ORF_ID e_value Gene_name EC_number CAZy COGs Description
KOEHKIND_00001 4.6e-207 pldB 3.1.1.5 I Serine aminopeptidase, S33
KOEHKIND_00002 7.4e-159 yicL EG EamA-like transporter family
KOEHKIND_00003 3.4e-103
KOEHKIND_00005 3.5e-196 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KOEHKIND_00007 0.0 KL Domain of unknown function (DUF3427)
KOEHKIND_00008 3e-90 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
KOEHKIND_00009 1.1e-36 D DivIVA domain protein
KOEHKIND_00010 9.3e-53 ybjQ S Putative heavy-metal-binding
KOEHKIND_00011 3.1e-158 I Serine aminopeptidase, S33
KOEHKIND_00012 2.2e-87 yjcF Q Acetyltransferase (GNAT) domain
KOEHKIND_00014 1.1e-258 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KOEHKIND_00015 1.7e-244 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
KOEHKIND_00016 0.0 cadA P E1-E2 ATPase
KOEHKIND_00017 2.5e-272 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
KOEHKIND_00018 3.9e-173 htpX O Belongs to the peptidase M48B family
KOEHKIND_00020 0.0 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
KOEHKIND_00021 2.9e-43 S Bacterial mobilisation protein (MobC)
KOEHKIND_00022 2.3e-127 S Domain of unknown function (DUF4417)
KOEHKIND_00024 1.9e-61
KOEHKIND_00025 6.8e-65
KOEHKIND_00026 3.9e-50 E IrrE N-terminal-like domain
KOEHKIND_00027 2e-12 E IrrE N-terminal-like domain
KOEHKIND_00028 4.9e-57 K Cro/C1-type HTH DNA-binding domain
KOEHKIND_00029 4.5e-252 3.5.1.104 G Polysaccharide deacetylase
KOEHKIND_00030 3.3e-200 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
KOEHKIND_00031 1.7e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KOEHKIND_00032 2.5e-164 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KOEHKIND_00033 1.1e-59 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KOEHKIND_00034 2.5e-189 K helix_turn _helix lactose operon repressor
KOEHKIND_00035 1.5e-74 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
KOEHKIND_00036 4.5e-297 scrT G Transporter major facilitator family protein
KOEHKIND_00037 5e-254 yhjE EGP Sugar (and other) transporter
KOEHKIND_00038 2.8e-204 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KOEHKIND_00039 2.7e-199 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KOEHKIND_00040 3.7e-182 gmk 1.1.1.23, 2.7.4.8 S Protein of unknown function (DUF559)
KOEHKIND_00041 0.0 lacZ 3.2.1.23 G Psort location Cytoplasmic, score 8.87
KOEHKIND_00042 2.8e-274 aroP E aromatic amino acid transport protein AroP K03293
KOEHKIND_00043 1e-99 K Transcriptional regulator C-terminal region
KOEHKIND_00044 2.6e-129 V ABC transporter
KOEHKIND_00045 0.0 V FtsX-like permease family
KOEHKIND_00046 8.6e-84 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KOEHKIND_00047 3e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KOEHKIND_00048 1.2e-39 E ABC transporter
KOEHKIND_00049 7.6e-100 bcp 1.11.1.15 O Redoxin
KOEHKIND_00050 1.1e-157 S Virulence factor BrkB
KOEHKIND_00051 2.1e-41 XAC3035 O Glutaredoxin
KOEHKIND_00052 4.8e-48
KOEHKIND_00054 8.1e-99 L Restriction endonuclease NotI
KOEHKIND_00055 1.2e-81
KOEHKIND_00056 0.0 XK27_00515 D Cell surface antigen C-terminus
KOEHKIND_00057 8.9e-26
KOEHKIND_00058 3.3e-139
KOEHKIND_00059 1e-62 S PrgI family protein
KOEHKIND_00060 0.0 trsE U type IV secretory pathway VirB4
KOEHKIND_00061 6.4e-206 isp2 3.2.1.96 M CHAP domain
KOEHKIND_00062 3.6e-14 U Type IV secretory system Conjugative DNA transfer
KOEHKIND_00063 5.1e-119
KOEHKIND_00065 1.1e-100 K Helix-turn-helix domain protein
KOEHKIND_00068 0.0 U Type IV secretory system Conjugative DNA transfer
KOEHKIND_00069 9.3e-31
KOEHKIND_00070 3.2e-39
KOEHKIND_00071 0.0 XK27_00500 KL Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KOEHKIND_00074 2e-275
KOEHKIND_00075 2.5e-168 S Protein of unknown function (DUF3801)
KOEHKIND_00076 4.4e-305 ltrBE1 U Relaxase/Mobilisation nuclease domain
KOEHKIND_00077 4.9e-66 S Bacterial mobilisation protein (MobC)
KOEHKIND_00078 3.6e-41 S Protein of unknown function (DUF2442)
KOEHKIND_00079 8.8e-55
KOEHKIND_00080 1.3e-87
KOEHKIND_00081 0.0 topB 5.99.1.2 L DNA topoisomerase
KOEHKIND_00082 5e-82
KOEHKIND_00083 9.4e-60
KOEHKIND_00084 5.8e-48
KOEHKIND_00085 1e-232 S HipA-like C-terminal domain
KOEHKIND_00086 1.1e-256 S Domain of unknown function (DUF4143)
KOEHKIND_00087 2.3e-57 yccF S Inner membrane component domain
KOEHKIND_00088 4.5e-12
KOEHKIND_00089 0.0 cysB 4.2.1.22 EGP Major facilitator Superfamily
KOEHKIND_00090 1.1e-42 tnp7109-21 L Integrase core domain
KOEHKIND_00091 3.9e-52 L IstB-like ATP binding protein
KOEHKIND_00092 4.7e-84 V ATPases associated with a variety of cellular activities
KOEHKIND_00093 2e-73 I Sterol carrier protein
KOEHKIND_00094 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KOEHKIND_00095 3.4e-35
KOEHKIND_00096 1.4e-144 gluP 3.4.21.105 S Rhomboid family
KOEHKIND_00097 4.7e-257 L ribosomal rna small subunit methyltransferase
KOEHKIND_00098 2.6e-71 crgA D Involved in cell division
KOEHKIND_00099 3.5e-143 S Bacterial protein of unknown function (DUF881)
KOEHKIND_00100 1.7e-232 srtA 3.4.22.70 M Sortase family
KOEHKIND_00101 3.4e-120 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
KOEHKIND_00102 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
KOEHKIND_00103 2e-183 T Protein tyrosine kinase
KOEHKIND_00104 2.8e-263 pbpA M penicillin-binding protein
KOEHKIND_00105 2.8e-266 rodA D Belongs to the SEDS family
KOEHKIND_00106 4.8e-259 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
KOEHKIND_00107 7.9e-94 fhaB T Inner membrane component of T3SS, cytoplasmic domain
KOEHKIND_00108 1e-130 fhaA T Protein of unknown function (DUF2662)
KOEHKIND_00109 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
KOEHKIND_00110 0.0 pip S YhgE Pip domain protein
KOEHKIND_00111 0.0 pip S YhgE Pip domain protein
KOEHKIND_00112 2.1e-34 yhcC S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
KOEHKIND_00113 1.1e-24
KOEHKIND_00114 2.7e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
KOEHKIND_00115 1.7e-104 ypfH S Phospholipase/Carboxylesterase
KOEHKIND_00116 0.0 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
KOEHKIND_00118 1.7e-287 2.4.1.166 GT2 M Glycosyltransferase like family 2
KOEHKIND_00119 8.4e-119 3.1.3.27 E haloacid dehalogenase-like hydrolase
KOEHKIND_00120 1.9e-144 rlrG K Bacterial regulatory helix-turn-helix protein, lysR family
KOEHKIND_00121 3.2e-187 MA20_14895 S Conserved hypothetical protein 698
KOEHKIND_00122 4.2e-63 S Phospholipase/Carboxylesterase
KOEHKIND_00123 1.1e-158 3.1.3.73 G Phosphoglycerate mutase family
KOEHKIND_00124 3.1e-237 rutG F Permease family
KOEHKIND_00125 1.2e-74 K AraC-like ligand binding domain
KOEHKIND_00127 3.7e-51 IQ oxidoreductase activity
KOEHKIND_00128 2.1e-135 ybbM V Uncharacterised protein family (UPF0014)
KOEHKIND_00129 6.9e-136 ybbL V ATPases associated with a variety of cellular activities
KOEHKIND_00130 4.6e-160 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KOEHKIND_00131 3.1e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KOEHKIND_00132 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
KOEHKIND_00133 5.1e-87
KOEHKIND_00134 2.2e-204 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KOEHKIND_00135 1.3e-215 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KOEHKIND_00136 1.7e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
KOEHKIND_00137 1.9e-247 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
KOEHKIND_00138 1.6e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KOEHKIND_00139 1.1e-84 argR K Regulates arginine biosynthesis genes
KOEHKIND_00140 4.1e-239 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KOEHKIND_00141 1.1e-27 3.1.21.3 V type I restriction enzyme
KOEHKIND_00142 1.5e-156 K Putative DNA-binding domain
KOEHKIND_00143 2.2e-105 L transposase activity
KOEHKIND_00144 9.7e-107 L PFAM Integrase catalytic
KOEHKIND_00145 2.5e-155 L Transposase, Mutator family
KOEHKIND_00146 1.2e-168 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KOEHKIND_00147 3.8e-140 rgpC U Transport permease protein
KOEHKIND_00148 1.3e-208 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
KOEHKIND_00149 2.5e-294 S Tetratricopeptide repeat
KOEHKIND_00150 0.0 rgpF M Rhamnan synthesis protein F
KOEHKIND_00151 2.2e-193 M Glycosyltransferase like family 2
KOEHKIND_00152 5.2e-65 S Zincin-like metallopeptidase
KOEHKIND_00153 2.7e-87 S Helix-turn-helix
KOEHKIND_00154 5.4e-197 S Short C-terminal domain
KOEHKIND_00155 2.7e-22
KOEHKIND_00156 1.1e-149
KOEHKIND_00157 2.6e-79 K Psort location Cytoplasmic, score
KOEHKIND_00158 3.7e-259 KLT Protein tyrosine kinase
KOEHKIND_00159 7.9e-66 S Cupin 2, conserved barrel domain protein
KOEHKIND_00160 2.3e-156 ksgA 2.1.1.182 J Methyltransferase domain
KOEHKIND_00161 5.6e-59 yccF S Inner membrane component domain
KOEHKIND_00162 8.6e-120 E Psort location Cytoplasmic, score 8.87
KOEHKIND_00163 7.9e-17 M Belongs to the glycosyl hydrolase 30 family
KOEHKIND_00165 3.8e-152 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KOEHKIND_00166 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KOEHKIND_00167 7.5e-126 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KOEHKIND_00168 1.3e-77 S CRISPR-associated protein (Cas_Csn2)
KOEHKIND_00169 1.2e-155 L Phage integrase family
KOEHKIND_00170 7.8e-131 fic D Fic/DOC family
KOEHKIND_00171 3.3e-26
KOEHKIND_00172 4.3e-27 L DNA integration
KOEHKIND_00173 4.1e-144 L IstB-like ATP binding protein
KOEHKIND_00174 5.8e-296 L PFAM Integrase catalytic
KOEHKIND_00175 1.2e-109 L Transposase and inactivated derivatives IS30 family
KOEHKIND_00176 1.3e-284 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
KOEHKIND_00177 6e-250 V ABC-2 family transporter protein
KOEHKIND_00178 8.1e-227 V ABC-2 family transporter protein
KOEHKIND_00179 6.9e-181 V ATPases associated with a variety of cellular activities
KOEHKIND_00180 1.2e-42 pacL 3.6.3.8, 3.6.3.9 P ATPase, P-type transporting, HAD superfamily, subfamily IC
KOEHKIND_00181 9.2e-234 T Histidine kinase
KOEHKIND_00182 3.1e-119 K helix_turn_helix, Lux Regulon
KOEHKIND_00183 1.1e-115 MA20_27875 P Protein of unknown function DUF47
KOEHKIND_00184 3.4e-189 pit P Phosphate transporter family
KOEHKIND_00185 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
KOEHKIND_00186 1.1e-302 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KOEHKIND_00189 4.4e-51
KOEHKIND_00190 5.1e-45
KOEHKIND_00191 9.9e-112 ysdA S Protein of unknown function (DUF1294)
KOEHKIND_00193 1.7e-122
KOEHKIND_00194 1e-281 XK27_07020 S Domain of unknown function (DUF1846)
KOEHKIND_00195 0.0 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
KOEHKIND_00196 9.8e-233 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KOEHKIND_00197 6.3e-274 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KOEHKIND_00198 2.9e-108 3.4.13.21 E Peptidase family S51
KOEHKIND_00199 4.2e-135 L Phage integrase family
KOEHKIND_00201 1.5e-218 ykiI
KOEHKIND_00202 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
KOEHKIND_00203 1.4e-119 3.6.1.13 L NUDIX domain
KOEHKIND_00204 3.2e-172 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
KOEHKIND_00205 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KOEHKIND_00206 9.2e-120 pdtaR T Response regulator receiver domain protein
KOEHKIND_00208 3.3e-109 aspA 3.6.1.13 L NUDIX domain
KOEHKIND_00209 6.6e-273 pyk 2.7.1.40 G Pyruvate kinase
KOEHKIND_00210 1.3e-179 terC P Integral membrane protein, TerC family
KOEHKIND_00211 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KOEHKIND_00212 4.5e-106 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KOEHKIND_00213 6.8e-241 rpsA J Ribosomal protein S1
KOEHKIND_00214 1.8e-164 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KOEHKIND_00215 3.7e-172 P Zinc-uptake complex component A periplasmic
KOEHKIND_00216 1.8e-164 znuC P ATPases associated with a variety of cellular activities
KOEHKIND_00217 2.5e-131 znuB U ABC 3 transport family
KOEHKIND_00218 8.5e-84 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
KOEHKIND_00219 5.1e-102 carD K CarD-like/TRCF domain
KOEHKIND_00220 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KOEHKIND_00221 1.9e-127 T Response regulator receiver domain protein
KOEHKIND_00222 4.3e-203 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
KOEHKIND_00223 2.1e-72 rulA 3.4.21.88 KT Peptidase S24-like
KOEHKIND_00224 1.4e-130 ctsW S Phosphoribosyl transferase domain
KOEHKIND_00225 3.4e-157 cof 5.2.1.8 T Eukaryotic phosphomannomutase
KOEHKIND_00226 6.3e-66 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
KOEHKIND_00227 3.6e-261
KOEHKIND_00228 0.0 S Glycosyl transferase, family 2
KOEHKIND_00229 5.8e-54 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
KOEHKIND_00230 2.4e-270 K Cell envelope-related transcriptional attenuator domain
KOEHKIND_00231 0.0 D FtsK/SpoIIIE family
KOEHKIND_00232 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
KOEHKIND_00233 1.1e-284 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
KOEHKIND_00234 2e-142 yplQ S Haemolysin-III related
KOEHKIND_00235 2.3e-107
KOEHKIND_00238 7.5e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KOEHKIND_00239 5.7e-73 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
KOEHKIND_00240 2.3e-281 sdaA 4.3.1.17 E Serine dehydratase alpha chain
KOEHKIND_00241 1.6e-97
KOEHKIND_00243 3.6e-185 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
KOEHKIND_00244 2e-106 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
KOEHKIND_00245 4.2e-101 divIC D Septum formation initiator
KOEHKIND_00246 6.9e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KOEHKIND_00247 1.4e-152 pabC 2.6.1.42, 2.6.1.85, 4.1.3.38 E branched-chain-amino-acid transaminase activity
KOEHKIND_00248 5.3e-297 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH chorismate binding enzyme
KOEHKIND_00249 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KOEHKIND_00250 7.6e-114 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KOEHKIND_00251 1.7e-96 2.3.1.183 M Acetyltransferase (GNAT) domain
KOEHKIND_00252 4.9e-145 tagH 3.6.3.38, 3.6.3.40 GM ABC transporter
KOEHKIND_00253 2.3e-150 GM ABC-2 type transporter
KOEHKIND_00254 5.6e-197 GM GDP-mannose 4,6 dehydratase
KOEHKIND_00255 2.6e-129 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KOEHKIND_00257 8.6e-218 I transferase activity, transferring acyl groups other than amino-acyl groups
KOEHKIND_00258 0.0 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KOEHKIND_00259 2.1e-207 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KOEHKIND_00260 0.0 S Uncharacterised protein family (UPF0182)
KOEHKIND_00261 7.4e-231 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
KOEHKIND_00262 2.2e-196
KOEHKIND_00263 4.3e-152 ytrE V ATPases associated with a variety of cellular activities
KOEHKIND_00264 7e-190 V N-Acetylmuramoyl-L-alanine amidase
KOEHKIND_00265 3.4e-258 argE E Peptidase dimerisation domain
KOEHKIND_00266 1.2e-103 S Protein of unknown function (DUF3043)
KOEHKIND_00267 2.9e-279 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KOEHKIND_00268 5.3e-139 S Domain of unknown function (DUF4191)
KOEHKIND_00269 1.8e-286 glnA 6.3.1.2 E glutamine synthetase
KOEHKIND_00270 4.3e-18
KOEHKIND_00272 4.2e-19
KOEHKIND_00276 6.8e-161 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
KOEHKIND_00277 1.6e-210 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
KOEHKIND_00278 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KOEHKIND_00279 0.0 S Tetratricopeptide repeat
KOEHKIND_00280 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KOEHKIND_00281 8.2e-72 2.8.2.22 S Arylsulfotransferase Ig-like domain
KOEHKIND_00282 3.4e-138 bioM P ATPases associated with a variety of cellular activities
KOEHKIND_00283 2e-213 E Aminotransferase class I and II
KOEHKIND_00284 1.7e-139 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
KOEHKIND_00286 1.5e-104 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KOEHKIND_00287 0.0 ecfA GP ABC transporter, ATP-binding protein
KOEHKIND_00288 3.4e-256 EGP Major facilitator Superfamily
KOEHKIND_00290 8.5e-257 rarA L Recombination factor protein RarA
KOEHKIND_00291 0.0 L DEAD DEAH box helicase
KOEHKIND_00292 6e-194 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
KOEHKIND_00293 4.8e-199 gluD E Binding-protein-dependent transport system inner membrane component
KOEHKIND_00294 1.8e-111 gluC E Binding-protein-dependent transport system inner membrane component
KOEHKIND_00295 1.2e-146 gluB ET Belongs to the bacterial solute-binding protein 3 family
KOEHKIND_00296 1e-139 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
KOEHKIND_00297 3.4e-91 S Aminoacyl-tRNA editing domain
KOEHKIND_00298 6e-74 K helix_turn_helix, Lux Regulon
KOEHKIND_00299 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KOEHKIND_00300 7.1e-264 hisS 6.1.1.21 J Histidyl-tRNA synthetase
KOEHKIND_00301 1.5e-216 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
KOEHKIND_00305 0.0 clpC O ATPase family associated with various cellular activities (AAA)
KOEHKIND_00306 3e-184 uspA T Belongs to the universal stress protein A family
KOEHKIND_00307 7.3e-192 S Protein of unknown function (DUF3027)
KOEHKIND_00308 5e-66 cspB K 'Cold-shock' DNA-binding domain
KOEHKIND_00309 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
KOEHKIND_00310 1.6e-134 KT Response regulator receiver domain protein
KOEHKIND_00311 4.9e-162
KOEHKIND_00312 1.7e-10 S Proteins of 100 residues with WXG
KOEHKIND_00313 2.7e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KOEHKIND_00314 2.2e-44 cspA K 'Cold-shock' DNA-binding domain
KOEHKIND_00315 3.4e-71 S LytR cell envelope-related transcriptional attenuator
KOEHKIND_00316 8e-145 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KOEHKIND_00317 5e-196 moxR S ATPase family associated with various cellular activities (AAA)
KOEHKIND_00318 7.2e-178 S Protein of unknown function DUF58
KOEHKIND_00319 6.4e-94
KOEHKIND_00320 2.3e-190 S von Willebrand factor (vWF) type A domain
KOEHKIND_00321 1.6e-148 S von Willebrand factor (vWF) type A domain
KOEHKIND_00322 2.8e-71
KOEHKIND_00324 8.3e-290 S PGAP1-like protein
KOEHKIND_00325 4.7e-279 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
KOEHKIND_00326 0.0 S Lysylphosphatidylglycerol synthase TM region
KOEHKIND_00327 8.1e-42 hup L Belongs to the bacterial histone-like protein family
KOEHKIND_00328 1.4e-275 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
KOEHKIND_00329 9.2e-11 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
KOEHKIND_00330 2.6e-160 hisN 3.1.3.25 G Inositol monophosphatase family
KOEHKIND_00331 0.0 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
KOEHKIND_00332 0.0 arc O AAA ATPase forming ring-shaped complexes
KOEHKIND_00333 2.8e-137 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
KOEHKIND_00334 4.3e-183 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KOEHKIND_00335 3.2e-135 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KOEHKIND_00336 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KOEHKIND_00337 1.9e-220 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KOEHKIND_00338 1.1e-53 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KOEHKIND_00339 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
KOEHKIND_00340 2.5e-166 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
KOEHKIND_00342 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KOEHKIND_00343 0.0 ctpE P E1-E2 ATPase
KOEHKIND_00344 1.2e-109
KOEHKIND_00345 2.9e-248 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KOEHKIND_00346 1.4e-123 S Protein of unknown function (DUF3159)
KOEHKIND_00347 3.2e-139 S Protein of unknown function (DUF3710)
KOEHKIND_00348 1.3e-170 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
KOEHKIND_00349 5.2e-262 pepC 3.4.22.40 E Peptidase C1-like family
KOEHKIND_00350 0.0 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
KOEHKIND_00351 0.0 oppD P Belongs to the ABC transporter superfamily
KOEHKIND_00352 3.5e-166 dppC EP N-terminal TM domain of oligopeptide transport permease C
KOEHKIND_00353 7.9e-177 appB EP Binding-protein-dependent transport system inner membrane component
KOEHKIND_00354 1.3e-187 xerC D Belongs to the 'phage' integrase family. XerC subfamily
KOEHKIND_00355 7.3e-42
KOEHKIND_00356 5.4e-192 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
KOEHKIND_00357 1.2e-196 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
KOEHKIND_00358 3.5e-78
KOEHKIND_00359 0.0 typA T Elongation factor G C-terminus
KOEHKIND_00360 1.3e-235 iscS1 2.8.1.7 E Aminotransferase class-V
KOEHKIND_00361 9.1e-164 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, N-terminal domain
KOEHKIND_00362 0.0 nadB 1.3.5.4, 1.4.3.16, 2.4.2.19 H Catalyzes the oxidation of L-aspartate to iminoaspartate
KOEHKIND_00363 9.8e-252 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KOEHKIND_00364 1.6e-148 nrtR 3.6.1.55 F NUDIX hydrolase
KOEHKIND_00365 1.6e-112 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KOEHKIND_00366 1.2e-149 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KOEHKIND_00367 1.8e-152 soj D CobQ CobB MinD ParA nucleotide binding domain protein
KOEHKIND_00368 2.9e-179 xerD D recombinase XerD
KOEHKIND_00369 9.6e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KOEHKIND_00370 2.1e-25 rpmI J Ribosomal protein L35
KOEHKIND_00371 6.2e-110 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KOEHKIND_00373 2.3e-133 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
KOEHKIND_00374 1e-198 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KOEHKIND_00375 3.2e-99 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KOEHKIND_00376 5.5e-178 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KOEHKIND_00377 5.3e-194 galM 5.1.3.3 G Aldose 1-epimerase
KOEHKIND_00378 5.8e-64
KOEHKIND_00379 7.1e-125 sigH K Belongs to the sigma-70 factor family. ECF subfamily
KOEHKIND_00380 1.3e-296 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KOEHKIND_00381 9.8e-191 V Acetyltransferase (GNAT) domain
KOEHKIND_00382 4.9e-229 2.6.1.33 M DegT/DnrJ/EryC1/StrS aminotransferase family
KOEHKIND_00383 9.5e-244 yxbA 6.3.1.12 S ATP-grasp
KOEHKIND_00384 7.4e-129 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
KOEHKIND_00385 0.0 smc D Required for chromosome condensation and partitioning
KOEHKIND_00386 2e-289 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
KOEHKIND_00388 2.1e-96 3.6.1.55 F NUDIX domain
KOEHKIND_00389 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
KOEHKIND_00390 0.0 P Belongs to the ABC transporter superfamily
KOEHKIND_00391 3.3e-190 dppC EP Binding-protein-dependent transport system inner membrane component
KOEHKIND_00392 2e-184 dppB EP Binding-protein-dependent transport system inner membrane component
KOEHKIND_00393 2.2e-304 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
KOEHKIND_00394 9.6e-244 nagA 3.5.1.25 G Amidohydrolase family
KOEHKIND_00395 6.6e-153 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KOEHKIND_00396 2.6e-216 GK ROK family
KOEHKIND_00397 3.4e-132 cutC P Participates in the control of copper homeostasis
KOEHKIND_00398 1.1e-223 GK ROK family
KOEHKIND_00399 1.9e-169 2.7.1.4 G pfkB family carbohydrate kinase
KOEHKIND_00400 4.4e-236 G Major Facilitator Superfamily
KOEHKIND_00401 6.6e-85 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KOEHKIND_00403 1.3e-37
KOEHKIND_00404 4.7e-158 ftsQ 6.3.2.4 D Cell division protein FtsQ
KOEHKIND_00405 1.8e-295 murC 6.3.2.8 M Belongs to the MurCDEF family
KOEHKIND_00406 1.7e-218 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KOEHKIND_00407 9.6e-226 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
KOEHKIND_00408 1.2e-266 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KOEHKIND_00409 3.6e-202 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KOEHKIND_00410 1.3e-282 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KOEHKIND_00411 2.8e-180 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KOEHKIND_00412 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
KOEHKIND_00413 9.7e-64 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KOEHKIND_00414 1.6e-205 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KOEHKIND_00415 1.3e-90 mraZ K Belongs to the MraZ family
KOEHKIND_00416 0.0 L DNA helicase
KOEHKIND_00417 1.7e-229 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
KOEHKIND_00418 2.3e-83 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KOEHKIND_00419 1.7e-50 M Lysin motif
KOEHKIND_00420 7.5e-129 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KOEHKIND_00421 6e-166 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KOEHKIND_00422 4.6e-177 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
KOEHKIND_00423 2.1e-272 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KOEHKIND_00424 3.9e-173
KOEHKIND_00425 3.1e-121 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
KOEHKIND_00426 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
KOEHKIND_00427 1.2e-154 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
KOEHKIND_00428 2.1e-61 EGP Major facilitator Superfamily
KOEHKIND_00429 1e-251 S Domain of unknown function (DUF5067)
KOEHKIND_00430 2.1e-265 glnA2 6.3.1.2 E glutamine synthetase
KOEHKIND_00431 4.9e-284 S Uncharacterized protein conserved in bacteria (DUF2252)
KOEHKIND_00432 4.9e-131 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
KOEHKIND_00433 1.4e-121 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KOEHKIND_00434 1.7e-112
KOEHKIND_00435 3.2e-112 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
KOEHKIND_00436 2.1e-224 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KOEHKIND_00437 2.1e-255 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KOEHKIND_00438 2.3e-181 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
KOEHKIND_00440 1.2e-76 yneG S Domain of unknown function (DUF4186)
KOEHKIND_00441 6.4e-173 dkgA 1.1.1.346 C Aldo/keto reductase family
KOEHKIND_00442 5e-156 yvgN 1.1.1.346 S Aldo/keto reductase family
KOEHKIND_00443 3.4e-202 K WYL domain
KOEHKIND_00445 0.0 4.2.1.53 S MCRA family
KOEHKIND_00446 2e-46 yhbY J CRS1_YhbY
KOEHKIND_00447 7.6e-106 S zinc-ribbon domain
KOEHKIND_00448 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
KOEHKIND_00449 8.8e-39 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
KOEHKIND_00450 1.7e-15 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
KOEHKIND_00451 5.1e-192 ywqG S Domain of unknown function (DUF1963)
KOEHKIND_00452 1.5e-154 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KOEHKIND_00453 2.3e-142 recO L Involved in DNA repair and RecF pathway recombination
KOEHKIND_00454 5e-293 I acetylesterase activity
KOEHKIND_00455 3.9e-235 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KOEHKIND_00456 3.7e-221 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
KOEHKIND_00457 1.3e-202 2.7.11.1 NU Tfp pilus assembly protein FimV
KOEHKIND_00459 3.3e-23
KOEHKIND_00460 5.7e-19
KOEHKIND_00461 4.9e-150 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
KOEHKIND_00462 3e-76 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KOEHKIND_00463 2.5e-163 usp 3.5.1.28 CBM50 D CHAP domain protein
KOEHKIND_00464 9.2e-159 ftsX D Part of the ABC transporter FtsEX involved in cellular division
KOEHKIND_00465 5.9e-197 ftsE D Cell division ATP-binding protein FtsE
KOEHKIND_00466 8.2e-202 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KOEHKIND_00467 5.2e-147 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
KOEHKIND_00468 6e-63
KOEHKIND_00470 2e-177 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
KOEHKIND_00471 9.9e-102 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KOEHKIND_00472 9.7e-90 3.1.21.3 V DivIVA protein
KOEHKIND_00473 2.1e-42 yggT S YGGT family
KOEHKIND_00474 4.3e-80 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KOEHKIND_00475 7.3e-231 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KOEHKIND_00476 3.6e-246 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KOEHKIND_00477 2.3e-300 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
KOEHKIND_00478 0.0 lacZ 3.2.1.23 G Domain of unknown function (DUF4982)
KOEHKIND_00479 6.1e-160 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KOEHKIND_00480 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KOEHKIND_00481 1.3e-84
KOEHKIND_00482 6.9e-231 O AAA domain (Cdc48 subfamily)
KOEHKIND_00483 2.7e-163 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KOEHKIND_00484 8e-61 S Thiamine-binding protein
KOEHKIND_00485 1.2e-196 K helix_turn _helix lactose operon repressor
KOEHKIND_00486 5.7e-47 S Protein of unknown function (DUF3052)
KOEHKIND_00487 7.6e-152 lon T Belongs to the peptidase S16 family
KOEHKIND_00488 1.8e-284 S Zincin-like metallopeptidase
KOEHKIND_00489 1.5e-280 uvrD2 3.6.4.12 L DNA helicase
KOEHKIND_00490 8.7e-244 mphA S Aminoglycoside phosphotransferase
KOEHKIND_00491 6.1e-32 S Protein of unknown function (DUF3107)
KOEHKIND_00492 1.9e-166 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
KOEHKIND_00493 7.6e-115 S Vitamin K epoxide reductase
KOEHKIND_00494 5.6e-169 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
KOEHKIND_00495 4.6e-154 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KOEHKIND_00496 1.2e-169 S Patatin-like phospholipase
KOEHKIND_00497 0.0 V ABC transporter transmembrane region
KOEHKIND_00498 0.0 V ABC transporter, ATP-binding protein
KOEHKIND_00499 1.1e-90 K MarR family
KOEHKIND_00500 0.0 plyA3 3.2.1.18 GH33 M Parallel beta-helix repeats
KOEHKIND_00501 3.4e-261 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
KOEHKIND_00502 1.9e-164
KOEHKIND_00503 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
KOEHKIND_00505 2.5e-140 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KOEHKIND_00506 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
KOEHKIND_00507 3e-270 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KOEHKIND_00508 2.3e-42 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KOEHKIND_00509 8e-171 S Endonuclease/Exonuclease/phosphatase family
KOEHKIND_00511 4e-181 iunH1 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
KOEHKIND_00512 4.8e-257 cdr OP Sulfurtransferase TusA
KOEHKIND_00513 2.6e-149 moeB 2.7.7.80 H ThiF family
KOEHKIND_00514 5.4e-133 tmp1 S Domain of unknown function (DUF4391)
KOEHKIND_00515 6.9e-157 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
KOEHKIND_00516 2.9e-229 aspB E Aminotransferase class-V
KOEHKIND_00517 2.5e-101 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
KOEHKIND_00518 3.6e-271 S zinc finger
KOEHKIND_00519 1.2e-123 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KOEHKIND_00520 1.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KOEHKIND_00521 2e-204 O Subtilase family
KOEHKIND_00522 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
KOEHKIND_00523 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KOEHKIND_00524 1.9e-161 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KOEHKIND_00525 1e-132 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KOEHKIND_00526 1.4e-59 L Transposase
KOEHKIND_00527 6.4e-24 relB L RelB antitoxin
KOEHKIND_00528 2.7e-10 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
KOEHKIND_00529 6.5e-43 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
KOEHKIND_00530 2.9e-66 gsiA P ATPase activity
KOEHKIND_00531 1.3e-257 G Major Facilitator Superfamily
KOEHKIND_00532 8.6e-159 K -acetyltransferase
KOEHKIND_00533 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
KOEHKIND_00534 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
KOEHKIND_00535 5.2e-270 KLT Protein tyrosine kinase
KOEHKIND_00536 0.0 S Fibronectin type 3 domain
KOEHKIND_00537 3.9e-232 S ATPase family associated with various cellular activities (AAA)
KOEHKIND_00538 1.7e-230 S Protein of unknown function DUF58
KOEHKIND_00539 0.0 E Transglutaminase-like superfamily
KOEHKIND_00540 2e-166 3.1.3.16 T Sigma factor PP2C-like phosphatases
KOEHKIND_00541 2.8e-68 B Belongs to the OprB family
KOEHKIND_00542 7.2e-95 T Forkhead associated domain
KOEHKIND_00543 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KOEHKIND_00544 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KOEHKIND_00545 1.4e-105
KOEHKIND_00546 5.8e-187 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
KOEHKIND_00547 6.3e-51 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G Putative cell wall binding repeat
KOEHKIND_00548 6.3e-122 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KOEHKIND_00550 1.9e-72
KOEHKIND_00551 1e-251 S UPF0210 protein
KOEHKIND_00552 4.2e-43 gcvR T Belongs to the UPF0237 family
KOEHKIND_00553 8.6e-243 EGP Sugar (and other) transporter
KOEHKIND_00554 9.9e-233 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
KOEHKIND_00555 3.3e-252 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
KOEHKIND_00556 3.1e-139 glpR K DeoR C terminal sensor domain
KOEHKIND_00557 6.7e-227 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
KOEHKIND_00558 6.3e-218 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
KOEHKIND_00559 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
KOEHKIND_00560 1.6e-134 glxR K helix_turn_helix, cAMP Regulatory protein
KOEHKIND_00561 5.8e-120 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
KOEHKIND_00562 2.4e-192 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KOEHKIND_00563 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
KOEHKIND_00564 7.7e-239 S Uncharacterized conserved protein (DUF2183)
KOEHKIND_00565 4.9e-72 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
KOEHKIND_00566 0.0 enhA_2 S L,D-transpeptidase catalytic domain
KOEHKIND_00567 3.1e-206 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
KOEHKIND_00568 2.6e-160 mhpC I Alpha/beta hydrolase family
KOEHKIND_00569 4.8e-119 F Domain of unknown function (DUF4916)
KOEHKIND_00570 2.5e-59 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
KOEHKIND_00571 5e-179 S G5
KOEHKIND_00572 2.2e-224
KOEHKIND_00574 4.1e-104 K cell envelope-related transcriptional attenuator
KOEHKIND_00575 1.4e-12 L Transposase
KOEHKIND_00576 3e-43
KOEHKIND_00577 4.4e-91 S Transcription factor WhiB
KOEHKIND_00578 8.2e-117 parA D AAA domain
KOEHKIND_00579 4.8e-156 neo 2.7.1.87, 2.7.1.95 F Phosphotransferase enzyme family
KOEHKIND_00580 7.3e-93
KOEHKIND_00581 1.1e-19
KOEHKIND_00582 1.3e-43 L Integrase core domain
KOEHKIND_00583 6.3e-164 tnp7109-2 L PFAM Transposase, Mutator family
KOEHKIND_00584 5.8e-35 L Psort location Cytoplasmic, score 8.87
KOEHKIND_00585 6e-58 S pathogenesis
KOEHKIND_00586 3.6e-69
KOEHKIND_00589 5.7e-88 topB 5.99.1.2 L DNA topoisomerase
KOEHKIND_00590 2.9e-87 topB 5.99.1.2 L DNA topoisomerase
KOEHKIND_00593 4.9e-85 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
KOEHKIND_00594 1.3e-57 2.7.1.2 GK ROK family
KOEHKIND_00595 4.7e-109 M1-530 S Protein of unknown function (DUF4127)
KOEHKIND_00596 7.1e-94 lacG G Binding-protein-dependent transport system inner membrane component
KOEHKIND_00597 7.7e-144 rfbP 2.7.8.6 M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
KOEHKIND_00598 1.5e-305 EGP Major facilitator Superfamily
KOEHKIND_00599 4.7e-225 mntH P H( )-stimulated, divalent metal cation uptake system
KOEHKIND_00600 2.1e-134 L Protein of unknown function (DUF1524)
KOEHKIND_00601 2.9e-170 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
KOEHKIND_00602 9.3e-11 3.2.1.14 GH18 EM Domain of unknown function (DUF5011)
KOEHKIND_00603 2.1e-202 K helix_turn _helix lactose operon repressor
KOEHKIND_00604 6.5e-107 G Glycosyl hydrolases family 43
KOEHKIND_00605 1.9e-173 G Glycosyl hydrolases family 43
KOEHKIND_00608 1.3e-111 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KOEHKIND_00609 6.9e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KOEHKIND_00610 0.0 fadD 6.2.1.3 I AMP-binding enzyme
KOEHKIND_00611 3e-201 K helix_turn _helix lactose operon repressor
KOEHKIND_00612 2.5e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KOEHKIND_00613 4.4e-157 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KOEHKIND_00614 5.6e-62 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KOEHKIND_00615 3.3e-129 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
KOEHKIND_00616 3.1e-172 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
KOEHKIND_00617 8e-293 2.7.1.53 G FGGY family of carbohydrate kinases, C-terminal domain
KOEHKIND_00618 8.8e-213 gatC G PTS system sugar-specific permease component
KOEHKIND_00619 1.4e-173 K Putative sugar-binding domain
KOEHKIND_00620 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
KOEHKIND_00621 2.7e-261 abcT3 P ATPases associated with a variety of cellular activities
KOEHKIND_00622 2.4e-24 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
KOEHKIND_00623 0.0 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
KOEHKIND_00624 5.5e-122 mgtC S MgtC family
KOEHKIND_00626 6.9e-201
KOEHKIND_00628 5.6e-190
KOEHKIND_00629 0.0 pgi 5.3.1.9 G Belongs to the GPI family
KOEHKIND_00633 2.4e-176 S Auxin Efflux Carrier
KOEHKIND_00634 1.7e-117 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KOEHKIND_00635 2.1e-134 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KOEHKIND_00636 7.5e-247 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KOEHKIND_00638 2.9e-91 ilvN 2.2.1.6 E ACT domain
KOEHKIND_00639 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
KOEHKIND_00640 6.1e-140 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KOEHKIND_00641 2.3e-19 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KOEHKIND_00642 2.3e-113 yceD S Uncharacterized ACR, COG1399
KOEHKIND_00643 3.6e-107
KOEHKIND_00644 1e-81 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KOEHKIND_00645 2e-58 S Protein of unknown function (DUF3039)
KOEHKIND_00646 0.0 yjjK S ABC transporter
KOEHKIND_00647 2.3e-136 guaA1 6.3.5.2 F Peptidase C26
KOEHKIND_00648 0.0 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
KOEHKIND_00649 1.4e-164 P Cation efflux family
KOEHKIND_00650 8.4e-272 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KOEHKIND_00651 1.9e-222 S Endonuclease/Exonuclease/phosphatase family
KOEHKIND_00652 1.3e-93 argO S LysE type translocator
KOEHKIND_00653 1.5e-294 ydfD EK Alanine-glyoxylate amino-transferase
KOEHKIND_00654 1e-54 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KOEHKIND_00655 1.8e-34 CP_0960 S Belongs to the UPF0109 family
KOEHKIND_00656 1.3e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KOEHKIND_00657 9.2e-165 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KOEHKIND_00658 3.4e-82 hsp20 O Hsp20/alpha crystallin family
KOEHKIND_00659 2.6e-106 XK27_02070 S Nitroreductase family
KOEHKIND_00660 1.1e-119 rsmD 2.1.1.171 L Conserved hypothetical protein 95
KOEHKIND_00661 8.6e-245 U Sodium:dicarboxylate symporter family
KOEHKIND_00662 0.0
KOEHKIND_00665 3.8e-219 steT E amino acid
KOEHKIND_00666 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
KOEHKIND_00667 1.4e-29 rpmB J Ribosomal L28 family
KOEHKIND_00668 6.5e-201 yegV G pfkB family carbohydrate kinase
KOEHKIND_00670 1e-243 yxiO S Vacuole effluxer Atg22 like
KOEHKIND_00671 2e-132 K helix_turn_helix, mercury resistance
KOEHKIND_00672 1.3e-08 T Toxic component of a toxin-antitoxin (TA) module
KOEHKIND_00673 3.7e-54 relB L RelB antitoxin
KOEHKIND_00674 1.6e-235 K Helix-turn-helix XRE-family like proteins
KOEHKIND_00675 1e-98 tam 2.1.1.144, 2.1.1.197 S Methyltransferase domain
KOEHKIND_00676 4e-22 tam 2.1.1.144, 2.1.1.197 S Methyltransferase domain
KOEHKIND_00677 8.6e-163 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
KOEHKIND_00678 3.4e-52 S Eco47II restriction endonuclease
KOEHKIND_00680 6.7e-35 D FtsK/SpoIIIE family
KOEHKIND_00682 1.6e-37 L Phage integrase family
KOEHKIND_00683 1.6e-07 L DNA integration
KOEHKIND_00688 1.6e-32
KOEHKIND_00690 0.0 fadD 6.2.1.3 I AMP-binding enzyme
KOEHKIND_00691 3e-41 K Transcriptional regulator
KOEHKIND_00693 5.6e-65
KOEHKIND_00694 1.2e-232 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
KOEHKIND_00695 4.2e-239 MA20_36090 S Psort location Cytoplasmic, score 8.87
KOEHKIND_00696 1.7e-119 K Bacterial regulatory proteins, tetR family
KOEHKIND_00697 2.7e-132 M Mechanosensitive ion channel
KOEHKIND_00698 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KOEHKIND_00699 9.6e-30 2.1.1.72 S Protein conserved in bacteria
KOEHKIND_00700 4.2e-155 fahA Q Fumarylacetoacetate (FAA) hydrolase family
KOEHKIND_00701 2.4e-66 S Domain of unknown function (DUF4854)
KOEHKIND_00702 9.7e-214 3.4.22.70 M Sortase family
KOEHKIND_00703 1.9e-276 M LPXTG cell wall anchor motif
KOEHKIND_00704 0.0 inlJ M domain protein
KOEHKIND_00705 3.6e-53 acyP 3.6.1.7 C Acylphosphatase
KOEHKIND_00706 1.2e-146 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KOEHKIND_00707 5.4e-186 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
KOEHKIND_00708 3.9e-129 M Protein of unknown function (DUF3152)
KOEHKIND_00709 3.7e-131 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
KOEHKIND_00711 1.2e-65 E Domain of unknown function (DUF5011)
KOEHKIND_00712 2e-35 S Parallel beta-helix repeats
KOEHKIND_00713 6.6e-70 rplI J Binds to the 23S rRNA
KOEHKIND_00714 2e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KOEHKIND_00715 1.9e-78 ssb1 L Single-stranded DNA-binding protein
KOEHKIND_00716 6.1e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
KOEHKIND_00717 6.7e-176 T Pfam Adenylate and Guanylate cyclase catalytic domain
KOEHKIND_00718 1.6e-118
KOEHKIND_00719 0.0 ftsK 2.7.11.1, 2.7.7.7, 3.4.21.110, 4.2.1.2 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KOEHKIND_00720 6.9e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KOEHKIND_00721 0.0 3.2.1.97 GH101 G Glycosyl hydrolase 101 beta sandwich domain
KOEHKIND_00722 3.7e-201 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
KOEHKIND_00723 2.2e-218 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KOEHKIND_00724 2.5e-178 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
KOEHKIND_00725 8.2e-173 plsC2 2.3.1.51 I Phosphate acyltransferases
KOEHKIND_00726 1.2e-128 nusG K Participates in transcription elongation, termination and antitermination
KOEHKIND_00727 1.1e-31 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KOEHKIND_00729 4e-231 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
KOEHKIND_00730 4.1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KOEHKIND_00731 3.7e-299 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KOEHKIND_00732 7.5e-216 K Psort location Cytoplasmic, score
KOEHKIND_00733 3.1e-40 rpmA J Ribosomal L27 protein
KOEHKIND_00734 3.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
KOEHKIND_00735 0.0 rne 3.1.26.12 J Ribonuclease E/G family
KOEHKIND_00736 1.3e-237 dapE 3.5.1.18 E Peptidase dimerisation domain
KOEHKIND_00737 1.9e-167 mdcF S Transporter, auxin efflux carrier (AEC) family protein
KOEHKIND_00738 3.3e-256 V Efflux ABC transporter, permease protein
KOEHKIND_00739 1.6e-163 V ATPases associated with a variety of cellular activities
KOEHKIND_00740 2.1e-58
KOEHKIND_00741 4.9e-66
KOEHKIND_00742 8.1e-279 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
KOEHKIND_00743 3.5e-188 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KOEHKIND_00744 5.2e-240 hom 1.1.1.3 E Homoserine dehydrogenase
KOEHKIND_00745 2.9e-290 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
KOEHKIND_00746 1.9e-81 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KOEHKIND_00747 1e-306 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KOEHKIND_00748 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
KOEHKIND_00749 6.8e-181 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
KOEHKIND_00750 5.2e-63 psp1 3.5.99.10 J Endoribonuclease L-PSP
KOEHKIND_00751 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
KOEHKIND_00753 6.2e-151 IQ KR domain
KOEHKIND_00754 1e-63 4.2.1.68 M Enolase C-terminal domain-like
KOEHKIND_00755 1.6e-17 4.2.1.68 M carboxylic acid catabolic process
KOEHKIND_00756 1.4e-184 K Bacterial regulatory proteins, lacI family
KOEHKIND_00758 2.8e-119 cyaA 4.6.1.1 S CYTH
KOEHKIND_00759 1.1e-162 trxA2 O Tetratricopeptide repeat
KOEHKIND_00760 7.9e-180
KOEHKIND_00761 5.4e-187
KOEHKIND_00762 1.4e-165 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
KOEHKIND_00763 6.1e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KOEHKIND_00764 2.3e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KOEHKIND_00765 4.7e-126
KOEHKIND_00766 7.3e-132 K Bacterial regulatory proteins, tetR family
KOEHKIND_00767 4.8e-225 G Transmembrane secretion effector
KOEHKIND_00768 9.8e-255 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KOEHKIND_00769 3.6e-221 pyrD 1.3.1.14 F Dihydroorotate dehydrogenase
KOEHKIND_00770 9.2e-182 S CAAX protease self-immunity
KOEHKIND_00772 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
KOEHKIND_00773 3.8e-133 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KOEHKIND_00774 2.2e-273 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KOEHKIND_00775 2.8e-138 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
KOEHKIND_00776 4.4e-252 S Calcineurin-like phosphoesterase
KOEHKIND_00779 5.7e-43 S Domain of unknown function (DUF4143)
KOEHKIND_00780 3.1e-95 S Domain of unknown function (DUF4143)
KOEHKIND_00781 1.1e-275 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KOEHKIND_00783 3.1e-124 S HAD hydrolase, family IA, variant 3
KOEHKIND_00784 1.7e-201 P NMT1/THI5 like
KOEHKIND_00785 1.7e-137 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
KOEHKIND_00786 3.7e-144
KOEHKIND_00787 1.1e-126 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
KOEHKIND_00788 4e-262 EGP Major facilitator Superfamily
KOEHKIND_00789 6.8e-98 S GtrA-like protein
KOEHKIND_00790 1.3e-62 S Macrophage migration inhibitory factor (MIF)
KOEHKIND_00791 1.3e-287 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
KOEHKIND_00792 0.0 pepD E Peptidase family C69
KOEHKIND_00793 3.7e-107 S Phosphatidylethanolamine-binding protein
KOEHKIND_00794 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
KOEHKIND_00795 0.0 lmrA2 V ABC transporter transmembrane region
KOEHKIND_00796 0.0 lmrA1 V ABC transporter, ATP-binding protein
KOEHKIND_00797 5.9e-94 ydgJ K helix_turn_helix multiple antibiotic resistance protein
KOEHKIND_00798 3.3e-191 1.1.1.65 C Aldo/keto reductase family
KOEHKIND_00800 1.8e-53 M Belongs to the glycosyl hydrolase 30 family
KOEHKIND_00801 4.8e-108 I alpha/beta hydrolase fold
KOEHKIND_00802 3.5e-205 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KOEHKIND_00803 1.3e-99 sixA T Phosphoglycerate mutase family
KOEHKIND_00804 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KOEHKIND_00805 1.4e-161 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
KOEHKIND_00806 4.5e-07
KOEHKIND_00807 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
KOEHKIND_00808 1.4e-181 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KOEHKIND_00809 2e-73 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
KOEHKIND_00810 1.5e-280 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KOEHKIND_00811 8.9e-181 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
KOEHKIND_00812 1.7e-156 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
KOEHKIND_00813 2.8e-179 pyrD 1.3.1.14 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KOEHKIND_00814 6.5e-125 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KOEHKIND_00815 3e-24 K MerR family regulatory protein
KOEHKIND_00816 8.4e-193 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
KOEHKIND_00817 1e-127
KOEHKIND_00818 1.2e-21 KLT Protein tyrosine kinase
KOEHKIND_00819 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KOEHKIND_00820 3.3e-242 vbsD V MatE
KOEHKIND_00821 9.6e-132 S Enoyl-(Acyl carrier protein) reductase
KOEHKIND_00822 4.3e-132 magIII L endonuclease III
KOEHKIND_00823 3.8e-93 laaE K Transcriptional regulator PadR-like family
KOEHKIND_00824 6.8e-176 S Membrane transport protein
KOEHKIND_00825 2.7e-69 4.1.1.44 S Cupin domain
KOEHKIND_00826 1.2e-224 hipA 2.7.11.1 S HipA N-terminal domain
KOEHKIND_00827 3.7e-41 K Helix-turn-helix
KOEHKIND_00828 1.7e-47 tam 2.1.1.144, 2.1.1.197 FG trans-aconitate 2-methyltransferase activity
KOEHKIND_00829 3.5e-18
KOEHKIND_00830 4.2e-101 K Bacterial regulatory proteins, tetR family
KOEHKIND_00831 4.7e-85 T Domain of unknown function (DUF4234)
KOEHKIND_00832 1.2e-171 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
KOEHKIND_00833 1.5e-123 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KOEHKIND_00834 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KOEHKIND_00835 1.1e-141 4.1.1.44 S Carboxymuconolactone decarboxylase family
KOEHKIND_00836 1.2e-88 dkgB S Oxidoreductase, aldo keto reductase family protein
KOEHKIND_00838 5.1e-289 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
KOEHKIND_00839 0.0 pafB K WYL domain
KOEHKIND_00840 1e-51
KOEHKIND_00841 0.0 helY L DEAD DEAH box helicase
KOEHKIND_00842 3e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
KOEHKIND_00843 1.6e-142 pgp 3.1.3.18 S HAD-hyrolase-like
KOEHKIND_00845 3.6e-90 K Putative zinc ribbon domain
KOEHKIND_00846 7.2e-126 S GyrI-like small molecule binding domain
KOEHKIND_00847 3.3e-24 L DNA integration
KOEHKIND_00848 5.5e-15
KOEHKIND_00849 7.3e-62
KOEHKIND_00850 2.7e-120 K helix_turn_helix, mercury resistance
KOEHKIND_00851 7.3e-74 garA T Inner membrane component of T3SS, cytoplasmic domain
KOEHKIND_00852 7.7e-141 S Bacterial protein of unknown function (DUF881)
KOEHKIND_00853 2.6e-31 sbp S Protein of unknown function (DUF1290)
KOEHKIND_00854 4e-173 S Bacterial protein of unknown function (DUF881)
KOEHKIND_00855 1.8e-116 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KOEHKIND_00856 1.8e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
KOEHKIND_00857 6.4e-41 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
KOEHKIND_00858 6.3e-101 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
KOEHKIND_00859 2.3e-192 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KOEHKIND_00860 4.4e-163 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KOEHKIND_00861 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KOEHKIND_00862 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
KOEHKIND_00863 7.5e-146 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KOEHKIND_00864 4.1e-103 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
KOEHKIND_00865 5.7e-30
KOEHKIND_00866 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KOEHKIND_00867 7.7e-247
KOEHKIND_00868 8.3e-168 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KOEHKIND_00869 1.1e-225 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
KOEHKIND_00870 5.5e-101 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KOEHKIND_00871 2.6e-44 yajC U Preprotein translocase subunit
KOEHKIND_00872 1.8e-201 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KOEHKIND_00873 2.5e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KOEHKIND_00874 1.8e-99 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KOEHKIND_00875 1e-131 yebC K transcriptional regulatory protein
KOEHKIND_00876 0.0 3.2.1.52 GH20 M Glycosyl hydrolase family 20, catalytic domain
KOEHKIND_00877 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KOEHKIND_00878 2.2e-250 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KOEHKIND_00881 1.5e-257
KOEHKIND_00885 2.8e-156 S PAC2 family
KOEHKIND_00886 3.2e-167 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KOEHKIND_00887 2.1e-159 G Fructosamine kinase
KOEHKIND_00888 3.4e-211 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KOEHKIND_00889 2.5e-207 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KOEHKIND_00890 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
KOEHKIND_00891 1e-201 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KOEHKIND_00892 3.1e-142 yoaK S Protein of unknown function (DUF1275)
KOEHKIND_00893 3.7e-252 brnQ U Component of the transport system for branched-chain amino acids
KOEHKIND_00894 1.2e-239 mepA_6 V MatE
KOEHKIND_00895 6.1e-162 S Sucrose-6F-phosphate phosphohydrolase
KOEHKIND_00896 3.1e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KOEHKIND_00897 8e-33 secG U Preprotein translocase SecG subunit
KOEHKIND_00898 5.3e-147 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KOEHKIND_00899 2.4e-220 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
KOEHKIND_00900 2.2e-171 whiA K May be required for sporulation
KOEHKIND_00901 2.6e-177 rapZ S Displays ATPase and GTPase activities
KOEHKIND_00902 4.3e-183 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
KOEHKIND_00903 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KOEHKIND_00904 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KOEHKIND_00905 1.4e-76
KOEHKIND_00906 5.6e-60 V MacB-like periplasmic core domain
KOEHKIND_00907 2.1e-117 K Transcriptional regulatory protein, C terminal
KOEHKIND_00908 2.2e-239 qseC 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
KOEHKIND_00909 2.2e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
KOEHKIND_00910 2.6e-302 ybiT S ABC transporter
KOEHKIND_00911 8.5e-198 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KOEHKIND_00912 1.1e-307 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KOEHKIND_00913 2.8e-207 mdsC 2.7.1.162, 2.7.1.39 S Phosphotransferase enzyme family
KOEHKIND_00914 6.4e-218 GK ROK family
KOEHKIND_00915 6.9e-178 2.7.1.2 GK ROK family
KOEHKIND_00916 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
KOEHKIND_00917 1.1e-167 G ABC transporter permease
KOEHKIND_00918 1.1e-173 G Binding-protein-dependent transport system inner membrane component
KOEHKIND_00919 4.3e-247 G Bacterial extracellular solute-binding protein
KOEHKIND_00920 5.1e-306 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KOEHKIND_00921 5.3e-74 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KOEHKIND_00922 1.4e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KOEHKIND_00923 1e-226 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KOEHKIND_00924 1.8e-176 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
KOEHKIND_00925 8.9e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KOEHKIND_00926 2.4e-133 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KOEHKIND_00927 1e-127 3.2.1.8 S alpha beta
KOEHKIND_00928 4.8e-146 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KOEHKIND_00929 3.9e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
KOEHKIND_00930 1.7e-87 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KOEHKIND_00931 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
KOEHKIND_00932 3.4e-91
KOEHKIND_00933 2.5e-200 guaB 1.1.1.205 F IMP dehydrogenase family protein
KOEHKIND_00934 3.3e-241 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
KOEHKIND_00935 4.6e-275 G ABC transporter substrate-binding protein
KOEHKIND_00936 0.0 fadD1 6.2.1.3 I AMP-binding enzyme
KOEHKIND_00937 3.3e-129 M Peptidase family M23
KOEHKIND_00939 6.2e-196 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KOEHKIND_00940 3.2e-101 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
KOEHKIND_00941 1e-159 yeaZ 2.3.1.234 O Glycoprotease family
KOEHKIND_00942 3.8e-119 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
KOEHKIND_00943 4.8e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
KOEHKIND_00944 0.0 comE S Competence protein
KOEHKIND_00945 3.8e-92 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
KOEHKIND_00946 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KOEHKIND_00947 2.6e-169 ET Bacterial periplasmic substrate-binding proteins
KOEHKIND_00948 3.7e-171 corA P CorA-like Mg2+ transporter protein
KOEHKIND_00949 3.6e-162 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
KOEHKIND_00950 4.5e-299 E Serine carboxypeptidase
KOEHKIND_00951 0.0 S Psort location Cytoplasmic, score 8.87
KOEHKIND_00952 1e-108 S Domain of unknown function (DUF4194)
KOEHKIND_00953 8.8e-284 S Psort location Cytoplasmic, score 8.87
KOEHKIND_00954 1.3e-162 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KOEHKIND_00955 2.4e-62 yeaO K Protein of unknown function, DUF488
KOEHKIND_00956 1.5e-120 ydaF_1 J Acetyltransferase (GNAT) domain
KOEHKIND_00957 1.2e-97 MA20_25245 K FR47-like protein
KOEHKIND_00958 4.3e-56 K Transcriptional regulator
KOEHKIND_00959 1.3e-100 XK27_07525 3.6.1.55 F Hydrolase of X-linked nucleoside diphosphate N terminal
KOEHKIND_00961 2.3e-184 S Acetyltransferase (GNAT) domain
KOEHKIND_00962 5.1e-23 qseC 2.7.13.3 T Histidine kinase
KOEHKIND_00963 7.9e-131 S SOS response associated peptidase (SRAP)
KOEHKIND_00964 3.2e-43
KOEHKIND_00965 5.6e-29
KOEHKIND_00966 7.3e-80 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KOEHKIND_00967 9.8e-164 rpoC M heme binding
KOEHKIND_00968 3e-28 EGP Major facilitator Superfamily
KOEHKIND_00969 2.9e-99 EGP Major facilitator Superfamily
KOEHKIND_00971 9.8e-158
KOEHKIND_00972 8.6e-96 ypjC S Putative ABC-transporter type IV
KOEHKIND_00973 2.5e-109 ycaK 1.6.5.2 S NADPH-dependent FMN reductase
KOEHKIND_00974 8.2e-193 V VanZ like family
KOEHKIND_00975 1.4e-139 KT RESPONSE REGULATOR receiver
KOEHKIND_00976 4.6e-70 pdxH S Pfam:Pyridox_oxidase
KOEHKIND_00977 2.2e-141 yijF S Domain of unknown function (DUF1287)
KOEHKIND_00978 5e-133 C Putative TM nitroreductase
KOEHKIND_00979 1.2e-108
KOEHKIND_00981 1.6e-251 nplT 3.2.1.1 GH13 G Alpha amylase, catalytic domain
KOEHKIND_00982 1.1e-77 S Bacterial PH domain
KOEHKIND_00983 1.9e-138 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
KOEHKIND_00984 1.2e-68 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KOEHKIND_00985 2.1e-263 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KOEHKIND_00987 9.1e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KOEHKIND_00988 1.6e-145 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KOEHKIND_00989 5.2e-93
KOEHKIND_00990 5.3e-237 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KOEHKIND_00991 4.6e-285 thrC 4.2.3.1 E Threonine synthase N terminus
KOEHKIND_00992 9.6e-124 S ABC-2 family transporter protein
KOEHKIND_00993 2.4e-125 S ABC-2 family transporter protein
KOEHKIND_00994 2e-177 V ATPases associated with a variety of cellular activities
KOEHKIND_00995 3.7e-58 K helix_turn_helix gluconate operon transcriptional repressor
KOEHKIND_00996 5.8e-123 S Haloacid dehalogenase-like hydrolase
KOEHKIND_00997 2.9e-294 recN L May be involved in recombinational repair of damaged DNA
KOEHKIND_00998 7.3e-183 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KOEHKIND_00999 3.9e-236 trkB P Cation transport protein
KOEHKIND_01000 6.8e-116 trkA P TrkA-N domain
KOEHKIND_01001 3.6e-104
KOEHKIND_01002 3.6e-137 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
KOEHKIND_01004 3.7e-193 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
KOEHKIND_01005 3.6e-159 L Tetratricopeptide repeat
KOEHKIND_01006 2.4e-253 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KOEHKIND_01007 4.6e-143 S Putative ABC-transporter type IV
KOEHKIND_01008 7.2e-109 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
KOEHKIND_01009 1.4e-281 argH 4.3.2.1 E argininosuccinate lyase
KOEHKIND_01010 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
KOEHKIND_01011 1.9e-16 K Putative DNA-binding domain
KOEHKIND_01012 1.1e-45
KOEHKIND_01013 2.3e-142 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
KOEHKIND_01014 1.6e-69 S Protein of unknown function (DUF4235)
KOEHKIND_01015 7.9e-131 G Phosphoglycerate mutase family
KOEHKIND_01017 2.9e-190 K Psort location Cytoplasmic, score
KOEHKIND_01018 0.0 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
KOEHKIND_01019 0.0 dnaK O Heat shock 70 kDa protein
KOEHKIND_01020 2.8e-59 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KOEHKIND_01021 2.4e-173 dnaJ1 O DnaJ molecular chaperone homology domain
KOEHKIND_01022 6.8e-87 hspR K transcriptional regulator, MerR family
KOEHKIND_01023 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR repeat-like domain
KOEHKIND_01024 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR Asp-box repeat
KOEHKIND_01025 4.7e-140 S HAD hydrolase, family IA, variant 3
KOEHKIND_01027 7.7e-126 dedA S SNARE associated Golgi protein
KOEHKIND_01028 2.6e-167 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KOEHKIND_01029 8.6e-59
KOEHKIND_01030 3.6e-130
KOEHKIND_01031 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KOEHKIND_01032 4.8e-85 K Transcriptional regulator
KOEHKIND_01034 4e-38 xylR 5.3.1.12 G MFS/sugar transport protein
KOEHKIND_01035 1.6e-213 xylR 5.3.1.12 G MFS/sugar transport protein
KOEHKIND_01036 5.9e-185 tatD L TatD related DNase
KOEHKIND_01037 0.0 kup P Transport of potassium into the cell
KOEHKIND_01038 3.3e-166 S Glutamine amidotransferase domain
KOEHKIND_01039 2.1e-137 T HD domain
KOEHKIND_01040 5.5e-181 V ABC transporter
KOEHKIND_01041 1.1e-246 V ABC transporter permease
KOEHKIND_01042 0.0 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
KOEHKIND_01043 0.0 S Psort location Cytoplasmic, score 8.87
KOEHKIND_01044 1.9e-164 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
KOEHKIND_01045 8.7e-27 thiS 2.8.1.10 H ThiS family
KOEHKIND_01047 5.2e-262
KOEHKIND_01048 2.7e-207 S Glycosyltransferase, group 2 family protein
KOEHKIND_01049 2.2e-57 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KOEHKIND_01050 2.1e-42 cbiM P PDGLE domain
KOEHKIND_01051 5e-91
KOEHKIND_01052 7.4e-216 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
KOEHKIND_01053 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KOEHKIND_01054 5.8e-152 cpaE D bacterial-type flagellum organization
KOEHKIND_01055 3.4e-191 cpaF U Type II IV secretion system protein
KOEHKIND_01056 5.7e-121 U Type ii secretion system
KOEHKIND_01057 9.5e-79 gspF NU Type II secretion system (T2SS), protein F
KOEHKIND_01058 3.2e-41 S Protein of unknown function (DUF4244)
KOEHKIND_01059 4.8e-55 U TadE-like protein
KOEHKIND_01060 3.1e-57 S TIGRFAM helicase secretion neighborhood TadE-like protein
KOEHKIND_01061 3.7e-215 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
KOEHKIND_01062 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
KOEHKIND_01063 6.7e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KOEHKIND_01064 5.3e-136 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
KOEHKIND_01065 1.8e-96 askB 1.1.1.3, 2.7.2.4 E ACT domain
KOEHKIND_01066 1.4e-211 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KOEHKIND_01067 1.7e-116
KOEHKIND_01068 4e-273 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
KOEHKIND_01069 8.7e-15 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
KOEHKIND_01070 7.9e-279 S Calcineurin-like phosphoesterase
KOEHKIND_01071 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KOEHKIND_01072 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
KOEHKIND_01073 5.4e-233 glf 5.4.99.9 M UDP-galactopyranose mutase
KOEHKIND_01074 6.1e-123 yplQ S Haemolysin-III related
KOEHKIND_01075 0.0 vpr M PA domain
KOEHKIND_01076 1.5e-187 3.6.1.27 I PAP2 superfamily
KOEHKIND_01077 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KOEHKIND_01078 1.3e-118 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KOEHKIND_01079 7.7e-211 holB 2.7.7.7 L DNA polymerase III
KOEHKIND_01080 4.4e-200 K helix_turn _helix lactose operon repressor
KOEHKIND_01081 5e-38 ptsH G PTS HPr component phosphorylation site
KOEHKIND_01082 3.6e-291 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KOEHKIND_01083 9.9e-93 S Fic/DOC family
KOEHKIND_01084 7.6e-202 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KOEHKIND_01085 5.9e-22 G MFS/sugar transport protein
KOEHKIND_01086 4.6e-308 efeU_1 P Iron permease FTR1 family
KOEHKIND_01087 6.4e-109 tpd P Fe2+ transport protein
KOEHKIND_01088 3.2e-234 S Predicted membrane protein (DUF2318)
KOEHKIND_01089 9.7e-223 macB_2 V ABC transporter permease
KOEHKIND_01090 2.4e-205 Z012_06715 V FtsX-like permease family
KOEHKIND_01091 5.7e-149 macB V ABC transporter, ATP-binding protein
KOEHKIND_01092 2.9e-70 S FMN_bind
KOEHKIND_01093 3.6e-131 yydK K UTRA
KOEHKIND_01094 3.6e-67 S haloacid dehalogenase-like hydrolase
KOEHKIND_01095 7.3e-250 gmuC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KOEHKIND_01096 4.3e-49 celA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
KOEHKIND_01097 7.5e-39 celC 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
KOEHKIND_01098 4e-294 bglA 3.2.1.86 GT1 G Glycosyl hydrolase family 1
KOEHKIND_01099 3.3e-31 Q phosphatase activity
KOEHKIND_01100 7e-81
KOEHKIND_01101 3.5e-241 S Putative ABC-transporter type IV
KOEHKIND_01102 1.1e-161 S Sucrose-6F-phosphate phosphohydrolase
KOEHKIND_01104 3e-73 E IrrE N-terminal-like domain
KOEHKIND_01105 6.5e-81 K Winged helix DNA-binding domain
KOEHKIND_01106 7e-301 V ABC transporter, ATP-binding protein
KOEHKIND_01107 0.0 V ABC transporter transmembrane region
KOEHKIND_01108 1.6e-84
KOEHKIND_01109 1.9e-52 XK26_04485 P Cobalt transport protein
KOEHKIND_01111 9.2e-305 pepD E Peptidase family C69
KOEHKIND_01112 0.0 S Glycosyl hydrolases related to GH101 family, GH129
KOEHKIND_01113 1.5e-197 XK27_01805 M Glycosyltransferase like family 2
KOEHKIND_01114 1.2e-116 icaR K Bacterial regulatory proteins, tetR family
KOEHKIND_01116 2.4e-194 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KOEHKIND_01117 1.3e-219 amt U Ammonium Transporter Family
KOEHKIND_01118 1e-54 glnB K Nitrogen regulatory protein P-II
KOEHKIND_01119 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
KOEHKIND_01120 1.1e-18 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
KOEHKIND_01121 7e-251 dinF V MatE
KOEHKIND_01122 7.5e-258 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KOEHKIND_01123 1.7e-282 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
KOEHKIND_01124 7.5e-143 cobQ S CobB/CobQ-like glutamine amidotransferase domain
KOEHKIND_01125 3.5e-19 S granule-associated protein
KOEHKIND_01126 0.0 ubiB S ABC1 family
KOEHKIND_01127 0.0 pacS 3.6.3.54 P E1-E2 ATPase
KOEHKIND_01128 9.6e-43 csoR S Metal-sensitive transcriptional repressor
KOEHKIND_01129 1.3e-214 rmuC S RmuC family
KOEHKIND_01130 5.9e-129 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KOEHKIND_01131 6.9e-156 spoU 2.1.1.185 J RNA methyltransferase TrmH family
KOEHKIND_01132 9.6e-59 V ABC transporter
KOEHKIND_01133 1e-60 V ABC transporter
KOEHKIND_01134 6.2e-48 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KOEHKIND_01135 6.4e-290 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KOEHKIND_01136 1.4e-286 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KOEHKIND_01137 1.7e-198 2.3.1.57 J Acetyltransferase (GNAT) domain
KOEHKIND_01138 3.3e-52 S Protein of unknown function (DUF2469)
KOEHKIND_01139 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
KOEHKIND_01140 3.6e-304 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KOEHKIND_01141 7.2e-236 E Aminotransferase class I and II
KOEHKIND_01142 3.1e-90 lrp_3 K helix_turn_helix ASNC type
KOEHKIND_01143 4.7e-73 tyrA 5.4.99.5 E Chorismate mutase type II
KOEHKIND_01144 0.0 S domain protein
KOEHKIND_01145 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KOEHKIND_01146 4.3e-294 E Bacterial extracellular solute-binding proteins, family 5 Middle
KOEHKIND_01147 1.5e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KOEHKIND_01148 4.8e-134 KT Transcriptional regulatory protein, C terminal
KOEHKIND_01149 1.4e-125
KOEHKIND_01151 2.7e-100 mntP P Probably functions as a manganese efflux pump
KOEHKIND_01154 5.2e-92 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KOEHKIND_01155 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
KOEHKIND_01156 0.0 K RNA polymerase II activating transcription factor binding
KOEHKIND_01157 4.6e-35
KOEHKIND_01159 2e-207 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KOEHKIND_01160 6e-146 atpB C it plays a direct role in the translocation of protons across the membrane
KOEHKIND_01162 1.2e-30 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KOEHKIND_01163 4.6e-62 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KOEHKIND_01164 7e-150 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KOEHKIND_01165 0.0 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KOEHKIND_01166 2.7e-166 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KOEHKIND_01167 1.5e-283 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KOEHKIND_01168 8.7e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KOEHKIND_01169 2.3e-130 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
KOEHKIND_01170 3.9e-145 QT PucR C-terminal helix-turn-helix domain
KOEHKIND_01171 0.0
KOEHKIND_01172 9.9e-152 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
KOEHKIND_01173 4.2e-93 bioY S BioY family
KOEHKIND_01174 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
KOEHKIND_01175 8e-307 pccB I Carboxyl transferase domain
KOEHKIND_01176 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
KOEHKIND_01177 5.9e-100 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KOEHKIND_01178 1.3e-162 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
KOEHKIND_01180 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
KOEHKIND_01181 4e-119
KOEHKIND_01182 3e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KOEHKIND_01183 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KOEHKIND_01184 9.5e-116 xylR K purine nucleotide biosynthetic process
KOEHKIND_01185 1.2e-92 lemA S LemA family
KOEHKIND_01186 0.0 S Predicted membrane protein (DUF2207)
KOEHKIND_01187 1.9e-75 megL 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
KOEHKIND_01188 1.6e-189 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KOEHKIND_01189 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KOEHKIND_01190 1.5e-98 nrdI F Probably involved in ribonucleotide reductase function
KOEHKIND_01191 2.2e-41 nrdH O Glutaredoxin
KOEHKIND_01192 4.6e-168 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
KOEHKIND_01193 7.5e-100 L Transposase and inactivated derivatives IS30 family
KOEHKIND_01194 0.0 yegQ O Peptidase family U32 C-terminal domain
KOEHKIND_01195 1e-187 yfiH Q Multi-copper polyphenol oxidoreductase laccase
KOEHKIND_01196 1.1e-144 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KOEHKIND_01197 8e-128 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KOEHKIND_01198 4e-47 D nuclear chromosome segregation
KOEHKIND_01199 3.2e-269 pepC 3.4.22.40 E Peptidase C1-like family
KOEHKIND_01200 3.4e-170 L Excalibur calcium-binding domain
KOEHKIND_01201 1.1e-219 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KOEHKIND_01202 2e-242 EGP Major facilitator Superfamily
KOEHKIND_01203 8.2e-108 K helix_turn_helix, Arsenical Resistance Operon Repressor
KOEHKIND_01204 1.7e-240 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KOEHKIND_01205 8.7e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KOEHKIND_01206 4.2e-245 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
KOEHKIND_01207 3.7e-128 KT Transcriptional regulatory protein, C terminal
KOEHKIND_01208 1.4e-169 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
KOEHKIND_01209 3.8e-171 pstC P probably responsible for the translocation of the substrate across the membrane
KOEHKIND_01210 6.2e-180 pstA P Phosphate transport system permease
KOEHKIND_01211 3.6e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KOEHKIND_01212 3e-170 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
KOEHKIND_01213 1.4e-12 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
KOEHKIND_01214 1.2e-210 pbuO S Permease family
KOEHKIND_01216 0.0 guxA1 3.2.1.18, 3.2.1.91 GH33,GH6 G BNR repeat-like domain
KOEHKIND_01217 3.8e-174 xynB2 1.1.1.169 E lipolytic protein G-D-S-L family
KOEHKIND_01218 2.1e-88 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KOEHKIND_01219 1.3e-37 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KOEHKIND_01221 5.7e-244 T Forkhead associated domain
KOEHKIND_01222 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
KOEHKIND_01223 9.6e-42
KOEHKIND_01224 6.2e-109 flgA NO SAF
KOEHKIND_01225 3.2e-38 fmdB S Putative regulatory protein
KOEHKIND_01226 1.8e-121 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
KOEHKIND_01227 5.8e-148 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
KOEHKIND_01228 1.4e-147
KOEHKIND_01229 1.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KOEHKIND_01230 1.1e-128 bla1 3.5.2.6 V Beta-lactamase enzyme family
KOEHKIND_01231 9.2e-52 moxR S ATPase family associated with various cellular activities (AAA)
KOEHKIND_01235 1.9e-25 rpmG J Ribosomal protein L33
KOEHKIND_01236 1.5e-214 murB 1.3.1.98 M Cell wall formation
KOEHKIND_01237 9e-61 fdxA C 4Fe-4S binding domain
KOEHKIND_01238 3.6e-224 dapC E Aminotransferase class I and II
KOEHKIND_01239 3.3e-239 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KOEHKIND_01241 1.1e-256 M Bacterial capsule synthesis protein PGA_cap
KOEHKIND_01242 2e-112 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
KOEHKIND_01243 3.3e-119
KOEHKIND_01244 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
KOEHKIND_01245 3.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KOEHKIND_01246 8.8e-68 rpsI J Belongs to the universal ribosomal protein uS9 family
KOEHKIND_01247 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
KOEHKIND_01248 8.2e-232 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
KOEHKIND_01249 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KOEHKIND_01250 1.9e-166 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
KOEHKIND_01251 2.4e-27 ywiC S YwiC-like protein
KOEHKIND_01252 2.6e-105 ywiC S YwiC-like protein
KOEHKIND_01253 5.2e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
KOEHKIND_01254 4.2e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KOEHKIND_01255 3.9e-119 rplD J Forms part of the polypeptide exit tunnel
KOEHKIND_01256 2.6e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KOEHKIND_01257 4.2e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KOEHKIND_01258 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KOEHKIND_01259 4.3e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KOEHKIND_01260 7.5e-96 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KOEHKIND_01261 5.8e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KOEHKIND_01262 5e-38 rpmC J Belongs to the universal ribosomal protein uL29 family
KOEHKIND_01263 3.5e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KOEHKIND_01264 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KOEHKIND_01265 3.5e-52 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KOEHKIND_01266 2.2e-102 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KOEHKIND_01267 9.2e-18 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KOEHKIND_01268 4.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KOEHKIND_01269 2.1e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KOEHKIND_01270 1.1e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KOEHKIND_01271 1.5e-100 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KOEHKIND_01272 1e-24 rpmD J Ribosomal protein L30p/L7e
KOEHKIND_01273 2.7e-63 rplO J binds to the 23S rRNA
KOEHKIND_01274 4.7e-249 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KOEHKIND_01275 3.8e-99 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KOEHKIND_01276 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KOEHKIND_01277 6.5e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KOEHKIND_01278 3.3e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KOEHKIND_01279 1.1e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KOEHKIND_01280 8.9e-184 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KOEHKIND_01281 2.8e-64 rplQ J Ribosomal protein L17
KOEHKIND_01282 0.0 3.2.1.52 GH20 G hydrolase family 20, catalytic
KOEHKIND_01283 6.4e-173 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KOEHKIND_01284 0.0 gcs2 S A circularly permuted ATPgrasp
KOEHKIND_01285 5e-153 E Transglutaminase/protease-like homologues
KOEHKIND_01287 8.3e-26
KOEHKIND_01288 7.9e-45 L Transposase and inactivated derivatives
KOEHKIND_01289 5.3e-157
KOEHKIND_01290 2.8e-188 nusA K Participates in both transcription termination and antitermination
KOEHKIND_01291 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KOEHKIND_01292 4.7e-84 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KOEHKIND_01293 1.6e-238 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KOEHKIND_01294 2.2e-232 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
KOEHKIND_01295 2.5e-253 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KOEHKIND_01296 1e-105
KOEHKIND_01298 5.4e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KOEHKIND_01299 7.8e-202 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KOEHKIND_01300 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
KOEHKIND_01301 5.2e-262 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KOEHKIND_01302 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
KOEHKIND_01304 1.4e-39 M Spy0128-like isopeptide containing domain
KOEHKIND_01305 2.5e-29 M Spy0128-like isopeptide containing domain
KOEHKIND_01306 0.0 crr G pts system, glucose-specific IIABC component
KOEHKIND_01307 7.6e-152 arbG K CAT RNA binding domain
KOEHKIND_01308 5.1e-212 I Diacylglycerol kinase catalytic domain
KOEHKIND_01309 0.0 nucH 3.1.3.5 F 5'-nucleotidase, C-terminal domain
KOEHKIND_01310 5.6e-229 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KOEHKIND_01312 0.0 nagLU 3.1.4.53, 3.2.1.21, 3.2.1.50 GH3 G Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
KOEHKIND_01314 1.5e-94
KOEHKIND_01315 0.0 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KOEHKIND_01316 4.2e-186 opcA G Glucose-6-phosphate dehydrogenase subunit
KOEHKIND_01317 2.3e-142 pgl 3.1.1.31 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
KOEHKIND_01319 5.3e-278 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KOEHKIND_01320 9.2e-126 degU K helix_turn_helix, Lux Regulon
KOEHKIND_01321 2e-272 tcsS3 KT PspC domain
KOEHKIND_01322 2.1e-289 pspC KT PspC domain
KOEHKIND_01323 7.3e-135
KOEHKIND_01324 1.5e-112 S Protein of unknown function (DUF4125)
KOEHKIND_01325 0.0 S Domain of unknown function (DUF4037)
KOEHKIND_01326 2.9e-218 araJ EGP Major facilitator Superfamily
KOEHKIND_01328 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KOEHKIND_01329 9.5e-175 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
KOEHKIND_01330 4.9e-139 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KOEHKIND_01331 1.8e-09 EGP Major facilitator Superfamily
KOEHKIND_01332 1.3e-117 phoU P Plays a role in the regulation of phosphate uptake
KOEHKIND_01333 2.8e-219 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
KOEHKIND_01334 2.6e-39
KOEHKIND_01335 1.8e-215 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KOEHKIND_01336 3.5e-183 usp 3.5.1.28 CBM50 S CHAP domain
KOEHKIND_01337 1.7e-108 M NlpC/P60 family
KOEHKIND_01338 1.6e-191 T Universal stress protein family
KOEHKIND_01339 1e-72 attW O OsmC-like protein
KOEHKIND_01340 1.9e-174 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KOEHKIND_01341 4.6e-128 folA 1.5.1.3 H dihydrofolate reductase
KOEHKIND_01342 4e-95 ptpA 3.1.3.48 T low molecular weight
KOEHKIND_01343 3.7e-196 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
KOEHKIND_01344 8.2e-38 azlD E Branched-chain amino acid transport protein (AzlD)
KOEHKIND_01345 9.9e-112 vex2 V ABC transporter, ATP-binding protein
KOEHKIND_01346 9.5e-212 vex1 V Efflux ABC transporter, permease protein
KOEHKIND_01347 4.7e-220 vex3 V ABC transporter permease
KOEHKIND_01348 2.3e-96 S RloB-like protein
KOEHKIND_01349 2.9e-201 S AAA domain, putative AbiEii toxin, Type IV TA system
KOEHKIND_01350 1.7e-11 S Psort location CytoplasmicMembrane, score 9.99
KOEHKIND_01351 3.7e-117 O Subtilase family
KOEHKIND_01353 7.5e-200 L Transposase, Mutator family
KOEHKIND_01355 8.3e-182 lacR K Transcriptional regulator, LacI family
KOEHKIND_01356 1.7e-90 nagA 3.5.1.25 G Amidohydrolase family
KOEHKIND_01357 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
KOEHKIND_01358 1.7e-268 lacS G Psort location CytoplasmicMembrane, score 10.00
KOEHKIND_01360 1.8e-175 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KOEHKIND_01361 6.9e-200 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KOEHKIND_01362 5.7e-68 S Domain of unknown function (DUF4190)
KOEHKIND_01365 8.1e-205 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
KOEHKIND_01366 4.3e-177 3.4.14.13 M Glycosyltransferase like family 2
KOEHKIND_01367 5.7e-273 S AI-2E family transporter
KOEHKIND_01368 1.3e-232 epsG M Glycosyl transferase family 21
KOEHKIND_01369 1.7e-168 natA V ATPases associated with a variety of cellular activities
KOEHKIND_01370 5e-309
KOEHKIND_01371 4.5e-261 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
KOEHKIND_01372 2.3e-212 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KOEHKIND_01373 9.4e-98 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KOEHKIND_01374 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KOEHKIND_01375 4.5e-100 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
KOEHKIND_01376 2.3e-164 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KOEHKIND_01377 1.4e-292 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KOEHKIND_01378 1.9e-76 S Protein of unknown function (DUF3180)
KOEHKIND_01379 2.1e-171 tesB I Thioesterase-like superfamily
KOEHKIND_01380 0.0 3.2.1.52, 3.2.1.83 GH16,GH20 G hydrolase family 20, catalytic
KOEHKIND_01381 2.4e-306 yjjK S ATP-binding cassette protein, ChvD family
KOEHKIND_01382 7.6e-153 M domain, Protein
KOEHKIND_01383 2e-126
KOEHKIND_01384 4.4e-115 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KOEHKIND_01385 5e-13 S Protein of unknown function (DUF979)
KOEHKIND_01386 6.6e-34 S DUF218 domain
KOEHKIND_01387 5.2e-61 S DUF218 domain
KOEHKIND_01389 2.3e-113 S Pyridoxamine 5'-phosphate oxidase
KOEHKIND_01390 3.7e-159 I alpha/beta hydrolase fold
KOEHKIND_01391 3.5e-299 S ATPases associated with a variety of cellular activities
KOEHKIND_01392 3.7e-179 glkA 2.7.1.2 G ROK family
KOEHKIND_01393 5.2e-10 K Winged helix DNA-binding domain
KOEHKIND_01394 9.5e-75 EGP Major facilitator superfamily
KOEHKIND_01395 9.3e-36 1.1.1.122, 1.1.1.65 C Aldo/keto reductase family
KOEHKIND_01396 3.4e-252 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
KOEHKIND_01397 1.3e-215 MA20_36090 S Psort location Cytoplasmic, score 8.87
KOEHKIND_01398 1.9e-26 L Transposase
KOEHKIND_01400 1.5e-147 S Sulfite exporter TauE/SafE
KOEHKIND_01401 8.7e-146 V FtsX-like permease family
KOEHKIND_01403 4.2e-164 EG EamA-like transporter family
KOEHKIND_01404 0.0 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
KOEHKIND_01405 1.2e-141 3.5.2.6 V Beta-lactamase enzyme family
KOEHKIND_01406 8.3e-170 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
KOEHKIND_01407 1.5e-108
KOEHKIND_01408 7.1e-258 cma 2.1.1.79 M Mycolic acid cyclopropane synthetase
KOEHKIND_01409 1.3e-177 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
KOEHKIND_01410 2.8e-163 glcU G Sugar transport protein
KOEHKIND_01411 9.5e-68 K helix_turn_helix, arabinose operon control protein
KOEHKIND_01412 3.6e-44 K helix_turn_helix, arabinose operon control protein
KOEHKIND_01413 1.8e-21 K helix_turn_helix, arabinose operon control protein
KOEHKIND_01415 3.9e-36 rpmE J Binds the 23S rRNA
KOEHKIND_01416 6.5e-188 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KOEHKIND_01417 3e-184 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KOEHKIND_01418 2.4e-55 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
KOEHKIND_01419 5.2e-116 ywlC 2.7.7.87 J Belongs to the SUA5 family
KOEHKIND_01420 6.2e-192 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
KOEHKIND_01421 4.1e-289 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KOEHKIND_01422 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
KOEHKIND_01423 1.4e-109 KT Transcriptional regulatory protein, C terminal
KOEHKIND_01424 2.8e-122 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
KOEHKIND_01425 8.4e-159 supH S Sucrose-6F-phosphate phosphohydrolase
KOEHKIND_01426 3.9e-270 recD2 3.6.4.12 L PIF1-like helicase
KOEHKIND_01427 7.4e-39 GT87 NU Tfp pilus assembly protein FimV
KOEHKIND_01428 7.9e-185 phoN I PAP2 superfamily
KOEHKIND_01429 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KOEHKIND_01430 2.4e-170
KOEHKIND_01431 4.6e-120 L Single-strand binding protein family
KOEHKIND_01432 0.0 pepO 3.4.24.71 O Peptidase family M13
KOEHKIND_01433 3.1e-127 S Short repeat of unknown function (DUF308)
KOEHKIND_01434 1.1e-149 map 3.4.11.18 E Methionine aminopeptidase
KOEHKIND_01435 1.1e-250 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
KOEHKIND_01436 5.1e-101 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
KOEHKIND_01437 8.4e-198 yghZ C Aldo/keto reductase family
KOEHKIND_01438 0.0 ctpE P E1-E2 ATPase
KOEHKIND_01439 0.0 macB_2 V ATPases associated with a variety of cellular activities
KOEHKIND_01440 1.7e-213 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KOEHKIND_01441 2.1e-260 nox 1.6.3.4 C Pyridine nucleotide-disulphide oxidoreductase
KOEHKIND_01442 4.4e-233 metC 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
KOEHKIND_01443 1.5e-244 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
KOEHKIND_01444 1.9e-124 XK27_08050 O prohibitin homologues
KOEHKIND_01445 7.9e-274 aldH 1.2.1.3, 1.2.1.5 C Aldehyde dehydrogenase family
KOEHKIND_01446 5e-55 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
KOEHKIND_01447 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KOEHKIND_01449 0.0 3.2.1.51 GH29 G Alpha-L-fucosidase
KOEHKIND_01450 7.7e-21 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
KOEHKIND_01451 1.9e-189 K Periplasmic binding protein domain
KOEHKIND_01452 5.5e-124 G ABC transporter permease
KOEHKIND_01453 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
KOEHKIND_01454 1.1e-63 G carbohydrate transport
KOEHKIND_01455 8.8e-278 G Bacterial extracellular solute-binding protein
KOEHKIND_01456 3.6e-143 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KOEHKIND_01457 1.8e-309 E ABC transporter, substrate-binding protein, family 5
KOEHKIND_01458 1.6e-169 P Binding-protein-dependent transport system inner membrane component
KOEHKIND_01459 2.9e-163 EP Binding-protein-dependent transport system inner membrane component
KOEHKIND_01460 5.2e-142 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
KOEHKIND_01461 4.4e-155 sapF E ATPases associated with a variety of cellular activities
KOEHKIND_01462 1.9e-189 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KOEHKIND_01463 3.1e-29 L Transposase
KOEHKIND_01464 4.4e-45 L Transposase DDE domain
KOEHKIND_01465 1.6e-290 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KOEHKIND_01466 0.0 3.6.4.12 K Putative DNA-binding domain
KOEHKIND_01467 2.5e-202 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KOEHKIND_01468 0.0
KOEHKIND_01469 2.4e-107 rfbJ M Glycosyl transferase family 2
KOEHKIND_01470 2.5e-206 lytC 2.1.1.197, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
KOEHKIND_01471 3e-86 lytC 2.1.1.197, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
KOEHKIND_01472 1.8e-28 I transferase activity, transferring acyl groups other than amino-acyl groups
KOEHKIND_01473 1.8e-203 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KOEHKIND_01474 1.5e-101 T protein histidine kinase activity
KOEHKIND_01475 2.3e-87 K LytTr DNA-binding domain
KOEHKIND_01476 8.7e-47 S Protein of unknown function (DUF3073)
KOEHKIND_01477 3.2e-203 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
KOEHKIND_01478 1.8e-195 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
KOEHKIND_01479 2.1e-55 S Amidohydrolase family
KOEHKIND_01480 1.9e-152 S Amidohydrolase family
KOEHKIND_01481 0.0 yjjP S Threonine/Serine exporter, ThrE
KOEHKIND_01482 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KOEHKIND_01483 8.1e-238 yhjX EGP Major facilitator Superfamily
KOEHKIND_01484 6.5e-309 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
KOEHKIND_01485 0.0 trxB1 1.8.1.9 C Thioredoxin domain
KOEHKIND_01486 2.9e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
KOEHKIND_01487 2e-118 cah 4.2.1.1 P Reversible hydration of carbon dioxide
KOEHKIND_01488 3e-75 K helix_turn _helix lactose operon repressor
KOEHKIND_01489 1.2e-241 ytfL P Transporter associated domain
KOEHKIND_01490 2e-189 yddG EG EamA-like transporter family
KOEHKIND_01491 1.9e-83 dps P Belongs to the Dps family
KOEHKIND_01492 2.3e-136 S Protein of unknown function DUF45
KOEHKIND_01493 3.4e-251 ulaA 2.7.1.194 S PTS system sugar-specific permease component
KOEHKIND_01494 3.3e-40 ulaC 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
KOEHKIND_01495 3.3e-77 ulaC 2.7.1.194, 2.7.1.197, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KOEHKIND_01496 2.8e-188 K helix_turn _helix lactose operon repressor
KOEHKIND_01497 0.0 G Glycosyl hydrolase family 20, domain 2
KOEHKIND_01500 0.0 3.2.1.55 GH51 G arabinose metabolic process
KOEHKIND_01501 2.5e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KOEHKIND_01502 2.5e-124 gntR K FCD
KOEHKIND_01503 2.3e-259 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
KOEHKIND_01504 1.9e-24 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
KOEHKIND_01507 9.4e-14 K Helix-turn-helix domain
KOEHKIND_01508 3.4e-18 S Domain of unknown function (DUF4160)
KOEHKIND_01509 9.6e-42 S Protein of unknown function (DUF2442)
KOEHKIND_01510 6.7e-09 K helix_turn _helix lactose operon repressor
KOEHKIND_01511 1.2e-227 I Serine aminopeptidase, S33
KOEHKIND_01512 1.6e-187 K Periplasmic binding protein domain
KOEHKIND_01513 7.9e-187 G Glycosyl hydrolases family 43
KOEHKIND_01514 5.7e-21 abfA1 3.2.1.55 GH51 G arabinose metabolic process
KOEHKIND_01515 6.7e-72 S Transmembrane domain of unknown function (DUF3566)
KOEHKIND_01516 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KOEHKIND_01517 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KOEHKIND_01518 1.2e-87 S Protein of unknown function (DUF721)
KOEHKIND_01519 1.2e-239 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KOEHKIND_01520 6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KOEHKIND_01521 2e-299 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KOEHKIND_01522 4.5e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
KOEHKIND_01523 1e-171 yidC U Membrane protein insertase, YidC Oxa1 family
KOEHKIND_01524 8.6e-93 jag S Putative single-stranded nucleic acids-binding domain
KOEHKIND_01525 1.3e-125 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
KOEHKIND_01526 3.8e-179 parA D CobQ CobB MinD ParA nucleotide binding domain protein
KOEHKIND_01527 4.4e-242 parB K Belongs to the ParB family
KOEHKIND_01528 1e-202 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KOEHKIND_01529 0.0 murJ KLT MviN-like protein
KOEHKIND_01530 0.0 M Conserved repeat domain
KOEHKIND_01531 5.2e-124 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
KOEHKIND_01532 2.8e-279 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
KOEHKIND_01533 6.7e-113 S LytR cell envelope-related transcriptional attenuator
KOEHKIND_01534 9.3e-168 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KOEHKIND_01535 8.2e-171 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KOEHKIND_01536 8.9e-220 S G5
KOEHKIND_01538 6.4e-151 O Thioredoxin
KOEHKIND_01539 0.0 KLT Protein tyrosine kinase
KOEHKIND_01540 1.2e-174 K Psort location Cytoplasmic, score
KOEHKIND_01541 3.3e-211 ugpC E Belongs to the ABC transporter superfamily
KOEHKIND_01542 9.8e-100 L Helix-turn-helix domain
KOEHKIND_01543 0.0 S LPXTG-motif cell wall anchor domain protein
KOEHKIND_01544 1.4e-242 M LPXTG-motif cell wall anchor domain protein
KOEHKIND_01545 4.5e-180 3.4.22.70 M Sortase family
KOEHKIND_01546 2.4e-153
KOEHKIND_01547 3e-270 KLT Domain of unknown function (DUF4032)
KOEHKIND_01548 9.9e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KOEHKIND_01550 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
KOEHKIND_01551 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
KOEHKIND_01552 5.3e-112 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
KOEHKIND_01553 0.0 yjcE P Sodium/hydrogen exchanger family
KOEHKIND_01554 1.2e-145 ypfH S Phospholipase/Carboxylesterase
KOEHKIND_01555 1.1e-83 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KOEHKIND_01556 1.3e-234 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
KOEHKIND_01557 3e-144 cobB2 K Sir2 family
KOEHKIND_01558 4.4e-109
KOEHKIND_01559 4e-192 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
KOEHKIND_01560 3.5e-219 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
KOEHKIND_01561 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
KOEHKIND_01562 2.3e-92 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KOEHKIND_01563 3.6e-31 J Acetyltransferase (GNAT) domain
KOEHKIND_01564 7.1e-94 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KOEHKIND_01565 1.5e-269 yhdG E aromatic amino acid transport protein AroP K03293
KOEHKIND_01566 9e-264 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KOEHKIND_01567 2.9e-248 dgt 3.1.5.1 F Phosphohydrolase-associated domain
KOEHKIND_01568 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KOEHKIND_01569 3.9e-159 K Helix-turn-helix domain, rpiR family
KOEHKIND_01570 2e-230 K Putative ATP-dependent DNA helicase recG C-terminal
KOEHKIND_01571 5.3e-44 S Memo-like protein
KOEHKIND_01573 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KOEHKIND_01574 4.5e-180 adh3 C Zinc-binding dehydrogenase
KOEHKIND_01575 4.7e-85 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KOEHKIND_01576 6.2e-229 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KOEHKIND_01577 4.3e-73 zur P Belongs to the Fur family
KOEHKIND_01578 2.6e-45
KOEHKIND_01579 2.6e-154 S TIGRFAM TIGR03943 family protein
KOEHKIND_01580 2e-200 ycgR S Predicted permease
KOEHKIND_01581 2.3e-23 J Ribosomal L32p protein family
KOEHKIND_01582 8.2e-15 rpmJ J Ribosomal protein L36
KOEHKIND_01583 5.7e-42 rpmE2 J Ribosomal protein L31
KOEHKIND_01584 7.5e-49 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KOEHKIND_01585 2.6e-46 rpmB J Ribosomal L28 family
KOEHKIND_01586 1.8e-139 S cobalamin synthesis protein
KOEHKIND_01587 1.3e-162 P Zinc-uptake complex component A periplasmic
KOEHKIND_01589 0.0 lysX S Uncharacterised conserved protein (DUF2156)
KOEHKIND_01590 1e-246 S Putative esterase
KOEHKIND_01591 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
KOEHKIND_01592 5e-240 purD 6.3.4.13 F Belongs to the GARS family
KOEHKIND_01593 2e-186 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KOEHKIND_01594 5.1e-292 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KOEHKIND_01595 2.8e-304 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
KOEHKIND_01596 2e-32
KOEHKIND_01597 1.8e-68 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KOEHKIND_01598 8.9e-33 K DNA-binding transcription factor activity
KOEHKIND_01599 1.4e-116 mug 3.2.2.28 L Uracil DNA glycosylase superfamily
KOEHKIND_01600 9e-97 S Protein of unknown function (DUF4230)
KOEHKIND_01601 3.7e-109
KOEHKIND_01602 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
KOEHKIND_01603 3.8e-139 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KOEHKIND_01604 1.9e-234 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KOEHKIND_01605 0.0 M Parallel beta-helix repeats
KOEHKIND_01606 1.2e-227 M Glycosyl transferase 4-like domain
KOEHKIND_01607 1.3e-198 ltaE 4.1.2.48 E Beta-eliminating lyase
KOEHKIND_01609 9.3e-62 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KOEHKIND_01610 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KOEHKIND_01611 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KOEHKIND_01612 8.1e-232 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KOEHKIND_01613 0.0 S Esterase-like activity of phytase
KOEHKIND_01614 9.5e-190 EGP Transmembrane secretion effector
KOEHKIND_01616 3.3e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KOEHKIND_01617 1.3e-93 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KOEHKIND_01618 1.1e-236 carA 6.3.5.5 F Belongs to the CarA family
KOEHKIND_01619 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
KOEHKIND_01620 4.8e-301 gmk 2.4.2.10, 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
KOEHKIND_01621 0.0 S Protein of unknown function DUF262
KOEHKIND_01622 1.1e-116 K helix_turn_helix, Lux Regulon
KOEHKIND_01623 8.4e-268 T Histidine kinase
KOEHKIND_01624 1e-97 S Domain of unknown function (DUF5067)
KOEHKIND_01625 6.6e-132 ybhL S Belongs to the BI1 family
KOEHKIND_01626 1.1e-167 ydeD EG EamA-like transporter family
KOEHKIND_01627 3.2e-121 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
KOEHKIND_01628 2.1e-279 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KOEHKIND_01629 9e-185 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KOEHKIND_01630 1.3e-136 fic D Fic/DOC family
KOEHKIND_01631 0.0 ftsK D FtsK SpoIIIE family protein
KOEHKIND_01632 9.2e-124 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KOEHKIND_01633 1.3e-96 cinA 3.5.1.42 S Belongs to the CinA family
KOEHKIND_01634 1.6e-80 K Helix-turn-helix XRE-family like proteins
KOEHKIND_01635 3.7e-40 S Protein of unknown function (DUF3046)
KOEHKIND_01636 8e-216 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KOEHKIND_01637 7.1e-74 recX S Modulates RecA activity
KOEHKIND_01638 1e-07
KOEHKIND_01640 6.7e-111 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KOEHKIND_01641 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KOEHKIND_01642 3e-190 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KOEHKIND_01643 1.5e-109
KOEHKIND_01644 1e-133 plsC2 2.3.1.51 I Phosphate acyltransferases
KOEHKIND_01645 0.0 pknL 2.7.11.1 KLT PASTA
KOEHKIND_01646 1.4e-201 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
KOEHKIND_01647 8.5e-122
KOEHKIND_01648 6.3e-181 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KOEHKIND_01649 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
KOEHKIND_01650 5.2e-278 aspA 4.3.1.1 E Fumarase C C-terminus
KOEHKIND_01651 1.2e-36 K Transcriptional regulator
KOEHKIND_01652 0.0 lhr L DEAD DEAH box helicase
KOEHKIND_01653 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
KOEHKIND_01654 9.5e-236 S Type I phosphodiesterase / nucleotide pyrophosphatase
KOEHKIND_01655 1.2e-186 S Protein of unknown function (DUF3071)
KOEHKIND_01656 1.4e-47 S Domain of unknown function (DUF4193)
KOEHKIND_01657 2.2e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
KOEHKIND_01658 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KOEHKIND_01659 9e-28
KOEHKIND_01660 1.4e-65 L Phage integrase family
KOEHKIND_01661 6.7e-43 I alpha/beta hydrolase fold
KOEHKIND_01662 3.8e-24 rarD S Rard protein
KOEHKIND_01663 4.1e-89 rarD 3.4.17.13 E Rard protein
KOEHKIND_01664 4.2e-29
KOEHKIND_01665 8.4e-222 L Uncharacterized conserved protein (DUF2075)
KOEHKIND_01666 4.2e-53 V Abi-like protein
KOEHKIND_01667 1.2e-185 L Transposase
KOEHKIND_01668 4.2e-40 L Helix-turn-helix domain
KOEHKIND_01669 6.3e-187 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KOEHKIND_01670 2.1e-111 S Sel1-like repeats.
KOEHKIND_01671 6.9e-159 ybeM S Carbon-nitrogen hydrolase
KOEHKIND_01672 3.6e-182 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
KOEHKIND_01673 5.6e-244 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
KOEHKIND_01674 3.6e-82
KOEHKIND_01675 2.7e-304 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
KOEHKIND_01676 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
KOEHKIND_01677 0.0 tetP J Elongation factor G, domain IV
KOEHKIND_01678 2.3e-287 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
KOEHKIND_01679 7.5e-107 V ATPases associated with a variety of cellular activities
KOEHKIND_01680 4.9e-186
KOEHKIND_01681 2.1e-106 K Cro/C1-type HTH DNA-binding domain
KOEHKIND_01682 4.4e-175 L Replication initiation factor
KOEHKIND_01683 1e-20 xis S Excisionase from transposon Tn916
KOEHKIND_01684 1.3e-170 L Phage integrase family
KOEHKIND_01685 4e-13 S Membrane
KOEHKIND_01686 3e-246 hemN H Involved in the biosynthesis of porphyrin-containing compound
KOEHKIND_01687 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KOEHKIND_01688 9.9e-34 rpsT J Binds directly to 16S ribosomal RNA
KOEHKIND_01689 1.2e-135 S UPF0126 domain
KOEHKIND_01690 2.7e-99 3.1.4.37 T RNA ligase
KOEHKIND_01691 4e-46 S phosphoesterase or phosphohydrolase
KOEHKIND_01692 2.4e-225 ilvE 2.6.1.42 E Amino-transferase class IV
KOEHKIND_01693 8.3e-95 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KOEHKIND_01694 4.8e-190 S alpha beta
KOEHKIND_01695 2.3e-233 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KOEHKIND_01696 4.4e-44 pntA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
KOEHKIND_01697 1.1e-201 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
KOEHKIND_01698 0.0 fadD 6.2.1.3 I AMP-binding enzyme
KOEHKIND_01699 3.3e-186 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KOEHKIND_01700 2.7e-250 corC S CBS domain
KOEHKIND_01701 7.4e-100 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KOEHKIND_01702 3.4e-197 phoH T PhoH-like protein
KOEHKIND_01703 4.4e-58 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
KOEHKIND_01704 2.1e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KOEHKIND_01706 4e-164 spoU 2.1.1.185 J SpoU rRNA Methylase family
KOEHKIND_01707 4.7e-243 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KOEHKIND_01708 9.7e-106 yitW S Iron-sulfur cluster assembly protein
KOEHKIND_01709 8.8e-101 iscU C SUF system FeS assembly protein, NifU family
KOEHKIND_01710 1.6e-241 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KOEHKIND_01711 1.4e-144 sufC O FeS assembly ATPase SufC
KOEHKIND_01712 2.6e-233 sufD O FeS assembly protein SufD
KOEHKIND_01713 3.6e-290 sufB O FeS assembly protein SufB
KOEHKIND_01714 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KOEHKIND_01715 6.8e-08 3.4.22.70 M Sortase family
KOEHKIND_01716 1.4e-119 K helix_turn_helix, Lux Regulon
KOEHKIND_01717 3.4e-15
KOEHKIND_01718 2.2e-78 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
KOEHKIND_01719 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KOEHKIND_01720 1.6e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KOEHKIND_01721 4.8e-47 3.4.23.43 S Type IV leader peptidase family
KOEHKIND_01722 7.1e-188 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KOEHKIND_01723 3e-75 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KOEHKIND_01724 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KOEHKIND_01725 1.1e-36
KOEHKIND_01726 3.8e-64 WQ51_05790 S Bacterial protein of unknown function (DUF948)
KOEHKIND_01727 1.5e-135 pgm3 G Phosphoglycerate mutase family
KOEHKIND_01728 0.0 oatA I Psort location CytoplasmicMembrane, score 9.99
KOEHKIND_01729 1e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KOEHKIND_01730 1.3e-127 lolD V ABC transporter
KOEHKIND_01731 8.5e-213 V FtsX-like permease family
KOEHKIND_01732 8.2e-64 S Domain of unknown function (DUF4418)
KOEHKIND_01733 0.0 pcrA 3.6.4.12 L DNA helicase
KOEHKIND_01734 0.0 yrhL I Psort location CytoplasmicMembrane, score 9.99
KOEHKIND_01735 3e-107 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KOEHKIND_01736 2.8e-241 pbuX F Permease family
KOEHKIND_01738 1.4e-46 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KOEHKIND_01740 5.6e-112 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
KOEHKIND_01741 2e-39
KOEHKIND_01742 1.1e-26 2.1.1.72 S Adenine-specific methyltransferase EcoRI
KOEHKIND_01743 5.4e-175 tnp7109-21 L Integrase core domain
KOEHKIND_01744 2.8e-46 L Transposase
KOEHKIND_01745 3.5e-64 D MobA/MobL family
KOEHKIND_01746 3.9e-78
KOEHKIND_01748 3.2e-80 L Transposase and inactivated derivatives IS30 family
KOEHKIND_01749 9.5e-35
KOEHKIND_01750 5.1e-07
KOEHKIND_01751 7.1e-103 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KOEHKIND_01752 5.5e-166 S Sucrose-6F-phosphate phosphohydrolase
KOEHKIND_01753 2.1e-94 P ABC-type metal ion transport system permease component
KOEHKIND_01754 2.7e-224 S Peptidase dimerisation domain
KOEHKIND_01755 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KOEHKIND_01756 1.9e-39
KOEHKIND_01757 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
KOEHKIND_01758 3.9e-175 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KOEHKIND_01759 1.3e-113 S Protein of unknown function (DUF3000)
KOEHKIND_01760 2.4e-250 rnd 3.1.13.5 J 3'-5' exonuclease
KOEHKIND_01761 2.8e-236 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KOEHKIND_01762 3.6e-255 clcA_2 P Voltage gated chloride channel
KOEHKIND_01763 1.1e-112 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KOEHKIND_01764 1.5e-127 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KOEHKIND_01765 5.9e-244 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KOEHKIND_01768 1e-234 patB 4.4.1.8 E Aminotransferase, class I II
KOEHKIND_01769 1.2e-225 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KOEHKIND_01770 8.4e-168 fmt2 3.2.2.10 S Belongs to the LOG family
KOEHKIND_01771 1.1e-118 safC S O-methyltransferase
KOEHKIND_01772 4.6e-185 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
KOEHKIND_01773 3e-71 yraN L Belongs to the UPF0102 family
KOEHKIND_01774 1.9e-294 comM O Magnesium chelatase, subunit ChlI C-terminal
KOEHKIND_01775 3.3e-283 dprA 5.99.1.2 LU DNA recombination-mediator protein A
KOEHKIND_01776 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
KOEHKIND_01777 1.5e-166 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
KOEHKIND_01778 2.1e-157 S Putative ABC-transporter type IV
KOEHKIND_01779 2.6e-252 metY 2.5.1.49 E Aminotransferase class-V
KOEHKIND_01780 3.4e-162 V ABC transporter, ATP-binding protein
KOEHKIND_01781 0.0 MV MacB-like periplasmic core domain
KOEHKIND_01782 0.0 phoN I PAP2 superfamily
KOEHKIND_01783 6.1e-132 K helix_turn_helix, Lux Regulon
KOEHKIND_01784 0.0 tcsS2 T Histidine kinase
KOEHKIND_01785 6.5e-265 pip 3.4.11.5 S alpha/beta hydrolase fold
KOEHKIND_01786 6.1e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KOEHKIND_01787 1.3e-168 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
KOEHKIND_01788 3.2e-147 P NLPA lipoprotein
KOEHKIND_01789 5.9e-188 acoA 1.2.4.1 C Dehydrogenase E1 component
KOEHKIND_01790 3.9e-182 1.2.4.1 C Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
KOEHKIND_01791 1.5e-203 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KOEHKIND_01792 2.9e-93 metI P Binding-protein-dependent transport system inner membrane component
KOEHKIND_01793 5.4e-228 mtnE 2.6.1.83 E Aminotransferase class I and II
KOEHKIND_01794 1.2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KOEHKIND_01795 3.1e-194 int L Phage integrase, N-terminal SAM-like domain
KOEHKIND_01796 1.7e-27 S Protein of unknown function (DUF3800)
KOEHKIND_01797 9.7e-30
KOEHKIND_01798 6.8e-08 int L Phage integrase, N-terminal SAM-like domain
KOEHKIND_01799 2.6e-119 dprA LU DNA recombination-mediator protein A
KOEHKIND_01800 3.1e-60 S competence protein
KOEHKIND_01801 3.4e-09
KOEHKIND_01804 4.6e-16

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)