ORF_ID e_value Gene_name EC_number CAZy COGs Description
BPHMMAGG_00001 1.8e-196 EGP Major facilitator Superfamily
BPHMMAGG_00002 4.7e-35
BPHMMAGG_00003 1.3e-99 K DNA-templated transcription, initiation
BPHMMAGG_00004 6.1e-29
BPHMMAGG_00006 4.6e-48 L Integrase
BPHMMAGG_00007 3.7e-265 L PFAM Integrase catalytic region
BPHMMAGG_00008 1.2e-230 L Integrase core domain
BPHMMAGG_00009 5.9e-238 L Integrase core domain
BPHMMAGG_00010 2.4e-08 D FIVAR domain
BPHMMAGG_00011 1e-09 D Domain of Unknown Function (DUF1542)
BPHMMAGG_00013 3.4e-80 L An automated process has identified a potential problem with this gene model
BPHMMAGG_00014 1.7e-129 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
BPHMMAGG_00015 6e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
BPHMMAGG_00016 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
BPHMMAGG_00017 5.5e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BPHMMAGG_00018 2e-203 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
BPHMMAGG_00019 3.8e-34 yaaA S S4 domain protein YaaA
BPHMMAGG_00020 1.3e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BPHMMAGG_00021 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BPHMMAGG_00022 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BPHMMAGG_00023 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
BPHMMAGG_00024 2.8e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
BPHMMAGG_00025 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BPHMMAGG_00026 5.3e-74 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BPHMMAGG_00027 2.6e-100 deoR K sugar-binding domain protein
BPHMMAGG_00028 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
BPHMMAGG_00029 2e-74 rplI J Binds to the 23S rRNA
BPHMMAGG_00030 1.8e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
BPHMMAGG_00031 9e-207 yttB EGP Major facilitator Superfamily
BPHMMAGG_00032 9.1e-61
BPHMMAGG_00033 6.9e-156 S Polyphosphate nucleotide phosphotransferase, PPK2 family
BPHMMAGG_00035 2.2e-95 Z012_01130 S Fic/DOC family
BPHMMAGG_00037 6.8e-72 K helix_turn_helix multiple antibiotic resistance protein
BPHMMAGG_00038 7.6e-308 lmrA 3.6.3.44 V ABC transporter
BPHMMAGG_00041 3.1e-130 K response regulator
BPHMMAGG_00042 0.0 vicK 2.7.13.3 T Histidine kinase
BPHMMAGG_00043 2.4e-245 yycH S YycH protein
BPHMMAGG_00044 7.8e-149 yycI S YycH protein
BPHMMAGG_00045 2.3e-153 vicX 3.1.26.11 S domain protein
BPHMMAGG_00046 1.6e-214 htrA 3.4.21.107 O serine protease
BPHMMAGG_00047 2.3e-84 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
BPHMMAGG_00048 1.9e-178 ABC-SBP S ABC transporter
BPHMMAGG_00049 4.7e-88 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BPHMMAGG_00051 2.9e-96 S reductase
BPHMMAGG_00052 4.9e-226 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
BPHMMAGG_00053 2.5e-27
BPHMMAGG_00054 3.1e-41
BPHMMAGG_00055 1.3e-27
BPHMMAGG_00056 7.1e-59 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
BPHMMAGG_00057 3.5e-112 L Initiator Replication protein
BPHMMAGG_00059 3.1e-156 L An automated process has identified a potential problem with this gene model
BPHMMAGG_00060 1.3e-184 L Transposase IS66 family
BPHMMAGG_00061 2.9e-54 L Transposase IS66 family
BPHMMAGG_00065 1.3e-263 dtpT U amino acid peptide transporter
BPHMMAGG_00066 9.1e-150 yjjH S Calcineurin-like phosphoesterase
BPHMMAGG_00069 8.5e-111
BPHMMAGG_00070 1.1e-248 EGP Major facilitator Superfamily
BPHMMAGG_00071 1e-301 aspT P Predicted Permease Membrane Region
BPHMMAGG_00072 2.2e-131 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
BPHMMAGG_00073 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
BPHMMAGG_00074 3.1e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BPHMMAGG_00075 5.7e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
BPHMMAGG_00076 0.0 yhgF K Tex-like protein N-terminal domain protein
BPHMMAGG_00077 8.1e-84 ydcK S Belongs to the SprT family
BPHMMAGG_00079 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
BPHMMAGG_00080 8.5e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
BPHMMAGG_00081 0.0 S Bacterial membrane protein, YfhO
BPHMMAGG_00082 3e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BPHMMAGG_00083 4.5e-168 I alpha/beta hydrolase fold
BPHMMAGG_00084 1.1e-214 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
BPHMMAGG_00085 3.2e-119 tcyB E ABC transporter
BPHMMAGG_00086 8.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
BPHMMAGG_00087 1.8e-139 tcyA ET Belongs to the bacterial solute-binding protein 3 family
BPHMMAGG_00088 6.6e-267 pepC 3.4.22.40 E Peptidase C1-like family
BPHMMAGG_00089 1.3e-125 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BPHMMAGG_00090 5.5e-49 HA62_12640 S GCN5-related N-acetyl-transferase
BPHMMAGG_00091 7.3e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
BPHMMAGG_00092 5e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BPHMMAGG_00093 4.7e-205 yacL S domain protein
BPHMMAGG_00094 4.7e-271 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
BPHMMAGG_00095 2.1e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BPHMMAGG_00096 4.7e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BPHMMAGG_00097 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
BPHMMAGG_00098 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
BPHMMAGG_00099 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
BPHMMAGG_00100 2.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BPHMMAGG_00101 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
BPHMMAGG_00102 5.6e-225 aadAT EK Aminotransferase, class I
BPHMMAGG_00104 6.7e-19 M Glycosyl transferase family group 2
BPHMMAGG_00105 1.5e-178 M Glycosyl transferase family group 2
BPHMMAGG_00106 4.4e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
BPHMMAGG_00107 4.9e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BPHMMAGG_00108 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
BPHMMAGG_00109 2e-26
BPHMMAGG_00111 3.2e-38 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
BPHMMAGG_00112 5.2e-23 K transcriptional regulator PadR family
BPHMMAGG_00113 7.9e-14
BPHMMAGG_00114 2.6e-74 copB 3.6.3.4 P P-type ATPase
BPHMMAGG_00115 1.7e-65 XK27_01125 L PFAM IS66 Orf2 family protein
BPHMMAGG_00117 4.8e-44 T Antidote-toxin recognition MazE, bacterial antitoxin
BPHMMAGG_00118 1.9e-121 O Bacterial dnaA protein
BPHMMAGG_00119 3.5e-50 1.6.5.2 GM NAD(P)H-binding
BPHMMAGG_00120 3.8e-73 K Transcriptional regulator
BPHMMAGG_00121 1.6e-163 proX M ABC transporter, substrate-binding protein, QAT family
BPHMMAGG_00122 2.4e-108 proWZ P ABC transporter permease
BPHMMAGG_00123 1.8e-139 proV E ABC transporter, ATP-binding protein
BPHMMAGG_00124 2.1e-101 proW P ABC transporter, permease protein
BPHMMAGG_00125 2e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
BPHMMAGG_00126 3.2e-125 clcA P chloride
BPHMMAGG_00127 5.5e-214 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
BPHMMAGG_00128 3.1e-103 metI P ABC transporter permease
BPHMMAGG_00129 1.4e-190 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BPHMMAGG_00130 1.4e-153 metQ1 P Belongs to the nlpA lipoprotein family
BPHMMAGG_00131 8.9e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
BPHMMAGG_00132 3.7e-221 norA EGP Major facilitator Superfamily
BPHMMAGG_00133 8.9e-41 1.3.5.4 S FMN binding
BPHMMAGG_00134 2.7e-117 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BPHMMAGG_00135 6.4e-263 yfnA E amino acid
BPHMMAGG_00136 2.9e-232 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BPHMMAGG_00138 5e-202 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
BPHMMAGG_00139 0.0 helD 3.6.4.12 L DNA helicase
BPHMMAGG_00140 6.3e-81 ndk 2.7.4.6 F Belongs to the NDK family
BPHMMAGG_00141 2.1e-182 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
BPHMMAGG_00142 2.9e-190 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
BPHMMAGG_00143 2.7e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
BPHMMAGG_00144 3.8e-224 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
BPHMMAGG_00145 8.6e-176
BPHMMAGG_00146 4e-130 cobB K SIR2 family
BPHMMAGG_00147 1.2e-160 yunF F Protein of unknown function DUF72
BPHMMAGG_00148 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BPHMMAGG_00149 3.5e-154 tatD L hydrolase, TatD family
BPHMMAGG_00150 8e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BPHMMAGG_00151 9.5e-161 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
BPHMMAGG_00152 6.8e-37 veg S Biofilm formation stimulator VEG
BPHMMAGG_00153 2.6e-160 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BPHMMAGG_00154 4e-167 znuA P Belongs to the bacterial solute-binding protein 9 family
BPHMMAGG_00155 2.2e-122 fhuC P ABC transporter
BPHMMAGG_00156 4.7e-127 znuB U ABC 3 transport family
BPHMMAGG_00157 6.9e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
BPHMMAGG_00158 1e-238 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BPHMMAGG_00159 4.2e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BPHMMAGG_00160 9e-48
BPHMMAGG_00161 2.1e-146 yxeH S hydrolase
BPHMMAGG_00162 1e-270 ywfO S HD domain protein
BPHMMAGG_00163 1.8e-145 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
BPHMMAGG_00164 1.4e-84
BPHMMAGG_00165 4.1e-33 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BPHMMAGG_00166 2.4e-08 map 3.4.11.18 E Methionine Aminopeptidase
BPHMMAGG_00167 1.3e-57 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
BPHMMAGG_00168 1.7e-106 L hmm pf00665
BPHMMAGG_00171 2.1e-103 K Transcriptional regulator
BPHMMAGG_00172 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
BPHMMAGG_00173 2.4e-53 ysxB J Cysteine protease Prp
BPHMMAGG_00174 1.3e-44 rpmA J Belongs to the bacterial ribosomal protein bL27 family
BPHMMAGG_00175 5.8e-129 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BPHMMAGG_00176 3.3e-200 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
BPHMMAGG_00177 1.7e-114 J 2'-5' RNA ligase superfamily
BPHMMAGG_00178 2.2e-70 yqhY S Asp23 family, cell envelope-related function
BPHMMAGG_00179 6.8e-69 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BPHMMAGG_00180 8.8e-148 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BPHMMAGG_00181 1.2e-215 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
BPHMMAGG_00182 1.3e-42 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
BPHMMAGG_00183 4.9e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
BPHMMAGG_00184 1.7e-148 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
BPHMMAGG_00185 7.3e-77 argR K Regulates arginine biosynthesis genes
BPHMMAGG_00186 3.6e-262 recN L May be involved in recombinational repair of damaged DNA
BPHMMAGG_00187 4.2e-53
BPHMMAGG_00188 1.3e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
BPHMMAGG_00189 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
BPHMMAGG_00190 5.3e-207 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BPHMMAGG_00191 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BPHMMAGG_00192 1.4e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BPHMMAGG_00193 9e-248 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BPHMMAGG_00194 2.1e-129 stp 3.1.3.16 T phosphatase
BPHMMAGG_00195 0.0 KLT serine threonine protein kinase
BPHMMAGG_00196 1.1e-161 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
BPHMMAGG_00197 4.7e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
BPHMMAGG_00198 4.5e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
BPHMMAGG_00199 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
BPHMMAGG_00200 8.8e-57 asp S Asp23 family, cell envelope-related function
BPHMMAGG_00201 0.0 yloV S DAK2 domain fusion protein YloV
BPHMMAGG_00202 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BPHMMAGG_00203 1e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
BPHMMAGG_00204 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
BPHMMAGG_00205 1.2e-131 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
BPHMMAGG_00206 0.0 smc D Required for chromosome condensation and partitioning
BPHMMAGG_00207 1.1e-177 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
BPHMMAGG_00208 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BPHMMAGG_00209 1.5e-248 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BPHMMAGG_00210 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
BPHMMAGG_00211 4.6e-39 ylqC S Belongs to the UPF0109 family
BPHMMAGG_00212 7.6e-91 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BPHMMAGG_00213 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
BPHMMAGG_00214 1.7e-260 yfnA E amino acid
BPHMMAGG_00215 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
BPHMMAGG_00216 2e-55 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
BPHMMAGG_00217 1e-96 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
BPHMMAGG_00218 6.2e-20 wzb 3.1.3.48 T Tyrosine phosphatase family
BPHMMAGG_00219 7.6e-09
BPHMMAGG_00220 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
BPHMMAGG_00221 5.2e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BPHMMAGG_00222 3.7e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
BPHMMAGG_00223 1.1e-155 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
BPHMMAGG_00224 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
BPHMMAGG_00225 9.2e-92 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BPHMMAGG_00226 2.5e-88
BPHMMAGG_00228 3.9e-127 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BPHMMAGG_00229 6e-208 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
BPHMMAGG_00230 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BPHMMAGG_00231 1.3e-35 ynzC S UPF0291 protein
BPHMMAGG_00232 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
BPHMMAGG_00233 1.6e-117 plsC 2.3.1.51 I Acyltransferase
BPHMMAGG_00234 5.4e-141 yabB 2.1.1.223 L Methyltransferase small domain
BPHMMAGG_00235 5.4e-49 yazA L GIY-YIG catalytic domain protein
BPHMMAGG_00236 5.9e-180 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BPHMMAGG_00237 4.6e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
BPHMMAGG_00238 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BPHMMAGG_00239 4.1e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
BPHMMAGG_00240 4.8e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
BPHMMAGG_00241 1e-139 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BPHMMAGG_00242 7.6e-138 cdsA 2.7.7.41 I Belongs to the CDS family
BPHMMAGG_00243 1.1e-234 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
BPHMMAGG_00244 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
BPHMMAGG_00245 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BPHMMAGG_00246 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
BPHMMAGG_00247 1.4e-215 nusA K Participates in both transcription termination and antitermination
BPHMMAGG_00248 1e-44 ylxR K Protein of unknown function (DUF448)
BPHMMAGG_00249 1.3e-48 ylxQ J ribosomal protein
BPHMMAGG_00250 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BPHMMAGG_00251 6.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BPHMMAGG_00252 4.2e-164 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BPHMMAGG_00253 1.9e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
BPHMMAGG_00254 7.6e-64
BPHMMAGG_00255 5.9e-194 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
BPHMMAGG_00256 3.9e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BPHMMAGG_00257 0.0 dnaK O Heat shock 70 kDa protein
BPHMMAGG_00258 5.1e-199 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
BPHMMAGG_00259 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
BPHMMAGG_00261 2e-70 padR K Virulence activator alpha C-term
BPHMMAGG_00262 1e-79 P Major Facilitator Superfamily
BPHMMAGG_00264 1e-23
BPHMMAGG_00265 3.1e-101 V VanZ like family
BPHMMAGG_00266 2.2e-230 cycA E Amino acid permease
BPHMMAGG_00267 2.8e-84 perR P Belongs to the Fur family
BPHMMAGG_00268 7.9e-258 EGP Major facilitator Superfamily
BPHMMAGG_00269 6.7e-93 tag 3.2.2.20 L glycosylase
BPHMMAGG_00270 1.9e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BPHMMAGG_00271 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
BPHMMAGG_00272 4.9e-41
BPHMMAGG_00273 3.5e-302 ytgP S Polysaccharide biosynthesis protein
BPHMMAGG_00274 5.9e-152 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BPHMMAGG_00275 1.1e-275 pepV 3.5.1.18 E dipeptidase PepV
BPHMMAGG_00276 7.3e-86 uspA T Belongs to the universal stress protein A family
BPHMMAGG_00277 3.2e-176 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
BPHMMAGG_00278 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
BPHMMAGG_00279 7.2e-112
BPHMMAGG_00280 8.7e-187 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
BPHMMAGG_00281 1.4e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BPHMMAGG_00282 1.8e-31
BPHMMAGG_00283 2.3e-108 S CAAX protease self-immunity
BPHMMAGG_00284 1.9e-43
BPHMMAGG_00286 2e-67
BPHMMAGG_00287 2.6e-55 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BPHMMAGG_00288 2.9e-90 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
BPHMMAGG_00289 2.6e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
BPHMMAGG_00290 1.4e-221 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
BPHMMAGG_00291 5.4e-104 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
BPHMMAGG_00292 5.6e-214 folP 2.5.1.15 H dihydropteroate synthase
BPHMMAGG_00293 1.4e-43
BPHMMAGG_00294 1.3e-36
BPHMMAGG_00296 1.6e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
BPHMMAGG_00297 7.3e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
BPHMMAGG_00298 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
BPHMMAGG_00299 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
BPHMMAGG_00300 9.4e-38 yheA S Belongs to the UPF0342 family
BPHMMAGG_00301 1.2e-219 yhaO L Ser Thr phosphatase family protein
BPHMMAGG_00302 0.0 L AAA domain
BPHMMAGG_00303 8.5e-128 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
BPHMMAGG_00305 4.1e-77 hit FG histidine triad
BPHMMAGG_00306 1.8e-136 ecsA V ABC transporter, ATP-binding protein
BPHMMAGG_00307 9.6e-217 ecsB U ABC transporter
BPHMMAGG_00308 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
BPHMMAGG_00309 8.2e-23 S YSIRK type signal peptide
BPHMMAGG_00310 6.6e-99 2.7.13.3 T GHKL domain
BPHMMAGG_00311 2e-09 IQ KR domain
BPHMMAGG_00312 7.9e-88 IQ KR domain
BPHMMAGG_00313 2.1e-132 S membrane transporter protein
BPHMMAGG_00314 1.3e-96 S ABC-type cobalt transport system, permease component
BPHMMAGG_00315 4.9e-249 cbiO1 S ABC transporter, ATP-binding protein
BPHMMAGG_00316 6.6e-111 P Cobalt transport protein
BPHMMAGG_00317 1.6e-52 yvlA
BPHMMAGG_00318 0.0 yjcE P Sodium proton antiporter
BPHMMAGG_00319 6.4e-52 ypaA S Protein of unknown function (DUF1304)
BPHMMAGG_00320 2e-172 D Alpha beta
BPHMMAGG_00321 1e-72 K Transcriptional regulator
BPHMMAGG_00322 1e-159
BPHMMAGG_00323 4.5e-86 1.6.5.5 C Zinc-binding dehydrogenase
BPHMMAGG_00324 9.8e-23 1.6.5.5 C Zinc-binding dehydrogenase
BPHMMAGG_00325 7.2e-256 G PTS system Galactitol-specific IIC component
BPHMMAGG_00326 2.6e-211 EGP Major facilitator Superfamily
BPHMMAGG_00327 1.1e-134 V ABC transporter
BPHMMAGG_00328 1.8e-38
BPHMMAGG_00329 5.8e-59
BPHMMAGG_00330 4e-14
BPHMMAGG_00331 7.1e-63
BPHMMAGG_00332 6.7e-195 lplA 6.3.1.20 H Lipoate-protein ligase
BPHMMAGG_00333 5.1e-81 uspA T universal stress protein
BPHMMAGG_00334 0.0 tetP J elongation factor G
BPHMMAGG_00335 2.9e-165 GK ROK family
BPHMMAGG_00336 1.6e-236 brnQ U Component of the transport system for branched-chain amino acids
BPHMMAGG_00337 1.2e-137 aroD S Serine hydrolase (FSH1)
BPHMMAGG_00338 1.2e-236 yagE E amino acid
BPHMMAGG_00339 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
BPHMMAGG_00340 4.7e-126 gntR K UbiC transcription regulator-associated domain protein
BPHMMAGG_00341 1.6e-85 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BPHMMAGG_00342 2.6e-269 pipD E Dipeptidase
BPHMMAGG_00343 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
BPHMMAGG_00344 0.0 yfiC V ABC transporter
BPHMMAGG_00345 1.7e-286 lmrA V ABC transporter, ATP-binding protein
BPHMMAGG_00346 1.7e-17 K Winged helix DNA-binding domain
BPHMMAGG_00347 1.6e-178 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BPHMMAGG_00348 2.9e-19 S PFAM Archaeal ATPase
BPHMMAGG_00349 5.9e-73 S ECF transporter, substrate-specific component
BPHMMAGG_00350 9.8e-51 S Domain of unknown function (DUF4430)
BPHMMAGG_00351 5.2e-17 cnrT EG PFAM EamA-like transporter family
BPHMMAGG_00352 8.6e-20 cnrT EG PFAM EamA-like transporter family
BPHMMAGG_00353 4.5e-55 yfbR S HD containing hydrolase-like enzyme
BPHMMAGG_00354 4.7e-28 bglP 2.7.1.193, 2.7.1.211 G phosphotransferase system
BPHMMAGG_00356 6.9e-41 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BPHMMAGG_00357 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
BPHMMAGG_00358 8.5e-254 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BPHMMAGG_00359 1.3e-125 ybbR S YbbR-like protein
BPHMMAGG_00360 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BPHMMAGG_00361 3.7e-249 fucP G Major Facilitator Superfamily
BPHMMAGG_00362 5.1e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
BPHMMAGG_00363 6.1e-163 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BPHMMAGG_00364 3e-167 murB 1.3.1.98 M Cell wall formation
BPHMMAGG_00365 2.7e-102 dnaQ 2.7.7.7 L DNA polymerase III
BPHMMAGG_00366 4.4e-76 S PAS domain
BPHMMAGG_00367 2.3e-87 K Acetyltransferase (GNAT) domain
BPHMMAGG_00368 2e-80 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
BPHMMAGG_00369 3.2e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
BPHMMAGG_00370 2.6e-134 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BPHMMAGG_00371 6.3e-105 yxjI
BPHMMAGG_00372 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
BPHMMAGG_00373 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
BPHMMAGG_00374 2.2e-131 est 3.1.1.1 S Serine aminopeptidase, S33
BPHMMAGG_00375 1.8e-34 secG U Preprotein translocase
BPHMMAGG_00376 2.4e-292 clcA P chloride
BPHMMAGG_00377 1.2e-244 yifK E Amino acid permease
BPHMMAGG_00378 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
BPHMMAGG_00379 1.8e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
BPHMMAGG_00380 1.2e-227 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
BPHMMAGG_00381 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
BPHMMAGG_00383 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
BPHMMAGG_00384 2.4e-131 glpT G Major Facilitator Superfamily
BPHMMAGG_00385 1.5e-71 glpT G Major Facilitator Superfamily
BPHMMAGG_00386 8.8e-15
BPHMMAGG_00388 1.5e-169 whiA K May be required for sporulation
BPHMMAGG_00389 2.1e-185 ybhK S Required for morphogenesis under gluconeogenic growth conditions
BPHMMAGG_00390 4.9e-162 rapZ S Displays ATPase and GTPase activities
BPHMMAGG_00391 1.6e-244 steT E amino acid
BPHMMAGG_00392 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
BPHMMAGG_00393 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
BPHMMAGG_00394 8.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BPHMMAGG_00395 7.2e-86 spxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
BPHMMAGG_00396 5.6e-89 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
BPHMMAGG_00397 2.3e-56 L PFAM Integrase catalytic region
BPHMMAGG_00398 1.6e-17 plnA
BPHMMAGG_00399 5.5e-161 degV S EDD domain protein, DegV family
BPHMMAGG_00400 1.1e-89
BPHMMAGG_00401 1.4e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
BPHMMAGG_00402 4.6e-157 gspA M family 8
BPHMMAGG_00403 1.4e-153 S Alpha beta hydrolase
BPHMMAGG_00404 1.5e-94 K Acetyltransferase (GNAT) domain
BPHMMAGG_00405 4.8e-64 XK27_08635 S UPF0210 protein
BPHMMAGG_00406 4.4e-73 XK27_08635 S UPF0210 protein
BPHMMAGG_00407 1.5e-41 XK27_08635 S UPF0210 protein
BPHMMAGG_00408 3.3e-166 1.1.1.346 C Aldo keto reductase
BPHMMAGG_00409 1.7e-157 K LysR substrate binding domain protein
BPHMMAGG_00410 6.7e-81 C Flavodoxin
BPHMMAGG_00411 4e-78 yphH S Cupin domain
BPHMMAGG_00412 3.8e-73 yeaL S UPF0756 membrane protein
BPHMMAGG_00413 2.6e-242 EGP Major facilitator Superfamily
BPHMMAGG_00414 5e-75 copY K Copper transport repressor CopY TcrY
BPHMMAGG_00415 8.5e-246 yhdP S Transporter associated domain
BPHMMAGG_00416 0.0 ubiB S ABC1 family
BPHMMAGG_00417 8.7e-145 S DUF218 domain
BPHMMAGG_00418 2.1e-67 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
BPHMMAGG_00419 1.6e-56 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BPHMMAGG_00420 4.5e-55 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BPHMMAGG_00421 0.0 uvrA3 L excinuclease ABC, A subunit
BPHMMAGG_00422 4.3e-121 S SNARE associated Golgi protein
BPHMMAGG_00423 2.3e-229 N Uncharacterized conserved protein (DUF2075)
BPHMMAGG_00424 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BPHMMAGG_00426 1.5e-253 yifK E Amino acid permease
BPHMMAGG_00427 7.2e-158 endA V DNA/RNA non-specific endonuclease
BPHMMAGG_00428 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BPHMMAGG_00429 2.3e-41 ybaN S Protein of unknown function (DUF454)
BPHMMAGG_00430 4.5e-71 S Protein of unknown function (DUF3290)
BPHMMAGG_00431 4.7e-114 yviA S Protein of unknown function (DUF421)
BPHMMAGG_00432 2.8e-162 S Alpha/beta hydrolase of unknown function (DUF915)
BPHMMAGG_00433 2e-18
BPHMMAGG_00434 2.1e-90 ntd 2.4.2.6 F Nucleoside
BPHMMAGG_00435 3.3e-152 3.1.3.102, 3.1.3.104 S hydrolase
BPHMMAGG_00436 8.9e-41 yrvD S Pfam:DUF1049
BPHMMAGG_00438 3.3e-35 S Phage derived protein Gp49-like (DUF891)
BPHMMAGG_00439 8.5e-20 K Helix-turn-helix XRE-family like proteins
BPHMMAGG_00440 8.8e-164 I alpha/beta hydrolase fold
BPHMMAGG_00441 1e-111 frnE Q DSBA-like thioredoxin domain
BPHMMAGG_00442 1.7e-105 L Helix-turn-helix domain
BPHMMAGG_00443 1.1e-72 S Membrane
BPHMMAGG_00444 2.3e-156 L Transposase
BPHMMAGG_00445 4.1e-19
BPHMMAGG_00446 3.5e-183 ampC V Beta-lactamase
BPHMMAGG_00447 3.1e-218 arcA 3.5.3.6 E Arginine
BPHMMAGG_00448 2.7e-79 argR K Regulates arginine biosynthesis genes
BPHMMAGG_00449 1.4e-259 E Arginine ornithine antiporter
BPHMMAGG_00450 1.4e-222 arcD U Amino acid permease
BPHMMAGG_00451 9.2e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
BPHMMAGG_00452 6.4e-262 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
BPHMMAGG_00453 6e-108 tdk 2.7.1.21 F thymidine kinase
BPHMMAGG_00454 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BPHMMAGG_00455 6.6e-167 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
BPHMMAGG_00456 4e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
BPHMMAGG_00457 9.5e-228 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BPHMMAGG_00458 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BPHMMAGG_00459 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BPHMMAGG_00460 2.2e-191 yibE S overlaps another CDS with the same product name
BPHMMAGG_00461 2.6e-130 yibF S overlaps another CDS with the same product name
BPHMMAGG_00462 5.9e-233 pyrP F Permease
BPHMMAGG_00463 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
BPHMMAGG_00464 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BPHMMAGG_00465 9.7e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BPHMMAGG_00466 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BPHMMAGG_00467 1.5e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BPHMMAGG_00468 7.4e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BPHMMAGG_00469 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BPHMMAGG_00470 1e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
BPHMMAGG_00471 1.3e-33 ywzB S Protein of unknown function (DUF1146)
BPHMMAGG_00472 3.4e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BPHMMAGG_00473 1.9e-178 mbl D Cell shape determining protein MreB Mrl
BPHMMAGG_00474 1.3e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
BPHMMAGG_00475 1e-31 S Protein of unknown function (DUF2969)
BPHMMAGG_00476 1.1e-220 rodA D Belongs to the SEDS family
BPHMMAGG_00477 1.4e-47 gcvH E glycine cleavage
BPHMMAGG_00478 3.4e-216 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
BPHMMAGG_00479 1.5e-147 2.3.1.19 K Helix-turn-helix XRE-family like proteins
BPHMMAGG_00480 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
BPHMMAGG_00481 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
BPHMMAGG_00482 4.3e-172 malR K Transcriptional regulator, LacI family
BPHMMAGG_00483 5.7e-214 phbA 2.3.1.9 I Belongs to the thiolase family
BPHMMAGG_00484 1.1e-256 malT G Major Facilitator
BPHMMAGG_00485 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
BPHMMAGG_00486 5.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
BPHMMAGG_00487 1e-71
BPHMMAGG_00488 3.7e-87 2.7.6.5 T Region found in RelA / SpoT proteins
BPHMMAGG_00489 2.1e-117 K response regulator
BPHMMAGG_00490 3.1e-226 sptS 2.7.13.3 T Histidine kinase
BPHMMAGG_00491 8.8e-215 yfeO P Voltage gated chloride channel
BPHMMAGG_00492 1.6e-257 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
BPHMMAGG_00493 6.6e-136 puuD S peptidase C26
BPHMMAGG_00494 5.9e-168 yvgN C Aldo keto reductase
BPHMMAGG_00495 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
BPHMMAGG_00496 3e-87 hmpT S ECF-type riboflavin transporter, S component
BPHMMAGG_00497 1.7e-262 nox C NADH oxidase
BPHMMAGG_00498 9.9e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
BPHMMAGG_00499 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BPHMMAGG_00500 6.9e-83
BPHMMAGG_00501 1.4e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BPHMMAGG_00503 1.1e-13 steT_1 E amino acid
BPHMMAGG_00504 2.1e-12 K Transcriptional regulator, TetR family
BPHMMAGG_00505 3.4e-74 K Transcriptional regulator, TetR family
BPHMMAGG_00506 8.3e-72
BPHMMAGG_00507 1.5e-267 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
BPHMMAGG_00508 1.4e-270 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
BPHMMAGG_00509 1.1e-271 M protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
BPHMMAGG_00510 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
BPHMMAGG_00511 8.3e-265 G Major Facilitator
BPHMMAGG_00512 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
BPHMMAGG_00513 4.8e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
BPHMMAGG_00514 1.8e-259 G Major Facilitator
BPHMMAGG_00515 1.1e-173 K Transcriptional regulator, LacI family
BPHMMAGG_00516 5.9e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BPHMMAGG_00518 2.1e-100 nqr 1.5.1.36 S reductase
BPHMMAGG_00519 5.9e-201 XK27_09615 S reductase
BPHMMAGG_00520 1.7e-176 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
BPHMMAGG_00521 3e-27 L PFAM transposase IS200-family protein
BPHMMAGG_00522 6.3e-37 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
BPHMMAGG_00523 1.2e-249 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BPHMMAGG_00524 2.2e-263 glnP P ABC transporter
BPHMMAGG_00525 1.9e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
BPHMMAGG_00526 1.6e-220 cycA E Amino acid permease
BPHMMAGG_00527 1.3e-218 nupG F Nucleoside transporter
BPHMMAGG_00528 6.6e-170 rihC 3.2.2.1 F Nucleoside
BPHMMAGG_00529 7.7e-163 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
BPHMMAGG_00530 3.7e-123 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
BPHMMAGG_00531 1.5e-143 noc K Belongs to the ParB family
BPHMMAGG_00532 3.6e-140 soj D Sporulation initiation inhibitor
BPHMMAGG_00533 5e-154 spo0J K Belongs to the ParB family
BPHMMAGG_00534 1.2e-31 yyzM S Bacterial protein of unknown function (DUF951)
BPHMMAGG_00535 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
BPHMMAGG_00536 3.1e-136 XK27_01040 S Protein of unknown function (DUF1129)
BPHMMAGG_00537 3.4e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BPHMMAGG_00538 4.5e-235 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
BPHMMAGG_00539 3.2e-234 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
BPHMMAGG_00540 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
BPHMMAGG_00541 1.4e-170 deoR K sugar-binding domain protein
BPHMMAGG_00542 1.6e-208 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
BPHMMAGG_00543 3.8e-125 K response regulator
BPHMMAGG_00544 2.4e-201 hpk31 2.7.13.3 T Histidine kinase
BPHMMAGG_00545 2.3e-138 azlC E AzlC protein
BPHMMAGG_00546 1.6e-52 azlD S branched-chain amino acid
BPHMMAGG_00547 1.1e-24 K LysR substrate binding domain
BPHMMAGG_00548 8.6e-98 K LysR substrate binding domain
BPHMMAGG_00549 5e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
BPHMMAGG_00550 8.1e-246 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
BPHMMAGG_00551 3.6e-171 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
BPHMMAGG_00552 6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
BPHMMAGG_00553 9.6e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BPHMMAGG_00554 3.7e-114 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
BPHMMAGG_00555 7.9e-96 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BPHMMAGG_00556 1.8e-228 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
BPHMMAGG_00557 6.6e-174 K AI-2E family transporter
BPHMMAGG_00558 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
BPHMMAGG_00559 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
BPHMMAGG_00560 2.5e-127 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
BPHMMAGG_00561 2.7e-24 K helix_turn_helix, arabinose operon control protein
BPHMMAGG_00562 3.4e-187 thrC 4.2.3.1 E Threonine synthase
BPHMMAGG_00563 5.8e-172 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
BPHMMAGG_00564 1.4e-100 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
BPHMMAGG_00565 2.1e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BPHMMAGG_00566 3.9e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BPHMMAGG_00567 1.3e-251 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BPHMMAGG_00568 2.2e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
BPHMMAGG_00569 4.1e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BPHMMAGG_00570 3.1e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BPHMMAGG_00571 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BPHMMAGG_00572 2e-277 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BPHMMAGG_00573 1.4e-195 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
BPHMMAGG_00574 3.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BPHMMAGG_00575 1e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
BPHMMAGG_00576 1.8e-242 purD 6.3.4.13 F Belongs to the GARS family
BPHMMAGG_00577 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BPHMMAGG_00578 1.8e-166
BPHMMAGG_00579 3.5e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BPHMMAGG_00580 3.4e-55 ansA 3.5.1.1 EJ Asparaginase
BPHMMAGG_00581 4.7e-24 S Phage terminase, small subunit
BPHMMAGG_00582 3.3e-43 yjbH Q Thioredoxin
BPHMMAGG_00583 6.7e-177 S FRG
BPHMMAGG_00584 1.8e-211 yfnA E Amino Acid
BPHMMAGG_00585 1.1e-87 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BPHMMAGG_00586 1.9e-54 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BPHMMAGG_00587 5.3e-64 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
BPHMMAGG_00588 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BPHMMAGG_00589 1.4e-297 mco Q Multicopper oxidase
BPHMMAGG_00590 1.7e-127 L PFAM Integrase catalytic region
BPHMMAGG_00591 4.3e-124 L Belongs to the 'phage' integrase family
BPHMMAGG_00592 4.2e-13
BPHMMAGG_00593 8.8e-58
BPHMMAGG_00597 1e-66 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
BPHMMAGG_00598 4.1e-37
BPHMMAGG_00599 0.0 L Type III restriction enzyme, res subunit
BPHMMAGG_00600 4.7e-131 L Belongs to the 'phage' integrase family
BPHMMAGG_00601 2.5e-19
BPHMMAGG_00602 2.7e-68 S Plasmid replication protein
BPHMMAGG_00604 1.6e-32 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
BPHMMAGG_00607 3.2e-81 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
BPHMMAGG_00608 2.4e-254 hsdM 2.1.1.72 V type I restriction-modification system
BPHMMAGG_00609 1.1e-309 hsdR 3.1.21.3 L Type I restriction enzyme R protein N terminus (HSDR_N)
BPHMMAGG_00611 2.8e-82 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
BPHMMAGG_00612 0.0 2.7.7.6 M Peptidase family M23
BPHMMAGG_00613 6.5e-119 rfbP 2.7.8.6 M Bacterial sugar transferase
BPHMMAGG_00614 1e-170 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
BPHMMAGG_00615 1.9e-146 cps1D M Domain of unknown function (DUF4422)
BPHMMAGG_00616 3.2e-136 recX 2.4.1.337 GT4 S Regulatory protein RecX
BPHMMAGG_00617 4.9e-31
BPHMMAGG_00618 6.6e-34 S Protein of unknown function (DUF2922)
BPHMMAGG_00619 4.4e-142 yihY S Belongs to the UPF0761 family
BPHMMAGG_00620 9e-281 yjeM E Amino Acid
BPHMMAGG_00621 3.7e-70 E Arginine ornithine antiporter
BPHMMAGG_00622 2.4e-159 E Arginine ornithine antiporter
BPHMMAGG_00623 1.6e-221 arcT 2.6.1.1 E Aminotransferase
BPHMMAGG_00624 1.3e-167 map 3.4.11.18 E Methionine Aminopeptidase
BPHMMAGG_00625 1.4e-78 fld C Flavodoxin
BPHMMAGG_00626 1.3e-67 gtcA S Teichoic acid glycosylation protein
BPHMMAGG_00627 1.4e-14
BPHMMAGG_00628 3.8e-33
BPHMMAGG_00629 9e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
BPHMMAGG_00631 2.5e-231 yfmL L DEAD DEAH box helicase
BPHMMAGG_00632 1.3e-190 mocA S Oxidoreductase
BPHMMAGG_00633 9.1e-62 S Domain of unknown function (DUF4828)
BPHMMAGG_00634 4e-104 yvdD 3.2.2.10 S Belongs to the LOG family
BPHMMAGG_00635 3.5e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
BPHMMAGG_00636 3.7e-298 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
BPHMMAGG_00637 3.3e-194 S Protein of unknown function (DUF3114)
BPHMMAGG_00638 4.6e-79 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
BPHMMAGG_00639 4.3e-116 ybhL S Belongs to the BI1 family
BPHMMAGG_00640 4.9e-64 yhjX P Major Facilitator Superfamily
BPHMMAGG_00641 1.1e-14
BPHMMAGG_00642 8.8e-95 K Acetyltransferase (GNAT) family
BPHMMAGG_00643 4.6e-76 K LytTr DNA-binding domain
BPHMMAGG_00644 1.8e-67 S Protein of unknown function (DUF3021)
BPHMMAGG_00645 6.1e-155 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
BPHMMAGG_00646 3.1e-75 ogt 2.1.1.63 L Methyltransferase
BPHMMAGG_00647 1.2e-120 pnb C nitroreductase
BPHMMAGG_00648 7.4e-92
BPHMMAGG_00649 5.6e-83 yvbK 3.1.3.25 K GNAT family
BPHMMAGG_00650 6.6e-251 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
BPHMMAGG_00651 1.7e-202 amtB P ammonium transporter
BPHMMAGG_00652 1e-146 M transferase activity, transferring glycosyl groups
BPHMMAGG_00653 1.6e-16 nss M transferase activity, transferring glycosyl groups
BPHMMAGG_00654 7.9e-54 nss M transferase activity, transferring glycosyl groups
BPHMMAGG_00655 1.7e-43 M Glycosyltransferase like family 2
BPHMMAGG_00656 1.9e-158 M family 8
BPHMMAGG_00657 1.2e-188 nss M transferase activity, transferring glycosyl groups
BPHMMAGG_00658 5.9e-58 M family 8
BPHMMAGG_00659 3.7e-157 M Glycosyltransferase like family 2
BPHMMAGG_00660 4.6e-155 M Glycosyl transferase family 8
BPHMMAGG_00661 8.7e-70 M Glycosyltransferase like family 2
BPHMMAGG_00662 4.4e-27 M Glycosyltransferase like family 2
BPHMMAGG_00663 1.6e-21 2.7.8.12 GT2 M Glycosyltransferase like family 2
BPHMMAGG_00664 1.3e-28 2.7.8.12 GT2 M Glycosyltransferase like family 2
BPHMMAGG_00665 1.4e-63 2.7.8.12 GT2 M Glycosyltransferase like family 2
BPHMMAGG_00666 3.6e-169 arbx M family 8
BPHMMAGG_00667 1e-63 arbx M family 8
BPHMMAGG_00668 2.7e-96 M Glycosyltransferase like family 2
BPHMMAGG_00669 1.1e-220 secY2 U SecY translocase
BPHMMAGG_00670 2e-275 asp1 S Accessory Sec system protein Asp1
BPHMMAGG_00671 1.5e-302 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
BPHMMAGG_00672 2.6e-17 asp3 S Accessory Sec secretory system ASP3
BPHMMAGG_00673 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
BPHMMAGG_00675 3.7e-282 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
BPHMMAGG_00676 4.2e-261 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
BPHMMAGG_00677 7.8e-22 L Phage integrase, N-terminal SAM-like domain
BPHMMAGG_00678 1.3e-224 oxlT P Major Facilitator Superfamily
BPHMMAGG_00679 1.7e-159 spoU 2.1.1.185 J Methyltransferase
BPHMMAGG_00680 2.8e-97 ywlG S Belongs to the UPF0340 family
BPHMMAGG_00681 4.6e-49 S ParE toxin of type II toxin-antitoxin system, parDE
BPHMMAGG_00682 1e-37 D Antitoxin component of a toxin-antitoxin (TA) module
BPHMMAGG_00683 3.3e-260 L Transposase
BPHMMAGG_00684 9.5e-33 glsA 3.5.1.2 E Belongs to the glutaminase family
BPHMMAGG_00685 6.9e-110 glsA 3.5.1.2 E Belongs to the glutaminase family
BPHMMAGG_00686 1.5e-252 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BPHMMAGG_00687 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
BPHMMAGG_00688 6.7e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
BPHMMAGG_00689 8.5e-295 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
BPHMMAGG_00691 3.2e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
BPHMMAGG_00692 1.1e-209 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BPHMMAGG_00693 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
BPHMMAGG_00694 3.1e-251 U Belongs to the purine-cytosine permease (2.A.39) family
BPHMMAGG_00695 2.3e-242 codA 3.5.4.1 F cytosine deaminase
BPHMMAGG_00696 6.4e-145 tesE Q hydratase
BPHMMAGG_00697 1.1e-113 S (CBS) domain
BPHMMAGG_00698 1.3e-102 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
BPHMMAGG_00699 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BPHMMAGG_00700 2.1e-39 yabO J S4 domain protein
BPHMMAGG_00701 1.6e-55 divIC D Septum formation initiator
BPHMMAGG_00702 9.8e-67 yabR J RNA binding
BPHMMAGG_00703 2.7e-250 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
BPHMMAGG_00704 1.3e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
BPHMMAGG_00705 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BPHMMAGG_00706 1.1e-169 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BPHMMAGG_00707 4.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BPHMMAGG_00708 1.6e-293 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
BPHMMAGG_00709 3e-85
BPHMMAGG_00710 3e-29
BPHMMAGG_00711 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BPHMMAGG_00713 4.3e-87 yxiO S Vacuole effluxer Atg22 like
BPHMMAGG_00714 2e-93 yxiO S Vacuole effluxer Atg22 like
BPHMMAGG_00715 5.5e-214 npp S type I phosphodiesterase nucleotide pyrophosphatase
BPHMMAGG_00716 7.9e-32 npp S type I phosphodiesterase nucleotide pyrophosphatase
BPHMMAGG_00717 2.3e-238 E amino acid
BPHMMAGG_00718 6.7e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BPHMMAGG_00720 3.3e-219 yxjG_1 E methionine synthase, vitamin-B12 independent
BPHMMAGG_00721 6.5e-14 S Cytochrome B5
BPHMMAGG_00722 1.5e-74 elaA S Gnat family
BPHMMAGG_00723 1.2e-120 GM NmrA-like family
BPHMMAGG_00724 1.8e-50 hxlR K Transcriptional regulator, HxlR family
BPHMMAGG_00725 4.1e-107 XK27_02070 S Nitroreductase family
BPHMMAGG_00726 4.4e-82 K Transcriptional regulator, HxlR family
BPHMMAGG_00727 4.4e-231
BPHMMAGG_00728 6.5e-210 EGP Major facilitator Superfamily
BPHMMAGG_00729 8.8e-256 pepC 3.4.22.40 E aminopeptidase
BPHMMAGG_00730 2.6e-112 ylbE GM NAD dependent epimerase dehydratase family protein
BPHMMAGG_00731 0.0 pepN 3.4.11.2 E aminopeptidase
BPHMMAGG_00732 1.9e-48 K Transcriptional regulator
BPHMMAGG_00733 2.3e-24 folT S ECF transporter, substrate-specific component
BPHMMAGG_00734 1.9e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
BPHMMAGG_00735 5.1e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
BPHMMAGG_00736 3.7e-26 L PFAM Integrase catalytic region
BPHMMAGG_00737 0.0 FbpA K Fibronectin-binding protein
BPHMMAGG_00738 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
BPHMMAGG_00739 1.1e-206 carA 6.3.5.5 F Belongs to the CarA family
BPHMMAGG_00740 4.2e-172 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
BPHMMAGG_00741 9.5e-69 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BPHMMAGG_00742 5.6e-65 esbA S Family of unknown function (DUF5322)
BPHMMAGG_00743 4.4e-70 rnhA 3.1.26.4 L Ribonuclease HI
BPHMMAGG_00744 4.3e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
BPHMMAGG_00745 8e-82 F Belongs to the NrdI family
BPHMMAGG_00746 1.2e-42 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
BPHMMAGG_00747 3.2e-101 ypsA S Belongs to the UPF0398 family
BPHMMAGG_00748 5.8e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
BPHMMAGG_00749 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
BPHMMAGG_00750 1.3e-160 EG EamA-like transporter family
BPHMMAGG_00751 8.1e-123 dnaD L DnaD domain protein
BPHMMAGG_00752 9.9e-86 ypmB S Protein conserved in bacteria
BPHMMAGG_00753 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
BPHMMAGG_00754 8.2e-171 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
BPHMMAGG_00755 7.4e-167 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
BPHMMAGG_00756 3e-212 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
BPHMMAGG_00757 3.2e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
BPHMMAGG_00758 2.5e-86 S Protein of unknown function (DUF1440)
BPHMMAGG_00759 2.9e-120 L Transposase
BPHMMAGG_00760 5e-157 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
BPHMMAGG_00761 7e-75 S Protein of unknown function (DUF3278)
BPHMMAGG_00763 2.3e-73 M PFAM NLP P60 protein
BPHMMAGG_00764 2.2e-182 ABC-SBP S ABC transporter
BPHMMAGG_00765 3.3e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
BPHMMAGG_00766 4.8e-137 XK27_08845 S ABC transporter, ATP-binding protein
BPHMMAGG_00767 2.6e-95 P Cadmium resistance transporter
BPHMMAGG_00768 5.2e-56 K Transcriptional regulator, ArsR family
BPHMMAGG_00769 9.2e-237 mepA V MATE efflux family protein
BPHMMAGG_00770 1.1e-55 trxA O Belongs to the thioredoxin family
BPHMMAGG_00771 6.6e-131 terC P membrane
BPHMMAGG_00772 9.1e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
BPHMMAGG_00773 2.8e-168 corA P CorA-like Mg2+ transporter protein
BPHMMAGG_00774 6.2e-279 pipD E Dipeptidase
BPHMMAGG_00775 1.8e-237 pbuX F xanthine permease
BPHMMAGG_00776 2.7e-250 nhaC C Na H antiporter NhaC
BPHMMAGG_00777 2.5e-184 S C4-dicarboxylate anaerobic carrier
BPHMMAGG_00778 6.7e-67 S C4-dicarboxylate anaerobic carrier
BPHMMAGG_00779 1.9e-45 IQ Dehydrogenase reductase
BPHMMAGG_00781 5.1e-35 K Bacterial transcriptional regulator
BPHMMAGG_00782 1.8e-124 pgm3 3.1.3.73 G phosphoglycerate mutase family
BPHMMAGG_00783 1.2e-39
BPHMMAGG_00784 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
BPHMMAGG_00785 9.3e-206 gldA 1.1.1.6 C dehydrogenase
BPHMMAGG_00786 1.6e-89 O Bacterial dnaA protein
BPHMMAGG_00787 3e-218 L Integrase core domain
BPHMMAGG_00789 5.5e-14 L MULE transposase domain
BPHMMAGG_00790 1e-145 L Transposase
BPHMMAGG_00791 3.2e-96 epsB M biosynthesis protein
BPHMMAGG_00792 1.7e-107 ywqD 2.7.10.1 D Capsular exopolysaccharide family
BPHMMAGG_00793 4e-49 pglC M Bacterial sugar transferase
BPHMMAGG_00794 4.8e-88 GT4 G Glycosyl transferase 4-like
BPHMMAGG_00795 6.1e-68 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
BPHMMAGG_00796 4.9e-43 M Glycosyl transferase, family 2 glycosyl transferase family 8
BPHMMAGG_00798 1.3e-72 cps2I S Psort location CytoplasmicMembrane, score
BPHMMAGG_00799 5.1e-35 M Glycosyltransferase sugar-binding region containing DXD motif
BPHMMAGG_00800 4.7e-28 epsJ1 2.7.8.12 M Glycosyltransferase, group 2 family protein
BPHMMAGG_00801 7.2e-29 S COG0463 Glycosyltransferases involved in cell wall biogenesis
BPHMMAGG_00802 6.5e-50 S Glycosyltransferase, group 2 family protein
BPHMMAGG_00804 1.2e-29 S Acyltransferase family
BPHMMAGG_00805 0.0 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
BPHMMAGG_00806 3.4e-169 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
BPHMMAGG_00807 2.7e-39
BPHMMAGG_00808 0.0 ydaO E amino acid
BPHMMAGG_00809 4.5e-302 ybeC E amino acid
BPHMMAGG_00810 5.3e-81 S Aminoacyl-tRNA editing domain
BPHMMAGG_00811 5.5e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
BPHMMAGG_00812 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BPHMMAGG_00814 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BPHMMAGG_00815 2.7e-311 uup S ABC transporter, ATP-binding protein
BPHMMAGG_00816 6.2e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BPHMMAGG_00817 1.3e-226 mtnE 2.6.1.83 E Aminotransferase
BPHMMAGG_00818 5.6e-141 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
BPHMMAGG_00819 8.4e-137 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BPHMMAGG_00820 1.2e-217 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BPHMMAGG_00821 8e-132 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BPHMMAGG_00822 2e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BPHMMAGG_00823 2.9e-99 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
BPHMMAGG_00824 9.5e-127 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
BPHMMAGG_00825 6.8e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
BPHMMAGG_00826 6.4e-171 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
BPHMMAGG_00827 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BPHMMAGG_00828 1.4e-281 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
BPHMMAGG_00829 5.6e-52
BPHMMAGG_00830 0.0 oatA I Acyltransferase
BPHMMAGG_00831 1.8e-78 K Transcriptional regulator
BPHMMAGG_00832 1.1e-147 XK27_02985 S Cof-like hydrolase
BPHMMAGG_00833 1.3e-76 lytE M Lysin motif
BPHMMAGG_00835 1.2e-134 K response regulator
BPHMMAGG_00836 2.6e-272 yclK 2.7.13.3 T Histidine kinase
BPHMMAGG_00837 4.1e-153 glcU U sugar transport
BPHMMAGG_00838 3.5e-98 lacA 2.3.1.79 S Transferase hexapeptide repeat
BPHMMAGG_00839 1.1e-261 pgi 5.3.1.9 G Belongs to the GPI family
BPHMMAGG_00840 1e-25
BPHMMAGG_00843 6.2e-31 xylB 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
BPHMMAGG_00844 1.2e-154 KT YcbB domain
BPHMMAGG_00845 7.6e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BPHMMAGG_00846 2.1e-171 arcC 2.7.2.2 E Belongs to the carbamate kinase family
BPHMMAGG_00847 3.3e-161 EG EamA-like transporter family
BPHMMAGG_00848 1.3e-102 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
BPHMMAGG_00849 1.1e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
BPHMMAGG_00850 0.0 copA 3.6.3.54 P P-type ATPase
BPHMMAGG_00851 1.2e-85
BPHMMAGG_00853 2.3e-56
BPHMMAGG_00854 3.9e-40 yjcE P Sodium proton antiporter
BPHMMAGG_00855 2.8e-95 yjcE P Sodium proton antiporter
BPHMMAGG_00857 7.4e-94
BPHMMAGG_00858 2.7e-67 yqkB S Belongs to the HesB IscA family
BPHMMAGG_00859 8.6e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
BPHMMAGG_00860 4e-78 F NUDIX domain
BPHMMAGG_00861 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
BPHMMAGG_00862 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
BPHMMAGG_00863 1.2e-104 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
BPHMMAGG_00864 1.4e-164 lacX 5.1.3.3 G Aldose 1-epimerase
BPHMMAGG_00865 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BPHMMAGG_00868 3.6e-259 V Type II restriction enzyme, methylase subunits
BPHMMAGG_00869 1.3e-10
BPHMMAGG_00870 1.4e-130 M Glycosyl hydrolases family 25
BPHMMAGG_00871 2.3e-16 hol S COG5546 Small integral membrane protein
BPHMMAGG_00873 8e-11
BPHMMAGG_00875 5.8e-16 M Prophage endopeptidase tail
BPHMMAGG_00876 1.3e-19 S Phage tail protein
BPHMMAGG_00877 2.2e-123 dnaG S EVIDENCE BY HOMOLOGY BIO14.03 Phage related functions and prophages
BPHMMAGG_00881 2.2e-18 S Protein of unknown function (DUF806)
BPHMMAGG_00882 3.7e-20 S Bacteriophage HK97-gp10, putative tail-component
BPHMMAGG_00883 3.9e-12 S Phage head-tail joining protein
BPHMMAGG_00884 1.6e-23 S Phage gp6-like head-tail connector protein
BPHMMAGG_00885 3.1e-167 S Phage capsid family
BPHMMAGG_00886 1.4e-56 S Clp protease
BPHMMAGG_00887 1.5e-153 S Phage portal protein
BPHMMAGG_00888 6.3e-255 S Phage Terminase
BPHMMAGG_00889 1.1e-33 L Phage terminase, small subunit
BPHMMAGG_00890 3.3e-57 L HNH nucleases
BPHMMAGG_00894 2.8e-51
BPHMMAGG_00896 1.2e-42 S D5 N terminal like
BPHMMAGG_00905 8.6e-74 S N-methyltransferase activity
BPHMMAGG_00907 1.9e-133 S Domain of unknown function (DUF3440)
BPHMMAGG_00909 1.5e-108 S Type III restriction enzyme, res subunit
BPHMMAGG_00911 4.6e-10 S Domain of unknown function (DUF771)
BPHMMAGG_00914 9.1e-44 L Belongs to the 'phage' integrase family
BPHMMAGG_00915 1.4e-128 dprA LU DNA protecting protein DprA
BPHMMAGG_00916 7.9e-140 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BPHMMAGG_00917 9.2e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BPHMMAGG_00918 4.4e-35 yozE S Belongs to the UPF0346 family
BPHMMAGG_00919 2.8e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
BPHMMAGG_00920 2e-166 ypmR E lipolytic protein G-D-S-L family
BPHMMAGG_00921 4.9e-151 DegV S EDD domain protein, DegV family
BPHMMAGG_00922 1.9e-110 hlyIII S protein, hemolysin III
BPHMMAGG_00923 9.6e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BPHMMAGG_00924 7.2e-191 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BPHMMAGG_00925 0.0 yfmR S ABC transporter, ATP-binding protein
BPHMMAGG_00926 4.5e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
BPHMMAGG_00927 2.6e-233 S Tetratricopeptide repeat protein
BPHMMAGG_00928 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
BPHMMAGG_00929 4.7e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
BPHMMAGG_00930 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
BPHMMAGG_00931 1.3e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
BPHMMAGG_00932 9.7e-25 M Lysin motif
BPHMMAGG_00933 2.4e-267 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
BPHMMAGG_00934 2.6e-194 ypbB 5.1.3.1 S Helix-turn-helix domain
BPHMMAGG_00935 2.1e-100 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BPHMMAGG_00936 5.9e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
BPHMMAGG_00937 1.7e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BPHMMAGG_00938 2.5e-136 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BPHMMAGG_00939 2.8e-63 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
BPHMMAGG_00940 3.8e-162 xerD D recombinase XerD
BPHMMAGG_00941 9.3e-169 cvfB S S1 domain
BPHMMAGG_00942 3.6e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
BPHMMAGG_00943 0.0 dnaE 2.7.7.7 L DNA polymerase
BPHMMAGG_00944 2e-29 S Protein of unknown function (DUF2929)
BPHMMAGG_00945 6.6e-237 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
BPHMMAGG_00946 6.5e-156 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BPHMMAGG_00947 6.2e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
BPHMMAGG_00948 2.4e-220 patA 2.6.1.1 E Aminotransferase
BPHMMAGG_00949 7.7e-208 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
BPHMMAGG_00950 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
BPHMMAGG_00951 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
BPHMMAGG_00952 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
BPHMMAGG_00953 3.8e-145 recO L Involved in DNA repair and RecF pathway recombination
BPHMMAGG_00954 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BPHMMAGG_00955 3.8e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
BPHMMAGG_00956 3.3e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BPHMMAGG_00957 2.2e-182 phoH T phosphate starvation-inducible protein PhoH
BPHMMAGG_00958 5.4e-170 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
BPHMMAGG_00959 3.8e-83 bioY S BioY family
BPHMMAGG_00960 7.8e-263 argH 4.3.2.1 E argininosuccinate lyase
BPHMMAGG_00961 1.7e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
BPHMMAGG_00962 1.4e-186 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
BPHMMAGG_00963 9.1e-14
BPHMMAGG_00964 2.6e-32 yfbR S HD containing hydrolase-like enzyme
BPHMMAGG_00965 9.8e-61 yfbR S HD containing hydrolase-like enzyme
BPHMMAGG_00966 6.9e-153 L Transposase
BPHMMAGG_00967 1.1e-67 L Transposase
BPHMMAGG_00968 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
BPHMMAGG_00969 7.2e-89 ykhA 3.1.2.20 I Thioesterase superfamily
BPHMMAGG_00970 2.9e-162 aatB ET PFAM extracellular solute-binding protein, family 3
BPHMMAGG_00971 1.8e-204 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
BPHMMAGG_00972 8.6e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
BPHMMAGG_00973 7.8e-168 lutA C Cysteine-rich domain
BPHMMAGG_00974 2.3e-292 lutB C 4Fe-4S dicluster domain
BPHMMAGG_00975 1.7e-136 yrjD S LUD domain
BPHMMAGG_00976 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
BPHMMAGG_00977 8.5e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
BPHMMAGG_00978 3.2e-155 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BPHMMAGG_00979 1.7e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BPHMMAGG_00980 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
BPHMMAGG_00981 7.7e-31 KT PspC domain protein
BPHMMAGG_00982 6.6e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BPHMMAGG_00983 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
BPHMMAGG_00984 4.5e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BPHMMAGG_00985 1.1e-93 comFC S Competence protein
BPHMMAGG_00986 9.5e-250 comFA L Helicase C-terminal domain protein
BPHMMAGG_00987 4.3e-107 yvyE 3.4.13.9 S YigZ family
BPHMMAGG_00988 5.8e-184 S Phosphotransferase system, EIIC
BPHMMAGG_00989 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BPHMMAGG_00990 3.9e-182
BPHMMAGG_00991 4.7e-63 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BPHMMAGG_00992 2.8e-70 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
BPHMMAGG_00993 1.2e-97 2.3.1.128 K acetyltransferase
BPHMMAGG_00994 5.1e-187
BPHMMAGG_00995 1.6e-15 K Transcriptional regulator, HxlR family
BPHMMAGG_00996 3.6e-131 K Transcriptional regulatory protein, C-terminal domain protein
BPHMMAGG_00997 1.3e-159 pstS P Phosphate
BPHMMAGG_00998 1.6e-152 pstC P probably responsible for the translocation of the substrate across the membrane
BPHMMAGG_00999 5.9e-155 pstA P Phosphate transport system permease protein PstA
BPHMMAGG_01000 3.1e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
BPHMMAGG_01001 6.6e-125 phoU P Plays a role in the regulation of phosphate uptake
BPHMMAGG_01002 1.2e-139
BPHMMAGG_01004 4.2e-242 ydaM M Glycosyl transferase
BPHMMAGG_01005 1.1e-106 G Glycosyl hydrolases family 8
BPHMMAGG_01006 4.4e-85 G Glycosyl hydrolases family 8
BPHMMAGG_01007 1.4e-44 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
BPHMMAGG_01008 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
BPHMMAGG_01009 7.6e-239 ktrB P Potassium uptake protein
BPHMMAGG_01010 1.4e-116 ktrA P domain protein
BPHMMAGG_01011 1.9e-79 Q Methyltransferase
BPHMMAGG_01012 8.6e-156 ytbE 1.1.1.346 S Aldo keto reductase
BPHMMAGG_01013 3.2e-124 K response regulator
BPHMMAGG_01014 2.6e-180 T PhoQ Sensor
BPHMMAGG_01015 2.7e-132 macB2 V ABC transporter, ATP-binding protein
BPHMMAGG_01016 4.3e-129 ysaB V FtsX-like permease family
BPHMMAGG_01017 9.4e-187 ysaB V FtsX-like permease family
BPHMMAGG_01018 5.9e-157 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
BPHMMAGG_01019 1.1e-167 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
BPHMMAGG_01021 3.2e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BPHMMAGG_01022 3.8e-194 EGP Major facilitator Superfamily
BPHMMAGG_01023 6e-88 ymdB S Macro domain protein
BPHMMAGG_01024 3e-99 K Helix-turn-helix XRE-family like proteins
BPHMMAGG_01025 0.0 pepO 3.4.24.71 O Peptidase family M13
BPHMMAGG_01026 1.9e-46
BPHMMAGG_01027 2.1e-230 S Putative metallopeptidase domain
BPHMMAGG_01028 9.8e-203 3.1.3.1 S associated with various cellular activities
BPHMMAGG_01029 5.2e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
BPHMMAGG_01030 5.9e-64 yeaO S Protein of unknown function, DUF488
BPHMMAGG_01032 1.5e-118 yrkL S Flavodoxin-like fold
BPHMMAGG_01033 1.5e-52
BPHMMAGG_01034 5.3e-16 S Domain of unknown function (DUF4767)
BPHMMAGG_01035 1e-27 3.6.4.12 S PD-(D/E)XK nuclease family transposase
BPHMMAGG_01036 9.1e-49
BPHMMAGG_01037 3.3e-39 ykuJ S Protein of unknown function (DUF1797)
BPHMMAGG_01038 1.1e-178 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BPHMMAGG_01039 4.5e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
BPHMMAGG_01040 2.5e-228 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
BPHMMAGG_01041 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BPHMMAGG_01042 2.7e-39 ptsH G phosphocarrier protein HPR
BPHMMAGG_01043 2.9e-27
BPHMMAGG_01044 0.0 clpE O Belongs to the ClpA ClpB family
BPHMMAGG_01045 7e-99 S Pfam:DUF3816
BPHMMAGG_01046 2e-140 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
BPHMMAGG_01047 8.4e-117
BPHMMAGG_01048 1.2e-155 V ABC transporter, ATP-binding protein
BPHMMAGG_01049 7.9e-64 gntR1 K Transcriptional regulator, GntR family
BPHMMAGG_01050 0.0 S Peptidase, M23
BPHMMAGG_01051 0.0 M NlpC/P60 family
BPHMMAGG_01052 1.8e-308 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BPHMMAGG_01053 1.1e-222 brpA K Cell envelope-like function transcriptional attenuator common domain protein
BPHMMAGG_01054 5.2e-53 ywiB S Domain of unknown function (DUF1934)
BPHMMAGG_01055 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
BPHMMAGG_01056 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
BPHMMAGG_01057 2e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BPHMMAGG_01058 4.6e-41 rpmE2 J Ribosomal protein L31
BPHMMAGG_01059 7.7e-236 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
BPHMMAGG_01060 3.1e-164 S Alpha/beta hydrolase of unknown function (DUF915)
BPHMMAGG_01061 7.3e-116 srtA 3.4.22.70 M sortase family
BPHMMAGG_01062 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
BPHMMAGG_01063 4.7e-159 3.2.1.55 GH51 G Right handed beta helix region
BPHMMAGG_01064 9.8e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
BPHMMAGG_01065 1.3e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
BPHMMAGG_01066 9.2e-121 pgm3 3.1.3.73 G Belongs to the phosphoglycerate mutase family
BPHMMAGG_01067 8e-87 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BPHMMAGG_01068 2e-92 lemA S LemA family
BPHMMAGG_01069 2e-158 htpX O Belongs to the peptidase M48B family
BPHMMAGG_01070 1.9e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
BPHMMAGG_01071 3.6e-253 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
BPHMMAGG_01072 1.7e-38 pspC KT PspC domain protein
BPHMMAGG_01073 1e-93 K Transcriptional regulator (TetR family)
BPHMMAGG_01074 2.3e-216 V domain protein
BPHMMAGG_01075 4.6e-180 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BPHMMAGG_01077 6.6e-35 S Transglycosylase associated protein
BPHMMAGG_01078 5.2e-221 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BPHMMAGG_01079 5.5e-126 3.1.3.73 G phosphoglycerate mutase
BPHMMAGG_01080 4e-116 dedA S SNARE associated Golgi protein
BPHMMAGG_01081 0.0 helD 3.6.4.12 L DNA helicase
BPHMMAGG_01082 2.8e-36 Q pyridine nucleotide-disulphide oxidoreductase
BPHMMAGG_01083 6.2e-157 EG EamA-like transporter family
BPHMMAGG_01084 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
BPHMMAGG_01085 3.7e-176 coaA 2.7.1.33 F Pantothenic acid kinase
BPHMMAGG_01086 1.7e-218 S cog cog1373
BPHMMAGG_01088 3.6e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
BPHMMAGG_01098 3.1e-93 2.3.1.128 K Acetyltransferase (GNAT) domain
BPHMMAGG_01099 6.2e-158 lmrB EGP Major facilitator Superfamily
BPHMMAGG_01100 1.1e-31 lmrB EGP Major facilitator Superfamily
BPHMMAGG_01101 6.5e-16 lmrB EGP Major facilitator Superfamily
BPHMMAGG_01102 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
BPHMMAGG_01103 7.6e-111 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BPHMMAGG_01104 3.4e-158 sufD O Uncharacterized protein family (UPF0051)
BPHMMAGG_01105 2e-42 lytE M LysM domain protein
BPHMMAGG_01106 0.0 oppD EP Psort location Cytoplasmic, score
BPHMMAGG_01107 7.3e-84 lytE M LysM domain protein
BPHMMAGG_01108 3.9e-147 xth 3.1.11.2 L exodeoxyribonuclease III
BPHMMAGG_01109 3.6e-235 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
BPHMMAGG_01110 5.3e-237 preA 1.3.1.1 C 4Fe-4S dicluster domain
BPHMMAGG_01111 5.3e-153 yeaE S Aldo keto
BPHMMAGG_01112 2e-76 hsp O Belongs to the small heat shock protein (HSP20) family
BPHMMAGG_01113 1.8e-284 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
BPHMMAGG_01114 2.2e-78 S Psort location Cytoplasmic, score
BPHMMAGG_01115 2.2e-85 S Short repeat of unknown function (DUF308)
BPHMMAGG_01124 4.3e-130 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
BPHMMAGG_01125 9.2e-136 accA 2.1.3.15, 6.4.1.2 I alpha subunit
BPHMMAGG_01126 8.4e-143 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BPHMMAGG_01127 1.6e-255 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
BPHMMAGG_01128 8.6e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
BPHMMAGG_01129 2e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
BPHMMAGG_01130 4.1e-223 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
BPHMMAGG_01131 3.4e-124 IQ reductase
BPHMMAGG_01132 2.9e-152 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
BPHMMAGG_01133 1.4e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
BPHMMAGG_01134 7.9e-169 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BPHMMAGG_01135 1.2e-76 marR K Transcriptional regulator, MarR family
BPHMMAGG_01136 8e-70 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
BPHMMAGG_01138 1.3e-201 xerS L Belongs to the 'phage' integrase family
BPHMMAGG_01139 5.8e-10 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
BPHMMAGG_01140 6.7e-164 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
BPHMMAGG_01141 1.6e-53 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
BPHMMAGG_01142 3e-156 rssA S Phospholipase, patatin family
BPHMMAGG_01143 9.4e-118 L Integrase
BPHMMAGG_01144 4.2e-153 EG EamA-like transporter family
BPHMMAGG_01145 3e-38 L Helix-turn-helix domain
BPHMMAGG_01146 6.5e-39 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
BPHMMAGG_01147 2.4e-56 K transcriptional regulator PadR family
BPHMMAGG_01148 1.2e-82 XK27_06920 S Protein of unknown function (DUF1700)
BPHMMAGG_01149 5.4e-133 S Putative adhesin
BPHMMAGG_01150 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
BPHMMAGG_01151 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BPHMMAGG_01152 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BPHMMAGG_01153 3.4e-35 nrdH O Glutaredoxin
BPHMMAGG_01154 1e-87 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
BPHMMAGG_01155 6.2e-292 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BPHMMAGG_01156 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BPHMMAGG_01157 6.3e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BPHMMAGG_01158 2.8e-38 S Protein of unknown function (DUF2508)
BPHMMAGG_01159 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BPHMMAGG_01160 2.9e-51 yaaQ S Cyclic-di-AMP receptor
BPHMMAGG_01161 1.4e-181 holB 2.7.7.7 L DNA polymerase III
BPHMMAGG_01162 3.1e-43 yabA L Involved in initiation control of chromosome replication
BPHMMAGG_01163 6.4e-154 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BPHMMAGG_01164 1.4e-133 fat 3.1.2.21 I Acyl-ACP thioesterase
BPHMMAGG_01165 1.4e-37 T EAL domain
BPHMMAGG_01166 7.2e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
BPHMMAGG_01167 5.5e-59 yneR
BPHMMAGG_01168 4.7e-101 qorB 1.6.5.2 GM NmrA-like family
BPHMMAGG_01169 7.4e-115 akr5f 1.1.1.346 S reductase
BPHMMAGG_01170 7.6e-147 K Transcriptional regulator
BPHMMAGG_01171 1.8e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
BPHMMAGG_01172 2.4e-160 ypuA S Protein of unknown function (DUF1002)
BPHMMAGG_01173 6.6e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
BPHMMAGG_01174 1.5e-152 tesE Q hydratase
BPHMMAGG_01175 2.5e-100 S Alpha beta hydrolase
BPHMMAGG_01176 4.7e-13 S Alpha beta hydrolase
BPHMMAGG_01178 3.8e-68 lacA S transferase hexapeptide repeat
BPHMMAGG_01179 4.7e-17 P nitric oxide dioxygenase activity
BPHMMAGG_01180 5.5e-90 S Peptidase propeptide and YPEB domain
BPHMMAGG_01181 3.2e-213 T GHKL domain
BPHMMAGG_01182 5.6e-110 T Transcriptional regulatory protein, C terminal
BPHMMAGG_01183 5.5e-228 L COG3547 Transposase and inactivated derivatives
BPHMMAGG_01184 7e-19 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
BPHMMAGG_01186 6.9e-147 holA 2.7.7.7 L DNA polymerase III delta subunit
BPHMMAGG_01187 0.0 comEC S Competence protein ComEC
BPHMMAGG_01188 3.1e-89 comEB 3.5.4.12 F ComE operon protein 2
BPHMMAGG_01189 5.8e-80 comEA L Competence protein ComEA
BPHMMAGG_01190 2.1e-196 ylbL T Belongs to the peptidase S16 family
BPHMMAGG_01191 1.5e-89 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BPHMMAGG_01192 2.1e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
BPHMMAGG_01193 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
BPHMMAGG_01194 3.8e-221 ftsW D Belongs to the SEDS family
BPHMMAGG_01195 0.0 typA T GTP-binding protein TypA
BPHMMAGG_01196 3.1e-136 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
BPHMMAGG_01197 6.9e-44 yktA S Belongs to the UPF0223 family
BPHMMAGG_01198 7e-275 lpdA 1.8.1.4 C Dehydrogenase
BPHMMAGG_01199 5.8e-223 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
BPHMMAGG_01200 2.4e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
BPHMMAGG_01201 2.8e-207 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
BPHMMAGG_01202 1.4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
BPHMMAGG_01203 2.6e-77
BPHMMAGG_01204 9.8e-32 ykzG S Belongs to the UPF0356 family
BPHMMAGG_01205 6.7e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
BPHMMAGG_01206 5.7e-29
BPHMMAGG_01207 3.8e-130 mltD CBM50 M NlpC P60 family protein
BPHMMAGG_01209 2.2e-57
BPHMMAGG_01210 9.5e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
BPHMMAGG_01211 1.1e-218 EG GntP family permease
BPHMMAGG_01212 2.6e-48 KT Putative sugar diacid recognition
BPHMMAGG_01213 9.9e-24 KT Putative sugar diacid recognition
BPHMMAGG_01214 2.6e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BPHMMAGG_01215 1.2e-214 patA 2.6.1.1 E Aminotransferase
BPHMMAGG_01216 8e-140 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
BPHMMAGG_01217 6.5e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BPHMMAGG_01218 1e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
BPHMMAGG_01219 1.3e-72 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
BPHMMAGG_01220 2.6e-244 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
BPHMMAGG_01221 2.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
BPHMMAGG_01222 2.7e-180 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BPHMMAGG_01223 3.1e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BPHMMAGG_01224 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
BPHMMAGG_01225 3.2e-116 S Repeat protein
BPHMMAGG_01226 2.9e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
BPHMMAGG_01227 7.6e-224 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
BPHMMAGG_01228 7.5e-58 XK27_04120 S Putative amino acid metabolism
BPHMMAGG_01229 4.6e-216 iscS 2.8.1.7 E Aminotransferase class V
BPHMMAGG_01230 4.7e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BPHMMAGG_01232 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
BPHMMAGG_01233 4.2e-32 cspA K Cold shock protein
BPHMMAGG_01234 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BPHMMAGG_01235 3e-35 divIVA D DivIVA domain protein
BPHMMAGG_01236 2.2e-145 ylmH S S4 domain protein
BPHMMAGG_01237 3.2e-40 yggT S YGGT family
BPHMMAGG_01238 2.1e-70 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
BPHMMAGG_01239 3.5e-222 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BPHMMAGG_01240 2.5e-253 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
BPHMMAGG_01241 6.1e-141 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
BPHMMAGG_01242 4.7e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BPHMMAGG_01243 1.5e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BPHMMAGG_01244 4.4e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BPHMMAGG_01245 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
BPHMMAGG_01246 2.2e-55 ftsL D Cell division protein FtsL
BPHMMAGG_01247 1.3e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
BPHMMAGG_01248 3.1e-77 mraZ K Belongs to the MraZ family
BPHMMAGG_01249 1.7e-57
BPHMMAGG_01250 1.2e-10 S Protein of unknown function (DUF4044)
BPHMMAGG_01251 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
BPHMMAGG_01252 2.3e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
BPHMMAGG_01253 2.2e-159 rrmA 2.1.1.187 H Methyltransferase
BPHMMAGG_01254 6.6e-182 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
BPHMMAGG_01255 8.9e-287 mntH P H( )-stimulated, divalent metal cation uptake system
BPHMMAGG_01256 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
BPHMMAGG_01257 3.7e-85 ygfC K transcriptional regulator (TetR family)
BPHMMAGG_01258 3.3e-168 hrtB V ABC transporter permease
BPHMMAGG_01259 1.3e-117 devA 3.6.3.25 V ABC transporter, ATP-binding protein
BPHMMAGG_01260 0.0 yhcA V ABC transporter, ATP-binding protein
BPHMMAGG_01261 2.5e-36
BPHMMAGG_01262 6e-32 czrA K Transcriptional regulator, ArsR family
BPHMMAGG_01263 4.2e-234 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
BPHMMAGG_01264 1.8e-173 scrR K Transcriptional regulator, LacI family
BPHMMAGG_01265 3.9e-24
BPHMMAGG_01266 5.3e-102
BPHMMAGG_01267 2.8e-216 yttB EGP Major facilitator Superfamily
BPHMMAGG_01268 7.5e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
BPHMMAGG_01269 1.6e-85
BPHMMAGG_01270 1.5e-107 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
BPHMMAGG_01271 5.5e-134 G Peptidase_C39 like family
BPHMMAGG_01272 6.1e-25
BPHMMAGG_01273 1.4e-217 glf 5.4.99.9 M UDP-galactopyranose mutase
BPHMMAGG_01274 3.8e-244 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
BPHMMAGG_01275 3e-69 cps3F
BPHMMAGG_01276 4.9e-47 M biosynthesis protein
BPHMMAGG_01277 1.7e-139 rgpB GT2 M Glycosyltransferase, group 2 family protein
BPHMMAGG_01278 6.8e-123 M Domain of unknown function (DUF4422)
BPHMMAGG_01279 2.4e-139 S Glycosyltransferase like family
BPHMMAGG_01280 2.8e-23
BPHMMAGG_01281 2e-90 S Bacterial membrane protein, YfhO
BPHMMAGG_01282 2.2e-32
BPHMMAGG_01283 2.1e-62 M Dolichyl-phosphate-mannose-protein mannosyltransferase
BPHMMAGG_01284 1.8e-12 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BPHMMAGG_01285 2e-20 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BPHMMAGG_01286 3.5e-274 pipD E Dipeptidase
BPHMMAGG_01287 1.8e-198 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
BPHMMAGG_01289 8e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
BPHMMAGG_01290 7.5e-58
BPHMMAGG_01291 6.3e-179 prmA J Ribosomal protein L11 methyltransferase
BPHMMAGG_01292 1.1e-127 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
BPHMMAGG_01293 9.4e-50
BPHMMAGG_01294 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BPHMMAGG_01295 6e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
BPHMMAGG_01296 9.3e-166 yniA G Phosphotransferase enzyme family
BPHMMAGG_01297 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
BPHMMAGG_01298 3.8e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
BPHMMAGG_01299 1.1e-262 glnPH2 P ABC transporter permease
BPHMMAGG_01300 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
BPHMMAGG_01301 3.8e-70 yqeY S YqeY-like protein
BPHMMAGG_01302 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
BPHMMAGG_01303 7.9e-35 copZ C Heavy-metal-associated domain
BPHMMAGG_01304 2.7e-94 dps P Belongs to the Dps family
BPHMMAGG_01305 5.2e-113 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
BPHMMAGG_01306 1.7e-16 ung2 3.2.2.27 L Uracil-DNA glycosylase
BPHMMAGG_01307 7.8e-66 ung2 3.2.2.27 L Uracil-DNA glycosylase
BPHMMAGG_01308 3.6e-62 5.1.1.13 M Asp/Glu/Hydantoin racemase
BPHMMAGG_01309 7.5e-22 5.1.1.13 M Asp/Glu/Hydantoin racemase
BPHMMAGG_01310 5.4e-148 L Recombinase
BPHMMAGG_01311 1e-217 L Recombinase zinc beta ribbon domain
BPHMMAGG_01312 9.7e-20
BPHMMAGG_01313 5.4e-55 S Bacteriophage holin family
BPHMMAGG_01314 6.5e-55 S Phage head-tail joining protein
BPHMMAGG_01315 4.6e-39 S Phage gp6-like head-tail connector protein
BPHMMAGG_01316 8.8e-172 S Phage capsid family
BPHMMAGG_01317 1.2e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BPHMMAGG_01318 1.1e-127 3.6.1.13, 3.6.1.55 F NUDIX domain
BPHMMAGG_01319 2.1e-258 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BPHMMAGG_01320 5e-104 pncA Q Isochorismatase family
BPHMMAGG_01321 7.7e-129 pnuC H nicotinamide mononucleotide transporter
BPHMMAGG_01322 9.5e-67 ltrA S Bacterial low temperature requirement A protein (LtrA)
BPHMMAGG_01323 6.8e-44 ltrA S Bacterial low temperature requirement A protein (LtrA)
BPHMMAGG_01324 1.6e-79 uspA T universal stress protein
BPHMMAGG_01325 1.4e-78 K AsnC family
BPHMMAGG_01326 1.6e-228 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
BPHMMAGG_01327 5.1e-97 dedA 3.1.3.1 S SNARE associated Golgi protein
BPHMMAGG_01328 5.4e-181 galR K Transcriptional regulator
BPHMMAGG_01329 3.1e-278 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
BPHMMAGG_01330 2.5e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BPHMMAGG_01331 2.4e-178 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
BPHMMAGG_01332 1.9e-144 ptp3 3.1.3.48 T Tyrosine phosphatase family
BPHMMAGG_01333 1.5e-91 yxkA S Phosphatidylethanolamine-binding protein
BPHMMAGG_01334 9.1e-36
BPHMMAGG_01335 2e-52
BPHMMAGG_01336 3.6e-202
BPHMMAGG_01337 1.1e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
BPHMMAGG_01338 2.4e-133 pnuC H nicotinamide mononucleotide transporter
BPHMMAGG_01339 2.2e-68 repB L Initiator Replication protein
BPHMMAGG_01341 4.3e-276 V Type II restriction enzyme, methylase subunits
BPHMMAGG_01342 6.8e-93 mrr L restriction endonuclease
BPHMMAGG_01343 3e-43 L recombinase activity
BPHMMAGG_01344 1.1e-15
BPHMMAGG_01353 4.5e-10 E Pfam:DUF955
BPHMMAGG_01354 2.7e-13 fic S Fic/DOC family
BPHMMAGG_01355 4.3e-24 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
BPHMMAGG_01357 7.5e-47 ebh D nuclear chromosome segregation
BPHMMAGG_01358 7e-13 K Cro/C1-type HTH DNA-binding domain
BPHMMAGG_01360 2.4e-43 hxlR K Transcriptional regulator, HxlR family
BPHMMAGG_01361 2.7e-159 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
BPHMMAGG_01362 3.6e-197
BPHMMAGG_01364 1.6e-109 dedA S SNARE-like domain protein
BPHMMAGG_01365 1.5e-102 S Protein of unknown function (DUF1461)
BPHMMAGG_01366 9.4e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
BPHMMAGG_01367 6.6e-93 yutD S Protein of unknown function (DUF1027)
BPHMMAGG_01368 1.6e-111 S Calcineurin-like phosphoesterase
BPHMMAGG_01369 1.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BPHMMAGG_01370 9.4e-144 ytxK 2.1.1.72 L N-6 DNA Methylase
BPHMMAGG_01372 1e-67
BPHMMAGG_01373 7.9e-40
BPHMMAGG_01374 2.4e-77 NU general secretion pathway protein
BPHMMAGG_01375 7.1e-47 comGC U competence protein ComGC
BPHMMAGG_01376 2e-178 comGB NU type II secretion system
BPHMMAGG_01377 1.1e-178 comGA NU Type II IV secretion system protein
BPHMMAGG_01378 3.5e-132 yebC K Transcriptional regulatory protein
BPHMMAGG_01379 1.8e-132
BPHMMAGG_01380 4.2e-181 ccpA K catabolite control protein A
BPHMMAGG_01381 1e-209 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
BPHMMAGG_01382 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
BPHMMAGG_01383 2.3e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
BPHMMAGG_01384 0.0 pacL 3.6.3.8 P P-type ATPase
BPHMMAGG_01385 3.8e-84 dps P Belongs to the Dps family
BPHMMAGG_01386 1.8e-51 yagE E amino acid
BPHMMAGG_01387 3e-54 yagE E amino acid
BPHMMAGG_01388 1.6e-109 yagE E amino acid
BPHMMAGG_01389 1.3e-114 gph 3.1.3.18 S HAD hydrolase, family IA, variant
BPHMMAGG_01390 2.7e-95 3.6.4.12 S PD-(D/E)XK nuclease family transposase
BPHMMAGG_01391 4.6e-35 3.6.4.12 S PD-(D/E)XK nuclease family transposase
BPHMMAGG_01392 6.4e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
BPHMMAGG_01393 9.5e-183 iunH2 3.2.2.1 F nucleoside hydrolase
BPHMMAGG_01394 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BPHMMAGG_01395 1.7e-167 T Calcineurin-like phosphoesterase superfamily domain
BPHMMAGG_01396 4.1e-223 mdtG EGP Major facilitator Superfamily
BPHMMAGG_01397 3.1e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
BPHMMAGG_01398 1.5e-258 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
BPHMMAGG_01399 1.3e-157 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
BPHMMAGG_01400 3.6e-177 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
BPHMMAGG_01401 9.9e-100 D nuclear chromosome segregation
BPHMMAGG_01402 0.0 lacZ 3.2.1.23 G -beta-galactosidase
BPHMMAGG_01403 1.2e-155 lacS G Transporter
BPHMMAGG_01404 3.7e-82 usp6 T universal stress protein
BPHMMAGG_01405 4.4e-46
BPHMMAGG_01406 8.5e-243 rarA L recombination factor protein RarA
BPHMMAGG_01407 2.7e-85 yueI S Protein of unknown function (DUF1694)
BPHMMAGG_01408 4.5e-21
BPHMMAGG_01409 8.1e-75 4.4.1.5 E Glyoxalase
BPHMMAGG_01410 2.5e-138 S Membrane
BPHMMAGG_01411 1e-139 S Belongs to the UPF0246 family
BPHMMAGG_01412 2.6e-186 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
BPHMMAGG_01413 3.1e-33 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
BPHMMAGG_01414 1.5e-32 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
BPHMMAGG_01415 8.2e-176 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
BPHMMAGG_01416 6.5e-63 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
BPHMMAGG_01417 1.1e-234 pbuG S permease
BPHMMAGG_01418 6.5e-270 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
BPHMMAGG_01419 5e-71 gadC E amino acid
BPHMMAGG_01420 4.8e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BPHMMAGG_01421 5.9e-244 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BPHMMAGG_01422 2.3e-215 iscS2 2.8.1.7 E Aminotransferase class V
BPHMMAGG_01423 3.2e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BPHMMAGG_01424 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
BPHMMAGG_01425 7.2e-272 cydA 1.10.3.14 C ubiquinol oxidase
BPHMMAGG_01426 4.5e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
BPHMMAGG_01427 1.2e-310 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
BPHMMAGG_01428 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BPHMMAGG_01429 1.8e-231 ndh 1.6.99.3 C NADH dehydrogenase
BPHMMAGG_01430 2.5e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
BPHMMAGG_01431 8e-122 radC L DNA repair protein
BPHMMAGG_01432 1.7e-179 mreB D cell shape determining protein MreB
BPHMMAGG_01433 3.5e-152 mreC M Involved in formation and maintenance of cell shape
BPHMMAGG_01434 8.7e-93 mreD M rod shape-determining protein MreD
BPHMMAGG_01435 3.2e-102 glnP P ABC transporter permease
BPHMMAGG_01436 1.2e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
BPHMMAGG_01437 1.7e-159 aatB ET ABC transporter substrate-binding protein
BPHMMAGG_01438 5.3e-226 ymfF S Peptidase M16 inactive domain protein
BPHMMAGG_01439 3.9e-248 ymfH S Peptidase M16
BPHMMAGG_01440 1.1e-136 ymfM S Helix-turn-helix domain
BPHMMAGG_01441 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BPHMMAGG_01442 4.3e-228 cinA 3.5.1.42 S Belongs to the CinA family
BPHMMAGG_01443 1.7e-196 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BPHMMAGG_01444 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
BPHMMAGG_01445 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BPHMMAGG_01446 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BPHMMAGG_01447 2.1e-100 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
BPHMMAGG_01448 6.5e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
BPHMMAGG_01449 2.2e-188 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
BPHMMAGG_01450 1.5e-29 yajC U Preprotein translocase
BPHMMAGG_01451 3.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
BPHMMAGG_01452 1.7e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
BPHMMAGG_01453 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BPHMMAGG_01454 4.1e-43 yrzL S Belongs to the UPF0297 family
BPHMMAGG_01455 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BPHMMAGG_01456 6.1e-48 yrzB S Belongs to the UPF0473 family
BPHMMAGG_01457 1.6e-86 cvpA S Colicin V production protein
BPHMMAGG_01458 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
BPHMMAGG_01459 6.1e-54 trxA O Belongs to the thioredoxin family
BPHMMAGG_01460 4.1e-98 yslB S Protein of unknown function (DUF2507)
BPHMMAGG_01461 3.1e-147 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
BPHMMAGG_01462 9.8e-106 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BPHMMAGG_01464 8.1e-114 K Transcriptional regulator
BPHMMAGG_01465 6.5e-293 M Exporter of polyketide antibiotics
BPHMMAGG_01466 1.1e-169 yjjC V ABC transporter
BPHMMAGG_01467 3.7e-07
BPHMMAGG_01468 3.1e-104 L Integrase
BPHMMAGG_01469 1.7e-33 S RelB antitoxin
BPHMMAGG_01470 3e-44
BPHMMAGG_01472 4.3e-204
BPHMMAGG_01473 7.7e-139 D CobQ CobB MinD ParA nucleotide binding domain protein
BPHMMAGG_01474 1.4e-33
BPHMMAGG_01475 1.6e-08 2.1.1.37, 2.1.1.72 L DNA restriction-modification system
BPHMMAGG_01476 2.1e-134 ksgA 2.1.1.182, 2.1.1.184 J Ribosomal RNA adenine dimethylase
BPHMMAGG_01477 2.2e-123 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
BPHMMAGG_01478 5e-311 cadA P P-type ATPase
BPHMMAGG_01479 1.3e-218 5.4.2.7 G Metalloenzyme superfamily
BPHMMAGG_01481 2.5e-95
BPHMMAGG_01482 2.6e-52 S Sugar efflux transporter for intercellular exchange
BPHMMAGG_01483 7.2e-245 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
BPHMMAGG_01485 0.0 L Helicase C-terminal domain protein
BPHMMAGG_01486 1.6e-64 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
BPHMMAGG_01487 1.2e-177 S Aldo keto reductase
BPHMMAGG_01489 8.5e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
BPHMMAGG_01490 5e-75 osmC O OsmC-like protein
BPHMMAGG_01491 3.2e-173 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BPHMMAGG_01492 1.2e-214 patA 2.6.1.1 E Aminotransferase
BPHMMAGG_01493 7.8e-32
BPHMMAGG_01494 0.0 clpL O associated with various cellular activities
BPHMMAGG_01496 2e-103 wecD3 K PFAM GCN5-related N-acetyltransferase
BPHMMAGG_01497 7.2e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BPHMMAGG_01498 4.3e-115 L transposase IS116 IS110 IS902 family protein
BPHMMAGG_01499 1.6e-196 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
BPHMMAGG_01500 1.6e-105 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
BPHMMAGG_01501 3.4e-155 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BPHMMAGG_01502 1.6e-59 M Glycosyl transferases group 1
BPHMMAGG_01504 7.4e-30 wzy S EpsG family
BPHMMAGG_01505 2.4e-32 M Glycosyltransferase like family 2
BPHMMAGG_01506 3e-87 tuaA M Bacterial sugar transferase
BPHMMAGG_01507 3.4e-137 cps2D 5.1.3.2 M RmlD substrate binding domain
BPHMMAGG_01508 3.2e-117 ywqD 2.7.10.1 D Capsular exopolysaccharide family
BPHMMAGG_01509 6.2e-133 epsB M biosynthesis protein
BPHMMAGG_01510 2.1e-161 brpA K Cell envelope-like function transcriptional attenuator common domain protein
BPHMMAGG_01511 7.4e-40 K Transcriptional regulator, HxlR family
BPHMMAGG_01512 1.9e-26 psiE S Phosphate-starvation-inducible E
BPHMMAGG_01513 4.1e-98 ydeN S Serine hydrolase
BPHMMAGG_01515 9.4e-181 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BPHMMAGG_01516 3.4e-253 nhaC C Na H antiporter NhaC
BPHMMAGG_01517 8.5e-37 S Cytochrome b5-like Heme/Steroid binding domain
BPHMMAGG_01518 4.1e-113 ywnB S NAD(P)H-binding
BPHMMAGG_01519 1.4e-36
BPHMMAGG_01520 1.7e-126 IQ Dehydrogenase reductase
BPHMMAGG_01521 4.4e-239 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
BPHMMAGG_01522 7.8e-53 L Psort location Cytoplasmic, score
BPHMMAGG_01523 6e-129 L Transposase
BPHMMAGG_01524 2.7e-23 3.2.1.18 GH33 M Rib/alpha-like repeat
BPHMMAGG_01526 7.1e-08 T Toxin-antitoxin system, toxin component, MazF family
BPHMMAGG_01527 5.9e-30
BPHMMAGG_01528 6.6e-07 D nuclear chromosome segregation
BPHMMAGG_01529 0.0 snf 2.7.11.1 KL domain protein
BPHMMAGG_01530 2e-143 ywqE 3.1.3.48 GM PHP domain protein
BPHMMAGG_01531 2e-208 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
BPHMMAGG_01532 0.0 sbcC L Putative exonuclease SbcCD, C subunit
BPHMMAGG_01533 1.5e-91 2.3.1.183 M Acetyltransferase GNAT family
BPHMMAGG_01534 2.2e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
BPHMMAGG_01535 6.4e-248 yxbA 6.3.1.12 S ATP-grasp enzyme
BPHMMAGG_01536 1.4e-289 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BPHMMAGG_01537 0.0 asnB 6.3.5.4 E Asparagine synthase
BPHMMAGG_01538 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
BPHMMAGG_01539 2.8e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BPHMMAGG_01540 6.3e-129 jag S R3H domain protein
BPHMMAGG_01543 5.3e-22 K Helix-turn-helix domain
BPHMMAGG_01544 1.5e-09 rpfI 3.1.3.48 D nuclear chromosome segregation
BPHMMAGG_01548 4e-54 S Plasmid replication protein
BPHMMAGG_01549 6.5e-15
BPHMMAGG_01550 1.2e-134 L Belongs to the 'phage' integrase family
BPHMMAGG_01551 5.2e-181 yfeX P Peroxidase
BPHMMAGG_01552 7.5e-275 arcD S C4-dicarboxylate anaerobic carrier
BPHMMAGG_01553 1e-259 ytjP 3.5.1.18 E Dipeptidase
BPHMMAGG_01554 1.7e-216 uhpT EGP Major facilitator Superfamily
BPHMMAGG_01555 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
BPHMMAGG_01556 1.8e-131 ponA V Beta-lactamase enzyme family
BPHMMAGG_01557 1.6e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
BPHMMAGG_01558 3e-75
BPHMMAGG_01559 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
BPHMMAGG_01560 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BPHMMAGG_01561 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BPHMMAGG_01562 1.6e-163 S Tetratricopeptide repeat
BPHMMAGG_01563 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BPHMMAGG_01564 1.1e-237 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
BPHMMAGG_01565 1.8e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BPHMMAGG_01566 1.4e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
BPHMMAGG_01567 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
BPHMMAGG_01568 0.0 lacS G Transporter
BPHMMAGG_01569 1.8e-38
BPHMMAGG_01570 7.1e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BPHMMAGG_01571 2.4e-286 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BPHMMAGG_01572 5.7e-190 yeaN P Transporter, major facilitator family protein
BPHMMAGG_01573 2.7e-73 S 3-demethylubiquinone-9 3-methyltransferase
BPHMMAGG_01574 2.7e-82 nrdI F Belongs to the NrdI family
BPHMMAGG_01575 1.5e-217 yhdP S Transporter associated domain
BPHMMAGG_01576 2.8e-154 ypdB V (ABC) transporter
BPHMMAGG_01577 2.5e-89 1.14.14.47, 1.6.5.3, 1.6.99.3 GM epimerase
BPHMMAGG_01578 1.1e-89 M1-874 K Domain of unknown function (DUF1836)
BPHMMAGG_01579 2.3e-78 yybA 2.3.1.57 K Transcriptional regulator
BPHMMAGG_01580 5.7e-132 XK27_07210 6.1.1.6 S B3 4 domain
BPHMMAGG_01581 2.6e-160 S AI-2E family transporter
BPHMMAGG_01582 1.3e-156 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
BPHMMAGG_01583 8.3e-160
BPHMMAGG_01584 1e-133 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
BPHMMAGG_01585 3.6e-138 eutJ E Hsp70 protein
BPHMMAGG_01586 8.3e-159 K helix_turn_helix, arabinose operon control protein
BPHMMAGG_01587 1.6e-37 pduA_4 CQ BMC
BPHMMAGG_01588 2.7e-134 pduB E BMC
BPHMMAGG_01589 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
BPHMMAGG_01590 3.9e-125 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
BPHMMAGG_01591 2.4e-71 pduE 4.2.1.28 Q Dehydratase small subunit
BPHMMAGG_01592 5.6e-309 pduG D Diol dehydratase reactivase ATPase-like domain
BPHMMAGG_01593 2.6e-45 pduH S Dehydratase medium subunit
BPHMMAGG_01594 1.8e-56 pduK CQ BMC
BPHMMAGG_01595 7.8e-40 pduA_4 CQ BMC
BPHMMAGG_01596 1.9e-115 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
BPHMMAGG_01597 1.3e-79 S Putative propanediol utilisation
BPHMMAGG_01598 5.2e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
BPHMMAGG_01599 1e-102 pduO 2.5.1.17 S Cobalamin adenosyltransferase
BPHMMAGG_01600 4.5e-77 pduO S Haem-degrading
BPHMMAGG_01601 3.1e-262 pduP 1.2.1.87 C Aldehyde dehydrogenase family
BPHMMAGG_01602 2.1e-202 pduQ C Iron-containing alcohol dehydrogenase
BPHMMAGG_01603 1.9e-217 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BPHMMAGG_01604 3e-54 pduU E BMC
BPHMMAGG_01605 1.1e-115 3.1.3.48 T Pfam:Y_phosphatase3C
BPHMMAGG_01606 1.9e-75 pgm1 3.1.3.73 G phosphoglycerate mutase
BPHMMAGG_01607 5.9e-68 P Cadmium resistance transporter
BPHMMAGG_01608 2.6e-68 eutP E Ethanolamine utilisation - propanediol utilisation
BPHMMAGG_01609 2.2e-73 fld C Flavodoxin
BPHMMAGG_01610 2.5e-115 XK27_04590 S NADPH-dependent FMN reductase
BPHMMAGG_01611 3.2e-77 cobO 2.5.1.17 S Cobalamin adenosyltransferase
BPHMMAGG_01612 1.4e-169 cobD 4.1.1.81 E Aminotransferase class I and II
BPHMMAGG_01613 7.3e-205 cbiA 6.3.5.11, 6.3.5.9 F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
BPHMMAGG_01614 1.7e-147 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BPHMMAGG_01615 9.3e-108 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
BPHMMAGG_01616 1.3e-186 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
BPHMMAGG_01617 1.6e-79 cbiE 2.1.1.132, 2.1.1.289 H Tetrapyrrole (Corrin/Porphyrin) Methylases
BPHMMAGG_01618 1.4e-77 cbiT 2.1.1.132, 2.1.1.196 H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
BPHMMAGG_01619 8.1e-129 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
BPHMMAGG_01620 3.3e-144 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
BPHMMAGG_01621 1.1e-127 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H Tetrapyrrole (Corrin/Porphyrin) Methylases
BPHMMAGG_01622 2.5e-98 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H Precorrin-6x reductase CbiJ/CobK
BPHMMAGG_01623 8.6e-177 cobA 2.1.1.107, 4.2.1.75 H Tetrapyrrole (Corrin/Porphyrin) Methylases
BPHMMAGG_01624 1.8e-107 cbiK 4.99.1.3 H Cobalt chelatase (CbiK)
BPHMMAGG_01625 2.3e-90 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Tetrapyrrole (Corrin/Porphyrin) Methylases
BPHMMAGG_01626 1e-123 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
BPHMMAGG_01627 7.6e-44 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
BPHMMAGG_01628 6.8e-103 cbiQ P Cobalt transport protein
BPHMMAGG_01629 3e-121 cbiO 2.1.1.195 P part of an ABC transporter complex. Responsible for energy coupling to the transport system
BPHMMAGG_01630 8.6e-239 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
BPHMMAGG_01631 7e-59 cysG 1.3.1.76, 4.99.1.4 H Putative NAD(P)-binding
BPHMMAGG_01632 4.1e-194 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BPHMMAGG_01633 2.6e-137 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
BPHMMAGG_01634 2.8e-174 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
BPHMMAGG_01635 3.9e-240 hemL 5.4.3.8 H Aminotransferase class-III
BPHMMAGG_01636 1.6e-76 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Cobinamide kinase / cobinamide phosphate guanyltransferase
BPHMMAGG_01637 4.9e-118 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BPHMMAGG_01638 5.8e-74 gpm 3.1.3.73, 5.4.2.12 G Belongs to the phosphoglycerate mutase family
BPHMMAGG_01639 6.5e-64 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
BPHMMAGG_01640 2e-146 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
BPHMMAGG_01641 3.1e-237 L Transposase
BPHMMAGG_01643 3.2e-36 mmuP E amino acid
BPHMMAGG_01644 1.6e-235 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
BPHMMAGG_01645 3.8e-281 2.4.1.5 GH13 G Glycosyl hydrolase family 70
BPHMMAGG_01646 8.6e-137 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BPHMMAGG_01647 1.1e-147 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
BPHMMAGG_01648 1.3e-114 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
BPHMMAGG_01649 1.8e-226 clcA_2 P Chloride transporter, ClC family
BPHMMAGG_01650 1.4e-34 L PFAM transposase IS116 IS110 IS902
BPHMMAGG_01651 1.6e-67 L PFAM transposase IS116 IS110 IS902
BPHMMAGG_01652 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
BPHMMAGG_01653 4.2e-110 lssY 3.6.1.27 I Acid phosphatase homologues
BPHMMAGG_01654 4.3e-08 L Transposase IS66 family
BPHMMAGG_01655 8.9e-206 nrnB S DHHA1 domain
BPHMMAGG_01656 6.2e-227 S Uncharacterized protein conserved in bacteria (DUF2325)
BPHMMAGG_01657 6e-247 brnQ U Component of the transport system for branched-chain amino acids
BPHMMAGG_01658 1.1e-104 NU mannosyl-glycoprotein
BPHMMAGG_01659 5e-142 S Putative ABC-transporter type IV
BPHMMAGG_01660 1.9e-273 S ABC transporter, ATP-binding protein
BPHMMAGG_01661 4.6e-18 K Helix-turn-helix domain
BPHMMAGG_01662 8.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
BPHMMAGG_01663 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
BPHMMAGG_01664 6.7e-119 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
BPHMMAGG_01665 1.5e-194 coiA 3.6.4.12 S Competence protein
BPHMMAGG_01666 6.8e-267 pipD E Dipeptidase
BPHMMAGG_01667 3.1e-113 yjbH Q Thioredoxin
BPHMMAGG_01668 2e-115 yjbM 2.7.6.5 S RelA SpoT domain protein
BPHMMAGG_01669 5.1e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BPHMMAGG_01670 1.6e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
BPHMMAGG_01671 1.7e-167 lsa S ABC transporter
BPHMMAGG_01672 5.1e-133 I alpha/beta hydrolase fold
BPHMMAGG_01673 1.8e-179 MA20_14895 S Conserved hypothetical protein 698
BPHMMAGG_01674 1.3e-93 S NADPH-dependent FMN reductase
BPHMMAGG_01675 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
BPHMMAGG_01676 3.6e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
BPHMMAGG_01677 5.7e-231 mntH P H( )-stimulated, divalent metal cation uptake system
BPHMMAGG_01678 7.1e-25
BPHMMAGG_01679 5.9e-155
BPHMMAGG_01680 4.8e-28
BPHMMAGG_01681 4.4e-152 3.1.3.73 G Belongs to the phosphoglycerate mutase family
BPHMMAGG_01682 5.2e-122 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
BPHMMAGG_01683 3.1e-101 fic D Fic/DOC family
BPHMMAGG_01684 2.8e-70
BPHMMAGG_01685 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
BPHMMAGG_01686 2.1e-88 L nuclease
BPHMMAGG_01687 6.3e-193 V Beta-lactamase
BPHMMAGG_01688 1.6e-94 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
BPHMMAGG_01689 1.8e-104 yhiD S MgtC family
BPHMMAGG_01690 7.4e-28 S GyrI-like small molecule binding domain
BPHMMAGG_01691 1.8e-53 S GyrI-like small molecule binding domain
BPHMMAGG_01693 8e-109 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
BPHMMAGG_01694 3.2e-50 azlD E Branched-chain amino acid transport
BPHMMAGG_01695 4.5e-118 azlC E azaleucine resistance protein AzlC
BPHMMAGG_01696 1.1e-259 K Aminotransferase class I and II
BPHMMAGG_01697 1.4e-231 S amidohydrolase
BPHMMAGG_01698 2.5e-33
BPHMMAGG_01699 4.6e-52 S Mazg nucleotide pyrophosphohydrolase
BPHMMAGG_01700 3.3e-160 xth 3.1.11.2 L exodeoxyribonuclease III
BPHMMAGG_01701 3.8e-10
BPHMMAGG_01702 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
BPHMMAGG_01703 5.1e-106 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BPHMMAGG_01704 2.3e-156 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
BPHMMAGG_01705 7.8e-199 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
BPHMMAGG_01706 4.2e-109 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
BPHMMAGG_01707 2.6e-163 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BPHMMAGG_01708 0.0 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
BPHMMAGG_01711 7.7e-15 S NADPH-dependent FMN reductase
BPHMMAGG_01712 1.1e-298 rafA 3.2.1.22 G alpha-galactosidase
BPHMMAGG_01713 2.9e-239 gph G Transporter
BPHMMAGG_01714 4e-81 msmR K helix_turn_helix, arabinose operon control protein
BPHMMAGG_01715 1.8e-34 XK27_08510 L Type III restriction protein res subunit
BPHMMAGG_01716 0.0 rafA 3.2.1.22 G alpha-galactosidase
BPHMMAGG_01717 1.5e-186 galR K Periplasmic binding protein-like domain
BPHMMAGG_01718 2.2e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
BPHMMAGG_01719 5.8e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
BPHMMAGG_01720 7.4e-31 lrgB M LrgB-like family
BPHMMAGG_01721 9.2e-28 lrgB M LrgB-like family
BPHMMAGG_01722 2.3e-32 lrgB M LrgB-like family
BPHMMAGG_01723 7.1e-66 lrgA S LrgA family
BPHMMAGG_01724 8.9e-81 lytT K response regulator receiver
BPHMMAGG_01725 7.4e-56 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
BPHMMAGG_01726 1.2e-183 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
BPHMMAGG_01727 3.9e-50 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
BPHMMAGG_01728 4e-148 f42a O Band 7 protein
BPHMMAGG_01729 3.7e-257 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
BPHMMAGG_01730 1e-153 yitU 3.1.3.104 S hydrolase
BPHMMAGG_01731 9.2e-39 S Cytochrome B5
BPHMMAGG_01732 3.4e-115 nreC K PFAM regulatory protein LuxR
BPHMMAGG_01733 5.2e-159 hipB K Helix-turn-helix
BPHMMAGG_01734 2.8e-57 yitW S Iron-sulfur cluster assembly protein
BPHMMAGG_01735 1.2e-271 sufB O assembly protein SufB
BPHMMAGG_01736 3.6e-79 nifU C SUF system FeS assembly protein, NifU family
BPHMMAGG_01737 1.2e-233 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BPHMMAGG_01738 5.1e-240 sufD O FeS assembly protein SufD
BPHMMAGG_01739 1.9e-144 sufC O FeS assembly ATPase SufC
BPHMMAGG_01740 2.8e-31 feoA P FeoA domain
BPHMMAGG_01741 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
BPHMMAGG_01742 2.2e-268 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
BPHMMAGG_01743 2.9e-156 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BPHMMAGG_01744 6.7e-60 ydiI Q Thioesterase superfamily
BPHMMAGG_01745 7.1e-109 yvrI K sigma factor activity
BPHMMAGG_01746 4.1e-78 G Transporter, major facilitator family protein
BPHMMAGG_01747 6.5e-100 G Transporter, major facilitator family protein
BPHMMAGG_01748 0.0 S Bacterial membrane protein YfhO
BPHMMAGG_01749 2.5e-103 T Ion transport 2 domain protein
BPHMMAGG_01750 2e-177 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
BPHMMAGG_01752 0.0 L PLD-like domain
BPHMMAGG_01753 1.3e-64 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
BPHMMAGG_01754 2.3e-35
BPHMMAGG_01755 0.0 L Type III restriction enzyme, res subunit
BPHMMAGG_01756 3.7e-09
BPHMMAGG_01757 5.2e-43 S SIR2-like domain
BPHMMAGG_01758 5.2e-52 yhaI S Protein of unknown function (DUF805)
BPHMMAGG_01759 2.2e-44
BPHMMAGG_01760 2.4e-22
BPHMMAGG_01761 1.2e-46
BPHMMAGG_01762 2.9e-96 K Acetyltransferase (GNAT) domain
BPHMMAGG_01763 3.6e-293 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
BPHMMAGG_01764 9e-232 gntT EG Gluconate
BPHMMAGG_01765 4.2e-181 K Transcriptional regulator, LacI family
BPHMMAGG_01766 8.3e-290 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
BPHMMAGG_01767 3.9e-93
BPHMMAGG_01768 1.8e-24
BPHMMAGG_01769 3.7e-61 asp S Asp23 family, cell envelope-related function
BPHMMAGG_01770 1.2e-85 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
BPHMMAGG_01772 1.2e-233 EGP Sugar (and other) transporter
BPHMMAGG_01773 6.7e-254 yfnA E Amino Acid
BPHMMAGG_01774 6.9e-74 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
BPHMMAGG_01775 1.5e-98 gmk2 2.7.4.8 F Guanylate kinase
BPHMMAGG_01776 5.6e-82 zur P Belongs to the Fur family
BPHMMAGG_01777 4e-17 3.2.1.14 GH18
BPHMMAGG_01778 7.1e-150
BPHMMAGG_01779 1.3e-270 pipD E Dipeptidase
BPHMMAGG_01780 1.8e-310 yjbQ P TrkA C-terminal domain protein
BPHMMAGG_01781 6.6e-24 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
BPHMMAGG_01782 2.1e-290 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BPHMMAGG_01783 6.7e-87
BPHMMAGG_01784 6.9e-121 S Alpha beta hydrolase
BPHMMAGG_01785 5.7e-217 dacA 3.4.16.4 M Belongs to the peptidase S11 family
BPHMMAGG_01786 1.7e-97
BPHMMAGG_01788 6.4e-122 yciB M ErfK YbiS YcfS YnhG
BPHMMAGG_01789 1.2e-260 S Putative peptidoglycan binding domain
BPHMMAGG_01790 1.1e-115 M Lysin motif
BPHMMAGG_01791 2.1e-79
BPHMMAGG_01792 3.1e-28 wecD3 K PFAM GCN5-related N-acetyltransferase
BPHMMAGG_01793 7e-56 wecD3 K PFAM GCN5-related N-acetyltransferase
BPHMMAGG_01794 5.9e-96 ltrA S Bacterial low temperature requirement A protein (LtrA)
BPHMMAGG_01795 8.5e-91 cytX U Belongs to the purine-cytosine permease (2.A.39) family
BPHMMAGG_01796 1.6e-103 cytX U Belongs to the purine-cytosine permease (2.A.39) family
BPHMMAGG_01797 4.3e-13
BPHMMAGG_01798 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
BPHMMAGG_01799 1.3e-145 potB P ABC transporter permease
BPHMMAGG_01800 2.5e-139 potC P ABC transporter permease
BPHMMAGG_01801 2.5e-208 potD P ABC transporter
BPHMMAGG_01802 2.8e-106
BPHMMAGG_01803 7e-42
BPHMMAGG_01805 2.9e-159 metQ_4 P Belongs to the nlpA lipoprotein family
BPHMMAGG_01806 2.6e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
BPHMMAGG_01807 8.7e-122 O Zinc-dependent metalloprotease
BPHMMAGG_01808 1e-36 L Helix-turn-helix domain
BPHMMAGG_01809 1.3e-16 L Transposase
BPHMMAGG_01810 9.5e-39 S Cytochrome B5
BPHMMAGG_01813 1.1e-118 sdaAB 4.3.1.17 E Serine dehydratase beta chain
BPHMMAGG_01814 9.7e-142 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
BPHMMAGG_01815 1.2e-105 ahpC 1.11.1.15 O Peroxiredoxin
BPHMMAGG_01816 0.0 trxB2 1.8.1.9 C Thioredoxin domain
BPHMMAGG_01817 1.3e-37 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BPHMMAGG_01818 4.6e-51 S CRISPR-associated protein (Cas_Csn2)
BPHMMAGG_01819 5.7e-186 lacR K Transcriptional regulator
BPHMMAGG_01820 8.7e-190 lacS G Transporter
BPHMMAGG_01823 3.7e-10 dnaQ 2.7.7.7 L Psort location Cytoplasmic, score 8.87
BPHMMAGG_01829 1.3e-10 glsA 3.5.1.2 E Belongs to the glutaminase family
BPHMMAGG_01830 4.8e-57 ytzB S Small secreted protein
BPHMMAGG_01831 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
BPHMMAGG_01832 2.9e-119 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
BPHMMAGG_01833 4.5e-252 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
BPHMMAGG_01834 1.9e-119 ybhL S Belongs to the BI1 family
BPHMMAGG_01835 1e-15 yoaK S Protein of unknown function (DUF1275)
BPHMMAGG_01836 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BPHMMAGG_01837 4.1e-158 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
BPHMMAGG_01838 3.4e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BPHMMAGG_01839 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BPHMMAGG_01840 5.9e-223 dnaB L replication initiation and membrane attachment
BPHMMAGG_01841 7.4e-172 dnaI L Primosomal protein DnaI
BPHMMAGG_01842 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BPHMMAGG_01843 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
BPHMMAGG_01844 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BPHMMAGG_01845 7e-95 yqeG S HAD phosphatase, family IIIA
BPHMMAGG_01846 2.1e-218 yqeH S Ribosome biogenesis GTPase YqeH
BPHMMAGG_01847 1.9e-47 yhbY J RNA-binding protein
BPHMMAGG_01848 2e-120 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BPHMMAGG_01849 6.2e-111 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
BPHMMAGG_01850 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
BPHMMAGG_01851 2.5e-135 yqeM Q Methyltransferase
BPHMMAGG_01852 5.3e-209 ylbM S Belongs to the UPF0348 family
BPHMMAGG_01853 4.9e-99 yceD S Uncharacterized ACR, COG1399
BPHMMAGG_01854 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
BPHMMAGG_01855 1.5e-121 K response regulator
BPHMMAGG_01856 5.4e-278 arlS 2.7.13.3 T Histidine kinase
BPHMMAGG_01857 4.3e-267 yjeM E Amino Acid
BPHMMAGG_01858 2.9e-235 V MatE
BPHMMAGG_01859 5.6e-68 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
BPHMMAGG_01860 5.9e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
BPHMMAGG_01861 1e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
BPHMMAGG_01862 1.8e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BPHMMAGG_01863 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
BPHMMAGG_01864 6.7e-59 yodB K Transcriptional regulator, HxlR family
BPHMMAGG_01865 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BPHMMAGG_01866 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
BPHMMAGG_01867 3.6e-114 rlpA M PFAM NLP P60 protein
BPHMMAGG_01868 8e-117 udk 2.7.1.48 F Cytidine monophosphokinase
BPHMMAGG_01869 5.3e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
BPHMMAGG_01870 3.1e-68 yneR S Belongs to the HesB IscA family
BPHMMAGG_01871 0.0 S membrane
BPHMMAGG_01872 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
BPHMMAGG_01873 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
BPHMMAGG_01874 5.2e-101 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BPHMMAGG_01875 3.9e-76 gluP 3.4.21.105 S Peptidase, S54 family
BPHMMAGG_01876 2.5e-20 gluP 3.4.21.105 S Peptidase, S54 family
BPHMMAGG_01877 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
BPHMMAGG_01878 5.6e-183 glk 2.7.1.2 G Glucokinase
BPHMMAGG_01879 3.4e-67 yqhL P Rhodanese-like protein
BPHMMAGG_01880 5.9e-22 S Protein of unknown function (DUF3042)
BPHMMAGG_01881 2.4e-175 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BPHMMAGG_01882 6.2e-265 glnA 6.3.1.2 E glutamine synthetase
BPHMMAGG_01883 8.4e-295 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BPHMMAGG_01884 6.8e-18 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
BPHMMAGG_01885 1.2e-174 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
BPHMMAGG_01886 3.9e-12
BPHMMAGG_01887 1.6e-154 P Belongs to the nlpA lipoprotein family
BPHMMAGG_01888 1.4e-98 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BPHMMAGG_01889 4.8e-51 S Iron-sulfur cluster assembly protein
BPHMMAGG_01890 2.6e-150
BPHMMAGG_01891 3.3e-181
BPHMMAGG_01892 2.8e-85 dut S Protein conserved in bacteria
BPHMMAGG_01895 3.4e-41 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
BPHMMAGG_01896 1.5e-29
BPHMMAGG_01897 2.6e-34 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BPHMMAGG_01898 3.4e-147 ykuT M mechanosensitive ion channel
BPHMMAGG_01899 1.4e-153 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
BPHMMAGG_01900 1.1e-74 ykuL S (CBS) domain
BPHMMAGG_01901 1.7e-93 S Phosphoesterase
BPHMMAGG_01902 1.6e-19
BPHMMAGG_01903 2.7e-54 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BPHMMAGG_01905 6.1e-260 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BPHMMAGG_01906 2.8e-73
BPHMMAGG_01907 4.4e-172
BPHMMAGG_01908 4.5e-175 fecB P Periplasmic binding protein
BPHMMAGG_01909 4e-80 M domain protein
BPHMMAGG_01910 2.8e-118 M domain protein
BPHMMAGG_01911 7.3e-237 M domain protein
BPHMMAGG_01912 1.2e-169 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BPHMMAGG_01913 1.1e-45 yitW S Pfam:DUF59
BPHMMAGG_01914 1e-68 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
BPHMMAGG_01915 1.4e-175 csd1 3.5.1.28 G domain, Protein
BPHMMAGG_01916 1.1e-163 yueF S AI-2E family transporter
BPHMMAGG_01937 3.1e-62 XK27_01125 L PFAM IS66 Orf2 family protein
BPHMMAGG_01938 5.4e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
BPHMMAGG_01939 2.2e-21
BPHMMAGG_01940 5.1e-262 S Uncharacterized protein conserved in bacteria (DUF2252)
BPHMMAGG_01941 2.3e-167 L transposase, IS605 OrfB family
BPHMMAGG_01942 4.4e-247 L PFAM plasmid pRiA4b ORF-3 family protein
BPHMMAGG_01943 1.9e-205 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
BPHMMAGG_01944 6.6e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BPHMMAGG_01945 4.3e-158 mleR K LysR family
BPHMMAGG_01946 6.3e-304 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
BPHMMAGG_01947 4e-259 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
BPHMMAGG_01948 5.8e-266 frdC 1.3.5.4 C FAD binding domain
BPHMMAGG_01949 3.5e-129 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
BPHMMAGG_01950 1.3e-201 P Sodium:sulfate symporter transmembrane region
BPHMMAGG_01951 1.4e-125 citR K sugar-binding domain protein
BPHMMAGG_01952 1.2e-176 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
BPHMMAGG_01953 7.4e-149 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
BPHMMAGG_01954 8.5e-42 citD C Covalent carrier of the coenzyme of citrate lyase
BPHMMAGG_01955 3.6e-160 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
BPHMMAGG_01956 7.1e-273 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
BPHMMAGG_01957 8e-154 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
BPHMMAGG_01958 3.8e-113 ydjP I Alpha/beta hydrolase family
BPHMMAGG_01959 3.3e-158 mleR K LysR family
BPHMMAGG_01960 1e-251 yjjP S Putative threonine/serine exporter
BPHMMAGG_01961 2.1e-117 ung2 3.2.2.27 L Uracil-DNA glycosylase
BPHMMAGG_01962 7.2e-270 emrY EGP Major facilitator Superfamily
BPHMMAGG_01963 5e-187 I Alpha beta
BPHMMAGG_01964 6.4e-102 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
BPHMMAGG_01965 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BPHMMAGG_01967 5.7e-163 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
BPHMMAGG_01968 7.1e-122 S Domain of unknown function (DUF4811)
BPHMMAGG_01969 7.2e-270 lmrB EGP Major facilitator Superfamily
BPHMMAGG_01970 4.9e-73 merR K MerR HTH family regulatory protein
BPHMMAGG_01971 3.9e-54
BPHMMAGG_01972 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BPHMMAGG_01973 8.3e-221 S CAAX protease self-immunity
BPHMMAGG_01974 3.6e-109 glnP P ABC transporter permease
BPHMMAGG_01975 2.4e-110 gluC P ABC transporter permease
BPHMMAGG_01976 3.3e-152 glnH ET ABC transporter
BPHMMAGG_01977 1.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
BPHMMAGG_01978 5.5e-83 usp1 T Belongs to the universal stress protein A family
BPHMMAGG_01979 4.2e-108 S VIT family
BPHMMAGG_01980 2.5e-116 S membrane
BPHMMAGG_01981 5.5e-164 czcD P cation diffusion facilitator family transporter
BPHMMAGG_01982 1.6e-123 sirR K iron dependent repressor
BPHMMAGG_01983 1e-30 cspC K Cold shock protein
BPHMMAGG_01984 2.6e-127 thrE S Putative threonine/serine exporter
BPHMMAGG_01985 1e-81 S Threonine/Serine exporter, ThrE
BPHMMAGG_01986 1.5e-118 lssY 3.6.1.27 I phosphatase
BPHMMAGG_01987 4.7e-08 2.3.1.128 J Acetyltransferase (GNAT) domain
BPHMMAGG_01988 4.3e-275 lysP E amino acid
BPHMMAGG_01989 2.8e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
BPHMMAGG_01995 7.7e-87 3.2.1.18 GH33 M Rib/alpha-like repeat
BPHMMAGG_01997 3.6e-76 2.1.1.72 S Adenine-specific methyltransferase EcoRI
BPHMMAGG_01998 2.1e-21
BPHMMAGG_01999 8.2e-63
BPHMMAGG_02000 1.2e-21 L Integrase
BPHMMAGG_02001 4.2e-32 S YozE SAM-like fold
BPHMMAGG_02002 1.8e-197 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
BPHMMAGG_02003 5.5e-185 L transposase, IS605 OrfB family
BPHMMAGG_02004 1.1e-51 L Transposase IS200 like
BPHMMAGG_02005 2.2e-221 L Transposase IS66 family
BPHMMAGG_02006 4.9e-176 L Transposase and inactivated derivatives, IS30 family
BPHMMAGG_02007 2.2e-58
BPHMMAGG_02008 1.5e-17
BPHMMAGG_02010 4.3e-186 yegS 2.7.1.107 G Lipid kinase
BPHMMAGG_02011 1.8e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BPHMMAGG_02012 7.7e-277 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
BPHMMAGG_02013 1.6e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BPHMMAGG_02014 3.3e-203 camS S sex pheromone
BPHMMAGG_02015 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BPHMMAGG_02016 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
BPHMMAGG_02017 9.7e-211 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BPHMMAGG_02018 2.3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
BPHMMAGG_02019 3e-113 acmC 3.2.1.96 NU mannosyl-glycoprotein
BPHMMAGG_02020 8e-140 IQ reductase
BPHMMAGG_02021 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
BPHMMAGG_02022 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BPHMMAGG_02023 5.5e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
BPHMMAGG_02024 9.8e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BPHMMAGG_02025 3.3e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BPHMMAGG_02026 4.2e-139 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BPHMMAGG_02027 1.1e-62 rplQ J Ribosomal protein L17
BPHMMAGG_02028 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BPHMMAGG_02029 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BPHMMAGG_02030 6.2e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BPHMMAGG_02031 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
BPHMMAGG_02032 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BPHMMAGG_02033 1.5e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
BPHMMAGG_02034 2.6e-239 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
BPHMMAGG_02035 5.8e-63 rplO J Binds to the 23S rRNA
BPHMMAGG_02036 2.9e-24 rpmD J Ribosomal protein L30
BPHMMAGG_02037 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BPHMMAGG_02038 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BPHMMAGG_02039 4.6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BPHMMAGG_02040 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BPHMMAGG_02041 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BPHMMAGG_02042 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BPHMMAGG_02043 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BPHMMAGG_02044 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BPHMMAGG_02045 1.9e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BPHMMAGG_02046 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
BPHMMAGG_02047 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BPHMMAGG_02048 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BPHMMAGG_02049 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BPHMMAGG_02050 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BPHMMAGG_02051 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BPHMMAGG_02052 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
BPHMMAGG_02053 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
BPHMMAGG_02054 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BPHMMAGG_02055 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
BPHMMAGG_02056 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BPHMMAGG_02057 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
BPHMMAGG_02058 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BPHMMAGG_02059 1.7e-106 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
BPHMMAGG_02060 2.3e-199 ykiI
BPHMMAGG_02061 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BPHMMAGG_02062 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BPHMMAGG_02063 1e-110 K Bacterial regulatory proteins, tetR family
BPHMMAGG_02064 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
BPHMMAGG_02065 4.4e-77 ctsR K Belongs to the CtsR family
BPHMMAGG_02066 2.1e-196 adhP 1.1.1.1 C alcohol dehydrogenase
BPHMMAGG_02067 1.5e-116 S Hydrolases of the alpha beta superfamily

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)