ORF_ID e_value Gene_name EC_number CAZy COGs Description
NCIMKDED_00001 1.9e-41 prtS 3.4.21.110, 3.4.21.96 O Belongs to the peptidase S8 family
NCIMKDED_00002 1.2e-142 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NCIMKDED_00004 7.6e-39 KQ helix_turn_helix, mercury resistance
NCIMKDED_00005 9.5e-81 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NCIMKDED_00007 2.5e-106 3.2.2.20 K acetyltransferase
NCIMKDED_00008 2e-157 S Archaea bacterial proteins of unknown function
NCIMKDED_00009 1.1e-90 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NCIMKDED_00010 8.4e-24
NCIMKDED_00011 1.1e-150
NCIMKDED_00012 2.7e-268 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
NCIMKDED_00013 1.8e-136 glvR K Helix-turn-helix domain, rpiR family
NCIMKDED_00014 1.5e-186 ansA 3.5.1.1 EJ L-asparaginase, type I
NCIMKDED_00015 7.7e-09
NCIMKDED_00016 5.2e-41
NCIMKDED_00017 8.7e-66 2.7.1.191 G PTS system fructose IIA component
NCIMKDED_00018 0.0 3.6.3.8 P P-type ATPase
NCIMKDED_00019 1.9e-124
NCIMKDED_00020 1.4e-242 S response to antibiotic
NCIMKDED_00021 1.4e-126 pgm3 G Phosphoglycerate mutase family
NCIMKDED_00022 5.6e-118 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
NCIMKDED_00023 0.0 helD 3.6.4.12 L DNA helicase
NCIMKDED_00024 3.2e-110 glnP P ABC transporter permease
NCIMKDED_00025 1.6e-106 glnQ 3.6.3.21 E ABC transporter
NCIMKDED_00026 8.7e-145 aatB ET ABC transporter substrate-binding protein
NCIMKDED_00027 1.6e-71 yjcF S Acetyltransferase (GNAT) domain
NCIMKDED_00028 1.4e-98 E GDSL-like Lipase/Acylhydrolase
NCIMKDED_00029 2.1e-171 coaA 2.7.1.33 F Pantothenic acid kinase
NCIMKDED_00030 4.4e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NCIMKDED_00031 1.5e-101 S Peptidase propeptide and YPEB domain
NCIMKDED_00032 9.9e-62 ypaA S Protein of unknown function (DUF1304)
NCIMKDED_00033 0.0 oppA3 E ABC transporter, substratebinding protein
NCIMKDED_00034 4e-242 V ABC transporter transmembrane region
NCIMKDED_00035 2.1e-76 yybA 2.3.1.57 K Transcriptional regulator
NCIMKDED_00036 3.7e-96 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
NCIMKDED_00037 2.6e-101 S Peptidase propeptide and YPEB domain
NCIMKDED_00038 2.9e-88 S Peptidase propeptide and YPEB domain
NCIMKDED_00039 1.5e-247 T GHKL domain
NCIMKDED_00040 3.1e-130 T Transcriptional regulatory protein, C terminal
NCIMKDED_00041 2.1e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
NCIMKDED_00042 9e-279 V ABC transporter transmembrane region
NCIMKDED_00043 9.3e-130 S PAS domain
NCIMKDED_00044 1.8e-13
NCIMKDED_00045 9e-141 pnuC H nicotinamide mononucleotide transporter
NCIMKDED_00046 1.1e-72 S Protein of unknown function (DUF3290)
NCIMKDED_00047 6.7e-116 yviA S Protein of unknown function (DUF421)
NCIMKDED_00048 2.4e-158 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NCIMKDED_00049 3.2e-183 dnaQ 2.7.7.7 L EXOIII
NCIMKDED_00050 1.9e-158 endA F DNA RNA non-specific endonuclease
NCIMKDED_00051 1.8e-283 pipD E Dipeptidase
NCIMKDED_00052 1e-201 malK P ATPases associated with a variety of cellular activities
NCIMKDED_00053 1.6e-157 gtsB P ABC-type sugar transport systems, permease components
NCIMKDED_00054 6.1e-146 gtsC P Binding-protein-dependent transport system inner membrane component
NCIMKDED_00055 2.4e-258 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
NCIMKDED_00056 2.5e-239 G Bacterial extracellular solute-binding protein
NCIMKDED_00057 1.8e-154 corA P CorA-like Mg2+ transporter protein
NCIMKDED_00058 8.8e-149 3.5.2.6 V Beta-lactamase enzyme family
NCIMKDED_00059 2.3e-99 yobS K Bacterial regulatory proteins, tetR family
NCIMKDED_00060 0.0 ydgH S MMPL family
NCIMKDED_00062 1.3e-25 K Acetyltransferase (GNAT) domain
NCIMKDED_00063 1.8e-163
NCIMKDED_00064 3.3e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
NCIMKDED_00065 2.4e-92 F Nucleoside 2-deoxyribosyltransferase
NCIMKDED_00066 1.5e-158 hipB K Helix-turn-helix
NCIMKDED_00067 6.5e-153 I alpha/beta hydrolase fold
NCIMKDED_00068 1.4e-110 yjbF S SNARE associated Golgi protein
NCIMKDED_00069 8.3e-99 J Acetyltransferase (GNAT) domain
NCIMKDED_00070 1.9e-247 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NCIMKDED_00071 4.1e-10 UW LPXTG-motif cell wall anchor domain protein
NCIMKDED_00072 1.9e-39 UW LPXTG-motif cell wall anchor domain protein
NCIMKDED_00073 3e-211 UW LPXTG-motif cell wall anchor domain protein
NCIMKDED_00074 2.7e-126 UW LPXTG-motif cell wall anchor domain protein
NCIMKDED_00077 3.2e-74 K Copper transport repressor CopY TcrY
NCIMKDED_00078 0.0 copB 3.6.3.4 P P-type ATPase
NCIMKDED_00080 2.8e-42 L Type III restriction enzyme, res subunit
NCIMKDED_00082 5e-100 cadD P Cadmium resistance transporter
NCIMKDED_00083 2.4e-43 L transposase activity
NCIMKDED_00084 1.7e-213 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NCIMKDED_00085 8.7e-209 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
NCIMKDED_00086 0.0 yjbQ P TrkA C-terminal domain protein
NCIMKDED_00087 5.7e-115 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NCIMKDED_00088 2.2e-179 S Oxidoreductase family, NAD-binding Rossmann fold
NCIMKDED_00089 9.5e-144
NCIMKDED_00090 2.3e-136
NCIMKDED_00091 5e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NCIMKDED_00092 1.3e-99 G Aldose 1-epimerase
NCIMKDED_00093 2.1e-202 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NCIMKDED_00094 1.6e-111 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NCIMKDED_00095 0.0 XK27_08315 M Sulfatase
NCIMKDED_00096 1.6e-243 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NCIMKDED_00097 1.2e-53
NCIMKDED_00099 1.6e-257 pepC 3.4.22.40 E aminopeptidase
NCIMKDED_00100 2.6e-123 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NCIMKDED_00101 5e-301 oppA E ABC transporter, substratebinding protein
NCIMKDED_00102 1.7e-309 oppA E ABC transporter, substratebinding protein
NCIMKDED_00103 1.7e-210 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NCIMKDED_00104 1.1e-146 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
NCIMKDED_00105 8e-188 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
NCIMKDED_00106 2.7e-199 oppD P Belongs to the ABC transporter superfamily
NCIMKDED_00107 1.9e-175 oppF P Belongs to the ABC transporter superfamily
NCIMKDED_00108 1.4e-256 pepC 3.4.22.40 E aminopeptidase
NCIMKDED_00109 2.9e-67 hsp O Belongs to the small heat shock protein (HSP20) family
NCIMKDED_00110 2.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NCIMKDED_00111 1.2e-112
NCIMKDED_00113 1.2e-111 E Belongs to the SOS response-associated peptidase family
NCIMKDED_00114 3.7e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
NCIMKDED_00115 5.7e-88 comEB 3.5.4.12 F MafB19-like deaminase
NCIMKDED_00116 3.8e-102 S TPM domain
NCIMKDED_00117 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
NCIMKDED_00119 1.3e-112 V ABC-type multidrug transport system, ATPase and permease components
NCIMKDED_00120 8.4e-134 KLT Protein kinase domain
NCIMKDED_00121 2.4e-159 V ABC-type multidrug transport system, ATPase and permease components
NCIMKDED_00122 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NCIMKDED_00123 3e-147 tatD L hydrolase, TatD family
NCIMKDED_00124 1e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NCIMKDED_00125 2.5e-161 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NCIMKDED_00126 1.2e-39 veg S Biofilm formation stimulator VEG
NCIMKDED_00127 2.9e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
NCIMKDED_00128 8.9e-174 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NCIMKDED_00129 5.3e-80
NCIMKDED_00130 0.0 S SLAP domain
NCIMKDED_00131 6e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NCIMKDED_00132 6.7e-170 2.7.1.2 GK ROK family
NCIMKDED_00133 6.5e-44
NCIMKDED_00134 5.5e-269 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
NCIMKDED_00135 1.1e-68 S Domain of unknown function (DUF1934)
NCIMKDED_00136 4e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NCIMKDED_00137 6.7e-311 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NCIMKDED_00138 9.6e-247 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NCIMKDED_00139 8.8e-74 K acetyltransferase
NCIMKDED_00140 9.7e-285 pipD E Dipeptidase
NCIMKDED_00141 1.7e-153 msmR K AraC-like ligand binding domain
NCIMKDED_00142 1.6e-225 pbuX F xanthine permease
NCIMKDED_00143 4.5e-103 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NCIMKDED_00145 1.5e-31
NCIMKDED_00147 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NCIMKDED_00148 6.5e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NCIMKDED_00149 2.5e-104 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NCIMKDED_00150 4.6e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NCIMKDED_00151 3e-251 dnaB L Replication initiation and membrane attachment
NCIMKDED_00152 2.1e-168 dnaI L Primosomal protein DnaI
NCIMKDED_00153 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NCIMKDED_00154 5.9e-174 V Abi-like protein
NCIMKDED_00155 3.5e-91
NCIMKDED_00156 7.8e-76 K LytTr DNA-binding domain
NCIMKDED_00157 3.8e-75 S Protein of unknown function (DUF3021)
NCIMKDED_00158 8.3e-168 V ABC transporter
NCIMKDED_00159 3e-123 S domain protein
NCIMKDED_00160 7.1e-106 yyaR K Acetyltransferase (GNAT) domain
NCIMKDED_00161 2.2e-73 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NCIMKDED_00162 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NCIMKDED_00163 3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NCIMKDED_00164 1.1e-152 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NCIMKDED_00165 9.2e-201 tnpB L Putative transposase DNA-binding domain
NCIMKDED_00166 4.2e-84 yqeG S HAD phosphatase, family IIIA
NCIMKDED_00167 4.4e-200 yqeH S Ribosome biogenesis GTPase YqeH
NCIMKDED_00168 1.2e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NCIMKDED_00169 6.6e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
NCIMKDED_00170 5.3e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NCIMKDED_00171 1.2e-216 ylbM S Belongs to the UPF0348 family
NCIMKDED_00172 5.5e-98 yceD S Uncharacterized ACR, COG1399
NCIMKDED_00173 1.2e-126 K response regulator
NCIMKDED_00174 3.4e-278 arlS 2.7.13.3 T Histidine kinase
NCIMKDED_00175 1.2e-49 S CAAX protease self-immunity
NCIMKDED_00176 1e-223 S SLAP domain
NCIMKDED_00177 1.2e-85 S Aminoacyl-tRNA editing domain
NCIMKDED_00178 7.6e-164 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NCIMKDED_00179 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NCIMKDED_00180 1.9e-138 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NCIMKDED_00181 3.6e-63 yodB K Transcriptional regulator, HxlR family
NCIMKDED_00183 1.5e-110 papP P ABC transporter, permease protein
NCIMKDED_00184 2.8e-117 P ABC transporter permease
NCIMKDED_00185 9.7e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NCIMKDED_00186 2.9e-162 cjaA ET ABC transporter substrate-binding protein
NCIMKDED_00187 7.1e-200 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NCIMKDED_00188 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NCIMKDED_00189 4.9e-63 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NCIMKDED_00190 4.3e-169 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
NCIMKDED_00191 1e-156 metQ1 P Belongs to the nlpA lipoprotein family
NCIMKDED_00192 1.3e-24
NCIMKDED_00193 0.0 mco Q Multicopper oxidase
NCIMKDED_00194 1.6e-146 S Sucrose-6F-phosphate phosphohydrolase
NCIMKDED_00195 0.0 oppA E ABC transporter
NCIMKDED_00196 7.3e-233 Q Imidazolonepropionase and related amidohydrolases
NCIMKDED_00197 2.2e-219 3.5.1.47 S Peptidase dimerisation domain
NCIMKDED_00198 3.5e-138 S Protein of unknown function (DUF3100)
NCIMKDED_00199 4.4e-83 S An automated process has identified a potential problem with this gene model
NCIMKDED_00200 2.9e-50 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NCIMKDED_00201 1.2e-111 S SLAP domain
NCIMKDED_00202 2.4e-88
NCIMKDED_00203 3e-09 isdH M Iron Transport-associated domain
NCIMKDED_00204 3.7e-123 M Iron Transport-associated domain
NCIMKDED_00205 1.5e-158 isdE P Periplasmic binding protein
NCIMKDED_00206 5.6e-148 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NCIMKDED_00207 7.5e-138 fhuC 3.6.3.34 HP abc transporter atp-binding protein
NCIMKDED_00208 6.7e-44 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NCIMKDED_00209 1.2e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
NCIMKDED_00210 1.3e-38 S RelB antitoxin
NCIMKDED_00211 5.2e-170 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
NCIMKDED_00212 0.0 S membrane
NCIMKDED_00213 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
NCIMKDED_00214 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NCIMKDED_00215 2.7e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NCIMKDED_00216 4e-119 gluP 3.4.21.105 S Rhomboid family
NCIMKDED_00217 9.7e-36 yqgQ S Bacterial protein of unknown function (DUF910)
NCIMKDED_00218 1.5e-65 yqhL P Rhodanese-like protein
NCIMKDED_00219 3.5e-169 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NCIMKDED_00220 1e-224 ynbB 4.4.1.1 P aluminum resistance
NCIMKDED_00221 2e-263 glnA 6.3.1.2 E glutamine synthetase
NCIMKDED_00222 3.1e-159
NCIMKDED_00223 4.7e-145
NCIMKDED_00224 3e-57 F DNA/RNA non-specific endonuclease
NCIMKDED_00225 0.0 aha1 P E1-E2 ATPase
NCIMKDED_00226 1.5e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NCIMKDED_00227 1.5e-180 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NCIMKDED_00228 2.4e-251 yifK E Amino acid permease
NCIMKDED_00229 5e-282 V ABC-type multidrug transport system, ATPase and permease components
NCIMKDED_00230 2.4e-287 P ABC transporter
NCIMKDED_00231 1.5e-36
NCIMKDED_00233 1.4e-124 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
NCIMKDED_00234 6.5e-87 K GNAT family
NCIMKDED_00235 3.4e-205 XK27_00915 C Luciferase-like monooxygenase
NCIMKDED_00236 8.7e-117 rbtT P Major Facilitator Superfamily
NCIMKDED_00237 2.5e-08 S Protein of unknown function (DUF3021)
NCIMKDED_00238 4.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NCIMKDED_00239 0.0 L Plasmid pRiA4b ORF-3-like protein
NCIMKDED_00240 4.3e-245 brnQ U Component of the transport system for branched-chain amino acids
NCIMKDED_00241 2.4e-118 3.6.1.55 F NUDIX domain
NCIMKDED_00242 1.7e-76 ltrA S Bacterial low temperature requirement A protein (LtrA)
NCIMKDED_00243 9.6e-113 S Protein of unknown function (DUF1211)
NCIMKDED_00244 5.7e-121 lsa S ABC transporter
NCIMKDED_00245 4.2e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NCIMKDED_00246 2e-106 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
NCIMKDED_00247 2.4e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
NCIMKDED_00248 9.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NCIMKDED_00249 2.7e-31 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NCIMKDED_00250 2.2e-88 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NCIMKDED_00251 1.7e-12 L Transposase and inactivated derivatives, IS30 family
NCIMKDED_00252 2.2e-14 L Transposase and inactivated derivatives, IS30 family
NCIMKDED_00253 2.2e-68 L Transposase and inactivated derivatives, IS30 family
NCIMKDED_00254 4.1e-206 G Glycosyl hydrolases family 8
NCIMKDED_00255 8.2e-246 ydaM M Glycosyl transferase
NCIMKDED_00257 3.2e-150
NCIMKDED_00258 3.7e-54 M Peptidase family M1 domain
NCIMKDED_00259 1e-24 mepA V MATE efflux family protein
NCIMKDED_00260 1.4e-199 mepA V MATE efflux family protein
NCIMKDED_00261 1.4e-72 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
NCIMKDED_00262 2.9e-70 S Putative adhesin
NCIMKDED_00263 6.9e-107 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NCIMKDED_00264 4.7e-18 1.3.5.4 C FAD dependent oxidoreductase
NCIMKDED_00265 3.4e-85 dps P Belongs to the Dps family
NCIMKDED_00266 1.5e-178 MA20_14895 S Conserved hypothetical protein 698
NCIMKDED_00268 5.1e-192 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NCIMKDED_00269 2.2e-102 3.6.1.27 I Acid phosphatase homologues
NCIMKDED_00270 1.3e-148 yitS S Uncharacterised protein, DegV family COG1307
NCIMKDED_00271 3.4e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NCIMKDED_00272 7.5e-91 S Domain of unknown function (DUF4767)
NCIMKDED_00273 6.4e-60 C nitroreductase
NCIMKDED_00274 4.7e-08 C nitroreductase
NCIMKDED_00275 5.4e-137 ypbG 2.7.1.2 GK ROK family
NCIMKDED_00276 5.2e-275 bglA3 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NCIMKDED_00277 3.7e-223 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NCIMKDED_00278 1.9e-119 gmuR K UTRA
NCIMKDED_00279 5.5e-299 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NCIMKDED_00280 3.2e-71 S Domain of unknown function (DUF3284)
NCIMKDED_00281 8.7e-60 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
NCIMKDED_00282 1.6e-55 celA1 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
NCIMKDED_00283 1.4e-127 K UTRA domain
NCIMKDED_00284 4e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NCIMKDED_00285 2.2e-90 alkD L DNA alkylation repair enzyme
NCIMKDED_00286 1.3e-176 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
NCIMKDED_00287 1.9e-81
NCIMKDED_00288 8.8e-38 C FMN_bind
NCIMKDED_00289 7.1e-300 I Protein of unknown function (DUF2974)
NCIMKDED_00290 5e-196 pbpX1 V Beta-lactamase
NCIMKDED_00291 7.9e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NCIMKDED_00292 3.8e-218 aspC 2.6.1.1 E Aminotransferase
NCIMKDED_00293 1.2e-143 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NCIMKDED_00294 1.4e-175 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NCIMKDED_00295 1.1e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NCIMKDED_00296 9.7e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NCIMKDED_00297 2.6e-247 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NCIMKDED_00298 1.1e-178 lysC 2.7.2.4 E Belongs to the aspartokinase family
NCIMKDED_00299 2.7e-123 yoaK S Protein of unknown function (DUF1275)
NCIMKDED_00300 5.7e-230 L Transposase
NCIMKDED_00301 4e-57 K Helix-turn-helix domain
NCIMKDED_00302 1.1e-112 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NCIMKDED_00303 7.3e-172 ppaC 3.6.1.1 C inorganic pyrophosphatase
NCIMKDED_00304 4.8e-182 K Transcriptional regulator
NCIMKDED_00305 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NCIMKDED_00306 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NCIMKDED_00307 3.5e-109 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NCIMKDED_00308 3.3e-158 snf 2.7.11.1 KL domain protein
NCIMKDED_00309 0.0 snf 2.7.11.1 KL domain protein
NCIMKDED_00311 4.3e-36
NCIMKDED_00312 1e-104 pncA Q Isochorismatase family
NCIMKDED_00313 1.3e-118
NCIMKDED_00316 3.6e-63
NCIMKDED_00317 1.4e-34
NCIMKDED_00318 1.9e-115 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
NCIMKDED_00319 3.4e-79
NCIMKDED_00320 1e-242 cpdA S Calcineurin-like phosphoesterase
NCIMKDED_00321 9.6e-219 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NCIMKDED_00322 1.1e-68 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NCIMKDED_00323 1e-107 ypsA S Belongs to the UPF0398 family
NCIMKDED_00324 4.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NCIMKDED_00325 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
NCIMKDED_00326 6.1e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NCIMKDED_00327 1.3e-114 dnaD L DnaD domain protein
NCIMKDED_00328 5.8e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
NCIMKDED_00329 8.3e-90 ypmB S Protein conserved in bacteria
NCIMKDED_00330 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NCIMKDED_00331 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NCIMKDED_00332 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NCIMKDED_00333 1.3e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
NCIMKDED_00334 1.4e-178 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NCIMKDED_00335 4.6e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
NCIMKDED_00336 8.2e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NCIMKDED_00337 1.3e-116 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
NCIMKDED_00338 1.7e-265 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
NCIMKDED_00339 1.1e-167
NCIMKDED_00340 1.8e-144
NCIMKDED_00341 2.5e-103 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NCIMKDED_00342 3.8e-27
NCIMKDED_00343 5.6e-144
NCIMKDED_00344 8.6e-137
NCIMKDED_00345 1.1e-142
NCIMKDED_00346 9.6e-124 skfE V ATPases associated with a variety of cellular activities
NCIMKDED_00347 1.6e-61 yvoA_1 K Transcriptional regulator, GntR family
NCIMKDED_00348 2.2e-240 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NCIMKDED_00349 5e-153 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NCIMKDED_00350 2.4e-124 trmK 2.1.1.217 S SAM-dependent methyltransferase
NCIMKDED_00351 4.8e-81 mutT 3.6.1.55 F NUDIX domain
NCIMKDED_00352 2.3e-127 S Peptidase family M23
NCIMKDED_00353 9.9e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NCIMKDED_00354 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NCIMKDED_00355 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NCIMKDED_00356 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NCIMKDED_00357 1.1e-128 recO L Involved in DNA repair and RecF pathway recombination
NCIMKDED_00358 2.4e-181 L transposase, IS605 OrfB family
NCIMKDED_00359 5.9e-140 noxC 1.5.1.39 C coenzyme F420-1:gamma-L-glutamate ligase activity
NCIMKDED_00360 4.9e-216 EGP Major Facilitator Superfamily
NCIMKDED_00361 3.7e-31 S ATP diphosphatase activity
NCIMKDED_00363 9.7e-60
NCIMKDED_00364 1.5e-20
NCIMKDED_00365 2.9e-148 K Helix-turn-helix domain
NCIMKDED_00366 1.5e-126 S Alpha/beta hydrolase family
NCIMKDED_00367 2.9e-156 epsV 2.7.8.12 S glycosyl transferase family 2
NCIMKDED_00368 4.4e-140 ypuA S Protein of unknown function (DUF1002)
NCIMKDED_00369 8.8e-147 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NCIMKDED_00370 7.7e-182 S Alpha/beta hydrolase of unknown function (DUF915)
NCIMKDED_00371 2.5e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NCIMKDED_00372 4.2e-86
NCIMKDED_00373 3.8e-133 cobB K SIR2 family
NCIMKDED_00374 3.2e-92 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
NCIMKDED_00375 9.6e-125 terC P Integral membrane protein TerC family
NCIMKDED_00376 2e-64 yeaO S Protein of unknown function, DUF488
NCIMKDED_00377 4.4e-120 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NCIMKDED_00378 1.3e-290 glnP P ABC transporter permease
NCIMKDED_00379 2.1e-137 glnQ E ABC transporter, ATP-binding protein
NCIMKDED_00380 3.1e-86 S Protein of unknown function (DUF805)
NCIMKDED_00381 3.5e-149 L HNH nucleases
NCIMKDED_00382 1e-119 yfbR S HD containing hydrolase-like enzyme
NCIMKDED_00383 5.7e-162 G Glycosyl hydrolases family 8
NCIMKDED_00384 1.9e-27 ydaM M Glycosyl transferase
NCIMKDED_00385 4.8e-164 ydaM M Glycosyl transferase
NCIMKDED_00387 4e-116
NCIMKDED_00388 1.2e-17
NCIMKDED_00389 2.1e-308 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
NCIMKDED_00390 2.7e-70 S Iron-sulphur cluster biosynthesis
NCIMKDED_00391 3.9e-196 ybiR P Citrate transporter
NCIMKDED_00392 3.5e-97 lemA S LemA family
NCIMKDED_00393 9.8e-158 htpX O Belongs to the peptidase M48B family
NCIMKDED_00394 2.3e-173 K helix_turn_helix, arabinose operon control protein
NCIMKDED_00395 1.1e-248 cbiO1 S ABC transporter, ATP-binding protein
NCIMKDED_00396 1.5e-75 P Cobalt transport protein
NCIMKDED_00397 6e-176 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
NCIMKDED_00398 5.5e-103 G Peptidase_C39 like family
NCIMKDED_00399 1e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NCIMKDED_00400 3.3e-151 htrA 3.4.21.107 O serine protease
NCIMKDED_00401 6.3e-148 vicX 3.1.26.11 S domain protein
NCIMKDED_00402 2.9e-148 yycI S YycH protein
NCIMKDED_00403 1.5e-258 yycH S YycH protein
NCIMKDED_00404 2.2e-305 vicK 2.7.13.3 T Histidine kinase
NCIMKDED_00405 4.8e-131 K response regulator
NCIMKDED_00407 4.9e-34
NCIMKDED_00409 1.4e-149 arbV 2.3.1.51 I Acyl-transferase
NCIMKDED_00410 1.2e-157 arbx M Glycosyl transferase family 8
NCIMKDED_00411 4.5e-185 arbY M Glycosyl transferase family 8
NCIMKDED_00412 6e-182 arbY M Glycosyl transferase family 8
NCIMKDED_00413 4.6e-168 arbZ I Phosphate acyltransferases
NCIMKDED_00414 1.4e-36 S Cytochrome B5
NCIMKDED_00415 9.5e-82 XK27_04435 3.5.4.5 J FR47-like protein
NCIMKDED_00418 7.8e-73
NCIMKDED_00420 1.2e-85 K DNA-templated transcription, initiation
NCIMKDED_00421 1.5e-25
NCIMKDED_00422 3e-56 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NCIMKDED_00423 2.7e-189 S SLAP domain
NCIMKDED_00424 1.1e-40 S Protein of unknown function (DUF2922)
NCIMKDED_00425 1.9e-27
NCIMKDED_00427 4.5e-45
NCIMKDED_00428 3.3e-59 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
NCIMKDED_00429 2.3e-10 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NCIMKDED_00430 2.1e-45 S PFAM Archaeal ATPase
NCIMKDED_00431 8.6e-75
NCIMKDED_00432 0.0 kup P Transport of potassium into the cell
NCIMKDED_00433 0.0 pepO 3.4.24.71 O Peptidase family M13
NCIMKDED_00434 1.6e-211 yttB EGP Major facilitator Superfamily
NCIMKDED_00435 1.5e-230 XK27_04775 S PAS domain
NCIMKDED_00436 2.1e-103 S Iron-sulfur cluster assembly protein
NCIMKDED_00437 8.7e-141 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NCIMKDED_00438 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NCIMKDED_00439 5.6e-255 yxbA 6.3.1.12 S ATP-grasp enzyme
NCIMKDED_00440 0.0 asnB 6.3.5.4 E Asparagine synthase
NCIMKDED_00441 1.5e-274 S Calcineurin-like phosphoesterase
NCIMKDED_00442 1.5e-83
NCIMKDED_00443 2.1e-105 tag 3.2.2.20 L glycosylase
NCIMKDED_00444 2.2e-148 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
NCIMKDED_00445 8.8e-118 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
NCIMKDED_00446 4.1e-136 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NCIMKDED_00447 4.1e-151 phnD P Phosphonate ABC transporter
NCIMKDED_00448 5.2e-84 uspA T universal stress protein
NCIMKDED_00449 1.7e-148 ptp3 3.1.3.48 T Tyrosine phosphatase family
NCIMKDED_00450 5.9e-88 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NCIMKDED_00451 1.4e-89 ntd 2.4.2.6 F Nucleoside
NCIMKDED_00452 2.3e-08
NCIMKDED_00453 4.5e-274 S Archaea bacterial proteins of unknown function
NCIMKDED_00454 1.5e-61 S Bacterial toxin of type II toxin-antitoxin system, YafQ
NCIMKDED_00455 9.8e-46
NCIMKDED_00457 2.6e-31 S Bacteriophage abortive infection AbiH
NCIMKDED_00459 2.1e-23 O Preprotein translocase subunit SecB
NCIMKDED_00461 4e-30
NCIMKDED_00462 5.6e-186 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
NCIMKDED_00463 1.7e-129 manY G PTS system
NCIMKDED_00464 1e-173 manN G system, mannose fructose sorbose family IID component
NCIMKDED_00465 9.9e-64 manO S Domain of unknown function (DUF956)
NCIMKDED_00466 3e-159 K Transcriptional regulator
NCIMKDED_00467 1.4e-90 maa S transferase hexapeptide repeat
NCIMKDED_00468 2.5e-245 cycA E Amino acid permease
NCIMKDED_00469 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NCIMKDED_00470 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NCIMKDED_00471 6.7e-09 ackA 2.7.2.1 F acetate kinase activity
NCIMKDED_00472 2.8e-167 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NCIMKDED_00473 1.6e-32
NCIMKDED_00474 1.8e-66 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
NCIMKDED_00475 2.3e-156 K Helix-turn-helix XRE-family like proteins
NCIMKDED_00476 1.3e-09 KLT Protein kinase domain
NCIMKDED_00477 3.9e-298 V ABC transporter transmembrane region
NCIMKDED_00478 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
NCIMKDED_00479 0.0 S TerB-C domain
NCIMKDED_00480 2.4e-253 P P-loop Domain of unknown function (DUF2791)
NCIMKDED_00481 0.0 lhr L DEAD DEAH box helicase
NCIMKDED_00482 1.9e-59
NCIMKDED_00483 7.3e-138 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NCIMKDED_00485 1e-61 psiE S Phosphate-starvation-inducible E
NCIMKDED_00486 3.8e-113 yncA 2.3.1.79 S Maltose acetyltransferase
NCIMKDED_00487 1.5e-70 S Iron-sulphur cluster biosynthesis
NCIMKDED_00489 4.6e-31
NCIMKDED_00490 1.1e-172 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
NCIMKDED_00491 6.2e-12
NCIMKDED_00492 1.1e-115 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NCIMKDED_00493 1.1e-28 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NCIMKDED_00494 6.8e-79 M LysM domain protein
NCIMKDED_00495 1.2e-159 D nuclear chromosome segregation
NCIMKDED_00496 1.2e-105 G Phosphoglycerate mutase family
NCIMKDED_00497 2.2e-88 G Histidine phosphatase superfamily (branch 1)
NCIMKDED_00498 1.1e-113 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
NCIMKDED_00499 1.9e-113 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NCIMKDED_00501 1.4e-284 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NCIMKDED_00502 2.3e-195 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NCIMKDED_00503 9.7e-166 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NCIMKDED_00504 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NCIMKDED_00505 4.5e-241 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NCIMKDED_00506 6.3e-63 yabR J S1 RNA binding domain
NCIMKDED_00507 6.8e-60 divIC D Septum formation initiator
NCIMKDED_00508 1.6e-33 yabO J S4 domain protein
NCIMKDED_00509 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NCIMKDED_00510 5.1e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NCIMKDED_00511 1.5e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NCIMKDED_00512 3.4e-129 S (CBS) domain
NCIMKDED_00513 1e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NCIMKDED_00514 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NCIMKDED_00515 1.9e-251 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NCIMKDED_00516 1.3e-262 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NCIMKDED_00517 2.5e-39 rpmE2 J Ribosomal protein L31
NCIMKDED_00518 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
NCIMKDED_00519 2.9e-156 S Sucrose-6F-phosphate phosphohydrolase
NCIMKDED_00520 7.8e-299 ybeC E amino acid
NCIMKDED_00521 7.5e-233 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NCIMKDED_00522 2.1e-42
NCIMKDED_00523 2.8e-52
NCIMKDED_00524 3.3e-186 5.3.3.2 C FMN-dependent dehydrogenase
NCIMKDED_00525 1.5e-145 yfeO P Voltage gated chloride channel
NCIMKDED_00526 4e-95
NCIMKDED_00527 3.3e-94 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NCIMKDED_00528 9.4e-197 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
NCIMKDED_00529 2.3e-59 hxlR K Transcriptional regulator, HxlR family
NCIMKDED_00530 2.2e-19 yjdF S Protein of unknown function (DUF2992)
NCIMKDED_00531 7.9e-57 ps115 K Helix-turn-helix XRE-family like proteins
NCIMKDED_00534 3.8e-117 L transposase, IS605 OrfB family
NCIMKDED_00535 5.4e-128 liaI S membrane
NCIMKDED_00536 3e-78 XK27_02470 K LytTr DNA-binding domain
NCIMKDED_00537 7.3e-19 S Sugar efflux transporter for intercellular exchange
NCIMKDED_00538 9.7e-251 dtpT U amino acid peptide transporter
NCIMKDED_00539 0.0 pepN 3.4.11.2 E aminopeptidase
NCIMKDED_00540 2.8e-47 lysM M LysM domain
NCIMKDED_00541 5.1e-176
NCIMKDED_00542 3.1e-210 mdtG EGP Major facilitator Superfamily
NCIMKDED_00543 1.8e-87 ymdB S Macro domain protein
NCIMKDED_00545 2.3e-09
NCIMKDED_00546 1.6e-23
NCIMKDED_00548 1.6e-66 K Helix-turn-helix XRE-family like proteins
NCIMKDED_00549 9.7e-147 malG P ABC transporter permease
NCIMKDED_00550 1.4e-248 malF P Binding-protein-dependent transport system inner membrane component
NCIMKDED_00551 2.3e-213 malE G Bacterial extracellular solute-binding protein
NCIMKDED_00552 4.7e-210 msmX P Belongs to the ABC transporter superfamily
NCIMKDED_00553 1.4e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
NCIMKDED_00554 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
NCIMKDED_00555 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
NCIMKDED_00556 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
NCIMKDED_00557 9.1e-77 S PAS domain
NCIMKDED_00558 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NCIMKDED_00559 2.4e-178 yvdE K helix_turn _helix lactose operon repressor
NCIMKDED_00560 6.3e-145 ptp2 3.1.3.48 T Tyrosine phosphatase family
NCIMKDED_00561 3.5e-293 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NCIMKDED_00562 9.6e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NCIMKDED_00563 1.7e-88
NCIMKDED_00564 3.3e-20
NCIMKDED_00565 2.4e-136 K Helix-turn-helix XRE-family like proteins
NCIMKDED_00567 2.6e-161 V ABC transporter transmembrane region
NCIMKDED_00568 2e-216 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NCIMKDED_00569 3.1e-87 gtcA S Teichoic acid glycosylation protein
NCIMKDED_00570 4.1e-80 fld C Flavodoxin
NCIMKDED_00571 6.5e-164 map 3.4.11.18 E Methionine Aminopeptidase
NCIMKDED_00572 3.6e-163 yihY S Belongs to the UPF0761 family
NCIMKDED_00573 7.3e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NCIMKDED_00574 2.3e-215 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
NCIMKDED_00575 4.5e-214 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
NCIMKDED_00576 1.9e-217 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
NCIMKDED_00577 5.1e-270 L COG2963 Transposase and inactivated derivatives
NCIMKDED_00578 9.4e-46
NCIMKDED_00579 2.6e-177 D Alpha beta
NCIMKDED_00580 2.3e-262 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NCIMKDED_00581 8.6e-145 recX 2.4.1.337 GT4 S Regulatory protein RecX
NCIMKDED_00582 1.6e-85
NCIMKDED_00583 1.6e-74
NCIMKDED_00584 1.1e-140 hlyX S Transporter associated domain
NCIMKDED_00585 3.6e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NCIMKDED_00586 2.4e-147
NCIMKDED_00587 1.6e-264 V ABC transporter transmembrane region
NCIMKDED_00590 3.6e-14
NCIMKDED_00594 2.1e-10 sagD S ATP diphosphatase activity
NCIMKDED_00595 3.4e-24
NCIMKDED_00596 2.3e-51 L Transposase
NCIMKDED_00597 3.5e-31
NCIMKDED_00598 2.3e-44 XK27_09445 S Domain of unknown function (DUF1827)
NCIMKDED_00599 0.0 clpE O Belongs to the ClpA ClpB family
NCIMKDED_00600 5.3e-26
NCIMKDED_00601 8.5e-41 ptsH G phosphocarrier protein HPR
NCIMKDED_00602 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NCIMKDED_00603 6.1e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NCIMKDED_00604 8.5e-139 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NCIMKDED_00605 5.8e-160 coiA 3.6.4.12 S Competence protein
NCIMKDED_00606 1.2e-114 yjbH Q Thioredoxin
NCIMKDED_00607 3.6e-111 yjbK S CYTH
NCIMKDED_00608 1.2e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
NCIMKDED_00609 3.8e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NCIMKDED_00610 1.2e-171 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NCIMKDED_00611 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
NCIMKDED_00612 2.5e-92 S SNARE associated Golgi protein
NCIMKDED_00613 8.2e-201 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
NCIMKDED_00614 2.4e-65 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
NCIMKDED_00615 2.6e-214 yubA S AI-2E family transporter
NCIMKDED_00616 4.2e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NCIMKDED_00617 1.7e-69 WQ51_03320 S Protein of unknown function (DUF1149)
NCIMKDED_00618 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NCIMKDED_00619 2.6e-222 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
NCIMKDED_00620 3.9e-237 S Peptidase M16
NCIMKDED_00621 1.4e-133 IQ Enoyl-(Acyl carrier protein) reductase
NCIMKDED_00622 2.2e-95 ymfM S Helix-turn-helix domain
NCIMKDED_00623 1.1e-95 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NCIMKDED_00624 2.5e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NCIMKDED_00625 4.3e-220 rny S Endoribonuclease that initiates mRNA decay
NCIMKDED_00626 1.3e-210 tagO 2.7.8.33, 2.7.8.35 M transferase
NCIMKDED_00627 5.1e-119 yvyE 3.4.13.9 S YigZ family
NCIMKDED_00628 1.2e-244 comFA L Helicase C-terminal domain protein
NCIMKDED_00629 2.2e-133 comFC S Competence protein
NCIMKDED_00630 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NCIMKDED_00631 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NCIMKDED_00632 1.3e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NCIMKDED_00633 5.1e-17
NCIMKDED_00634 5.8e-180 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NCIMKDED_00635 4.1e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NCIMKDED_00636 3.3e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NCIMKDED_00637 3.9e-181 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NCIMKDED_00638 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NCIMKDED_00639 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NCIMKDED_00640 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NCIMKDED_00641 1.1e-90 S Short repeat of unknown function (DUF308)
NCIMKDED_00642 3.1e-164 rapZ S Displays ATPase and GTPase activities
NCIMKDED_00643 1.1e-195 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NCIMKDED_00644 2.1e-171 whiA K May be required for sporulation
NCIMKDED_00645 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NCIMKDED_00646 0.0 S SH3-like domain
NCIMKDED_00647 4.9e-111 ybbL S ABC transporter, ATP-binding protein
NCIMKDED_00648 8.7e-131 ybbM S Uncharacterised protein family (UPF0014)
NCIMKDED_00649 8.7e-96 S Domain of unknown function (DUF4811)
NCIMKDED_00650 6.4e-263 lmrB EGP Major facilitator Superfamily
NCIMKDED_00651 1.4e-77 K MerR HTH family regulatory protein
NCIMKDED_00652 5.4e-144 S Cysteine-rich secretory protein family
NCIMKDED_00653 9.2e-275 ycaM E amino acid
NCIMKDED_00654 9.8e-291
NCIMKDED_00656 1.5e-189 cggR K Putative sugar-binding domain
NCIMKDED_00657 6.5e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NCIMKDED_00658 1e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NCIMKDED_00659 1.7e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NCIMKDED_00660 1.3e-93
NCIMKDED_00661 1.8e-156 ycsE S Sucrose-6F-phosphate phosphohydrolase
NCIMKDED_00662 9.7e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NCIMKDED_00663 6.3e-182 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NCIMKDED_00664 1.4e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
NCIMKDED_00665 4e-98 dnaQ 2.7.7.7 L DNA polymerase III
NCIMKDED_00666 1.8e-164 murB 1.3.1.98 M Cell wall formation
NCIMKDED_00667 1.8e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NCIMKDED_00668 5.4e-131 potB P ABC transporter permease
NCIMKDED_00669 2.1e-127 potC P ABC transporter permease
NCIMKDED_00670 7.3e-208 potD P ABC transporter
NCIMKDED_00671 6.4e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NCIMKDED_00672 2e-172 ybbR S YbbR-like protein
NCIMKDED_00673 2.4e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NCIMKDED_00674 3.8e-148 S hydrolase
NCIMKDED_00675 1.8e-75 K Penicillinase repressor
NCIMKDED_00676 9.4e-119
NCIMKDED_00677 1.6e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NCIMKDED_00678 1.8e-209 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NCIMKDED_00679 5.4e-142 licT K CAT RNA binding domain
NCIMKDED_00680 0.0 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
NCIMKDED_00681 1.7e-300 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NCIMKDED_00682 5.5e-175 D Alpha beta
NCIMKDED_00683 2.5e-305 E Amino acid permease
NCIMKDED_00685 9.8e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NCIMKDED_00686 9.7e-112 ylbE GM NAD(P)H-binding
NCIMKDED_00687 2.9e-93 S VanZ like family
NCIMKDED_00688 8.9e-133 yebC K Transcriptional regulatory protein
NCIMKDED_00689 2.9e-179 comGA NU Type II IV secretion system protein
NCIMKDED_00690 2.7e-172 comGB NU type II secretion system
NCIMKDED_00691 3.1e-43 comGC U competence protein ComGC
NCIMKDED_00692 7.4e-71
NCIMKDED_00693 2.3e-41
NCIMKDED_00694 7.2e-76 comGF U Putative Competence protein ComGF
NCIMKDED_00695 2.3e-20
NCIMKDED_00696 3.5e-188 ytxK 2.1.1.72 L N-6 DNA Methylase
NCIMKDED_00697 9.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NCIMKDED_00699 3.7e-32 M Protein of unknown function (DUF3737)
NCIMKDED_00700 4.5e-52 M Protein of unknown function (DUF3737)
NCIMKDED_00701 7.1e-225 patB 4.4.1.8 E Aminotransferase, class I
NCIMKDED_00702 6.5e-192 manA 5.3.1.8 G mannose-6-phosphate isomerase
NCIMKDED_00703 7.7e-67 S SdpI/YhfL protein family
NCIMKDED_00704 2e-129 K Transcriptional regulatory protein, C terminal
NCIMKDED_00705 1.9e-267 yclK 2.7.13.3, 4.6.1.1 T Histidine kinase
NCIMKDED_00706 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NCIMKDED_00707 3.8e-105 vanZ V VanZ like family
NCIMKDED_00708 2.2e-254 pgi 5.3.1.9 G Belongs to the GPI family
NCIMKDED_00709 5.8e-218 EGP Major facilitator Superfamily
NCIMKDED_00710 8.7e-195 ampC V Beta-lactamase
NCIMKDED_00713 5.8e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
NCIMKDED_00714 1.4e-112 tdk 2.7.1.21 F thymidine kinase
NCIMKDED_00715 6.9e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NCIMKDED_00716 2.5e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NCIMKDED_00717 1.1e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NCIMKDED_00718 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NCIMKDED_00719 5.1e-125 atpB C it plays a direct role in the translocation of protons across the membrane
NCIMKDED_00720 3.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NCIMKDED_00721 3.4e-46 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NCIMKDED_00722 5.4e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NCIMKDED_00723 2.5e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NCIMKDED_00724 8.9e-173 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NCIMKDED_00725 3.3e-240 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NCIMKDED_00726 9e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NCIMKDED_00727 6.9e-31 ywzB S Protein of unknown function (DUF1146)
NCIMKDED_00728 2.5e-178 mbl D Cell shape determining protein MreB Mrl
NCIMKDED_00729 2.6e-51 yidD S Could be involved in insertion of integral membrane proteins into the membrane
NCIMKDED_00730 1.5e-33 S Protein of unknown function (DUF2969)
NCIMKDED_00731 1.2e-216 rodA D Belongs to the SEDS family
NCIMKDED_00732 2.3e-78 usp6 T universal stress protein
NCIMKDED_00733 8.4e-39
NCIMKDED_00734 1.1e-237 rarA L recombination factor protein RarA
NCIMKDED_00735 9.9e-85 yueI S Protein of unknown function (DUF1694)
NCIMKDED_00736 1.4e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NCIMKDED_00737 1.1e-293 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NCIMKDED_00738 1.8e-215 iscS2 2.8.1.7 E Aminotransferase class V
NCIMKDED_00739 6.3e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NCIMKDED_00741 1.2e-82 K Helix-turn-helix XRE-family like proteins
NCIMKDED_00742 1.7e-61
NCIMKDED_00743 5.7e-33 gepA S Protein of unknown function (DUF4065)
NCIMKDED_00744 4e-35
NCIMKDED_00748 4.7e-111
NCIMKDED_00749 1.8e-134 K Helix-turn-helix XRE-family like proteins
NCIMKDED_00750 1.7e-111
NCIMKDED_00752 1.5e-121 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NCIMKDED_00753 2.8e-149 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NCIMKDED_00754 2.9e-67 2.4.1.83 GT2 S GtrA-like protein
NCIMKDED_00755 1.2e-171 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
NCIMKDED_00756 3.7e-93 S Protein of unknown function (DUF3990)
NCIMKDED_00757 6.5e-44
NCIMKDED_00759 0.0 3.6.3.8 P P-type ATPase
NCIMKDED_00760 3e-165
NCIMKDED_00761 3.9e-136 K Helix-turn-helix domain
NCIMKDED_00762 1.4e-62 S Phage derived protein Gp49-like (DUF891)
NCIMKDED_00763 2.7e-42 K Helix-turn-helix XRE-family like proteins
NCIMKDED_00764 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NCIMKDED_00765 1e-240 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NCIMKDED_00766 2.8e-125 S Haloacid dehalogenase-like hydrolase
NCIMKDED_00767 2.3e-108 radC L DNA repair protein
NCIMKDED_00768 1.8e-176 mreB D cell shape determining protein MreB
NCIMKDED_00769 8.8e-148 mreC M Involved in formation and maintenance of cell shape
NCIMKDED_00770 2.7e-94 mreD
NCIMKDED_00772 6.4e-54 S Protein of unknown function (DUF3397)
NCIMKDED_00773 6.3e-78 mraZ K Belongs to the MraZ family
NCIMKDED_00774 3.8e-176 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NCIMKDED_00775 1.8e-54 ftsL D Cell division protein FtsL
NCIMKDED_00776 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NCIMKDED_00777 1.1e-175 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NCIMKDED_00778 9.5e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NCIMKDED_00779 4.4e-208 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NCIMKDED_00780 4.1e-153 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NCIMKDED_00781 2.6e-247 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NCIMKDED_00782 1.8e-219 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NCIMKDED_00783 7.3e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NCIMKDED_00784 2.2e-45 yggT S YGGT family
NCIMKDED_00785 6.7e-150 ylmH S S4 domain protein
NCIMKDED_00786 2.8e-74 gpsB D DivIVA domain protein
NCIMKDED_00787 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NCIMKDED_00788 3.6e-31 cspA K 'Cold-shock' DNA-binding domain
NCIMKDED_00789 9.8e-103 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
NCIMKDED_00790 2.1e-38
NCIMKDED_00791 4.5e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NCIMKDED_00792 7.1e-217 iscS 2.8.1.7 E Aminotransferase class V
NCIMKDED_00793 2.2e-57 XK27_04120 S Putative amino acid metabolism
NCIMKDED_00794 4.6e-221 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NCIMKDED_00795 3.9e-127 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
NCIMKDED_00796 2.4e-105 S Repeat protein
NCIMKDED_00797 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NCIMKDED_00798 5.4e-295 L Nuclease-related domain
NCIMKDED_00799 4.7e-182 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
NCIMKDED_00800 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NCIMKDED_00801 3.2e-33 ykzG S Belongs to the UPF0356 family
NCIMKDED_00802 3.4e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NCIMKDED_00803 0.0 typA T GTP-binding protein TypA
NCIMKDED_00804 1.2e-211 ftsW D Belongs to the SEDS family
NCIMKDED_00805 5.1e-54 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
NCIMKDED_00806 1.7e-96 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
NCIMKDED_00807 3.6e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NCIMKDED_00808 5.6e-189 ylbL T Belongs to the peptidase S16 family
NCIMKDED_00809 4.1e-79 comEA L Competence protein ComEA
NCIMKDED_00810 0.0 comEC S Competence protein ComEC
NCIMKDED_00811 2.6e-175 holA 2.7.7.7 L DNA polymerase III delta subunit
NCIMKDED_00812 6.7e-35 rpsT J Binds directly to 16S ribosomal RNA
NCIMKDED_00813 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NCIMKDED_00814 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NCIMKDED_00815 8.3e-151
NCIMKDED_00816 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NCIMKDED_00817 4e-216 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NCIMKDED_00818 4.5e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NCIMKDED_00819 3.7e-105 engB D Necessary for normal cell division and for the maintenance of normal septation
NCIMKDED_00820 4.1e-21 yjeM E Amino Acid
NCIMKDED_00821 1.5e-135 yjeM E Amino Acid
NCIMKDED_00822 1.5e-191 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NCIMKDED_00823 4.4e-55 lysC 2.7.2.4 E Belongs to the aspartokinase family
NCIMKDED_00828 5.4e-78 S response to antibiotic
NCIMKDED_00829 8.9e-34
NCIMKDED_00830 2.1e-38
NCIMKDED_00831 1.7e-32
NCIMKDED_00832 1.7e-25
NCIMKDED_00833 1.5e-21
NCIMKDED_00834 2.1e-61 K Helix-turn-helix XRE-family like proteins
NCIMKDED_00835 3.2e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NCIMKDED_00836 0.0 G Belongs to the glycosyl hydrolase 31 family
NCIMKDED_00837 5.9e-149 I alpha/beta hydrolase fold
NCIMKDED_00838 3.4e-130 yibF S overlaps another CDS with the same product name
NCIMKDED_00839 1.1e-201 yibE S overlaps another CDS with the same product name
NCIMKDED_00840 3.1e-112
NCIMKDED_00841 5.3e-206 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NCIMKDED_00842 6.4e-224 S Cysteine-rich secretory protein family
NCIMKDED_00843 9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NCIMKDED_00844 1.2e-217 glnPH2 P ABC transporter permease
NCIMKDED_00845 1.6e-32 glnPH2 P ABC transporter permease
NCIMKDED_00846 2.8e-135
NCIMKDED_00847 2.4e-124 luxT K Bacterial regulatory proteins, tetR family
NCIMKDED_00848 2.6e-183 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NCIMKDED_00850 3.6e-82
NCIMKDED_00851 1.4e-18
NCIMKDED_00852 4.1e-262 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NCIMKDED_00853 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NCIMKDED_00854 3.4e-274 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NCIMKDED_00855 6.7e-287 clcA P chloride
NCIMKDED_00856 4e-32 E Zn peptidase
NCIMKDED_00857 3.7e-58 ps115 K Helix-turn-helix XRE-family like proteins
NCIMKDED_00858 5.5e-60 L An automated process has identified a potential problem with this gene model
NCIMKDED_00859 3.3e-78 L An automated process has identified a potential problem with this gene model
NCIMKDED_00860 1.4e-240 yisQ V MatE
NCIMKDED_00861 3.5e-199 V MatE
NCIMKDED_00862 5.3e-130 GK ROK family
NCIMKDED_00863 1.7e-42 rhaS6 K helix_turn_helix, arabinose operon control protein
NCIMKDED_00864 1.1e-82 L An automated process has identified a potential problem with this gene model
NCIMKDED_00865 6.6e-212
NCIMKDED_00866 1.2e-18
NCIMKDED_00867 1e-246 EGP Sugar (and other) transporter
NCIMKDED_00868 1.2e-105
NCIMKDED_00869 2.4e-113 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
NCIMKDED_00870 0.0 copA 3.6.3.54 P P-type ATPase
NCIMKDED_00871 7e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NCIMKDED_00872 2.7e-64 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NCIMKDED_00873 5.7e-74 atkY K Penicillinase repressor
NCIMKDED_00874 2.3e-72 S Putative adhesin
NCIMKDED_00875 9.6e-56 K Helix-turn-helix domain
NCIMKDED_00876 1.8e-27
NCIMKDED_00877 9.4e-226 pbuG S permease
NCIMKDED_00879 9.8e-121 yhiD S MgtC family
NCIMKDED_00880 1.6e-230 I Protein of unknown function (DUF2974)
NCIMKDED_00881 3.5e-15 S Transglycosylase associated protein
NCIMKDED_00883 1.2e-168 scrK 2.7.1.2, 2.7.1.4 GK ROK family
NCIMKDED_00884 4.6e-166 degV S DegV family
NCIMKDED_00885 3.5e-166 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
NCIMKDED_00886 6.7e-254 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NCIMKDED_00887 5.7e-69 rplI J Binds to the 23S rRNA
NCIMKDED_00888 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NCIMKDED_00889 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NCIMKDED_00890 4.5e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NCIMKDED_00891 9.4e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
NCIMKDED_00892 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NCIMKDED_00893 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NCIMKDED_00894 6.2e-210 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NCIMKDED_00895 2.6e-35 yaaA S S4 domain protein YaaA
NCIMKDED_00896 1.1e-185 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NCIMKDED_00897 5.5e-245 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NCIMKDED_00898 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
NCIMKDED_00899 2.7e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NCIMKDED_00900 8.4e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NCIMKDED_00902 1.7e-218 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
NCIMKDED_00903 1.7e-187 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
NCIMKDED_00904 9.6e-121 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
NCIMKDED_00905 1.3e-143 K SIS domain
NCIMKDED_00906 8.4e-87 S SLAP domain
NCIMKDED_00909 4.4e-242 npr 1.11.1.1 C NADH oxidase
NCIMKDED_00912 1.6e-299 oppA2 E ABC transporter, substratebinding protein
NCIMKDED_00913 1.1e-179
NCIMKDED_00914 1.3e-125 gntR1 K UTRA
NCIMKDED_00915 5.1e-71 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
NCIMKDED_00916 4.3e-135 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NCIMKDED_00917 2e-205 csaB M Glycosyl transferases group 1
NCIMKDED_00918 2.4e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NCIMKDED_00919 4e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NCIMKDED_00920 0.0 pacL 3.6.3.8 P P-type ATPase
NCIMKDED_00921 7e-225 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NCIMKDED_00922 6.4e-260 epsU S Polysaccharide biosynthesis protein
NCIMKDED_00923 3.8e-37 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 S regulation of response to stimulus
NCIMKDED_00924 1.1e-117 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NCIMKDED_00925 0.0 oppA E ABC transporter substrate-binding protein
NCIMKDED_00926 3.2e-176 K AI-2E family transporter
NCIMKDED_00927 6.8e-104 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
NCIMKDED_00928 6.9e-18
NCIMKDED_00929 4.4e-247 G Major Facilitator
NCIMKDED_00930 8.8e-81 E Zn peptidase
NCIMKDED_00931 1e-41 ps115 K Helix-turn-helix XRE-family like proteins
NCIMKDED_00932 6.8e-43
NCIMKDED_00933 2e-52 S Bacteriocin helveticin-J
NCIMKDED_00934 1.3e-37
NCIMKDED_00935 4.4e-45
NCIMKDED_00936 8.1e-137 XK27_08845 S ABC transporter, ATP-binding protein
NCIMKDED_00937 1.1e-119 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
NCIMKDED_00938 4.4e-175 ABC-SBP S ABC transporter
NCIMKDED_00939 1.3e-288 V ABC-type multidrug transport system, ATPase and permease components
NCIMKDED_00940 1.7e-148 ropB K Helix-turn-helix domain
NCIMKDED_00941 3.5e-134 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NCIMKDED_00942 5.1e-151 P CorA-like Mg2+ transporter protein
NCIMKDED_00943 2.3e-156 yvgN C Aldo keto reductase
NCIMKDED_00944 0.0 tetP J elongation factor G
NCIMKDED_00945 2.4e-150 3.1.3.102, 3.1.3.104 S haloacid dehalogenase-like hydrolase
NCIMKDED_00946 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NCIMKDED_00947 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NCIMKDED_00948 1.7e-29 secG U Preprotein translocase
NCIMKDED_00949 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NCIMKDED_00950 1.5e-178 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NCIMKDED_00951 2.6e-202 cpoA GT4 M Glycosyltransferase, group 1 family protein
NCIMKDED_00952 7.9e-224 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
NCIMKDED_00974 2.2e-159 xth 3.1.11.2 L exodeoxyribonuclease III
NCIMKDED_00975 1.3e-273 E amino acid
NCIMKDED_00976 0.0 L Helicase C-terminal domain protein
NCIMKDED_00977 6.2e-205 pbpX1 V Beta-lactamase
NCIMKDED_00978 1.7e-224 N Uncharacterized conserved protein (DUF2075)
NCIMKDED_00979 1.2e-70 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NCIMKDED_00981 1.7e-145 S Putative ABC-transporter type IV
NCIMKDED_00982 4.8e-10 S LPXTG cell wall anchor motif
NCIMKDED_00983 7.8e-29
NCIMKDED_00984 4.2e-127
NCIMKDED_00986 8.7e-10 M Host cell surface-exposed lipoprotein
NCIMKDED_00987 2.9e-31
NCIMKDED_00988 6.2e-42
NCIMKDED_00989 1.2e-23 6.3.4.4 S Zeta toxin
NCIMKDED_00990 4.6e-20 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NCIMKDED_00991 7e-31 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NCIMKDED_00992 5.3e-78 prtS 3.4.21.110, 3.4.21.96 O Belongs to the peptidase S8 family
NCIMKDED_00994 6.9e-94 S Cell surface protein
NCIMKDED_00996 2e-39 S Transglycosylase associated protein
NCIMKDED_00997 1.5e-211 M Glycosyl hydrolases family 25
NCIMKDED_00998 8e-111 XK27_00160 S Domain of unknown function (DUF5052)
NCIMKDED_00999 4.1e-67
NCIMKDED_01000 1.8e-203 xerS L Belongs to the 'phage' integrase family
NCIMKDED_01001 5e-305 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NCIMKDED_01002 3.5e-160 degV S EDD domain protein, DegV family
NCIMKDED_01003 1.1e-66
NCIMKDED_01004 0.0 FbpA K Fibronectin-binding protein
NCIMKDED_01005 2.7e-123 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
NCIMKDED_01006 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
NCIMKDED_01007 4.6e-199 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NCIMKDED_01008 4.3e-169 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NCIMKDED_01009 2.8e-79 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NCIMKDED_01010 8.2e-283 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NCIMKDED_01011 5.5e-53
NCIMKDED_01012 4.4e-158 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
NCIMKDED_01013 7.7e-132 L Domain of unknown function (DUF4368)
NCIMKDED_01014 0.0 tetP J Elongation factor G, domain IV
NCIMKDED_01015 1e-61 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
NCIMKDED_01016 9.7e-74 S Sel1-like repeats.
NCIMKDED_01017 1.4e-104 3.1.4.37 S AAA domain
NCIMKDED_01018 1e-179
NCIMKDED_01019 4.7e-31
NCIMKDED_01020 1.6e-79 S HIRAN
NCIMKDED_01021 6.3e-41 S Sel1-like repeats.
NCIMKDED_01022 2.9e-24 S Sel1-like repeats.
NCIMKDED_01023 6.6e-85
NCIMKDED_01025 2.2e-10 S Domain of unknown function (DUF3841)
NCIMKDED_01028 6.5e-96 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain protein
NCIMKDED_01029 6.3e-264 hsdM 2.1.1.72 V type I restriction-modification system
NCIMKDED_01030 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
NCIMKDED_01031 1.5e-29 S CAAX amino terminal protease
NCIMKDED_01034 2.5e-236 XK27_01810 S Calcineurin-like phosphoesterase
NCIMKDED_01035 1e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
NCIMKDED_01036 1.5e-239 G Bacterial extracellular solute-binding protein
NCIMKDED_01037 1.3e-17
NCIMKDED_01038 3.2e-267 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
NCIMKDED_01039 1.8e-65 treB G phosphotransferase system
NCIMKDED_01040 1.1e-63 spxA_2 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NCIMKDED_01041 1.9e-191 yrvN L AAA C-terminal domain
NCIMKDED_01042 1.7e-251 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NCIMKDED_01043 1.5e-82 K Acetyltransferase (GNAT) domain
NCIMKDED_01044 2e-230 S Putative peptidoglycan binding domain
NCIMKDED_01045 9.8e-95 S ECF-type riboflavin transporter, S component
NCIMKDED_01046 1.9e-99 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
NCIMKDED_01047 7.9e-203 pbpX1 V Beta-lactamase
NCIMKDED_01048 2.2e-116 lacA 2.3.1.79 S Transferase hexapeptide repeat
NCIMKDED_01049 1.9e-80 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NCIMKDED_01050 1.8e-113 3.6.1.27 I Acid phosphatase homologues
NCIMKDED_01051 1.6e-188 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
NCIMKDED_01052 0.0 uvrA3 L excinuclease ABC, A subunit
NCIMKDED_01053 3.4e-82 C Flavodoxin
NCIMKDED_01054 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
NCIMKDED_01055 6.7e-245 ynbB 4.4.1.1 P aluminum resistance
NCIMKDED_01056 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
NCIMKDED_01057 1.7e-284 E Amino acid permease
NCIMKDED_01058 1.6e-93 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
NCIMKDED_01059 4.5e-274 pepV 3.5.1.18 E dipeptidase PepV
NCIMKDED_01060 1.1e-115 mmuP E amino acid
NCIMKDED_01061 1.1e-12 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
NCIMKDED_01062 9.2e-65 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NCIMKDED_01063 7.9e-67 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NCIMKDED_01064 1.1e-152 xerD L Phage integrase, N-terminal SAM-like domain
NCIMKDED_01065 4.9e-64 M LysM domain protein
NCIMKDED_01066 3.7e-44 S aldo-keto reductase (NADP) activity
NCIMKDED_01067 1.4e-74 C Aldo keto reductase
NCIMKDED_01068 4.8e-181 lacX 5.1.3.3 G Aldose 1-epimerase
NCIMKDED_01069 1.6e-227 L COG3547 Transposase and inactivated derivatives
NCIMKDED_01070 3.1e-235 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NCIMKDED_01071 1.9e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NCIMKDED_01072 2.2e-141 xerC D Phage integrase, N-terminal SAM-like domain
NCIMKDED_01073 1.4e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NCIMKDED_01074 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NCIMKDED_01075 1.3e-151 dprA LU DNA protecting protein DprA
NCIMKDED_01076 1.3e-131 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NCIMKDED_01077 7.3e-155 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NCIMKDED_01078 9.1e-182 yjcE P Sodium proton antiporter
NCIMKDED_01079 1e-67 yjcE P NhaP-type Na H and K H
NCIMKDED_01080 7.1e-36 yozE S Belongs to the UPF0346 family
NCIMKDED_01081 9.8e-144 DegV S Uncharacterised protein, DegV family COG1307
NCIMKDED_01082 1.2e-107 hlyIII S protein, hemolysin III
NCIMKDED_01083 7.3e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NCIMKDED_01084 3.3e-158 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NCIMKDED_01085 7.3e-86 3.4.21.96 S SLAP domain
NCIMKDED_01086 2.3e-192 yagE E Amino acid permease
NCIMKDED_01087 1.1e-150 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
NCIMKDED_01088 2.4e-144 2.4.2.3 F Phosphorylase superfamily
NCIMKDED_01089 6.9e-144 2.4.2.3 F Phosphorylase superfamily
NCIMKDED_01090 9.3e-81 S AAA domain
NCIMKDED_01091 2.7e-126 fbiB 6.3.2.12, 6.3.2.17, 6.3.2.31, 6.3.2.34 S F420-0:Gamma-glutamyl ligase
NCIMKDED_01092 1.4e-55 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
NCIMKDED_01093 1e-28 yxaM EGP Major facilitator Superfamily
NCIMKDED_01094 2.5e-53 L An automated process has identified a potential problem with this gene model
NCIMKDED_01095 4.4e-68 L An automated process has identified a potential problem with this gene model
NCIMKDED_01096 4.6e-114 XK27_07525 3.6.1.55 F NUDIX domain
NCIMKDED_01097 1.4e-53 2.4.2.3 F Phosphorylase superfamily
NCIMKDED_01098 8.3e-73 yxaM EGP Major facilitator Superfamily
NCIMKDED_01099 2.8e-140 S Alpha/beta hydrolase family
NCIMKDED_01100 4.5e-94 rimL J Acetyltransferase (GNAT) domain
NCIMKDED_01101 1.7e-262
NCIMKDED_01102 1.1e-126 glsA 3.5.1.2 E Belongs to the glutaminase family
NCIMKDED_01103 1.1e-65
NCIMKDED_01104 4.8e-49
NCIMKDED_01105 5e-282 V ABC transporter transmembrane region
NCIMKDED_01106 5.8e-288 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NCIMKDED_01107 1e-229 S Tetratricopeptide repeat protein
NCIMKDED_01108 2.3e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NCIMKDED_01109 1.9e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NCIMKDED_01110 5.5e-212 rpsA 1.17.7.4 J Ribosomal protein S1
NCIMKDED_01111 2.2e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NCIMKDED_01112 2.7e-18 M Lysin motif
NCIMKDED_01113 7.9e-115 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NCIMKDED_01114 3.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NCIMKDED_01115 4.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NCIMKDED_01116 1.7e-131 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NCIMKDED_01117 2.6e-61 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NCIMKDED_01118 7.6e-166 xerD D recombinase XerD
NCIMKDED_01119 6.8e-167 cvfB S S1 domain
NCIMKDED_01120 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NCIMKDED_01121 3.3e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NCIMKDED_01122 0.0 dnaE 2.7.7.7 L DNA polymerase
NCIMKDED_01123 2.3e-23 S Protein of unknown function (DUF2929)
NCIMKDED_01124 3.6e-309 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NCIMKDED_01125 1.3e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NCIMKDED_01126 1.5e-34 yrvD S Lipopolysaccharide assembly protein A domain
NCIMKDED_01127 6.1e-143 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NCIMKDED_01128 8.4e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NCIMKDED_01129 6.9e-294 I Acyltransferase
NCIMKDED_01130 1.1e-242 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NCIMKDED_01131 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NCIMKDED_01132 1.8e-110 dedA 3.1.3.1 S SNARE associated Golgi protein
NCIMKDED_01133 6.9e-243 yfnA E Amino Acid
NCIMKDED_01134 5.2e-181 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NCIMKDED_01135 2e-149 yxeH S hydrolase
NCIMKDED_01136 2.7e-91 S reductase
NCIMKDED_01137 6.1e-45 S reductase
NCIMKDED_01138 5.8e-214 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NCIMKDED_01139 2e-222 patA 2.6.1.1 E Aminotransferase
NCIMKDED_01140 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NCIMKDED_01141 6.8e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
NCIMKDED_01142 6e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NCIMKDED_01143 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NCIMKDED_01144 2.9e-60
NCIMKDED_01145 1.6e-174 prmA J Ribosomal protein L11 methyltransferase
NCIMKDED_01146 8.2e-85 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NCIMKDED_01147 1.9e-250 yjjP S Putative threonine/serine exporter
NCIMKDED_01148 2.6e-177 citR K Putative sugar-binding domain
NCIMKDED_01149 1.3e-51
NCIMKDED_01150 5.5e-09
NCIMKDED_01151 2.9e-66 S Domain of unknown function DUF1828
NCIMKDED_01152 4.8e-94 S UPF0397 protein
NCIMKDED_01153 0.0 ykoD P ABC transporter, ATP-binding protein
NCIMKDED_01154 3.6e-146 cbiQ P cobalt transport
NCIMKDED_01155 1.8e-22
NCIMKDED_01156 9.3e-72 yeaL S Protein of unknown function (DUF441)
NCIMKDED_01157 4.9e-290 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
NCIMKDED_01158 8.2e-168 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
NCIMKDED_01159 1.2e-43 citD C Covalent carrier of the coenzyme of citrate lyase
NCIMKDED_01160 2.2e-196 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
NCIMKDED_01161 3.8e-153 ydjP I Alpha/beta hydrolase family
NCIMKDED_01162 2.1e-274 P Sodium:sulfate symporter transmembrane region
NCIMKDED_01163 1.3e-133 hxlA 6.2.1.3 H Aldolase/RraA
NCIMKDED_01164 2.1e-257 pepC 3.4.22.40 E Peptidase C1-like family
NCIMKDED_01165 3.1e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NCIMKDED_01166 1.9e-261 frdC 1.3.5.4 C FAD binding domain
NCIMKDED_01167 9e-267 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NCIMKDED_01168 1e-72 metI P ABC transporter permease
NCIMKDED_01169 1e-190 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NCIMKDED_01170 8.5e-159 metQ2 P Belongs to the nlpA lipoprotein family
NCIMKDED_01171 3.7e-24 F DNA/RNA non-specific endonuclease
NCIMKDED_01172 6.4e-62 F DNA/RNA non-specific endonuclease
NCIMKDED_01173 4.7e-134 S SLAP domain
NCIMKDED_01174 1.2e-17 3.6.4.12 K transcriptional regulator containing an HTH domain and an
NCIMKDED_01175 6.4e-251 L Putative transposase DNA-binding domain
NCIMKDED_01176 4.9e-116 L Resolvase, N-terminal
NCIMKDED_01177 2e-140 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NCIMKDED_01180 1.4e-164 psaA P Belongs to the bacterial solute-binding protein 9 family
NCIMKDED_01182 9.1e-139 L COG2826 Transposase and inactivated derivatives, IS30 family
NCIMKDED_01183 8.4e-162 L Transposase
NCIMKDED_01184 6.6e-187 L Transposase
NCIMKDED_01185 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NCIMKDED_01186 4e-57 asp S Asp23 family, cell envelope-related function
NCIMKDED_01187 2e-305 yloV S DAK2 domain fusion protein YloV
NCIMKDED_01188 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NCIMKDED_01189 2.9e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NCIMKDED_01190 1.8e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NCIMKDED_01191 1.1e-192 oppD P Belongs to the ABC transporter superfamily
NCIMKDED_01192 1.5e-170 oppF P Belongs to the ABC transporter superfamily
NCIMKDED_01193 5.7e-172 oppB P ABC transporter permease
NCIMKDED_01194 1.8e-130 oppC P Binding-protein-dependent transport system inner membrane component
NCIMKDED_01196 2.6e-55 oppA E ABC transporter substrate-binding protein
NCIMKDED_01197 3.6e-174 oppA E ABC transporter substrate-binding protein
NCIMKDED_01198 2.5e-311 oppA E ABC transporter substrate-binding protein
NCIMKDED_01199 2.5e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NCIMKDED_01200 0.0 smc D Required for chromosome condensation and partitioning
NCIMKDED_01201 2.5e-162 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NCIMKDED_01202 3.8e-289 pipD E Dipeptidase
NCIMKDED_01203 4.2e-08
NCIMKDED_01204 2.4e-133 cysA V ABC transporter, ATP-binding protein
NCIMKDED_01205 0.0 V FtsX-like permease family
NCIMKDED_01206 1.7e-260 yfnA E amino acid
NCIMKDED_01207 4.6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NCIMKDED_01208 5.8e-229 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NCIMKDED_01209 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NCIMKDED_01210 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NCIMKDED_01211 5e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NCIMKDED_01212 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NCIMKDED_01213 6.4e-215 S SLAP domain
NCIMKDED_01214 4.9e-122 ung2 3.2.2.27 L Uracil-DNA glycosylase
NCIMKDED_01215 2e-146 E GDSL-like Lipase/Acylhydrolase family
NCIMKDED_01216 2e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NCIMKDED_01217 3e-38 ynzC S UPF0291 protein
NCIMKDED_01218 4.2e-30 yneF S Uncharacterised protein family (UPF0154)
NCIMKDED_01219 0.0 mdlA V ABC transporter
NCIMKDED_01220 0.0 mdlB V ABC transporter
NCIMKDED_01221 0.0 pepO 3.4.24.71 O Peptidase family M13
NCIMKDED_01222 3.6e-31 npr 1.11.1.1 C NADH oxidase
NCIMKDED_01223 4.4e-85 dps P Belongs to the Dps family
NCIMKDED_01224 4.5e-311 oppA E ABC transporter substrate-binding protein
NCIMKDED_01225 1.3e-132 S SLAP domain
NCIMKDED_01226 1.2e-98 L An automated process has identified a potential problem with this gene model
NCIMKDED_01228 4.4e-21 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
NCIMKDED_01229 2.6e-22
NCIMKDED_01230 1.1e-61 L PFAM IS66 Orf2 family protein
NCIMKDED_01231 8.7e-34 S Transposase C of IS166 homeodomain
NCIMKDED_01232 7.5e-247 L Transposase IS66 family
NCIMKDED_01233 1.2e-286 atl 3.2.1.96, 3.5.1.28 GH73 UW LPXTG-motif cell wall anchor domain protein
NCIMKDED_01234 2e-227 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
NCIMKDED_01235 1.9e-112 plsC 2.3.1.51 I Acyltransferase
NCIMKDED_01236 1.2e-191 yabB 2.1.1.223 L Methyltransferase small domain
NCIMKDED_01237 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
NCIMKDED_01238 8.3e-185 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NCIMKDED_01239 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NCIMKDED_01240 5.3e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NCIMKDED_01241 1.6e-137 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NCIMKDED_01242 9.6e-136 cdsA 2.7.7.41 I Belongs to the CDS family
NCIMKDED_01243 7.5e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NCIMKDED_01244 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NCIMKDED_01245 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NCIMKDED_01246 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
NCIMKDED_01247 1.3e-197 nusA K Participates in both transcription termination and antitermination
NCIMKDED_01248 8.8e-47 ylxR K Protein of unknown function (DUF448)
NCIMKDED_01249 3.2e-47 rplGA J ribosomal protein
NCIMKDED_01250 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NCIMKDED_01251 3e-60 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NCIMKDED_01252 3.4e-158 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NCIMKDED_01253 7.1e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NCIMKDED_01254 4.5e-194 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NCIMKDED_01255 8e-68 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NCIMKDED_01256 0.0 dnaK O Heat shock 70 kDa protein
NCIMKDED_01257 1.9e-201 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NCIMKDED_01258 9.3e-80 apfA 2.7.7.72, 3.6.1.61 F NUDIX domain
NCIMKDED_01259 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NCIMKDED_01260 8.1e-112 srtA 3.4.22.70 M sortase family
NCIMKDED_01261 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NCIMKDED_01262 9.7e-97 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NCIMKDED_01263 1.5e-202 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
NCIMKDED_01264 1.2e-210 S Bacterial protein of unknown function (DUF871)
NCIMKDED_01266 5.6e-40 ybhL S Belongs to the BI1 family
NCIMKDED_01267 1.4e-50 S Metal binding domain of Ada
NCIMKDED_01268 0.0 mgtA 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
NCIMKDED_01269 6.9e-137 lysR5 K LysR substrate binding domain
NCIMKDED_01270 5e-226 arcA 3.5.3.6 E Arginine
NCIMKDED_01271 3.9e-108 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NCIMKDED_01272 2.2e-108 argF 2.1.3.3, 2.7.2.2 E Belongs to the carbamate kinase family
NCIMKDED_01273 2e-97 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
NCIMKDED_01274 5.6e-222 S Sterol carrier protein domain
NCIMKDED_01275 1e-20
NCIMKDED_01276 4.4e-109 K LysR substrate binding domain
NCIMKDED_01277 9e-98
NCIMKDED_01278 4.3e-118 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
NCIMKDED_01279 2.1e-95
NCIMKDED_01280 5.2e-287 V ABC-type multidrug transport system, ATPase and permease components
NCIMKDED_01281 2.4e-284 V ABC-type multidrug transport system, ATPase and permease components
NCIMKDED_01282 7.1e-74
NCIMKDED_01283 1.7e-50 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
NCIMKDED_01284 2.1e-74 hipB K sequence-specific DNA binding
NCIMKDED_01285 0.0 L PLD-like domain
NCIMKDED_01286 7.4e-103 pgm3 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
NCIMKDED_01287 2.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
NCIMKDED_01288 2.4e-281 thrC 4.2.3.1 E Threonine synthase
NCIMKDED_01289 5e-221 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
NCIMKDED_01290 1.9e-158 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NCIMKDED_01291 7.2e-118
NCIMKDED_01292 9.3e-161 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NCIMKDED_01294 1.9e-106 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NCIMKDED_01295 5.9e-117 S Peptidase family M23
NCIMKDED_01296 8.7e-104
NCIMKDED_01297 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
NCIMKDED_01298 3.9e-34 copZ C Heavy-metal-associated domain
NCIMKDED_01299 1.2e-94 dps P Belongs to the Dps family
NCIMKDED_01300 1.8e-113 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
NCIMKDED_01302 0.0 UW LPXTG-motif cell wall anchor domain protein
NCIMKDED_01303 3.2e-107 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NCIMKDED_01304 6.1e-154 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NCIMKDED_01305 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NCIMKDED_01306 1.6e-71 yqeY S YqeY-like protein
NCIMKDED_01307 1.1e-175 phoH T phosphate starvation-inducible protein PhoH
NCIMKDED_01308 2.2e-93 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NCIMKDED_01309 2.3e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NCIMKDED_01310 6.1e-227 L COG3547 Transposase and inactivated derivatives
NCIMKDED_01311 3.9e-72 L IS1381, transposase OrfA
NCIMKDED_01312 5.3e-22 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NCIMKDED_01313 2.3e-184 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
NCIMKDED_01314 2.3e-116 dedA S SNARE-like domain protein
NCIMKDED_01315 6.3e-100 S Protein of unknown function (DUF1461)
NCIMKDED_01316 4.1e-144 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NCIMKDED_01317 6.4e-105 yutD S Protein of unknown function (DUF1027)
NCIMKDED_01318 1.2e-274 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NCIMKDED_01319 4.3e-55
NCIMKDED_01320 2.3e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NCIMKDED_01321 4.9e-182 ccpA K catabolite control protein A
NCIMKDED_01322 9.1e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NCIMKDED_01323 1.3e-36
NCIMKDED_01324 9.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NCIMKDED_01325 2.5e-147 ykuT M mechanosensitive ion channel
NCIMKDED_01326 5.7e-17
NCIMKDED_01327 1.7e-171 K sequence-specific DNA binding
NCIMKDED_01328 6.5e-108 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NCIMKDED_01329 1e-129 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NCIMKDED_01330 1.1e-71 yslB S Protein of unknown function (DUF2507)
NCIMKDED_01331 9.7e-59 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NCIMKDED_01332 3.5e-54 trxA O Belongs to the thioredoxin family
NCIMKDED_01333 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NCIMKDED_01334 1.1e-50 yrzB S Belongs to the UPF0473 family
NCIMKDED_01335 6.1e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NCIMKDED_01336 2e-42 yrzL S Belongs to the UPF0297 family
NCIMKDED_01337 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NCIMKDED_01338 4.7e-228 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NCIMKDED_01339 4.7e-182 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
NCIMKDED_01340 5.9e-216 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NCIMKDED_01341 1.8e-286 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NCIMKDED_01342 9.6e-41 yajC U Preprotein translocase
NCIMKDED_01343 6.7e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NCIMKDED_01344 4.5e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NCIMKDED_01345 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NCIMKDED_01346 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NCIMKDED_01347 2.6e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NCIMKDED_01348 1.4e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NCIMKDED_01349 1.7e-74
NCIMKDED_01350 2.3e-181 M CHAP domain
NCIMKDED_01351 0.0 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
NCIMKDED_01352 2.4e-294 scrB 3.2.1.26 GH32 G invertase
NCIMKDED_01353 3.3e-183 scrR K helix_turn _helix lactose operon repressor
NCIMKDED_01354 5.8e-112 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NCIMKDED_01355 0.0 uup S ABC transporter, ATP-binding protein
NCIMKDED_01356 7.7e-61 L COG2963 Transposase and inactivated derivatives
NCIMKDED_01357 1.6e-219 L COG3547 Transposase and inactivated derivatives
NCIMKDED_01358 7.4e-197 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NCIMKDED_01359 7.4e-97 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
NCIMKDED_01360 6.9e-133 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
NCIMKDED_01361 2.4e-87 S ECF transporter, substrate-specific component
NCIMKDED_01362 1.7e-136 fat 3.1.2.21 I Acyl-ACP thioesterase
NCIMKDED_01363 3e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NCIMKDED_01364 1.8e-59 yabA L Involved in initiation control of chromosome replication
NCIMKDED_01365 3e-156 holB 2.7.7.7 L DNA polymerase III
NCIMKDED_01366 8.9e-53 yaaQ S Cyclic-di-AMP receptor
NCIMKDED_01367 1.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NCIMKDED_01368 2.4e-34 S Protein of unknown function (DUF2508)
NCIMKDED_01369 1.6e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NCIMKDED_01370 2.8e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NCIMKDED_01371 1.2e-35 M lipopolysaccharide 3-alpha-galactosyltransferase activity
NCIMKDED_01372 9.4e-43 2.4.1.58 GT8 M family 8
NCIMKDED_01373 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NCIMKDED_01374 2.2e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NCIMKDED_01375 9e-26
NCIMKDED_01376 3.8e-116 rsmC 2.1.1.172 J Methyltransferase
NCIMKDED_01377 6e-141 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
NCIMKDED_01378 1.8e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NCIMKDED_01379 4.5e-83 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NCIMKDED_01380 7.8e-13 GT2,GT4 M family 8
NCIMKDED_01381 1.7e-37 L An automated process has identified a potential problem with this gene model
NCIMKDED_01382 7.5e-118 phoU P Plays a role in the regulation of phosphate uptake
NCIMKDED_01383 7.8e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NCIMKDED_01384 6.5e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NCIMKDED_01385 1.2e-155 pstA P Phosphate transport system permease protein PstA
NCIMKDED_01386 1.2e-161 pstC P probably responsible for the translocation of the substrate across the membrane
NCIMKDED_01387 2.8e-157 pstS P Phosphate
NCIMKDED_01388 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NCIMKDED_01389 1.2e-68 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NCIMKDED_01390 3.1e-101 nusG K Participates in transcription elongation, termination and antitermination
NCIMKDED_01391 3.6e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NCIMKDED_01392 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NCIMKDED_01393 4.5e-288 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
NCIMKDED_01394 1.7e-34
NCIMKDED_01395 5.5e-95 sigH K Belongs to the sigma-70 factor family
NCIMKDED_01396 1.7e-139 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NCIMKDED_01397 2.3e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NCIMKDED_01398 2e-277 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NCIMKDED_01399 1.9e-291 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NCIMKDED_01400 2.7e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NCIMKDED_01401 1.8e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
NCIMKDED_01402 3.2e-52
NCIMKDED_01403 3e-267 pepC 3.4.22.40 E Peptidase C1-like family
NCIMKDED_01404 1.1e-183 S AAA domain
NCIMKDED_01405 1.2e-126 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NCIMKDED_01406 1.4e-23
NCIMKDED_01407 5.1e-162 czcD P cation diffusion facilitator family transporter
NCIMKDED_01408 5.8e-126 gpmB G Belongs to the phosphoglycerate mutase family
NCIMKDED_01409 3.8e-134 S membrane transporter protein
NCIMKDED_01410 7.3e-118 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NCIMKDED_01411 2.6e-106 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
NCIMKDED_01412 3.5e-79 K Acetyltransferase (GNAT) domain
NCIMKDED_01413 1.1e-145 M Belongs to the glycosyl hydrolase 28 family
NCIMKDED_01414 2.2e-08 2.3.1.183 M FR47-like protein
NCIMKDED_01416 5.8e-69 5.4.2.11 G Phosphoglycerate mutase family
NCIMKDED_01417 1.1e-21
NCIMKDED_01418 3.6e-54
NCIMKDED_01419 7.9e-67 rpsI J Belongs to the universal ribosomal protein uS9 family
NCIMKDED_01420 5.9e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NCIMKDED_01421 3e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NCIMKDED_01422 2.6e-138 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NCIMKDED_01423 4.6e-157 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NCIMKDED_01424 1.1e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NCIMKDED_01425 1.4e-60 rplQ J Ribosomal protein L17
NCIMKDED_01426 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NCIMKDED_01427 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NCIMKDED_01428 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NCIMKDED_01429 7.8e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NCIMKDED_01430 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NCIMKDED_01431 3.5e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NCIMKDED_01432 1.1e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NCIMKDED_01433 2.6e-71 rplO J Binds to the 23S rRNA
NCIMKDED_01434 2.3e-24 rpmD J Ribosomal protein L30
NCIMKDED_01435 4.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NCIMKDED_01436 3.6e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NCIMKDED_01437 3.3e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NCIMKDED_01438 3.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NCIMKDED_01439 6.8e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NCIMKDED_01440 5.5e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NCIMKDED_01441 3.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NCIMKDED_01442 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NCIMKDED_01443 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NCIMKDED_01444 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
NCIMKDED_01445 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NCIMKDED_01446 2.7e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NCIMKDED_01447 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NCIMKDED_01448 1.1e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NCIMKDED_01449 7.3e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NCIMKDED_01450 3.1e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NCIMKDED_01451 2.1e-106 rplD J Forms part of the polypeptide exit tunnel
NCIMKDED_01452 9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NCIMKDED_01453 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NCIMKDED_01454 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NCIMKDED_01455 2.7e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NCIMKDED_01456 7.8e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NCIMKDED_01457 3.6e-120 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
NCIMKDED_01458 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NCIMKDED_01459 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NCIMKDED_01460 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NCIMKDED_01461 1.1e-80 yebR 1.8.4.14 T GAF domain-containing protein
NCIMKDED_01465 2.3e-60
NCIMKDED_01466 2.2e-259 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
NCIMKDED_01467 0.0 O Belongs to the peptidase S8 family
NCIMKDED_01468 7.5e-175 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
NCIMKDED_01469 1.9e-93 dhaL 2.7.1.121 S Dak2
NCIMKDED_01470 2.9e-55 dhaM 2.7.1.121 S PTS system fructose IIA component
NCIMKDED_01471 6.9e-122 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NCIMKDED_01472 5.9e-188 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NCIMKDED_01473 2.3e-144 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
NCIMKDED_01474 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
NCIMKDED_01475 1.2e-164 lacR K Transcriptional regulator
NCIMKDED_01476 0.0 lacS G Transporter
NCIMKDED_01477 0.0 lacZ 3.2.1.23 G -beta-galactosidase
NCIMKDED_01478 2.1e-221 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NCIMKDED_01479 1.4e-286 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NCIMKDED_01480 1.7e-195 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NCIMKDED_01481 5.5e-36
NCIMKDED_01482 1.2e-164 scrR K Periplasmic binding protein domain
NCIMKDED_01483 1.2e-238 msmE G Bacterial extracellular solute-binding protein
NCIMKDED_01484 6.2e-157 msmF P Binding-protein-dependent transport system inner membrane component
NCIMKDED_01485 5.2e-153 msmG P Binding-protein-dependent transport system inner membrane component
NCIMKDED_01486 2.8e-210 msmX P Belongs to the ABC transporter superfamily
NCIMKDED_01487 0.0 rafA 3.2.1.22 G alpha-galactosidase
NCIMKDED_01488 1.3e-281 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
NCIMKDED_01489 1.9e-112 2.7.6.5 T Region found in RelA / SpoT proteins
NCIMKDED_01490 1.4e-103 K response regulator
NCIMKDED_01491 4.7e-222 sptS 2.7.13.3 T Histidine kinase
NCIMKDED_01492 4.7e-208 EGP Major facilitator Superfamily
NCIMKDED_01493 1.6e-67 O OsmC-like protein
NCIMKDED_01494 2.6e-94 S Protein of unknown function (DUF805)
NCIMKDED_01495 2.5e-77
NCIMKDED_01496 6.1e-282
NCIMKDED_01497 1.7e-82 S Fic/DOC family
NCIMKDED_01498 1.7e-279 yjeM E Amino Acid
NCIMKDED_01499 4.4e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NCIMKDED_01500 1.5e-244 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
NCIMKDED_01501 3.4e-48 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NCIMKDED_01502 1.1e-116 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NCIMKDED_01503 1.3e-51 S Iron-sulfur cluster assembly protein
NCIMKDED_01504 1.1e-153 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NCIMKDED_01505 9e-124 sdaAB 4.3.1.17 E Serine dehydratase beta chain
NCIMKDED_01506 6.9e-44
NCIMKDED_01507 1.6e-285 lsa S ABC transporter
NCIMKDED_01508 1.9e-37 clcA P chloride
NCIMKDED_01509 6.9e-20 clcA P chloride
NCIMKDED_01510 1.1e-118 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NCIMKDED_01511 1.6e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NCIMKDED_01512 3.7e-168 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NCIMKDED_01513 4.6e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NCIMKDED_01514 5.5e-183 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NCIMKDED_01515 2e-244 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NCIMKDED_01516 2.4e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NCIMKDED_01517 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NCIMKDED_01518 1.5e-251 lctP C L-lactate permease
NCIMKDED_01519 6.1e-149 glcU U sugar transport
NCIMKDED_01520 7.1e-46
NCIMKDED_01521 5.2e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NCIMKDED_01522 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NCIMKDED_01523 2.6e-42 S Alpha beta hydrolase
NCIMKDED_01524 1.9e-37
NCIMKDED_01525 2.6e-52
NCIMKDED_01526 2.5e-152 S haloacid dehalogenase-like hydrolase
NCIMKDED_01527 1.2e-291 V ABC-type multidrug transport system, ATPase and permease components
NCIMKDED_01528 5.2e-279 V ABC-type multidrug transport system, ATPase and permease components
NCIMKDED_01529 1.5e-64 arsC 1.20.4.1 P Belongs to the ArsC family
NCIMKDED_01530 2.9e-178 I Carboxylesterase family
NCIMKDED_01532 1.9e-207 M Glycosyl hydrolases family 25
NCIMKDED_01533 2.3e-159 cinI S Serine hydrolase (FSH1)
NCIMKDED_01534 3.8e-302 S Predicted membrane protein (DUF2207)
NCIMKDED_01535 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NCIMKDED_01537 1.6e-255 S Uncharacterized protein conserved in bacteria (DUF2325)
NCIMKDED_01538 3.7e-151 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NCIMKDED_01539 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
NCIMKDED_01540 7.8e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NCIMKDED_01541 1e-196 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NCIMKDED_01542 6.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NCIMKDED_01543 3.4e-71 yqhY S Asp23 family, cell envelope-related function
NCIMKDED_01544 2.1e-64 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NCIMKDED_01545 3.4e-144 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NCIMKDED_01546 3.8e-185 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NCIMKDED_01547 1.1e-34 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NCIMKDED_01548 5.4e-153 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NCIMKDED_01549 2.2e-148 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NCIMKDED_01550 2.6e-300 recN L May be involved in recombinational repair of damaged DNA
NCIMKDED_01551 1.1e-77 6.3.3.2 S ASCH
NCIMKDED_01552 2.1e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
NCIMKDED_01553 1.1e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NCIMKDED_01554 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NCIMKDED_01555 2.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NCIMKDED_01556 1.6e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NCIMKDED_01557 1.3e-139 stp 3.1.3.16 T phosphatase
NCIMKDED_01558 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
NCIMKDED_01559 3.3e-166 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NCIMKDED_01560 1.7e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NCIMKDED_01561 1.4e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
NCIMKDED_01562 1.1e-30
NCIMKDED_01563 3.4e-15
NCIMKDED_01564 9.3e-204 S Putative peptidoglycan binding domain
NCIMKDED_01565 8.7e-158 2.7.7.12 C Domain of unknown function (DUF4931)
NCIMKDED_01566 2e-120
NCIMKDED_01567 1.1e-141 S Belongs to the UPF0246 family
NCIMKDED_01568 3.2e-141 aroD S Alpha/beta hydrolase family
NCIMKDED_01569 4.6e-111 G phosphoglycerate mutase
NCIMKDED_01570 1.1e-92 ygfC K Bacterial regulatory proteins, tetR family
NCIMKDED_01571 4.7e-175 hrtB V ABC transporter permease
NCIMKDED_01572 1.5e-102 devA 3.6.3.25 V ABC transporter, ATP-binding protein
NCIMKDED_01573 5.3e-275 pipD E Dipeptidase
NCIMKDED_01574 8e-38
NCIMKDED_01575 3.7e-111 K WHG domain
NCIMKDED_01576 6.4e-96 nqr 1.5.1.36 S NADPH-dependent FMN reductase
NCIMKDED_01577 7e-98 azr 1.5.1.36 S NADPH-dependent FMN reductase
NCIMKDED_01578 1.5e-149 3.1.3.48 T Tyrosine phosphatase family
NCIMKDED_01579 6.6e-181 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NCIMKDED_01580 3e-53 cvpA S Colicin V production protein
NCIMKDED_01581 1.2e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
NCIMKDED_01582 1.3e-148 noc K Belongs to the ParB family
NCIMKDED_01583 3.4e-138 soj D Sporulation initiation inhibitor
NCIMKDED_01584 8.5e-154 spo0J K Belongs to the ParB family
NCIMKDED_01585 9.6e-45 yyzM S Bacterial protein of unknown function (DUF951)
NCIMKDED_01586 3.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NCIMKDED_01587 1.4e-136 XK27_01040 S Protein of unknown function (DUF1129)
NCIMKDED_01588 9.6e-303 V ABC transporter, ATP-binding protein
NCIMKDED_01589 0.0 V ABC transporter
NCIMKDED_01591 4e-202 L Probable transposase
NCIMKDED_01592 3e-39 S HicB family
NCIMKDED_01593 9.6e-121 K response regulator
NCIMKDED_01594 4.6e-208 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
NCIMKDED_01595 5.5e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NCIMKDED_01596 8e-145 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NCIMKDED_01597 9.6e-55 S Enterocin A Immunity
NCIMKDED_01598 2.5e-33
NCIMKDED_01599 1.2e-25
NCIMKDED_01600 3e-24
NCIMKDED_01601 6e-271 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
NCIMKDED_01602 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
NCIMKDED_01603 6.4e-11
NCIMKDED_01604 1.8e-77
NCIMKDED_01605 5.3e-30 yozG K Transcriptional regulator
NCIMKDED_01606 5.3e-24
NCIMKDED_01607 1.4e-53
NCIMKDED_01608 4.9e-29
NCIMKDED_01609 9.2e-164 natA S ABC transporter, ATP-binding protein
NCIMKDED_01610 5.1e-218 natB CP ABC-2 family transporter protein
NCIMKDED_01611 1.8e-136 fruR K DeoR C terminal sensor domain
NCIMKDED_01612 2.2e-168 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NCIMKDED_01613 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
NCIMKDED_01614 5.4e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
NCIMKDED_01615 4.9e-149 psaA P Belongs to the bacterial solute-binding protein 9 family
NCIMKDED_01616 1.6e-117 fhuC P ABC transporter
NCIMKDED_01617 2.5e-128 znuB U ABC 3 transport family
NCIMKDED_01618 9.4e-262 lctP C L-lactate permease
NCIMKDED_01619 5.2e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NCIMKDED_01620 2.7e-213 2.1.1.14 E methionine synthase, vitamin-B12 independent
NCIMKDED_01621 1.3e-69 doc S Prophage maintenance system killer protein
NCIMKDED_01622 2.9e-31
NCIMKDED_01623 0.0 pepF E oligoendopeptidase F
NCIMKDED_01624 1.1e-210 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NCIMKDED_01625 6.5e-125 S Protein of unknown function (DUF554)
NCIMKDED_01626 5.3e-98
NCIMKDED_01627 2.2e-102 rimL J Acetyltransferase (GNAT) domain
NCIMKDED_01628 2.5e-62
NCIMKDED_01629 7.1e-289 S ABC transporter
NCIMKDED_01630 7e-136 thrE S Putative threonine/serine exporter
NCIMKDED_01631 3.6e-82 S Threonine/Serine exporter, ThrE
NCIMKDED_01632 3.5e-111 yvpB S Peptidase_C39 like family
NCIMKDED_01633 8.6e-69
NCIMKDED_01634 2.2e-176 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NCIMKDED_01635 2.2e-78 nrdI F NrdI Flavodoxin like
NCIMKDED_01636 6.6e-223 tnpB L Putative transposase DNA-binding domain
NCIMKDED_01637 2.2e-111
NCIMKDED_01638 4.5e-280 S O-antigen ligase like membrane protein
NCIMKDED_01639 9.3e-44
NCIMKDED_01640 2.7e-94 gmk2 2.7.4.8 F Guanylate kinase homologues.
NCIMKDED_01641 4.7e-86 M NlpC/P60 family
NCIMKDED_01642 3e-136 M NlpC P60 family protein
NCIMKDED_01643 2e-118 M NlpC/P60 family
NCIMKDED_01644 1.5e-12
NCIMKDED_01646 6.8e-179 S Cysteine-rich secretory protein family
NCIMKDED_01647 3.6e-222 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NCIMKDED_01649 1.3e-41 relB L RelB antitoxin
NCIMKDED_01650 3.8e-177 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NCIMKDED_01651 3e-143 epsB M biosynthesis protein
NCIMKDED_01652 5.2e-123 ywqD 2.7.10.1 D Capsular exopolysaccharide family
NCIMKDED_01653 1.1e-146 ywqE 3.1.3.48 GM PHP domain protein
NCIMKDED_01654 7.6e-99 rfbP 2.7.8.6 M Bacterial sugar transferase
NCIMKDED_01655 1.4e-117 cps1D M Domain of unknown function (DUF4422)
NCIMKDED_01656 6.4e-36 GT2 M transferase activity, transferring glycosyl groups
NCIMKDED_01657 1.3e-84 M Glycosyl transferases group 1
NCIMKDED_01658 1.4e-59 S Psort location CytoplasmicMembrane, score 9.99
NCIMKDED_01659 3e-81 M Glycosyltransferase like family 2
NCIMKDED_01660 6e-205 glf 5.4.99.9 M UDP-galactopyranose mutase
NCIMKDED_01661 2.8e-255 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
NCIMKDED_01663 1e-38 L COG2826 Transposase and inactivated derivatives, IS30 family
NCIMKDED_01664 3.4e-126 L COG2826 Transposase and inactivated derivatives, IS30 family
NCIMKDED_01665 3.3e-10
NCIMKDED_01666 1e-36
NCIMKDED_01667 8.8e-34 S Protein of unknown function (DUF3037)
NCIMKDED_01668 6.9e-22 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NCIMKDED_01670 7.5e-32
NCIMKDED_01672 7.1e-94 J Domain of unknown function (DUF4041)
NCIMKDED_01673 5.2e-35 L Transposase
NCIMKDED_01674 4e-122 L Transposase
NCIMKDED_01675 6.2e-57 M Glycosyltransferase sugar-binding region containing DXD motif
NCIMKDED_01676 1.4e-83 ydcK S Belongs to the SprT family
NCIMKDED_01678 2.5e-86 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
NCIMKDED_01679 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NCIMKDED_01680 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NCIMKDED_01681 5.8e-203 camS S sex pheromone
NCIMKDED_01682 3.4e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NCIMKDED_01683 7.6e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NCIMKDED_01684 4.1e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NCIMKDED_01685 7.2e-172 yegS 2.7.1.107 G Lipid kinase
NCIMKDED_01686 4.3e-108 ybhL S Belongs to the BI1 family
NCIMKDED_01687 2.6e-57
NCIMKDED_01688 4.2e-88 I transferase activity, transferring acyl groups other than amino-acyl groups
NCIMKDED_01689 2.8e-244 nhaC C Na H antiporter NhaC
NCIMKDED_01690 6.3e-201 pbpX V Beta-lactamase
NCIMKDED_01691 2.2e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NCIMKDED_01692 1.1e-94 MA20_25245 K Acetyltransferase (GNAT) domain
NCIMKDED_01697 2.3e-260 emrY EGP Major facilitator Superfamily
NCIMKDED_01698 3.3e-33 4.2.1.53 S Myosin-crossreactive antigen
NCIMKDED_01699 8.8e-43 2.3.1.128 K Acetyltransferase (GNAT) domain
NCIMKDED_01700 1e-92 K Helix-turn-helix XRE-family like proteins
NCIMKDED_01701 1.6e-206 V ABC transporter transmembrane region
NCIMKDED_01702 6.3e-46
NCIMKDED_01703 7.8e-157 S reductase
NCIMKDED_01704 9.3e-35
NCIMKDED_01705 1.4e-292 K Putative DNA-binding domain
NCIMKDED_01706 5.8e-239 pyrP F Permease
NCIMKDED_01707 1.1e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NCIMKDED_01708 9.2e-262 emrY EGP Major facilitator Superfamily
NCIMKDED_01709 7.3e-167 mdtG EGP Major facilitator Superfamily
NCIMKDED_01710 1.3e-28 mdtG EGP Major facilitator Superfamily
NCIMKDED_01711 2.4e-136
NCIMKDED_01712 2.6e-103
NCIMKDED_01713 1.3e-209 pepA E M42 glutamyl aminopeptidase
NCIMKDED_01714 2.7e-310 ybiT S ABC transporter, ATP-binding protein
NCIMKDED_01715 5.9e-174 S Aldo keto reductase
NCIMKDED_01716 3e-150
NCIMKDED_01717 4e-240 steT E amino acid
NCIMKDED_01718 1.8e-232 steT E amino acid
NCIMKDED_01719 1.4e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
NCIMKDED_01720 3.8e-148 glnH ET ABC transporter
NCIMKDED_01721 1.4e-80 K Transcriptional regulator, MarR family
NCIMKDED_01722 1.7e-310 XK27_09600 V ABC transporter, ATP-binding protein
NCIMKDED_01723 0.0 V ABC transporter transmembrane region
NCIMKDED_01724 3.8e-102 S ABC-type cobalt transport system, permease component
NCIMKDED_01725 3.3e-253 G MFS/sugar transport protein
NCIMKDED_01726 3.6e-114 udk 2.7.1.48 F Zeta toxin
NCIMKDED_01727 1.9e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NCIMKDED_01728 2.4e-150 glnH ET ABC transporter substrate-binding protein
NCIMKDED_01729 9.7e-91 gluC P ABC transporter permease
NCIMKDED_01730 4.7e-109 glnP P ABC transporter permease
NCIMKDED_01731 6.5e-165 S Protein of unknown function (DUF2974)
NCIMKDED_01732 5.6e-86
NCIMKDED_01733 7.8e-202 S Uncharacterized protein conserved in bacteria (DUF2325)
NCIMKDED_01734 1e-235 G Bacterial extracellular solute-binding protein
NCIMKDED_01735 3.5e-162 2.7.7.12 C Domain of unknown function (DUF4931)
NCIMKDED_01736 5.4e-167 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NCIMKDED_01737 2.6e-126 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NCIMKDED_01738 0.0 kup P Transport of potassium into the cell
NCIMKDED_01739 3.1e-175 rihB 3.2.2.1 F Nucleoside
NCIMKDED_01740 2.8e-134 ydhQ K UbiC transcription regulator-associated domain protein
NCIMKDED_01741 6.1e-154 S hydrolase
NCIMKDED_01742 1.9e-59 S Enterocin A Immunity
NCIMKDED_01743 3.7e-137 glcR K DeoR C terminal sensor domain
NCIMKDED_01744 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
NCIMKDED_01745 1.1e-153 rssA S Phospholipase, patatin family
NCIMKDED_01746 7.5e-149 S hydrolase
NCIMKDED_01747 0.0 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
NCIMKDED_01748 4.1e-147 glvR K Helix-turn-helix domain, rpiR family
NCIMKDED_01749 7e-81
NCIMKDED_01750 2.9e-87 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NCIMKDED_01751 2.1e-39
NCIMKDED_01752 6.6e-119 C nitroreductase
NCIMKDED_01753 7.4e-250 yhdP S Transporter associated domain
NCIMKDED_01754 2.6e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NCIMKDED_01755 0.0 1.3.5.4 C FAD binding domain
NCIMKDED_01756 1.2e-89 L PFAM transposase, IS4 family protein
NCIMKDED_01757 0.0 1.3.5.4 C FAD binding domain
NCIMKDED_01758 9.7e-231 potE E amino acid
NCIMKDED_01759 4.7e-131 M Glycosyl hydrolases family 25
NCIMKDED_01760 4e-210 yfmL 3.6.4.13 L DEAD DEAH box helicase
NCIMKDED_01761 8.9e-248 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NCIMKDED_01763 1.6e-219 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NCIMKDED_01764 1.7e-260 qacA EGP Major facilitator Superfamily
NCIMKDED_01765 0.0 sacX 2.7.1.208, 2.7.1.211 G phosphotransferase system
NCIMKDED_01766 3.9e-154 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NCIMKDED_01767 8.6e-198 S Bacterial protein of unknown function (DUF871)
NCIMKDED_01768 1.3e-148 ybbH_2 K rpiR family
NCIMKDED_01769 2.3e-273 cydA 1.10.3.14 C ubiquinol oxidase
NCIMKDED_01770 3.3e-178 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
NCIMKDED_01771 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NCIMKDED_01772 1.9e-269 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NCIMKDED_01773 4.4e-129 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NCIMKDED_01774 5.5e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NCIMKDED_01775 3e-162 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
NCIMKDED_01776 1.1e-231 ndh 1.6.99.3 C NADH dehydrogenase
NCIMKDED_01777 2.1e-91 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NCIMKDED_01778 2.2e-168 K LysR substrate binding domain
NCIMKDED_01779 3.2e-121 3.6.1.27 I Acid phosphatase homologues
NCIMKDED_01780 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NCIMKDED_01781 1e-298 ytgP S Polysaccharide biosynthesis protein
NCIMKDED_01782 1.5e-44 pspC KT PspC domain
NCIMKDED_01784 5.1e-240 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NCIMKDED_01785 1.6e-154 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NCIMKDED_01786 7.9e-99 M ErfK YbiS YcfS YnhG
NCIMKDED_01787 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NCIMKDED_01788 1.8e-170 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
NCIMKDED_01789 1.2e-94 3.6.1.55 L NUDIX domain
NCIMKDED_01790 2.6e-73 menA 2.5.1.74 H UbiA prenyltransferase family
NCIMKDED_01792 3.6e-45
NCIMKDED_01793 7.8e-126 2.7.13.3 T GHKL domain
NCIMKDED_01794 5.4e-144 K LytTr DNA-binding domain
NCIMKDED_01795 6.3e-111
NCIMKDED_01797 1.4e-94
NCIMKDED_01799 5.5e-49 yniG EGP Major facilitator Superfamily
NCIMKDED_01800 1e-235 L transposase, IS605 OrfB family
NCIMKDED_01801 3.1e-29 S cog cog1373
NCIMKDED_01802 9.6e-179 S PFAM Archaeal ATPase
NCIMKDED_01803 9.6e-195 I transferase activity, transferring acyl groups other than amino-acyl groups
NCIMKDED_01804 7.4e-128 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
NCIMKDED_01806 1.6e-140 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NCIMKDED_01807 3.6e-111 G Phosphoglycerate mutase family
NCIMKDED_01808 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
NCIMKDED_01809 6.5e-151 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NCIMKDED_01810 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NCIMKDED_01811 7.2e-56 yheA S Belongs to the UPF0342 family
NCIMKDED_01812 1.1e-231 yhaO L Ser Thr phosphatase family protein
NCIMKDED_01813 0.0 L AAA domain
NCIMKDED_01814 5.8e-188 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
NCIMKDED_01815 5.9e-24
NCIMKDED_01816 2.4e-51 S Domain of unknown function DUF1829
NCIMKDED_01817 7.3e-267
NCIMKDED_01818 1.5e-72 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
NCIMKDED_01819 1.5e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NCIMKDED_01820 3.9e-25
NCIMKDED_01821 8.3e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
NCIMKDED_01822 2e-135 ecsA V ABC transporter, ATP-binding protein
NCIMKDED_01823 1.6e-219 ecsB U ABC transporter
NCIMKDED_01824 3.3e-126 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NCIMKDED_01825 5.8e-14 S Protein of unknown function (DUF805)
NCIMKDED_01826 2.8e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NCIMKDED_01827 1.7e-122 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NCIMKDED_01828 1.9e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NCIMKDED_01829 8.7e-235 mepA V MATE efflux family protein
NCIMKDED_01830 6.5e-171 S SLAP domain
NCIMKDED_01831 5.2e-220 L Putative transposase DNA-binding domain
NCIMKDED_01832 6.7e-113 L Resolvase, N-terminal
NCIMKDED_01833 7.1e-250 M Peptidase family M1 domain
NCIMKDED_01834 1.4e-86 tlpA2 L Transposase IS200 like
NCIMKDED_01835 7.5e-255 L transposase, IS605 OrfB family
NCIMKDED_01836 2.3e-28
NCIMKDED_01837 6e-193 S Bacteriocin helveticin-J
NCIMKDED_01839 4.3e-52 L RelB antitoxin
NCIMKDED_01840 7e-140 qmcA O prohibitin homologues
NCIMKDED_01841 4.2e-17 darA C Flavodoxin
NCIMKDED_01842 2.6e-95 purD 6.3.4.13 F Belongs to the GARS family
NCIMKDED_01843 2.4e-95 purD 6.3.4.13 F Belongs to the GARS family
NCIMKDED_01844 2.1e-260 L COG3385 FOG Transposase and inactivated derivatives
NCIMKDED_01845 1.7e-39 UW LPXTG-motif cell wall anchor domain protein
NCIMKDED_01846 1.4e-96 S haloacid dehalogenase-like hydrolase
NCIMKDED_01847 2.6e-225 S cog cog1373
NCIMKDED_01848 7.5e-51 K Transcriptional regulator
NCIMKDED_01849 1.4e-49 K Transcriptional regulator
NCIMKDED_01850 5e-35 ymfI 1.1.1.100, 1.3.1.28 S oxidoreductase activity
NCIMKDED_01851 1.8e-48 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
NCIMKDED_01852 8.2e-17 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
NCIMKDED_01853 2.5e-40 relB L Addiction module antitoxin, RelB DinJ family
NCIMKDED_01854 3e-232 pbuG S permease
NCIMKDED_01855 2.5e-127 K helix_turn_helix, mercury resistance
NCIMKDED_01856 9.9e-222 S cog cog1373
NCIMKDED_01857 2.2e-230 pbuG S permease
NCIMKDED_01858 2.4e-139 cof S haloacid dehalogenase-like hydrolase
NCIMKDED_01859 1.4e-72
NCIMKDED_01860 1.1e-124 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NCIMKDED_01861 6.3e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NCIMKDED_01862 4.4e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NCIMKDED_01863 9.7e-160 yeaE S Aldo/keto reductase family
NCIMKDED_01864 4.4e-172 yufQ S Belongs to the binding-protein-dependent transport system permease family
NCIMKDED_01865 1.9e-198 yufP S Belongs to the binding-protein-dependent transport system permease family
NCIMKDED_01866 5.2e-284 xylG 3.6.3.17 S ABC transporter
NCIMKDED_01867 3.3e-200 tcsA S ABC transporter substrate-binding protein PnrA-like
NCIMKDED_01868 1.8e-201 tcsA S ABC transporter substrate-binding protein PnrA-like
NCIMKDED_01869 1.8e-99 S ECF transporter, substrate-specific component
NCIMKDED_01870 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NCIMKDED_01871 0.0 macB_3 V ABC transporter, ATP-binding protein
NCIMKDED_01872 9.5e-195 S DUF218 domain
NCIMKDED_01873 2e-120 S CAAX protease self-immunity
NCIMKDED_01874 1.2e-53
NCIMKDED_01875 2.2e-151 mutR K Helix-turn-helix XRE-family like proteins
NCIMKDED_01876 7.4e-72 S Putative adhesin
NCIMKDED_01877 4.8e-277 V ABC transporter transmembrane region
NCIMKDED_01878 3.2e-43 S YoeB-like toxin of bacterial type II toxin-antitoxin system
NCIMKDED_01879 1.9e-47 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
NCIMKDED_01880 2.8e-205 napA P Sodium/hydrogen exchanger family
NCIMKDED_01881 5.7e-62
NCIMKDED_01882 0.0 cadA P P-type ATPase
NCIMKDED_01883 5.1e-81 ykuL S (CBS) domain
NCIMKDED_01884 1.7e-215 ywhK S Membrane
NCIMKDED_01885 4.7e-48
NCIMKDED_01886 5.2e-19 S D-Ala-teichoic acid biosynthesis protein
NCIMKDED_01887 4.8e-290 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NCIMKDED_01888 8.3e-240 dltB M MBOAT, membrane-bound O-acyltransferase family
NCIMKDED_01889 4.3e-36 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NCIMKDED_01890 5.2e-245 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NCIMKDED_01891 8.4e-176 pbpX2 V Beta-lactamase
NCIMKDED_01892 7.9e-134 S Protein of unknown function (DUF975)
NCIMKDED_01893 2.7e-137 lysA2 M Glycosyl hydrolases family 25
NCIMKDED_01894 3.5e-291 ytgP S Polysaccharide biosynthesis protein
NCIMKDED_01895 1.9e-36
NCIMKDED_01896 0.0 XK27_06780 V ABC transporter permease
NCIMKDED_01897 2.3e-125 XK27_06785 V ABC transporter, ATP-binding protein
NCIMKDED_01898 8.2e-238 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NCIMKDED_01899 1.2e-168 S Alpha/beta hydrolase of unknown function (DUF915)
NCIMKDED_01900 0.0 clpE O AAA domain (Cdc48 subfamily)
NCIMKDED_01901 1.7e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NCIMKDED_01902 2.3e-233 cycA E Amino acid permease
NCIMKDED_01903 1.2e-247 yifK E Amino acid permease
NCIMKDED_01904 1.5e-135 puuD S peptidase C26
NCIMKDED_01905 3e-230 steT_1 E amino acid
NCIMKDED_01906 2.6e-41 L Helix-turn-helix domain
NCIMKDED_01907 3.1e-102 L PFAM Integrase catalytic region
NCIMKDED_01908 1.3e-190 asnA 6.3.1.1 F aspartate--ammonia ligase
NCIMKDED_01909 2e-205 4.2.1.126 S Bacterial protein of unknown function (DUF871)
NCIMKDED_01912 7e-189 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NCIMKDED_01913 6.4e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NCIMKDED_01914 2.5e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NCIMKDED_01915 1.1e-56
NCIMKDED_01916 3.5e-88
NCIMKDED_01917 2.3e-262 yheS_2 S ATPases associated with a variety of cellular activities
NCIMKDED_01918 4e-187 XK27_05540 S DUF218 domain
NCIMKDED_01919 1.6e-109
NCIMKDED_01920 2.5e-107
NCIMKDED_01921 2.5e-118 yicL EG EamA-like transporter family
NCIMKDED_01922 5.3e-167 EG EamA-like transporter family
NCIMKDED_01923 3e-165 EG EamA-like transporter family
NCIMKDED_01924 9.3e-38
NCIMKDED_01926 8.4e-162
NCIMKDED_01928 4.8e-82 M NlpC/P60 family
NCIMKDED_01929 4.8e-128 cobQ S glutamine amidotransferase
NCIMKDED_01931 3.7e-67 L RelB antitoxin
NCIMKDED_01932 6.5e-44 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
NCIMKDED_01933 5.9e-47 yoeB S YoeB-like toxin of bacterial type II toxin-antitoxin system

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)