ORF_ID e_value Gene_name EC_number CAZy COGs Description
HPLIPDHJ_00001 3.9e-153 C Aldo keto reductase
HPLIPDHJ_00002 0.0 lmrA 3.6.3.44 V ABC transporter
HPLIPDHJ_00003 1.4e-69 K helix_turn_helix multiple antibiotic resistance protein
HPLIPDHJ_00004 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HPLIPDHJ_00005 3.7e-40 yphH S Cupin domain
HPLIPDHJ_00006 1.3e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HPLIPDHJ_00007 1.3e-31 L COG2826 Transposase and inactivated derivatives, IS30 family
HPLIPDHJ_00008 1e-25 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HPLIPDHJ_00009 5.2e-91 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
HPLIPDHJ_00010 2.2e-14 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HPLIPDHJ_00011 2.9e-172 tcsA S ABC transporter substrate-binding protein PnrA-like
HPLIPDHJ_00012 6.9e-220 xylG 3.6.3.17 S ABC transporter
HPLIPDHJ_00013 1.8e-164 yufP S Belongs to the binding-protein-dependent transport system permease family
HPLIPDHJ_00014 6.2e-150 yufQ S Belongs to the binding-protein-dependent transport system permease family
HPLIPDHJ_00015 3.8e-227 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HPLIPDHJ_00017 1.9e-162 XK27_00915 C Luciferase-like monooxygenase
HPLIPDHJ_00018 0.0 uvrA3 L excinuclease ABC, A subunit
HPLIPDHJ_00019 4e-137 S PFAM Archaeal ATPase
HPLIPDHJ_00020 9.4e-18 S PFAM Archaeal ATPase
HPLIPDHJ_00021 8.8e-10 S PFAM Archaeal ATPase
HPLIPDHJ_00022 3.7e-67 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HPLIPDHJ_00023 7.7e-08 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HPLIPDHJ_00024 1.6e-15 XK27_08875 O Peptidase family M54
HPLIPDHJ_00025 2.3e-136 H Nodulation protein S (NodS)
HPLIPDHJ_00026 1.5e-164 mntH P H( )-stimulated, divalent metal cation uptake system
HPLIPDHJ_00027 6.6e-14 mntH P H( )-stimulated, divalent metal cation uptake system
HPLIPDHJ_00028 5.6e-43 mntH P H( )-stimulated, divalent metal cation uptake system
HPLIPDHJ_00029 2.8e-54 yitW S Iron-sulfur cluster assembly protein
HPLIPDHJ_00030 3.8e-273 sufB O assembly protein SufB
HPLIPDHJ_00031 1.4e-78 nifU C SUF system FeS assembly protein, NifU family
HPLIPDHJ_00032 1.4e-223 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HPLIPDHJ_00033 1e-218 sufD O FeS assembly protein SufD
HPLIPDHJ_00034 5.1e-142 sufC O FeS assembly ATPase SufC
HPLIPDHJ_00035 6.2e-244 brnQ U Component of the transport system for branched-chain amino acids
HPLIPDHJ_00036 7.1e-61 S Putative adhesin
HPLIPDHJ_00037 8e-150 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HPLIPDHJ_00038 1.3e-87 S Peptidase propeptide and YPEB domain
HPLIPDHJ_00039 3.3e-234 T GHKL domain
HPLIPDHJ_00040 5.9e-126 T Transcriptional regulatory protein, C terminal
HPLIPDHJ_00041 4.4e-91 3.6.1.55 F NUDIX domain
HPLIPDHJ_00042 5.3e-107 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HPLIPDHJ_00044 8.4e-75 S reductase
HPLIPDHJ_00045 3.8e-109 S Protein of unknown function (DUF1211)
HPLIPDHJ_00046 2.7e-39 sprD D Domain of Unknown Function (DUF1542)
HPLIPDHJ_00047 8.3e-70 K LytTr DNA-binding domain
HPLIPDHJ_00048 7.2e-63 S Protein of unknown function (DUF3021)
HPLIPDHJ_00049 1e-128 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
HPLIPDHJ_00050 1.2e-277 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HPLIPDHJ_00051 4.5e-82 XK26_02160 S Pyridoxamine 5'-phosphate oxidase
HPLIPDHJ_00052 1.1e-81 K Transcriptional regulator
HPLIPDHJ_00053 1.4e-176 MA20_14895 S Conserved hypothetical protein 698
HPLIPDHJ_00054 7.2e-72
HPLIPDHJ_00056 4.5e-100 S LexA-binding, inner membrane-associated putative hydrolase
HPLIPDHJ_00057 1.4e-94 K LysR substrate binding domain
HPLIPDHJ_00058 3.2e-177 lacX 5.1.3.3 G Aldose 1-epimerase
HPLIPDHJ_00059 4e-251 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HPLIPDHJ_00060 2.2e-88 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HPLIPDHJ_00061 1.4e-170 xerC D Phage integrase, N-terminal SAM-like domain
HPLIPDHJ_00062 6.7e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HPLIPDHJ_00063 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HPLIPDHJ_00064 1.1e-153 dprA LU DNA protecting protein DprA
HPLIPDHJ_00065 5.4e-133 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HPLIPDHJ_00066 1.2e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HPLIPDHJ_00067 2.6e-261 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HPLIPDHJ_00068 6e-35 yozE S Belongs to the UPF0346 family
HPLIPDHJ_00069 1.2e-147 DegV S Uncharacterised protein, DegV family COG1307
HPLIPDHJ_00070 5.8e-115 hlyIII S protein, hemolysin III
HPLIPDHJ_00071 2.3e-226 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HPLIPDHJ_00072 1.9e-161 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HPLIPDHJ_00073 8.9e-82
HPLIPDHJ_00074 4.2e-151 mrr L restriction endonuclease
HPLIPDHJ_00075 2.7e-17 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HPLIPDHJ_00076 2.3e-109 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HPLIPDHJ_00077 2.2e-36 hsdS-1 3.1.21.3 L Type I restriction modification DNA specificity domain
HPLIPDHJ_00078 4e-154 L Belongs to the 'phage' integrase family
HPLIPDHJ_00079 5.6e-71 3.1.21.3 V Type I restriction modification DNA specificity domain
HPLIPDHJ_00080 2.6e-217 hsdM 2.1.1.72 V type I restriction-modification system
HPLIPDHJ_00081 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HPLIPDHJ_00082 4.9e-80
HPLIPDHJ_00083 0.0 KL domain protein
HPLIPDHJ_00084 1e-229 S Tetratricopeptide repeat protein
HPLIPDHJ_00085 6.7e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HPLIPDHJ_00086 5.3e-245 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HPLIPDHJ_00087 5.6e-217 rpsA 1.17.7.4 J Ribosomal protein S1
HPLIPDHJ_00088 1.1e-116 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HPLIPDHJ_00089 2.3e-94 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HPLIPDHJ_00090 1.7e-62 M Lysin motif
HPLIPDHJ_00091 2.6e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HPLIPDHJ_00092 1.7e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HPLIPDHJ_00093 9.1e-133 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HPLIPDHJ_00094 5.3e-62 ribT K acetyltransferase
HPLIPDHJ_00095 1.1e-164 xerD D recombinase XerD
HPLIPDHJ_00096 4.8e-165 cvfB S S1 domain
HPLIPDHJ_00097 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HPLIPDHJ_00098 1.8e-181 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HPLIPDHJ_00099 0.0 dnaE 2.7.7.7 L DNA polymerase
HPLIPDHJ_00100 6.9e-27 S Protein of unknown function (DUF2929)
HPLIPDHJ_00101 7.9e-304 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HPLIPDHJ_00102 1e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HPLIPDHJ_00103 7.5e-47 yrvD S Lipopolysaccharide assembly protein A domain
HPLIPDHJ_00104 1.8e-142 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HPLIPDHJ_00105 3e-178 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HPLIPDHJ_00106 0.0 oatA I Acyltransferase
HPLIPDHJ_00107 2.7e-241 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HPLIPDHJ_00108 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HPLIPDHJ_00109 2.7e-174 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
HPLIPDHJ_00110 1e-89 dedA 3.1.3.1 S SNARE associated Golgi protein
HPLIPDHJ_00111 1.7e-148 xerD L Phage integrase, N-terminal SAM-like domain
HPLIPDHJ_00112 5.5e-245 yagE E amino acid
HPLIPDHJ_00114 8.9e-92 S Rib/alpha-like repeat
HPLIPDHJ_00115 1.9e-65 S Domain of unknown function DUF1828
HPLIPDHJ_00116 4.4e-65
HPLIPDHJ_00117 1.1e-36
HPLIPDHJ_00118 2.9e-24 mutT 3.6.1.55 F NUDIX domain
HPLIPDHJ_00119 1.2e-35 mutT 3.6.1.55 F NUDIX domain
HPLIPDHJ_00120 3.3e-62
HPLIPDHJ_00122 2.7e-142 htpX O Peptidase family M48
HPLIPDHJ_00123 2.3e-139 L Reverse transcriptase (RNA-dependent DNA polymerase)
HPLIPDHJ_00125 3.8e-187 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HPLIPDHJ_00126 1.6e-93 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HPLIPDHJ_00127 1.2e-21 S KAP family P-loop domain
HPLIPDHJ_00128 3.4e-175 S Acyltransferase family
HPLIPDHJ_00129 1.4e-262 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
HPLIPDHJ_00130 4.9e-173 S Core-2/I-Branching enzyme
HPLIPDHJ_00131 1.3e-212 glf 5.4.99.9 M UDP-galactopyranose mutase
HPLIPDHJ_00132 7.7e-71 S Psort location CytoplasmicMembrane, score 9.99
HPLIPDHJ_00133 1.3e-173 glfT1 1.1.1.133 S Glycosyltransferase like family 2
HPLIPDHJ_00134 1.4e-203 M Glycosyl transferases group 1
HPLIPDHJ_00135 3e-140 M Glycosyl transferases group 1
HPLIPDHJ_00136 1.6e-146 M Glycosyl transferases group 1
HPLIPDHJ_00137 8.6e-124 waaB GT4 M Glycosyl transferases group 1
HPLIPDHJ_00138 2.9e-142 cps1D M Domain of unknown function (DUF4422)
HPLIPDHJ_00139 1.5e-118 rfbP M Bacterial sugar transferase
HPLIPDHJ_00140 4.4e-138 ywqE 3.1.3.48 GM PHP domain protein
HPLIPDHJ_00141 2e-122 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HPLIPDHJ_00142 1.1e-142 epsB M biosynthesis protein
HPLIPDHJ_00143 1.5e-151 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HPLIPDHJ_00144 3.5e-35 K DNA-templated transcription, initiation
HPLIPDHJ_00145 6.8e-116
HPLIPDHJ_00146 2.2e-65 frnE Q DSBA-like thioredoxin domain
HPLIPDHJ_00147 2e-217
HPLIPDHJ_00148 1.9e-76 S Domain of unknown function (DUF4767)
HPLIPDHJ_00149 1.9e-56 frnE Q DSBA-like thioredoxin domain
HPLIPDHJ_00150 4e-28 frnE Q DSBA-like thioredoxin domain
HPLIPDHJ_00152 7.1e-76
HPLIPDHJ_00153 1.6e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HPLIPDHJ_00154 2.6e-103 engB D Necessary for normal cell division and for the maintenance of normal septation
HPLIPDHJ_00155 2.5e-231 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HPLIPDHJ_00156 7.5e-202 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HPLIPDHJ_00157 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HPLIPDHJ_00158 1.5e-155
HPLIPDHJ_00159 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HPLIPDHJ_00160 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HPLIPDHJ_00161 7.5e-34 rpsT J Binds directly to 16S ribosomal RNA
HPLIPDHJ_00162 1.1e-173 holA 2.7.7.7 L DNA polymerase III delta subunit
HPLIPDHJ_00163 0.0 comEC S Competence protein ComEC
HPLIPDHJ_00164 3.3e-81 comEA L Competence protein ComEA
HPLIPDHJ_00165 2e-183 ylbL T Belongs to the peptidase S16 family
HPLIPDHJ_00166 2.4e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HPLIPDHJ_00167 2.5e-95 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HPLIPDHJ_00168 3.7e-49 ylbG S UPF0298 protein
HPLIPDHJ_00169 2.9e-210 ftsW D Belongs to the SEDS family
HPLIPDHJ_00170 0.0 typA T GTP-binding protein TypA
HPLIPDHJ_00171 5.2e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HPLIPDHJ_00172 2.3e-34 ykzG S Belongs to the UPF0356 family
HPLIPDHJ_00173 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HPLIPDHJ_00174 1.5e-161 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HPLIPDHJ_00175 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HPLIPDHJ_00176 4.8e-114 S Repeat protein
HPLIPDHJ_00177 4.4e-123 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HPLIPDHJ_00178 7.4e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HPLIPDHJ_00179 1.4e-56 XK27_04120 S Putative amino acid metabolism
HPLIPDHJ_00180 2.6e-211 iscS 2.8.1.7 E Aminotransferase class V
HPLIPDHJ_00181 3.5e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HPLIPDHJ_00182 1e-31
HPLIPDHJ_00183 4.8e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HPLIPDHJ_00184 2.3e-33 cspA K 'Cold-shock' DNA-binding domain
HPLIPDHJ_00185 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HPLIPDHJ_00186 1.8e-83 gpsB D DivIVA domain protein
HPLIPDHJ_00187 1.7e-145 ylmH S S4 domain protein
HPLIPDHJ_00188 1.3e-26 yggT S YGGT family
HPLIPDHJ_00189 8.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HPLIPDHJ_00190 9.9e-242 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HPLIPDHJ_00191 2.3e-238 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HPLIPDHJ_00192 5.8e-152 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HPLIPDHJ_00193 1.8e-209 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HPLIPDHJ_00194 4e-259 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HPLIPDHJ_00195 5.4e-178 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HPLIPDHJ_00196 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HPLIPDHJ_00197 2.4e-54 ftsL D Cell division protein FtsL
HPLIPDHJ_00198 3.2e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HPLIPDHJ_00199 1.6e-76 mraZ K Belongs to the MraZ family
HPLIPDHJ_00200 1e-51 S Protein of unknown function (DUF3397)
HPLIPDHJ_00201 3.6e-13 S Protein of unknown function (DUF4044)
HPLIPDHJ_00202 1.6e-94 mreD
HPLIPDHJ_00203 1.8e-140 mreC M Involved in formation and maintenance of cell shape
HPLIPDHJ_00204 7.8e-164 mreB D cell shape determining protein MreB
HPLIPDHJ_00205 4.4e-109 radC L DNA repair protein
HPLIPDHJ_00206 1.7e-122 S Haloacid dehalogenase-like hydrolase
HPLIPDHJ_00207 6.1e-230 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HPLIPDHJ_00208 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HPLIPDHJ_00209 0.0 3.6.3.8 P P-type ATPase
HPLIPDHJ_00210 3.5e-118 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HPLIPDHJ_00211 1.4e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HPLIPDHJ_00212 1.5e-214 iscS2 2.8.1.7 E Aminotransferase class V
HPLIPDHJ_00213 2.1e-289 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HPLIPDHJ_00215 1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HPLIPDHJ_00216 8.6e-81 yueI S Protein of unknown function (DUF1694)
HPLIPDHJ_00217 1.2e-233 rarA L recombination factor protein RarA
HPLIPDHJ_00219 1.5e-80 usp6 T universal stress protein
HPLIPDHJ_00220 1.2e-222 rodA D Belongs to the SEDS family
HPLIPDHJ_00221 6.6e-34 S Protein of unknown function (DUF2969)
HPLIPDHJ_00222 2.6e-51 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HPLIPDHJ_00223 6.8e-13 S DNA-directed RNA polymerase subunit beta
HPLIPDHJ_00224 1.7e-179 mbl D Cell shape determining protein MreB Mrl
HPLIPDHJ_00225 2e-30 ywzB S Protein of unknown function (DUF1146)
HPLIPDHJ_00226 1.2e-71 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HPLIPDHJ_00227 4.5e-245 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HPLIPDHJ_00228 1.2e-169 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HPLIPDHJ_00229 6.7e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HPLIPDHJ_00230 3.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HPLIPDHJ_00231 3.1e-52 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HPLIPDHJ_00232 4.7e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HPLIPDHJ_00233 5e-128 atpB C it plays a direct role in the translocation of protons across the membrane
HPLIPDHJ_00234 2.6e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HPLIPDHJ_00235 7.5e-183 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HPLIPDHJ_00236 6.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HPLIPDHJ_00237 1e-196 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HPLIPDHJ_00238 6e-111 tdk 2.7.1.21 F thymidine kinase
HPLIPDHJ_00239 9.3e-261 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
HPLIPDHJ_00240 1.1e-204 L Transposase DDE domain
HPLIPDHJ_00242 1.1e-54 D Cellulose biosynthesis protein BcsQ
HPLIPDHJ_00243 1e-104 xerC L Phage integrase, N-terminal SAM-like domain
HPLIPDHJ_00244 1.7e-280 phoR 2.7.13.3 T Histidine kinase
HPLIPDHJ_00245 3.4e-118 T Transcriptional regulatory protein, C terminal
HPLIPDHJ_00246 4.3e-107 phoU P Plays a role in the regulation of phosphate uptake
HPLIPDHJ_00247 3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HPLIPDHJ_00248 1.3e-151 pstA P Phosphate transport system permease protein PstA
HPLIPDHJ_00249 5.3e-135 pstC P probably responsible for the translocation of the substrate across the membrane
HPLIPDHJ_00250 5e-146 pstS P Phosphate
HPLIPDHJ_00251 4.9e-27 xerC L Phage integrase, N-terminal SAM-like domain
HPLIPDHJ_00253 3.4e-183 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HPLIPDHJ_00254 3.7e-124 manY G PTS system
HPLIPDHJ_00255 5.8e-169 manN G system, mannose fructose sorbose family IID component
HPLIPDHJ_00256 1.7e-63 manO S Domain of unknown function (DUF956)
HPLIPDHJ_00257 2.4e-251 yifK E Amino acid permease
HPLIPDHJ_00258 2.3e-230 yifK E Amino acid permease
HPLIPDHJ_00259 5.8e-135 puuD S peptidase C26
HPLIPDHJ_00260 6.5e-233 steT_1 E amino acid
HPLIPDHJ_00261 1.9e-189 asnA 6.3.1.1 F aspartate--ammonia ligase
HPLIPDHJ_00262 2.8e-160 EG EamA-like transporter family
HPLIPDHJ_00263 7.1e-256 yfnA E Amino Acid
HPLIPDHJ_00264 2.3e-130 cobQ S glutamine amidotransferase
HPLIPDHJ_00265 2.1e-146 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HPLIPDHJ_00266 1.5e-141 ptp2 3.1.3.48 T Tyrosine phosphatase family
HPLIPDHJ_00267 1.4e-184 scrR K Transcriptional regulator, LacI family
HPLIPDHJ_00268 5.1e-297 scrB 3.2.1.26 GH32 G invertase
HPLIPDHJ_00269 0.0 scrA 2.7.1.199, 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
HPLIPDHJ_00270 2.5e-89 ymdB S Macro domain protein
HPLIPDHJ_00271 1.9e-292 V ABC transporter transmembrane region
HPLIPDHJ_00272 2.4e-124 puuD S peptidase C26
HPLIPDHJ_00273 2.7e-94 mdtG EGP Major facilitator Superfamily
HPLIPDHJ_00274 4.8e-16 mdtG EGP Major Facilitator Superfamily
HPLIPDHJ_00275 2.4e-31 mdtG EGP Major Facilitator Superfamily
HPLIPDHJ_00276 1.8e-153
HPLIPDHJ_00277 1.6e-70 aroD 1.1.1.25, 4.2.1.10 E 3-dehydroquinate dehydratase activity
HPLIPDHJ_00278 1.8e-152 2.7.7.12 C Domain of unknown function (DUF4931)
HPLIPDHJ_00279 6.9e-153 ybbH_2 K Helix-turn-helix domain, rpiR family
HPLIPDHJ_00280 7.9e-13 3.4.16.4, 3.5.2.6 V Beta-lactamase enzyme family
HPLIPDHJ_00281 2.9e-109 3.4.16.4, 3.5.2.6 V Beta-lactamase enzyme family
HPLIPDHJ_00282 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
HPLIPDHJ_00283 1.7e-157 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HPLIPDHJ_00284 1.9e-124
HPLIPDHJ_00285 2.7e-50
HPLIPDHJ_00286 1.6e-137 S Belongs to the UPF0246 family
HPLIPDHJ_00287 6.5e-139 aroD S Alpha/beta hydrolase family
HPLIPDHJ_00288 5.7e-112 G Phosphoglycerate mutase family
HPLIPDHJ_00289 2.1e-108 G phosphoglycerate mutase
HPLIPDHJ_00290 6.9e-87 ygfC K Bacterial regulatory proteins, tetR family
HPLIPDHJ_00291 3.7e-180 hrtB V ABC transporter permease
HPLIPDHJ_00292 1.5e-118 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HPLIPDHJ_00293 3.5e-129 K CAT RNA binding domain
HPLIPDHJ_00294 2.4e-241 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HPLIPDHJ_00295 7.7e-266 pipD E Dipeptidase
HPLIPDHJ_00296 1e-37
HPLIPDHJ_00297 2.1e-106 K WHG domain
HPLIPDHJ_00298 3.9e-93 nqr 1.5.1.36 S reductase
HPLIPDHJ_00299 8.3e-99 azr 1.5.1.36 S NADPH-dependent FMN reductase
HPLIPDHJ_00300 1.9e-200 4.2.1.126 S Bacterial protein of unknown function (DUF871)
HPLIPDHJ_00301 9.1e-147 3.1.3.48 T Tyrosine phosphatase family
HPLIPDHJ_00302 2.3e-178 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HPLIPDHJ_00303 6.4e-96 cvpA S Colicin V production protein
HPLIPDHJ_00304 1.5e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HPLIPDHJ_00305 1.5e-142 noc K Belongs to the ParB family
HPLIPDHJ_00306 9.7e-138 soj D Sporulation initiation inhibitor
HPLIPDHJ_00307 2.2e-154 spo0J K Belongs to the ParB family
HPLIPDHJ_00308 2.9e-43 yyzM S Bacterial protein of unknown function (DUF951)
HPLIPDHJ_00309 4.4e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HPLIPDHJ_00310 4.3e-147 XK27_01040 S Protein of unknown function (DUF1129)
HPLIPDHJ_00311 1.3e-296 V ABC transporter, ATP-binding protein
HPLIPDHJ_00312 0.0 V ABC transporter
HPLIPDHJ_00313 7.4e-121 K response regulator
HPLIPDHJ_00314 1.2e-200 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
HPLIPDHJ_00315 1.7e-306 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HPLIPDHJ_00316 1.2e-143 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HPLIPDHJ_00317 4.4e-166 natA S ABC transporter, ATP-binding protein
HPLIPDHJ_00318 6.8e-218 natB CP ABC-2 family transporter protein
HPLIPDHJ_00319 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HPLIPDHJ_00320 1.2e-135 fruR K DeoR C terminal sensor domain
HPLIPDHJ_00321 2e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HPLIPDHJ_00322 0.0 fruA 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
HPLIPDHJ_00323 1.4e-35 S YSIRK type signal peptide
HPLIPDHJ_00324 4.2e-225 sdrF M domain protein
HPLIPDHJ_00325 3.4e-138 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
HPLIPDHJ_00326 2.1e-42 K helix_turn_helix, Arsenical Resistance Operon Repressor
HPLIPDHJ_00327 2.5e-153 psaA P Belongs to the bacterial solute-binding protein 9 family
HPLIPDHJ_00328 3.1e-116 fhuC P ABC transporter
HPLIPDHJ_00329 2.5e-133 znuB U ABC 3 transport family
HPLIPDHJ_00330 1.6e-256 lctP C L-lactate permease
HPLIPDHJ_00331 1.1e-183 S AAA domain
HPLIPDHJ_00332 4.5e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HPLIPDHJ_00333 9.9e-12
HPLIPDHJ_00334 5.2e-35
HPLIPDHJ_00335 5e-154 czcD P cation diffusion facilitator family transporter
HPLIPDHJ_00336 7e-53 K Transcriptional regulator, ArsR family
HPLIPDHJ_00337 1.6e-128 pgm3 G Belongs to the phosphoglycerate mutase family
HPLIPDHJ_00338 9.4e-109 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HPLIPDHJ_00339 1.4e-148 1.6.5.2 GM NmrA-like family
HPLIPDHJ_00340 1.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HPLIPDHJ_00341 5e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HPLIPDHJ_00342 1.9e-149 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HPLIPDHJ_00343 1.8e-139 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HPLIPDHJ_00344 1.1e-206 L Putative transposase DNA-binding domain
HPLIPDHJ_00345 2.5e-158 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HPLIPDHJ_00346 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HPLIPDHJ_00347 7.4e-62 rplQ J Ribosomal protein L17
HPLIPDHJ_00348 9.6e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPLIPDHJ_00349 2.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HPLIPDHJ_00350 1.2e-55 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HPLIPDHJ_00351 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HPLIPDHJ_00352 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HPLIPDHJ_00353 4.5e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HPLIPDHJ_00354 4.5e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HPLIPDHJ_00355 1.3e-70 rplO J Binds to the 23S rRNA
HPLIPDHJ_00356 1.4e-23 rpmD J Ribosomal protein L30
HPLIPDHJ_00357 1.9e-76 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HPLIPDHJ_00358 1.5e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HPLIPDHJ_00359 8.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HPLIPDHJ_00360 2.1e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HPLIPDHJ_00361 2.3e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HPLIPDHJ_00362 7.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HPLIPDHJ_00363 1.1e-34 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HPLIPDHJ_00364 5.6e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HPLIPDHJ_00365 7.7e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HPLIPDHJ_00366 2.2e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HPLIPDHJ_00367 6.6e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HPLIPDHJ_00368 1e-119 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HPLIPDHJ_00369 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HPLIPDHJ_00370 5e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HPLIPDHJ_00371 1.6e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HPLIPDHJ_00372 1.7e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HPLIPDHJ_00373 1e-105 rplD J Forms part of the polypeptide exit tunnel
HPLIPDHJ_00374 1.7e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HPLIPDHJ_00375 5.8e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HPLIPDHJ_00376 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HPLIPDHJ_00377 1e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HPLIPDHJ_00378 3.5e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HPLIPDHJ_00379 2.3e-95 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HPLIPDHJ_00380 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPLIPDHJ_00381 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPLIPDHJ_00382 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HPLIPDHJ_00384 1.6e-08
HPLIPDHJ_00385 6.8e-300 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HPLIPDHJ_00386 3.8e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HPLIPDHJ_00387 5.4e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HPLIPDHJ_00388 0.0 S membrane
HPLIPDHJ_00389 0.0 S membrane
HPLIPDHJ_00390 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HPLIPDHJ_00391 1.8e-240 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HPLIPDHJ_00392 9.3e-59 yabR J S1 RNA binding domain
HPLIPDHJ_00393 4e-60 divIC D Septum formation initiator
HPLIPDHJ_00394 2e-33 yabO J S4 domain protein
HPLIPDHJ_00395 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HPLIPDHJ_00396 2.5e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HPLIPDHJ_00397 4.7e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HPLIPDHJ_00398 3.5e-123 S (CBS) domain
HPLIPDHJ_00399 1.3e-212 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HPLIPDHJ_00400 2.1e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HPLIPDHJ_00401 6.5e-268 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HPLIPDHJ_00402 2.1e-260 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HPLIPDHJ_00403 2.8e-72 L COG3547 Transposase and inactivated derivatives
HPLIPDHJ_00404 1.8e-58 K Transcriptional regulator
HPLIPDHJ_00405 1.7e-149 yrvN L AAA C-terminal domain
HPLIPDHJ_00406 8.7e-14 akr5f 1.1.1.346 S reductase
HPLIPDHJ_00407 2.2e-108 lacA 2.3.1.79 S Transferase hexapeptide repeat
HPLIPDHJ_00408 8.3e-114 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HPLIPDHJ_00409 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HPLIPDHJ_00410 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HPLIPDHJ_00411 2.3e-24 K Transcriptional regulator
HPLIPDHJ_00412 8.9e-43 K Transcriptional regulator
HPLIPDHJ_00413 2.8e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
HPLIPDHJ_00414 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HPLIPDHJ_00415 1.5e-109 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HPLIPDHJ_00416 4.4e-121 yoaK S Protein of unknown function (DUF1275)
HPLIPDHJ_00417 2.3e-201 xerS L Belongs to the 'phage' integrase family
HPLIPDHJ_00418 3.9e-151 K Transcriptional regulator
HPLIPDHJ_00419 2.5e-150
HPLIPDHJ_00420 6.5e-162 degV S EDD domain protein, DegV family
HPLIPDHJ_00421 1.4e-63
HPLIPDHJ_00422 0.0 FbpA K Fibronectin-binding protein
HPLIPDHJ_00423 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
HPLIPDHJ_00424 2.5e-192 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HPLIPDHJ_00425 7.9e-171 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HPLIPDHJ_00426 3.7e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HPLIPDHJ_00427 7.9e-310 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HPLIPDHJ_00428 1.6e-55
HPLIPDHJ_00429 4.2e-172 degV S DegV family
HPLIPDHJ_00430 9.5e-40 I transferase activity, transferring acyl groups other than amino-acyl groups
HPLIPDHJ_00431 3.2e-53 I transferase activity, transferring acyl groups other than amino-acyl groups
HPLIPDHJ_00432 6.3e-240 cpdA S Calcineurin-like phosphoesterase
HPLIPDHJ_00433 6e-213 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HPLIPDHJ_00434 1.4e-69 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HPLIPDHJ_00435 6.9e-101 ypsA S Belongs to the UPF0398 family
HPLIPDHJ_00436 1.3e-113 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HPLIPDHJ_00437 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HPLIPDHJ_00438 3.6e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HPLIPDHJ_00439 1.5e-112 dnaD L DnaD domain protein
HPLIPDHJ_00440 1.9e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HPLIPDHJ_00441 1.7e-87 ypmB S Protein conserved in bacteria
HPLIPDHJ_00442 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HPLIPDHJ_00443 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HPLIPDHJ_00444 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HPLIPDHJ_00445 1e-165 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
HPLIPDHJ_00446 1.5e-172 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HPLIPDHJ_00447 4.3e-200 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HPLIPDHJ_00448 6.3e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HPLIPDHJ_00449 3.3e-198 V ABC-type multidrug transport system, ATPase and permease components
HPLIPDHJ_00450 2.7e-144 G Transmembrane secretion effector
HPLIPDHJ_00451 4.1e-48 G Transmembrane secretion effector
HPLIPDHJ_00452 9.8e-149 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
HPLIPDHJ_00453 2.7e-160 rbsU U ribose uptake protein RbsU
HPLIPDHJ_00454 5.6e-65 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HPLIPDHJ_00455 3.2e-62 yugI 5.3.1.9 J general stress protein
HPLIPDHJ_00456 3.1e-178 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
HPLIPDHJ_00457 2.7e-117 dedA S SNARE-like domain protein
HPLIPDHJ_00458 7.3e-104 S Protein of unknown function (DUF1461)
HPLIPDHJ_00459 9.8e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HPLIPDHJ_00460 2.4e-95 yutD S Protein of unknown function (DUF1027)
HPLIPDHJ_00461 4.7e-268 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HPLIPDHJ_00462 1.3e-54
HPLIPDHJ_00463 6.4e-265 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HPLIPDHJ_00464 2.2e-273 pepV 3.5.1.18 E dipeptidase PepV
HPLIPDHJ_00465 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M Penicillin binding protein transpeptidase domain
HPLIPDHJ_00466 2.2e-174 ccpA K catabolite control protein A
HPLIPDHJ_00467 3.6e-210 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HPLIPDHJ_00468 9.6e-50
HPLIPDHJ_00469 1.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HPLIPDHJ_00470 3e-138 ykuT M mechanosensitive ion channel
HPLIPDHJ_00471 5.5e-217 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HPLIPDHJ_00472 1.7e-116 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HPLIPDHJ_00473 1.1e-144 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HPLIPDHJ_00474 9.3e-68 yslB S Protein of unknown function (DUF2507)
HPLIPDHJ_00475 1.1e-52 trxA O Belongs to the thioredoxin family
HPLIPDHJ_00476 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HPLIPDHJ_00477 8.2e-91 cvpA S Colicin V production protein
HPLIPDHJ_00478 4.2e-39 yrzB S Belongs to the UPF0473 family
HPLIPDHJ_00479 1.5e-71 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HPLIPDHJ_00480 2.6e-42 yrzL S Belongs to the UPF0297 family
HPLIPDHJ_00481 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HPLIPDHJ_00482 2.9e-225 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HPLIPDHJ_00483 4.3e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HPLIPDHJ_00484 1.4e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HPLIPDHJ_00485 1.7e-281 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HPLIPDHJ_00486 2.5e-37 yajC U Preprotein translocase
HPLIPDHJ_00487 4.3e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HPLIPDHJ_00488 8.7e-99 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HPLIPDHJ_00489 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HPLIPDHJ_00490 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HPLIPDHJ_00491 0.0 nisT V ABC transporter
HPLIPDHJ_00492 6.9e-31
HPLIPDHJ_00493 8.1e-58
HPLIPDHJ_00494 3.5e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HPLIPDHJ_00495 8.8e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HPLIPDHJ_00497 5.3e-120 liaI S membrane
HPLIPDHJ_00498 2.7e-79 XK27_02470 K LytTr DNA-binding domain
HPLIPDHJ_00499 1.1e-101 yvdD 3.2.2.10 S Belongs to the LOG family
HPLIPDHJ_00500 3.4e-115 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HPLIPDHJ_00501 0.0 uup S ABC transporter, ATP-binding protein
HPLIPDHJ_00502 4.9e-243 G Bacterial extracellular solute-binding protein
HPLIPDHJ_00503 7.2e-14
HPLIPDHJ_00504 4.6e-22
HPLIPDHJ_00505 2.5e-153 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HPLIPDHJ_00506 1.9e-138 K LytTr DNA-binding domain
HPLIPDHJ_00507 2.7e-70 2.7.13.3 T GHKL domain
HPLIPDHJ_00508 1.7e-19 2.7.13.3 T GHKL domain
HPLIPDHJ_00509 7.9e-42 apfA 2.7.7.72, 3.6.1.61 F NUDIX domain
HPLIPDHJ_00510 2.4e-242 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HPLIPDHJ_00511 6e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HPLIPDHJ_00512 3.1e-189 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HPLIPDHJ_00513 3.4e-247 clcA P chloride
HPLIPDHJ_00514 7.2e-115
HPLIPDHJ_00515 2.5e-153
HPLIPDHJ_00516 1.4e-29 D nuclear chromosome segregation
HPLIPDHJ_00517 2.5e-147 D nuclear chromosome segregation
HPLIPDHJ_00518 5.3e-195 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HPLIPDHJ_00519 5.4e-95 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HPLIPDHJ_00520 7.5e-132 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HPLIPDHJ_00521 9.5e-81 folT S ECF transporter, substrate-specific component
HPLIPDHJ_00522 4.6e-137 fat 3.1.2.21 I Acyl-ACP thioesterase
HPLIPDHJ_00523 3.7e-154 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HPLIPDHJ_00524 4.4e-58 yabA L Involved in initiation control of chromosome replication
HPLIPDHJ_00525 1.4e-153 holB 2.7.7.7 L DNA polymerase III
HPLIPDHJ_00526 5e-51 yaaQ S Cyclic-di-AMP receptor
HPLIPDHJ_00527 1.2e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HPLIPDHJ_00528 9e-26 S Protein of unknown function (DUF2508)
HPLIPDHJ_00529 2.4e-107 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HPLIPDHJ_00530 5.9e-52 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HPLIPDHJ_00531 3.1e-296 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HPLIPDHJ_00532 2.3e-84 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HPLIPDHJ_00533 7.9e-36 S Protein conserved in bacteria
HPLIPDHJ_00534 7e-145
HPLIPDHJ_00535 3.6e-22
HPLIPDHJ_00536 5e-113 rsmC 2.1.1.172 J Methyltransferase
HPLIPDHJ_00537 3.6e-32
HPLIPDHJ_00538 1.2e-126 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
HPLIPDHJ_00539 9.4e-51 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HPLIPDHJ_00540 4.2e-81 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HPLIPDHJ_00541 4.6e-143 aatB ET ABC transporter substrate-binding protein
HPLIPDHJ_00542 1.3e-114 glnQ 3.6.3.21 E ABC transporter
HPLIPDHJ_00543 4.6e-109 glnP P ABC transporter permease
HPLIPDHJ_00544 3.6e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HPLIPDHJ_00545 5.3e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HPLIPDHJ_00546 1.5e-100 nusG K Participates in transcription elongation, termination and antitermination
HPLIPDHJ_00547 3.4e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HPLIPDHJ_00548 1.8e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HPLIPDHJ_00549 3.3e-189 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HPLIPDHJ_00550 1.1e-226 G Major Facilitator Superfamily
HPLIPDHJ_00551 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HPLIPDHJ_00552 3.1e-281 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HPLIPDHJ_00553 1.7e-34
HPLIPDHJ_00554 3.9e-88 yvrI K sigma factor activity
HPLIPDHJ_00555 2e-140 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HPLIPDHJ_00556 1.3e-78 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HPLIPDHJ_00557 6.1e-271 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HPLIPDHJ_00558 4.5e-288 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HPLIPDHJ_00559 3.5e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HPLIPDHJ_00560 4.7e-102 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HPLIPDHJ_00561 2.7e-21 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HPLIPDHJ_00562 3.5e-144 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HPLIPDHJ_00563 1.1e-264 pepC 3.4.22.40 E Peptidase C1-like family
HPLIPDHJ_00564 3e-09 ltrA S Bacterial low temperature requirement A protein (LtrA)
HPLIPDHJ_00565 2.2e-62 gadC E Contains amino acid permease domain
HPLIPDHJ_00566 2e-09 L PFAM Integrase catalytic region
HPLIPDHJ_00567 6.9e-25 L COG2963 Transposase and inactivated derivatives
HPLIPDHJ_00568 7.9e-149 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HPLIPDHJ_00569 2.5e-64 5.4.2.11 G Phosphoglycerate mutase family
HPLIPDHJ_00570 3e-78 6.3.3.2 S ASCH
HPLIPDHJ_00571 4.7e-140 2.4.2.3 F Phosphorylase superfamily
HPLIPDHJ_00572 5.7e-114 2.4.2.3 F Phosphorylase superfamily
HPLIPDHJ_00573 3.6e-45 csn 3.2.1.132 M Glycosyl hydrolase family 46
HPLIPDHJ_00574 2.2e-76 3.6.1.55 F NUDIX domain
HPLIPDHJ_00575 1.2e-112 2.7.1.89 M Phosphotransferase enzyme family
HPLIPDHJ_00576 1.3e-74 S AAA domain
HPLIPDHJ_00577 1.4e-36
HPLIPDHJ_00578 7.9e-99
HPLIPDHJ_00579 1e-17 XK27_07525 3.6.1.55 F NUDIX domain
HPLIPDHJ_00580 6.4e-57 2.3.1.57 K Acetyltransferase (GNAT) family
HPLIPDHJ_00581 3.1e-87 rimL J Acetyltransferase (GNAT) domain
HPLIPDHJ_00582 9.9e-36 aroD S Serine hydrolase (FSH1)
HPLIPDHJ_00583 5.3e-45
HPLIPDHJ_00584 9.2e-284 V ABC-type multidrug transport system, ATPase and permease components
HPLIPDHJ_00585 8.3e-184 P ABC transporter
HPLIPDHJ_00586 8.9e-132 qmcA O prohibitin homologues
HPLIPDHJ_00587 7.2e-35 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HPLIPDHJ_00588 1.7e-199 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HPLIPDHJ_00589 6.8e-28 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
HPLIPDHJ_00590 2.4e-53 rpiB 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
HPLIPDHJ_00591 3.5e-67 S SnoaL-like domain
HPLIPDHJ_00592 3.4e-34 C Oxidoreductase
HPLIPDHJ_00593 1.1e-56 C Oxidoreductase
HPLIPDHJ_00594 6.5e-54 drgA C nitroreductase
HPLIPDHJ_00595 1.5e-10 drgA C nitroreductase
HPLIPDHJ_00596 0.0 pepO 3.4.24.71 O Peptidase family M13
HPLIPDHJ_00597 2.9e-25 M Belongs to the glycosyl hydrolase 28 family
HPLIPDHJ_00598 8.1e-37 M Belongs to the glycosyl hydrolase 28 family
HPLIPDHJ_00600 3.6e-66 XK27_06780 V ABC transporter permease
HPLIPDHJ_00601 9.6e-92 XK27_06780 V ABC transporter permease
HPLIPDHJ_00602 7.4e-153 M Glycosyl transferases group 1
HPLIPDHJ_00603 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HPLIPDHJ_00604 7e-106 pncA Q Isochorismatase family
HPLIPDHJ_00605 1.2e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HPLIPDHJ_00606 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HPLIPDHJ_00607 4.8e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HPLIPDHJ_00608 1.6e-233 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HPLIPDHJ_00609 2e-180 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HPLIPDHJ_00610 8.7e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HPLIPDHJ_00611 1.2e-166 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HPLIPDHJ_00612 2.4e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HPLIPDHJ_00613 2.5e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HPLIPDHJ_00614 0.0 S Glycosyltransferase like family 2
HPLIPDHJ_00615 8.1e-202 csaB M Glycosyl transferases group 1
HPLIPDHJ_00616 1.6e-129 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HPLIPDHJ_00617 7.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
HPLIPDHJ_00618 3.6e-123 gntR1 K UTRA
HPLIPDHJ_00619 6.9e-185
HPLIPDHJ_00620 7.9e-51 P Rhodanese Homology Domain
HPLIPDHJ_00623 9.9e-166 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
HPLIPDHJ_00624 3.8e-111 K SIS domain
HPLIPDHJ_00625 5.6e-57 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HPLIPDHJ_00626 4.8e-166 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
HPLIPDHJ_00627 4.3e-31 yjgN S Bacterial protein of unknown function (DUF898)
HPLIPDHJ_00629 1.2e-83 M LysM domain protein
HPLIPDHJ_00630 1.1e-112 M LysM domain protein
HPLIPDHJ_00631 7.5e-57 psiE S Phosphate-starvation-inducible E
HPLIPDHJ_00632 2.3e-90 K acetyltransferase
HPLIPDHJ_00634 3.1e-161 yvgN C Aldo keto reductase
HPLIPDHJ_00635 3e-243 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HPLIPDHJ_00636 6.6e-75 S Uncharacterized protein conserved in bacteria (DUF2263)
HPLIPDHJ_00637 1.7e-190 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HPLIPDHJ_00638 0.0 lhr L DEAD DEAH box helicase
HPLIPDHJ_00639 3.5e-252 P P-loop Domain of unknown function (DUF2791)
HPLIPDHJ_00640 0.0 S TerB-C domain
HPLIPDHJ_00641 1.7e-104 4.1.1.44 S Carboxymuconolactone decarboxylase family
HPLIPDHJ_00642 1.9e-66
HPLIPDHJ_00643 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HPLIPDHJ_00644 3.6e-244 cycA E Amino acid permease
HPLIPDHJ_00645 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HPLIPDHJ_00646 2.6e-138 glcR K DeoR C terminal sensor domain
HPLIPDHJ_00647 4.2e-50 S Enterocin A Immunity
HPLIPDHJ_00648 8.9e-133 gntR K UbiC transcription regulator-associated domain protein
HPLIPDHJ_00649 2.7e-174 rihB 3.2.2.1 F Nucleoside
HPLIPDHJ_00650 9.1e-127 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HPLIPDHJ_00651 1.7e-157 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HPLIPDHJ_00652 2.6e-85 dps P Belongs to the Dps family
HPLIPDHJ_00653 6.6e-279 S C4-dicarboxylate anaerobic carrier
HPLIPDHJ_00654 2.8e-60 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HPLIPDHJ_00655 5.4e-108 phoU P Plays a role in the regulation of phosphate uptake
HPLIPDHJ_00656 1e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HPLIPDHJ_00657 2.6e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HPLIPDHJ_00658 2.4e-156 pstA P Phosphate transport system permease protein PstA
HPLIPDHJ_00659 2.1e-161 pstC P probably responsible for the translocation of the substrate across the membrane
HPLIPDHJ_00660 1.6e-157 pstS P Phosphate
HPLIPDHJ_00661 4e-95 K Acetyltransferase (GNAT) domain
HPLIPDHJ_00662 4.3e-127 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HPLIPDHJ_00663 1.1e-254 glnPH2 P ABC transporter permease
HPLIPDHJ_00664 9e-153 rssA S Phospholipase, patatin family
HPLIPDHJ_00665 2.7e-129 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
HPLIPDHJ_00666 2.4e-111 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
HPLIPDHJ_00667 1.7e-48 M Transport protein ComB
HPLIPDHJ_00668 1.1e-12 M Transport protein ComB
HPLIPDHJ_00669 4.2e-133 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HPLIPDHJ_00670 4.2e-184 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HPLIPDHJ_00671 8.9e-66 K LytTr DNA-binding domain
HPLIPDHJ_00672 4.5e-41 K LytTr DNA-binding domain
HPLIPDHJ_00673 1.4e-30 2.7.13.3 T GHKL domain
HPLIPDHJ_00674 8.1e-30 2.7.13.3 T GHKL domain
HPLIPDHJ_00678 8.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
HPLIPDHJ_00682 3.5e-74 S Putative adhesin
HPLIPDHJ_00683 4.6e-54 padR K Virulence activator alpha C-term
HPLIPDHJ_00684 1.8e-28 padC Q Phenolic acid decarboxylase
HPLIPDHJ_00685 4.3e-97 EGP Major facilitator Superfamily
HPLIPDHJ_00686 5.7e-45 EGP Major facilitator Superfamily
HPLIPDHJ_00687 1.6e-260 pgi 5.3.1.9 G Belongs to the GPI family
HPLIPDHJ_00688 2.1e-103 vanZ V VanZ like family
HPLIPDHJ_00689 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HPLIPDHJ_00690 1.9e-264 T PhoQ Sensor
HPLIPDHJ_00691 7.1e-127 K Transcriptional regulatory protein, C terminal
HPLIPDHJ_00692 6e-67 S SdpI/YhfL protein family
HPLIPDHJ_00693 2.8e-190 manA 5.3.1.8 G mannose-6-phosphate isomerase
HPLIPDHJ_00694 1.9e-138 patB 4.4.1.8 E Aminotransferase, class I
HPLIPDHJ_00695 1.4e-68 patB 4.4.1.8 E Aminotransferase, class I
HPLIPDHJ_00696 1.3e-90 M Protein of unknown function (DUF3737)
HPLIPDHJ_00697 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
HPLIPDHJ_00699 3.3e-225 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HPLIPDHJ_00700 1.2e-183 ytxK 2.1.1.72 L N-6 DNA Methylase
HPLIPDHJ_00701 1.4e-84 comGF U Putative Competence protein ComGF
HPLIPDHJ_00702 1.7e-10
HPLIPDHJ_00703 2e-57
HPLIPDHJ_00704 1.2e-40 comGC U Required for transformation and DNA binding
HPLIPDHJ_00705 7.8e-172 comGB NU type II secretion system
HPLIPDHJ_00706 1.4e-178 comGA NU Type II IV secretion system protein
HPLIPDHJ_00707 1.5e-132 yebC K Transcriptional regulatory protein
HPLIPDHJ_00708 8e-96 S VanZ like family
HPLIPDHJ_00709 6.2e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HPLIPDHJ_00710 7.2e-161 znuA P Belongs to the bacterial solute-binding protein 9 family
HPLIPDHJ_00711 5.7e-280 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HPLIPDHJ_00712 4.4e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HPLIPDHJ_00713 1.8e-19 spoVK O ATPase family associated with various cellular activities (AAA)
HPLIPDHJ_00714 7.7e-51 spoVK O ATPase family associated with various cellular activities (AAA)
HPLIPDHJ_00715 3.2e-34 spoVK O ATPase family associated with various cellular activities (AAA)
HPLIPDHJ_00716 0.0 pacL 3.6.3.8 P P-type ATPase
HPLIPDHJ_00717 1.7e-223 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HPLIPDHJ_00718 5.8e-253 epsU S Polysaccharide biosynthesis protein
HPLIPDHJ_00719 2.5e-132 M Glycosyltransferase sugar-binding region containing DXD motif
HPLIPDHJ_00720 9.1e-83 ydcK S Belongs to the SprT family
HPLIPDHJ_00722 8.1e-103 S ECF transporter, substrate-specific component
HPLIPDHJ_00723 1.8e-110 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
HPLIPDHJ_00724 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HPLIPDHJ_00725 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HPLIPDHJ_00726 8.5e-207 camS S sex pheromone
HPLIPDHJ_00727 3.3e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HPLIPDHJ_00728 2.4e-270 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HPLIPDHJ_00729 2.3e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HPLIPDHJ_00730 1.2e-166 yegS 2.7.1.107 G Lipid kinase
HPLIPDHJ_00732 3.4e-149 S hydrolase
HPLIPDHJ_00733 2.4e-116 GT2,GT4 M family 8
HPLIPDHJ_00734 1.2e-116 ybhL S Belongs to the BI1 family
HPLIPDHJ_00735 2.4e-142 cbiQ P cobalt transport
HPLIPDHJ_00736 0.0 ykoD P ABC transporter, ATP-binding protein
HPLIPDHJ_00737 1.9e-95 S UPF0397 protein
HPLIPDHJ_00738 6e-157 salL 2.5.1.63, 2.5.1.94 K S-adenosyl-l-methionine hydroxide adenosyltransferase
HPLIPDHJ_00739 2.3e-238 nhaC C Na H antiporter NhaC
HPLIPDHJ_00740 1.4e-127 mutF V ABC transporter, ATP-binding protein
HPLIPDHJ_00741 5.8e-118 spaE S ABC-2 family transporter protein
HPLIPDHJ_00742 2.2e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HPLIPDHJ_00743 3.4e-129 3.6.1.13, 3.6.1.55 F NUDIX domain
HPLIPDHJ_00744 4.9e-268 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HPLIPDHJ_00745 5.5e-103 pncA Q Isochorismatase family
HPLIPDHJ_00746 6.8e-193 L Recombinase
HPLIPDHJ_00747 2.7e-15
HPLIPDHJ_00748 5.7e-16
HPLIPDHJ_00749 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
HPLIPDHJ_00750 5.1e-34 copZ C Heavy-metal-associated domain
HPLIPDHJ_00751 2.7e-94 dps P Belongs to the Dps family
HPLIPDHJ_00752 8.9e-113 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HPLIPDHJ_00753 3.8e-26 ung2 3.2.2.27 L Uracil-DNA glycosylase
HPLIPDHJ_00754 7.3e-189 V Beta-lactamase
HPLIPDHJ_00755 2.4e-139 neo 2.7.1.87, 2.7.1.95 F Belongs to the aminoglycoside phosphotransferase family
HPLIPDHJ_00756 1.8e-11 adk 2.7.4.3 F adenylate kinase activity
HPLIPDHJ_00758 3.3e-155 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HPLIPDHJ_00759 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HPLIPDHJ_00760 3.6e-55 yheA S Belongs to the UPF0342 family
HPLIPDHJ_00761 4.5e-214 yhaO L Ser Thr phosphatase family protein
HPLIPDHJ_00762 0.0 L AAA domain
HPLIPDHJ_00763 1.3e-182 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
HPLIPDHJ_00764 5.1e-146 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HPLIPDHJ_00765 9.5e-24 S YtxH-like protein
HPLIPDHJ_00766 1.3e-50
HPLIPDHJ_00767 9.2e-77 hit FG Scavenger mRNA decapping enzyme C-term binding
HPLIPDHJ_00768 3.1e-133 ecsA V ABC transporter, ATP-binding protein
HPLIPDHJ_00769 1.1e-223 ecsB U ABC transporter
HPLIPDHJ_00770 8e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HPLIPDHJ_00771 3.2e-48
HPLIPDHJ_00772 8.9e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HPLIPDHJ_00773 2e-120 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HPLIPDHJ_00774 8.6e-128 ymfC K UTRA
HPLIPDHJ_00775 1.1e-255 3.5.1.18 E Peptidase family M20/M25/M40
HPLIPDHJ_00776 2.4e-178 aspG 3.4.19.5, 3.5.1.1, 3.5.1.26 E Asparaginase
HPLIPDHJ_00777 2.2e-93 S Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)
HPLIPDHJ_00778 2.1e-196 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPLIPDHJ_00779 9.7e-115 cutC P Participates in the control of copper homeostasis
HPLIPDHJ_00780 5.3e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HPLIPDHJ_00781 1.2e-62 K UTRA
HPLIPDHJ_00782 2.8e-42 K UTRA
HPLIPDHJ_00783 3.5e-29 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HPLIPDHJ_00784 1.5e-17 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HPLIPDHJ_00785 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HPLIPDHJ_00786 5e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HPLIPDHJ_00787 6.6e-102 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HPLIPDHJ_00788 2.3e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HPLIPDHJ_00789 1.3e-243 dnaB L Replication initiation and membrane attachment
HPLIPDHJ_00790 6.2e-160 dnaI L Primosomal protein DnaI
HPLIPDHJ_00791 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HPLIPDHJ_00792 1.1e-53 K LytTr DNA-binding domain
HPLIPDHJ_00793 2.4e-37 S Protein of unknown function (DUF3021)
HPLIPDHJ_00794 4e-87 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HPLIPDHJ_00795 2.4e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HPLIPDHJ_00796 6.6e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HPLIPDHJ_00797 3e-103 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HPLIPDHJ_00798 2.5e-12 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HPLIPDHJ_00799 4e-87 yqeG S HAD phosphatase, family IIIA
HPLIPDHJ_00800 1.8e-209 yqeH S Ribosome biogenesis GTPase YqeH
HPLIPDHJ_00801 1e-116 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HPLIPDHJ_00802 3.9e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HPLIPDHJ_00803 3.7e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HPLIPDHJ_00804 6e-216 ylbM S Belongs to the UPF0348 family
HPLIPDHJ_00805 1.7e-91 yceD S Uncharacterized ACR, COG1399
HPLIPDHJ_00806 1.4e-130 K response regulator
HPLIPDHJ_00807 7.8e-272 arlS 2.7.13.3 T Histidine kinase
HPLIPDHJ_00808 1.5e-167 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HPLIPDHJ_00809 1.5e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HPLIPDHJ_00810 9.9e-135 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HPLIPDHJ_00811 1.4e-62 yodB K Transcriptional regulator, HxlR family
HPLIPDHJ_00812 3.8e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HPLIPDHJ_00813 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HPLIPDHJ_00814 2.7e-202 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HPLIPDHJ_00815 4e-65 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HPLIPDHJ_00816 0.0 S membrane
HPLIPDHJ_00817 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HPLIPDHJ_00818 7.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HPLIPDHJ_00819 1.2e-89 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HPLIPDHJ_00820 1.7e-117 gluP 3.4.21.105 S Rhomboid family
HPLIPDHJ_00821 7.9e-35 yqgQ S Bacterial protein of unknown function (DUF910)
HPLIPDHJ_00822 4.4e-57 yqhL P Rhodanese-like protein
HPLIPDHJ_00823 8.1e-19 S Protein of unknown function (DUF3042)
HPLIPDHJ_00824 1.8e-167 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HPLIPDHJ_00825 4.3e-258 glnA 6.3.1.2 E glutamine synthetase
HPLIPDHJ_00826 8.2e-205 EGP Major facilitator Superfamily
HPLIPDHJ_00827 5.8e-149 S haloacid dehalogenase-like hydrolase
HPLIPDHJ_00829 1.3e-179 D Alpha beta
HPLIPDHJ_00830 3.1e-212 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
HPLIPDHJ_00831 2.1e-214 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HPLIPDHJ_00832 2.4e-217 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HPLIPDHJ_00833 8e-260 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HPLIPDHJ_00834 1.9e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
HPLIPDHJ_00835 2e-111 ygaC J Belongs to the UPF0374 family
HPLIPDHJ_00836 1.1e-86
HPLIPDHJ_00837 8.8e-78
HPLIPDHJ_00838 3.4e-155 hlyX S Transporter associated domain
HPLIPDHJ_00839 1.5e-302 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HPLIPDHJ_00840 1.1e-43 XK27_09445 S Domain of unknown function (DUF1827)
HPLIPDHJ_00841 0.0 clpE O Belongs to the ClpA ClpB family
HPLIPDHJ_00842 5.9e-25
HPLIPDHJ_00843 4.2e-40 ptsH G phosphocarrier protein HPR
HPLIPDHJ_00844 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HPLIPDHJ_00845 1.2e-65 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HPLIPDHJ_00846 2.1e-117 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HPLIPDHJ_00847 2.4e-156 coiA 3.6.4.12 S Competence protein
HPLIPDHJ_00848 3.6e-103 yjbH Q Thioredoxin
HPLIPDHJ_00849 1.3e-108 yjbK S CYTH
HPLIPDHJ_00850 5.2e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
HPLIPDHJ_00851 1.3e-148 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HPLIPDHJ_00852 1.4e-167 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HPLIPDHJ_00853 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
HPLIPDHJ_00854 5.4e-231 N Uncharacterized conserved protein (DUF2075)
HPLIPDHJ_00855 1.1e-200 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HPLIPDHJ_00856 1.1e-62 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HPLIPDHJ_00857 4.7e-208 yubA S AI-2E family transporter
HPLIPDHJ_00858 4.6e-105 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HPLIPDHJ_00859 4.3e-74 WQ51_03320 S Protein of unknown function (DUF1149)
HPLIPDHJ_00860 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HPLIPDHJ_00861 3.3e-225 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
HPLIPDHJ_00862 2.3e-226 S Peptidase M16
HPLIPDHJ_00863 5.4e-130 IQ Enoyl-(Acyl carrier protein) reductase
HPLIPDHJ_00864 6e-122 ymfM S Helix-turn-helix domain
HPLIPDHJ_00865 3e-96 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HPLIPDHJ_00866 1.4e-193 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HPLIPDHJ_00867 5.8e-201 rny S Endoribonuclease that initiates mRNA decay
HPLIPDHJ_00868 1.6e-192 tagO 2.7.8.33, 2.7.8.35 M transferase
HPLIPDHJ_00869 1.4e-116 yvyE 3.4.13.9 S YigZ family
HPLIPDHJ_00870 1.3e-221 comFA L Helicase C-terminal domain protein
HPLIPDHJ_00871 1.7e-122 comFC S Competence protein
HPLIPDHJ_00872 1.3e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HPLIPDHJ_00873 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HPLIPDHJ_00874 1.7e-182 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HPLIPDHJ_00875 7.6e-24
HPLIPDHJ_00876 4e-173 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HPLIPDHJ_00877 2.9e-156 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HPLIPDHJ_00878 8.2e-185 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HPLIPDHJ_00879 1e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HPLIPDHJ_00880 2.4e-189 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HPLIPDHJ_00881 1.3e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HPLIPDHJ_00882 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HPLIPDHJ_00883 6.5e-176 lacR K Transcriptional regulator
HPLIPDHJ_00884 0.0 lacS G Transporter
HPLIPDHJ_00885 0.0 lacZ 3.2.1.23 G -beta-galactosidase
HPLIPDHJ_00886 1.1e-220 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HPLIPDHJ_00887 3.7e-287 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HPLIPDHJ_00888 3e-192 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HPLIPDHJ_00889 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HPLIPDHJ_00890 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HPLIPDHJ_00891 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HPLIPDHJ_00892 8.1e-91 S Short repeat of unknown function (DUF308)
HPLIPDHJ_00893 1.7e-159 rapZ S Displays ATPase and GTPase activities
HPLIPDHJ_00894 1.7e-193 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HPLIPDHJ_00895 6.2e-171 whiA K May be required for sporulation
HPLIPDHJ_00896 2.7e-100 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HPLIPDHJ_00897 2e-277 ycaM E amino acid
HPLIPDHJ_00899 1.4e-187 cggR K Putative sugar-binding domain
HPLIPDHJ_00900 3.2e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HPLIPDHJ_00901 1e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HPLIPDHJ_00902 1.1e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HPLIPDHJ_00903 4e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HPLIPDHJ_00904 1.9e-28 secG U Preprotein translocase
HPLIPDHJ_00905 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HPLIPDHJ_00906 3.3e-77 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HPLIPDHJ_00907 2.3e-104 3.2.2.20 K acetyltransferase
HPLIPDHJ_00908 9.2e-77
HPLIPDHJ_00909 5.8e-94
HPLIPDHJ_00910 7.5e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
HPLIPDHJ_00911 2.8e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HPLIPDHJ_00912 1.1e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HPLIPDHJ_00913 2.2e-84 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HPLIPDHJ_00914 1.2e-99 dnaQ 2.7.7.7 L DNA polymerase III
HPLIPDHJ_00915 8.4e-165 murB 1.3.1.98 M Cell wall formation
HPLIPDHJ_00916 2.1e-202 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HPLIPDHJ_00917 1.2e-130 potB P ABC transporter permease
HPLIPDHJ_00918 2.9e-137 potC P ABC transporter permease
HPLIPDHJ_00919 1.2e-207 potD P ABC transporter
HPLIPDHJ_00920 1.3e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HPLIPDHJ_00921 1.7e-171 ybbR S YbbR-like protein
HPLIPDHJ_00922 4.5e-255 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HPLIPDHJ_00923 1.7e-148 S Sucrose-6F-phosphate phosphohydrolase
HPLIPDHJ_00924 2.7e-64 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HPLIPDHJ_00925 7.6e-61 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HPLIPDHJ_00926 1.2e-195 S Putative adhesin
HPLIPDHJ_00927 3.4e-113
HPLIPDHJ_00928 1.1e-144 yisY 1.11.1.10 S Alpha/beta hydrolase family
HPLIPDHJ_00945 5.5e-59
HPLIPDHJ_00957 5.5e-217 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
HPLIPDHJ_00958 3.1e-195 cpoA GT4 M Glycosyltransferase, group 1 family protein
HPLIPDHJ_00959 6.5e-182 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HPLIPDHJ_00960 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HPLIPDHJ_00961 5.3e-84 L Transposase
HPLIPDHJ_00962 6.3e-59 L Transposase
HPLIPDHJ_00963 2.3e-52 yveB 2.7.4.29 I PAP2 superfamily
HPLIPDHJ_00964 3.4e-191 ampC V Beta-lactamase
HPLIPDHJ_00967 7.2e-69
HPLIPDHJ_00968 8e-24 EGP Major facilitator Superfamily
HPLIPDHJ_00969 2.5e-15 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
HPLIPDHJ_00970 7.9e-82 atl 3.2.1.96, 3.5.1.28 GH73 UW LPXTG-motif cell wall anchor domain protein
HPLIPDHJ_00971 9e-145 L Transposase
HPLIPDHJ_00972 1e-45 L Helix-turn-helix domain
HPLIPDHJ_00975 6.8e-262 E amino acid
HPLIPDHJ_00976 0.0 S domain, Protein
HPLIPDHJ_00977 1.5e-191 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPLIPDHJ_00978 5.1e-99 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
HPLIPDHJ_00979 1.6e-208 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HPLIPDHJ_00980 1.4e-248 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
HPLIPDHJ_00981 1.2e-170 K AI-2E family transporter
HPLIPDHJ_00982 1.7e-27
HPLIPDHJ_00983 1.3e-138 S Alpha beta hydrolase
HPLIPDHJ_00984 0.0 L Helicase C-terminal domain protein
HPLIPDHJ_00985 1.3e-159 xth 3.1.11.2 L exodeoxyribonuclease III
HPLIPDHJ_00986 5.5e-40 S Transglycosylase associated protein
HPLIPDHJ_00988 1.1e-207 XK27_02480 EGP Major facilitator Superfamily
HPLIPDHJ_00989 3.8e-138 ropB K Helix-turn-helix XRE-family like proteins
HPLIPDHJ_00990 3e-265 pepO 3.4.24.71 O Peptidase family M13
HPLIPDHJ_00991 1.4e-82 pepO 3.4.24.71 O Peptidase family M13
HPLIPDHJ_00992 1.1e-234 clcA P chloride
HPLIPDHJ_00993 0.0 tetP J elongation factor G
HPLIPDHJ_00994 3.9e-137 ropB K Helix-turn-helix domain
HPLIPDHJ_00995 5.8e-286 V ABC-type multidrug transport system, ATPase and permease components
HPLIPDHJ_00996 3.5e-17
HPLIPDHJ_00997 5.2e-153 yitS S EDD domain protein, DegV family
HPLIPDHJ_00998 1.3e-136 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HPLIPDHJ_00999 7.4e-121 S Protein of unknown function (DUF975)
HPLIPDHJ_01000 4.8e-114 ywnB S NAD(P)H-binding
HPLIPDHJ_01001 1.8e-90 arbZ I Acyltransferase
HPLIPDHJ_01002 9.7e-45 arbZ I Acyltransferase
HPLIPDHJ_01003 3.9e-215 S Sterol carrier protein domain
HPLIPDHJ_01005 2.5e-237 steT E amino acid
HPLIPDHJ_01007 0.0
HPLIPDHJ_01008 5e-215 I Protein of unknown function (DUF2974)
HPLIPDHJ_01009 3.2e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HPLIPDHJ_01010 1.6e-244 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HPLIPDHJ_01011 4.8e-76 rplI J Binds to the 23S rRNA
HPLIPDHJ_01012 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HPLIPDHJ_01013 2.2e-157 corA P CorA-like Mg2+ transporter protein
HPLIPDHJ_01014 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HPLIPDHJ_01015 7.3e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HPLIPDHJ_01016 9.4e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
HPLIPDHJ_01017 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HPLIPDHJ_01018 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HPLIPDHJ_01019 2.2e-207 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HPLIPDHJ_01020 1.2e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HPLIPDHJ_01021 9.1e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HPLIPDHJ_01022 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HPLIPDHJ_01023 4.6e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HPLIPDHJ_01024 1.6e-149 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HPLIPDHJ_01025 9.5e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HPLIPDHJ_01026 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HPLIPDHJ_01027 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HPLIPDHJ_01028 5.1e-270 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HPLIPDHJ_01029 1.1e-286 clcA P chloride
HPLIPDHJ_01030 8.9e-185 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HPLIPDHJ_01031 1.7e-126 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HPLIPDHJ_01032 9.8e-162 add 3.5.4.2, 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HPLIPDHJ_01033 7.2e-213 pbuG S permease
HPLIPDHJ_01034 7.6e-287 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HPLIPDHJ_01035 1.6e-67 S Iron-sulphur cluster biosynthesis
HPLIPDHJ_01036 7.4e-66 K Acetyltransferase (GNAT) domain
HPLIPDHJ_01037 9.4e-247 ynbB 4.4.1.1 P aluminum resistance
HPLIPDHJ_01038 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
HPLIPDHJ_01039 4.4e-280 E Amino acid permease
HPLIPDHJ_01040 0.0 copA 3.6.3.54 P P-type ATPase
HPLIPDHJ_01041 8.3e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HPLIPDHJ_01042 2.9e-42 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HPLIPDHJ_01043 8.1e-73 atkY K Penicillinase repressor
HPLIPDHJ_01044 2.4e-90
HPLIPDHJ_01045 5.9e-81
HPLIPDHJ_01046 4.4e-68 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HPLIPDHJ_01047 2.1e-74 K Bacteriophage CI repressor helix-turn-helix domain
HPLIPDHJ_01048 1.6e-225 pbuG S permease
HPLIPDHJ_01049 4.9e-45 I bis(5'-adenosyl)-triphosphatase activity
HPLIPDHJ_01050 4.4e-231 pbuG S permease
HPLIPDHJ_01051 4.3e-127 K helix_turn_helix, mercury resistance
HPLIPDHJ_01052 4.4e-231 pbuG S permease
HPLIPDHJ_01053 2e-166 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HPLIPDHJ_01054 7.5e-28 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HPLIPDHJ_01055 2.4e-124 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HPLIPDHJ_01056 2.5e-118 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HPLIPDHJ_01057 1.1e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HPLIPDHJ_01058 9.2e-158 yeaE S Aldo/keto reductase family
HPLIPDHJ_01059 7.1e-125 S membrane transporter protein
HPLIPDHJ_01060 0.0 sacX 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HPLIPDHJ_01061 1.9e-148 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HPLIPDHJ_01062 4e-166 yleB 4.2.1.126 S Bacterial protein of unknown function (DUF871)
HPLIPDHJ_01063 6.1e-149 K Helix-turn-helix domain, rpiR family
HPLIPDHJ_01064 1.7e-193 tcsA S ABC transporter substrate-binding protein PnrA-like
HPLIPDHJ_01065 1.9e-167 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
HPLIPDHJ_01066 1.2e-174 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HPLIPDHJ_01067 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HPLIPDHJ_01068 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HPLIPDHJ_01069 4.2e-181 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HPLIPDHJ_01070 2.5e-269 cydA 1.10.3.14 C ubiquinol oxidase
HPLIPDHJ_01071 0.0 macB_3 V ABC transporter, ATP-binding protein
HPLIPDHJ_01072 1.1e-198 S DUF218 domain
HPLIPDHJ_01073 4.2e-102 S CAAX protease self-immunity
HPLIPDHJ_01074 5.1e-95 S Protein of unknown function (DUF1440)
HPLIPDHJ_01075 1e-265 G PTS system Galactitol-specific IIC component
HPLIPDHJ_01076 1.9e-15
HPLIPDHJ_01077 4.6e-14
HPLIPDHJ_01078 1.9e-83 S Protein of unknown function (DUF805)
HPLIPDHJ_01079 2.5e-113 S Protein of unknown function (DUF969)
HPLIPDHJ_01080 3.8e-157 S Protein of unknown function (DUF979)
HPLIPDHJ_01081 4.2e-118 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HPLIPDHJ_01082 2e-30
HPLIPDHJ_01084 8.1e-28
HPLIPDHJ_01085 2.9e-159 mutR K Helix-turn-helix XRE-family like proteins
HPLIPDHJ_01086 4.2e-251 V ABC transporter transmembrane region
HPLIPDHJ_01088 4.6e-200 napA P Sodium/hydrogen exchanger family
HPLIPDHJ_01089 0.0 cadA P P-type ATPase
HPLIPDHJ_01090 5.7e-75 ykuL S (CBS) domain
HPLIPDHJ_01091 5.8e-17
HPLIPDHJ_01092 4.1e-201 ywhK S Membrane
HPLIPDHJ_01093 6.6e-39
HPLIPDHJ_01095 1.1e-289 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HPLIPDHJ_01096 3.9e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
HPLIPDHJ_01097 6.7e-37 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HPLIPDHJ_01098 9.9e-252 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HPLIPDHJ_01099 1.1e-139 pbpX2 V Beta-lactamase
HPLIPDHJ_01100 2e-214 lmrP E Major Facilitator Superfamily
HPLIPDHJ_01101 3.5e-38
HPLIPDHJ_01102 3.7e-230 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPLIPDHJ_01103 7.4e-169 S Alpha/beta hydrolase of unknown function (DUF915)
HPLIPDHJ_01104 0.0 clpE2 O AAA domain (Cdc48 subfamily)
HPLIPDHJ_01105 1.7e-249 yfnA E Amino Acid
HPLIPDHJ_01108 4.3e-275 yjeM E Amino Acid
HPLIPDHJ_01109 1.4e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HPLIPDHJ_01110 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HPLIPDHJ_01111 1.2e-123 srtA 3.4.22.70 M sortase family
HPLIPDHJ_01112 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HPLIPDHJ_01113 1.8e-172 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HPLIPDHJ_01114 0.0 dnaK O Heat shock 70 kDa protein
HPLIPDHJ_01115 4.2e-77 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HPLIPDHJ_01116 4.7e-191 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HPLIPDHJ_01117 7.9e-22 S GyrI-like small molecule binding domain
HPLIPDHJ_01118 7.7e-31 S GyrI-like small molecule binding domain
HPLIPDHJ_01119 8.8e-276 lsa S ABC transporter
HPLIPDHJ_01120 3e-173 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HPLIPDHJ_01121 8.8e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HPLIPDHJ_01122 5.1e-60 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HPLIPDHJ_01123 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HPLIPDHJ_01124 7.1e-47 rplGA J ribosomal protein
HPLIPDHJ_01125 1.5e-46 ylxR K Protein of unknown function (DUF448)
HPLIPDHJ_01126 3e-218 nusA K Participates in both transcription termination and antitermination
HPLIPDHJ_01127 5.2e-81 rimP J Required for maturation of 30S ribosomal subunits
HPLIPDHJ_01128 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HPLIPDHJ_01129 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HPLIPDHJ_01130 1.5e-228 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HPLIPDHJ_01131 2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
HPLIPDHJ_01132 7.2e-135 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HPLIPDHJ_01133 2.6e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HPLIPDHJ_01134 1.8e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HPLIPDHJ_01135 9.1e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HPLIPDHJ_01136 5.8e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
HPLIPDHJ_01137 2.2e-193 yabB 2.1.1.223 L Methyltransferase small domain
HPLIPDHJ_01138 3.7e-116 plsC 2.3.1.51 I Acyltransferase
HPLIPDHJ_01139 1.6e-227 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HPLIPDHJ_01140 3e-283 mdlB V ABC transporter
HPLIPDHJ_01141 0.0 mdlA V ABC transporter
HPLIPDHJ_01142 1.9e-30 yneF S Uncharacterised protein family (UPF0154)
HPLIPDHJ_01143 9.4e-34 ynzC S UPF0291 protein
HPLIPDHJ_01144 1e-113 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HPLIPDHJ_01145 1.7e-116 ung2 3.2.2.27 L Uracil-DNA glycosylase
HPLIPDHJ_01146 3.9e-72 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HPLIPDHJ_01147 2.3e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HPLIPDHJ_01148 1e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HPLIPDHJ_01149 1.7e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HPLIPDHJ_01150 3.1e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HPLIPDHJ_01151 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HPLIPDHJ_01152 1.1e-227 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HPLIPDHJ_01153 4.9e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HPLIPDHJ_01154 1.8e-283 pipD E Dipeptidase
HPLIPDHJ_01155 2.5e-165 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HPLIPDHJ_01156 0.0 smc D Required for chromosome condensation and partitioning
HPLIPDHJ_01157 1.1e-121 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HPLIPDHJ_01158 0.0 oppA E ABC transporter substrate-binding protein
HPLIPDHJ_01159 0.0 oppA E ABC transporter substrate-binding protein
HPLIPDHJ_01160 1.3e-160 oppC P Binding-protein-dependent transport system inner membrane component
HPLIPDHJ_01161 2e-177 oppB P ABC transporter permease
HPLIPDHJ_01162 7.8e-177 oppF P Belongs to the ABC transporter superfamily
HPLIPDHJ_01163 2e-191 oppD P Belongs to the ABC transporter superfamily
HPLIPDHJ_01164 4.4e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HPLIPDHJ_01165 1.7e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HPLIPDHJ_01166 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HPLIPDHJ_01167 6.4e-304 yloV S DAK2 domain fusion protein YloV
HPLIPDHJ_01168 1.4e-57 asp S Asp23 family, cell envelope-related function
HPLIPDHJ_01169 1.2e-25 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HPLIPDHJ_01170 1.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
HPLIPDHJ_01171 5.9e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HPLIPDHJ_01172 6.1e-160 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HPLIPDHJ_01173 0.0 KLT serine threonine protein kinase
HPLIPDHJ_01174 2.7e-140 stp 3.1.3.16 T phosphatase
HPLIPDHJ_01175 1.1e-237 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HPLIPDHJ_01176 1.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HPLIPDHJ_01177 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HPLIPDHJ_01178 2.3e-31 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HPLIPDHJ_01179 8.1e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HPLIPDHJ_01180 1e-47
HPLIPDHJ_01181 5.9e-289 recN L May be involved in recombinational repair of damaged DNA
HPLIPDHJ_01182 5.1e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HPLIPDHJ_01183 3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HPLIPDHJ_01184 1.2e-33 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HPLIPDHJ_01185 1.7e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HPLIPDHJ_01186 6e-149 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HPLIPDHJ_01187 3.6e-67 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HPLIPDHJ_01188 8.2e-73 yqhY S Asp23 family, cell envelope-related function
HPLIPDHJ_01189 1.1e-101 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HPLIPDHJ_01190 2.7e-197 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HPLIPDHJ_01191 2.8e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HPLIPDHJ_01192 2e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HPLIPDHJ_01193 3.5e-58 arsC 1.20.4.1 P Belongs to the ArsC family
HPLIPDHJ_01194 1.9e-150 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HPLIPDHJ_01195 2.9e-214 S Uncharacterized protein conserved in bacteria (DUF2325)
HPLIPDHJ_01196 1.8e-11
HPLIPDHJ_01197 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HPLIPDHJ_01198 1.3e-91 S ECF-type riboflavin transporter, S component
HPLIPDHJ_01199 3.1e-142 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HPLIPDHJ_01200 5.5e-80
HPLIPDHJ_01201 1.2e-120 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HPLIPDHJ_01202 1.8e-307 S Predicted membrane protein (DUF2207)
HPLIPDHJ_01203 2.4e-172 I Carboxylesterase family
HPLIPDHJ_01204 3.5e-252 pepC 3.4.22.40 E Peptidase C1-like family
HPLIPDHJ_01205 2.3e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
HPLIPDHJ_01206 3.2e-150 oppA E ABC transporter substrate-binding protein
HPLIPDHJ_01207 9.9e-64 oppA E ABC transporter substrate-binding protein
HPLIPDHJ_01208 1.9e-77 K MerR HTH family regulatory protein
HPLIPDHJ_01209 2.3e-265 lmrB EGP Major facilitator Superfamily
HPLIPDHJ_01210 1.3e-85 S Domain of unknown function (DUF4811)
HPLIPDHJ_01211 1.1e-139 ppm1 GT2 M Glycosyl transferase family 2
HPLIPDHJ_01212 1.1e-104 fic D Fic/DOC family
HPLIPDHJ_01213 5.2e-69
HPLIPDHJ_01214 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HPLIPDHJ_01216 1.6e-140 S haloacid dehalogenase-like hydrolase
HPLIPDHJ_01217 0.0 pepN 3.4.11.2 E aminopeptidase
HPLIPDHJ_01218 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HPLIPDHJ_01219 1.5e-223 sptS 2.7.13.3 T Histidine kinase
HPLIPDHJ_01220 4e-116 K response regulator
HPLIPDHJ_01221 3.9e-113 2.7.6.5 T Region found in RelA / SpoT proteins
HPLIPDHJ_01222 1.8e-107 ltrA S Bacterial low temperature requirement A protein (LtrA)
HPLIPDHJ_01223 1.8e-66 O OsmC-like protein
HPLIPDHJ_01224 2.6e-283 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HPLIPDHJ_01225 7.5e-180 E ABC transporter, ATP-binding protein
HPLIPDHJ_01226 2.1e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HPLIPDHJ_01227 2e-161 yihY S Belongs to the UPF0761 family
HPLIPDHJ_01228 9.7e-160 map 3.4.11.18 E Methionine Aminopeptidase
HPLIPDHJ_01229 2.5e-77 fld C Flavodoxin
HPLIPDHJ_01230 1e-87 gtcA S Teichoic acid glycosylation protein
HPLIPDHJ_01231 1.6e-213 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HPLIPDHJ_01234 4.3e-250 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPLIPDHJ_01235 1.5e-204 yfmL 3.6.4.13 L DEAD DEAH box helicase
HPLIPDHJ_01236 6.4e-136 M Glycosyl hydrolases family 25
HPLIPDHJ_01237 4.8e-230 potE E amino acid
HPLIPDHJ_01238 3.4e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HPLIPDHJ_01239 6.2e-236 yhdP S Transporter associated domain
HPLIPDHJ_01240 6.5e-125
HPLIPDHJ_01241 3.1e-116 C nitroreductase
HPLIPDHJ_01242 4.7e-213 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HPLIPDHJ_01243 4.5e-33 S Protein of unknown function (DUF2922)
HPLIPDHJ_01244 3.3e-24
HPLIPDHJ_01245 1.2e-109
HPLIPDHJ_01246 1.6e-70
HPLIPDHJ_01247 0.0 kup P Transport of potassium into the cell
HPLIPDHJ_01248 0.0 kup P Transport of potassium into the cell
HPLIPDHJ_01249 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
HPLIPDHJ_01250 4.4e-308 S Bacterial membrane protein, YfhO
HPLIPDHJ_01251 0.0 pepO 3.4.24.71 O Peptidase family M13
HPLIPDHJ_01252 0.0 fruA 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HPLIPDHJ_01253 6.6e-165 pfkB 2.7.1.11, 2.7.1.56 H pfkB family carbohydrate kinase
HPLIPDHJ_01254 3.8e-134 rpl K Helix-turn-helix domain, rpiR family
HPLIPDHJ_01255 9.5e-167 D nuclear chromosome segregation
HPLIPDHJ_01256 3e-184 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
HPLIPDHJ_01257 4.4e-225 yttB EGP Major facilitator Superfamily
HPLIPDHJ_01258 3.5e-227 XK27_04775 S PAS domain
HPLIPDHJ_01259 2e-103 S Iron-sulfur cluster assembly protein
HPLIPDHJ_01260 9e-130 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HPLIPDHJ_01261 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HPLIPDHJ_01262 3.7e-262 yxbA 6.3.1.12 S ATP-grasp enzyme
HPLIPDHJ_01263 0.0 asnB 6.3.5.4 E Asparagine synthase
HPLIPDHJ_01264 9.9e-274 S Calcineurin-like phosphoesterase
HPLIPDHJ_01265 7.3e-83
HPLIPDHJ_01266 9.2e-147 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HPLIPDHJ_01267 2.7e-130 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HPLIPDHJ_01268 1.8e-139 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HPLIPDHJ_01269 1.2e-166 phnD P Phosphonate ABC transporter
HPLIPDHJ_01271 1e-87 uspA T universal stress protein
HPLIPDHJ_01272 3.4e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
HPLIPDHJ_01273 1e-128 XK27_08440 K UTRA domain
HPLIPDHJ_01274 1e-99 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HPLIPDHJ_01275 4.8e-87 ntd 2.4.2.6 F Nucleoside
HPLIPDHJ_01276 7.4e-193 S zinc-ribbon domain
HPLIPDHJ_01277 1.9e-65 2.7.1.191 G PTS system fructose IIA component
HPLIPDHJ_01278 7.1e-147 manZ_1 G PTS system mannose/fructose/sorbose family IID component
HPLIPDHJ_01279 3.4e-129 XK27_08455 G PTS system sorbose-specific iic component
HPLIPDHJ_01280 2.5e-83 2.7.1.191 G PTS system sorbose subfamily IIB component
HPLIPDHJ_01281 5.8e-227 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HPLIPDHJ_01282 1.1e-212 agaS G SIS domain
HPLIPDHJ_01283 2e-124 XK27_08435 K UTRA
HPLIPDHJ_01284 0.0 G Belongs to the glycosyl hydrolase 31 family
HPLIPDHJ_01285 8.7e-153 I alpha/beta hydrolase fold
HPLIPDHJ_01286 8.5e-118 yibF S overlaps another CDS with the same product name
HPLIPDHJ_01287 8.9e-169 yibE S overlaps another CDS with the same product name
HPLIPDHJ_01288 1.6e-264 yjcE P Sodium proton antiporter
HPLIPDHJ_01289 5.8e-76
HPLIPDHJ_01290 3.1e-206 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HPLIPDHJ_01291 5e-263 S Cysteine-rich secretory protein family
HPLIPDHJ_01292 4.6e-125
HPLIPDHJ_01293 4.2e-113 luxT K Bacterial regulatory proteins, tetR family
HPLIPDHJ_01294 2.8e-233 cycA E Amino acid permease
HPLIPDHJ_01295 2.7e-180 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HPLIPDHJ_01296 7e-62
HPLIPDHJ_01297 3.4e-123 S Alpha/beta hydrolase family
HPLIPDHJ_01298 1.7e-151 epsV 2.7.8.12 S glycosyl transferase family 2
HPLIPDHJ_01299 1.2e-156 ypuA S Protein of unknown function (DUF1002)
HPLIPDHJ_01301 9.2e-138 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HPLIPDHJ_01302 8.6e-173 S Alpha/beta hydrolase of unknown function (DUF915)
HPLIPDHJ_01303 2.4e-122 yugP S Putative neutral zinc metallopeptidase
HPLIPDHJ_01304 1.7e-284 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HPLIPDHJ_01305 2.6e-80
HPLIPDHJ_01306 4.3e-132 cobB K SIR2 family
HPLIPDHJ_01307 1.9e-84 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
HPLIPDHJ_01308 3.1e-123 terC P Integral membrane protein TerC family
HPLIPDHJ_01309 4.5e-61 yeaO S Protein of unknown function, DUF488
HPLIPDHJ_01310 4.2e-115 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HPLIPDHJ_01311 1.1e-295 glnP P ABC transporter permease
HPLIPDHJ_01312 2.1e-137 glnQ E ABC transporter, ATP-binding protein
HPLIPDHJ_01313 3e-19
HPLIPDHJ_01314 4.1e-161 L HNH nucleases
HPLIPDHJ_01315 4.5e-120 yfbR S HD containing hydrolase-like enzyme
HPLIPDHJ_01316 6.5e-199 G Glycosyl hydrolases family 8
HPLIPDHJ_01317 8.8e-240 ydaM M Glycosyl transferase
HPLIPDHJ_01319 8e-101
HPLIPDHJ_01320 1.7e-16
HPLIPDHJ_01321 1e-64 S Iron-sulphur cluster biosynthesis
HPLIPDHJ_01322 1.1e-179 ybiR P Citrate transporter
HPLIPDHJ_01323 1.6e-89 lemA S LemA family
HPLIPDHJ_01324 3.5e-150 htpX O Belongs to the peptidase M48B family
HPLIPDHJ_01325 3e-162 K helix_turn_helix, arabinose operon control protein
HPLIPDHJ_01326 5.1e-96 S ABC-type cobalt transport system, permease component
HPLIPDHJ_01327 1.8e-243 cbiO1 S ABC transporter, ATP-binding protein
HPLIPDHJ_01328 4e-108 P Cobalt transport protein
HPLIPDHJ_01329 1.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HPLIPDHJ_01330 3.5e-174 htrA 3.4.21.107 O serine protease
HPLIPDHJ_01331 1.5e-146 vicX 3.1.26.11 S domain protein
HPLIPDHJ_01332 2.2e-143 yycI S YycH protein
HPLIPDHJ_01333 1.2e-244 yycH S YycH protein
HPLIPDHJ_01334 0.0 vicK 2.7.13.3 T Histidine kinase
HPLIPDHJ_01335 2.6e-129 K response regulator
HPLIPDHJ_01338 3e-147 arbV 2.3.1.51 I Acyl-transferase
HPLIPDHJ_01339 1.6e-154 arbx M Glycosyl transferase family 8
HPLIPDHJ_01340 1.9e-183 arbY M Glycosyl transferase family 8
HPLIPDHJ_01341 1.4e-186 arbY M Glycosyl transferase family 8
HPLIPDHJ_01342 1.5e-163 arbZ I Phosphate acyltransferases
HPLIPDHJ_01343 9.3e-86 yhjX_2 P Major Facilitator Superfamily
HPLIPDHJ_01344 4.2e-44 yhjX_2 P Major Facilitator Superfamily
HPLIPDHJ_01345 9.3e-90 yhjX_2 P Major Facilitator Superfamily
HPLIPDHJ_01346 6.7e-243 yhjX_2 P Major Facilitator Superfamily
HPLIPDHJ_01347 2.7e-182 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HPLIPDHJ_01348 5.1e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HPLIPDHJ_01349 4.3e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HPLIPDHJ_01350 1.7e-238 brnQ U Component of the transport system for branched-chain amino acids
HPLIPDHJ_01351 0.0 1.3.5.4 C FAD binding domain
HPLIPDHJ_01352 7.5e-169 K LysR substrate binding domain
HPLIPDHJ_01353 1.3e-279 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HPLIPDHJ_01354 3.7e-187 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HPLIPDHJ_01355 9.9e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HPLIPDHJ_01356 3.1e-248 G Major Facilitator
HPLIPDHJ_01357 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
HPLIPDHJ_01358 9.2e-34 lysR5 K LysR substrate binding domain
HPLIPDHJ_01359 7.3e-56 lysR5 K LysR substrate binding domain
HPLIPDHJ_01361 9.7e-222 sip L Belongs to the 'phage' integrase family
HPLIPDHJ_01362 1.7e-37 M Host cell surface-exposed lipoprotein
HPLIPDHJ_01363 1.8e-95 S Membrane
HPLIPDHJ_01364 3.9e-142 S Domain of unknown function DUF1829
HPLIPDHJ_01365 4.1e-80
HPLIPDHJ_01366 1.8e-77 S Pfam:Peptidase_M78
HPLIPDHJ_01367 6.9e-43 ansR 3.4.21.88 K sequence-specific DNA binding
HPLIPDHJ_01368 2.9e-17 K Helix-turn-helix XRE-family like proteins
HPLIPDHJ_01369 2.9e-139 K Phage antirepressor protein
HPLIPDHJ_01371 1.4e-41
HPLIPDHJ_01372 4.6e-29 K Cro/C1-type HTH DNA-binding domain
HPLIPDHJ_01374 9.7e-32
HPLIPDHJ_01375 1.4e-19
HPLIPDHJ_01376 8.4e-25
HPLIPDHJ_01377 3.7e-34 S Siphovirus Gp157
HPLIPDHJ_01378 3e-45 S Protein of unknown function (DUF1071)
HPLIPDHJ_01379 8.9e-43 S calcium ion binding
HPLIPDHJ_01380 6.9e-62 S IstB-like ATP binding protein
HPLIPDHJ_01383 3.5e-66 S Endodeoxyribonuclease RusA
HPLIPDHJ_01385 3.6e-13
HPLIPDHJ_01387 1.5e-18
HPLIPDHJ_01389 2.4e-70 S Psort location Cytoplasmic, score 8.87
HPLIPDHJ_01391 2.6e-128 xtmA L Terminase small subunit
HPLIPDHJ_01392 8.5e-248 S Terminase-like family
HPLIPDHJ_01393 1.7e-247 S Phage portal protein, SPP1 Gp6-like
HPLIPDHJ_01394 2e-152 S Phage Mu protein F like protein
HPLIPDHJ_01396 1.1e-73 S Domain of unknown function (DUF4355)
HPLIPDHJ_01397 2.3e-60
HPLIPDHJ_01398 1e-193 S Phage major capsid protein E
HPLIPDHJ_01399 8.3e-48
HPLIPDHJ_01400 2.1e-63
HPLIPDHJ_01401 3.1e-98
HPLIPDHJ_01402 1.2e-61
HPLIPDHJ_01403 1.2e-82 S Phage tail tube protein, TTP
HPLIPDHJ_01404 1.1e-66
HPLIPDHJ_01405 5.7e-46
HPLIPDHJ_01406 0.0 M Phage tail tape measure protein TP901
HPLIPDHJ_01407 9.9e-61
HPLIPDHJ_01408 0.0 GT2,GT4 LM gp58-like protein
HPLIPDHJ_01410 3e-38
HPLIPDHJ_01411 1.5e-68
HPLIPDHJ_01412 4.2e-37
HPLIPDHJ_01413 3.6e-07 S Pfam:Phage_holin_6_1
HPLIPDHJ_01414 2.3e-181 lysA2 M Glycosyl hydrolases family 25
HPLIPDHJ_01416 2.2e-102 3.6.1.27 I Acid phosphatase homologues
HPLIPDHJ_01417 6.2e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HPLIPDHJ_01419 6.3e-304 ybiT S ABC transporter, ATP-binding protein
HPLIPDHJ_01420 1.3e-184 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HPLIPDHJ_01421 3.7e-138 F DNA/RNA non-specific endonuclease
HPLIPDHJ_01422 2.8e-154 metQ1 P Belongs to the nlpA lipoprotein family
HPLIPDHJ_01423 1.1e-184 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HPLIPDHJ_01424 1.2e-65 metI P ABC transporter permease
HPLIPDHJ_01425 7.7e-266 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HPLIPDHJ_01426 8.9e-259 frdC 1.3.5.4 C FAD binding domain
HPLIPDHJ_01427 2.2e-168 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HPLIPDHJ_01428 7.5e-242 yjjP S Putative threonine/serine exporter
HPLIPDHJ_01429 4.1e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
HPLIPDHJ_01430 0.0 aha1 P E1-E2 ATPase
HPLIPDHJ_01431 7.2e-303 S Bacterial membrane protein, YfhO
HPLIPDHJ_01432 3.4e-67 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HPLIPDHJ_01433 1.4e-170 prmA J Ribosomal protein L11 methyltransferase
HPLIPDHJ_01434 3e-63
HPLIPDHJ_01435 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HPLIPDHJ_01436 9e-72 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HPLIPDHJ_01437 3.4e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
HPLIPDHJ_01438 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HPLIPDHJ_01439 8.3e-221 patA 2.6.1.1 E Aminotransferase
HPLIPDHJ_01440 1.7e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HPLIPDHJ_01441 2.9e-134 E GDSL-like Lipase/Acylhydrolase family
HPLIPDHJ_01442 9e-101 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HPLIPDHJ_01443 4.5e-155 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HPLIPDHJ_01444 2.1e-120 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HPLIPDHJ_01445 3.6e-152 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HPLIPDHJ_01446 1.9e-50 S Iron-sulfur cluster assembly protein
HPLIPDHJ_01447 2.5e-155 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HPLIPDHJ_01448 1.5e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HPLIPDHJ_01449 2.9e-33 yqeY S YqeY-like protein
HPLIPDHJ_01450 2.2e-171 phoH T phosphate starvation-inducible protein PhoH
HPLIPDHJ_01451 5.7e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HPLIPDHJ_01452 3.6e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HPLIPDHJ_01453 4.9e-134 recO L Involved in DNA repair and RecF pathway recombination
HPLIPDHJ_01454 2.7e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HPLIPDHJ_01455 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HPLIPDHJ_01456 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HPLIPDHJ_01457 1.1e-198 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HPLIPDHJ_01458 2.9e-114 papP P ABC transporter, permease protein
HPLIPDHJ_01459 6.6e-106 P ABC transporter permease
HPLIPDHJ_01460 5.9e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HPLIPDHJ_01461 2.2e-138 cjaA ET ABC transporter substrate-binding protein
HPLIPDHJ_01462 6.7e-117 trmK 2.1.1.217 S SAM-dependent methyltransferase
HPLIPDHJ_01463 6.7e-150 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HPLIPDHJ_01464 8.6e-245 pepT 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HPLIPDHJ_01465 1.1e-57 yvoA_1 K Transcriptional regulator, GntR family
HPLIPDHJ_01466 2.9e-120 skfE V ATPases associated with a variety of cellular activities
HPLIPDHJ_01467 9.6e-144
HPLIPDHJ_01468 8.3e-135
HPLIPDHJ_01469 4.7e-22
HPLIPDHJ_01470 3.1e-101 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HPLIPDHJ_01471 8.6e-128
HPLIPDHJ_01472 1.5e-172
HPLIPDHJ_01473 9.5e-261 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
HPLIPDHJ_01474 1.5e-35 ybjQ S Belongs to the UPF0145 family
HPLIPDHJ_01476 5.6e-132 XK27_05540 S DUF218 domain
HPLIPDHJ_01477 1.9e-144 yxeH S hydrolase
HPLIPDHJ_01478 2.2e-293 I Protein of unknown function (DUF2974)
HPLIPDHJ_01479 1.4e-40 rpmE2 J Ribosomal protein L31
HPLIPDHJ_01480 7.8e-299 ybeC E amino acid
HPLIPDHJ_01481 2.9e-134 XK27_08845 S ABC transporter, ATP-binding protein
HPLIPDHJ_01482 1.6e-139 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HPLIPDHJ_01483 8.9e-176 ABC-SBP S ABC transporter
HPLIPDHJ_01484 3.6e-227 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HPLIPDHJ_01485 2.4e-278 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
HPLIPDHJ_01486 0.0 rafA 3.2.1.22 G alpha-galactosidase
HPLIPDHJ_01487 0.0 gph G Transporter
HPLIPDHJ_01488 6.1e-154 msmR K AraC-like ligand binding domain
HPLIPDHJ_01489 2.6e-282 pipD E Dipeptidase
HPLIPDHJ_01490 1.6e-140 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HPLIPDHJ_01491 3.8e-81 XK27_02070 S Nitroreductase family
HPLIPDHJ_01492 8.7e-32 hxlR K Transcriptional regulator, HxlR family
HPLIPDHJ_01493 4.1e-34
HPLIPDHJ_01494 8.9e-23
HPLIPDHJ_01495 3.6e-62 S Putative adhesin
HPLIPDHJ_01496 1.6e-34
HPLIPDHJ_01497 5.4e-188 yfdV S Membrane transport protein
HPLIPDHJ_01498 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HPLIPDHJ_01499 4.5e-263 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HPLIPDHJ_01500 4e-95
HPLIPDHJ_01501 3.5e-67 adk 2.7.4.3 F adenylate kinase activity
HPLIPDHJ_01502 1.5e-72 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HPLIPDHJ_01503 1.9e-104 lmrB P Belongs to the major facilitator superfamily
HPLIPDHJ_01504 1.2e-102 S B3 4 domain
HPLIPDHJ_01505 8.9e-84 XK27_09675 K Acetyltransferase (GNAT) domain
HPLIPDHJ_01506 3.2e-161 ywhK S Membrane
HPLIPDHJ_01507 5.7e-94 yxkA S Phosphatidylethanolamine-binding protein
HPLIPDHJ_01508 1.9e-102 K transcriptional regulator
HPLIPDHJ_01509 1.4e-12
HPLIPDHJ_01510 3.9e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HPLIPDHJ_01511 3.6e-54 K Psort location CytoplasmicMembrane, score
HPLIPDHJ_01512 9.9e-103 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HPLIPDHJ_01513 1.7e-235 pbuX F xanthine permease
HPLIPDHJ_01514 9.4e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HPLIPDHJ_01515 5.8e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HPLIPDHJ_01516 5.5e-63 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HPLIPDHJ_01517 6.2e-73 S Domain of unknown function (DUF1934)
HPLIPDHJ_01518 8.8e-267 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
HPLIPDHJ_01519 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
HPLIPDHJ_01520 4.1e-153 malG P ABC transporter permease
HPLIPDHJ_01521 2.5e-253 malF P Binding-protein-dependent transport system inner membrane component
HPLIPDHJ_01522 1.8e-215 malE G Bacterial extracellular solute-binding protein
HPLIPDHJ_01523 8e-210 msmX P Belongs to the ABC transporter superfamily
HPLIPDHJ_01524 2.9e-114 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HPLIPDHJ_01525 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HPLIPDHJ_01526 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HPLIPDHJ_01527 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
HPLIPDHJ_01528 1.5e-172 yvdE K helix_turn _helix lactose operon repressor
HPLIPDHJ_01529 7.6e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HPLIPDHJ_01530 8.5e-217 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HPLIPDHJ_01531 1.3e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HPLIPDHJ_01532 2.2e-35 veg S Biofilm formation stimulator VEG
HPLIPDHJ_01533 7.4e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HPLIPDHJ_01534 1.4e-96 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HPLIPDHJ_01535 6.3e-145 tatD L hydrolase, TatD family
HPLIPDHJ_01536 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HPLIPDHJ_01537 2.6e-178 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HPLIPDHJ_01538 3.4e-98 S TPM domain
HPLIPDHJ_01539 5.6e-91 comEB 3.5.4.12 F MafB19-like deaminase
HPLIPDHJ_01540 1.2e-194 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HPLIPDHJ_01541 3.5e-114 E Belongs to the SOS response-associated peptidase family
HPLIPDHJ_01543 5.8e-115
HPLIPDHJ_01544 3.4e-155 ypbG 2.7.1.2 GK ROK family
HPLIPDHJ_01545 5.7e-274 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HPLIPDHJ_01546 1.1e-53 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPLIPDHJ_01547 4.9e-28 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPLIPDHJ_01548 1.3e-24 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPLIPDHJ_01549 1.1e-76 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPLIPDHJ_01550 5.8e-52 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HPLIPDHJ_01551 9e-36
HPLIPDHJ_01552 8.5e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
HPLIPDHJ_01553 4.4e-132 gmuR K UTRA
HPLIPDHJ_01554 2.5e-299 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HPLIPDHJ_01555 9.8e-42 S Domain of unknown function (DUF3284)
HPLIPDHJ_01556 9.1e-127 yydK K UTRA
HPLIPDHJ_01557 1.1e-240 celD 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPLIPDHJ_01558 8.3e-82
HPLIPDHJ_01559 3.2e-291 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HPLIPDHJ_01560 5.6e-77 hsp O Belongs to the small heat shock protein (HSP20) family
HPLIPDHJ_01561 4.1e-75 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HPLIPDHJ_01562 2.6e-32
HPLIPDHJ_01563 2.4e-253 pepC 3.4.22.40 E aminopeptidase
HPLIPDHJ_01564 1.9e-41 ps301 K sequence-specific DNA binding
HPLIPDHJ_01565 4.8e-29 S Motility quorum-sensing regulator, toxin of MqsA
HPLIPDHJ_01566 3.3e-118 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HPLIPDHJ_01567 2e-255 pepC 3.4.22.40 E aminopeptidase
HPLIPDHJ_01569 4.2e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HPLIPDHJ_01570 0.0 XK27_08315 M Sulfatase
HPLIPDHJ_01571 2.5e-112 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HPLIPDHJ_01572 5.2e-193 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HPLIPDHJ_01573 1.6e-168 yqhA G Aldose 1-epimerase
HPLIPDHJ_01574 2.9e-151 glcU U sugar transport
HPLIPDHJ_01575 8.7e-117
HPLIPDHJ_01576 5.7e-99 lmrB EGP Major facilitator Superfamily
HPLIPDHJ_01577 6.3e-10 lmrB EGP Major facilitator Superfamily
HPLIPDHJ_01578 2.8e-12 lmrB EGP Major facilitator Superfamily
HPLIPDHJ_01579 1.2e-177 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HPLIPDHJ_01580 3.4e-71 2.4.1.83 GT2 S GtrA-like protein
HPLIPDHJ_01581 1.7e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HPLIPDHJ_01582 1.6e-249 L transposase, IS605 OrfB family
HPLIPDHJ_01583 2.9e-84 tlpA2 L Transposase IS200 like
HPLIPDHJ_01584 4.6e-11
HPLIPDHJ_01585 8.9e-13
HPLIPDHJ_01588 5.6e-49 S HicB_like antitoxin of bacterial toxin-antitoxin system
HPLIPDHJ_01590 1.1e-132 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HPLIPDHJ_01591 6.6e-72 S PAS domain
HPLIPDHJ_01592 2e-141
HPLIPDHJ_01593 2.7e-135
HPLIPDHJ_01594 1.8e-173 S Oxidoreductase family, NAD-binding Rossmann fold
HPLIPDHJ_01595 0.0 yjbQ P TrkA C-terminal domain protein
HPLIPDHJ_01596 6.8e-142 fruK 2.7.1.11, 2.7.1.56 G pfkB family carbohydrate kinase
HPLIPDHJ_01597 5.3e-39 lysA2 M Glycosyl hydrolases family 25
HPLIPDHJ_01602 1.7e-213 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HPLIPDHJ_01603 2.7e-258 qacA EGP Major facilitator Superfamily
HPLIPDHJ_01604 2e-112 3.6.1.27 I Acid phosphatase homologues
HPLIPDHJ_01605 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HPLIPDHJ_01606 1.6e-299 ytgP S Polysaccharide biosynthesis protein
HPLIPDHJ_01607 2.5e-31 MA20_36090 S Protein of unknown function (DUF2974)
HPLIPDHJ_01608 9.9e-129 MA20_36090 S Protein of unknown function (DUF2974)
HPLIPDHJ_01609 1.1e-135
HPLIPDHJ_01610 7.4e-147 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HPLIPDHJ_01611 2.7e-166 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HPLIPDHJ_01612 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HPLIPDHJ_01613 5e-173 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HPLIPDHJ_01614 1.9e-44
HPLIPDHJ_01615 7.5e-60 K Sigma-54 interaction domain
HPLIPDHJ_01616 1.9e-228 K Sigma-54 interaction domain
HPLIPDHJ_01617 1.5e-55 2.7.1.191 G PTS system fructose IIA component
HPLIPDHJ_01618 8.4e-80 ptsB 2.7.1.191 G PTS system sorbose subfamily IIB component
HPLIPDHJ_01619 2.5e-51 ptsC G PTS system sorbose-specific iic component
HPLIPDHJ_01620 1.4e-54 ptsC G PTS system sorbose-specific iic component
HPLIPDHJ_01621 6.3e-32 ptsD G PTS system mannose/fructose/sorbose family IID component
HPLIPDHJ_01622 2.4e-81 ptsD G PTS system mannose/fructose/sorbose family IID component
HPLIPDHJ_01623 2.7e-44 mgtC S MgtC family
HPLIPDHJ_01624 1.7e-46 mgtC S MgtC family
HPLIPDHJ_01625 8.9e-51 K Sigma-54 factor, core binding domain
HPLIPDHJ_01627 1.2e-91 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HPLIPDHJ_01628 5.9e-123 yfeJ 6.3.5.2 F Glutamine amidotransferase class-I
HPLIPDHJ_01629 2e-92 ylbE GM NAD(P)H-binding
HPLIPDHJ_01630 1.8e-78 yebR 1.8.4.14 T GAF domain-containing protein
HPLIPDHJ_01631 9e-105 yfeO P Voltage gated chloride channel
HPLIPDHJ_01632 1.6e-89 yfeO P Voltage gated chloride channel
HPLIPDHJ_01633 3.4e-191 S Bacteriocin helveticin-J
HPLIPDHJ_01634 4.2e-98 tag 3.2.2.20 L glycosylase
HPLIPDHJ_01635 1.9e-159 mleP3 S Membrane transport protein
HPLIPDHJ_01636 4e-105 S CAAX amino terminal protease
HPLIPDHJ_01637 6.3e-142 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HPLIPDHJ_01638 5.1e-252 emrY EGP Major facilitator Superfamily
HPLIPDHJ_01639 2.8e-255 emrY EGP Major facilitator Superfamily
HPLIPDHJ_01640 8.5e-75 2.3.1.128 K acetyltransferase
HPLIPDHJ_01641 5.6e-141 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HPLIPDHJ_01642 6.6e-101 yagU S Protein of unknown function (DUF1440)
HPLIPDHJ_01643 1.2e-146 S hydrolase
HPLIPDHJ_01644 9.8e-152 K Transcriptional regulator
HPLIPDHJ_01645 3e-29
HPLIPDHJ_01646 7.9e-25
HPLIPDHJ_01647 1.6e-241 pyrP F Permease
HPLIPDHJ_01648 6e-132 lacR K DeoR C terminal sensor domain
HPLIPDHJ_01649 5.1e-72 lacA 5.3.1.26 G Ribose/Galactose Isomerase
HPLIPDHJ_01650 2.4e-104 rpiB 2.1.1.222, 2.1.1.64, 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
HPLIPDHJ_01651 1.6e-120 S Domain of unknown function (DUF4867)
HPLIPDHJ_01652 1.1e-83 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HPLIPDHJ_01653 1.4e-50 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
HPLIPDHJ_01654 2.2e-265 gatC G PTS system sugar-specific permease component
HPLIPDHJ_01655 8.3e-38
HPLIPDHJ_01656 3.5e-133 lacT K CAT RNA binding domain
HPLIPDHJ_01657 6.9e-54 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
HPLIPDHJ_01658 1e-299 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
HPLIPDHJ_01659 1.2e-277 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
HPLIPDHJ_01660 8.8e-170 glsA 3.5.1.2 E Belongs to the glutaminase family
HPLIPDHJ_01661 2.8e-111 3.6.1.27 I Acid phosphatase homologues
HPLIPDHJ_01662 3.9e-283 E Phospholipase B
HPLIPDHJ_01663 3.1e-240 pepC 3.4.22.40 E Peptidase C1-like family
HPLIPDHJ_01664 1.7e-191 gadC E Contains amino acid permease domain
HPLIPDHJ_01666 2.6e-209 yagE E amino acid
HPLIPDHJ_01667 8.2e-216 mdtG EGP Major facilitator Superfamily
HPLIPDHJ_01668 2.3e-69 K helix_turn_helix multiple antibiotic resistance protein
HPLIPDHJ_01669 1.2e-76
HPLIPDHJ_01670 7.3e-208 pepA E M42 glutamyl aminopeptidase
HPLIPDHJ_01672 4.5e-112 ybbL S ABC transporter, ATP-binding protein
HPLIPDHJ_01673 8.1e-129 ybbM S Uncharacterised protein family (UPF0014)
HPLIPDHJ_01674 4.6e-35 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
HPLIPDHJ_01675 4.6e-46 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
HPLIPDHJ_01676 2.3e-119 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
HPLIPDHJ_01677 4.4e-70 lacA 3.2.1.23 G -beta-galactosidase
HPLIPDHJ_01678 1.2e-157 lacA 3.2.1.23 G -beta-galactosidase
HPLIPDHJ_01679 1.9e-44 lacA 3.2.1.23 G -beta-galactosidase
HPLIPDHJ_01680 3e-84 2.7.1.191 G PTS system sorbose subfamily IIB component
HPLIPDHJ_01681 1.8e-107 G PTS system sorbose-specific iic component
HPLIPDHJ_01682 1.6e-149 G PTS system mannose/fructose/sorbose family IID component
HPLIPDHJ_01683 2.5e-66 2.7.1.191 G PTS system fructose IIA component
HPLIPDHJ_01684 3.3e-308 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HPLIPDHJ_01685 3.3e-175 lacI3 K helix_turn _helix lactose operon repressor
HPLIPDHJ_01686 1.1e-281 dtpT U amino acid peptide transporter
HPLIPDHJ_01687 9.5e-37 pipD E Peptidase family C69
HPLIPDHJ_01688 2.1e-39 pipD E Peptidase family C69
HPLIPDHJ_01689 4.2e-56 pipD E Peptidase family C69
HPLIPDHJ_01690 3.4e-217 naiP EGP Major facilitator Superfamily
HPLIPDHJ_01691 1.3e-36 S Alpha beta hydrolase
HPLIPDHJ_01692 1.1e-74 S Alpha beta hydrolase
HPLIPDHJ_01693 6.7e-67 K Transcriptional regulator, MarR family
HPLIPDHJ_01694 7.9e-297 XK27_09600 V ABC transporter, ATP-binding protein
HPLIPDHJ_01695 0.0 V ABC transporter transmembrane region
HPLIPDHJ_01696 1.5e-144 glnH ET ABC transporter
HPLIPDHJ_01697 7.5e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HPLIPDHJ_01698 5.3e-150 glnH ET ABC transporter
HPLIPDHJ_01699 2.4e-110 gluC P ABC transporter permease
HPLIPDHJ_01700 5.7e-107 glnP P ABC transporter permease
HPLIPDHJ_01701 7.2e-65
HPLIPDHJ_01702 2.5e-218 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HPLIPDHJ_01703 1.5e-100 J Acetyltransferase (GNAT) domain
HPLIPDHJ_01704 5.3e-107 yjbF S SNARE associated Golgi protein
HPLIPDHJ_01705 5.9e-154 I alpha/beta hydrolase fold
HPLIPDHJ_01706 4e-153 hipB K Helix-turn-helix
HPLIPDHJ_01707 1.2e-258 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HPLIPDHJ_01708 2.8e-177
HPLIPDHJ_01709 2.2e-125 S SNARE associated Golgi protein
HPLIPDHJ_01710 5.7e-141 cof S haloacid dehalogenase-like hydrolase
HPLIPDHJ_01711 0.0 ydgH S MMPL family
HPLIPDHJ_01712 2.3e-96 yobS K Bacterial regulatory proteins, tetR family
HPLIPDHJ_01713 3.2e-159 3.5.2.6 V Beta-lactamase enzyme family
HPLIPDHJ_01714 2e-166 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
HPLIPDHJ_01715 6.5e-78 yjcF S Acetyltransferase (GNAT) domain
HPLIPDHJ_01716 2.6e-86 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HPLIPDHJ_01717 7e-75 yybA 2.3.1.57 K Transcriptional regulator
HPLIPDHJ_01718 2e-40 ypaA S Protein of unknown function (DUF1304)
HPLIPDHJ_01719 8.2e-238 G Bacterial extracellular solute-binding protein
HPLIPDHJ_01720 1.1e-247 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
HPLIPDHJ_01721 5e-148 gtsC P Binding-protein-dependent transport system inner membrane component
HPLIPDHJ_01722 1e-156 gtsB P ABC-type sugar transport systems, permease components
HPLIPDHJ_01723 4.6e-202 malK P ATPases associated with a variety of cellular activities
HPLIPDHJ_01724 3e-281 pipD E Dipeptidase
HPLIPDHJ_01725 3.9e-156 endA F DNA RNA non-specific endonuclease
HPLIPDHJ_01726 1e-156 dkg S reductase
HPLIPDHJ_01727 8.9e-79 ltrA S Bacterial low temperature requirement A protein (LtrA)
HPLIPDHJ_01728 1e-181 dnaQ 2.7.7.7 L EXOIII
HPLIPDHJ_01729 6.3e-148 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HPLIPDHJ_01730 1.4e-110 yviA S Protein of unknown function (DUF421)
HPLIPDHJ_01731 2.9e-73 S Protein of unknown function (DUF3290)
HPLIPDHJ_01732 7.2e-239 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HPLIPDHJ_01733 9.6e-92 S PAS domain
HPLIPDHJ_01734 1e-142 pnuC H nicotinamide mononucleotide transporter
HPLIPDHJ_01735 5.4e-41 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HPLIPDHJ_01736 2.4e-133 S PAS domain
HPLIPDHJ_01737 1.8e-235 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HPLIPDHJ_01738 5.6e-203 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
HPLIPDHJ_01739 1.5e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HPLIPDHJ_01740 3.2e-60
HPLIPDHJ_01741 2.2e-145 G PTS system mannose/fructose/sorbose family IID component
HPLIPDHJ_01742 1.2e-138 G PTS system sorbose-specific iic component
HPLIPDHJ_01743 5.2e-162 2.7.1.191 G PTS system sorbose subfamily IIB component
HPLIPDHJ_01744 0.0 oppA E ABC transporter substrate-binding protein
HPLIPDHJ_01745 3.9e-154 EG EamA-like transporter family
HPLIPDHJ_01746 8.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HPLIPDHJ_01747 1.9e-163 coaA 2.7.1.33 F Pantothenic acid kinase
HPLIPDHJ_01748 8e-105 E GDSL-like Lipase/Acylhydrolase
HPLIPDHJ_01749 1.9e-237 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPLIPDHJ_01750 4.5e-83 rarA L MgsA AAA+ ATPase C terminal
HPLIPDHJ_01751 1.5e-118 K Helix-turn-helix domain, rpiR family
HPLIPDHJ_01752 5.4e-122 yvpB S Peptidase_C39 like family
HPLIPDHJ_01753 0.0 helD 3.6.4.12 L DNA helicase
HPLIPDHJ_01754 1.9e-115 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HPLIPDHJ_01756 0.0 3.6.3.8 P ATPase, P-type (transporting), HAD superfamily, subfamily IC
HPLIPDHJ_01757 9e-142 rpiR1 K Helix-turn-helix domain, rpiR family
HPLIPDHJ_01758 3.1e-127 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HPLIPDHJ_01759 0.0 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
HPLIPDHJ_01760 9.6e-100 xth 3.1.11.2 L exodeoxyribonuclease III
HPLIPDHJ_01761 9.8e-24 xth 3.1.11.2 L exodeoxyribonuclease III
HPLIPDHJ_01762 1.4e-51
HPLIPDHJ_01763 8.2e-26
HPLIPDHJ_01764 1.4e-124 pgm3 G Phosphoglycerate mutase family
HPLIPDHJ_01765 5.2e-82 gcd E Alcohol dehydrogenase GroES-like domain
HPLIPDHJ_01766 3.3e-16 K transcriptional regulator
HPLIPDHJ_01767 0.0 V FtsX-like permease family
HPLIPDHJ_01768 6.5e-131 cysA V ABC transporter, ATP-binding protein
HPLIPDHJ_01769 5.5e-275 E amino acid
HPLIPDHJ_01770 2.1e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HPLIPDHJ_01771 4.5e-230 S Putative peptidoglycan binding domain
HPLIPDHJ_01772 5.9e-117 M NlpC P60 family protein
HPLIPDHJ_01773 1.4e-98 gmk2 2.7.4.8 F Guanylate kinase
HPLIPDHJ_01774 5.3e-44
HPLIPDHJ_01775 7.3e-262 S O-antigen ligase like membrane protein
HPLIPDHJ_01776 5.3e-110
HPLIPDHJ_01777 3.7e-76 nrdI F Belongs to the NrdI family
HPLIPDHJ_01778 3.9e-173 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HPLIPDHJ_01779 2.6e-80
HPLIPDHJ_01780 2.3e-59 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HPLIPDHJ_01781 1.2e-39
HPLIPDHJ_01782 7e-78 S Threonine/Serine exporter, ThrE
HPLIPDHJ_01783 1.9e-136 thrE S Putative threonine/serine exporter
HPLIPDHJ_01784 4.9e-282 S ABC transporter
HPLIPDHJ_01785 1.1e-60
HPLIPDHJ_01786 5.3e-38
HPLIPDHJ_01787 4.9e-207 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HPLIPDHJ_01788 0.0 pepF E oligoendopeptidase F

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)