.3e-34 yegQ O COG0826 Collagenase and related proteases
HEOGLLMH_02953 2.6e-199 yegQ O COG0826 Collagenase and related proteases
HEOGLLMH_02954 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
HEOGLLMH_02955 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HEOGLLMH_02956 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
HEOGLLMH_02957 8.8e-10 yrrS S Protein of unknown function (DUF1510)
HEOGLLMH_02958 4.9e-30 yrrS S Protein of unknown function (DUF1510)
HEOGLLMH_02959 4.1e-27 yrzA S Protein of unknown function (DUF2536)
HEOGLLMH_02960 7.9e-117 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
HEOGLLMH_02961 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HEOGLLMH_02962 4.7e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
HEOGLLMH_02963 9.8e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HEOGLLMH_02964 3e-34 yrhC S YrhC-like protein
HEOGLLMH_02965 4.5e-80 yrhD S Protein of unknown function (DUF1641)
HEOGLLMH_02966 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
HEOGLLMH_02967 6e-61 yrhF S Uncharacterized conserved protein (DUF2294)
HEOGLLMH_02968 3.6e-126 focA P Formate nitrite
HEOGLLMH_02970 3.9e-93 yrhH Q methyltransferase
HEOGLLMH_02971 9.1e-101 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
HEOGLLMH_02972 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HEOGLLMH_02973 9.3e-170 ynfM EGP Major facilitator Superfamily
HEOGLLMH_02974 2.9e-32 ynfM EGP Major facilitator Superfamily
HEOGLLMH_02975 1.1e-164 yybE K Transcriptional regulator
HEOGLLMH_02976 6.8e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HEOGLLMH_02977 4.7e-182 romA S Beta-lactamase superfamily domain
HEOGLLMH_02978 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
HEOGLLMH_02979 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
HEOGLLMH_02980 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
HEOGLLMH_02981 4.5e-129 glvR K Helix-turn-helix domain, rpiR family
HEOGLLMH_02982 1e-50 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
HEOGLLMH_02983 1.2e-70 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
HEOGLLMH_02984 1.4e-48 S hydrolase
HEOGLLMH_02985 1.9e-74 S hydrolase
HEOGLLMH_02987 8.9e-92 yrdA S DinB family
HEOGLLMH_02988 1.4e-19 yyaR K acetyltransferase
HEOGLLMH_02989 4.6e-167 tetL EGP Major facilitator Superfamily
HEOGLLMH_02990 2.6e-39 tetL EGP Major facilitator Superfamily
HEOGLLMH_02991 3.6e-90 adk 2.7.4.3 F adenylate kinase activity
HEOGLLMH_02992 4.7e-20 leuB1 1.1.1.85 CE Isocitrate/isopropylmalate dehydrogenase
HEOGLLMH_02993 4.9e-42 ydeE K AraC family transcriptional regulator
HEOGLLMH_02994 2.8e-63 ydeE K AraC family transcriptional regulator
HEOGLLMH_02995 7.2e-92 K Transcriptional regulator PadR-like family
HEOGLLMH_02996 7.3e-13 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
HEOGLLMH_02997 2.8e-128 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
HEOGLLMH_02998 1.2e-86 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEOGLLMH_02999 2e-217 EGP Major facilitator Superfamily
HEOGLLMH_03000 1.5e-10 2.3.1.57 K Acetyltransferase (GNAT) domain
HEOGLLMH_03001 2.3e-12 2.3.1.57 K Acetyltransferase (GNAT) domain
HEOGLLMH_03002 4.2e-107 yqeD S SNARE associated Golgi protein
HEOGLLMH_03003 4.9e-139 3.5.1.104 G Polysaccharide deacetylase
HEOGLLMH_03004 1.3e-139 yqeF E GDSL-like Lipase/Acylhydrolase
HEOGLLMH_03006 2e-94 yqeG S hydrolase of the HAD superfamily
HEOGLLMH_03007 1.5e-213 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HEOGLLMH_03008 7.8e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HEOGLLMH_03009 1.8e-44 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
HEOGLLMH_03010 1.9e-106 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HEOGLLMH_03011 3.3e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HEOGLLMH_03012 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HEOGLLMH_03013 1.6e-137 yqeM Q Methyltransferase
HEOGLLMH_03014 6.5e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEOGLLMH_03015 6.2e-103 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
HEOGLLMH_03016 6.2e-97 comEB 3.5.4.12 F ComE operon protein 2
HEOGLLMH_03017 1.4e-276 comEC S Competence protein ComEC
HEOGLLMH_03018 4.4e-143 comEC S Competence protein ComEC
HEOGLLMH_03019 2.9e-38 holA 2.7.7.7 L DNA polymerase III delta subunit
HEOGLLMH_03020 4.3e-31 holA 2.7.7.7 L DNA polymerase III delta subunit
HEOGLLMH_03021 4.9e-39 holA 2.7.7.7 L DNA polymerase III delta subunit
HEOGLLMH_03022 1.5e-26 rpsT J Binds directly to 16S ribosomal RNA
HEOGLLMH_03023 5e-16 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HEOGLLMH_03024 7e-107 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HEOGLLMH_03025 3.6e-177 spoIIP M stage II sporulation protein P
HEOGLLMH_03026 3.8e-54 yqxA S Protein of unknown function (DUF3679)
HEOGLLMH_03027 1.3e-282 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HEOGLLMH_03028 2.2e-48 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HEOGLLMH_03029 1.8e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
HEOGLLMH_03030 2.3e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HEOGLLMH_03031 3.5e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HEOGLLMH_03032 8.5e-117 dnaK O Heat shock 70 kDa protein
HEOGLLMH_03033 1.2e-41 dnaK O Heat shock 70 kDa protein
HEOGLLMH_03034 6.1e-80 dnaK O Heat shock 70 kDa protein
HEOGLLMH_03035 1.7e-13 dnaK O Heat shock 70 kDa protein
HEOGLLMH_03036 1.1e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HEOGLLMH_03037 1.6e-174 prmA J Methylates ribosomal protein L11
HEOGLLMH_03038 1.5e-138 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HEOGLLMH_03039 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
HEOGLLMH_03040 1e-157 yqeW P COG1283 Na phosphate symporter
HEOGLLMH_03041 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HEOGLLMH_03042 1.2e-68 yqeY S Yqey-like protein
HEOGLLMH_03043 1.7e-230 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
HEOGLLMH_03044 1.6e-121 yqfA S UPF0365 protein
HEOGLLMH_03045 2.3e-51 yqfB
HEOGLLMH_03046 9.3e-46 yqfC S sporulation protein YqfC
HEOGLLMH_03047 3.3e-15 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
HEOGLLMH_03048 3.4e-67 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
HEOGLLMH_03049 4.5e-103 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
HEOGLLMH_03050 3.8e-176 phoH T Phosphate starvation-inducible protein PhoH
HEOGLLMH_03051 0.0 yqfF S membrane-associated HD superfamily hydrolase
HEOGLLMH_03052 4.3e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HEOGLLMH_03053 1.3e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HEOGLLMH_03054 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HEOGLLMH_03055 5.9e-103 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HEOGLLMH_03056 2.8e-48 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HEOGLLMH_03057 1.8e-16 S YqzL-like protein
HEOGLLMH_03058 1.2e-143 recO L Involved in DNA repair and RecF pathway recombination
HEOGLLMH_03059 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HEOGLLMH_03060 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HEOGLLMH_03061 4.5e-112 ccpN K CBS domain
HEOGLLMH_03062 2e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HEOGLLMH_03063 6.1e-88 yaiI S Belongs to the UPF0178 family
HEOGLLMH_03064 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HEOGLLMH_03065 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HEOGLLMH_03066 1.1e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
HEOGLLMH_03067 3.8e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
HEOGLLMH_03068 5.6e-211 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HEOGLLMH_03069 1.7e-176 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HEOGLLMH_03070 6.2e-51 yqfQ S YqfQ-like protein
HEOGLLMH_03071 7.5e-228 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HEOGLLMH_03072 2e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HEOGLLMH_03073 9.3e-37 yqfT S Protein of unknown function (DUF2624)
HEOGLLMH_03074 1.4e-156 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HEOGLLMH_03075 2.9e-72 zur P Belongs to the Fur family
HEOGLLMH_03076 4.2e-109 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
HEOGLLMH_03077 2.3e-52 yqfX S membrane
HEOGLLMH_03078 7e-188 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HEOGLLMH_03079 1.4e-47 yqfZ M LysM domain
HEOGLLMH_03080 3.3e-130 yqgB S Protein of unknown function (DUF1189)
HEOGLLMH_03081 3.8e-71 yqgC S protein conserved in bacteria
HEOGLLMH_03082 4.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
HEOGLLMH_03083 2e-228 yqgE EGP Major facilitator superfamily
HEOGLLMH_03084 0.0 pbpA 3.4.16.4 M penicillin-binding protein
HEOGLLMH_03085 3.4e-54 pstS P Phosphate
HEOGLLMH_03086 1.9e-71 pstS P Phosphate
HEOGLLMH_03087 1.4e-159 pstC P probably responsible for the translocation of the substrate across the membrane
HEOGLLMH_03088 1.2e-155 pstA P Phosphate transport system permease
HEOGLLMH_03089 5.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HEOGLLMH_03090 3.6e-67 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HEOGLLMH_03091 1.2e-58 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HEOGLLMH_03092 3.7e-76 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HEOGLLMH_03093 1.2e-50 yqzD
HEOGLLMH_03094 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HEOGLLMH_03095 8.1e-94 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HEOGLLMH_03096 4e-07 yqgO
HEOGLLMH_03097 2.9e-233 nhaC C Na H antiporter
HEOGLLMH_03098 1e-28 yqgQ S Protein conserved in bacteria
HEOGLLMH_03099 7.5e-180 glcK 2.7.1.2 G Glucokinase
HEOGLLMH_03100 9.6e-144 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
HEOGLLMH_03101 4.5e-60 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
HEOGLLMH_03102 1.7e-114 yqgU
HEOGLLMH_03103 2.4e-65 yqgU
HEOGLLMH_03104 6.9e-50 yqgV S Thiamine-binding protein
HEOGLLMH_03105 5.4e-20 yqgW S Protein of unknown function (DUF2759)
HEOGLLMH_03106 8.1e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HEOGLLMH_03107 3.1e-37 yqgY S Protein of unknown function (DUF2626)
HEOGLLMH_03108 9.2e-65 yqgZ 1.20.4.1 P Belongs to the ArsC family
HEOGLLMH_03110 7e-150 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HEOGLLMH_03111 1.4e-113 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HEOGLLMH_03112 1.9e-99 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HEOGLLMH_03113 4.1e-186 corA P Mg2 transporter protein
HEOGLLMH_03114 3.4e-62 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HEOGLLMH_03115 4e-127 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HEOGLLMH_03116 5.3e-96 comGB NU COG1459 Type II secretory pathway, component PulF
HEOGLLMH_03117 9.1e-75 comGB NU COG1459 Type II secretory pathway, component PulF
HEOGLLMH_03118 8.9e-50 comGC U Required for transformation and DNA binding
HEOGLLMH_03119 1.6e-73 gspH NU Tfp pilus assembly protein FimT
HEOGLLMH_03120 5.8e-20 comGE
HEOGLLMH_03121 3e-66 comGF U Putative Competence protein ComGF
HEOGLLMH_03122 2.9e-63 S ComG operon protein 7
HEOGLLMH_03123 2.3e-26 yqzE S YqzE-like protein
HEOGLLMH_03124 3.7e-54 yqzG S Protein of unknown function (DUF3889)
HEOGLLMH_03125 4.2e-121 yqxM
HEOGLLMH_03126 3.5e-71 sipW 3.4.21.89 U Signal peptidase
HEOGLLMH_03127 9.6e-141 tasA S Cell division protein FtsN
HEOGLLMH_03128 7.8e-55 sinR K transcriptional
HEOGLLMH_03129 5.2e-23 sinI S Anti-repressor SinI
HEOGLLMH_03130 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
HEOGLLMH_03131 4.2e-253 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HEOGLLMH_03132 3.4e-55 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HEOGLLMH_03133 2.6e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
HEOGLLMH_03134 2.3e-251 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HEOGLLMH_03135 6.3e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HEOGLLMH_03136 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
HEOGLLMH_03137 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HEOGLLMH_03138 5.7e-70 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HEOGLLMH_03139 5.3e-144 yqhO S esterase of the alpha-beta hydrolase superfamily
HEOGLLMH_03140 3.4e-62 yqhP
HEOGLLMH_03141 6.8e-173 yqhQ S Protein of unknown function (DUF1385)
HEOGLLMH_03143 1.3e-72 yqhR S Conserved membrane protein YqhR
HEOGLLMH_03144 3.3e-176 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HEOGLLMH_03145 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HEOGLLMH_03146 1.8e-36 yqhV S Protein of unknown function (DUF2619)
HEOGLLMH_03147 4.2e-172 spoIIIAA S stage III sporulation protein AA
HEOGLLMH_03148 1.7e-85 spoIIIAB S Stage III sporulation protein
HEOGLLMH_03149 3e-08 spoIIIAC S stage III sporulation protein AC
HEOGLLMH_03150 2.5e-41 spoIIIAD S Stage III sporulation protein AD
HEOGLLMH_03151 6.3e-200 spoIIIAE S stage III sporulation protein AE
HEOGLLMH_03152 2.9e-34 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
HEOGLLMH_03153 1.3e-51 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
HEOGLLMH_03154 6.2e-115 spoIIIAG S stage III sporulation protein AG
HEOGLLMH_03155 1.5e-18 spoIIIAH S SpoIIIAH-like protein
HEOGLLMH_03156 1.4e-31 spoIIIAH S SpoIIIAH-like protein
HEOGLLMH_03157 4.7e-10 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HEOGLLMH_03158 6.7e-41 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HEOGLLMH_03159 2.8e-71 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HEOGLLMH_03160 6.4e-142 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HEOGLLMH_03161 1.1e-66 yqhY S protein conserved in bacteria
HEOGLLMH_03162 2.5e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HEOGLLMH_03163 8e-79 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HEOGLLMH_03164 6e-68 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HEOGLLMH_03165 3.5e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEOGLLMH_03166 8e-37 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEOGLLMH_03167 1.4e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HEOGLLMH_03168 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HEOGLLMH_03169 8.7e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
HEOGLLMH_03170 3.9e-78 argR K Regulates arginine biosynthesis genes
HEOGLLMH_03171 1.3e-117 recN L May be involved in recombinational repair of damaged DNA
HEOGLLMH_03172 3.4e-155 recN L May be involved in recombinational repair of damaged DNA
HEOGLLMH_03173 5.1e-45 rseP 3.4.21.116 M Stage IV sporulation protein B
HEOGLLMH_03174 1.3e-179 rseP 3.4.21.116 M Stage IV sporulation protein B
HEOGLLMH_03175 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HEOGLLMH_03176 1.4e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HEOGLLMH_03179 2.7e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HEOGLLMH_03181 9e-113 K Protein of unknown function (DUF1232)
HEOGLLMH_03182 2.6e-101 ytaF P Probably functions as a manganese efflux pump
HEOGLLMH_03184 4.2e-17
HEOGLLMH_03185 4e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
HEOGLLMH_03186 1.4e-65 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HEOGLLMH_03187 1.5e-39 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HEOGLLMH_03188 4.4e-214 mmgA 2.3.1.9 I Belongs to the thiolase family
HEOGLLMH_03189 2e-152 hbdA 1.1.1.157 I Dehydrogenase
HEOGLLMH_03190 1.8e-102 mmgC I acyl-CoA dehydrogenase
HEOGLLMH_03191 6.1e-91 mmgC I acyl-CoA dehydrogenase
HEOGLLMH_03192 1.3e-207 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
HEOGLLMH_03193 4.9e-276 prpD 4.2.1.79 S 2-methylcitrate dehydratase
HEOGLLMH_03194 3.6e-160 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HEOGLLMH_03195 7e-34 yqzF S Protein of unknown function (DUF2627)
HEOGLLMH_03196 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
HEOGLLMH_03197 4.3e-153 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
HEOGLLMH_03198 2e-205 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
HEOGLLMH_03199 5.4e-122 buk 2.7.2.7 C Belongs to the acetokinase family
HEOGLLMH_03200 8e-64 buk 2.7.2.7 C Belongs to the acetokinase family
HEOGLLMH_03201 2.9e-265 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HEOGLLMH_03202 8.6e-163 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HEOGLLMH_03203 4.6e-185 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HEOGLLMH_03204 8.8e-205 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HEOGLLMH_03205 7.7e-171 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HEOGLLMH_03206 1e-75 yqiW S Belongs to the UPF0403 family
HEOGLLMH_03207 3.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
HEOGLLMH_03208 3.8e-106 artQ E COG0765 ABC-type amino acid transport system, permease component
HEOGLLMH_03209 8.5e-128 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HEOGLLMH_03210 8.2e-171 yqjA S Putative aromatic acid exporter C-terminal domain
HEOGLLMH_03211 3.1e-95 yqjB S protein conserved in bacteria
HEOGLLMH_03213 5.5e-29 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
HEOGLLMH_03214 1.9e-29 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
HEOGLLMH_03215 7.4e-286 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HEOGLLMH_03216 4.2e-40 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HEOGLLMH_03217 4.1e-99 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HEOGLLMH_03218 2.4e-25 yqzJ
HEOGLLMH_03219 3.9e-237 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HEOGLLMH_03220 3.4e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HEOGLLMH_03221 6.1e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HEOGLLMH_03222 1.5e-172 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HEOGLLMH_03223 5e-18 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HEOGLLMH_03224 1.4e-147 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HEOGLLMH_03225 8.2e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HEOGLLMH_03226 8.4e-51 S GlpM protein
HEOGLLMH_03227 2.6e-163 K LysR substrate binding domain
HEOGLLMH_03228 1.6e-94 nusG K Participates in transcription elongation, termination and antitermination
HEOGLLMH_03229 3e-240 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HEOGLLMH_03230 2.9e-176 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HEOGLLMH_03233 4.9e-10 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HEOGLLMH_03234 1.4e-220 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HEOGLLMH_03235 1.6e-129 IQ reductase
HEOGLLMH_03236 0.0 pksJ Q Polyketide synthase of type I
HEOGLLMH_03237 0.0 pksJ Q Polyketide synthase of type I
HEOGLLMH_03238 0.0 pksJ Q Polyketide synthase of type I
HEOGLLMH_03239 0.0 1.1.1.320 Q Polyketide synthase of type I
HEOGLLMH_03240 0.0 Q Polyketide synthase of type I
HEOGLLMH_03241 3.8e-122 Q Polyketide synthase of type I
HEOGLLMH_03242 0.0 pksJ Q Polyketide synthase of type I
HEOGLLMH_03243 0.0 pksJ Q Polyketide synthase of type I
HEOGLLMH_03244 0.0 pksJ Q Polyketide synthase of type I
HEOGLLMH_03245 0.0 pfaA Q Polyketide synthase of type I
HEOGLLMH_03246 1.6e-188 pfaA Q Polyketide synthase of type I
HEOGLLMH_03247 0.0 Q Polyketide synthase of type I
HEOGLLMH_03248 0.0 Q Polyketide synthase of type I
HEOGLLMH_03249 1.1e-93 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HEOGLLMH_03250 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HEOGLLMH_03251 1.7e-279 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HEOGLLMH_03252 1.7e-112 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HEOGLLMH_03253 2.6e-156 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HEOGLLMH_03254 7.6e-160 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HEOGLLMH_03255 3.1e-220 eryK 1.14.13.154 C Cytochrome P450
HEOGLLMH_03256 4.2e-09 pksG 2.3.3.10 I synthase
HEOGLLMH_03257 4.8e-218 pksG 2.3.3.10 I synthase
HEOGLLMH_03258 1.1e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
HEOGLLMH_03259 3.6e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEOGLLMH_03260 7.8e-109 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
HEOGLLMH_03261 3.1e-59 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
HEOGLLMH_03262 3.6e-117 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
HEOGLLMH_03263 1e-259 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HEOGLLMH_03264 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
HEOGLLMH_03265 1.9e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEOGLLMH_03266 4.6e-71 yueF S transporter activity
HEOGLLMH_03268 4.9e-57 S YolD-like protein
HEOGLLMH_03269 1e-234 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HEOGLLMH_03270 3.9e-89 yqjY K acetyltransferase
HEOGLLMH_03271 2.4e-59 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
HEOGLLMH_03272 2.4e-178 yqkA K GrpB protein
HEOGLLMH_03273 2.9e-60 yqkB S Belongs to the HesB IscA family
HEOGLLMH_03274 3.2e-39 yqkC S Protein of unknown function (DUF2552)
HEOGLLMH_03275 2.8e-176 yqkD S COG1073 Hydrolases of the alpha beta superfamily
HEOGLLMH_03277 7.4e-169 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
HEOGLLMH_03278 2.9e-67 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
HEOGLLMH_03279 2.2e-218 yqxK 3.6.4.12 L DNA helicase
HEOGLLMH_03280 7e-59 ansR K Transcriptional regulator
HEOGLLMH_03281 2.9e-187 ansA 3.5.1.1 EJ L-asparaginase
HEOGLLMH_03282 1.1e-267 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
HEOGLLMH_03283 3.3e-120 mleN C Na H antiporter
HEOGLLMH_03284 6e-100 mleN C Na H antiporter
HEOGLLMH_03285 1.1e-105 mleA 1.1.1.38 C malic enzyme
HEOGLLMH_03286 2.7e-50 mleA 1.1.1.38 C malic enzyme
HEOGLLMH_03287 3.3e-22
HEOGLLMH_03288 1.1e-25 yqkK
HEOGLLMH_03289 9.4e-110 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HEOGLLMH_03290 1.9e-80 fur P Belongs to the Fur family
HEOGLLMH_03291 3.7e-37 S Protein of unknown function (DUF4227)
HEOGLLMH_03292 5.1e-125 xerD L recombinase XerD
HEOGLLMH_03293 2.1e-32 xerD L recombinase XerD
HEOGLLMH_03294 3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HEOGLLMH_03295 3.2e-147 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HEOGLLMH_03296 4.5e-132 dacF 3.4.16.4 M Belongs to the peptidase S11 family
HEOGLLMH_03297 4.7e-48 dacF 3.4.16.4 M Belongs to the peptidase S11 family
HEOGLLMH_03298 7.8e-58 spoIIAA T Belongs to the anti-sigma-factor antagonist family
HEOGLLMH_03299 3.9e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HEOGLLMH_03300 1.4e-11 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEOGLLMH_03301 3.7e-114 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEOGLLMH_03302 3.7e-111 spoVAA S Stage V sporulation protein AA
HEOGLLMH_03303 1.5e-30 spoVAB S Stage V sporulation protein AB
HEOGLLMH_03304 1.3e-78 spoVAC S stage V sporulation protein AC
HEOGLLMH_03305 1.4e-40 spoVAD I Stage V sporulation protein AD
HEOGLLMH_03306 5.2e-136 spoVAD I Stage V sporulation protein AD
HEOGLLMH_03307 3.8e-57 spoVAEB S stage V sporulation protein
HEOGLLMH_03308 3.9e-110 spoVAEA S stage V sporulation protein
HEOGLLMH_03309 1.4e-270 spoVAF EG Stage V sporulation protein AF
HEOGLLMH_03310 4.6e-177 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HEOGLLMH_03311 2.3e-62 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HEOGLLMH_03312 5.1e-154 ypuA S Secreted protein
HEOGLLMH_03313 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HEOGLLMH_03314 3.1e-81 ccdC1 O Protein of unknown function (DUF1453)
HEOGLLMH_03315 3.4e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HEOGLLMH_03316 1.7e-49 ypuD
HEOGLLMH_03317 3.4e-208 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HEOGLLMH_03318 8.5e-111 ribE 2.5.1.9 H Riboflavin synthase
HEOGLLMH_03319 3.7e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HEOGLLMH_03320 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HEOGLLMH_03321 3.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEOGLLMH_03322 6e-91 ypuF S Domain of unknown function (DUF309)
HEOGLLMH_03324 3.9e-80 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HEOGLLMH_03325 7.5e-29 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HEOGLLMH_03326 2.3e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HEOGLLMH_03327 1.3e-93 ypuI S Protein of unknown function (DUF3907)
HEOGLLMH_03328 2.2e-126 dacB 3.4.16.4 M Belongs to the peptidase S11 family
HEOGLLMH_03329 1.1e-40 dacB 3.4.16.4 M Belongs to the peptidase S11 family
HEOGLLMH_03330 2e-103 spmA S Spore maturation protein
HEOGLLMH_03331 2.2e-88 spmB S Spore maturation protein
HEOGLLMH_03332 7.6e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HEOGLLMH_03333 4.3e-100 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HEOGLLMH_03334 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
HEOGLLMH_03335 1.9e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HEOGLLMH_03336 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEOGLLMH_03337 1.9e-167 resE 2.7.13.3 T Histidine kinase
HEOGLLMH_03338 1.2e-152 resE 2.7.13.3 T Histidine kinase
HEOGLLMH_03339 9.1e-104 sigX K Belongs to the sigma-70 factor family. ECF subfamily
HEOGLLMH_03340 9.8e-200 rsiX
HEOGLLMH_03341 9.6e-261 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEOGLLMH_03342 6.4e-24 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEOGLLMH_03343 5e-76 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HEOGLLMH_03344 3.6e-41 fer C Ferredoxin
HEOGLLMH_03345 1.7e-148 ypbB 5.1.3.1 S protein conserved in bacteria
HEOGLLMH_03346 2.3e-15 ypbB 5.1.3.1 S protein conserved in bacteria
HEOGLLMH_03347 4.9e-265 recQ 3.6.4.12 L DNA helicase
HEOGLLMH_03348 9.9e-100 ypbD S metal-dependent membrane protease
HEOGLLMH_03349 8.3e-45 ypbE M Lysin motif
HEOGLLMH_03350 9.1e-13 ypbE M Lysin motif
HEOGLLMH_03351 1.3e-51 ypbF S Protein of unknown function (DUF2663)
HEOGLLMH_03352 1.4e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
HEOGLLMH_03353 2e-106 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HEOGLLMH_03354 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HEOGLLMH_03355 6.5e-187 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
HEOGLLMH_03356 3e-26 prsW S Involved in the degradation of specific anti-sigma factors
HEOGLLMH_03357 6.5e-72 prsW S Involved in the degradation of specific anti-sigma factors
HEOGLLMH_03358 7e-161 sleB 3.5.1.28 M Spore cortex-lytic enzyme
HEOGLLMH_03359 6.9e-245 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
HEOGLLMH_03360 7.4e-62 ypfA M Flagellar protein YcgR
HEOGLLMH_03361 1.4e-12 S Family of unknown function (DUF5359)
HEOGLLMH_03362 2.1e-80 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HEOGLLMH_03363 8.3e-21 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HEOGLLMH_03364 2.9e-43 rpsA 1.17.7.4 J Ribosomal protein S1
HEOGLLMH_03365 1.9e-147 rpsA 1.17.7.4 J Ribosomal protein S1
HEOGLLMH_03366 5.9e-186 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HEOGLLMH_03367 4.7e-08 S YpzI-like protein
HEOGLLMH_03368 1.2e-103 yphA
HEOGLLMH_03369 2.9e-11 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HEOGLLMH_03370 2.5e-110 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HEOGLLMH_03371 1.8e-101 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HEOGLLMH_03372 6.6e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HEOGLLMH_03373 1.3e-16 yphE S Protein of unknown function (DUF2768)
HEOGLLMH_03374 6.7e-81 yphF
HEOGLLMH_03375 3.4e-42 yphF
HEOGLLMH_03376 2.2e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HEOGLLMH_03377 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HEOGLLMH_03378 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
HEOGLLMH_03379 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HEOGLLMH_03380 6.2e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HEOGLLMH_03381 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HEOGLLMH_03382 7.4e-197 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HEOGLLMH_03383 2e-79 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HEOGLLMH_03384 9.4e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
HEOGLLMH_03385 9.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HEOGLLMH_03386 1.4e-178 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HEOGLLMH_03387 3.5e-12 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HEOGLLMH_03388 2.4e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HEOGLLMH_03389 9.6e-294 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HEOGLLMH_03390 4.1e-160 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HEOGLLMH_03391 3.4e-16 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HEOGLLMH_03392 1.6e-100 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HEOGLLMH_03393 1.8e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HEOGLLMH_03394 4.9e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HEOGLLMH_03395 1.9e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HEOGLLMH_03396 1.4e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HEOGLLMH_03397 5.9e-89 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HEOGLLMH_03398 4.5e-85 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HEOGLLMH_03399 8.9e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HEOGLLMH_03400 1.4e-234 S COG0457 FOG TPR repeat
HEOGLLMH_03401 2.1e-99 ypiB S Belongs to the UPF0302 family
HEOGLLMH_03402 8.5e-78 ypiF S Protein of unknown function (DUF2487)
HEOGLLMH_03403 9e-127 petB C COG1290 Cytochrome b subunit of the bc complex
HEOGLLMH_03404 1.2e-67 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
HEOGLLMH_03405 9.2e-104 ypjA S membrane
HEOGLLMH_03406 1.2e-25 ypjB S sporulation protein
HEOGLLMH_03407 4.1e-107 ypjB S sporulation protein
HEOGLLMH_03408 2.6e-227 oxdC 4.1.1.2 G Oxalate decarboxylase
HEOGLLMH_03409 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
HEOGLLMH_03410 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
HEOGLLMH_03411 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HEOGLLMH_03412 1.4e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
HEOGLLMH_03413 4.8e-131 bshB1 S proteins, LmbE homologs
HEOGLLMH_03414 4.3e-211 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
HEOGLLMH_03415 5.6e-217 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HEOGLLMH_03416 2.1e-182 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HEOGLLMH_03417 7e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HEOGLLMH_03418 1.2e-41 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HEOGLLMH_03419 3.4e-106 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HEOGLLMH_03420 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HEOGLLMH_03421 2.8e-258 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HEOGLLMH_03422 4.6e-241 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HEOGLLMH_03423 6.7e-23 ypmA S Protein of unknown function (DUF4264)
HEOGLLMH_03424 8.2e-28 ypmB S protein conserved in bacteria
HEOGLLMH_03425 3.3e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HEOGLLMH_03426 9.9e-252 asnS 6.1.1.22 J asparaginyl-tRNA
HEOGLLMH_03427 3e-130 dnaD L DNA replication protein DnaD
HEOGLLMH_03428 1.4e-121 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HEOGLLMH_03429 2.8e-90 ypoC
HEOGLLMH_03430 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HEOGLLMH_03431 4.7e-111 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HEOGLLMH_03432 8.2e-145 yppC S Protein of unknown function (DUF2515)
HEOGLLMH_03433 6.4e-30 yppC S Protein of unknown function (DUF2515)
HEOGLLMH_03438 4.8e-49 yppG S YppG-like protein
HEOGLLMH_03439 1.7e-72 hspX O Belongs to the small heat shock protein (HSP20) family
HEOGLLMH_03440 6.1e-88 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
HEOGLLMH_03441 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HEOGLLMH_03442 4.9e-130 yprB L RNase_H superfamily
HEOGLLMH_03443 9.9e-33 cotD S Inner spore coat protein D
HEOGLLMH_03444 1.7e-99 ypsA S Belongs to the UPF0398 family
HEOGLLMH_03445 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HEOGLLMH_03446 4.9e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HEOGLLMH_03447 6.6e-22 S YpzG-like protein
HEOGLLMH_03449 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
HEOGLLMH_03450 1.1e-275 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HEOGLLMH_03451 6.3e-47 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HEOGLLMH_03452 9.5e-33 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HEOGLLMH_03453 1.3e-235 pbuX F xanthine
HEOGLLMH_03455 2.7e-100 yrdC 3.5.1.19 Q Isochorismatase family
HEOGLLMH_03456 2.2e-79 ydfR S Protein of unknown function (DUF421)
HEOGLLMH_03457 2.8e-38 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
HEOGLLMH_03458 2.7e-106 J Acetyltransferase (GNAT) domain
HEOGLLMH_03459 5.9e-203 bcsA Q Naringenin-chalcone synthase
HEOGLLMH_03460 2.8e-57 ypbQ S protein conserved in bacteria
HEOGLLMH_03461 5.2e-139 ypbR S Dynamin family
HEOGLLMH_03462 4.6e-77 ypbR S Dynamin family
HEOGLLMH_03463 0.0 ypbR S Dynamin family
HEOGLLMH_03464 1e-38 ypbS S Protein of unknown function (DUF2533)
HEOGLLMH_03466 1.4e-164 polA 2.7.7.7 L 5'3' exonuclease
HEOGLLMH_03468 7.1e-68 rnhA 3.1.26.4 L Ribonuclease
HEOGLLMH_03469 3.1e-119 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HEOGLLMH_03470 7e-124 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
HEOGLLMH_03471 1.5e-28 ypeQ S Zinc-finger
HEOGLLMH_03472 1.2e-36 S Protein of unknown function (DUF2564)
HEOGLLMH_03473 3.3e-12 degR
HEOGLLMH_03474 1e-30 cspD K Cold-shock protein
HEOGLLMH_03475 1.7e-215 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HEOGLLMH_03476 3.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HEOGLLMH_03477 1.3e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HEOGLLMH_03478 5.9e-98 ypgQ S phosphohydrolase
HEOGLLMH_03479 2.8e-157 ypgR C COG0694 Thioredoxin-like proteins and domains
HEOGLLMH_03480 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HEOGLLMH_03481 1e-75 yphP S Belongs to the UPF0403 family
HEOGLLMH_03482 7.4e-130 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
HEOGLLMH_03483 2.7e-114 ypjP S YpjP-like protein
HEOGLLMH_03484 8.7e-158 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HEOGLLMH_03485 1.3e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HEOGLLMH_03486 1.4e-115 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HEOGLLMH_03487 3.5e-109 hlyIII S protein, Hemolysin III
HEOGLLMH_03488 6.6e-179 pspF K Transcriptional regulator
HEOGLLMH_03489 4.8e-243 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HEOGLLMH_03490 2.6e-39 ypmP S Protein of unknown function (DUF2535)
HEOGLLMH_03491 1.7e-85 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HEOGLLMH_03492 3.4e-135 ypmR E GDSL-like Lipase/Acylhydrolase
HEOGLLMH_03493 1.6e-97 ypmS S protein conserved in bacteria
HEOGLLMH_03494 4.1e-52 ypoP K transcriptional
HEOGLLMH_03495 3.1e-101 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HEOGLLMH_03496 1.2e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HEOGLLMH_03497 3.2e-123 4.2.1.115 GM Polysaccharide biosynthesis protein
HEOGLLMH_03498 3.7e-56 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
HEOGLLMH_03499 1.6e-117 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
HEOGLLMH_03500 6.7e-181 cgeB S Spore maturation protein
HEOGLLMH_03501 1.6e-52 cgeA
HEOGLLMH_03502 1.7e-42 cgeC
HEOGLLMH_03503 7.7e-249 cgeD M maturation of the outermost layer of the spore
HEOGLLMH_03504 4.9e-145 yiiD K acetyltransferase
HEOGLLMH_03506 1.6e-63 yosT L Bacterial transcription activator, effector binding domain
HEOGLLMH_03507 4.4e-247 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEOGLLMH_03508 2.9e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HEOGLLMH_03509 6.1e-123 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HEOGLLMH_03510 5.1e-256 yodQ 3.5.1.16 E Acetylornithine deacetylase
HEOGLLMH_03511 2.3e-159 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
HEOGLLMH_03512 1.2e-279 kamA 5.4.3.2 E lysine 2,3-aminomutase
HEOGLLMH_03513 8.3e-47 yokU S YokU-like protein, putative antitoxin
HEOGLLMH_03514 4.1e-36 yozE S Belongs to the UPF0346 family
HEOGLLMH_03515 1.7e-125 yodN
HEOGLLMH_03517 6.2e-24 yozD S YozD-like protein
HEOGLLMH_03518 8.9e-102 yodM 3.6.1.27 I Acid phosphatase homologues
HEOGLLMH_03519 1.8e-46 yodL S YodL-like
HEOGLLMH_03521 3.5e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HEOGLLMH_03522 1.9e-14 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HEOGLLMH_03523 1.6e-117 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HEOGLLMH_03524 4.3e-34 yodI
HEOGLLMH_03525 2.8e-128 yodH Q Methyltransferase
HEOGLLMH_03526 1.2e-255 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HEOGLLMH_03527 2.1e-102 yydK K Transcriptional regulator
HEOGLLMH_03528 1.7e-21 yydK K Transcriptional regulator
HEOGLLMH_03529 2.3e-264 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HEOGLLMH_03530 1.5e-194 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
HEOGLLMH_03531 9e-94 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEOGLLMH_03532 1.8e-96 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEOGLLMH_03533 1.3e-08 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEOGLLMH_03534 1e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
HEOGLLMH_03535 7.4e-109 mhqD S Carboxylesterase
HEOGLLMH_03536 4.5e-106 yodC C nitroreductase
HEOGLLMH_03537 3e-56 yodB K transcriptional
HEOGLLMH_03538 7.5e-20 yoaQ S Evidence 4 Homologs of previously reported genes of
HEOGLLMH_03539 9.4e-32 yoaQ S Evidence 4 Homologs of previously reported genes of
HEOGLLMH_03540 2e-67 yodA S tautomerase
HEOGLLMH_03542 1.3e-81 yozR S COG0071 Molecular chaperone (small heat shock protein)
HEOGLLMH_03543 9.9e-39 rarD S -transporter
HEOGLLMH_03544 9.9e-24
HEOGLLMH_03545 9.7e-61 yojF S Protein of unknown function (DUF1806)
HEOGLLMH_03546 2.5e-126 yojG S deacetylase
HEOGLLMH_03547 4.9e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HEOGLLMH_03548 3.7e-241 norM V Multidrug efflux pump
HEOGLLMH_03550 7.4e-112 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HEOGLLMH_03551 5.7e-225 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
HEOGLLMH_03552 3.1e-133 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HEOGLLMH_03553 8.8e-84 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HEOGLLMH_03554 5.9e-111 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HEOGLLMH_03555 3.5e-163 yojN S ATPase family associated with various cellular activities (AAA)
HEOGLLMH_03556 0.0 yojO P Von Willebrand factor
HEOGLLMH_03557 5.1e-14 yojO P Von Willebrand factor
HEOGLLMH_03558 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HEOGLLMH_03559 2.7e-182 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HEOGLLMH_03560 4.8e-142 S Metallo-beta-lactamase superfamily
HEOGLLMH_03561 1.5e-159 yocS S -transporter
HEOGLLMH_03562 3e-29 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HEOGLLMH_03563 9.4e-120 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HEOGLLMH_03564 3.2e-37 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HEOGLLMH_03565 6.6e-80 sodA 1.15.1.1 P Superoxide dismutase
HEOGLLMH_03566 1.4e-66 sodA 1.15.1.1 P Superoxide dismutase
HEOGLLMH_03567 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
HEOGLLMH_03568 1e-136 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
HEOGLLMH_03569 5.1e-142 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
HEOGLLMH_03570 1.6e-31 yozC
HEOGLLMH_03572 2.4e-56 yozO S Bacterial PH domain
HEOGLLMH_03573 8.5e-37 yocN
HEOGLLMH_03574 3.8e-44 yozN
HEOGLLMH_03575 3.2e-52 yocM O Belongs to the small heat shock protein (HSP20) family
HEOGLLMH_03576 2.2e-08
HEOGLLMH_03577 7.8e-10 yocL
HEOGLLMH_03578 1.4e-52 dksA T general stress protein
HEOGLLMH_03580 2.2e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HEOGLLMH_03581 0.0 recQ 3.6.4.12 L DNA helicase
HEOGLLMH_03582 1e-114 yocH CBM50 M COG1388 FOG LysM repeat
HEOGLLMH_03584 3.4e-188 yocD 3.4.17.13 V peptidase S66
HEOGLLMH_03585 1.9e-94 yocC
HEOGLLMH_03586 1.8e-12 yocB J Protein required for attachment to host cells
HEOGLLMH_03587 1.6e-103 yocB J Protein required for attachment to host cells
HEOGLLMH_03588 1.1e-54 yozB S membrane
HEOGLLMH_03589 5.5e-121 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HEOGLLMH_03590 1.7e-54 czrA K transcriptional
HEOGLLMH_03591 1.9e-92 yobW
HEOGLLMH_03592 2.2e-136 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
HEOGLLMH_03593 3.7e-94 yobS K Transcriptional regulator
HEOGLLMH_03594 3.5e-134 yobQ K helix_turn_helix, arabinose operon control protein
HEOGLLMH_03595 4.9e-54 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
HEOGLLMH_03596 1.5e-75 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HEOGLLMH_03597 2e-173 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HEOGLLMH_03598 7.4e-77 S SMI1-KNR4 cell-wall
HEOGLLMH_03599 1.9e-44
HEOGLLMH_03600 1.3e-31 hpr K helix_turn_helix multiple antibiotic resistance protein
HEOGLLMH_03601 2.2e-25 hpr K helix_turn_helix multiple antibiotic resistance protein
HEOGLLMH_03602 1.9e-07 hpr K helix_turn_helix multiple antibiotic resistance protein
HEOGLLMH_03604 3.2e-77 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEOGLLMH_03605 1.4e-144 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEOGLLMH_03606 1.9e-112 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEOGLLMH_03607 3.7e-193 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEOGLLMH_03608 9.1e-278 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
HEOGLLMH_03609 2.3e-166 yoaB EGP Major facilitator Superfamily
HEOGLLMH_03610 1.6e-79 yoxB
HEOGLLMH_03611 9.4e-47 yoxB
HEOGLLMH_03612 7.5e-41 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HEOGLLMH_03613 5.2e-125 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HEOGLLMH_03614 2.6e-32 lipB 2.3.1.181 K Acetyltransferase (GNAT) domain
HEOGLLMH_03615 1.4e-15 lipB 2.3.1.181 K Acetyltransferase (GNAT) domain
HEOGLLMH_03616 1e-61 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HEOGLLMH_03617 3e-122 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEOGLLMH_03618 1e-148 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HEOGLLMH_03619 7.7e-42 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HEOGLLMH_03620 3.9e-146 gltC K Transcriptional regulator
HEOGLLMH_03621 5.1e-59 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
HEOGLLMH_03622 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
HEOGLLMH_03623 1.1e-291 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HEOGLLMH_03625 4.5e-188 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HEOGLLMH_03626 4.9e-154 gltR1 K Transcriptional regulator
HEOGLLMH_03627 6.6e-15 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HEOGLLMH_03628 1.8e-50 ybzH K Helix-turn-helix domain
HEOGLLMH_03629 9.4e-201 ybcL EGP Major facilitator Superfamily
HEOGLLMH_03630 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HEOGLLMH_03631 1.8e-34 yoeD G Helix-turn-helix domain
HEOGLLMH_03632 3.5e-97 L Integrase
HEOGLLMH_03634 9e-98 yoeB S IseA DL-endopeptidase inhibitor
HEOGLLMH_03635 2.7e-247 yoeA V MATE efflux family protein
HEOGLLMH_03636 1.5e-188 yoxA 5.1.3.3 G Aldose 1-epimerase
HEOGLLMH_03637 3e-268 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
HEOGLLMH_03638 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEOGLLMH_03639 6.7e-274 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEOGLLMH_03640 4.7e-249 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEOGLLMH_03641 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEOGLLMH_03642 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEOGLLMH_03643 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEOGLLMH_03644 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEOGLLMH_03645 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEOGLLMH_03646 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
HEOGLLMH_03647 6e-64 yngL S Protein of unknown function (DUF1360)
HEOGLLMH_03648 9.8e-307 yngK T Glycosyl hydrolase-like 10
HEOGLLMH_03649 2.8e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
HEOGLLMH_03650 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HEOGLLMH_03651 9.3e-253 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
HEOGLLMH_03652 2.4e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
HEOGLLMH_03653 4.3e-169 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
HEOGLLMH_03654 1.5e-138 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HEOGLLMH_03655 1.1e-289 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HEOGLLMH_03656 4.1e-104 yngC S SNARE associated Golgi protein
HEOGLLMH_03657 2.7e-160 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HEOGLLMH_03658 3.7e-72 yngA S membrane
HEOGLLMH_03659 2.1e-148 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HEOGLLMH_03660 1.9e-261 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HEOGLLMH_03661 2.1e-213 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HEOGLLMH_03662 9.8e-129 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HEOGLLMH_03663 9.7e-194 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HEOGLLMH_03664 2e-169 bioI 1.14.14.46 C Cytochrome P450
HEOGLLMH_03665 1.4e-251 yxjC EG COG2610 H gluconate symporter and related permeases
HEOGLLMH_03666 1.3e-128 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HEOGLLMH_03667 2.4e-121 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HEOGLLMH_03668 6.9e-139 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HEOGLLMH_03669 1.1e-223 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HEOGLLMH_03670 2e-302 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEOGLLMH_03671 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEOGLLMH_03672 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEOGLLMH_03673 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEOGLLMH_03674 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEOGLLMH_03675 3.2e-99 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEOGLLMH_03676 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEOGLLMH_03677 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEOGLLMH_03678 3.5e-288 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
HEOGLLMH_03679 2.2e-251 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
HEOGLLMH_03680 1.8e-41 T Transcriptional regulatory protein, C terminal
HEOGLLMH_03681 1.3e-34 T Transcriptional regulatory protein, C terminal
HEOGLLMH_03682 3.5e-234 T PhoQ Sensor
HEOGLLMH_03683 1.3e-51 S Domain of unknown function (DUF4870)
HEOGLLMH_03684 2.1e-210 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
HEOGLLMH_03685 8.5e-215 S Platelet-activating factor acetylhydrolase, isoform II
HEOGLLMH_03686 1.2e-10
HEOGLLMH_03688 7.5e-64 V ABC transporter
HEOGLLMH_03689 4.6e-32 S bacteriocin-associated integral membrane protein
HEOGLLMH_03690 1.3e-48
HEOGLLMH_03691 3.4e-272 yndJ S YndJ-like protein
HEOGLLMH_03692 3.1e-78 yndH S Domain of unknown function (DUF4166)
HEOGLLMH_03693 1.2e-159 yndG S DoxX-like family
HEOGLLMH_03694 2.9e-224 exuT G Sugar (and other) transporter
HEOGLLMH_03695 1.1e-181 kdgR_1 K transcriptional
HEOGLLMH_03696 3e-148 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HEOGLLMH_03697 6.8e-214 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HEOGLLMH_03698 3.1e-113 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
HEOGLLMH_03699 1.4e-192 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
HEOGLLMH_03700 2e-180 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
HEOGLLMH_03701 3.5e-250 agcS E Sodium alanine symporter
HEOGLLMH_03702 1.6e-13
HEOGLLMH_03703 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEOGLLMH_03704 5.9e-70 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEOGLLMH_03705 2.2e-42 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEOGLLMH_03706 5.2e-218 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEOGLLMH_03707 1.5e-68 yccU S CoA-binding protein
HEOGLLMH_03708 8.5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HEOGLLMH_03709 1.3e-50 yneR S Belongs to the HesB IscA family
HEOGLLMH_03710 4.4e-54 yneQ
HEOGLLMH_03711 8.3e-75 yneP S Thioesterase-like superfamily
HEOGLLMH_03712 2.7e-33 tlp S Belongs to the Tlp family
HEOGLLMH_03715 1.2e-88 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HEOGLLMH_03716 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HEOGLLMH_03717 7.5e-15 sspO S Belongs to the SspO family
HEOGLLMH_03718 2.3e-19 sspP S Belongs to the SspP family
HEOGLLMH_03719 2.9e-63 hspX O Spore coat protein
HEOGLLMH_03720 8.5e-75 yneK S Protein of unknown function (DUF2621)
HEOGLLMH_03721 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
HEOGLLMH_03722 4.7e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
HEOGLLMH_03723 1.7e-125 ccdA O cytochrome c biogenesis protein
HEOGLLMH_03724 2.9e-23 ynzD S Spo0E like sporulation regulatory protein
HEOGLLMH_03725 2.3e-28 yneF S UPF0154 protein
HEOGLLMH_03726 1.3e-81 yneE S Sporulation inhibitor of replication protein sirA
HEOGLLMH_03727 1.1e-138 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HEOGLLMH_03728 7.7e-217 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HEOGLLMH_03729 9.8e-33 ynzC S UPF0291 protein
HEOGLLMH_03730 3.5e-112 yneB L resolvase
HEOGLLMH_03731 6.2e-51 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HEOGLLMH_03732 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HEOGLLMH_03733 4.6e-12 yoaW
HEOGLLMH_03734 1e-70 yndM S Protein of unknown function (DUF2512)
HEOGLLMH_03735 2.1e-138 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
HEOGLLMH_03736 1.6e-07
HEOGLLMH_03737 5.3e-142 yndL S Replication protein
HEOGLLMH_03738 2.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HEOGLLMH_03739 0.0 yobO M Pectate lyase superfamily protein
HEOGLLMH_03741 3.5e-94 yvgO
HEOGLLMH_03743 1.2e-117 AA10,CBM73 S Pfam:Chitin_bind_3
HEOGLLMH_03744 5.3e-173 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEOGLLMH_03745 1.7e-32 ynaE S Domain of unknown function (DUF3885)
HEOGLLMH_03746 3.6e-46 ynaE S Domain of unknown function (DUF3885)
HEOGLLMH_03747 1.8e-19 ynaE S Domain of unknown function (DUF3885)
HEOGLLMH_03749 3e-59
HEOGLLMH_03750 2.1e-59 J Acetyltransferase (GNAT) domain
HEOGLLMH_03751 3.3e-146 yoaP 3.1.3.18 K YoaP-like
HEOGLLMH_03753 3.4e-20 yoaW
HEOGLLMH_03754 3.9e-187 adhP 1.1.1.1 C alcohol dehydrogenase
HEOGLLMH_03755 3e-23 dinB S DinB family
HEOGLLMH_03756 1.4e-37 S DinB family
HEOGLLMH_03757 2.8e-36 K WYL domain
HEOGLLMH_03758 1.9e-50 K WYL domain
HEOGLLMH_03763 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
HEOGLLMH_03764 9e-289 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
HEOGLLMH_03765 4.9e-262 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HEOGLLMH_03766 3.5e-216 xylR GK ROK family
HEOGLLMH_03767 3.8e-223 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HEOGLLMH_03768 5e-68 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HEOGLLMH_03769 3.4e-250 xynT G MFS/sugar transport protein
HEOGLLMH_03770 7.6e-213 mrjp G Major royal jelly protein
HEOGLLMH_03771 1.9e-261 glnA 6.3.1.2 E glutamine synthetase
HEOGLLMH_03772 5.2e-27 glnR K transcriptional
HEOGLLMH_03773 8.4e-27 glnR K transcriptional
HEOGLLMH_03774 8.2e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HEOGLLMH_03775 1.1e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HEOGLLMH_03776 1.3e-176 spoVK O stage V sporulation protein K
HEOGLLMH_03777 1.9e-114 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HEOGLLMH_03778 3.8e-108 ymaB S MutT family
HEOGLLMH_03779 7.1e-65 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEOGLLMH_03780 2.5e-79 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEOGLLMH_03781 8.8e-209 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEOGLLMH_03782 4.6e-188 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEOGLLMH_03783 1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HEOGLLMH_03784 6.9e-18 ymzA
HEOGLLMH_03785 8.5e-44
HEOGLLMH_03786 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HEOGLLMH_03787 6.7e-173 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HEOGLLMH_03788 1.4e-47 ymaF S YmaF family
HEOGLLMH_03790 3.1e-48 ebrA P Small Multidrug Resistance protein
HEOGLLMH_03791 1.2e-53 ebrB P Small Multidrug Resistance protein
HEOGLLMH_03792 6e-79 ymaD O redox protein, regulator of disulfide bond formation
HEOGLLMH_03793 1.2e-126 ymaC S Replication protein
HEOGLLMH_03795 3e-256 aprX O Belongs to the peptidase S8 family
HEOGLLMH_03796 1.4e-62 ymzB
HEOGLLMH_03797 6.4e-71 yoaK S Membrane
HEOGLLMH_03798 1.1e-60 nucB M Deoxyribonuclease NucA/NucB
HEOGLLMH_03799 4.5e-230 cypA C Cytochrome P450
HEOGLLMH_03800 0.0 pks13 HQ Beta-ketoacyl synthase
HEOGLLMH_03801 1.4e-267 dhbF IQ polyketide synthase
HEOGLLMH_03802 0.0 dhbF IQ polyketide synthase
HEOGLLMH_03803 0.0 dhbF IQ polyketide synthase
HEOGLLMH_03804 8.3e-137 dhbF IQ polyketide synthase
HEOGLLMH_03805 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
HEOGLLMH_03806 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
HEOGLLMH_03807 8.9e-92 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
HEOGLLMH_03808 8e-137 Q Polyketide synthase of type I
HEOGLLMH_03809 1.7e-134 Q Polyketide synthase of type I
HEOGLLMH_03810 0.0 Q Polyketide synthase of type I
HEOGLLMH_03811 0.0 Q Polyketide synthase of type I
HEOGLLMH_03812 3.5e-307 rhiB IQ polyketide synthase
HEOGLLMH_03813 1.2e-132 rhiB IQ polyketide synthase
HEOGLLMH_03814 0.0 rhiB IQ polyketide synthase
HEOGLLMH_03815 1.1e-109 pksI I Belongs to the enoyl-CoA hydratase isomerase family
HEOGLLMH_03816 1.5e-16 pksI I Belongs to the enoyl-CoA hydratase isomerase family
HEOGLLMH_03817 6.3e-145 pksH 4.2.1.18 I enoyl-CoA hydratase
HEOGLLMH_03818 1.1e-242 pksG 2.3.3.10 I synthase
HEOGLLMH_03819 6.5e-35 acpK IQ Phosphopantetheine attachment site
HEOGLLMH_03820 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HEOGLLMH_03821 3.3e-183 pksD Q Acyl transferase domain
HEOGLLMH_03822 2e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HEOGLLMH_03823 1.6e-117 pksB 3.1.2.6 S Polyketide biosynthesis
HEOGLLMH_03825 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HEOGLLMH_03826 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HEOGLLMH_03827 1.7e-88 cotE S Spore coat protein
HEOGLLMH_03828 5.1e-31 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HEOGLLMH_03830 4.5e-32 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HEOGLLMH_03831 6.4e-173 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HEOGLLMH_03832 1.5e-68 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HEOGLLMH_03833 1.3e-213 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HEOGLLMH_03834 2.8e-196 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HEOGLLMH_03835 1.2e-36 spoVS S Stage V sporulation protein S
HEOGLLMH_03836 4.9e-153 ymdB S protein conserved in bacteria
HEOGLLMH_03837 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
HEOGLLMH_03838 5e-194 pbpX V Beta-lactamase
HEOGLLMH_03839 6.2e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HEOGLLMH_03840 1.9e-231 cinA 3.5.1.42 S Belongs to the CinA family
HEOGLLMH_03841 3.8e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HEOGLLMH_03842 2.1e-123 ymfM S protein conserved in bacteria
HEOGLLMH_03843 3.5e-143 ymfK S Protein of unknown function (DUF3388)
HEOGLLMH_03844 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
HEOGLLMH_03845 4.6e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HEOGLLMH_03846 4.8e-207 ymfH S zinc protease
HEOGLLMH_03847 1.2e-238 ymfF S Peptidase M16
HEOGLLMH_03848 1.1e-143 ydgH S drug exporters of the RND superfamily
HEOGLLMH_03849 6.1e-294 ydgH S drug exporters of the RND superfamily
HEOGLLMH_03850 1.8e-75 K helix_turn_helix multiple antibiotic resistance protein
HEOGLLMH_03851 6.8e-224 ymfD EGP Major facilitator Superfamily
HEOGLLMH_03852 1.8e-133 ymfC K Transcriptional regulator
HEOGLLMH_03853 1.3e-239 ftsK D Belongs to the FtsK SpoIIIE SftA family
HEOGLLMH_03854 1e-90 ftsK D Belongs to the FtsK SpoIIIE SftA family
HEOGLLMH_03855 6.3e-31 S YlzJ-like protein
HEOGLLMH_03856 2.9e-131 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
HEOGLLMH_03857 1.2e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEOGLLMH_03858 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HEOGLLMH_03859 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HEOGLLMH_03860 7.6e-194 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HEOGLLMH_03861 1.4e-53 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HEOGLLMH_03862 1.1e-22 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HEOGLLMH_03863 3.6e-160 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
HEOGLLMH_03864 2.6e-42 ymxH S YlmC YmxH family
HEOGLLMH_03865 3.6e-235 pepR S Belongs to the peptidase M16 family
HEOGLLMH_03866 8e-182 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
HEOGLLMH_03867 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HEOGLLMH_03868 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HEOGLLMH_03869 3.5e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HEOGLLMH_03870 3.1e-170 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HEOGLLMH_03871 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HEOGLLMH_03872 3.9e-44 ylxP S protein conserved in bacteria
HEOGLLMH_03873 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HEOGLLMH_03874 1.8e-47 ylxQ J ribosomal protein
HEOGLLMH_03875 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
HEOGLLMH_03876 5.6e-206 nusA K Participates in both transcription termination and antitermination
HEOGLLMH_03877 1.5e-80 rimP S Required for maturation of 30S ribosomal subunits
HEOGLLMH_03878 3.4e-191 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEOGLLMH_03879 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEOGLLMH_03880 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HEOGLLMH_03881 1e-232 rasP M zinc metalloprotease
HEOGLLMH_03882 3.6e-213 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HEOGLLMH_03883 8.2e-101 cdsA 2.7.7.41 S Belongs to the CDS family
HEOGLLMH_03884 2.6e-141 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HEOGLLMH_03885 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HEOGLLMH_03886 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HEOGLLMH_03887 5.3e-156 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HEOGLLMH_03888 1.4e-130 rpsB J Belongs to the universal ribosomal protein uS2 family
HEOGLLMH_03889 3.1e-54 ylxL
HEOGLLMH_03890 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEOGLLMH_03891 5.1e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HEOGLLMH_03892 1.8e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HEOGLLMH_03893 8.8e-81 cheW NT COG0835 Chemotaxis signal transduction protein
HEOGLLMH_03894 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
HEOGLLMH_03895 1.3e-193 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HEOGLLMH_03896 7.8e-155 flhG D Belongs to the ParA family
HEOGLLMH_03897 7.9e-194 flhF N Flagellar biosynthesis regulator FlhF
HEOGLLMH_03898 1.6e-253 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HEOGLLMH_03899 5.6e-77 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HEOGLLMH_03900 3e-78 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HEOGLLMH_03901 6.9e-102 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HEOGLLMH_03902 1.6e-92 fliR N Flagellar biosynthetic protein FliR
HEOGLLMH_03903 2e-37 fliQ N Role in flagellar biosynthesis
HEOGLLMH_03904 4.3e-110 fliP N Plays a role in the flagellum-specific transport system
HEOGLLMH_03905 2e-68 fliZ N Flagellar biosynthesis protein, FliO
HEOGLLMH_03906 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
HEOGLLMH_03907 2.7e-189 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HEOGLLMH_03908 2.4e-133 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HEOGLLMH_03909 3.6e-09 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HEOGLLMH_03910 7.8e-57 fliL N Controls the rotational direction of flagella during chemotaxis
HEOGLLMH_03911 3.4e-32 flbD N protein, possibly involved in motility
HEOGLLMH_03912 4e-139 flgG N Flagellar basal body rod
HEOGLLMH_03913 1.4e-72 flgD N Flagellar basal body rod modification protein
HEOGLLMH_03914 7.5e-202 fliK N Flagellar hook-length control protein
HEOGLLMH_03916 1.1e-33 ylxF S MgtE intracellular N domain
HEOGLLMH_03917 4.5e-71 fliJ N Flagellar biosynthesis chaperone
HEOGLLMH_03918 5.5e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HEOGLLMH_03919 3.7e-89 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
HEOGLLMH_03920 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HEOGLLMH_03921 1.4e-263 fliF N The M ring may be actively involved in energy transduction
HEOGLLMH_03922 2.5e-31 fliE N Flagellar hook-basal body
HEOGLLMH_03923 9e-75 flgC N Belongs to the flagella basal body rod proteins family
HEOGLLMH_03924 3e-55 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HEOGLLMH_03925 1.6e-129 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HEOGLLMH_03926 4.3e-165 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HEOGLLMH_03927 6.8e-57 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HEOGLLMH_03928 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HEOGLLMH_03929 2.1e-115 xerC L tyrosine recombinase XerC
HEOGLLMH_03930 1.6e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HEOGLLMH_03931 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HEOGLLMH_03932 4.8e-78 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
HEOGLLMH_03933 1.6e-73 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
HEOGLLMH_03934 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HEOGLLMH_03935 1.3e-210 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HEOGLLMH_03936 6.7e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
HEOGLLMH_03937 9.8e-308 ylqG
HEOGLLMH_03938 3.2e-125 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEOGLLMH_03939 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HEOGLLMH_03940 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HEOGLLMH_03941 2.7e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HEOGLLMH_03942 1.7e-76 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HEOGLLMH_03943 2.2e-61 ylqD S YlqD protein
HEOGLLMH_03944 1.7e-35 ylqC S Belongs to the UPF0109 family
HEOGLLMH_03945 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HEOGLLMH_03946 1.9e-169 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HEOGLLMH_03947 3e-45 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HEOGLLMH_03948 9e-32 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HEOGLLMH_03949 7.8e-68 S Phosphotransferase enzyme family
HEOGLLMH_03950 4e-51 S Phosphotransferase enzyme family
HEOGLLMH_03951 5.9e-155 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HEOGLLMH_03953 0.0 smc D Required for chromosome condensation and partitioning
HEOGLLMH_03954 1.8e-62 smc D Required for chromosome condensation and partitioning
HEOGLLMH_03955 9.9e-83 smc D Required for chromosome condensation and partitioning
HEOGLLMH_03956 8.7e-116 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HEOGLLMH_03957 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEOGLLMH_03958 4.6e-129 IQ reductase
HEOGLLMH_03959 7e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HEOGLLMH_03960 3.6e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HEOGLLMH_03961 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HEOGLLMH_03962 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HEOGLLMH_03963 4.6e-155 sdaAA 4.3.1.17 E L-serine dehydratase
HEOGLLMH_03964 1.6e-117 sdaAB 4.3.1.17 E L-serine dehydratase
HEOGLLMH_03965 2.3e-301 yloV S kinase related to dihydroxyacetone kinase
HEOGLLMH_03966 5.5e-59 asp S protein conserved in bacteria
HEOGLLMH_03967 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HEOGLLMH_03968 1.8e-07 S Stage V sporulation protein family
HEOGLLMH_03969 4e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
HEOGLLMH_03970 1.4e-116 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HEOGLLMH_03971 5.7e-166 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HEOGLLMH_03972 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HEOGLLMH_03973 8.7e-139 stp 3.1.3.16 T phosphatase
HEOGLLMH_03974 9e-206 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HEOGLLMH_03975 1.7e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HEOGLLMH_03976 1e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HEOGLLMH_03977 6e-85 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HEOGLLMH_03978 2.2e-173 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HEOGLLMH_03979 1.9e-270 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HEOGLLMH_03980 3.3e-225 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HEOGLLMH_03981 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HEOGLLMH_03982 8.1e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HEOGLLMH_03983 1.5e-40 ylzA S Belongs to the UPF0296 family
HEOGLLMH_03984 1e-154 yloC S stress-induced protein
HEOGLLMH_03985 1.7e-235 yloB 3.6.3.8 P COG0474 Cation transport ATPase
HEOGLLMH_03986 1.9e-245 yloB 3.6.3.8 P COG0474 Cation transport ATPase
HEOGLLMH_03987 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HEOGLLMH_03988 3.4e-80 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
HEOGLLMH_03989 5.8e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
HEOGLLMH_03990 2.4e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HEOGLLMH_03991 2.5e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
HEOGLLMH_03992 2.3e-144 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HEOGLLMH_03993 6.9e-42 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HEOGLLMH_03995 1.8e-179 cysP P phosphate transporter
HEOGLLMH_03996 2e-90 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HEOGLLMH_03997 2.1e-41 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HEOGLLMH_03999 9.8e-16 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HEOGLLMH_04000 1.7e-31 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HEOGLLMH_04001 2.1e-19 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HEOGLLMH_04002 4.2e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HEOGLLMH_04003 2.2e-85 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HEOGLLMH_04004 1.1e-74 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HEOGLLMH_04005 4.6e-76 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HEOGLLMH_04006 7.9e-143 carB 6.3.5.5 F Belongs to the CarB family
HEOGLLMH_04007 3.2e-107 carB 6.3.5.5 F Belongs to the CarB family
HEOGLLMH_04008 1.5e-107 carB 6.3.5.5 F Belongs to the CarB family
HEOGLLMH_04009 1.5e-71 carB 6.3.5.5 F Belongs to the CarB family
HEOGLLMH_04010 7.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HEOGLLMH_04011 6.9e-172 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HEOGLLMH_04012 2e-33 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HEOGLLMH_04013 1.5e-169 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HEOGLLMH_04014 3.6e-233 pyrP F Xanthine uracil
HEOGLLMH_04015 1e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HEOGLLMH_04016 1.4e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HEOGLLMH_04017 5.2e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HEOGLLMH_04018 3.4e-64 dksA T COG1734 DnaK suppressor protein
HEOGLLMH_04019 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HEOGLLMH_04020 8.9e-68 divIVA D Cell division initiation protein
HEOGLLMH_04021 1.6e-140 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
HEOGLLMH_04022 5.2e-41 yggT S membrane
HEOGLLMH_04023 1.5e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HEOGLLMH_04024 2.1e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HEOGLLMH_04025 1.5e-160 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
HEOGLLMH_04026 2.2e-38 ylmC S sporulation protein
HEOGLLMH_04027 2.7e-254 argE 3.5.1.16 E Acetylornithine deacetylase
HEOGLLMH_04029 3e-136 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HEOGLLMH_04030 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEOGLLMH_04031 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEOGLLMH_04032 8.5e-148 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HEOGLLMH_04033 0.0 bpr O COG1404 Subtilisin-like serine proteases
HEOGLLMH_04034 1.3e-202 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HEOGLLMH_04035 1.6e-144 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HEOGLLMH_04036 2.7e-74 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HEOGLLMH_04037 3e-134 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HEOGLLMH_04038 9.5e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HEOGLLMH_04039 1.3e-196 spoVE D Belongs to the SEDS family
HEOGLLMH_04040 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HEOGLLMH_04041 1.7e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HEOGLLMH_04042 7.5e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HEOGLLMH_04043 2.1e-285 ftsI 3.4.16.4 M stage V sporulation protein D
HEOGLLMH_04044 2.8e-62 ftsI 3.4.16.4 M stage V sporulation protein D
HEOGLLMH_04045 1.1e-253 ftsI 3.4.16.4 M Penicillin-binding Protein
HEOGLLMH_04046 4.6e-132 ftsI 3.4.16.4 M Penicillin-binding Protein
HEOGLLMH_04047 2.9e-52 ftsL D Essential cell division protein
HEOGLLMH_04048 2.5e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HEOGLLMH_04049 8.9e-78 mraZ K Belongs to the MraZ family
HEOGLLMH_04050 2.1e-272 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HEOGLLMH_04051 6.1e-163 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HEOGLLMH_04052 1.2e-88 ylbP K n-acetyltransferase
HEOGLLMH_04053 2e-10 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HEOGLLMH_04054 1.2e-65 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HEOGLLMH_04055 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HEOGLLMH_04056 1e-90 yceD S metal-binding, possibly nucleic acid-binding protein
HEOGLLMH_04058 2.7e-208 ylbM S Belongs to the UPF0348 family
HEOGLLMH_04059 1.9e-77 ylbL T Belongs to the peptidase S16 family
HEOGLLMH_04060 4e-90 ylbL T Belongs to the peptidase S16 family
HEOGLLMH_04061 2e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
HEOGLLMH_04062 2.2e-216 ylbJ S Sporulation integral membrane protein YlbJ
HEOGLLMH_04063 8e-16 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HEOGLLMH_04064 2.3e-41 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HEOGLLMH_04065 1.2e-97 rsmD 2.1.1.171 L Methyltransferase
HEOGLLMH_04066 1.2e-42 ylbG S UPF0298 protein
HEOGLLMH_04067 7.8e-71 ylbF S Belongs to the UPF0342 family
HEOGLLMH_04068 8.8e-37 ylbE S YlbE-like protein
HEOGLLMH_04069 6.5e-56 ylbD S Putative coat protein
HEOGLLMH_04070 2.1e-199 ylbC S protein with SCP PR1 domains
HEOGLLMH_04071 3.7e-73 ylbB T COG0517 FOG CBS domain
HEOGLLMH_04072 8.5e-60 ylbA S YugN-like family
HEOGLLMH_04073 8.2e-165 ctaG S cytochrome c oxidase
HEOGLLMH_04074 2.7e-52 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HEOGLLMH_04075 2.4e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HEOGLLMH_04076 2.5e-103 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HEOGLLMH_04077 9.5e-242 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HEOGLLMH_04078 2.2e-66 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HEOGLLMH_04079 2.3e-86 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HEOGLLMH_04080 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HEOGLLMH_04081 1.6e-132 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HEOGLLMH_04082 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HEOGLLMH_04083 2.8e-252 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HEOGLLMH_04084 1.5e-25 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HEOGLLMH_04085 1.6e-136 ftsW D Belongs to the SEDS family
HEOGLLMH_04086 8.7e-44 ylaN S Belongs to the UPF0358 family
HEOGLLMH_04087 5.3e-161 glsA 3.5.1.2 E Belongs to the glutaminase family
HEOGLLMH_04088 1.6e-10 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HEOGLLMH_04089 1.1e-33 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HEOGLLMH_04090 2.5e-175 phoH T ATPase related to phosphate starvation-inducible protein PhoH
HEOGLLMH_04091 2.4e-53 phoH T ATPase related to phosphate starvation-inducible protein PhoH
HEOGLLMH_04092 3.3e-104 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HEOGLLMH_04093 1e-33 ylaI S protein conserved in bacteria
HEOGLLMH_04094 1.3e-48 ylaH S YlaH-like protein
HEOGLLMH_04095 0.0 typA T GTP-binding protein TypA
HEOGLLMH_04096 4.3e-19 S Family of unknown function (DUF5325)
HEOGLLMH_04097 1.1e-35 ylaE
HEOGLLMH_04098 2.8e-13 sigC S Putative zinc-finger
HEOGLLMH_04099 2.7e-296 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
HEOGLLMH_04100 4e-83 ykzC S Acetyltransferase (GNAT) family
HEOGLLMH_04101 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
HEOGLLMH_04102 6.3e-24 ykzI
HEOGLLMH_04103 4.9e-119 yktB S Belongs to the UPF0637 family
HEOGLLMH_04104 4.5e-42 yktA S Belongs to the UPF0223 family
HEOGLLMH_04105 3.1e-278 speA 4.1.1.19 E Arginine
HEOGLLMH_04106 3e-36 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
HEOGLLMH_04107 5.2e-91 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
HEOGLLMH_04108 9.2e-42 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
HEOGLLMH_04109 5e-241 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HEOGLLMH_04110 4.9e-230 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HEOGLLMH_04111 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HEOGLLMH_04112 2.7e-205 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HEOGLLMH_04113 1e-209 V Beta-lactamase
HEOGLLMH_04114 1.4e-158 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
HEOGLLMH_04115 1.6e-39 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
HEOGLLMH_04116 5.8e-214 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
HEOGLLMH_04117 1.2e-253 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
HEOGLLMH_04118 0.0 Q Polyketide synthase of type I
HEOGLLMH_04119 0.0 Q Polyketide synthase of type I
HEOGLLMH_04120 0.0 Q Polyketide synthase of type I
HEOGLLMH_04121 1.8e-25 Q Polyketide synthase of type I
HEOGLLMH_04122 1.4e-124 Q Polyketide synthase of type I
HEOGLLMH_04123 6.7e-23 Q Polyketide synthase of type I
HEOGLLMH_04124 7.2e-43 Q Polyketide synthase of type I
HEOGLLMH_04125 0.0 Q Polyketide synthase of type I
HEOGLLMH_04126 5.8e-149 Q Polyketide synthase of type I
HEOGLLMH_04127 0.0 Q Polyketide synthase of type I
HEOGLLMH_04128 0.0 Q Polyketide synthase of type I
HEOGLLMH_04129 3.2e-259 Q Polyketide synthase of type I
HEOGLLMH_04130 4.6e-132 Q Polyketide synthase of type I
HEOGLLMH_04131 0.0 Q polyketide synthase
HEOGLLMH_04132 7.2e-80 Q polyketide synthase
HEOGLLMH_04133 8.8e-82 Q polyketide synthase
HEOGLLMH_04134 5.4e-139 Q polyketide synthase
HEOGLLMH_04135 3e-17 Q polyketide synthase
HEOGLLMH_04136 0.0 Q Polyketide synthase of type I
HEOGLLMH_04137 0.0 Q Polyketide synthase of type I
HEOGLLMH_04138 0.0 Q Polyketide synthase of type I
HEOGLLMH_04139 1.2e-111 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HEOGLLMH_04140 2.2e-199 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HEOGLLMH_04141 1.4e-72 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HEOGLLMH_04142 1.1e-31 recN L Putative cell-wall binding lipoprotein
HEOGLLMH_04143 9.9e-41 recN L Putative cell-wall binding lipoprotein
HEOGLLMH_04145 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HEOGLLMH_04146 1e-147 ykrA S hydrolases of the HAD superfamily
HEOGLLMH_04147 8.2e-31 ykzG S Belongs to the UPF0356 family
HEOGLLMH_04148 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEOGLLMH_04149 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HEOGLLMH_04150 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
HEOGLLMH_04151 4.1e-150 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
HEOGLLMH_04152 4e-246 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
HEOGLLMH_04153 2.1e-45 abrB K of stationary sporulation gene expression
HEOGLLMH_04154 6.9e-184 mreB D Rod-share determining protein MreBH
HEOGLLMH_04155 5.5e-12 S Uncharacterized protein YkpC
HEOGLLMH_04156 8.6e-237 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HEOGLLMH_04157 5.3e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HEOGLLMH_04158 2.2e-309 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HEOGLLMH_04159 4.4e-37 ykoA
HEOGLLMH_04160 2.9e-36 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HEOGLLMH_04161 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HEOGLLMH_04162 1e-38 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
HEOGLLMH_04163 5.6e-112 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
HEOGLLMH_04164 9.2e-133 fruR K Transcriptional regulator
HEOGLLMH_04165 5.2e-99 yknZ V ABC transporter (permease)
HEOGLLMH_04166 3.9e-80 yknZ V ABC transporter (permease)
HEOGLLMH_04167 6.1e-123 macB V ABC transporter, ATP-binding protein
HEOGLLMH_04168 7.5e-109 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HEOGLLMH_04169 8.1e-39 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HEOGLLMH_04170 3.7e-46 yknW S Yip1 domain
HEOGLLMH_04171 8.7e-48 yknW S Yip1 domain
HEOGLLMH_04172 1.5e-33 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HEOGLLMH_04173 3.5e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
HEOGLLMH_04174 2.4e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HEOGLLMH_04175 3.4e-94 moeA 2.10.1.1 H molybdopterin
HEOGLLMH_04176 4.4e-118 moeA 2.10.1.1 H molybdopterin
HEOGLLMH_04177 2.9e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HEOGLLMH_04178 4.8e-108 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HEOGLLMH_04179 3.4e-125 yknT
HEOGLLMH_04180 1.9e-63 rok K Repressor of ComK
HEOGLLMH_04181 2.5e-22 rok K Repressor of ComK
HEOGLLMH_04182 1.6e-79 ykuV CO thiol-disulfide
HEOGLLMH_04183 4.9e-140 ykuT M Mechanosensitive ion channel
HEOGLLMH_04184 4.8e-38 ykuS S Belongs to the UPF0180 family
HEOGLLMH_04185 5.3e-217 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HEOGLLMH_04186 8.8e-77 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HEOGLLMH_04187 9.3e-80 fld C Flavodoxin
HEOGLLMH_04188 2.7e-171 ykuO
HEOGLLMH_04189 2.5e-26 fld C Flavodoxin
HEOGLLMH_04190 4.6e-168 ccpC K Transcriptional regulator
HEOGLLMH_04191 1e-75 ykuL S CBS domain
HEOGLLMH_04192 2.5e-26 ykzF S Antirepressor AbbA
HEOGLLMH_04193 1.9e-92 ykuK S Ribonuclease H-like
HEOGLLMH_04194 3.9e-37 ykuJ S protein conserved in bacteria
HEOGLLMH_04195 1.3e-50 ykuI T Diguanylate phosphodiesterase
HEOGLLMH_04196 6.2e-89 ykuI T Diguanylate phosphodiesterase
HEOGLLMH_04197 9.9e-40 ykuI T Diguanylate phosphodiesterase
HEOGLLMH_04199 1.7e-43 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEOGLLMH_04200 1.8e-44 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEOGLLMH_04201 2.7e-18 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEOGLLMH_04202 1.5e-155 ykuE S Metallophosphoesterase
HEOGLLMH_04203 3.2e-89 ykuD S protein conserved in bacteria
HEOGLLMH_04204 7.8e-241 ykuC EGP Major facilitator Superfamily
HEOGLLMH_04205 1.4e-83 ykyB S YkyB-like protein
HEOGLLMH_04206 5.3e-167 cheV 2.7.13.3 T Chemotaxis protein CheV
HEOGLLMH_04207 2.3e-09
HEOGLLMH_04208 2.7e-36 patA 2.6.1.1 E Aminotransferase
HEOGLLMH_04209 2.8e-168 patA 2.6.1.1 E Aminotransferase
HEOGLLMH_04210 2e-30 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
HEOGLLMH_04211 7.6e-254 pilS 2.7.13.3 T PAS fold
HEOGLLMH_04212 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
HEOGLLMH_04213 4e-115 ykwD J protein with SCP PR1 domains
HEOGLLMH_04214 8.6e-50
HEOGLLMH_04215 4.3e-158 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HEOGLLMH_04216 8.2e-266 mcpC NT chemotaxis protein
HEOGLLMH_04217 1.9e-189 splB 4.1.99.14 L Spore photoproduct lyase
HEOGLLMH_04218 5.1e-37 splA S Transcriptional regulator
HEOGLLMH_04219 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HEOGLLMH_04220 2.1e-39 ptsH G phosphocarrier protein HPr
HEOGLLMH_04221 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HEOGLLMH_04222 5.1e-156 glcT K antiterminator
HEOGLLMH_04223 5.1e-176 ykvZ 5.1.1.1 K Transcriptional regulator
HEOGLLMH_04225 4.8e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HEOGLLMH_04226 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HEOGLLMH_04227 2.7e-88 stoA CO thiol-disulfide
HEOGLLMH_04228 3.1e-240 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEOGLLMH_04229 8.6e-106 ykvT 3.5.1.28 M Cell Wall Hydrolase
HEOGLLMH_04230 6e-28
HEOGLLMH_04231 7.8e-25 ykvS S protein conserved in bacteria
HEOGLLMH_04232 2.2e-41 ykvR S Protein of unknown function (DUF3219)
HEOGLLMH_04233 1.6e-31 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HEOGLLMH_04234 3.1e-133 IQ Enoyl-(Acyl carrier protein) reductase
HEOGLLMH_04235 7.5e-58 ykvN K Transcriptional regulator
HEOGLLMH_04237 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HEOGLLMH_04238 5.4e-138 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HEOGLLMH_04239 6.3e-81 queD 4.1.2.50, 4.2.3.12 H synthase
HEOGLLMH_04240 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HEOGLLMH_04241 2.5e-190
HEOGLLMH_04242 4.1e-184 ykvI S membrane
HEOGLLMH_04243 0.0 clpE O Belongs to the ClpA ClpB family
HEOGLLMH_04244 1.1e-136 motA N flagellar motor
HEOGLLMH_04245 2.2e-45 motB N Flagellar motor protein
HEOGLLMH_04246 4.2e-46 motB N Flagellar motor protein
HEOGLLMH_04247 1.5e-77 ykvE K transcriptional
HEOGLLMH_04248 4.3e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
HEOGLLMH_04249 3.4e-10 S Spo0E like sporulation regulatory protein
HEOGLLMH_04250 3.8e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HEOGLLMH_04251 6.5e-116 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HEOGLLMH_04252 3.7e-136 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HEOGLLMH_04253 6.1e-227 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HEOGLLMH_04254 2.2e-229 mtnE 2.6.1.83 E Aminotransferase
HEOGLLMH_04255 1.1e-149 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HEOGLLMH_04256 1.5e-225 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HEOGLLMH_04257 1.7e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HEOGLLMH_04259 3.9e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HEOGLLMH_04260 0.0 kinE 2.7.13.3 T Histidine kinase
HEOGLLMH_04261 2e-191 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
HEOGLLMH_04262 7.9e-24 ykzE
HEOGLLMH_04263 3.8e-114 ydfR S Protein of unknown function (DUF421)
HEOGLLMH_04264 1.3e-241 ktrB P COG0168 Trk-type K transport systems, membrane components
HEOGLLMH_04265 4.1e-156 htpX O Belongs to the peptidase M48B family
HEOGLLMH_04266 7.8e-126 ykrK S Domain of unknown function (DUF1836)
HEOGLLMH_04267 2.5e-26 sspD S small acid-soluble spore protein
HEOGLLMH_04268 3.1e-119 rsgI S Anti-sigma factor N-terminus
HEOGLLMH_04269 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEOGLLMH_04270 6e-135 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HEOGLLMH_04271 9.2e-101 ykoX S membrane-associated protein
HEOGLLMH_04272 1.4e-153 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HEOGLLMH_04273 5.4e-150 ligD 6.5.1.1 L ATP-dependent DNA ligase
HEOGLLMH_04274 3.1e-51 ligD 6.5.1.1 L ATP-dependent DNA ligase
HEOGLLMH_04275 1.5e-68 ligD 6.5.1.1 L ATP-dependent DNA ligase
HEOGLLMH_04276 2.9e-66 ykoP G polysaccharide deacetylase
HEOGLLMH_04277 2.6e-22 ykoP G polysaccharide deacetylase
HEOGLLMH_04278 1.1e-80 ykoM K transcriptional
HEOGLLMH_04279 3.1e-26 ykoL
HEOGLLMH_04280 1.9e-16
HEOGLLMH_04281 5.4e-53 tnrA K transcriptional
HEOGLLMH_04282 2.2e-238 mgtE P Acts as a magnesium transporter
HEOGLLMH_04284 3.9e-245 ydhD M Glycosyl hydrolase
HEOGLLMH_04285 3.8e-97 ykoE S ABC-type cobalt transport system, permease component
HEOGLLMH_04286 5.5e-308 P ABC transporter, ATP-binding protein
HEOGLLMH_04287 3e-131 ykoC P Cobalt transport protein
HEOGLLMH_04288 3.5e-149 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HEOGLLMH_04289 1.2e-177 isp O Belongs to the peptidase S8 family
HEOGLLMH_04290 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HEOGLLMH_04291 1.1e-119 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HEOGLLMH_04292 1.9e-217 hcaT 1.5.1.2 EGP Major facilitator Superfamily
HEOGLLMH_04293 1.1e-123 3.2.1.4 GH5,GH9 K Collagen triple helix repeat
HEOGLLMH_04294 4.5e-216 M Glycosyl transferase family 2
HEOGLLMH_04296 2.3e-59 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HEOGLLMH_04297 4.2e-71 ohrB O Organic hydroperoxide resistance protein
HEOGLLMH_04298 6.1e-88 ohrR K COG1846 Transcriptional regulators
HEOGLLMH_04299 4.8e-70 ohrA O Organic hydroperoxide resistance protein
HEOGLLMH_04300 8.1e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HEOGLLMH_04301 1.6e-205 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HEOGLLMH_04302 7.8e-171 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HEOGLLMH_04303 3.4e-49 ykkD P Multidrug resistance protein
HEOGLLMH_04304 9.4e-53 ykkC P Multidrug resistance protein
HEOGLLMH_04305 5.1e-101 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HEOGLLMH_04306 1.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
HEOGLLMH_04307 1.2e-160 ykgA E Amidinotransferase
HEOGLLMH_04308 3.9e-206 pgl 3.1.1.31 G 6-phosphogluconolactonase
HEOGLLMH_04309 1.4e-181 ykfD E Belongs to the ABC transporter superfamily
HEOGLLMH_04310 9.1e-101 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HEOGLLMH_04311 5.8e-62 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HEOGLLMH_04312 5.3e-113 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HEOGLLMH_04313 2.4e-75 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HEOGLLMH_04314 1.7e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HEOGLLMH_04315 0.0 dppE E ABC transporter substrate-binding protein
HEOGLLMH_04316 7.7e-191 dppD P Belongs to the ABC transporter superfamily
HEOGLLMH_04317 5e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEOGLLMH_04318 6.4e-160 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEOGLLMH_04319 6.5e-156 dppA E D-aminopeptidase
HEOGLLMH_04321 1.6e-285 yubD P Major Facilitator Superfamily
HEOGLLMH_04322 3.3e-205 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEOGLLMH_04324 2.9e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HEOGLLMH_04325 1.2e-195 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HEOGLLMH_04326 3.6e-106 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HEOGLLMH_04327 4.8e-179 mhqA E COG0346 Lactoylglutathione lyase and related lyases
HEOGLLMH_04328 3.8e-243 steT E amino acid
HEOGLLMH_04329 1.4e-108 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
HEOGLLMH_04330 2e-175 pit P phosphate transporter
HEOGLLMH_04331 4.1e-37 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
HEOGLLMH_04332 1.1e-86 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
HEOGLLMH_04333 8.7e-23 spoIISB S Stage II sporulation protein SB
HEOGLLMH_04334 2.4e-169 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HEOGLLMH_04335 1.3e-38 xhlB S SPP1 phage holin
HEOGLLMH_04336 1.5e-37 xhlA S Haemolysin XhlA
HEOGLLMH_04337 3.9e-139 xepA
HEOGLLMH_04338 6.5e-30 xkdX
HEOGLLMH_04340 5.6e-38
HEOGLLMH_04341 1.4e-64
HEOGLLMH_04342 1.2e-26
HEOGLLMH_04343 5e-86 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HEOGLLMH_04344 6.7e-166 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HEOGLLMH_04345 9.4e-58 xkdS S Protein of unknown function (DUF2634)
HEOGLLMH_04346 7.2e-32 xkdR S Protein of unknown function (DUF2577)
HEOGLLMH_04347 3.2e-162 xkdQ 3.2.1.96 G NLP P60 protein
HEOGLLMH_04348 6.6e-111 xkdP S Lysin motif
HEOGLLMH_04349 2.8e-150 xkdO L Transglycosylase SLT domain
HEOGLLMH_04350 5.1e-74 xkdO L Transglycosylase SLT domain
HEOGLLMH_04351 3.4e-19
HEOGLLMH_04352 6.8e-66 S Phage XkdN-like tail assembly chaperone protein, TAC
HEOGLLMH_04353 3.1e-50 xkdM S Phage tail tube protein
HEOGLLMH_04354 3.2e-11 xkdM S Phage tail tube protein
HEOGLLMH_04355 6.5e-225 xkdK S Phage tail sheath C-terminal domain
HEOGLLMH_04356 1.2e-55 xkdJ
HEOGLLMH_04357 4.1e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
HEOGLLMH_04358 7.1e-43 yqbH S Domain of unknown function (DUF3599)
HEOGLLMH_04359 1.7e-45 yqbG S Protein of unknown function (DUF3199)
HEOGLLMH_04360 1e-157 xkdG S Phage capsid family
HEOGLLMH_04361 2.6e-91 xkdF 2.1.1.72 L Putative phage serine protease XkdF
HEOGLLMH_04362 7.9e-242 yqbA S portal protein
HEOGLLMH_04363 2.3e-208 xtmB S phage terminase, large subunit
HEOGLLMH_04364 1.5e-109 xtmA L phage terminase small subunit
HEOGLLMH_04365 4.9e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HEOGLLMH_04366 2e-10 yqaO S Phage-like element PBSX protein XtrA
HEOGLLMH_04369 1.8e-121 xkdC L Bacterial dnaA protein
HEOGLLMH_04370 6.8e-113 xkdB K sequence-specific DNA binding
HEOGLLMH_04372 5.3e-52 xre K Helix-turn-helix XRE-family like proteins
HEOGLLMH_04373 7.8e-111 xkdA E IrrE N-terminal-like domain
HEOGLLMH_04374 7.2e-112 yjqB S phage-related replication protein
HEOGLLMH_04375 2.2e-51 yjqA S Bacterial PH domain
HEOGLLMH_04376 1.9e-73 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HEOGLLMH_04377 5e-65 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HEOGLLMH_04379 4.9e-215 S response regulator aspartate phosphatase
HEOGLLMH_04380 6.2e-79 yjoA S DinB family
HEOGLLMH_04381 3.9e-131 MA20_18170 S membrane transporter protein
HEOGLLMH_04382 3.4e-134 salB V Domain of unknown function (DUF4135)
HEOGLLMH_04383 1.4e-37 salB V Domain of unknown function (DUF4135)
HEOGLLMH_04386 2.1e-214 lanT 3.6.3.27 V Peptidase C39 family
HEOGLLMH_04387 2.1e-292 lcnDR2 V Lanthionine synthetase C-like protein
HEOGLLMH_04389 9.2e-60 K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEOGLLMH_04390 3.4e-47 narQ 2.7.13.3 T Histidine kinase
HEOGLLMH_04392 1.3e-66 S ABC-2 family transporter protein
HEOGLLMH_04393 1.8e-106 V ABC transporter, ATP-binding protein
HEOGLLMH_04394 1.6e-130 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HEOGLLMH_04395 1e-87 T Transcriptional regulatory protein, C terminal
HEOGLLMH_04396 2e-288 uxaA 4.2.1.7, 4.4.1.24 G Altronate
HEOGLLMH_04397 3.4e-285 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
HEOGLLMH_04398 3.4e-183 exuR K transcriptional
HEOGLLMH_04399 7.3e-253 yjmB G symporter YjmB
HEOGLLMH_04400 5.1e-278 uxaC 5.3.1.12 G glucuronate isomerase
HEOGLLMH_04401 1.3e-218 yjlD 1.6.99.3 C NADH dehydrogenase
HEOGLLMH_04402 7e-66 yjlC S Protein of unknown function (DUF1641)
HEOGLLMH_04403 5.2e-92 yjlB S Cupin domain
HEOGLLMH_04404 2.7e-177 yjlA EG Putative multidrug resistance efflux transporter
HEOGLLMH_04405 6.4e-131 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
HEOGLLMH_04406 4.6e-124 ybbM S transport system, permease component
HEOGLLMH_04407 5.1e-145 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HEOGLLMH_04408 6.8e-29
HEOGLLMH_04409 1.5e-222 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HEOGLLMH_04410 6.9e-184 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
HEOGLLMH_04411 3.3e-27 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
HEOGLLMH_04412 1.1e-90 yjgD S Protein of unknown function (DUF1641)
HEOGLLMH_04413 1.4e-228 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
HEOGLLMH_04414 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
HEOGLLMH_04415 1.8e-101 yjgB S Domain of unknown function (DUF4309)
HEOGLLMH_04416 1.7e-69 T PhoQ Sensor
HEOGLLMH_04417 8.3e-21 yjfB S Putative motility protein
HEOGLLMH_04419 1.5e-104 yhiD S MgtC SapB transporter
HEOGLLMH_04421 1.7e-144 N Kelch motif
HEOGLLMH_04422 2.4e-124 5.4.2.6 S Haloacid dehalogenase-like hydrolase
HEOGLLMH_04423 3.6e-130 lacR K COG1349 Transcriptional regulators of sugar metabolism
HEOGLLMH_04424 6.9e-283 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
HEOGLLMH_04425 9.1e-50 lacF 2.7.1.207 G phosphotransferase system
HEOGLLMH_04426 5.1e-290 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEOGLLMH_04427 8.2e-45 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HEOGLLMH_04428 2.2e-154 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HEOGLLMH_04429 2.2e-190 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HEOGLLMH_04430 1.2e-230 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HEOGLLMH_04431 2.1e-45 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HEOGLLMH_04432 1.6e-218 ganA 3.2.1.89 G arabinogalactan
HEOGLLMH_04433 1.5e-80 napB K helix_turn_helix multiple antibiotic resistance protein
HEOGLLMH_04434 6.3e-252 yfjF EGP Belongs to the major facilitator superfamily
HEOGLLMH_04435 8.4e-47 yjcS S Antibiotic biosynthesis monooxygenase
HEOGLLMH_04436 8.2e-168 bla 3.5.2.6 V beta-lactamase
HEOGLLMH_04438 6.5e-74 yobL S Bacterial EndoU nuclease
HEOGLLMH_04439 6.7e-11 yobL L Belongs to the WXG100 family
HEOGLLMH_04440 1.2e-75 yobL L Belongs to the WXG100 family
HEOGLLMH_04441 1.1e-37 yobL S Bacterial EndoU nuclease
HEOGLLMH_04442 8.2e-57
HEOGLLMH_04445 1.3e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HEOGLLMH_04446 2.3e-212 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HEOGLLMH_04447 1.8e-125 yjcH P COG2382 Enterochelin esterase and related enzymes
HEOGLLMH_04448 1.6e-91 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
HEOGLLMH_04449 2.5e-74 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEOGLLMH_04450 9.4e-36 K SpoVT / AbrB like domain
HEOGLLMH_04451 9.7e-39 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
HEOGLLMH_04452 2.9e-63 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
HEOGLLMH_04453 3e-125 S ABC-2 type transporter
HEOGLLMH_04454 1.6e-134 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
HEOGLLMH_04455 2.1e-36
HEOGLLMH_04456 0.0 yjcD 3.6.4.12 L DNA helicase
HEOGLLMH_04457 3.8e-38 spoVIF S Stage VI sporulation protein F
HEOGLLMH_04461 2.1e-55 yjcA S Protein of unknown function (DUF1360)
HEOGLLMH_04462 3.2e-57 cotV S Spore Coat Protein X and V domain
HEOGLLMH_04463 1.1e-23 cotW
HEOGLLMH_04464 1.5e-75 cotX S Spore Coat Protein X and V domain
HEOGLLMH_04465 9.2e-94 cotY S Spore coat protein Z
HEOGLLMH_04466 1e-83 cotZ S Spore coat protein
HEOGLLMH_04467 1.4e-59 yjbX S Spore coat protein
HEOGLLMH_04468 4e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HEOGLLMH_04469 2.9e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HEOGLLMH_04470 8.4e-190 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HEOGLLMH_04471 2.6e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HEOGLLMH_04472 4.7e-16 thiS H Thiamine biosynthesis
HEOGLLMH_04473 3.1e-77 thiO 1.4.3.19 E Glycine oxidase
HEOGLLMH_04474 6e-120 thiO 1.4.3.19 E Glycine oxidase
HEOGLLMH_04475 4.2e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
HEOGLLMH_04476 2.1e-16 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HEOGLLMH_04477 1.1e-88 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HEOGLLMH_04478 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HEOGLLMH_04479 3e-144 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HEOGLLMH_04480 6.3e-165 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HEOGLLMH_04481 1.3e-79 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HEOGLLMH_04482 1.1e-107 yjbM 2.7.6.5 S GTP pyrophosphokinase
HEOGLLMH_04483 6e-61 yjbL S Belongs to the UPF0738 family
HEOGLLMH_04484 6.7e-19 yjbK S protein conserved in bacteria
HEOGLLMH_04485 3.2e-118 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HEOGLLMH_04486 4.8e-72 yjbI S Bacterial-like globin
HEOGLLMH_04487 7e-102 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HEOGLLMH_04488 5.8e-19
HEOGLLMH_04489 0.0 pepF E oligoendopeptidase F
HEOGLLMH_04490 4.9e-27 yjbF S Competence protein
HEOGLLMH_04491 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HEOGLLMH_04492 8.1e-109 yjbE P Integral membrane protein TerC family
HEOGLLMH_04493 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HEOGLLMH_04494 2e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEOGLLMH_04495 4.4e-123 S Putative glycosyl hydrolase domain
HEOGLLMH_04496 1.1e-68 S Putative glycosyl hydrolase domain
HEOGLLMH_04497 1.8e-170 oppF E Belongs to the ABC transporter superfamily
HEOGLLMH_04498 2.7e-202 oppD P Belongs to the ABC transporter superfamily
HEOGLLMH_04499 1.3e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEOGLLMH_04500 9.2e-167 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEOGLLMH_04501 3.1e-141 oppA E ABC transporter substrate-binding protein
HEOGLLMH_04502 2.7e-166 oppA E ABC transporter substrate-binding protein
HEOGLLMH_04503 4e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HEOGLLMH_04504 5.5e-146 yjbA S Belongs to the UPF0736 family
HEOGLLMH_04505 1e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEOGLLMH_04506 2.2e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEOGLLMH_04507 9.2e-135 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
HEOGLLMH_04508 6.8e-85 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
HEOGLLMH_04509 9.6e-129 appF E Belongs to the ABC transporter superfamily
HEOGLLMH_04510 1e-36 appF E Belongs to the ABC transporter superfamily
HEOGLLMH_04511 9.7e-183 appD P Belongs to the ABC transporter superfamily
HEOGLLMH_04512 2.1e-148 yjaZ O Zn-dependent protease
HEOGLLMH_04513 1.1e-192 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HEOGLLMH_04514 8.8e-29 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HEOGLLMH_04515 3.3e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HEOGLLMH_04516 5.9e-32 yjzB
HEOGLLMH_04517 1.1e-26 comZ S ComZ
HEOGLLMH_04518 1.9e-166 med S Transcriptional activator protein med
HEOGLLMH_04519 1e-104 yjaV
HEOGLLMH_04520 1.1e-138 yjaU I carboxylic ester hydrolase activity
HEOGLLMH_04521 1.5e-23 yjzD S Protein of unknown function (DUF2929)
HEOGLLMH_04522 1.2e-27 yjzC S YjzC-like protein
HEOGLLMH_04523 2.1e-177 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HEOGLLMH_04524 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
HEOGLLMH_04525 1.2e-202 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HEOGLLMH_04526 9.9e-219 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HEOGLLMH_04527 4.9e-137 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
HEOGLLMH_04528 4.5e-208 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HEOGLLMH_04529 6.2e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HEOGLLMH_04530 9.1e-90 norB G Major Facilitator Superfamily
HEOGLLMH_04531 1.8e-195 yitY C D-arabinono-1,4-lactone oxidase
HEOGLLMH_04532 1.1e-49 yitY C D-arabinono-1,4-lactone oxidase
HEOGLLMH_04533 1.8e-80 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HEOGLLMH_04534 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
HEOGLLMH_04535 1.1e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HEOGLLMH_04536 6e-154 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HEOGLLMH_04537 3.5e-07
HEOGLLMH_04538 4.4e-26 S Protein of unknown function (DUF3813)
HEOGLLMH_04539 2.9e-81 ipi S Intracellular proteinase inhibitor
HEOGLLMH_04540 3.9e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
HEOGLLMH_04541 1.4e-158 yitS S protein conserved in bacteria
HEOGLLMH_04543 1.3e-245 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
HEOGLLMH_04544 1.8e-237 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
HEOGLLMH_04545 3.9e-162 yufN S ABC transporter substrate-binding protein PnrA-like
HEOGLLMH_04546 2.6e-160 cvfB S protein conserved in bacteria

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)