ORF_ID e_value Gene_name EC_number CAZy COGs Description
CFDIMMCL_00001 2.2e-30 csfB S Inhibitor of sigma-G Gin
CFDIMMCL_00002 1e-105 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
CFDIMMCL_00003 1.1e-193 yaaN P Belongs to the TelA family
CFDIMMCL_00004 3.2e-275 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
CFDIMMCL_00005 1.5e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CFDIMMCL_00006 7.5e-55 yaaQ S protein conserved in bacteria
CFDIMMCL_00007 5.3e-72 yaaR S protein conserved in bacteria
CFDIMMCL_00008 1.3e-182 holB 2.7.7.7 L DNA polymerase III
CFDIMMCL_00009 8.8e-145 yaaT S stage 0 sporulation protein
CFDIMMCL_00010 7.7e-37 yabA L Involved in initiation control of chromosome replication
CFDIMMCL_00011 1.9e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
CFDIMMCL_00012 4.7e-48 yazA L endonuclease containing a URI domain
CFDIMMCL_00013 1.4e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CFDIMMCL_00014 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
CFDIMMCL_00015 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFDIMMCL_00016 1.6e-145 tatD L hydrolase, TatD
CFDIMMCL_00017 1.8e-232 rpfB GH23 T protein conserved in bacteria
CFDIMMCL_00018 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CFDIMMCL_00019 3e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
CFDIMMCL_00020 8.4e-146 yabG S peptidase
CFDIMMCL_00021 7.8e-39 veg S protein conserved in bacteria
CFDIMMCL_00022 2.9e-27 sspF S DNA topological change
CFDIMMCL_00023 2.1e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CFDIMMCL_00024 1.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
CFDIMMCL_00025 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
CFDIMMCL_00026 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
CFDIMMCL_00027 9.2e-248 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CFDIMMCL_00028 7.2e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CFDIMMCL_00029 2e-106 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CFDIMMCL_00030 2.5e-106 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
CFDIMMCL_00031 3.7e-40 yabK S Peptide ABC transporter permease
CFDIMMCL_00032 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CFDIMMCL_00033 6.2e-91 spoVT K stage V sporulation protein
CFDIMMCL_00034 2.6e-286 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CFDIMMCL_00035 8.3e-279 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
CFDIMMCL_00036 5.6e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
CFDIMMCL_00037 1.9e-49 yabP S Sporulation protein YabP
CFDIMMCL_00038 4.4e-104 yabQ S spore cortex biosynthesis protein
CFDIMMCL_00039 4.1e-57 divIC D Septum formation initiator
CFDIMMCL_00040 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
CFDIMMCL_00043 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
CFDIMMCL_00044 1.1e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
CFDIMMCL_00045 7.3e-186 KLT serine threonine protein kinase
CFDIMMCL_00046 2e-274 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CFDIMMCL_00047 5.1e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
CFDIMMCL_00048 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CFDIMMCL_00049 2.2e-145 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CFDIMMCL_00050 1.1e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CFDIMMCL_00051 3e-159 yacD 5.2.1.8 O peptidyl-prolyl isomerase
CFDIMMCL_00052 1.5e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
CFDIMMCL_00053 2.8e-271 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CFDIMMCL_00054 1e-107 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
CFDIMMCL_00055 3.1e-164 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
CFDIMMCL_00056 3.2e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CFDIMMCL_00057 2.4e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CFDIMMCL_00058 9.9e-91 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CFDIMMCL_00059 4.5e-29 yazB K transcriptional
CFDIMMCL_00060 1.9e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CFDIMMCL_00061 6.4e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
CFDIMMCL_00062 3.4e-39 S COG NOG14552 non supervised orthologous group
CFDIMMCL_00063 7.5e-77 ctsR K Belongs to the CtsR family
CFDIMMCL_00064 4.1e-65 mcsA 2.7.14.1 S protein with conserved CXXC pairs
CFDIMMCL_00065 1.9e-203 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
CFDIMMCL_00066 0.0 clpC O Belongs to the ClpA ClpB family
CFDIMMCL_00067 7e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CFDIMMCL_00068 2.9e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CFDIMMCL_00069 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
CFDIMMCL_00070 1e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
CFDIMMCL_00071 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
CFDIMMCL_00072 2.8e-279 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFDIMMCL_00073 1.6e-117 cysE 2.3.1.30 E Serine acetyltransferase
CFDIMMCL_00074 2.8e-268 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
CFDIMMCL_00075 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CFDIMMCL_00076 2e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFDIMMCL_00077 4.2e-89 yacP S RNA-binding protein containing a PIN domain
CFDIMMCL_00078 8.9e-116 sigH K Belongs to the sigma-70 factor family
CFDIMMCL_00079 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
CFDIMMCL_00080 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
CFDIMMCL_00081 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CFDIMMCL_00082 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
CFDIMMCL_00083 3e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CFDIMMCL_00084 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
CFDIMMCL_00085 9.7e-109 rsmC 2.1.1.172 J Methyltransferase
CFDIMMCL_00086 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CFDIMMCL_00087 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CFDIMMCL_00088 5.5e-34 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
CFDIMMCL_00089 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CFDIMMCL_00090 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
CFDIMMCL_00091 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CFDIMMCL_00092 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CFDIMMCL_00093 4.7e-190 ybaC 3.4.11.5 S Alpha/beta hydrolase family
CFDIMMCL_00094 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
CFDIMMCL_00095 9.8e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CFDIMMCL_00096 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
CFDIMMCL_00097 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
CFDIMMCL_00098 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CFDIMMCL_00099 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CFDIMMCL_00100 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CFDIMMCL_00101 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CFDIMMCL_00102 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CFDIMMCL_00103 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
CFDIMMCL_00104 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CFDIMMCL_00105 2.3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CFDIMMCL_00106 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CFDIMMCL_00107 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CFDIMMCL_00108 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CFDIMMCL_00109 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CFDIMMCL_00110 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CFDIMMCL_00111 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CFDIMMCL_00112 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CFDIMMCL_00113 1.9e-23 rpmD J Ribosomal protein L30
CFDIMMCL_00114 1.1e-72 rplO J binds to the 23S rRNA
CFDIMMCL_00115 3.5e-233 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
CFDIMMCL_00116 1.1e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
CFDIMMCL_00117 5.7e-143 map 3.4.11.18 E Methionine aminopeptidase
CFDIMMCL_00118 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CFDIMMCL_00119 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
CFDIMMCL_00120 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CFDIMMCL_00121 1.3e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CFDIMMCL_00122 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CFDIMMCL_00123 4.7e-58 rplQ J Ribosomal protein L17
CFDIMMCL_00124 3.9e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CFDIMMCL_00125 1.3e-151 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CFDIMMCL_00126 5.3e-139 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CFDIMMCL_00127 5.1e-144 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CFDIMMCL_00128 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CFDIMMCL_00129 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
CFDIMMCL_00130 9.6e-146 ybaJ Q Methyltransferase domain
CFDIMMCL_00131 1.8e-86 yizA S Damage-inducible protein DinB
CFDIMMCL_00132 4.5e-79 ybaK S Protein of unknown function (DUF2521)
CFDIMMCL_00133 2.1e-134 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
CFDIMMCL_00134 5.1e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
CFDIMMCL_00135 5.9e-76 gerD
CFDIMMCL_00136 6e-103 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
CFDIMMCL_00137 8.4e-134 pdaB 3.5.1.104 G Polysaccharide deacetylase
CFDIMMCL_00138 3.4e-39 S COG NOG14552 non supervised orthologous group
CFDIMMCL_00139 2.2e-221 glcP G Major Facilitator Superfamily
CFDIMMCL_00140 1.9e-247 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CFDIMMCL_00141 3.9e-181 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
CFDIMMCL_00142 5.3e-203 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
CFDIMMCL_00143 2.5e-227 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
CFDIMMCL_00144 9.7e-175 ybaS 1.1.1.58 S Na -dependent transporter
CFDIMMCL_00145 8.3e-118 ybbA S Putative esterase
CFDIMMCL_00146 1.2e-180 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFDIMMCL_00147 2.8e-177 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFDIMMCL_00148 2e-172 feuA P Iron-uptake system-binding protein
CFDIMMCL_00149 0.0 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
CFDIMMCL_00150 4.9e-240 ybbC 3.2.1.52 S protein conserved in bacteria
CFDIMMCL_00151 1.8e-273 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
CFDIMMCL_00152 7.1e-44 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
CFDIMMCL_00153 3.5e-249 yfeW 3.4.16.4 V Belongs to the UPF0214 family
CFDIMMCL_00154 1.8e-240 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CFDIMMCL_00155 9.5e-164 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CFDIMMCL_00156 3.7e-87 ybbJ J acetyltransferase
CFDIMMCL_00157 2.3e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
CFDIMMCL_00163 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
CFDIMMCL_00164 5.9e-117 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
CFDIMMCL_00165 1e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CFDIMMCL_00166 1.6e-226 ybbR S protein conserved in bacteria
CFDIMMCL_00167 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CFDIMMCL_00168 7.8e-94 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
CFDIMMCL_00169 4.7e-227 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
CFDIMMCL_00170 2.5e-158 V ATPases associated with a variety of cellular activities
CFDIMMCL_00171 2.1e-109 S ABC-2 family transporter protein
CFDIMMCL_00172 3.7e-28 ybdN
CFDIMMCL_00174 2.6e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CFDIMMCL_00175 4.7e-188 T PhoQ Sensor
CFDIMMCL_00176 4.3e-138 V ABC transporter, ATP-binding protein
CFDIMMCL_00177 0.0 V ABC transporter (permease)
CFDIMMCL_00178 3e-12 cusA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFDIMMCL_00179 3.9e-164 dkgB S Aldo/keto reductase family
CFDIMMCL_00180 1e-93 yxaC M effector of murein hydrolase
CFDIMMCL_00181 6.9e-52 S LrgA family
CFDIMMCL_00182 8e-73 yxaD K helix_turn_helix multiple antibiotic resistance protein
CFDIMMCL_00183 3.1e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
CFDIMMCL_00184 2.7e-94 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
CFDIMMCL_00185 5.1e-204 T COG4585 Signal transduction histidine kinase
CFDIMMCL_00186 2.9e-111 KT LuxR family transcriptional regulator
CFDIMMCL_00187 2.8e-171 V COG1131 ABC-type multidrug transport system, ATPase component
CFDIMMCL_00188 2.3e-210 V COG0842 ABC-type multidrug transport system, permease component
CFDIMMCL_00189 3e-204 V ABC-2 family transporter protein
CFDIMMCL_00190 5.8e-25
CFDIMMCL_00191 3.1e-78 S Domain of unknown function (DUF4879)
CFDIMMCL_00192 2e-39 csgA S Sigma-G-dependent sporulation-specific SASP protein
CFDIMMCL_00193 6.4e-112 yqeB
CFDIMMCL_00194 9.2e-40 ybyB
CFDIMMCL_00195 2.5e-292 ybeC E amino acid
CFDIMMCL_00197 1.9e-55
CFDIMMCL_00198 3.4e-15 S Protein of unknown function (DUF2651)
CFDIMMCL_00199 2.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
CFDIMMCL_00200 1.7e-259 glpT G -transporter
CFDIMMCL_00201 1.3e-16 S Protein of unknown function (DUF2651)
CFDIMMCL_00202 5e-212 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
CFDIMMCL_00204 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
CFDIMMCL_00205 1.3e-30
CFDIMMCL_00206 1.2e-82 K Helix-turn-helix XRE-family like proteins
CFDIMMCL_00207 7e-203 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
CFDIMMCL_00208 6.2e-213 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CFDIMMCL_00209 5e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CFDIMMCL_00210 1.9e-86 ybfM S SNARE associated Golgi protein
CFDIMMCL_00211 6.6e-153 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
CFDIMMCL_00212 6.5e-44 ybfN
CFDIMMCL_00213 2.7e-193 yceA S Belongs to the UPF0176 family
CFDIMMCL_00214 1.9e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CFDIMMCL_00215 8.6e-201 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
CFDIMMCL_00216 4.7e-258 mmuP E amino acid
CFDIMMCL_00217 1.1e-183 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
CFDIMMCL_00218 5.4e-259 agcS E Sodium alanine symporter
CFDIMMCL_00219 1.4e-189 glsA 3.5.1.2 E Belongs to the glutaminase family
CFDIMMCL_00220 1.4e-213 phoQ 2.7.13.3 T Histidine kinase
CFDIMMCL_00221 6.7e-173 glnL T Regulator
CFDIMMCL_00222 8.2e-26 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
CFDIMMCL_00223 2.5e-36 L Transposase
CFDIMMCL_00224 1.8e-156 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CFDIMMCL_00225 1.5e-112 ydfN C nitroreductase
CFDIMMCL_00226 6.2e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
CFDIMMCL_00227 1.5e-62 mhqP S DoxX
CFDIMMCL_00228 2.8e-57 traF CO Thioredoxin
CFDIMMCL_00229 5.6e-62 ycbP S Protein of unknown function (DUF2512)
CFDIMMCL_00230 5.1e-80 sleB 3.5.1.28 M Cell wall
CFDIMMCL_00231 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
CFDIMMCL_00232 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
CFDIMMCL_00233 5.6e-127 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CFDIMMCL_00234 3.1e-121 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CFDIMMCL_00235 6.7e-212 ycbU E Selenocysteine lyase
CFDIMMCL_00236 7.1e-243 lmrB EGP the major facilitator superfamily
CFDIMMCL_00237 5.3e-101 yxaF K Transcriptional regulator
CFDIMMCL_00238 4.7e-202 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
CFDIMMCL_00239 8.7e-116 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
CFDIMMCL_00240 1.5e-197 yccF K DNA-templated transcriptional preinitiation complex assembly
CFDIMMCL_00241 4.6e-174 yccK C Aldo keto reductase
CFDIMMCL_00242 5.6e-178 ycdA S Domain of unknown function (DUF5105)
CFDIMMCL_00243 9.3e-38 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
CFDIMMCL_00244 2.2e-226 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
CFDIMMCL_00245 7.9e-268 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
CFDIMMCL_00246 6.2e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
CFDIMMCL_00247 4.2e-190 S response regulator aspartate phosphatase
CFDIMMCL_00248 5e-142 IQ Enoyl-(Acyl carrier protein) reductase
CFDIMMCL_00249 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
CFDIMMCL_00250 1.2e-164 adcA P Belongs to the bacterial solute-binding protein 9 family
CFDIMMCL_00251 1.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
CFDIMMCL_00252 1.5e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
CFDIMMCL_00253 3.3e-186 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFDIMMCL_00254 4.3e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
CFDIMMCL_00255 3.7e-105 yceD T proteins involved in stress response, homologs of TerZ and
CFDIMMCL_00256 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
CFDIMMCL_00257 9.7e-138 terC P Protein of unknown function (DUF475)
CFDIMMCL_00258 0.0 yceG S Putative component of 'biosynthetic module'
CFDIMMCL_00259 2.3e-193 yceH P Belongs to the TelA family
CFDIMMCL_00260 3.3e-217 naiP P Uncharacterised MFS-type transporter YbfB
CFDIMMCL_00261 3.9e-229 proV 3.6.3.32 E glycine betaine
CFDIMMCL_00262 1.6e-138 opuAB P glycine betaine
CFDIMMCL_00263 3.1e-164 opuAC E glycine betaine
CFDIMMCL_00264 2.1e-213 amhX S amidohydrolase
CFDIMMCL_00265 1.1e-230 ycgA S Membrane
CFDIMMCL_00266 2.2e-82 ycgB
CFDIMMCL_00267 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
CFDIMMCL_00268 5.7e-180 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
CFDIMMCL_00269 9.6e-262 mdr EGP Major facilitator Superfamily
CFDIMMCL_00270 3.7e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
CFDIMMCL_00271 4.7e-114 ycgF E Lysine exporter protein LysE YggA
CFDIMMCL_00272 1.6e-153 yqcI S YqcI/YcgG family
CFDIMMCL_00273 6.4e-58 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
CFDIMMCL_00274 2.7e-180 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
CFDIMMCL_00275 7.6e-114 ycgI S Domain of unknown function (DUF1989)
CFDIMMCL_00276 4.8e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
CFDIMMCL_00278 4.3e-109 tmrB S AAA domain
CFDIMMCL_00279 2.7e-151 4.2.1.118 G Xylose isomerase-like TIM barrel
CFDIMMCL_00280 1.2e-233 G COG0477 Permeases of the major facilitator superfamily
CFDIMMCL_00281 8.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CFDIMMCL_00282 4.5e-185 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
CFDIMMCL_00283 3.6e-148 ycgL S Predicted nucleotidyltransferase
CFDIMMCL_00284 2.3e-170 ycgM E Proline dehydrogenase
CFDIMMCL_00285 1.1e-292 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
CFDIMMCL_00286 2.2e-244 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CFDIMMCL_00287 1.2e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
CFDIMMCL_00288 5.3e-192 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
CFDIMMCL_00289 2.7e-282 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
CFDIMMCL_00290 3.5e-57 nirD 1.7.1.15 P Nitrite reductase
CFDIMMCL_00291 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CFDIMMCL_00292 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CFDIMMCL_00293 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
CFDIMMCL_00294 2.1e-224 nasA P COG2223 Nitrate nitrite transporter
CFDIMMCL_00295 1.3e-229 yciC S GTPases (G3E family)
CFDIMMCL_00296 1.4e-222 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
CFDIMMCL_00297 5.6e-74 yckC S membrane
CFDIMMCL_00298 2.2e-51 S Protein of unknown function (DUF2680)
CFDIMMCL_00299 3.8e-297 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CFDIMMCL_00300 2.9e-69 nin S Competence protein J (ComJ)
CFDIMMCL_00301 2.4e-77 nucA M Deoxyribonuclease NucA/NucB
CFDIMMCL_00302 3.3e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
CFDIMMCL_00303 5.1e-108 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
CFDIMMCL_00304 2.8e-63 hxlR K transcriptional
CFDIMMCL_00305 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFDIMMCL_00306 5.8e-241 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFDIMMCL_00307 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFDIMMCL_00308 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
CFDIMMCL_00309 1.5e-140 srfAD Q thioesterase
CFDIMMCL_00310 7.2e-250 bamJ E Aminotransferase class I and II
CFDIMMCL_00311 1.3e-64 S YcxB-like protein
CFDIMMCL_00313 3.2e-170 ycxC EG EamA-like transporter family
CFDIMMCL_00314 4.6e-249 ycxD K GntR family transcriptional regulator
CFDIMMCL_00315 1.6e-131 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
CFDIMMCL_00316 1.3e-111 yczE S membrane
CFDIMMCL_00317 1.1e-133 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
CFDIMMCL_00318 6.4e-120 tcyB P COG0765 ABC-type amino acid transport system, permease component
CFDIMMCL_00319 5.5e-144 tcyA ET Belongs to the bacterial solute-binding protein 3 family
CFDIMMCL_00320 3.9e-159 bsdA K LysR substrate binding domain
CFDIMMCL_00321 6.4e-102 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
CFDIMMCL_00322 6.3e-284 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
CFDIMMCL_00323 2e-38 bsdD 4.1.1.61 S response to toxic substance
CFDIMMCL_00324 5.2e-78 yclD
CFDIMMCL_00325 3.2e-270 dtpT E amino acid peptide transporter
CFDIMMCL_00326 2.7e-284 yclG M Pectate lyase superfamily protein
CFDIMMCL_00328 4.9e-296 gerKA EG Spore germination protein
CFDIMMCL_00329 1.6e-238 gerKC S spore germination
CFDIMMCL_00330 3.9e-196 gerKB F Spore germination protein
CFDIMMCL_00331 3.4e-255 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFDIMMCL_00332 1.8e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CFDIMMCL_00333 1.2e-143 yxeM M Belongs to the bacterial solute-binding protein 3 family
CFDIMMCL_00334 3.5e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
CFDIMMCL_00335 4.1e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
CFDIMMCL_00336 1.8e-220 yxeP 3.5.1.47 E hydrolase activity
CFDIMMCL_00337 2.8e-257 yxeQ S MmgE/PrpD family
CFDIMMCL_00338 2.4e-124 yclH P ABC transporter
CFDIMMCL_00339 7.9e-242 yclI V ABC transporter (permease) YclI
CFDIMMCL_00340 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CFDIMMCL_00341 2.8e-263 T PhoQ Sensor
CFDIMMCL_00342 4e-79 S aspartate phosphatase
CFDIMMCL_00345 2.6e-255 lysC 2.7.2.4 E Belongs to the aspartokinase family
CFDIMMCL_00346 2.3e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFDIMMCL_00347 3.6e-166 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFDIMMCL_00348 8.1e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
CFDIMMCL_00349 1.9e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
CFDIMMCL_00350 2.7e-250 ycnB EGP Major facilitator Superfamily
CFDIMMCL_00351 1.1e-153 ycnC K Transcriptional regulator
CFDIMMCL_00352 1.4e-136 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
CFDIMMCL_00353 3.6e-45 ycnE S Monooxygenase
CFDIMMCL_00354 8.8e-53 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
CFDIMMCL_00355 2.8e-268 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CFDIMMCL_00356 5.3e-221 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CFDIMMCL_00357 1.4e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CFDIMMCL_00358 3.6e-149 glcU U Glucose uptake
CFDIMMCL_00359 1.1e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CFDIMMCL_00360 3.5e-98 ycnI S protein conserved in bacteria
CFDIMMCL_00361 1.3e-193 ycnJ P protein, homolog of Cu resistance protein CopC
CFDIMMCL_00362 5.8e-43 ycnJ P protein, homolog of Cu resistance protein CopC
CFDIMMCL_00363 5e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
CFDIMMCL_00364 1.6e-55
CFDIMMCL_00365 2.7e-226 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
CFDIMMCL_00366 1.4e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
CFDIMMCL_00367 6.6e-212 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
CFDIMMCL_00368 3.2e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
CFDIMMCL_00370 2.1e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
CFDIMMCL_00371 2.7e-140 ycsF S Belongs to the UPF0271 (lamB) family
CFDIMMCL_00372 4.7e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
CFDIMMCL_00373 1.1e-152 ycsI S Belongs to the D-glutamate cyclase family
CFDIMMCL_00374 5.4e-138 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
CFDIMMCL_00375 9e-192 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
CFDIMMCL_00376 1.1e-131 kipR K Transcriptional regulator
CFDIMMCL_00377 8.4e-119 ycsK E anatomical structure formation involved in morphogenesis
CFDIMMCL_00379 5.1e-56 yczJ S biosynthesis
CFDIMMCL_00380 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
CFDIMMCL_00381 3.1e-175 ydhF S Oxidoreductase
CFDIMMCL_00382 0.0 mtlR K transcriptional regulator, MtlR
CFDIMMCL_00383 4.3e-291 ydaB IQ acyl-CoA ligase
CFDIMMCL_00384 9.7e-163 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CFDIMMCL_00385 9.3e-97 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
CFDIMMCL_00386 1.4e-118 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
CFDIMMCL_00387 1.4e-77 ydaG 1.4.3.5 S general stress protein
CFDIMMCL_00388 5.4e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
CFDIMMCL_00389 2.7e-48 ydzA EGP Major facilitator Superfamily
CFDIMMCL_00390 1.5e-74 lrpC K Transcriptional regulator
CFDIMMCL_00391 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CFDIMMCL_00392 4e-206 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
CFDIMMCL_00393 5.2e-129 ydaK T Diguanylate cyclase, GGDEF domain
CFDIMMCL_00394 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
CFDIMMCL_00395 8.5e-232 ydaM M Glycosyl transferase family group 2
CFDIMMCL_00396 0.0 ydaN S Bacterial cellulose synthase subunit
CFDIMMCL_00397 0.0 ydaO E amino acid
CFDIMMCL_00398 2.2e-78 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
CFDIMMCL_00399 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
CFDIMMCL_00400 2.2e-75 K acetyltransferase
CFDIMMCL_00402 4.7e-14
CFDIMMCL_00403 3.7e-210 S Histidine kinase
CFDIMMCL_00405 3.6e-11
CFDIMMCL_00407 5.1e-80
CFDIMMCL_00408 3.5e-100
CFDIMMCL_00409 7.2e-40
CFDIMMCL_00410 2.4e-226 mntH P H( )-stimulated, divalent metal cation uptake system
CFDIMMCL_00412 6.5e-34 ydaT
CFDIMMCL_00413 5.8e-73 yvaD S Family of unknown function (DUF5360)
CFDIMMCL_00414 4.1e-54 yvaE P Small Multidrug Resistance protein
CFDIMMCL_00415 1.8e-142 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
CFDIMMCL_00417 2.1e-45 ydbB G Cupin domain
CFDIMMCL_00418 6.3e-63 ydbC S Domain of unknown function (DUF4937
CFDIMMCL_00419 6.5e-156 ydbD P Catalase
CFDIMMCL_00420 2.2e-201 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
CFDIMMCL_00421 5.9e-302 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
CFDIMMCL_00422 3.9e-119 dctR T COG4565 Response regulator of citrate malate metabolism
CFDIMMCL_00423 1.7e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CFDIMMCL_00424 3.2e-160 ydbI S AI-2E family transporter
CFDIMMCL_00425 5e-173 ydbJ V ABC transporter, ATP-binding protein
CFDIMMCL_00426 7.4e-130 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
CFDIMMCL_00427 2.1e-52 ydbL
CFDIMMCL_00428 1.2e-208 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
CFDIMMCL_00429 1.5e-10 S Fur-regulated basic protein B
CFDIMMCL_00430 1.1e-60 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CFDIMMCL_00431 5e-82 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CFDIMMCL_00432 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
CFDIMMCL_00433 3.2e-203 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
CFDIMMCL_00434 4.7e-260 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
CFDIMMCL_00435 1.3e-250 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
CFDIMMCL_00436 2.1e-82 ydbS S Bacterial PH domain
CFDIMMCL_00437 1.2e-266 ydbT S Membrane
CFDIMMCL_00438 1.4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
CFDIMMCL_00439 5e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
CFDIMMCL_00440 2.6e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
CFDIMMCL_00441 1.3e-221 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CFDIMMCL_00442 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
CFDIMMCL_00443 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
CFDIMMCL_00444 6.1e-146 rsbR T Positive regulator of sigma-B
CFDIMMCL_00445 1.8e-57 rsbS T antagonist
CFDIMMCL_00446 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
CFDIMMCL_00447 4.6e-188 rsbU 3.1.3.3 KT phosphatase
CFDIMMCL_00448 1.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
CFDIMMCL_00449 2.1e-85 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
CFDIMMCL_00450 1.4e-139 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFDIMMCL_00451 2.3e-110 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
CFDIMMCL_00452 0.0 yhgF K COG2183 Transcriptional accessory protein
CFDIMMCL_00453 1.7e-14
CFDIMMCL_00454 1.3e-59 ydcK S Belongs to the SprT family
CFDIMMCL_00462 8.7e-98 ywrO 1.6.5.2 S Flavodoxin-like fold
CFDIMMCL_00463 3.1e-74 S SnoaL-like polyketide cyclase
CFDIMMCL_00464 4.4e-143 yddR S Zn-dependent hydrolases of the beta-lactamase fold
CFDIMMCL_00465 2.4e-71 lrpA K transcriptional
CFDIMMCL_00466 2.6e-157 S Serine aminopeptidase, S33
CFDIMMCL_00467 7.4e-261 proP EGP Transporter
CFDIMMCL_00468 2.6e-49 ohrR K Transcriptional regulator
CFDIMMCL_00469 5.4e-86 S Domain of unknown function with cystatin-like fold (DUF4467)
CFDIMMCL_00470 1.4e-74 maoC I N-terminal half of MaoC dehydratase
CFDIMMCL_00471 3.8e-65 yyaQ S YjbR
CFDIMMCL_00472 5.1e-75 ywnA K Transcriptional regulator
CFDIMMCL_00473 5.3e-113 ywnB S NAD(P)H-binding
CFDIMMCL_00474 4.9e-102 K Bacterial regulatory proteins, tetR family
CFDIMMCL_00475 9.1e-133 C Enoyl-(Acyl carrier protein) reductase
CFDIMMCL_00476 6.8e-184 1.1.1.1 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
CFDIMMCL_00477 2.4e-178 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
CFDIMMCL_00478 6.9e-56 K Transcriptional regulator
CFDIMMCL_00479 1e-198 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
CFDIMMCL_00480 1.4e-30 cspL K Cold shock
CFDIMMCL_00481 1.2e-79 carD K Transcription factor
CFDIMMCL_00482 9.2e-40 yrkD S protein conserved in bacteria
CFDIMMCL_00483 1.1e-83 yrkE O DsrE/DsrF/DrsH-like family
CFDIMMCL_00484 3.4e-64 P Rhodanese Homology Domain
CFDIMMCL_00485 1.8e-101 yrkF OP Belongs to the sulfur carrier protein TusA family
CFDIMMCL_00486 2.2e-199 yrkH P Rhodanese Homology Domain
CFDIMMCL_00487 5.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
CFDIMMCL_00488 3.5e-119 yrkJ S membrane transporter protein
CFDIMMCL_00489 2e-126 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
CFDIMMCL_00490 2.3e-107 S Protein of unknown function (DUF2812)
CFDIMMCL_00491 3.4e-52 K Transcriptional regulator PadR-like family
CFDIMMCL_00492 3e-156 ybfA 3.4.15.5 K FR47-like protein
CFDIMMCL_00493 1.8e-237 ybfB G COG0477 Permeases of the major facilitator superfamily
CFDIMMCL_00494 2.3e-184 S Patatin-like phospholipase
CFDIMMCL_00495 1.3e-84 S DinB superfamily
CFDIMMCL_00496 8.8e-65 G Cupin domain
CFDIMMCL_00499 1.6e-268 ygaK C COG0277 FAD FMN-containing dehydrogenases
CFDIMMCL_00500 1.5e-79 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CFDIMMCL_00501 1.8e-170 czcD P COG1230 Co Zn Cd efflux system component
CFDIMMCL_00502 4.4e-202 trkA P Oxidoreductase
CFDIMMCL_00504 7e-103 yrkC G Cupin domain
CFDIMMCL_00506 2.6e-88 ykkA S Protein of unknown function (DUF664)
CFDIMMCL_00507 1.6e-150 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
CFDIMMCL_00509 2.4e-200 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
CFDIMMCL_00510 9.3e-57 ydeH
CFDIMMCL_00511 7.5e-85 F nucleoside 2-deoxyribosyltransferase
CFDIMMCL_00512 1.3e-195 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CFDIMMCL_00513 1.2e-148 Q ubiE/COQ5 methyltransferase family
CFDIMMCL_00514 2.6e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
CFDIMMCL_00515 1.4e-234 3.1.3.41 G Haloacid dehalogenase-like hydrolase
CFDIMMCL_00516 2.4e-170 S Sodium Bile acid symporter family
CFDIMMCL_00517 4e-203 adhA 1.1.1.1 C alcohol dehydrogenase
CFDIMMCL_00518 3.6e-67 yraB K helix_turn_helix, mercury resistance
CFDIMMCL_00519 1.4e-90 mleN_2 C antiporter
CFDIMMCL_00520 3.9e-128 mleN_2 C antiporter
CFDIMMCL_00521 5.8e-266 K helix_turn_helix gluconate operon transcriptional repressor
CFDIMMCL_00522 8.4e-116 paiB K Transcriptional regulator
CFDIMMCL_00524 2.8e-24 ksgA1 I Ribosomal RNA adenine dimethylase
CFDIMMCL_00525 4.4e-80 ksgA1 I Ribosomal RNA adenine dimethylase
CFDIMMCL_00526 5.4e-124 T Transcriptional regulator
CFDIMMCL_00527 1.1e-192 T PhoQ Sensor
CFDIMMCL_00528 2.8e-106 S SNARE associated Golgi protein
CFDIMMCL_00529 2.7e-187 ydeR EGP Major facilitator Superfamily
CFDIMMCL_00530 4.5e-103 ydeS K Transcriptional regulator
CFDIMMCL_00531 3.3e-158 ydeK EG -transporter
CFDIMMCL_00532 3.9e-270 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CFDIMMCL_00533 1.9e-49 yraD M Spore coat protein
CFDIMMCL_00534 7.5e-26 yraE
CFDIMMCL_00535 2.2e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
CFDIMMCL_00536 9.9e-64 yraF M Spore coat protein
CFDIMMCL_00537 6.9e-37 yraG
CFDIMMCL_00538 1.8e-221 ydfH 2.7.13.3 T Histidine kinase
CFDIMMCL_00539 3.7e-111 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CFDIMMCL_00540 0.0 ydfJ S drug exporters of the RND superfamily
CFDIMMCL_00541 9.1e-137 puuD S Peptidase C26
CFDIMMCL_00542 2.6e-302 expZ S ABC transporter
CFDIMMCL_00543 5.9e-102 ynaD J Acetyltransferase (GNAT) domain
CFDIMMCL_00544 2.5e-150 S Uncharacterized protein conserved in bacteria (DUF2179)
CFDIMMCL_00545 1.6e-197 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
CFDIMMCL_00546 7.9e-211 tcaB EGP Major facilitator Superfamily
CFDIMMCL_00547 1.2e-227 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CFDIMMCL_00548 2.7e-157 K Helix-turn-helix XRE-family like proteins
CFDIMMCL_00549 1.3e-123 ydhB S membrane transporter protein
CFDIMMCL_00550 2.4e-83 bltD 2.3.1.57 K FR47-like protein
CFDIMMCL_00551 5.7e-152 bltR K helix_turn_helix, mercury resistance
CFDIMMCL_00552 2.3e-151 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
CFDIMMCL_00553 1.1e-115 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
CFDIMMCL_00554 2.3e-147 ycgJ_1 Q ubiE/COQ5 methyltransferase family
CFDIMMCL_00555 3e-156 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
CFDIMMCL_00556 3.1e-21 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
CFDIMMCL_00557 1.3e-120 ydhC K FCD
CFDIMMCL_00558 1.7e-229 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
CFDIMMCL_00561 1.6e-268 pbpE V Beta-lactamase
CFDIMMCL_00563 2.5e-98 ydhK M Protein of unknown function (DUF1541)
CFDIMMCL_00564 1.2e-195 pbuE EGP Major facilitator Superfamily
CFDIMMCL_00565 1.3e-133 ydhQ K UTRA
CFDIMMCL_00566 1.4e-119 K FCD
CFDIMMCL_00567 7.4e-217 yeaN P COG2807 Cyanate permease
CFDIMMCL_00568 2.6e-49 sugE P Small Multidrug Resistance protein
CFDIMMCL_00569 2.3e-51 ykkC P Small Multidrug Resistance protein
CFDIMMCL_00570 5.3e-104 yvdT K Transcriptional regulator
CFDIMMCL_00571 9.3e-297 yveA E amino acid
CFDIMMCL_00572 3.2e-166 ydhU P Catalase
CFDIMMCL_00573 6.4e-84 yndB S Activator of Hsp90 ATPase homolog 1-like protein
CFDIMMCL_00574 4.7e-185 yhfP 1.1.1.1 C Quinone oxidoreductase
CFDIMMCL_00575 1.2e-253 iolT EGP Major facilitator Superfamily
CFDIMMCL_00578 3.4e-39 S COG NOG14552 non supervised orthologous group
CFDIMMCL_00581 7.8e-08
CFDIMMCL_00583 1.4e-186 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CFDIMMCL_00584 4.1e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
CFDIMMCL_00585 1.3e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
CFDIMMCL_00586 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
CFDIMMCL_00587 2.7e-191 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CFDIMMCL_00588 2.1e-172 ydiF S ABC transporter
CFDIMMCL_00589 6.7e-128 ydiF S ABC transporter
CFDIMMCL_00590 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
CFDIMMCL_00591 3e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CFDIMMCL_00592 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
CFDIMMCL_00593 1.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CFDIMMCL_00594 1.7e-27 ydiK S Domain of unknown function (DUF4305)
CFDIMMCL_00595 2.5e-127 ydiL S CAAX protease self-immunity
CFDIMMCL_00596 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CFDIMMCL_00597 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
CFDIMMCL_00598 0.0 ybfG 3.2.1.132 M Putative peptidoglycan binding domain
CFDIMMCL_00601 4.2e-65
CFDIMMCL_00602 0.0 K NB-ARC domain
CFDIMMCL_00603 4.5e-202 gutB 1.1.1.14 E Dehydrogenase
CFDIMMCL_00604 2.3e-251 gutA G MFS/sugar transport protein
CFDIMMCL_00605 2.5e-175 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
CFDIMMCL_00606 6.2e-30 yjdJ S Domain of unknown function (DUF4306)
CFDIMMCL_00607 2.7e-115 pspA KT Phage shock protein A
CFDIMMCL_00608 4.7e-180 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CFDIMMCL_00609 3.3e-122 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
CFDIMMCL_00610 1.9e-157 ydjI S virion core protein (lumpy skin disease virus)
CFDIMMCL_00611 0.0 yrhL I Acyltransferase family
CFDIMMCL_00612 1.2e-147 rsiV S Protein of unknown function (DUF3298)
CFDIMMCL_00613 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
CFDIMMCL_00614 1.8e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
CFDIMMCL_00615 1.4e-62 ydjM M Lytic transglycolase
CFDIMMCL_00616 9.4e-136 ydjN U Involved in the tonB-independent uptake of proteins
CFDIMMCL_00618 7.2e-35 ydjO S Cold-inducible protein YdjO
CFDIMMCL_00619 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
CFDIMMCL_00620 4.4e-237 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
CFDIMMCL_00621 5.8e-155 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CFDIMMCL_00622 3.5e-177 yeaC S COG0714 MoxR-like ATPases
CFDIMMCL_00623 1.6e-216 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
CFDIMMCL_00624 0.0 yebA E COG1305 Transglutaminase-like enzymes
CFDIMMCL_00625 2.2e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
CFDIMMCL_00626 7.8e-94 sigV K Belongs to the sigma-70 factor family. ECF subfamily
CFDIMMCL_00627 8.6e-273 S Domain of unknown function (DUF4179)
CFDIMMCL_00628 6.2e-209 pbuG S permease
CFDIMMCL_00629 3e-134 yebC M Membrane
CFDIMMCL_00631 3.1e-93 yebE S UPF0316 protein
CFDIMMCL_00632 5.5e-29 yebG S NETI protein
CFDIMMCL_00633 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CFDIMMCL_00634 7.2e-225 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CFDIMMCL_00635 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CFDIMMCL_00636 2.2e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
CFDIMMCL_00637 2.2e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFDIMMCL_00638 2.3e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFDIMMCL_00639 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFDIMMCL_00640 2.1e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CFDIMMCL_00641 4.2e-184 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
CFDIMMCL_00642 2.2e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CFDIMMCL_00643 4.1e-289 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
CFDIMMCL_00644 6.1e-238 purD 6.3.4.13 F Belongs to the GARS family
CFDIMMCL_00645 1.2e-25 S Protein of unknown function (DUF2892)
CFDIMMCL_00646 0.0 yerA 3.5.4.2 F adenine deaminase
CFDIMMCL_00647 1.4e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
CFDIMMCL_00648 2.4e-50 yerC S protein conserved in bacteria
CFDIMMCL_00649 7.9e-304 yerD 1.4.7.1 E Belongs to the glutamate synthase family
CFDIMMCL_00650 6.2e-128 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
CFDIMMCL_00651 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
CFDIMMCL_00652 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CFDIMMCL_00653 1.4e-223 camS S COG4851 Protein involved in sex pheromone biosynthesis
CFDIMMCL_00654 7.5e-199 yerI S homoserine kinase type II (protein kinase fold)
CFDIMMCL_00655 8.8e-122 sapB S MgtC SapB transporter
CFDIMMCL_00656 3.7e-263 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CFDIMMCL_00657 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFDIMMCL_00658 3.4e-255 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
CFDIMMCL_00659 5.2e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFDIMMCL_00660 9.6e-155 yerO K Transcriptional regulator
CFDIMMCL_00661 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFDIMMCL_00662 6.7e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
CFDIMMCL_00663 9.9e-258 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CFDIMMCL_00664 1.8e-300 hsdM 2.1.1.72 V Type I restriction-modification system
CFDIMMCL_00665 4e-234 3.1.21.3 V Type I restriction modification DNA specificity domain
CFDIMMCL_00666 8.2e-143 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
CFDIMMCL_00667 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
CFDIMMCL_00671 1.5e-18 V Domain of unknown function (DUF3578)
CFDIMMCL_00672 4.3e-194 V Domain of unknown function (DUF3578)
CFDIMMCL_00673 2.6e-91 S Protein of unknown function, DUF600
CFDIMMCL_00674 4.5e-82 S Protein of unknown function, DUF600
CFDIMMCL_00675 2.9e-84 S Protein of unknown function, DUF600
CFDIMMCL_00676 0.0 yobL L nucleic acid phosphodiester bond hydrolysis
CFDIMMCL_00677 9.4e-127 yeeN K transcriptional regulatory protein
CFDIMMCL_00679 4.1e-45 cotJA S Spore coat associated protein JA (CotJA)
CFDIMMCL_00680 3.3e-45 cotJB S CotJB protein
CFDIMMCL_00681 8.9e-104 cotJC P Spore Coat
CFDIMMCL_00682 1.6e-99 yesJ K Acetyltransferase (GNAT) family
CFDIMMCL_00684 8.7e-122 yetF S membrane
CFDIMMCL_00685 3.3e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
CFDIMMCL_00686 4e-65 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CFDIMMCL_00687 1.8e-156 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CFDIMMCL_00688 1.2e-22 yezD S Uncharacterized small protein (DUF2292)
CFDIMMCL_00689 1.8e-55 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
CFDIMMCL_00690 8.2e-106 yetJ S Belongs to the BI1 family
CFDIMMCL_00691 1.3e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
CFDIMMCL_00692 2.8e-210 yetM CH FAD binding domain
CFDIMMCL_00693 2.6e-197 yetN S Protein of unknown function (DUF3900)
CFDIMMCL_00694 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
CFDIMMCL_00696 3.1e-50 MA20_23570 K Winged helix DNA-binding domain
CFDIMMCL_00697 6.7e-167 V ATPases associated with a variety of cellular activities
CFDIMMCL_00698 1.7e-126 V ABC-2 type transporter
CFDIMMCL_00699 6.4e-75 S protein homooligomerization
CFDIMMCL_00700 6.4e-128
CFDIMMCL_00701 1.6e-193 S ATP diphosphatase activity
CFDIMMCL_00702 1e-267 S YcaO cyclodehydratase, ATP-ad Mg2+-binding
CFDIMMCL_00703 1e-153 sagB C Nitroreductase family
CFDIMMCL_00704 1e-114 S CAAX protease self-immunity
CFDIMMCL_00705 1.1e-147 2.1.1.163, 2.1.1.201 Q methyltransferase
CFDIMMCL_00707 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
CFDIMMCL_00708 1.2e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
CFDIMMCL_00709 2.4e-172 yfnG 4.2.1.45 M dehydratase
CFDIMMCL_00710 1.4e-180 yfnF M Nucleotide-diphospho-sugar transferase
CFDIMMCL_00711 2.1e-224 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
CFDIMMCL_00712 2.5e-188 yfnD M Nucleotide-diphospho-sugar transferase
CFDIMMCL_00713 3.6e-219 fsr P COG0477 Permeases of the major facilitator superfamily
CFDIMMCL_00714 4.2e-248 yfnA E amino acid
CFDIMMCL_00715 4.1e-278 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CFDIMMCL_00716 9.8e-115 yfmS NT chemotaxis protein
CFDIMMCL_00717 5.2e-167 IQ Enoyl-(Acyl carrier protein) reductase
CFDIMMCL_00718 1.6e-210 M COG0463 Glycosyltransferases involved in cell wall biogenesis
CFDIMMCL_00719 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
CFDIMMCL_00720 6.2e-70 yfmP K transcriptional
CFDIMMCL_00721 2.1e-208 yfmO EGP Major facilitator Superfamily
CFDIMMCL_00722 1.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
CFDIMMCL_00723 7.7e-208 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
CFDIMMCL_00724 3.6e-19 yfmK 2.3.1.128 K acetyltransferase
CFDIMMCL_00725 6.3e-33 yfmK 2.3.1.128 K acetyltransferase
CFDIMMCL_00726 2e-191 yfmJ S N-terminal domain of oxidoreductase
CFDIMMCL_00727 1.7e-24 S Protein of unknown function (DUF3212)
CFDIMMCL_00728 1.3e-57 yflT S Heat induced stress protein YflT
CFDIMMCL_00729 8.2e-243 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
CFDIMMCL_00730 3.5e-234 yflS P Sodium:sulfate symporter transmembrane region
CFDIMMCL_00731 2.8e-35 Q PFAM Collagen triple helix
CFDIMMCL_00732 1.6e-76 Q PFAM Collagen triple helix
CFDIMMCL_00733 8.9e-141 Q calcium- and calmodulin-responsive adenylate cyclase activity
CFDIMMCL_00734 4.8e-87 M1-820 Q Collagen triple helix repeat (20 copies)
CFDIMMCL_00735 6.5e-277 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
CFDIMMCL_00736 9.5e-121 citT T response regulator
CFDIMMCL_00737 8.3e-179 yflP S Tripartite tricarboxylate transporter family receptor
CFDIMMCL_00738 3.8e-227 citM C Citrate transporter
CFDIMMCL_00739 7.9e-151 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
CFDIMMCL_00740 1.4e-219 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CFDIMMCL_00741 7.6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
CFDIMMCL_00742 2.3e-124 yflK S protein conserved in bacteria
CFDIMMCL_00743 1.5e-14 yflJ S Protein of unknown function (DUF2639)
CFDIMMCL_00744 7e-19 yflI
CFDIMMCL_00745 3.1e-50 yflH S Protein of unknown function (DUF3243)
CFDIMMCL_00746 3.2e-138 map 3.4.11.18 E Methionine aminopeptidase
CFDIMMCL_00747 1.3e-246 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
CFDIMMCL_00748 2.2e-73 yfmQ S Uncharacterised protein from bacillus cereus group
CFDIMMCL_00749 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
CFDIMMCL_00750 7.8e-64 yhdN S Domain of unknown function (DUF1992)
CFDIMMCL_00751 1.2e-79 cotP O Belongs to the small heat shock protein (HSP20) family
CFDIMMCL_00752 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
CFDIMMCL_00753 1.2e-39 ydgB S Spore germination protein gerPA/gerPF
CFDIMMCL_00754 6.6e-241 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CFDIMMCL_00755 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
CFDIMMCL_00756 9e-130 treR K transcriptional
CFDIMMCL_00757 1.2e-123 yfkO C nitroreductase
CFDIMMCL_00758 4.2e-125 yibF S YibE/F-like protein
CFDIMMCL_00759 5.2e-204 yibE S YibE/F-like protein
CFDIMMCL_00761 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
CFDIMMCL_00762 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
CFDIMMCL_00763 3e-187 K helix_turn _helix lactose operon repressor
CFDIMMCL_00764 1.1e-164 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CFDIMMCL_00765 7.3e-138 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
CFDIMMCL_00766 1.3e-194 ydiM EGP Major facilitator Superfamily
CFDIMMCL_00767 7.1e-30 yfkK S Belongs to the UPF0435 family
CFDIMMCL_00768 1.4e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CFDIMMCL_00769 2e-52 yfkI S gas vesicle protein
CFDIMMCL_00770 6.8e-145 yihY S Belongs to the UPF0761 family
CFDIMMCL_00771 2.5e-07
CFDIMMCL_00772 1.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
CFDIMMCL_00773 1.3e-185 cax P COG0387 Ca2 H antiporter
CFDIMMCL_00774 1.9e-144 yfkD S YfkD-like protein
CFDIMMCL_00775 3.3e-147 yfkC M Mechanosensitive ion channel
CFDIMMCL_00776 2.7e-221 yfkA S YfkB-like domain
CFDIMMCL_00777 4.9e-27 yfjT
CFDIMMCL_00778 1.8e-155 pdaA G deacetylase
CFDIMMCL_00779 7.7e-152 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
CFDIMMCL_00780 5.4e-33
CFDIMMCL_00781 1.7e-184 corA P Mediates influx of magnesium ions
CFDIMMCL_00782 7.2e-166 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CFDIMMCL_00783 5.6e-269 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CFDIMMCL_00784 2.7e-193 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CFDIMMCL_00785 1.3e-95 yfjM S Psort location Cytoplasmic, score
CFDIMMCL_00786 7.5e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
CFDIMMCL_00787 5e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
CFDIMMCL_00788 8.6e-218 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CFDIMMCL_00789 1.5e-258 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
CFDIMMCL_00790 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
CFDIMMCL_00791 4.2e-15 sspH S Belongs to the SspH family
CFDIMMCL_00792 1.2e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
CFDIMMCL_00793 1e-139 glvR F Helix-turn-helix domain, rpiR family
CFDIMMCL_00794 1e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CFDIMMCL_00795 4.6e-271 yobO M COG5434 Endopolygalacturonase
CFDIMMCL_00796 1.2e-185 yobO M COG5434 Endopolygalacturonase
CFDIMMCL_00797 0.0 yfiB3 V ABC transporter
CFDIMMCL_00798 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
CFDIMMCL_00799 2.4e-63 mhqP S DoxX
CFDIMMCL_00800 1.1e-161 yfiE 1.13.11.2 S glyoxalase
CFDIMMCL_00801 1.5e-172 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
CFDIMMCL_00802 1.7e-96 padR K transcriptional
CFDIMMCL_00803 6.5e-113 1.6.5.2 S NADPH-dependent FMN reductase
CFDIMMCL_00804 2.5e-184 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
CFDIMMCL_00805 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
CFDIMMCL_00806 1.5e-45 yrdF K ribonuclease inhibitor
CFDIMMCL_00807 2.7e-102 yfiT S Belongs to the metal hydrolase YfiT family
CFDIMMCL_00808 6.4e-293 yfiU EGP Major facilitator Superfamily
CFDIMMCL_00809 5.6e-83 yfiV K transcriptional
CFDIMMCL_00810 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CFDIMMCL_00811 2.7e-168 yfhB 5.3.3.17 S PhzF family
CFDIMMCL_00812 3.3e-106 yfhC C nitroreductase
CFDIMMCL_00813 2.1e-25 yfhD S YfhD-like protein
CFDIMMCL_00815 3.3e-169 yfhF S nucleoside-diphosphate sugar epimerase
CFDIMMCL_00816 1e-61 recX 2.4.1.337 GT4 S Modulates RecA activity
CFDIMMCL_00817 5.6e-36 recX 2.4.1.337 GT4 S Modulates RecA activity
CFDIMMCL_00818 8.8e-53 yfhH S Protein of unknown function (DUF1811)
CFDIMMCL_00819 1.2e-206 yfhI EGP Major facilitator Superfamily
CFDIMMCL_00821 9.6e-169 mpr 3.4.21.19 M Belongs to the peptidase S1B family
CFDIMMCL_00822 4.4e-45 yfhJ S WVELL protein
CFDIMMCL_00823 1.8e-95 batE T Bacterial SH3 domain homologues
CFDIMMCL_00824 1.4e-35 yfhL S SdpI/YhfL protein family
CFDIMMCL_00825 1.5e-171 yfhM S Alpha/beta hydrolase family
CFDIMMCL_00826 4.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
CFDIMMCL_00827 0.0 yfhO S Bacterial membrane protein YfhO
CFDIMMCL_00828 2.1e-185 yfhP S membrane-bound metal-dependent
CFDIMMCL_00829 1.1e-206 mutY L A G-specific
CFDIMMCL_00830 8.2e-37 yfhS
CFDIMMCL_00831 5.8e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CFDIMMCL_00833 1.5e-37 ygaB S YgaB-like protein
CFDIMMCL_00834 2.2e-104 ygaC J Belongs to the UPF0374 family
CFDIMMCL_00835 2.5e-306 ygaD V ABC transporter
CFDIMMCL_00836 1.1e-179 ygaE S Membrane
CFDIMMCL_00837 6.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
CFDIMMCL_00838 1.1e-86 bcp 1.11.1.15 O Peroxiredoxin
CFDIMMCL_00839 1.8e-80 perR P Belongs to the Fur family
CFDIMMCL_00840 1.5e-56 ygzB S UPF0295 protein
CFDIMMCL_00841 3.7e-165 ygxA S Nucleotidyltransferase-like
CFDIMMCL_00842 3.4e-39 S COG NOG14552 non supervised orthologous group
CFDIMMCL_00849 7.8e-08
CFDIMMCL_00857 1.6e-08
CFDIMMCL_00861 5.5e-289 C Na+/H+ antiporter family
CFDIMMCL_00862 1.2e-134 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
CFDIMMCL_00863 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CFDIMMCL_00864 3e-267 ygaK C Berberine and berberine like
CFDIMMCL_00867 2.1e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
CFDIMMCL_00868 7.3e-188 S Amidohydrolase
CFDIMMCL_00869 1.4e-141 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
CFDIMMCL_00870 4.8e-182 ssuA M Sulfonate ABC transporter
CFDIMMCL_00871 3.6e-146 ssuC P ABC transporter (permease)
CFDIMMCL_00872 1.4e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
CFDIMMCL_00873 1.2e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CFDIMMCL_00874 3e-81 ygaO
CFDIMMCL_00875 4.8e-23 K Transcriptional regulator
CFDIMMCL_00877 1.6e-114 yhzB S B3/4 domain
CFDIMMCL_00878 8.4e-226 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CFDIMMCL_00879 4.8e-176 yhbB S Putative amidase domain
CFDIMMCL_00880 6.9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
CFDIMMCL_00881 3.5e-109 yhbD K Protein of unknown function (DUF4004)
CFDIMMCL_00882 8.6e-64 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
CFDIMMCL_00883 3.5e-65 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
CFDIMMCL_00885 0.0 prkA T Ser protein kinase
CFDIMMCL_00886 1.2e-216 yhbH S Belongs to the UPF0229 family
CFDIMMCL_00887 4.6e-74 yhbI K DNA-binding transcription factor activity
CFDIMMCL_00888 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
CFDIMMCL_00889 6.4e-285 yhcA EGP Major facilitator Superfamily
CFDIMMCL_00890 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
CFDIMMCL_00891 3.8e-55 yhcC
CFDIMMCL_00892 9.6e-53
CFDIMMCL_00893 2.5e-62 yhcF K Transcriptional regulator
CFDIMMCL_00894 1.6e-126 yhcG V ABC transporter, ATP-binding protein
CFDIMMCL_00895 4.1e-167 yhcH V ABC transporter, ATP-binding protein
CFDIMMCL_00896 5.1e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
CFDIMMCL_00897 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
CFDIMMCL_00898 3.5e-149 metQ M Belongs to the nlpA lipoprotein family
CFDIMMCL_00899 4.4e-197 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
CFDIMMCL_00900 2.2e-222 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CFDIMMCL_00901 4.8e-57 yhcM
CFDIMMCL_00902 3.9e-85 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
CFDIMMCL_00903 3.6e-156 yhcP
CFDIMMCL_00904 3.7e-117 yhcQ M Spore coat protein
CFDIMMCL_00905 0.0 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
CFDIMMCL_00906 1.6e-108 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
CFDIMMCL_00907 4.9e-173 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CFDIMMCL_00908 1.3e-69 yhcU S Family of unknown function (DUF5365)
CFDIMMCL_00909 2.6e-68 yhcV S COG0517 FOG CBS domain
CFDIMMCL_00910 4.9e-125 yhcW 5.4.2.6 S hydrolase
CFDIMMCL_00911 1.7e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
CFDIMMCL_00912 1.7e-262 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CFDIMMCL_00913 8.9e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CFDIMMCL_00914 1.2e-149 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
CFDIMMCL_00915 1.9e-294 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CFDIMMCL_00916 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CFDIMMCL_00917 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
CFDIMMCL_00918 1.8e-209 yhcY 2.7.13.3 T Histidine kinase
CFDIMMCL_00919 1.5e-112 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CFDIMMCL_00920 4.6e-91 azr 1.7.1.6 S NADPH-dependent FMN reductase
CFDIMMCL_00921 2.5e-39 yhdB S YhdB-like protein
CFDIMMCL_00922 1.1e-53 yhdC S Protein of unknown function (DUF3889)
CFDIMMCL_00923 1.6e-218 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
CFDIMMCL_00924 1.9e-74 nsrR K Transcriptional regulator
CFDIMMCL_00925 1.4e-257 ygxB M Conserved TM helix
CFDIMMCL_00926 1.2e-271 ycgB S Stage V sporulation protein R
CFDIMMCL_00927 6.2e-260 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
CFDIMMCL_00928 3.3e-128 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
CFDIMMCL_00929 9e-164 citR K Transcriptional regulator
CFDIMMCL_00930 1.3e-207 citA 2.3.3.1 C Belongs to the citrate synthase family
CFDIMMCL_00931 5.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CFDIMMCL_00932 4.1e-251 yhdG E amino acid
CFDIMMCL_00933 2e-199 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
CFDIMMCL_00934 8.1e-45 yhdK S Sigma-M inhibitor protein
CFDIMMCL_00935 1.3e-201 yhdL S Sigma factor regulator N-terminal
CFDIMMCL_00936 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
CFDIMMCL_00937 5.1e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
CFDIMMCL_00938 4.3e-242 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
CFDIMMCL_00939 4.3e-71 cueR K transcriptional
CFDIMMCL_00940 3.5e-227 yhdR 2.6.1.1 E Aminotransferase
CFDIMMCL_00941 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CFDIMMCL_00942 2.9e-257 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
CFDIMMCL_00943 8.5e-52 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CFDIMMCL_00944 1.7e-66 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CFDIMMCL_00945 2.8e-131 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
CFDIMMCL_00947 1.6e-205 yhdY M Mechanosensitive ion channel
CFDIMMCL_00948 4.5e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
CFDIMMCL_00949 4.9e-159 yheN G deacetylase
CFDIMMCL_00950 4.3e-155 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
CFDIMMCL_00951 4.6e-88 pksA K Transcriptional regulator
CFDIMMCL_00952 2e-87 ymcC S Membrane
CFDIMMCL_00953 4.3e-86 T universal stress protein
CFDIMMCL_00955 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
CFDIMMCL_00956 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
CFDIMMCL_00957 1.7e-88 yheG GM NAD(P)H-binding
CFDIMMCL_00959 5.8e-29 sspB S spore protein
CFDIMMCL_00960 1.7e-36 yheE S Family of unknown function (DUF5342)
CFDIMMCL_00961 1.1e-261 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
CFDIMMCL_00962 4.8e-215 yheC HJ YheC/D like ATP-grasp
CFDIMMCL_00963 5.9e-208 yheB S Belongs to the UPF0754 family
CFDIMMCL_00964 4e-54 yheA S Belongs to the UPF0342 family
CFDIMMCL_00965 1.2e-205 yhaZ L DNA alkylation repair enzyme
CFDIMMCL_00966 1.9e-158 yhaX S haloacid dehalogenase-like hydrolase
CFDIMMCL_00967 9.3e-294 hemZ H coproporphyrinogen III oxidase
CFDIMMCL_00968 2.8e-253 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
CFDIMMCL_00969 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
CFDIMMCL_00971 2.5e-138 yhaR 5.3.3.18 I enoyl-CoA hydratase
CFDIMMCL_00972 7.3e-15 S YhzD-like protein
CFDIMMCL_00973 2.5e-32 yhaQ S ABC transporter, ATP-binding protein
CFDIMMCL_00974 7.6e-126 yhaQ S ABC transporter, ATP-binding protein
CFDIMMCL_00975 1.9e-207 yhaP CP COG1668 ABC-type Na efflux pump, permease component
CFDIMMCL_00976 9.1e-239 yhaO L DNA repair exonuclease
CFDIMMCL_00977 0.0 yhaN L AAA domain
CFDIMMCL_00978 9e-178 yhaM L Shows a 3'-5' exoribonuclease activity
CFDIMMCL_00979 1.6e-32 yhaL S Sporulation protein YhaL
CFDIMMCL_00980 3.3e-123 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
CFDIMMCL_00981 7e-95 yhaK S Putative zincin peptidase
CFDIMMCL_00982 9.9e-55 yhaI S Protein of unknown function (DUF1878)
CFDIMMCL_00983 8.6e-113 hpr K Negative regulator of protease production and sporulation
CFDIMMCL_00984 6.2e-39 yhaH S YtxH-like protein
CFDIMMCL_00985 2e-17
CFDIMMCL_00986 2.9e-77 trpP S Tryptophan transporter TrpP
CFDIMMCL_00987 1.3e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CFDIMMCL_00988 2.4e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
CFDIMMCL_00989 1.1e-135 ecsA V transporter (ATP-binding protein)
CFDIMMCL_00990 1.7e-221 ecsB U ABC transporter
CFDIMMCL_00991 3e-125 ecsC S EcsC protein family
CFDIMMCL_00992 2.2e-226 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
CFDIMMCL_00993 6.1e-126 yhfA C membrane
CFDIMMCL_00994 5.8e-91 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
CFDIMMCL_00995 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CFDIMMCL_00996 3e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CFDIMMCL_00997 2.5e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
CFDIMMCL_00998 1.4e-275 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CFDIMMCL_00999 3.2e-101 yhgD K Transcriptional regulator
CFDIMMCL_01000 6.5e-278 yhgE S YhgE Pip N-terminal domain protein
CFDIMMCL_01001 3.3e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CFDIMMCL_01003 7.8e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
CFDIMMCL_01004 3.4e-228 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CFDIMMCL_01005 1.5e-140 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
CFDIMMCL_01006 3.1e-189 lplJ 6.3.1.20 H Lipoate-protein ligase
CFDIMMCL_01007 8.2e-114 yhfK GM NmrA-like family
CFDIMMCL_01008 6.2e-301 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
CFDIMMCL_01009 8.7e-66 yhfM
CFDIMMCL_01010 6.1e-13 yhfN 3.4.24.84 O Peptidase M48
CFDIMMCL_01011 3.4e-180 yhfN 3.4.24.84 O Peptidase M48
CFDIMMCL_01012 4.3e-206 aprE 3.4.21.62 O Belongs to the peptidase S8 family
CFDIMMCL_01013 1.5e-156 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
CFDIMMCL_01014 3.6e-105 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
CFDIMMCL_01015 3.8e-204 vraB 2.3.1.9 I Belongs to the thiolase family
CFDIMMCL_01016 5.4e-283 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
CFDIMMCL_01017 9.3e-90 bioY S BioY family
CFDIMMCL_01018 1e-200 hemAT NT chemotaxis protein
CFDIMMCL_01019 3.9e-300 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
CFDIMMCL_01020 3.8e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CFDIMMCL_01021 1.3e-32 yhzC S IDEAL
CFDIMMCL_01022 1.9e-109 comK K Competence transcription factor
CFDIMMCL_01023 3.9e-68 frataxin S Domain of unknown function (DU1801)
CFDIMMCL_01024 3.9e-68 frataxin S Domain of unknown function (DU1801)
CFDIMMCL_01025 1.3e-93 mepB S MepB protein
CFDIMMCL_01026 1.9e-127 yrpD S Domain of unknown function, YrpD
CFDIMMCL_01027 1.6e-42 yhjA S Excalibur calcium-binding domain
CFDIMMCL_01028 3.9e-51 S Belongs to the UPF0145 family
CFDIMMCL_01029 1.3e-268 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CFDIMMCL_01030 1.4e-27 yhjC S Protein of unknown function (DUF3311)
CFDIMMCL_01031 1.7e-60 yhjD
CFDIMMCL_01032 4.8e-111 yhjE S SNARE associated Golgi protein
CFDIMMCL_01033 9.2e-92 sipV 3.4.21.89 U Belongs to the peptidase S26 family
CFDIMMCL_01034 3e-281 yhjG CH FAD binding domain
CFDIMMCL_01035 5.8e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
CFDIMMCL_01036 5.1e-191 abrB S membrane
CFDIMMCL_01037 1.1e-209 blt EGP Major facilitator Superfamily
CFDIMMCL_01038 4.5e-109 K QacR-like protein, C-terminal region
CFDIMMCL_01039 2.6e-94 yhjR S Rubrerythrin
CFDIMMCL_01040 1.6e-126 ydfS S Protein of unknown function (DUF421)
CFDIMMCL_01041 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
CFDIMMCL_01042 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
CFDIMMCL_01043 3e-223 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
CFDIMMCL_01044 0.0 sbcC L COG0419 ATPase involved in DNA repair
CFDIMMCL_01045 1.3e-50 yisB V COG1403 Restriction endonuclease
CFDIMMCL_01046 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
CFDIMMCL_01047 1.9e-65 gerPE S Spore germination protein GerPE
CFDIMMCL_01048 3.1e-23 gerPD S Spore germination protein
CFDIMMCL_01049 1.4e-62 gerPC S Spore germination protein
CFDIMMCL_01050 6.2e-35 gerPB S cell differentiation
CFDIMMCL_01051 8.4e-34 gerPA S Spore germination protein
CFDIMMCL_01052 5e-07 yisI S Spo0E like sporulation regulatory protein
CFDIMMCL_01053 1.3e-173 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
CFDIMMCL_01054 1.1e-59 yisL S UPF0344 protein
CFDIMMCL_01055 1.3e-99 yisN S Protein of unknown function (DUF2777)
CFDIMMCL_01056 0.0 asnO 6.3.5.4 E Asparagine synthase
CFDIMMCL_01057 6.7e-136 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
CFDIMMCL_01058 1.5e-245 yisQ V Mate efflux family protein
CFDIMMCL_01059 6.3e-162 yisR K Transcriptional regulator
CFDIMMCL_01060 1.3e-90 yisT S DinB family
CFDIMMCL_01061 1.2e-72 mcbG S Pentapeptide repeats (9 copies)
CFDIMMCL_01062 6.2e-81 yjcF S Acetyltransferase (GNAT) domain
CFDIMMCL_01063 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
CFDIMMCL_01064 6.6e-55 yajQ S Belongs to the UPF0234 family
CFDIMMCL_01065 1.8e-161 cvfB S protein conserved in bacteria
CFDIMMCL_01066 6.7e-176 yufN S ABC transporter substrate-binding protein PnrA-like
CFDIMMCL_01067 1.8e-237 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
CFDIMMCL_01068 1.3e-245 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
CFDIMMCL_01070 1.3e-159 yitS S protein conserved in bacteria
CFDIMMCL_01071 3.9e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
CFDIMMCL_01072 2.9e-81 ipi S Intracellular proteinase inhibitor
CFDIMMCL_01073 4.4e-26 S Protein of unknown function (DUF3813)
CFDIMMCL_01074 3.5e-07
CFDIMMCL_01075 2.7e-154 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
CFDIMMCL_01076 4.8e-145 yjfP S COG1073 Hydrolases of the alpha beta superfamily
CFDIMMCL_01077 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
CFDIMMCL_01078 2.2e-81 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
CFDIMMCL_01079 7.8e-274 yitY C D-arabinono-1,4-lactone oxidase
CFDIMMCL_01080 4.1e-90 norB G Major Facilitator Superfamily
CFDIMMCL_01081 1e-198 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CFDIMMCL_01082 7.2e-228 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CFDIMMCL_01083 1.5e-138 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
CFDIMMCL_01084 3.1e-220 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
CFDIMMCL_01085 6.3e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
CFDIMMCL_01086 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
CFDIMMCL_01087 1.3e-177 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CFDIMMCL_01088 1.2e-27 yjzC S YjzC-like protein
CFDIMMCL_01089 1.5e-23 yjzD S Protein of unknown function (DUF2929)
CFDIMMCL_01090 6.8e-141 yjaU I carboxylic ester hydrolase activity
CFDIMMCL_01091 1.5e-106 yjaV
CFDIMMCL_01092 1.9e-166 med S Transcriptional activator protein med
CFDIMMCL_01093 1.1e-26 comZ S ComZ
CFDIMMCL_01094 5.9e-32 yjzB
CFDIMMCL_01095 1.1e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CFDIMMCL_01096 8.9e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CFDIMMCL_01097 5.6e-149 yjaZ O Zn-dependent protease
CFDIMMCL_01098 3.3e-183 appD P Belongs to the ABC transporter superfamily
CFDIMMCL_01099 5.9e-188 appF E Belongs to the ABC transporter superfamily
CFDIMMCL_01100 7.5e-219 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
CFDIMMCL_01101 8e-91 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
CFDIMMCL_01102 2.2e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFDIMMCL_01103 1e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFDIMMCL_01104 5.5e-146 yjbA S Belongs to the UPF0736 family
CFDIMMCL_01105 8e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
CFDIMMCL_01106 0.0 oppA E ABC transporter substrate-binding protein
CFDIMMCL_01107 9.2e-167 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFDIMMCL_01108 1.3e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFDIMMCL_01109 2.7e-202 oppD P Belongs to the ABC transporter superfamily
CFDIMMCL_01110 2.5e-172 oppF E Belongs to the ABC transporter superfamily
CFDIMMCL_01111 3.9e-234 S Putative glycosyl hydrolase domain
CFDIMMCL_01112 2e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CFDIMMCL_01113 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
CFDIMMCL_01114 1.9e-110 yjbE P Integral membrane protein TerC family
CFDIMMCL_01115 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
CFDIMMCL_01116 3.5e-224 yjbF S Competence protein
CFDIMMCL_01117 0.0 pepF E oligoendopeptidase F
CFDIMMCL_01118 5.8e-19
CFDIMMCL_01119 7.8e-171 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
CFDIMMCL_01120 4.8e-72 yjbI S Bacterial-like globin
CFDIMMCL_01121 1.2e-118 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
CFDIMMCL_01122 1.1e-101 yjbK S protein conserved in bacteria
CFDIMMCL_01123 1.6e-61 yjbL S Belongs to the UPF0738 family
CFDIMMCL_01124 2.3e-108 yjbM 2.7.6.5 S GTP pyrophosphokinase
CFDIMMCL_01125 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CFDIMMCL_01126 5.7e-166 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CFDIMMCL_01127 4.2e-146 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
CFDIMMCL_01128 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
CFDIMMCL_01129 5.2e-138 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CFDIMMCL_01130 1.9e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
CFDIMMCL_01131 2.3e-220 thiO 1.4.3.19 E Glycine oxidase
CFDIMMCL_01132 1.4e-30 thiS H Thiamine biosynthesis
CFDIMMCL_01133 2.6e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
CFDIMMCL_01134 9.9e-191 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
CFDIMMCL_01135 2e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
CFDIMMCL_01136 1.4e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
CFDIMMCL_01137 3e-89 yjbX S Spore coat protein
CFDIMMCL_01138 1e-83 cotZ S Spore coat protein
CFDIMMCL_01139 9.2e-94 cotY S Spore coat protein Z
CFDIMMCL_01140 1.5e-75 cotX S Spore Coat Protein X and V domain
CFDIMMCL_01141 1.1e-23 cotW
CFDIMMCL_01142 3.2e-57 cotV S Spore Coat Protein X and V domain
CFDIMMCL_01143 8.7e-57 yjcA S Protein of unknown function (DUF1360)
CFDIMMCL_01146 3.8e-38 spoVIF S Stage VI sporulation protein F
CFDIMMCL_01147 0.0 yjcD 3.6.4.12 L DNA helicase
CFDIMMCL_01148 1.2e-36
CFDIMMCL_01149 3.6e-145 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
CFDIMMCL_01150 2.3e-125 S ABC-2 type transporter
CFDIMMCL_01151 1.8e-133 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
CFDIMMCL_01152 9.4e-36 K SpoVT / AbrB like domain
CFDIMMCL_01153 5e-75 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CFDIMMCL_01154 1.1e-92 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
CFDIMMCL_01155 5.5e-127 yjcH P COG2382 Enterochelin esterase and related enzymes
CFDIMMCL_01156 5.4e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
CFDIMMCL_01157 9.1e-220 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
CFDIMMCL_01159 8.7e-31
CFDIMMCL_01160 1.6e-85
CFDIMMCL_01161 1.7e-97 yobL L Belongs to the WXG100 family
CFDIMMCL_01162 5.9e-96 yobL L Belongs to the WXG100 family
CFDIMMCL_01164 5.9e-87
CFDIMMCL_01166 3.9e-13
CFDIMMCL_01168 8.2e-57
CFDIMMCL_01169 3.5e-82 yobL S Bacterial EndoU nuclease
CFDIMMCL_01170 1.4e-96 yobL S Bacterial EndoU nuclease
CFDIMMCL_01171 3.2e-95
CFDIMMCL_01174 2.4e-135
CFDIMMCL_01177 5.7e-169 bla 3.5.2.6 V beta-lactamase
CFDIMMCL_01178 8.4e-47 yjcS S Antibiotic biosynthesis monooxygenase
CFDIMMCL_01179 1.6e-255 yfjF EGP Belongs to the major facilitator superfamily
CFDIMMCL_01180 7.9e-82 napB K helix_turn_helix multiple antibiotic resistance protein
CFDIMMCL_01181 8.3e-223 ganA 3.2.1.89 G arabinogalactan
CFDIMMCL_01182 3.2e-294 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
CFDIMMCL_01183 2.2e-190 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
CFDIMMCL_01184 9e-220 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CFDIMMCL_01185 0.0 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CFDIMMCL_01186 9.1e-50 lacF 2.7.1.207 G phosphotransferase system
CFDIMMCL_01187 7.3e-285 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
CFDIMMCL_01188 5.1e-139 lacR K COG1349 Transcriptional regulators of sugar metabolism
CFDIMMCL_01189 1.1e-127 5.4.2.6 S Haloacid dehalogenase-like hydrolase
CFDIMMCL_01190 1.5e-145 N Kelch motif
CFDIMMCL_01192 8.1e-106 yhiD S MgtC SapB transporter
CFDIMMCL_01194 7.5e-22 yjfB S Putative motility protein
CFDIMMCL_01195 2.6e-70 T PhoQ Sensor
CFDIMMCL_01196 1.7e-102 yjgB S Domain of unknown function (DUF4309)
CFDIMMCL_01197 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
CFDIMMCL_01198 4.3e-92 yjgD S Protein of unknown function (DUF1641)
CFDIMMCL_01199 4.2e-228 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
CFDIMMCL_01200 3.6e-224 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
CFDIMMCL_01201 6.8e-29
CFDIMMCL_01202 5.9e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
CFDIMMCL_01203 9.3e-125 ybbM S transport system, permease component
CFDIMMCL_01204 2.4e-133 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
CFDIMMCL_01205 1.7e-179 yjlA EG Putative multidrug resistance efflux transporter
CFDIMMCL_01206 6.1e-93 yjlB S Cupin domain
CFDIMMCL_01207 7e-66 yjlC S Protein of unknown function (DUF1641)
CFDIMMCL_01208 3.5e-219 yjlD 1.6.99.3 C NADH dehydrogenase
CFDIMMCL_01209 5.4e-280 uxaC 5.3.1.12 G glucuronate isomerase
CFDIMMCL_01210 3e-254 yjmB G symporter YjmB
CFDIMMCL_01211 3.4e-183 exuR K transcriptional
CFDIMMCL_01212 1.5e-285 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
CFDIMMCL_01213 2e-288 uxaA 4.2.1.7, 4.4.1.24 G Altronate
CFDIMMCL_01214 3.9e-131 MA20_18170 S membrane transporter protein
CFDIMMCL_01215 7.3e-80 yjoA S DinB family
CFDIMMCL_01216 4.9e-215 S response regulator aspartate phosphatase
CFDIMMCL_01218 2.2e-168 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
CFDIMMCL_01219 4.7e-61 yjqA S Bacterial PH domain
CFDIMMCL_01220 2.5e-112 yjqB S phage-related replication protein
CFDIMMCL_01221 7.8e-111 xkdA E IrrE N-terminal-like domain
CFDIMMCL_01222 1.1e-56 xre K Helix-turn-helix XRE-family like proteins
CFDIMMCL_01224 1.4e-17 xkdB K sequence-specific DNA binding
CFDIMMCL_01225 2.6e-154 xkdC L Bacterial dnaA protein
CFDIMMCL_01228 2e-10 yqaO S Phage-like element PBSX protein XtrA
CFDIMMCL_01229 2.8e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
CFDIMMCL_01230 2.1e-35 xtmA
CFDIMMCL_01231 1.4e-41
CFDIMMCL_01233 1.7e-30 xkdX
CFDIMMCL_01234 7.6e-143 xepA
CFDIMMCL_01235 8.7e-38 xhlA S Haemolysin XhlA
CFDIMMCL_01236 1.3e-38 xhlB S SPP1 phage holin
CFDIMMCL_01237 6.4e-170 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
CFDIMMCL_01238 8.7e-23 spoIISB S Stage II sporulation protein SB
CFDIMMCL_01239 7.5e-135 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
CFDIMMCL_01240 2e-175 pit P phosphate transporter
CFDIMMCL_01241 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
CFDIMMCL_01242 3.8e-243 steT E amino acid
CFDIMMCL_01243 5e-184 mhqA E COG0346 Lactoylglutathione lyase and related lyases
CFDIMMCL_01244 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CFDIMMCL_01245 3.4e-180 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
CFDIMMCL_01247 2.7e-207 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFDIMMCL_01248 3.2e-289 yubD P Major Facilitator Superfamily
CFDIMMCL_01250 6.5e-156 dppA E D-aminopeptidase
CFDIMMCL_01251 6.4e-160 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFDIMMCL_01252 5e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFDIMMCL_01253 5.4e-192 dppD P Belongs to the ABC transporter superfamily
CFDIMMCL_01254 0.0 dppE E ABC transporter substrate-binding protein
CFDIMMCL_01255 6.8e-178 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
CFDIMMCL_01256 1e-204 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
CFDIMMCL_01257 6.8e-175 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
CFDIMMCL_01258 1.5e-183 ykfD E Belongs to the ABC transporter superfamily
CFDIMMCL_01259 1.3e-206 pgl 3.1.1.31 G 6-phosphogluconolactonase
CFDIMMCL_01260 1.2e-160 ykgA E Amidinotransferase
CFDIMMCL_01261 8.4e-93 ykhA 3.1.2.20 I Acyl-CoA hydrolase
CFDIMMCL_01262 1.6e-102 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
CFDIMMCL_01263 9.4e-53 ykkC P Multidrug resistance protein
CFDIMMCL_01264 3.4e-49 ykkD P Multidrug resistance protein
CFDIMMCL_01265 7.8e-171 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
CFDIMMCL_01266 4.1e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CFDIMMCL_01267 3.6e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CFDIMMCL_01268 1.5e-71 ohrA O Organic hydroperoxide resistance protein
CFDIMMCL_01269 6.1e-88 ohrR K COG1846 Transcriptional regulators
CFDIMMCL_01270 4.2e-71 ohrB O Organic hydroperoxide resistance protein
CFDIMMCL_01271 9.5e-61 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CFDIMMCL_01273 8.1e-218 M Glycosyl transferase family 2
CFDIMMCL_01274 2.2e-135 M PFAM Collagen triple helix repeat (20 copies)
CFDIMMCL_01275 6.5e-218 hcaT 1.5.1.2 EGP Major facilitator Superfamily
CFDIMMCL_01276 4.1e-124 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
CFDIMMCL_01277 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CFDIMMCL_01278 1.2e-177 isp O Belongs to the peptidase S8 family
CFDIMMCL_01279 8.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CFDIMMCL_01280 9.3e-133 ykoC P Cobalt transport protein
CFDIMMCL_01281 0.0 P ABC transporter, ATP-binding protein
CFDIMMCL_01282 2.4e-99 ykoE S ABC-type cobalt transport system, permease component
CFDIMMCL_01283 1.2e-246 ydhD M Glycosyl hydrolase
CFDIMMCL_01285 2.2e-238 mgtE P Acts as a magnesium transporter
CFDIMMCL_01286 5.4e-53 tnrA K transcriptional
CFDIMMCL_01287 1.9e-16
CFDIMMCL_01288 3.1e-26 ykoL
CFDIMMCL_01289 1.1e-80 ykoM K transcriptional
CFDIMMCL_01290 2.2e-99 ykoP G polysaccharide deacetylase
CFDIMMCL_01291 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
CFDIMMCL_01292 1.4e-153 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CFDIMMCL_01293 4.1e-101 ykoX S membrane-associated protein
CFDIMMCL_01294 9.2e-136 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
CFDIMMCL_01295 4.5e-72 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFDIMMCL_01296 7.9e-21 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFDIMMCL_01297 8.1e-120 rsgI S Anti-sigma factor N-terminus
CFDIMMCL_01298 2.5e-26 sspD S small acid-soluble spore protein
CFDIMMCL_01299 2.7e-126 ykrK S Domain of unknown function (DUF1836)
CFDIMMCL_01300 4.1e-156 htpX O Belongs to the peptidase M48B family
CFDIMMCL_01301 4.3e-242 ktrB P COG0168 Trk-type K transport systems, membrane components
CFDIMMCL_01302 4.7e-116 ydfR S Protein of unknown function (DUF421)
CFDIMMCL_01303 8.2e-193 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
CFDIMMCL_01304 4.4e-65 kinE 2.7.13.3 T Histidine kinase
CFDIMMCL_01305 0.0 kinE 2.7.13.3 T Histidine kinase
CFDIMMCL_01306 2.4e-89 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFDIMMCL_01308 4.4e-197 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CFDIMMCL_01309 1.2e-227 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CFDIMMCL_01310 1.2e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
CFDIMMCL_01311 5.8e-230 mtnE 2.6.1.83 E Aminotransferase
CFDIMMCL_01312 2.5e-228 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
CFDIMMCL_01313 4.4e-137 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
CFDIMMCL_01314 2.2e-116 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
CFDIMMCL_01315 1.3e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CFDIMMCL_01316 3.4e-10 S Spo0E like sporulation regulatory protein
CFDIMMCL_01317 4.3e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
CFDIMMCL_01318 1.5e-77 ykvE K transcriptional
CFDIMMCL_01319 2.7e-127 motB N Flagellar motor protein
CFDIMMCL_01320 1.1e-136 motA N flagellar motor
CFDIMMCL_01321 0.0 clpE O Belongs to the ClpA ClpB family
CFDIMMCL_01322 1.4e-184 ykvI S membrane
CFDIMMCL_01323 1.8e-193
CFDIMMCL_01324 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CFDIMMCL_01325 6.3e-81 queD 4.1.2.50, 4.2.3.12 H synthase
CFDIMMCL_01326 2.2e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
CFDIMMCL_01327 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CFDIMMCL_01329 1.5e-58 ykvN K Transcriptional regulator
CFDIMMCL_01330 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
CFDIMMCL_01331 1.4e-32 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CFDIMMCL_01332 7e-46 ykvR S Protein of unknown function (DUF3219)
CFDIMMCL_01333 7.8e-25 ykvS S protein conserved in bacteria
CFDIMMCL_01334 6e-28
CFDIMMCL_01335 6.3e-111 ykvT 3.5.1.28 M Cell Wall Hydrolase
CFDIMMCL_01336 6.2e-241 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CFDIMMCL_01337 1.1e-89 stoA CO thiol-disulfide
CFDIMMCL_01338 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
CFDIMMCL_01339 7.4e-208 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
CFDIMMCL_01341 1.2e-177 ykvZ 5.1.1.1 K Transcriptional regulator
CFDIMMCL_01342 5.1e-156 glcT K antiterminator
CFDIMMCL_01343 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CFDIMMCL_01344 2.1e-39 ptsH G phosphocarrier protein HPr
CFDIMMCL_01345 5e-301 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CFDIMMCL_01346 6.1e-38 splA S Transcriptional regulator
CFDIMMCL_01347 2.9e-190 splB 4.1.99.14 L Spore photoproduct lyase
CFDIMMCL_01348 4.4e-267 mcpC NT chemotaxis protein
CFDIMMCL_01349 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
CFDIMMCL_01350 7.2e-65
CFDIMMCL_01351 1.4e-120 ykwD J protein with SCP PR1 domains
CFDIMMCL_01352 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
CFDIMMCL_01353 2.6e-290 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
CFDIMMCL_01354 1.3e-215 patA 2.6.1.1 E Aminotransferase
CFDIMMCL_01355 2.3e-09
CFDIMMCL_01356 3.7e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
CFDIMMCL_01357 1.4e-83 ykyB S YkyB-like protein
CFDIMMCL_01358 1.6e-241 ykuC EGP Major facilitator Superfamily
CFDIMMCL_01359 3.2e-89 ykuD S protein conserved in bacteria
CFDIMMCL_01360 3.8e-159 ykuE S Metallophosphoesterase
CFDIMMCL_01361 1.3e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CFDIMMCL_01362 1.5e-233 ykuI T Diguanylate phosphodiesterase
CFDIMMCL_01363 3.9e-37 ykuJ S protein conserved in bacteria
CFDIMMCL_01364 7.6e-94 ykuK S Ribonuclease H-like
CFDIMMCL_01365 2.5e-26 ykzF S Antirepressor AbbA
CFDIMMCL_01366 1e-75 ykuL S CBS domain
CFDIMMCL_01367 4.6e-168 ccpC K Transcriptional regulator
CFDIMMCL_01368 6.1e-90 fld C Flavodoxin
CFDIMMCL_01369 4.4e-174 ykuO
CFDIMMCL_01370 1.1e-80 fld C Flavodoxin
CFDIMMCL_01371 8.8e-77 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
CFDIMMCL_01372 5.3e-217 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
CFDIMMCL_01373 4.8e-38 ykuS S Belongs to the UPF0180 family
CFDIMMCL_01374 1.5e-141 ykuT M Mechanosensitive ion channel
CFDIMMCL_01375 7.7e-82 ykuV CO thiol-disulfide
CFDIMMCL_01376 1.5e-98 rok K Repressor of ComK
CFDIMMCL_01377 8.6e-163 yknT
CFDIMMCL_01378 1.6e-12 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
CFDIMMCL_01379 1.5e-89 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
CFDIMMCL_01380 2.9e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
CFDIMMCL_01381 9.6e-247 moeA 2.10.1.1 H molybdopterin
CFDIMMCL_01382 2.6e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
CFDIMMCL_01383 7.1e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
CFDIMMCL_01384 1.5e-33 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CFDIMMCL_01385 6.6e-109 yknW S Yip1 domain
CFDIMMCL_01386 1.4e-172 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFDIMMCL_01387 7.1e-104 macB V ABC transporter, ATP-binding protein
CFDIMMCL_01388 4.9e-213 yknZ V ABC transporter (permease)
CFDIMMCL_01389 1.1e-133 fruR K Transcriptional regulator
CFDIMMCL_01390 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
CFDIMMCL_01391 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
CFDIMMCL_01392 1.5e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
CFDIMMCL_01393 8.9e-38 ykoA
CFDIMMCL_01394 2.2e-309 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
CFDIMMCL_01395 1.1e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CFDIMMCL_01396 4.5e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
CFDIMMCL_01397 7.2e-12 S Uncharacterized protein YkpC
CFDIMMCL_01398 3.7e-131 mreB D Rod-share determining protein MreBH
CFDIMMCL_01399 2.6e-43 mreB D Rod-share determining protein MreBH
CFDIMMCL_01400 2.1e-45 abrB K of stationary sporulation gene expression
CFDIMMCL_01401 3.7e-246 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
CFDIMMCL_01402 2.8e-151 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
CFDIMMCL_01403 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
CFDIMMCL_01404 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CFDIMMCL_01405 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CFDIMMCL_01406 8.2e-31 ykzG S Belongs to the UPF0356 family
CFDIMMCL_01407 1.6e-148 ykrA S hydrolases of the HAD superfamily
CFDIMMCL_01408 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CFDIMMCL_01410 8.1e-106 recN L Putative cell-wall binding lipoprotein
CFDIMMCL_01411 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
CFDIMMCL_01412 0.0 Q Polyketide synthase of type I
CFDIMMCL_01413 0.0 Q Polyketide synthase of type I
CFDIMMCL_01414 0.0 Q Polyketide synthase of type I
CFDIMMCL_01415 0.0 Q polyketide synthase
CFDIMMCL_01416 0.0 Q Polyketide synthase of type I
CFDIMMCL_01417 0.0 Q Polyketide synthase of type I
CFDIMMCL_01418 0.0 Q Polyketide synthase of type I
CFDIMMCL_01419 0.0 Q Polyketide synthase of type I
CFDIMMCL_01420 0.0 Q Polyketide synthase of type I
CFDIMMCL_01421 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
CFDIMMCL_01422 1.2e-213 V Beta-lactamase
CFDIMMCL_01423 2.7e-205 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
CFDIMMCL_01424 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
CFDIMMCL_01425 3.4e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CFDIMMCL_01426 5e-241 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
CFDIMMCL_01427 3e-44 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
CFDIMMCL_01428 4.4e-141 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
CFDIMMCL_01429 3.1e-278 speA 4.1.1.19 E Arginine
CFDIMMCL_01430 1.6e-42 yktA S Belongs to the UPF0223 family
CFDIMMCL_01431 4.9e-119 yktB S Belongs to the UPF0637 family
CFDIMMCL_01432 9.7e-25 ykzI
CFDIMMCL_01433 4.2e-152 suhB 3.1.3.25 G Inositol monophosphatase
CFDIMMCL_01434 1.8e-83 ykzC S Acetyltransferase (GNAT) family
CFDIMMCL_01435 2.7e-296 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
CFDIMMCL_01436 4.3e-200 ylaA
CFDIMMCL_01437 5e-142
CFDIMMCL_01438 8.9e-46 ylaB
CFDIMMCL_01439 2.2e-93 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
CFDIMMCL_01440 9.8e-14 sigC S Putative zinc-finger
CFDIMMCL_01441 4.4e-40 ylaE
CFDIMMCL_01442 6.7e-24 S Family of unknown function (DUF5325)
CFDIMMCL_01443 0.0 typA T GTP-binding protein TypA
CFDIMMCL_01444 1.3e-48 ylaH S YlaH-like protein
CFDIMMCL_01445 1e-33 ylaI S protein conserved in bacteria
CFDIMMCL_01446 2.3e-105 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
CFDIMMCL_01447 5.8e-247 phoH T ATPase related to phosphate starvation-inducible protein PhoH
CFDIMMCL_01448 7.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CFDIMMCL_01449 1.8e-175 glsA 3.5.1.2 E Belongs to the glutaminase family
CFDIMMCL_01450 8.7e-44 ylaN S Belongs to the UPF0358 family
CFDIMMCL_01451 9e-215 ftsW D Belongs to the SEDS family
CFDIMMCL_01452 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CFDIMMCL_01453 2e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
CFDIMMCL_01454 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
CFDIMMCL_01455 1.4e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
CFDIMMCL_01456 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CFDIMMCL_01457 2.4e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
CFDIMMCL_01458 2.7e-52 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
CFDIMMCL_01459 1.1e-166 ctaG S cytochrome c oxidase
CFDIMMCL_01460 5.9e-61 ylbA S YugN-like family
CFDIMMCL_01461 2.2e-73 ylbB T COG0517 FOG CBS domain
CFDIMMCL_01462 2.1e-199 ylbC S protein with SCP PR1 domains
CFDIMMCL_01463 4.5e-57 ylbD S Putative coat protein
CFDIMMCL_01464 8.8e-37 ylbE S YlbE-like protein
CFDIMMCL_01465 1.2e-71 ylbF S Belongs to the UPF0342 family
CFDIMMCL_01466 5.5e-43 ylbG S UPF0298 protein
CFDIMMCL_01468 8.5e-90 rsmD 2.1.1.171 L Methyltransferase
CFDIMMCL_01469 1.1e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CFDIMMCL_01470 2e-217 ylbJ S Sporulation integral membrane protein YlbJ
CFDIMMCL_01471 8.9e-139 ylbK S esterase of the alpha-beta hydrolase superfamily
CFDIMMCL_01472 5.5e-189 ylbL T Belongs to the peptidase S16 family
CFDIMMCL_01473 1.4e-231 ylbM S Belongs to the UPF0348 family
CFDIMMCL_01474 2.7e-91 yceD S metal-binding, possibly nucleic acid-binding protein
CFDIMMCL_01475 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
CFDIMMCL_01476 1.2e-71 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
CFDIMMCL_01477 8.1e-90 ylbP K n-acetyltransferase
CFDIMMCL_01478 3.5e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CFDIMMCL_01479 0.0 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CFDIMMCL_01480 8.9e-78 mraZ K Belongs to the MraZ family
CFDIMMCL_01481 5.1e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
CFDIMMCL_01482 2.9e-52 ftsL D Essential cell division protein
CFDIMMCL_01483 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
CFDIMMCL_01484 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
CFDIMMCL_01485 1.4e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CFDIMMCL_01486 1.7e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CFDIMMCL_01487 1.2e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CFDIMMCL_01488 2.2e-185 spoVE D Belongs to the SEDS family
CFDIMMCL_01489 2.1e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CFDIMMCL_01490 5.6e-169 murB 1.3.1.98 M cell wall formation
CFDIMMCL_01491 1.3e-134 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
CFDIMMCL_01492 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
CFDIMMCL_01493 1.2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CFDIMMCL_01495 6e-34 bpr O COG1404 Subtilisin-like serine proteases
CFDIMMCL_01496 0.0 bpr O COG1404 Subtilisin-like serine proteases
CFDIMMCL_01497 4e-162 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
CFDIMMCL_01498 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFDIMMCL_01499 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFDIMMCL_01500 1.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
CFDIMMCL_01501 2.7e-257 argE 3.5.1.16 E Acetylornithine deacetylase
CFDIMMCL_01502 2.2e-38 ylmC S sporulation protein
CFDIMMCL_01503 1e-161 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
CFDIMMCL_01504 2.5e-124 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CFDIMMCL_01505 1.5e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
CFDIMMCL_01506 5.2e-41 yggT S membrane
CFDIMMCL_01507 5.5e-141 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
CFDIMMCL_01508 8.9e-68 divIVA D Cell division initiation protein
CFDIMMCL_01509 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CFDIMMCL_01510 6.2e-66 dksA T COG1734 DnaK suppressor protein
CFDIMMCL_01511 5.2e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CFDIMMCL_01512 4.6e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CFDIMMCL_01513 1e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CFDIMMCL_01514 3.6e-233 pyrP F Xanthine uracil
CFDIMMCL_01515 1.5e-169 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
CFDIMMCL_01516 4.9e-251 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
CFDIMMCL_01517 7.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
CFDIMMCL_01518 0.0 carB 6.3.5.5 F Belongs to the CarB family
CFDIMMCL_01519 8.2e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
CFDIMMCL_01520 1.9e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
CFDIMMCL_01521 4.2e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
CFDIMMCL_01522 3.8e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CFDIMMCL_01524 3.8e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
CFDIMMCL_01525 1.8e-179 cysP P phosphate transporter
CFDIMMCL_01526 2.7e-224 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
CFDIMMCL_01527 1.1e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
CFDIMMCL_01528 8.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
CFDIMMCL_01529 3.4e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
CFDIMMCL_01530 1.3e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
CFDIMMCL_01531 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
CFDIMMCL_01532 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
CFDIMMCL_01533 2.4e-167 yloB 3.6.3.8 P COG0474 Cation transport ATPase
CFDIMMCL_01534 7.7e-155 yloC S stress-induced protein
CFDIMMCL_01535 1.5e-40 ylzA S Belongs to the UPF0296 family
CFDIMMCL_01536 8.1e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
CFDIMMCL_01537 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
CFDIMMCL_01538 2.3e-226 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CFDIMMCL_01539 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CFDIMMCL_01540 6e-85 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CFDIMMCL_01541 8e-16 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CFDIMMCL_01542 3.7e-151 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CFDIMMCL_01543 4.2e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CFDIMMCL_01544 9e-206 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CFDIMMCL_01545 9.3e-141 stp 3.1.3.16 T phosphatase
CFDIMMCL_01546 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
CFDIMMCL_01547 5.7e-166 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
CFDIMMCL_01548 9.4e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
CFDIMMCL_01549 1.4e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
CFDIMMCL_01550 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
CFDIMMCL_01551 5.5e-59 asp S protein conserved in bacteria
CFDIMMCL_01552 3.4e-305 yloV S kinase related to dihydroxyacetone kinase
CFDIMMCL_01553 1.6e-117 sdaAB 4.3.1.17 E L-serine dehydratase
CFDIMMCL_01554 7.1e-156 sdaAA 4.3.1.17 E L-serine dehydratase
CFDIMMCL_01555 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CFDIMMCL_01556 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
CFDIMMCL_01557 1.2e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
CFDIMMCL_01558 4.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
CFDIMMCL_01559 4.6e-129 IQ reductase
CFDIMMCL_01560 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFDIMMCL_01561 1.5e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
CFDIMMCL_01562 1.6e-99 smc D Required for chromosome condensation and partitioning
CFDIMMCL_01563 0.0 smc D Required for chromosome condensation and partitioning
CFDIMMCL_01564 4.4e-175 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CFDIMMCL_01565 9.1e-144 S Phosphotransferase enzyme family
CFDIMMCL_01566 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CFDIMMCL_01567 5.1e-227 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CFDIMMCL_01568 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
CFDIMMCL_01569 1.7e-35 ylqC S Belongs to the UPF0109 family
CFDIMMCL_01570 1.3e-61 ylqD S YlqD protein
CFDIMMCL_01571 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CFDIMMCL_01572 2.9e-139 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
CFDIMMCL_01573 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
CFDIMMCL_01574 6.4e-159 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CFDIMMCL_01575 5.3e-128 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CFDIMMCL_01576 0.0 ylqG
CFDIMMCL_01577 2.3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
CFDIMMCL_01578 6.8e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
CFDIMMCL_01579 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CFDIMMCL_01580 1.9e-172 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
CFDIMMCL_01581 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CFDIMMCL_01582 9.7e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CFDIMMCL_01583 7.2e-172 xerC L tyrosine recombinase XerC
CFDIMMCL_01584 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CFDIMMCL_01585 1.6e-234 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CFDIMMCL_01586 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CFDIMMCL_01587 3e-55 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
CFDIMMCL_01588 8.1e-76 flgC N Belongs to the flagella basal body rod proteins family
CFDIMMCL_01589 2.5e-31 fliE N Flagellar hook-basal body
CFDIMMCL_01590 1.4e-263 fliF N The M ring may be actively involved in energy transduction
CFDIMMCL_01591 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
CFDIMMCL_01592 1.3e-91 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
CFDIMMCL_01593 5e-243 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
CFDIMMCL_01594 4.5e-71 fliJ N Flagellar biosynthesis chaperone
CFDIMMCL_01595 4.4e-48 ylxF S MgtE intracellular N domain
CFDIMMCL_01596 1.8e-208 fliK N Flagellar hook-length control protein
CFDIMMCL_01597 4.8e-73 flgD N Flagellar basal body rod modification protein
CFDIMMCL_01598 4e-139 flgG N Flagellar basal body rod
CFDIMMCL_01599 2.4e-58 fliL N Controls the rotational direction of flagella during chemotaxis
CFDIMMCL_01600 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
CFDIMMCL_01601 1.9e-190 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CFDIMMCL_01602 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
CFDIMMCL_01603 1.3e-111 fliZ N Flagellar biosynthesis protein, FliO
CFDIMMCL_01604 4.3e-110 fliP N Plays a role in the flagellum-specific transport system
CFDIMMCL_01605 2e-37 fliQ N Role in flagellar biosynthesis
CFDIMMCL_01606 4e-131 fliR N Flagellar biosynthetic protein FliR
CFDIMMCL_01607 2.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CFDIMMCL_01608 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CFDIMMCL_01609 1.9e-195 flhF N Flagellar biosynthesis regulator FlhF
CFDIMMCL_01610 7.5e-158 flhG D Belongs to the ParA family
CFDIMMCL_01611 1.3e-193 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
CFDIMMCL_01612 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
CFDIMMCL_01613 8.8e-81 cheW NT COG0835 Chemotaxis signal transduction protein
CFDIMMCL_01614 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
CFDIMMCL_01615 5.1e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
CFDIMMCL_01616 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFDIMMCL_01617 8.1e-55 ylxL
CFDIMMCL_01618 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
CFDIMMCL_01619 5.3e-156 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CFDIMMCL_01620 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
CFDIMMCL_01621 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
CFDIMMCL_01622 2.2e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CFDIMMCL_01623 6.9e-139 cdsA 2.7.7.41 S Belongs to the CDS family
CFDIMMCL_01624 2e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
CFDIMMCL_01625 3.1e-234 rasP M zinc metalloprotease
CFDIMMCL_01626 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
CFDIMMCL_01627 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CFDIMMCL_01628 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
CFDIMMCL_01629 5.4e-206 nusA K Participates in both transcription termination and antitermination
CFDIMMCL_01630 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
CFDIMMCL_01631 1.8e-47 ylxQ J ribosomal protein
CFDIMMCL_01632 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CFDIMMCL_01633 3.9e-44 ylxP S protein conserved in bacteria
CFDIMMCL_01634 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CFDIMMCL_01635 8.6e-173 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CFDIMMCL_01636 9.3e-183 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
CFDIMMCL_01637 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CFDIMMCL_01638 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
CFDIMMCL_01639 8e-182 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
CFDIMMCL_01640 3.6e-235 pepR S Belongs to the peptidase M16 family
CFDIMMCL_01641 2.6e-42 ymxH S YlmC YmxH family
CFDIMMCL_01642 1.1e-161 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
CFDIMMCL_01643 2e-106 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
CFDIMMCL_01644 2.6e-194 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CFDIMMCL_01645 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
CFDIMMCL_01646 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFDIMMCL_01647 5.2e-309 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CFDIMMCL_01648 4.5e-129 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
CFDIMMCL_01649 6.3e-31 S YlzJ-like protein
CFDIMMCL_01650 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
CFDIMMCL_01651 1.8e-133 ymfC K Transcriptional regulator
CFDIMMCL_01652 1.7e-230 ymfD EGP Major facilitator Superfamily
CFDIMMCL_01653 1.3e-76 K helix_turn_helix multiple antibiotic resistance protein
CFDIMMCL_01654 0.0 ydgH S drug exporters of the RND superfamily
CFDIMMCL_01655 1.2e-238 ymfF S Peptidase M16
CFDIMMCL_01656 2.3e-245 ymfH S zinc protease
CFDIMMCL_01657 1.6e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
CFDIMMCL_01658 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
CFDIMMCL_01659 3.5e-143 ymfK S Protein of unknown function (DUF3388)
CFDIMMCL_01660 4.8e-128 ymfM S protein conserved in bacteria
CFDIMMCL_01661 3.8e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CFDIMMCL_01662 1.7e-232 cinA 3.5.1.42 S Belongs to the CinA family
CFDIMMCL_01663 6.2e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CFDIMMCL_01664 1.3e-194 pbpX V Beta-lactamase
CFDIMMCL_01665 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
CFDIMMCL_01666 4.9e-153 ymdB S protein conserved in bacteria
CFDIMMCL_01667 1.2e-36 spoVS S Stage V sporulation protein S
CFDIMMCL_01668 1.6e-199 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
CFDIMMCL_01669 6.1e-216 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
CFDIMMCL_01670 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CFDIMMCL_01671 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
CFDIMMCL_01672 1.7e-88 cotE S Spore coat protein
CFDIMMCL_01673 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CFDIMMCL_01674 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CFDIMMCL_01676 3.9e-130 pksB 3.1.2.6 S Polyketide biosynthesis
CFDIMMCL_01677 6.8e-164 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
CFDIMMCL_01678 3.9e-184 pksD Q Acyl transferase domain
CFDIMMCL_01679 1.5e-32 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
CFDIMMCL_01680 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
CFDIMMCL_01681 1.3e-35 acpK IQ Phosphopantetheine attachment site
CFDIMMCL_01682 1.3e-245 pksG 2.3.3.10 I synthase
CFDIMMCL_01683 4.8e-145 pksH 4.2.1.18 I enoyl-CoA hydratase
CFDIMMCL_01684 2.9e-139 pksI I Belongs to the enoyl-CoA hydratase isomerase family
CFDIMMCL_01685 0.0 rhiB IQ polyketide synthase
CFDIMMCL_01686 0.0 Q Polyketide synthase of type I
CFDIMMCL_01687 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
CFDIMMCL_01688 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
CFDIMMCL_01689 0.0 dhbF IQ polyketide synthase
CFDIMMCL_01690 0.0 pks13 HQ Beta-ketoacyl synthase
CFDIMMCL_01691 2.8e-232 cypA C Cytochrome P450
CFDIMMCL_01692 7.5e-79 nucB M Deoxyribonuclease NucA/NucB
CFDIMMCL_01693 9.4e-119 yoaK S Membrane
CFDIMMCL_01694 1.4e-62 ymzB
CFDIMMCL_01695 4.7e-257 aprX O Belongs to the peptidase S8 family
CFDIMMCL_01697 1.4e-127 ymaC S Replication protein
CFDIMMCL_01698 5.4e-80 ymaD O redox protein, regulator of disulfide bond formation
CFDIMMCL_01699 1.5e-51 ebrB P Small Multidrug Resistance protein
CFDIMMCL_01700 3.1e-48 ebrA P Small Multidrug Resistance protein
CFDIMMCL_01702 1.4e-47 ymaF S YmaF family
CFDIMMCL_01703 6.7e-173 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CFDIMMCL_01704 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
CFDIMMCL_01705 2.2e-44
CFDIMMCL_01706 1.8e-20 ymzA
CFDIMMCL_01707 1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
CFDIMMCL_01708 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFDIMMCL_01709 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFDIMMCL_01710 2.4e-110 ymaB S MutT family
CFDIMMCL_01711 1.9e-114 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
CFDIMMCL_01712 1.3e-176 spoVK O stage V sporulation protein K
CFDIMMCL_01713 2.2e-232 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CFDIMMCL_01714 5.7e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
CFDIMMCL_01715 4.3e-68 glnR K transcriptional
CFDIMMCL_01716 1.9e-261 glnA 6.3.1.2 E glutamine synthetase
CFDIMMCL_01717 1e-08 L Belongs to the 'phage' integrase family
CFDIMMCL_01718 2.6e-15
CFDIMMCL_01719 2.9e-95
CFDIMMCL_01721 7.4e-216 mrjp G Major royal jelly protein
CFDIMMCL_01722 6.7e-254 xynT G MFS/sugar transport protein
CFDIMMCL_01723 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
CFDIMMCL_01724 8.3e-218 xylR GK ROK family
CFDIMMCL_01725 2.6e-263 xylA 5.3.1.5 G Belongs to the xylose isomerase family
CFDIMMCL_01726 2.1e-293 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
CFDIMMCL_01727 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
CFDIMMCL_01732 5.4e-17
CFDIMMCL_01733 4e-56 dinB S DinB family
CFDIMMCL_01734 3.5e-188 adhP 1.1.1.1 C alcohol dehydrogenase
CFDIMMCL_01736 2.1e-148 yoaP 3.1.3.18 K YoaP-like
CFDIMMCL_01737 1.3e-101 J Acetyltransferase (GNAT) domain
CFDIMMCL_01738 4.3e-69
CFDIMMCL_01740 1.7e-121 ynaE S Domain of unknown function (DUF3885)
CFDIMMCL_01741 5.4e-203 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFDIMMCL_01742 1.2e-117 AA10,CBM73 S Pfam:Chitin_bind_3
CFDIMMCL_01744 2.4e-95 yvgO
CFDIMMCL_01746 0.0 yobO M Pectate lyase superfamily protein
CFDIMMCL_01747 2.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
CFDIMMCL_01748 1.4e-150 yndL S Replication protein
CFDIMMCL_01749 1.6e-07
CFDIMMCL_01750 2.2e-129 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
CFDIMMCL_01751 1.1e-72 yndM S Protein of unknown function (DUF2512)
CFDIMMCL_01752 2.1e-12 yoaW
CFDIMMCL_01753 2.4e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CFDIMMCL_01754 6.2e-51 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
CFDIMMCL_01755 3.5e-112 yneB L resolvase
CFDIMMCL_01756 9.8e-33 ynzC S UPF0291 protein
CFDIMMCL_01757 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CFDIMMCL_01758 1.3e-81 yneE S Sporulation inhibitor of replication protein sirA
CFDIMMCL_01759 2.3e-28 yneF S UPF0154 protein
CFDIMMCL_01760 2.1e-23 ynzD S Spo0E like sporulation regulatory protein
CFDIMMCL_01761 1.3e-125 ccdA O cytochrome c biogenesis protein
CFDIMMCL_01762 4.7e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
CFDIMMCL_01763 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
CFDIMMCL_01764 8.5e-75 yneK S Protein of unknown function (DUF2621)
CFDIMMCL_01765 1e-63 hspX O Spore coat protein
CFDIMMCL_01766 2.3e-19 sspP S Belongs to the SspP family
CFDIMMCL_01767 7.5e-15 sspO S Belongs to the SspO family
CFDIMMCL_01768 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CFDIMMCL_01769 1.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CFDIMMCL_01771 2.7e-33 tlp S Belongs to the Tlp family
CFDIMMCL_01772 1.3e-75 yneP S Thioesterase-like superfamily
CFDIMMCL_01773 4.4e-54 yneQ
CFDIMMCL_01774 1.3e-50 yneR S Belongs to the HesB IscA family
CFDIMMCL_01775 8.5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CFDIMMCL_01776 1.5e-68 yccU S CoA-binding protein
CFDIMMCL_01777 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CFDIMMCL_01778 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CFDIMMCL_01779 1.2e-13
CFDIMMCL_01780 5.1e-41 ynfC
CFDIMMCL_01781 2.2e-252 agcS E Sodium alanine symporter
CFDIMMCL_01782 5e-184 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
CFDIMMCL_01783 7.2e-197 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
CFDIMMCL_01784 3.1e-113 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
CFDIMMCL_01785 9.5e-216 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
CFDIMMCL_01786 9.8e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CFDIMMCL_01787 4.4e-183 kdgR_1 K transcriptional
CFDIMMCL_01788 5.4e-226 exuT G Sugar (and other) transporter
CFDIMMCL_01789 4.3e-160 yndG S DoxX-like family
CFDIMMCL_01790 3.4e-41 yndH S Domain of unknown function (DUF4166)
CFDIMMCL_01791 2.3e-311 yndJ S YndJ-like protein
CFDIMMCL_01793 1.4e-220 S Platelet-activating factor acetylhydrolase, isoform II
CFDIMMCL_01794 1.9e-299 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
CFDIMMCL_01795 5.6e-52 S Domain of unknown function (DUF4870)
CFDIMMCL_01796 6.7e-238 T PhoQ Sensor
CFDIMMCL_01797 5.2e-130 T Transcriptional regulatory protein, C terminal
CFDIMMCL_01798 1.8e-253 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
CFDIMMCL_01799 4.7e-301 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
CFDIMMCL_01800 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFDIMMCL_01801 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFDIMMCL_01802 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFDIMMCL_01803 2.7e-227 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
CFDIMMCL_01804 8.1e-140 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
CFDIMMCL_01805 1.9e-121 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
CFDIMMCL_01806 2.2e-125 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CFDIMMCL_01807 1.3e-257 yxjC EG COG2610 H gluconate symporter and related permeases
CFDIMMCL_01808 7.8e-227 bioI 1.14.14.46 C Cytochrome P450
CFDIMMCL_01809 9.7e-194 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CFDIMMCL_01810 1.4e-130 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CFDIMMCL_01811 1.7e-215 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
CFDIMMCL_01812 1.9e-261 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
CFDIMMCL_01813 5.5e-149 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
CFDIMMCL_01814 1.7e-72 yngA S membrane
CFDIMMCL_01815 1.4e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
CFDIMMCL_01816 3.2e-104 yngC S SNARE associated Golgi protein
CFDIMMCL_01817 2.6e-291 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
CFDIMMCL_01818 8e-140 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
CFDIMMCL_01819 5e-170 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
CFDIMMCL_01820 7.2e-249 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
CFDIMMCL_01821 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
CFDIMMCL_01822 4.4e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
CFDIMMCL_01823 3.2e-310 yngK T Glycosyl hydrolase-like 10
CFDIMMCL_01824 4.1e-65 yngL S Protein of unknown function (DUF1360)
CFDIMMCL_01825 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
CFDIMMCL_01826 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFDIMMCL_01827 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFDIMMCL_01828 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFDIMMCL_01829 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFDIMMCL_01830 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFDIMMCL_01831 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFDIMMCL_01832 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFDIMMCL_01833 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFDIMMCL_01834 1.6e-274 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
CFDIMMCL_01835 1.1e-189 yoxA 5.1.3.3 G Aldose 1-epimerase
CFDIMMCL_01836 2.7e-247 yoeA V MATE efflux family protein
CFDIMMCL_01837 1.8e-98 yoeB S IseA DL-endopeptidase inhibitor
CFDIMMCL_01839 3.5e-97 L Integrase
CFDIMMCL_01840 1.8e-34 yoeD G Helix-turn-helix domain
CFDIMMCL_01841 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
CFDIMMCL_01842 1.1e-201 ybcL EGP Major facilitator Superfamily
CFDIMMCL_01843 1.8e-50 ybzH K Helix-turn-helix domain
CFDIMMCL_01845 2.1e-114 gltR1 K Transcriptional regulator
CFDIMMCL_01846 5.3e-189 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
CFDIMMCL_01847 1e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
CFDIMMCL_01848 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
CFDIMMCL_01849 3.3e-153 gltC K Transcriptional regulator
CFDIMMCL_01850 1e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CFDIMMCL_01851 2e-141 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CFDIMMCL_01852 1e-61 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
CFDIMMCL_01853 1.1e-77 lipB 2.3.1.181 K Acetyltransferase (GNAT) domain
CFDIMMCL_01854 6.3e-45 L Transposase
CFDIMMCL_01855 2e-138 IQ Enoyl-(Acyl carrier protein) reductase
CFDIMMCL_01856 6e-227 K helix_turn_helix, arabinose operon control protein
CFDIMMCL_01857 5.2e-125 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
CFDIMMCL_01858 2.1e-43 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CFDIMMCL_01859 6.4e-142 yoxB
CFDIMMCL_01860 2.2e-203 yoaB EGP Major facilitator Superfamily
CFDIMMCL_01861 1.1e-280 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
CFDIMMCL_01862 3.9e-195 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFDIMMCL_01863 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CFDIMMCL_01864 6.2e-16 yoaF
CFDIMMCL_01866 7.1e-101 hpr K helix_turn_helix multiple antibiotic resistance protein
CFDIMMCL_01867 1.6e-45
CFDIMMCL_01868 2.5e-88 S SMI1-KNR4 cell-wall
CFDIMMCL_01869 0.0 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
CFDIMMCL_01870 4.9e-54 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
CFDIMMCL_01871 7.1e-135 yobQ K helix_turn_helix, arabinose operon control protein
CFDIMMCL_01872 7.5e-95 yobS K Transcriptional regulator
CFDIMMCL_01873 4.5e-137 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
CFDIMMCL_01874 2.9e-66 yobW
CFDIMMCL_01875 3.4e-55 czrA K transcriptional
CFDIMMCL_01876 5.5e-121 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
CFDIMMCL_01877 2.8e-91 yozB S membrane
CFDIMMCL_01878 5.4e-144 yocB J Protein required for attachment to host cells
CFDIMMCL_01879 1.9e-94 yocC
CFDIMMCL_01880 5.3e-189 yocD 3.4.17.13 V peptidase S66
CFDIMMCL_01882 2.5e-118 yocH CBM50 M COG1388 FOG LysM repeat
CFDIMMCL_01883 0.0 recQ 3.6.4.12 L DNA helicase
CFDIMMCL_01884 2.2e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CFDIMMCL_01886 3e-60 dksA T general stress protein
CFDIMMCL_01887 7.8e-10 yocL
CFDIMMCL_01888 1.7e-08
CFDIMMCL_01889 2e-88 yocM O Belongs to the small heat shock protein (HSP20) family
CFDIMMCL_01890 3.8e-44 yozN
CFDIMMCL_01891 8.5e-37 yocN
CFDIMMCL_01892 2.4e-56 yozO S Bacterial PH domain
CFDIMMCL_01894 1.6e-31 yozC
CFDIMMCL_01895 1.5e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
CFDIMMCL_01896 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
CFDIMMCL_01897 3.8e-167 sodA 1.15.1.1 P Superoxide dismutase
CFDIMMCL_01898 3e-235 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
CFDIMMCL_01899 5.8e-164 yocS S -transporter
CFDIMMCL_01900 5.1e-144 S Metallo-beta-lactamase superfamily
CFDIMMCL_01901 5.5e-183 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
CFDIMMCL_01902 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
CFDIMMCL_01903 0.0 yojO P Von Willebrand factor
CFDIMMCL_01904 1.6e-163 yojN S ATPase family associated with various cellular activities (AAA)
CFDIMMCL_01905 2e-111 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CFDIMMCL_01906 2.6e-135 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
CFDIMMCL_01907 3e-226 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
CFDIMMCL_01908 7.4e-112 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CFDIMMCL_01910 5.9e-247 norM V Multidrug efflux pump
CFDIMMCL_01911 4.5e-152 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CFDIMMCL_01912 2.5e-126 yojG S deacetylase
CFDIMMCL_01913 9.7e-61 yojF S Protein of unknown function (DUF1806)
CFDIMMCL_01914 4.9e-23
CFDIMMCL_01915 9.2e-164 rarD S -transporter
CFDIMMCL_01916 1.3e-81 yozR S COG0071 Molecular chaperone (small heat shock protein)
CFDIMMCL_01918 1.6e-67 yodA S tautomerase
CFDIMMCL_01919 1.4e-70 yoaQ S Evidence 4 Homologs of previously reported genes of
CFDIMMCL_01920 1.4e-56 yodB K transcriptional
CFDIMMCL_01921 1.2e-106 yodC C nitroreductase
CFDIMMCL_01922 2.7e-111 mhqD S Carboxylesterase
CFDIMMCL_01923 9.7e-177 yodE E COG0346 Lactoylglutathione lyase and related lyases
CFDIMMCL_01924 1.4e-19 S Protein of unknown function (DUF3311)
CFDIMMCL_01925 3.5e-269 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CFDIMMCL_01926 7.4e-288 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
CFDIMMCL_01927 1.4e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CFDIMMCL_01928 5e-20 yydK K Transcriptional regulator
CFDIMMCL_01929 1.5e-100 yydK K Transcriptional regulator
CFDIMMCL_01930 2.6e-250 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
CFDIMMCL_01931 8.9e-130 yodH Q Methyltransferase
CFDIMMCL_01932 1.1e-34 yodI
CFDIMMCL_01933 1.8e-145 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
CFDIMMCL_01934 9.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
CFDIMMCL_01936 8.6e-56 yodL S YodL-like
CFDIMMCL_01937 5e-105 yodM 3.6.1.27 I Acid phosphatase homologues
CFDIMMCL_01938 6.2e-24 yozD S YozD-like protein
CFDIMMCL_01940 1.7e-125 yodN
CFDIMMCL_01941 4.1e-36 yozE S Belongs to the UPF0346 family
CFDIMMCL_01942 8.3e-47 yokU S YokU-like protein, putative antitoxin
CFDIMMCL_01943 3.2e-280 kamA 5.4.3.2 E lysine 2,3-aminomutase
CFDIMMCL_01944 1.4e-161 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
CFDIMMCL_01945 1.8e-256 yodQ 3.5.1.16 E Acetylornithine deacetylase
CFDIMMCL_01946 1.2e-123 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
CFDIMMCL_01947 5.8e-126 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CFDIMMCL_01948 2.1e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CFDIMMCL_01950 4e-147 yiiD K acetyltransferase
CFDIMMCL_01951 4.4e-252 cgeD M maturation of the outermost layer of the spore
CFDIMMCL_01952 1e-42 cgeC
CFDIMMCL_01953 9.8e-55 cgeA
CFDIMMCL_01954 1.5e-183 cgeB S Spore maturation protein
CFDIMMCL_01955 6.6e-223 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
CFDIMMCL_01956 7.9e-73 4.2.1.115 GM Polysaccharide biosynthesis protein
CFDIMMCL_01960 1.4e-212 S aspartate phosphatase
CFDIMMCL_01961 7.1e-89 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFDIMMCL_01962 1.7e-276 baeB 3.1.2.6, 3.4.21.102 P Rhodanese Homology Domain
CFDIMMCL_01963 8.3e-229 fccB 1.8.5.4 S Pyridine nucleotide-disulphide oxidoreductase
CFDIMMCL_01964 1.5e-98 nreC T helix_turn_helix, Lux Regulon
CFDIMMCL_01965 4.7e-199 2.7.13.3 T Histidine kinase
CFDIMMCL_01966 1.9e-84 yrkJ S response to heat
CFDIMMCL_01968 5.6e-103 yokK S SMI1 / KNR4 family
CFDIMMCL_01969 2.5e-129 S A nuclease of the HNH/ENDO VII superfamily with conserved WHH
CFDIMMCL_01970 0.0 yokA L Recombinase
CFDIMMCL_01971 1.4e-104 4.2.1.115 GM Polysaccharide biosynthesis protein
CFDIMMCL_01972 1.2e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
CFDIMMCL_01973 5.4e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFDIMMCL_01974 4.7e-67 ypoP K transcriptional
CFDIMMCL_01975 5.5e-98 ypmS S protein conserved in bacteria
CFDIMMCL_01976 4e-136 ypmR E GDSL-like Lipase/Acylhydrolase
CFDIMMCL_01977 1e-116 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
CFDIMMCL_01978 2.6e-39 ypmP S Protein of unknown function (DUF2535)
CFDIMMCL_01979 2.2e-243 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CFDIMMCL_01980 4.1e-181 pspF K Transcriptional regulator
CFDIMMCL_01981 9.3e-110 hlyIII S protein, Hemolysin III
CFDIMMCL_01982 5e-116 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
CFDIMMCL_01983 1.3e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CFDIMMCL_01984 8.7e-158 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CFDIMMCL_01985 2.7e-114 ypjP S YpjP-like protein
CFDIMMCL_01986 2.7e-132 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
CFDIMMCL_01987 1e-75 yphP S Belongs to the UPF0403 family
CFDIMMCL_01988 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
CFDIMMCL_01989 6.6e-159 ypgR C COG0694 Thioredoxin-like proteins and domains
CFDIMMCL_01990 1.5e-101 ypgQ S phosphohydrolase
CFDIMMCL_01991 1.1e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
CFDIMMCL_01992 1.1e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CFDIMMCL_01993 1.7e-215 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
CFDIMMCL_01994 1e-30 cspD K Cold-shock protein
CFDIMMCL_01996 7.2e-37 S Protein of unknown function (DUF2564)
CFDIMMCL_01997 1.5e-28 ypeQ S Zinc-finger
CFDIMMCL_01998 6.3e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
CFDIMMCL_01999 3.1e-119 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CFDIMMCL_02000 4.9e-69 rnhA 3.1.26.4 L Ribonuclease
CFDIMMCL_02002 4.8e-165 polA 2.7.7.7 L 5'3' exonuclease
CFDIMMCL_02004 3.5e-39 ypbS S Protein of unknown function (DUF2533)
CFDIMMCL_02005 0.0 ypbR S Dynamin family
CFDIMMCL_02006 1.1e-89 ypbQ S protein conserved in bacteria
CFDIMMCL_02007 2.8e-207 bcsA Q Naringenin-chalcone synthase
CFDIMMCL_02008 1e-110 J Acetyltransferase (GNAT) domain
CFDIMMCL_02009 6.2e-51 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
CFDIMMCL_02010 1.5e-08 S Bacillus cereus group antimicrobial protein
CFDIMMCL_02011 5.2e-99 ydfR S Protein of unknown function (DUF421)
CFDIMMCL_02012 4.1e-101 yrdC 3.5.1.19 Q Isochorismatase family
CFDIMMCL_02014 1.3e-235 pbuX F xanthine
CFDIMMCL_02015 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
CFDIMMCL_02016 3.8e-295 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CFDIMMCL_02017 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
CFDIMMCL_02019 6.6e-22 S YpzG-like protein
CFDIMMCL_02020 3.8e-78 yqgA
CFDIMMCL_02021 4.2e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
CFDIMMCL_02022 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
CFDIMMCL_02023 1.7e-99 ypsA S Belongs to the UPF0398 family
CFDIMMCL_02024 9.9e-33 cotD S Inner spore coat protein D
CFDIMMCL_02026 7.8e-238 yprB L RNase_H superfamily
CFDIMMCL_02027 4.2e-222 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
CFDIMMCL_02028 1.2e-160 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
CFDIMMCL_02029 2.7e-88 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
CFDIMMCL_02030 7.7e-73 hspX O Belongs to the small heat shock protein (HSP20) family
CFDIMMCL_02031 1e-51 yppG S YppG-like protein
CFDIMMCL_02033 4.4e-11 yppE S Bacterial domain of unknown function (DUF1798)
CFDIMMCL_02036 4.5e-147 yppC S Protein of unknown function (DUF2515)
CFDIMMCL_02037 2.7e-111 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
CFDIMMCL_02038 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CFDIMMCL_02039 6.7e-92 ypoC
CFDIMMCL_02040 4.9e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CFDIMMCL_02041 3e-130 dnaD L DNA replication protein DnaD
CFDIMMCL_02042 2e-252 asnS 6.1.1.22 J asparaginyl-tRNA
CFDIMMCL_02043 5.2e-223 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
CFDIMMCL_02044 3.6e-82 ypmB S protein conserved in bacteria
CFDIMMCL_02045 6.7e-23 ypmA S Protein of unknown function (DUF4264)
CFDIMMCL_02046 7.7e-146 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
CFDIMMCL_02047 3.2e-108 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
CFDIMMCL_02048 6.1e-238 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
CFDIMMCL_02049 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CFDIMMCL_02050 5e-159 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CFDIMMCL_02051 2.2e-151 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
CFDIMMCL_02052 4.3e-183 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
CFDIMMCL_02053 1.4e-220 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CFDIMMCL_02054 4.3e-211 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
CFDIMMCL_02055 6.7e-133 bshB1 S proteins, LmbE homologs
CFDIMMCL_02056 1.4e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
CFDIMMCL_02057 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
CFDIMMCL_02058 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
CFDIMMCL_02059 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
CFDIMMCL_02060 3.3e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
CFDIMMCL_02061 5.1e-142 ypjB S sporulation protein
CFDIMMCL_02062 2.6e-106 ypjA S membrane
CFDIMMCL_02063 1e-116 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
CFDIMMCL_02064 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
CFDIMMCL_02065 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
CFDIMMCL_02066 2.9e-78 ypiF S Protein of unknown function (DUF2487)
CFDIMMCL_02067 2.1e-99 ypiB S Belongs to the UPF0302 family
CFDIMMCL_02068 1.4e-234 S COG0457 FOG TPR repeat
CFDIMMCL_02069 6.2e-238 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
CFDIMMCL_02070 1.8e-206 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
CFDIMMCL_02071 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CFDIMMCL_02072 6.5e-145 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
CFDIMMCL_02073 6.8e-231 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CFDIMMCL_02074 2.4e-121 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
CFDIMMCL_02075 2e-132 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
CFDIMMCL_02076 2.8e-161 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CFDIMMCL_02077 2.3e-295 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CFDIMMCL_02078 2.4e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
CFDIMMCL_02079 1e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CFDIMMCL_02080 9.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CFDIMMCL_02081 4.5e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
CFDIMMCL_02082 5.4e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
CFDIMMCL_02083 7.4e-197 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
CFDIMMCL_02084 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
CFDIMMCL_02085 1.1e-30 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
CFDIMMCL_02086 6.2e-94 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
CFDIMMCL_02087 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
CFDIMMCL_02088 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
CFDIMMCL_02089 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CFDIMMCL_02090 2.2e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CFDIMMCL_02091 2e-81 yphF
CFDIMMCL_02092 3.3e-16 yphE S Protein of unknown function (DUF2768)
CFDIMMCL_02093 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
CFDIMMCL_02094 1.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
CFDIMMCL_02095 1.1e-104 yphA
CFDIMMCL_02096 4.7e-08 S YpzI-like protein
CFDIMMCL_02097 8.2e-188 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
CFDIMMCL_02098 1.5e-206 rpsA 1.17.7.4 J Ribosomal protein S1
CFDIMMCL_02099 3.3e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
CFDIMMCL_02100 1.4e-12 S Family of unknown function (DUF5359)
CFDIMMCL_02101 4.8e-19 ypfA M Flagellar protein YcgR
CFDIMMCL_02102 2.2e-26 ypfA M Flagellar protein YcgR
CFDIMMCL_02103 4.2e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
CFDIMMCL_02104 4.9e-162 sleB 3.5.1.28 M Spore cortex-lytic enzyme
CFDIMMCL_02105 8.3e-122 prsW S Involved in the degradation of specific anti-sigma factors
CFDIMMCL_02106 9e-189 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
CFDIMMCL_02107 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
CFDIMMCL_02108 3e-107 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
CFDIMMCL_02109 7.3e-149 ypbG S Calcineurin-like phosphoesterase superfamily domain
CFDIMMCL_02110 2e-85 ypbF S Protein of unknown function (DUF2663)
CFDIMMCL_02111 9.4e-85 ypbE M Lysin motif
CFDIMMCL_02112 9.9e-100 ypbD S metal-dependent membrane protease
CFDIMMCL_02113 1.3e-273 recQ 3.6.4.12 L DNA helicase
CFDIMMCL_02114 2.5e-200 ypbB 5.1.3.1 S protein conserved in bacteria
CFDIMMCL_02115 3.6e-41 fer C Ferredoxin
CFDIMMCL_02116 1.1e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CFDIMMCL_02117 7.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFDIMMCL_02118 8.8e-201 rsiX
CFDIMMCL_02119 6e-85 sigX K Belongs to the sigma-70 factor family. ECF subfamily
CFDIMMCL_02120 0.0 resE 2.7.13.3 T Histidine kinase
CFDIMMCL_02121 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CFDIMMCL_02122 3.2e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
CFDIMMCL_02123 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
CFDIMMCL_02124 1.4e-98 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
CFDIMMCL_02125 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CFDIMMCL_02126 1.3e-88 spmB S Spore maturation protein
CFDIMMCL_02127 2e-103 spmA S Spore maturation protein
CFDIMMCL_02128 2.3e-215 dacB 3.4.16.4 M Belongs to the peptidase S11 family
CFDIMMCL_02129 1.3e-93 ypuI S Protein of unknown function (DUF3907)
CFDIMMCL_02130 7.8e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CFDIMMCL_02131 2.1e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CFDIMMCL_02133 1.7e-93 ypuF S Domain of unknown function (DUF309)
CFDIMMCL_02134 3.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CFDIMMCL_02135 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
CFDIMMCL_02136 3.7e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CFDIMMCL_02137 2e-112 ribE 2.5.1.9 H Riboflavin synthase
CFDIMMCL_02138 8.6e-212 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFDIMMCL_02139 1.7e-49 ypuD
CFDIMMCL_02140 6.9e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
CFDIMMCL_02141 1.3e-82 ccdC1 O Protein of unknown function (DUF1453)
CFDIMMCL_02142 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CFDIMMCL_02143 2.9e-157 ypuA S Secreted protein
CFDIMMCL_02144 1e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
CFDIMMCL_02145 1.4e-270 spoVAF EG Stage V sporulation protein AF
CFDIMMCL_02146 1.8e-110 spoVAEA S stage V sporulation protein
CFDIMMCL_02147 3.8e-57 spoVAEB S stage V sporulation protein
CFDIMMCL_02148 2.9e-190 spoVAD I Stage V sporulation protein AD
CFDIMMCL_02149 2.1e-79 spoVAC S stage V sporulation protein AC
CFDIMMCL_02150 3e-60 spoVAB S Stage V sporulation protein AB
CFDIMMCL_02151 3.7e-111 spoVAA S Stage V sporulation protein AA
CFDIMMCL_02152 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFDIMMCL_02153 1e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
CFDIMMCL_02154 7.8e-58 spoIIAA T Belongs to the anti-sigma-factor antagonist family
CFDIMMCL_02155 4.3e-214 dacF 3.4.16.4 M Belongs to the peptidase S11 family
CFDIMMCL_02156 4.5e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CFDIMMCL_02157 4.7e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
CFDIMMCL_02158 1.7e-165 xerD L recombinase XerD
CFDIMMCL_02159 3.7e-37 S Protein of unknown function (DUF4227)
CFDIMMCL_02160 1.9e-80 fur P Belongs to the Fur family
CFDIMMCL_02161 5.5e-110 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
CFDIMMCL_02163 1.7e-34 yqkK
CFDIMMCL_02164 5.7e-22
CFDIMMCL_02165 7.7e-244 mleA 1.1.1.38 C malic enzyme
CFDIMMCL_02166 5.7e-245 mleN C Na H antiporter
CFDIMMCL_02167 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
CFDIMMCL_02168 6.5e-75 ansA 3.5.1.1 EJ L-asparaginase
CFDIMMCL_02169 2.2e-63 ansA 3.5.1.1 EJ L-asparaginase
CFDIMMCL_02170 7e-59 ansR K Transcriptional regulator
CFDIMMCL_02171 1.6e-224 yqxK 3.6.4.12 L DNA helicase
CFDIMMCL_02172 1.6e-94 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
CFDIMMCL_02174 3.3e-169 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
CFDIMMCL_02176 3.9e-178 yqkD S COG1073 Hydrolases of the alpha beta superfamily
CFDIMMCL_02177 3.2e-39 yqkC S Protein of unknown function (DUF2552)
CFDIMMCL_02178 2e-61 yqkB S Belongs to the HesB IscA family
CFDIMMCL_02179 2.5e-180 yqkA K GrpB protein
CFDIMMCL_02180 4.3e-61 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
CFDIMMCL_02181 3.9e-89 yqjY K acetyltransferase
CFDIMMCL_02182 1.3e-237 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFDIMMCL_02183 5.3e-59 S YolD-like protein
CFDIMMCL_02185 2.8e-191 yueF S transporter activity
CFDIMMCL_02187 6.6e-74 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CFDIMMCL_02188 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
CFDIMMCL_02189 2.1e-260 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
CFDIMMCL_02190 4.1e-144 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
CFDIMMCL_02191 1.6e-131 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
CFDIMMCL_02192 2.6e-36 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
CFDIMMCL_02193 2.1e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CFDIMMCL_02194 1.8e-136 pksI I Belongs to the enoyl-CoA hydratase isomerase family
CFDIMMCL_02195 4.4e-241 pksG 2.3.3.10 I synthase
CFDIMMCL_02196 1.2e-221 eryK 1.14.13.154 C Cytochrome P450
CFDIMMCL_02197 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
CFDIMMCL_02198 0.0 Q Polyketide synthase of type I
CFDIMMCL_02199 0.0 pfaA Q Polyketide synthase of type I
CFDIMMCL_02200 0.0 pksJ Q Polyketide synthase of type I
CFDIMMCL_02201 0.0 Q Polyketide synthase of type I
CFDIMMCL_02202 0.0 1.1.1.320 Q Polyketide synthase of type I
CFDIMMCL_02203 0.0 pksJ Q Polyketide synthase of type I
CFDIMMCL_02204 1.9e-130 IQ reductase
CFDIMMCL_02205 2.1e-213 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
CFDIMMCL_02206 2.9e-25 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
CFDIMMCL_02209 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
CFDIMMCL_02210 1.6e-94 nusG K Participates in transcription elongation, termination and antitermination
CFDIMMCL_02211 2.4e-164 K LysR substrate binding domain
CFDIMMCL_02212 3.8e-51 S GlpM protein
CFDIMMCL_02213 1.6e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
CFDIMMCL_02214 1e-147 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
CFDIMMCL_02215 6.5e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
CFDIMMCL_02216 2.5e-291 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CFDIMMCL_02217 3.4e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CFDIMMCL_02218 3.9e-237 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFDIMMCL_02219 2.4e-25 yqzJ
CFDIMMCL_02220 1.2e-149 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CFDIMMCL_02221 4.7e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
CFDIMMCL_02222 3.6e-293 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
CFDIMMCL_02223 1.3e-75 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
CFDIMMCL_02225 1.7e-96 yqjB S protein conserved in bacteria
CFDIMMCL_02226 6.3e-171 yqjA S Putative aromatic acid exporter C-terminal domain
CFDIMMCL_02227 2.7e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
CFDIMMCL_02228 3.8e-106 artQ E COG0765 ABC-type amino acid transport system, permease component
CFDIMMCL_02229 3.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
CFDIMMCL_02230 1e-75 yqiW S Belongs to the UPF0403 family
CFDIMMCL_02231 4.1e-172 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
CFDIMMCL_02232 1.3e-208 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CFDIMMCL_02233 4.6e-185 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
CFDIMMCL_02234 2.3e-168 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
CFDIMMCL_02235 6.3e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
CFDIMMCL_02236 2e-208 buk 2.7.2.7 C Belongs to the acetokinase family
CFDIMMCL_02237 2.4e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
CFDIMMCL_02238 1.1e-153 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
CFDIMMCL_02239 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
CFDIMMCL_02240 3.2e-34 yqzF S Protein of unknown function (DUF2627)
CFDIMMCL_02241 3.3e-161 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CFDIMMCL_02242 5.5e-280 prpD 4.2.1.79 S 2-methylcitrate dehydratase
CFDIMMCL_02243 1.1e-208 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
CFDIMMCL_02244 3.4e-208 mmgC I acyl-CoA dehydrogenase
CFDIMMCL_02245 3e-156 hbdA 1.1.1.157 I Dehydrogenase
CFDIMMCL_02246 3.4e-214 mmgA 2.3.1.9 I Belongs to the thiolase family
CFDIMMCL_02247 5.1e-136 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
CFDIMMCL_02248 3.6e-106 amiC 3.5.1.28 M Cell wall hydrolase autolysin
CFDIMMCL_02249 3.2e-17
CFDIMMCL_02250 1.5e-101 ytaF P Probably functions as a manganese efflux pump
CFDIMMCL_02251 1.8e-113 K Protein of unknown function (DUF1232)
CFDIMMCL_02253 1.4e-214 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
CFDIMMCL_02256 2.7e-216 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CFDIMMCL_02257 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
CFDIMMCL_02258 2.3e-240 rseP 3.4.21.116 M Stage IV sporulation protein B
CFDIMMCL_02259 8e-180 recN L May be involved in recombinational repair of damaged DNA
CFDIMMCL_02260 4.8e-126 recN L May be involved in recombinational repair of damaged DNA
CFDIMMCL_02261 3.9e-78 argR K Regulates arginine biosynthesis genes
CFDIMMCL_02262 8.7e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
CFDIMMCL_02263 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CFDIMMCL_02264 9.4e-161 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
CFDIMMCL_02265 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CFDIMMCL_02266 3.2e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CFDIMMCL_02267 1.1e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CFDIMMCL_02268 1.1e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CFDIMMCL_02269 6.2e-67 yqhY S protein conserved in bacteria
CFDIMMCL_02270 1.2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
CFDIMMCL_02271 4.9e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
CFDIMMCL_02272 2.5e-62 spoIIIAH S SpoIIIAH-like protein
CFDIMMCL_02273 3.4e-118 spoIIIAG S stage III sporulation protein AG
CFDIMMCL_02274 6.9e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
CFDIMMCL_02275 6.3e-200 spoIIIAE S stage III sporulation protein AE
CFDIMMCL_02276 2.5e-41 spoIIIAD S Stage III sporulation protein AD
CFDIMMCL_02277 7.6e-29 spoIIIAC S stage III sporulation protein AC
CFDIMMCL_02278 5.8e-86 spoIIIAB S Stage III sporulation protein
CFDIMMCL_02279 1.1e-172 spoIIIAA S stage III sporulation protein AA
CFDIMMCL_02280 1.8e-36 yqhV S Protein of unknown function (DUF2619)
CFDIMMCL_02281 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CFDIMMCL_02282 5e-177 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
CFDIMMCL_02283 3.7e-88 yqhR S Conserved membrane protein YqhR
CFDIMMCL_02284 8e-174 yqhQ S Protein of unknown function (DUF1385)
CFDIMMCL_02285 3.4e-62 yqhP
CFDIMMCL_02286 1.1e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
CFDIMMCL_02287 2.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
CFDIMMCL_02288 1e-136 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
CFDIMMCL_02289 7.1e-13 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
CFDIMMCL_02290 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
CFDIMMCL_02291 1.5e-288 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CFDIMMCL_02292 3.8e-254 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CFDIMMCL_02293 3.6e-210 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
CFDIMMCL_02294 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
CFDIMMCL_02295 2.6e-154 yqhG S Bacterial protein YqhG of unknown function
CFDIMMCL_02296 5.2e-23 sinI S Anti-repressor SinI
CFDIMMCL_02297 7.8e-55 sinR K transcriptional
CFDIMMCL_02298 3.3e-141 tasA S Cell division protein FtsN
CFDIMMCL_02299 3.5e-71 sipW 3.4.21.89 U Signal peptidase
CFDIMMCL_02300 3.5e-123 yqxM
CFDIMMCL_02301 1.3e-54 yqzG S Protein of unknown function (DUF3889)
CFDIMMCL_02302 2.3e-26 yqzE S YqzE-like protein
CFDIMMCL_02303 7.8e-64 S ComG operon protein 7
CFDIMMCL_02304 1.5e-68 comGF U Putative Competence protein ComGF
CFDIMMCL_02305 5.8e-20 comGE
CFDIMMCL_02306 1.6e-73 gspH NU Tfp pilus assembly protein FimT
CFDIMMCL_02307 8.9e-50 comGC U Required for transformation and DNA binding
CFDIMMCL_02308 1.8e-187 comGB NU COG1459 Type II secretory pathway, component PulF
CFDIMMCL_02309 7.8e-202 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CFDIMMCL_02310 4.1e-186 corA P Mg2 transporter protein
CFDIMMCL_02311 3.3e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
CFDIMMCL_02312 2.4e-150 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CFDIMMCL_02314 9.2e-65 yqgZ 1.20.4.1 P Belongs to the ArsC family
CFDIMMCL_02315 3.1e-37 yqgY S Protein of unknown function (DUF2626)
CFDIMMCL_02316 1.5e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
CFDIMMCL_02317 5.4e-20 yqgW S Protein of unknown function (DUF2759)
CFDIMMCL_02318 6.9e-50 yqgV S Thiamine-binding protein
CFDIMMCL_02319 7.1e-77 yqgU
CFDIMMCL_02320 1.6e-114 yqgU
CFDIMMCL_02321 2.6e-224 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
CFDIMMCL_02322 2.6e-180 glcK 2.7.1.2 G Glucokinase
CFDIMMCL_02323 1e-28 yqgQ S Protein conserved in bacteria
CFDIMMCL_02324 2.9e-233 nhaC C Na H antiporter
CFDIMMCL_02325 4e-07 yqgO
CFDIMMCL_02326 3.4e-100 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CFDIMMCL_02327 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
CFDIMMCL_02328 1.2e-50 yqzD
CFDIMMCL_02329 3.7e-76 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CFDIMMCL_02330 2.2e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CFDIMMCL_02331 1.8e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CFDIMMCL_02332 6.3e-157 pstA P Phosphate transport system permease
CFDIMMCL_02333 1.4e-159 pstC P probably responsible for the translocation of the substrate across the membrane
CFDIMMCL_02334 7.6e-158 pstS P Phosphate
CFDIMMCL_02335 2.2e-54 L COG2963 Transposase and inactivated derivatives
CFDIMMCL_02336 1.2e-117 L Molecular Function DNA binding, Biological Process DNA recombination
CFDIMMCL_02337 0.0 pbpA 3.4.16.4 M penicillin-binding protein
CFDIMMCL_02338 2e-228 yqgE EGP Major facilitator superfamily
CFDIMMCL_02339 4.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
CFDIMMCL_02340 6e-77 yqgC S protein conserved in bacteria
CFDIMMCL_02341 8.7e-131 yqgB S Protein of unknown function (DUF1189)
CFDIMMCL_02342 3.7e-48 yqfZ M LysM domain
CFDIMMCL_02343 3.1e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CFDIMMCL_02344 2.3e-52 yqfX S membrane
CFDIMMCL_02345 6.5e-110 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
CFDIMMCL_02346 2.9e-72 zur P Belongs to the Fur family
CFDIMMCL_02347 1.4e-156 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
CFDIMMCL_02348 9.3e-37 yqfT S Protein of unknown function (DUF2624)
CFDIMMCL_02349 2e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CFDIMMCL_02350 6.7e-248 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
CFDIMMCL_02351 6.2e-51 yqfQ S YqfQ-like protein
CFDIMMCL_02352 1.7e-176 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CFDIMMCL_02353 1.7e-212 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CFDIMMCL_02354 5.8e-127 trmK 2.1.1.217 S SAM-dependent methyltransferase
CFDIMMCL_02355 1.1e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
CFDIMMCL_02356 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CFDIMMCL_02357 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CFDIMMCL_02358 2.1e-88 yaiI S Belongs to the UPF0178 family
CFDIMMCL_02359 2e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
CFDIMMCL_02360 4.5e-112 ccpN K CBS domain
CFDIMMCL_02361 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
CFDIMMCL_02362 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
CFDIMMCL_02363 4.1e-144 recO L Involved in DNA repair and RecF pathway recombination
CFDIMMCL_02364 1.8e-16 S YqzL-like protein
CFDIMMCL_02365 4e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CFDIMMCL_02366 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
CFDIMMCL_02367 4.6e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
CFDIMMCL_02368 2.5e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CFDIMMCL_02369 0.0 yqfF S membrane-associated HD superfamily hydrolase
CFDIMMCL_02370 3.8e-176 phoH T Phosphate starvation-inducible protein PhoH
CFDIMMCL_02371 1.9e-217 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
CFDIMMCL_02372 9.3e-46 yqfC S sporulation protein YqfC
CFDIMMCL_02373 2.8e-57 yqfB
CFDIMMCL_02374 1.6e-121 yqfA S UPF0365 protein
CFDIMMCL_02375 2e-231 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
CFDIMMCL_02376 1.2e-68 yqeY S Yqey-like protein
CFDIMMCL_02377 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
CFDIMMCL_02378 9.3e-159 yqeW P COG1283 Na phosphate symporter
CFDIMMCL_02379 1.2e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
CFDIMMCL_02380 7.9e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
CFDIMMCL_02381 1.6e-174 prmA J Methylates ribosomal protein L11
CFDIMMCL_02382 1.1e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
CFDIMMCL_02383 0.0 dnaK O Heat shock 70 kDa protein
CFDIMMCL_02384 3.5e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CFDIMMCL_02385 2.3e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
CFDIMMCL_02386 2.8e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
CFDIMMCL_02387 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
CFDIMMCL_02388 3.8e-54 yqxA S Protein of unknown function (DUF3679)
CFDIMMCL_02389 1.4e-220 spoIIP M stage II sporulation protein P
CFDIMMCL_02390 5.9e-205 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CFDIMMCL_02391 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
CFDIMMCL_02392 1.7e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
CFDIMMCL_02393 0.0 comEC S Competence protein ComEC
CFDIMMCL_02394 8e-105 comEB 3.5.4.12 F ComE operon protein 2
CFDIMMCL_02395 7.8e-106 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
CFDIMMCL_02396 2.2e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CFDIMMCL_02397 5.8e-140 yqeM Q Methyltransferase
CFDIMMCL_02398 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
CFDIMMCL_02399 2.5e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
CFDIMMCL_02400 5.9e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CFDIMMCL_02401 1.6e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
CFDIMMCL_02402 4.9e-159 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CFDIMMCL_02403 2.4e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
CFDIMMCL_02404 2e-94 yqeG S hydrolase of the HAD superfamily
CFDIMMCL_02406 9.1e-141 yqeF E GDSL-like Lipase/Acylhydrolase
CFDIMMCL_02407 2.1e-142 3.5.1.104 G Polysaccharide deacetylase
CFDIMMCL_02408 4.2e-107 yqeD S SNARE associated Golgi protein
CFDIMMCL_02409 3.9e-16 2.3.1.57 K Acetyltransferase (GNAT) domain
CFDIMMCL_02410 3.6e-222 EGP Major facilitator Superfamily
CFDIMMCL_02411 4e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFDIMMCL_02412 1.9e-163 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
CFDIMMCL_02413 3.8e-93 K Transcriptional regulator PadR-like family
CFDIMMCL_02414 3e-69 psiE S Belongs to the PsiE family
CFDIMMCL_02415 4.3e-239 yrkQ T Histidine kinase
CFDIMMCL_02416 1.1e-127 T Transcriptional regulator
CFDIMMCL_02418 1.1e-223 yrkO P Protein of unknown function (DUF418)
CFDIMMCL_02419 3.8e-104 yrkN K Acetyltransferase (GNAT) family
CFDIMMCL_02420 2.9e-101 adk 2.7.4.3 F adenylate kinase activity
CFDIMMCL_02421 4.9e-87 yyaR K acetyltransferase
CFDIMMCL_02422 4.7e-93 yrdA S DinB family
CFDIMMCL_02424 4.4e-149 S hydrolase
CFDIMMCL_02425 5.2e-150 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
CFDIMMCL_02426 2.4e-130 glvR K Helix-turn-helix domain, rpiR family
CFDIMMCL_02427 8.4e-192 manA 5.3.1.8 G mannose-6-phosphate isomerase
CFDIMMCL_02428 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
CFDIMMCL_02429 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
CFDIMMCL_02430 2.1e-184 romA S Beta-lactamase superfamily domain
CFDIMMCL_02431 1.2e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CFDIMMCL_02432 9.7e-166 yybE K Transcriptional regulator
CFDIMMCL_02433 5.9e-211 ynfM EGP Major facilitator Superfamily
CFDIMMCL_02434 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
CFDIMMCL_02435 9.1e-101 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
CFDIMMCL_02436 1.2e-94 yrhH Q methyltransferase
CFDIMMCL_02438 8e-143 focA P Formate nitrite
CFDIMMCL_02439 6e-61 yrhF S Uncharacterized conserved protein (DUF2294)
CFDIMMCL_02440 5.3e-150 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
CFDIMMCL_02441 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
CFDIMMCL_02442 7e-81 yrhD S Protein of unknown function (DUF1641)
CFDIMMCL_02443 4.6e-35 yrhC S YrhC-like protein
CFDIMMCL_02444 1.4e-212 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
CFDIMMCL_02445 2.7e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
CFDIMMCL_02446 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CFDIMMCL_02447 2.2e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
CFDIMMCL_02448 4.1e-27 yrzA S Protein of unknown function (DUF2536)
CFDIMMCL_02449 9.5e-71 yrrS S Protein of unknown function (DUF1510)
CFDIMMCL_02450 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
CFDIMMCL_02451 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CFDIMMCL_02452 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
CFDIMMCL_02453 1.6e-246 yegQ O COG0826 Collagenase and related proteases
CFDIMMCL_02454 2e-174 yegQ O Peptidase U32
CFDIMMCL_02455 2.5e-118 yrrM 2.1.1.104 S O-methyltransferase
CFDIMMCL_02456 5.7e-192 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CFDIMMCL_02457 7.1e-46 yrzB S Belongs to the UPF0473 family
CFDIMMCL_02458 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CFDIMMCL_02459 1.7e-41 yrzL S Belongs to the UPF0297 family
CFDIMMCL_02460 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CFDIMMCL_02461 5.2e-166 yrrI S AI-2E family transporter
CFDIMMCL_02462 7.5e-132 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
CFDIMMCL_02463 1.5e-147 glnH ET Belongs to the bacterial solute-binding protein 3 family
CFDIMMCL_02464 4.2e-110 gluC P ABC transporter
CFDIMMCL_02465 3.1e-108 glnP P ABC transporter
CFDIMMCL_02466 2.1e-08 S Protein of unknown function (DUF3918)
CFDIMMCL_02467 2.9e-30 yrzR
CFDIMMCL_02468 1.8e-83 yrrD S protein conserved in bacteria
CFDIMMCL_02469 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
CFDIMMCL_02470 1.7e-18 S COG0457 FOG TPR repeat
CFDIMMCL_02471 2.4e-222 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
CFDIMMCL_02472 1e-212 iscS 2.8.1.7 E Cysteine desulfurase
CFDIMMCL_02473 7.8e-64 cymR K Transcriptional regulator
CFDIMMCL_02474 3.3e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
CFDIMMCL_02475 2.5e-138 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
CFDIMMCL_02476 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CFDIMMCL_02477 8.8e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
CFDIMMCL_02480 6.1e-280 lytH 3.5.1.28 M COG3103 SH3 domain protein
CFDIMMCL_02481 1.4e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CFDIMMCL_02482 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CFDIMMCL_02483 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CFDIMMCL_02484 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
CFDIMMCL_02485 5.2e-48 yrvD S Lipopolysaccharide assembly protein A domain
CFDIMMCL_02486 1.5e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
CFDIMMCL_02487 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CFDIMMCL_02488 1.3e-50 yrzD S Post-transcriptional regulator
CFDIMMCL_02489 7.2e-273 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CFDIMMCL_02490 9.5e-110 yrbG S membrane
CFDIMMCL_02491 2.4e-60 yrzE S Protein of unknown function (DUF3792)
CFDIMMCL_02492 3.3e-37 yajC U Preprotein translocase subunit YajC
CFDIMMCL_02493 1.4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
CFDIMMCL_02494 1.7e-193 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CFDIMMCL_02495 6.2e-20 yrzS S Protein of unknown function (DUF2905)
CFDIMMCL_02496 2.1e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
CFDIMMCL_02497 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
CFDIMMCL_02498 3.7e-93 bofC S BofC C-terminal domain
CFDIMMCL_02500 1.4e-46 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
CFDIMMCL_02501 3.9e-149 safA M spore coat assembly protein SafA
CFDIMMCL_02502 8.2e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CFDIMMCL_02503 6.7e-156 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
CFDIMMCL_02504 2.3e-303 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
CFDIMMCL_02505 8.3e-226 nifS 2.8.1.7 E Cysteine desulfurase
CFDIMMCL_02506 1.1e-95 niaR S small molecule binding protein (contains 3H domain)
CFDIMMCL_02507 1.2e-160 pheA 4.2.1.51 E Prephenate dehydratase
CFDIMMCL_02508 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
CFDIMMCL_02509 7.6e-236 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CFDIMMCL_02510 8.7e-107 spo0B T Sporulation initiation phospho-transferase B, C-terminal
CFDIMMCL_02511 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
CFDIMMCL_02512 3.2e-56 ysxB J ribosomal protein
CFDIMMCL_02513 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
CFDIMMCL_02514 1.2e-160 spoIVFB S Stage IV sporulation protein
CFDIMMCL_02515 8e-31 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
CFDIMMCL_02516 8.7e-103 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
CFDIMMCL_02517 8e-143 minD D Belongs to the ParA family
CFDIMMCL_02518 3.9e-98 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
CFDIMMCL_02519 1.4e-84 mreD M shape-determining protein
CFDIMMCL_02520 1.2e-157 mreC M Involved in formation and maintenance of cell shape
CFDIMMCL_02521 4e-184 mreB D Rod shape-determining protein MreB
CFDIMMCL_02522 1.8e-127 radC E Belongs to the UPF0758 family
CFDIMMCL_02523 2.4e-101 maf D septum formation protein Maf
CFDIMMCL_02524 1e-139 spoIIB S Sporulation related domain
CFDIMMCL_02525 3.5e-132 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
CFDIMMCL_02526 6.4e-243 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
CFDIMMCL_02527 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
CFDIMMCL_02528 2.1e-25
CFDIMMCL_02529 8.6e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CFDIMMCL_02530 3.5e-242 spoVID M stage VI sporulation protein D
CFDIMMCL_02531 1.2e-246 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
CFDIMMCL_02532 1e-184 hemB 4.2.1.24 H Belongs to the ALAD family
CFDIMMCL_02533 2.7e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
CFDIMMCL_02534 2.4e-175 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
CFDIMMCL_02535 3.6e-146 hemX O cytochrome C
CFDIMMCL_02536 1.4e-248 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CFDIMMCL_02537 1.5e-88 ysxD
CFDIMMCL_02538 8.8e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
CFDIMMCL_02539 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CFDIMMCL_02540 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
CFDIMMCL_02541 7.7e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CFDIMMCL_02542 4.7e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
CFDIMMCL_02543 2.4e-189 ysoA H Tetratricopeptide repeat
CFDIMMCL_02544 6.2e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CFDIMMCL_02545 6.3e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CFDIMMCL_02546 6.7e-201 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
CFDIMMCL_02547 5.3e-292 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CFDIMMCL_02548 2.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CFDIMMCL_02549 5.4e-84 ilvN 2.2.1.6 E Acetolactate synthase
CFDIMMCL_02550 0.0 ilvB 2.2.1.6 E Acetolactate synthase
CFDIMMCL_02555 4.8e-93 ysnB S Phosphoesterase
CFDIMMCL_02556 1.1e-101 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CFDIMMCL_02557 6.9e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CFDIMMCL_02558 2.8e-199 gerM S COG5401 Spore germination protein
CFDIMMCL_02559 2.7e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
CFDIMMCL_02560 7.4e-74 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
CFDIMMCL_02561 2e-30 gerE K Transcriptional regulator
CFDIMMCL_02562 2.4e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
CFDIMMCL_02563 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
CFDIMMCL_02564 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
CFDIMMCL_02565 4.8e-108 sdhC C succinate dehydrogenase
CFDIMMCL_02566 5.4e-80 yslB S Protein of unknown function (DUF2507)
CFDIMMCL_02567 2.9e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
CFDIMMCL_02568 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
CFDIMMCL_02569 2.5e-52 trxA O Belongs to the thioredoxin family
CFDIMMCL_02570 3e-305 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
CFDIMMCL_02571 2.9e-179 etfA C Electron transfer flavoprotein
CFDIMMCL_02572 2e-138 etfB C Electron transfer flavoprotein
CFDIMMCL_02573 1.3e-137 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
CFDIMMCL_02574 9.2e-104 fadR K Transcriptional regulator
CFDIMMCL_02575 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
CFDIMMCL_02576 1e-127 ywbB S Protein of unknown function (DUF2711)
CFDIMMCL_02577 4.7e-67 yshE S membrane
CFDIMMCL_02578 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
CFDIMMCL_02579 0.0 polX L COG1796 DNA polymerase IV (family X)
CFDIMMCL_02580 1.6e-83 cvpA S membrane protein, required for colicin V production
CFDIMMCL_02581 9.1e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CFDIMMCL_02582 2.2e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CFDIMMCL_02583 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CFDIMMCL_02584 1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CFDIMMCL_02585 3.7e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFDIMMCL_02586 2e-32 sspI S Belongs to the SspI family
CFDIMMCL_02587 2.4e-206 ysfB KT regulator
CFDIMMCL_02588 7.5e-261 glcD 1.1.3.15 C FAD binding domain
CFDIMMCL_02589 8.6e-259 glcF C Glycolate oxidase
CFDIMMCL_02590 0.0 cstA T Carbon starvation protein
CFDIMMCL_02591 6.2e-279 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
CFDIMMCL_02592 1.2e-144 araQ G transport system permease
CFDIMMCL_02593 2.9e-168 araP P PFAM binding-protein-dependent transport systems inner membrane component
CFDIMMCL_02594 1.8e-253 araN G carbohydrate transport
CFDIMMCL_02595 7.7e-227 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
CFDIMMCL_02596 1.1e-142 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
CFDIMMCL_02597 3.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
CFDIMMCL_02598 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
CFDIMMCL_02599 3.3e-299 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
CFDIMMCL_02600 1.8e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
CFDIMMCL_02601 8.1e-207 ysdC G COG1363 Cellulase M and related proteins
CFDIMMCL_02602 9.2e-68 ysdB S Sigma-w pathway protein YsdB
CFDIMMCL_02603 8.2e-44 ysdA S Membrane
CFDIMMCL_02604 4.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CFDIMMCL_02605 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
CFDIMMCL_02606 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CFDIMMCL_02607 1.7e-109 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
CFDIMMCL_02608 3.1e-40 lrgA S effector of murein hydrolase LrgA
CFDIMMCL_02609 3.8e-131 lytT T COG3279 Response regulator of the LytR AlgR family
CFDIMMCL_02610 0.0 lytS 2.7.13.3 T Histidine kinase
CFDIMMCL_02611 5.5e-152 ysaA S HAD-hyrolase-like
CFDIMMCL_02612 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CFDIMMCL_02613 2.5e-155 ytxC S YtxC-like family
CFDIMMCL_02614 9.3e-110 ytxB S SNARE associated Golgi protein
CFDIMMCL_02615 4.3e-172 dnaI L Primosomal protein DnaI
CFDIMMCL_02616 4.5e-258 dnaB L Membrane attachment protein
CFDIMMCL_02617 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CFDIMMCL_02618 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CFDIMMCL_02619 1.4e-195 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CFDIMMCL_02620 2e-67 ytcD K Transcriptional regulator
CFDIMMCL_02621 1.2e-206 ytbD EGP Major facilitator Superfamily
CFDIMMCL_02622 5.2e-161 ytbE S reductase
CFDIMMCL_02623 4.7e-100 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CFDIMMCL_02624 9.5e-107 ytaF P Probably functions as a manganese efflux pump
CFDIMMCL_02625 4.1e-158 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
CFDIMMCL_02626 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFDIMMCL_02627 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
CFDIMMCL_02628 5.3e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CFDIMMCL_02629 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
CFDIMMCL_02630 3.1e-242 icd 1.1.1.42 C isocitrate
CFDIMMCL_02631 1.6e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
CFDIMMCL_02632 7.7e-49 yjdF S Protein of unknown function (DUF2992)
CFDIMMCL_02633 1.1e-72 yeaL S membrane
CFDIMMCL_02634 3.6e-194 ytvI S sporulation integral membrane protein YtvI
CFDIMMCL_02635 1.6e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
CFDIMMCL_02636 6.8e-296 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
CFDIMMCL_02637 6.8e-181 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
CFDIMMCL_02638 6.2e-182 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
CFDIMMCL_02639 6.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CFDIMMCL_02640 2.6e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
CFDIMMCL_02641 0.0 dnaE 2.7.7.7 L DNA polymerase
CFDIMMCL_02642 3.2e-56 ytrH S Sporulation protein YtrH
CFDIMMCL_02643 5.1e-87 ytrI
CFDIMMCL_02644 4.4e-23
CFDIMMCL_02645 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
CFDIMMCL_02646 8.2e-48 ytpI S YtpI-like protein
CFDIMMCL_02647 7.5e-239 ytoI K transcriptional regulator containing CBS domains
CFDIMMCL_02648 1.1e-129 ytkL S Belongs to the UPF0173 family
CFDIMMCL_02649 4.5e-143 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CFDIMMCL_02651 1.8e-264 argH 4.3.2.1 E argininosuccinate lyase
CFDIMMCL_02652 1.5e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
CFDIMMCL_02653 2.1e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
CFDIMMCL_02654 4.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CFDIMMCL_02655 3.6e-185 ytxK 2.1.1.72 L DNA methylase
CFDIMMCL_02656 4.9e-90 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CFDIMMCL_02657 1.6e-60 ytfJ S Sporulation protein YtfJ
CFDIMMCL_02658 1.1e-119 ytfI S Protein of unknown function (DUF2953)
CFDIMMCL_02659 4.5e-88 yteJ S RDD family
CFDIMMCL_02660 2.9e-182 sppA OU signal peptide peptidase SppA
CFDIMMCL_02661 1.5e-152 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CFDIMMCL_02662 0.0 ytcJ S amidohydrolase
CFDIMMCL_02663 1.6e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
CFDIMMCL_02664 3.9e-31 sspB S spore protein
CFDIMMCL_02665 1.4e-201 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CFDIMMCL_02666 1.7e-210 iscS2 2.8.1.7 E Cysteine desulfurase
CFDIMMCL_02667 1.8e-240 braB E Component of the transport system for branched-chain amino acids
CFDIMMCL_02668 1e-264 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CFDIMMCL_02669 1.9e-155 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
CFDIMMCL_02670 4.1e-110 yttP K Transcriptional regulator
CFDIMMCL_02671 1.1e-86 ytsP 1.8.4.14 T GAF domain-containing protein
CFDIMMCL_02672 9.2e-285 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
CFDIMMCL_02673 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CFDIMMCL_02674 6.6e-246 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
CFDIMMCL_02675 2.7e-105 yokH G SMI1 / KNR4 family
CFDIMMCL_02677 1.3e-102
CFDIMMCL_02679 1.2e-88 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
CFDIMMCL_02681 1.4e-28 S Phage-like element PBSX protein XtrA
CFDIMMCL_02682 5.2e-30
CFDIMMCL_02683 1.8e-33 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
CFDIMMCL_02684 2.3e-223 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CFDIMMCL_02685 7.3e-09
CFDIMMCL_02686 2e-91 yhbO 1.11.1.6, 3.5.1.124 S protease
CFDIMMCL_02688 2.4e-141 E GDSL-like Lipase/Acylhydrolase family
CFDIMMCL_02689 5.1e-151 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CFDIMMCL_02690 4.4e-149 K Transcriptional regulator
CFDIMMCL_02691 5.2e-125 azlC E AzlC protein
CFDIMMCL_02692 8.7e-48 azlD S Branched-chain amino acid transport protein (AzlD)
CFDIMMCL_02693 4.2e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CFDIMMCL_02694 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
CFDIMMCL_02695 2.8e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
CFDIMMCL_02696 2.5e-118 acuB S Domain in cystathionine beta-synthase and other proteins.
CFDIMMCL_02697 2.3e-231 acuC BQ histone deacetylase
CFDIMMCL_02698 7.4e-121 motS N Flagellar motor protein
CFDIMMCL_02699 5.6e-80 motA N flagellar motor
CFDIMMCL_02700 8.3e-55 motA N flagellar motor
CFDIMMCL_02701 2.9e-182 ccpA K catabolite control protein A
CFDIMMCL_02702 1.9e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
CFDIMMCL_02703 1.7e-43 ytxJ O Protein of unknown function (DUF2847)
CFDIMMCL_02704 1.7e-16 ytxH S COG4980 Gas vesicle protein
CFDIMMCL_02705 1.7e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CFDIMMCL_02706 9.9e-252 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
CFDIMMCL_02707 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
CFDIMMCL_02708 1.1e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CFDIMMCL_02709 3.7e-148 ytpQ S Belongs to the UPF0354 family
CFDIMMCL_02710 1.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
CFDIMMCL_02711 2.7e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
CFDIMMCL_02712 5.8e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
CFDIMMCL_02713 1.7e-51 ytzB S small secreted protein
CFDIMMCL_02714 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
CFDIMMCL_02715 7.1e-166 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
CFDIMMCL_02716 8e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
CFDIMMCL_02717 9.2e-46 ytzH S YtzH-like protein
CFDIMMCL_02718 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
CFDIMMCL_02719 7.7e-182 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
CFDIMMCL_02720 9.5e-172 ytlQ
CFDIMMCL_02721 2.8e-102 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CFDIMMCL_02722 1.3e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
CFDIMMCL_02723 1.4e-272 pepV 3.5.1.18 E Dipeptidase
CFDIMMCL_02724 4.1e-229 pbuO S permease
CFDIMMCL_02725 1.5e-219 ythQ U Bacterial ABC transporter protein EcsB
CFDIMMCL_02726 3.4e-129 ythP V ABC transporter
CFDIMMCL_02727 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
CFDIMMCL_02728 1.7e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CFDIMMCL_02729 2e-294 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CFDIMMCL_02730 3.1e-210 ytfP S HI0933-like protein
CFDIMMCL_02731 4.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
CFDIMMCL_02732 9e-26 yteV S Sporulation protein Cse60
CFDIMMCL_02733 3e-187 msmR K Transcriptional regulator
CFDIMMCL_02734 1.1e-247 msmE G Bacterial extracellular solute-binding protein
CFDIMMCL_02735 3.3e-169 amyD G Binding-protein-dependent transport system inner membrane component
CFDIMMCL_02736 4.8e-143 amyC P ABC transporter (permease)
CFDIMMCL_02737 4e-253 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
CFDIMMCL_02738 2.4e-86 M Acetyltransferase (GNAT) domain
CFDIMMCL_02739 5.6e-52 ytwF P Sulfurtransferase
CFDIMMCL_02740 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
CFDIMMCL_02741 1.2e-52 ytvB S Protein of unknown function (DUF4257)
CFDIMMCL_02742 6.6e-140 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
CFDIMMCL_02743 5.6e-209 yttB EGP Major facilitator Superfamily
CFDIMMCL_02744 1.7e-131 ywaF S Integral membrane protein
CFDIMMCL_02745 0.0 bceB V ABC transporter (permease)
CFDIMMCL_02746 5.8e-135 bceA V ABC transporter, ATP-binding protein
CFDIMMCL_02747 1.3e-171 T PhoQ Sensor
CFDIMMCL_02748 2e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CFDIMMCL_02749 3.7e-222 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
CFDIMMCL_02750 1.3e-125 ytrE V ABC transporter, ATP-binding protein
CFDIMMCL_02751 2.5e-162
CFDIMMCL_02752 2.7e-155 P ABC-2 family transporter protein
CFDIMMCL_02753 1.9e-174 S ABC-2 family transporter protein
CFDIMMCL_02754 3.8e-162 ytrB P abc transporter atp-binding protein
CFDIMMCL_02755 3.9e-66 ytrA K GntR family transcriptional regulator
CFDIMMCL_02757 7.4e-40 ytzC S Protein of unknown function (DUF2524)
CFDIMMCL_02758 0.0 IQ AMP-binding enzyme
CFDIMMCL_02759 7.1e-144 K helix_turn_helix, Arsenical Resistance Operon Repressor
CFDIMMCL_02760 3.1e-37 K helix_turn_helix, Arsenical Resistance Operon Repressor
CFDIMMCL_02761 0.0 Q Polyketide synthase of type I
CFDIMMCL_02762 3e-105 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFDIMMCL_02763 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFDIMMCL_02764 2.1e-282 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFDIMMCL_02765 1.8e-107 C Nitroreductase
CFDIMMCL_02766 4.2e-53 C Nitroreductase
CFDIMMCL_02767 1.1e-132 nrsA Q Thioesterase domain
CFDIMMCL_02768 2.2e-288 norB EGP COG0477 Permeases of the major facilitator superfamily
CFDIMMCL_02769 2.1e-190 yhcC S Fe-S oxidoreductase
CFDIMMCL_02770 3.9e-107 ytqB J Putative rRNA methylase
CFDIMMCL_02772 8.6e-145 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
CFDIMMCL_02773 4.4e-213 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
CFDIMMCL_02774 2.9e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
CFDIMMCL_02775 2.3e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CFDIMMCL_02776 1.9e-261 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
CFDIMMCL_02777 0.0 asnB 6.3.5.4 E Asparagine synthase
CFDIMMCL_02778 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CFDIMMCL_02779 1.3e-309 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CFDIMMCL_02780 1.6e-38 ytmB S Protein of unknown function (DUF2584)
CFDIMMCL_02781 3.2e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
CFDIMMCL_02782 6.6e-187 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
CFDIMMCL_02783 2.9e-145 ytlC P ABC transporter
CFDIMMCL_02784 5.8e-141 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
CFDIMMCL_02785 9.8e-88 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
CFDIMMCL_02786 6e-62 ytkC S Bacteriophage holin family
CFDIMMCL_02787 3.2e-77 dps P Belongs to the Dps family
CFDIMMCL_02789 7.2e-77 ytkA S YtkA-like
CFDIMMCL_02790 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
CFDIMMCL_02791 6.2e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
CFDIMMCL_02792 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
CFDIMMCL_02793 1.6e-41 rpmE2 J Ribosomal protein L31
CFDIMMCL_02794 6.8e-240 cydA 1.10.3.14 C oxidase, subunit
CFDIMMCL_02795 4e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
CFDIMMCL_02796 2.3e-24 S Domain of Unknown Function (DUF1540)
CFDIMMCL_02797 1.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
CFDIMMCL_02798 3.3e-280 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
CFDIMMCL_02799 2.4e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CFDIMMCL_02800 1.7e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
CFDIMMCL_02801 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CFDIMMCL_02802 3.1e-275 menF 5.4.4.2 HQ Isochorismate synthase
CFDIMMCL_02803 2e-132 dksA T COG1734 DnaK suppressor protein
CFDIMMCL_02804 6.2e-79 tspO T membrane
CFDIMMCL_02811 7.8e-08
CFDIMMCL_02812 1.3e-09
CFDIMMCL_02819 1.6e-08
CFDIMMCL_02824 3.4e-39 S COG NOG14552 non supervised orthologous group
CFDIMMCL_02825 3.3e-98 thiT S Thiamine transporter protein (Thia_YuaJ)
CFDIMMCL_02826 7e-180 yuaG 3.4.21.72 S protein conserved in bacteria
CFDIMMCL_02827 1.3e-85 yuaF OU Membrane protein implicated in regulation of membrane protease activity
CFDIMMCL_02828 5.1e-84 yuaE S DinB superfamily
CFDIMMCL_02829 6.5e-110 yuaD S MOSC domain
CFDIMMCL_02830 7.1e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
CFDIMMCL_02831 1.2e-285 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
CFDIMMCL_02832 2.7e-97 yuaC K Belongs to the GbsR family
CFDIMMCL_02833 2.1e-94 yuaB
CFDIMMCL_02834 1.1e-121 ktrA P COG0569 K transport systems, NAD-binding component
CFDIMMCL_02835 6.7e-148 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CFDIMMCL_02836 2.4e-220 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CFDIMMCL_02837 1.3e-124 G Cupin
CFDIMMCL_02838 6.2e-54 yjcN
CFDIMMCL_02840 2.3e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
CFDIMMCL_02841 9e-196 yubA S transporter activity
CFDIMMCL_02842 1.9e-186 ygjR S Oxidoreductase
CFDIMMCL_02843 5.1e-98 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
CFDIMMCL_02845 1.6e-239 mcpA NT chemotaxis protein
CFDIMMCL_02846 1.1e-225 mcpA NT chemotaxis protein
CFDIMMCL_02847 1.9e-241 mcpA NT chemotaxis protein
CFDIMMCL_02848 1.7e-223 mcpA NT chemotaxis protein
CFDIMMCL_02849 9e-141 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
CFDIMMCL_02850 4.8e-41
CFDIMMCL_02851 1.8e-192 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
CFDIMMCL_02852 2.8e-78 yugU S Uncharacterised protein family UPF0047
CFDIMMCL_02853 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
CFDIMMCL_02854 3e-232 yugS S COG1253 Hemolysins and related proteins containing CBS domains
CFDIMMCL_02855 8.3e-117 yugP S Zn-dependent protease
CFDIMMCL_02856 4.5e-18
CFDIMMCL_02857 1.1e-26 mstX S Membrane-integrating protein Mistic
CFDIMMCL_02858 6.3e-182 yugO P COG1226 Kef-type K transport systems
CFDIMMCL_02859 1.3e-72 yugN S YugN-like family
CFDIMMCL_02861 8.7e-259 pgi 5.3.1.9 G Belongs to the GPI family
CFDIMMCL_02862 2.1e-97 S NADPH-dependent FMN reductase
CFDIMMCL_02863 6.5e-119 ycaC Q Isochorismatase family
CFDIMMCL_02864 7.4e-230 yugK C Dehydrogenase
CFDIMMCL_02865 1.2e-227 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
CFDIMMCL_02866 8.6e-59 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
CFDIMMCL_02867 1.2e-211 yugH 2.6.1.1 E Aminotransferase
CFDIMMCL_02868 2e-83 alaR K Transcriptional regulator
CFDIMMCL_02869 3.8e-156 yugF I Hydrolase
CFDIMMCL_02870 1.4e-40 yugE S Domain of unknown function (DUF1871)
CFDIMMCL_02871 8.4e-226 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
CFDIMMCL_02872 5.6e-231 T PhoQ Sensor
CFDIMMCL_02873 3.7e-69 kapB G Kinase associated protein B
CFDIMMCL_02874 4.5e-118 kapD L the KinA pathway to sporulation
CFDIMMCL_02875 1.5e-185 yuxJ EGP Major facilitator Superfamily
CFDIMMCL_02876 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
CFDIMMCL_02877 1.7e-72 yuxK S protein conserved in bacteria
CFDIMMCL_02878 9.3e-74 yufK S Family of unknown function (DUF5366)
CFDIMMCL_02879 1.7e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
CFDIMMCL_02880 2.7e-126 dcuR T COG4565 Response regulator of citrate malate metabolism
CFDIMMCL_02881 8.3e-196 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
CFDIMMCL_02882 1.5e-261 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
CFDIMMCL_02883 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
CFDIMMCL_02884 1.6e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
CFDIMMCL_02885 1.8e-12
CFDIMMCL_02886 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
CFDIMMCL_02887 1.8e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CFDIMMCL_02888 8.9e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CFDIMMCL_02889 1.2e-264 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CFDIMMCL_02890 5.3e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CFDIMMCL_02891 1.1e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CFDIMMCL_02892 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
CFDIMMCL_02893 3.2e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
CFDIMMCL_02894 1.8e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CFDIMMCL_02895 0.0 comP 2.7.13.3 T Histidine kinase
CFDIMMCL_02897 2.4e-142 comQ H Polyprenyl synthetase
CFDIMMCL_02899 3e-54 yuzC
CFDIMMCL_02900 4.1e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
CFDIMMCL_02901 2.5e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CFDIMMCL_02902 1.1e-103 pncA Q COG1335 Amidases related to nicotinamidase
CFDIMMCL_02903 7.2e-68 yueI S Protein of unknown function (DUF1694)
CFDIMMCL_02904 2.8e-38 yueH S YueH-like protein
CFDIMMCL_02905 6.4e-34 yueG S Spore germination protein gerPA/gerPF
CFDIMMCL_02906 3e-188 yueF S transporter activity
CFDIMMCL_02907 1.6e-22 S Protein of unknown function (DUF2642)
CFDIMMCL_02908 3.7e-96 yueE S phosphohydrolase
CFDIMMCL_02909 5.8e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CFDIMMCL_02910 1.8e-78 yueC S Family of unknown function (DUF5383)
CFDIMMCL_02911 0.0 esaA S type VII secretion protein EsaA
CFDIMMCL_02912 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
CFDIMMCL_02913 7.4e-207 essB S WXG100 protein secretion system (Wss), protein YukC
CFDIMMCL_02914 3.9e-40 yukD S WXG100 protein secretion system (Wss), protein YukD
CFDIMMCL_02915 3.3e-46 esxA S Belongs to the WXG100 family
CFDIMMCL_02916 4.5e-230 yukF QT Transcriptional regulator
CFDIMMCL_02917 1e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
CFDIMMCL_02918 6.8e-135 yukJ S Uncharacterized conserved protein (DUF2278)
CFDIMMCL_02919 1.3e-36 mbtH S MbtH-like protein
CFDIMMCL_02920 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFDIMMCL_02921 6.3e-176 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
CFDIMMCL_02922 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
CFDIMMCL_02923 1.1e-225 entC 5.4.4.2 HQ Isochorismate synthase
CFDIMMCL_02924 1.1e-136 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CFDIMMCL_02925 1.5e-166 besA S Putative esterase
CFDIMMCL_02926 1.1e-120 yuiH S Oxidoreductase molybdopterin binding domain
CFDIMMCL_02927 1.1e-101 bioY S Biotin biosynthesis protein
CFDIMMCL_02928 3.7e-209 yuiF S antiporter
CFDIMMCL_02929 4e-281 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CFDIMMCL_02930 9.1e-78 yuiD S protein conserved in bacteria
CFDIMMCL_02931 1.4e-118 yuiC S protein conserved in bacteria
CFDIMMCL_02932 9.9e-28 yuiB S Putative membrane protein
CFDIMMCL_02933 1.1e-236 yumB 1.6.99.3 C NADH dehydrogenase
CFDIMMCL_02934 5e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
CFDIMMCL_02936 2.1e-154 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CFDIMMCL_02937 7e-22 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CFDIMMCL_02938 4.8e-29
CFDIMMCL_02939 3.7e-72 CP Membrane
CFDIMMCL_02940 1.5e-124 V ABC transporter
CFDIMMCL_02942 2.9e-33 S Bacteriocin class IId cyclical uberolysin-like
CFDIMMCL_02944 2.9e-96 rimJ 2.3.1.128 J Alanine acetyltransferase
CFDIMMCL_02945 7.8e-140 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
CFDIMMCL_02946 1.1e-62 erpA S Belongs to the HesB IscA family
CFDIMMCL_02947 5.7e-163 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CFDIMMCL_02948 1.7e-213 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CFDIMMCL_02949 2.4e-39 yuzB S Belongs to the UPF0349 family
CFDIMMCL_02950 8.5e-209 yutJ 1.6.99.3 C NADH dehydrogenase
CFDIMMCL_02951 4.7e-57 yuzD S protein conserved in bacteria
CFDIMMCL_02952 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
CFDIMMCL_02953 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
CFDIMMCL_02954 1e-170 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
CFDIMMCL_02955 4e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CFDIMMCL_02956 1.9e-234 hom 1.1.1.3 E homoserine dehydrogenase
CFDIMMCL_02957 1.4e-197 yutH S Spore coat protein
CFDIMMCL_02958 3e-85 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
CFDIMMCL_02959 8.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
CFDIMMCL_02960 8.5e-67 yutE S Protein of unknown function DUF86
CFDIMMCL_02961 1.7e-47 yutD S protein conserved in bacteria
CFDIMMCL_02962 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CFDIMMCL_02963 5.8e-196 lytH M Peptidase, M23
CFDIMMCL_02964 6e-132 yunB S Sporulation protein YunB (Spo_YunB)
CFDIMMCL_02965 2.3e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
CFDIMMCL_02966 1.8e-145 yunE S membrane transporter protein
CFDIMMCL_02967 1.3e-170 yunF S Protein of unknown function DUF72
CFDIMMCL_02968 4.7e-63 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
CFDIMMCL_02969 8.8e-267 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
CFDIMMCL_02970 2.1e-304 pucR QT COG2508 Regulator of polyketide synthase expression
CFDIMMCL_02971 4.3e-74
CFDIMMCL_02973 1.5e-214 blt EGP Major facilitator Superfamily
CFDIMMCL_02974 4.9e-240 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
CFDIMMCL_02975 1.9e-239 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
CFDIMMCL_02976 1.1e-169 bsn L Ribonuclease
CFDIMMCL_02977 2.3e-209 msmX P Belongs to the ABC transporter superfamily
CFDIMMCL_02978 1.2e-134 yurK K UTRA
CFDIMMCL_02979 6.3e-162 yurL 2.7.1.218 G pfkB family carbohydrate kinase
CFDIMMCL_02980 1.4e-164 yurM P COG0395 ABC-type sugar transport system, permease component
CFDIMMCL_02981 1.2e-158 yurN G Binding-protein-dependent transport system inner membrane component
CFDIMMCL_02982 3.3e-247 yurO G COG1653 ABC-type sugar transport system, periplasmic component
CFDIMMCL_02983 1.9e-186 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
CFDIMMCL_02984 1.2e-166 K helix_turn_helix, mercury resistance
CFDIMMCL_02987 3.1e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
CFDIMMCL_02988 3.2e-206 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
CFDIMMCL_02989 1.8e-130 Q ubiE/COQ5 methyltransferase family
CFDIMMCL_02990 1.5e-85 yncE S Protein of unknown function (DUF2691)
CFDIMMCL_02991 2e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
CFDIMMCL_02992 3e-270 sufB O FeS cluster assembly
CFDIMMCL_02993 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
CFDIMMCL_02994 2.1e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CFDIMMCL_02995 7e-245 sufD O assembly protein SufD
CFDIMMCL_02996 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
CFDIMMCL_02997 7.6e-64 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CFDIMMCL_02998 2.3e-145 metQ P Belongs to the NlpA lipoprotein family
CFDIMMCL_02999 1.8e-95 metI P COG2011 ABC-type metal ion transport system, permease component
CFDIMMCL_03000 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CFDIMMCL_03001 5e-57 yusD S SCP-2 sterol transfer family
CFDIMMCL_03002 1.6e-54 yusE CO Thioredoxin
CFDIMMCL_03003 2.2e-63 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
CFDIMMCL_03004 1.3e-40 yusG S Protein of unknown function (DUF2553)
CFDIMMCL_03005 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
CFDIMMCL_03006 2.1e-63 arsC 1.20.4.1 P Belongs to the ArsC family
CFDIMMCL_03007 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
CFDIMMCL_03008 1.1e-217 fadA 2.3.1.16 I Belongs to the thiolase family
CFDIMMCL_03009 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
CFDIMMCL_03010 3.6e-168 fadM E Proline dehydrogenase
CFDIMMCL_03011 1.4e-43
CFDIMMCL_03012 1.1e-53 yusN M Coat F domain
CFDIMMCL_03013 5.7e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
CFDIMMCL_03014 8.1e-288 yusP P Major facilitator superfamily
CFDIMMCL_03015 3.1e-68 yusQ S Tautomerase enzyme
CFDIMMCL_03016 1.4e-133 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CFDIMMCL_03017 1e-159 yusT K LysR substrate binding domain
CFDIMMCL_03018 4.2e-161 ywbI2 K Transcriptional regulator
CFDIMMCL_03019 4.1e-141 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
CFDIMMCL_03020 1.7e-190 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CFDIMMCL_03021 3.3e-39 yusU S Protein of unknown function (DUF2573)
CFDIMMCL_03022 1.4e-150 yusV 3.6.3.34 HP ABC transporter
CFDIMMCL_03023 7.2e-45 S YusW-like protein
CFDIMMCL_03024 0.0 pepF2 E COG1164 Oligoendopeptidase F
CFDIMMCL_03025 9.6e-155 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CFDIMMCL_03026 6.7e-81 dps P Belongs to the Dps family
CFDIMMCL_03027 7.5e-242 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFDIMMCL_03028 2.6e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CFDIMMCL_03029 2.5e-253 cssS 2.7.13.3 T PhoQ Sensor
CFDIMMCL_03030 3.4e-24
CFDIMMCL_03031 2.7e-158 yuxN K Transcriptional regulator
CFDIMMCL_03032 3.9e-262 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
CFDIMMCL_03033 6.6e-24 S Protein of unknown function (DUF3970)
CFDIMMCL_03034 1.1e-259 gerAA EG Spore germination protein
CFDIMMCL_03035 2e-189 gerAB E Spore germination protein
CFDIMMCL_03036 7.3e-211 gerAC S Spore germination B3/ GerAC like, C-terminal
CFDIMMCL_03037 1.5e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CFDIMMCL_03038 1e-193 vraS 2.7.13.3 T Histidine kinase
CFDIMMCL_03039 1.7e-128 yvqF S Cell wall-active antibiotics response 4TMS YvqF
CFDIMMCL_03040 2.7e-144 liaG S Putative adhesin
CFDIMMCL_03041 1.5e-94 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
CFDIMMCL_03042 3.3e-46 liaI S membrane
CFDIMMCL_03043 4.7e-230 yvqJ EGP Major facilitator Superfamily
CFDIMMCL_03044 3.7e-102 yvqK 2.5.1.17 S Adenosyltransferase
CFDIMMCL_03045 2.1e-227 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
CFDIMMCL_03046 6.7e-182 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFDIMMCL_03047 1.1e-167 yvrC P ABC transporter substrate-binding protein
CFDIMMCL_03048 1.1e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CFDIMMCL_03049 2e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
CFDIMMCL_03050 0.0 T PhoQ Sensor
CFDIMMCL_03051 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CFDIMMCL_03052 9.9e-103 yvrI K RNA polymerase
CFDIMMCL_03053 1.6e-15 S YvrJ protein family
CFDIMMCL_03054 5.4e-233 oxdC 4.1.1.2 G Oxalate decarboxylase
CFDIMMCL_03055 4.4e-68 yvrL S Regulatory protein YrvL
CFDIMMCL_03056 4.8e-148 fhuC 3.6.3.34 HP ABC transporter
CFDIMMCL_03057 1.1e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFDIMMCL_03058 6.6e-185 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFDIMMCL_03059 4e-178 fhuD P ABC transporter
CFDIMMCL_03060 1.3e-236 yvsH E Arginine ornithine antiporter
CFDIMMCL_03061 1e-13 S Small spore protein J (Spore_SspJ)
CFDIMMCL_03062 1.3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
CFDIMMCL_03063 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
CFDIMMCL_03064 1.8e-167 yvgK P COG1910 Periplasmic molybdate-binding protein domain
CFDIMMCL_03065 2.2e-140 modA P COG0725 ABC-type molybdate transport system, periplasmic component
CFDIMMCL_03066 2.7e-99 modB P COG4149 ABC-type molybdate transport system, permease component
CFDIMMCL_03067 4.4e-115 yfiK K Regulator
CFDIMMCL_03068 4.9e-183 T Histidine kinase
CFDIMMCL_03069 1.9e-172 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
CFDIMMCL_03070 2.5e-195 yfiM V ABC-2 type transporter
CFDIMMCL_03071 1.4e-201 yfiN V COG0842 ABC-type multidrug transport system, permease component
CFDIMMCL_03072 5e-156 yvgN S reductase
CFDIMMCL_03073 4.9e-87 yvgO
CFDIMMCL_03074 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
CFDIMMCL_03075 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
CFDIMMCL_03076 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CFDIMMCL_03077 0.0 helD 3.6.4.12 L DNA helicase
CFDIMMCL_03078 9.1e-107 yvgT S membrane
CFDIMMCL_03079 6.1e-143 S Metallo-peptidase family M12
CFDIMMCL_03080 2e-73 bdbC O Required for disulfide bond formation in some proteins
CFDIMMCL_03081 1.2e-102 bdbD O Thioredoxin
CFDIMMCL_03082 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
CFDIMMCL_03083 0.0 copA 3.6.3.54 P P-type ATPase
CFDIMMCL_03084 2.6e-29 copZ P Heavy-metal-associated domain
CFDIMMCL_03085 3.7e-48 csoR S transcriptional
CFDIMMCL_03086 7.3e-197 yvaA 1.1.1.371 S Oxidoreductase
CFDIMMCL_03087 1.1e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CFDIMMCL_03088 1.1e-163 K Helix-turn-helix XRE-family like proteins
CFDIMMCL_03089 2.9e-221 ynfM EGP Major Facilitator Superfamily
CFDIMMCL_03090 1.2e-70 4.1.1.44 S Carboxymuconolactone decarboxylase family
CFDIMMCL_03091 1.4e-147 S Amidohydrolase
CFDIMMCL_03092 4.7e-257 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFDIMMCL_03093 5.9e-48 ytnI O COG0695 Glutaredoxin and related proteins
CFDIMMCL_03094 2.9e-182 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFDIMMCL_03095 6.6e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
CFDIMMCL_03096 1.3e-120 tcyM U Binding-protein-dependent transport system inner membrane component
CFDIMMCL_03097 1.4e-122 tcyL P Binding-protein-dependent transport system inner membrane component
CFDIMMCL_03098 9.9e-149 tcyK M Bacterial periplasmic substrate-binding proteins
CFDIMMCL_03099 7.4e-132 ytmJ ET Bacterial periplasmic substrate-binding proteins
CFDIMMCL_03100 1.7e-101 ytmI K Acetyltransferase (GNAT) domain
CFDIMMCL_03101 4.8e-165 ytlI K LysR substrate binding domain
CFDIMMCL_03102 1.1e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CFDIMMCL_03103 2.9e-53 yrdF K ribonuclease inhibitor
CFDIMMCL_03105 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CFDIMMCL_03106 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
CFDIMMCL_03107 7.4e-143 est 3.1.1.1 S Carboxylesterase
CFDIMMCL_03108 4.8e-24 secG U Preprotein translocase subunit SecG
CFDIMMCL_03109 6e-35 yvzC K Transcriptional
CFDIMMCL_03110 4e-66 K transcriptional
CFDIMMCL_03111 2.7e-73 yvaO K Cro/C1-type HTH DNA-binding domain
CFDIMMCL_03112 8.8e-53 yodB K transcriptional
CFDIMMCL_03113 2.2e-260 T His Kinase A (phosphoacceptor) domain
CFDIMMCL_03114 2e-123 K Transcriptional regulatory protein, C terminal
CFDIMMCL_03115 1.9e-141 mutG S ABC-2 family transporter protein
CFDIMMCL_03116 2.5e-127 spaE S ABC-2 family transporter protein
CFDIMMCL_03117 2.5e-127 mutF V ABC transporter, ATP-binding protein
CFDIMMCL_03118 3.6e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
CFDIMMCL_03119 2.6e-174 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
CFDIMMCL_03120 5.4e-113 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
CFDIMMCL_03121 3.4e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
CFDIMMCL_03122 4.3e-76 yvbF K Belongs to the GbsR family
CFDIMMCL_03123 3.4e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
CFDIMMCL_03124 2.2e-173 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
CFDIMMCL_03125 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
CFDIMMCL_03126 6.7e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
CFDIMMCL_03127 1.9e-98 yvbF K Belongs to the GbsR family
CFDIMMCL_03128 5.2e-105 yvbG U UPF0056 membrane protein
CFDIMMCL_03129 4.5e-121 exoY M Membrane
CFDIMMCL_03130 0.0 tcaA S response to antibiotic
CFDIMMCL_03131 3.8e-81 yvbK 3.1.3.25 K acetyltransferase
CFDIMMCL_03132 3.5e-214 EGP Major facilitator Superfamily
CFDIMMCL_03133 2.2e-181
CFDIMMCL_03134 1.2e-126 S GlcNAc-PI de-N-acetylase
CFDIMMCL_03135 2.5e-143 C WbqC-like protein family
CFDIMMCL_03136 1.2e-150 M Protein involved in cellulose biosynthesis
CFDIMMCL_03137 2.2e-240 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CFDIMMCL_03138 8.6e-173 5.1.3.2 M GDP-mannose 4,6 dehydratase
CFDIMMCL_03139 1.3e-218 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
CFDIMMCL_03140 2.1e-162 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CFDIMMCL_03141 2.9e-79 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CFDIMMCL_03142 7.8e-241 ywaD 3.4.11.10, 3.4.11.6 S PA domain
CFDIMMCL_03143 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CFDIMMCL_03144 7.5e-299 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
CFDIMMCL_03145 6.6e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CFDIMMCL_03146 1.7e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
CFDIMMCL_03147 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CFDIMMCL_03148 2.3e-187 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
CFDIMMCL_03150 7.4e-253 araE EGP Major facilitator Superfamily
CFDIMMCL_03151 3.4e-205 araR K transcriptional
CFDIMMCL_03152 6.4e-190 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFDIMMCL_03154 2.1e-157 yvbU K Transcriptional regulator
CFDIMMCL_03155 3.5e-156 yvbV EG EamA-like transporter family
CFDIMMCL_03156 1.7e-214 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
CFDIMMCL_03157 4e-261
CFDIMMCL_03158 1.7e-184 purR7 5.1.1.1 K Transcriptional regulator
CFDIMMCL_03159 6.9e-116 yyaS S Membrane
CFDIMMCL_03160 6.1e-168 3.1.3.104 S hydrolases of the HAD superfamily
CFDIMMCL_03161 9.1e-153 ybbH_1 K RpiR family transcriptional regulator
CFDIMMCL_03162 3.2e-297 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
CFDIMMCL_03163 4.3e-226 gntP EG COG2610 H gluconate symporter and related permeases
CFDIMMCL_03164 3.6e-134 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
CFDIMMCL_03165 1.6e-271 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
CFDIMMCL_03166 1.1e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
CFDIMMCL_03167 2e-227 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CFDIMMCL_03168 1.6e-121 yvfI K COG2186 Transcriptional regulators
CFDIMMCL_03169 2.4e-295 yvfH C L-lactate permease
CFDIMMCL_03170 1.8e-245 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
CFDIMMCL_03171 1.6e-32 yvfG S YvfG protein
CFDIMMCL_03172 3.6e-190 yvfF GM Exopolysaccharide biosynthesis protein
CFDIMMCL_03173 5.7e-222 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
CFDIMMCL_03174 1.1e-57 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
CFDIMMCL_03175 3.4e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
CFDIMMCL_03176 8.2e-274 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CFDIMMCL_03177 7.8e-199 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
CFDIMMCL_03178 4.7e-207 epsI GM pyruvyl transferase
CFDIMMCL_03179 1.2e-196 epsH GT2 S Glycosyltransferase like family 2
CFDIMMCL_03180 4.1e-206 epsG S EpsG family
CFDIMMCL_03181 3.1e-217 epsF GT4 M Glycosyl transferases group 1
CFDIMMCL_03182 1.8e-161 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
CFDIMMCL_03183 1.7e-223 epsD GT4 M Glycosyl transferase 4-like
CFDIMMCL_03184 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
CFDIMMCL_03185 1.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
CFDIMMCL_03186 1.2e-104 ywqC M biosynthesis protein
CFDIMMCL_03187 5.1e-78 slr K transcriptional
CFDIMMCL_03188 1.6e-287 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
CFDIMMCL_03189 1.4e-98 ywjB H RibD C-terminal domain
CFDIMMCL_03190 4e-113 yyaS S Membrane
CFDIMMCL_03191 6.4e-93 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CFDIMMCL_03192 5.5e-94 padC Q Phenolic acid decarboxylase
CFDIMMCL_03193 2e-16 S Protein of unknown function (DUF1433)
CFDIMMCL_03194 4.8e-41 S Protein of unknown function (DUF1433)
CFDIMMCL_03195 1.6e-46 I Pfam Lipase (class 3)
CFDIMMCL_03196 1.8e-16 S Protein of unknown function (DUF1433)
CFDIMMCL_03197 5.9e-274 I Pfam Lipase (class 3)
CFDIMMCL_03198 1.8e-34
CFDIMMCL_03200 9.4e-299 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
CFDIMMCL_03201 7.3e-220 rafB P LacY proton/sugar symporter
CFDIMMCL_03202 1e-184 scrR K transcriptional
CFDIMMCL_03203 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CFDIMMCL_03204 6.7e-164 yraN K Transcriptional regulator
CFDIMMCL_03205 4.5e-216 yraM S PrpF protein
CFDIMMCL_03206 3.3e-242 EGP Sugar (and other) transporter
CFDIMMCL_03207 5.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
CFDIMMCL_03208 2.3e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
CFDIMMCL_03209 3.9e-282 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
CFDIMMCL_03210 7.4e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
CFDIMMCL_03211 5e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFDIMMCL_03212 1.6e-79 M Ribonuclease
CFDIMMCL_03213 2.6e-143 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
CFDIMMCL_03214 1.2e-36 crh G Phosphocarrier protein Chr
CFDIMMCL_03215 3.1e-170 whiA K May be required for sporulation
CFDIMMCL_03216 1.3e-34 ybhK S Required for morphogenesis under gluconeogenic growth conditions
CFDIMMCL_03217 1.5e-114 ybhK S Required for morphogenesis under gluconeogenic growth conditions
CFDIMMCL_03218 1.1e-166 rapZ S Displays ATPase and GTPase activities
CFDIMMCL_03219 6.5e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
CFDIMMCL_03220 3.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CFDIMMCL_03221 2.7e-125 usp CBM50 M protein conserved in bacteria
CFDIMMCL_03222 2.9e-276 S COG0457 FOG TPR repeat
CFDIMMCL_03223 2.9e-193 sasA T Histidine kinase
CFDIMMCL_03224 5e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CFDIMMCL_03225 0.0 msbA2 3.6.3.44 V ABC transporter
CFDIMMCL_03226 3.3e-112 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
CFDIMMCL_03227 9.6e-138 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
CFDIMMCL_03228 3.4e-132 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CFDIMMCL_03229 6e-117 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CFDIMMCL_03230 3e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
CFDIMMCL_03231 7e-237 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CFDIMMCL_03232 2.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
CFDIMMCL_03233 3.6e-208 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CFDIMMCL_03234 1.8e-138 yvpB NU protein conserved in bacteria
CFDIMMCL_03235 5.4e-84 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
CFDIMMCL_03236 1.7e-114 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
CFDIMMCL_03237 1.2e-151 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CFDIMMCL_03238 1.5e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CFDIMMCL_03239 9.2e-228 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
CFDIMMCL_03240 1.2e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CFDIMMCL_03241 1.1e-133 yvoA K transcriptional
CFDIMMCL_03242 1.2e-105 yxaF K Transcriptional regulator
CFDIMMCL_03243 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
CFDIMMCL_03244 3.9e-41 yvlD S Membrane
CFDIMMCL_03245 9.6e-26 pspB KT PspC domain
CFDIMMCL_03246 3.2e-166 yvlB S Putative adhesin
CFDIMMCL_03247 6.1e-49 yvlA
CFDIMMCL_03248 3e-38 yvkN
CFDIMMCL_03249 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
CFDIMMCL_03250 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CFDIMMCL_03251 7.6e-33 csbA S protein conserved in bacteria
CFDIMMCL_03252 0.0 yvkC 2.7.9.2 GT Phosphotransferase
CFDIMMCL_03253 2.7e-45 yvkC 2.7.9.2 GT Phosphotransferase
CFDIMMCL_03254 2.4e-110 yvkB K Transcriptional regulator
CFDIMMCL_03255 3e-227 yvkA EGP Major facilitator Superfamily
CFDIMMCL_03256 4.3e-211 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFDIMMCL_03257 4.1e-56 swrA S Swarming motility protein
CFDIMMCL_03258 5e-257 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
CFDIMMCL_03259 8.8e-230 ywoF P Right handed beta helix region
CFDIMMCL_03260 1.7e-154 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
CFDIMMCL_03261 1e-122 ftsE D cell division ATP-binding protein FtsE
CFDIMMCL_03262 2.8e-36 cccB C COG2010 Cytochrome c, mono- and diheme variants
CFDIMMCL_03263 9.3e-150 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
CFDIMMCL_03264 1.4e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CFDIMMCL_03265 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CFDIMMCL_03266 3.7e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CFDIMMCL_03267 5.3e-11 fliT S bacterial-type flagellum organization
CFDIMMCL_03268 3e-66 fliS N flagellar protein FliS
CFDIMMCL_03269 4.3e-262 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CFDIMMCL_03270 3.9e-116 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CFDIMMCL_03271 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CFDIMMCL_03272 8.5e-75 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CFDIMMCL_03273 1.2e-81 yviE
CFDIMMCL_03274 6.1e-163 flgL N Belongs to the bacterial flagellin family
CFDIMMCL_03275 4.4e-275 flgK N flagellar hook-associated protein
CFDIMMCL_03276 8.9e-81 flgN NOU FlgN protein
CFDIMMCL_03277 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
CFDIMMCL_03278 1.4e-74 yvyF S flagellar protein
CFDIMMCL_03279 1.1e-78 comFC S Phosphoribosyl transferase domain
CFDIMMCL_03280 1.5e-43 comFB S Late competence development protein ComFB
CFDIMMCL_03281 8.1e-268 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CFDIMMCL_03282 1.4e-158 degV S protein conserved in bacteria
CFDIMMCL_03283 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CFDIMMCL_03284 1.7e-181 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
CFDIMMCL_03285 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
CFDIMMCL_03286 3e-173 yvhJ K Transcriptional regulator
CFDIMMCL_03287 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
CFDIMMCL_03288 1.2e-240 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
CFDIMMCL_03289 6.8e-144 tuaG GT2 M Glycosyltransferase like family 2
CFDIMMCL_03290 6.4e-117 tuaF M protein involved in exopolysaccharide biosynthesis
CFDIMMCL_03291 1.7e-260 tuaE M Teichuronic acid biosynthesis protein
CFDIMMCL_03292 7.8e-252 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CFDIMMCL_03293 3.9e-226 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
CFDIMMCL_03294 9.3e-259 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CFDIMMCL_03295 6.2e-117 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
CFDIMMCL_03296 5.4e-270 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
CFDIMMCL_03297 0.0 lytB 3.5.1.28 D Stage II sporulation protein
CFDIMMCL_03298 5.9e-49
CFDIMMCL_03299 1.7e-149 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
CFDIMMCL_03300 6.7e-212 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
CFDIMMCL_03301 2.8e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
CFDIMMCL_03302 4e-284 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
CFDIMMCL_03303 1.7e-151 tagG GM Transport permease protein
CFDIMMCL_03304 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CFDIMMCL_03305 3.3e-294 M Glycosyltransferase like family 2
CFDIMMCL_03306 3.8e-42 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
CFDIMMCL_03307 9.3e-19 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
CFDIMMCL_03308 1.5e-143 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
CFDIMMCL_03309 3.7e-221 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CFDIMMCL_03310 1.7e-245 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CFDIMMCL_03311 2.5e-191 pmi 5.3.1.8 G mannose-6-phosphate isomerase
CFDIMMCL_03312 9.3e-267 gerBA EG Spore germination protein
CFDIMMCL_03313 6.8e-201 gerBB E Spore germination protein
CFDIMMCL_03314 6.5e-215 gerAC S Spore germination protein
CFDIMMCL_03315 8.6e-270 GT2,GT4 J Glycosyl transferase family 2
CFDIMMCL_03316 3.7e-249 ywtG EGP Major facilitator Superfamily
CFDIMMCL_03317 3.8e-179 ywtF K Transcriptional regulator
CFDIMMCL_03318 4.5e-160 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
CFDIMMCL_03319 2.9e-38 yttA 2.7.13.3 S Pfam Transposase IS66
CFDIMMCL_03320 5.2e-242 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
CFDIMMCL_03321 1.3e-20 ywtC
CFDIMMCL_03322 1.2e-219 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
CFDIMMCL_03323 2.3e-70 pgsC S biosynthesis protein
CFDIMMCL_03324 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
CFDIMMCL_03325 1.7e-183 gerKA EG Spore germination protein
CFDIMMCL_03326 6.7e-193 gerKB E Spore germination protein
CFDIMMCL_03327 5.5e-206 gerKC S Spore germination B3/ GerAC like, C-terminal
CFDIMMCL_03328 1.8e-181 rbsR K transcriptional
CFDIMMCL_03329 6.1e-160 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFDIMMCL_03330 4.3e-65 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
CFDIMMCL_03331 3.4e-280 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
CFDIMMCL_03332 2.9e-155 rbsC G Belongs to the binding-protein-dependent transport system permease family
CFDIMMCL_03333 5.2e-162 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
CFDIMMCL_03334 1.4e-90 batE T Sh3 type 3 domain protein
CFDIMMCL_03335 2.2e-96 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
CFDIMMCL_03336 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
CFDIMMCL_03337 2.4e-309 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
CFDIMMCL_03338 9e-167 alsR K LysR substrate binding domain
CFDIMMCL_03339 1.2e-241 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CFDIMMCL_03340 1.2e-48 ywrJ
CFDIMMCL_03341 1.9e-32 ywrJ
CFDIMMCL_03342 4.4e-134 cotB
CFDIMMCL_03343 4.1e-214 cotH M Spore Coat
CFDIMMCL_03344 1.2e-09
CFDIMMCL_03345 2.5e-112 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFDIMMCL_03346 2e-307 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
CFDIMMCL_03347 1.1e-83 ywrC K Transcriptional regulator
CFDIMMCL_03348 8.3e-105 ywrB P Chromate transporter
CFDIMMCL_03349 2e-89 ywrA P COG2059 Chromate transport protein ChrA
CFDIMMCL_03350 1.5e-137 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
CFDIMMCL_03351 1.6e-93
CFDIMMCL_03352 4.6e-48 S SMI1 / KNR4 family (SUKH-1)
CFDIMMCL_03353 3.8e-104 S Domain of unknown function (DUF1851)
CFDIMMCL_03354 2.8e-79 S LXG domain of WXG superfamily
CFDIMMCL_03355 2.7e-85 L Molecular Function DNA binding, Biological Process DNA recombination
CFDIMMCL_03356 6.3e-93
CFDIMMCL_03357 2e-49
CFDIMMCL_03358 0.0 ywqJ S Pre-toxin TG
CFDIMMCL_03359 4.3e-37 ywqI S Family of unknown function (DUF5344)
CFDIMMCL_03360 8.5e-22 S Domain of unknown function (DUF5082)
CFDIMMCL_03362 9.9e-154 ywqG S Domain of unknown function (DUF1963)
CFDIMMCL_03363 9.5e-250 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CFDIMMCL_03364 1.7e-142 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
CFDIMMCL_03365 6.7e-122 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
CFDIMMCL_03366 5.2e-112 ywqC M biosynthesis protein
CFDIMMCL_03367 1.3e-14
CFDIMMCL_03368 2.2e-309 ywqB S SWIM zinc finger
CFDIMMCL_03369 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
CFDIMMCL_03370 2.5e-158 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
CFDIMMCL_03371 7.5e-138 glcR K DeoR C terminal sensor domain
CFDIMMCL_03372 7.5e-58 ssbB L Single-stranded DNA-binding protein
CFDIMMCL_03373 4e-62 ywpG
CFDIMMCL_03374 3.9e-69 ywpF S YwpF-like protein
CFDIMMCL_03375 1.4e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
CFDIMMCL_03376 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CFDIMMCL_03377 2e-45 S aspartate phosphatase
CFDIMMCL_03378 3.2e-141 S aspartate phosphatase
CFDIMMCL_03379 6.1e-146 flhP N flagellar basal body
CFDIMMCL_03380 3.2e-128 flhO N flagellar basal body
CFDIMMCL_03381 2.7e-180 mbl D Rod shape-determining protein
CFDIMMCL_03382 1.8e-44 spoIIID K Stage III sporulation protein D
CFDIMMCL_03383 8.5e-72 ywoH K transcriptional
CFDIMMCL_03384 3.8e-213 ywoG EGP Major facilitator Superfamily
CFDIMMCL_03385 1.9e-280 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
CFDIMMCL_03386 7.2e-245 ywoD EGP Major facilitator superfamily
CFDIMMCL_03387 5.7e-103 phzA Q Isochorismatase family
CFDIMMCL_03388 2.5e-228 amt P Ammonium transporter
CFDIMMCL_03389 2e-58 nrgB K Belongs to the P(II) protein family
CFDIMMCL_03390 2.2e-210 ftsW D Belongs to the SEDS family
CFDIMMCL_03391 3.2e-101 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
CFDIMMCL_03392 1.7e-72 ywnJ S VanZ like family
CFDIMMCL_03393 4.9e-122 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
CFDIMMCL_03394 4.9e-90 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
CFDIMMCL_03395 1.2e-10 ywnC S Family of unknown function (DUF5362)
CFDIMMCL_03396 1.3e-32 ywnF S Family of unknown function (DUF5392)
CFDIMMCL_03397 3.7e-257 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CFDIMMCL_03398 4.4e-54 ywnC S Family of unknown function (DUF5362)
CFDIMMCL_03399 3.1e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
CFDIMMCL_03400 2.1e-67 ywnA K Transcriptional regulator
CFDIMMCL_03401 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
CFDIMMCL_03402 3.8e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
CFDIMMCL_03403 1.1e-50 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
CFDIMMCL_03404 6.5e-11 csbD K CsbD-like
CFDIMMCL_03405 9.5e-83 ywmF S Peptidase M50
CFDIMMCL_03406 2.8e-93 S response regulator aspartate phosphatase
CFDIMMCL_03407 1.8e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CFDIMMCL_03408 2e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CFDIMMCL_03410 7.8e-123 ywmD S protein containing a von Willebrand factor type A (vWA) domain
CFDIMMCL_03411 1.2e-123 ywmC S protein containing a von Willebrand factor type A (vWA) domain
CFDIMMCL_03412 1.9e-189 spoIID D Stage II sporulation protein D
CFDIMMCL_03413 4.7e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CFDIMMCL_03414 4.1e-104 ywmB S TATA-box binding
CFDIMMCL_03415 1e-22 ywmB S TATA-box binding
CFDIMMCL_03416 1.3e-32 ywzB S membrane
CFDIMMCL_03417 1.2e-90 ywmA
CFDIMMCL_03418 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
CFDIMMCL_03419 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CFDIMMCL_03420 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CFDIMMCL_03421 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CFDIMMCL_03422 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CFDIMMCL_03423 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CFDIMMCL_03424 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CFDIMMCL_03425 5.4e-130 atpB C it plays a direct role in the translocation of protons across the membrane
CFDIMMCL_03426 2.1e-61 atpI S ATP synthase
CFDIMMCL_03427 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CFDIMMCL_03428 1.6e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CFDIMMCL_03429 8.3e-97 ywlG S Belongs to the UPF0340 family
CFDIMMCL_03430 1.1e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CFDIMMCL_03431 4.5e-92 mntP P Probably functions as a manganese efflux pump
CFDIMMCL_03432 3.2e-192 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
CFDIMMCL_03433 3.6e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
CFDIMMCL_03434 1.5e-121 spoIIR S stage II sporulation protein R
CFDIMMCL_03435 1e-60 ywlA S Uncharacterised protein family (UPF0715)
CFDIMMCL_03437 5.5e-158 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
CFDIMMCL_03438 1.9e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CFDIMMCL_03439 6.9e-68 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CFDIMMCL_03440 6.7e-96 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
CFDIMMCL_03441 3.6e-158 ywkB S Membrane transport protein
CFDIMMCL_03442 0.0 sfcA 1.1.1.38 C malic enzyme
CFDIMMCL_03443 1.4e-104 tdk 2.7.1.21 F thymidine kinase
CFDIMMCL_03444 1.1e-32 rpmE J Binds the 23S rRNA
CFDIMMCL_03445 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CFDIMMCL_03446 5.6e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
CFDIMMCL_03447 5.1e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CFDIMMCL_03448 6.4e-111 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CFDIMMCL_03449 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
CFDIMMCL_03450 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
CFDIMMCL_03451 1.7e-93 ywjG S Domain of unknown function (DUF2529)
CFDIMMCL_03452 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
CFDIMMCL_03453 2.2e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
CFDIMMCL_03454 0.0 fadF C COG0247 Fe-S oxidoreductase
CFDIMMCL_03455 1.3e-221 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
CFDIMMCL_03456 7.7e-185 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
CFDIMMCL_03457 2.4e-43 ywjC
CFDIMMCL_03458 0.0 ywjA V ABC transporter
CFDIMMCL_03459 9.6e-302 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CFDIMMCL_03460 2.8e-106 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
CFDIMMCL_03461 3.2e-83 narI 1.7.5.1 C nitrate reductase, gamma
CFDIMMCL_03462 3.5e-18 narI 1.7.5.1 C nitrate reductase, gamma
CFDIMMCL_03463 1.9e-98 narJ 1.7.5.1 C nitrate reductase
CFDIMMCL_03464 1.8e-294 narH 1.7.5.1 C Nitrate reductase, beta
CFDIMMCL_03465 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CFDIMMCL_03466 2e-85 arfM T cyclic nucleotide binding
CFDIMMCL_03467 5.1e-141 ywiC S YwiC-like protein
CFDIMMCL_03468 4.5e-129 fnr K helix_turn_helix, cAMP Regulatory protein
CFDIMMCL_03469 5.8e-214 narK P COG2223 Nitrate nitrite transporter
CFDIMMCL_03470 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
CFDIMMCL_03471 1.2e-73 ywiB S protein conserved in bacteria
CFDIMMCL_03473 1.4e-232 ywhL CO amine dehydrogenase activity
CFDIMMCL_03474 1.3e-222 ywhK CO amine dehydrogenase activity
CFDIMMCL_03475 2.4e-76 S aspartate phosphatase
CFDIMMCL_03477 2.6e-29 ydcG K sequence-specific DNA binding
CFDIMMCL_03478 5e-33
CFDIMMCL_03479 2e-28 S Domain of unknown function (DUF4177)
CFDIMMCL_03481 3.6e-77 CP Membrane
CFDIMMCL_03484 5.4e-169 speB 3.5.3.11 E Belongs to the arginase family
CFDIMMCL_03485 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CFDIMMCL_03486 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CFDIMMCL_03487 3.5e-84
CFDIMMCL_03488 1.5e-70 ywhD S YwhD family
CFDIMMCL_03489 1.1e-118 ywhC S Peptidase family M50
CFDIMMCL_03490 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
CFDIMMCL_03491 3.6e-70 ywhA K Transcriptional regulator
CFDIMMCL_03492 1.6e-247 yhdG_1 E C-terminus of AA_permease
CFDIMMCL_03493 9.2e-89 ywgA 2.1.1.72, 3.1.21.3
CFDIMMCL_03494 7.9e-257 ywfO S COG1078 HD superfamily phosphohydrolases
CFDIMMCL_03495 6.9e-36 ywzC S Belongs to the UPF0741 family
CFDIMMCL_03496 3e-110 rsfA_1
CFDIMMCL_03497 7.4e-52 padR K PadR family transcriptional regulator
CFDIMMCL_03498 8.1e-94 S membrane
CFDIMMCL_03499 9.1e-167 V ABC transporter, ATP-binding protein
CFDIMMCL_03500 3.5e-169 yhcI S ABC transporter (permease)
CFDIMMCL_03503 1.2e-179
CFDIMMCL_03505 2.7e-160 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
CFDIMMCL_03506 6e-163 cysL K Transcriptional regulator
CFDIMMCL_03507 7.9e-161 MA20_14895 S Conserved hypothetical protein 698
CFDIMMCL_03508 5.1e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
CFDIMMCL_03509 1.1e-146 ywfI C May function as heme-dependent peroxidase
CFDIMMCL_03510 7.5e-141 IQ Enoyl-(Acyl carrier protein) reductase
CFDIMMCL_03511 2.1e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
CFDIMMCL_03512 1.2e-208 bacE EGP Major facilitator Superfamily
CFDIMMCL_03513 2e-269 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
CFDIMMCL_03514 4.6e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CFDIMMCL_03515 1.5e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
CFDIMMCL_03516 3.9e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
CFDIMMCL_03517 2.6e-225 ywfA EGP Major facilitator Superfamily
CFDIMMCL_03518 4.3e-209 tcaB EGP Major facilitator Superfamily
CFDIMMCL_03519 2e-172 lysP E amino acid
CFDIMMCL_03520 0.0 rocB E arginine degradation protein
CFDIMMCL_03521 5.4e-297 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
CFDIMMCL_03522 1.5e-247 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
CFDIMMCL_03523 1.5e-164 T PhoQ Sensor
CFDIMMCL_03524 3.5e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CFDIMMCL_03525 4.9e-45 S Putative adhesin
CFDIMMCL_03526 3.9e-84
CFDIMMCL_03527 2.9e-120 S ABC-2 family transporter protein
CFDIMMCL_03528 6.7e-173 bcrA5 V ABC transporter, ATP-binding protein
CFDIMMCL_03529 2.7e-87 spsL 5.1.3.13 M Spore Coat
CFDIMMCL_03530 1.3e-162 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
CFDIMMCL_03531 9.3e-183 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CFDIMMCL_03532 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CFDIMMCL_03533 2.9e-190 spsG M Spore Coat
CFDIMMCL_03534 2.7e-137 spsF M Spore Coat
CFDIMMCL_03535 3.4e-216 spsE 2.5.1.56 M acid synthase
CFDIMMCL_03536 2.4e-161 spsD 2.3.1.210 K Spore Coat
CFDIMMCL_03537 5.1e-223 spsC E Belongs to the DegT DnrJ EryC1 family
CFDIMMCL_03538 1.2e-277 spsB M Capsule polysaccharide biosynthesis protein
CFDIMMCL_03539 2.6e-143 spsA M Spore Coat
CFDIMMCL_03540 1e-64 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
CFDIMMCL_03541 1.4e-46 ywdK S small membrane protein
CFDIMMCL_03542 5.2e-232 ywdJ F Xanthine uracil
CFDIMMCL_03543 7.3e-41 ywdI S Family of unknown function (DUF5327)
CFDIMMCL_03544 3.7e-133 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CFDIMMCL_03545 5.4e-155 ywdF GT2,GT4 S Glycosyltransferase like family 2
CFDIMMCL_03547 5.3e-89 ywdD
CFDIMMCL_03548 6.3e-57 pex K Transcriptional regulator PadR-like family
CFDIMMCL_03549 6e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
CFDIMMCL_03550 9.7e-20 ywdA
CFDIMMCL_03551 1.2e-290 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
CFDIMMCL_03552 3.6e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CFDIMMCL_03553 1.3e-151 sacT K transcriptional antiterminator
CFDIMMCL_03555 0.0 vpr O Belongs to the peptidase S8 family
CFDIMMCL_03556 3.9e-187 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFDIMMCL_03557 2.2e-54 L COG2963 Transposase and inactivated derivatives
CFDIMMCL_03558 3.2e-118 L Molecular Function DNA binding, Biological Process DNA recombination
CFDIMMCL_03559 2.7e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
CFDIMMCL_03560 9.8e-214 rodA D Belongs to the SEDS family
CFDIMMCL_03561 1e-82 ysnE K acetyltransferase
CFDIMMCL_03562 1e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
CFDIMMCL_03563 2e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
CFDIMMCL_03564 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
CFDIMMCL_03565 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CFDIMMCL_03566 8.3e-179 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
CFDIMMCL_03567 8.4e-27 ywzA S membrane
CFDIMMCL_03568 4.3e-302 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
CFDIMMCL_03569 5.7e-230 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CFDIMMCL_03570 1.9e-63 gtcA S GtrA-like protein
CFDIMMCL_03571 8.7e-113 ywcC K Bacterial regulatory proteins, tetR family
CFDIMMCL_03573 1.9e-129 H Methionine biosynthesis protein MetW
CFDIMMCL_03574 2.6e-134 S Streptomycin biosynthesis protein StrF
CFDIMMCL_03575 5.5e-112 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
CFDIMMCL_03576 1.1e-244 ywbN P Dyp-type peroxidase family protein
CFDIMMCL_03577 9.1e-116 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
CFDIMMCL_03578 6e-138 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CFDIMMCL_03579 8.2e-152 ywbI K Transcriptional regulator
CFDIMMCL_03580 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
CFDIMMCL_03581 1.5e-110 ywbG M effector of murein hydrolase
CFDIMMCL_03582 1.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
CFDIMMCL_03583 2.2e-142 mta K transcriptional
CFDIMMCL_03584 1.2e-171 yjfC O Predicted Zn-dependent protease (DUF2268)
CFDIMMCL_03585 5.5e-225 ywbD 2.1.1.191 J Methyltransferase
CFDIMMCL_03586 9e-68 ywbC 4.4.1.5 E glyoxalase
CFDIMMCL_03587 2.4e-245 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CFDIMMCL_03588 7e-269 epr 3.4.21.62 O Belongs to the peptidase S8 family
CFDIMMCL_03589 5.2e-164 gspA M General stress
CFDIMMCL_03590 7.8e-117 ywaC 2.7.6.5 S protein conserved in bacteria
CFDIMMCL_03591 1.3e-168 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
CFDIMMCL_03592 6.1e-12 S D-Ala-teichoic acid biosynthesis protein
CFDIMMCL_03593 4.2e-294 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFDIMMCL_03594 3.7e-229 dltB M membrane protein involved in D-alanine export
CFDIMMCL_03595 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFDIMMCL_03596 3.7e-229 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CFDIMMCL_03597 4e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
CFDIMMCL_03598 9.2e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
CFDIMMCL_03599 7.8e-52 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
CFDIMMCL_03600 2.6e-250 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CFDIMMCL_03601 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
CFDIMMCL_03602 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
CFDIMMCL_03603 1.1e-112 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
CFDIMMCL_03604 4.3e-173 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFDIMMCL_03605 6.1e-180 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFDIMMCL_03606 3e-167 cbrA3 P Periplasmic binding protein
CFDIMMCL_03607 3.7e-60 arsR K transcriptional
CFDIMMCL_03608 1.4e-229 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CFDIMMCL_03609 6.9e-50 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
CFDIMMCL_03610 1.4e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
CFDIMMCL_03611 3.7e-230 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CFDIMMCL_03612 7.1e-288 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CFDIMMCL_03613 4.2e-169 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
CFDIMMCL_03614 8.4e-192 manA 5.3.1.8 G mannose-6-phosphate isomerase
CFDIMMCL_03615 4.4e-213 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
CFDIMMCL_03616 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
CFDIMMCL_03617 6.5e-195 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
CFDIMMCL_03618 4.2e-253 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
CFDIMMCL_03619 7e-158 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CFDIMMCL_03620 2.2e-294 cydD V ATP-binding protein
CFDIMMCL_03621 0.0 cydD V ATP-binding
CFDIMMCL_03622 4.2e-189 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
CFDIMMCL_03623 1.4e-267 cydA 1.10.3.14 C oxidase, subunit
CFDIMMCL_03624 1.5e-215 cimH C COG3493 Na citrate symporter
CFDIMMCL_03625 7.1e-158 yxkH G Polysaccharide deacetylase
CFDIMMCL_03626 2.4e-206 msmK P Belongs to the ABC transporter superfamily
CFDIMMCL_03627 6.5e-170 lrp QT PucR C-terminal helix-turn-helix domain
CFDIMMCL_03628 6.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
CFDIMMCL_03629 3.8e-87 yxkC S Domain of unknown function (DUF4352)
CFDIMMCL_03630 2.1e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
CFDIMMCL_03631 6.5e-237 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
CFDIMMCL_03634 1.8e-86 yxjI S LURP-one-related
CFDIMMCL_03635 1.5e-219 yxjG 2.1.1.14 E Methionine synthase
CFDIMMCL_03636 5.6e-166 rlmA 2.1.1.187 Q Methyltransferase domain
CFDIMMCL_03637 3.5e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CFDIMMCL_03638 2.7e-75 T Domain of unknown function (DUF4163)
CFDIMMCL_03639 1.6e-51 yxiS
CFDIMMCL_03640 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
CFDIMMCL_03641 5.6e-223 citH C Citrate transporter
CFDIMMCL_03642 3.5e-143 exoK GH16 M licheninase activity
CFDIMMCL_03643 1.8e-150 licT K transcriptional antiterminator
CFDIMMCL_03644 2.9e-224 yxiO S COG2270 Permeases of the major facilitator superfamily
CFDIMMCL_03645 1.6e-263 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
CFDIMMCL_03648 2.9e-63 S SMI1-KNR4 cell-wall
CFDIMMCL_03649 9.1e-91 yxiI S Protein of unknown function (DUF2716)
CFDIMMCL_03651 3.1e-74 yxiG
CFDIMMCL_03652 7.1e-71 yxxG
CFDIMMCL_03655 3.7e-204 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
CFDIMMCL_03656 3.2e-148 yxxF EG EamA-like transporter family
CFDIMMCL_03657 9.8e-74 yxiE T Belongs to the universal stress protein A family
CFDIMMCL_03658 6.4e-281 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CFDIMMCL_03659 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CFDIMMCL_03660 0.0 L HKD family nuclease
CFDIMMCL_03661 6.5e-66 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
CFDIMMCL_03662 1.5e-282 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
CFDIMMCL_03663 7.7e-79 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
CFDIMMCL_03664 1e-287 hutH 4.3.1.3 E Histidine ammonia-lyase
CFDIMMCL_03665 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CFDIMMCL_03666 6.5e-240 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
CFDIMMCL_03667 3.1e-178 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
CFDIMMCL_03668 2e-253 lysP E amino acid
CFDIMMCL_03669 3.6e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
CFDIMMCL_03670 2.3e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CFDIMMCL_03671 9.4e-113 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CFDIMMCL_03672 2.3e-173 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
CFDIMMCL_03673 6.2e-151 yidA S hydrolases of the HAD superfamily
CFDIMMCL_03676 6.4e-13 yxeE
CFDIMMCL_03677 8.4e-23 yxeD
CFDIMMCL_03678 1.3e-14
CFDIMMCL_03679 7.5e-11
CFDIMMCL_03680 4.4e-180 fhuD P Periplasmic binding protein
CFDIMMCL_03681 2.2e-54 L COG2963 Transposase and inactivated derivatives
CFDIMMCL_03682 3.2e-118 L Molecular Function DNA binding, Biological Process DNA recombination
CFDIMMCL_03683 2.6e-58 yxeA S Protein of unknown function (DUF1093)
CFDIMMCL_03684 0.0 yxdM V ABC transporter (permease)
CFDIMMCL_03685 5.5e-141 yxdL V ABC transporter, ATP-binding protein
CFDIMMCL_03686 1e-176 T PhoQ Sensor
CFDIMMCL_03687 1.6e-97 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CFDIMMCL_03688 2.7e-14 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CFDIMMCL_03689 1.2e-255 T Histidine kinase
CFDIMMCL_03690 2.4e-138 T Transcriptional regulator
CFDIMMCL_03691 1.4e-164 bcrA V ABC transporter, ATP-binding protein
CFDIMMCL_03692 1e-131 S permease
CFDIMMCL_03693 9.3e-130 S ABC-2 family transporter protein
CFDIMMCL_03694 4.9e-162 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
CFDIMMCL_03695 1.3e-148 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
CFDIMMCL_03696 1.1e-166 iolH G Xylose isomerase-like TIM barrel
CFDIMMCL_03697 3.3e-197 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
CFDIMMCL_03698 2.4e-234 iolF EGP Major facilitator Superfamily
CFDIMMCL_03699 1e-178 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
CFDIMMCL_03700 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
CFDIMMCL_03701 6.8e-184 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
CFDIMMCL_03702 1.5e-157 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
CFDIMMCL_03703 1.2e-282 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CFDIMMCL_03704 3.1e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
CFDIMMCL_03705 4.9e-176 iolS C Aldo keto reductase
CFDIMMCL_03706 6.7e-246 csbC EGP Major facilitator Superfamily
CFDIMMCL_03707 0.0 htpG O Molecular chaperone. Has ATPase activity
CFDIMMCL_03708 5.7e-152 IQ Enoyl-(Acyl carrier protein) reductase
CFDIMMCL_03709 2.5e-104 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CFDIMMCL_03710 1.7e-202 desK 2.7.13.3 T Histidine kinase
CFDIMMCL_03711 3.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
CFDIMMCL_03712 4.3e-222 yxbF K Bacterial regulatory proteins, tetR family
CFDIMMCL_03713 3.9e-251 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
CFDIMMCL_03714 3.3e-143 S PQQ-like domain
CFDIMMCL_03715 4.1e-66 S Family of unknown function (DUF5391)
CFDIMMCL_03716 7.8e-51 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
CFDIMMCL_03717 6.7e-207 EGP Major facilitator Superfamily
CFDIMMCL_03718 5.3e-75 yxaI S membrane protein domain
CFDIMMCL_03719 5.1e-130 E Ring-cleavage extradiol dioxygenase
CFDIMMCL_03720 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
CFDIMMCL_03721 2.3e-287 ahpF O Alkyl hydroperoxide reductase
CFDIMMCL_03722 5.4e-231 XK27_00240 S Fic/DOC family
CFDIMMCL_03723 6.5e-246 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
CFDIMMCL_03724 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
CFDIMMCL_03725 3e-86 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
CFDIMMCL_03726 5.8e-160 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
CFDIMMCL_03727 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
CFDIMMCL_03728 2.3e-97 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
CFDIMMCL_03729 1.3e-193 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CFDIMMCL_03730 2.6e-180 S Fusaric acid resistance protein-like
CFDIMMCL_03734 9.4e-286 L ATPase involved in DNA repair
CFDIMMCL_03735 2.8e-08
CFDIMMCL_03736 4.6e-238 T Putative serine esterase (DUF676)
CFDIMMCL_03737 9.8e-190
CFDIMMCL_03738 8.9e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CFDIMMCL_03739 7.9e-08 S YyzF-like protein
CFDIMMCL_03741 3.5e-224 yycP
CFDIMMCL_03742 1.7e-134 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CFDIMMCL_03743 1.4e-186 C oxidoreductases (related to aryl-alcohol dehydrogenases)
CFDIMMCL_03744 1.5e-88 yycN 2.3.1.128 K Acetyltransferase
CFDIMMCL_03746 8.6e-204 S Histidine kinase
CFDIMMCL_03747 1.8e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
CFDIMMCL_03748 6.9e-259 rocE E amino acid
CFDIMMCL_03749 5.1e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
CFDIMMCL_03750 3.4e-261 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
CFDIMMCL_03751 5.3e-146 1.14.11.27 P peptidyl-arginine hydroxylation
CFDIMMCL_03752 7.9e-307 S ABC transporter
CFDIMMCL_03753 1.1e-140 S Major Facilitator Superfamily
CFDIMMCL_03754 4.7e-265
CFDIMMCL_03755 2.5e-194 2.7.7.73, 2.7.7.80 H ThiF family
CFDIMMCL_03756 1.8e-259 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
CFDIMMCL_03757 3.2e-11 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CFDIMMCL_03758 8.3e-221 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFDIMMCL_03759 1.8e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
CFDIMMCL_03760 8.9e-153 yycI S protein conserved in bacteria
CFDIMMCL_03761 2.5e-261 yycH S protein conserved in bacteria
CFDIMMCL_03762 0.0 vicK 2.7.13.3 T Histidine kinase
CFDIMMCL_03763 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CFDIMMCL_03768 1e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CFDIMMCL_03769 4.8e-75 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CFDIMMCL_03770 2.8e-252 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
CFDIMMCL_03771 1.6e-28 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
CFDIMMCL_03773 3.5e-17 yycC K YycC-like protein
CFDIMMCL_03774 2.9e-41 M 4-amino-4-deoxy-L-arabinose transferase activity
CFDIMMCL_03775 3e-248 M Glycosyltransferase Family 4
CFDIMMCL_03776 3.5e-207 S Ecdysteroid kinase
CFDIMMCL_03777 7.5e-238 S Carbamoyl-phosphate synthase L chain, ATP binding domain
CFDIMMCL_03778 5.4e-253 M Glycosyltransferase Family 4
CFDIMMCL_03779 9.8e-123 S GlcNAc-PI de-N-acetylase
CFDIMMCL_03780 1.8e-127 KLT COG0515 Serine threonine protein kinase
CFDIMMCL_03781 4.9e-73 rplI J binds to the 23S rRNA
CFDIMMCL_03782 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
CFDIMMCL_03783 2.9e-160 yybS S membrane
CFDIMMCL_03785 6e-85 cotF M Spore coat protein
CFDIMMCL_03786 2.8e-66 ydeP3 K Transcriptional regulator
CFDIMMCL_03787 1.7e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
CFDIMMCL_03788 1.4e-156 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
CFDIMMCL_03789 7e-275 sacB 2.4.1.10 GH68 M levansucrase activity
CFDIMMCL_03790 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
CFDIMMCL_03791 4.8e-117 K FCD domain
CFDIMMCL_03792 1.3e-77 dinB S PFAM DinB family protein
CFDIMMCL_03793 1.2e-163 G Major Facilitator Superfamily
CFDIMMCL_03794 1.7e-17 G Major Facilitator Superfamily
CFDIMMCL_03795 3.4e-163 yfiE K LysR substrate binding domain
CFDIMMCL_03796 1.1e-100 E LysE type translocator
CFDIMMCL_03797 3e-218 ynfM EGP Major facilitator Superfamily
CFDIMMCL_03798 3.3e-166 gltC K Transcriptional regulator
CFDIMMCL_03799 3.4e-56 ypaA S Protein of unknown function (DUF1304)
CFDIMMCL_03800 5.6e-115 drgA C nitroreductase
CFDIMMCL_03801 1.1e-69 ydgJ K Winged helix DNA-binding domain
CFDIMMCL_03802 3.8e-154 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
CFDIMMCL_03803 2.5e-77 yybA 2.3.1.57 K transcriptional
CFDIMMCL_03804 1.8e-77 yjcF S Acetyltransferase (GNAT) domain
CFDIMMCL_03805 2.3e-164 eaeH M Domain of Unknown Function (DUF1259)
CFDIMMCL_03806 9.4e-68 4.1.1.44 S Carboxymuconolactone decarboxylase family
CFDIMMCL_03807 4.5e-166 K Transcriptional regulator
CFDIMMCL_03808 3.6e-143 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
CFDIMMCL_03809 4.4e-100
CFDIMMCL_03810 1.5e-27 yyaL O Highly conserved protein containing a thioredoxin domain
CFDIMMCL_03811 4e-81
CFDIMMCL_03812 1.3e-69 ynaF
CFDIMMCL_03814 1e-96 KLT Protein tyrosine kinase
CFDIMMCL_03815 5.1e-145 KLT Protein tyrosine kinase
CFDIMMCL_03816 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
CFDIMMCL_03817 1.3e-165 yyaK S CAAX protease self-immunity
CFDIMMCL_03818 2.1e-249 ydjK G Sugar (and other) transporter
CFDIMMCL_03819 8.9e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CFDIMMCL_03820 4.3e-180 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
CFDIMMCL_03821 5.1e-147 xth 3.1.11.2 L exodeoxyribonuclease III
CFDIMMCL_03822 4.3e-103 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFDIMMCL_03823 4.9e-110 adaA 3.2.2.21 K Transcriptional regulator
CFDIMMCL_03824 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CFDIMMCL_03825 3.8e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CFDIMMCL_03826 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
CFDIMMCL_03827 1.8e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
CFDIMMCL_03828 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CFDIMMCL_03829 7.8e-34 yyzM S protein conserved in bacteria
CFDIMMCL_03830 2.4e-176 yyaD S Membrane
CFDIMMCL_03831 1.8e-87 4.2.1.103 K FR47-like protein
CFDIMMCL_03832 6.2e-111 yyaC S Sporulation protein YyaC
CFDIMMCL_03833 1.6e-149 spo0J K Belongs to the ParB family
CFDIMMCL_03834 9.2e-136 soj D COG1192 ATPases involved in chromosome partitioning
CFDIMMCL_03835 1.3e-151 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
CFDIMMCL_03836 1.3e-128 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
CFDIMMCL_03837 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
CFDIMMCL_03838 5.2e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CFDIMMCL_03839 4.5e-112 jag S single-stranded nucleic acid binding R3H
CFDIMMCL_03840 1.9e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CFDIMMCL_03841 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
CFDIMMCL_03842 4.7e-249 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CFDIMMCL_03843 7.2e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CFDIMMCL_03844 2.4e-33 yaaA S S4 domain
CFDIMMCL_03845 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CFDIMMCL_03846 8.1e-38 yaaB S Domain of unknown function (DUF370)
CFDIMMCL_03847 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CFDIMMCL_03848 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CFDIMMCL_03849 3.4e-39 S COG NOG14552 non supervised orthologous group
CFDIMMCL_03852 1.8e-184 yaaC S YaaC-like Protein
CFDIMMCL_03853 8e-274 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
CFDIMMCL_03854 1.2e-249 dacA 3.4.16.4 M Belongs to the peptidase S11 family
CFDIMMCL_03855 5.7e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CFDIMMCL_03856 2.5e-109 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CFDIMMCL_03857 1.6e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CFDIMMCL_03858 5e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
CFDIMMCL_03859 1.3e-09
CFDIMMCL_03860 4.8e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
CFDIMMCL_03861 1.1e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
CFDIMMCL_03862 8.9e-213 yaaH M Glycoside Hydrolase Family
CFDIMMCL_03863 2e-100 yaaI Q COG1335 Amidases related to nicotinamidase
CFDIMMCL_03864 3.5e-85 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
CFDIMMCL_03865 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CFDIMMCL_03866 5.9e-36 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CFDIMMCL_03867 2.3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CFDIMMCL_03868 3.6e-32 yaaL S Protein of unknown function (DUF2508)
CFDIMMCL_03869 1.9e-37 bofA S Sigma-K factor-processing regulatory protein BofA
CFDIMMCL_03870 3.4e-39 S COG NOG14552 non supervised orthologous group

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)