ORF_ID e_value Gene_name EC_number CAZy COGs Description
MCDHIGFA_00002 1.8e-131 sagD S YcaO cyclodehydratase, ATP-ad Mg2+-binding
MCDHIGFA_00003 5.1e-56
MCDHIGFA_00004 3.2e-49 sagB C Nitroreductase family
MCDHIGFA_00005 7.5e-236 S Uncharacterized protein conserved in bacteria (DUF2325)
MCDHIGFA_00006 1.5e-112 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MCDHIGFA_00007 6.4e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
MCDHIGFA_00008 7.8e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MCDHIGFA_00009 7.4e-128 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MCDHIGFA_00010 1.6e-194 I transferase activity, transferring acyl groups other than amino-acyl groups
MCDHIGFA_00011 8e-136 S PFAM Archaeal ATPase
MCDHIGFA_00012 1.6e-82 M NlpC/P60 family
MCDHIGFA_00013 2.4e-132 cobQ S glutamine amidotransferase
MCDHIGFA_00015 1.8e-66 L RelB antitoxin
MCDHIGFA_00016 6.5e-44 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
MCDHIGFA_00017 1.3e-41 yoeB S YoeB-like toxin of bacterial type II toxin-antitoxin system
MCDHIGFA_00018 4.8e-252 yifK E Amino acid permease
MCDHIGFA_00019 7e-270 V ABC-type multidrug transport system, ATPase and permease components
MCDHIGFA_00021 2.7e-77 K DNA-templated transcription, initiation
MCDHIGFA_00022 3e-26
MCDHIGFA_00024 7.6e-16 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
MCDHIGFA_00025 1.7e-170 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
MCDHIGFA_00026 1.6e-35
MCDHIGFA_00027 6.3e-100 scrR K Periplasmic binding protein domain
MCDHIGFA_00028 1.5e-91 F Nucleoside 2-deoxyribosyltransferase
MCDHIGFA_00029 1.9e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
MCDHIGFA_00030 5.2e-163
MCDHIGFA_00031 0.0 ydgH S MMPL family
MCDHIGFA_00032 6.6e-99 yobS K Bacterial regulatory proteins, tetR family
MCDHIGFA_00033 8.8e-149 3.5.2.6 V Beta-lactamase enzyme family
MCDHIGFA_00034 5.2e-154 corA P CorA-like Mg2+ transporter protein
MCDHIGFA_00035 2.5e-239 G Bacterial extracellular solute-binding protein
MCDHIGFA_00036 3.2e-258 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
MCDHIGFA_00037 6.1e-146 gtsC P Binding-protein-dependent transport system inner membrane component
MCDHIGFA_00038 1.6e-157 gtsB P ABC-type sugar transport systems, permease components
MCDHIGFA_00039 1.9e-203 malK P ATPases associated with a variety of cellular activities
MCDHIGFA_00040 7e-283 pipD E Dipeptidase
MCDHIGFA_00041 1.9e-158 endA F DNA RNA non-specific endonuclease
MCDHIGFA_00042 3.2e-183 dnaQ 2.7.7.7 L EXOIII
MCDHIGFA_00043 2e-157 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MCDHIGFA_00044 3e-116 yviA S Protein of unknown function (DUF421)
MCDHIGFA_00045 1.1e-72 S Protein of unknown function (DUF3290)
MCDHIGFA_00046 9e-141 pnuC H nicotinamide mononucleotide transporter
MCDHIGFA_00047 3e-13
MCDHIGFA_00048 4.6e-129 S PAS domain
MCDHIGFA_00049 5.1e-274 V ABC transporter transmembrane region
MCDHIGFA_00050 2.1e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
MCDHIGFA_00051 7.7e-129 T Transcriptional regulatory protein, C terminal
MCDHIGFA_00052 2.6e-247 T GHKL domain
MCDHIGFA_00053 2.9e-88 S Peptidase propeptide and YPEB domain
MCDHIGFA_00054 2.6e-101 S Peptidase propeptide and YPEB domain
MCDHIGFA_00055 3.7e-96 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
MCDHIGFA_00056 2.1e-76 yybA 2.3.1.57 K Transcriptional regulator
MCDHIGFA_00057 0.0 oppA3 E ABC transporter, substratebinding protein
MCDHIGFA_00058 9.9e-62 ypaA S Protein of unknown function (DUF1304)
MCDHIGFA_00059 2.5e-101 S Peptidase propeptide and YPEB domain
MCDHIGFA_00060 4.4e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MCDHIGFA_00061 2.1e-171 coaA 2.7.1.33 F Pantothenic acid kinase
MCDHIGFA_00062 2.7e-97 E GDSL-like Lipase/Acylhydrolase
MCDHIGFA_00063 1.2e-74 yjcF S Acetyltransferase (GNAT) domain
MCDHIGFA_00064 1.5e-144 aatB ET ABC transporter substrate-binding protein
MCDHIGFA_00065 7.1e-107 glnQ 3.6.3.21 E ABC transporter
MCDHIGFA_00066 8.5e-111 glnP P ABC transporter permease
MCDHIGFA_00067 0.0 helD 3.6.4.12 L DNA helicase
MCDHIGFA_00068 2.7e-124 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
MCDHIGFA_00069 1.4e-126 pgm3 G Phosphoglycerate mutase family
MCDHIGFA_00070 1.2e-241 S response to antibiotic
MCDHIGFA_00071 2.9e-125
MCDHIGFA_00072 0.0 3.6.3.8 P P-type ATPase
MCDHIGFA_00073 5e-15 S Domain of Unknown Function with PDB structure (DUF3850)
MCDHIGFA_00075 2.9e-12
MCDHIGFA_00076 2e-18 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
MCDHIGFA_00077 6.4e-40 3.2.1.18 GH33 M Rib/alpha-like repeat
MCDHIGFA_00078 1.5e-16 S Transposase C of IS166 homeodomain
MCDHIGFA_00079 8.4e-13 L PFAM IS66 Orf2 family protein
MCDHIGFA_00081 1.3e-30
MCDHIGFA_00082 3.6e-69 T Toxin-antitoxin system, toxin component, MazF family
MCDHIGFA_00083 4.3e-103 L Integrase
MCDHIGFA_00084 1.2e-140 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MCDHIGFA_00085 1e-104 pncA Q Isochorismatase family
MCDHIGFA_00087 2e-35
MCDHIGFA_00088 6.4e-27
MCDHIGFA_00089 7.8e-47 S Lantibiotic dehydratase, C terminus
MCDHIGFA_00090 9.8e-21 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
MCDHIGFA_00091 1e-60 S SLAP domain
MCDHIGFA_00092 3.9e-181 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MCDHIGFA_00093 3.9e-187 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MCDHIGFA_00094 4.9e-159 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MCDHIGFA_00095 5.8e-180 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MCDHIGFA_00096 5.1e-17
MCDHIGFA_00097 5.9e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MCDHIGFA_00098 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MCDHIGFA_00099 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MCDHIGFA_00100 2.2e-133 comFC S Competence protein
MCDHIGFA_00101 1.6e-246 comFA L Helicase C-terminal domain protein
MCDHIGFA_00102 1.9e-118 yvyE 3.4.13.9 S YigZ family
MCDHIGFA_00103 1.3e-210 tagO 2.7.8.33, 2.7.8.35 M transferase
MCDHIGFA_00104 1.3e-219 rny S Endoribonuclease that initiates mRNA decay
MCDHIGFA_00105 8.5e-196 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MCDHIGFA_00106 1.1e-95 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MCDHIGFA_00107 5.2e-97 ymfM S Helix-turn-helix domain
MCDHIGFA_00108 1.4e-133 IQ Enoyl-(Acyl carrier protein) reductase
MCDHIGFA_00109 3.9e-237 S Peptidase M16
MCDHIGFA_00110 5.9e-222 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
MCDHIGFA_00111 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MCDHIGFA_00112 1.7e-69 WQ51_03320 S Protein of unknown function (DUF1149)
MCDHIGFA_00113 4.2e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MCDHIGFA_00114 2.6e-214 yubA S AI-2E family transporter
MCDHIGFA_00115 2.2e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
MCDHIGFA_00116 2.2e-201 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
MCDHIGFA_00117 2.5e-92 S SNARE associated Golgi protein
MCDHIGFA_00118 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
MCDHIGFA_00119 5.4e-172 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MCDHIGFA_00120 3.8e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MCDHIGFA_00121 1.2e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
MCDHIGFA_00122 3.6e-111 yjbK S CYTH
MCDHIGFA_00123 6e-114 yjbH Q Thioredoxin
MCDHIGFA_00124 3.8e-159 coiA 3.6.4.12 S Competence protein
MCDHIGFA_00125 5.5e-138 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MCDHIGFA_00126 6.1e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MCDHIGFA_00127 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MCDHIGFA_00128 8.5e-41 ptsH G phosphocarrier protein HPR
MCDHIGFA_00129 2.8e-135
MCDHIGFA_00130 2.4e-124 luxT K Bacterial regulatory proteins, tetR family
MCDHIGFA_00131 2.7e-123 yoaK S Protein of unknown function (DUF1275)
MCDHIGFA_00132 1.6e-227 L COG3547 Transposase and inactivated derivatives
MCDHIGFA_00133 7e-240 L Transposase DDE domain
MCDHIGFA_00134 2.6e-17 V Transport permease protein
MCDHIGFA_00135 2.5e-62 yfiL V ABC transporter
MCDHIGFA_00137 1.3e-49 arbZ I Phosphate acyltransferases
MCDHIGFA_00138 1.8e-86 arbZ I Phosphate acyltransferases
MCDHIGFA_00139 1.4e-36 S Cytochrome B5
MCDHIGFA_00141 1.3e-118
MCDHIGFA_00142 1.2e-57 L Transposase
MCDHIGFA_00143 8.7e-154 L Transposase
MCDHIGFA_00144 5.4e-228 L COG2963 Transposase and inactivated derivatives
MCDHIGFA_00145 2.9e-152 L Belongs to the 'phage' integrase family
MCDHIGFA_00146 1.1e-34 S Protein of unknown function (DUF2508)
MCDHIGFA_00147 1.6e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MCDHIGFA_00148 8.2e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MCDHIGFA_00149 2.4e-35 M lipopolysaccharide 3-alpha-galactosyltransferase activity
MCDHIGFA_00150 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MCDHIGFA_00151 2.2e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MCDHIGFA_00152 9e-26
MCDHIGFA_00153 1.3e-116 rsmC 2.1.1.172 J Methyltransferase
MCDHIGFA_00154 6e-141 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
MCDHIGFA_00155 1.8e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MCDHIGFA_00156 7e-84 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MCDHIGFA_00157 1.7e-12 GT2,GT4 M family 8
MCDHIGFA_00158 2.2e-61 L An automated process has identified a potential problem with this gene model
MCDHIGFA_00159 7.5e-118 phoU P Plays a role in the regulation of phosphate uptake
MCDHIGFA_00160 7.8e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MCDHIGFA_00161 5e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MCDHIGFA_00162 1.2e-155 pstA P Phosphate transport system permease protein PstA
MCDHIGFA_00163 3.9e-163 pstC P probably responsible for the translocation of the substrate across the membrane
MCDHIGFA_00164 2.8e-157 pstS P Phosphate
MCDHIGFA_00165 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MCDHIGFA_00166 2e-68 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MCDHIGFA_00167 1.1e-101 nusG K Participates in transcription elongation, termination and antitermination
MCDHIGFA_00168 3.6e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MCDHIGFA_00169 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MCDHIGFA_00170 1.7e-287 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
MCDHIGFA_00171 1.7e-34
MCDHIGFA_00172 4.2e-95 sigH K Belongs to the sigma-70 factor family
MCDHIGFA_00173 6.6e-139 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MCDHIGFA_00174 2.3e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MCDHIGFA_00175 7.5e-277 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MCDHIGFA_00176 1.9e-291 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MCDHIGFA_00177 7.8e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MCDHIGFA_00178 1.8e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
MCDHIGFA_00179 1.9e-52
MCDHIGFA_00180 1.9e-266 pepC 3.4.22.40 E Peptidase C1-like family
MCDHIGFA_00181 8.1e-51
MCDHIGFA_00182 1.1e-183 S AAA domain
MCDHIGFA_00183 1.2e-126 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MCDHIGFA_00184 1.4e-23
MCDHIGFA_00185 5.1e-162 czcD P cation diffusion facilitator family transporter
MCDHIGFA_00186 3.7e-125 gpmB G Belongs to the phosphoglycerate mutase family
MCDHIGFA_00187 6.4e-134 S membrane transporter protein
MCDHIGFA_00188 2.5e-118 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MCDHIGFA_00189 3.3e-106 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
MCDHIGFA_00190 7e-80 K Acetyltransferase (GNAT) domain
MCDHIGFA_00191 2.1e-149 M Belongs to the glycosyl hydrolase 28 family
MCDHIGFA_00192 3.2e-31 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MCDHIGFA_00193 4.7e-114 3.6.1.27 I Acid phosphatase homologues
MCDHIGFA_00194 2.2e-97 D VirC1 protein
MCDHIGFA_00196 3.6e-70 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MCDHIGFA_00197 7.3e-86 3.4.21.96 S SLAP domain
MCDHIGFA_00198 5.8e-79 fhaB M Rib/alpha-like repeat
MCDHIGFA_00199 1.4e-165 mdtG EGP Major facilitator Superfamily
MCDHIGFA_00201 2.5e-42 S cog cog1373
MCDHIGFA_00202 7e-23 S PFAM Archaeal ATPase
MCDHIGFA_00203 5.2e-25 srtA 3.4.22.70 M sortase family
MCDHIGFA_00205 7.9e-42 M domain protein
MCDHIGFA_00206 3.4e-34 M domain protein
MCDHIGFA_00210 3.1e-141 U TraM recognition site of TraD and TraG
MCDHIGFA_00211 2.1e-33 I mechanosensitive ion channel activity
MCDHIGFA_00213 3.8e-15
MCDHIGFA_00214 4e-159 trsE S COG0433 Predicted ATPase
MCDHIGFA_00215 9.4e-33 M Peptidase family M23
MCDHIGFA_00218 3.4e-17 CO COG0526, thiol-disulfide isomerase and thioredoxins
MCDHIGFA_00224 3.4e-52 S COG0790 FOG TPR repeat, SEL1 subfamily
MCDHIGFA_00225 2.5e-38 L Protein of unknown function (DUF3991)
MCDHIGFA_00226 4.2e-112 S Fic/DOC family
MCDHIGFA_00228 4.6e-48 E Pfam:DUF955
MCDHIGFA_00229 1.7e-23 relB L Addiction module antitoxin, RelB DinJ family
MCDHIGFA_00230 5.6e-18 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
MCDHIGFA_00232 1.2e-134 topA2 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MCDHIGFA_00233 1.1e-23 S CAAX protease self-immunity
MCDHIGFA_00234 1.1e-34
MCDHIGFA_00235 1e-66 doc S Fic/DOC family
MCDHIGFA_00237 5.3e-87 K sequence-specific DNA binding
MCDHIGFA_00238 4e-128 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MCDHIGFA_00239 7.8e-73
MCDHIGFA_00240 7.3e-86
MCDHIGFA_00241 2e-58 hsdS 3.1.21.3 V PFAM restriction modification system DNA specificity domain
MCDHIGFA_00242 2.3e-10 spaC2 V Lanthionine synthetase C-like protein
MCDHIGFA_00243 4.2e-208 S Uncharacterized protein conserved in bacteria (DUF2325)
MCDHIGFA_00244 8.7e-232 G Bacterial extracellular solute-binding protein
MCDHIGFA_00245 3.8e-161 2.7.7.12 C Domain of unknown function (DUF4931)
MCDHIGFA_00246 1.8e-167 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MCDHIGFA_00247 9e-127 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MCDHIGFA_00248 0.0 kup P Transport of potassium into the cell
MCDHIGFA_00249 2.8e-176 rihB 3.2.2.1 F Nucleoside
MCDHIGFA_00250 9.8e-132 ydhQ K UbiC transcription regulator-associated domain protein
MCDHIGFA_00251 2.7e-154 S hydrolase
MCDHIGFA_00252 1e-60 S Enterocin A Immunity
MCDHIGFA_00253 2.5e-138 glcR K DeoR C terminal sensor domain
MCDHIGFA_00254 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
MCDHIGFA_00255 7.1e-158 rssA S Phospholipase, patatin family
MCDHIGFA_00256 7.5e-149 S hydrolase
MCDHIGFA_00257 0.0 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
MCDHIGFA_00258 6.4e-148 glvR K Helix-turn-helix domain, rpiR family
MCDHIGFA_00259 7e-81
MCDHIGFA_00260 4.2e-86 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MCDHIGFA_00261 2.1e-39
MCDHIGFA_00262 2.3e-119 C nitroreductase
MCDHIGFA_00263 2.2e-249 yhdP S Transporter associated domain
MCDHIGFA_00264 3.4e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MCDHIGFA_00265 0.0 1.3.5.4 C FAD binding domain
MCDHIGFA_00266 2.9e-88 L PFAM transposase, IS4 family protein
MCDHIGFA_00267 5.8e-49 L PFAM transposase, IS4 family protein
MCDHIGFA_00268 0.0 1.3.5.4 C FAD binding domain
MCDHIGFA_00269 3.7e-230 potE E amino acid
MCDHIGFA_00270 4.7e-131 M Glycosyl hydrolases family 25
MCDHIGFA_00271 2.8e-211 yfmL 3.6.4.13 L DEAD DEAH box helicase
MCDHIGFA_00272 8.9e-248 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MCDHIGFA_00274 2e-216 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MCDHIGFA_00275 3.1e-87 gtcA S Teichoic acid glycosylation protein
MCDHIGFA_00276 4.1e-80 fld C Flavodoxin
MCDHIGFA_00277 5.4e-24 oapA 2.7.11.1, 2.7.7.7, 3.1.26.12 UW LPXTG-motif cell wall anchor domain protein
MCDHIGFA_00278 1.4e-24 dam2 2.1.1.72 L DNA methyltransferase
MCDHIGFA_00281 7.6e-30 scrR K Periplasmic binding protein domain
MCDHIGFA_00282 8e-38
MCDHIGFA_00283 3.7e-111 K WHG domain
MCDHIGFA_00284 6.4e-96 nqr 1.5.1.36 S NADPH-dependent FMN reductase
MCDHIGFA_00285 2e-97 azr 1.5.1.36 S NADPH-dependent FMN reductase
MCDHIGFA_00286 6e-151 3.1.3.48 T Tyrosine phosphatase family
MCDHIGFA_00287 2.8e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MCDHIGFA_00288 3e-53 cvpA S Colicin V production protein
MCDHIGFA_00289 2.7e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
MCDHIGFA_00290 5e-148 noc K Belongs to the ParB family
MCDHIGFA_00291 3.4e-138 soj D Sporulation initiation inhibitor
MCDHIGFA_00292 3.8e-154 spo0J K Belongs to the ParB family
MCDHIGFA_00293 6.2e-44 yyzM S Bacterial protein of unknown function (DUF951)
MCDHIGFA_00294 3.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MCDHIGFA_00295 4.6e-135 XK27_01040 S Protein of unknown function (DUF1129)
MCDHIGFA_00296 8.7e-304 V ABC transporter, ATP-binding protein
MCDHIGFA_00297 0.0 V ABC transporter
MCDHIGFA_00299 9.6e-121 K response regulator
MCDHIGFA_00300 1.3e-207 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
MCDHIGFA_00301 5.5e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MCDHIGFA_00302 8e-145 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
MCDHIGFA_00303 6.2e-54 S Enterocin A Immunity
MCDHIGFA_00304 2.5e-33
MCDHIGFA_00305 9.5e-26
MCDHIGFA_00306 1e-24
MCDHIGFA_00307 4.2e-272 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
MCDHIGFA_00308 2.3e-220 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
MCDHIGFA_00309 1.2e-213 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
MCDHIGFA_00310 6.4e-11
MCDHIGFA_00311 4.3e-68
MCDHIGFA_00313 9.2e-220 S CAAX protease self-immunity
MCDHIGFA_00315 2.3e-210 S CAAX protease self-immunity
MCDHIGFA_00317 2.9e-238 2.7.13.3 T GHKL domain
MCDHIGFA_00318 7.3e-136 K LytTr DNA-binding domain
MCDHIGFA_00319 1.4e-178 blpT
MCDHIGFA_00321 9.6e-211 M Glycosyl transferase family 2
MCDHIGFA_00322 1.9e-30
MCDHIGFA_00323 1.1e-31 S Bacteriocin class II with double-glycine leader peptide
MCDHIGFA_00325 2e-29
MCDHIGFA_00327 1.4e-51 L Helix-turn-helix domain
MCDHIGFA_00328 3.4e-79 L Helix-turn-helix domain
MCDHIGFA_00329 1e-14 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
MCDHIGFA_00330 2.8e-98 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
MCDHIGFA_00331 2.3e-59 hxlR K Transcriptional regulator, HxlR family
MCDHIGFA_00332 3.2e-197 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
MCDHIGFA_00333 2.7e-96 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MCDHIGFA_00334 1e-95
MCDHIGFA_00335 1.5e-145 yfeO P Voltage gated chloride channel
MCDHIGFA_00336 8.9e-184 5.3.3.2 C FMN-dependent dehydrogenase
MCDHIGFA_00337 3.1e-51
MCDHIGFA_00338 4.7e-42
MCDHIGFA_00339 7.5e-233 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MCDHIGFA_00340 7.8e-299 ybeC E amino acid
MCDHIGFA_00341 2.6e-157 S Sucrose-6F-phosphate phosphohydrolase
MCDHIGFA_00342 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
MCDHIGFA_00343 2.5e-39 rpmE2 J Ribosomal protein L31
MCDHIGFA_00344 1.7e-262 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MCDHIGFA_00345 2.9e-247 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MCDHIGFA_00346 1e-57 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MCDHIGFA_00347 3.8e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MCDHIGFA_00348 3.4e-129 S (CBS) domain
MCDHIGFA_00349 1.5e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MCDHIGFA_00350 5.1e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MCDHIGFA_00351 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MCDHIGFA_00352 1.6e-33 yabO J S4 domain protein
MCDHIGFA_00353 6.8e-60 divIC D Septum formation initiator
MCDHIGFA_00354 6.3e-63 yabR J S1 RNA binding domain
MCDHIGFA_00355 2e-241 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MCDHIGFA_00356 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MCDHIGFA_00357 9.7e-166 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MCDHIGFA_00358 5.2e-195 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MCDHIGFA_00359 5.8e-299 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MCDHIGFA_00362 6.9e-216 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MCDHIGFA_00363 2.2e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MCDHIGFA_00364 3.7e-105 engB D Necessary for normal cell division and for the maintenance of normal septation
MCDHIGFA_00365 1.1e-21 yjeM E Amino Acid
MCDHIGFA_00366 1.3e-88 yjeM E Amino acid permease
MCDHIGFA_00367 2.3e-192 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MCDHIGFA_00368 3.9e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
MCDHIGFA_00369 1.1e-247 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MCDHIGFA_00370 6.5e-54 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MCDHIGFA_00371 2.7e-16 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MCDHIGFA_00372 8.9e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MCDHIGFA_00373 9.8e-177 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MCDHIGFA_00374 7e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MCDHIGFA_00375 3.8e-218 aspC 2.6.1.1 E Aminotransferase
MCDHIGFA_00376 1.6e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MCDHIGFA_00377 3.6e-194 pbpX1 V Beta-lactamase
MCDHIGFA_00378 5.4e-300 I Protein of unknown function (DUF2974)
MCDHIGFA_00379 3.6e-39 C FMN_bind
MCDHIGFA_00380 3e-82
MCDHIGFA_00381 1.3e-176 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
MCDHIGFA_00382 6.4e-90 alkD L DNA alkylation repair enzyme
MCDHIGFA_00383 2e-293 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MCDHIGFA_00384 3.7e-128 K UTRA domain
MCDHIGFA_00385 1.6e-55 celA1 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
MCDHIGFA_00386 1.5e-59 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
MCDHIGFA_00387 4.4e-86
MCDHIGFA_00388 2.5e-250 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MCDHIGFA_00389 3.2e-71 S Domain of unknown function (DUF3284)
MCDHIGFA_00390 4.8e-303 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MCDHIGFA_00391 4e-133 gmuR K UTRA
MCDHIGFA_00392 1e-40
MCDHIGFA_00393 1.3e-265 lacE G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MCDHIGFA_00394 6.6e-278 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MCDHIGFA_00395 3.8e-159 ypbG 2.7.1.2 GK ROK family
MCDHIGFA_00396 1.2e-85 C nitroreductase
MCDHIGFA_00397 6e-182 arbY M Glycosyl transferase family 8
MCDHIGFA_00398 4.5e-185 arbY M Glycosyl transferase family 8
MCDHIGFA_00399 5.9e-157 arbx M Glycosyl transferase family 8
MCDHIGFA_00400 1.4e-149 arbV 2.3.1.51 I Acyl-transferase
MCDHIGFA_00402 4.9e-34
MCDHIGFA_00404 4.8e-131 K response regulator
MCDHIGFA_00405 2.2e-305 vicK 2.7.13.3 T Histidine kinase
MCDHIGFA_00406 3.3e-258 yycH S YycH protein
MCDHIGFA_00407 2.9e-148 yycI S YycH protein
MCDHIGFA_00408 4e-53 vicX 3.1.26.11 S domain protein
MCDHIGFA_00409 7.7e-70 vicX 3.1.26.11 S domain protein
MCDHIGFA_00410 3.3e-151 htrA 3.4.21.107 O serine protease
MCDHIGFA_00411 1e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MCDHIGFA_00412 1.6e-33 G Peptidase_C39 like family
MCDHIGFA_00413 6.3e-162 M NlpC/P60 family
MCDHIGFA_00414 5e-91 G Peptidase_C39 like family
MCDHIGFA_00415 2.9e-159 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
MCDHIGFA_00416 9.9e-75 P Cobalt transport protein
MCDHIGFA_00417 4.8e-249 cbiO1 S ABC transporter, ATP-binding protein
MCDHIGFA_00418 2.6e-10 K helix_turn_helix, arabinose operon control protein
MCDHIGFA_00419 1.4e-153 K helix_turn_helix, arabinose operon control protein
MCDHIGFA_00420 1e-159 htpX O Belongs to the peptidase M48B family
MCDHIGFA_00421 3e-96 lemA S LemA family
MCDHIGFA_00422 4e-193 ybiR P Citrate transporter
MCDHIGFA_00423 2.7e-70 S Iron-sulphur cluster biosynthesis
MCDHIGFA_00424 3.2e-309 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
MCDHIGFA_00425 1.2e-17
MCDHIGFA_00426 4e-116
MCDHIGFA_00428 6.8e-216 ydaM M Glycosyl transferase
MCDHIGFA_00429 6.2e-178 G Glycosyl hydrolases family 8
MCDHIGFA_00430 1.4e-121 yfbR S HD containing hydrolase-like enzyme
MCDHIGFA_00431 3.2e-158 L HNH nucleases
MCDHIGFA_00432 1.2e-137 S Protein of unknown function (DUF805)
MCDHIGFA_00433 1.2e-135 glnQ E ABC transporter, ATP-binding protein
MCDHIGFA_00434 1.8e-290 glnP P ABC transporter permease
MCDHIGFA_00435 4.6e-308 oppA E ABC transporter substrate-binding protein
MCDHIGFA_00436 2.5e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MCDHIGFA_00437 0.0 smc D Required for chromosome condensation and partitioning
MCDHIGFA_00438 2.1e-161 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MCDHIGFA_00439 3.8e-289 pipD E Dipeptidase
MCDHIGFA_00440 4.9e-48
MCDHIGFA_00441 2.4e-133 cysA V ABC transporter, ATP-binding protein
MCDHIGFA_00442 0.0 V FtsX-like permease family
MCDHIGFA_00443 1.7e-260 yfnA E amino acid
MCDHIGFA_00444 6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MCDHIGFA_00445 1.7e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MCDHIGFA_00446 1.3e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MCDHIGFA_00447 3.4e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MCDHIGFA_00448 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MCDHIGFA_00449 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MCDHIGFA_00450 8.7e-212 S SLAP domain
MCDHIGFA_00451 4.9e-122 ung2 3.2.2.27 L Uracil-DNA glycosylase
MCDHIGFA_00452 2e-146 E GDSL-like Lipase/Acylhydrolase family
MCDHIGFA_00453 2e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MCDHIGFA_00454 1.4e-38 ynzC S UPF0291 protein
MCDHIGFA_00455 3.3e-30 yneF S Uncharacterised protein family (UPF0154)
MCDHIGFA_00456 0.0 mdlA V ABC transporter
MCDHIGFA_00457 0.0 mdlB V ABC transporter
MCDHIGFA_00458 0.0 pepO 3.4.24.71 O Peptidase family M13
MCDHIGFA_00459 4.4e-85 dps P Belongs to the Dps family
MCDHIGFA_00460 0.0 oppA E ABC transporter substrate-binding protein
MCDHIGFA_00461 2.3e-132 S SLAP domain
MCDHIGFA_00462 9.9e-98 L An automated process has identified a potential problem with this gene model
MCDHIGFA_00463 3.2e-231 K Putative DNA-binding domain
MCDHIGFA_00464 9.3e-35
MCDHIGFA_00465 6.3e-159 S reductase
MCDHIGFA_00466 6.3e-46
MCDHIGFA_00467 1.4e-207 V ABC transporter transmembrane region
MCDHIGFA_00468 8.3e-95 K Helix-turn-helix XRE-family like proteins
MCDHIGFA_00469 5.8e-85 2.3.1.128 K Acetyltransferase (GNAT) domain
MCDHIGFA_00470 1.1e-89 4.2.1.53 S Myosin-crossreactive antigen
MCDHIGFA_00471 4.9e-226 4.2.1.53 S Myosin-crossreactive antigen
MCDHIGFA_00472 2e-91 yxdD K Bacterial regulatory proteins, tetR family
MCDHIGFA_00473 8.5e-260 emrY EGP Major facilitator Superfamily
MCDHIGFA_00478 1.1e-94 MA20_25245 K Acetyltransferase (GNAT) domain
MCDHIGFA_00479 9e-256 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MCDHIGFA_00480 3.2e-200 pbpX V Beta-lactamase
MCDHIGFA_00481 2.8e-244 nhaC C Na H antiporter NhaC
MCDHIGFA_00482 2.4e-147 I transferase activity, transferring acyl groups other than amino-acyl groups
MCDHIGFA_00483 1.3e-56
MCDHIGFA_00484 4.3e-108 ybhL S Belongs to the BI1 family
MCDHIGFA_00485 7.2e-172 yegS 2.7.1.107 G Lipid kinase
MCDHIGFA_00486 4.1e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MCDHIGFA_00487 5.2e-270 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MCDHIGFA_00488 1.5e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MCDHIGFA_00489 5.8e-203 camS S sex pheromone
MCDHIGFA_00490 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MCDHIGFA_00491 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MCDHIGFA_00492 2.5e-86 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
MCDHIGFA_00494 1.4e-83 ydcK S Belongs to the SprT family
MCDHIGFA_00495 9.1e-135 M Glycosyltransferase sugar-binding region containing DXD motif
MCDHIGFA_00496 5.4e-259 epsU S Polysaccharide biosynthesis protein
MCDHIGFA_00497 2.7e-224 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MCDHIGFA_00498 0.0 pacL 3.6.3.8 P P-type ATPase
MCDHIGFA_00499 4e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MCDHIGFA_00500 3.5e-285 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MCDHIGFA_00501 2.6e-205 csaB M Glycosyl transferases group 1
MCDHIGFA_00502 7.3e-135 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MCDHIGFA_00503 5.1e-71 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
MCDHIGFA_00504 1.3e-125 gntR1 K UTRA
MCDHIGFA_00505 1.1e-179
MCDHIGFA_00506 7.1e-300 oppA2 E ABC transporter, substratebinding protein
MCDHIGFA_00509 1.7e-241 npr 1.11.1.1 C NADH oxidase
MCDHIGFA_00510 7.7e-12
MCDHIGFA_00511 1.3e-22 3.6.4.12 S transposase or invertase
MCDHIGFA_00512 2.3e-228 slpX S SLAP domain
MCDHIGFA_00513 4.4e-144 K SIS domain
MCDHIGFA_00514 2.1e-123 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
MCDHIGFA_00515 1.2e-180 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
MCDHIGFA_00516 2e-211 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
MCDHIGFA_00517 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
MCDHIGFA_00519 1.9e-113 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MCDHIGFA_00520 1.7e-114 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
MCDHIGFA_00521 2.6e-89 G Histidine phosphatase superfamily (branch 1)
MCDHIGFA_00522 1.2e-105 G Phosphoglycerate mutase family
MCDHIGFA_00523 2.5e-160 D nuclear chromosome segregation
MCDHIGFA_00524 3.4e-78 M LysM domain protein
MCDHIGFA_00525 1.1e-28 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MCDHIGFA_00526 1.1e-115 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MCDHIGFA_00527 6.2e-12
MCDHIGFA_00528 3.6e-173 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
MCDHIGFA_00529 2.3e-30
MCDHIGFA_00531 1.5e-70 S Iron-sulphur cluster biosynthesis
MCDHIGFA_00532 3.8e-113 yncA 2.3.1.79 S Maltose acetyltransferase
MCDHIGFA_00533 1e-61 psiE S Phosphate-starvation-inducible E
MCDHIGFA_00535 5.7e-141 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
MCDHIGFA_00536 9.7e-59
MCDHIGFA_00537 0.0 lhr L DEAD DEAH box helicase
MCDHIGFA_00538 2e-252 P P-loop Domain of unknown function (DUF2791)
MCDHIGFA_00539 0.0 S TerB-C domain
MCDHIGFA_00540 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
MCDHIGFA_00541 2.1e-126 V ABC-type multidrug transport system, ATPase and permease components
MCDHIGFA_00542 6.2e-83 V ABC-type multidrug transport system, ATPase and permease components
MCDHIGFA_00543 5.9e-10 V ABC-type multidrug transport system, ATPase and permease components
MCDHIGFA_00544 4.9e-133 yheS_2 S ATPases associated with a variety of cellular activities
MCDHIGFA_00546 1.3e-258 glnPH2 P ABC transporter permease
MCDHIGFA_00547 3.1e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MCDHIGFA_00548 5.8e-225 S Cysteine-rich secretory protein family
MCDHIGFA_00549 1.8e-206 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MCDHIGFA_00550 3.6e-113
MCDHIGFA_00551 4.1e-201 yibE S overlaps another CDS with the same product name
MCDHIGFA_00552 3.4e-130 yibF S overlaps another CDS with the same product name
MCDHIGFA_00553 1.2e-146 I alpha/beta hydrolase fold
MCDHIGFA_00554 0.0 G Belongs to the glycosyl hydrolase 31 family
MCDHIGFA_00555 3.5e-216 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MCDHIGFA_00556 2.2e-273 S Archaea bacterial proteins of unknown function
MCDHIGFA_00557 1.6e-07
MCDHIGFA_00558 6.3e-23 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
MCDHIGFA_00559 3.6e-90 ntd 2.4.2.6 F Nucleoside
MCDHIGFA_00560 7e-89 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MCDHIGFA_00561 1.7e-148 ptp3 3.1.3.48 T Tyrosine phosphatase family
MCDHIGFA_00562 5.2e-84 uspA T universal stress protein
MCDHIGFA_00563 1.2e-150 phnD P Phosphonate ABC transporter
MCDHIGFA_00564 4.1e-136 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MCDHIGFA_00565 2.3e-118 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
MCDHIGFA_00566 2.2e-148 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
MCDHIGFA_00567 3.3e-106 tag 3.2.2.20 L glycosylase
MCDHIGFA_00568 1.5e-83
MCDHIGFA_00569 3.4e-274 S Calcineurin-like phosphoesterase
MCDHIGFA_00570 0.0 asnB 6.3.5.4 E Asparagine synthase
MCDHIGFA_00571 5.6e-255 yxbA 6.3.1.12 S ATP-grasp enzyme
MCDHIGFA_00572 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
MCDHIGFA_00573 8.7e-141 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MCDHIGFA_00574 2.8e-103 S Iron-sulfur cluster assembly protein
MCDHIGFA_00575 1.5e-230 XK27_04775 S PAS domain
MCDHIGFA_00576 1e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
MCDHIGFA_00577 5.9e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MCDHIGFA_00578 7.8e-151 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MCDHIGFA_00579 2.6e-138 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MCDHIGFA_00580 4.6e-157 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MCDHIGFA_00581 1.4e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MCDHIGFA_00582 1.4e-60 rplQ J Ribosomal protein L17
MCDHIGFA_00583 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MCDHIGFA_00584 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MCDHIGFA_00585 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MCDHIGFA_00586 7.8e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MCDHIGFA_00587 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MCDHIGFA_00588 3.5e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MCDHIGFA_00589 1.4e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MCDHIGFA_00590 2.6e-71 rplO J Binds to the 23S rRNA
MCDHIGFA_00591 2.3e-24 rpmD J Ribosomal protein L30
MCDHIGFA_00592 9.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MCDHIGFA_00593 3.6e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MCDHIGFA_00594 3.3e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MCDHIGFA_00595 3.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MCDHIGFA_00596 6.8e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MCDHIGFA_00597 5.5e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MCDHIGFA_00598 3.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MCDHIGFA_00599 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MCDHIGFA_00600 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MCDHIGFA_00601 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
MCDHIGFA_00602 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MCDHIGFA_00603 2.7e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MCDHIGFA_00604 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MCDHIGFA_00605 1.1e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MCDHIGFA_00606 7.3e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MCDHIGFA_00607 3.1e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MCDHIGFA_00608 2.1e-106 rplD J Forms part of the polypeptide exit tunnel
MCDHIGFA_00609 9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MCDHIGFA_00610 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
MCDHIGFA_00611 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MCDHIGFA_00612 2.7e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MCDHIGFA_00613 7.8e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MCDHIGFA_00614 3.6e-120 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
MCDHIGFA_00615 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MCDHIGFA_00616 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MCDHIGFA_00617 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MCDHIGFA_00618 1.1e-80 yebR 1.8.4.14 T GAF domain-containing protein
MCDHIGFA_00621 3.5e-108 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MCDHIGFA_00622 1.4e-115 S Peptidase family M23
MCDHIGFA_00623 1.7e-28
MCDHIGFA_00624 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
MCDHIGFA_00625 3.9e-34 copZ C Heavy-metal-associated domain
MCDHIGFA_00626 2.9e-96 dps P Belongs to the Dps family
MCDHIGFA_00627 4e-113 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
MCDHIGFA_00628 1.1e-93 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MCDHIGFA_00629 4.1e-259 3.4.24.25, 3.4.24.26 UW LPXTG-motif cell wall anchor domain protein
MCDHIGFA_00630 1.2e-122 UW LPXTG-motif cell wall anchor domain protein
MCDHIGFA_00631 7.7e-22
MCDHIGFA_00632 1.8e-62 L PFAM IS66 Orf2 family protein
MCDHIGFA_00633 5.2e-221 L Transposase IS66 family
MCDHIGFA_00635 5.3e-46
MCDHIGFA_00636 0.0 cas3 L CRISPR-associated helicase cas3
MCDHIGFA_00637 0.0 casA L the current gene model (or a revised gene model) may contain a frame shift
MCDHIGFA_00638 8.8e-110 casB S CRISPR-associated protein Cse2 (CRISPR_cse2)
MCDHIGFA_00639 1.9e-198 casC L CT1975-like protein
MCDHIGFA_00640 2.8e-131 casD S CRISPR-associated protein (Cas_Cas5)
MCDHIGFA_00641 6.4e-122 casE S CRISPR_assoc
MCDHIGFA_00642 3.9e-173 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MCDHIGFA_00643 4.4e-166 cas2 2.7.7.7 L CRISPR-associated protein (Cas_Cas2CT1978)
MCDHIGFA_00644 3.6e-154 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MCDHIGFA_00645 2.3e-285 oppA E ABC transporter substrate-binding protein
MCDHIGFA_00646 6.2e-131 oppC P Binding-protein-dependent transport system inner membrane component
MCDHIGFA_00647 5.7e-172 oppB P ABC transporter permease
MCDHIGFA_00648 1.5e-170 oppF P Belongs to the ABC transporter superfamily
MCDHIGFA_00649 3.1e-192 oppD P Belongs to the ABC transporter superfamily
MCDHIGFA_00650 1.8e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MCDHIGFA_00651 1.3e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MCDHIGFA_00652 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MCDHIGFA_00653 2e-305 yloV S DAK2 domain fusion protein YloV
MCDHIGFA_00654 4e-57 asp S Asp23 family, cell envelope-related function
MCDHIGFA_00655 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MCDHIGFA_00656 4.8e-31
MCDHIGFA_00657 1.4e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
MCDHIGFA_00658 1.7e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MCDHIGFA_00659 1.8e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MCDHIGFA_00660 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
MCDHIGFA_00661 1.1e-138 stp 3.1.3.16 T phosphatase
MCDHIGFA_00662 1.6e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MCDHIGFA_00663 2.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MCDHIGFA_00664 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MCDHIGFA_00665 1.1e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MCDHIGFA_00666 2.1e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
MCDHIGFA_00667 1.1e-77 6.3.3.2 S ASCH
MCDHIGFA_00668 1e-293 recN L May be involved in recombinational repair of damaged DNA
MCDHIGFA_00669 2.2e-148 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MCDHIGFA_00670 9.2e-153 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MCDHIGFA_00671 1.1e-34 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MCDHIGFA_00672 3.8e-185 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MCDHIGFA_00673 5e-143 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MCDHIGFA_00674 6.2e-64 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MCDHIGFA_00675 1.3e-70 yqhY S Asp23 family, cell envelope-related function
MCDHIGFA_00676 4.9e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MCDHIGFA_00677 6.6e-196 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MCDHIGFA_00678 9.7e-59 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MCDHIGFA_00679 3.5e-54 trxA O Belongs to the thioredoxin family
MCDHIGFA_00680 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MCDHIGFA_00681 1.1e-50 yrzB S Belongs to the UPF0473 family
MCDHIGFA_00682 6.1e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MCDHIGFA_00683 2e-42 yrzL S Belongs to the UPF0297 family
MCDHIGFA_00684 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MCDHIGFA_00685 1.4e-227 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MCDHIGFA_00686 5.2e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
MCDHIGFA_00687 5.9e-216 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MCDHIGFA_00688 5.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MCDHIGFA_00689 9.6e-41 yajC U Preprotein translocase
MCDHIGFA_00690 6.7e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MCDHIGFA_00691 4.5e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MCDHIGFA_00692 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MCDHIGFA_00693 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MCDHIGFA_00694 2.6e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MCDHIGFA_00695 1.4e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MCDHIGFA_00696 3.5e-75
MCDHIGFA_00697 2.3e-181 M CHAP domain
MCDHIGFA_00698 0.0 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
MCDHIGFA_00699 1.2e-293 scrB 3.2.1.26 GH32 G invertase
MCDHIGFA_00700 8e-169 scrR K helix_turn _helix lactose operon repressor
MCDHIGFA_00701 1.2e-141 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MCDHIGFA_00702 1.9e-116 V ABC transporter transmembrane region
MCDHIGFA_00705 2.2e-162
MCDHIGFA_00707 9.3e-38
MCDHIGFA_00708 3.2e-159 EG EamA-like transporter family
MCDHIGFA_00709 1.6e-166 EG EamA-like transporter family
MCDHIGFA_00710 7.3e-83 yicL EG EamA-like transporter family
MCDHIGFA_00711 2.5e-107
MCDHIGFA_00712 1.1e-110
MCDHIGFA_00713 1e-68 XK27_05540 S DUF218 domain
MCDHIGFA_00714 5.7e-95 XK27_05540 S DUF218 domain
MCDHIGFA_00715 1.1e-264 yheS_2 S ATPases associated with a variety of cellular activities
MCDHIGFA_00716 7.7e-88
MCDHIGFA_00717 3.9e-57
MCDHIGFA_00718 1.2e-28 S Protein conserved in bacteria
MCDHIGFA_00719 3.1e-245 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MCDHIGFA_00720 1.9e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MCDHIGFA_00721 7e-189 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MCDHIGFA_00724 3.9e-206 4.2.1.126 S Bacterial protein of unknown function (DUF871)
MCDHIGFA_00725 1.3e-190 asnA 6.3.1.1 F aspartate--ammonia ligase
MCDHIGFA_00726 1e-230 steT_1 E amino acid
MCDHIGFA_00727 5.7e-140 puuD S peptidase C26
MCDHIGFA_00728 5e-07 yokH G SMI1 / KNR4 family
MCDHIGFA_00729 1.1e-97 V HNH endonuclease
MCDHIGFA_00730 2.5e-26 V HNH endonuclease
MCDHIGFA_00731 4.9e-135 S PFAM Archaeal ATPase
MCDHIGFA_00732 2.4e-248 yifK E Amino acid permease
MCDHIGFA_00733 8.2e-233 cycA E Amino acid permease
MCDHIGFA_00734 1.7e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MCDHIGFA_00735 0.0 clpE O AAA domain (Cdc48 subfamily)
MCDHIGFA_00736 4.4e-166 S Alpha/beta hydrolase of unknown function (DUF915)
MCDHIGFA_00737 3.9e-99 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MCDHIGFA_00738 2e-39 S Transglycosylase associated protein
MCDHIGFA_00739 1.5e-211 M Glycosyl hydrolases family 25
MCDHIGFA_00740 8e-111 XK27_00160 S Domain of unknown function (DUF5052)
MCDHIGFA_00741 1.6e-66
MCDHIGFA_00742 1.8e-203 xerS L Belongs to the 'phage' integrase family
MCDHIGFA_00743 1.7e-288 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MCDHIGFA_00744 2.3e-159 degV S EDD domain protein, DegV family
MCDHIGFA_00745 1.1e-66
MCDHIGFA_00746 0.0 FbpA K Fibronectin-binding protein
MCDHIGFA_00747 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
MCDHIGFA_00748 4.6e-199 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MCDHIGFA_00749 4.3e-169 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MCDHIGFA_00750 8e-79 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MCDHIGFA_00751 3.5e-281 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
MCDHIGFA_00752 5.5e-53
MCDHIGFA_00753 8.8e-106 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
MCDHIGFA_00755 4.8e-73 S Sel1-like repeats.
MCDHIGFA_00756 1.6e-97 3.1.4.37 S AAA domain
MCDHIGFA_00757 8.6e-182
MCDHIGFA_00758 1.2e-32
MCDHIGFA_00759 3.2e-77 S HIRAN
MCDHIGFA_00760 7.9e-68 S Sel1-like repeats.
MCDHIGFA_00761 2.4e-90
MCDHIGFA_00762 3.5e-09 S Domain of unknown function (DUF3841)
MCDHIGFA_00763 4.2e-151 S Domain of unknown function (DUF3883)
MCDHIGFA_00764 1.5e-113 mrr L restriction endonuclease
MCDHIGFA_00765 3.8e-176 citR K Putative sugar-binding domain
MCDHIGFA_00766 3.8e-51
MCDHIGFA_00767 5.5e-09
MCDHIGFA_00768 2.9e-66 S Domain of unknown function DUF1828
MCDHIGFA_00769 5.6e-95 S UPF0397 protein
MCDHIGFA_00770 0.0 ykoD P ABC transporter, ATP-binding protein
MCDHIGFA_00771 3e-145 cbiQ P cobalt transport
MCDHIGFA_00772 1.8e-22
MCDHIGFA_00773 9.3e-72 yeaL S Protein of unknown function (DUF441)
MCDHIGFA_00774 1.9e-289 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
MCDHIGFA_00775 8.2e-168 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
MCDHIGFA_00776 1.2e-43 citD C Covalent carrier of the coenzyme of citrate lyase
MCDHIGFA_00777 1.1e-195 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MCDHIGFA_00778 6.5e-122 ydjP I Alpha/beta hydrolase family
MCDHIGFA_00779 4.7e-274 P Sodium:sulfate symporter transmembrane region
MCDHIGFA_00780 1.3e-133 hxlA 6.2.1.3 H Aldolase/RraA
MCDHIGFA_00781 6.1e-257 pepC 3.4.22.40 E Peptidase C1-like family
MCDHIGFA_00782 3.1e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MCDHIGFA_00783 6.6e-262 frdC 1.3.5.4 C FAD binding domain
MCDHIGFA_00784 7.6e-266 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MCDHIGFA_00785 2e-73 metI P ABC transporter permease
MCDHIGFA_00786 3e-190 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MCDHIGFA_00787 2.9e-159 metQ2 P Belongs to the nlpA lipoprotein family
MCDHIGFA_00788 5.8e-177 F DNA/RNA non-specific endonuclease
MCDHIGFA_00789 0.0 aha1 P E1-E2 ATPase
MCDHIGFA_00790 1.5e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MCDHIGFA_00791 8.2e-179 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MCDHIGFA_00792 7.8e-277 M Peptidase family M1 domain
MCDHIGFA_00793 7.4e-175 S SLAP domain
MCDHIGFA_00794 9.3e-237 mepA V MATE efflux family protein
MCDHIGFA_00795 2.3e-248 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MCDHIGFA_00796 1.7e-122 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MCDHIGFA_00797 2.8e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MCDHIGFA_00798 3.8e-13 S Protein of unknown function (DUF805)
MCDHIGFA_00799 3.3e-126 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MCDHIGFA_00800 2.2e-221 ecsB U ABC transporter
MCDHIGFA_00801 2e-135 ecsA V ABC transporter, ATP-binding protein
MCDHIGFA_00802 2.8e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
MCDHIGFA_00803 3.9e-25
MCDHIGFA_00804 1.5e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MCDHIGFA_00805 1.5e-72 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
MCDHIGFA_00806 3.6e-266
MCDHIGFA_00807 1.7e-187 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
MCDHIGFA_00808 0.0 L AAA domain
MCDHIGFA_00809 2.8e-232 yhaO L Ser Thr phosphatase family protein
MCDHIGFA_00810 7.2e-56 yheA S Belongs to the UPF0342 family
MCDHIGFA_00811 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MCDHIGFA_00812 6.5e-151 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MCDHIGFA_00813 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
MCDHIGFA_00814 3.6e-111 G Phosphoglycerate mutase family
MCDHIGFA_00815 1.2e-140 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MCDHIGFA_00816 1.2e-257 L Putative transposase DNA-binding domain
MCDHIGFA_00817 4.6e-114 L Resolvase, N-terminal
MCDHIGFA_00818 7.3e-164 S Protein of unknown function (DUF2974)
MCDHIGFA_00819 4.7e-109 glnP P ABC transporter permease
MCDHIGFA_00820 9.7e-91 gluC P ABC transporter permease
MCDHIGFA_00821 1.5e-149 glnH ET ABC transporter substrate-binding protein
MCDHIGFA_00822 1.9e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MCDHIGFA_00823 3.3e-92 udk 2.7.1.48 F Zeta toxin
MCDHIGFA_00824 3e-254 G MFS/sugar transport protein
MCDHIGFA_00825 3.8e-102 S ABC-type cobalt transport system, permease component
MCDHIGFA_00826 0.0 V ABC transporter transmembrane region
MCDHIGFA_00827 1.7e-310 XK27_09600 V ABC transporter, ATP-binding protein
MCDHIGFA_00828 1.4e-80 K Transcriptional regulator, MarR family
MCDHIGFA_00829 3.8e-148 glnH ET ABC transporter
MCDHIGFA_00830 4.9e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
MCDHIGFA_00831 3.9e-243 steT E amino acid
MCDHIGFA_00832 8e-241 steT E amino acid
MCDHIGFA_00833 6.1e-151
MCDHIGFA_00834 5e-173 S Aldo keto reductase
MCDHIGFA_00835 2.7e-310 ybiT S ABC transporter, ATP-binding protein
MCDHIGFA_00836 2.3e-209 pepA E M42 glutamyl aminopeptidase
MCDHIGFA_00837 3.8e-102
MCDHIGFA_00838 6.9e-136
MCDHIGFA_00839 1.6e-13 mdtG EGP Major facilitator Superfamily
MCDHIGFA_00842 2.4e-215 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MCDHIGFA_00843 7.2e-179 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
MCDHIGFA_00844 0.0 yjbQ P TrkA C-terminal domain protein
MCDHIGFA_00845 1.7e-106 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MCDHIGFA_00846 1e-160 S Oxidoreductase family, NAD-binding Rossmann fold
MCDHIGFA_00847 4.1e-131
MCDHIGFA_00848 3.9e-115
MCDHIGFA_00849 8.4e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MCDHIGFA_00850 4.9e-99 G Aldose 1-epimerase
MCDHIGFA_00851 1.8e-201 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MCDHIGFA_00852 5.6e-112 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MCDHIGFA_00853 0.0 XK27_08315 M Sulfatase
MCDHIGFA_00854 2e-266 S Fibronectin type III domain
MCDHIGFA_00855 3.7e-243 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MCDHIGFA_00856 1.2e-53
MCDHIGFA_00858 1.4e-258 pepC 3.4.22.40 E aminopeptidase
MCDHIGFA_00859 2.6e-123 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
MCDHIGFA_00860 1.7e-301 oppA E ABC transporter, substratebinding protein
MCDHIGFA_00861 5e-309 oppA E ABC transporter, substratebinding protein
MCDHIGFA_00862 1.7e-210 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MCDHIGFA_00863 1.1e-146 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
MCDHIGFA_00864 8e-188 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
MCDHIGFA_00865 6.1e-199 oppD P Belongs to the ABC transporter superfamily
MCDHIGFA_00866 1.9e-175 oppF P Belongs to the ABC transporter superfamily
MCDHIGFA_00867 3e-256 pepC 3.4.22.40 E aminopeptidase
MCDHIGFA_00868 3.5e-73 hsp O Belongs to the small heat shock protein (HSP20) family
MCDHIGFA_00869 7.5e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MCDHIGFA_00870 1.2e-112
MCDHIGFA_00872 4.6e-111 E Belongs to the SOS response-associated peptidase family
MCDHIGFA_00873 4.8e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
MCDHIGFA_00874 1.8e-89 comEB 3.5.4.12 F MafB19-like deaminase
MCDHIGFA_00875 2e-103 S TPM domain
MCDHIGFA_00876 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
MCDHIGFA_00877 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MCDHIGFA_00878 1.8e-147 tatD L hydrolase, TatD family
MCDHIGFA_00879 1e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MCDHIGFA_00880 3.9e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MCDHIGFA_00881 1.2e-39 veg S Biofilm formation stimulator VEG
MCDHIGFA_00882 2.7e-135 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
MCDHIGFA_00883 2.2e-172 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MCDHIGFA_00884 5.3e-80
MCDHIGFA_00885 0.0 S SLAP domain
MCDHIGFA_00886 2.3e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MCDHIGFA_00887 6.1e-171 2.7.1.2 GK ROK family
MCDHIGFA_00888 6.5e-44
MCDHIGFA_00889 1.6e-268 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
MCDHIGFA_00890 2.6e-68 S Domain of unknown function (DUF1934)
MCDHIGFA_00891 1.4e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MCDHIGFA_00892 6.7e-311 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MCDHIGFA_00893 2.8e-246 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MCDHIGFA_00894 3.6e-80 K acetyltransferase
MCDHIGFA_00895 1.3e-47 adk 2.7.4.3 F AAA domain
MCDHIGFA_00896 6.5e-281 pipD E Dipeptidase
MCDHIGFA_00897 6e-154 msmR K AraC-like ligand binding domain
MCDHIGFA_00898 8.9e-229 pbuX F xanthine permease
MCDHIGFA_00899 1.2e-103 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MCDHIGFA_00900 1e-133 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MCDHIGFA_00901 8.3e-122 S CAAX protease self-immunity
MCDHIGFA_00902 1.2e-53
MCDHIGFA_00903 4.7e-157 mutR K Helix-turn-helix XRE-family like proteins
MCDHIGFA_00904 3.9e-73 S Putative adhesin
MCDHIGFA_00905 5.5e-281 V ABC transporter transmembrane region
MCDHIGFA_00906 1.7e-205 napA P Sodium/hydrogen exchanger family
MCDHIGFA_00907 0.0 cadA P P-type ATPase
MCDHIGFA_00908 1.9e-80 ykuL S (CBS) domain
MCDHIGFA_00909 1.5e-216 ywhK S Membrane
MCDHIGFA_00910 4.7e-48
MCDHIGFA_00911 5.2e-19 S D-Ala-teichoic acid biosynthesis protein
MCDHIGFA_00912 2.2e-287 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MCDHIGFA_00913 4.6e-238 dltB M MBOAT, membrane-bound O-acyltransferase family
MCDHIGFA_00914 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MCDHIGFA_00915 3.3e-247 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MCDHIGFA_00916 7.6e-177 pbpX2 V Beta-lactamase
MCDHIGFA_00917 1.3e-133 S Protein of unknown function (DUF975)
MCDHIGFA_00918 2.7e-137 lysA2 M Glycosyl hydrolases family 25
MCDHIGFA_00919 2.8e-288 ytgP S Polysaccharide biosynthesis protein
MCDHIGFA_00920 1.9e-36
MCDHIGFA_00921 0.0 XK27_06780 V ABC transporter permease
MCDHIGFA_00922 1.2e-123 XK27_06785 V ABC transporter, ATP-binding protein
MCDHIGFA_00923 6.6e-43 2.7.7.73, 2.7.7.80 H ThiF family
MCDHIGFA_00924 4.3e-38 2.7.7.73, 2.7.7.80 H ThiF family
MCDHIGFA_00925 2.1e-66 K Helix-turn-helix XRE-family like proteins
MCDHIGFA_00926 3.8e-111 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MCDHIGFA_00927 0.0 uup S ABC transporter, ATP-binding protein
MCDHIGFA_00928 2.9e-178 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
MCDHIGFA_00929 1.3e-165 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MCDHIGFA_00930 4.5e-95 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MCDHIGFA_00931 1.3e-108 dnaX 2.4.99.16, 2.7.7.7 GH13 M domain protein
MCDHIGFA_00933 1.2e-113 K UTRA
MCDHIGFA_00934 3.8e-163 S Oxidoreductase family, NAD-binding Rossmann fold
MCDHIGFA_00935 6e-126 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MCDHIGFA_00936 3.8e-193 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MCDHIGFA_00937 4.8e-96 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
MCDHIGFA_00938 4e-133 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
MCDHIGFA_00939 1.5e-86 S ECF transporter, substrate-specific component
MCDHIGFA_00940 6.4e-131 fat 3.1.2.21 I Acyl-ACP thioesterase
MCDHIGFA_00941 1.5e-155 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MCDHIGFA_00942 1.8e-59 yabA L Involved in initiation control of chromosome replication
MCDHIGFA_00943 1.3e-154 holB 2.7.7.7 L DNA polymerase III
MCDHIGFA_00944 8.9e-53 yaaQ S Cyclic-di-AMP receptor
MCDHIGFA_00945 1.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MCDHIGFA_00946 1.5e-177 I Carboxylesterase family
MCDHIGFA_00947 1.5e-64 arsC 1.20.4.1 P Belongs to the ArsC family
MCDHIGFA_00948 5.2e-279 V ABC-type multidrug transport system, ATPase and permease components
MCDHIGFA_00949 6.5e-207 V ABC-type multidrug transport system, ATPase and permease components
MCDHIGFA_00950 2.8e-66 V ABC-type multidrug transport system, ATPase and permease components
MCDHIGFA_00951 4.6e-154 S haloacid dehalogenase-like hydrolase
MCDHIGFA_00952 2.6e-52
MCDHIGFA_00953 1.9e-37
MCDHIGFA_00954 2e-42 S Alpha beta hydrolase
MCDHIGFA_00955 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MCDHIGFA_00956 8.1e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MCDHIGFA_00957 7.1e-46
MCDHIGFA_00958 6.1e-149 glcU U sugar transport
MCDHIGFA_00959 9.9e-251 lctP C L-lactate permease
MCDHIGFA_00960 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MCDHIGFA_00961 6.4e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MCDHIGFA_00962 8.8e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MCDHIGFA_00963 5.5e-183 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MCDHIGFA_00964 3.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MCDHIGFA_00965 1.4e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MCDHIGFA_00966 1.6e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MCDHIGFA_00967 1.9e-118 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MCDHIGFA_00968 1.6e-101 GM NmrA-like family
MCDHIGFA_00969 8.2e-276 pipD E Dipeptidase
MCDHIGFA_00970 1.4e-156 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
MCDHIGFA_00971 2e-155 metC1 4.4.1.8 E cystathionine
MCDHIGFA_00972 2.6e-99 metQ1 P Belongs to the nlpA lipoprotein family
MCDHIGFA_00973 1.5e-102 devA 3.6.3.25 V ABC transporter, ATP-binding protein
MCDHIGFA_00974 4.3e-176 hrtB V ABC transporter permease
MCDHIGFA_00975 3.1e-95 ygfC K Bacterial regulatory proteins, tetR family
MCDHIGFA_00976 5.5e-112 G phosphoglycerate mutase
MCDHIGFA_00977 4.9e-142 aroD S Alpha/beta hydrolase family
MCDHIGFA_00978 2.2e-142 S Belongs to the UPF0246 family
MCDHIGFA_00979 9e-121
MCDHIGFA_00980 2.5e-157 2.7.7.12 C Domain of unknown function (DUF4931)
MCDHIGFA_00981 1.5e-190 S Putative peptidoglycan binding domain
MCDHIGFA_00982 4e-16
MCDHIGFA_00983 7.9e-92 liaI S membrane
MCDHIGFA_00984 1.7e-70 XK27_02470 K LytTr DNA-binding domain
MCDHIGFA_00985 1.5e-248 dtpT U amino acid peptide transporter
MCDHIGFA_00986 0.0 pepN 3.4.11.2 E aminopeptidase
MCDHIGFA_00987 2.8e-47 lysM M LysM domain
MCDHIGFA_00988 5.1e-176
MCDHIGFA_00989 1.3e-211 mdtG EGP Major facilitator Superfamily
MCDHIGFA_00990 4.9e-90 ymdB S Macro domain protein
MCDHIGFA_00992 5.2e-09
MCDHIGFA_00994 2e-181 E Sodium:solute symporter family
MCDHIGFA_00995 5.1e-152 4.3.3.7 EM Dihydrodipicolinate synthetase family
MCDHIGFA_00996 1.2e-76 K Transcriptional
MCDHIGFA_00997 2.8e-62 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MCDHIGFA_00998 9.7e-83 S An automated process has identified a potential problem with this gene model
MCDHIGFA_00999 3.3e-136 S Protein of unknown function (DUF3100)
MCDHIGFA_01000 5.9e-44 3.5.1.47 S Peptidase dimerisation domain
MCDHIGFA_01001 1.3e-138 3.5.1.47 S Peptidase dimerisation domain
MCDHIGFA_01002 1.8e-231 Q Imidazolonepropionase and related amidohydrolases
MCDHIGFA_01003 0.0 oppA E ABC transporter
MCDHIGFA_01004 1.8e-150 S Sucrose-6F-phosphate phosphohydrolase
MCDHIGFA_01005 0.0 mco Q Multicopper oxidase
MCDHIGFA_01006 5.7e-25
MCDHIGFA_01007 1.6e-157 metQ1 P Belongs to the nlpA lipoprotein family
MCDHIGFA_01008 4.3e-169 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
MCDHIGFA_01009 4.9e-63 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MCDHIGFA_01010 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MCDHIGFA_01011 2.7e-199 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MCDHIGFA_01012 2.9e-162 cjaA ET ABC transporter substrate-binding protein
MCDHIGFA_01013 3.9e-114 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MCDHIGFA_01014 2.8e-117 P ABC transporter permease
MCDHIGFA_01015 5.1e-111 papP P ABC transporter, permease protein
MCDHIGFA_01016 5.4e-140 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
MCDHIGFA_01017 1.3e-67
MCDHIGFA_01018 4.6e-60
MCDHIGFA_01019 1.2e-216 rodA D Belongs to the SEDS family
MCDHIGFA_01020 1.5e-33 S Protein of unknown function (DUF2969)
MCDHIGFA_01021 2e-51 yidD S Could be involved in insertion of integral membrane proteins into the membrane
MCDHIGFA_01022 2.5e-178 mbl D Cell shape determining protein MreB Mrl
MCDHIGFA_01023 6.1e-18 ywzB S Protein of unknown function (DUF1146)
MCDHIGFA_01024 7.6e-71 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MCDHIGFA_01025 8.1e-255 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MCDHIGFA_01026 1.7e-168 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MCDHIGFA_01027 5.3e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MCDHIGFA_01028 3.7e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MCDHIGFA_01029 6.6e-50 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MCDHIGFA_01030 1.1e-28 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MCDHIGFA_01031 5.1e-125 atpB C it plays a direct role in the translocation of protons across the membrane
MCDHIGFA_01032 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MCDHIGFA_01033 1.4e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MCDHIGFA_01034 1.1e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MCDHIGFA_01035 3.1e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MCDHIGFA_01036 1.3e-113 tdk 2.7.1.21 F thymidine kinase
MCDHIGFA_01037 1.7e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
MCDHIGFA_01040 1e-195 ampC V Beta-lactamase
MCDHIGFA_01041 9.9e-218 EGP Major facilitator Superfamily
MCDHIGFA_01042 4.6e-260 pgi 5.3.1.9 G Belongs to the GPI family
MCDHIGFA_01043 3.6e-63 yodB K Transcriptional regulator, HxlR family
MCDHIGFA_01044 2.3e-139 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MCDHIGFA_01045 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MCDHIGFA_01046 7.6e-164 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MCDHIGFA_01047 1.1e-86 S Aminoacyl-tRNA editing domain
MCDHIGFA_01048 4.7e-224 S SLAP domain
MCDHIGFA_01049 1.8e-50 S CAAX protease self-immunity
MCDHIGFA_01050 4.1e-276 arlS 2.7.13.3 T Histidine kinase
MCDHIGFA_01051 4.6e-126 K response regulator
MCDHIGFA_01052 5.5e-98 yceD S Uncharacterized ACR, COG1399
MCDHIGFA_01053 2.2e-210 ylbM S Belongs to the UPF0348 family
MCDHIGFA_01054 5.3e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MCDHIGFA_01055 2.5e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
MCDHIGFA_01056 1.2e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MCDHIGFA_01057 9.8e-200 yqeH S Ribosome biogenesis GTPase YqeH
MCDHIGFA_01058 2.9e-85 yqeG S HAD phosphatase, family IIIA
MCDHIGFA_01059 3.6e-153 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MCDHIGFA_01060 3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MCDHIGFA_01061 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MCDHIGFA_01062 1.1e-72 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MCDHIGFA_01063 1.3e-49 yyaR K Acetyltransferase (GNAT) domain
MCDHIGFA_01064 2e-106 S domain protein
MCDHIGFA_01065 9.2e-143 V ABC transporter
MCDHIGFA_01066 3.8e-75 S Protein of unknown function (DUF3021)
MCDHIGFA_01067 7.8e-76 K LytTr DNA-binding domain
MCDHIGFA_01068 3.5e-91
MCDHIGFA_01069 2.3e-156 yvgN C Aldo keto reductase
MCDHIGFA_01070 0.0 tetP J elongation factor G
MCDHIGFA_01071 8.7e-145 3.1.3.102, 3.1.3.104 S haloacid dehalogenase-like hydrolase
MCDHIGFA_01072 8.9e-51
MCDHIGFA_01074 2.9e-133 EGP Major facilitator Superfamily
MCDHIGFA_01075 4e-192 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MCDHIGFA_01078 6.9e-158 xth 3.1.11.2 L exodeoxyribonuclease III
MCDHIGFA_01079 1.3e-273 E amino acid
MCDHIGFA_01080 0.0 L Helicase C-terminal domain protein
MCDHIGFA_01081 6.2e-205 pbpX1 V Beta-lactamase
MCDHIGFA_01082 4.6e-227 N Uncharacterized conserved protein (DUF2075)
MCDHIGFA_01083 1.2e-70 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
MCDHIGFA_01084 0.0 O Belongs to the peptidase S8 family
MCDHIGFA_01085 1.3e-174 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
MCDHIGFA_01086 1.5e-93 dhaL 2.7.1.121 S Dak2
MCDHIGFA_01087 1.1e-54 dhaM 2.7.1.121 S PTS system fructose IIA component
MCDHIGFA_01088 6.9e-122 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MCDHIGFA_01089 5.9e-188 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MCDHIGFA_01090 2.3e-144 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
MCDHIGFA_01091 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
MCDHIGFA_01092 1.2e-164 lacR K Transcriptional regulator
MCDHIGFA_01093 0.0 lacS G Transporter
MCDHIGFA_01094 0.0 lacZ 3.2.1.23 G -beta-galactosidase
MCDHIGFA_01095 3.1e-220 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MCDHIGFA_01096 4.4e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MCDHIGFA_01097 6.1e-109 drgA C nitroreductase
MCDHIGFA_01098 1.3e-43 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
MCDHIGFA_01099 2.2e-207 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
MCDHIGFA_01100 1.2e-220 lacE-1 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
MCDHIGFA_01101 1.4e-79 mlc GK ROK family
MCDHIGFA_01102 3.8e-163 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MCDHIGFA_01103 6.7e-241 S Domain of unknown function (DUF4838)
MCDHIGFA_01104 1.4e-112 S SLAP domain
MCDHIGFA_01105 3.8e-89
MCDHIGFA_01106 1.5e-08 isdH M Iron Transport-associated domain
MCDHIGFA_01107 5.7e-124 M Iron Transport-associated domain
MCDHIGFA_01108 1.5e-158 isdE P Periplasmic binding protein
MCDHIGFA_01109 1.1e-148 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MCDHIGFA_01110 8.8e-139 fhuC 3.6.3.34 HP abc transporter atp-binding protein
MCDHIGFA_01111 6.7e-44 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MCDHIGFA_01112 2.6e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
MCDHIGFA_01113 2.4e-37 S RelB antitoxin
MCDHIGFA_01114 5.2e-170 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
MCDHIGFA_01115 2.7e-166 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
MCDHIGFA_01116 1.4e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MCDHIGFA_01117 5.7e-69 rplI J Binds to the 23S rRNA
MCDHIGFA_01118 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MCDHIGFA_01119 1.8e-201 S SLAP domain
MCDHIGFA_01120 1.9e-170 S Bacteriocin helveticin-J
MCDHIGFA_01121 3.2e-42
MCDHIGFA_01122 5.1e-41 ps115 K Helix-turn-helix XRE-family like proteins
MCDHIGFA_01123 2.3e-89 E Zn peptidase
MCDHIGFA_01124 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MCDHIGFA_01125 4.5e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MCDHIGFA_01126 9.4e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
MCDHIGFA_01127 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MCDHIGFA_01128 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MCDHIGFA_01129 6.2e-210 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MCDHIGFA_01130 2.6e-35 yaaA S S4 domain protein YaaA
MCDHIGFA_01131 1.2e-184 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MCDHIGFA_01132 5.5e-245 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MCDHIGFA_01133 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
MCDHIGFA_01134 2.7e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MCDHIGFA_01135 8.4e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MCDHIGFA_01136 1.8e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MCDHIGFA_01137 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MCDHIGFA_01138 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MCDHIGFA_01139 1.1e-93
MCDHIGFA_01140 6.2e-276 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MCDHIGFA_01141 3.7e-285 clcA P chloride
MCDHIGFA_01142 5.4e-137 S SLAP domain
MCDHIGFA_01143 2.5e-211
MCDHIGFA_01144 1.2e-18
MCDHIGFA_01145 9.1e-248 EGP Sugar (and other) transporter
MCDHIGFA_01146 1.2e-105
MCDHIGFA_01147 8.2e-114 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
MCDHIGFA_01148 0.0 copA 3.6.3.54 P P-type ATPase
MCDHIGFA_01149 3.1e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MCDHIGFA_01150 4e-59 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MCDHIGFA_01151 5.1e-75 atkY K Penicillinase repressor
MCDHIGFA_01152 1e-27
MCDHIGFA_01153 1.2e-225 pbuG S permease
MCDHIGFA_01154 3.9e-147 S haloacid dehalogenase-like hydrolase
MCDHIGFA_01155 5.1e-226 S cog cog1373
MCDHIGFA_01156 6.1e-61 K Transcriptional regulator
MCDHIGFA_01157 6.1e-95 K Transcriptional regulator
MCDHIGFA_01158 3.6e-42 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
MCDHIGFA_01159 1.8e-48 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
MCDHIGFA_01160 3.1e-16 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
MCDHIGFA_01161 2.5e-40 relB L Addiction module antitoxin, RelB DinJ family
MCDHIGFA_01162 3e-232 pbuG S permease
MCDHIGFA_01163 7.8e-129 K helix_turn_helix, mercury resistance
MCDHIGFA_01164 1.1e-148 S ABC-2 family transporter protein
MCDHIGFA_01165 8.2e-79 V ATPases associated with a variety of cellular activities
MCDHIGFA_01166 1.4e-59 K Helix-turn-helix XRE-family like proteins
MCDHIGFA_01167 3e-24 K Helix-turn-helix XRE-family like proteins
MCDHIGFA_01168 2.2e-230 pbuG S permease
MCDHIGFA_01169 2.1e-127 cof S haloacid dehalogenase-like hydrolase
MCDHIGFA_01170 4e-62
MCDHIGFA_01171 4.6e-123 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
MCDHIGFA_01172 4.8e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
MCDHIGFA_01173 0.0 sacX 2.7.1.208, 2.7.1.211 G phosphotransferase system
MCDHIGFA_01174 8.1e-120 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MCDHIGFA_01175 1.6e-189 yfeW 3.4.16.4 V Beta-lactamase
MCDHIGFA_01176 1.7e-145 S Bacterial protein of unknown function (DUF871)
MCDHIGFA_01177 3.4e-99 ybbH_2 K rpiR family
MCDHIGFA_01178 2.4e-274 ytgP S Polysaccharide biosynthesis protein
MCDHIGFA_01179 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MCDHIGFA_01180 7.1e-121 3.6.1.27 I Acid phosphatase homologues
MCDHIGFA_01181 4.5e-166 K LysR substrate binding domain
MCDHIGFA_01182 3.6e-91 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MCDHIGFA_01183 1.1e-231 ndh 1.6.99.3 C NADH dehydrogenase
MCDHIGFA_01184 3e-162 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
MCDHIGFA_01185 5.5e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MCDHIGFA_01186 4.9e-128 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MCDHIGFA_01187 1.4e-269 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MCDHIGFA_01188 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MCDHIGFA_01189 3e-179 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
MCDHIGFA_01190 6.6e-273 cydA 1.10.3.14 C ubiquinol oxidase
MCDHIGFA_01193 7.6e-59 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
MCDHIGFA_01194 2.2e-144 G MFS/sugar transport protein
MCDHIGFA_01195 2.3e-09 aepX 2.7.7.15, 2.7.7.39, 5.4.2.9 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MCDHIGFA_01196 5.6e-38 K Helix-turn-helix XRE-family like proteins
MCDHIGFA_01197 5.9e-12
MCDHIGFA_01198 4.9e-115 4.1.1.44 S Carboxymuconolactone decarboxylase family
MCDHIGFA_01199 3.2e-56 yagE E amino acid
MCDHIGFA_01200 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MCDHIGFA_01201 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MCDHIGFA_01202 9.3e-66 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MCDHIGFA_01203 1.6e-244 cycA E Amino acid permease
MCDHIGFA_01204 1.1e-47 maa S transferase hexapeptide repeat
MCDHIGFA_01205 1.3e-16 maa S transferase hexapeptide repeat
MCDHIGFA_01206 6.7e-159 K Transcriptional regulator
MCDHIGFA_01207 1.3e-63 manO S Domain of unknown function (DUF956)
MCDHIGFA_01208 1e-173 manN G system, mannose fructose sorbose family IID component
MCDHIGFA_01209 1.7e-129 manY G PTS system
MCDHIGFA_01210 5.6e-186 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
MCDHIGFA_01212 6.5e-164 map 3.4.11.18 E Methionine Aminopeptidase
MCDHIGFA_01213 1e-162 yihY S Belongs to the UPF0761 family
MCDHIGFA_01214 2.3e-167 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MCDHIGFA_01215 2.3e-215 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
MCDHIGFA_01216 2.6e-206 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
MCDHIGFA_01217 1.6e-216 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
MCDHIGFA_01218 9.4e-46
MCDHIGFA_01219 6.7e-178 D Alpha beta
MCDHIGFA_01220 1.6e-263 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MCDHIGFA_01221 1.5e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
MCDHIGFA_01222 1.6e-85
MCDHIGFA_01223 1.6e-74
MCDHIGFA_01224 1.1e-140 hlyX S Transporter associated domain
MCDHIGFA_01225 3.6e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MCDHIGFA_01226 8.3e-148
MCDHIGFA_01227 2.1e-264 V ABC transporter transmembrane region
MCDHIGFA_01229 0.0 S membrane
MCDHIGFA_01230 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
MCDHIGFA_01231 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MCDHIGFA_01232 2.1e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MCDHIGFA_01233 2.4e-119 gluP 3.4.21.105 S Rhomboid family
MCDHIGFA_01234 9.7e-36 yqgQ S Bacterial protein of unknown function (DUF910)
MCDHIGFA_01235 1.5e-65 yqhL P Rhodanese-like protein
MCDHIGFA_01236 1.2e-169 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MCDHIGFA_01237 7.6e-225 ynbB 4.4.1.1 P aluminum resistance
MCDHIGFA_01238 2e-263 glnA 6.3.1.2 E glutamine synthetase
MCDHIGFA_01239 4.6e-171
MCDHIGFA_01240 6e-148
MCDHIGFA_01241 9.1e-59 L An automated process has identified a potential problem with this gene model
MCDHIGFA_01242 3.6e-25 L An automated process has identified a potential problem with this gene model
MCDHIGFA_01243 2.7e-225 E Amino acid permease
MCDHIGFA_01244 8.6e-10 E Amino acid permease
MCDHIGFA_01245 2.8e-24 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
MCDHIGFA_01246 2.1e-38 acfD M Membrane
MCDHIGFA_01247 7.1e-144 S response to antibiotic
MCDHIGFA_01248 5.2e-192
MCDHIGFA_01249 4.6e-126 S zinc-ribbon domain
MCDHIGFA_01250 9.8e-77 usp6 T universal stress protein
MCDHIGFA_01251 8.4e-39
MCDHIGFA_01252 2.3e-218 rarA L recombination factor protein RarA
MCDHIGFA_01253 9.9e-85 yueI S Protein of unknown function (DUF1694)
MCDHIGFA_01254 1.4e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MCDHIGFA_01255 3.1e-293 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MCDHIGFA_01256 1.8e-215 iscS2 2.8.1.7 E Aminotransferase class V
MCDHIGFA_01257 9.7e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MCDHIGFA_01259 1.6e-82 K Helix-turn-helix XRE-family like proteins
MCDHIGFA_01260 3.5e-62
MCDHIGFA_01261 9.8e-48 arcA 3.5.3.6 E Arginine
MCDHIGFA_01262 6.3e-63 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MCDHIGFA_01263 1.6e-107 argF 2.1.3.3, 2.7.2.2 E Belongs to the carbamate kinase family
MCDHIGFA_01264 2e-97 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
MCDHIGFA_01265 2.7e-208 S Sterol carrier protein domain
MCDHIGFA_01266 1e-20
MCDHIGFA_01267 2e-109 K LysR substrate binding domain
MCDHIGFA_01268 1.1e-98
MCDHIGFA_01269 1.9e-118 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
MCDHIGFA_01270 8e-95
MCDHIGFA_01271 3.1e-287 V ABC-type multidrug transport system, ATPase and permease components
MCDHIGFA_01272 1.9e-281 V ABC-type multidrug transport system, ATPase and permease components
MCDHIGFA_01273 7.1e-74
MCDHIGFA_01274 2.3e-21 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
MCDHIGFA_01275 2.9e-70 hipB K sequence-specific DNA binding
MCDHIGFA_01276 1.1e-41 S SnoaL-like domain
MCDHIGFA_01277 1.5e-49 L PLD-like domain
MCDHIGFA_01278 0.0 L PLD-like domain
MCDHIGFA_01279 1.7e-76 S DUF218 domain
MCDHIGFA_01280 1.5e-71 S DUF218 domain
MCDHIGFA_01281 0.0 macB_3 V ABC transporter, ATP-binding protein
MCDHIGFA_01282 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MCDHIGFA_01284 2.8e-100 S ECF transporter, substrate-specific component
MCDHIGFA_01285 1.8e-201 tcsA S ABC transporter substrate-binding protein PnrA-like
MCDHIGFA_01286 3.3e-200 tcsA S ABC transporter substrate-binding protein PnrA-like
MCDHIGFA_01287 5.2e-284 xylG 3.6.3.17 S ABC transporter
MCDHIGFA_01288 1.9e-198 yufP S Belongs to the binding-protein-dependent transport system permease family
MCDHIGFA_01289 4.4e-172 yufQ S Belongs to the binding-protein-dependent transport system permease family
MCDHIGFA_01290 6.1e-154 yeaE S Aldo/keto reductase family
MCDHIGFA_01291 1.7e-131 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MCDHIGFA_01292 1.3e-17
MCDHIGFA_01293 6.9e-290 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
MCDHIGFA_01294 8.9e-101 treR K UTRA
MCDHIGFA_01295 2.3e-297 treB G phosphotransferase system
MCDHIGFA_01296 2.8e-64 spxA_2 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MCDHIGFA_01297 7.3e-191 yrvN L AAA C-terminal domain
MCDHIGFA_01298 1.4e-209 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MCDHIGFA_01299 2.8e-84 K Acetyltransferase (GNAT) domain
MCDHIGFA_01300 4.4e-230 S Putative peptidoglycan binding domain
MCDHIGFA_01301 7.5e-95 S ECF-type riboflavin transporter, S component
MCDHIGFA_01302 1.1e-99 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
MCDHIGFA_01303 1.2e-203 pbpX1 V Beta-lactamase
MCDHIGFA_01304 1.4e-115 lacA 2.3.1.79 S Transferase hexapeptide repeat
MCDHIGFA_01305 5.6e-35 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MCDHIGFA_01306 2e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MCDHIGFA_01307 2.6e-244 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
MCDHIGFA_01308 4.2e-24 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
MCDHIGFA_01309 9e-11 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
MCDHIGFA_01310 6.4e-108 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
MCDHIGFA_01311 3.3e-52 S Iron-sulfur cluster assembly protein
MCDHIGFA_01312 1.7e-154 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MCDHIGFA_01313 9e-124 sdaAB 4.3.1.17 E Serine dehydratase beta chain
MCDHIGFA_01314 1.2e-43
MCDHIGFA_01315 2.7e-285 lsa S ABC transporter
MCDHIGFA_01316 3.2e-121 L Transposase
MCDHIGFA_01317 4.1e-86 L Transposase
MCDHIGFA_01318 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
MCDHIGFA_01319 9.6e-86 scrR K Periplasmic binding protein domain
MCDHIGFA_01320 2.1e-219 L Belongs to the 'phage' integrase family
MCDHIGFA_01321 2e-25
MCDHIGFA_01322 1.5e-54
MCDHIGFA_01323 5.1e-145 S Replication initiation factor
MCDHIGFA_01324 3.3e-141 D Ftsk spoiiie family protein
MCDHIGFA_01325 3.3e-87
MCDHIGFA_01326 7.4e-74
MCDHIGFA_01327 3.9e-131 K Helix-turn-helix XRE-family like proteins
MCDHIGFA_01329 2.9e-120 yhiD S MgtC family
MCDHIGFA_01330 3.8e-229 I Protein of unknown function (DUF2974)
MCDHIGFA_01331 1.4e-296 L Transposase
MCDHIGFA_01332 3.5e-15 S Transglycosylase associated protein
MCDHIGFA_01334 6e-168 scrK 2.7.1.2, 2.7.1.4 GK ROK family
MCDHIGFA_01335 5.5e-135 V ABC transporter transmembrane region
MCDHIGFA_01336 5.5e-158 degV S DegV family
MCDHIGFA_01337 1.5e-247 L Putative transposase DNA-binding domain
MCDHIGFA_01338 1.1e-115 L Resolvase, N-terminal
MCDHIGFA_01339 0.0 3.6.3.8 P P-type ATPase
MCDHIGFA_01340 1.6e-163
MCDHIGFA_01341 7.1e-95 K Helix-turn-helix domain
MCDHIGFA_01342 4.9e-15 1.3.5.4 C FAD binding domain
MCDHIGFA_01343 4.9e-63 S Phage derived protein Gp49-like (DUF891)
MCDHIGFA_01344 6e-42 K Helix-turn-helix XRE-family like proteins
MCDHIGFA_01345 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MCDHIGFA_01346 5e-240 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MCDHIGFA_01347 4e-127 S Haloacid dehalogenase-like hydrolase
MCDHIGFA_01348 2.3e-108 radC L DNA repair protein
MCDHIGFA_01349 6.9e-176 mreB D cell shape determining protein MreB
MCDHIGFA_01350 6.7e-148 mreC M Involved in formation and maintenance of cell shape
MCDHIGFA_01351 2.7e-94 mreD
MCDHIGFA_01353 6.4e-54 S Protein of unknown function (DUF3397)
MCDHIGFA_01354 6.3e-78 mraZ K Belongs to the MraZ family
MCDHIGFA_01355 1.3e-176 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MCDHIGFA_01356 4.1e-54 ftsL D Cell division protein FtsL
MCDHIGFA_01357 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
MCDHIGFA_01358 1.5e-175 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MCDHIGFA_01359 7.3e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MCDHIGFA_01360 4.4e-208 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MCDHIGFA_01361 1.6e-152 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MCDHIGFA_01362 2.6e-247 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MCDHIGFA_01363 5.5e-205 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MCDHIGFA_01364 7.3e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MCDHIGFA_01365 1.7e-45 yggT S YGGT family
MCDHIGFA_01366 6.7e-150 ylmH S S4 domain protein
MCDHIGFA_01367 2.8e-74 gpsB D DivIVA domain protein
MCDHIGFA_01368 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MCDHIGFA_01369 3.6e-31 cspA K 'Cold-shock' DNA-binding domain
MCDHIGFA_01370 9.8e-103 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
MCDHIGFA_01371 1.8e-37
MCDHIGFA_01372 2.6e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MCDHIGFA_01373 3.2e-217 iscS 2.8.1.7 E Aminotransferase class V
MCDHIGFA_01374 2.2e-57 XK27_04120 S Putative amino acid metabolism
MCDHIGFA_01375 4.6e-221 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MCDHIGFA_01376 3.9e-127 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
MCDHIGFA_01377 8.3e-106 S Repeat protein
MCDHIGFA_01378 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MCDHIGFA_01379 5.4e-295 L Nuclease-related domain
MCDHIGFA_01380 1.2e-182 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
MCDHIGFA_01381 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MCDHIGFA_01382 4.6e-32 ykzG S Belongs to the UPF0356 family
MCDHIGFA_01383 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MCDHIGFA_01384 0.0 typA T GTP-binding protein TypA
MCDHIGFA_01385 2.7e-211 ftsW D Belongs to the SEDS family
MCDHIGFA_01386 5.1e-54 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
MCDHIGFA_01387 4.5e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
MCDHIGFA_01388 1.3e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MCDHIGFA_01389 1.4e-187 ylbL T Belongs to the peptidase S16 family
MCDHIGFA_01390 1.8e-79 comEA L Competence protein ComEA
MCDHIGFA_01391 0.0 comEC S Competence protein ComEC
MCDHIGFA_01392 9.7e-175 holA 2.7.7.7 L DNA polymerase III delta subunit
MCDHIGFA_01393 6.7e-35 rpsT J Binds directly to 16S ribosomal RNA
MCDHIGFA_01394 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MCDHIGFA_01395 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MCDHIGFA_01396 1.6e-149
MCDHIGFA_01397 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MCDHIGFA_01398 1.3e-38 yagE E amino acid
MCDHIGFA_01399 4.9e-99 yagE E Amino acid permease
MCDHIGFA_01400 3.6e-151 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
MCDHIGFA_01401 8.1e-145 2.4.2.3 F Phosphorylase superfamily
MCDHIGFA_01402 6.9e-144 2.4.2.3 F Phosphorylase superfamily
MCDHIGFA_01403 9.3e-81 S AAA domain
MCDHIGFA_01404 1.7e-120 fbiB 6.3.2.12, 6.3.2.17, 6.3.2.31, 6.3.2.34 S F420-0:Gamma-glutamyl ligase
MCDHIGFA_01405 2.4e-55 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
MCDHIGFA_01406 3e-110 yxaM EGP Major facilitator Superfamily
MCDHIGFA_01407 7.6e-53 yxaM EGP Major facilitator Superfamily
MCDHIGFA_01408 2.8e-140 S Alpha/beta hydrolase family
MCDHIGFA_01409 4.5e-94 rimL J Acetyltransferase (GNAT) domain
MCDHIGFA_01410 1.7e-262
MCDHIGFA_01411 6.8e-120 glsA 3.5.1.2 E Belongs to the glutaminase family
MCDHIGFA_01412 2e-64
MCDHIGFA_01413 4.8e-48 S MazG-like family
MCDHIGFA_01414 7.8e-130 S Protein of unknown function (DUF2785)
MCDHIGFA_01415 2.2e-57 K Acetyltransferase (GNAT) domain
MCDHIGFA_01416 0.0 snf 2.7.11.1 KL domain protein
MCDHIGFA_01417 3.5e-109 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MCDHIGFA_01418 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MCDHIGFA_01419 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MCDHIGFA_01420 1.9e-183 K Transcriptional regulator
MCDHIGFA_01421 7.3e-172 ppaC 3.6.1.1 C inorganic pyrophosphatase
MCDHIGFA_01422 1.1e-112 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MCDHIGFA_01423 4.4e-56 K Helix-turn-helix domain
MCDHIGFA_01424 2.1e-124 ywqD 2.7.10.1 D Capsular exopolysaccharide family
MCDHIGFA_01425 1.4e-144 ywqE 3.1.3.48 GM PHP domain protein
MCDHIGFA_01426 2.2e-122 rfbP M Bacterial sugar transferase
MCDHIGFA_01427 1.5e-147 M Glycosyl transferases group 1
MCDHIGFA_01428 1.4e-129 M Glycosyl transferases group 1
MCDHIGFA_01429 1.6e-47 GT2 M transferase activity, transferring glycosyl groups
MCDHIGFA_01430 5e-183 M Glycosyl transferases group 1
MCDHIGFA_01431 3.4e-50 cps1D M Domain of unknown function (DUF4422)
MCDHIGFA_01433 1.1e-55 MA20_43635 M Capsular polysaccharide synthesis protein
MCDHIGFA_01434 3.2e-190 glf 5.4.99.9 M UDP-galactopyranose mutase
MCDHIGFA_01435 5.6e-256 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
MCDHIGFA_01436 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MCDHIGFA_01437 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MCDHIGFA_01438 1.7e-29 secG U Preprotein translocase
MCDHIGFA_01439 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MCDHIGFA_01440 1.5e-178 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MCDHIGFA_01441 2.6e-202 cpoA GT4 M Glycosyltransferase, group 1 family protein
MCDHIGFA_01442 1.4e-223 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
MCDHIGFA_01470 7.9e-141 ykuT M mechanosensitive ion channel
MCDHIGFA_01471 9.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MCDHIGFA_01472 1.3e-36
MCDHIGFA_01473 9.1e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MCDHIGFA_01474 1.9e-181 ccpA K catabolite control protein A
MCDHIGFA_01475 2.3e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MCDHIGFA_01476 4.3e-55
MCDHIGFA_01477 1.2e-274 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
MCDHIGFA_01478 1.7e-105 yutD S Protein of unknown function (DUF1027)
MCDHIGFA_01479 1.5e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MCDHIGFA_01480 3.7e-100 S Protein of unknown function (DUF1461)
MCDHIGFA_01481 2.3e-116 dedA S SNARE-like domain protein
MCDHIGFA_01482 2.7e-185 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
MCDHIGFA_01483 4.1e-37 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MCDHIGFA_01484 0.0 oppA E ABC transporter substrate-binding protein
MCDHIGFA_01485 1.1e-176 K AI-2E family transporter
MCDHIGFA_01486 3.1e-104 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
MCDHIGFA_01487 2.4e-18
MCDHIGFA_01488 5.2e-248 G Major Facilitator
MCDHIGFA_01489 8.1e-137 XK27_08845 S ABC transporter, ATP-binding protein
MCDHIGFA_01490 2.5e-121 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
MCDHIGFA_01491 2.3e-176 ABC-SBP S ABC transporter
MCDHIGFA_01492 3.5e-134 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MCDHIGFA_01493 2e-141 P CorA-like Mg2+ transporter protein
MCDHIGFA_01494 0.0 UW LPXTG-motif cell wall anchor domain protein
MCDHIGFA_01497 1.6e-211 yttB EGP Major facilitator Superfamily
MCDHIGFA_01498 0.0 pepO 3.4.24.71 O Peptidase family M13
MCDHIGFA_01499 0.0 kup P Transport of potassium into the cell
MCDHIGFA_01500 8.8e-72
MCDHIGFA_01501 2.3e-66 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MCDHIGFA_01502 3.7e-58 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
MCDHIGFA_01503 1.7e-44
MCDHIGFA_01505 5.5e-30
MCDHIGFA_01506 6.9e-38 S Protein of unknown function (DUF2922)
MCDHIGFA_01507 5.9e-174 V Abi-like protein
MCDHIGFA_01508 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MCDHIGFA_01509 2.1e-168 dnaI L Primosomal protein DnaI
MCDHIGFA_01510 3e-251 dnaB L Replication initiation and membrane attachment
MCDHIGFA_01511 3.5e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MCDHIGFA_01512 1.3e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MCDHIGFA_01513 8.5e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MCDHIGFA_01514 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MCDHIGFA_01515 2.6e-301 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
MCDHIGFA_01516 1.4e-62
MCDHIGFA_01517 2.2e-259 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
MCDHIGFA_01518 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
MCDHIGFA_01519 3.6e-177 lacI3 K helix_turn _helix lactose operon repressor
MCDHIGFA_01520 7.4e-233 malE G Bacterial extracellular solute-binding protein
MCDHIGFA_01521 8.1e-175 O Belongs to the peptidase S8 family
MCDHIGFA_01522 6e-38 L Transposase and inactivated derivatives, IS30 family
MCDHIGFA_01523 1.7e-24 S SLAP domain
MCDHIGFA_01528 5.7e-11 S Single-strand binding protein family
MCDHIGFA_01538 2.6e-26 S Domain of unknown function (DUF771)
MCDHIGFA_01539 4.9e-30 K Helix-turn-helix domain
MCDHIGFA_01540 1.3e-20 XK27_07105 K Helix-turn-helix XRE-family like proteins
MCDHIGFA_01541 2.2e-25 K Helix-turn-helix domain
MCDHIGFA_01542 3.4e-09 S Pfam:DUF955
MCDHIGFA_01543 5e-151 L Belongs to the 'phage' integrase family
MCDHIGFA_01545 5.4e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MCDHIGFA_01546 4.6e-188 ytxK 2.1.1.72 L N-6 DNA Methylase
MCDHIGFA_01547 1.6e-21
MCDHIGFA_01548 3.8e-77 comGF U Putative Competence protein ComGF
MCDHIGFA_01549 2.3e-41
MCDHIGFA_01550 7.4e-71
MCDHIGFA_01551 3.1e-43 comGC U competence protein ComGC
MCDHIGFA_01552 2.7e-172 comGB NU type II secretion system
MCDHIGFA_01553 2.4e-178 comGA NU Type II IV secretion system protein
MCDHIGFA_01554 8.9e-133 yebC K Transcriptional regulatory protein
MCDHIGFA_01555 2e-94 S VanZ like family
MCDHIGFA_01556 3.2e-110 ylbE GM NAD(P)H-binding
MCDHIGFA_01557 9.8e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MCDHIGFA_01559 4.5e-302 E Amino acid permease
MCDHIGFA_01560 1.4e-173 D Alpha beta
MCDHIGFA_01561 2.6e-301 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MCDHIGFA_01562 0.0 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
MCDHIGFA_01563 5.4e-142 licT K CAT RNA binding domain
MCDHIGFA_01564 4.5e-208 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MCDHIGFA_01565 7.4e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MCDHIGFA_01566 1.6e-118
MCDHIGFA_01567 1.1e-74 K Penicillinase repressor
MCDHIGFA_01568 1.4e-147 S hydrolase
MCDHIGFA_01569 3.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MCDHIGFA_01570 2e-172 ybbR S YbbR-like protein
MCDHIGFA_01571 6.4e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MCDHIGFA_01572 2.3e-206 potD P ABC transporter
MCDHIGFA_01573 2.1e-127 potC P ABC transporter permease
MCDHIGFA_01574 5.4e-131 potB P ABC transporter permease
MCDHIGFA_01575 4.1e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MCDHIGFA_01576 1.8e-164 murB 1.3.1.98 M Cell wall formation
MCDHIGFA_01577 4e-98 dnaQ 2.7.7.7 L DNA polymerase III
MCDHIGFA_01578 1.4e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
MCDHIGFA_01579 3.1e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MCDHIGFA_01580 9.7e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MCDHIGFA_01581 1.4e-156 ycsE S Sucrose-6F-phosphate phosphohydrolase
MCDHIGFA_01582 1.2e-94
MCDHIGFA_01583 1.7e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MCDHIGFA_01584 1e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MCDHIGFA_01585 6.5e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MCDHIGFA_01586 1.1e-189 cggR K Putative sugar-binding domain
MCDHIGFA_01588 9.8e-291
MCDHIGFA_01589 7.8e-274 ycaM E amino acid
MCDHIGFA_01590 9.6e-141 S Cysteine-rich secretory protein family
MCDHIGFA_01591 6.9e-34 S Protein of unknown function (DUF3021)
MCDHIGFA_01592 3.9e-46 K LytTr DNA-binding domain
MCDHIGFA_01593 8.9e-92 cylB V ABC-2 type transporter
MCDHIGFA_01594 1.8e-116 cylA V ABC transporter
MCDHIGFA_01595 5.4e-77 K MerR HTH family regulatory protein
MCDHIGFA_01596 3.2e-262 lmrB EGP Major facilitator Superfamily
MCDHIGFA_01597 2.3e-96 S Domain of unknown function (DUF4811)
MCDHIGFA_01598 1.9e-130 ybbM S Uncharacterised protein family (UPF0014)
MCDHIGFA_01599 4.9e-111 ybbL S ABC transporter, ATP-binding protein
MCDHIGFA_01600 3.3e-250 malF P Binding-protein-dependent transport system inner membrane component
MCDHIGFA_01601 4e-210 malE G Bacterial extracellular solute-binding protein
MCDHIGFA_01602 9.5e-211 msmX P Belongs to the ABC transporter superfamily
MCDHIGFA_01603 1.2e-115 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
MCDHIGFA_01604 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
MCDHIGFA_01605 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
MCDHIGFA_01606 8e-108 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
MCDHIGFA_01607 1.7e-18 S Bacterial protein of unknown function (DUF871)
MCDHIGFA_01608 3.4e-142 S Bacterial protein of unknown function (DUF871)
MCDHIGFA_01609 4.1e-214 2.7.1.208, 2.7.1.211 G phosphotransferase system
MCDHIGFA_01610 3.7e-120 S Putative esterase
MCDHIGFA_01611 1.4e-119 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MCDHIGFA_01612 1.3e-79 ybbH_2 K Helix-turn-helix domain, rpiR family
MCDHIGFA_01613 3.5e-261 qacA EGP Major facilitator Superfamily
MCDHIGFA_01614 7.9e-219 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MCDHIGFA_01617 2.6e-166 psaA P Belongs to the bacterial solute-binding protein 9 family
MCDHIGFA_01619 6.5e-190 UW LPXTG-motif cell wall anchor domain protein
MCDHIGFA_01620 7.7e-27 UW LPXTG-motif cell wall anchor domain protein
MCDHIGFA_01621 3.2e-52 UW LPXTG-motif cell wall anchor domain protein
MCDHIGFA_01622 2.5e-45 UW LPXTG-motif cell wall anchor domain protein
MCDHIGFA_01623 3.9e-98 UW LPXTG-motif cell wall anchor domain protein
MCDHIGFA_01624 1.9e-247 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MCDHIGFA_01625 7.5e-100 J Acetyltransferase (GNAT) domain
MCDHIGFA_01626 1.8e-110 yjbF S SNARE associated Golgi protein
MCDHIGFA_01627 7.1e-152 I alpha/beta hydrolase fold
MCDHIGFA_01628 1.5e-158 hipB K Helix-turn-helix
MCDHIGFA_01629 2.3e-67 S cog cog1373
MCDHIGFA_01630 1.5e-126 S Alpha/beta hydrolase family
MCDHIGFA_01631 8.3e-156 epsV 2.7.8.12 S glycosyl transferase family 2
MCDHIGFA_01632 4.4e-140 ypuA S Protein of unknown function (DUF1002)
MCDHIGFA_01633 9.7e-146 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MCDHIGFA_01634 1.6e-182 S Alpha/beta hydrolase of unknown function (DUF915)
MCDHIGFA_01635 9.3e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MCDHIGFA_01636 4.2e-86
MCDHIGFA_01637 1e-133 cobB K SIR2 family
MCDHIGFA_01638 2.7e-88 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
MCDHIGFA_01639 9.6e-125 terC P Integral membrane protein TerC family
MCDHIGFA_01640 7.5e-64 yeaO S Protein of unknown function, DUF488
MCDHIGFA_01641 2.4e-115 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
MCDHIGFA_01642 7.1e-239 msmE G Bacterial extracellular solute-binding protein
MCDHIGFA_01643 4e-156 msmF P Binding-protein-dependent transport system inner membrane component
MCDHIGFA_01644 5.2e-153 msmG P Binding-protein-dependent transport system inner membrane component
MCDHIGFA_01645 2.8e-210 msmX P Belongs to the ABC transporter superfamily
MCDHIGFA_01646 0.0 rafA 3.2.1.22 G alpha-galactosidase
MCDHIGFA_01647 1.5e-280 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
MCDHIGFA_01648 5.1e-113 2.7.6.5 T Region found in RelA / SpoT proteins
MCDHIGFA_01649 3.3e-34 K response regulator
MCDHIGFA_01650 3.9e-93 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MCDHIGFA_01651 6.5e-107 3.2.2.20 K acetyltransferase
MCDHIGFA_01653 1.4e-82 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MCDHIGFA_01654 3.5e-37 KQ helix_turn_helix, mercury resistance
MCDHIGFA_01655 3.8e-53
MCDHIGFA_01656 2e-42 S RelB antitoxin
MCDHIGFA_01657 4.9e-69 S HicB_like antitoxin of bacterial toxin-antitoxin system
MCDHIGFA_01658 5.1e-15 N HicA toxin of bacterial toxin-antitoxin,
MCDHIGFA_01659 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
MCDHIGFA_01660 3.1e-79 M Protein of unknown function (DUF3737)
MCDHIGFA_01661 5.4e-225 patB 4.4.1.8 E Aminotransferase, class I
MCDHIGFA_01662 3.6e-190 manA 5.3.1.8 G mannose-6-phosphate isomerase
MCDHIGFA_01663 7.7e-67 S SdpI/YhfL protein family
MCDHIGFA_01664 2e-129 K Transcriptional regulatory protein, C terminal
MCDHIGFA_01665 1.6e-266 yclK 2.7.13.3, 4.6.1.1 T Histidine kinase
MCDHIGFA_01666 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MCDHIGFA_01667 8.5e-105 vanZ V VanZ like family
MCDHIGFA_01669 3.6e-65 K response regulator
MCDHIGFA_01670 6.2e-222 sptS 2.7.13.3 T Histidine kinase
MCDHIGFA_01671 2.5e-209 EGP Major facilitator Superfamily
MCDHIGFA_01672 5e-69 O OsmC-like protein
MCDHIGFA_01673 2.6e-94 S Protein of unknown function (DUF805)
MCDHIGFA_01674 2.2e-78
MCDHIGFA_01675 3.6e-257
MCDHIGFA_01676 2.6e-42 S Fic/DOC family
MCDHIGFA_01677 9.6e-29 S Fic/DOC family
MCDHIGFA_01678 9.6e-275 yjeM E Amino Acid
MCDHIGFA_01679 3e-290 P ABC transporter
MCDHIGFA_01680 5.1e-37
MCDHIGFA_01682 9.5e-126 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
MCDHIGFA_01683 1.3e-87 K GNAT family
MCDHIGFA_01684 8.4e-204 XK27_00915 C Luciferase-like monooxygenase
MCDHIGFA_01685 1.4e-171 lmrB EGP Major facilitator Superfamily
MCDHIGFA_01686 9.5e-34 rmaI K Transcriptional regulator
MCDHIGFA_01687 2.1e-39 K Bacterial regulatory helix-turn-helix protein, lysR family
MCDHIGFA_01688 1e-84 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MCDHIGFA_01690 6.4e-22 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
MCDHIGFA_01691 2.2e-21
MCDHIGFA_01692 3e-62 L PFAM IS66 Orf2 family protein
MCDHIGFA_01693 2.9e-254 L Transposase IS66 family
MCDHIGFA_01694 2.6e-217 naiP EGP Major facilitator Superfamily
MCDHIGFA_01695 3.6e-277 S C4-dicarboxylate anaerobic carrier
MCDHIGFA_01696 9.3e-112
MCDHIGFA_01697 4.7e-57 1.14.99.57 S Antibiotic biosynthesis monooxygenase
MCDHIGFA_01698 1.6e-73 yjaB_1 K Acetyltransferase (GNAT) domain
MCDHIGFA_01699 1e-223 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
MCDHIGFA_01700 1.9e-112 plsC 2.3.1.51 I Acyltransferase
MCDHIGFA_01701 3.1e-192 yabB 2.1.1.223 L Methyltransferase small domain
MCDHIGFA_01702 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
MCDHIGFA_01703 1.6e-183 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MCDHIGFA_01704 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MCDHIGFA_01705 5.3e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MCDHIGFA_01706 1.6e-137 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MCDHIGFA_01707 9.6e-136 cdsA 2.7.7.41 I Belongs to the CDS family
MCDHIGFA_01708 7.5e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
MCDHIGFA_01709 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MCDHIGFA_01710 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MCDHIGFA_01711 2.7e-82 rimP J Required for maturation of 30S ribosomal subunits
MCDHIGFA_01712 2.6e-198 nusA K Participates in both transcription termination and antitermination
MCDHIGFA_01713 8.8e-47 ylxR K Protein of unknown function (DUF448)
MCDHIGFA_01714 3.2e-47 rplGA J ribosomal protein
MCDHIGFA_01715 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MCDHIGFA_01716 3e-60 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MCDHIGFA_01717 3.4e-158 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MCDHIGFA_01718 1.7e-176 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MCDHIGFA_01719 4.5e-194 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MCDHIGFA_01720 2.3e-67 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MCDHIGFA_01721 0.0 dnaK O Heat shock 70 kDa protein
MCDHIGFA_01722 2.9e-202 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MCDHIGFA_01723 9.3e-80 apfA 2.7.7.72, 3.6.1.61 F NUDIX domain
MCDHIGFA_01724 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MCDHIGFA_01725 8.1e-112 srtA 3.4.22.70 M sortase family
MCDHIGFA_01726 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MCDHIGFA_01727 9.1e-80 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MCDHIGFA_01728 4.3e-202 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
MCDHIGFA_01729 1.2e-210 S Bacterial protein of unknown function (DUF871)
MCDHIGFA_01731 5.6e-40 ybhL S Belongs to the BI1 family
MCDHIGFA_01732 1.4e-50 S Metal binding domain of Ada
MCDHIGFA_01733 0.0 mgtA 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
MCDHIGFA_01734 6.9e-137 lysR5 K LysR substrate binding domain
MCDHIGFA_01735 8e-157 arcA 3.5.3.6 E Arginine
MCDHIGFA_01736 4e-101 pgm3 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
MCDHIGFA_01737 2.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
MCDHIGFA_01738 5.2e-281 thrC 4.2.3.1 E Threonine synthase
MCDHIGFA_01739 2.5e-220 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
MCDHIGFA_01740 5e-159 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MCDHIGFA_01741 1.3e-114
MCDHIGFA_01742 3e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MCDHIGFA_01743 7e-136 K Helix-turn-helix XRE-family like proteins
MCDHIGFA_01744 3.3e-20
MCDHIGFA_01745 5e-88
MCDHIGFA_01746 3.6e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MCDHIGFA_01747 1.7e-292 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MCDHIGFA_01748 6.3e-145 ptp2 3.1.3.48 T Tyrosine phosphatase family
MCDHIGFA_01749 8.2e-179 yvdE K helix_turn _helix lactose operon repressor
MCDHIGFA_01750 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MCDHIGFA_01751 4.8e-78 S PAS domain
MCDHIGFA_01752 5.3e-34 rapZ S Displays ATPase and GTPase activities
MCDHIGFA_01753 1.1e-90 S Short repeat of unknown function (DUF308)
MCDHIGFA_01754 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MCDHIGFA_01755 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MCDHIGFA_01756 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MCDHIGFA_01757 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
MCDHIGFA_01758 6.7e-245 ynbB 4.4.1.1 P aluminum resistance
MCDHIGFA_01759 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
MCDHIGFA_01760 2.2e-284 E Amino acid permease
MCDHIGFA_01761 1.6e-93 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
MCDHIGFA_01762 7e-180 lacX 5.1.3.3 G Aldose 1-epimerase
MCDHIGFA_01763 2.6e-61 C Aldo keto reductase
MCDHIGFA_01764 3.7e-44 S aldo-keto reductase (NADP) activity
MCDHIGFA_01765 1.8e-66 M LysM domain protein
MCDHIGFA_01766 1.1e-152 xerD L Phage integrase, N-terminal SAM-like domain
MCDHIGFA_01767 7.9e-67 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MCDHIGFA_01768 2.7e-64 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MCDHIGFA_01769 2.9e-13 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
MCDHIGFA_01770 1.2e-116 mmuP E amino acid
MCDHIGFA_01771 2e-274 pepV 3.5.1.18 E dipeptidase PepV
MCDHIGFA_01772 3.1e-235 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MCDHIGFA_01773 1.9e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MCDHIGFA_01774 2.2e-141 xerC D Phage integrase, N-terminal SAM-like domain
MCDHIGFA_01775 1.8e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MCDHIGFA_01776 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MCDHIGFA_01777 4.7e-152 dprA LU DNA protecting protein DprA
MCDHIGFA_01778 4.1e-07 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MCDHIGFA_01779 2.9e-44
MCDHIGFA_01780 1.5e-94 S Protein of unknown function (DUF3990)
MCDHIGFA_01781 6.2e-171 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
MCDHIGFA_01782 2.1e-65 2.4.1.83 GT2 S GtrA-like protein
MCDHIGFA_01783 9.1e-28 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MCDHIGFA_01784 4.9e-120 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MCDHIGFA_01785 2.5e-183 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
MCDHIGFA_01786 2.5e-165
MCDHIGFA_01787 4.6e-55
MCDHIGFA_01788 1e-98 M ErfK YbiS YcfS YnhG
MCDHIGFA_01789 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MCDHIGFA_01790 6e-171 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
MCDHIGFA_01791 2.2e-96 3.6.1.55 L NUDIX domain
MCDHIGFA_01792 1.1e-76 menA 2.5.1.74 H UbiA prenyltransferase family
MCDHIGFA_01793 2.2e-15
MCDHIGFA_01794 4.6e-17
MCDHIGFA_01795 4.4e-149 L Transposase
MCDHIGFA_01796 1.6e-77 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MCDHIGFA_01797 4.3e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MCDHIGFA_01798 1.2e-107 hlyIII S protein, hemolysin III
MCDHIGFA_01799 2e-144 DegV S Uncharacterised protein, DegV family COG1307
MCDHIGFA_01800 7.1e-36 yozE S Belongs to the UPF0346 family
MCDHIGFA_01801 3.4e-37 yjcE P NhaP-type Na H and K H
MCDHIGFA_01802 1e-178 yjcE P Sodium proton antiporter
MCDHIGFA_01803 2.5e-155 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MCDHIGFA_01804 1.3e-131 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MCDHIGFA_01805 1.4e-24 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MCDHIGFA_01807 1.7e-232 L COG3547 Transposase and inactivated derivatives
MCDHIGFA_01808 9.6e-17 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
MCDHIGFA_01809 2e-146 S Putative ABC-transporter type IV
MCDHIGFA_01810 1.4e-06 S LPXTG cell wall anchor motif
MCDHIGFA_01811 2e-29
MCDHIGFA_01813 6.3e-59
MCDHIGFA_01814 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MCDHIGFA_01815 1.4e-107 M Transport protein ComB
MCDHIGFA_01816 6.7e-131 blpT
MCDHIGFA_01819 2.5e-79
MCDHIGFA_01820 8.2e-31 yozG K Transcriptional regulator
MCDHIGFA_01821 4.8e-25
MCDHIGFA_01822 4.4e-68
MCDHIGFA_01823 3.6e-08
MCDHIGFA_01824 4.9e-29
MCDHIGFA_01825 9.2e-164 natA S ABC transporter, ATP-binding protein
MCDHIGFA_01826 2.7e-219 natB CP ABC-2 family transporter protein
MCDHIGFA_01827 1.8e-136 fruR K DeoR C terminal sensor domain
MCDHIGFA_01828 2.2e-168 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MCDHIGFA_01829 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
MCDHIGFA_01830 5.4e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
MCDHIGFA_01831 4.9e-149 psaA P Belongs to the bacterial solute-binding protein 9 family
MCDHIGFA_01832 1.6e-117 fhuC P ABC transporter
MCDHIGFA_01833 5e-129 znuB U ABC 3 transport family
MCDHIGFA_01834 4.5e-264 lctP C L-lactate permease
MCDHIGFA_01835 3.3e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MCDHIGFA_01836 7.6e-216 2.1.1.14 E methionine synthase, vitamin-B12 independent
MCDHIGFA_01837 4.3e-11
MCDHIGFA_01838 5.5e-29 K Helix-turn-helix XRE-family like proteins
MCDHIGFA_01839 7.2e-136 S CAAX amino terminal protease
MCDHIGFA_01840 4.6e-42 S Enterocin A Immunity
MCDHIGFA_01841 1.1e-68 doc S Prophage maintenance system killer protein
MCDHIGFA_01842 2.9e-31
MCDHIGFA_01844 0.0 pepF E oligoendopeptidase F
MCDHIGFA_01845 7.1e-199 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MCDHIGFA_01846 7.4e-121 S Protein of unknown function (DUF554)
MCDHIGFA_01847 1.1e-95
MCDHIGFA_01848 2.2e-102 rimL J Acetyltransferase (GNAT) domain
MCDHIGFA_01849 2.9e-58
MCDHIGFA_01850 9.2e-289 S ABC transporter
MCDHIGFA_01851 1.4e-136 thrE S Putative threonine/serine exporter
MCDHIGFA_01852 8.7e-84 S Threonine/Serine exporter, ThrE
MCDHIGFA_01853 2.4e-112 yvpB S Peptidase_C39 like family
MCDHIGFA_01854 8.6e-69
MCDHIGFA_01855 4.4e-177 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MCDHIGFA_01856 8.9e-30 nrdI F NrdI Flavodoxin like
MCDHIGFA_01857 7.4e-112
MCDHIGFA_01858 1.9e-278 S O-antigen ligase like membrane protein
MCDHIGFA_01859 2.3e-42
MCDHIGFA_01860 6.7e-93 gmk2 2.7.4.8 F Guanylate kinase homologues.
MCDHIGFA_01861 1e-80 M NlpC/P60 family
MCDHIGFA_01862 1.4e-136 M NlpC P60 family protein
MCDHIGFA_01863 2.6e-118 M NlpC/P60 family
MCDHIGFA_01864 1.6e-41
MCDHIGFA_01866 7.5e-178 S Cysteine-rich secretory protein family
MCDHIGFA_01867 2.7e-222 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MCDHIGFA_01869 1.3e-41 relB L RelB antitoxin
MCDHIGFA_01870 1.3e-47 yoeB S YoeB-like toxin of bacterial type II toxin-antitoxin system
MCDHIGFA_01871 2.5e-176 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MCDHIGFA_01872 1.4e-148 epsB M biosynthesis protein
MCDHIGFA_01873 3.5e-36 2.7.1.191 G PTS system fructose IIA component
MCDHIGFA_01874 6.2e-42
MCDHIGFA_01875 7.7e-09
MCDHIGFA_01876 4.2e-186 ansA 3.5.1.1 EJ L-asparaginase, type I
MCDHIGFA_01877 1.8e-136 glvR K Helix-turn-helix domain, rpiR family
MCDHIGFA_01878 2.7e-268 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
MCDHIGFA_01879 1.8e-153
MCDHIGFA_01881 1.4e-66 yslB S Protein of unknown function (DUF2507)
MCDHIGFA_01882 1e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MCDHIGFA_01883 1.1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MCDHIGFA_01884 1.7e-39 ropB K Helix-turn-helix domain
MCDHIGFA_01885 1.6e-112
MCDHIGFA_01886 2.6e-140
MCDHIGFA_01887 1.5e-99 V ATPases associated with a variety of cellular activities
MCDHIGFA_01888 7.5e-91 S Domain of unknown function (DUF4767)
MCDHIGFA_01889 1.5e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MCDHIGFA_01890 1.9e-147 yitS S Uncharacterised protein, DegV family COG1307
MCDHIGFA_01891 1.2e-100 3.6.1.27 I Acid phosphatase homologues
MCDHIGFA_01892 5.1e-192 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MCDHIGFA_01894 1.7e-83 MA20_14895 S Conserved hypothetical protein 698
MCDHIGFA_01895 7.3e-84 MA20_14895 S Conserved hypothetical protein 698
MCDHIGFA_01896 2.8e-120 lsa S ABC transporter
MCDHIGFA_01897 1.6e-202 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MCDHIGFA_01898 4e-107 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
MCDHIGFA_01899 2.6e-227 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
MCDHIGFA_01900 1.9e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MCDHIGFA_01901 2.4e-10 L Psort location Cytoplasmic, score
MCDHIGFA_01902 2.6e-183 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MCDHIGFA_01903 1.7e-139 noxC 1.5.1.39 C coenzyme F420-1:gamma-L-glutamate ligase activity
MCDHIGFA_01904 1.1e-215 EGP Major Facilitator Superfamily
MCDHIGFA_01905 4.9e-31 S ATP diphosphatase activity
MCDHIGFA_01908 1.6e-71 K Helix-turn-helix domain
MCDHIGFA_01909 2.8e-112 S Protein of unknown function (DUF1211)
MCDHIGFA_01910 1.5e-75 ltrA S Bacterial low temperature requirement A protein (LtrA)
MCDHIGFA_01911 2.8e-119 3.6.1.55 F NUDIX domain
MCDHIGFA_01912 7.3e-245 brnQ U Component of the transport system for branched-chain amino acids
MCDHIGFA_01913 0.0 L Plasmid pRiA4b ORF-3-like protein
MCDHIGFA_01915 3.5e-206 M Glycosyl hydrolases family 25
MCDHIGFA_01916 6.9e-156 cinI S Serine hydrolase (FSH1)
MCDHIGFA_01917 7.1e-301 S Predicted membrane protein (DUF2207)
MCDHIGFA_01918 2.8e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
MCDHIGFA_01920 2.1e-120 rapZ S Displays ATPase and GTPase activities
MCDHIGFA_01921 4e-195 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MCDHIGFA_01922 4.7e-171 whiA K May be required for sporulation
MCDHIGFA_01923 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MCDHIGFA_01924 0.0 S SH3-like domain
MCDHIGFA_01925 8.1e-154 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MCDHIGFA_01926 3.3e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MCDHIGFA_01928 1.8e-45 pspC KT PspC domain
MCDHIGFA_01929 1.1e-106 S domain, Protein
MCDHIGFA_01930 9.8e-10
MCDHIGFA_01931 7.3e-50 L Transposase
MCDHIGFA_01932 3.5e-31
MCDHIGFA_01933 2.3e-44 XK27_09445 S Domain of unknown function (DUF1827)
MCDHIGFA_01934 0.0 clpE O Belongs to the ClpA ClpB family
MCDHIGFA_01935 5.3e-26
MCDHIGFA_01936 4e-248 yjjP S Putative threonine/serine exporter
MCDHIGFA_01937 8.2e-85 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MCDHIGFA_01938 2.5e-175 prmA J Ribosomal protein L11 methyltransferase
MCDHIGFA_01939 2.9e-60
MCDHIGFA_01940 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MCDHIGFA_01941 6e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MCDHIGFA_01942 6.8e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
MCDHIGFA_01943 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MCDHIGFA_01944 9.8e-222 patA 2.6.1.1 E Aminotransferase
MCDHIGFA_01945 1.8e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MCDHIGFA_01946 2.9e-156 S reductase
MCDHIGFA_01947 2e-149 yxeH S hydrolase
MCDHIGFA_01948 2.3e-181 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MCDHIGFA_01949 6.9e-243 yfnA E Amino Acid
MCDHIGFA_01950 1.8e-110 dedA 3.1.3.1 S SNARE associated Golgi protein
MCDHIGFA_01951 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MCDHIGFA_01952 1.7e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MCDHIGFA_01953 3.7e-295 I Acyltransferase
MCDHIGFA_01954 5.8e-177 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MCDHIGFA_01955 1.6e-143 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MCDHIGFA_01956 1.5e-34 yrvD S Lipopolysaccharide assembly protein A domain
MCDHIGFA_01957 1.3e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MCDHIGFA_01958 9e-308 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
MCDHIGFA_01959 2.3e-23 S Protein of unknown function (DUF2929)
MCDHIGFA_01960 0.0 dnaE 2.7.7.7 L DNA polymerase
MCDHIGFA_01961 3.3e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MCDHIGFA_01962 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MCDHIGFA_01963 1.9e-169 cvfB S S1 domain
MCDHIGFA_01964 3.1e-167 xerD D recombinase XerD
MCDHIGFA_01965 2.6e-61 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MCDHIGFA_01966 7.6e-132 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MCDHIGFA_01967 4.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MCDHIGFA_01968 1.5e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MCDHIGFA_01969 8.7e-114 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MCDHIGFA_01970 2.7e-18 M Lysin motif
MCDHIGFA_01971 8.5e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MCDHIGFA_01972 5.5e-212 rpsA 1.17.7.4 J Ribosomal protein S1
MCDHIGFA_01973 1.9e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MCDHIGFA_01974 2.3e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MCDHIGFA_01975 8.7e-229 S Tetratricopeptide repeat protein
MCDHIGFA_01976 5.8e-288 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MCDHIGFA_01977 1.4e-279 V ABC transporter transmembrane region
MCDHIGFA_01978 2.2e-49
MCDHIGFA_01979 1.5e-90 speG J Acetyltransferase (GNAT) domain
MCDHIGFA_01980 9.4e-207 hsdM 2.1.1.72 V type I restriction-modification system
MCDHIGFA_01981 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
MCDHIGFA_01982 7.6e-98 3.5.1.28 UW LPXTG-motif cell wall anchor domain protein
MCDHIGFA_01983 4.2e-150
MCDHIGFA_01985 4.1e-98 ydaM M Glycosyl transferase
MCDHIGFA_01986 1.1e-139 ydaM M Glycosyl transferase
MCDHIGFA_01987 2.7e-188 G Glycosyl hydrolases family 8
MCDHIGFA_01988 5e-39 relB L RelB antitoxin
MCDHIGFA_01989 1.1e-34 S Bacterial toxin of type II toxin-antitoxin system, YafQ
MCDHIGFA_01990 6.5e-82 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
MCDHIGFA_01991 1.9e-241 V N-6 DNA Methylase
MCDHIGFA_01992 4.1e-189 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
MCDHIGFA_01993 0.0 uvrA3 L excinuclease ABC, A subunit
MCDHIGFA_01994 1.3e-81 C Flavodoxin
MCDHIGFA_01995 7.8e-261 emrY EGP Major facilitator Superfamily
MCDHIGFA_01996 4.7e-91 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MCDHIGFA_01997 2.9e-238 pyrP F Permease
MCDHIGFA_01998 2.1e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MCDHIGFA_01999 4.8e-96 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MCDHIGFA_02000 1.1e-175 phoH T phosphate starvation-inducible protein PhoH
MCDHIGFA_02001 1.6e-71 yqeY S YqeY-like protein
MCDHIGFA_02002 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MCDHIGFA_02003 1.1e-59 pdxH S Pyridoxamine 5'-phosphate oxidase
MCDHIGFA_02004 5e-237 XK27_01810 S Calcineurin-like phosphoesterase
MCDHIGFA_02008 1e-151 S AAA ATPase domain
MCDHIGFA_02010 1.8e-45 dam2 2.1.1.72 L DNA methyltransferase
MCDHIGFA_02011 5e-116 L PFAM Integrase catalytic
MCDHIGFA_02012 1.1e-118 clcA P chloride
MCDHIGFA_02013 1.6e-60 clcA P chloride
MCDHIGFA_02014 3.5e-33 K FCD
MCDHIGFA_02015 5.5e-14 K FCD
MCDHIGFA_02018 3.6e-63
MCDHIGFA_02019 1.4e-34
MCDHIGFA_02020 1.9e-115 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
MCDHIGFA_02021 3.4e-79
MCDHIGFA_02022 1e-242 cpdA S Calcineurin-like phosphoesterase
MCDHIGFA_02023 1.8e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MCDHIGFA_02024 1.1e-68 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MCDHIGFA_02025 1e-107 ypsA S Belongs to the UPF0398 family
MCDHIGFA_02026 4.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MCDHIGFA_02027 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
MCDHIGFA_02028 2.7e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MCDHIGFA_02029 1.3e-114 dnaD L DnaD domain protein
MCDHIGFA_02030 5.8e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
MCDHIGFA_02031 2.4e-89 ypmB S Protein conserved in bacteria
MCDHIGFA_02032 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MCDHIGFA_02033 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MCDHIGFA_02034 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MCDHIGFA_02035 2.2e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
MCDHIGFA_02036 1.4e-178 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
MCDHIGFA_02037 1.5e-200 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
MCDHIGFA_02038 8.2e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MCDHIGFA_02039 4.4e-117 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
MCDHIGFA_02040 4.4e-266 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
MCDHIGFA_02041 4.8e-168
MCDHIGFA_02042 1.8e-144
MCDHIGFA_02043 8.8e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MCDHIGFA_02044 2.5e-26
MCDHIGFA_02045 4.3e-39 ybjQ S Belongs to the UPF0145 family
MCDHIGFA_02046 6.2e-80
MCDHIGFA_02047 3e-105
MCDHIGFA_02048 6.2e-122
MCDHIGFA_02049 2.4e-122 skfE V ATPases associated with a variety of cellular activities
MCDHIGFA_02050 6.9e-57 yvoA_1 K Transcriptional regulator, GntR family
MCDHIGFA_02051 3.5e-238 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MCDHIGFA_02052 1.1e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MCDHIGFA_02053 1.2e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
MCDHIGFA_02054 4.8e-81 mutT 3.6.1.55 F NUDIX domain
MCDHIGFA_02055 8e-128 S Peptidase family M23
MCDHIGFA_02056 9.9e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MCDHIGFA_02057 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MCDHIGFA_02058 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MCDHIGFA_02059 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MCDHIGFA_02060 4e-136 recO L Involved in DNA repair and RecF pathway recombination

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)