ORF_ID e_value Gene_name EC_number CAZy COGs Description
LHDAJDNO_00001 4.6e-207 pldB 3.1.1.5 I Serine aminopeptidase, S33
LHDAJDNO_00002 7.4e-159 yicL EG EamA-like transporter family
LHDAJDNO_00003 3.4e-103
LHDAJDNO_00005 3.5e-196 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LHDAJDNO_00007 0.0 KL Domain of unknown function (DUF3427)
LHDAJDNO_00008 3e-90 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
LHDAJDNO_00009 1.1e-36 D DivIVA domain protein
LHDAJDNO_00010 9.3e-53 ybjQ S Putative heavy-metal-binding
LHDAJDNO_00011 3.1e-158 I Serine aminopeptidase, S33
LHDAJDNO_00012 2.2e-87 yjcF Q Acetyltransferase (GNAT) domain
LHDAJDNO_00014 1.1e-258 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LHDAJDNO_00015 1.7e-244 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
LHDAJDNO_00016 0.0 cadA P E1-E2 ATPase
LHDAJDNO_00017 2.5e-272 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
LHDAJDNO_00018 3.9e-173 htpX O Belongs to the peptidase M48B family
LHDAJDNO_00020 0.0 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
LHDAJDNO_00021 2.9e-43 S Bacterial mobilisation protein (MobC)
LHDAJDNO_00022 2.3e-127 S Domain of unknown function (DUF4417)
LHDAJDNO_00024 1.9e-61
LHDAJDNO_00025 6.8e-65
LHDAJDNO_00026 3.9e-50 E IrrE N-terminal-like domain
LHDAJDNO_00027 2e-12 E IrrE N-terminal-like domain
LHDAJDNO_00028 4.9e-57 K Cro/C1-type HTH DNA-binding domain
LHDAJDNO_00029 4.5e-252 3.5.1.104 G Polysaccharide deacetylase
LHDAJDNO_00030 3.3e-200 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
LHDAJDNO_00031 1.7e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LHDAJDNO_00032 2.5e-164 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LHDAJDNO_00033 7.3e-59 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LHDAJDNO_00034 2.5e-189 K helix_turn _helix lactose operon repressor
LHDAJDNO_00035 1.5e-74 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
LHDAJDNO_00036 4.5e-297 scrT G Transporter major facilitator family protein
LHDAJDNO_00037 5e-254 yhjE EGP Sugar (and other) transporter
LHDAJDNO_00038 2.8e-204 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LHDAJDNO_00039 4.6e-199 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LHDAJDNO_00040 3.7e-182 gmk 1.1.1.23, 2.7.4.8 S Protein of unknown function (DUF559)
LHDAJDNO_00041 0.0 lacZ 3.2.1.23 G Psort location Cytoplasmic, score 8.87
LHDAJDNO_00042 2.8e-274 aroP E aromatic amino acid transport protein AroP K03293
LHDAJDNO_00043 1e-99 K Transcriptional regulator C-terminal region
LHDAJDNO_00044 2.6e-129 V ABC transporter
LHDAJDNO_00045 0.0 V FtsX-like permease family
LHDAJDNO_00046 8.6e-84 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LHDAJDNO_00047 3e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LHDAJDNO_00048 1.2e-39 E ABC transporter
LHDAJDNO_00049 7.6e-100 bcp 1.11.1.15 O Redoxin
LHDAJDNO_00050 1.1e-157 S Virulence factor BrkB
LHDAJDNO_00051 2.1e-41 XAC3035 O Glutaredoxin
LHDAJDNO_00052 4.8e-48
LHDAJDNO_00054 8.1e-99 L Restriction endonuclease NotI
LHDAJDNO_00055 1.2e-81
LHDAJDNO_00056 2.8e-60 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LHDAJDNO_00057 1.4e-161 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
LHDAJDNO_00058 4.5e-07
LHDAJDNO_00059 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
LHDAJDNO_00060 1.4e-181 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
LHDAJDNO_00061 2e-73 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
LHDAJDNO_00062 1.5e-280 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LHDAJDNO_00063 8.9e-181 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
LHDAJDNO_00064 1.7e-156 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
LHDAJDNO_00065 2.8e-179 pyrD 1.3.1.14 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LHDAJDNO_00066 6.5e-125 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LHDAJDNO_00067 3e-24 K MerR family regulatory protein
LHDAJDNO_00068 8.4e-193 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
LHDAJDNO_00069 1e-127
LHDAJDNO_00070 1.2e-21 KLT Protein tyrosine kinase
LHDAJDNO_00071 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LHDAJDNO_00072 3.3e-242 vbsD V MatE
LHDAJDNO_00073 9.6e-132 S Enoyl-(Acyl carrier protein) reductase
LHDAJDNO_00074 4.3e-132 magIII L endonuclease III
LHDAJDNO_00075 3.8e-93 laaE K Transcriptional regulator PadR-like family
LHDAJDNO_00076 6.8e-176 S Membrane transport protein
LHDAJDNO_00077 2.7e-69 4.1.1.44 S Cupin domain
LHDAJDNO_00078 1.2e-224 hipA 2.7.11.1 S HipA N-terminal domain
LHDAJDNO_00079 3.7e-41 K Helix-turn-helix
LHDAJDNO_00080 1.7e-47 tam 2.1.1.144, 2.1.1.197 FG trans-aconitate 2-methyltransferase activity
LHDAJDNO_00081 3.5e-18
LHDAJDNO_00082 4.2e-101 K Bacterial regulatory proteins, tetR family
LHDAJDNO_00083 4.7e-85 T Domain of unknown function (DUF4234)
LHDAJDNO_00084 1.2e-171 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
LHDAJDNO_00085 1.5e-123 3.8.1.2 S Haloacid dehalogenase-like hydrolase
LHDAJDNO_00086 3.6e-241 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LHDAJDNO_00087 2.4e-54 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LHDAJDNO_00088 1.1e-141 4.1.1.44 S Carboxymuconolactone decarboxylase family
LHDAJDNO_00089 1.2e-88 dkgB S Oxidoreductase, aldo keto reductase family protein
LHDAJDNO_00091 5.1e-289 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
LHDAJDNO_00092 0.0 pafB K WYL domain
LHDAJDNO_00093 1e-51
LHDAJDNO_00094 0.0 helY L DEAD DEAH box helicase
LHDAJDNO_00095 3e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
LHDAJDNO_00096 1.6e-142 pgp 3.1.3.18 S HAD-hyrolase-like
LHDAJDNO_00098 3.6e-90 K Putative zinc ribbon domain
LHDAJDNO_00099 7.2e-126 S GyrI-like small molecule binding domain
LHDAJDNO_00100 3.3e-24 L DNA integration
LHDAJDNO_00101 5.5e-15
LHDAJDNO_00102 7.3e-62
LHDAJDNO_00103 2.7e-120 K helix_turn_helix, mercury resistance
LHDAJDNO_00104 7.3e-74 garA T Inner membrane component of T3SS, cytoplasmic domain
LHDAJDNO_00105 7.7e-141 S Bacterial protein of unknown function (DUF881)
LHDAJDNO_00106 2.6e-31 sbp S Protein of unknown function (DUF1290)
LHDAJDNO_00107 4e-173 S Bacterial protein of unknown function (DUF881)
LHDAJDNO_00108 1.8e-116 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LHDAJDNO_00109 1.8e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
LHDAJDNO_00110 6.4e-41 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
LHDAJDNO_00111 6.3e-101 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
LHDAJDNO_00112 2.3e-192 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LHDAJDNO_00113 4.4e-163 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
LHDAJDNO_00114 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
LHDAJDNO_00115 2.7e-296 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
LHDAJDNO_00116 0.0 M Parallel beta-helix repeats
LHDAJDNO_00117 7.7e-227 M Glycosyl transferase 4-like domain
LHDAJDNO_00118 1.3e-198 ltaE 4.1.2.48 E Beta-eliminating lyase
LHDAJDNO_00120 9.3e-62 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LHDAJDNO_00121 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LHDAJDNO_00122 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LHDAJDNO_00123 4e-231 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LHDAJDNO_00124 0.0 S Esterase-like activity of phytase
LHDAJDNO_00125 9.5e-190 EGP Transmembrane secretion effector
LHDAJDNO_00127 3.3e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LHDAJDNO_00128 1.3e-93 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LHDAJDNO_00129 1.1e-236 carA 6.3.5.5 F Belongs to the CarA family
LHDAJDNO_00130 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
LHDAJDNO_00131 4.8e-301 gmk 2.4.2.10, 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
LHDAJDNO_00132 0.0 S Protein of unknown function DUF262
LHDAJDNO_00133 1.1e-116 K helix_turn_helix, Lux Regulon
LHDAJDNO_00134 8.4e-268 T Histidine kinase
LHDAJDNO_00135 1e-97 S Domain of unknown function (DUF5067)
LHDAJDNO_00136 6.6e-132 ybhL S Belongs to the BI1 family
LHDAJDNO_00137 1.1e-167 ydeD EG EamA-like transporter family
LHDAJDNO_00138 3.2e-121 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
LHDAJDNO_00139 2.1e-279 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LHDAJDNO_00140 9e-185 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LHDAJDNO_00141 1.3e-136 fic D Fic/DOC family
LHDAJDNO_00142 0.0 ftsK D FtsK SpoIIIE family protein
LHDAJDNO_00143 9.2e-124 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LHDAJDNO_00144 1.3e-96 cinA 3.5.1.42 S Belongs to the CinA family
LHDAJDNO_00145 1.6e-80 K Helix-turn-helix XRE-family like proteins
LHDAJDNO_00146 3.7e-40 S Protein of unknown function (DUF3046)
LHDAJDNO_00147 8e-216 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LHDAJDNO_00148 7.1e-74 recX S Modulates RecA activity
LHDAJDNO_00149 1e-07
LHDAJDNO_00151 6.7e-111 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LHDAJDNO_00152 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LHDAJDNO_00153 3e-190 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LHDAJDNO_00154 1.5e-109
LHDAJDNO_00155 1e-133 plsC2 2.3.1.51 I Phosphate acyltransferases
LHDAJDNO_00156 1.7e-180 pknL 2.7.11.1 KLT PASTA
LHDAJDNO_00158 2.3e-133 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
LHDAJDNO_00159 1e-198 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LHDAJDNO_00160 3.2e-99 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LHDAJDNO_00161 5.5e-178 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LHDAJDNO_00162 5.3e-194 galM 5.1.3.3 G Aldose 1-epimerase
LHDAJDNO_00163 5.8e-64
LHDAJDNO_00164 7.1e-125 sigH K Belongs to the sigma-70 factor family. ECF subfamily
LHDAJDNO_00165 1.3e-296 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LHDAJDNO_00166 9.8e-191 V Acetyltransferase (GNAT) domain
LHDAJDNO_00167 4.9e-229 2.6.1.33 M DegT/DnrJ/EryC1/StrS aminotransferase family
LHDAJDNO_00168 9.5e-244 yxbA 6.3.1.12 S ATP-grasp
LHDAJDNO_00169 7.4e-129 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
LHDAJDNO_00170 0.0 smc D Required for chromosome condensation and partitioning
LHDAJDNO_00171 2e-289 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
LHDAJDNO_00173 2.1e-96 3.6.1.55 F NUDIX domain
LHDAJDNO_00174 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
LHDAJDNO_00175 0.0 P Belongs to the ABC transporter superfamily
LHDAJDNO_00176 3.3e-190 dppC EP Binding-protein-dependent transport system inner membrane component
LHDAJDNO_00177 2e-184 dppB EP Binding-protein-dependent transport system inner membrane component
LHDAJDNO_00178 2.2e-304 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
LHDAJDNO_00179 9.6e-244 nagA 3.5.1.25 G Amidohydrolase family
LHDAJDNO_00180 6.6e-153 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LHDAJDNO_00181 2.6e-216 GK ROK family
LHDAJDNO_00182 3.4e-132 cutC P Participates in the control of copper homeostasis
LHDAJDNO_00183 9e-223 GK ROK family
LHDAJDNO_00184 1.9e-169 2.7.1.4 G pfkB family carbohydrate kinase
LHDAJDNO_00185 4.4e-236 G Major Facilitator Superfamily
LHDAJDNO_00186 6.6e-85 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LHDAJDNO_00188 1.3e-37
LHDAJDNO_00189 4.7e-158 ftsQ 6.3.2.4 D Cell division protein FtsQ
LHDAJDNO_00190 1.8e-295 murC 6.3.2.8 M Belongs to the MurCDEF family
LHDAJDNO_00191 1.7e-218 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LHDAJDNO_00192 9.6e-226 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
LHDAJDNO_00193 1.2e-266 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LHDAJDNO_00194 3.6e-202 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LHDAJDNO_00195 1.3e-282 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LHDAJDNO_00196 2.8e-180 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LHDAJDNO_00197 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
LHDAJDNO_00198 2.3e-23 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LHDAJDNO_00199 1.3e-215 MA20_36090 S Psort location Cytoplasmic, score 8.87
LHDAJDNO_00200 3.4e-252 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
LHDAJDNO_00201 9.3e-36 1.1.1.122, 1.1.1.65 C Aldo/keto reductase family
LHDAJDNO_00202 9.5e-75 EGP Major facilitator superfamily
LHDAJDNO_00203 5.2e-10 K Winged helix DNA-binding domain
LHDAJDNO_00204 3.7e-179 glkA 2.7.1.2 G ROK family
LHDAJDNO_00205 3.5e-299 S ATPases associated with a variety of cellular activities
LHDAJDNO_00206 3.7e-16 EGP Major facilitator Superfamily
LHDAJDNO_00207 3.7e-159 I alpha/beta hydrolase fold
LHDAJDNO_00208 2.3e-113 S Pyridoxamine 5'-phosphate oxidase
LHDAJDNO_00210 5.2e-61 S DUF218 domain
LHDAJDNO_00211 6.6e-34 S DUF218 domain
LHDAJDNO_00212 5e-13 S Protein of unknown function (DUF979)
LHDAJDNO_00213 4.4e-115 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LHDAJDNO_00214 2e-126
LHDAJDNO_00215 7.6e-153 M domain, Protein
LHDAJDNO_00216 2.4e-306 yjjK S ATP-binding cassette protein, ChvD family
LHDAJDNO_00217 0.0 3.2.1.52, 3.2.1.83 GH16,GH20 G hydrolase family 20, catalytic
LHDAJDNO_00218 2.1e-171 tesB I Thioesterase-like superfamily
LHDAJDNO_00219 1.9e-76 S Protein of unknown function (DUF3180)
LHDAJDNO_00220 1.4e-292 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LHDAJDNO_00221 2.3e-164 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LHDAJDNO_00222 4.5e-100 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
LHDAJDNO_00223 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LHDAJDNO_00224 9.4e-98 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
LHDAJDNO_00225 2.3e-212 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LHDAJDNO_00226 4.5e-261 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
LHDAJDNO_00227 5e-309
LHDAJDNO_00228 1.7e-168 natA V ATPases associated with a variety of cellular activities
LHDAJDNO_00229 6.3e-232 epsG M Glycosyl transferase family 21
LHDAJDNO_00230 5.7e-273 S AI-2E family transporter
LHDAJDNO_00231 4.3e-177 3.4.14.13 M Glycosyltransferase like family 2
LHDAJDNO_00232 8.1e-205 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
LHDAJDNO_00235 5.7e-68 S Domain of unknown function (DUF4190)
LHDAJDNO_00236 6.9e-200 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LHDAJDNO_00237 1.8e-175 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LHDAJDNO_00239 1.7e-268 lacS G Psort location CytoplasmicMembrane, score 10.00
LHDAJDNO_00240 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
LHDAJDNO_00241 2.8e-198 3.2.1.18 GH33 E GDSL-like Lipase/Acylhydrolase
LHDAJDNO_00242 4.7e-140 S HAD hydrolase, family IA, variant 3
LHDAJDNO_00244 7.7e-126 dedA S SNARE associated Golgi protein
LHDAJDNO_00245 2.6e-167 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LHDAJDNO_00246 8.6e-59
LHDAJDNO_00247 3.6e-130
LHDAJDNO_00248 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LHDAJDNO_00249 4.8e-85 K Transcriptional regulator
LHDAJDNO_00251 4e-38 xylR 5.3.1.12 G MFS/sugar transport protein
LHDAJDNO_00252 1.6e-213 xylR 5.3.1.12 G MFS/sugar transport protein
LHDAJDNO_00253 2.8e-15 G MFS/sugar transport protein
LHDAJDNO_00254 5.9e-185 tatD L TatD related DNase
LHDAJDNO_00255 0.0 kup P Transport of potassium into the cell
LHDAJDNO_00256 3.3e-166 S Glutamine amidotransferase domain
LHDAJDNO_00257 2.1e-137 T HD domain
LHDAJDNO_00258 6e-180 V ABC transporter
LHDAJDNO_00259 1.1e-246 V ABC transporter permease
LHDAJDNO_00260 0.0 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
LHDAJDNO_00261 0.0 S Psort location Cytoplasmic, score 8.87
LHDAJDNO_00262 1.9e-164 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
LHDAJDNO_00263 8.7e-27 thiS 2.8.1.10 H ThiS family
LHDAJDNO_00265 5.2e-262
LHDAJDNO_00266 4.7e-207 S Glycosyltransferase, group 2 family protein
LHDAJDNO_00267 2.2e-57 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
LHDAJDNO_00268 6.7e-41 cbiM P PDGLE domain
LHDAJDNO_00269 5e-91
LHDAJDNO_00270 6.3e-201 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
LHDAJDNO_00271 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LHDAJDNO_00272 7.7e-129 cpaE D bacterial-type flagellum organization
LHDAJDNO_00273 3.4e-191 cpaF U Type II IV secretion system protein
LHDAJDNO_00274 5.7e-121 U Type ii secretion system
LHDAJDNO_00275 9.5e-79 gspF NU Type II secretion system (T2SS), protein F
LHDAJDNO_00276 3.2e-41 S Protein of unknown function (DUF4244)
LHDAJDNO_00277 4.8e-55 U TadE-like protein
LHDAJDNO_00278 3.1e-57 S TIGRFAM helicase secretion neighborhood TadE-like protein
LHDAJDNO_00279 3.7e-215 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
LHDAJDNO_00280 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
LHDAJDNO_00281 6.7e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LHDAJDNO_00282 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
LHDAJDNO_00283 3.8e-92 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
LHDAJDNO_00284 0.0 comE S Competence protein
LHDAJDNO_00285 4.8e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
LHDAJDNO_00286 3.8e-119 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
LHDAJDNO_00287 1e-159 yeaZ 2.3.1.234 O Glycoprotease family
LHDAJDNO_00288 3.2e-101 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
LHDAJDNO_00289 6.2e-196 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LHDAJDNO_00291 3.3e-129 M Peptidase family M23
LHDAJDNO_00292 0.0 fadD1 6.2.1.3 I AMP-binding enzyme
LHDAJDNO_00293 2.3e-274 G ABC transporter substrate-binding protein
LHDAJDNO_00294 3.3e-241 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
LHDAJDNO_00295 2.5e-200 guaB 1.1.1.205 F IMP dehydrogenase family protein
LHDAJDNO_00296 3.4e-91
LHDAJDNO_00297 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
LHDAJDNO_00298 1.7e-87 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LHDAJDNO_00299 9.7e-29 rpsB J Belongs to the universal ribosomal protein uS2 family
LHDAJDNO_00300 4.4e-98 rpsB J Belongs to the universal ribosomal protein uS2 family
LHDAJDNO_00301 4.8e-146 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LHDAJDNO_00302 1e-127 3.2.1.8 S alpha beta
LHDAJDNO_00303 2.4e-133 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
LHDAJDNO_00304 8.9e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LHDAJDNO_00305 1.8e-176 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
LHDAJDNO_00306 1e-226 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
LHDAJDNO_00307 1.4e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
LHDAJDNO_00308 5.3e-74 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LHDAJDNO_00309 5.1e-306 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LHDAJDNO_00310 4.3e-247 G Bacterial extracellular solute-binding protein
LHDAJDNO_00311 1.1e-173 G Binding-protein-dependent transport system inner membrane component
LHDAJDNO_00312 1.1e-167 G ABC transporter permease
LHDAJDNO_00313 1.1e-155 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
LHDAJDNO_00314 5.2e-63 psp1 3.5.99.10 J Endoribonuclease L-PSP
LHDAJDNO_00315 6.8e-181 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
LHDAJDNO_00316 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
LHDAJDNO_00317 1e-306 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LHDAJDNO_00318 1.9e-81 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
LHDAJDNO_00319 2.9e-290 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
LHDAJDNO_00320 5.2e-240 hom 1.1.1.3 E Homoserine dehydrogenase
LHDAJDNO_00321 3.5e-188 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LHDAJDNO_00322 8.1e-279 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
LHDAJDNO_00323 4.9e-66
LHDAJDNO_00324 2.1e-58
LHDAJDNO_00325 1.6e-163 V ATPases associated with a variety of cellular activities
LHDAJDNO_00326 3.3e-256 V Efflux ABC transporter, permease protein
LHDAJDNO_00327 4.4e-147 mdcF S Transporter, auxin efflux carrier (AEC) family protein
LHDAJDNO_00328 6.6e-237 dapE 3.5.1.18 E Peptidase dimerisation domain
LHDAJDNO_00329 0.0 rne 3.1.26.12 J Ribonuclease E/G family
LHDAJDNO_00330 3.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
LHDAJDNO_00331 3.1e-40 rpmA J Ribosomal L27 protein
LHDAJDNO_00332 7.5e-216 K Psort location Cytoplasmic, score
LHDAJDNO_00333 3.7e-299 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LHDAJDNO_00334 4.1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LHDAJDNO_00335 4e-231 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
LHDAJDNO_00337 1.1e-31 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LHDAJDNO_00338 1.2e-128 nusG K Participates in transcription elongation, termination and antitermination
LHDAJDNO_00339 8.2e-173 plsC2 2.3.1.51 I Phosphate acyltransferases
LHDAJDNO_00340 2.5e-178 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
LHDAJDNO_00341 2.2e-218 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
LHDAJDNO_00342 3.7e-201 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
LHDAJDNO_00343 0.0 3.2.1.97 GH101 G Glycosyl hydrolase 101 beta sandwich domain
LHDAJDNO_00344 6.9e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LHDAJDNO_00345 1.7e-174 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LHDAJDNO_00346 3.6e-45
LHDAJDNO_00347 1.6e-145 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LHDAJDNO_00348 9.1e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LHDAJDNO_00350 2.1e-263 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LHDAJDNO_00351 1.2e-68 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LHDAJDNO_00352 1.9e-138 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
LHDAJDNO_00353 1.1e-77 S Bacterial PH domain
LHDAJDNO_00354 1.6e-251 nplT 3.2.1.1 GH13 G Alpha amylase, catalytic domain
LHDAJDNO_00356 1.2e-108
LHDAJDNO_00357 5e-133 C Putative TM nitroreductase
LHDAJDNO_00358 2.2e-141 yijF S Domain of unknown function (DUF1287)
LHDAJDNO_00359 4.6e-70 pdxH S Pfam:Pyridox_oxidase
LHDAJDNO_00360 1.4e-139 KT RESPONSE REGULATOR receiver
LHDAJDNO_00361 8.2e-193 V VanZ like family
LHDAJDNO_00362 2.5e-109 ycaK 1.6.5.2 S NADPH-dependent FMN reductase
LHDAJDNO_00363 8.6e-96 ypjC S Putative ABC-transporter type IV
LHDAJDNO_00364 9.8e-158
LHDAJDNO_00366 2.9e-99 EGP Major facilitator Superfamily
LHDAJDNO_00367 3e-28 EGP Major facilitator Superfamily
LHDAJDNO_00368 9.8e-164 rpoC M heme binding
LHDAJDNO_00369 7.3e-80 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LHDAJDNO_00370 5.6e-29
LHDAJDNO_00371 3.2e-43
LHDAJDNO_00372 7.9e-131 S SOS response associated peptidase (SRAP)
LHDAJDNO_00373 5.1e-23 qseC 2.7.13.3 T Histidine kinase
LHDAJDNO_00374 2.3e-184 S Acetyltransferase (GNAT) domain
LHDAJDNO_00376 1.3e-100 XK27_07525 3.6.1.55 F Hydrolase of X-linked nucleoside diphosphate N terminal
LHDAJDNO_00377 4.3e-56 K Transcriptional regulator
LHDAJDNO_00378 1.2e-97 MA20_25245 K FR47-like protein
LHDAJDNO_00379 1.5e-120 ydaF_1 J Acetyltransferase (GNAT) domain
LHDAJDNO_00380 2.4e-62 yeaO K Protein of unknown function, DUF488
LHDAJDNO_00381 1.3e-162 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LHDAJDNO_00382 8.8e-284 S Psort location Cytoplasmic, score 8.87
LHDAJDNO_00383 1e-108 S Domain of unknown function (DUF4194)
LHDAJDNO_00384 0.0 S Psort location Cytoplasmic, score 8.87
LHDAJDNO_00385 4.5e-299 E Serine carboxypeptidase
LHDAJDNO_00386 3.6e-162 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
LHDAJDNO_00387 3.7e-171 corA P CorA-like Mg2+ transporter protein
LHDAJDNO_00388 2.6e-169 ET Bacterial periplasmic substrate-binding proteins
LHDAJDNO_00389 4.3e-143 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
LHDAJDNO_00390 8.4e-200 sprF 4.6.1.1 M Cell surface antigen C-terminus
LHDAJDNO_00391 8.9e-26
LHDAJDNO_00392 3.3e-139
LHDAJDNO_00393 1e-62 S PrgI family protein
LHDAJDNO_00394 0.0 trsE U type IV secretory pathway VirB4
LHDAJDNO_00395 6.4e-206 isp2 3.2.1.96 M CHAP domain
LHDAJDNO_00396 3.6e-14 U Type IV secretory system Conjugative DNA transfer
LHDAJDNO_00397 5.1e-119
LHDAJDNO_00399 1.1e-100 K Helix-turn-helix domain protein
LHDAJDNO_00402 0.0 U Type IV secretory system Conjugative DNA transfer
LHDAJDNO_00403 9.3e-31
LHDAJDNO_00404 3.2e-39
LHDAJDNO_00405 0.0 XK27_00500 KL Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LHDAJDNO_00408 2e-275
LHDAJDNO_00409 2.5e-168 S Protein of unknown function (DUF3801)
LHDAJDNO_00410 4.4e-305 ltrBE1 U Relaxase/Mobilisation nuclease domain
LHDAJDNO_00411 4.9e-66 S Bacterial mobilisation protein (MobC)
LHDAJDNO_00412 3.6e-41 S Protein of unknown function (DUF2442)
LHDAJDNO_00413 8.8e-55
LHDAJDNO_00414 1.3e-87
LHDAJDNO_00415 0.0 topB 5.99.1.2 L DNA topoisomerase
LHDAJDNO_00416 5e-82
LHDAJDNO_00417 9.4e-60
LHDAJDNO_00418 5.8e-48
LHDAJDNO_00419 1e-232 S HipA-like C-terminal domain
LHDAJDNO_00420 3.4e-112 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LHDAJDNO_00421 3.8e-139 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
LHDAJDNO_00422 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
LHDAJDNO_00423 3.7e-109
LHDAJDNO_00424 9e-97 S Protein of unknown function (DUF4230)
LHDAJDNO_00425 1.4e-116 mug 3.2.2.28 L Uracil DNA glycosylase superfamily
LHDAJDNO_00426 8.9e-33 K DNA-binding transcription factor activity
LHDAJDNO_00427 1.8e-68 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LHDAJDNO_00428 2e-32
LHDAJDNO_00429 2.8e-304 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
LHDAJDNO_00430 5.1e-292 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LHDAJDNO_00431 2e-186 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
LHDAJDNO_00432 5e-240 purD 6.3.4.13 F Belongs to the GARS family
LHDAJDNO_00433 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
LHDAJDNO_00434 1e-246 S Putative esterase
LHDAJDNO_00435 0.0 lysX S Uncharacterised conserved protein (DUF2156)
LHDAJDNO_00437 1.3e-162 P Zinc-uptake complex component A periplasmic
LHDAJDNO_00438 1.8e-139 S cobalamin synthesis protein
LHDAJDNO_00439 2.6e-46 rpmB J Ribosomal L28 family
LHDAJDNO_00440 7.5e-49 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LHDAJDNO_00441 5.7e-42 rpmE2 J Ribosomal protein L31
LHDAJDNO_00442 8.2e-15 rpmJ J Ribosomal protein L36
LHDAJDNO_00443 2.3e-23 J Ribosomal L32p protein family
LHDAJDNO_00444 2e-200 ycgR S Predicted permease
LHDAJDNO_00445 2.6e-154 S TIGRFAM TIGR03943 family protein
LHDAJDNO_00446 2.6e-45
LHDAJDNO_00447 4.3e-73 zur P Belongs to the Fur family
LHDAJDNO_00448 6.2e-229 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LHDAJDNO_00449 4.7e-85 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LHDAJDNO_00450 4.5e-180 adh3 C Zinc-binding dehydrogenase
LHDAJDNO_00451 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LHDAJDNO_00453 5.3e-44 S Memo-like protein
LHDAJDNO_00454 1.9e-25 K Putative ATP-dependent DNA helicase recG C-terminal
LHDAJDNO_00455 0.0
LHDAJDNO_00456 8.6e-245 U Sodium:dicarboxylate symporter family
LHDAJDNO_00457 1.1e-119 rsmD 2.1.1.171 L Conserved hypothetical protein 95
LHDAJDNO_00458 2.6e-106 XK27_02070 S Nitroreductase family
LHDAJDNO_00459 3.4e-82 hsp20 O Hsp20/alpha crystallin family
LHDAJDNO_00460 9.2e-165 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
LHDAJDNO_00461 1.3e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LHDAJDNO_00462 1.8e-34 CP_0960 S Belongs to the UPF0109 family
LHDAJDNO_00463 1e-54 rpsP J Belongs to the bacterial ribosomal protein bS16 family
LHDAJDNO_00464 1.5e-294 ydfD EK Alanine-glyoxylate amino-transferase
LHDAJDNO_00465 1.3e-93 argO S LysE type translocator
LHDAJDNO_00466 1.9e-222 S Endonuclease/Exonuclease/phosphatase family
LHDAJDNO_00467 8.4e-272 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LHDAJDNO_00468 1.4e-164 P Cation efflux family
LHDAJDNO_00469 0.0 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
LHDAJDNO_00470 1.1e-135 guaA1 6.3.5.2 F Peptidase C26
LHDAJDNO_00471 0.0 yjjK S ABC transporter
LHDAJDNO_00472 2e-58 S Protein of unknown function (DUF3039)
LHDAJDNO_00473 1e-81 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LHDAJDNO_00474 3.6e-107
LHDAJDNO_00475 2.3e-113 yceD S Uncharacterized ACR, COG1399
LHDAJDNO_00476 2.3e-19 rpmF J Belongs to the bacterial ribosomal protein bL32 family
LHDAJDNO_00477 6.1e-140 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LHDAJDNO_00478 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
LHDAJDNO_00479 2.9e-91 ilvN 2.2.1.6 E ACT domain
LHDAJDNO_00481 7.5e-247 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LHDAJDNO_00482 2.1e-134 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LHDAJDNO_00483 1.7e-117 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LHDAJDNO_00484 2.4e-176 S Auxin Efflux Carrier
LHDAJDNO_00487 0.0 pgi 5.3.1.9 G Belongs to the GPI family
LHDAJDNO_00488 5.6e-190
LHDAJDNO_00490 6.9e-201
LHDAJDNO_00492 5.5e-122 mgtC S MgtC family
LHDAJDNO_00493 0.0 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
LHDAJDNO_00494 2.4e-24 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
LHDAJDNO_00495 2.7e-261 abcT3 P ATPases associated with a variety of cellular activities
LHDAJDNO_00496 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
LHDAJDNO_00497 1.4e-173 K Putative sugar-binding domain
LHDAJDNO_00498 8.8e-213 gatC G PTS system sugar-specific permease component
LHDAJDNO_00499 8e-293 2.7.1.53 G FGGY family of carbohydrate kinases, C-terminal domain
LHDAJDNO_00500 3.1e-172 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
LHDAJDNO_00501 3.3e-129 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
LHDAJDNO_00502 5.6e-62 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LHDAJDNO_00503 4.4e-157 lepB 3.4.21.89 U Belongs to the peptidase S26 family
LHDAJDNO_00504 2.5e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LHDAJDNO_00505 3e-201 K helix_turn _helix lactose operon repressor
LHDAJDNO_00506 0.0 fadD 6.2.1.3 I AMP-binding enzyme
LHDAJDNO_00507 6.9e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LHDAJDNO_00508 1.3e-111 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LHDAJDNO_00511 1.9e-173 G Glycosyl hydrolases family 43
LHDAJDNO_00512 6.5e-107 G Glycosyl hydrolases family 43
LHDAJDNO_00513 2.1e-202 K helix_turn _helix lactose operon repressor
LHDAJDNO_00514 9.3e-11 3.2.1.14 GH18 EM Domain of unknown function (DUF5011)
LHDAJDNO_00515 2.9e-170 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
LHDAJDNO_00516 2.1e-134 L Protein of unknown function (DUF1524)
LHDAJDNO_00517 4.7e-225 mntH P H( )-stimulated, divalent metal cation uptake system
LHDAJDNO_00518 1.5e-305 EGP Major facilitator Superfamily
LHDAJDNO_00519 7.7e-144 rfbP 2.7.8.6 M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
LHDAJDNO_00520 7.1e-94 lacG G Binding-protein-dependent transport system inner membrane component
LHDAJDNO_00521 4.7e-109 M1-530 S Protein of unknown function (DUF4127)
LHDAJDNO_00522 1.3e-57 2.7.1.2 GK ROK family
LHDAJDNO_00523 4.9e-85 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
LHDAJDNO_00526 2.9e-87 topB 5.99.1.2 L DNA topoisomerase
LHDAJDNO_00527 5.7e-88 topB 5.99.1.2 L DNA topoisomerase
LHDAJDNO_00530 3.6e-69
LHDAJDNO_00531 6e-58 S pathogenesis
LHDAJDNO_00532 5.8e-35 L Psort location Cytoplasmic, score 8.87
LHDAJDNO_00533 6.3e-164 tnp7109-2 L PFAM Transposase, Mutator family
LHDAJDNO_00534 2e-102 L Integrase core domain
LHDAJDNO_00535 1.4e-12 L Transposase
LHDAJDNO_00536 4.1e-104 K cell envelope-related transcriptional attenuator
LHDAJDNO_00538 2.2e-224
LHDAJDNO_00539 5e-179 S G5
LHDAJDNO_00540 2.5e-59 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
LHDAJDNO_00541 4.8e-119 F Domain of unknown function (DUF4916)
LHDAJDNO_00542 2.6e-160 mhpC I Alpha/beta hydrolase family
LHDAJDNO_00543 3.1e-206 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
LHDAJDNO_00544 0.0 enhA_2 S L,D-transpeptidase catalytic domain
LHDAJDNO_00545 4.9e-72 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
LHDAJDNO_00546 7.7e-239 S Uncharacterized conserved protein (DUF2183)
LHDAJDNO_00547 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
LHDAJDNO_00548 2.4e-192 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
LHDAJDNO_00549 5.8e-120 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
LHDAJDNO_00550 1.6e-134 glxR K helix_turn_helix, cAMP Regulatory protein
LHDAJDNO_00551 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
LHDAJDNO_00552 6.3e-218 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
LHDAJDNO_00553 6.7e-227 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
LHDAJDNO_00554 3.1e-139 glpR K DeoR C terminal sensor domain
LHDAJDNO_00555 3.3e-252 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
LHDAJDNO_00556 9.9e-233 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
LHDAJDNO_00557 8.6e-243 EGP Sugar (and other) transporter
LHDAJDNO_00558 4.2e-43 gcvR T Belongs to the UPF0237 family
LHDAJDNO_00559 1e-251 S UPF0210 protein
LHDAJDNO_00560 1.9e-72
LHDAJDNO_00562 6.3e-122 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LHDAJDNO_00563 6.3e-51 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G Putative cell wall binding repeat
LHDAJDNO_00564 5.8e-187 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
LHDAJDNO_00565 1.4e-105
LHDAJDNO_00566 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LHDAJDNO_00567 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LHDAJDNO_00568 7.2e-95 T Forkhead associated domain
LHDAJDNO_00569 2.8e-68 B Belongs to the OprB family
LHDAJDNO_00570 2e-166 3.1.3.16 T Sigma factor PP2C-like phosphatases
LHDAJDNO_00571 0.0 E Transglutaminase-like superfamily
LHDAJDNO_00572 1.7e-230 S Protein of unknown function DUF58
LHDAJDNO_00573 3.9e-232 S ATPase family associated with various cellular activities (AAA)
LHDAJDNO_00574 0.0 S Fibronectin type 3 domain
LHDAJDNO_00575 5.2e-270 KLT Protein tyrosine kinase
LHDAJDNO_00576 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
LHDAJDNO_00577 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
LHDAJDNO_00578 8.6e-159 K -acetyltransferase
LHDAJDNO_00579 1.3e-257 G Major Facilitator Superfamily
LHDAJDNO_00580 2.9e-66 gsiA P ATPase activity
LHDAJDNO_00581 6.5e-43 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
LHDAJDNO_00582 2.7e-10 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
LHDAJDNO_00583 6.4e-24 relB L RelB antitoxin
LHDAJDNO_00584 1.4e-59 L Transposase
LHDAJDNO_00585 1e-132 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LHDAJDNO_00586 1.9e-161 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LHDAJDNO_00587 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LHDAJDNO_00588 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
LHDAJDNO_00589 7.7e-204 O Subtilase family
LHDAJDNO_00590 1.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LHDAJDNO_00591 1.2e-123 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LHDAJDNO_00592 3.6e-271 S zinc finger
LHDAJDNO_00593 2.5e-101 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
LHDAJDNO_00594 2.9e-229 aspB E Aminotransferase class-V
LHDAJDNO_00595 6.9e-157 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
LHDAJDNO_00596 2.7e-132 tmp1 S Domain of unknown function (DUF4391)
LHDAJDNO_00597 2.6e-149 moeB 2.7.7.80 H ThiF family
LHDAJDNO_00598 1.8e-256 cdr OP Sulfurtransferase TusA
LHDAJDNO_00599 4e-181 iunH1 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
LHDAJDNO_00601 1.5e-169 S Endonuclease/Exonuclease/phosphatase family
LHDAJDNO_00602 2.3e-42 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LHDAJDNO_00603 3e-270 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LHDAJDNO_00604 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
LHDAJDNO_00605 9.4e-50 L Single-strand binding protein family
LHDAJDNO_00606 2.4e-170
LHDAJDNO_00607 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LHDAJDNO_00608 7.9e-185 phoN I PAP2 superfamily
LHDAJDNO_00609 7.4e-39 GT87 NU Tfp pilus assembly protein FimV
LHDAJDNO_00610 3.9e-270 recD2 3.6.4.12 L PIF1-like helicase
LHDAJDNO_00611 8.4e-159 supH S Sucrose-6F-phosphate phosphohydrolase
LHDAJDNO_00612 4.1e-121 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
LHDAJDNO_00613 1.4e-109 KT Transcriptional regulatory protein, C terminal
LHDAJDNO_00614 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
LHDAJDNO_00615 4.1e-289 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
LHDAJDNO_00616 6.2e-192 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
LHDAJDNO_00617 5.2e-116 ywlC 2.7.7.87 J Belongs to the SUA5 family
LHDAJDNO_00618 2.4e-55 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
LHDAJDNO_00619 3e-184 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LHDAJDNO_00620 6.5e-188 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LHDAJDNO_00621 3.9e-36 rpmE J Binds the 23S rRNA
LHDAJDNO_00623 1.8e-21 K helix_turn_helix, arabinose operon control protein
LHDAJDNO_00624 3.6e-44 K helix_turn_helix, arabinose operon control protein
LHDAJDNO_00625 9.5e-68 K helix_turn_helix, arabinose operon control protein
LHDAJDNO_00626 2.8e-163 glcU G Sugar transport protein
LHDAJDNO_00627 1.3e-177 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
LHDAJDNO_00628 7.1e-258 cma 2.1.1.79 M Mycolic acid cyclopropane synthetase
LHDAJDNO_00629 1.5e-108
LHDAJDNO_00630 8.3e-170 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
LHDAJDNO_00631 1.6e-141 3.5.2.6 V Beta-lactamase enzyme family
LHDAJDNO_00632 1.9e-139 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
LHDAJDNO_00633 4.6e-163 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
LHDAJDNO_00634 4.2e-164 EG EamA-like transporter family
LHDAJDNO_00636 8.7e-146 V FtsX-like permease family
LHDAJDNO_00637 1.5e-147 S Sulfite exporter TauE/SafE
LHDAJDNO_00639 1.4e-218 ykiI
LHDAJDNO_00640 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
LHDAJDNO_00641 1.4e-119 3.6.1.13 L NUDIX domain
LHDAJDNO_00642 3.2e-172 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
LHDAJDNO_00643 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LHDAJDNO_00644 9.2e-120 pdtaR T Response regulator receiver domain protein
LHDAJDNO_00646 3.3e-109 aspA 3.6.1.13 L NUDIX domain
LHDAJDNO_00647 6.6e-273 pyk 2.7.1.40 G Pyruvate kinase
LHDAJDNO_00648 1.3e-179 terC P Integral membrane protein, TerC family
LHDAJDNO_00649 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LHDAJDNO_00650 4.5e-106 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LHDAJDNO_00651 3e-43 rpsA J Ribosomal protein S1
LHDAJDNO_00652 2.8e-185 rpsA J Ribosomal protein S1
LHDAJDNO_00653 1.8e-164 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LHDAJDNO_00654 3.7e-172 P Zinc-uptake complex component A periplasmic
LHDAJDNO_00655 1.8e-164 znuC P ATPases associated with a variety of cellular activities
LHDAJDNO_00656 2.5e-131 znuB U ABC 3 transport family
LHDAJDNO_00657 8.5e-84 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
LHDAJDNO_00658 5.1e-102 carD K CarD-like/TRCF domain
LHDAJDNO_00659 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LHDAJDNO_00660 1.9e-127 T Response regulator receiver domain protein
LHDAJDNO_00661 4.3e-203 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
LHDAJDNO_00662 2.1e-72 rulA 3.4.21.88 KT Peptidase S24-like
LHDAJDNO_00663 1.4e-130 ctsW S Phosphoribosyl transferase domain
LHDAJDNO_00664 3.4e-157 cof 5.2.1.8 T Eukaryotic phosphomannomutase
LHDAJDNO_00665 6.3e-66 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
LHDAJDNO_00666 3.6e-261
LHDAJDNO_00667 0.0 S Glycosyl transferase, family 2
LHDAJDNO_00668 5.8e-54 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
LHDAJDNO_00669 8.7e-142 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
LHDAJDNO_00670 2.1e-260 nox 1.6.3.4 C Pyridine nucleotide-disulphide oxidoreductase
LHDAJDNO_00671 4.4e-233 metC 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
LHDAJDNO_00672 1.5e-244 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
LHDAJDNO_00673 1.9e-124 XK27_08050 O prohibitin homologues
LHDAJDNO_00674 7.9e-274 aldH 1.2.1.3, 1.2.1.5 C Aldehyde dehydrogenase family
LHDAJDNO_00675 5e-55 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
LHDAJDNO_00676 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LHDAJDNO_00678 0.0 3.2.1.51 GH29 G Alpha-L-fucosidase
LHDAJDNO_00679 7.7e-21 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
LHDAJDNO_00680 1.9e-189 K Periplasmic binding protein domain
LHDAJDNO_00681 5.5e-124 G ABC transporter permease
LHDAJDNO_00682 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
LHDAJDNO_00683 1.1e-63 G carbohydrate transport
LHDAJDNO_00684 8.8e-278 G Bacterial extracellular solute-binding protein
LHDAJDNO_00685 3.6e-143 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LHDAJDNO_00686 1.8e-309 E ABC transporter, substrate-binding protein, family 5
LHDAJDNO_00687 1.6e-169 P Binding-protein-dependent transport system inner membrane component
LHDAJDNO_00688 2.9e-163 EP Binding-protein-dependent transport system inner membrane component
LHDAJDNO_00689 5.2e-142 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
LHDAJDNO_00690 4.4e-155 sapF E ATPases associated with a variety of cellular activities
LHDAJDNO_00691 1.9e-189 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LHDAJDNO_00692 1.5e-156 K Putative DNA-binding domain
LHDAJDNO_00693 1.1e-27 3.1.21.3 V type I restriction enzyme
LHDAJDNO_00694 4.1e-239 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
LHDAJDNO_00695 1.1e-84 argR K Regulates arginine biosynthesis genes
LHDAJDNO_00696 1.6e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LHDAJDNO_00697 1.9e-247 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
LHDAJDNO_00698 1.7e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
LHDAJDNO_00699 1.3e-215 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LHDAJDNO_00700 2.2e-204 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LHDAJDNO_00701 5.1e-87
LHDAJDNO_00702 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
LHDAJDNO_00703 3.1e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LHDAJDNO_00704 4.6e-160 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LHDAJDNO_00705 6.9e-136 ybbL V ATPases associated with a variety of cellular activities
LHDAJDNO_00706 2.1e-135 ybbM V Uncharacterised protein family (UPF0014)
LHDAJDNO_00707 3.7e-51 IQ oxidoreductase activity
LHDAJDNO_00709 1.2e-74 K AraC-like ligand binding domain
LHDAJDNO_00710 6.9e-237 rutG F Permease family
LHDAJDNO_00711 1.1e-158 3.1.3.73 G Phosphoglycerate mutase family
LHDAJDNO_00712 4.2e-63 S Phospholipase/Carboxylesterase
LHDAJDNO_00713 3.1e-187 MA20_14895 S Conserved hypothetical protein 698
LHDAJDNO_00714 6.6e-145 rlrG K Bacterial regulatory helix-turn-helix protein, lysR family
LHDAJDNO_00715 8.4e-119 3.1.3.27 E haloacid dehalogenase-like hydrolase
LHDAJDNO_00716 1.7e-287 2.4.1.166 GT2 M Glycosyltransferase like family 2
LHDAJDNO_00718 0.0 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
LHDAJDNO_00719 1.7e-104 ypfH S Phospholipase/Carboxylesterase
LHDAJDNO_00720 2.7e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
LHDAJDNO_00721 1.1e-24
LHDAJDNO_00722 2.1e-34 yhcC S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
LHDAJDNO_00723 4.8e-225 G Transmembrane secretion effector
LHDAJDNO_00724 9.8e-255 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LHDAJDNO_00725 3.6e-221 pyrD 1.3.1.14 F Dihydroorotate dehydrogenase
LHDAJDNO_00726 9.2e-182 S CAAX protease self-immunity
LHDAJDNO_00728 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
LHDAJDNO_00729 3.8e-133 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LHDAJDNO_00730 2.2e-273 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LHDAJDNO_00731 2.8e-138 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
LHDAJDNO_00732 4.4e-252 S Calcineurin-like phosphoesterase
LHDAJDNO_00735 5.7e-43 S Domain of unknown function (DUF4143)
LHDAJDNO_00736 3.1e-95 S Domain of unknown function (DUF4143)
LHDAJDNO_00737 1.1e-275 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LHDAJDNO_00739 3.1e-124 S HAD hydrolase, family IA, variant 3
LHDAJDNO_00740 1.7e-201 P NMT1/THI5 like
LHDAJDNO_00741 1.7e-137 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
LHDAJDNO_00742 3.7e-144
LHDAJDNO_00743 1.1e-126 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
LHDAJDNO_00744 4e-262 EGP Major facilitator Superfamily
LHDAJDNO_00745 6.8e-98 S GtrA-like protein
LHDAJDNO_00746 1.3e-62 S Macrophage migration inhibitory factor (MIF)
LHDAJDNO_00747 1.3e-287 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
LHDAJDNO_00748 0.0
LHDAJDNO_00749 3.9e-145 QT PucR C-terminal helix-turn-helix domain
LHDAJDNO_00750 2.3e-130 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
LHDAJDNO_00751 3e-41 K Transcriptional regulator
LHDAJDNO_00752 0.0 fadD 6.2.1.3 I AMP-binding enzyme
LHDAJDNO_00754 1.6e-32
LHDAJDNO_00759 1.6e-07 L DNA integration
LHDAJDNO_00760 1.6e-37 L Phage integrase family
LHDAJDNO_00762 6.7e-35 D FtsK/SpoIIIE family
LHDAJDNO_00764 3.4e-52 S Eco47II restriction endonuclease
LHDAJDNO_00765 8.6e-163 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
LHDAJDNO_00766 4e-22 tam 2.1.1.144, 2.1.1.197 S Methyltransferase domain
LHDAJDNO_00767 1e-98 tam 2.1.1.144, 2.1.1.197 S Methyltransferase domain
LHDAJDNO_00768 1.6e-235 K Helix-turn-helix XRE-family like proteins
LHDAJDNO_00769 3.7e-54 relB L RelB antitoxin
LHDAJDNO_00770 1.3e-08 T Toxic component of a toxin-antitoxin (TA) module
LHDAJDNO_00771 2e-132 K helix_turn_helix, mercury resistance
LHDAJDNO_00772 1e-243 yxiO S Vacuole effluxer Atg22 like
LHDAJDNO_00774 6.5e-201 yegV G pfkB family carbohydrate kinase
LHDAJDNO_00775 1.4e-29 rpmB J Ribosomal L28 family
LHDAJDNO_00776 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
LHDAJDNO_00777 3.8e-219 steT E amino acid
LHDAJDNO_00781 1.7e-11 S Psort location CytoplasmicMembrane, score 9.99
LHDAJDNO_00782 2.9e-201 S AAA domain, putative AbiEii toxin, Type IV TA system
LHDAJDNO_00783 2.3e-96 S RloB-like protein
LHDAJDNO_00784 4.7e-220 vex3 V ABC transporter permease
LHDAJDNO_00785 9.5e-212 vex1 V Efflux ABC transporter, permease protein
LHDAJDNO_00786 9.9e-112 vex2 V ABC transporter, ATP-binding protein
LHDAJDNO_00787 8.2e-38 azlD E Branched-chain amino acid transport protein (AzlD)
LHDAJDNO_00788 3.7e-196 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
LHDAJDNO_00789 4e-95 ptpA 3.1.3.48 T low molecular weight
LHDAJDNO_00790 4.6e-128 folA 1.5.1.3 H dihydrofolate reductase
LHDAJDNO_00791 1.9e-174 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LHDAJDNO_00792 1e-72 attW O OsmC-like protein
LHDAJDNO_00793 1.6e-191 T Universal stress protein family
LHDAJDNO_00794 1.7e-108 M NlpC/P60 family
LHDAJDNO_00795 3.5e-183 usp 3.5.1.28 CBM50 S CHAP domain
LHDAJDNO_00796 1.8e-215 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LHDAJDNO_00797 2.6e-39
LHDAJDNO_00798 2.8e-219 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
LHDAJDNO_00799 1.3e-117 phoU P Plays a role in the regulation of phosphate uptake
LHDAJDNO_00800 1.8e-09 EGP Major facilitator Superfamily
LHDAJDNO_00801 4.9e-139 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LHDAJDNO_00802 1.8e-173 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
LHDAJDNO_00803 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
LHDAJDNO_00805 2.9e-218 araJ EGP Major facilitator Superfamily
LHDAJDNO_00806 0.0 S Domain of unknown function (DUF4037)
LHDAJDNO_00807 1.5e-112 S Protein of unknown function (DUF4125)
LHDAJDNO_00808 7.3e-135
LHDAJDNO_00809 2.1e-289 pspC KT PspC domain
LHDAJDNO_00810 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
LHDAJDNO_00811 5.2e-262 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LHDAJDNO_00812 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
LHDAJDNO_00813 1.4e-39 M Spy0128-like isopeptide containing domain
LHDAJDNO_00814 2.5e-29 M Spy0128-like isopeptide containing domain
LHDAJDNO_00815 0.0 crr G pts system, glucose-specific IIABC component
LHDAJDNO_00816 7.6e-152 arbG K CAT RNA binding domain
LHDAJDNO_00817 5.1e-212 I Diacylglycerol kinase catalytic domain
LHDAJDNO_00818 0.0 nucH 3.1.3.5 F 5'-nucleotidase, C-terminal domain
LHDAJDNO_00819 5.6e-229 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LHDAJDNO_00821 0.0 nagLU 3.1.4.53, 3.2.1.21, 3.2.1.50 GH3 G Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
LHDAJDNO_00822 2.9e-235 K Cell envelope-related transcriptional attenuator domain
LHDAJDNO_00823 0.0 D FtsK/SpoIIIE family
LHDAJDNO_00824 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
LHDAJDNO_00825 1.1e-284 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
LHDAJDNO_00826 2e-142 yplQ S Haemolysin-III related
LHDAJDNO_00827 2.3e-107
LHDAJDNO_00830 7.5e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LHDAJDNO_00831 5.7e-73 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
LHDAJDNO_00832 2.3e-281 sdaA 4.3.1.17 E Serine dehydratase alpha chain
LHDAJDNO_00833 1.6e-97
LHDAJDNO_00835 3.6e-185 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
LHDAJDNO_00836 2e-106 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
LHDAJDNO_00837 4.2e-101 divIC D Septum formation initiator
LHDAJDNO_00838 6.9e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LHDAJDNO_00839 1.4e-152 pabC 2.6.1.42, 2.6.1.85, 4.1.3.38 E branched-chain-amino-acid transaminase activity
LHDAJDNO_00840 2.9e-295 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH chorismate binding enzyme
LHDAJDNO_00841 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LHDAJDNO_00842 7.6e-114 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LHDAJDNO_00843 1.7e-96 2.3.1.183 M Acetyltransferase (GNAT) domain
LHDAJDNO_00844 4.9e-145 tagH 3.6.3.38, 3.6.3.40 GM ABC transporter
LHDAJDNO_00845 2.3e-150 GM ABC-2 type transporter
LHDAJDNO_00846 5.6e-197 GM GDP-mannose 4,6 dehydratase
LHDAJDNO_00847 2.6e-129 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
LHDAJDNO_00849 3.5e-191 I transferase activity, transferring acyl groups other than amino-acyl groups
LHDAJDNO_00850 6.8e-161 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
LHDAJDNO_00851 1.6e-210 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
LHDAJDNO_00852 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LHDAJDNO_00853 0.0 S Tetratricopeptide repeat
LHDAJDNO_00854 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LHDAJDNO_00855 8.2e-72 2.8.2.22 S Arylsulfotransferase Ig-like domain
LHDAJDNO_00856 3.4e-138 bioM P ATPases associated with a variety of cellular activities
LHDAJDNO_00857 2e-213 E Aminotransferase class I and II
LHDAJDNO_00858 1.7e-139 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
LHDAJDNO_00859 1.5e-104 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LHDAJDNO_00860 0.0 ecfA GP ABC transporter, ATP-binding protein
LHDAJDNO_00861 3.4e-256 EGP Major facilitator Superfamily
LHDAJDNO_00863 8.5e-257 rarA L Recombination factor protein RarA
LHDAJDNO_00864 0.0 L DEAD DEAH box helicase
LHDAJDNO_00865 2.3e-193 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
LHDAJDNO_00866 4.8e-199 gluD E Binding-protein-dependent transport system inner membrane component
LHDAJDNO_00867 1.8e-111 gluC E Binding-protein-dependent transport system inner membrane component
LHDAJDNO_00868 6e-140 gluB ET Belongs to the bacterial solute-binding protein 3 family
LHDAJDNO_00869 5.5e-49 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
LHDAJDNO_00870 1.8e-96 askB 1.1.1.3, 2.7.2.4 E ACT domain
LHDAJDNO_00871 1.4e-211 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LHDAJDNO_00872 1.7e-116
LHDAJDNO_00873 1.2e-272 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
LHDAJDNO_00874 1.3e-19 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
LHDAJDNO_00875 7.9e-279 S Calcineurin-like phosphoesterase
LHDAJDNO_00876 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LHDAJDNO_00877 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
LHDAJDNO_00878 5.4e-233 glf 5.4.99.9 M UDP-galactopyranose mutase
LHDAJDNO_00879 6.1e-123 yplQ S Haemolysin-III related
LHDAJDNO_00880 0.0 vpr M PA domain
LHDAJDNO_00881 1.5e-187 3.6.1.27 I PAP2 superfamily
LHDAJDNO_00882 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LHDAJDNO_00883 1.3e-118 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LHDAJDNO_00884 7.7e-211 holB 2.7.7.7 L DNA polymerase III
LHDAJDNO_00885 4.4e-200 K helix_turn _helix lactose operon repressor
LHDAJDNO_00886 5e-38 ptsH G PTS HPr component phosphorylation site
LHDAJDNO_00887 5.3e-290 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LHDAJDNO_00888 9.9e-93 S Fic/DOC family
LHDAJDNO_00889 7.6e-202 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
LHDAJDNO_00890 5.9e-22 G MFS/sugar transport protein
LHDAJDNO_00891 4.6e-308 efeU_1 P Iron permease FTR1 family
LHDAJDNO_00892 6.4e-109 tpd P Fe2+ transport protein
LHDAJDNO_00893 3.2e-234 S Predicted membrane protein (DUF2318)
LHDAJDNO_00894 9.7e-223 macB_2 V ABC transporter permease
LHDAJDNO_00895 4.5e-204 Z012_06715 V FtsX-like permease family
LHDAJDNO_00896 5.7e-149 macB V ABC transporter, ATP-binding protein
LHDAJDNO_00897 2.9e-70 S FMN_bind
LHDAJDNO_00898 3.6e-131 yydK K UTRA
LHDAJDNO_00899 3.6e-67 S haloacid dehalogenase-like hydrolase
LHDAJDNO_00900 7.3e-250 gmuC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LHDAJDNO_00901 4.3e-49 celA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
LHDAJDNO_00902 7.5e-39 celC 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
LHDAJDNO_00903 4e-294 bglA 3.2.1.86 GT1 G Glycosyl hydrolase family 1
LHDAJDNO_00904 3.3e-31 Q phosphatase activity
LHDAJDNO_00905 7e-81
LHDAJDNO_00906 3.5e-241 S Putative ABC-transporter type IV
LHDAJDNO_00907 1.1e-161 S Sucrose-6F-phosphate phosphohydrolase
LHDAJDNO_00909 3e-73 E IrrE N-terminal-like domain
LHDAJDNO_00910 6.5e-81 K Winged helix DNA-binding domain
LHDAJDNO_00911 7e-301 V ABC transporter, ATP-binding protein
LHDAJDNO_00912 0.0 V ABC transporter transmembrane region
LHDAJDNO_00913 1.6e-84
LHDAJDNO_00914 1.9e-52 XK26_04485 P Cobalt transport protein
LHDAJDNO_00916 9.2e-305 pepD E Peptidase family C69
LHDAJDNO_00917 0.0 S Glycosyl hydrolases related to GH101 family, GH129
LHDAJDNO_00918 1.5e-197 XK27_01805 M Glycosyltransferase like family 2
LHDAJDNO_00919 1.2e-116 icaR K Bacterial regulatory proteins, tetR family
LHDAJDNO_00921 2.4e-194 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LHDAJDNO_00922 1.3e-219 amt U Ammonium Transporter Family
LHDAJDNO_00923 1e-54 glnB K Nitrogen regulatory protein P-II
LHDAJDNO_00924 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
LHDAJDNO_00925 1.1e-18 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
LHDAJDNO_00926 7e-251 dinF V MatE
LHDAJDNO_00927 7.5e-258 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
LHDAJDNO_00928 1.7e-282 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
LHDAJDNO_00929 7.5e-143 cobQ S CobB/CobQ-like glutamine amidotransferase domain
LHDAJDNO_00930 3.5e-19 S granule-associated protein
LHDAJDNO_00931 0.0 ubiB S ABC1 family
LHDAJDNO_00932 0.0 pacS 3.6.3.54 P E1-E2 ATPase
LHDAJDNO_00933 9.6e-43 csoR S Metal-sensitive transcriptional repressor
LHDAJDNO_00934 1.3e-214 rmuC S RmuC family
LHDAJDNO_00935 5.9e-129 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LHDAJDNO_00936 6.9e-156 spoU 2.1.1.185 J RNA methyltransferase TrmH family
LHDAJDNO_00937 9.6e-59 V ABC transporter
LHDAJDNO_00938 1e-60 V ABC transporter
LHDAJDNO_00939 6.2e-48 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LHDAJDNO_00940 6.4e-290 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LHDAJDNO_00941 1.4e-286 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LHDAJDNO_00942 1.7e-198 2.3.1.57 J Acetyltransferase (GNAT) domain
LHDAJDNO_00943 3.3e-52 S Protein of unknown function (DUF2469)
LHDAJDNO_00944 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
LHDAJDNO_00945 3.6e-304 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LHDAJDNO_00946 7.2e-236 E Aminotransferase class I and II
LHDAJDNO_00947 3.1e-90 lrp_3 K helix_turn_helix ASNC type
LHDAJDNO_00948 4.7e-73 tyrA 5.4.99.5 E Chorismate mutase type II
LHDAJDNO_00949 0.0 S domain protein
LHDAJDNO_00950 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LHDAJDNO_00951 4.3e-294 E Bacterial extracellular solute-binding proteins, family 5 Middle
LHDAJDNO_00952 1.5e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LHDAJDNO_00953 4.8e-134 KT Transcriptional regulatory protein, C terminal
LHDAJDNO_00954 1.4e-125
LHDAJDNO_00956 2.7e-100 mntP P Probably functions as a manganese efflux pump
LHDAJDNO_00958 5.2e-92 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LHDAJDNO_00959 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
LHDAJDNO_00960 0.0 K RNA polymerase II activating transcription factor binding
LHDAJDNO_00961 4.6e-35
LHDAJDNO_00963 2e-207 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LHDAJDNO_00964 6e-146 atpB C it plays a direct role in the translocation of protons across the membrane
LHDAJDNO_00966 1.2e-30 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LHDAJDNO_00967 4.6e-62 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LHDAJDNO_00968 7e-150 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LHDAJDNO_00969 0.0 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LHDAJDNO_00970 2.7e-166 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LHDAJDNO_00971 1.5e-283 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LHDAJDNO_00972 8.7e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
LHDAJDNO_00973 0.0 S LPXTG-motif cell wall anchor domain protein
LHDAJDNO_00974 1.4e-242 M LPXTG-motif cell wall anchor domain protein
LHDAJDNO_00975 4.5e-180 3.4.22.70 M Sortase family
LHDAJDNO_00976 2.4e-153
LHDAJDNO_00977 3e-270 KLT Domain of unknown function (DUF4032)
LHDAJDNO_00978 9.9e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LHDAJDNO_00980 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
LHDAJDNO_00981 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
LHDAJDNO_00982 5.3e-112 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
LHDAJDNO_00983 0.0 yjcE P Sodium/hydrogen exchanger family
LHDAJDNO_00984 1.2e-145 ypfH S Phospholipase/Carboxylesterase
LHDAJDNO_00985 1.1e-83 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LHDAJDNO_00986 1.3e-234 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
LHDAJDNO_00987 3e-144 cobB2 K Sir2 family
LHDAJDNO_00988 1.9e-16 K Putative DNA-binding domain
LHDAJDNO_00989 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
LHDAJDNO_00990 6.8e-281 argH 4.3.2.1 E argininosuccinate lyase
LHDAJDNO_00991 7.2e-109 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
LHDAJDNO_00992 4.6e-143 S Putative ABC-transporter type IV
LHDAJDNO_00993 2.4e-253 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LHDAJDNO_00994 3.2e-159 L Tetratricopeptide repeat
LHDAJDNO_00995 3.7e-193 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
LHDAJDNO_00997 3.6e-137 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
LHDAJDNO_00998 3.6e-104
LHDAJDNO_00999 6.8e-116 trkA P TrkA-N domain
LHDAJDNO_01000 3.9e-236 trkB P Cation transport protein
LHDAJDNO_01001 2.1e-182 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LHDAJDNO_01002 2.9e-294 recN L May be involved in recombinational repair of damaged DNA
LHDAJDNO_01003 5.8e-123 S Haloacid dehalogenase-like hydrolase
LHDAJDNO_01004 3.7e-58 K helix_turn_helix gluconate operon transcriptional repressor
LHDAJDNO_01005 2e-177 V ATPases associated with a variety of cellular activities
LHDAJDNO_01006 2.4e-125 S ABC-2 family transporter protein
LHDAJDNO_01007 9.6e-124 S ABC-2 family transporter protein
LHDAJDNO_01008 4.6e-285 thrC 4.2.3.1 E Threonine synthase N terminus
LHDAJDNO_01009 5.3e-237 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LHDAJDNO_01011 4.2e-135 L Phage integrase family
LHDAJDNO_01012 2.9e-108 3.4.13.21 E Peptidase family S51
LHDAJDNO_01013 6.3e-274 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
LHDAJDNO_01014 9.8e-233 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LHDAJDNO_01015 0.0 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
LHDAJDNO_01016 1e-281 XK27_07020 S Domain of unknown function (DUF1846)
LHDAJDNO_01017 1.7e-122
LHDAJDNO_01019 9.9e-112 ysdA S Protein of unknown function (DUF1294)
LHDAJDNO_01020 1.2e-27
LHDAJDNO_01021 4.4e-11
LHDAJDNO_01023 1.1e-302 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
LHDAJDNO_01024 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
LHDAJDNO_01025 3.4e-189 pit P Phosphate transporter family
LHDAJDNO_01026 1.1e-115 MA20_27875 P Protein of unknown function DUF47
LHDAJDNO_01027 1.2e-118 K helix_turn_helix, Lux Regulon
LHDAJDNO_01028 9.2e-234 T Histidine kinase
LHDAJDNO_01029 1.2e-42 pacL 3.6.3.8, 3.6.3.9 P ATPase, P-type transporting, HAD superfamily, subfamily IC
LHDAJDNO_01030 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
LHDAJDNO_01031 5.9e-100 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LHDAJDNO_01032 1.3e-162 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
LHDAJDNO_01034 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
LHDAJDNO_01035 4e-119
LHDAJDNO_01036 3e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LHDAJDNO_01037 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
LHDAJDNO_01038 9.5e-116 xylR K purine nucleotide biosynthetic process
LHDAJDNO_01039 1.2e-92 lemA S LemA family
LHDAJDNO_01040 0.0 S Predicted membrane protein (DUF2207)
LHDAJDNO_01041 1.9e-75 megL 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
LHDAJDNO_01042 1.6e-189 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LHDAJDNO_01043 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LHDAJDNO_01044 1.5e-73 nrdI F Probably involved in ribonucleotide reductase function
LHDAJDNO_01045 0.0 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
LHDAJDNO_01046 2.1e-207 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
LHDAJDNO_01047 0.0 S Uncharacterised protein family (UPF0182)
LHDAJDNO_01048 7.4e-231 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
LHDAJDNO_01049 2.2e-196
LHDAJDNO_01050 4.3e-152 ytrE V ATPases associated with a variety of cellular activities
LHDAJDNO_01051 7e-190 V N-Acetylmuramoyl-L-alanine amidase
LHDAJDNO_01052 3.4e-258 argE E Peptidase dimerisation domain
LHDAJDNO_01053 1.2e-103 S Protein of unknown function (DUF3043)
LHDAJDNO_01054 1.1e-278 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LHDAJDNO_01055 5.3e-139 S Domain of unknown function (DUF4191)
LHDAJDNO_01056 1.8e-286 glnA 6.3.1.2 E glutamine synthetase
LHDAJDNO_01057 4.3e-18
LHDAJDNO_01059 4.2e-19
LHDAJDNO_01063 2.7e-94 L Transposase and inactivated derivatives IS30 family
LHDAJDNO_01064 1.1e-256 S Domain of unknown function (DUF4143)
LHDAJDNO_01065 2.3e-57 yccF S Inner membrane component domain
LHDAJDNO_01066 4.5e-12
LHDAJDNO_01067 0.0 cysB 4.2.1.22 EGP Major facilitator Superfamily
LHDAJDNO_01068 1.1e-42 tnp7109-21 L Integrase core domain
LHDAJDNO_01069 4.7e-84 V ATPases associated with a variety of cellular activities
LHDAJDNO_01070 2e-73 I Sterol carrier protein
LHDAJDNO_01071 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
LHDAJDNO_01072 3.4e-35
LHDAJDNO_01073 1.4e-144 gluP 3.4.21.105 S Rhomboid family
LHDAJDNO_01074 1.2e-255 L ribosomal rna small subunit methyltransferase
LHDAJDNO_01075 2.6e-71 crgA D Involved in cell division
LHDAJDNO_01076 7.9e-143 S Bacterial protein of unknown function (DUF881)
LHDAJDNO_01077 1.7e-232 srtA 3.4.22.70 M Sortase family
LHDAJDNO_01078 3.4e-120 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
LHDAJDNO_01079 4.2e-142 pknB 2.7.11.1 KLT Protein tyrosine kinase
LHDAJDNO_01080 1.5e-277 oatA I Psort location CytoplasmicMembrane, score 9.99
LHDAJDNO_01081 1e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LHDAJDNO_01082 1.3e-127 lolD V ABC transporter
LHDAJDNO_01083 8.5e-213 V FtsX-like permease family
LHDAJDNO_01084 8.2e-64 S Domain of unknown function (DUF4418)
LHDAJDNO_01085 0.0 pcrA 3.6.4.12 L DNA helicase
LHDAJDNO_01086 0.0 yrhL I Psort location CytoplasmicMembrane, score 9.99
LHDAJDNO_01087 3e-107 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LHDAJDNO_01088 2.8e-241 pbuX F Permease family
LHDAJDNO_01090 1.4e-46 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LHDAJDNO_01092 5.6e-112 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
LHDAJDNO_01093 2e-39
LHDAJDNO_01094 1.1e-26 2.1.1.72 S Adenine-specific methyltransferase EcoRI
LHDAJDNO_01095 5.4e-175 tnp7109-21 L Integrase core domain
LHDAJDNO_01096 2.8e-46 L Transposase
LHDAJDNO_01097 3.5e-64 D MobA/MobL family
LHDAJDNO_01098 9.8e-85
LHDAJDNO_01100 3.2e-80 L Transposase and inactivated derivatives IS30 family
LHDAJDNO_01101 1.8e-113 pknL 2.7.11.1 KLT PASTA
LHDAJDNO_01102 1.7e-50 pknL 2.7.11.1 KLT PASTA
LHDAJDNO_01103 1.4e-201 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
LHDAJDNO_01104 8.5e-122
LHDAJDNO_01105 5.3e-180 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LHDAJDNO_01106 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
LHDAJDNO_01107 5.2e-278 aspA 4.3.1.1 E Fumarase C C-terminus
LHDAJDNO_01108 1.2e-36 K Transcriptional regulator
LHDAJDNO_01109 0.0 lhr L DEAD DEAH box helicase
LHDAJDNO_01110 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
LHDAJDNO_01111 9.5e-236 S Type I phosphodiesterase / nucleotide pyrophosphatase
LHDAJDNO_01112 1.1e-45
LHDAJDNO_01113 2.3e-142 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
LHDAJDNO_01114 1.6e-69 S Protein of unknown function (DUF4235)
LHDAJDNO_01115 7.9e-131 G Phosphoglycerate mutase family
LHDAJDNO_01117 2.9e-190 K Psort location Cytoplasmic, score
LHDAJDNO_01118 0.0 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
LHDAJDNO_01119 0.0 dnaK O Heat shock 70 kDa protein
LHDAJDNO_01120 2.8e-59 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LHDAJDNO_01121 2.4e-173 dnaJ1 O DnaJ molecular chaperone homology domain
LHDAJDNO_01122 6.8e-87 hspR K transcriptional regulator, MerR family
LHDAJDNO_01123 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR repeat-like domain
LHDAJDNO_01124 3.2e-138 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR repeat-like domain
LHDAJDNO_01125 5.4e-264 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR Asp-box repeat
LHDAJDNO_01126 2.1e-29 pepD E Peptidase family C69
LHDAJDNO_01127 2.2e-265 pepD E Peptidase family C69
LHDAJDNO_01128 3.7e-107 S Phosphatidylethanolamine-binding protein
LHDAJDNO_01129 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
LHDAJDNO_01130 0.0 lmrA2 V ABC transporter transmembrane region
LHDAJDNO_01131 1.2e-244 lmrA1 V ABC transporter, ATP-binding protein
LHDAJDNO_01132 3.4e-77 lmrA1 V ABC transporter, ATP-binding protein
LHDAJDNO_01133 5.9e-94 ydgJ K helix_turn_helix multiple antibiotic resistance protein
LHDAJDNO_01134 3.3e-191 1.1.1.65 C Aldo/keto reductase family
LHDAJDNO_01136 1.8e-53 M Belongs to the glycosyl hydrolase 30 family
LHDAJDNO_01137 7.2e-136 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LHDAJDNO_01138 1.3e-90 mraZ K Belongs to the MraZ family
LHDAJDNO_01139 0.0 L DNA helicase
LHDAJDNO_01140 1.7e-229 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
LHDAJDNO_01141 2.3e-83 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LHDAJDNO_01142 1.7e-50 M Lysin motif
LHDAJDNO_01143 7.5e-129 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LHDAJDNO_01144 6e-166 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LHDAJDNO_01145 4.6e-177 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
LHDAJDNO_01146 2e-272 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LHDAJDNO_01147 3.9e-173
LHDAJDNO_01148 3.1e-121 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
LHDAJDNO_01149 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
LHDAJDNO_01150 1.2e-154 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
LHDAJDNO_01151 2.1e-61 EGP Major facilitator Superfamily
LHDAJDNO_01152 1e-251 S Domain of unknown function (DUF5067)
LHDAJDNO_01153 2.1e-265 glnA2 6.3.1.2 E glutamine synthetase
LHDAJDNO_01154 4.9e-284 S Uncharacterized protein conserved in bacteria (DUF2252)
LHDAJDNO_01155 4.9e-131 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
LHDAJDNO_01156 1.4e-121 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LHDAJDNO_01157 1.7e-112
LHDAJDNO_01158 3.2e-112 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
LHDAJDNO_01159 2.1e-224 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LHDAJDNO_01160 2.1e-255 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LHDAJDNO_01161 2.3e-181 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
LHDAJDNO_01163 1.2e-76 yneG S Domain of unknown function (DUF4186)
LHDAJDNO_01164 6.4e-173 dkgA 1.1.1.346 C Aldo/keto reductase family
LHDAJDNO_01165 5e-156 yvgN 1.1.1.346 S Aldo/keto reductase family
LHDAJDNO_01166 3.4e-202 K WYL domain
LHDAJDNO_01168 0.0 4.2.1.53 S MCRA family
LHDAJDNO_01169 2e-46 yhbY J CRS1_YhbY
LHDAJDNO_01170 7.6e-106 S zinc-ribbon domain
LHDAJDNO_01171 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
LHDAJDNO_01172 8.8e-39 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
LHDAJDNO_01173 1.7e-15 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
LHDAJDNO_01174 5.1e-192 ywqG S Domain of unknown function (DUF1963)
LHDAJDNO_01175 1.5e-154 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LHDAJDNO_01176 2.3e-142 recO L Involved in DNA repair and RecF pathway recombination
LHDAJDNO_01177 1.9e-292 I acetylesterase activity
LHDAJDNO_01178 3.9e-235 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LHDAJDNO_01179 3.7e-221 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
LHDAJDNO_01180 1.3e-202 2.7.11.1 NU Tfp pilus assembly protein FimV
LHDAJDNO_01182 3.3e-23
LHDAJDNO_01183 5.7e-19
LHDAJDNO_01184 4.9e-150 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
LHDAJDNO_01185 3e-76 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
LHDAJDNO_01186 1.4e-164 usp 3.5.1.28 CBM50 D CHAP domain protein
LHDAJDNO_01187 1e-157 ftsX D Part of the ABC transporter FtsEX involved in cellular division
LHDAJDNO_01188 5.9e-197 ftsE D Cell division ATP-binding protein FtsE
LHDAJDNO_01189 8.2e-202 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LHDAJDNO_01190 1.5e-146 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
LHDAJDNO_01191 6e-63
LHDAJDNO_01193 2e-177 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
LHDAJDNO_01194 9.9e-102 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LHDAJDNO_01195 9.7e-90 3.1.21.3 V DivIVA protein
LHDAJDNO_01196 2.1e-42 yggT S YGGT family
LHDAJDNO_01197 4.3e-80 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LHDAJDNO_01198 7.3e-231 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LHDAJDNO_01199 3.6e-246 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LHDAJDNO_01200 2.3e-300 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
LHDAJDNO_01201 0.0 lacZ 3.2.1.23 G Domain of unknown function (DUF4982)
LHDAJDNO_01202 6.1e-160 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LHDAJDNO_01203 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LHDAJDNO_01204 1.3e-84
LHDAJDNO_01205 6.9e-231 O AAA domain (Cdc48 subfamily)
LHDAJDNO_01206 2.7e-163 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
LHDAJDNO_01207 8e-61 S Thiamine-binding protein
LHDAJDNO_01208 1.2e-196 K helix_turn _helix lactose operon repressor
LHDAJDNO_01209 5.7e-47 S Protein of unknown function (DUF3052)
LHDAJDNO_01210 7.6e-152 lon T Belongs to the peptidase S16 family
LHDAJDNO_01211 1.8e-284 S Zincin-like metallopeptidase
LHDAJDNO_01212 1.5e-280 uvrD2 3.6.4.12 L DNA helicase
LHDAJDNO_01213 8.7e-244 mphA S Aminoglycoside phosphotransferase
LHDAJDNO_01214 6.1e-32 S Protein of unknown function (DUF3107)
LHDAJDNO_01215 1.9e-166 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
LHDAJDNO_01216 7.6e-115 S Vitamin K epoxide reductase
LHDAJDNO_01217 5.6e-169 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
LHDAJDNO_01218 4.6e-154 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
LHDAJDNO_01219 1.2e-169 S Patatin-like phospholipase
LHDAJDNO_01220 0.0 V ABC transporter transmembrane region
LHDAJDNO_01221 0.0 V ABC transporter, ATP-binding protein
LHDAJDNO_01222 1.1e-90 K MarR family
LHDAJDNO_01224 0.0 plyA3 3.2.1.18 GH33 M Parallel beta-helix repeats
LHDAJDNO_01225 3.4e-261 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
LHDAJDNO_01226 1.9e-164
LHDAJDNO_01227 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
LHDAJDNO_01229 2.5e-140 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LHDAJDNO_01230 1.4e-91 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
LHDAJDNO_01231 0.0 pip S YhgE Pip domain protein
LHDAJDNO_01232 0.0 pip S YhgE Pip domain protein
LHDAJDNO_01233 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
LHDAJDNO_01234 5.2e-130 fhaA T Protein of unknown function (DUF2662)
LHDAJDNO_01235 7.9e-94 fhaB T Inner membrane component of T3SS, cytoplasmic domain
LHDAJDNO_01236 4.8e-259 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
LHDAJDNO_01237 2.8e-266 rodA D Belongs to the SEDS family
LHDAJDNO_01238 2.3e-260 pbpA M penicillin-binding protein
LHDAJDNO_01239 2e-183 T Protein tyrosine kinase
LHDAJDNO_01240 3.6e-53 acyP 3.6.1.7 C Acylphosphatase
LHDAJDNO_01241 1.2e-146 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LHDAJDNO_01242 5.4e-186 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
LHDAJDNO_01243 3.9e-129 M Protein of unknown function (DUF3152)
LHDAJDNO_01244 3.7e-131 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
LHDAJDNO_01246 1.2e-65 E Domain of unknown function (DUF5011)
LHDAJDNO_01247 2e-35 S Parallel beta-helix repeats
LHDAJDNO_01248 6.6e-70 rplI J Binds to the 23S rRNA
LHDAJDNO_01249 2e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LHDAJDNO_01250 1.9e-78 ssb1 L Single-stranded DNA-binding protein
LHDAJDNO_01251 6.1e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
LHDAJDNO_01252 6.7e-176 T Pfam Adenylate and Guanylate cyclase catalytic domain
LHDAJDNO_01253 1.6e-118
LHDAJDNO_01254 2.2e-19 ftsK 2.7.11.1, 2.7.7.7, 3.4.21.110, 4.2.1.2 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LHDAJDNO_01255 1.3e-17 ftsK 2.7.11.1, 2.7.7.7, 3.4.21.110, 4.2.1.2 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LHDAJDNO_01256 0.0 macB_2 V ATPases associated with a variety of cellular activities
LHDAJDNO_01257 0.0 ctpE P E1-E2 ATPase
LHDAJDNO_01258 4.1e-197 yghZ C Aldo/keto reductase family
LHDAJDNO_01259 1.1e-100 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
LHDAJDNO_01260 1.1e-250 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
LHDAJDNO_01261 1.1e-149 map 3.4.11.18 E Methionine aminopeptidase
LHDAJDNO_01262 3.1e-127 S Short repeat of unknown function (DUF308)
LHDAJDNO_01263 0.0 pepO 3.4.24.71 O Peptidase family M13
LHDAJDNO_01264 7.9e-54 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
LHDAJDNO_01266 6.2e-151 IQ KR domain
LHDAJDNO_01267 1e-63 4.2.1.68 M Enolase C-terminal domain-like
LHDAJDNO_01268 1.6e-17 4.2.1.68 M carboxylic acid catabolic process
LHDAJDNO_01269 1.4e-184 K Bacterial regulatory proteins, lacI family
LHDAJDNO_01271 2.8e-119 cyaA 4.6.1.1 S CYTH
LHDAJDNO_01272 1.1e-162 trxA2 O Tetratricopeptide repeat
LHDAJDNO_01273 7.9e-180
LHDAJDNO_01274 5.4e-187
LHDAJDNO_01275 1.4e-165 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
LHDAJDNO_01276 6.1e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LHDAJDNO_01277 2.3e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LHDAJDNO_01278 4.7e-126
LHDAJDNO_01279 7.3e-132 K Bacterial regulatory proteins, tetR family
LHDAJDNO_01280 5.6e-34 S Domain of unknown function (DUF4854)
LHDAJDNO_01281 4.2e-155 fahA Q Fumarylacetoacetate (FAA) hydrolase family
LHDAJDNO_01282 9.6e-30 2.1.1.72 S Protein conserved in bacteria
LHDAJDNO_01283 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
LHDAJDNO_01284 2.7e-132 M Mechanosensitive ion channel
LHDAJDNO_01285 1.7e-119 K Bacterial regulatory proteins, tetR family
LHDAJDNO_01286 4.2e-239 MA20_36090 S Psort location Cytoplasmic, score 8.87
LHDAJDNO_01287 1.2e-232 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
LHDAJDNO_01288 5.6e-65
LHDAJDNO_01290 2.1e-37 L Psort location Cytoplasmic, score 8.87
LHDAJDNO_01291 8.6e-120 E Psort location Cytoplasmic, score 8.87
LHDAJDNO_01292 5.6e-59 yccF S Inner membrane component domain
LHDAJDNO_01293 2.3e-156 ksgA 2.1.1.182 J Methyltransferase domain
LHDAJDNO_01294 7.9e-66 S Cupin 2, conserved barrel domain protein
LHDAJDNO_01295 3.7e-259 KLT Protein tyrosine kinase
LHDAJDNO_01296 2.6e-79 K Psort location Cytoplasmic, score
LHDAJDNO_01297 1.1e-149
LHDAJDNO_01298 2.7e-22
LHDAJDNO_01299 5.4e-197 S Short C-terminal domain
LHDAJDNO_01300 2.7e-87 S Helix-turn-helix
LHDAJDNO_01301 5.2e-65 S Zincin-like metallopeptidase
LHDAJDNO_01302 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LHDAJDNO_01303 4.7e-84 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LHDAJDNO_01304 1.6e-238 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LHDAJDNO_01305 6.5e-232 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
LHDAJDNO_01306 2.5e-253 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LHDAJDNO_01307 1e-105
LHDAJDNO_01309 5.4e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LHDAJDNO_01310 7.8e-202 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LHDAJDNO_01311 2.2e-105 L transposase activity
LHDAJDNO_01312 5.3e-105 L PFAM Integrase catalytic
LHDAJDNO_01313 2.5e-155 L Transposase, Mutator family
LHDAJDNO_01314 1.2e-168 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LHDAJDNO_01315 8.7e-131 rgpC U Transport permease protein
LHDAJDNO_01316 1.3e-208 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
LHDAJDNO_01317 2.5e-294 S Tetratricopeptide repeat
LHDAJDNO_01318 0.0 rgpF M Rhamnan synthesis protein F
LHDAJDNO_01319 2.2e-193 M Glycosyltransferase like family 2
LHDAJDNO_01320 4.4e-109
LHDAJDNO_01321 4e-192 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
LHDAJDNO_01322 1.3e-218 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
LHDAJDNO_01323 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
LHDAJDNO_01324 2.3e-92 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LHDAJDNO_01325 3.6e-31 J Acetyltransferase (GNAT) domain
LHDAJDNO_01326 7.1e-94 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LHDAJDNO_01327 1.5e-269 yhdG E aromatic amino acid transport protein AroP K03293
LHDAJDNO_01328 3.2e-245 tcsS3 KT PspC domain
LHDAJDNO_01329 9.2e-126 degU K helix_turn_helix, Lux Regulon
LHDAJDNO_01330 5.3e-278 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LHDAJDNO_01332 2.3e-142 pgl 3.1.1.31 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
LHDAJDNO_01333 4.2e-186 opcA G Glucose-6-phosphate dehydrogenase subunit
LHDAJDNO_01334 0.0 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LHDAJDNO_01335 1.5e-94
LHDAJDNO_01337 2.8e-188 nusA K Participates in both transcription termination and antitermination
LHDAJDNO_01338 5.3e-157
LHDAJDNO_01339 7.9e-45 L Transposase and inactivated derivatives
LHDAJDNO_01340 8.3e-26
LHDAJDNO_01342 5e-153 E Transglutaminase/protease-like homologues
LHDAJDNO_01343 0.0 gcs2 S A circularly permuted ATPgrasp
LHDAJDNO_01344 6.4e-173 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LHDAJDNO_01345 0.0 3.2.1.52 GH20 G hydrolase family 20, catalytic
LHDAJDNO_01346 2.8e-64 rplQ J Ribosomal protein L17
LHDAJDNO_01347 8.9e-184 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LHDAJDNO_01348 1.1e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LHDAJDNO_01349 3.3e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LHDAJDNO_01350 6.5e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
LHDAJDNO_01351 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LHDAJDNO_01352 3.8e-99 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LHDAJDNO_01353 4.7e-249 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LHDAJDNO_01354 2.7e-63 rplO J binds to the 23S rRNA
LHDAJDNO_01355 1e-24 rpmD J Ribosomal protein L30p/L7e
LHDAJDNO_01356 1.5e-100 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LHDAJDNO_01357 1.1e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LHDAJDNO_01358 2.1e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LHDAJDNO_01359 4.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LHDAJDNO_01360 9.2e-18 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LHDAJDNO_01361 2.2e-102 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LHDAJDNO_01362 3.5e-52 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LHDAJDNO_01363 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LHDAJDNO_01364 3.5e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LHDAJDNO_01365 5e-38 rpmC J Belongs to the universal ribosomal protein uL29 family
LHDAJDNO_01366 5.8e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LHDAJDNO_01367 7.5e-96 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LHDAJDNO_01368 4.3e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LHDAJDNO_01369 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LHDAJDNO_01370 4.2e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LHDAJDNO_01371 2.6e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LHDAJDNO_01372 1.9e-118 rplD J Forms part of the polypeptide exit tunnel
LHDAJDNO_01373 4.2e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LHDAJDNO_01374 5.2e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
LHDAJDNO_01375 2.6e-105 ywiC S YwiC-like protein
LHDAJDNO_01376 2.4e-27 ywiC S YwiC-like protein
LHDAJDNO_01377 1.9e-166 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
LHDAJDNO_01378 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
LHDAJDNO_01379 3.1e-231 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
LHDAJDNO_01380 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
LHDAJDNO_01381 8.8e-68 rpsI J Belongs to the universal ribosomal protein uS9 family
LHDAJDNO_01382 3.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LHDAJDNO_01383 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
LHDAJDNO_01384 3.3e-119
LHDAJDNO_01385 2e-112 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
LHDAJDNO_01386 5.3e-256 M Bacterial capsule synthesis protein PGA_cap
LHDAJDNO_01388 3.3e-239 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LHDAJDNO_01389 3.6e-224 dapC E Aminotransferase class I and II
LHDAJDNO_01390 9e-61 fdxA C 4Fe-4S binding domain
LHDAJDNO_01391 1.5e-214 murB 1.3.1.98 M Cell wall formation
LHDAJDNO_01392 1.9e-25 rpmG J Ribosomal protein L33
LHDAJDNO_01396 9.2e-52 moxR S ATPase family associated with various cellular activities (AAA)
LHDAJDNO_01397 1.1e-128 bla1 3.5.2.6 V Beta-lactamase enzyme family
LHDAJDNO_01398 1.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LHDAJDNO_01399 1.4e-147
LHDAJDNO_01400 5.8e-148 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
LHDAJDNO_01401 1.8e-121 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
LHDAJDNO_01402 3.2e-38 fmdB S Putative regulatory protein
LHDAJDNO_01403 6.2e-109 flgA NO SAF
LHDAJDNO_01404 9.6e-42
LHDAJDNO_01405 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
LHDAJDNO_01406 5.7e-244 T Forkhead associated domain
LHDAJDNO_01408 1.3e-37 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LHDAJDNO_01409 2.1e-88 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LHDAJDNO_01410 3.8e-174 xynB2 1.1.1.169 E lipolytic protein G-D-S-L family
LHDAJDNO_01411 0.0 guxA1 3.2.1.18, 3.2.1.91 GH33,GH6 G BNR repeat-like domain
LHDAJDNO_01413 1.2e-210 pbuO S Permease family
LHDAJDNO_01414 1.4e-12 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
LHDAJDNO_01415 3e-170 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
LHDAJDNO_01416 3.6e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LHDAJDNO_01417 6.2e-180 pstA P Phosphate transport system permease
LHDAJDNO_01418 3.8e-171 pstC P probably responsible for the translocation of the substrate across the membrane
LHDAJDNO_01419 1.4e-169 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
LHDAJDNO_01420 3.7e-128 KT Transcriptional regulatory protein, C terminal
LHDAJDNO_01421 4.2e-245 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
LHDAJDNO_01422 8.7e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LHDAJDNO_01423 8.3e-240 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LHDAJDNO_01424 8.2e-108 K helix_turn_helix, Arsenical Resistance Operon Repressor
LHDAJDNO_01425 2e-242 EGP Major facilitator Superfamily
LHDAJDNO_01426 1.1e-219 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LHDAJDNO_01427 3.4e-170 L Excalibur calcium-binding domain
LHDAJDNO_01428 3.2e-269 pepC 3.4.22.40 E Peptidase C1-like family
LHDAJDNO_01429 4e-47 D nuclear chromosome segregation
LHDAJDNO_01430 8e-128 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LHDAJDNO_01431 1.1e-144 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
LHDAJDNO_01432 1e-187 yfiH Q Multi-copper polyphenol oxidoreductase laccase
LHDAJDNO_01433 0.0 yegQ O Peptidase family U32 C-terminal domain
LHDAJDNO_01434 8e-16 S G5
LHDAJDNO_01436 6.4e-151 O Thioredoxin
LHDAJDNO_01437 0.0 KLT Protein tyrosine kinase
LHDAJDNO_01438 1.2e-174 K Psort location Cytoplasmic, score
LHDAJDNO_01439 3.3e-211 ugpC E Belongs to the ABC transporter superfamily
LHDAJDNO_01440 9.8e-100 L Helix-turn-helix domain
LHDAJDNO_01441 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
LHDAJDNO_01442 8e-307 pccB I Carboxyl transferase domain
LHDAJDNO_01443 1.1e-96 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
LHDAJDNO_01444 1.9e-103 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
LHDAJDNO_01445 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
LHDAJDNO_01446 3e-76 nadB 1.3.5.4, 1.4.3.16, 2.4.2.19 H Catalyzes the oxidation of L-aspartate to iminoaspartate
LHDAJDNO_01447 9.8e-252 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LHDAJDNO_01448 1.6e-148 nrtR 3.6.1.55 F NUDIX hydrolase
LHDAJDNO_01449 1.6e-112 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LHDAJDNO_01450 1.2e-149 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LHDAJDNO_01451 1.8e-152 soj D CobQ CobB MinD ParA nucleotide binding domain protein
LHDAJDNO_01452 2.9e-179 xerD D recombinase XerD
LHDAJDNO_01453 9.6e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LHDAJDNO_01454 2.1e-25 rpmI J Ribosomal protein L35
LHDAJDNO_01455 7.9e-17 M Belongs to the glycosyl hydrolase 30 family
LHDAJDNO_01457 3.8e-152 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
LHDAJDNO_01458 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
LHDAJDNO_01459 7.5e-126 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LHDAJDNO_01460 1.3e-77 S CRISPR-associated protein (Cas_Csn2)
LHDAJDNO_01461 0.0 inlJ M domain protein
LHDAJDNO_01462 1.9e-276 M LPXTG cell wall anchor motif
LHDAJDNO_01463 9.7e-214 3.4.22.70 M Sortase family
LHDAJDNO_01464 5.1e-96 K Putative ATP-dependent DNA helicase recG C-terminal
LHDAJDNO_01465 3.9e-159 K Helix-turn-helix domain, rpiR family
LHDAJDNO_01466 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LHDAJDNO_01467 2.9e-248 dgt 3.1.5.1 F Phosphohydrolase-associated domain
LHDAJDNO_01468 3e-195 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LHDAJDNO_01469 1.2e-97 S Protein of unknown function (DUF3071)
LHDAJDNO_01470 1.4e-47 S Domain of unknown function (DUF4193)
LHDAJDNO_01471 2.2e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
LHDAJDNO_01472 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LHDAJDNO_01473 9e-28
LHDAJDNO_01474 1.4e-65 L Phage integrase family
LHDAJDNO_01475 1.3e-284 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
LHDAJDNO_01476 6e-250 V ABC-2 family transporter protein
LHDAJDNO_01477 8.1e-227 V ABC-2 family transporter protein
LHDAJDNO_01478 2.7e-64 V ATPases associated with a variety of cellular activities
LHDAJDNO_01479 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LHDAJDNO_01480 1.3e-99 sixA T Phosphoglycerate mutase family
LHDAJDNO_01481 3.5e-205 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
LHDAJDNO_01482 4.8e-108 I alpha/beta hydrolase fold
LHDAJDNO_01483 3.1e-29 L Transposase
LHDAJDNO_01484 4.4e-45 L Transposase DDE domain
LHDAJDNO_01485 1e-289 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LHDAJDNO_01486 0.0 3.6.4.12 K Putative DNA-binding domain
LHDAJDNO_01487 2.5e-202 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LHDAJDNO_01488 0.0
LHDAJDNO_01489 2.4e-107 rfbJ M Glycosyl transferase family 2
LHDAJDNO_01490 2.5e-206 lytC 2.1.1.197, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
LHDAJDNO_01491 3e-86 lytC 2.1.1.197, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
LHDAJDNO_01492 1.8e-28 I transferase activity, transferring acyl groups other than amino-acyl groups
LHDAJDNO_01493 1.8e-203 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LHDAJDNO_01494 1.5e-101 T protein histidine kinase activity
LHDAJDNO_01495 2.3e-87 K LytTr DNA-binding domain
LHDAJDNO_01496 8.7e-47 S Protein of unknown function (DUF3073)
LHDAJDNO_01497 3.2e-203 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
LHDAJDNO_01498 1.8e-195 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
LHDAJDNO_01499 2.1e-55 S Amidohydrolase family
LHDAJDNO_01500 1.9e-152 S Amidohydrolase family
LHDAJDNO_01501 0.0 yjjP S Threonine/Serine exporter, ThrE
LHDAJDNO_01502 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LHDAJDNO_01503 8.1e-238 yhjX EGP Major facilitator Superfamily
LHDAJDNO_01504 6.5e-309 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
LHDAJDNO_01505 0.0 trxB1 1.8.1.9 C Thioredoxin domain
LHDAJDNO_01506 2.9e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
LHDAJDNO_01507 2e-118 cah 4.2.1.1 P Reversible hydration of carbon dioxide
LHDAJDNO_01508 3e-75 K helix_turn _helix lactose operon repressor
LHDAJDNO_01509 1.2e-241 ytfL P Transporter associated domain
LHDAJDNO_01510 2e-189 yddG EG EamA-like transporter family
LHDAJDNO_01511 1.9e-83 dps P Belongs to the Dps family
LHDAJDNO_01512 2.3e-136 S Protein of unknown function DUF45
LHDAJDNO_01513 3.4e-251 ulaA 2.7.1.194 S PTS system sugar-specific permease component
LHDAJDNO_01514 3.3e-40 ulaC 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
LHDAJDNO_01515 3.3e-77 ulaC 2.7.1.194, 2.7.1.197, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LHDAJDNO_01516 2.8e-188 K helix_turn _helix lactose operon repressor
LHDAJDNO_01517 0.0 G Glycosyl hydrolase family 20, domain 2
LHDAJDNO_01520 0.0 3.2.1.55 GH51 G arabinose metabolic process
LHDAJDNO_01521 2.5e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LHDAJDNO_01522 2.5e-124 gntR K FCD
LHDAJDNO_01523 2.3e-259 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
LHDAJDNO_01524 1.9e-24 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
LHDAJDNO_01527 9.4e-14 K Helix-turn-helix domain
LHDAJDNO_01528 3.4e-18 S Domain of unknown function (DUF4160)
LHDAJDNO_01529 9.6e-42 S Protein of unknown function (DUF2442)
LHDAJDNO_01530 6.7e-09 K helix_turn _helix lactose operon repressor
LHDAJDNO_01531 1.2e-227 I Serine aminopeptidase, S33
LHDAJDNO_01532 1.6e-187 K Periplasmic binding protein domain
LHDAJDNO_01533 7.9e-187 G Glycosyl hydrolases family 43
LHDAJDNO_01534 5.7e-21 abfA1 3.2.1.55 GH51 G arabinose metabolic process
LHDAJDNO_01535 6.7e-72 S Transmembrane domain of unknown function (DUF3566)
LHDAJDNO_01536 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LHDAJDNO_01537 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LHDAJDNO_01538 1.2e-87 S Protein of unknown function (DUF721)
LHDAJDNO_01539 1.2e-239 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LHDAJDNO_01540 6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LHDAJDNO_01541 2.8e-299 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LHDAJDNO_01542 4.5e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
LHDAJDNO_01543 1e-171 yidC U Membrane protein insertase, YidC Oxa1 family
LHDAJDNO_01544 8.6e-93 jag S Putative single-stranded nucleic acids-binding domain
LHDAJDNO_01545 1.3e-125 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
LHDAJDNO_01546 3.8e-179 parA D CobQ CobB MinD ParA nucleotide binding domain protein
LHDAJDNO_01547 4.4e-242 parB K Belongs to the ParB family
LHDAJDNO_01548 1e-202 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LHDAJDNO_01549 0.0 murJ KLT MviN-like protein
LHDAJDNO_01550 0.0 M Conserved repeat domain
LHDAJDNO_01551 5.2e-124 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
LHDAJDNO_01552 2.8e-279 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
LHDAJDNO_01553 6.7e-113 S LytR cell envelope-related transcriptional attenuator
LHDAJDNO_01554 9.3e-168 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LHDAJDNO_01555 8.2e-171 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LHDAJDNO_01556 1e-18 S G5
LHDAJDNO_01557 1.2e-155 L Phage integrase family
LHDAJDNO_01558 7.8e-131 fic D Fic/DOC family
LHDAJDNO_01559 3.3e-26
LHDAJDNO_01560 4.3e-27 L DNA integration
LHDAJDNO_01561 1.1e-24
LHDAJDNO_01562 5.8e-93
LHDAJDNO_01563 3.3e-115 O Subtilase family
LHDAJDNO_01565 6.4e-199 L Transposase, Mutator family
LHDAJDNO_01566 7.5e-183 lacR K Transcriptional regulator, LacI family
LHDAJDNO_01567 1.5e-61 nagA 3.5.1.25 G Amidohydrolase family
LHDAJDNO_01568 2.5e-20
LHDAJDNO_01570 5.6e-104
LHDAJDNO_01571 3.4e-40 ydzE EG EamA-like transporter family
LHDAJDNO_01572 4.1e-144 L IstB-like ATP binding protein
LHDAJDNO_01573 5.8e-296 L PFAM Integrase catalytic
LHDAJDNO_01574 2.2e-41 nrdH O Glutaredoxin
LHDAJDNO_01575 4.6e-168 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
LHDAJDNO_01576 7.5e-100 L Transposase and inactivated derivatives IS30 family
LHDAJDNO_01577 4.6e-37 XK27_00515 D Cell surface antigen C-terminus
LHDAJDNO_01578 3.2e-20 XK27_00515 D Cell surface antigen C-terminus
LHDAJDNO_01579 8.8e-16
LHDAJDNO_01582 4.6e-16
LHDAJDNO_01583 3e-43
LHDAJDNO_01584 4.4e-91 S Transcription factor WhiB
LHDAJDNO_01585 8.2e-117 parA D AAA domain
LHDAJDNO_01587 2.5e-60 L Initiator Replication protein
LHDAJDNO_01589 5.3e-51 S MobA/MobL family
LHDAJDNO_01590 9.1e-164 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, N-terminal domain
LHDAJDNO_01591 1.3e-235 iscS1 2.8.1.7 E Aminotransferase class-V
LHDAJDNO_01592 0.0 typA T Elongation factor G C-terminus
LHDAJDNO_01593 3.5e-78
LHDAJDNO_01594 1.2e-196 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
LHDAJDNO_01595 5.4e-192 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
LHDAJDNO_01596 7.3e-42
LHDAJDNO_01597 1.3e-187 xerC D Belongs to the 'phage' integrase family. XerC subfamily
LHDAJDNO_01598 7.9e-177 appB EP Binding-protein-dependent transport system inner membrane component
LHDAJDNO_01599 3.5e-166 dppC EP N-terminal TM domain of oligopeptide transport permease C
LHDAJDNO_01600 0.0 oppD P Belongs to the ABC transporter superfamily
LHDAJDNO_01601 0.0 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
LHDAJDNO_01602 5.2e-262 pepC 3.4.22.40 E Peptidase C1-like family
LHDAJDNO_01603 1.3e-170 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
LHDAJDNO_01604 3.2e-139 S Protein of unknown function (DUF3710)
LHDAJDNO_01605 1.4e-123 S Protein of unknown function (DUF3159)
LHDAJDNO_01606 2.9e-248 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LHDAJDNO_01607 1.2e-109
LHDAJDNO_01608 0.0 ctpE P E1-E2 ATPase
LHDAJDNO_01609 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LHDAJDNO_01611 2.5e-166 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
LHDAJDNO_01612 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
LHDAJDNO_01613 1.1e-53 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LHDAJDNO_01614 1.9e-220 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LHDAJDNO_01615 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LHDAJDNO_01616 3.2e-135 3.8.1.2 S Haloacid dehalogenase-like hydrolase
LHDAJDNO_01617 4.3e-183 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LHDAJDNO_01618 2.8e-137 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
LHDAJDNO_01619 0.0 arc O AAA ATPase forming ring-shaped complexes
LHDAJDNO_01620 0.0 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
LHDAJDNO_01621 5.7e-160 hisN 3.1.3.25 G Inositol monophosphatase family
LHDAJDNO_01622 9.2e-11 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
LHDAJDNO_01623 1.4e-275 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LHDAJDNO_01624 8.1e-42 hup L Belongs to the bacterial histone-like protein family
LHDAJDNO_01625 0.0 S Lysylphosphatidylglycerol synthase TM region
LHDAJDNO_01626 4.7e-279 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
LHDAJDNO_01627 8.3e-290 S PGAP1-like protein
LHDAJDNO_01629 2.8e-71
LHDAJDNO_01630 1.6e-148 S von Willebrand factor (vWF) type A domain
LHDAJDNO_01631 2.3e-190 S von Willebrand factor (vWF) type A domain
LHDAJDNO_01632 6.4e-94
LHDAJDNO_01633 7.2e-178 S Protein of unknown function DUF58
LHDAJDNO_01634 5e-196 moxR S ATPase family associated with various cellular activities (AAA)
LHDAJDNO_01635 1.1e-144 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LHDAJDNO_01636 3.4e-71 S LytR cell envelope-related transcriptional attenuator
LHDAJDNO_01637 2.2e-44 cspA K 'Cold-shock' DNA-binding domain
LHDAJDNO_01638 2.7e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LHDAJDNO_01639 1.7e-10 S Proteins of 100 residues with WXG
LHDAJDNO_01640 4.9e-162
LHDAJDNO_01641 1.6e-134 KT Response regulator receiver domain protein
LHDAJDNO_01642 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
LHDAJDNO_01643 5e-66 cspB K 'Cold-shock' DNA-binding domain
LHDAJDNO_01644 7.3e-192 S Protein of unknown function (DUF3027)
LHDAJDNO_01645 3e-184 uspA T Belongs to the universal stress protein A family
LHDAJDNO_01646 0.0 clpC O ATPase family associated with various cellular activities (AAA)
LHDAJDNO_01650 1.5e-216 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
LHDAJDNO_01651 7.1e-264 hisS 6.1.1.21 J Histidyl-tRNA synthetase
LHDAJDNO_01652 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LHDAJDNO_01653 6e-74 K helix_turn_helix, Lux Regulon
LHDAJDNO_01654 3.4e-91 S Aminoacyl-tRNA editing domain
LHDAJDNO_01655 1e-139 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
LHDAJDNO_01656 9.9e-152 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
LHDAJDNO_01657 1.9e-11 bioY S BioY family
LHDAJDNO_01658 4.8e-156 neo 2.7.1.87, 2.7.1.95 F Phosphotransferase enzyme family
LHDAJDNO_01659 7.6e-22 D Cell surface antigen C-terminus
LHDAJDNO_01660 6.1e-20 XK27_00515 D Cell surface antigen C-terminus
LHDAJDNO_01661 1.3e-17 traA L Conjugal transfer protein
LHDAJDNO_01662 8.6e-27 rom S Rop protein
LHDAJDNO_01663 6.7e-43 I alpha/beta hydrolase fold
LHDAJDNO_01664 3.8e-24 rarD S Rard protein
LHDAJDNO_01665 4.1e-89 rarD 3.4.17.13 E Rard protein
LHDAJDNO_01666 4.2e-29
LHDAJDNO_01667 8.4e-222 L Uncharacterized conserved protein (DUF2075)
LHDAJDNO_01668 4.2e-53 V Abi-like protein
LHDAJDNO_01669 1.2e-185 L Transposase
LHDAJDNO_01670 4.2e-40 L Helix-turn-helix domain
LHDAJDNO_01671 6.3e-187 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
LHDAJDNO_01672 2.1e-111 S Sel1-like repeats.
LHDAJDNO_01673 6.9e-159 ybeM S Carbon-nitrogen hydrolase
LHDAJDNO_01674 3.6e-182 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
LHDAJDNO_01675 5.6e-244 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
LHDAJDNO_01676 3.6e-82
LHDAJDNO_01677 2.7e-304 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
LHDAJDNO_01678 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
LHDAJDNO_01679 0.0 tetP J Elongation factor G, domain IV
LHDAJDNO_01680 2.3e-287 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
LHDAJDNO_01681 7.5e-107 V ATPases associated with a variety of cellular activities
LHDAJDNO_01682 4.9e-186
LHDAJDNO_01683 2.1e-106 K Cro/C1-type HTH DNA-binding domain
LHDAJDNO_01684 4.4e-175 L Replication initiation factor
LHDAJDNO_01685 1e-20 xis S Excisionase from transposon Tn916
LHDAJDNO_01686 1.3e-170 L Phage integrase family
LHDAJDNO_01687 4e-13 S Membrane
LHDAJDNO_01688 3e-246 hemN H Involved in the biosynthesis of porphyrin-containing compound
LHDAJDNO_01689 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LHDAJDNO_01690 9.9e-34 rpsT J Binds directly to 16S ribosomal RNA
LHDAJDNO_01691 1.2e-135 S UPF0126 domain
LHDAJDNO_01692 2.7e-99 3.1.4.37 T RNA ligase
LHDAJDNO_01693 4e-46 S phosphoesterase or phosphohydrolase
LHDAJDNO_01694 2.4e-225 ilvE 2.6.1.42 E Amino-transferase class IV
LHDAJDNO_01695 8.3e-95 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LHDAJDNO_01696 4.8e-190 S alpha beta
LHDAJDNO_01697 2.3e-233 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LHDAJDNO_01698 4.4e-44 pntA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
LHDAJDNO_01699 1.1e-201 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
LHDAJDNO_01700 0.0 fadD 6.2.1.3 I AMP-binding enzyme
LHDAJDNO_01701 3.3e-186 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LHDAJDNO_01702 2.7e-250 corC S CBS domain
LHDAJDNO_01703 7.4e-100 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LHDAJDNO_01704 3.4e-197 phoH T PhoH-like protein
LHDAJDNO_01705 4.4e-58 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
LHDAJDNO_01706 2.1e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LHDAJDNO_01708 4e-164 spoU 2.1.1.185 J SpoU rRNA Methylase family
LHDAJDNO_01709 4.7e-243 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LHDAJDNO_01710 9.7e-106 yitW S Iron-sulfur cluster assembly protein
LHDAJDNO_01711 8.8e-101 iscU C SUF system FeS assembly protein, NifU family
LHDAJDNO_01712 1.6e-241 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LHDAJDNO_01713 1.4e-144 sufC O FeS assembly ATPase SufC
LHDAJDNO_01714 2.6e-233 sufD O FeS assembly protein SufD
LHDAJDNO_01715 3.6e-290 sufB O FeS assembly protein SufB
LHDAJDNO_01716 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LHDAJDNO_01717 6.8e-08 3.4.22.70 M Sortase family
LHDAJDNO_01718 1.4e-119 K helix_turn_helix, Lux Regulon
LHDAJDNO_01719 3.4e-15
LHDAJDNO_01720 2.2e-78 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
LHDAJDNO_01721 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LHDAJDNO_01722 1.6e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LHDAJDNO_01723 4.8e-47 3.4.23.43 S Type IV leader peptidase family
LHDAJDNO_01724 7.1e-188 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LHDAJDNO_01725 3e-75 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LHDAJDNO_01726 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LHDAJDNO_01727 1.1e-36
LHDAJDNO_01728 3.8e-64 WQ51_05790 S Bacterial protein of unknown function (DUF948)
LHDAJDNO_01729 1.5e-135 pgm3 G Phosphoglycerate mutase family
LHDAJDNO_01730 2.2e-66 oatA I Psort location CytoplasmicMembrane, score 9.99
LHDAJDNO_01731 7.5e-146 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LHDAJDNO_01732 4.1e-103 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
LHDAJDNO_01733 5.7e-30
LHDAJDNO_01734 5.9e-310 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
LHDAJDNO_01735 7.7e-247
LHDAJDNO_01736 8.3e-168 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LHDAJDNO_01737 1.1e-225 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
LHDAJDNO_01738 5.5e-101 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LHDAJDNO_01739 2.6e-44 yajC U Preprotein translocase subunit
LHDAJDNO_01740 1.8e-201 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LHDAJDNO_01741 2.5e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LHDAJDNO_01742 1.8e-99 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LHDAJDNO_01743 1e-131 yebC K transcriptional regulatory protein
LHDAJDNO_01744 0.0 3.2.1.52 GH20 M Glycosyl hydrolase family 20, catalytic domain
LHDAJDNO_01745 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LHDAJDNO_01746 2.2e-250 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LHDAJDNO_01749 9.4e-257
LHDAJDNO_01753 2.8e-156 S PAC2 family
LHDAJDNO_01754 3.2e-167 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
LHDAJDNO_01755 2.1e-159 G Fructosamine kinase
LHDAJDNO_01756 3.4e-211 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LHDAJDNO_01757 2.5e-207 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LHDAJDNO_01758 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
LHDAJDNO_01759 1e-201 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LHDAJDNO_01760 3.1e-142 yoaK S Protein of unknown function (DUF1275)
LHDAJDNO_01761 3.7e-252 brnQ U Component of the transport system for branched-chain amino acids
LHDAJDNO_01762 1.2e-239 mepA_6 V MatE
LHDAJDNO_01763 6.1e-162 S Sucrose-6F-phosphate phosphohydrolase
LHDAJDNO_01764 3.1e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
LHDAJDNO_01765 8e-33 secG U Preprotein translocase SecG subunit
LHDAJDNO_01766 5.3e-147 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LHDAJDNO_01767 2.4e-220 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
LHDAJDNO_01768 2.2e-171 whiA K May be required for sporulation
LHDAJDNO_01769 2.6e-177 rapZ S Displays ATPase and GTPase activities
LHDAJDNO_01770 4.3e-183 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
LHDAJDNO_01771 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LHDAJDNO_01772 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LHDAJDNO_01773 1.4e-76
LHDAJDNO_01774 5.6e-60 V MacB-like periplasmic core domain
LHDAJDNO_01775 2.1e-117 K Transcriptional regulatory protein, C terminal
LHDAJDNO_01776 2.2e-239 qseC 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
LHDAJDNO_01777 2.2e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
LHDAJDNO_01778 2.6e-302 ybiT S ABC transporter
LHDAJDNO_01779 8.5e-198 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LHDAJDNO_01780 1.1e-307 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
LHDAJDNO_01781 2.8e-207 mdsC 2.7.1.162, 2.7.1.39 S Phosphotransferase enzyme family
LHDAJDNO_01782 6.4e-218 GK ROK family
LHDAJDNO_01783 6.9e-178 2.7.1.2 GK ROK family
LHDAJDNO_01784 5.3e-158 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
LHDAJDNO_01785 3.1e-60 S competence protein
LHDAJDNO_01786 2.6e-119 dprA LU DNA recombination-mediator protein A
LHDAJDNO_01787 6.8e-08 int L Phage integrase, N-terminal SAM-like domain
LHDAJDNO_01788 9.7e-30
LHDAJDNO_01789 1.7e-27 S Protein of unknown function (DUF3800)
LHDAJDNO_01790 3.1e-194 int L Phage integrase, N-terminal SAM-like domain
LHDAJDNO_01791 1.2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LHDAJDNO_01792 5.4e-228 mtnE 2.6.1.83 E Aminotransferase class I and II
LHDAJDNO_01793 2.9e-93 metI P Binding-protein-dependent transport system inner membrane component
LHDAJDNO_01794 4.4e-203 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LHDAJDNO_01795 3.9e-182 1.2.4.1 C Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
LHDAJDNO_01796 5.9e-188 acoA 1.2.4.1 C Dehydrogenase E1 component
LHDAJDNO_01797 3.2e-147 P NLPA lipoprotein
LHDAJDNO_01798 1.3e-168 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
LHDAJDNO_01799 6.1e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LHDAJDNO_01800 6.5e-265 pip 3.4.11.5 S alpha/beta hydrolase fold
LHDAJDNO_01801 0.0 tcsS2 T Histidine kinase
LHDAJDNO_01802 6.1e-132 K helix_turn_helix, Lux Regulon
LHDAJDNO_01803 0.0 phoN I PAP2 superfamily
LHDAJDNO_01804 0.0 MV MacB-like periplasmic core domain
LHDAJDNO_01805 3.4e-162 V ABC transporter, ATP-binding protein
LHDAJDNO_01806 2.6e-252 metY 2.5.1.49 E Aminotransferase class-V
LHDAJDNO_01807 2.1e-157 S Putative ABC-transporter type IV
LHDAJDNO_01808 1.5e-166 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
LHDAJDNO_01809 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
LHDAJDNO_01810 3.3e-283 dprA 5.99.1.2 LU DNA recombination-mediator protein A
LHDAJDNO_01811 1.9e-294 comM O Magnesium chelatase, subunit ChlI C-terminal
LHDAJDNO_01812 3e-71 yraN L Belongs to the UPF0102 family
LHDAJDNO_01813 4.6e-185 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
LHDAJDNO_01814 1.1e-118 safC S O-methyltransferase
LHDAJDNO_01815 8.4e-168 fmt2 3.2.2.10 S Belongs to the LOG family
LHDAJDNO_01816 1.2e-225 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LHDAJDNO_01817 1e-234 patB 4.4.1.8 E Aminotransferase, class I II
LHDAJDNO_01819 5.9e-244 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LHDAJDNO_01820 1.5e-127 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LHDAJDNO_01821 1.1e-112 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LHDAJDNO_01822 3.6e-255 clcA_2 P Voltage gated chloride channel
LHDAJDNO_01823 2.8e-236 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LHDAJDNO_01824 2.4e-250 rnd 3.1.13.5 J 3'-5' exonuclease
LHDAJDNO_01825 8.3e-113 S Protein of unknown function (DUF3000)
LHDAJDNO_01826 3.9e-175 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LHDAJDNO_01827 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
LHDAJDNO_01828 1.9e-39
LHDAJDNO_01829 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LHDAJDNO_01830 2.7e-224 S Peptidase dimerisation domain
LHDAJDNO_01831 2.1e-94 P ABC-type metal ion transport system permease component
LHDAJDNO_01832 5.5e-166 S Sucrose-6F-phosphate phosphohydrolase
LHDAJDNO_01833 7.1e-103 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LHDAJDNO_01834 5.1e-07
LHDAJDNO_01835 9.5e-35

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)