ORF_ID e_value Gene_name EC_number CAZy COGs Description
ALFGKDHI_00001 1.5e-255 S LPXTG-motif cell wall anchor domain protein
ALFGKDHI_00002 2.2e-58 S LPXTG-motif cell wall anchor domain protein
ALFGKDHI_00003 3.2e-223 S LPXTG-motif cell wall anchor domain protein
ALFGKDHI_00004 3.9e-196 S LPXTG-motif cell wall anchor domain protein
ALFGKDHI_00005 5e-99 L Helix-turn-helix domain
ALFGKDHI_00006 4.8e-210 ugpC E Belongs to the ABC transporter superfamily
ALFGKDHI_00007 5.8e-174 K Psort location Cytoplasmic, score
ALFGKDHI_00008 0.0 KLT Protein tyrosine kinase
ALFGKDHI_00009 8.4e-151 O Thioredoxin
ALFGKDHI_00011 2.7e-211 S G5
ALFGKDHI_00012 6.3e-171 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
ALFGKDHI_00013 1.2e-167 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ALFGKDHI_00014 6.7e-113 S LytR cell envelope-related transcriptional attenuator
ALFGKDHI_00015 2.8e-279 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
ALFGKDHI_00016 5.2e-124 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
ALFGKDHI_00017 0.0 M Conserved repeat domain
ALFGKDHI_00018 0.0 murJ KLT MviN-like protein
ALFGKDHI_00019 9e-204 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
ALFGKDHI_00020 2.7e-244 parB K Belongs to the ParB family
ALFGKDHI_00021 8.5e-179 parA D CobQ CobB MinD ParA nucleotide binding domain protein
ALFGKDHI_00022 1.5e-124 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
ALFGKDHI_00023 1.5e-92 jag S Putative single-stranded nucleic acids-binding domain
ALFGKDHI_00024 2.3e-171 yidC U Membrane protein insertase, YidC Oxa1 family
ALFGKDHI_00025 4.5e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
ALFGKDHI_00026 1.3e-298 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ALFGKDHI_00027 6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
ALFGKDHI_00028 7.2e-231 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ALFGKDHI_00029 1.4e-88 S Protein of unknown function (DUF721)
ALFGKDHI_00030 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ALFGKDHI_00031 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ALFGKDHI_00032 4.6e-73 S Transmembrane domain of unknown function (DUF3566)
ALFGKDHI_00033 3.2e-15 abfA1 3.2.1.55 GH51 G arabinose metabolic process
ALFGKDHI_00035 3.5e-187 G Glycosyl hydrolases family 43
ALFGKDHI_00036 1.8e-186 K Periplasmic binding protein domain
ALFGKDHI_00037 6.8e-228 I Serine aminopeptidase, S33
ALFGKDHI_00038 1.7e-08 K helix_turn _helix lactose operon repressor
ALFGKDHI_00039 9.6e-42 S Protein of unknown function (DUF2442)
ALFGKDHI_00040 3.4e-18 S Domain of unknown function (DUF4160)
ALFGKDHI_00043 1.9e-24 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
ALFGKDHI_00044 2.3e-259 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
ALFGKDHI_00045 2.5e-124 gntR K FCD
ALFGKDHI_00046 2.5e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
ALFGKDHI_00047 0.0 3.2.1.55 GH51 G arabinose metabolic process
ALFGKDHI_00050 0.0 G Glycosyl hydrolase family 20, domain 2
ALFGKDHI_00051 3.3e-189 K helix_turn _helix lactose operon repressor
ALFGKDHI_00052 2.5e-77 ulaC 2.7.1.194, 2.7.1.197, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
ALFGKDHI_00053 3.3e-40 ulaC 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
ALFGKDHI_00054 1.6e-261 ulaA 2.7.1.194 S PTS system sugar-specific permease component
ALFGKDHI_00055 2.3e-136 S Protein of unknown function DUF45
ALFGKDHI_00056 1.9e-83 dps P Belongs to the Dps family
ALFGKDHI_00057 1.3e-188 yddG EG EamA-like transporter family
ALFGKDHI_00058 1.2e-241 ytfL P Transporter associated domain
ALFGKDHI_00059 1.9e-95 K helix_turn _helix lactose operon repressor
ALFGKDHI_00060 6.9e-119 cah 4.2.1.1 P Reversible hydration of carbon dioxide
ALFGKDHI_00061 2.9e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
ALFGKDHI_00062 0.0 trxB1 1.8.1.9 C Thioredoxin domain
ALFGKDHI_00063 6.5e-309 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
ALFGKDHI_00064 7.3e-239 yhjX EGP Major facilitator Superfamily
ALFGKDHI_00065 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ALFGKDHI_00066 0.0 yjjP S Threonine/Serine exporter, ThrE
ALFGKDHI_00067 1.1e-155 S Amidohydrolase family
ALFGKDHI_00068 5.2e-17 S Amidohydrolase family
ALFGKDHI_00069 1.8e-195 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
ALFGKDHI_00070 6.5e-204 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
ALFGKDHI_00071 6.2e-45 S Protein of unknown function (DUF3073)
ALFGKDHI_00072 1.8e-87 K LytTr DNA-binding domain
ALFGKDHI_00073 2.5e-13 T protein histidine kinase activity
ALFGKDHI_00074 4.8e-76 T protein histidine kinase activity
ALFGKDHI_00075 1.2e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
ALFGKDHI_00076 3e-28 I transferase activity, transferring acyl groups other than amino-acyl groups
ALFGKDHI_00077 0.0 lytC 2.1.1.197, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
ALFGKDHI_00078 1.4e-44 rfbJ M Glycosyl transferase family 2
ALFGKDHI_00079 8.9e-116 rfbJ M Glycosyl transferase family 2
ALFGKDHI_00080 0.0
ALFGKDHI_00081 2.1e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
ALFGKDHI_00082 0.0 3.6.4.12 K Putative DNA-binding domain
ALFGKDHI_00083 1.3e-289 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
ALFGKDHI_00084 1.6e-42 L Transposase DDE domain
ALFGKDHI_00085 1.7e-16 L Transposase
ALFGKDHI_00086 1.1e-139 L HTH-like domain
ALFGKDHI_00087 9.4e-155 L Transposase, Mutator family
ALFGKDHI_00088 1.2e-168 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ALFGKDHI_00089 8.7e-131 rgpC U Transport permease protein
ALFGKDHI_00090 1.3e-208 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
ALFGKDHI_00091 2.5e-294 S Tetratricopeptide repeat
ALFGKDHI_00092 0.0 rgpF M Rhamnan synthesis protein F
ALFGKDHI_00093 4.9e-193 M Glycosyltransferase like family 2
ALFGKDHI_00094 7.9e-199 L Transposase and inactivated derivatives IS30 family
ALFGKDHI_00095 4.4e-258 S Domain of unknown function (DUF4143)
ALFGKDHI_00096 1.7e-16 yccF S Inner membrane component domain
ALFGKDHI_00097 4.5e-12
ALFGKDHI_00098 0.0 cysB 4.2.1.22 EGP Major facilitator Superfamily
ALFGKDHI_00099 3.6e-41 tnp7109-21 L Integrase core domain
ALFGKDHI_00100 6.9e-44 L IstB-like ATP binding protein
ALFGKDHI_00101 1.4e-43 L Transposase
ALFGKDHI_00102 1.3e-38 V ATPases associated with a variety of cellular activities
ALFGKDHI_00103 2e-73 I Sterol carrier protein
ALFGKDHI_00104 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
ALFGKDHI_00105 3.4e-35
ALFGKDHI_00106 6.4e-145 gluP 3.4.21.105 S Rhomboid family
ALFGKDHI_00107 3e-256 L ribosomal rna small subunit methyltransferase
ALFGKDHI_00108 2.6e-71 crgA D Involved in cell division
ALFGKDHI_00109 3.5e-143 S Bacterial protein of unknown function (DUF881)
ALFGKDHI_00110 4.8e-232 srtA 3.4.22.70 M Sortase family
ALFGKDHI_00111 3.4e-120 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
ALFGKDHI_00112 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
ALFGKDHI_00113 2e-183 T Protein tyrosine kinase
ALFGKDHI_00114 2.8e-263 pbpA M penicillin-binding protein
ALFGKDHI_00115 2.8e-266 rodA D Belongs to the SEDS family
ALFGKDHI_00116 2.8e-259 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
ALFGKDHI_00117 7.9e-94 fhaB T Inner membrane component of T3SS, cytoplasmic domain
ALFGKDHI_00118 1e-130 fhaA T Protein of unknown function (DUF2662)
ALFGKDHI_00119 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
ALFGKDHI_00120 0.0 pip S YhgE Pip domain protein
ALFGKDHI_00121 5.3e-296 pip S YhgE Pip domain protein
ALFGKDHI_00122 1.9e-205 pldB 3.1.1.5 I Serine aminopeptidase, S33
ALFGKDHI_00123 2.5e-162 yicL EG EamA-like transporter family
ALFGKDHI_00124 2.6e-103
ALFGKDHI_00126 5.4e-197 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ALFGKDHI_00128 1.4e-26 KL Domain of unknown function (DUF3427)
ALFGKDHI_00129 0.0 KL Domain of unknown function (DUF3427)
ALFGKDHI_00130 1.7e-90 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
ALFGKDHI_00131 5.2e-39 D DivIVA domain protein
ALFGKDHI_00132 9.3e-53 ybjQ S Putative heavy-metal-binding
ALFGKDHI_00133 7.6e-157 I Serine aminopeptidase, S33
ALFGKDHI_00134 5.9e-85 yjcF Q Acetyltransferase (GNAT) domain
ALFGKDHI_00136 3.2e-258 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
ALFGKDHI_00137 6.5e-244 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
ALFGKDHI_00138 0.0 cadA P E1-E2 ATPase
ALFGKDHI_00139 5e-273 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
ALFGKDHI_00140 3.1e-170 htpX O Belongs to the peptidase M48B family
ALFGKDHI_00142 1.9e-62 S Protein of unknown function DUF262
ALFGKDHI_00143 1.7e-84 S Protein of unknown function DUF262
ALFGKDHI_00144 4.7e-196
ALFGKDHI_00145 2.1e-80 S Nucleotidyltransferase domain
ALFGKDHI_00146 5.2e-69 K FR47-like protein
ALFGKDHI_00147 5.7e-41 S Polyketide cyclase / dehydrase and lipid transport
ALFGKDHI_00148 1.2e-83 S GyrI-like small molecule binding domain
ALFGKDHI_00149 3.1e-33 S Bacterial mobilisation protein (MobC)
ALFGKDHI_00150 3.9e-116 ltrBE1 U Relaxase/Mobilisation nuclease domain
ALFGKDHI_00151 5.8e-48
ALFGKDHI_00152 5.6e-247 3.5.1.104 G Polysaccharide deacetylase
ALFGKDHI_00153 1.2e-199 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
ALFGKDHI_00154 3e-68 D AAA domain, putative AbiEii toxin, Type IV TA system
ALFGKDHI_00155 3.9e-10 V TIGR02646 family
ALFGKDHI_00156 1.9e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ALFGKDHI_00157 2.2e-163 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ALFGKDHI_00158 1.5e-59 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ALFGKDHI_00159 8.4e-193 K helix_turn _helix lactose operon repressor
ALFGKDHI_00160 4.8e-78 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
ALFGKDHI_00161 1.6e-297 scrT G Transporter major facilitator family protein
ALFGKDHI_00162 5e-254 yhjE EGP Sugar (and other) transporter
ALFGKDHI_00163 2.8e-204 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ALFGKDHI_00164 8.2e-204 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ALFGKDHI_00165 8.8e-184 gmk 1.1.1.23, 2.7.4.8 S Protein of unknown function (DUF559)
ALFGKDHI_00166 0.0 lacZ 3.2.1.23 G Psort location Cytoplasmic, score 8.87
ALFGKDHI_00167 3.5e-277 aroP E aromatic amino acid transport protein AroP K03293
ALFGKDHI_00168 7e-101 K Transcriptional regulator C-terminal region
ALFGKDHI_00169 2.6e-129 V ABC transporter
ALFGKDHI_00170 0.0 V FtsX-like permease family
ALFGKDHI_00171 8.6e-84 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ALFGKDHI_00172 3e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ALFGKDHI_00173 9.9e-39 E ABC transporter
ALFGKDHI_00174 2.9e-99 bcp 1.11.1.15 O Redoxin
ALFGKDHI_00175 1.3e-150 S Virulence factor BrkB
ALFGKDHI_00176 4.8e-48
ALFGKDHI_00178 8.1e-99 L Restriction endonuclease NotI
ALFGKDHI_00179 9.1e-82
ALFGKDHI_00180 3.3e-24 L Transposase, Mutator family
ALFGKDHI_00181 4.7e-137 L IstB-like ATP binding protein
ALFGKDHI_00182 1.3e-245 L Transposase
ALFGKDHI_00183 1.3e-77 S CRISPR-associated protein (Cas_Csn2)
ALFGKDHI_00184 7.5e-126 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ALFGKDHI_00185 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
ALFGKDHI_00187 3.9e-16 M Belongs to the glycosyl hydrolase 30 family
ALFGKDHI_00188 2.1e-93 M Belongs to the glycosyl hydrolase 30 family
ALFGKDHI_00189 2.2e-190 1.1.1.65 C Aldo/keto reductase family
ALFGKDHI_00190 1.2e-42 S Protein of unknown function (DUF1778)
ALFGKDHI_00191 2.9e-93 ydgJ K helix_turn_helix multiple antibiotic resistance protein
ALFGKDHI_00192 0.0 lmrA1 V ABC transporter, ATP-binding protein
ALFGKDHI_00193 0.0 lmrA2 V ABC transporter transmembrane region
ALFGKDHI_00194 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
ALFGKDHI_00195 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
ALFGKDHI_00196 1.2e-38
ALFGKDHI_00197 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ALFGKDHI_00198 7.8e-224 S Peptidase dimerisation domain
ALFGKDHI_00199 1.3e-91 P ABC-type metal ion transport system permease component
ALFGKDHI_00200 1.4e-166 S Sucrose-6F-phosphate phosphohydrolase
ALFGKDHI_00201 5.4e-103 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ALFGKDHI_00202 1.1e-49 relB L RelB antitoxin
ALFGKDHI_00203 3.5e-41 T Toxic component of a toxin-antitoxin (TA) module
ALFGKDHI_00204 1.3e-207 E Belongs to the peptidase S1B family
ALFGKDHI_00205 3.1e-34
ALFGKDHI_00206 1.1e-205 S HipA-like C-terminal domain
ALFGKDHI_00207 2e-232 hsdM 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
ALFGKDHI_00208 4.6e-73 S EcsC protein family
ALFGKDHI_00210 1.6e-26 L DNA integration
ALFGKDHI_00211 1.1e-26
ALFGKDHI_00212 2.1e-140 fic D Fic/DOC family
ALFGKDHI_00213 3.6e-233 L Phage integrase family
ALFGKDHI_00214 9e-28
ALFGKDHI_00215 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ALFGKDHI_00216 2.2e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
ALFGKDHI_00217 1.4e-47 S Domain of unknown function (DUF4193)
ALFGKDHI_00218 1.4e-187 S Protein of unknown function (DUF3071)
ALFGKDHI_00219 1.3e-237 S Type I phosphodiesterase / nucleotide pyrophosphatase
ALFGKDHI_00220 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
ALFGKDHI_00221 0.0 lhr L DEAD DEAH box helicase
ALFGKDHI_00222 1.2e-36 K Transcriptional regulator
ALFGKDHI_00223 7.6e-277 aspA 4.3.1.1 E Fumarase C C-terminus
ALFGKDHI_00224 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
ALFGKDHI_00225 6.3e-181 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
ALFGKDHI_00226 1.7e-122
ALFGKDHI_00227 1.5e-200 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
ALFGKDHI_00228 0.0 pknL 2.7.11.1 KLT PASTA
ALFGKDHI_00229 5.1e-133 plsC2 2.3.1.51 I Phosphate acyltransferases
ALFGKDHI_00230 1.5e-109
ALFGKDHI_00231 7.9e-191 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ALFGKDHI_00232 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
ALFGKDHI_00233 6.7e-111 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ALFGKDHI_00234 1.3e-07
ALFGKDHI_00235 2.9e-87 recX S Modulates RecA activity
ALFGKDHI_00236 1.4e-215 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ALFGKDHI_00237 3.7e-40 S Protein of unknown function (DUF3046)
ALFGKDHI_00238 2.1e-80 K Helix-turn-helix XRE-family like proteins
ALFGKDHI_00239 1.3e-96 cinA 3.5.1.42 S Belongs to the CinA family
ALFGKDHI_00240 7.7e-123 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ALFGKDHI_00241 0.0 ftsK D FtsK SpoIIIE family protein
ALFGKDHI_00242 2e-137 fic D Fic/DOC family
ALFGKDHI_00243 3e-185 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ALFGKDHI_00244 1.3e-279 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ALFGKDHI_00245 3.2e-121 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
ALFGKDHI_00246 6.4e-171 ydeD EG EamA-like transporter family
ALFGKDHI_00247 6.6e-132 ybhL S Belongs to the BI1 family
ALFGKDHI_00248 4e-97 S Domain of unknown function (DUF5067)
ALFGKDHI_00249 1.6e-266 T Histidine kinase
ALFGKDHI_00250 1.1e-116 K helix_turn_helix, Lux Regulon
ALFGKDHI_00251 0.0 S Protein of unknown function DUF262
ALFGKDHI_00252 2e-302 gmk 2.4.2.10, 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
ALFGKDHI_00253 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
ALFGKDHI_00254 2.2e-237 carA 6.3.5.5 F Belongs to the CarA family
ALFGKDHI_00255 5e-90 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ALFGKDHI_00256 3.3e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ALFGKDHI_00258 1.5e-190 EGP Transmembrane secretion effector
ALFGKDHI_00259 0.0 S Esterase-like activity of phytase
ALFGKDHI_00260 8.1e-232 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ALFGKDHI_00261 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ALFGKDHI_00262 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
ALFGKDHI_00263 9.3e-62 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ALFGKDHI_00265 1.7e-198 ltaE 4.1.2.48 E Beta-eliminating lyase
ALFGKDHI_00266 9.2e-228 M Glycosyl transferase 4-like domain
ALFGKDHI_00267 0.0 M Parallel beta-helix repeats
ALFGKDHI_00268 2.2e-235 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ALFGKDHI_00269 8.6e-139 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
ALFGKDHI_00270 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
ALFGKDHI_00271 2e-107
ALFGKDHI_00272 2.9e-95 S Protein of unknown function (DUF4230)
ALFGKDHI_00273 6.5e-148 mug 3.2.2.28 L Uracil DNA glycosylase superfamily
ALFGKDHI_00274 1.3e-20 K DNA-binding transcription factor activity
ALFGKDHI_00275 8.9e-68 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ALFGKDHI_00276 5.9e-32
ALFGKDHI_00277 1.1e-300 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
ALFGKDHI_00278 1.3e-292 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ALFGKDHI_00279 2e-186 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
ALFGKDHI_00280 7.2e-239 purD 6.3.4.13 F Belongs to the GARS family
ALFGKDHI_00281 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
ALFGKDHI_00282 1.7e-246 S Putative esterase
ALFGKDHI_00283 0.0 lysX S Uncharacterised conserved protein (DUF2156)
ALFGKDHI_00285 3.9e-162 P Zinc-uptake complex component A periplasmic
ALFGKDHI_00286 3.7e-137 S cobalamin synthesis protein
ALFGKDHI_00287 4.4e-46 rpmB J Ribosomal L28 family
ALFGKDHI_00288 1.7e-48 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ALFGKDHI_00289 5.7e-42 rpmE2 J Ribosomal protein L31
ALFGKDHI_00290 8.2e-15 rpmJ J Ribosomal protein L36
ALFGKDHI_00291 2.3e-23 J Ribosomal L32p protein family
ALFGKDHI_00292 1.2e-200 ycgR S Predicted permease
ALFGKDHI_00293 1e-153 S TIGRFAM TIGR03943 family protein
ALFGKDHI_00294 9.8e-45
ALFGKDHI_00295 4.3e-73 zur P Belongs to the Fur family
ALFGKDHI_00296 6.2e-229 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ALFGKDHI_00297 4.7e-85 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ALFGKDHI_00298 6.5e-179 adh3 C Zinc-binding dehydrogenase
ALFGKDHI_00299 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ALFGKDHI_00301 2e-43 S Memo-like protein
ALFGKDHI_00302 6.1e-227 K Putative ATP-dependent DNA helicase recG C-terminal
ALFGKDHI_00303 1.7e-159 K Helix-turn-helix domain, rpiR family
ALFGKDHI_00304 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
ALFGKDHI_00305 2.3e-248 dgt 3.1.5.1 F Phosphohydrolase-associated domain
ALFGKDHI_00306 2e-263 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ALFGKDHI_00307 4.4e-269 yhdG E aromatic amino acid transport protein AroP K03293
ALFGKDHI_00308 7.1e-94 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ALFGKDHI_00309 2.3e-92 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
ALFGKDHI_00310 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
ALFGKDHI_00311 2e-219 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
ALFGKDHI_00312 2e-191 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
ALFGKDHI_00313 4.4e-109
ALFGKDHI_00314 1.6e-188 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ALFGKDHI_00315 1.2e-152 sapF E ATPases associated with a variety of cellular activities
ALFGKDHI_00316 9.7e-141 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
ALFGKDHI_00317 6.4e-163 EP Binding-protein-dependent transport system inner membrane component
ALFGKDHI_00318 1.4e-170 P Binding-protein-dependent transport system inner membrane component
ALFGKDHI_00319 1.6e-310 E ABC transporter, substrate-binding protein, family 5
ALFGKDHI_00320 3.6e-143 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ALFGKDHI_00321 2e-277 G Bacterial extracellular solute-binding protein
ALFGKDHI_00322 3.3e-62 G carbohydrate transport
ALFGKDHI_00323 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
ALFGKDHI_00324 3.8e-125 G ABC transporter permease
ALFGKDHI_00325 2.9e-190 K Periplasmic binding protein domain
ALFGKDHI_00326 7.7e-21 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
ALFGKDHI_00327 0.0 3.2.1.51 GH29 G Alpha-L-fucosidase
ALFGKDHI_00329 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ALFGKDHI_00330 3.8e-55 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
ALFGKDHI_00331 3.1e-278 aldH 1.2.1.3, 1.2.1.5 C Aldehyde dehydrogenase family
ALFGKDHI_00332 5e-125 XK27_08050 O prohibitin homologues
ALFGKDHI_00333 1.5e-244 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
ALFGKDHI_00334 4e-234 metC 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
ALFGKDHI_00335 2.1e-260 nox 1.6.3.4 C Pyridine nucleotide-disulphide oxidoreductase
ALFGKDHI_00336 9.9e-225 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
ALFGKDHI_00337 0.0 macB_2 V ATPases associated with a variety of cellular activities
ALFGKDHI_00338 0.0 ctpE P E1-E2 ATPase
ALFGKDHI_00339 6.4e-54 racA K MerR, DNA binding
ALFGKDHI_00340 3.2e-197 yghZ C Aldo/keto reductase family
ALFGKDHI_00341 7.4e-100 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
ALFGKDHI_00342 6e-249 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
ALFGKDHI_00343 1.1e-149 map 3.4.11.18 E Methionine aminopeptidase
ALFGKDHI_00344 8.8e-122 S Short repeat of unknown function (DUF308)
ALFGKDHI_00345 0.0 pepO 3.4.24.71 O Peptidase family M13
ALFGKDHI_00346 1.6e-120 L Single-strand binding protein family
ALFGKDHI_00347 8.8e-170
ALFGKDHI_00348 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
ALFGKDHI_00350 1.1e-269 recD2 3.6.4.12 L PIF1-like helicase
ALFGKDHI_00351 1e-159 supH S Sucrose-6F-phosphate phosphohydrolase
ALFGKDHI_00352 2e-120 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
ALFGKDHI_00353 2.7e-26 KT Transcriptional regulatory protein, C terminal
ALFGKDHI_00354 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
ALFGKDHI_00355 5.3e-289 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
ALFGKDHI_00356 8e-192 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
ALFGKDHI_00357 5.2e-116 ywlC 2.7.7.87 J Belongs to the SUA5 family
ALFGKDHI_00358 2.4e-55 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
ALFGKDHI_00359 1.2e-185 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
ALFGKDHI_00360 1.2e-189 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ALFGKDHI_00361 3.9e-36 rpmE J Binds the 23S rRNA
ALFGKDHI_00363 1.8e-195 K helix_turn_helix, arabinose operon control protein
ALFGKDHI_00364 2.6e-163 glcU G Sugar transport protein
ALFGKDHI_00365 1.2e-178 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
ALFGKDHI_00366 7.1e-258 cma 2.1.1.79 M Mycolic acid cyclopropane synthetase
ALFGKDHI_00367 3.2e-103
ALFGKDHI_00368 4.8e-129 S Metallo-beta-lactamase domain protein
ALFGKDHI_00369 1.3e-245 L Transposase
ALFGKDHI_00370 2.3e-136 L IstB-like ATP binding protein
ALFGKDHI_00371 8.3e-170 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
ALFGKDHI_00372 1.2e-141 3.5.2.6 V Beta-lactamase enzyme family
ALFGKDHI_00373 0.0 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
ALFGKDHI_00374 4.2e-164 EG EamA-like transporter family
ALFGKDHI_00376 2e-125 V FtsX-like permease family
ALFGKDHI_00377 2.9e-146 S Sulfite exporter TauE/SafE
ALFGKDHI_00379 4.4e-216 MA20_36090 S Psort location Cytoplasmic, score 8.87
ALFGKDHI_00380 3.7e-251 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
ALFGKDHI_00381 2.1e-35 1.1.1.122, 1.1.1.65 C Aldo/keto reductase family
ALFGKDHI_00382 4e-73 EGP Major facilitator superfamily
ALFGKDHI_00383 3.7e-179 glkA 2.7.1.2 G ROK family
ALFGKDHI_00384 4.1e-300 S ATPases associated with a variety of cellular activities
ALFGKDHI_00385 1.2e-55 EGP Major facilitator Superfamily
ALFGKDHI_00386 2.2e-159 I alpha/beta hydrolase fold
ALFGKDHI_00387 6.5e-116 S Pyridoxamine 5'-phosphate oxidase
ALFGKDHI_00389 1.7e-48 S DUF218 domain
ALFGKDHI_00390 4.4e-18 S Protein of unknown function (DUF979)
ALFGKDHI_00391 4.4e-115 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ALFGKDHI_00393 2.4e-306 yjjK S ATP-binding cassette protein, ChvD family
ALFGKDHI_00394 0.0 3.2.1.52, 3.2.1.83 GH16,GH20 G hydrolase family 20, catalytic
ALFGKDHI_00395 7.1e-172 tesB I Thioesterase-like superfamily
ALFGKDHI_00396 1.3e-77 S Protein of unknown function (DUF3180)
ALFGKDHI_00397 2.1e-293 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ALFGKDHI_00398 6.2e-165 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ALFGKDHI_00399 4.5e-100 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
ALFGKDHI_00400 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ALFGKDHI_00401 9.4e-98 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
ALFGKDHI_00402 6e-213 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
ALFGKDHI_00403 1.6e-261 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
ALFGKDHI_00404 5e-309
ALFGKDHI_00405 1.7e-168 natA V ATPases associated with a variety of cellular activities
ALFGKDHI_00406 1.3e-232 epsG M Glycosyl transferase family 21
ALFGKDHI_00407 5.7e-273 S AI-2E family transporter
ALFGKDHI_00408 4.3e-177 3.4.14.13 M Glycosyltransferase like family 2
ALFGKDHI_00409 8.1e-205 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
ALFGKDHI_00412 2.6e-68 S Domain of unknown function (DUF4190)
ALFGKDHI_00413 1.2e-199 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
ALFGKDHI_00414 4.8e-176 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
ALFGKDHI_00416 1.7e-268 lacS G Psort location CytoplasmicMembrane, score 10.00
ALFGKDHI_00417 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
ALFGKDHI_00418 1.7e-90 nagA 3.5.1.25 G Amidohydrolase family
ALFGKDHI_00419 5.4e-181 lacR K Transcriptional regulator, LacI family
ALFGKDHI_00420 4e-229 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
ALFGKDHI_00421 3.9e-119 K Transcriptional regulatory protein, C terminal
ALFGKDHI_00422 4.8e-101
ALFGKDHI_00423 1.8e-95 V N-Acetylmuramoyl-L-alanine amidase
ALFGKDHI_00424 1.6e-143 L IstB-like ATP binding protein
ALFGKDHI_00425 5.8e-296 L PFAM Integrase catalytic
ALFGKDHI_00426 3.2e-59 V N-Acetylmuramoyl-L-alanine amidase
ALFGKDHI_00427 7.4e-109 ytrE V ABC transporter
ALFGKDHI_00428 1.5e-171
ALFGKDHI_00430 4.7e-220 vex3 V ABC transporter permease
ALFGKDHI_00431 2.8e-211 vex1 V Efflux ABC transporter, permease protein
ALFGKDHI_00432 4.9e-111 vex2 V ABC transporter, ATP-binding protein
ALFGKDHI_00433 5.7e-49 azlD E Branched-chain amino acid transport protein (AzlD)
ALFGKDHI_00434 1.1e-195 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
ALFGKDHI_00435 1.8e-95 ptpA 3.1.3.48 T low molecular weight
ALFGKDHI_00436 4.6e-128 folA 1.5.1.3 H dihydrofolate reductase
ALFGKDHI_00437 1.9e-174 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ALFGKDHI_00438 1e-72 attW O OsmC-like protein
ALFGKDHI_00439 4.6e-191 T Universal stress protein family
ALFGKDHI_00440 1.2e-106 M NlpC/P60 family
ALFGKDHI_00441 6.1e-172 usp 3.5.1.28 CBM50 S CHAP domain
ALFGKDHI_00442 2.5e-214 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ALFGKDHI_00443 3.1e-39
ALFGKDHI_00444 2.7e-217 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
ALFGKDHI_00445 1.7e-117 phoU P Plays a role in the regulation of phosphate uptake
ALFGKDHI_00446 4.9e-139 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ALFGKDHI_00447 4.3e-175 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
ALFGKDHI_00448 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
ALFGKDHI_00450 3.6e-216 araJ EGP Major facilitator Superfamily
ALFGKDHI_00451 0.0 S Domain of unknown function (DUF4037)
ALFGKDHI_00452 6.1e-111 S Protein of unknown function (DUF4125)
ALFGKDHI_00453 8.4e-123
ALFGKDHI_00454 1.2e-289 pspC KT PspC domain
ALFGKDHI_00455 1.5e-264 tcsS3 KT PspC domain
ALFGKDHI_00456 8.5e-126 degU K helix_turn_helix, Lux Regulon
ALFGKDHI_00457 4.5e-277 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ALFGKDHI_00458 7.3e-141 pgl 3.1.1.31 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
ALFGKDHI_00459 7.2e-186 opcA G Glucose-6-phosphate dehydrogenase subunit
ALFGKDHI_00460 0.0 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ALFGKDHI_00461 1.3e-93
ALFGKDHI_00463 0.0 nagLU 3.1.4.53, 3.2.1.21, 3.2.1.50 GH3 G Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
ALFGKDHI_00465 3.3e-229 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ALFGKDHI_00466 0.0 nucH 3.1.3.5 F 5'-nucleotidase, C-terminal domain
ALFGKDHI_00467 5.1e-212 I Diacylglycerol kinase catalytic domain
ALFGKDHI_00468 7.6e-152 arbG K CAT RNA binding domain
ALFGKDHI_00469 0.0 crr G pts system, glucose-specific IIABC component
ALFGKDHI_00470 6.5e-53 K Transcriptional regulator
ALFGKDHI_00471 6.8e-43 M Spy0128-like isopeptide containing domain
ALFGKDHI_00472 8.7e-39 M Spy0128-like isopeptide containing domain
ALFGKDHI_00473 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
ALFGKDHI_00474 4.4e-261 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ALFGKDHI_00475 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
ALFGKDHI_00476 2.9e-204 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ALFGKDHI_00477 2e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ALFGKDHI_00479 3.6e-106
ALFGKDHI_00480 1e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ALFGKDHI_00481 3.2e-231 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
ALFGKDHI_00482 4.2e-231 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ALFGKDHI_00483 4.7e-84 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ALFGKDHI_00484 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ALFGKDHI_00485 8e-188 nusA K Participates in both transcription termination and antitermination
ALFGKDHI_00486 2.5e-162
ALFGKDHI_00487 1.5e-99 L Transposase and inactivated derivatives
ALFGKDHI_00489 5e-153 E Transglutaminase/protease-like homologues
ALFGKDHI_00490 0.0 gcs2 S A circularly permuted ATPgrasp
ALFGKDHI_00491 6.4e-173 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
ALFGKDHI_00492 0.0 3.2.1.52 GH20 G hydrolase family 20, catalytic
ALFGKDHI_00493 2.1e-64 rplQ J Ribosomal protein L17
ALFGKDHI_00494 8.9e-184 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ALFGKDHI_00495 1.1e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ALFGKDHI_00496 3.3e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ALFGKDHI_00497 6.5e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
ALFGKDHI_00498 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ALFGKDHI_00499 3.8e-99 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
ALFGKDHI_00500 4.7e-249 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
ALFGKDHI_00501 6.1e-63 rplO J binds to the 23S rRNA
ALFGKDHI_00502 1e-24 rpmD J Ribosomal protein L30p/L7e
ALFGKDHI_00503 1.5e-100 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ALFGKDHI_00504 1.1e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ALFGKDHI_00505 2.1e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ALFGKDHI_00506 4.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ALFGKDHI_00507 9.2e-18 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ALFGKDHI_00508 2.2e-102 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ALFGKDHI_00509 3.5e-52 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ALFGKDHI_00510 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ALFGKDHI_00511 3.5e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ALFGKDHI_00512 5e-38 rpmC J Belongs to the universal ribosomal protein uL29 family
ALFGKDHI_00513 5.8e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ALFGKDHI_00514 7.5e-96 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ALFGKDHI_00515 4.3e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ALFGKDHI_00516 4.1e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ALFGKDHI_00517 4.2e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ALFGKDHI_00518 2.6e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
ALFGKDHI_00519 3.9e-119 rplD J Forms part of the polypeptide exit tunnel
ALFGKDHI_00520 4.2e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ALFGKDHI_00521 5.2e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
ALFGKDHI_00522 1.4e-58 ywiC S YwiC-like protein
ALFGKDHI_00523 1.5e-86 ywiC S YwiC-like protein
ALFGKDHI_00524 8.7e-167 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
ALFGKDHI_00525 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
ALFGKDHI_00526 5.3e-231 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
ALFGKDHI_00527 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
ALFGKDHI_00528 8.8e-68 rpsI J Belongs to the universal ribosomal protein uS9 family
ALFGKDHI_00529 3.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ALFGKDHI_00530 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
ALFGKDHI_00531 3e-120
ALFGKDHI_00532 6.2e-114 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
ALFGKDHI_00533 3.6e-257 M Bacterial capsule synthesis protein PGA_cap
ALFGKDHI_00535 1.4e-237 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ALFGKDHI_00536 1.4e-223 dapC E Aminotransferase class I and II
ALFGKDHI_00537 7.6e-60 fdxA C 4Fe-4S binding domain
ALFGKDHI_00538 2.2e-213 murB 1.3.1.98 M Cell wall formation
ALFGKDHI_00539 1.9e-25 rpmG J Ribosomal protein L33
ALFGKDHI_00543 6e-43 moxR S ATPase family associated with various cellular activities (AAA)
ALFGKDHI_00544 2.6e-127 bla1 3.5.2.6 V Beta-lactamase enzyme family
ALFGKDHI_00545 1.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ALFGKDHI_00546 3.9e-142
ALFGKDHI_00547 2e-93 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
ALFGKDHI_00548 5.4e-121 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
ALFGKDHI_00549 3.2e-38 fmdB S Putative regulatory protein
ALFGKDHI_00550 3.6e-109 flgA NO SAF
ALFGKDHI_00551 9.6e-42
ALFGKDHI_00552 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
ALFGKDHI_00553 3.5e-241 T Forkhead associated domain
ALFGKDHI_00555 1.3e-37 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
ALFGKDHI_00556 2.1e-88 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ALFGKDHI_00557 1.9e-181 xynB2 1.1.1.169 E lipolytic protein G-D-S-L family
ALFGKDHI_00558 0.0 guxA1 3.2.1.18, 3.2.1.91 GH33,GH6 G BNR repeat-like domain
ALFGKDHI_00560 8.8e-222 pbuO S Permease family
ALFGKDHI_00561 1.4e-12 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
ALFGKDHI_00562 1.1e-169 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
ALFGKDHI_00563 3.6e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
ALFGKDHI_00564 5.3e-179 pstA P Phosphate transport system permease
ALFGKDHI_00565 3.8e-171 pstC P probably responsible for the translocation of the substrate across the membrane
ALFGKDHI_00566 6.8e-172 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
ALFGKDHI_00567 3.7e-128 KT Transcriptional regulatory protein, C terminal
ALFGKDHI_00568 9.4e-245 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
ALFGKDHI_00569 1.9e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ALFGKDHI_00570 1.7e-240 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ALFGKDHI_00571 2.8e-108 K helix_turn_helix, Arsenical Resistance Operon Repressor
ALFGKDHI_00572 9.9e-242 EGP Major facilitator Superfamily
ALFGKDHI_00573 1.1e-219 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ALFGKDHI_00574 1.8e-171 L Excalibur calcium-binding domain
ALFGKDHI_00575 9.3e-269 pepC 3.4.22.40 E Peptidase C1-like family
ALFGKDHI_00576 3.3e-54 D nuclear chromosome segregation
ALFGKDHI_00577 8e-128 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ALFGKDHI_00578 1.1e-144 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
ALFGKDHI_00579 5.1e-187 yfiH Q Multi-copper polyphenol oxidoreductase laccase
ALFGKDHI_00580 0.0 yegQ O Peptidase family U32 C-terminal domain
ALFGKDHI_00581 3.1e-98 L Transposase and inactivated derivatives IS30 family
ALFGKDHI_00582 4.6e-168 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
ALFGKDHI_00583 1.4e-40 nrdH O Glutaredoxin
ALFGKDHI_00584 1.9e-98 nrdI F Probably involved in ribonucleotide reductase function
ALFGKDHI_00585 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ALFGKDHI_00586 1e-187 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ALFGKDHI_00587 4e-77 megL 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
ALFGKDHI_00588 0.0 S Predicted membrane protein (DUF2207)
ALFGKDHI_00589 3.7e-94 lemA S LemA family
ALFGKDHI_00590 1.2e-115 xylR K purine nucleotide biosynthetic process
ALFGKDHI_00591 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
ALFGKDHI_00592 3e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ALFGKDHI_00593 4.9e-117
ALFGKDHI_00594 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
ALFGKDHI_00596 1.3e-162 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
ALFGKDHI_00597 3.2e-98 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
ALFGKDHI_00598 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
ALFGKDHI_00599 7.2e-308 pccB I Carboxyl transferase domain
ALFGKDHI_00600 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
ALFGKDHI_00601 2.1e-92 bioY S BioY family
ALFGKDHI_00602 1.3e-151 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
ALFGKDHI_00603 0.0
ALFGKDHI_00604 1e-145 QT PucR C-terminal helix-turn-helix domain
ALFGKDHI_00605 1e-130 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
ALFGKDHI_00606 8.7e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
ALFGKDHI_00607 1.5e-283 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ALFGKDHI_00608 2.7e-166 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ALFGKDHI_00609 0.0 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ALFGKDHI_00610 5e-148 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ALFGKDHI_00611 2.5e-60 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ALFGKDHI_00612 7.6e-30 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ALFGKDHI_00614 6e-146 atpB C it plays a direct role in the translocation of protons across the membrane
ALFGKDHI_00615 4.1e-208 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ALFGKDHI_00617 6.1e-22 S Ribonuclease toxin, BrnT, of type II toxin-antitoxin system
ALFGKDHI_00618 7e-41
ALFGKDHI_00619 0.0 K RNA polymerase II activating transcription factor binding
ALFGKDHI_00620 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
ALFGKDHI_00621 5.2e-92 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ALFGKDHI_00622 9.5e-101 mntP P Probably functions as a manganese efflux pump
ALFGKDHI_00623 4.1e-125
ALFGKDHI_00624 2e-135 KT Transcriptional regulatory protein, C terminal
ALFGKDHI_00625 3e-127 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ALFGKDHI_00626 1.5e-294 E Bacterial extracellular solute-binding proteins, family 5 Middle
ALFGKDHI_00627 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
ALFGKDHI_00628 0.0 S domain protein
ALFGKDHI_00629 4.7e-73 tyrA 5.4.99.5 E Chorismate mutase type II
ALFGKDHI_00630 3.1e-90 lrp_3 K helix_turn_helix ASNC type
ALFGKDHI_00631 4.7e-235 E Aminotransferase class I and II
ALFGKDHI_00632 3e-306 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ALFGKDHI_00633 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
ALFGKDHI_00634 7.4e-52 S Protein of unknown function (DUF2469)
ALFGKDHI_00635 1.7e-198 2.3.1.57 J Acetyltransferase (GNAT) domain
ALFGKDHI_00636 1.4e-286 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ALFGKDHI_00637 6.4e-290 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
ALFGKDHI_00638 6.2e-48 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ALFGKDHI_00639 4.8e-15 V ABC transporter
ALFGKDHI_00640 2.2e-58 V ABC transporter
ALFGKDHI_00641 2e-59 V ABC transporter
ALFGKDHI_00642 7.7e-155 spoU 2.1.1.185 J RNA methyltransferase TrmH family
ALFGKDHI_00643 1e-128 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ALFGKDHI_00644 2.9e-214 rmuC S RmuC family
ALFGKDHI_00645 9.6e-43 csoR S Metal-sensitive transcriptional repressor
ALFGKDHI_00646 0.0 pacS 3.6.3.54 P E1-E2 ATPase
ALFGKDHI_00647 0.0 ubiB S ABC1 family
ALFGKDHI_00648 3.5e-19 S granule-associated protein
ALFGKDHI_00649 2.2e-142 cobQ S CobB/CobQ-like glutamine amidotransferase domain
ALFGKDHI_00650 1.4e-279 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
ALFGKDHI_00651 2.2e-257 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
ALFGKDHI_00652 2.6e-250 dinF V MatE
ALFGKDHI_00653 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
ALFGKDHI_00654 1e-54 glnB K Nitrogen regulatory protein P-II
ALFGKDHI_00655 3.4e-220 amt U Ammonium Transporter Family
ALFGKDHI_00656 4e-202 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
ALFGKDHI_00658 2.3e-115 icaR K Bacterial regulatory proteins, tetR family
ALFGKDHI_00659 1.5e-197 XK27_01805 M Glycosyltransferase like family 2
ALFGKDHI_00660 0.0 S Glycosyl hydrolases related to GH101 family, GH129
ALFGKDHI_00661 4.2e-305 pepD E Peptidase family C69
ALFGKDHI_00663 1.6e-59 XK26_04485 P Cobalt transport protein
ALFGKDHI_00664 9.8e-82
ALFGKDHI_00665 0.0 V ABC transporter transmembrane region
ALFGKDHI_00666 1.8e-301 V ABC transporter, ATP-binding protein
ALFGKDHI_00667 7.7e-82 K Winged helix DNA-binding domain
ALFGKDHI_00668 2.2e-09
ALFGKDHI_00669 8.1e-122 L Integrase core domain
ALFGKDHI_00670 4.7e-40 L Psort location Cytoplasmic, score 8.87
ALFGKDHI_00671 2.1e-88 E IrrE N-terminal-like domain
ALFGKDHI_00673 3.7e-159 S Sucrose-6F-phosphate phosphohydrolase
ALFGKDHI_00674 2.3e-240 S Putative ABC-transporter type IV
ALFGKDHI_00675 7e-81
ALFGKDHI_00676 6.2e-35 Q phosphatase activity
ALFGKDHI_00677 4e-294 bglA 3.2.1.86 GT1 G Glycosyl hydrolase family 1
ALFGKDHI_00678 7.5e-39 celC 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
ALFGKDHI_00679 4.3e-49 celA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
ALFGKDHI_00680 7.3e-250 gmuC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ALFGKDHI_00681 2.9e-69 S haloacid dehalogenase-like hydrolase
ALFGKDHI_00682 1.6e-10 S haloacid dehalogenase-like hydrolase
ALFGKDHI_00683 3.6e-131 yydK K UTRA
ALFGKDHI_00684 1.3e-70 S FMN_bind
ALFGKDHI_00685 5.7e-149 macB V ABC transporter, ATP-binding protein
ALFGKDHI_00686 2.6e-204 Z012_06715 V FtsX-like permease family
ALFGKDHI_00687 4.8e-222 macB_2 V ABC transporter permease
ALFGKDHI_00688 9.2e-234 S Predicted membrane protein (DUF2318)
ALFGKDHI_00689 1.8e-106 tpd P Fe2+ transport protein
ALFGKDHI_00690 4.6e-308 efeU_1 P Iron permease FTR1 family
ALFGKDHI_00691 5.9e-22 G MFS/sugar transport protein
ALFGKDHI_00692 1.1e-200 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
ALFGKDHI_00693 5.4e-57 S Fic/DOC family
ALFGKDHI_00694 3.6e-291 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ALFGKDHI_00695 5e-38 ptsH G PTS HPr component phosphorylation site
ALFGKDHI_00696 4.4e-200 K helix_turn _helix lactose operon repressor
ALFGKDHI_00697 6.3e-213 holB 2.7.7.7 L DNA polymerase III
ALFGKDHI_00698 1.3e-118 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ALFGKDHI_00699 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ALFGKDHI_00700 3.9e-188 3.6.1.27 I PAP2 superfamily
ALFGKDHI_00701 0.0 vpr M PA domain
ALFGKDHI_00702 3.2e-124 yplQ S Haemolysin-III related
ALFGKDHI_00703 9.3e-233 glf 5.4.99.9 M UDP-galactopyranose mutase
ALFGKDHI_00704 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
ALFGKDHI_00705 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ALFGKDHI_00706 3.5e-279 S Calcineurin-like phosphoesterase
ALFGKDHI_00707 3e-15 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
ALFGKDHI_00708 1e-284 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
ALFGKDHI_00709 1.7e-116
ALFGKDHI_00710 6.5e-212 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ALFGKDHI_00712 2e-95 askB 1.1.1.3, 2.7.2.4 E ACT domain
ALFGKDHI_00713 5.3e-136 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
ALFGKDHI_00714 6.7e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ALFGKDHI_00715 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
ALFGKDHI_00716 2.4e-214 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
ALFGKDHI_00717 3.1e-57 S TIGRFAM helicase secretion neighborhood TadE-like protein
ALFGKDHI_00718 3.2e-41 S Protein of unknown function (DUF4244)
ALFGKDHI_00719 3.2e-15 gspF NU Type II secretion system (T2SS), protein F
ALFGKDHI_00720 1.8e-14 gspF NU Type II secretion system (T2SS), protein F
ALFGKDHI_00721 5.7e-121 U Type ii secretion system
ALFGKDHI_00722 3.4e-191 cpaF U Type II IV secretion system protein
ALFGKDHI_00723 7.5e-152 cpaE D bacterial-type flagellum organization
ALFGKDHI_00725 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ALFGKDHI_00726 6.3e-201 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
ALFGKDHI_00727 1e-91
ALFGKDHI_00728 1.7e-45 cbiM P PDGLE domain
ALFGKDHI_00729 2.8e-28 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
ALFGKDHI_00730 1.8e-209 S Glycosyltransferase, group 2 family protein
ALFGKDHI_00731 5.2e-277
ALFGKDHI_00732 4.3e-26 thiS 2.8.1.10 H ThiS family
ALFGKDHI_00733 7e-164 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
ALFGKDHI_00734 0.0 S Psort location Cytoplasmic, score 8.87
ALFGKDHI_00735 0.0 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
ALFGKDHI_00736 1.1e-246 V ABC transporter permease
ALFGKDHI_00737 3.2e-173 V ABC transporter
ALFGKDHI_00738 7.9e-137 T HD domain
ALFGKDHI_00739 3e-164 S Glutamine amidotransferase domain
ALFGKDHI_00741 0.0 kup P Transport of potassium into the cell
ALFGKDHI_00742 6.5e-184 tatD L TatD related DNase
ALFGKDHI_00743 2.5e-16 G MFS/sugar transport protein
ALFGKDHI_00744 2e-257 xylR 5.3.1.12 G MFS/sugar transport protein
ALFGKDHI_00746 6.6e-79 K Transcriptional regulator
ALFGKDHI_00747 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ALFGKDHI_00748 1e-129
ALFGKDHI_00749 8.6e-59
ALFGKDHI_00750 2.3e-168 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ALFGKDHI_00751 2.7e-126 dedA S SNARE associated Golgi protein
ALFGKDHI_00753 3.5e-134 S HAD hydrolase, family IA, variant 3
ALFGKDHI_00754 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR Asp-box repeat
ALFGKDHI_00755 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR repeat-like domain
ALFGKDHI_00756 5.2e-87 hspR K transcriptional regulator, MerR family
ALFGKDHI_00757 7.1e-173 dnaJ1 O DnaJ molecular chaperone homology domain
ALFGKDHI_00758 5.3e-58 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ALFGKDHI_00759 0.0 dnaK O Heat shock 70 kDa protein
ALFGKDHI_00760 0.0 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
ALFGKDHI_00761 1e-190 K Psort location Cytoplasmic, score
ALFGKDHI_00764 1.2e-131 G Phosphoglycerate mutase family
ALFGKDHI_00765 3.9e-63 S Protein of unknown function (DUF4235)
ALFGKDHI_00766 2.3e-142 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
ALFGKDHI_00767 1.1e-45
ALFGKDHI_00768 3.5e-159 neo 2.7.1.87, 2.7.1.95 F Phosphotransferase enzyme family
ALFGKDHI_00769 8.8e-15 S COG NOG14600 non supervised orthologous group
ALFGKDHI_00770 1.7e-142 cobB2 K Sir2 family
ALFGKDHI_00771 1.7e-234 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
ALFGKDHI_00772 1.1e-83 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
ALFGKDHI_00773 3.9e-144 ypfH S Phospholipase/Carboxylesterase
ALFGKDHI_00774 0.0 yjcE P Sodium/hydrogen exchanger family
ALFGKDHI_00775 5.3e-112 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
ALFGKDHI_00776 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
ALFGKDHI_00777 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
ALFGKDHI_00779 1.9e-173 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ALFGKDHI_00780 8e-271 KLT Domain of unknown function (DUF4032)
ALFGKDHI_00781 1.3e-154
ALFGKDHI_00782 6.9e-181 3.4.22.70 M Sortase family
ALFGKDHI_00783 4.4e-182 M LPXTG-motif cell wall anchor domain protein
ALFGKDHI_00784 1.2e-26 M LPXTG-motif cell wall anchor domain protein
ALFGKDHI_00785 5.3e-15 M LPXTG-motif cell wall anchor domain protein
ALFGKDHI_00786 9e-15 S LPXTG-motif cell wall anchor domain protein
ALFGKDHI_00787 1.3e-107 S Phosphatidylethanolamine-binding protein
ALFGKDHI_00788 0.0 pepD E Peptidase family C69
ALFGKDHI_00789 1.3e-287 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
ALFGKDHI_00790 1.3e-62 S Macrophage migration inhibitory factor (MIF)
ALFGKDHI_00791 6.8e-98 S GtrA-like protein
ALFGKDHI_00792 4e-262 EGP Major facilitator Superfamily
ALFGKDHI_00793 2.8e-125 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
ALFGKDHI_00794 5.4e-143
ALFGKDHI_00795 1.7e-137 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
ALFGKDHI_00796 3.3e-200 P NMT1/THI5 like
ALFGKDHI_00797 7.5e-123 S HAD hydrolase, family IA, variant 3
ALFGKDHI_00799 2e-296 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ALFGKDHI_00800 9e-95 S Domain of unknown function (DUF4143)
ALFGKDHI_00801 3.3e-43 S Domain of unknown function (DUF4143)
ALFGKDHI_00804 3.4e-252 S Calcineurin-like phosphoesterase
ALFGKDHI_00805 4.8e-138 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
ALFGKDHI_00806 8.4e-273 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ALFGKDHI_00807 3.8e-133 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ALFGKDHI_00808 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
ALFGKDHI_00810 1.9e-182 S CAAX protease self-immunity
ALFGKDHI_00811 2.1e-221 pyrD 1.3.1.14, 1.3.98.1 F Dihydroorotate dehydrogenase
ALFGKDHI_00812 9.8e-255 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ALFGKDHI_00813 3.3e-226 G Transmembrane secretion effector
ALFGKDHI_00814 4.8e-131 K Bacterial regulatory proteins, tetR family
ALFGKDHI_00815 4.1e-127
ALFGKDHI_00816 2.3e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ALFGKDHI_00817 6.1e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
ALFGKDHI_00818 6.3e-166 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
ALFGKDHI_00819 5.1e-185
ALFGKDHI_00820 7.9e-180
ALFGKDHI_00821 1.3e-163 trxA2 O Tetratricopeptide repeat
ALFGKDHI_00822 1.4e-118 cyaA 4.6.1.1 S CYTH
ALFGKDHI_00825 1.8e-184 K Bacterial regulatory proteins, lacI family
ALFGKDHI_00826 1.6e-17 4.2.1.68 M carboxylic acid catabolic process
ALFGKDHI_00827 9.5e-41 4.2.1.68 M Enolase C-terminal domain-like
ALFGKDHI_00828 3.4e-163 IQ KR domain
ALFGKDHI_00830 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
ALFGKDHI_00831 5.2e-63 psp1 3.5.99.10 J Endoribonuclease L-PSP
ALFGKDHI_00832 3.4e-180 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
ALFGKDHI_00833 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
ALFGKDHI_00834 8.2e-304 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
ALFGKDHI_00835 1.9e-81 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
ALFGKDHI_00836 4.6e-280 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
ALFGKDHI_00837 5.2e-240 hom 1.1.1.3 E Homoserine dehydrogenase
ALFGKDHI_00838 3.5e-188 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
ALFGKDHI_00839 2.3e-278 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
ALFGKDHI_00840 5.8e-67
ALFGKDHI_00841 2.1e-58
ALFGKDHI_00842 3.2e-164 V ATPases associated with a variety of cellular activities
ALFGKDHI_00843 3.3e-256 V Efflux ABC transporter, permease protein
ALFGKDHI_00844 2.2e-168 mdcF S Transporter, auxin efflux carrier (AEC) family protein
ALFGKDHI_00845 7.6e-241 dapE 3.5.1.18 E Peptidase dimerisation domain
ALFGKDHI_00846 0.0 rne 3.1.26.12 J Ribonuclease E/G family
ALFGKDHI_00847 3.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
ALFGKDHI_00848 3.1e-40 rpmA J Ribosomal L27 protein
ALFGKDHI_00849 1.1e-214 K Psort location Cytoplasmic, score
ALFGKDHI_00850 1.1e-298 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ALFGKDHI_00851 4.1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ALFGKDHI_00852 2e-230 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
ALFGKDHI_00854 5.2e-31 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
ALFGKDHI_00855 1.8e-116 nusG K Participates in transcription elongation, termination and antitermination
ALFGKDHI_00856 2.8e-173 plsC2 2.3.1.51 I Phosphate acyltransferases
ALFGKDHI_00857 9.5e-178 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
ALFGKDHI_00858 8.3e-218 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
ALFGKDHI_00859 3.7e-201 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
ALFGKDHI_00860 0.0 3.2.1.97 GH101 G Glycosyl hydrolase 101 beta sandwich domain
ALFGKDHI_00861 2e-191 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ALFGKDHI_00862 0.0 ftsK 2.7.11.1, 2.7.7.7, 3.4.21.110, 4.2.1.2 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ALFGKDHI_00863 2e-113
ALFGKDHI_00865 8.8e-168 T Pfam Adenylate and Guanylate cyclase catalytic domain
ALFGKDHI_00866 6.1e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
ALFGKDHI_00867 1.1e-79 ssb1 L Single-stranded DNA-binding protein
ALFGKDHI_00868 2e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ALFGKDHI_00869 6.6e-70 rplI J Binds to the 23S rRNA
ALFGKDHI_00870 2e-35 S Parallel beta-helix repeats
ALFGKDHI_00871 5.5e-68 E Domain of unknown function (DUF5011)
ALFGKDHI_00874 3.7e-131 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
ALFGKDHI_00875 3e-129 M Protein of unknown function (DUF3152)
ALFGKDHI_00876 5.4e-186 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
ALFGKDHI_00877 5e-148 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ALFGKDHI_00878 3.6e-53 acyP 3.6.1.7 C Acylphosphatase
ALFGKDHI_00879 0.0 inlJ M domain protein
ALFGKDHI_00880 2.1e-280 M LPXTG cell wall anchor motif
ALFGKDHI_00881 8.2e-213 3.4.22.70 M Sortase family
ALFGKDHI_00882 8.5e-60 S Domain of unknown function (DUF4854)
ALFGKDHI_00883 2.4e-155 fahA Q Fumarylacetoacetate (FAA) hydrolase family
ALFGKDHI_00884 2.5e-30 2.1.1.72 S Protein conserved in bacteria
ALFGKDHI_00885 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
ALFGKDHI_00886 2.7e-132 M Mechanosensitive ion channel
ALFGKDHI_00887 1.7e-119 K Bacterial regulatory proteins, tetR family
ALFGKDHI_00888 3.7e-207 MA20_36090 S Psort location Cytoplasmic, score 8.87
ALFGKDHI_00889 1e-231 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
ALFGKDHI_00890 2e-65
ALFGKDHI_00892 4.5e-45 K Transcriptional regulator
ALFGKDHI_00893 0.0 fadD 6.2.1.3 I AMP-binding enzyme
ALFGKDHI_00894 3.5e-07 S Scramblase
ALFGKDHI_00895 6.5e-12
ALFGKDHI_00900 1.2e-129 tam 2.1.1.144, 2.1.1.197 S Methyltransferase domain
ALFGKDHI_00901 1.9e-236 K Helix-turn-helix XRE-family like proteins
ALFGKDHI_00902 3.7e-54 relB L RelB antitoxin
ALFGKDHI_00903 2.6e-17 T Toxic component of a toxin-antitoxin (TA) module
ALFGKDHI_00904 1.7e-131 K helix_turn_helix, mercury resistance
ALFGKDHI_00905 6.6e-243 yxiO S Vacuole effluxer Atg22 like
ALFGKDHI_00907 6.5e-201 yegV G pfkB family carbohydrate kinase
ALFGKDHI_00908 1.4e-29 rpmB J Ribosomal L28 family
ALFGKDHI_00909 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
ALFGKDHI_00910 2.9e-219 steT E amino acid
ALFGKDHI_00913 0.0
ALFGKDHI_00914 9e-250 U Sodium:dicarboxylate symporter family
ALFGKDHI_00915 1.7e-120 rsmD 2.1.1.171 L Conserved hypothetical protein 95
ALFGKDHI_00916 6.3e-108 XK27_02070 S Nitroreductase family
ALFGKDHI_00917 3.8e-81 hsp20 O Hsp20/alpha crystallin family
ALFGKDHI_00918 4.3e-162 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
ALFGKDHI_00919 6.4e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ALFGKDHI_00920 1.8e-34 CP_0960 S Belongs to the UPF0109 family
ALFGKDHI_00921 1e-54 rpsP J Belongs to the bacterial ribosomal protein bS16 family
ALFGKDHI_00922 1.5e-294 ydfD EK Alanine-glyoxylate amino-transferase
ALFGKDHI_00923 1.3e-93 argO S LysE type translocator
ALFGKDHI_00924 1.9e-222 S Endonuclease/Exonuclease/phosphatase family
ALFGKDHI_00925 3.2e-271 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ALFGKDHI_00926 1.4e-164 P Cation efflux family
ALFGKDHI_00927 0.0 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
ALFGKDHI_00928 2.3e-136 guaA1 6.3.5.2 F Peptidase C26
ALFGKDHI_00929 0.0 yjjK S ABC transporter
ALFGKDHI_00930 2e-58 S Protein of unknown function (DUF3039)
ALFGKDHI_00931 2.4e-89 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ALFGKDHI_00932 6.1e-107
ALFGKDHI_00933 4.3e-112 yceD S Uncharacterized ACR, COG1399
ALFGKDHI_00934 2.3e-19 rpmF J Belongs to the bacterial ribosomal protein bL32 family
ALFGKDHI_00935 6.1e-140 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
ALFGKDHI_00936 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
ALFGKDHI_00937 7.6e-92 ilvN 2.2.1.6 E ACT domain
ALFGKDHI_00938 6e-15 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ALFGKDHI_00939 5.7e-247 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ALFGKDHI_00940 2.1e-134 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ALFGKDHI_00941 1.7e-117 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ALFGKDHI_00942 1.7e-174 S Auxin Efflux Carrier
ALFGKDHI_00945 0.0 pgi 5.3.1.9 G Belongs to the GPI family
ALFGKDHI_00946 1.5e-190
ALFGKDHI_00948 3.5e-19
ALFGKDHI_00949 5.4e-170
ALFGKDHI_00951 3e-120 mgtC S MgtC family
ALFGKDHI_00952 0.0 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
ALFGKDHI_00953 6.9e-24 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
ALFGKDHI_00954 3.5e-277 abcT3 P ATPases associated with a variety of cellular activities
ALFGKDHI_00955 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
ALFGKDHI_00956 1.4e-173 K Putative sugar-binding domain
ALFGKDHI_00957 4e-213 gatC G PTS system sugar-specific permease component
ALFGKDHI_00958 1.1e-294 2.7.1.53 G FGGY family of carbohydrate kinases, C-terminal domain
ALFGKDHI_00959 1.1e-172 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
ALFGKDHI_00960 1.1e-129 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
ALFGKDHI_00961 5.6e-62 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
ALFGKDHI_00962 3.1e-158 lepB 3.4.21.89 U Belongs to the peptidase S26 family
ALFGKDHI_00963 2.5e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ALFGKDHI_00964 4.4e-208 K helix_turn _helix lactose operon repressor
ALFGKDHI_00965 1.1e-09 tnp7109-21 L Integrase core domain
ALFGKDHI_00966 0.0 fadD 6.2.1.3 I AMP-binding enzyme
ALFGKDHI_00967 6.9e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ALFGKDHI_00968 3.7e-111 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ALFGKDHI_00971 2.2e-174 G Glycosyl hydrolases family 43
ALFGKDHI_00972 2.5e-103 G Glycosyl hydrolases family 43
ALFGKDHI_00973 3.2e-201 K helix_turn _helix lactose operon repressor
ALFGKDHI_00974 6.2e-10 3.2.1.14 GH18 EM Domain of unknown function (DUF5011)
ALFGKDHI_00975 2.9e-170 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
ALFGKDHI_00976 2.9e-122 L Protein of unknown function (DUF1524)
ALFGKDHI_00977 2.5e-226 mntH P H( )-stimulated, divalent metal cation uptake system
ALFGKDHI_00978 5.3e-306 EGP Major facilitator Superfamily
ALFGKDHI_00979 1e-143 rfbP 2.7.8.6 M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
ALFGKDHI_00980 7.1e-94 lacG G Binding-protein-dependent transport system inner membrane component
ALFGKDHI_00981 4.7e-109 M1-530 S Protein of unknown function (DUF4127)
ALFGKDHI_00982 1.3e-57 2.7.1.2 GK ROK family
ALFGKDHI_00983 4.9e-85 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
ALFGKDHI_00986 9.2e-123 topB 5.99.1.2 L DNA topoisomerase
ALFGKDHI_00987 2.7e-64 topB 5.99.1.2 L DNA topoisomerase
ALFGKDHI_00991 2.7e-69
ALFGKDHI_00992 2.7e-58 S pathogenesis
ALFGKDHI_00993 3e-39 L Psort location Cytoplasmic, score 8.87
ALFGKDHI_00994 6.9e-123 L Integrase core domain
ALFGKDHI_00995 1.4e-12 L Transposase
ALFGKDHI_00996 1.6e-103 K cell envelope-related transcriptional attenuator
ALFGKDHI_00998 7e-228
ALFGKDHI_00999 3.9e-179 S G5
ALFGKDHI_01000 1.9e-59 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
ALFGKDHI_01001 1.2e-117 F Domain of unknown function (DUF4916)
ALFGKDHI_01002 2.9e-159 mhpC I Alpha/beta hydrolase family
ALFGKDHI_01003 1.1e-206 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
ALFGKDHI_01004 0.0 enhA_2 S L,D-transpeptidase catalytic domain
ALFGKDHI_01005 4.9e-72 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
ALFGKDHI_01006 1.1e-240 S Uncharacterized conserved protein (DUF2183)
ALFGKDHI_01007 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
ALFGKDHI_01008 4.5e-191 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
ALFGKDHI_01009 9.9e-120 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
ALFGKDHI_01010 1.6e-134 glxR K helix_turn_helix, cAMP Regulatory protein
ALFGKDHI_01011 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
ALFGKDHI_01012 1.9e-219 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
ALFGKDHI_01013 6.7e-227 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
ALFGKDHI_01014 3.1e-139 glpR K DeoR C terminal sensor domain
ALFGKDHI_01015 3.3e-252 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
ALFGKDHI_01016 6.4e-232 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
ALFGKDHI_01017 4.3e-242 EGP Sugar (and other) transporter
ALFGKDHI_01018 4.2e-43 gcvR T Belongs to the UPF0237 family
ALFGKDHI_01019 9.4e-253 S UPF0210 protein
ALFGKDHI_01020 2.9e-10 S UPF0210 protein
ALFGKDHI_01021 9.9e-109
ALFGKDHI_01022 1.9e-07 S Membrane
ALFGKDHI_01024 6.3e-122 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
ALFGKDHI_01025 2.5e-67 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G Putative cell wall binding repeat
ALFGKDHI_01026 5.8e-187 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
ALFGKDHI_01027 1.3e-106
ALFGKDHI_01028 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ALFGKDHI_01029 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ALFGKDHI_01030 1.3e-96 T Forkhead associated domain
ALFGKDHI_01031 3.5e-66 B Belongs to the OprB family
ALFGKDHI_01032 7.5e-166 3.1.3.16 T Sigma factor PP2C-like phosphatases
ALFGKDHI_01033 0.0 E Transglutaminase-like superfamily
ALFGKDHI_01034 8.6e-227 S Protein of unknown function DUF58
ALFGKDHI_01035 3.7e-222 S ATPase family associated with various cellular activities (AAA)
ALFGKDHI_01036 0.0 S Fibronectin type 3 domain
ALFGKDHI_01037 8.3e-268 KLT Protein tyrosine kinase
ALFGKDHI_01038 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
ALFGKDHI_01039 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
ALFGKDHI_01040 4.3e-158 K -acetyltransferase
ALFGKDHI_01041 1.7e-257 G Major Facilitator Superfamily
ALFGKDHI_01042 1.3e-66 gsiA P ATPase activity
ALFGKDHI_01043 6.5e-43 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
ALFGKDHI_01044 6.4e-24 relB L RelB antitoxin
ALFGKDHI_01045 5.3e-56 L Transposase
ALFGKDHI_01046 1e-132 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
ALFGKDHI_01047 1.9e-161 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ALFGKDHI_01048 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ALFGKDHI_01049 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
ALFGKDHI_01050 8.4e-194 O Subtilase family
ALFGKDHI_01051 1.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ALFGKDHI_01052 1.2e-123 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
ALFGKDHI_01053 2.3e-270 S zinc finger
ALFGKDHI_01054 4.8e-120 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
ALFGKDHI_01055 2.9e-229 aspB E Aminotransferase class-V
ALFGKDHI_01056 1.8e-157 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
ALFGKDHI_01057 1.2e-132 tmp1 S Domain of unknown function (DUF4391)
ALFGKDHI_01058 2.6e-149 moeB 2.7.7.80 H ThiF family
ALFGKDHI_01059 1.1e-256 cdr OP Sulfurtransferase TusA
ALFGKDHI_01060 5.3e-181 iunH1 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
ALFGKDHI_01062 7.3e-203 S Endonuclease/Exonuclease/phosphatase family
ALFGKDHI_01063 7.8e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
ALFGKDHI_01064 8.5e-273 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
ALFGKDHI_01065 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
ALFGKDHI_01066 2.5e-140 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ALFGKDHI_01068 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
ALFGKDHI_01069 2.2e-165
ALFGKDHI_01070 9.3e-259 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
ALFGKDHI_01072 0.0 plyA3 3.2.1.18 GH33 M Parallel beta-helix repeats
ALFGKDHI_01073 2.9e-88 K MarR family
ALFGKDHI_01074 0.0 V ABC transporter, ATP-binding protein
ALFGKDHI_01075 0.0 V ABC transporter transmembrane region
ALFGKDHI_01076 3.6e-169 S Patatin-like phospholipase
ALFGKDHI_01077 1.1e-152 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
ALFGKDHI_01078 1.6e-168 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
ALFGKDHI_01079 2.2e-114 S Vitamin K epoxide reductase
ALFGKDHI_01080 8.7e-167 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
ALFGKDHI_01081 1.8e-31 S Protein of unknown function (DUF3107)
ALFGKDHI_01082 5.9e-240 mphA S Aminoglycoside phosphotransferase
ALFGKDHI_01083 1.5e-280 uvrD2 3.6.4.12 L DNA helicase
ALFGKDHI_01084 1.2e-288 S Zincin-like metallopeptidase
ALFGKDHI_01085 7.6e-152 lon T Belongs to the peptidase S16 family
ALFGKDHI_01086 5.7e-47 S Protein of unknown function (DUF3052)
ALFGKDHI_01087 8.1e-196 K helix_turn _helix lactose operon repressor
ALFGKDHI_01088 4e-60 S Thiamine-binding protein
ALFGKDHI_01089 3.5e-163 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
ALFGKDHI_01090 6.9e-231 O AAA domain (Cdc48 subfamily)
ALFGKDHI_01091 1.3e-84
ALFGKDHI_01092 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ALFGKDHI_01093 6.1e-160 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ALFGKDHI_01094 0.0 lacZ 3.2.1.23 G Domain of unknown function (DUF4982)
ALFGKDHI_01095 2.6e-299 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
ALFGKDHI_01096 5.2e-245 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ALFGKDHI_01097 7.3e-231 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ALFGKDHI_01098 4.3e-80 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
ALFGKDHI_01099 1.4e-41 yggT S YGGT family
ALFGKDHI_01100 9.7e-90 3.1.21.3 V DivIVA protein
ALFGKDHI_01101 4e-103 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ALFGKDHI_01102 2e-177 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
ALFGKDHI_01104 6e-63
ALFGKDHI_01105 5.2e-147 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
ALFGKDHI_01106 3.7e-202 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ALFGKDHI_01107 5.9e-197 ftsE D Cell division ATP-binding protein FtsE
ALFGKDHI_01108 9.2e-159 ftsX D Part of the ABC transporter FtsEX involved in cellular division
ALFGKDHI_01109 2.5e-163 usp 3.5.1.28 CBM50 D CHAP domain protein
ALFGKDHI_01110 3e-76 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
ALFGKDHI_01111 4.9e-150 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
ALFGKDHI_01112 6.3e-18
ALFGKDHI_01113 3.3e-23
ALFGKDHI_01114 6.3e-10
ALFGKDHI_01116 2.4e-183 2.7.11.1 NU Tfp pilus assembly protein FimV
ALFGKDHI_01117 3.7e-221 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
ALFGKDHI_01118 3.9e-235 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ALFGKDHI_01119 1.2e-291 I acetylesterase activity
ALFGKDHI_01120 7.8e-143 recO L Involved in DNA repair and RecF pathway recombination
ALFGKDHI_01121 1.5e-154 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ALFGKDHI_01122 1.5e-191 ywqG S Domain of unknown function (DUF1963)
ALFGKDHI_01123 6.5e-15 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
ALFGKDHI_01124 8.8e-39 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
ALFGKDHI_01125 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
ALFGKDHI_01126 1.6e-84 S zinc-ribbon domain
ALFGKDHI_01127 1.6e-46 yhbY J CRS1_YhbY
ALFGKDHI_01128 0.0 4.2.1.53 S MCRA family
ALFGKDHI_01130 1.2e-202 K WYL domain
ALFGKDHI_01131 5e-156 yvgN 1.1.1.346 S Aldo/keto reductase family
ALFGKDHI_01132 6.4e-173 dkgA 1.1.1.346 C Aldo/keto reductase family
ALFGKDHI_01133 1.2e-76 yneG S Domain of unknown function (DUF4186)
ALFGKDHI_01135 3.9e-07 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
ALFGKDHI_01136 2.3e-181 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
ALFGKDHI_01137 1.1e-256 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ALFGKDHI_01138 4.2e-225 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ALFGKDHI_01139 4.2e-112 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
ALFGKDHI_01140 1.3e-112
ALFGKDHI_01141 4.1e-121 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ALFGKDHI_01142 4.9e-131 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
ALFGKDHI_01143 1.4e-283 S Uncharacterized protein conserved in bacteria (DUF2252)
ALFGKDHI_01144 2.1e-265 glnA2 6.3.1.2 E glutamine synthetase
ALFGKDHI_01145 1.8e-251 S Domain of unknown function (DUF5067)
ALFGKDHI_01146 8.7e-60 EGP Major facilitator Superfamily
ALFGKDHI_01147 1.1e-176 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
ALFGKDHI_01148 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
ALFGKDHI_01149 3.5e-120 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
ALFGKDHI_01150 1.2e-171
ALFGKDHI_01151 4.5e-272 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ALFGKDHI_01152 2.3e-176 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
ALFGKDHI_01153 3.3e-164 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ALFGKDHI_01154 7.5e-129 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ALFGKDHI_01155 1.1e-49 M Lysin motif
ALFGKDHI_01156 2.3e-83 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ALFGKDHI_01157 1.7e-229 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
ALFGKDHI_01158 0.0 L DNA helicase
ALFGKDHI_01159 1.3e-90 mraZ K Belongs to the MraZ family
ALFGKDHI_01160 1.6e-205 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
ALFGKDHI_01161 9.7e-64 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ALFGKDHI_01162 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
ALFGKDHI_01163 2.8e-180 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ALFGKDHI_01164 4e-284 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
ALFGKDHI_01165 3.6e-202 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ALFGKDHI_01166 1.2e-266 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ALFGKDHI_01167 4e-224 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
ALFGKDHI_01168 1.7e-218 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ALFGKDHI_01169 6.8e-295 murC 6.3.2.8 M Belongs to the MurCDEF family
ALFGKDHI_01170 1.8e-157 ftsQ 6.3.2.4 D Cell division protein FtsQ
ALFGKDHI_01171 1.3e-37
ALFGKDHI_01173 2.2e-171 L Transposase and inactivated derivatives IS30 family
ALFGKDHI_01174 6.6e-85 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
ALFGKDHI_01175 4.4e-236 G Major Facilitator Superfamily
ALFGKDHI_01176 1.9e-169 2.7.1.4 G pfkB family carbohydrate kinase
ALFGKDHI_01177 1.3e-224 GK ROK family
ALFGKDHI_01178 9.9e-132 cutC P Participates in the control of copper homeostasis
ALFGKDHI_01179 3.5e-216 GK ROK family
ALFGKDHI_01180 6.6e-153 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
ALFGKDHI_01181 1.6e-243 nagA 3.5.1.25 G Amidohydrolase family
ALFGKDHI_01182 1.7e-304 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
ALFGKDHI_01183 6.7e-185 dppB EP Binding-protein-dependent transport system inner membrane component
ALFGKDHI_01184 3.3e-190 dppC EP Binding-protein-dependent transport system inner membrane component
ALFGKDHI_01185 0.0 P Belongs to the ABC transporter superfamily
ALFGKDHI_01186 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
ALFGKDHI_01187 5.6e-97 3.6.1.55 F NUDIX domain
ALFGKDHI_01189 4.7e-283 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
ALFGKDHI_01190 0.0 smc D Required for chromosome condensation and partitioning
ALFGKDHI_01191 8.6e-136 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
ALFGKDHI_01192 9.5e-244 yxbA 6.3.1.12 S ATP-grasp
ALFGKDHI_01193 2.9e-229 2.6.1.33 M DegT/DnrJ/EryC1/StrS aminotransferase family
ALFGKDHI_01194 1.3e-190 V Acetyltransferase (GNAT) domain
ALFGKDHI_01195 5.3e-295 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ALFGKDHI_01196 1.4e-113 sigH K Belongs to the sigma-70 factor family. ECF subfamily
ALFGKDHI_01197 2e-64
ALFGKDHI_01198 1.4e-194 galM 5.1.3.3 G Aldose 1-epimerase
ALFGKDHI_01199 1.6e-180 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ALFGKDHI_01200 2.2e-93 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ALFGKDHI_01201 1e-198 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
ALFGKDHI_01202 7.5e-132 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
ALFGKDHI_01203 1.9e-07 S Spermine/spermidine synthase domain
ALFGKDHI_01204 1.4e-103 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ALFGKDHI_01205 2.1e-25 rpmI J Ribosomal protein L35
ALFGKDHI_01206 9.6e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ALFGKDHI_01207 3.4e-180 xerD D recombinase XerD
ALFGKDHI_01208 1.8e-152 soj D CobQ CobB MinD ParA nucleotide binding domain protein
ALFGKDHI_01209 4.2e-150 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ALFGKDHI_01210 1.6e-112 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ALFGKDHI_01211 1.1e-149 nrtR 3.6.1.55 F NUDIX hydrolase
ALFGKDHI_01212 7.5e-252 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ALFGKDHI_01213 0.0 nadB 1.3.5.4, 1.4.3.16, 2.4.2.19 H Catalyzes the oxidation of L-aspartate to iminoaspartate
ALFGKDHI_01214 3.1e-164 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, N-terminal domain
ALFGKDHI_01215 3.4e-236 iscS1 2.8.1.7 E Aminotransferase class-V
ALFGKDHI_01216 0.0 typA T Elongation factor G C-terminus
ALFGKDHI_01217 2e-81
ALFGKDHI_01218 5.5e-197 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
ALFGKDHI_01219 1.1e-192 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
ALFGKDHI_01220 7.3e-42
ALFGKDHI_01221 1.3e-187 xerC D Belongs to the 'phage' integrase family. XerC subfamily
ALFGKDHI_01222 7.9e-177 appB EP Binding-protein-dependent transport system inner membrane component
ALFGKDHI_01223 3.5e-166 dppC EP N-terminal TM domain of oligopeptide transport permease C
ALFGKDHI_01224 0.0 oppD P Belongs to the ABC transporter superfamily
ALFGKDHI_01225 0.0 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
ALFGKDHI_01226 1.9e-264 pepC 3.4.22.40 E Peptidase C1-like family
ALFGKDHI_01227 4.1e-169 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
ALFGKDHI_01228 3.2e-139 S Protein of unknown function (DUF3710)
ALFGKDHI_01229 9.8e-130 S Protein of unknown function (DUF3159)
ALFGKDHI_01230 1.1e-247 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ALFGKDHI_01231 2e-109
ALFGKDHI_01232 0.0 ctpE P E1-E2 ATPase
ALFGKDHI_01233 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ALFGKDHI_01235 1.1e-166 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
ALFGKDHI_01236 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
ALFGKDHI_01237 1.1e-53 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
ALFGKDHI_01238 1.1e-220 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ALFGKDHI_01239 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ALFGKDHI_01240 3.2e-135 3.8.1.2 S Haloacid dehalogenase-like hydrolase
ALFGKDHI_01241 4.3e-183 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ALFGKDHI_01242 4.3e-138 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
ALFGKDHI_01244 0.0 arc O AAA ATPase forming ring-shaped complexes
ALFGKDHI_01245 0.0 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
ALFGKDHI_01246 2.4e-158 hisN 3.1.3.25 G Inositol monophosphatase family
ALFGKDHI_01247 9.2e-11 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
ALFGKDHI_01248 1e-276 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ALFGKDHI_01249 8.1e-42 hup L Belongs to the bacterial histone-like protein family
ALFGKDHI_01250 0.0 S Lysylphosphatidylglycerol synthase TM region
ALFGKDHI_01251 8.6e-281 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
ALFGKDHI_01252 3.9e-287 S PGAP1-like protein
ALFGKDHI_01254 1e-71
ALFGKDHI_01255 2.1e-148 S von Willebrand factor (vWF) type A domain
ALFGKDHI_01256 2.3e-190 S von Willebrand factor (vWF) type A domain
ALFGKDHI_01257 6.4e-94
ALFGKDHI_01258 1.8e-176 S Protein of unknown function DUF58
ALFGKDHI_01259 5e-196 moxR S ATPase family associated with various cellular activities (AAA)
ALFGKDHI_01260 9.3e-144 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ALFGKDHI_01261 7.6e-71 S LytR cell envelope-related transcriptional attenuator
ALFGKDHI_01262 2.2e-44 cspA K 'Cold-shock' DNA-binding domain
ALFGKDHI_01263 2.7e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
ALFGKDHI_01264 1.7e-10 S Proteins of 100 residues with WXG
ALFGKDHI_01265 3.4e-163
ALFGKDHI_01266 1.6e-134 KT Response regulator receiver domain protein
ALFGKDHI_01267 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
ALFGKDHI_01268 1e-66 cspB K 'Cold-shock' DNA-binding domain
ALFGKDHI_01269 2.1e-191 S Protein of unknown function (DUF3027)
ALFGKDHI_01270 4.7e-185 uspA T Belongs to the universal stress protein A family
ALFGKDHI_01271 0.0 clpC O ATPase family associated with various cellular activities (AAA)
ALFGKDHI_01275 1.1e-216 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
ALFGKDHI_01276 2.4e-264 hisS 6.1.1.21 J Histidyl-tRNA synthetase
ALFGKDHI_01277 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ALFGKDHI_01278 3e-63 K helix_turn_helix, Lux Regulon
ALFGKDHI_01279 1.8e-16 S Aminoacyl-tRNA editing domain
ALFGKDHI_01280 4.5e-58 S Aminoacyl-tRNA editing domain
ALFGKDHI_01281 1e-139 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
ALFGKDHI_01282 4.3e-147 gluB ET Belongs to the bacterial solute-binding protein 3 family
ALFGKDHI_01283 1.8e-111 gluC E Binding-protein-dependent transport system inner membrane component
ALFGKDHI_01284 6.3e-199 gluD E Binding-protein-dependent transport system inner membrane component
ALFGKDHI_01285 6e-194 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
ALFGKDHI_01286 0.0 L DEAD DEAH box helicase
ALFGKDHI_01287 5e-257 rarA L Recombination factor protein RarA
ALFGKDHI_01289 2e-256 EGP Major facilitator Superfamily
ALFGKDHI_01290 0.0 ecfA GP ABC transporter, ATP-binding protein
ALFGKDHI_01291 1.1e-104 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ALFGKDHI_01293 1.7e-139 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
ALFGKDHI_01294 1.7e-212 E Aminotransferase class I and II
ALFGKDHI_01295 5.5e-136 bioM P ATPases associated with a variety of cellular activities
ALFGKDHI_01296 7.5e-70 2.8.2.22 S Arylsulfotransferase Ig-like domain
ALFGKDHI_01297 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ALFGKDHI_01298 0.0 S Tetratricopeptide repeat
ALFGKDHI_01299 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ALFGKDHI_01300 5.3e-209 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
ALFGKDHI_01301 7.5e-160 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
ALFGKDHI_01304 5.1e-19
ALFGKDHI_01306 1.3e-18
ALFGKDHI_01307 1.8e-286 glnA 6.3.1.2 E glutamine synthetase
ALFGKDHI_01308 9.4e-144 S Domain of unknown function (DUF4191)
ALFGKDHI_01309 4.7e-282 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ALFGKDHI_01310 2.7e-103 S Protein of unknown function (DUF3043)
ALFGKDHI_01311 2.3e-259 argE E Peptidase dimerisation domain
ALFGKDHI_01312 7.5e-192 V N-Acetylmuramoyl-L-alanine amidase
ALFGKDHI_01313 5.7e-152 ytrE V ATPases associated with a variety of cellular activities
ALFGKDHI_01314 7.6e-197
ALFGKDHI_01315 2.6e-228 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
ALFGKDHI_01316 0.0 S Uncharacterised protein family (UPF0182)
ALFGKDHI_01317 2.1e-207 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
ALFGKDHI_01318 0.0 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
ALFGKDHI_01319 2.4e-220 I transferase activity, transferring acyl groups other than amino-acyl groups
ALFGKDHI_01321 1.8e-130 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
ALFGKDHI_01322 1.9e-197 GM GDP-mannose 4,6 dehydratase
ALFGKDHI_01323 2.1e-151 GM ABC-2 type transporter
ALFGKDHI_01324 4.9e-145 tagH 3.6.3.38, 3.6.3.40 GM ABC transporter
ALFGKDHI_01325 1.1e-95 2.3.1.183 M Acetyltransferase (GNAT) domain
ALFGKDHI_01326 7.6e-114 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
ALFGKDHI_01327 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ALFGKDHI_01328 1.4e-297 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH chorismate binding enzyme
ALFGKDHI_01329 6.4e-153 pabC 2.6.1.42, 2.6.1.85, 4.1.3.38 E branched-chain-amino-acid transaminase activity
ALFGKDHI_01330 6.9e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
ALFGKDHI_01331 2.5e-101 divIC D Septum formation initiator
ALFGKDHI_01332 2e-106 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
ALFGKDHI_01333 9.8e-183 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
ALFGKDHI_01335 6.1e-97
ALFGKDHI_01336 8.8e-281 sdaA 4.3.1.17 E Serine dehydratase alpha chain
ALFGKDHI_01337 5.7e-73 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
ALFGKDHI_01338 7.5e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
ALFGKDHI_01340 2e-142 yplQ S Haemolysin-III related
ALFGKDHI_01341 7.3e-286 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
ALFGKDHI_01342 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
ALFGKDHI_01343 0.0 D FtsK/SpoIIIE family
ALFGKDHI_01344 2.4e-270 K Cell envelope-related transcriptional attenuator domain
ALFGKDHI_01345 5.8e-54 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
ALFGKDHI_01346 0.0 S Glycosyl transferase, family 2
ALFGKDHI_01347 4.7e-261
ALFGKDHI_01348 6.3e-66 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
ALFGKDHI_01349 3.4e-157 cof 5.2.1.8 T Eukaryotic phosphomannomutase
ALFGKDHI_01350 7.7e-129 ctsW S Phosphoribosyl transferase domain
ALFGKDHI_01351 3.6e-72 rulA 3.4.21.88 KT Peptidase S24-like
ALFGKDHI_01352 1.1e-203 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
ALFGKDHI_01353 7.2e-127 T Response regulator receiver domain protein
ALFGKDHI_01354 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ALFGKDHI_01355 5.1e-102 carD K CarD-like/TRCF domain
ALFGKDHI_01356 1.9e-83 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
ALFGKDHI_01357 4.3e-139 znuB U ABC 3 transport family
ALFGKDHI_01358 1.8e-164 znuC P ATPases associated with a variety of cellular activities
ALFGKDHI_01359 2.1e-172 P Zinc-uptake complex component A periplasmic
ALFGKDHI_01360 2.6e-163 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ALFGKDHI_01361 3.3e-243 rpsA J Ribosomal protein S1
ALFGKDHI_01362 2.7e-106 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ALFGKDHI_01363 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
ALFGKDHI_01364 1.7e-179 terC P Integral membrane protein, TerC family
ALFGKDHI_01365 6.6e-273 pyk 2.7.1.40 G Pyruvate kinase
ALFGKDHI_01366 1.8e-110 aspA 3.6.1.13 L NUDIX domain
ALFGKDHI_01368 9.2e-120 pdtaR T Response regulator receiver domain protein
ALFGKDHI_01369 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ALFGKDHI_01370 2.9e-173 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
ALFGKDHI_01371 1.9e-127 3.6.1.13 L NUDIX domain
ALFGKDHI_01372 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
ALFGKDHI_01373 8.5e-221 ykiI
ALFGKDHI_01375 4.2e-135 L Phage integrase family
ALFGKDHI_01376 2.9e-108 3.4.13.21 E Peptidase family S51
ALFGKDHI_01377 1.2e-274 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
ALFGKDHI_01378 1.3e-232 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ALFGKDHI_01379 0.0 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
ALFGKDHI_01380 1e-281 XK27_07020 S Domain of unknown function (DUF1846)
ALFGKDHI_01381 1.7e-122
ALFGKDHI_01383 9.9e-112 ysdA S Protein of unknown function (DUF1294)
ALFGKDHI_01384 1.2e-27
ALFGKDHI_01385 4.4e-51
ALFGKDHI_01387 1.1e-302 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
ALFGKDHI_01388 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
ALFGKDHI_01389 4.4e-189 pit P Phosphate transporter family
ALFGKDHI_01390 1.1e-115 MA20_27875 P Protein of unknown function DUF47
ALFGKDHI_01391 8.2e-120 K helix_turn_helix, Lux Regulon
ALFGKDHI_01392 3.7e-235 T Histidine kinase
ALFGKDHI_01393 1.2e-42 pacL 3.6.3.8, 3.6.3.9 P ATPase, P-type transporting, HAD superfamily, subfamily IC
ALFGKDHI_01394 4.1e-181 V ATPases associated with a variety of cellular activities
ALFGKDHI_01395 8.1e-227 V ABC-2 family transporter protein
ALFGKDHI_01396 9e-254 V ABC-2 family transporter protein
ALFGKDHI_01397 5.9e-285 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
ALFGKDHI_01398 7.6e-194 L Transposase and inactivated derivatives IS30 family
ALFGKDHI_01400 4.4e-85
ALFGKDHI_01401 1.3e-63 D MobA/MobL family
ALFGKDHI_01402 4.7e-46 L Transposase
ALFGKDHI_01403 4.7e-119 tnp7109-21 L Integrase core domain
ALFGKDHI_01404 2.7e-153 K Transposase IS116 IS110 IS902
ALFGKDHI_01405 7.4e-51 2.1.1.72 S Adenine-specific methyltransferase EcoRI
ALFGKDHI_01406 9.9e-39
ALFGKDHI_01407 8.1e-111 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
ALFGKDHI_01409 7.7e-103 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
ALFGKDHI_01410 2.8e-47 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
ALFGKDHI_01412 1.8e-240 pbuX F Permease family
ALFGKDHI_01413 3e-107 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
ALFGKDHI_01414 0.0 yrhL I Psort location CytoplasmicMembrane, score 9.99
ALFGKDHI_01415 0.0 pcrA 3.6.4.12 L DNA helicase
ALFGKDHI_01416 8.2e-64 S Domain of unknown function (DUF4418)
ALFGKDHI_01417 1.9e-212 V FtsX-like permease family
ALFGKDHI_01418 1.3e-127 lolD V ABC transporter
ALFGKDHI_01419 1e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ALFGKDHI_01420 0.0 oatA I Psort location CytoplasmicMembrane, score 9.99
ALFGKDHI_01421 1.9e-135 pgm3 G Phosphoglycerate mutase family
ALFGKDHI_01422 3.8e-64 WQ51_05790 S Bacterial protein of unknown function (DUF948)
ALFGKDHI_01423 1.1e-36
ALFGKDHI_01424 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ALFGKDHI_01425 3e-75 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ALFGKDHI_01426 2.3e-186 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ALFGKDHI_01427 1.4e-46 3.4.23.43 S Type IV leader peptidase family
ALFGKDHI_01428 6e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ALFGKDHI_01429 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ALFGKDHI_01430 2.2e-78 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
ALFGKDHI_01431 1.2e-15
ALFGKDHI_01432 1.7e-120 K helix_turn_helix, Lux Regulon
ALFGKDHI_01433 2.6e-07 3.4.22.70 M Sortase family
ALFGKDHI_01434 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
ALFGKDHI_01435 3.6e-290 sufB O FeS assembly protein SufB
ALFGKDHI_01436 1.4e-234 sufD O FeS assembly protein SufD
ALFGKDHI_01437 1.4e-144 sufC O FeS assembly ATPase SufC
ALFGKDHI_01438 1.6e-241 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ALFGKDHI_01439 8.8e-101 iscU C SUF system FeS assembly protein, NifU family
ALFGKDHI_01440 1.2e-108 yitW S Iron-sulfur cluster assembly protein
ALFGKDHI_01441 3.1e-242 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ALFGKDHI_01442 4e-164 spoU 2.1.1.185 J SpoU rRNA Methylase family
ALFGKDHI_01444 7.2e-136 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
ALFGKDHI_01445 4.4e-58 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
ALFGKDHI_01446 3.4e-197 phoH T PhoH-like protein
ALFGKDHI_01447 7.4e-100 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ALFGKDHI_01448 1.6e-250 corC S CBS domain
ALFGKDHI_01449 1.5e-186 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ALFGKDHI_01450 0.0 fadD 6.2.1.3 I AMP-binding enzyme
ALFGKDHI_01451 1.1e-201 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
ALFGKDHI_01452 4.4e-44 pntA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
ALFGKDHI_01453 2.3e-233 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ALFGKDHI_01454 4.8e-190 S alpha beta
ALFGKDHI_01455 8.3e-95 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ALFGKDHI_01456 2.4e-225 ilvE 2.6.1.42 E Amino-transferase class IV
ALFGKDHI_01457 4e-46 S phosphoesterase or phosphohydrolase
ALFGKDHI_01458 2.7e-99 3.1.4.37 T RNA ligase
ALFGKDHI_01459 1.2e-135 S UPF0126 domain
ALFGKDHI_01460 9.9e-34 rpsT J Binds directly to 16S ribosomal RNA
ALFGKDHI_01461 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
ALFGKDHI_01462 3.4e-245 hemN H Involved in the biosynthesis of porphyrin-containing compound
ALFGKDHI_01463 4e-13 S Membrane
ALFGKDHI_01464 3.1e-292 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
ALFGKDHI_01465 0.0 tetP J Elongation factor G, domain IV
ALFGKDHI_01466 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
ALFGKDHI_01467 2.7e-304 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
ALFGKDHI_01468 3.6e-82
ALFGKDHI_01469 9.6e-244 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
ALFGKDHI_01470 8.9e-164 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
ALFGKDHI_01471 1.5e-158 ybeM S Carbon-nitrogen hydrolase
ALFGKDHI_01472 1.6e-91 S Sel1-like repeats.
ALFGKDHI_01473 1.2e-185 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
ALFGKDHI_01474 9.1e-138 L Transposase
ALFGKDHI_01475 1.6e-28
ALFGKDHI_01476 3.1e-40 XK26_04895
ALFGKDHI_01477 2.8e-67 XK26_04895
ALFGKDHI_01478 1.3e-245 L Transposase
ALFGKDHI_01479 3e-136 L IstB-like ATP binding protein
ALFGKDHI_01480 7.4e-99 K Psort location Cytoplasmic, score
ALFGKDHI_01481 0.0 L SNF2 family N-terminal domain
ALFGKDHI_01482 0.0 V Type II restriction enzyme, methylase
ALFGKDHI_01483 0.0 L Helicase conserved C-terminal domain
ALFGKDHI_01484 1.7e-229 S Domain of unknown function (DUF1998)
ALFGKDHI_01485 1.3e-41 I PLD-like domain
ALFGKDHI_01486 3.2e-29
ALFGKDHI_01487 6.4e-171 L Transposase and inactivated derivatives IS30 family
ALFGKDHI_01488 1.3e-93 rarD 3.4.17.13 E Rard protein
ALFGKDHI_01489 5.8e-25 rarD S Rard protein
ALFGKDHI_01490 2.8e-176 I alpha/beta hydrolase fold
ALFGKDHI_01491 2.2e-207 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
ALFGKDHI_01492 2.6e-100 sixA T Phosphoglycerate mutase family
ALFGKDHI_01493 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ALFGKDHI_01494 2.4e-158 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
ALFGKDHI_01496 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
ALFGKDHI_01497 1.4e-181 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
ALFGKDHI_01498 2e-73 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
ALFGKDHI_01499 9.4e-280 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
ALFGKDHI_01500 3.4e-180 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
ALFGKDHI_01501 1.9e-155 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
ALFGKDHI_01502 8.2e-179 pyrD 1.3.1.14 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
ALFGKDHI_01503 1.5e-124 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ALFGKDHI_01504 1e-16 K MerR family regulatory protein
ALFGKDHI_01505 5.2e-195 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
ALFGKDHI_01506 2.8e-141
ALFGKDHI_01507 1.3e-16 K Psort location Cytoplasmic, score
ALFGKDHI_01508 9.1e-16 KLT Protein tyrosine kinase
ALFGKDHI_01509 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ALFGKDHI_01510 3.3e-242 vbsD V MatE
ALFGKDHI_01511 2.1e-131 S Enoyl-(Acyl carrier protein) reductase
ALFGKDHI_01512 2.5e-132 magIII L endonuclease III
ALFGKDHI_01513 1.9e-92 laaE K Transcriptional regulator PadR-like family
ALFGKDHI_01514 7e-173 S Membrane transport protein
ALFGKDHI_01515 1.1e-67 4.1.1.44 S Cupin domain
ALFGKDHI_01516 1.7e-223 hipA 2.7.11.1 S HipA N-terminal domain
ALFGKDHI_01517 3.7e-41 K Helix-turn-helix
ALFGKDHI_01518 3.1e-49 tam 2.1.1.144, 2.1.1.197 FG trans-aconitate 2-methyltransferase activity
ALFGKDHI_01519 1.4e-19
ALFGKDHI_01520 2.1e-100 K Bacterial regulatory proteins, tetR family
ALFGKDHI_01521 4.3e-86 T Domain of unknown function (DUF4234)
ALFGKDHI_01522 1.2e-171 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
ALFGKDHI_01523 1.5e-123 3.8.1.2 S Haloacid dehalogenase-like hydrolase
ALFGKDHI_01524 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ALFGKDHI_01525 4e-144 4.1.1.44 S Carboxymuconolactone decarboxylase family
ALFGKDHI_01526 1.3e-90 dkgB S Oxidoreductase, aldo keto reductase family protein
ALFGKDHI_01528 5.1e-289 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
ALFGKDHI_01529 0.0 pafB K WYL domain
ALFGKDHI_01530 1e-51
ALFGKDHI_01531 0.0 helY L DEAD DEAH box helicase
ALFGKDHI_01532 3e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
ALFGKDHI_01533 1.6e-142 pgp 3.1.3.18 S HAD-hyrolase-like
ALFGKDHI_01535 3.6e-90 K Putative zinc ribbon domain
ALFGKDHI_01536 7.2e-126 S GyrI-like small molecule binding domain
ALFGKDHI_01537 3.3e-24 L DNA integration
ALFGKDHI_01539 7.3e-62
ALFGKDHI_01540 3e-119 K helix_turn_helix, mercury resistance
ALFGKDHI_01541 9.6e-74 garA T Inner membrane component of T3SS, cytoplasmic domain
ALFGKDHI_01542 3.4e-141 S Bacterial protein of unknown function (DUF881)
ALFGKDHI_01543 2.6e-31 sbp S Protein of unknown function (DUF1290)
ALFGKDHI_01544 9e-173 S Bacterial protein of unknown function (DUF881)
ALFGKDHI_01545 1e-116 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ALFGKDHI_01546 1.8e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
ALFGKDHI_01547 6.4e-41 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
ALFGKDHI_01548 6.3e-101 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
ALFGKDHI_01549 3.5e-180 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ALFGKDHI_01550 4.9e-162 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
ALFGKDHI_01551 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
ALFGKDHI_01552 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
ALFGKDHI_01553 7.5e-146 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
ALFGKDHI_01554 1.8e-103 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
ALFGKDHI_01555 5.7e-30
ALFGKDHI_01556 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
ALFGKDHI_01557 2.2e-246
ALFGKDHI_01558 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ALFGKDHI_01559 1.3e-224 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
ALFGKDHI_01560 5.5e-101 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ALFGKDHI_01561 2.6e-44 yajC U Preprotein translocase subunit
ALFGKDHI_01562 1.8e-201 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
ALFGKDHI_01563 2.5e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
ALFGKDHI_01564 1.8e-99 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ALFGKDHI_01565 1e-131 yebC K transcriptional regulatory protein
ALFGKDHI_01566 0.0 3.2.1.52 GH20 M Glycosyl hydrolase family 20, catalytic domain
ALFGKDHI_01567 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ALFGKDHI_01568 1.7e-250 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
ALFGKDHI_01572 1.1e-197
ALFGKDHI_01576 2.8e-156 S PAC2 family
ALFGKDHI_01577 5e-168 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
ALFGKDHI_01578 7.1e-160 G Fructosamine kinase
ALFGKDHI_01579 3.4e-211 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
ALFGKDHI_01580 1.1e-204 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
ALFGKDHI_01581 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
ALFGKDHI_01582 1e-201 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ALFGKDHI_01583 1.1e-142 yoaK S Protein of unknown function (DUF1275)
ALFGKDHI_01584 4.4e-253 brnQ U Component of the transport system for branched-chain amino acids
ALFGKDHI_01585 1.2e-239 mepA_6 V MatE
ALFGKDHI_01586 6.1e-162 S Sucrose-6F-phosphate phosphohydrolase
ALFGKDHI_01587 1.3e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
ALFGKDHI_01588 8e-33 secG U Preprotein translocase SecG subunit
ALFGKDHI_01589 5.3e-147 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
ALFGKDHI_01590 2.6e-222 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
ALFGKDHI_01591 3.1e-173 whiA K May be required for sporulation
ALFGKDHI_01592 1.5e-177 rapZ S Displays ATPase and GTPase activities
ALFGKDHI_01593 1.7e-179 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
ALFGKDHI_01594 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
ALFGKDHI_01595 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
ALFGKDHI_01596 2.1e-76
ALFGKDHI_01597 1.6e-59 V MacB-like periplasmic core domain
ALFGKDHI_01598 3.3e-118 K Transcriptional regulatory protein, C terminal
ALFGKDHI_01599 2.9e-236 qseC 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
ALFGKDHI_01600 4.5e-140 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
ALFGKDHI_01601 2.6e-302 ybiT S ABC transporter
ALFGKDHI_01602 7.2e-197 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
ALFGKDHI_01603 1.1e-307 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
ALFGKDHI_01604 1.8e-206 mdsC 2.7.1.162, 2.7.1.39 S Phosphotransferase enzyme family
ALFGKDHI_01605 6.4e-218 GK ROK family
ALFGKDHI_01606 6.9e-178 2.7.1.2 GK ROK family
ALFGKDHI_01607 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
ALFGKDHI_01608 5e-168 G ABC transporter permease
ALFGKDHI_01609 1.1e-173 G Binding-protein-dependent transport system inner membrane component
ALFGKDHI_01610 4.5e-244 G Bacterial extracellular solute-binding protein
ALFGKDHI_01611 1.3e-309 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ALFGKDHI_01612 5.3e-74 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ALFGKDHI_01613 1.4e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
ALFGKDHI_01614 9.8e-230 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
ALFGKDHI_01615 1.8e-176 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
ALFGKDHI_01616 2.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
ALFGKDHI_01617 2.4e-133 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
ALFGKDHI_01618 1.8e-127 3.2.1.8 S alpha beta
ALFGKDHI_01619 4.8e-146 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ALFGKDHI_01620 1.4e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
ALFGKDHI_01621 1.7e-87 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
ALFGKDHI_01622 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
ALFGKDHI_01623 5.7e-91
ALFGKDHI_01624 2.5e-200 guaB 1.1.1.205 F IMP dehydrogenase family protein
ALFGKDHI_01625 3.3e-241 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
ALFGKDHI_01626 3.9e-274 G ABC transporter substrate-binding protein
ALFGKDHI_01627 0.0 fadD1 6.2.1.3 I AMP-binding enzyme
ALFGKDHI_01628 3e-181 M Peptidase family M23
ALFGKDHI_01630 1.1e-195 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ALFGKDHI_01631 9e-104 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
ALFGKDHI_01632 5e-159 yeaZ 2.3.1.234 O Glycoprotease family
ALFGKDHI_01633 1.7e-119 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
ALFGKDHI_01634 4.8e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
ALFGKDHI_01635 0.0 comE S Competence protein
ALFGKDHI_01636 1.5e-91 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
ALFGKDHI_01637 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
ALFGKDHI_01638 2.7e-166 ET Bacterial periplasmic substrate-binding proteins
ALFGKDHI_01639 3.7e-171 corA P CorA-like Mg2+ transporter protein
ALFGKDHI_01640 1.8e-161 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
ALFGKDHI_01641 1.2e-299 E Serine carboxypeptidase
ALFGKDHI_01642 0.0 S Psort location Cytoplasmic, score 8.87
ALFGKDHI_01643 1.2e-111 S Domain of unknown function (DUF4194)
ALFGKDHI_01644 8.2e-282 S Psort location Cytoplasmic, score 8.87
ALFGKDHI_01645 2.4e-161 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ALFGKDHI_01646 1.7e-63 yeaO K Protein of unknown function, DUF488
ALFGKDHI_01647 5.4e-118 ydaF_1 J Acetyltransferase (GNAT) domain
ALFGKDHI_01648 8.3e-90 MA20_25245 K FR47-like protein
ALFGKDHI_01649 7.9e-55 K Transcriptional regulator
ALFGKDHI_01650 1.3e-100 XK27_07525 3.6.1.55 F Hydrolase of X-linked nucleoside diphosphate N terminal
ALFGKDHI_01652 1.7e-184 S Acetyltransferase (GNAT) domain
ALFGKDHI_01653 7.4e-22 qseC 2.7.13.3 T Histidine kinase
ALFGKDHI_01654 8.5e-133 S SOS response associated peptidase (SRAP)
ALFGKDHI_01655 3.6e-131
ALFGKDHI_01656 2.5e-80 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ALFGKDHI_01657 3.4e-164 rpoC M heme binding
ALFGKDHI_01658 1.3e-45 EGP Major facilitator Superfamily
ALFGKDHI_01660 6.3e-157
ALFGKDHI_01661 3.1e-11 CE Amino acid permease
ALFGKDHI_01662 5e-96 ypjC S Putative ABC-transporter type IV
ALFGKDHI_01663 2.3e-110 ycaK 1.6.5.2 S NADPH-dependent FMN reductase
ALFGKDHI_01664 6.3e-193 V VanZ like family
ALFGKDHI_01665 3.2e-147 KT RESPONSE REGULATOR receiver
ALFGKDHI_01666 3.5e-70 pdxH S Pfam:Pyridox_oxidase
ALFGKDHI_01667 1.1e-140 yijF S Domain of unknown function (DUF1287)
ALFGKDHI_01668 1.1e-132 C Putative TM nitroreductase
ALFGKDHI_01669 2.3e-101
ALFGKDHI_01671 9.3e-255 nplT 3.2.1.1 GH13 G Alpha amylase, catalytic domain
ALFGKDHI_01672 1.3e-78 S Bacterial PH domain
ALFGKDHI_01673 4.2e-138 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
ALFGKDHI_01674 1.2e-68 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
ALFGKDHI_01675 1.3e-262 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ALFGKDHI_01677 9.1e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ALFGKDHI_01678 8.1e-145 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ALFGKDHI_01679 4.4e-92
ALFGKDHI_01680 2.6e-236 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ALFGKDHI_01681 1.5e-283 thrC 4.2.3.1 E Threonine synthase N terminus
ALFGKDHI_01682 4.5e-121 S ABC-2 family transporter protein
ALFGKDHI_01683 1.2e-124 S ABC-2 family transporter protein
ALFGKDHI_01684 2.7e-177 V ATPases associated with a variety of cellular activities
ALFGKDHI_01685 3.7e-58 K helix_turn_helix gluconate operon transcriptional repressor
ALFGKDHI_01686 3.4e-123 S Haloacid dehalogenase-like hydrolase
ALFGKDHI_01687 2.9e-294 recN L May be involved in recombinational repair of damaged DNA
ALFGKDHI_01688 7.3e-183 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ALFGKDHI_01689 3.9e-236 trkB P Cation transport protein
ALFGKDHI_01690 6.8e-116 trkA P TrkA-N domain
ALFGKDHI_01691 1e-103
ALFGKDHI_01692 3.6e-137 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
ALFGKDHI_01694 2.3e-190 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
ALFGKDHI_01695 4e-159 L Tetratricopeptide repeat
ALFGKDHI_01696 3.7e-254 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ALFGKDHI_01697 1.6e-143 S Putative ABC-transporter type IV
ALFGKDHI_01698 2.7e-108 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
ALFGKDHI_01699 1.4e-281 argH 4.3.2.1 E argininosuccinate lyase
ALFGKDHI_01700 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
ALFGKDHI_01701 8.9e-279 3.6.4.12 K Putative DNA-binding domain
ALFGKDHI_01702 8.6e-58 3.1.21.3 V Type I restriction
ALFGKDHI_01703 0.0 hsdM 2.1.1.72 V modification (methylase) protein of type I restriction-modification system K03427
ALFGKDHI_01704 1.9e-155 S Domain of unknown function (DUF4357)
ALFGKDHI_01705 2.4e-30
ALFGKDHI_01706 4e-178 L Phage integrase family
ALFGKDHI_01707 4.1e-239 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
ALFGKDHI_01708 1.1e-84 argR K Regulates arginine biosynthesis genes
ALFGKDHI_01709 1.6e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ALFGKDHI_01710 1.9e-247 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
ALFGKDHI_01711 1.7e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
ALFGKDHI_01712 1.3e-215 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ALFGKDHI_01713 1.1e-203 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ALFGKDHI_01714 5.6e-86
ALFGKDHI_01715 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
ALFGKDHI_01716 3.1e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ALFGKDHI_01717 7e-161 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ALFGKDHI_01718 2.6e-135 ybbL V ATPases associated with a variety of cellular activities
ALFGKDHI_01719 2.7e-135 ybbM V Uncharacterised protein family (UPF0014)
ALFGKDHI_01720 1.2e-28 IQ oxidoreductase activity
ALFGKDHI_01722 8.9e-93 K AraC-like ligand binding domain
ALFGKDHI_01723 1.4e-237 rutG F Permease family
ALFGKDHI_01724 1.1e-158 3.1.3.73 G Phosphoglycerate mutase family
ALFGKDHI_01725 2.7e-62 S Phospholipase/Carboxylesterase
ALFGKDHI_01726 1.4e-187 MA20_14895 S Conserved hypothetical protein 698
ALFGKDHI_01727 8.7e-145 rlrG K Bacterial regulatory helix-turn-helix protein, lysR family
ALFGKDHI_01728 3.9e-116 3.1.3.27 E haloacid dehalogenase-like hydrolase
ALFGKDHI_01729 1.9e-289 2.4.1.166 GT2 M Glycosyltransferase like family 2
ALFGKDHI_01731 0.0 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
ALFGKDHI_01732 2.1e-125 ypfH S Phospholipase/Carboxylesterase
ALFGKDHI_01733 2.7e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
ALFGKDHI_01734 9.7e-24
ALFGKDHI_01735 1.2e-34 yhcC S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
ALFGKDHI_01736 2.8e-66 S Zincin-like metallopeptidase
ALFGKDHI_01737 8.2e-91 S Helix-turn-helix
ALFGKDHI_01738 2.3e-182 S Short C-terminal domain
ALFGKDHI_01739 2.7e-22
ALFGKDHI_01740 3.1e-149
ALFGKDHI_01741 7.7e-25 K Psort location Cytoplasmic, score
ALFGKDHI_01742 1.1e-43 K Psort location Cytoplasmic, score
ALFGKDHI_01743 1.4e-258 KLT Protein tyrosine kinase
ALFGKDHI_01744 2.9e-59 S Cupin 2, conserved barrel domain protein
ALFGKDHI_01745 1.5e-155 ksgA 2.1.1.182 J Methyltransferase domain
ALFGKDHI_01746 5.6e-59 yccF S Inner membrane component domain
ALFGKDHI_01747 6e-121 E Psort location Cytoplasmic, score 8.87
ALFGKDHI_01748 3e-39 L Psort location Cytoplasmic, score 8.87
ALFGKDHI_01749 6.9e-123 L Integrase core domain
ALFGKDHI_01750 4.6e-16
ALFGKDHI_01753 3.4e-09
ALFGKDHI_01754 2.4e-60 S competence protein
ALFGKDHI_01755 7.6e-31 dprA LU DNA recombination-mediator protein A
ALFGKDHI_01756 6.8e-08 int L Phage integrase, N-terminal SAM-like domain
ALFGKDHI_01757 9.7e-30
ALFGKDHI_01758 5e-27 S Protein of unknown function (DUF3800)
ALFGKDHI_01759 1.8e-194 int L Phage integrase, N-terminal SAM-like domain
ALFGKDHI_01760 1.4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
ALFGKDHI_01761 1.7e-229 mtnE 2.6.1.83 E Aminotransferase class I and II
ALFGKDHI_01762 2.9e-93 metI P Binding-protein-dependent transport system inner membrane component
ALFGKDHI_01763 3e-204 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ALFGKDHI_01764 1.7e-182 1.2.4.1 C Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
ALFGKDHI_01765 1.7e-187 acoA 1.2.4.1 C Dehydrogenase E1 component
ALFGKDHI_01766 9.3e-147 P NLPA lipoprotein
ALFGKDHI_01767 6.4e-168 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
ALFGKDHI_01768 4.7e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ALFGKDHI_01769 2.7e-263 pip 3.4.11.5 S alpha/beta hydrolase fold
ALFGKDHI_01770 0.0 tcsS2 T Histidine kinase
ALFGKDHI_01771 4e-29 K helix_turn_helix, Lux Regulon
ALFGKDHI_01772 4.2e-17 phoN I PAP2 superfamily
ALFGKDHI_01773 6.7e-142 phoN I PAP2 superfamily
ALFGKDHI_01774 7.8e-219 phoN I PAP2 superfamily
ALFGKDHI_01775 2.6e-252 metY 2.5.1.49 E Aminotransferase class-V
ALFGKDHI_01776 7.9e-157 S Putative ABC-transporter type IV
ALFGKDHI_01777 1.5e-166 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
ALFGKDHI_01778 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
ALFGKDHI_01779 6.5e-57 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
ALFGKDHI_01780 1.4e-281 dprA 5.99.1.2 LU DNA recombination-mediator protein A
ALFGKDHI_01781 1.9e-294 comM O Magnesium chelatase, subunit ChlI C-terminal
ALFGKDHI_01782 1.3e-73 yraN L Belongs to the UPF0102 family
ALFGKDHI_01783 3e-184 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
ALFGKDHI_01784 2.2e-117 safC S O-methyltransferase
ALFGKDHI_01785 7.1e-167 fmt2 3.2.2.10 S Belongs to the LOG family
ALFGKDHI_01786 2e-225 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ALFGKDHI_01787 1.7e-234 patB 4.4.1.8 E Aminotransferase, class I II
ALFGKDHI_01790 7.7e-244 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ALFGKDHI_01791 1.5e-127 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
ALFGKDHI_01792 1.1e-112 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
ALFGKDHI_01793 5.7e-253 clcA_2 P Voltage gated chloride channel
ALFGKDHI_01794 2.8e-236 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
ALFGKDHI_01795 2.4e-250 rnd 3.1.13.5 J 3'-5' exonuclease
ALFGKDHI_01796 4.4e-114 S Protein of unknown function (DUF3000)
ALFGKDHI_01797 3.9e-175 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)