ORF_ID e_value Gene_name EC_number CAZy COGs Description
BHKMAKMB_00004 7.8e-08
BHKMAKMB_00012 2e-08
BHKMAKMB_00016 2.7e-143 spo0M S COG4326 Sporulation control protein
BHKMAKMB_00017 3e-27
BHKMAKMB_00018 5.9e-134 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
BHKMAKMB_00019 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BHKMAKMB_00020 1.9e-266 ygaK C Berberine and berberine like
BHKMAKMB_00022 3.2e-291 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
BHKMAKMB_00023 1.1e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
BHKMAKMB_00024 1.7e-171 ssuA M Sulfonate ABC transporter
BHKMAKMB_00025 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
BHKMAKMB_00026 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
BHKMAKMB_00028 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BHKMAKMB_00029 4.1e-78 ygaO
BHKMAKMB_00030 4.4e-29 K Transcriptional regulator
BHKMAKMB_00032 7.9e-114 yhzB S B3/4 domain
BHKMAKMB_00033 2.1e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BHKMAKMB_00034 4.4e-177 yhbB S Putative amidase domain
BHKMAKMB_00035 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
BHKMAKMB_00036 1.2e-109 yhbD K Protein of unknown function (DUF4004)
BHKMAKMB_00037 1.6e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
BHKMAKMB_00038 8.2e-75 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
BHKMAKMB_00039 0.0 prkA T Ser protein kinase
BHKMAKMB_00040 2.5e-225 yhbH S Belongs to the UPF0229 family
BHKMAKMB_00041 2.2e-76 yhbI K DNA-binding transcription factor activity
BHKMAKMB_00042 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
BHKMAKMB_00043 3.1e-271 yhcA EGP Major facilitator Superfamily
BHKMAKMB_00044 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
BHKMAKMB_00045 2.8e-37 yhcC
BHKMAKMB_00046 7.8e-55
BHKMAKMB_00047 6.6e-60 yhcF K Transcriptional regulator
BHKMAKMB_00048 1.6e-123 yhcG V ABC transporter, ATP-binding protein
BHKMAKMB_00049 2.6e-166 yhcH V ABC transporter, ATP-binding protein
BHKMAKMB_00050 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
BHKMAKMB_00051 1e-30 cspB K Cold-shock protein
BHKMAKMB_00052 5.2e-153 metQ M Belongs to the nlpA lipoprotein family
BHKMAKMB_00053 1.2e-197 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
BHKMAKMB_00054 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
BHKMAKMB_00055 3.7e-44 yhcM
BHKMAKMB_00056 2.1e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
BHKMAKMB_00057 2.5e-167 yhcP
BHKMAKMB_00058 5.2e-100 yhcQ M Spore coat protein
BHKMAKMB_00059 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
BHKMAKMB_00060 7.6e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
BHKMAKMB_00061 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
BHKMAKMB_00062 9.3e-68 yhcU S Family of unknown function (DUF5365)
BHKMAKMB_00063 9.9e-68 yhcV S COG0517 FOG CBS domain
BHKMAKMB_00064 4.6e-120 yhcW 5.4.2.6 S hydrolase
BHKMAKMB_00065 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
BHKMAKMB_00066 1.1e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BHKMAKMB_00067 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BHKMAKMB_00068 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
BHKMAKMB_00069 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BHKMAKMB_00070 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BHKMAKMB_00071 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
BHKMAKMB_00072 5.5e-214 yhcY 2.7.13.3 T Histidine kinase
BHKMAKMB_00073 1.1e-113 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
BHKMAKMB_00074 1.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
BHKMAKMB_00075 1.2e-38 yhdB S YhdB-like protein
BHKMAKMB_00076 4.8e-54 yhdC S Protein of unknown function (DUF3889)
BHKMAKMB_00077 7.9e-189 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
BHKMAKMB_00078 3.5e-76 nsrR K Transcriptional regulator
BHKMAKMB_00079 8.7e-239 ygxB M Conserved TM helix
BHKMAKMB_00080 2.1e-276 ycgB S Stage V sporulation protein R
BHKMAKMB_00081 5.8e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
BHKMAKMB_00082 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
BHKMAKMB_00083 3.8e-162 citR K Transcriptional regulator
BHKMAKMB_00084 1.4e-206 citA 2.3.3.1 C Belongs to the citrate synthase family
BHKMAKMB_00085 4.9e-162 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
BHKMAKMB_00086 3.4e-250 yhdG E amino acid
BHKMAKMB_00087 1.5e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
BHKMAKMB_00088 3.7e-276 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
BHKMAKMB_00089 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
BHKMAKMB_00090 8.1e-45 yhdK S Sigma-M inhibitor protein
BHKMAKMB_00091 6.6e-201 yhdL S Sigma factor regulator N-terminal
BHKMAKMB_00092 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
BHKMAKMB_00093 1.5e-191 yhdN C Aldo keto reductase
BHKMAKMB_00094 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
BHKMAKMB_00095 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
BHKMAKMB_00096 4.1e-74 cueR K transcriptional
BHKMAKMB_00097 1.4e-223 yhdR 2.6.1.1 E Aminotransferase
BHKMAKMB_00098 1.1e-240 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
BHKMAKMB_00099 2.8e-47 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BHKMAKMB_00100 5.1e-66 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BHKMAKMB_00101 3.3e-135 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
BHKMAKMB_00103 6.6e-204 yhdY M Mechanosensitive ion channel
BHKMAKMB_00104 1.2e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
BHKMAKMB_00105 1.7e-151 yheN G deacetylase
BHKMAKMB_00106 1.1e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
BHKMAKMB_00107 2.2e-233 nhaC C Na H antiporter
BHKMAKMB_00108 3.1e-84 nhaX T Belongs to the universal stress protein A family
BHKMAKMB_00109 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
BHKMAKMB_00110 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
BHKMAKMB_00111 3.7e-111 yheG GM NAD(P)H-binding
BHKMAKMB_00112 6.3e-28 sspB S spore protein
BHKMAKMB_00113 1.3e-36 yheE S Family of unknown function (DUF5342)
BHKMAKMB_00114 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
BHKMAKMB_00115 4.3e-216 yheC HJ YheC/D like ATP-grasp
BHKMAKMB_00116 6.7e-204 yheB S Belongs to the UPF0754 family
BHKMAKMB_00117 9.5e-48 yheA S Belongs to the UPF0342 family
BHKMAKMB_00118 3.1e-206 yhaZ L DNA alkylation repair enzyme
BHKMAKMB_00119 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
BHKMAKMB_00120 7.1e-294 hemZ H coproporphyrinogen III oxidase
BHKMAKMB_00121 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
BHKMAKMB_00122 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
BHKMAKMB_00124 1.9e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
BHKMAKMB_00125 1.1e-26 S YhzD-like protein
BHKMAKMB_00126 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
BHKMAKMB_00127 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
BHKMAKMB_00128 3.6e-227 yhaO L DNA repair exonuclease
BHKMAKMB_00129 0.0 yhaN L AAA domain
BHKMAKMB_00130 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
BHKMAKMB_00131 1.6e-21 yhaL S Sporulation protein YhaL
BHKMAKMB_00132 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
BHKMAKMB_00133 8.7e-90 yhaK S Putative zincin peptidase
BHKMAKMB_00134 1.3e-54 yhaI S Protein of unknown function (DUF1878)
BHKMAKMB_00135 1e-113 hpr K Negative regulator of protease production and sporulation
BHKMAKMB_00136 7e-39 yhaH S YtxH-like protein
BHKMAKMB_00137 3.6e-80 trpP S Tryptophan transporter TrpP
BHKMAKMB_00138 9.9e-205 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BHKMAKMB_00139 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
BHKMAKMB_00140 4.6e-137 ecsA V transporter (ATP-binding protein)
BHKMAKMB_00141 1.8e-215 ecsB U ABC transporter
BHKMAKMB_00142 4.8e-115 ecsC S EcsC protein family
BHKMAKMB_00143 2.3e-231 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
BHKMAKMB_00144 4.2e-248 yhfA C membrane
BHKMAKMB_00145 5.4e-10 1.15.1.2 C Rubrerythrin
BHKMAKMB_00146 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
BHKMAKMB_00147 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
BHKMAKMB_00148 1.7e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BHKMAKMB_00149 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
BHKMAKMB_00150 1.7e-268 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BHKMAKMB_00151 1.4e-101 yhgD K Transcriptional regulator
BHKMAKMB_00152 1e-238 yhgE S YhgE Pip N-terminal domain protein
BHKMAKMB_00153 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BHKMAKMB_00154 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
BHKMAKMB_00155 1.6e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
BHKMAKMB_00156 1.7e-72 3.4.13.21 S ASCH
BHKMAKMB_00157 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
BHKMAKMB_00158 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
BHKMAKMB_00159 2e-191 lplJ 6.3.1.20 H Lipoate-protein ligase
BHKMAKMB_00160 2.6e-112 yhfK GM NmrA-like family
BHKMAKMB_00161 7.3e-302 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
BHKMAKMB_00162 1.9e-65 yhfM
BHKMAKMB_00163 5.4e-242 yhfN 3.4.24.84 O Peptidase M48
BHKMAKMB_00164 2.3e-204 aprE 3.4.21.62 O Belongs to the peptidase S8 family
BHKMAKMB_00165 9.2e-80 VY92_01935 K acetyltransferase
BHKMAKMB_00166 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
BHKMAKMB_00167 4.3e-159 yfmC M Periplasmic binding protein
BHKMAKMB_00168 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
BHKMAKMB_00169 2.3e-201 vraB 2.3.1.9 I Belongs to the thiolase family
BHKMAKMB_00170 1e-281 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
BHKMAKMB_00171 5e-91 bioY S BioY family
BHKMAKMB_00172 1.7e-182 hemAT NT chemotaxis protein
BHKMAKMB_00173 1.1e-302 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
BHKMAKMB_00174 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
BHKMAKMB_00175 1.3e-32 yhzC S IDEAL
BHKMAKMB_00176 4.2e-109 comK K Competence transcription factor
BHKMAKMB_00177 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
BHKMAKMB_00178 7.8e-42 yhjA S Excalibur calcium-binding domain
BHKMAKMB_00179 6.1e-266 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BHKMAKMB_00180 6.9e-27 yhjC S Protein of unknown function (DUF3311)
BHKMAKMB_00181 5e-60 yhjD
BHKMAKMB_00182 9.1e-110 yhjE S SNARE associated Golgi protein
BHKMAKMB_00183 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
BHKMAKMB_00184 1.1e-286 yhjG CH FAD binding domain
BHKMAKMB_00185 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
BHKMAKMB_00186 6.9e-215 glcP G Major Facilitator Superfamily
BHKMAKMB_00187 1.1e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
BHKMAKMB_00188 1.8e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
BHKMAKMB_00189 4.4e-255 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
BHKMAKMB_00190 7e-189 yhjM 5.1.1.1 K Transcriptional regulator
BHKMAKMB_00191 3.8e-202 abrB S membrane
BHKMAKMB_00192 3.1e-215 EGP Transmembrane secretion effector
BHKMAKMB_00193 0.0 S Sugar transport-related sRNA regulator N-term
BHKMAKMB_00194 2e-36 yhjQ C COG1145 Ferredoxin
BHKMAKMB_00195 2.2e-78 yhjR S Rubrerythrin
BHKMAKMB_00196 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
BHKMAKMB_00197 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
BHKMAKMB_00198 1.7e-221 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
BHKMAKMB_00199 0.0 sbcC L COG0419 ATPase involved in DNA repair
BHKMAKMB_00200 6e-51 yisB V COG1403 Restriction endonuclease
BHKMAKMB_00201 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
BHKMAKMB_00202 3e-66 gerPE S Spore germination protein GerPE
BHKMAKMB_00203 6.3e-24 gerPD S Spore germination protein
BHKMAKMB_00204 1.8e-54 gerPC S Spore germination protein
BHKMAKMB_00205 4e-34 gerPB S cell differentiation
BHKMAKMB_00206 1.9e-33 gerPA S Spore germination protein
BHKMAKMB_00207 1.5e-22 yisI S Spo0E like sporulation regulatory protein
BHKMAKMB_00208 1.7e-176 cotH M Spore Coat
BHKMAKMB_00209 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
BHKMAKMB_00210 3e-57 yisL S UPF0344 protein
BHKMAKMB_00211 0.0 wprA O Belongs to the peptidase S8 family
BHKMAKMB_00212 7.2e-106 yisN S Protein of unknown function (DUF2777)
BHKMAKMB_00213 0.0 asnO 6.3.5.4 E Asparagine synthase
BHKMAKMB_00214 2.1e-88 yizA S Damage-inducible protein DinB
BHKMAKMB_00215 6.8e-150 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
BHKMAKMB_00216 4e-243 yisQ V Mate efflux family protein
BHKMAKMB_00217 1.4e-161 yisR K Transcriptional regulator
BHKMAKMB_00218 2.4e-184 purR K helix_turn _helix lactose operon repressor
BHKMAKMB_00219 4.5e-199 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
BHKMAKMB_00220 1.3e-93 yisT S DinB family
BHKMAKMB_00221 6.4e-108 argO S Lysine exporter protein LysE YggA
BHKMAKMB_00222 1.7e-281 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
BHKMAKMB_00223 4e-36 mcbG S Pentapeptide repeats (9 copies)
BHKMAKMB_00224 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
BHKMAKMB_00225 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
BHKMAKMB_00226 3.2e-233 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
BHKMAKMB_00227 9.2e-143 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
BHKMAKMB_00228 4.9e-125 comB 3.1.3.71 H Belongs to the ComB family
BHKMAKMB_00229 1.9e-141 yitD 4.4.1.19 S synthase
BHKMAKMB_00230 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
BHKMAKMB_00231 5.4e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
BHKMAKMB_00232 4e-229 yitG EGP Major facilitator Superfamily
BHKMAKMB_00233 1.8e-161 yitH K Acetyltransferase (GNAT) domain
BHKMAKMB_00234 2e-82 yjcF S Acetyltransferase (GNAT) domain
BHKMAKMB_00235 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
BHKMAKMB_00236 1.2e-53 yajQ S Belongs to the UPF0234 family
BHKMAKMB_00237 4e-161 cvfB S protein conserved in bacteria
BHKMAKMB_00238 8.5e-94
BHKMAKMB_00239 2.8e-171
BHKMAKMB_00240 1.5e-97 S Sporulation delaying protein SdpA
BHKMAKMB_00241 1.5e-58 K Transcriptional regulator PadR-like family
BHKMAKMB_00242 2e-95
BHKMAKMB_00243 1.4e-44 yitR S Domain of unknown function (DUF3784)
BHKMAKMB_00244 2.2e-311 nprB 3.4.24.28 E Peptidase M4
BHKMAKMB_00245 8.4e-159 yitS S protein conserved in bacteria
BHKMAKMB_00246 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
BHKMAKMB_00247 1.9e-72 ipi S Intracellular proteinase inhibitor
BHKMAKMB_00248 1.2e-17 S Protein of unknown function (DUF3813)
BHKMAKMB_00249 1.9e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
BHKMAKMB_00250 4.5e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
BHKMAKMB_00251 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
BHKMAKMB_00252 1.5e-22 pilT S Proteolipid membrane potential modulator
BHKMAKMB_00253 4.3e-272 yitY C D-arabinono-1,4-lactone oxidase
BHKMAKMB_00254 1.7e-88 norB G Major Facilitator Superfamily
BHKMAKMB_00255 5.4e-200 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BHKMAKMB_00256 3.1e-231 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BHKMAKMB_00257 2.2e-137 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
BHKMAKMB_00258 4.4e-219 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
BHKMAKMB_00259 3.9e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
BHKMAKMB_00260 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
BHKMAKMB_00261 3.8e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BHKMAKMB_00262 9.5e-28 yjzC S YjzC-like protein
BHKMAKMB_00263 2.3e-16 yjzD S Protein of unknown function (DUF2929)
BHKMAKMB_00264 6.2e-142 yjaU I carboxylic ester hydrolase activity
BHKMAKMB_00265 7.3e-103 yjaV
BHKMAKMB_00266 1.1e-183 med S Transcriptional activator protein med
BHKMAKMB_00267 7.3e-26 comZ S ComZ
BHKMAKMB_00268 2.7e-22 yjzB
BHKMAKMB_00269 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BHKMAKMB_00270 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
BHKMAKMB_00271 7.8e-151 yjaZ O Zn-dependent protease
BHKMAKMB_00272 1.8e-184 appD P Belongs to the ABC transporter superfamily
BHKMAKMB_00273 6.5e-187 appF E Belongs to the ABC transporter superfamily
BHKMAKMB_00274 3.5e-48 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
BHKMAKMB_00275 1.9e-190 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
BHKMAKMB_00276 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
BHKMAKMB_00277 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
BHKMAKMB_00278 5e-147 yjbA S Belongs to the UPF0736 family
BHKMAKMB_00279 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
BHKMAKMB_00280 0.0 oppA E ABC transporter substrate-binding protein
BHKMAKMB_00281 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
BHKMAKMB_00282 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
BHKMAKMB_00283 3e-198 oppD P Belongs to the ABC transporter superfamily
BHKMAKMB_00284 5.5e-172 oppF E Belongs to the ABC transporter superfamily
BHKMAKMB_00285 8.6e-196 yjbB EGP Major Facilitator Superfamily
BHKMAKMB_00286 6.9e-104 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
BHKMAKMB_00287 2.1e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
BHKMAKMB_00288 6e-112 yjbE P Integral membrane protein TerC family
BHKMAKMB_00289 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
BHKMAKMB_00290 2.3e-223 yjbF S Competence protein
BHKMAKMB_00291 0.0 pepF E oligoendopeptidase F
BHKMAKMB_00292 1.8e-20
BHKMAKMB_00294 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
BHKMAKMB_00295 3.7e-72 yjbI S Bacterial-like globin
BHKMAKMB_00296 1.5e-87 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
BHKMAKMB_00297 2.4e-101 yjbK S protein conserved in bacteria
BHKMAKMB_00298 7.1e-62 yjbL S Belongs to the UPF0738 family
BHKMAKMB_00299 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
BHKMAKMB_00300 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BHKMAKMB_00301 9.5e-161 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
BHKMAKMB_00302 3e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
BHKMAKMB_00303 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
BHKMAKMB_00304 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BHKMAKMB_00305 3.8e-108 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
BHKMAKMB_00306 7.2e-219 thiO 1.4.3.19 E Glycine oxidase
BHKMAKMB_00307 3e-30 thiS H thiamine diphosphate biosynthetic process
BHKMAKMB_00308 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
BHKMAKMB_00309 6e-188 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
BHKMAKMB_00310 5.3e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
BHKMAKMB_00311 9.5e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
BHKMAKMB_00312 5.9e-54 yjbX S Spore coat protein
BHKMAKMB_00313 5.2e-83 cotZ S Spore coat protein
BHKMAKMB_00314 3.4e-96 cotY S Spore coat protein Z
BHKMAKMB_00315 6.4e-77 cotX S Spore Coat Protein X and V domain
BHKMAKMB_00316 3e-32 cotW
BHKMAKMB_00317 2.3e-55 cotV S Spore Coat Protein X and V domain
BHKMAKMB_00318 8.7e-57 yjcA S Protein of unknown function (DUF1360)
BHKMAKMB_00321 2.9e-38 spoVIF S Stage VI sporulation protein F
BHKMAKMB_00322 0.0 yjcD 3.6.4.12 L DNA helicase
BHKMAKMB_00323 1.7e-38
BHKMAKMB_00324 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
BHKMAKMB_00325 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
BHKMAKMB_00326 1.8e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
BHKMAKMB_00327 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
BHKMAKMB_00328 6.5e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
BHKMAKMB_00329 3.7e-99 rimJ 2.3.1.128 J Alanine acetyltransferase
BHKMAKMB_00330 1.1e-212 yjcL S Protein of unknown function (DUF819)
BHKMAKMB_00333 3.9e-189 S Putative amidase domain
BHKMAKMB_00334 2.6e-44 yjcN
BHKMAKMB_00337 8.5e-81 L Transposase
BHKMAKMB_00338 1.6e-72 yjcP
BHKMAKMB_00339 4.1e-49 S YjcQ protein
BHKMAKMB_00340 1.1e-92 yqaS L DNA packaging
BHKMAKMB_00341 2.2e-47 yjcS S Antibiotic biosynthesis monooxygenase
BHKMAKMB_00342 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
BHKMAKMB_00344 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
BHKMAKMB_00345 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
BHKMAKMB_00346 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
BHKMAKMB_00347 4.8e-51 yjdF S Protein of unknown function (DUF2992)
BHKMAKMB_00348 2.5e-94 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
BHKMAKMB_00350 8e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BHKMAKMB_00351 4.2e-29 S Domain of unknown function (DUF4177)
BHKMAKMB_00352 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
BHKMAKMB_00353 3.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
BHKMAKMB_00355 1.4e-264 xynD 3.5.1.104 G Polysaccharide deacetylase
BHKMAKMB_00356 5.5e-83 S Protein of unknown function (DUF2690)
BHKMAKMB_00357 3.6e-21 yjfB S Putative motility protein
BHKMAKMB_00358 1.6e-171 yjfC O Predicted Zn-dependent protease (DUF2268)
BHKMAKMB_00359 1.2e-45 T PhoQ Sensor
BHKMAKMB_00360 8.9e-104 yjgB S Domain of unknown function (DUF4309)
BHKMAKMB_00361 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
BHKMAKMB_00362 1.3e-94 yjgD S Protein of unknown function (DUF1641)
BHKMAKMB_00363 8.7e-07 S Domain of unknown function (DUF4352)
BHKMAKMB_00364 2e-117 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
BHKMAKMB_00366 3.8e-226 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
BHKMAKMB_00367 4.5e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
BHKMAKMB_00368 8.2e-30
BHKMAKMB_00369 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
BHKMAKMB_00370 1.9e-122 ybbM S transport system, permease component
BHKMAKMB_00371 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
BHKMAKMB_00372 1.8e-176 yjlA EG Putative multidrug resistance efflux transporter
BHKMAKMB_00373 2.8e-93 yjlB S Cupin domain
BHKMAKMB_00374 7.1e-66 yjlC S Protein of unknown function (DUF1641)
BHKMAKMB_00375 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
BHKMAKMB_00376 6.3e-284 uxaC 5.3.1.12 G glucuronate isomerase
BHKMAKMB_00377 5.8e-250 yjmB G symporter YjmB
BHKMAKMB_00378 3e-195 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
BHKMAKMB_00379 1.6e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
BHKMAKMB_00380 4.7e-215 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
BHKMAKMB_00381 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
BHKMAKMB_00382 3.7e-227 exuT G Sugar (and other) transporter
BHKMAKMB_00383 2.3e-184 exuR K transcriptional
BHKMAKMB_00384 2.1e-287 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
BHKMAKMB_00385 2e-288 uxaA 4.2.1.7, 4.4.1.24 G Altronate
BHKMAKMB_00386 4.3e-130 MA20_18170 S membrane transporter protein
BHKMAKMB_00387 3.3e-80 yjoA S DinB family
BHKMAKMB_00388 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
BHKMAKMB_00389 2.1e-213 S response regulator aspartate phosphatase
BHKMAKMB_00391 6.3e-41 S YCII-related domain
BHKMAKMB_00392 9.1e-170 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
BHKMAKMB_00393 2.1e-61 yjqA S Bacterial PH domain
BHKMAKMB_00394 4.2e-112 yjqB S Pfam:DUF867
BHKMAKMB_00395 4.4e-160 ydbD P Catalase
BHKMAKMB_00396 1.6e-111 xkdA E IrrE N-terminal-like domain
BHKMAKMB_00397 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
BHKMAKMB_00399 5.9e-157 xkdB K sequence-specific DNA binding
BHKMAKMB_00400 6.4e-119 xkdC L Bacterial dnaA protein
BHKMAKMB_00403 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
BHKMAKMB_00404 4.4e-86 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
BHKMAKMB_00405 4.8e-140 xtmA L phage terminase small subunit
BHKMAKMB_00406 9.6e-255 xtmB S phage terminase, large subunit
BHKMAKMB_00407 5.4e-286 yqbA S portal protein
BHKMAKMB_00408 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
BHKMAKMB_00409 5.8e-169 xkdG S Phage capsid family
BHKMAKMB_00410 5.5e-65 yqbG S Protein of unknown function (DUF3199)
BHKMAKMB_00411 8.7e-65 yqbH S Domain of unknown function (DUF3599)
BHKMAKMB_00412 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
BHKMAKMB_00413 1.9e-77 xkdJ
BHKMAKMB_00414 2.5e-256 xkdK S Phage tail sheath C-terminal domain
BHKMAKMB_00415 6.1e-76 xkdM S Phage tail tube protein
BHKMAKMB_00416 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
BHKMAKMB_00417 0.0 xkdO L Transglycosylase SLT domain
BHKMAKMB_00418 3.7e-122 xkdP S Lysin motif
BHKMAKMB_00419 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
BHKMAKMB_00420 2.1e-39 xkdR S Protein of unknown function (DUF2577)
BHKMAKMB_00421 9.6e-71 xkdS S Protein of unknown function (DUF2634)
BHKMAKMB_00422 1.2e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
BHKMAKMB_00423 4e-104 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
BHKMAKMB_00424 6.7e-41
BHKMAKMB_00425 0.0
BHKMAKMB_00426 2.6e-55 xkdW S XkdW protein
BHKMAKMB_00427 1.7e-23 xkdX
BHKMAKMB_00428 1.2e-154 xepA
BHKMAKMB_00429 2.8e-39 xhlA S Haemolysin XhlA
BHKMAKMB_00430 9.3e-40 xhlB S SPP1 phage holin
BHKMAKMB_00431 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
BHKMAKMB_00432 6.7e-23 spoIISB S Stage II sporulation protein SB
BHKMAKMB_00433 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
BHKMAKMB_00434 5.8e-175 pit P phosphate transporter
BHKMAKMB_00435 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
BHKMAKMB_00436 9.4e-242 steT E amino acid
BHKMAKMB_00437 7.2e-183 mhqA E COG0346 Lactoylglutathione lyase and related lyases
BHKMAKMB_00439 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BHKMAKMB_00440 1.3e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
BHKMAKMB_00442 8.5e-214 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BHKMAKMB_00443 1e-137 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
BHKMAKMB_00444 7.9e-154 dppA E D-aminopeptidase
BHKMAKMB_00445 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
BHKMAKMB_00446 3.9e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
BHKMAKMB_00447 3.4e-191 dppD P Belongs to the ABC transporter superfamily
BHKMAKMB_00448 0.0 dppE E ABC transporter substrate-binding protein
BHKMAKMB_00450 8.1e-179 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
BHKMAKMB_00451 3.2e-203 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
BHKMAKMB_00452 5.3e-172 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
BHKMAKMB_00453 7.7e-188 ykfD E Belongs to the ABC transporter superfamily
BHKMAKMB_00454 7.4e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
BHKMAKMB_00455 5.3e-161 ykgA E Amidinotransferase
BHKMAKMB_00456 1.5e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
BHKMAKMB_00457 1e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BHKMAKMB_00458 1e-07
BHKMAKMB_00459 5.4e-130 ykjA S Protein of unknown function (DUF421)
BHKMAKMB_00460 1e-98 ykkA S Protein of unknown function (DUF664)
BHKMAKMB_00461 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
BHKMAKMB_00462 3.5e-55 ykkC P Multidrug resistance protein
BHKMAKMB_00463 1.1e-50 ykkD P Multidrug resistance protein
BHKMAKMB_00464 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
BHKMAKMB_00465 1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BHKMAKMB_00466 2.5e-228 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BHKMAKMB_00467 1.3e-70 ohrA O Organic hydroperoxide resistance protein
BHKMAKMB_00468 3.9e-75 ohrR K COG1846 Transcriptional regulators
BHKMAKMB_00469 8.4e-72 ohrB O Organic hydroperoxide resistance protein
BHKMAKMB_00471 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
BHKMAKMB_00472 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BHKMAKMB_00473 1.7e-176 isp O Belongs to the peptidase S8 family
BHKMAKMB_00474 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
BHKMAKMB_00475 1.8e-136 ykoC P Cobalt transport protein
BHKMAKMB_00476 4.6e-311 P ABC transporter, ATP-binding protein
BHKMAKMB_00477 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
BHKMAKMB_00478 7.9e-111 ykoF S YKOF-related Family
BHKMAKMB_00479 2.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BHKMAKMB_00480 9.4e-245 ykoH 2.7.13.3 T Histidine kinase
BHKMAKMB_00481 1.1e-113 ykoI S Peptidase propeptide and YPEB domain
BHKMAKMB_00482 4.4e-86 ykoJ S Peptidase propeptide and YPEB domain
BHKMAKMB_00485 2.2e-222 mgtE P Acts as a magnesium transporter
BHKMAKMB_00486 1.4e-53 tnrA K transcriptional
BHKMAKMB_00487 5.9e-18
BHKMAKMB_00488 6.9e-26 ykoL
BHKMAKMB_00489 1.3e-81 mhqR K transcriptional
BHKMAKMB_00490 2.3e-220 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
BHKMAKMB_00491 3.7e-99 ykoP G polysaccharide deacetylase
BHKMAKMB_00492 7.1e-155 ykoQ S Calcineurin-like phosphoesterase superfamily domain
BHKMAKMB_00493 0.0 ykoS
BHKMAKMB_00494 2.5e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
BHKMAKMB_00495 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
BHKMAKMB_00496 3.2e-161 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BHKMAKMB_00497 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
BHKMAKMB_00498 1.4e-116 ykoX S membrane-associated protein
BHKMAKMB_00499 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
BHKMAKMB_00500 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BHKMAKMB_00501 8.2e-117 rsgI S Anti-sigma factor N-terminus
BHKMAKMB_00502 1.9e-26 sspD S small acid-soluble spore protein
BHKMAKMB_00503 1.5e-124 ykrK S Domain of unknown function (DUF1836)
BHKMAKMB_00504 7e-156 htpX O Belongs to the peptidase M48B family
BHKMAKMB_00505 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
BHKMAKMB_00506 1.2e-10 ydfR S Protein of unknown function (DUF421)
BHKMAKMB_00507 4.5e-22 ykzE
BHKMAKMB_00508 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
BHKMAKMB_00509 0.0 kinE 2.7.13.3 T Histidine kinase
BHKMAKMB_00510 7e-89 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BHKMAKMB_00512 3.3e-197 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BHKMAKMB_00513 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BHKMAKMB_00514 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
BHKMAKMB_00515 8e-232 mtnE 2.6.1.83 E Aminotransferase
BHKMAKMB_00516 4.1e-231 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
BHKMAKMB_00517 7.5e-137 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BHKMAKMB_00518 7.2e-115 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
BHKMAKMB_00519 1.3e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BHKMAKMB_00520 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
BHKMAKMB_00521 6.4e-09 S Spo0E like sporulation regulatory protein
BHKMAKMB_00522 1.4e-64 eag
BHKMAKMB_00523 2.5e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
BHKMAKMB_00524 1.3e-75 ykvE K transcriptional
BHKMAKMB_00525 2.5e-125 motB N Flagellar motor protein
BHKMAKMB_00526 2.7e-138 motA N flagellar motor
BHKMAKMB_00527 0.0 clpE O Belongs to the ClpA ClpB family
BHKMAKMB_00528 8.7e-182 ykvI S membrane
BHKMAKMB_00529 7.3e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BHKMAKMB_00530 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
BHKMAKMB_00531 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
BHKMAKMB_00532 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BHKMAKMB_00533 2e-61 ykvN K Transcriptional regulator
BHKMAKMB_00534 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
BHKMAKMB_00535 4e-217 ykvP 3.5.1.28 M Glycosyl transferases group 1
BHKMAKMB_00536 1.2e-35 3.5.1.104 M LysM domain
BHKMAKMB_00537 8.5e-133 G Glycosyl hydrolases family 18
BHKMAKMB_00538 5.6e-46 ykvR S Protein of unknown function (DUF3219)
BHKMAKMB_00539 6e-25 ykvS S protein conserved in bacteria
BHKMAKMB_00540 2.8e-28
BHKMAKMB_00541 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
BHKMAKMB_00542 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
BHKMAKMB_00543 4.9e-90 stoA CO thiol-disulfide
BHKMAKMB_00544 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
BHKMAKMB_00545 3.8e-09
BHKMAKMB_00546 8.7e-209 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
BHKMAKMB_00548 9.8e-180 ykvZ 5.1.1.1 K Transcriptional regulator
BHKMAKMB_00550 4.5e-128 glcT K antiterminator
BHKMAKMB_00551 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
BHKMAKMB_00552 2.1e-39 ptsH G phosphocarrier protein HPr
BHKMAKMB_00553 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BHKMAKMB_00554 7.2e-39 splA S Transcriptional regulator
BHKMAKMB_00555 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
BHKMAKMB_00556 1.2e-131 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
BHKMAKMB_00557 2e-264 mcpC NT chemotaxis protein
BHKMAKMB_00558 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
BHKMAKMB_00559 8e-124 ykwD J protein with SCP PR1 domains
BHKMAKMB_00560 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
BHKMAKMB_00561 0.0 pilS 2.7.13.3 T Histidine kinase
BHKMAKMB_00562 8e-224 patA 2.6.1.1 E Aminotransferase
BHKMAKMB_00563 2.2e-15
BHKMAKMB_00564 1.6e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
BHKMAKMB_00565 1.7e-84 ykyB S YkyB-like protein
BHKMAKMB_00566 1.6e-238 ykuC EGP Major facilitator Superfamily
BHKMAKMB_00567 4.6e-88 ykuD S protein conserved in bacteria
BHKMAKMB_00568 9.4e-166 ykuE S Metallophosphoesterase
BHKMAKMB_00569 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
BHKMAKMB_00570 0.0 3.2.1.132 M Putative peptidoglycan binding domain
BHKMAKMB_00571 1.7e-93 M Peptidoglycan-binding domain 1 protein
BHKMAKMB_00573 5.2e-234 ykuI T Diguanylate phosphodiesterase
BHKMAKMB_00574 3.9e-37 ykuJ S protein conserved in bacteria
BHKMAKMB_00575 4.4e-94 ykuK S Ribonuclease H-like
BHKMAKMB_00576 3.9e-27 ykzF S Antirepressor AbbA
BHKMAKMB_00577 1.6e-76 ykuL S CBS domain
BHKMAKMB_00578 3.5e-168 ccpC K Transcriptional regulator
BHKMAKMB_00579 5.7e-88 fld C Flavodoxin domain
BHKMAKMB_00580 3.2e-177 ykuO
BHKMAKMB_00581 3.2e-80 fld C Flavodoxin
BHKMAKMB_00582 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
BHKMAKMB_00583 5.8e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
BHKMAKMB_00584 9e-37 ykuS S Belongs to the UPF0180 family
BHKMAKMB_00585 8.8e-142 ykuT M Mechanosensitive ion channel
BHKMAKMB_00586 3.9e-101 ykuU O Alkyl hydroperoxide reductase
BHKMAKMB_00587 4.4e-82 ykuV CO thiol-disulfide
BHKMAKMB_00588 5.8e-95 rok K Repressor of ComK
BHKMAKMB_00589 2.9e-147 yknT
BHKMAKMB_00590 3.9e-110 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
BHKMAKMB_00591 5.3e-192 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
BHKMAKMB_00592 8.1e-246 moeA 2.10.1.1 H molybdopterin
BHKMAKMB_00593 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
BHKMAKMB_00594 8.5e-84 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
BHKMAKMB_00595 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BHKMAKMB_00596 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
BHKMAKMB_00597 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
BHKMAKMB_00598 1e-117 yknW S Yip1 domain
BHKMAKMB_00599 3e-159 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BHKMAKMB_00600 2.5e-124 macB V ABC transporter, ATP-binding protein
BHKMAKMB_00601 2.1e-211 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
BHKMAKMB_00602 3.1e-136 fruR K Transcriptional regulator
BHKMAKMB_00603 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
BHKMAKMB_00604 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
BHKMAKMB_00605 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
BHKMAKMB_00606 8.1e-39 ykoA
BHKMAKMB_00607 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
BHKMAKMB_00608 1.5e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BHKMAKMB_00609 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
BHKMAKMB_00610 1.1e-12 S Uncharacterized protein YkpC
BHKMAKMB_00611 7.7e-183 mreB D Rod-share determining protein MreBH
BHKMAKMB_00612 1.5e-43 abrB K of stationary sporulation gene expression
BHKMAKMB_00613 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
BHKMAKMB_00614 1.6e-162 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
BHKMAKMB_00615 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
BHKMAKMB_00616 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BHKMAKMB_00617 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BHKMAKMB_00618 8.2e-31 ykzG S Belongs to the UPF0356 family
BHKMAKMB_00619 1.4e-147 ykrA S hydrolases of the HAD superfamily
BHKMAKMB_00620 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
BHKMAKMB_00622 2e-115 recN L Putative cell-wall binding lipoprotein
BHKMAKMB_00623 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
BHKMAKMB_00624 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
BHKMAKMB_00625 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
BHKMAKMB_00626 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
BHKMAKMB_00627 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
BHKMAKMB_00628 3.5e-277 speA 4.1.1.19 E Arginine
BHKMAKMB_00629 1.6e-42 yktA S Belongs to the UPF0223 family
BHKMAKMB_00630 7.1e-118 yktB S Belongs to the UPF0637 family
BHKMAKMB_00631 7.1e-26 ykzI
BHKMAKMB_00632 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
BHKMAKMB_00633 6.9e-78 ykzC S Acetyltransferase (GNAT) family
BHKMAKMB_00634 6.5e-173 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BHKMAKMB_00635 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
BHKMAKMB_00636 0.0 ylaA
BHKMAKMB_00637 2.7e-42 ylaB
BHKMAKMB_00638 2.7e-91 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
BHKMAKMB_00639 1.2e-11 sigC S Putative zinc-finger
BHKMAKMB_00640 1.8e-38 ylaE
BHKMAKMB_00641 8.2e-22 S Family of unknown function (DUF5325)
BHKMAKMB_00642 0.0 typA T GTP-binding protein TypA
BHKMAKMB_00643 4.2e-47 ylaH S YlaH-like protein
BHKMAKMB_00644 2.5e-32 ylaI S protein conserved in bacteria
BHKMAKMB_00645 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
BHKMAKMB_00646 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
BHKMAKMB_00647 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BHKMAKMB_00648 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
BHKMAKMB_00649 8.7e-44 ylaN S Belongs to the UPF0358 family
BHKMAKMB_00650 4.5e-214 ftsW D Belongs to the SEDS family
BHKMAKMB_00651 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BHKMAKMB_00652 2.6e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
BHKMAKMB_00653 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
BHKMAKMB_00654 6.2e-191 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
BHKMAKMB_00655 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BHKMAKMB_00656 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
BHKMAKMB_00657 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
BHKMAKMB_00658 3e-167 ctaG S cytochrome c oxidase
BHKMAKMB_00659 7e-62 ylbA S YugN-like family
BHKMAKMB_00660 2.6e-74 ylbB T COG0517 FOG CBS domain
BHKMAKMB_00661 3e-201 ylbC S protein with SCP PR1 domains
BHKMAKMB_00662 4.1e-63 ylbD S Putative coat protein
BHKMAKMB_00663 6.7e-37 ylbE S YlbE-like protein
BHKMAKMB_00664 1.8e-75 ylbF S Belongs to the UPF0342 family
BHKMAKMB_00665 7.5e-39 ylbG S UPF0298 protein
BHKMAKMB_00666 1.9e-98 rsmD 2.1.1.171 L Methyltransferase
BHKMAKMB_00667 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BHKMAKMB_00668 3.8e-221 ylbJ S Sporulation integral membrane protein YlbJ
BHKMAKMB_00669 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
BHKMAKMB_00670 6.8e-187 ylbL T Belongs to the peptidase S16 family
BHKMAKMB_00671 2.8e-235 ylbM S Belongs to the UPF0348 family
BHKMAKMB_00673 1.3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
BHKMAKMB_00674 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
BHKMAKMB_00675 6.8e-75 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
BHKMAKMB_00676 4e-89 ylbP K n-acetyltransferase
BHKMAKMB_00677 7.3e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BHKMAKMB_00678 2.9e-309 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BHKMAKMB_00679 2.9e-78 mraZ K Belongs to the MraZ family
BHKMAKMB_00680 6.6e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
BHKMAKMB_00681 3.7e-44 ftsL D Essential cell division protein
BHKMAKMB_00682 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
BHKMAKMB_00683 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
BHKMAKMB_00684 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BHKMAKMB_00685 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BHKMAKMB_00686 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BHKMAKMB_00687 5.7e-186 spoVE D Belongs to the SEDS family
BHKMAKMB_00688 2.3e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BHKMAKMB_00689 5.3e-167 murB 1.3.1.98 M cell wall formation
BHKMAKMB_00690 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
BHKMAKMB_00691 2.4e-103 ylxW S protein conserved in bacteria
BHKMAKMB_00692 1e-102 ylxX S protein conserved in bacteria
BHKMAKMB_00693 6.2e-58 sbp S small basic protein
BHKMAKMB_00694 2.4e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
BHKMAKMB_00695 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BHKMAKMB_00696 0.0 bpr O COG1404 Subtilisin-like serine proteases
BHKMAKMB_00697 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
BHKMAKMB_00698 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BHKMAKMB_00699 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BHKMAKMB_00700 1.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
BHKMAKMB_00701 1.3e-256 argE 3.5.1.16 E Acetylornithine deacetylase
BHKMAKMB_00702 2.4e-37 ylmC S sporulation protein
BHKMAKMB_00703 1.1e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
BHKMAKMB_00704 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BHKMAKMB_00705 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
BHKMAKMB_00706 1.3e-39 yggT S membrane
BHKMAKMB_00707 6.7e-139 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
BHKMAKMB_00708 2.6e-67 divIVA D Cell division initiation protein
BHKMAKMB_00709 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BHKMAKMB_00710 1.3e-63 dksA T COG1734 DnaK suppressor protein
BHKMAKMB_00711 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BHKMAKMB_00712 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
BHKMAKMB_00713 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BHKMAKMB_00714 9e-232 pyrP F Xanthine uracil
BHKMAKMB_00715 1.4e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
BHKMAKMB_00716 1.7e-251 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
BHKMAKMB_00717 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
BHKMAKMB_00718 0.0 carB 6.3.5.5 F Belongs to the CarB family
BHKMAKMB_00719 4.8e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
BHKMAKMB_00720 2.9e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
BHKMAKMB_00721 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
BHKMAKMB_00722 2.9e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BHKMAKMB_00724 3.5e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
BHKMAKMB_00725 1.1e-179 cysP P phosphate transporter
BHKMAKMB_00726 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
BHKMAKMB_00727 7.3e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
BHKMAKMB_00728 2.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
BHKMAKMB_00729 2e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
BHKMAKMB_00730 4.3e-83 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
BHKMAKMB_00731 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
BHKMAKMB_00732 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
BHKMAKMB_00733 2.4e-156 yloC S stress-induced protein
BHKMAKMB_00734 1.5e-40 ylzA S Belongs to the UPF0296 family
BHKMAKMB_00735 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
BHKMAKMB_00736 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
BHKMAKMB_00737 8.8e-226 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BHKMAKMB_00738 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BHKMAKMB_00739 6e-85 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
BHKMAKMB_00740 3.8e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BHKMAKMB_00741 2.9e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BHKMAKMB_00742 4.8e-207 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
BHKMAKMB_00743 2.4e-141 stp 3.1.3.16 T phosphatase
BHKMAKMB_00744 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
BHKMAKMB_00745 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
BHKMAKMB_00746 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
BHKMAKMB_00747 3.1e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
BHKMAKMB_00748 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
BHKMAKMB_00749 5.5e-59 asp S protein conserved in bacteria
BHKMAKMB_00750 2.7e-302 yloV S kinase related to dihydroxyacetone kinase
BHKMAKMB_00751 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
BHKMAKMB_00752 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
BHKMAKMB_00753 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BHKMAKMB_00754 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
BHKMAKMB_00755 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
BHKMAKMB_00756 9.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
BHKMAKMB_00757 6.1e-129 IQ reductase
BHKMAKMB_00758 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
BHKMAKMB_00759 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
BHKMAKMB_00760 0.0 smc D Required for chromosome condensation and partitioning
BHKMAKMB_00761 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
BHKMAKMB_00762 2.9e-87
BHKMAKMB_00763 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BHKMAKMB_00764 6e-236 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BHKMAKMB_00765 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
BHKMAKMB_00766 1.2e-36 ylqC S Belongs to the UPF0109 family
BHKMAKMB_00767 1.3e-61 ylqD S YlqD protein
BHKMAKMB_00768 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BHKMAKMB_00769 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
BHKMAKMB_00770 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
BHKMAKMB_00771 4.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BHKMAKMB_00772 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BHKMAKMB_00773 8.5e-291 ylqG
BHKMAKMB_00774 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
BHKMAKMB_00775 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
BHKMAKMB_00776 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BHKMAKMB_00777 1.7e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
BHKMAKMB_00778 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BHKMAKMB_00779 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BHKMAKMB_00780 2.5e-169 xerC L tyrosine recombinase XerC
BHKMAKMB_00781 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BHKMAKMB_00782 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BHKMAKMB_00783 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BHKMAKMB_00784 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
BHKMAKMB_00785 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
BHKMAKMB_00786 1.9e-31 fliE N Flagellar hook-basal body
BHKMAKMB_00787 2.4e-255 fliF N The M ring may be actively involved in energy transduction
BHKMAKMB_00788 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
BHKMAKMB_00789 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
BHKMAKMB_00790 2.5e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
BHKMAKMB_00791 1.5e-69 fliJ N Flagellar biosynthesis chaperone
BHKMAKMB_00792 7.7e-37 ylxF S MgtE intracellular N domain
BHKMAKMB_00793 1.2e-221 fliK N Flagellar hook-length control protein
BHKMAKMB_00794 1.7e-72 flgD N Flagellar basal body rod modification protein
BHKMAKMB_00795 8.2e-140 flgG N Flagellar basal body rod
BHKMAKMB_00796 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
BHKMAKMB_00797 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
BHKMAKMB_00798 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BHKMAKMB_00799 1.6e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
BHKMAKMB_00800 9.3e-97 fliZ N Flagellar biosynthesis protein, FliO
BHKMAKMB_00801 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
BHKMAKMB_00802 2.2e-36 fliQ N Role in flagellar biosynthesis
BHKMAKMB_00803 3.6e-132 fliR N Flagellar biosynthetic protein FliR
BHKMAKMB_00804 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BHKMAKMB_00805 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BHKMAKMB_00806 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
BHKMAKMB_00807 7.5e-158 flhG D Belongs to the ParA family
BHKMAKMB_00808 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
BHKMAKMB_00809 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
BHKMAKMB_00810 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
BHKMAKMB_00811 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
BHKMAKMB_00812 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
BHKMAKMB_00813 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BHKMAKMB_00814 4.3e-78 ylxL
BHKMAKMB_00815 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
BHKMAKMB_00816 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BHKMAKMB_00817 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
BHKMAKMB_00818 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
BHKMAKMB_00819 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BHKMAKMB_00820 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
BHKMAKMB_00821 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
BHKMAKMB_00822 7.7e-233 rasP M zinc metalloprotease
BHKMAKMB_00823 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
BHKMAKMB_00824 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BHKMAKMB_00825 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
BHKMAKMB_00826 1.1e-203 nusA K Participates in both transcription termination and antitermination
BHKMAKMB_00827 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
BHKMAKMB_00828 3.1e-47 ylxQ J ribosomal protein
BHKMAKMB_00829 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BHKMAKMB_00830 3e-44 ylxP S protein conserved in bacteria
BHKMAKMB_00831 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BHKMAKMB_00832 1.3e-173 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BHKMAKMB_00833 6.1e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
BHKMAKMB_00834 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BHKMAKMB_00835 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
BHKMAKMB_00836 4.2e-183 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
BHKMAKMB_00837 4.4e-233 pepR S Belongs to the peptidase M16 family
BHKMAKMB_00838 2.6e-42 ymxH S YlmC YmxH family
BHKMAKMB_00839 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
BHKMAKMB_00840 4.3e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
BHKMAKMB_00841 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BHKMAKMB_00842 5.9e-222 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
BHKMAKMB_00843 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BHKMAKMB_00844 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BHKMAKMB_00845 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
BHKMAKMB_00846 4.4e-32 S YlzJ-like protein
BHKMAKMB_00847 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
BHKMAKMB_00848 1.4e-133 ymfC K Transcriptional regulator
BHKMAKMB_00849 1.5e-206 ymfD EGP Major facilitator Superfamily
BHKMAKMB_00850 2.6e-236 ymfF S Peptidase M16
BHKMAKMB_00851 1.4e-242 ymfH S zinc protease
BHKMAKMB_00852 9.2e-130 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
BHKMAKMB_00853 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
BHKMAKMB_00854 2.4e-76 ymfK S Protein of unknown function (DUF3388)
BHKMAKMB_00855 3.1e-53 ymfK S Protein of unknown function (DUF3388)
BHKMAKMB_00856 1.9e-124 ymfM S protein conserved in bacteria
BHKMAKMB_00857 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BHKMAKMB_00858 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
BHKMAKMB_00859 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BHKMAKMB_00860 1e-215 pbpX V Beta-lactamase
BHKMAKMB_00861 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
BHKMAKMB_00862 1.9e-152 ymdB S protein conserved in bacteria
BHKMAKMB_00863 1.2e-36 spoVS S Stage V sporulation protein S
BHKMAKMB_00864 2.7e-199 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
BHKMAKMB_00865 6.5e-218 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
BHKMAKMB_00866 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BHKMAKMB_00867 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
BHKMAKMB_00868 2.2e-88 cotE S Spore coat protein
BHKMAKMB_00869 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BHKMAKMB_00870 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BHKMAKMB_00871 2.3e-70 S Regulatory protein YrvL
BHKMAKMB_00873 1.2e-97 ymcC S Membrane
BHKMAKMB_00874 4.4e-109 pksA K Transcriptional regulator
BHKMAKMB_00875 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
BHKMAKMB_00876 2.6e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
BHKMAKMB_00877 2.4e-186 pksD Q Acyl transferase domain
BHKMAKMB_00878 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
BHKMAKMB_00879 1.4e-37 acpK IQ Phosphopantetheine attachment site
BHKMAKMB_00880 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
BHKMAKMB_00881 1.3e-245 pksG 2.3.3.10 I synthase
BHKMAKMB_00882 2.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
BHKMAKMB_00883 2.7e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
BHKMAKMB_00884 0.0 rhiB IQ polyketide synthase
BHKMAKMB_00885 0.0 pfaA Q Polyketide synthase of type I
BHKMAKMB_00886 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
BHKMAKMB_00887 0.0 dhbF IQ polyketide synthase
BHKMAKMB_00888 0.0 dhbF IQ polyketide synthase
BHKMAKMB_00889 0.0 pks13 HQ Beta-ketoacyl synthase
BHKMAKMB_00890 2.5e-233 cypA C Cytochrome P450
BHKMAKMB_00891 1.2e-61 ymzB
BHKMAKMB_00892 6.6e-164 ymaE S Metallo-beta-lactamase superfamily
BHKMAKMB_00893 4.6e-252 aprX O Belongs to the peptidase S8 family
BHKMAKMB_00894 2.1e-126 ymaC S Replication protein
BHKMAKMB_00895 5.4e-80 ymaD O redox protein, regulator of disulfide bond formation
BHKMAKMB_00896 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
BHKMAKMB_00897 4.9e-51 ebrA P Small Multidrug Resistance protein
BHKMAKMB_00899 2.1e-46 ymaF S YmaF family
BHKMAKMB_00900 9.3e-175 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BHKMAKMB_00901 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
BHKMAKMB_00902 6.3e-23
BHKMAKMB_00903 4.5e-22 ymzA
BHKMAKMB_00904 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
BHKMAKMB_00905 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BHKMAKMB_00906 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BHKMAKMB_00907 2e-109 ymaB
BHKMAKMB_00908 8e-116 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
BHKMAKMB_00909 1.7e-176 spoVK O stage V sporulation protein K
BHKMAKMB_00910 5.5e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BHKMAKMB_00911 3.3e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
BHKMAKMB_00912 1.1e-68 glnR K transcriptional
BHKMAKMB_00913 7e-261 glnA 6.3.1.2 E glutamine synthetase
BHKMAKMB_00914 5e-10
BHKMAKMB_00915 2.5e-32
BHKMAKMB_00916 5.8e-39
BHKMAKMB_00917 6.8e-80 G regulation of fungal-type cell wall biogenesis
BHKMAKMB_00918 4.9e-145 ynaC
BHKMAKMB_00919 2e-99 ynaD J Acetyltransferase (GNAT) domain
BHKMAKMB_00920 1.9e-123 ynaE S Domain of unknown function (DUF3885)
BHKMAKMB_00921 6.4e-60 ynaF
BHKMAKMB_00924 1.1e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
BHKMAKMB_00925 2.7e-255 xynT G MFS/sugar transport protein
BHKMAKMB_00926 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
BHKMAKMB_00927 1e-215 xylR GK ROK family
BHKMAKMB_00928 4e-264 xylA 5.3.1.5 G Belongs to the xylose isomerase family
BHKMAKMB_00929 6e-293 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
BHKMAKMB_00930 1.4e-113 yokF 3.1.31.1 L RNA catabolic process
BHKMAKMB_00931 3.5e-247 iolT EGP Major facilitator Superfamily
BHKMAKMB_00932 2.7e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BHKMAKMB_00933 6.3e-84 yncE S Protein of unknown function (DUF2691)
BHKMAKMB_00934 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
BHKMAKMB_00935 5.2e-15
BHKMAKMB_00938 1.2e-165 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BHKMAKMB_00940 1.3e-134 S Domain of unknown function, YrpD
BHKMAKMB_00943 7.9e-25 tatA U protein secretion
BHKMAKMB_00944 1.8e-71
BHKMAKMB_00945 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
BHKMAKMB_00948 5.7e-286 gerAA EG Spore germination protein
BHKMAKMB_00949 4.5e-197 gerAB U Spore germination
BHKMAKMB_00950 4.2e-220 gerLC S Spore germination protein
BHKMAKMB_00951 7.7e-154 yndG S DoxX-like family
BHKMAKMB_00952 2.6e-117 yndH S Domain of unknown function (DUF4166)
BHKMAKMB_00953 0.0 yndJ S YndJ-like protein
BHKMAKMB_00955 8.6e-139 yndL S Replication protein
BHKMAKMB_00956 5.8e-74 yndM S Protein of unknown function (DUF2512)
BHKMAKMB_00957 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
BHKMAKMB_00959 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BHKMAKMB_00960 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
BHKMAKMB_00961 9.2e-113 yneB L resolvase
BHKMAKMB_00962 1.3e-32 ynzC S UPF0291 protein
BHKMAKMB_00963 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BHKMAKMB_00964 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
BHKMAKMB_00965 1.8e-28 yneF S UPF0154 protein
BHKMAKMB_00966 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
BHKMAKMB_00967 7.1e-127 ccdA O cytochrome c biogenesis protein
BHKMAKMB_00968 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
BHKMAKMB_00969 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
BHKMAKMB_00970 4.2e-74 yneK S Protein of unknown function (DUF2621)
BHKMAKMB_00971 4.1e-65 hspX O Spore coat protein
BHKMAKMB_00972 3.9e-19 sspP S Belongs to the SspP family
BHKMAKMB_00973 2.2e-14 sspO S Belongs to the SspO family
BHKMAKMB_00974 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BHKMAKMB_00975 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BHKMAKMB_00977 3.1e-08 sspN S Small acid-soluble spore protein N family
BHKMAKMB_00978 3.9e-35 tlp S Belongs to the Tlp family
BHKMAKMB_00979 1.2e-73 yneP S Thioesterase-like superfamily
BHKMAKMB_00980 1.3e-53 yneQ
BHKMAKMB_00981 4.1e-49 yneR S Belongs to the HesB IscA family
BHKMAKMB_00982 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
BHKMAKMB_00983 6.6e-69 yccU S CoA-binding protein
BHKMAKMB_00984 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
BHKMAKMB_00985 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
BHKMAKMB_00986 5.9e-43 ynfC
BHKMAKMB_00987 8.2e-252 agcS E Sodium alanine symporter
BHKMAKMB_00988 2.4e-297 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
BHKMAKMB_00990 3.7e-251 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
BHKMAKMB_00991 4.4e-299 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
BHKMAKMB_00992 2.4e-80 yngA S membrane
BHKMAKMB_00993 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
BHKMAKMB_00994 5.5e-104 yngC S membrane-associated protein
BHKMAKMB_00995 1.9e-233 nrnB S phosphohydrolase (DHH superfamily)
BHKMAKMB_00996 6.3e-290 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
BHKMAKMB_00997 2.2e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
BHKMAKMB_00998 8e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
BHKMAKMB_00999 6e-32 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
BHKMAKMB_01000 3e-251 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
BHKMAKMB_01001 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
BHKMAKMB_01002 4.4e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
BHKMAKMB_01003 1.8e-31 S Family of unknown function (DUF5367)
BHKMAKMB_01004 1.3e-306 yngK T Glycosyl hydrolase-like 10
BHKMAKMB_01005 2.8e-64 yngL S Protein of unknown function (DUF1360)
BHKMAKMB_01006 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
BHKMAKMB_01007 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
BHKMAKMB_01008 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
BHKMAKMB_01009 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
BHKMAKMB_01010 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
BHKMAKMB_01011 4.3e-275 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
BHKMAKMB_01012 6e-193 yoxA 5.1.3.3 G Aldose 1-epimerase
BHKMAKMB_01013 2.3e-246 yoeA V MATE efflux family protein
BHKMAKMB_01014 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
BHKMAKMB_01016 2.2e-96 L Integrase
BHKMAKMB_01017 3e-34 yoeD G Helix-turn-helix domain
BHKMAKMB_01018 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
BHKMAKMB_01019 2.5e-158 gltR1 K Transcriptional regulator
BHKMAKMB_01020 5e-187 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
BHKMAKMB_01021 2.7e-293 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
BHKMAKMB_01022 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
BHKMAKMB_01023 7.8e-155 gltC K Transcriptional regulator
BHKMAKMB_01024 4.1e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BHKMAKMB_01025 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BHKMAKMB_01026 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
BHKMAKMB_01027 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
BHKMAKMB_01028 3e-42 yoxC S Bacterial protein of unknown function (DUF948)
BHKMAKMB_01029 3.1e-144 yoxB
BHKMAKMB_01030 7.5e-97 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
BHKMAKMB_01031 6.2e-235 yoaB EGP Major facilitator Superfamily
BHKMAKMB_01032 1e-284 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
BHKMAKMB_01033 1.7e-190 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BHKMAKMB_01034 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BHKMAKMB_01035 1.9e-33 yoaF
BHKMAKMB_01036 2.2e-08 ywlA S Uncharacterised protein family (UPF0715)
BHKMAKMB_01037 7e-14
BHKMAKMB_01038 1.5e-38 S Protein of unknown function (DUF4025)
BHKMAKMB_01039 1.7e-187 mcpU NT methyl-accepting chemotaxis protein
BHKMAKMB_01040 8.7e-281 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
BHKMAKMB_01041 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
BHKMAKMB_01042 2.3e-111 yoaK S Membrane
BHKMAKMB_01043 2.3e-198 pelB 4.2.2.10, 4.2.2.2 G Amb_all
BHKMAKMB_01044 1.1e-132 yoqW S Belongs to the SOS response-associated peptidase family
BHKMAKMB_01046 3.8e-234 oxdC 4.1.1.2 G Oxalate decarboxylase
BHKMAKMB_01048 1.5e-146 yoaP 3.1.3.18 K YoaP-like
BHKMAKMB_01049 1.2e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
BHKMAKMB_01050 4.1e-89
BHKMAKMB_01051 2.4e-172 yoaR V vancomycin resistance protein
BHKMAKMB_01052 4.3e-75 yoaS S Protein of unknown function (DUF2975)
BHKMAKMB_01053 4.2e-37 yozG K Transcriptional regulator
BHKMAKMB_01054 1.1e-149 yoaT S Protein of unknown function (DUF817)
BHKMAKMB_01055 8.6e-159 yoaU K LysR substrate binding domain
BHKMAKMB_01056 6e-160 yijE EG EamA-like transporter family
BHKMAKMB_01057 3.7e-78 yoaW
BHKMAKMB_01058 1.1e-118 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
BHKMAKMB_01059 2.3e-170 bla 3.5.2.6 V beta-lactamase
BHKMAKMB_01063 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
BHKMAKMB_01064 1.8e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
BHKMAKMB_01065 1.4e-37 S TM2 domain
BHKMAKMB_01066 5.7e-58 K Helix-turn-helix
BHKMAKMB_01068 1.6e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
BHKMAKMB_01069 6.6e-127 yoqW S Belongs to the SOS response-associated peptidase family
BHKMAKMB_01070 1.8e-178 yobF
BHKMAKMB_01075 1.7e-207 S aspartate phosphatase
BHKMAKMB_01077 1.2e-123 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BHKMAKMB_01078 1.4e-59 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BHKMAKMB_01079 2.6e-38 S YolD-like protein
BHKMAKMB_01080 1.2e-49
BHKMAKMB_01081 0.0 K Psort location Cytoplasmic, score
BHKMAKMB_01082 2.7e-157 yobJ
BHKMAKMB_01083 3e-86 S SMI1-KNR4 cell-wall
BHKMAKMB_01084 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
BHKMAKMB_01085 7.9e-105 yokH G SMI1 / KNR4 family
BHKMAKMB_01086 9.5e-280 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
BHKMAKMB_01087 0.0 yobO M Pectate lyase superfamily protein
BHKMAKMB_01088 9.9e-55 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
BHKMAKMB_01089 1e-136 yobQ K helix_turn_helix, arabinose operon control protein
BHKMAKMB_01090 2.5e-143 yobR 2.3.1.1 J FR47-like protein
BHKMAKMB_01091 3e-99 yobS K Transcriptional regulator
BHKMAKMB_01092 4.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
BHKMAKMB_01093 1.5e-88 yobU K Bacterial transcription activator, effector binding domain
BHKMAKMB_01094 9e-178 yobV K WYL domain
BHKMAKMB_01095 2.5e-95 yobW
BHKMAKMB_01096 1e-51 czrA K transcriptional
BHKMAKMB_01097 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
BHKMAKMB_01098 1.5e-92 yozB S membrane
BHKMAKMB_01099 2.2e-145
BHKMAKMB_01100 1.9e-94 yocC
BHKMAKMB_01101 6.9e-189 yocD 3.4.17.13 V peptidase S66
BHKMAKMB_01102 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
BHKMAKMB_01103 3.2e-198 desK 2.7.13.3 T Histidine kinase
BHKMAKMB_01104 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
BHKMAKMB_01105 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
BHKMAKMB_01106 0.0 recQ 3.6.4.12 L DNA helicase
BHKMAKMB_01107 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BHKMAKMB_01108 3.3e-83 dksA T general stress protein
BHKMAKMB_01109 6.4e-54 yocL
BHKMAKMB_01110 6.6e-34
BHKMAKMB_01111 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
BHKMAKMB_01112 1.1e-40 yozN
BHKMAKMB_01113 1.9e-36 yocN
BHKMAKMB_01114 4.2e-56 yozO S Bacterial PH domain
BHKMAKMB_01115 2.7e-31 yozC
BHKMAKMB_01116 4e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
BHKMAKMB_01117 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
BHKMAKMB_01118 5.4e-166 sodA 1.15.1.1 P Superoxide dismutase
BHKMAKMB_01119 3.4e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
BHKMAKMB_01120 5.1e-168 yocS S -transporter
BHKMAKMB_01121 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
BHKMAKMB_01122 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
BHKMAKMB_01123 0.0 yojO P Von Willebrand factor
BHKMAKMB_01124 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
BHKMAKMB_01125 1e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BHKMAKMB_01126 1.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
BHKMAKMB_01127 1.8e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
BHKMAKMB_01128 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BHKMAKMB_01130 4.2e-245 norM V Multidrug efflux pump
BHKMAKMB_01131 8.4e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
BHKMAKMB_01132 2.1e-125 yojG S deacetylase
BHKMAKMB_01133 2.2e-60 yojF S Protein of unknown function (DUF1806)
BHKMAKMB_01134 1.5e-43
BHKMAKMB_01135 3.5e-163 rarD S -transporter
BHKMAKMB_01136 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
BHKMAKMB_01137 3.4e-09
BHKMAKMB_01138 8.2e-209 gntP EG COG2610 H gluconate symporter and related permeases
BHKMAKMB_01139 3.8e-66 yodA S tautomerase
BHKMAKMB_01140 1.7e-57 yodB K transcriptional
BHKMAKMB_01141 4.8e-108 yodC C nitroreductase
BHKMAKMB_01142 3.8e-113 mhqD S Carboxylesterase
BHKMAKMB_01143 5.8e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
BHKMAKMB_01144 6.2e-28 S Protein of unknown function (DUF3311)
BHKMAKMB_01145 4.2e-270 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BHKMAKMB_01146 1.9e-253 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
BHKMAKMB_01147 1.7e-128 yodH Q Methyltransferase
BHKMAKMB_01148 5.2e-24 yodI
BHKMAKMB_01149 2.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
BHKMAKMB_01150 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
BHKMAKMB_01151 5.3e-09
BHKMAKMB_01152 3.6e-54 yodL S YodL-like
BHKMAKMB_01153 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
BHKMAKMB_01154 2.8e-24 yozD S YozD-like protein
BHKMAKMB_01156 1.4e-124 yodN
BHKMAKMB_01157 1.4e-36 yozE S Belongs to the UPF0346 family
BHKMAKMB_01158 2.9e-47 yokU S YokU-like protein, putative antitoxin
BHKMAKMB_01159 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
BHKMAKMB_01160 2.5e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
BHKMAKMB_01161 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
BHKMAKMB_01162 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
BHKMAKMB_01163 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BHKMAKMB_01164 1.6e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BHKMAKMB_01167 2.9e-145 yiiD K acetyltransferase
BHKMAKMB_01168 1e-256 cgeD M maturation of the outermost layer of the spore
BHKMAKMB_01169 3.5e-38 cgeC
BHKMAKMB_01170 1.2e-65 cgeA
BHKMAKMB_01171 3.3e-188 cgeB S Spore maturation protein
BHKMAKMB_01172 3.6e-213 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
BHKMAKMB_01173 5.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
BHKMAKMB_01174 1.4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
BHKMAKMB_01175 7e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BHKMAKMB_01176 1.6e-70 ypoP K transcriptional
BHKMAKMB_01177 2.6e-223 mepA V MATE efflux family protein
BHKMAKMB_01178 5.5e-29 ypmT S Uncharacterized ympT
BHKMAKMB_01179 5e-99 ypmS S protein conserved in bacteria
BHKMAKMB_01180 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
BHKMAKMB_01181 3.2e-109 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
BHKMAKMB_01182 3.1e-40 ypmP S Protein of unknown function (DUF2535)
BHKMAKMB_01183 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BHKMAKMB_01184 1.6e-185 pspF K Transcriptional regulator
BHKMAKMB_01185 4.2e-110 hlyIII S protein, Hemolysin III
BHKMAKMB_01186 7.4e-112 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
BHKMAKMB_01187 7.9e-96 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BHKMAKMB_01188 4.3e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BHKMAKMB_01189 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
BHKMAKMB_01190 7.8e-114 ypjP S YpjP-like protein
BHKMAKMB_01191 1.3e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
BHKMAKMB_01192 1.7e-75 yphP S Belongs to the UPF0403 family
BHKMAKMB_01193 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
BHKMAKMB_01194 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
BHKMAKMB_01195 3.1e-110 ypgQ S phosphohydrolase
BHKMAKMB_01196 2.3e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
BHKMAKMB_01197 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BHKMAKMB_01198 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
BHKMAKMB_01199 7.9e-31 cspD K Cold-shock protein
BHKMAKMB_01200 3.8e-16 degR
BHKMAKMB_01201 8.1e-31 S Protein of unknown function (DUF2564)
BHKMAKMB_01202 2.6e-27 ypeQ S Zinc-finger
BHKMAKMB_01203 8.9e-127 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
BHKMAKMB_01204 5.4e-107 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BHKMAKMB_01205 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
BHKMAKMB_01207 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
BHKMAKMB_01208 2e-07
BHKMAKMB_01209 1e-38 ypbS S Protein of unknown function (DUF2533)
BHKMAKMB_01210 0.0 ypbR S Dynamin family
BHKMAKMB_01211 5.1e-87 ypbQ S protein conserved in bacteria
BHKMAKMB_01212 4.4e-208 bcsA Q Naringenin-chalcone synthase
BHKMAKMB_01213 1.6e-228 pbuX F xanthine
BHKMAKMB_01214 5.7e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
BHKMAKMB_01215 4.2e-294 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BHKMAKMB_01216 5e-171 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
BHKMAKMB_01217 7e-104 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
BHKMAKMB_01218 2.9e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
BHKMAKMB_01219 3.9e-187 ptxS K transcriptional
BHKMAKMB_01220 1.7e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BHKMAKMB_01221 7.1e-133 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
BHKMAKMB_01222 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
BHKMAKMB_01224 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
BHKMAKMB_01225 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
BHKMAKMB_01226 3.3e-92 ypsA S Belongs to the UPF0398 family
BHKMAKMB_01227 1.3e-237 yprB L RNase_H superfamily
BHKMAKMB_01228 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
BHKMAKMB_01229 1.9e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
BHKMAKMB_01230 8.6e-72 hspX O Belongs to the small heat shock protein (HSP20) family
BHKMAKMB_01231 1.2e-48 yppG S YppG-like protein
BHKMAKMB_01233 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
BHKMAKMB_01236 2.6e-188 yppC S Protein of unknown function (DUF2515)
BHKMAKMB_01237 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
BHKMAKMB_01238 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
BHKMAKMB_01239 4.7e-93 ypoC
BHKMAKMB_01240 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BHKMAKMB_01241 5.7e-129 dnaD L DNA replication protein DnaD
BHKMAKMB_01242 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
BHKMAKMB_01243 1.5e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
BHKMAKMB_01244 3.4e-80 ypmB S protein conserved in bacteria
BHKMAKMB_01245 6.7e-23 ypmA S Protein of unknown function (DUF4264)
BHKMAKMB_01246 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
BHKMAKMB_01247 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BHKMAKMB_01248 1.2e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BHKMAKMB_01249 6.6e-148 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
BHKMAKMB_01250 3.2e-178 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
BHKMAKMB_01251 1.3e-202 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
BHKMAKMB_01252 2.6e-203 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
BHKMAKMB_01253 1e-125 bshB1 S proteins, LmbE homologs
BHKMAKMB_01254 4.7e-70 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
BHKMAKMB_01255 6.1e-143 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
BHKMAKMB_01256 2.6e-55 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
BHKMAKMB_01257 2.4e-156 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
BHKMAKMB_01258 7.7e-138 ypjB S sporulation protein
BHKMAKMB_01259 5.6e-95 ypjA S membrane
BHKMAKMB_01260 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
BHKMAKMB_01261 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
BHKMAKMB_01262 1e-95 qcrA C Menaquinol-cytochrome c reductase
BHKMAKMB_01263 6.7e-75 ypiF S Protein of unknown function (DUF2487)
BHKMAKMB_01264 2.8e-99 ypiB S Belongs to the UPF0302 family
BHKMAKMB_01265 7.5e-228 S COG0457 FOG TPR repeat
BHKMAKMB_01266 1.6e-225 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
BHKMAKMB_01267 2.9e-199 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
BHKMAKMB_01268 2.1e-199 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BHKMAKMB_01269 1.6e-135 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
BHKMAKMB_01270 5.3e-223 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
BHKMAKMB_01271 6.3e-106 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
BHKMAKMB_01272 7.1e-117 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
BHKMAKMB_01273 9.7e-170 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BHKMAKMB_01274 7.3e-278 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BHKMAKMB_01275 3.7e-61 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
BHKMAKMB_01276 7.4e-200 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BHKMAKMB_01277 7.2e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BHKMAKMB_01278 5.7e-138 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
BHKMAKMB_01279 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
BHKMAKMB_01280 2.9e-193 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
BHKMAKMB_01281 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
BHKMAKMB_01282 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
BHKMAKMB_01283 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
BHKMAKMB_01284 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
BHKMAKMB_01285 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
BHKMAKMB_01286 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BHKMAKMB_01287 5.4e-138 yphF
BHKMAKMB_01288 1.6e-18 yphE S Protein of unknown function (DUF2768)
BHKMAKMB_01289 2.3e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
BHKMAKMB_01290 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
BHKMAKMB_01291 1.6e-28 ypzH
BHKMAKMB_01292 2.5e-161 seaA S YIEGIA protein
BHKMAKMB_01293 1.3e-102 yphA
BHKMAKMB_01294 1e-07 S YpzI-like protein
BHKMAKMB_01295 4.1e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
BHKMAKMB_01296 4.3e-206 rpsA 1.17.7.4 J Ribosomal protein S1
BHKMAKMB_01297 1.9e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
BHKMAKMB_01298 1.8e-23 S Family of unknown function (DUF5359)
BHKMAKMB_01299 9.2e-113 ypfA M Flagellar protein YcgR
BHKMAKMB_01300 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
BHKMAKMB_01301 4.7e-155 sleB 3.5.1.28 M Spore cortex-lytic enzyme
BHKMAKMB_01302 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
BHKMAKMB_01303 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
BHKMAKMB_01304 7.3e-247 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
BHKMAKMB_01305 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
BHKMAKMB_01306 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
BHKMAKMB_01307 2.8e-81 ypbF S Protein of unknown function (DUF2663)
BHKMAKMB_01308 4.6e-81 ypbE M Lysin motif
BHKMAKMB_01309 2.2e-100 ypbD S metal-dependent membrane protease
BHKMAKMB_01310 3.2e-286 recQ 3.6.4.12 L DNA helicase
BHKMAKMB_01311 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
BHKMAKMB_01312 4.7e-41 fer C Ferredoxin
BHKMAKMB_01313 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BHKMAKMB_01314 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BHKMAKMB_01315 9e-136 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
BHKMAKMB_01316 6.8e-201 rsiX
BHKMAKMB_01317 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
BHKMAKMB_01318 0.0 resE 2.7.13.3 T Histidine kinase
BHKMAKMB_01319 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BHKMAKMB_01320 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
BHKMAKMB_01321 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
BHKMAKMB_01322 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
BHKMAKMB_01323 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
BHKMAKMB_01324 1.9e-87 spmB S Spore maturation protein
BHKMAKMB_01325 3.5e-103 spmA S Spore maturation protein
BHKMAKMB_01326 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
BHKMAKMB_01327 4e-98 ypuI S Protein of unknown function (DUF3907)
BHKMAKMB_01328 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BHKMAKMB_01329 4.5e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BHKMAKMB_01330 4.5e-94 ypuF S Domain of unknown function (DUF309)
BHKMAKMB_01331 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
BHKMAKMB_01332 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
BHKMAKMB_01333 9.8e-230 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BHKMAKMB_01334 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
BHKMAKMB_01335 1.3e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BHKMAKMB_01336 6e-55 ypuD
BHKMAKMB_01337 5.2e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
BHKMAKMB_01338 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
BHKMAKMB_01339 1.5e-17 S SNARE associated Golgi protein
BHKMAKMB_01342 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BHKMAKMB_01343 1.3e-149 ypuA S Secreted protein
BHKMAKMB_01344 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
BHKMAKMB_01345 1.4e-273 spoVAF EG Stage V sporulation protein AF
BHKMAKMB_01346 1.4e-110 spoVAEA S stage V sporulation protein
BHKMAKMB_01347 2.2e-57 spoVAEB S stage V sporulation protein
BHKMAKMB_01348 9e-192 spoVAD I Stage V sporulation protein AD
BHKMAKMB_01349 2.3e-78 spoVAC S stage V sporulation protein AC
BHKMAKMB_01350 1e-67 spoVAB S Stage V sporulation protein AB
BHKMAKMB_01351 7.4e-112 spoVAA S Stage V sporulation protein AA
BHKMAKMB_01352 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BHKMAKMB_01353 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
BHKMAKMB_01354 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
BHKMAKMB_01355 2.8e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
BHKMAKMB_01356 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BHKMAKMB_01357 1.2e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
BHKMAKMB_01358 2.6e-166 xerD L recombinase XerD
BHKMAKMB_01359 3.7e-37 S Protein of unknown function (DUF4227)
BHKMAKMB_01360 2.4e-80 fur P Belongs to the Fur family
BHKMAKMB_01361 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
BHKMAKMB_01362 2e-32 yqkK
BHKMAKMB_01363 5.5e-242 mleA 1.1.1.38 C malic enzyme
BHKMAKMB_01364 3.1e-235 mleN C Na H antiporter
BHKMAKMB_01365 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
BHKMAKMB_01366 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
BHKMAKMB_01367 4.5e-58 ansR K Transcriptional regulator
BHKMAKMB_01368 3e-223 yqxK 3.6.4.12 L DNA helicase
BHKMAKMB_01369 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
BHKMAKMB_01371 4.4e-169 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
BHKMAKMB_01372 4e-14 yqkE S Protein of unknown function (DUF3886)
BHKMAKMB_01373 2.4e-175 yqkD S COG1073 Hydrolases of the alpha beta superfamily
BHKMAKMB_01374 9.4e-39 yqkC S Protein of unknown function (DUF2552)
BHKMAKMB_01375 2.8e-54 yqkB S Belongs to the HesB IscA family
BHKMAKMB_01376 4.7e-196 yqkA K GrpB protein
BHKMAKMB_01377 8e-60 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
BHKMAKMB_01378 3.6e-87 yqjY K acetyltransferase
BHKMAKMB_01379 2.2e-49 S YolD-like protein
BHKMAKMB_01380 3.1e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BHKMAKMB_01382 5.2e-226 yqjV G Major Facilitator Superfamily
BHKMAKMB_01384 7.2e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
BHKMAKMB_01385 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
BHKMAKMB_01386 2.4e-264 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
BHKMAKMB_01387 3.5e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
BHKMAKMB_01388 3.4e-180 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
BHKMAKMB_01389 8.6e-148 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BHKMAKMB_01390 0.0 rocB E arginine degradation protein
BHKMAKMB_01391 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
BHKMAKMB_01392 9.6e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
BHKMAKMB_01393 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
BHKMAKMB_01394 1.6e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BHKMAKMB_01395 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BHKMAKMB_01396 7.3e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BHKMAKMB_01397 4.5e-24 yqzJ
BHKMAKMB_01398 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
BHKMAKMB_01399 3.6e-142 yqjF S Uncharacterized conserved protein (COG2071)
BHKMAKMB_01400 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
BHKMAKMB_01401 4.4e-291 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
BHKMAKMB_01402 2.2e-75 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
BHKMAKMB_01404 1.4e-98 yqjB S protein conserved in bacteria
BHKMAKMB_01405 1.1e-175 yqjA S Putative aromatic acid exporter C-terminal domain
BHKMAKMB_01406 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
BHKMAKMB_01407 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
BHKMAKMB_01408 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
BHKMAKMB_01409 9.3e-77 yqiW S Belongs to the UPF0403 family
BHKMAKMB_01410 8.8e-167 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
BHKMAKMB_01411 7.9e-208 norA EGP Major facilitator Superfamily
BHKMAKMB_01412 2.6e-152 bmrR K helix_turn_helix, mercury resistance
BHKMAKMB_01413 3.5e-233 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
BHKMAKMB_01414 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
BHKMAKMB_01415 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
BHKMAKMB_01416 3.4e-269 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
BHKMAKMB_01417 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
BHKMAKMB_01418 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
BHKMAKMB_01419 7.1e-156 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
BHKMAKMB_01420 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
BHKMAKMB_01421 4e-34 yqzF S Protein of unknown function (DUF2627)
BHKMAKMB_01422 7.1e-164 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BHKMAKMB_01423 5.7e-277 prpD 4.2.1.79 S 2-methylcitrate dehydratase
BHKMAKMB_01424 8.1e-210 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
BHKMAKMB_01425 1.8e-212 mmgC I acyl-CoA dehydrogenase
BHKMAKMB_01426 4.7e-157 hbdA 1.1.1.157 I Dehydrogenase
BHKMAKMB_01427 1.2e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
BHKMAKMB_01428 1.8e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
BHKMAKMB_01429 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
BHKMAKMB_01430 5.9e-27
BHKMAKMB_01431 1.3e-215 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
BHKMAKMB_01433 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
BHKMAKMB_01434 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
BHKMAKMB_01435 0.0 recN L May be involved in recombinational repair of damaged DNA
BHKMAKMB_01436 1.7e-78 argR K Regulates arginine biosynthesis genes
BHKMAKMB_01437 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
BHKMAKMB_01438 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BHKMAKMB_01439 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
BHKMAKMB_01440 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
BHKMAKMB_01441 2.2e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
BHKMAKMB_01442 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BHKMAKMB_01443 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BHKMAKMB_01444 2.1e-67 yqhY S protein conserved in bacteria
BHKMAKMB_01445 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
BHKMAKMB_01446 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
BHKMAKMB_01447 9.9e-91 spoIIIAH S SpoIIIAH-like protein
BHKMAKMB_01448 6.9e-103 spoIIIAG S stage III sporulation protein AG
BHKMAKMB_01449 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
BHKMAKMB_01450 1.3e-197 spoIIIAE S stage III sporulation protein AE
BHKMAKMB_01451 2.3e-58 spoIIIAD S Stage III sporulation protein AD
BHKMAKMB_01452 7.6e-29 spoIIIAC S stage III sporulation protein AC
BHKMAKMB_01453 2.9e-85 spoIIIAB S Stage III sporulation protein
BHKMAKMB_01454 1.2e-171 spoIIIAA S stage III sporulation protein AA
BHKMAKMB_01455 7.9e-37 yqhV S Protein of unknown function (DUF2619)
BHKMAKMB_01456 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BHKMAKMB_01457 8.9e-174 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
BHKMAKMB_01458 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
BHKMAKMB_01459 2.3e-93 yqhR S Conserved membrane protein YqhR
BHKMAKMB_01460 9.4e-175 yqhQ S Protein of unknown function (DUF1385)
BHKMAKMB_01461 2.2e-61 yqhP
BHKMAKMB_01462 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
BHKMAKMB_01463 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
BHKMAKMB_01464 5.2e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
BHKMAKMB_01465 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
BHKMAKMB_01466 2.8e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BHKMAKMB_01467 3.4e-255 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BHKMAKMB_01468 9.6e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
BHKMAKMB_01469 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
BHKMAKMB_01470 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
BHKMAKMB_01471 1.2e-24 sinI S Anti-repressor SinI
BHKMAKMB_01472 1e-54 sinR K transcriptional
BHKMAKMB_01473 2.3e-142 tasA S Cell division protein FtsN
BHKMAKMB_01474 6.7e-59 sipW 3.4.21.89 U Signal peptidase
BHKMAKMB_01475 2.1e-116 yqxM
BHKMAKMB_01476 7.3e-54 yqzG S Protein of unknown function (DUF3889)
BHKMAKMB_01477 1.4e-26 yqzE S YqzE-like protein
BHKMAKMB_01478 3.7e-42 S ComG operon protein 7
BHKMAKMB_01479 5.5e-49 comGF U Putative Competence protein ComGF
BHKMAKMB_01480 1.1e-59 comGE
BHKMAKMB_01481 4.4e-71 gspH NU protein transport across the cell outer membrane
BHKMAKMB_01482 1.4e-47 comGC U Required for transformation and DNA binding
BHKMAKMB_01483 1.6e-175 comGB NU COG1459 Type II secretory pathway, component PulF
BHKMAKMB_01484 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BHKMAKMB_01486 7.2e-175 corA P Mg2 transporter protein
BHKMAKMB_01487 5.2e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
BHKMAKMB_01488 1.7e-151 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
BHKMAKMB_01490 7.8e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
BHKMAKMB_01491 1.8e-37 yqgY S Protein of unknown function (DUF2626)
BHKMAKMB_01492 1.9e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
BHKMAKMB_01493 8.9e-23 yqgW S Protein of unknown function (DUF2759)
BHKMAKMB_01494 6.9e-50 yqgV S Thiamine-binding protein
BHKMAKMB_01495 2.7e-199 yqgU
BHKMAKMB_01496 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
BHKMAKMB_01497 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
BHKMAKMB_01498 5.2e-181 glcK 2.7.1.2 G Glucokinase
BHKMAKMB_01499 3.1e-33 yqgQ S Protein conserved in bacteria
BHKMAKMB_01500 1.4e-268 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
BHKMAKMB_01501 2.5e-09 yqgO
BHKMAKMB_01502 2.7e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BHKMAKMB_01503 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
BHKMAKMB_01504 3.2e-203 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
BHKMAKMB_01506 9.2e-51 yqzD
BHKMAKMB_01507 1.9e-75 yqzC S YceG-like family
BHKMAKMB_01508 9.8e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
BHKMAKMB_01509 6.4e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
BHKMAKMB_01510 4.4e-158 pstA P Phosphate transport system permease
BHKMAKMB_01511 1.3e-160 pstC P probably responsible for the translocation of the substrate across the membrane
BHKMAKMB_01512 5.3e-151 pstS P Phosphate
BHKMAKMB_01513 0.0 pbpA 3.4.16.4 M penicillin-binding protein
BHKMAKMB_01514 2.5e-231 yqgE EGP Major facilitator superfamily
BHKMAKMB_01515 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
BHKMAKMB_01516 4e-73 yqgC S protein conserved in bacteria
BHKMAKMB_01517 8.5e-134 yqgB S Protein of unknown function (DUF1189)
BHKMAKMB_01518 2.2e-75 yqgA
BHKMAKMB_01519 5.2e-47 yqfZ M LysM domain
BHKMAKMB_01520 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BHKMAKMB_01521 4.3e-62 yqfX S membrane
BHKMAKMB_01522 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
BHKMAKMB_01523 1.9e-77 zur P Belongs to the Fur family
BHKMAKMB_01524 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
BHKMAKMB_01525 2.1e-36 yqfT S Protein of unknown function (DUF2624)
BHKMAKMB_01526 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BHKMAKMB_01527 1.7e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
BHKMAKMB_01528 2.9e-14 yqfQ S YqfQ-like protein
BHKMAKMB_01529 2.6e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BHKMAKMB_01530 5.1e-212 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BHKMAKMB_01531 6.1e-117 trmK 2.1.1.217 S SAM-dependent methyltransferase
BHKMAKMB_01532 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
BHKMAKMB_01533 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
BHKMAKMB_01534 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
BHKMAKMB_01535 4.5e-88 yaiI S Belongs to the UPF0178 family
BHKMAKMB_01536 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
BHKMAKMB_01537 4.5e-112 ccpN K CBS domain
BHKMAKMB_01538 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
BHKMAKMB_01539 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
BHKMAKMB_01540 4.8e-145 recO L Involved in DNA repair and RecF pathway recombination
BHKMAKMB_01541 8.4e-19 S YqzL-like protein
BHKMAKMB_01542 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BHKMAKMB_01543 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
BHKMAKMB_01544 1.6e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
BHKMAKMB_01545 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BHKMAKMB_01546 0.0 yqfF S membrane-associated HD superfamily hydrolase
BHKMAKMB_01548 1.1e-175 phoH T Phosphate starvation-inducible protein PhoH
BHKMAKMB_01549 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
BHKMAKMB_01550 2.7e-45 yqfC S sporulation protein YqfC
BHKMAKMB_01551 6e-25 yqfB
BHKMAKMB_01552 4.3e-122 yqfA S UPF0365 protein
BHKMAKMB_01553 5.4e-229 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
BHKMAKMB_01554 2.5e-61 yqeY S Yqey-like protein
BHKMAKMB_01555 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
BHKMAKMB_01556 1.6e-158 yqeW P COG1283 Na phosphate symporter
BHKMAKMB_01557 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
BHKMAKMB_01558 1.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
BHKMAKMB_01559 5.4e-175 prmA J Methylates ribosomal protein L11
BHKMAKMB_01560 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
BHKMAKMB_01561 0.0 dnaK O Heat shock 70 kDa protein
BHKMAKMB_01562 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BHKMAKMB_01563 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
BHKMAKMB_01564 4.8e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
BHKMAKMB_01565 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
BHKMAKMB_01566 1e-54 yqxA S Protein of unknown function (DUF3679)
BHKMAKMB_01567 6.9e-223 spoIIP M stage II sporulation protein P
BHKMAKMB_01568 1.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BHKMAKMB_01569 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
BHKMAKMB_01570 1.1e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
BHKMAKMB_01571 4.1e-15 S YqzM-like protein
BHKMAKMB_01572 0.0 comEC S Competence protein ComEC
BHKMAKMB_01573 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
BHKMAKMB_01574 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
BHKMAKMB_01575 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BHKMAKMB_01576 2.9e-139 yqeM Q Methyltransferase
BHKMAKMB_01577 6.9e-62 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
BHKMAKMB_01578 7.4e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
BHKMAKMB_01579 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BHKMAKMB_01580 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
BHKMAKMB_01581 2.7e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BHKMAKMB_01582 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
BHKMAKMB_01583 5.3e-95 yqeG S hydrolase of the HAD superfamily
BHKMAKMB_01585 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
BHKMAKMB_01586 2.1e-137 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
BHKMAKMB_01587 4.7e-106 yqeD S SNARE associated Golgi protein
BHKMAKMB_01588 1.2e-171 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
BHKMAKMB_01589 2.3e-133 yqeB
BHKMAKMB_01590 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
BHKMAKMB_01591 6.4e-33 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BHKMAKMB_01592 6.1e-274 cisA2 L Recombinase
BHKMAKMB_01593 1.8e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
BHKMAKMB_01594 6e-183 arsB 1.20.4.1 P Arsenic resistance protein
BHKMAKMB_01595 2.8e-73 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
BHKMAKMB_01596 1.6e-54 arsR K ArsR family transcriptional regulator
BHKMAKMB_01597 1.1e-152 yqcI S YqcI/YcgG family
BHKMAKMB_01598 1.6e-96 S Tetratricopeptide repeat
BHKMAKMB_01601 3.8e-277 A Pre-toxin TG
BHKMAKMB_01602 1.1e-104 S Suppressor of fused protein (SUFU)
BHKMAKMB_01604 5e-60
BHKMAKMB_01606 1.1e-144 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
BHKMAKMB_01607 2.6e-68 S Bacteriophage holin family
BHKMAKMB_01608 4.8e-165 xepA
BHKMAKMB_01609 1.3e-23
BHKMAKMB_01610 4.1e-56 xkdW S XkdW protein
BHKMAKMB_01611 2e-221
BHKMAKMB_01612 9.6e-40
BHKMAKMB_01613 9.9e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
BHKMAKMB_01614 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
BHKMAKMB_01615 9.6e-71 xkdS S Protein of unknown function (DUF2634)
BHKMAKMB_01616 1.8e-38 xkdR S Protein of unknown function (DUF2577)
BHKMAKMB_01617 2.4e-181 yqbQ 3.2.1.96 G NLP P60 protein
BHKMAKMB_01618 9e-114 xkdP S Lysin motif
BHKMAKMB_01619 0.0 xkdO L Transglycosylase SLT domain
BHKMAKMB_01620 1.8e-67 S Phage XkdN-like tail assembly chaperone protein, TAC
BHKMAKMB_01622 3.6e-76 xkdM S Phage tail tube protein
BHKMAKMB_01623 5.5e-256 xkdK S Phage tail sheath C-terminal domain
BHKMAKMB_01624 3.2e-26
BHKMAKMB_01625 1.4e-77
BHKMAKMB_01626 4.3e-94 S Bacteriophage HK97-gp10, putative tail-component
BHKMAKMB_01627 6.7e-65 yqbH S Domain of unknown function (DUF3599)
BHKMAKMB_01628 2.1e-67 S Protein of unknown function (DUF3199)
BHKMAKMB_01629 3.6e-51 S YqbF, hypothetical protein domain
BHKMAKMB_01630 1.9e-167 xkdG S Phage capsid family
BHKMAKMB_01631 5.1e-128 yqbD 2.1.1.72 L Putative phage serine protease XkdF
BHKMAKMB_01632 2e-115
BHKMAKMB_01633 5.7e-169 S Phage Mu protein F like protein
BHKMAKMB_01634 5.9e-296 yqbA S portal protein
BHKMAKMB_01635 2.4e-253 S phage terminase, large subunit
BHKMAKMB_01636 6.3e-107 yqaS L DNA packaging
BHKMAKMB_01638 6.5e-81 L Transposase
BHKMAKMB_01639 1.6e-166
BHKMAKMB_01640 2.1e-31 yqaO S Phage-like element PBSX protein XtrA
BHKMAKMB_01641 7.2e-74 rusA L Endodeoxyribonuclease RusA
BHKMAKMB_01643 5.9e-168 xkdC L IstB-like ATP binding protein
BHKMAKMB_01644 4.7e-123 3.1.3.16 L DnaD domain protein
BHKMAKMB_01645 2.5e-155 recT L RecT family
BHKMAKMB_01646 1.5e-180 yqaJ L YqaJ-like viral recombinase domain
BHKMAKMB_01650 1.2e-103
BHKMAKMB_01652 6.5e-37 K Helix-turn-helix XRE-family like proteins
BHKMAKMB_01653 1.1e-56 K sequence-specific DNA binding
BHKMAKMB_01655 1e-101 adk 2.7.4.3 F adenylate kinase activity
BHKMAKMB_01656 1.4e-100 yqaB E IrrE N-terminal-like domain
BHKMAKMB_01657 1.8e-61 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BHKMAKMB_01658 2e-68 psiE S Protein PsiE homolog
BHKMAKMB_01659 9e-237 yrkQ T Histidine kinase
BHKMAKMB_01660 1.1e-127 T Transcriptional regulator
BHKMAKMB_01661 8.2e-224 yrkO P Protein of unknown function (DUF418)
BHKMAKMB_01662 6e-105 yrkN K Acetyltransferase (GNAT) family
BHKMAKMB_01663 1.5e-97 ywrO S Flavodoxin-like fold
BHKMAKMB_01664 2.8e-79 S Protein of unknown function with HXXEE motif
BHKMAKMB_01665 4.3e-117 yrkJ S membrane transporter protein
BHKMAKMB_01666 2.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
BHKMAKMB_01667 1.1e-219 yrkH P Rhodanese Homology Domain
BHKMAKMB_01668 1.7e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
BHKMAKMB_01669 5.1e-84 yrkE O DsrE/DsrF/DrsH-like family
BHKMAKMB_01670 7.8e-39 yrkD S protein conserved in bacteria
BHKMAKMB_01671 2.6e-108 yrkC G Cupin domain
BHKMAKMB_01672 4.8e-151 bltR K helix_turn_helix, mercury resistance
BHKMAKMB_01673 3.5e-211 blt EGP Major facilitator Superfamily
BHKMAKMB_01674 1.4e-83 bltD 2.3.1.57 K FR47-like protein
BHKMAKMB_01675 4.5e-236 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
BHKMAKMB_01676 2.1e-17 S YrzO-like protein
BHKMAKMB_01677 1.7e-171 yrdR EG EamA-like transporter family
BHKMAKMB_01678 5.9e-160 yrdQ K Transcriptional regulator
BHKMAKMB_01679 2e-199 trkA P Oxidoreductase
BHKMAKMB_01680 3.5e-158 czcD P COG1230 Co Zn Cd efflux system component
BHKMAKMB_01681 1.3e-66 yodA S tautomerase
BHKMAKMB_01682 7.7e-163 gltR K LysR substrate binding domain
BHKMAKMB_01684 1.5e-231 brnQ E Component of the transport system for branched-chain amino acids
BHKMAKMB_01685 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
BHKMAKMB_01686 3.3e-138 azlC E AzlC protein
BHKMAKMB_01687 2.2e-79 bkdR K helix_turn_helix ASNC type
BHKMAKMB_01688 4.1e-46 yrdF K ribonuclease inhibitor
BHKMAKMB_01689 4.1e-231 cypA C Cytochrome P450
BHKMAKMB_01691 3.1e-101 yrdC 3.5.1.19 Q Isochorismatase family
BHKMAKMB_01692 1.9e-57 S Protein of unknown function (DUF2568)
BHKMAKMB_01693 1.2e-91 yrdA S DinB family
BHKMAKMB_01694 7.6e-168 aadK G Streptomycin adenylyltransferase
BHKMAKMB_01695 1.5e-194 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
BHKMAKMB_01696 7.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
BHKMAKMB_01697 3e-125 yrpD S Domain of unknown function, YrpD
BHKMAKMB_01699 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
BHKMAKMB_01700 6.3e-96 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
BHKMAKMB_01701 4.5e-188 yrpG C Aldo/keto reductase family
BHKMAKMB_01702 9.5e-226 yraO C Citrate transporter
BHKMAKMB_01703 1.2e-163 yraN K Transcriptional regulator
BHKMAKMB_01704 2.4e-206 yraM S PrpF protein
BHKMAKMB_01706 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
BHKMAKMB_01707 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
BHKMAKMB_01708 3.2e-155 S Alpha beta hydrolase
BHKMAKMB_01709 1.7e-60 T sh3 domain protein
BHKMAKMB_01710 2.4e-61 T sh3 domain protein
BHKMAKMB_01711 1.3e-66 E Glyoxalase-like domain
BHKMAKMB_01712 5.3e-37 yraG
BHKMAKMB_01713 6.4e-63 yraF M Spore coat protein
BHKMAKMB_01714 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
BHKMAKMB_01715 2.6e-26 yraE
BHKMAKMB_01716 1.1e-49 yraD M Spore coat protein
BHKMAKMB_01717 4.3e-47 yraB K helix_turn_helix, mercury resistance
BHKMAKMB_01718 3.2e-29 yphJ 4.1.1.44 S peroxiredoxin activity
BHKMAKMB_01719 1.9e-200 adhA 1.1.1.1 C alcohol dehydrogenase
BHKMAKMB_01720 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
BHKMAKMB_01721 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
BHKMAKMB_01722 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
BHKMAKMB_01723 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
BHKMAKMB_01724 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
BHKMAKMB_01725 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
BHKMAKMB_01726 0.0 levR K PTS system fructose IIA component
BHKMAKMB_01727 1.6e-255 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
BHKMAKMB_01728 3.6e-106 yrhP E LysE type translocator
BHKMAKMB_01729 1.1e-150 yrhO K Archaeal transcriptional regulator TrmB
BHKMAKMB_01730 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
BHKMAKMB_01731 1.7e-151 rsiV S Protein of unknown function (DUF3298)
BHKMAKMB_01732 0.0 yrhL I Acyltransferase family
BHKMAKMB_01733 1.5e-46 yrhK S YrhK-like protein
BHKMAKMB_01734 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
BHKMAKMB_01735 4.8e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
BHKMAKMB_01736 4.5e-97 yrhH Q methyltransferase
BHKMAKMB_01739 1.8e-142 focA P Formate nitrite
BHKMAKMB_01740 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
BHKMAKMB_01741 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
BHKMAKMB_01742 1.4e-78 yrhD S Protein of unknown function (DUF1641)
BHKMAKMB_01743 4.6e-35 yrhC S YrhC-like protein
BHKMAKMB_01744 2.6e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
BHKMAKMB_01745 1.2e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
BHKMAKMB_01746 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BHKMAKMB_01747 1.2e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
BHKMAKMB_01748 7e-27 yrzA S Protein of unknown function (DUF2536)
BHKMAKMB_01749 4.2e-63 yrrS S Protein of unknown function (DUF1510)
BHKMAKMB_01750 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
BHKMAKMB_01751 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
BHKMAKMB_01752 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
BHKMAKMB_01753 2.7e-246 yegQ O COG0826 Collagenase and related proteases
BHKMAKMB_01754 7.8e-174 yegQ O Peptidase U32
BHKMAKMB_01755 5.9e-120 yrrM 2.1.1.104 S O-methyltransferase
BHKMAKMB_01756 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BHKMAKMB_01757 1.2e-45 yrzB S Belongs to the UPF0473 family
BHKMAKMB_01758 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BHKMAKMB_01759 1.7e-41 yrzL S Belongs to the UPF0297 family
BHKMAKMB_01760 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BHKMAKMB_01761 2.7e-170 yrrI S AI-2E family transporter
BHKMAKMB_01762 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
BHKMAKMB_01763 5.1e-145 glnH ET Belongs to the bacterial solute-binding protein 3 family
BHKMAKMB_01764 3.6e-109 gluC P ABC transporter
BHKMAKMB_01765 7.6e-107 glnP P ABC transporter
BHKMAKMB_01766 8e-08 S Protein of unknown function (DUF3918)
BHKMAKMB_01767 9.8e-31 yrzR
BHKMAKMB_01768 1.8e-83 yrrD S protein conserved in bacteria
BHKMAKMB_01769 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
BHKMAKMB_01770 1.4e-15 S COG0457 FOG TPR repeat
BHKMAKMB_01771 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
BHKMAKMB_01772 4.7e-213 iscS 2.8.1.7 E Cysteine desulfurase
BHKMAKMB_01773 1.2e-70 cymR K Transcriptional regulator
BHKMAKMB_01774 2e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
BHKMAKMB_01775 2.8e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
BHKMAKMB_01776 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BHKMAKMB_01777 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
BHKMAKMB_01779 3.9e-263 lytH 3.5.1.28 M COG3103 SH3 domain protein
BHKMAKMB_01780 1.9e-68 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
BHKMAKMB_01781 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BHKMAKMB_01782 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BHKMAKMB_01783 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
BHKMAKMB_01784 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
BHKMAKMB_01785 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
BHKMAKMB_01786 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BHKMAKMB_01787 9.4e-49 yrzD S Post-transcriptional regulator
BHKMAKMB_01788 5.7e-270 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
BHKMAKMB_01789 2.2e-114 yrbG S membrane
BHKMAKMB_01790 1.2e-74 yrzE S Protein of unknown function (DUF3792)
BHKMAKMB_01791 1.1e-38 yajC U Preprotein translocase subunit YajC
BHKMAKMB_01792 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
BHKMAKMB_01793 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BHKMAKMB_01794 2.6e-18 yrzS S Protein of unknown function (DUF2905)
BHKMAKMB_01795 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
BHKMAKMB_01796 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
BHKMAKMB_01797 4.8e-93 bofC S BofC C-terminal domain
BHKMAKMB_01798 5.3e-253 csbX EGP Major facilitator Superfamily
BHKMAKMB_01799 1.3e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
BHKMAKMB_01800 6.5e-119 yrzF T serine threonine protein kinase
BHKMAKMB_01802 2.6e-35 S Family of unknown function (DUF5412)
BHKMAKMB_01803 1.8e-262 alsT E Sodium alanine symporter
BHKMAKMB_01804 1.9e-127 yebC K transcriptional regulatory protein
BHKMAKMB_01805 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
BHKMAKMB_01806 9.8e-158 safA M spore coat assembly protein SafA
BHKMAKMB_01807 2.8e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BHKMAKMB_01808 5.4e-161 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
BHKMAKMB_01809 2.7e-307 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
BHKMAKMB_01810 1.2e-230 nifS 2.8.1.7 E Cysteine desulfurase
BHKMAKMB_01811 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
BHKMAKMB_01812 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
BHKMAKMB_01813 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
BHKMAKMB_01814 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BHKMAKMB_01815 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
BHKMAKMB_01816 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
BHKMAKMB_01817 4.1e-56 ysxB J ribosomal protein
BHKMAKMB_01818 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
BHKMAKMB_01819 9.2e-161 spoIVFB S Stage IV sporulation protein
BHKMAKMB_01820 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
BHKMAKMB_01821 2.5e-144 minD D Belongs to the ParA family
BHKMAKMB_01822 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
BHKMAKMB_01823 1.4e-84 mreD M shape-determining protein
BHKMAKMB_01824 2.8e-157 mreC M Involved in formation and maintenance of cell shape
BHKMAKMB_01825 1.8e-184 mreB D Rod shape-determining protein MreB
BHKMAKMB_01826 5.9e-126 radC E Belongs to the UPF0758 family
BHKMAKMB_01827 2.8e-102 maf D septum formation protein Maf
BHKMAKMB_01828 1.1e-168 spoIIB S Sporulation related domain
BHKMAKMB_01829 6.6e-85 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
BHKMAKMB_01830 4.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
BHKMAKMB_01831 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
BHKMAKMB_01832 1.6e-25
BHKMAKMB_01833 1.6e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BHKMAKMB_01834 1.9e-226 spoVID M stage VI sporulation protein D
BHKMAKMB_01835 4.6e-249 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
BHKMAKMB_01836 5.6e-183 hemB 4.2.1.24 H Belongs to the ALAD family
BHKMAKMB_01837 4.4e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
BHKMAKMB_01838 3e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
BHKMAKMB_01839 3.6e-146 hemX O cytochrome C
BHKMAKMB_01840 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BHKMAKMB_01841 1.4e-89 ysxD
BHKMAKMB_01842 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
BHKMAKMB_01843 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BHKMAKMB_01844 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
BHKMAKMB_01845 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BHKMAKMB_01846 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
BHKMAKMB_01847 2.3e-187 ysoA H Tetratricopeptide repeat
BHKMAKMB_01848 8.1e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BHKMAKMB_01849 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BHKMAKMB_01850 3.3e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
BHKMAKMB_01851 4e-292 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BHKMAKMB_01852 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BHKMAKMB_01853 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
BHKMAKMB_01854 0.0 ilvB 2.2.1.6 E Acetolactate synthase
BHKMAKMB_01856 7.6e-82 ysnE K acetyltransferase
BHKMAKMB_01857 9.1e-134 ysnF S protein conserved in bacteria
BHKMAKMB_01859 1.4e-92 ysnB S Phosphoesterase
BHKMAKMB_01860 4.5e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BHKMAKMB_01861 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BHKMAKMB_01862 2.9e-196 gerM S COG5401 Spore germination protein
BHKMAKMB_01863 2.1e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
BHKMAKMB_01864 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
BHKMAKMB_01865 3.3e-30 gerE K Transcriptional regulator
BHKMAKMB_01866 7.7e-79 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
BHKMAKMB_01867 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
BHKMAKMB_01868 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
BHKMAKMB_01869 2.4e-107 sdhC C succinate dehydrogenase
BHKMAKMB_01870 1.2e-79 yslB S Protein of unknown function (DUF2507)
BHKMAKMB_01871 1.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
BHKMAKMB_01872 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
BHKMAKMB_01873 2e-52 trxA O Belongs to the thioredoxin family
BHKMAKMB_01874 4e-305 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
BHKMAKMB_01876 4.2e-178 etfA C Electron transfer flavoprotein
BHKMAKMB_01877 1.2e-135 etfB C Electron transfer flavoprotein
BHKMAKMB_01878 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
BHKMAKMB_01879 2.7e-100 fadR K Transcriptional regulator
BHKMAKMB_01880 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
BHKMAKMB_01881 7.3e-68 yshE S membrane
BHKMAKMB_01882 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
BHKMAKMB_01883 0.0 polX L COG1796 DNA polymerase IV (family X)
BHKMAKMB_01884 1.3e-85 cvpA S membrane protein, required for colicin V production
BHKMAKMB_01885 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BHKMAKMB_01886 4e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BHKMAKMB_01887 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
BHKMAKMB_01888 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BHKMAKMB_01889 3.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BHKMAKMB_01890 2.6e-32 sspI S Belongs to the SspI family
BHKMAKMB_01891 4.4e-208 ysfB KT regulator
BHKMAKMB_01892 7.2e-264 glcD 1.1.3.15 C Glycolate oxidase subunit
BHKMAKMB_01893 5.6e-258 glcF C Glycolate oxidase
BHKMAKMB_01894 3.6e-38 ysfE 4.4.1.5 E lactoylglutathione lyase activity
BHKMAKMB_01896 0.0 cstA T Carbon starvation protein
BHKMAKMB_01897 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
BHKMAKMB_01898 3.4e-144 araQ G transport system permease
BHKMAKMB_01899 1.4e-167 araP G carbohydrate transport
BHKMAKMB_01900 2.8e-254 araN G carbohydrate transport
BHKMAKMB_01901 5e-226 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
BHKMAKMB_01902 4.1e-147 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
BHKMAKMB_01903 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
BHKMAKMB_01904 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
BHKMAKMB_01905 1.9e-294 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
BHKMAKMB_01906 2.1e-190 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
BHKMAKMB_01907 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
BHKMAKMB_01908 9.2e-68 ysdB S Sigma-w pathway protein YsdB
BHKMAKMB_01909 7.5e-45 ysdA S Membrane
BHKMAKMB_01910 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BHKMAKMB_01911 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
BHKMAKMB_01912 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BHKMAKMB_01914 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
BHKMAKMB_01915 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
BHKMAKMB_01916 6.3e-131 lytT T COG3279 Response regulator of the LytR AlgR family
BHKMAKMB_01917 0.0 lytS 2.7.13.3 T Histidine kinase
BHKMAKMB_01918 1.5e-149 ysaA S HAD-hyrolase-like
BHKMAKMB_01919 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BHKMAKMB_01920 3.8e-159 ytxC S YtxC-like family
BHKMAKMB_01921 4.9e-111 ytxB S SNARE associated Golgi protein
BHKMAKMB_01922 3e-173 dnaI L Primosomal protein DnaI
BHKMAKMB_01923 3.5e-266 dnaB L Membrane attachment protein
BHKMAKMB_01924 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BHKMAKMB_01925 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BHKMAKMB_01926 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
BHKMAKMB_01927 9.9e-67 ytcD K Transcriptional regulator
BHKMAKMB_01928 4.9e-205 ytbD EGP Major facilitator Superfamily
BHKMAKMB_01929 8.9e-161 ytbE S reductase
BHKMAKMB_01930 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BHKMAKMB_01931 1.1e-107 ytaF P Probably functions as a manganese efflux pump
BHKMAKMB_01932 2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
BHKMAKMB_01933 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BHKMAKMB_01934 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
BHKMAKMB_01935 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BHKMAKMB_01936 1.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
BHKMAKMB_01937 1.8e-242 icd 1.1.1.42 C isocitrate
BHKMAKMB_01938 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
BHKMAKMB_01939 4.7e-71 yeaL S membrane
BHKMAKMB_01940 2.6e-192 ytvI S sporulation integral membrane protein YtvI
BHKMAKMB_01941 1.8e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
BHKMAKMB_01942 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
BHKMAKMB_01943 3.4e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
BHKMAKMB_01944 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
BHKMAKMB_01945 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BHKMAKMB_01946 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
BHKMAKMB_01947 0.0 dnaE 2.7.7.7 L DNA polymerase
BHKMAKMB_01948 3.2e-56 ytrH S Sporulation protein YtrH
BHKMAKMB_01949 8.2e-69 ytrI
BHKMAKMB_01950 9.2e-29
BHKMAKMB_01951 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
BHKMAKMB_01952 2.4e-47 ytpI S YtpI-like protein
BHKMAKMB_01953 8e-241 ytoI K transcriptional regulator containing CBS domains
BHKMAKMB_01954 1.2e-158 ytnM S membrane transporter protein
BHKMAKMB_01955 4.9e-240 ytnL 3.5.1.47 E hydrolase activity
BHKMAKMB_01956 6.3e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
BHKMAKMB_01957 1e-256 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BHKMAKMB_01958 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
BHKMAKMB_01959 1.2e-185 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BHKMAKMB_01960 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
BHKMAKMB_01961 7.6e-121 tcyM U Binding-protein-dependent transport system inner membrane component
BHKMAKMB_01962 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
BHKMAKMB_01963 1.5e-149 tcyK M Bacterial periplasmic substrate-binding proteins
BHKMAKMB_01964 9.5e-152 tcyK ET Bacterial periplasmic substrate-binding proteins
BHKMAKMB_01965 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
BHKMAKMB_01966 2.9e-173 ytlI K LysR substrate binding domain
BHKMAKMB_01967 1.7e-130 ytkL S Belongs to the UPF0173 family
BHKMAKMB_01968 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
BHKMAKMB_01970 3.1e-267 argH 4.3.2.1 E argininosuccinate lyase
BHKMAKMB_01971 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
BHKMAKMB_01972 3.6e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
BHKMAKMB_01973 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BHKMAKMB_01974 7e-165 ytxK 2.1.1.72 L DNA methylase
BHKMAKMB_01975 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BHKMAKMB_01976 8.7e-70 ytfJ S Sporulation protein YtfJ
BHKMAKMB_01977 5.6e-116 ytfI S Protein of unknown function (DUF2953)
BHKMAKMB_01978 1.3e-87 yteJ S RDD family
BHKMAKMB_01979 2.4e-181 sppA OU signal peptide peptidase SppA
BHKMAKMB_01980 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BHKMAKMB_01981 0.0 ytcJ S amidohydrolase
BHKMAKMB_01982 2e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
BHKMAKMB_01983 2e-29 sspB S spore protein
BHKMAKMB_01984 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BHKMAKMB_01985 2.2e-210 iscS2 2.8.1.7 E Cysteine desulfurase
BHKMAKMB_01986 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
BHKMAKMB_01987 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BHKMAKMB_01988 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
BHKMAKMB_01989 3.4e-109 yttP K Transcriptional regulator
BHKMAKMB_01990 1.2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
BHKMAKMB_01991 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
BHKMAKMB_01992 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BHKMAKMB_01994 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BHKMAKMB_01995 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
BHKMAKMB_01996 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
BHKMAKMB_01997 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
BHKMAKMB_01998 1.9e-225 acuC BQ histone deacetylase
BHKMAKMB_01999 1.4e-125 motS N Flagellar motor protein
BHKMAKMB_02000 7.1e-147 motA N flagellar motor
BHKMAKMB_02001 1.7e-182 ccpA K catabolite control protein A
BHKMAKMB_02002 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
BHKMAKMB_02003 4.4e-55 ytxJ O Protein of unknown function (DUF2847)
BHKMAKMB_02004 6.6e-17 ytxH S COG4980 Gas vesicle protein
BHKMAKMB_02005 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BHKMAKMB_02006 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
BHKMAKMB_02007 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
BHKMAKMB_02008 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
BHKMAKMB_02009 9.8e-149 ytpQ S Belongs to the UPF0354 family
BHKMAKMB_02010 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
BHKMAKMB_02011 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
BHKMAKMB_02012 4.7e-207 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
BHKMAKMB_02013 9.8e-52 ytzB S small secreted protein
BHKMAKMB_02014 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
BHKMAKMB_02015 6.4e-151 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
BHKMAKMB_02016 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
BHKMAKMB_02017 2e-45 ytzH S YtzH-like protein
BHKMAKMB_02018 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
BHKMAKMB_02019 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
BHKMAKMB_02020 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
BHKMAKMB_02021 1.3e-165 ytlQ
BHKMAKMB_02022 4.3e-103 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BHKMAKMB_02023 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
BHKMAKMB_02024 7.1e-272 pepV 3.5.1.18 E Dipeptidase
BHKMAKMB_02025 7.2e-226 pbuO S permease
BHKMAKMB_02026 3.9e-207 ythQ U Bacterial ABC transporter protein EcsB
BHKMAKMB_02027 4.3e-132 ythP V ABC transporter
BHKMAKMB_02028 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
BHKMAKMB_02029 2.6e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
BHKMAKMB_02030 1.9e-281 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
BHKMAKMB_02031 8.2e-232 ytfP S HI0933-like protein
BHKMAKMB_02032 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
BHKMAKMB_02033 3.1e-26 yteV S Sporulation protein Cse60
BHKMAKMB_02034 4.8e-117 yteU S Integral membrane protein
BHKMAKMB_02035 9.2e-258 yteT S Oxidoreductase family, C-terminal alpha/beta domain
BHKMAKMB_02036 4.6e-73 yteS G transport
BHKMAKMB_02037 4.7e-226 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
BHKMAKMB_02038 2e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
BHKMAKMB_02039 0.0 ytdP K Transcriptional regulator
BHKMAKMB_02040 1.2e-290 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
BHKMAKMB_02041 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
BHKMAKMB_02042 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
BHKMAKMB_02043 1.9e-225 bioI 1.14.14.46 C Cytochrome P450
BHKMAKMB_02044 2.2e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BHKMAKMB_02045 3.7e-128 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BHKMAKMB_02046 1.4e-220 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
BHKMAKMB_02047 2.4e-261 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
BHKMAKMB_02048 1.6e-142 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
BHKMAKMB_02049 1.3e-173 ytaP S Acetyl xylan esterase (AXE1)
BHKMAKMB_02050 2.3e-190 msmR K Transcriptional regulator
BHKMAKMB_02051 2.3e-248 msmE G Bacterial extracellular solute-binding protein
BHKMAKMB_02052 1.5e-169 amyD P ABC transporter
BHKMAKMB_02053 1.5e-144 amyC P ABC transporter (permease)
BHKMAKMB_02054 4e-253 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
BHKMAKMB_02055 2.1e-51 ytwF P Sulfurtransferase
BHKMAKMB_02056 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
BHKMAKMB_02057 7.7e-55 ytvB S Protein of unknown function (DUF4257)
BHKMAKMB_02058 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
BHKMAKMB_02059 2.1e-211 yttB EGP Major facilitator Superfamily
BHKMAKMB_02060 1.8e-43 yttA 2.7.13.3 S Pfam Transposase IS66
BHKMAKMB_02061 0.0 bceB V ABC transporter (permease)
BHKMAKMB_02062 1.1e-138 bceA V ABC transporter, ATP-binding protein
BHKMAKMB_02063 5.6e-186 T PhoQ Sensor
BHKMAKMB_02064 5.2e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BHKMAKMB_02065 8.5e-235 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
BHKMAKMB_02066 3.1e-127 ytrE V ABC transporter, ATP-binding protein
BHKMAKMB_02067 5.9e-148
BHKMAKMB_02068 6.1e-169 P ABC-2 family transporter protein
BHKMAKMB_02069 1.1e-161 ytrB P abc transporter atp-binding protein
BHKMAKMB_02070 5.1e-66 ytrA K GntR family transcriptional regulator
BHKMAKMB_02072 6.7e-41 ytzC S Protein of unknown function (DUF2524)
BHKMAKMB_02073 2.1e-190 yhcC S Fe-S oxidoreductase
BHKMAKMB_02074 3.3e-106 ytqB J Putative rRNA methylase
BHKMAKMB_02075 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
BHKMAKMB_02076 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
BHKMAKMB_02077 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BHKMAKMB_02078 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
BHKMAKMB_02079 0.0 asnB 6.3.5.4 E Asparagine synthase
BHKMAKMB_02080 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BHKMAKMB_02081 2.2e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BHKMAKMB_02082 1.2e-38 ytmB S Protein of unknown function (DUF2584)
BHKMAKMB_02083 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
BHKMAKMB_02084 5e-190 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
BHKMAKMB_02085 1.4e-144 ytlC P ABC transporter
BHKMAKMB_02086 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
BHKMAKMB_02087 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
BHKMAKMB_02088 5.4e-63 ytkC S Bacteriophage holin family
BHKMAKMB_02089 2.1e-76 dps P Belongs to the Dps family
BHKMAKMB_02091 3.6e-73 ytkA S YtkA-like
BHKMAKMB_02092 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
BHKMAKMB_02093 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
BHKMAKMB_02094 3.6e-41 rpmE2 J Ribosomal protein L31
BHKMAKMB_02095 4.7e-249 cydA 1.10.3.14 C oxidase, subunit
BHKMAKMB_02096 7.3e-189 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
BHKMAKMB_02097 1.1e-24 S Domain of Unknown Function (DUF1540)
BHKMAKMB_02098 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
BHKMAKMB_02099 3.2e-234 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
BHKMAKMB_02100 1.2e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
BHKMAKMB_02101 1.8e-170 troA P Belongs to the bacterial solute-binding protein 9 family
BHKMAKMB_02102 1.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
BHKMAKMB_02103 2.4e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
BHKMAKMB_02104 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BHKMAKMB_02105 3.8e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
BHKMAKMB_02106 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BHKMAKMB_02107 8.5e-273 menF 5.4.4.2 HQ Isochorismate synthase
BHKMAKMB_02108 2.6e-132 dksA T COG1734 DnaK suppressor protein
BHKMAKMB_02109 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
BHKMAKMB_02110 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BHKMAKMB_02111 3.9e-181 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
BHKMAKMB_02112 3.6e-235 ytcC M Glycosyltransferase Family 4
BHKMAKMB_02114 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
BHKMAKMB_02115 1.8e-217 cotSA M Glycosyl transferases group 1
BHKMAKMB_02116 1.8e-206 cotI S Spore coat protein
BHKMAKMB_02117 9.9e-77 tspO T membrane
BHKMAKMB_02118 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
BHKMAKMB_02119 4.3e-288 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
BHKMAKMB_02120 1.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
BHKMAKMB_02121 3.6e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BHKMAKMB_02122 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BHKMAKMB_02131 7.8e-08
BHKMAKMB_02132 1.3e-09
BHKMAKMB_02139 2e-08
BHKMAKMB_02146 5.5e-37 S COG NOG14552 non supervised orthologous group
BHKMAKMB_02149 1.1e-16 ydhU P Manganese containing catalase
BHKMAKMB_02150 8.7e-78 ydhU P Catalase
BHKMAKMB_02151 1.8e-214 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
BHKMAKMB_02152 4.2e-191 manA 5.3.1.8 G mannose-6-phosphate isomerase
BHKMAKMB_02153 9.2e-172 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
BHKMAKMB_02154 3.9e-133 ydhQ K UTRA
BHKMAKMB_02155 2.4e-288 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
BHKMAKMB_02156 2e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
BHKMAKMB_02157 3.5e-52 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
BHKMAKMB_02158 1.1e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
BHKMAKMB_02159 4.6e-200 pbuE EGP Major facilitator Superfamily
BHKMAKMB_02160 1.7e-99 ydhK M Protein of unknown function (DUF1541)
BHKMAKMB_02161 1.8e-184 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
BHKMAKMB_02162 4.1e-86 K Acetyltransferase (GNAT) domain
BHKMAKMB_02164 4.6e-69 frataxin S Domain of unknown function (DU1801)
BHKMAKMB_02165 1.4e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
BHKMAKMB_02166 1.9e-127
BHKMAKMB_02167 7e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
BHKMAKMB_02168 3.3e-244 ydhD M Glycosyl hydrolase
BHKMAKMB_02169 6.5e-122 ydhC K FCD
BHKMAKMB_02170 1.2e-121 ydhB S membrane transporter protein
BHKMAKMB_02171 2.5e-209 tcaB EGP Major facilitator Superfamily
BHKMAKMB_02172 1.1e-69 ydgJ K Winged helix DNA-binding domain
BHKMAKMB_02173 1e-113 drgA C nitroreductase
BHKMAKMB_02174 0.0 ydgH S drug exporters of the RND superfamily
BHKMAKMB_02175 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
BHKMAKMB_02176 4.6e-91 dinB S DinB family
BHKMAKMB_02177 4e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
BHKMAKMB_02178 4.2e-308 expZ S ABC transporter
BHKMAKMB_02179 2.4e-86 yycN 2.3.1.128 K Acetyltransferase
BHKMAKMB_02180 1.9e-53 S DoxX-like family
BHKMAKMB_02181 1.5e-101 K Bacterial regulatory proteins, tetR family
BHKMAKMB_02182 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
BHKMAKMB_02183 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
BHKMAKMB_02184 1.7e-75 cotP O Belongs to the small heat shock protein (HSP20) family
BHKMAKMB_02185 5.2e-122 ydfS S Protein of unknown function (DUF421)
BHKMAKMB_02186 4.4e-118 ydfR S Protein of unknown function (DUF421)
BHKMAKMB_02188 6.3e-29
BHKMAKMB_02189 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
BHKMAKMB_02190 1.3e-57 traF CO Thioredoxin
BHKMAKMB_02191 8.8e-63 mhqP S DoxX
BHKMAKMB_02192 3.6e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
BHKMAKMB_02193 9.6e-112 ydfN C nitroreductase
BHKMAKMB_02194 1.6e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BHKMAKMB_02195 3.2e-147 K Bacterial transcription activator, effector binding domain
BHKMAKMB_02196 5.9e-118 S Protein of unknown function (DUF554)
BHKMAKMB_02197 1.9e-177 S Alpha/beta hydrolase family
BHKMAKMB_02198 0.0 ydfJ S drug exporters of the RND superfamily
BHKMAKMB_02199 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
BHKMAKMB_02200 5.3e-180 ydfH 2.7.13.3 T Histidine kinase
BHKMAKMB_02202 1.5e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BHKMAKMB_02203 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
BHKMAKMB_02204 5.9e-117 ydfE S Flavin reductase like domain
BHKMAKMB_02205 1.9e-275 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
BHKMAKMB_02206 1e-162 ydfC EG EamA-like transporter family
BHKMAKMB_02207 7.2e-149 ydfB J GNAT acetyltransferase
BHKMAKMB_02208 5.2e-232 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BHKMAKMB_02209 1.3e-57 arsR K transcriptional
BHKMAKMB_02210 8.4e-105 ydeS K Transcriptional regulator
BHKMAKMB_02211 1.2e-195 ydeR EGP Major facilitator Superfamily
BHKMAKMB_02212 1.6e-108 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
BHKMAKMB_02213 4.8e-69 ydeP K Transcriptional regulator
BHKMAKMB_02214 1.9e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
BHKMAKMB_02215 1.1e-58 K HxlR-like helix-turn-helix
BHKMAKMB_02216 8.6e-107 ydeN S Serine hydrolase
BHKMAKMB_02217 4.2e-74 maoC I N-terminal half of MaoC dehydratase
BHKMAKMB_02218 1.5e-274 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
BHKMAKMB_02219 1.8e-153 ydeK EG -transporter
BHKMAKMB_02220 4e-116
BHKMAKMB_02221 8.9e-107 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
BHKMAKMB_02222 2.9e-47 ydeH
BHKMAKMB_02223 3.4e-220 ydeG EGP Major facilitator superfamily
BHKMAKMB_02224 2.2e-265 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
BHKMAKMB_02225 2.5e-166 ydeE K AraC family transcriptional regulator
BHKMAKMB_02226 2.3e-173 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
BHKMAKMB_02227 1.1e-166 rhaS5 K AraC-like ligand binding domain
BHKMAKMB_02228 4.6e-35 ydzE EG spore germination
BHKMAKMB_02229 6.1e-79 carD K Transcription factor
BHKMAKMB_02230 8.7e-30 cspL K Cold shock
BHKMAKMB_02231 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
BHKMAKMB_02236 5e-227 ydeG EGP Major facilitator Superfamily
BHKMAKMB_02237 1.5e-143 yddR S Zn-dependent hydrolases of the beta-lactamase fold
BHKMAKMB_02238 9.6e-100 yddQ 3.5.1.19 Q Isochorismatase family
BHKMAKMB_02239 3.9e-78 lrpB K transcriptional
BHKMAKMB_02240 2.4e-71 lrpA K transcriptional
BHKMAKMB_02241 2.7e-188 luxA C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BHKMAKMB_02249 1.6e-84 ydcK S Belongs to the SprT family
BHKMAKMB_02250 0.0 yhgF K COG2183 Transcriptional accessory protein
BHKMAKMB_02251 1.6e-76 ydcH K helix_turn_helix multiple antibiotic resistance protein
BHKMAKMB_02252 1.5e-82 ydcG S EVE domain
BHKMAKMB_02256 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
BHKMAKMB_02257 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BHKMAKMB_02258 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
BHKMAKMB_02259 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
BHKMAKMB_02260 7.1e-189 rsbU 3.1.3.3 KT phosphatase
BHKMAKMB_02261 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
BHKMAKMB_02262 5.2e-57 rsbS T antagonist
BHKMAKMB_02263 1.3e-143 rsbR T Positive regulator of sigma-B
BHKMAKMB_02264 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
BHKMAKMB_02265 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
BHKMAKMB_02266 2.3e-223 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BHKMAKMB_02267 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
BHKMAKMB_02268 2.5e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
BHKMAKMB_02269 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
BHKMAKMB_02270 2.2e-263 ydbT S Membrane
BHKMAKMB_02271 2.1e-82 ydbS S Bacterial PH domain
BHKMAKMB_02272 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
BHKMAKMB_02273 1.9e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
BHKMAKMB_02274 4.6e-202 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
BHKMAKMB_02275 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
BHKMAKMB_02276 1.9e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BHKMAKMB_02277 2.2e-07 S Fur-regulated basic protein A
BHKMAKMB_02278 1.1e-18 S Fur-regulated basic protein B
BHKMAKMB_02279 3e-220 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
BHKMAKMB_02280 2.7e-52 ydbL
BHKMAKMB_02281 5.5e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
BHKMAKMB_02282 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
BHKMAKMB_02283 4.4e-181 ydbI S AI-2E family transporter
BHKMAKMB_02284 6.3e-227 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
BHKMAKMB_02285 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
BHKMAKMB_02286 2.5e-297 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
BHKMAKMB_02287 2.7e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
BHKMAKMB_02288 3.2e-155 ydbD P Catalase
BHKMAKMB_02289 2.8e-63 ydbC S Domain of unknown function (DUF4937
BHKMAKMB_02290 8.9e-59 ydbB G Cupin domain
BHKMAKMB_02292 3.8e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
BHKMAKMB_02293 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
BHKMAKMB_02295 1.6e-24 mntH P H( )-stimulated, divalent metal cation uptake system
BHKMAKMB_02296 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
BHKMAKMB_02297 6.8e-77 ydaG 1.4.3.5 S general stress protein
BHKMAKMB_02298 5e-104 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
BHKMAKMB_02299 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
BHKMAKMB_02300 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
BHKMAKMB_02301 1.1e-99 ydaC Q Methyltransferase domain
BHKMAKMB_02302 1.4e-294 ydaB IQ acyl-CoA ligase
BHKMAKMB_02303 0.0 mtlR K transcriptional regulator, MtlR
BHKMAKMB_02304 2.8e-176 ydhF S Oxidoreductase
BHKMAKMB_02305 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
BHKMAKMB_02306 1.4e-49 yczJ S biosynthesis
BHKMAKMB_02308 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
BHKMAKMB_02309 1.2e-132 kipR K Transcriptional regulator
BHKMAKMB_02310 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
BHKMAKMB_02311 1.9e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
BHKMAKMB_02312 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
BHKMAKMB_02313 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
BHKMAKMB_02314 1.2e-140 ycsF S Belongs to the UPF0271 (lamB) family
BHKMAKMB_02315 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
BHKMAKMB_02317 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
BHKMAKMB_02318 5e-113 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
BHKMAKMB_02319 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
BHKMAKMB_02320 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
BHKMAKMB_02321 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
BHKMAKMB_02322 7.3e-211 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
BHKMAKMB_02323 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
BHKMAKMB_02324 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
BHKMAKMB_02325 7.3e-56
BHKMAKMB_02326 1.7e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
BHKMAKMB_02327 1.4e-308 ycnJ P protein, homolog of Cu resistance protein CopC
BHKMAKMB_02328 1.3e-100 ycnI S protein conserved in bacteria
BHKMAKMB_02329 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
BHKMAKMB_02330 6.1e-149 glcU U Glucose uptake
BHKMAKMB_02331 3.4e-266 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
BHKMAKMB_02332 4.4e-247 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BHKMAKMB_02333 1.3e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
BHKMAKMB_02334 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
BHKMAKMB_02335 1.6e-45 ycnE S Monooxygenase
BHKMAKMB_02336 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
BHKMAKMB_02337 6.5e-154 ycnC K Transcriptional regulator
BHKMAKMB_02338 1.4e-251 ycnB EGP Major facilitator Superfamily
BHKMAKMB_02339 5.5e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
BHKMAKMB_02340 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
BHKMAKMB_02341 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BHKMAKMB_02342 1.6e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BHKMAKMB_02343 1.5e-253 lysC 2.7.2.4 E Belongs to the aspartokinase family
BHKMAKMB_02346 5.2e-71 S aspartate phosphatase
BHKMAKMB_02347 1.8e-262 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
BHKMAKMB_02348 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BHKMAKMB_02349 1.7e-204 yclI V ABC transporter (permease) YclI
BHKMAKMB_02350 3.9e-122 yclH P ABC transporter
BHKMAKMB_02351 9.9e-200 gerKB F Spore germination protein
BHKMAKMB_02352 1.3e-232 gerKC S spore germination
BHKMAKMB_02353 6.8e-282 gerKA EG Spore germination protein
BHKMAKMB_02355 2.9e-310 yclG M Pectate lyase superfamily protein
BHKMAKMB_02356 1.5e-267 dtpT E amino acid peptide transporter
BHKMAKMB_02357 6.2e-162 yclE 3.4.11.5 S Alpha beta hydrolase
BHKMAKMB_02358 1.1e-83 yclD
BHKMAKMB_02359 4e-39 bsdD 4.1.1.61 S response to toxic substance
BHKMAKMB_02360 1.8e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
BHKMAKMB_02361 2e-109 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
BHKMAKMB_02362 4.9e-162 bsdA K LysR substrate binding domain
BHKMAKMB_02363 1.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
BHKMAKMB_02364 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
BHKMAKMB_02365 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
BHKMAKMB_02366 4.4e-115 yczE S membrane
BHKMAKMB_02367 4.4e-75 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
BHKMAKMB_02368 4.4e-255 ycxD K GntR family transcriptional regulator
BHKMAKMB_02369 7.4e-164 ycxC EG EamA-like transporter family
BHKMAKMB_02370 4.9e-91 S YcxB-like protein
BHKMAKMB_02371 4.2e-228 EGP Major Facilitator Superfamily
BHKMAKMB_02372 5.7e-140 srfAD Q thioesterase
BHKMAKMB_02373 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
BHKMAKMB_02374 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
BHKMAKMB_02375 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
BHKMAKMB_02376 1.3e-63 hxlR K transcriptional
BHKMAKMB_02377 3.3e-107 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
BHKMAKMB_02378 4.6e-97 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
BHKMAKMB_02379 3e-187 tlpC 2.7.13.3 NT chemotaxis protein
BHKMAKMB_02380 3.2e-72 nucA M Deoxyribonuclease NucA/NucB
BHKMAKMB_02381 3.4e-70 nin S Competence protein J (ComJ)
BHKMAKMB_02382 1.2e-298 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
BHKMAKMB_02383 3.5e-52 yckD S Protein of unknown function (DUF2680)
BHKMAKMB_02384 3.3e-77 yckC S membrane
BHKMAKMB_02386 1.1e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
BHKMAKMB_02387 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
BHKMAKMB_02388 1.4e-228 yciC S GTPases (G3E family)
BHKMAKMB_02389 5.5e-109 yciB M ErfK YbiS YcfS YnhG
BHKMAKMB_02390 1.4e-172 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
BHKMAKMB_02391 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
BHKMAKMB_02392 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
BHKMAKMB_02393 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BHKMAKMB_02394 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BHKMAKMB_02395 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
BHKMAKMB_02396 9.3e-283 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
BHKMAKMB_02397 8.3e-190 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
BHKMAKMB_02398 5.7e-163 I alpha/beta hydrolase fold
BHKMAKMB_02399 1.2e-139 ycgR S permeases
BHKMAKMB_02400 2.6e-147 ycgQ S membrane
BHKMAKMB_02401 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
BHKMAKMB_02402 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BHKMAKMB_02403 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
BHKMAKMB_02404 5.1e-170 ycgM E Proline dehydrogenase
BHKMAKMB_02405 2.9e-145 ycgL S Predicted nucleotidyltransferase
BHKMAKMB_02406 2.9e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
BHKMAKMB_02407 2.2e-179 oxyR3 K LysR substrate binding domain
BHKMAKMB_02408 3.6e-145 yafE Q ubiE/COQ5 methyltransferase family
BHKMAKMB_02409 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BHKMAKMB_02410 2.5e-109 tmrB S AAA domain
BHKMAKMB_02411 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
BHKMAKMB_02412 2.4e-112 ycgI S Domain of unknown function (DUF1989)
BHKMAKMB_02413 5.6e-250 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
BHKMAKMB_02414 1.2e-151 yqcI S YqcI/YcgG family
BHKMAKMB_02415 6.8e-113 ycgF E Lysine exporter protein LysE YggA
BHKMAKMB_02416 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
BHKMAKMB_02417 6.2e-269 mdr EGP Major facilitator Superfamily
BHKMAKMB_02418 6.5e-293 lctP C L-lactate permease
BHKMAKMB_02419 3.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
BHKMAKMB_02420 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
BHKMAKMB_02421 1.1e-98 ycgB
BHKMAKMB_02422 1e-257 ycgA S Membrane
BHKMAKMB_02423 1.2e-219 amhX S amidohydrolase
BHKMAKMB_02424 5.3e-164 opuAC E glycine betaine
BHKMAKMB_02425 1.3e-127 opuAB P glycine betaine
BHKMAKMB_02426 5.1e-229 proV 3.6.3.32 E glycine betaine
BHKMAKMB_02427 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
BHKMAKMB_02428 1.9e-209 yceJ EGP Uncharacterised MFS-type transporter YbfB
BHKMAKMB_02429 1e-218 naiP P Uncharacterised MFS-type transporter YbfB
BHKMAKMB_02430 2e-192 yceH P Belongs to the TelA family
BHKMAKMB_02431 0.0 yceG S Putative component of 'biosynthetic module'
BHKMAKMB_02432 6.3e-137 terC P Protein of unknown function (DUF475)
BHKMAKMB_02433 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
BHKMAKMB_02434 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
BHKMAKMB_02435 3.9e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
BHKMAKMB_02436 5.4e-189 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BHKMAKMB_02437 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
BHKMAKMB_02438 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
BHKMAKMB_02439 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
BHKMAKMB_02440 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
BHKMAKMB_02441 1.6e-140 IQ Enoyl-(Acyl carrier protein) reductase
BHKMAKMB_02442 5.5e-174 S response regulator aspartate phosphatase
BHKMAKMB_02443 1.7e-95 cwlK M D-alanyl-D-alanine carboxypeptidase
BHKMAKMB_02444 6.7e-268 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
BHKMAKMB_02445 5.9e-282 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
BHKMAKMB_02446 6.6e-177 ycdA S Domain of unknown function (DUF5105)
BHKMAKMB_02447 1.6e-174 yccK C Aldo keto reductase
BHKMAKMB_02448 4.5e-203 natB CP ABC-2 family transporter protein
BHKMAKMB_02449 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
BHKMAKMB_02450 1.2e-126 lytR_2 T LytTr DNA-binding domain
BHKMAKMB_02451 2e-161 2.7.13.3 T GHKL domain
BHKMAKMB_02452 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
BHKMAKMB_02453 2e-59 S RDD family
BHKMAKMB_02454 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
BHKMAKMB_02455 2.2e-202 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
BHKMAKMB_02456 4.8e-102 yxaF K Transcriptional regulator
BHKMAKMB_02457 5.8e-229 lmrB EGP the major facilitator superfamily
BHKMAKMB_02458 2.3e-209 ycbU E Selenocysteine lyase
BHKMAKMB_02459 1.4e-121 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BHKMAKMB_02460 1.2e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BHKMAKMB_02461 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
BHKMAKMB_02462 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
BHKMAKMB_02463 6.6e-136 ycbR T vWA found in TerF C terminus
BHKMAKMB_02464 1.3e-78 sleB 3.5.1.28 M Cell wall
BHKMAKMB_02465 8.2e-53 ycbP S Protein of unknown function (DUF2512)
BHKMAKMB_02466 2.1e-115 S ABC-2 family transporter protein
BHKMAKMB_02467 4.8e-168 ycbN V ABC transporter, ATP-binding protein
BHKMAKMB_02468 2.4e-170 T PhoQ Sensor
BHKMAKMB_02469 1.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BHKMAKMB_02470 9.6e-172 eamA1 EG spore germination
BHKMAKMB_02471 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
BHKMAKMB_02472 1.8e-178 ycbJ S Macrolide 2'-phosphotransferase
BHKMAKMB_02473 3.7e-298 garD 4.2.1.42, 4.2.1.7 G Altronate
BHKMAKMB_02474 1.5e-124 ycbG K FCD
BHKMAKMB_02475 2.2e-270 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
BHKMAKMB_02476 1.2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
BHKMAKMB_02477 3.7e-274 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
BHKMAKMB_02478 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
BHKMAKMB_02479 9e-170 glnL T Regulator
BHKMAKMB_02480 1.5e-229 phoQ 2.7.13.3 T Histidine kinase
BHKMAKMB_02481 1.5e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
BHKMAKMB_02482 2.3e-257 agcS E Sodium alanine symporter
BHKMAKMB_02483 9.3e-183 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
BHKMAKMB_02484 6.7e-262 mmuP E amino acid
BHKMAKMB_02485 5.4e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
BHKMAKMB_02487 4.9e-128 K UTRA
BHKMAKMB_02488 2.1e-137 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
BHKMAKMB_02489 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
BHKMAKMB_02490 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
BHKMAKMB_02491 3.9e-192 yceA S Belongs to the UPF0176 family
BHKMAKMB_02492 6.7e-167 ybfP K Transcriptional regulator
BHKMAKMB_02493 4.3e-258 S Erythromycin esterase
BHKMAKMB_02494 3.2e-46 ybfN
BHKMAKMB_02495 5.6e-149 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
BHKMAKMB_02496 2.7e-85 ybfM S SNARE associated Golgi protein
BHKMAKMB_02497 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BHKMAKMB_02498 2.5e-169 S Alpha/beta hydrolase family
BHKMAKMB_02500 6.9e-178 mpr 3.4.21.19 M Belongs to the peptidase S1B family
BHKMAKMB_02501 1.9e-214 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BHKMAKMB_02502 2.3e-145 msmR K AraC-like ligand binding domain
BHKMAKMB_02503 8.8e-162 ybfH EG EamA-like transporter family
BHKMAKMB_02504 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
BHKMAKMB_02506 2.2e-224 ybfB G COG0477 Permeases of the major facilitator superfamily
BHKMAKMB_02507 1.6e-171 ybfA 3.4.15.5 K FR47-like protein
BHKMAKMB_02508 2.9e-35 S Protein of unknown function (DUF2651)
BHKMAKMB_02509 7.3e-258 glpT G -transporter
BHKMAKMB_02510 5.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
BHKMAKMB_02511 1.8e-290 ybeC E amino acid
BHKMAKMB_02512 4.9e-41 ybyB
BHKMAKMB_02513 1.4e-247 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
BHKMAKMB_02514 7.2e-152 ybxI 3.5.2.6 V beta-lactamase
BHKMAKMB_02515 4.9e-30 ybxH S Family of unknown function (DUF5370)
BHKMAKMB_02516 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
BHKMAKMB_02517 2.4e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
BHKMAKMB_02518 1.5e-217 ybdO S Domain of unknown function (DUF4885)
BHKMAKMB_02519 4.8e-154 ybdN
BHKMAKMB_02520 1.6e-140 KLT Protein tyrosine kinase
BHKMAKMB_02522 1.8e-173 T His Kinase A (phospho-acceptor) domain
BHKMAKMB_02523 1.5e-123 T Transcriptional regulatory protein, C terminal
BHKMAKMB_02524 6.2e-182 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
BHKMAKMB_02525 9.6e-79 txn CO Thioredoxin-like
BHKMAKMB_02526 7.8e-91 C HEAT repeats
BHKMAKMB_02527 4e-248 skfF S ABC transporter
BHKMAKMB_02528 1.9e-135 skfE V ABC transporter
BHKMAKMB_02529 1.6e-277 V CAAX protease self-immunity
BHKMAKMB_02530 9.1e-239 J 4Fe-4S single cluster domain
BHKMAKMB_02532 2e-203 ybcL EGP Major facilitator Superfamily
BHKMAKMB_02533 5.1e-50 ybzH K Helix-turn-helix domain
BHKMAKMB_02534 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
BHKMAKMB_02535 3.9e-47
BHKMAKMB_02536 3.7e-96 can 4.2.1.1 P carbonic anhydrase
BHKMAKMB_02537 0.0 ybcC S Belongs to the UPF0753 family
BHKMAKMB_02538 1.5e-278 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
BHKMAKMB_02539 5.1e-101 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BHKMAKMB_02540 1.4e-121 adaA 3.2.2.21 K Transcriptional regulator
BHKMAKMB_02541 2.1e-176 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BHKMAKMB_02542 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
BHKMAKMB_02543 9.3e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BHKMAKMB_02544 3e-225 ybbR S protein conserved in bacteria
BHKMAKMB_02545 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BHKMAKMB_02546 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
BHKMAKMB_02547 8.5e-99 sigW K Belongs to the sigma-70 factor family. ECF subfamily
BHKMAKMB_02553 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
BHKMAKMB_02554 6.4e-87 ybbJ J acetyltransferase
BHKMAKMB_02555 2.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BHKMAKMB_02556 1.1e-150 ybbH K transcriptional
BHKMAKMB_02557 9.8e-234 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
BHKMAKMB_02558 4e-256 yfeW 3.4.16.4 V Belongs to the UPF0214 family
BHKMAKMB_02559 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
BHKMAKMB_02560 4.4e-241 ybbC 3.2.1.52 S protein conserved in bacteria
BHKMAKMB_02561 5.4e-308 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
BHKMAKMB_02562 7.2e-167 feuA P Iron-uptake system-binding protein
BHKMAKMB_02563 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BHKMAKMB_02564 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BHKMAKMB_02565 2.2e-142 ybbA S Putative esterase
BHKMAKMB_02566 1.2e-161 ybaS 1.1.1.58 S Na -dependent transporter
BHKMAKMB_02568 4.6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
BHKMAKMB_02569 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
BHKMAKMB_02570 3.4e-94 M1-753 M FR47-like protein
BHKMAKMB_02571 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
BHKMAKMB_02572 1.4e-77 yuaF OU Membrane protein implicated in regulation of membrane protease activity
BHKMAKMB_02573 3.9e-84 yuaE S DinB superfamily
BHKMAKMB_02574 7.9e-108 yuaD
BHKMAKMB_02575 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
BHKMAKMB_02576 8e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
BHKMAKMB_02577 1.1e-95 yuaC K Belongs to the GbsR family
BHKMAKMB_02578 2.2e-91 yuaB
BHKMAKMB_02579 5e-122 ktrA P COG0569 K transport systems, NAD-binding component
BHKMAKMB_02580 5.4e-237 ktrB P Potassium
BHKMAKMB_02581 1e-38 yiaA S yiaA/B two helix domain
BHKMAKMB_02582 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
BHKMAKMB_02583 6.2e-277 yubD P Major Facilitator Superfamily
BHKMAKMB_02584 2.6e-88 cdoA 1.13.11.20 S Cysteine dioxygenase type I
BHKMAKMB_02586 1.2e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
BHKMAKMB_02587 6.3e-197 yubA S transporter activity
BHKMAKMB_02588 3.3e-183 ygjR S Oxidoreductase
BHKMAKMB_02589 1.4e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
BHKMAKMB_02590 2.5e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
BHKMAKMB_02591 1.3e-281 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
BHKMAKMB_02592 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
BHKMAKMB_02593 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
BHKMAKMB_02594 5.1e-239 mcpA NT chemotaxis protein
BHKMAKMB_02595 2.2e-295 mcpA NT chemotaxis protein
BHKMAKMB_02596 1.5e-222 mcpA NT chemotaxis protein
BHKMAKMB_02597 3.2e-225 mcpA NT chemotaxis protein
BHKMAKMB_02598 2.6e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
BHKMAKMB_02599 1e-35
BHKMAKMB_02600 2.1e-72 yugU S Uncharacterised protein family UPF0047
BHKMAKMB_02601 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
BHKMAKMB_02602 2.6e-236 yugS S COG1253 Hemolysins and related proteins containing CBS domains
BHKMAKMB_02603 1.4e-116 yugP S Zn-dependent protease
BHKMAKMB_02604 4.6e-39
BHKMAKMB_02605 1.1e-53 mstX S Membrane-integrating protein Mistic
BHKMAKMB_02606 1.7e-182 yugO P COG1226 Kef-type K transport systems
BHKMAKMB_02607 1.3e-72 yugN S YugN-like family
BHKMAKMB_02609 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
BHKMAKMB_02610 2.8e-229 yugK C Dehydrogenase
BHKMAKMB_02611 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
BHKMAKMB_02612 1.1e-34 yuzA S Domain of unknown function (DUF378)
BHKMAKMB_02613 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
BHKMAKMB_02614 4.3e-200 yugH 2.6.1.1 E Aminotransferase
BHKMAKMB_02615 1.6e-85 alaR K Transcriptional regulator
BHKMAKMB_02616 1e-156 yugF I Hydrolase
BHKMAKMB_02617 9.8e-42 yugE S Domain of unknown function (DUF1871)
BHKMAKMB_02618 1.8e-228 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
BHKMAKMB_02619 4.6e-233 T PhoQ Sensor
BHKMAKMB_02620 2e-70 kapB G Kinase associated protein B
BHKMAKMB_02621 1.9e-115 kapD L the KinA pathway to sporulation
BHKMAKMB_02623 3.5e-186 yuxJ EGP Major facilitator Superfamily
BHKMAKMB_02624 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
BHKMAKMB_02625 6.3e-75 yuxK S protein conserved in bacteria
BHKMAKMB_02626 6.3e-78 yufK S Family of unknown function (DUF5366)
BHKMAKMB_02627 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
BHKMAKMB_02628 2.3e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
BHKMAKMB_02629 3.4e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
BHKMAKMB_02630 1.1e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
BHKMAKMB_02631 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
BHKMAKMB_02632 4.5e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
BHKMAKMB_02633 1.3e-233 maeN C COG3493 Na citrate symporter
BHKMAKMB_02634 1.9e-14
BHKMAKMB_02635 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
BHKMAKMB_02636 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
BHKMAKMB_02637 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
BHKMAKMB_02638 3.8e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
BHKMAKMB_02639 4.8e-79 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
BHKMAKMB_02640 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
BHKMAKMB_02641 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
BHKMAKMB_02642 9.2e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
BHKMAKMB_02643 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
BHKMAKMB_02644 0.0 comP 2.7.13.3 T Histidine kinase
BHKMAKMB_02646 2.5e-162 comQ H Polyprenyl synthetase
BHKMAKMB_02648 1.1e-22 yuzC
BHKMAKMB_02649 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
BHKMAKMB_02650 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BHKMAKMB_02651 2.9e-104 pncA Q COG1335 Amidases related to nicotinamidase
BHKMAKMB_02652 1.6e-67 yueI S Protein of unknown function (DUF1694)
BHKMAKMB_02653 7.4e-39 yueH S YueH-like protein
BHKMAKMB_02654 2.1e-32 yueG S Spore germination protein gerPA/gerPF
BHKMAKMB_02655 1.9e-190 yueF S transporter activity
BHKMAKMB_02656 6.1e-72 S Protein of unknown function (DUF2283)
BHKMAKMB_02657 2.9e-24 S Protein of unknown function (DUF2642)
BHKMAKMB_02658 4.8e-96 yueE S phosphohydrolase
BHKMAKMB_02659 4.4e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
BHKMAKMB_02660 6.6e-65 yueC S Family of unknown function (DUF5383)
BHKMAKMB_02661 0.0 esaA S type VII secretion protein EsaA
BHKMAKMB_02662 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
BHKMAKMB_02663 2.3e-211 essB S WXG100 protein secretion system (Wss), protein YukC
BHKMAKMB_02664 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
BHKMAKMB_02665 2.8e-45 esxA S Belongs to the WXG100 family
BHKMAKMB_02666 6.5e-229 yukF QT Transcriptional regulator
BHKMAKMB_02667 1.2e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
BHKMAKMB_02668 1.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
BHKMAKMB_02669 3.8e-36 mbtH S MbtH-like protein
BHKMAKMB_02670 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
BHKMAKMB_02671 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
BHKMAKMB_02672 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
BHKMAKMB_02673 2.3e-226 entC 5.4.4.2 HQ Isochorismate synthase
BHKMAKMB_02674 7.3e-141 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
BHKMAKMB_02675 1.3e-167 besA S Putative esterase
BHKMAKMB_02676 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
BHKMAKMB_02677 1.1e-93 bioY S Biotin biosynthesis protein
BHKMAKMB_02678 3.9e-211 yuiF S antiporter
BHKMAKMB_02679 1.5e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BHKMAKMB_02680 1.2e-77 yuiD S protein conserved in bacteria
BHKMAKMB_02681 5.6e-118 yuiC S protein conserved in bacteria
BHKMAKMB_02682 8.4e-27 yuiB S Putative membrane protein
BHKMAKMB_02683 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
BHKMAKMB_02684 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
BHKMAKMB_02686 4.9e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
BHKMAKMB_02687 9e-118 paiB K Putative FMN-binding domain
BHKMAKMB_02688 4.7e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
BHKMAKMB_02689 3.7e-63 erpA S Belongs to the HesB IscA family
BHKMAKMB_02690 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BHKMAKMB_02691 2.4e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BHKMAKMB_02692 3.2e-39 yuzB S Belongs to the UPF0349 family
BHKMAKMB_02693 1.2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
BHKMAKMB_02694 3.5e-57 yuzD S protein conserved in bacteria
BHKMAKMB_02695 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
BHKMAKMB_02696 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
BHKMAKMB_02697 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
BHKMAKMB_02698 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BHKMAKMB_02699 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
BHKMAKMB_02700 2e-199 yutH S Spore coat protein
BHKMAKMB_02701 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
BHKMAKMB_02702 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
BHKMAKMB_02703 1e-75 yutE S Protein of unknown function DUF86
BHKMAKMB_02704 9.7e-48 yutD S protein conserved in bacteria
BHKMAKMB_02705 4.9e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
BHKMAKMB_02706 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BHKMAKMB_02707 4.5e-196 lytH M Peptidase, M23
BHKMAKMB_02708 8.4e-134 yunB S Sporulation protein YunB (Spo_YunB)
BHKMAKMB_02709 4.8e-48 yunC S Domain of unknown function (DUF1805)
BHKMAKMB_02710 5.8e-266 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
BHKMAKMB_02711 2e-141 yunE S membrane transporter protein
BHKMAKMB_02712 4.3e-171 yunF S Protein of unknown function DUF72
BHKMAKMB_02713 3e-62 yunG
BHKMAKMB_02714 1e-259 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
BHKMAKMB_02715 1.2e-302 pucR QT COG2508 Regulator of polyketide synthase expression
BHKMAKMB_02716 2.1e-236 pbuX F Permease family
BHKMAKMB_02717 1.3e-224 pbuX F xanthine
BHKMAKMB_02718 6.6e-284 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
BHKMAKMB_02719 7.3e-61 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
BHKMAKMB_02720 7.9e-99 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
BHKMAKMB_02721 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
BHKMAKMB_02722 3.4e-152 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
BHKMAKMB_02723 3.6e-111 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
BHKMAKMB_02724 1.7e-190 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BHKMAKMB_02726 1.9e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
BHKMAKMB_02727 1.6e-238 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
BHKMAKMB_02728 2.4e-169 bsn L Ribonuclease
BHKMAKMB_02729 1.2e-205 msmX P Belongs to the ABC transporter superfamily
BHKMAKMB_02730 1.1e-135 yurK K UTRA
BHKMAKMB_02731 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
BHKMAKMB_02732 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
BHKMAKMB_02733 1.4e-156 yurN G Binding-protein-dependent transport system inner membrane component
BHKMAKMB_02734 1.3e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
BHKMAKMB_02735 1.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
BHKMAKMB_02736 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
BHKMAKMB_02737 1.8e-209 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
BHKMAKMB_02739 1e-41
BHKMAKMB_02740 7.6e-67 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
BHKMAKMB_02741 3.5e-271 sufB O FeS cluster assembly
BHKMAKMB_02742 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
BHKMAKMB_02743 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BHKMAKMB_02744 1.4e-245 sufD O assembly protein SufD
BHKMAKMB_02745 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
BHKMAKMB_02746 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BHKMAKMB_02747 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
BHKMAKMB_02748 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
BHKMAKMB_02749 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BHKMAKMB_02750 2.4e-56 yusD S SCP-2 sterol transfer family
BHKMAKMB_02751 5.6e-55 traF CO Thioredoxin
BHKMAKMB_02752 3.3e-74 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
BHKMAKMB_02753 1.1e-39 yusG S Protein of unknown function (DUF2553)
BHKMAKMB_02754 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
BHKMAKMB_02755 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
BHKMAKMB_02756 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
BHKMAKMB_02757 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
BHKMAKMB_02758 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
BHKMAKMB_02759 4.7e-09 S YuzL-like protein
BHKMAKMB_02760 2.2e-165 fadM E Proline dehydrogenase
BHKMAKMB_02761 5.1e-40
BHKMAKMB_02762 3.2e-53 yusN M Coat F domain
BHKMAKMB_02763 5.4e-75 yusO K Iron dependent repressor, N-terminal DNA binding domain
BHKMAKMB_02764 3.8e-293 yusP P Major facilitator superfamily
BHKMAKMB_02765 8.4e-66 yusQ S Tautomerase enzyme
BHKMAKMB_02766 1e-63 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
BHKMAKMB_02767 2.5e-50 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
BHKMAKMB_02768 2.7e-160 yusT K LysR substrate binding domain
BHKMAKMB_02769 3.8e-47 yusU S Protein of unknown function (DUF2573)
BHKMAKMB_02770 1e-153 yusV 3.6.3.34 HP ABC transporter
BHKMAKMB_02771 5.6e-66 S YusW-like protein
BHKMAKMB_02772 6.3e-258 pepF2 E COG1164 Oligoendopeptidase F
BHKMAKMB_02773 3.9e-34 pepF2 E COG1164 Oligoendopeptidase F
BHKMAKMB_02774 4.7e-154 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
BHKMAKMB_02775 1.2e-79 dps P Ferritin-like domain
BHKMAKMB_02776 9.6e-237 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BHKMAKMB_02777 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BHKMAKMB_02778 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
BHKMAKMB_02779 4.3e-158 yuxN K Transcriptional regulator
BHKMAKMB_02780 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
BHKMAKMB_02781 2.3e-24 S Protein of unknown function (DUF3970)
BHKMAKMB_02782 2.2e-247 gerAA EG Spore germination protein
BHKMAKMB_02783 9.1e-198 gerAB E Spore germination protein
BHKMAKMB_02784 4.6e-189 gerAC S Spore germination B3/ GerAC like, C-terminal
BHKMAKMB_02785 1.3e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
BHKMAKMB_02786 5.5e-187 vraS 2.7.13.3 T Histidine kinase
BHKMAKMB_02787 5.6e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
BHKMAKMB_02788 9.3e-129 liaG S Putative adhesin
BHKMAKMB_02789 2.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
BHKMAKMB_02790 5.6e-62 liaI S membrane
BHKMAKMB_02791 4.8e-227 yvqJ EGP Major facilitator Superfamily
BHKMAKMB_02792 6.5e-102 yvqK 2.5.1.17 S Adenosyltransferase
BHKMAKMB_02793 2.8e-249 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
BHKMAKMB_02794 7.7e-186 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BHKMAKMB_02795 1.8e-170 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
BHKMAKMB_02796 6.2e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
BHKMAKMB_02797 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
BHKMAKMB_02798 0.0 T PhoQ Sensor
BHKMAKMB_02799 3.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BHKMAKMB_02800 3.6e-22
BHKMAKMB_02801 1.8e-96 yvrI K RNA polymerase
BHKMAKMB_02802 2.4e-19 S YvrJ protein family
BHKMAKMB_02803 7.3e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
BHKMAKMB_02804 1.3e-64 yvrL S Regulatory protein YrvL
BHKMAKMB_02805 1.8e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
BHKMAKMB_02806 7.1e-124 macB V ABC transporter, ATP-binding protein
BHKMAKMB_02807 4.8e-176 M Efflux transporter rnd family, mfp subunit
BHKMAKMB_02808 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
BHKMAKMB_02809 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BHKMAKMB_02810 9.3e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BHKMAKMB_02811 2.1e-179 fhuD P ABC transporter
BHKMAKMB_02813 2.6e-237 yvsH E Arginine ornithine antiporter
BHKMAKMB_02814 6.5e-16 S Small spore protein J (Spore_SspJ)
BHKMAKMB_02815 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
BHKMAKMB_02816 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
BHKMAKMB_02817 8e-171 yvgK P COG1910 Periplasmic molybdate-binding protein domain
BHKMAKMB_02818 5.8e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
BHKMAKMB_02819 4.7e-120 modB P COG4149 ABC-type molybdate transport system, permease component
BHKMAKMB_02820 9.1e-158 yvgN S reductase
BHKMAKMB_02821 5.4e-86 yvgO
BHKMAKMB_02822 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
BHKMAKMB_02823 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
BHKMAKMB_02824 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BHKMAKMB_02825 0.0 helD 3.6.4.12 L DNA helicase
BHKMAKMB_02826 4.1e-107 yvgT S membrane
BHKMAKMB_02827 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
BHKMAKMB_02828 1.6e-104 bdbD O Thioredoxin
BHKMAKMB_02829 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
BHKMAKMB_02830 0.0 copA 3.6.3.54 P P-type ATPase
BHKMAKMB_02831 1.5e-29 copZ P Copper resistance protein CopZ
BHKMAKMB_02832 2.2e-48 csoR S transcriptional
BHKMAKMB_02833 2.1e-199 yvaA 1.1.1.371 S Oxidoreductase
BHKMAKMB_02834 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BHKMAKMB_02835 0.0 yvaC S Fusaric acid resistance protein-like
BHKMAKMB_02836 5.7e-73 yvaD S Family of unknown function (DUF5360)
BHKMAKMB_02837 2.8e-55 yvaE P Small Multidrug Resistance protein
BHKMAKMB_02838 4.1e-101 K Bacterial regulatory proteins, tetR family
BHKMAKMB_02839 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
BHKMAKMB_02841 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BHKMAKMB_02842 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
BHKMAKMB_02843 5.6e-143 est 3.1.1.1 S Carboxylesterase
BHKMAKMB_02844 2.4e-23 secG U Preprotein translocase subunit SecG
BHKMAKMB_02845 3.7e-153 yvaM S Serine aminopeptidase, S33
BHKMAKMB_02846 7.5e-36 yvzC K Transcriptional
BHKMAKMB_02847 4e-69 K transcriptional
BHKMAKMB_02848 8e-70 yvaO K Cro/C1-type HTH DNA-binding domain
BHKMAKMB_02849 2.2e-54 yodB K transcriptional
BHKMAKMB_02850 4.2e-226 NT chemotaxis protein
BHKMAKMB_02851 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
BHKMAKMB_02852 1.1e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
BHKMAKMB_02853 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
BHKMAKMB_02854 3e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
BHKMAKMB_02855 8.7e-61 yvbF K Belongs to the GbsR family
BHKMAKMB_02856 7.9e-13 S Sporulation delaying protein SdpA
BHKMAKMB_02857 7.6e-172
BHKMAKMB_02858 4.4e-08
BHKMAKMB_02859 3.3e-96 sdpI S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
BHKMAKMB_02860 4.5e-45 sdpR K transcriptional
BHKMAKMB_02861 8.7e-114 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
BHKMAKMB_02862 2.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
BHKMAKMB_02863 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
BHKMAKMB_02864 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
BHKMAKMB_02865 1.4e-98 yvbF K Belongs to the GbsR family
BHKMAKMB_02866 6.4e-103 yvbG U UPF0056 membrane protein
BHKMAKMB_02867 8.6e-113 yvbH S YvbH-like oligomerisation region
BHKMAKMB_02868 4.2e-124 exoY M Membrane
BHKMAKMB_02869 0.0 tcaA S response to antibiotic
BHKMAKMB_02870 7.7e-82 yvbK 3.1.3.25 K acetyltransferase
BHKMAKMB_02871 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
BHKMAKMB_02872 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
BHKMAKMB_02873 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
BHKMAKMB_02874 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
BHKMAKMB_02875 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
BHKMAKMB_02876 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
BHKMAKMB_02877 1.6e-252 araE EGP Major facilitator Superfamily
BHKMAKMB_02878 5.5e-203 araR K transcriptional
BHKMAKMB_02879 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BHKMAKMB_02880 3.9e-159 yvbU K Transcriptional regulator
BHKMAKMB_02881 8.5e-157 yvbV EG EamA-like transporter family
BHKMAKMB_02882 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
BHKMAKMB_02883 4.3e-197 yvbX S Glycosyl hydrolase
BHKMAKMB_02884 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
BHKMAKMB_02885 1.2e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
BHKMAKMB_02886 1.5e-137 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
BHKMAKMB_02887 2.6e-106 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
BHKMAKMB_02888 8.9e-201 desK 2.7.13.3 T Histidine kinase
BHKMAKMB_02889 6.2e-134 yvfS V COG0842 ABC-type multidrug transport system, permease component
BHKMAKMB_02890 3e-162 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
BHKMAKMB_02891 2.6e-157 rsbQ S Alpha/beta hydrolase family
BHKMAKMB_02892 1.4e-199 rsbU 3.1.3.3 T response regulator
BHKMAKMB_02893 2.6e-252 galA 3.2.1.89 G arabinogalactan
BHKMAKMB_02894 0.0 lacA 3.2.1.23 G beta-galactosidase
BHKMAKMB_02895 3.2e-150 ganQ P transport
BHKMAKMB_02896 1.3e-232 malC P COG1175 ABC-type sugar transport systems, permease components
BHKMAKMB_02897 2.9e-232 cycB G COG2182 Maltose-binding periplasmic proteins domains
BHKMAKMB_02898 1.8e-184 lacR K Transcriptional regulator
BHKMAKMB_02899 6.6e-111 yvfI K COG2186 Transcriptional regulators
BHKMAKMB_02900 1.4e-309 yvfH C L-lactate permease
BHKMAKMB_02901 6.5e-243 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
BHKMAKMB_02902 1e-31 yvfG S YvfG protein
BHKMAKMB_02903 5.8e-188 yvfF GM Exopolysaccharide biosynthesis protein
BHKMAKMB_02904 1.2e-224 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
BHKMAKMB_02905 2.2e-58 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
BHKMAKMB_02906 2.6e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
BHKMAKMB_02907 8.9e-260 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
BHKMAKMB_02908 1.9e-197 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
BHKMAKMB_02909 3.6e-207 epsI GM pyruvyl transferase
BHKMAKMB_02910 3.6e-196 epsH GT2 S Glycosyltransferase like family 2
BHKMAKMB_02911 4.8e-207 epsG S EpsG family
BHKMAKMB_02912 5.3e-220 epsF GT4 M Glycosyl transferases group 1
BHKMAKMB_02913 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
BHKMAKMB_02914 2e-224 epsD GT4 M Glycosyl transferase 4-like
BHKMAKMB_02915 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
BHKMAKMB_02916 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
BHKMAKMB_02917 4e-122 ywqC M biosynthesis protein
BHKMAKMB_02918 5.7e-77 slr K transcriptional
BHKMAKMB_02919 4.8e-287 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
BHKMAKMB_02921 4.6e-93 padC Q Phenolic acid decarboxylase
BHKMAKMB_02922 1.3e-48 MA20_18690 S Protein of unknown function (DUF3237)
BHKMAKMB_02923 3.1e-127 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
BHKMAKMB_02924 9.6e-266 pbpE V Beta-lactamase
BHKMAKMB_02925 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
BHKMAKMB_02926 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
BHKMAKMB_02927 1.8e-295 yveA E amino acid
BHKMAKMB_02928 2.6e-106 yvdT K Transcriptional regulator
BHKMAKMB_02929 6.7e-51 ykkC P Small Multidrug Resistance protein
BHKMAKMB_02930 4.1e-50 sugE P Small Multidrug Resistance protein
BHKMAKMB_02931 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
BHKMAKMB_02932 8.4e-270 ygaK C COG0277 FAD FMN-containing dehydrogenases
BHKMAKMB_02933 1.5e-183 S Patatin-like phospholipase
BHKMAKMB_02935 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
BHKMAKMB_02936 1.3e-122 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
BHKMAKMB_02937 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
BHKMAKMB_02938 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
BHKMAKMB_02939 1.2e-158 malA S Protein of unknown function (DUF1189)
BHKMAKMB_02940 7.8e-149 malD P transport
BHKMAKMB_02941 5.3e-245 malC P COG1175 ABC-type sugar transport systems, permease components
BHKMAKMB_02942 1.3e-235 mdxE G COG2182 Maltose-binding periplasmic proteins domains
BHKMAKMB_02943 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
BHKMAKMB_02944 3.6e-174 yvdE K Transcriptional regulator
BHKMAKMB_02945 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
BHKMAKMB_02946 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
BHKMAKMB_02947 2.1e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
BHKMAKMB_02948 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
BHKMAKMB_02949 1.3e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BHKMAKMB_02950 0.0 yxdM V ABC transporter (permease)
BHKMAKMB_02951 5.6e-141 yvcR V ABC transporter, ATP-binding protein
BHKMAKMB_02952 2.3e-198 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
BHKMAKMB_02953 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BHKMAKMB_02954 1.8e-33
BHKMAKMB_02955 8.6e-147 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
BHKMAKMB_02956 1.6e-36 crh G Phosphocarrier protein Chr
BHKMAKMB_02957 1.4e-170 whiA K May be required for sporulation
BHKMAKMB_02958 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
BHKMAKMB_02959 5.7e-166 rapZ S Displays ATPase and GTPase activities
BHKMAKMB_02960 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
BHKMAKMB_02961 1.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
BHKMAKMB_02962 1.4e-102 usp CBM50 M protein conserved in bacteria
BHKMAKMB_02963 2.4e-278 S COG0457 FOG TPR repeat
BHKMAKMB_02964 0.0 msbA2 3.6.3.44 V ABC transporter
BHKMAKMB_02966 0.0
BHKMAKMB_02967 4.6e-121
BHKMAKMB_02968 8e-114 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
BHKMAKMB_02969 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
BHKMAKMB_02970 3.1e-133 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BHKMAKMB_02971 1.7e-116 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BHKMAKMB_02972 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
BHKMAKMB_02973 6.6e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BHKMAKMB_02974 1.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
BHKMAKMB_02975 4.8e-221 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BHKMAKMB_02976 4.5e-140 yvpB NU protein conserved in bacteria
BHKMAKMB_02977 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
BHKMAKMB_02978 3e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
BHKMAKMB_02979 1.3e-119 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
BHKMAKMB_02980 1.5e-164 yvoD P COG0370 Fe2 transport system protein B
BHKMAKMB_02981 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BHKMAKMB_02982 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BHKMAKMB_02983 6.8e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
BHKMAKMB_02984 8.9e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
BHKMAKMB_02985 3.6e-134 yvoA K transcriptional
BHKMAKMB_02986 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
BHKMAKMB_02987 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
BHKMAKMB_02988 8.2e-232 cypX 1.14.15.13 C Cytochrome P450
BHKMAKMB_02989 1.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
BHKMAKMB_02990 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
BHKMAKMB_02991 2.7e-203 yvmA EGP Major facilitator Superfamily
BHKMAKMB_02992 1.2e-50 yvlD S Membrane
BHKMAKMB_02993 2.6e-26 pspB KT PspC domain
BHKMAKMB_02994 3.4e-168 yvlB S Putative adhesin
BHKMAKMB_02995 8e-49 yvlA
BHKMAKMB_02996 6.7e-34 yvkN
BHKMAKMB_02997 2.9e-79 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BHKMAKMB_02998 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
BHKMAKMB_02999 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
BHKMAKMB_03000 1.2e-30 csbA S protein conserved in bacteria
BHKMAKMB_03001 0.0 yvkC 2.7.9.2 GT Phosphotransferase
BHKMAKMB_03002 7e-101 yvkB K Transcriptional regulator
BHKMAKMB_03003 7.9e-228 yvkA EGP Major facilitator Superfamily
BHKMAKMB_03004 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BHKMAKMB_03005 1e-54 swrA S Swarming motility protein
BHKMAKMB_03006 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
BHKMAKMB_03007 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
BHKMAKMB_03008 1.6e-123 ftsE D cell division ATP-binding protein FtsE
BHKMAKMB_03009 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
BHKMAKMB_03010 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
BHKMAKMB_03011 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BHKMAKMB_03012 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
BHKMAKMB_03013 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BHKMAKMB_03014 2.8e-66
BHKMAKMB_03015 1.9e-08 fliT S bacterial-type flagellum organization
BHKMAKMB_03016 2.9e-69 fliS N flagellar protein FliS
BHKMAKMB_03017 1.3e-266 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BHKMAKMB_03018 6.1e-57 flaG N flagellar protein FlaG
BHKMAKMB_03019 1.9e-156 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BHKMAKMB_03020 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BHKMAKMB_03021 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BHKMAKMB_03022 2.6e-50 yviE
BHKMAKMB_03023 1.1e-156 flgL N Belongs to the bacterial flagellin family
BHKMAKMB_03024 1.2e-264 flgK N flagellar hook-associated protein
BHKMAKMB_03025 2.4e-78 flgN NOU FlgN protein
BHKMAKMB_03026 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
BHKMAKMB_03027 7e-74 yvyF S flagellar protein
BHKMAKMB_03028 2.7e-129 comFC S Phosphoribosyl transferase domain
BHKMAKMB_03029 5.7e-46 comFB S Late competence development protein ComFB
BHKMAKMB_03030 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BHKMAKMB_03031 7.3e-155 degV S protein conserved in bacteria
BHKMAKMB_03032 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
BHKMAKMB_03033 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
BHKMAKMB_03034 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
BHKMAKMB_03035 6e-163 yvhJ K Transcriptional regulator
BHKMAKMB_03036 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
BHKMAKMB_03037 4.4e-238 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
BHKMAKMB_03038 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
BHKMAKMB_03039 6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
BHKMAKMB_03040 1.7e-263 tuaE M Teichuronic acid biosynthesis protein
BHKMAKMB_03041 2.4e-259 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BHKMAKMB_03042 7.4e-222 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
BHKMAKMB_03043 3.3e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
BHKMAKMB_03044 2.7e-78 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
BHKMAKMB_03045 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
BHKMAKMB_03046 0.0 lytB 3.5.1.28 D Stage II sporulation protein
BHKMAKMB_03047 6e-38
BHKMAKMB_03048 6.1e-163 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
BHKMAKMB_03049 8.2e-218 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
BHKMAKMB_03050 9e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
BHKMAKMB_03051 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
BHKMAKMB_03052 8.1e-257 ggaA M Glycosyltransferase like family 2
BHKMAKMB_03054 1.6e-100 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
BHKMAKMB_03055 1.8e-279 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
BHKMAKMB_03056 1.1e-150 tagG GM Transport permease protein
BHKMAKMB_03057 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BHKMAKMB_03058 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
BHKMAKMB_03059 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
BHKMAKMB_03060 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
BHKMAKMB_03061 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BHKMAKMB_03062 1.2e-260
BHKMAKMB_03063 7.2e-217 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
BHKMAKMB_03064 7.1e-191 pmi 5.3.1.8 G mannose-6-phosphate isomerase
BHKMAKMB_03065 3.5e-266 gerBA EG Spore germination protein
BHKMAKMB_03066 7.5e-200 gerBB E Spore germination protein
BHKMAKMB_03067 7.6e-216 gerAC S Spore germination protein
BHKMAKMB_03068 1.9e-248 ywtG EGP Major facilitator Superfamily
BHKMAKMB_03069 8.4e-171 ywtF K Transcriptional regulator
BHKMAKMB_03070 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
BHKMAKMB_03071 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
BHKMAKMB_03072 3.6e-21 ywtC
BHKMAKMB_03073 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
BHKMAKMB_03074 8.6e-70 pgsC S biosynthesis protein
BHKMAKMB_03075 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
BHKMAKMB_03076 1.5e-180 rbsR K transcriptional
BHKMAKMB_03077 2.9e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BHKMAKMB_03078 2.8e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
BHKMAKMB_03079 2.3e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
BHKMAKMB_03080 1.4e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
BHKMAKMB_03081 4.4e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
BHKMAKMB_03082 4.6e-94 batE T Sh3 type 3 domain protein
BHKMAKMB_03083 3.6e-48 ywsA S Protein of unknown function (DUF3892)
BHKMAKMB_03084 1.5e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
BHKMAKMB_03085 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
BHKMAKMB_03086 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
BHKMAKMB_03087 1.1e-169 alsR K LysR substrate binding domain
BHKMAKMB_03088 1.9e-220 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BHKMAKMB_03089 7.5e-126 ywrJ
BHKMAKMB_03090 7.6e-131 cotB
BHKMAKMB_03091 1.2e-210 cotH M Spore Coat
BHKMAKMB_03092 3.7e-12
BHKMAKMB_03093 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BHKMAKMB_03094 2.9e-54 S Domain of unknown function (DUF4181)
BHKMAKMB_03095 9.6e-310 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
BHKMAKMB_03096 2.1e-82 ywrC K Transcriptional regulator
BHKMAKMB_03097 2.4e-104 ywrB P Chromate transporter
BHKMAKMB_03098 6.9e-90 ywrA P COG2059 Chromate transport protein ChrA
BHKMAKMB_03100 2.7e-102 ywqN S NAD(P)H-dependent
BHKMAKMB_03101 2.9e-162 K Transcriptional regulator
BHKMAKMB_03102 4.5e-137 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
BHKMAKMB_03103 1.7e-52 S MORN repeat variant
BHKMAKMB_03104 0.0 ywqJ L nucleic acid phosphodiester bond hydrolysis
BHKMAKMB_03105 1.3e-38 ywqI S Family of unknown function (DUF5344)
BHKMAKMB_03106 3.3e-15 S Domain of unknown function (DUF5082)
BHKMAKMB_03107 3.4e-154 ywqG S Domain of unknown function (DUF1963)
BHKMAKMB_03108 3e-248 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BHKMAKMB_03109 1.4e-141 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
BHKMAKMB_03110 1.1e-119 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
BHKMAKMB_03111 2e-116 ywqC M biosynthesis protein
BHKMAKMB_03112 1.2e-17
BHKMAKMB_03113 3.8e-309 ywqB S SWIM zinc finger
BHKMAKMB_03114 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
BHKMAKMB_03115 3.6e-157 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
BHKMAKMB_03116 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
BHKMAKMB_03117 9.8e-58 ssbB L Single-stranded DNA-binding protein
BHKMAKMB_03118 1.3e-66 ywpG
BHKMAKMB_03119 1.1e-66 ywpF S YwpF-like protein
BHKMAKMB_03120 8e-51 srtA 3.4.22.70 M Sortase family
BHKMAKMB_03121 1.9e-153 ywpD T Histidine kinase
BHKMAKMB_03122 1.5e-54 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
BHKMAKMB_03123 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
BHKMAKMB_03124 2.1e-199 S aspartate phosphatase
BHKMAKMB_03125 1.5e-141 flhP N flagellar basal body
BHKMAKMB_03126 6.9e-126 flhO N flagellar basal body
BHKMAKMB_03127 3.5e-180 mbl D Rod shape-determining protein
BHKMAKMB_03128 3e-44 spoIIID K Stage III sporulation protein D
BHKMAKMB_03129 2.1e-70 ywoH K COG1846 Transcriptional regulators
BHKMAKMB_03130 2.7e-211 ywoG EGP Major facilitator Superfamily
BHKMAKMB_03131 1.2e-231 ywoF P Right handed beta helix region
BHKMAKMB_03132 3e-281 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
BHKMAKMB_03133 4.4e-242 ywoD EGP Major facilitator superfamily
BHKMAKMB_03134 4e-104 phzA Q Isochorismatase family
BHKMAKMB_03135 1.2e-77
BHKMAKMB_03136 2.5e-225 amt P Ammonium transporter
BHKMAKMB_03137 1.6e-58 nrgB K Belongs to the P(II) protein family
BHKMAKMB_03138 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
BHKMAKMB_03139 3.5e-73 ywnJ S VanZ like family
BHKMAKMB_03140 5.5e-126 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
BHKMAKMB_03141 6.4e-90 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
BHKMAKMB_03142 2.7e-14 ywnC S Family of unknown function (DUF5362)
BHKMAKMB_03143 2.2e-70 ywnF S Family of unknown function (DUF5392)
BHKMAKMB_03144 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BHKMAKMB_03145 4.1e-144 mta K transcriptional
BHKMAKMB_03146 2.6e-59 ywnC S Family of unknown function (DUF5362)
BHKMAKMB_03147 1.6e-114 ywnB S NAD(P)H-binding
BHKMAKMB_03148 1.7e-64 ywnA K Transcriptional regulator
BHKMAKMB_03149 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
BHKMAKMB_03150 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
BHKMAKMB_03151 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
BHKMAKMB_03153 3.8e-11 csbD K CsbD-like
BHKMAKMB_03154 3e-84 ywmF S Peptidase M50
BHKMAKMB_03155 1.3e-103 S response regulator aspartate phosphatase
BHKMAKMB_03156 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BHKMAKMB_03157 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BHKMAKMB_03159 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
BHKMAKMB_03160 5.1e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
BHKMAKMB_03161 5.8e-178 spoIID D Stage II sporulation protein D
BHKMAKMB_03162 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BHKMAKMB_03163 1.6e-134 ywmB S TATA-box binding
BHKMAKMB_03164 1.3e-32 ywzB S membrane
BHKMAKMB_03165 4.3e-88 ywmA
BHKMAKMB_03166 5.9e-54 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
BHKMAKMB_03167 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BHKMAKMB_03168 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BHKMAKMB_03169 6.9e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BHKMAKMB_03170 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BHKMAKMB_03171 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BHKMAKMB_03172 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BHKMAKMB_03173 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
BHKMAKMB_03174 2.5e-62 atpI S ATP synthase
BHKMAKMB_03175 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BHKMAKMB_03176 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BHKMAKMB_03177 7.2e-95 ywlG S Belongs to the UPF0340 family
BHKMAKMB_03178 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
BHKMAKMB_03179 1.7e-78 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BHKMAKMB_03180 1.7e-91 mntP P Probably functions as a manganese efflux pump
BHKMAKMB_03181 1.2e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
BHKMAKMB_03182 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
BHKMAKMB_03183 6.1e-112 spoIIR S stage II sporulation protein R
BHKMAKMB_03184 3.4e-56 ywlA S Uncharacterised protein family (UPF0715)
BHKMAKMB_03186 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
BHKMAKMB_03187 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BHKMAKMB_03188 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
BHKMAKMB_03189 1.7e-91 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
BHKMAKMB_03190 8.6e-160 ywkB S Membrane transport protein
BHKMAKMB_03191 0.0 sfcA 1.1.1.38 C malic enzyme
BHKMAKMB_03192 2.4e-104 tdk 2.7.1.21 F thymidine kinase
BHKMAKMB_03193 1.1e-32 rpmE J Binds the 23S rRNA
BHKMAKMB_03194 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BHKMAKMB_03195 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
BHKMAKMB_03196 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BHKMAKMB_03197 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BHKMAKMB_03198 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
BHKMAKMB_03199 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
BHKMAKMB_03200 2.4e-92 ywjG S Domain of unknown function (DUF2529)
BHKMAKMB_03201 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
BHKMAKMB_03202 1.5e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
BHKMAKMB_03203 2.6e-211 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
BHKMAKMB_03204 0.0 fadF C COG0247 Fe-S oxidoreductase
BHKMAKMB_03205 2.3e-223 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
BHKMAKMB_03206 6.6e-184 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
BHKMAKMB_03207 2.7e-42 ywjC
BHKMAKMB_03208 4.8e-96 ywjB H RibD C-terminal domain
BHKMAKMB_03209 0.0 ywjA V ABC transporter
BHKMAKMB_03210 6.4e-287 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BHKMAKMB_03211 1.8e-124 narI 1.7.5.1 C nitrate reductase, gamma
BHKMAKMB_03212 2.4e-98 narJ 1.7.5.1 C nitrate reductase
BHKMAKMB_03213 1e-297 narH 1.7.5.1 C Nitrate reductase, beta
BHKMAKMB_03214 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BHKMAKMB_03215 7e-86 arfM T cyclic nucleotide binding
BHKMAKMB_03216 4.3e-140 ywiC S YwiC-like protein
BHKMAKMB_03217 5.3e-130 fnr K helix_turn_helix, cAMP Regulatory protein
BHKMAKMB_03218 9.8e-214 narK P COG2223 Nitrate nitrite transporter
BHKMAKMB_03219 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
BHKMAKMB_03220 4.7e-73 ywiB S protein conserved in bacteria
BHKMAKMB_03221 1e-07 S Bacteriocin subtilosin A
BHKMAKMB_03222 2.6e-271 C Fe-S oxidoreductases
BHKMAKMB_03224 3.3e-132 cbiO V ABC transporter
BHKMAKMB_03225 3.1e-237 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
BHKMAKMB_03226 2.7e-219 2.7.1.26, 2.7.7.2 L Peptidase, M16
BHKMAKMB_03227 1.2e-249 L Peptidase, M16
BHKMAKMB_03229 2.9e-249 ywhL CO amine dehydrogenase activity
BHKMAKMB_03230 2.5e-205 ywhK CO amine dehydrogenase activity
BHKMAKMB_03231 2.3e-79 S aspartate phosphatase
BHKMAKMB_03233 1e-84 ywhH S Aminoacyl-tRNA editing domain
BHKMAKMB_03234 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
BHKMAKMB_03235 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BHKMAKMB_03236 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
BHKMAKMB_03237 5.2e-95 ywhD S YwhD family
BHKMAKMB_03238 5.1e-119 ywhC S Peptidase family M50
BHKMAKMB_03239 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
BHKMAKMB_03240 3.3e-71 ywhA K Transcriptional regulator
BHKMAKMB_03241 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BHKMAKMB_03243 2.6e-242 mmr U Major Facilitator Superfamily
BHKMAKMB_03244 2.8e-79 yffB K Transcriptional regulator
BHKMAKMB_03245 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
BHKMAKMB_03246 1.8e-256 ywfO S COG1078 HD superfamily phosphohydrolases
BHKMAKMB_03247 3.1e-36 ywzC S Belongs to the UPF0741 family
BHKMAKMB_03248 1.6e-111 rsfA_1
BHKMAKMB_03249 5.2e-159 ywfM EG EamA-like transporter family
BHKMAKMB_03250 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
BHKMAKMB_03251 9.2e-164 cysL K Transcriptional regulator
BHKMAKMB_03252 6.6e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
BHKMAKMB_03253 1.1e-146 ywfI C May function as heme-dependent peroxidase
BHKMAKMB_03254 4e-139 IQ Enoyl-(Acyl carrier protein) reductase
BHKMAKMB_03255 2.7e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
BHKMAKMB_03256 2.9e-210 bacE EGP Major facilitator Superfamily
BHKMAKMB_03257 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
BHKMAKMB_03258 1.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
BHKMAKMB_03259 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
BHKMAKMB_03260 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
BHKMAKMB_03261 4.6e-206 ywfA EGP Major facilitator Superfamily
BHKMAKMB_03262 4e-262 lysP E amino acid
BHKMAKMB_03263 0.0 rocB E arginine degradation protein
BHKMAKMB_03264 1.4e-297 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
BHKMAKMB_03265 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
BHKMAKMB_03266 1.8e-78
BHKMAKMB_03267 3.5e-87 spsL 5.1.3.13 M Spore Coat
BHKMAKMB_03268 5.3e-161 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
BHKMAKMB_03269 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
BHKMAKMB_03270 1.9e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BHKMAKMB_03271 1.7e-190 spsG M Spore Coat
BHKMAKMB_03272 9.7e-132 spsF M Spore Coat
BHKMAKMB_03273 3.2e-214 spsE 2.5.1.56 M acid synthase
BHKMAKMB_03274 4e-164 spsD 2.3.1.210 K Spore Coat
BHKMAKMB_03275 1.6e-224 spsC E Belongs to the DegT DnrJ EryC1 family
BHKMAKMB_03276 1.5e-269 spsB M Capsule polysaccharide biosynthesis protein
BHKMAKMB_03277 2.8e-145 spsA M Spore Coat
BHKMAKMB_03278 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
BHKMAKMB_03279 4.3e-59 ywdK S small membrane protein
BHKMAKMB_03280 1.3e-238 ywdJ F Xanthine uracil
BHKMAKMB_03281 7.7e-49 ywdI S Family of unknown function (DUF5327)
BHKMAKMB_03282 1.3e-262 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
BHKMAKMB_03283 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BHKMAKMB_03284 1.1e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
BHKMAKMB_03286 1.4e-113 ywdD
BHKMAKMB_03287 1.3e-57 pex K Transcriptional regulator PadR-like family
BHKMAKMB_03288 9.3e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
BHKMAKMB_03289 2e-28 ywdA
BHKMAKMB_03290 2.8e-295 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
BHKMAKMB_03291 6.9e-251 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
BHKMAKMB_03292 1.9e-133 focA P Formate/nitrite transporter
BHKMAKMB_03293 1e-148 sacT K transcriptional antiterminator
BHKMAKMB_03295 0.0 vpr O Belongs to the peptidase S8 family
BHKMAKMB_03296 5.1e-187 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BHKMAKMB_03297 7.2e-138 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
BHKMAKMB_03298 2.9e-202 rodA D Belongs to the SEDS family
BHKMAKMB_03299 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
BHKMAKMB_03300 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
BHKMAKMB_03301 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
BHKMAKMB_03302 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BHKMAKMB_03303 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
BHKMAKMB_03304 1e-35 ywzA S membrane
BHKMAKMB_03305 3.7e-306 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
BHKMAKMB_03306 6.2e-229 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BHKMAKMB_03307 9.5e-60 gtcA S GtrA-like protein
BHKMAKMB_03308 2.2e-122 ywcC K transcriptional regulator
BHKMAKMB_03310 9.8e-49 ywcB S Protein of unknown function, DUF485
BHKMAKMB_03311 8.3e-180 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BHKMAKMB_03312 2e-71 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BHKMAKMB_03313 1.9e-112 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
BHKMAKMB_03314 2.6e-225 ywbN P Dyp-type peroxidase family protein
BHKMAKMB_03315 2e-187 ycdO P periplasmic lipoprotein involved in iron transport
BHKMAKMB_03316 8.2e-255 P COG0672 High-affinity Fe2 Pb2 permease
BHKMAKMB_03317 4.1e-116 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
BHKMAKMB_03318 2.8e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BHKMAKMB_03319 4.3e-153 ywbI K Transcriptional regulator
BHKMAKMB_03320 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
BHKMAKMB_03321 2.3e-111 ywbG M effector of murein hydrolase
BHKMAKMB_03322 1.9e-209 ywbF EGP Major facilitator Superfamily
BHKMAKMB_03323 1.2e-28 ywbE S Uncharacterized conserved protein (DUF2196)
BHKMAKMB_03324 8.9e-223 ywbD 2.1.1.191 J Methyltransferase
BHKMAKMB_03325 4.4e-67 ywbC 4.4.1.5 E glyoxalase
BHKMAKMB_03326 1.8e-127 ywbB S Protein of unknown function (DUF2711)
BHKMAKMB_03327 5.8e-247 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
BHKMAKMB_03328 1.6e-277 epr 3.4.21.62 O Belongs to the peptidase S8 family
BHKMAKMB_03329 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
BHKMAKMB_03330 4e-153 sacY K transcriptional antiterminator
BHKMAKMB_03331 7e-169 gspA M General stress
BHKMAKMB_03332 1.7e-128 ywaF S Integral membrane protein
BHKMAKMB_03333 8.1e-88 ywaE K Transcriptional regulator
BHKMAKMB_03334 4.4e-233 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BHKMAKMB_03335 1.4e-251 ywaD 3.4.11.10, 3.4.11.6 S PA domain
BHKMAKMB_03336 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
BHKMAKMB_03337 5.4e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
BHKMAKMB_03338 5e-14 S D-Ala-teichoic acid biosynthesis protein
BHKMAKMB_03339 7.9e-293 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
BHKMAKMB_03340 1.2e-232 dltB M membrane protein involved in D-alanine export
BHKMAKMB_03341 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
BHKMAKMB_03342 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BHKMAKMB_03343 6.6e-139 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
BHKMAKMB_03344 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
BHKMAKMB_03345 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
BHKMAKMB_03346 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
BHKMAKMB_03347 7.4e-250 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
BHKMAKMB_03348 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
BHKMAKMB_03349 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
BHKMAKMB_03350 1.1e-19 yxzF
BHKMAKMB_03351 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
BHKMAKMB_03352 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
BHKMAKMB_03353 2.1e-216 yxlH EGP Major facilitator Superfamily
BHKMAKMB_03354 1.8e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
BHKMAKMB_03355 5.1e-167 yxlF V ABC transporter, ATP-binding protein
BHKMAKMB_03356 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
BHKMAKMB_03357 1.2e-31
BHKMAKMB_03358 3.9e-48 yxlC S Family of unknown function (DUF5345)
BHKMAKMB_03359 4.7e-91 sigY K Belongs to the sigma-70 factor family. ECF subfamily
BHKMAKMB_03360 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
BHKMAKMB_03361 8e-162 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BHKMAKMB_03362 0.0 cydD V ATP-binding protein
BHKMAKMB_03363 0.0 cydD V ATP-binding
BHKMAKMB_03364 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
BHKMAKMB_03365 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
BHKMAKMB_03366 1.5e-229 cimH C COG3493 Na citrate symporter
BHKMAKMB_03367 0.0 3.4.24.84 O Peptidase family M48
BHKMAKMB_03369 3e-156 yxkH G Polysaccharide deacetylase
BHKMAKMB_03370 5.9e-205 msmK P Belongs to the ABC transporter superfamily
BHKMAKMB_03371 4.8e-165 lrp QT PucR C-terminal helix-turn-helix domain
BHKMAKMB_03372 2.5e-275 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
BHKMAKMB_03373 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
BHKMAKMB_03374 4.1e-73 yxkC S Domain of unknown function (DUF4352)
BHKMAKMB_03375 4.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
BHKMAKMB_03376 1.3e-95 yxkA S Phosphatidylethanolamine-binding protein
BHKMAKMB_03377 1.9e-166 yxjO K LysR substrate binding domain
BHKMAKMB_03378 2.4e-78 S Protein of unknown function (DUF1453)
BHKMAKMB_03379 1.5e-193 yxjM T Signal transduction histidine kinase
BHKMAKMB_03380 8.9e-116 K helix_turn_helix, Lux Regulon
BHKMAKMB_03381 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
BHKMAKMB_03384 1e-87 yxjI S LURP-one-related
BHKMAKMB_03385 5.5e-222 yxjG 2.1.1.14 E Methionine synthase
BHKMAKMB_03386 1e-220 yxjG 2.1.1.14 E Methionine synthase
BHKMAKMB_03387 1.3e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
BHKMAKMB_03388 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
BHKMAKMB_03389 1.4e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BHKMAKMB_03390 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
BHKMAKMB_03391 2.2e-145 rlmA 2.1.1.187 Q Methyltransferase domain
BHKMAKMB_03392 1.9e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BHKMAKMB_03393 1.2e-22 T Domain of unknown function (DUF4163)
BHKMAKMB_03394 2.7e-48 yxiS
BHKMAKMB_03395 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
BHKMAKMB_03396 6.6e-224 citH C Citrate transporter
BHKMAKMB_03397 5e-144 exoK GH16 M licheninase activity
BHKMAKMB_03398 8.3e-151 licT K transcriptional antiterminator
BHKMAKMB_03399 6.6e-114
BHKMAKMB_03400 3e-232 yxiO S COG2270 Permeases of the major facilitator superfamily
BHKMAKMB_03401 1e-265 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
BHKMAKMB_03402 7.5e-219 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
BHKMAKMB_03405 1.6e-48 yxiJ S YxiJ-like protein
BHKMAKMB_03406 1.2e-96 yxiI S Protein of unknown function (DUF2716)
BHKMAKMB_03407 3.8e-81
BHKMAKMB_03408 4.9e-46
BHKMAKMB_03409 3.7e-75 yxiG
BHKMAKMB_03410 6.4e-63
BHKMAKMB_03411 1.7e-84
BHKMAKMB_03412 1.5e-71 yxxG
BHKMAKMB_03413 0.0 wapA M COG3209 Rhs family protein
BHKMAKMB_03414 2.9e-168 yxxF EG EamA-like transporter family
BHKMAKMB_03415 1.1e-72 yxiE T Belongs to the universal stress protein A family
BHKMAKMB_03416 6.6e-281 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
BHKMAKMB_03417 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
BHKMAKMB_03418 3.6e-51
BHKMAKMB_03419 2.2e-78 S SMI1 / KNR4 family
BHKMAKMB_03420 0.0 S nuclease activity
BHKMAKMB_03421 3.6e-39 yxiC S Family of unknown function (DUF5344)
BHKMAKMB_03422 2.1e-21 S Domain of unknown function (DUF5082)
BHKMAKMB_03423 6.3e-284 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
BHKMAKMB_03424 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
BHKMAKMB_03425 2.3e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
BHKMAKMB_03426 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BHKMAKMB_03427 1.2e-238 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
BHKMAKMB_03428 8e-182 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
BHKMAKMB_03429 6.1e-252 lysP E amino acid
BHKMAKMB_03430 4.2e-234 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
BHKMAKMB_03431 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BHKMAKMB_03432 7e-116 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BHKMAKMB_03433 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
BHKMAKMB_03434 3e-153 yxxB S Domain of Unknown Function (DUF1206)
BHKMAKMB_03435 6.8e-201 eutH E Ethanolamine utilisation protein, EutH
BHKMAKMB_03436 2e-255 yxeQ S MmgE/PrpD family
BHKMAKMB_03437 3.8e-215 yxeP 3.5.1.47 E hydrolase activity
BHKMAKMB_03438 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
BHKMAKMB_03439 5.4e-108 yxeN P COG0765 ABC-type amino acid transport system, permease component
BHKMAKMB_03440 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
BHKMAKMB_03441 7.3e-94 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
BHKMAKMB_03442 2.2e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BHKMAKMB_03444 8.8e-192 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
BHKMAKMB_03445 6.2e-151 yidA S hydrolases of the HAD superfamily
BHKMAKMB_03448 1.3e-20 yxeE
BHKMAKMB_03449 1.9e-16 yxeD
BHKMAKMB_03450 8.5e-69
BHKMAKMB_03451 6e-177 fhuD P ABC transporter
BHKMAKMB_03452 1.5e-58 yxeA S Protein of unknown function (DUF1093)
BHKMAKMB_03453 0.0 yxdM V ABC transporter (permease)
BHKMAKMB_03454 9.4e-141 yxdL V ABC transporter, ATP-binding protein
BHKMAKMB_03455 1.3e-182 T PhoQ Sensor
BHKMAKMB_03456 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BHKMAKMB_03457 5.4e-161 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
BHKMAKMB_03458 1.9e-139 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
BHKMAKMB_03459 2.3e-167 iolH G Xylose isomerase-like TIM barrel
BHKMAKMB_03460 2.8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
BHKMAKMB_03461 1.3e-235 iolF EGP Major facilitator Superfamily
BHKMAKMB_03462 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
BHKMAKMB_03463 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
BHKMAKMB_03464 2.9e-179 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
BHKMAKMB_03465 1.1e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
BHKMAKMB_03466 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
BHKMAKMB_03467 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
BHKMAKMB_03468 3.7e-176 iolS C Aldo keto reductase
BHKMAKMB_03470 8.3e-48 yxcD S Protein of unknown function (DUF2653)
BHKMAKMB_03471 2.3e-246 csbC EGP Major facilitator Superfamily
BHKMAKMB_03472 0.0 htpG O Molecular chaperone. Has ATPase activity
BHKMAKMB_03474 5.7e-152 IQ Enoyl-(Acyl carrier protein) reductase
BHKMAKMB_03475 2.2e-215 yxbF K Bacterial regulatory proteins, tetR family
BHKMAKMB_03476 1.4e-248 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
BHKMAKMB_03477 1.6e-85 yxbD 3.2.2.20 K Acetyltransferase (GNAT) domain
BHKMAKMB_03478 2.2e-187 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
BHKMAKMB_03479 3.3e-127 yxbB Q Met-10+ like-protein
BHKMAKMB_03480 4.9e-44 S Coenzyme PQQ synthesis protein D (PqqD)
BHKMAKMB_03481 1.1e-86 yxnB
BHKMAKMB_03482 0.0 asnB 6.3.5.4 E Asparagine synthase
BHKMAKMB_03483 7.6e-214 yxaM U MFS_1 like family
BHKMAKMB_03484 6.8e-93 S PQQ-like domain
BHKMAKMB_03485 3.5e-65 S Family of unknown function (DUF5391)
BHKMAKMB_03486 1.1e-75 yxaI S membrane protein domain
BHKMAKMB_03487 1.4e-228 P Protein of unknown function (DUF418)
BHKMAKMB_03488 1.5e-199 yxaG 1.13.11.24 S AraC-like ligand binding domain
BHKMAKMB_03489 7.1e-101 yxaF K Transcriptional regulator
BHKMAKMB_03490 2.3e-201 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
BHKMAKMB_03491 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
BHKMAKMB_03492 5.2e-50 S LrgA family
BHKMAKMB_03493 2.6e-118 yxaC M effector of murein hydrolase
BHKMAKMB_03494 1.3e-193 yxaB GM Polysaccharide pyruvyl transferase
BHKMAKMB_03495 7e-209 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
BHKMAKMB_03496 7.3e-127 gntR K transcriptional
BHKMAKMB_03497 4.6e-304 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
BHKMAKMB_03498 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
BHKMAKMB_03499 3.8e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BHKMAKMB_03500 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
BHKMAKMB_03501 3.8e-287 ahpF O Alkyl hydroperoxide reductase
BHKMAKMB_03502 6.4e-292 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
BHKMAKMB_03503 2.3e-34 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
BHKMAKMB_03504 1.3e-128 yydK K Transcriptional regulator
BHKMAKMB_03505 7.6e-13
BHKMAKMB_03506 3.3e-119 S ABC-2 family transporter protein
BHKMAKMB_03507 1.8e-110 prrC P ABC transporter
BHKMAKMB_03508 8.4e-134 yydH O Peptidase M50
BHKMAKMB_03509 7.7e-185 S Radical SAM superfamily
BHKMAKMB_03510 8e-12
BHKMAKMB_03511 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
BHKMAKMB_03512 0.0 S Uncharacterised protein conserved in bacteria (DUF2326)
BHKMAKMB_03513 3.5e-65
BHKMAKMB_03514 7.3e-280 S Calcineurin-like phosphoesterase
BHKMAKMB_03515 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BHKMAKMB_03516 1.1e-09 S YyzF-like protein
BHKMAKMB_03517 4.2e-71
BHKMAKMB_03518 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
BHKMAKMB_03520 2.1e-33 yycQ S Protein of unknown function (DUF2651)
BHKMAKMB_03521 1.6e-221 yycP
BHKMAKMB_03522 5.8e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
BHKMAKMB_03523 3.1e-86 yycN 2.3.1.128 K Acetyltransferase
BHKMAKMB_03524 5e-188 S aspartate phosphatase
BHKMAKMB_03526 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
BHKMAKMB_03527 9.7e-261 rocE E amino acid
BHKMAKMB_03528 1.7e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
BHKMAKMB_03529 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
BHKMAKMB_03530 8.4e-221 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BHKMAKMB_03531 8.7e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
BHKMAKMB_03532 7.3e-155 yycI S protein conserved in bacteria
BHKMAKMB_03533 3.6e-260 yycH S protein conserved in bacteria
BHKMAKMB_03534 0.0 vicK 2.7.13.3 T Histidine kinase
BHKMAKMB_03535 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BHKMAKMB_03540 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BHKMAKMB_03541 8e-78 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
BHKMAKMB_03542 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
BHKMAKMB_03543 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
BHKMAKMB_03545 1.9e-15 yycC K YycC-like protein
BHKMAKMB_03546 8.4e-221 yeaN P COG2807 Cyanate permease
BHKMAKMB_03547 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BHKMAKMB_03548 2.2e-73 rplI J binds to the 23S rRNA
BHKMAKMB_03549 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
BHKMAKMB_03550 2.9e-160 yybS S membrane
BHKMAKMB_03552 3.9e-84 cotF M Spore coat protein
BHKMAKMB_03553 1.4e-68 ydeP3 K Transcriptional regulator
BHKMAKMB_03554 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
BHKMAKMB_03555 1.3e-70
BHKMAKMB_03557 2.3e-240 yybO G COG0477 Permeases of the major facilitator superfamily
BHKMAKMB_03558 1e-16
BHKMAKMB_03559 1.3e-78 yybN S Protein of unknown function (DUF2712)
BHKMAKMB_03560 4.1e-125
BHKMAKMB_03561 9e-122
BHKMAKMB_03562 2e-127 S Protein of unknown function (DUF2705)
BHKMAKMB_03563 2.6e-115 V ATPases associated with a variety of cellular activities
BHKMAKMB_03564 6.2e-132
BHKMAKMB_03565 5.9e-67 yybH S SnoaL-like domain
BHKMAKMB_03566 3e-124 yybG S Pentapeptide repeat-containing protein
BHKMAKMB_03567 3.2e-220 ynfM EGP Major facilitator Superfamily
BHKMAKMB_03568 2.1e-165 yybE K Transcriptional regulator
BHKMAKMB_03569 2e-79 yjcF S Acetyltransferase (GNAT) domain
BHKMAKMB_03570 2.7e-77 yybC
BHKMAKMB_03571 3e-127 S Metallo-beta-lactamase superfamily
BHKMAKMB_03572 5.6e-77 yybA 2.3.1.57 K transcriptional
BHKMAKMB_03573 5.9e-79 yjcF S Acetyltransferase (GNAT) domain
BHKMAKMB_03574 1.5e-101 yyaS S Membrane
BHKMAKMB_03575 5.4e-100 yyaR K Acetyltransferase (GNAT) domain
BHKMAKMB_03576 5.4e-67 yyaQ S YjbR
BHKMAKMB_03577 1.7e-107 yyaP 1.5.1.3 H RibD C-terminal domain
BHKMAKMB_03578 1.7e-249 tetL EGP Major facilitator Superfamily
BHKMAKMB_03579 9.7e-44 yyaL O Highly conserved protein containing a thioredoxin domain
BHKMAKMB_03580 5.1e-61 yyaN K MerR HTH family regulatory protein
BHKMAKMB_03581 3.3e-161 yyaM EG EamA-like transporter family
BHKMAKMB_03582 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
BHKMAKMB_03583 9.5e-169 yyaK S CAAX protease self-immunity
BHKMAKMB_03584 3.8e-246 EGP Major facilitator superfamily
BHKMAKMB_03585 5.1e-96 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
BHKMAKMB_03586 4e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
BHKMAKMB_03587 3.3e-180 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
BHKMAKMB_03588 8.1e-145 xth 3.1.11.2 L exodeoxyribonuclease III
BHKMAKMB_03589 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BHKMAKMB_03590 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
BHKMAKMB_03591 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
BHKMAKMB_03592 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
BHKMAKMB_03593 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BHKMAKMB_03594 2.3e-33 yyzM S protein conserved in bacteria
BHKMAKMB_03595 8.1e-177 yyaD S Membrane
BHKMAKMB_03596 1.6e-111 yyaC S Sporulation protein YyaC
BHKMAKMB_03597 2.1e-149 spo0J K Belongs to the ParB family
BHKMAKMB_03598 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
BHKMAKMB_03599 1.5e-74 S Bacterial PH domain
BHKMAKMB_03600 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
BHKMAKMB_03601 2.2e-131 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
BHKMAKMB_03602 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
BHKMAKMB_03603 3.1e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BHKMAKMB_03604 6.5e-108 jag S single-stranded nucleic acid binding R3H
BHKMAKMB_03605 5.1e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
BHKMAKMB_03606 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
BHKMAKMB_03607 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BHKMAKMB_03608 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
BHKMAKMB_03609 2.4e-33 yaaA S S4 domain
BHKMAKMB_03610 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BHKMAKMB_03611 1.8e-37 yaaB S Domain of unknown function (DUF370)
BHKMAKMB_03612 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BHKMAKMB_03613 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BHKMAKMB_03614 6.7e-167 ygxA S Nucleotidyltransferase-like
BHKMAKMB_03615 1.5e-56 ygzB S UPF0295 protein
BHKMAKMB_03616 4e-80 perR P Belongs to the Fur family
BHKMAKMB_03617 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
BHKMAKMB_03618 1.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
BHKMAKMB_03619 8.7e-180 ygaE S Membrane
BHKMAKMB_03620 1.8e-301 ygaD V ABC transporter
BHKMAKMB_03621 1.3e-104 ygaC J Belongs to the UPF0374 family
BHKMAKMB_03622 1.5e-37 ygaB S YgaB-like protein
BHKMAKMB_03623 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
BHKMAKMB_03624 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
BHKMAKMB_03625 6.9e-36 yfhS
BHKMAKMB_03626 7.8e-212 mutY L A G-specific
BHKMAKMB_03627 5.5e-186 yfhP S membrane-bound metal-dependent
BHKMAKMB_03628 0.0 yfhO S Bacterial membrane protein YfhO
BHKMAKMB_03629 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
BHKMAKMB_03630 6.7e-172 yfhM S Alpha beta hydrolase
BHKMAKMB_03631 3.5e-51 yfhL S SdpI/YhfL protein family
BHKMAKMB_03632 9.2e-92 batE T Bacterial SH3 domain homologues
BHKMAKMB_03633 1.3e-44 yfhJ S WVELL protein
BHKMAKMB_03634 6.2e-20 sspK S reproduction
BHKMAKMB_03635 1.1e-209 yfhI EGP Major facilitator Superfamily
BHKMAKMB_03637 9.7e-52 yfhH S Protein of unknown function (DUF1811)
BHKMAKMB_03638 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
BHKMAKMB_03639 4.9e-173 yfhF S nucleoside-diphosphate sugar epimerase
BHKMAKMB_03641 2.1e-25 yfhD S YfhD-like protein
BHKMAKMB_03642 3.9e-107 yfhC C nitroreductase
BHKMAKMB_03643 1.8e-167 yfhB 5.3.3.17 S PhzF family
BHKMAKMB_03644 5.2e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BHKMAKMB_03645 3.1e-176 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BHKMAKMB_03646 6.2e-182 yfiY P ABC transporter substrate-binding protein
BHKMAKMB_03647 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BHKMAKMB_03648 3.1e-81 yfiV K transcriptional
BHKMAKMB_03649 8.7e-287 yfiU EGP Major facilitator Superfamily
BHKMAKMB_03650 3.3e-100 yfiT S Belongs to the metal hydrolase YfiT family
BHKMAKMB_03651 5.1e-221 yfiS EGP Major facilitator Superfamily
BHKMAKMB_03652 2e-109 yfiR K Transcriptional regulator
BHKMAKMB_03653 9e-198 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
BHKMAKMB_03654 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
BHKMAKMB_03655 8.3e-99 padR K transcriptional
BHKMAKMB_03656 4.6e-208 V COG0842 ABC-type multidrug transport system, permease component
BHKMAKMB_03657 9.8e-214 V ABC-2 family transporter protein
BHKMAKMB_03658 6.2e-171 V ABC transporter, ATP-binding protein
BHKMAKMB_03659 3.2e-113 KT LuxR family transcriptional regulator
BHKMAKMB_03660 1.1e-214 yxjM T Histidine kinase
BHKMAKMB_03662 1.1e-233 S Oxidoreductase
BHKMAKMB_03663 8.4e-184 G Xylose isomerase
BHKMAKMB_03664 1.8e-262 iolT EGP Major facilitator Superfamily
BHKMAKMB_03665 1.5e-177 K AraC-like ligand binding domain
BHKMAKMB_03666 5.7e-163 yfiE 1.13.11.2 S glyoxalase
BHKMAKMB_03667 9.8e-65 mhqP S DoxX
BHKMAKMB_03668 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
BHKMAKMB_03669 2.1e-310 yfiB3 V ABC transporter
BHKMAKMB_03670 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
BHKMAKMB_03671 3.2e-141 glvR K Helix-turn-helix domain, rpiR family
BHKMAKMB_03672 9.9e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
BHKMAKMB_03673 1.1e-44 yfjA S Belongs to the WXG100 family
BHKMAKMB_03674 9.2e-191 yfjB
BHKMAKMB_03675 4.1e-144 yfjC
BHKMAKMB_03676 1.8e-101 yfjD S Family of unknown function (DUF5381)
BHKMAKMB_03677 1.3e-80 S Family of unknown function (DUF5381)
BHKMAKMB_03678 4e-56 yfjF S UPF0060 membrane protein
BHKMAKMB_03679 1.2e-25 sspH S Belongs to the SspH family
BHKMAKMB_03680 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
BHKMAKMB_03681 6.4e-257 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
BHKMAKMB_03682 2.9e-197 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
BHKMAKMB_03683 1e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
BHKMAKMB_03684 1.2e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
BHKMAKMB_03685 3e-29 yfjL
BHKMAKMB_03686 3.9e-86 yfjM S Psort location Cytoplasmic, score
BHKMAKMB_03687 5.1e-192 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BHKMAKMB_03688 1.6e-39 S YfzA-like protein
BHKMAKMB_03689 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BHKMAKMB_03690 1e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BHKMAKMB_03691 1.7e-184 corA P Mediates influx of magnesium ions
BHKMAKMB_03692 4.2e-150 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
BHKMAKMB_03693 2.6e-154 pdaA G deacetylase
BHKMAKMB_03694 1.1e-26 yfjT
BHKMAKMB_03695 5.4e-222 yfkA S YfkB-like domain
BHKMAKMB_03696 6e-149 yfkC M Mechanosensitive ion channel
BHKMAKMB_03697 1.2e-146 yfkD S YfkD-like protein
BHKMAKMB_03698 6.1e-183 cax P COG0387 Ca2 H antiporter
BHKMAKMB_03699 6.9e-220 ycaD EGP COG0477 Permeases of the major facilitator superfamily
BHKMAKMB_03700 5e-08
BHKMAKMB_03701 9.7e-144 yihY S Belongs to the UPF0761 family
BHKMAKMB_03702 8.4e-51 yfkI S gas vesicle protein
BHKMAKMB_03703 2.2e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BHKMAKMB_03704 2.1e-29 yfkK S Belongs to the UPF0435 family
BHKMAKMB_03705 6.8e-207 ydiM EGP Major facilitator Superfamily
BHKMAKMB_03706 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
BHKMAKMB_03707 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
BHKMAKMB_03708 1.6e-125 yfkO C nitroreductase
BHKMAKMB_03709 1.8e-133 treR K transcriptional
BHKMAKMB_03710 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
BHKMAKMB_03711 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
BHKMAKMB_03712 1.5e-283 yfkQ EG Spore germination protein
BHKMAKMB_03713 5.1e-207 yfkR S spore germination
BHKMAKMB_03715 1.6e-194 E Spore germination protein
BHKMAKMB_03716 3.2e-256 agcS_1 E Sodium alanine symporter
BHKMAKMB_03717 6e-67 yhdN S Domain of unknown function (DUF1992)
BHKMAKMB_03718 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
BHKMAKMB_03719 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
BHKMAKMB_03720 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
BHKMAKMB_03721 2.4e-50 yflH S Protein of unknown function (DUF3243)
BHKMAKMB_03722 4.1e-19 yflI
BHKMAKMB_03723 4e-18 yflJ S Protein of unknown function (DUF2639)
BHKMAKMB_03724 9e-124 yflK S protein conserved in bacteria
BHKMAKMB_03725 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
BHKMAKMB_03726 1.3e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BHKMAKMB_03727 5.5e-152 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
BHKMAKMB_03728 8.5e-227 citM C Citrate transporter
BHKMAKMB_03730 3e-181 yflP S Tripartite tricarboxylate transporter family receptor
BHKMAKMB_03731 3.4e-118 citT T response regulator
BHKMAKMB_03732 4.8e-288 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
BHKMAKMB_03733 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
BHKMAKMB_03734 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
BHKMAKMB_03735 7.6e-58 yflT S Heat induced stress protein YflT
BHKMAKMB_03736 2.9e-24 S Protein of unknown function (DUF3212)
BHKMAKMB_03737 3.4e-169 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
BHKMAKMB_03738 4.3e-170 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BHKMAKMB_03739 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BHKMAKMB_03740 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
BHKMAKMB_03741 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
BHKMAKMB_03742 7.7e-214 G Major Facilitator Superfamily
BHKMAKMB_03743 8.5e-190 yfmJ S N-terminal domain of oxidoreductase
BHKMAKMB_03744 7.5e-82 yfmK 2.3.1.128 K acetyltransferase
BHKMAKMB_03745 6.3e-202 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
BHKMAKMB_03746 1.9e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
BHKMAKMB_03747 1.5e-209 yfmO EGP Major facilitator Superfamily
BHKMAKMB_03748 2.8e-70 yfmP K transcriptional
BHKMAKMB_03749 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
BHKMAKMB_03750 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
BHKMAKMB_03751 1.1e-113 yfmS NT chemotaxis protein
BHKMAKMB_03752 2.8e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
BHKMAKMB_03753 1.3e-241 yfnA E amino acid
BHKMAKMB_03754 7.8e-134 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
BHKMAKMB_03755 2e-206 fsr P COG0477 Permeases of the major facilitator superfamily
BHKMAKMB_03756 3.5e-190 yfnD M Nucleotide-diphospho-sugar transferase
BHKMAKMB_03757 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
BHKMAKMB_03758 3.8e-181 yfnF M Nucleotide-diphospho-sugar transferase
BHKMAKMB_03759 1.9e-172 yfnG 4.2.1.45 M dehydratase
BHKMAKMB_03760 2.1e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
BHKMAKMB_03761 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
BHKMAKMB_03762 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
BHKMAKMB_03763 3.6e-199 yetN S Protein of unknown function (DUF3900)
BHKMAKMB_03764 7.8e-213 yetM CH FAD binding domain
BHKMAKMB_03765 6.4e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
BHKMAKMB_03766 5.4e-159 yetK EG EamA-like transporter family
BHKMAKMB_03767 5.3e-105 yetJ S Belongs to the BI1 family
BHKMAKMB_03768 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
BHKMAKMB_03769 4.4e-43 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
BHKMAKMB_03770 2.2e-89 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
BHKMAKMB_03771 2.2e-34
BHKMAKMB_03772 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
BHKMAKMB_03773 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
BHKMAKMB_03774 6.1e-123 yetF S membrane
BHKMAKMB_03775 3.3e-258 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
BHKMAKMB_03776 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
BHKMAKMB_03777 1.3e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
BHKMAKMB_03778 9.6e-291 lplA G Bacterial extracellular solute-binding protein
BHKMAKMB_03779 0.0 yetA
BHKMAKMB_03780 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
BHKMAKMB_03781 3e-124 yesY E GDSL-like Lipase/Acylhydrolase
BHKMAKMB_03782 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
BHKMAKMB_03783 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
BHKMAKMB_03784 1e-113 yesV S Protein of unknown function, DUF624
BHKMAKMB_03785 8.9e-132 yesU S Domain of unknown function (DUF1961)
BHKMAKMB_03786 3.8e-133 E GDSL-like Lipase/Acylhydrolase
BHKMAKMB_03787 0.0 yesS K Transcriptional regulator
BHKMAKMB_03788 1.6e-199 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
BHKMAKMB_03789 1.3e-165 yesQ P Binding-protein-dependent transport system inner membrane component
BHKMAKMB_03790 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
BHKMAKMB_03791 5e-248 yesO G Bacterial extracellular solute-binding protein
BHKMAKMB_03792 2.9e-204 yesN K helix_turn_helix, arabinose operon control protein
BHKMAKMB_03793 0.0 yesM 2.7.13.3 T Histidine kinase
BHKMAKMB_03794 4.4e-104 yesL S Protein of unknown function, DUF624
BHKMAKMB_03796 4.2e-103 yesJ K Acetyltransferase (GNAT) family
BHKMAKMB_03797 5.2e-104 cotJC P Spore Coat
BHKMAKMB_03798 1.5e-45 cotJB S CotJB protein
BHKMAKMB_03799 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
BHKMAKMB_03800 2.2e-159 yesF GM NAD(P)H-binding
BHKMAKMB_03801 9.7e-82 yesE S SnoaL-like domain
BHKMAKMB_03802 1.2e-103 dhaR3 K Transcriptional regulator
BHKMAKMB_03804 9.4e-127 yeeN K transcriptional regulatory protein
BHKMAKMB_03806 5.5e-214 S Tetratricopeptide repeat
BHKMAKMB_03807 1.8e-192 3.4.24.40 CO amine dehydrogenase activity
BHKMAKMB_03808 0.0 L nucleic acid phosphodiester bond hydrolysis
BHKMAKMB_03809 5.5e-83 S Protein of unknown function, DUF600
BHKMAKMB_03810 6.2e-31 S Colicin immunity protein / pyocin immunity protein
BHKMAKMB_03812 1.8e-212 pstS P T5orf172
BHKMAKMB_03813 0.0 yeeB L DEAD-like helicases superfamily
BHKMAKMB_03814 0.0 yeeA V Type II restriction enzyme, methylase subunits
BHKMAKMB_03815 3.2e-53 L Resolvase, N terminal domain
BHKMAKMB_03816 3.2e-98 L Recombinase
BHKMAKMB_03817 1.2e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BHKMAKMB_03818 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
BHKMAKMB_03819 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BHKMAKMB_03820 4e-156 yerO K Transcriptional regulator
BHKMAKMB_03821 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BHKMAKMB_03822 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
BHKMAKMB_03823 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BHKMAKMB_03824 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BHKMAKMB_03825 1.6e-123 sapB S MgtC SapB transporter
BHKMAKMB_03826 1.1e-197 yerI S homoserine kinase type II (protein kinase fold)
BHKMAKMB_03827 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
BHKMAKMB_03828 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BHKMAKMB_03829 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
BHKMAKMB_03830 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BHKMAKMB_03832 3.2e-305 yerD 1.4.7.1 E Belongs to the glutamate synthase family
BHKMAKMB_03833 4.8e-51 yerC S protein conserved in bacteria
BHKMAKMB_03834 8.8e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
BHKMAKMB_03835 0.0 yerA 3.5.4.2 F adenine deaminase
BHKMAKMB_03836 2.7e-27 S Protein of unknown function (DUF2892)
BHKMAKMB_03837 2.3e-232 yjeH E Amino acid permease
BHKMAKMB_03838 3.5e-73 K helix_turn_helix ASNC type
BHKMAKMB_03839 1.7e-235 purD 6.3.4.13 F Belongs to the GARS family
BHKMAKMB_03840 1.2e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
BHKMAKMB_03841 1.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BHKMAKMB_03842 7.6e-178 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
BHKMAKMB_03843 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BHKMAKMB_03844 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BHKMAKMB_03845 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BHKMAKMB_03846 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BHKMAKMB_03847 1.2e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
BHKMAKMB_03848 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BHKMAKMB_03849 7e-217 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BHKMAKMB_03850 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BHKMAKMB_03851 8e-28 yebG S NETI protein
BHKMAKMB_03852 4e-93 yebE S UPF0316 protein
BHKMAKMB_03854 1.1e-118 yebC M Membrane
BHKMAKMB_03855 6e-212 pbuG S permease
BHKMAKMB_03856 3.7e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
BHKMAKMB_03857 0.0 yebA E COG1305 Transglutaminase-like enzymes
BHKMAKMB_03858 9.5e-225 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
BHKMAKMB_03859 1.6e-177 yeaC S COG0714 MoxR-like ATPases
BHKMAKMB_03860 7.6e-155 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BHKMAKMB_03861 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
BHKMAKMB_03862 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
BHKMAKMB_03863 2.4e-181 yeaA S Protein of unknown function (DUF4003)
BHKMAKMB_03864 9.5e-160 ydjP I Alpha/beta hydrolase family
BHKMAKMB_03865 1.4e-34 ydjO S Cold-inducible protein YdjO
BHKMAKMB_03867 4.4e-157 ydjN U Involved in the tonB-independent uptake of proteins
BHKMAKMB_03868 4.5e-64 ydjM M Lytic transglycolase
BHKMAKMB_03869 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
BHKMAKMB_03870 2.7e-258 iolT EGP Major facilitator Superfamily
BHKMAKMB_03871 4.7e-196 S Ion transport 2 domain protein
BHKMAKMB_03872 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
BHKMAKMB_03873 1.6e-137 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
BHKMAKMB_03874 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BHKMAKMB_03875 5.1e-114 pspA KT Phage shock protein A
BHKMAKMB_03876 1.5e-175 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
BHKMAKMB_03877 7.1e-256 gutA G MFS/sugar transport protein
BHKMAKMB_03878 3.8e-201 gutB 1.1.1.14 E Dehydrogenase
BHKMAKMB_03879 0.0 K NB-ARC domain
BHKMAKMB_03880 1.1e-08 ydjC S Abhydrolase domain containing 18
BHKMAKMB_03881 4.9e-257 J LlaJI restriction endonuclease
BHKMAKMB_03882 1.2e-199 V AAA domain (dynein-related subfamily)
BHKMAKMB_03884 1.6e-232 ydiP 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
BHKMAKMB_03885 1.1e-250 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
BHKMAKMB_03886 6.4e-66 KL Phage plasmid primase P4 family
BHKMAKMB_03888 1.2e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
BHKMAKMB_03889 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BHKMAKMB_03890 7.9e-129 ydiL S CAAX protease self-immunity
BHKMAKMB_03891 2.9e-27 ydiK S Domain of unknown function (DUF4305)
BHKMAKMB_03892 8.4e-126 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BHKMAKMB_03893 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
BHKMAKMB_03894 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BHKMAKMB_03895 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
BHKMAKMB_03896 0.0 ydiF S ABC transporter
BHKMAKMB_03897 3.6e-188 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BHKMAKMB_03898 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
BHKMAKMB_03899 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
BHKMAKMB_03900 9.1e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
BHKMAKMB_03901 4.6e-185 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BHKMAKMB_03903 7.8e-08
BHKMAKMB_03904 2.9e-76 ctsR K Belongs to the CtsR family
BHKMAKMB_03905 4.7e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
BHKMAKMB_03906 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
BHKMAKMB_03907 0.0 clpC O Belongs to the ClpA ClpB family
BHKMAKMB_03908 9.6e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BHKMAKMB_03909 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BHKMAKMB_03910 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
BHKMAKMB_03911 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
BHKMAKMB_03912 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
BHKMAKMB_03913 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BHKMAKMB_03914 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
BHKMAKMB_03915 4.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
BHKMAKMB_03916 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BHKMAKMB_03917 1.2e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BHKMAKMB_03918 1.2e-88 yacP S RNA-binding protein containing a PIN domain
BHKMAKMB_03919 1.5e-115 sigH K Belongs to the sigma-70 factor family
BHKMAKMB_03920 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
BHKMAKMB_03921 4.9e-96 nusG K Participates in transcription elongation, termination and antitermination
BHKMAKMB_03922 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BHKMAKMB_03923 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
BHKMAKMB_03924 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BHKMAKMB_03925 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
BHKMAKMB_03926 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
BHKMAKMB_03927 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BHKMAKMB_03928 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BHKMAKMB_03929 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
BHKMAKMB_03930 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BHKMAKMB_03931 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
BHKMAKMB_03932 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BHKMAKMB_03933 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BHKMAKMB_03934 9.1e-186 ybaC 3.4.11.5 S Alpha/beta hydrolase family
BHKMAKMB_03935 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
BHKMAKMB_03936 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BHKMAKMB_03937 3e-105 rplD J Forms part of the polypeptide exit tunnel
BHKMAKMB_03938 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
BHKMAKMB_03939 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BHKMAKMB_03940 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BHKMAKMB_03941 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BHKMAKMB_03942 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BHKMAKMB_03943 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BHKMAKMB_03944 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
BHKMAKMB_03945 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BHKMAKMB_03946 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BHKMAKMB_03947 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BHKMAKMB_03948 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BHKMAKMB_03949 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BHKMAKMB_03950 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BHKMAKMB_03951 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BHKMAKMB_03952 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BHKMAKMB_03953 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BHKMAKMB_03954 1.9e-23 rpmD J Ribosomal protein L30
BHKMAKMB_03955 1.8e-72 rplO J binds to the 23S rRNA
BHKMAKMB_03956 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
BHKMAKMB_03957 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
BHKMAKMB_03958 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
BHKMAKMB_03959 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BHKMAKMB_03960 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
BHKMAKMB_03961 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BHKMAKMB_03962 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BHKMAKMB_03963 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BHKMAKMB_03964 3.6e-58 rplQ J Ribosomal protein L17
BHKMAKMB_03965 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BHKMAKMB_03966 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BHKMAKMB_03967 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BHKMAKMB_03968 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
BHKMAKMB_03969 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BHKMAKMB_03970 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
BHKMAKMB_03971 8.2e-145 ybaJ Q Methyltransferase domain
BHKMAKMB_03972 9.7e-66 ybaK S Protein of unknown function (DUF2521)
BHKMAKMB_03973 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
BHKMAKMB_03974 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
BHKMAKMB_03975 1.2e-84 gerD
BHKMAKMB_03976 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
BHKMAKMB_03977 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
BHKMAKMB_03978 3.4e-31 csfB S Inhibitor of sigma-G Gin
BHKMAKMB_03979 4.7e-103 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
BHKMAKMB_03980 4.5e-203 yaaN P Belongs to the TelA family
BHKMAKMB_03981 1.1e-275 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
BHKMAKMB_03982 3.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BHKMAKMB_03983 2.2e-54 yaaQ S protein conserved in bacteria
BHKMAKMB_03984 1.5e-71 yaaR S protein conserved in bacteria
BHKMAKMB_03985 2.2e-182 holB 2.7.7.7 L DNA polymerase III
BHKMAKMB_03986 2.1e-146 yaaT S stage 0 sporulation protein
BHKMAKMB_03987 4.8e-31 yabA L Involved in initiation control of chromosome replication
BHKMAKMB_03988 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
BHKMAKMB_03989 1.5e-49 yazA L endonuclease containing a URI domain
BHKMAKMB_03990 4.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BHKMAKMB_03991 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
BHKMAKMB_03992 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BHKMAKMB_03993 1.8e-144 tatD L hydrolase, TatD
BHKMAKMB_03994 4.3e-194 rpfB GH23 T protein conserved in bacteria
BHKMAKMB_03995 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BHKMAKMB_03996 2.4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
BHKMAKMB_03997 3.3e-137 yabG S peptidase
BHKMAKMB_03998 7.8e-39 veg S protein conserved in bacteria
BHKMAKMB_03999 8.3e-27 sspF S DNA topological change
BHKMAKMB_04000 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BHKMAKMB_04001 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
BHKMAKMB_04002 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
BHKMAKMB_04003 2.3e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
BHKMAKMB_04004 6.6e-230 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BHKMAKMB_04005 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BHKMAKMB_04006 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BHKMAKMB_04007 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
BHKMAKMB_04008 2.4e-39 yabK S Peptide ABC transporter permease
BHKMAKMB_04009 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BHKMAKMB_04010 1.5e-92 spoVT K stage V sporulation protein
BHKMAKMB_04011 2.4e-287 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
BHKMAKMB_04012 2.7e-245 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
BHKMAKMB_04013 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
BHKMAKMB_04014 1.5e-49 yabP S Sporulation protein YabP
BHKMAKMB_04015 3.9e-108 yabQ S spore cortex biosynthesis protein
BHKMAKMB_04016 1.1e-44 divIC D Septum formation initiator
BHKMAKMB_04017 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
BHKMAKMB_04020 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
BHKMAKMB_04021 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
BHKMAKMB_04022 6.7e-187 KLT serine threonine protein kinase
BHKMAKMB_04023 3.5e-274 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
BHKMAKMB_04024 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
BHKMAKMB_04025 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BHKMAKMB_04026 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BHKMAKMB_04027 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BHKMAKMB_04028 1.6e-160 yacD 5.2.1.8 O peptidyl-prolyl isomerase
BHKMAKMB_04029 8.9e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
BHKMAKMB_04030 4.7e-271 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BHKMAKMB_04031 1.5e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
BHKMAKMB_04032 1.6e-168 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
BHKMAKMB_04033 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BHKMAKMB_04034 8.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BHKMAKMB_04035 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BHKMAKMB_04036 4.1e-30 yazB K transcriptional
BHKMAKMB_04037 3.7e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BHKMAKMB_04038 1.3e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
BHKMAKMB_04039 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
BHKMAKMB_04040 7.9e-32 yaaL S Protein of unknown function (DUF2508)
BHKMAKMB_04041 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BHKMAKMB_04042 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BHKMAKMB_04043 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BHKMAKMB_04044 1e-84 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
BHKMAKMB_04045 2.4e-98 yaaI Q COG1335 Amidases related to nicotinamidase
BHKMAKMB_04046 5.6e-215 yaaH M Glycoside Hydrolase Family
BHKMAKMB_04047 3.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
BHKMAKMB_04048 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
BHKMAKMB_04049 1.3e-09
BHKMAKMB_04050 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BHKMAKMB_04051 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BHKMAKMB_04052 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BHKMAKMB_04053 5.2e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
BHKMAKMB_04054 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
BHKMAKMB_04055 2.7e-182 yaaC S YaaC-like Protein
BHKMAKMB_04060 2e-08
BHKMAKMB_04068 2e-08

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)