ORF_ID e_value Gene_name EC_number CAZy COGs Description
KMHNKCEJ_00001 1.3e-116 T PhoQ Sensor
KMHNKCEJ_00002 2.8e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KMHNKCEJ_00003 2.2e-229 L transposase, IS605 OrfB family
KMHNKCEJ_00004 4.9e-265 L PFAM Integrase catalytic region
KMHNKCEJ_00005 1.8e-259 S Uncharacterised protein family (UPF0236)
KMHNKCEJ_00006 5.5e-08 nudL L hydrolase
KMHNKCEJ_00007 5.1e-60 nudL L hydrolase
KMHNKCEJ_00008 3.9e-237 L Transposase
KMHNKCEJ_00009 2.4e-75 XK27_03180 T universal stress protein
KMHNKCEJ_00010 2.1e-55 recN L May be involved in recombinational repair of damaged DNA
KMHNKCEJ_00011 1.8e-09 thrC 4.2.3.1 E Threonine synthase
KMHNKCEJ_00012 1.3e-117 devA 3.6.3.25 V ABC transporter, ATP-binding protein
KMHNKCEJ_00013 4.7e-167 hrtB V ABC transporter permease
KMHNKCEJ_00014 3.7e-85 ygfC K transcriptional regulator (TetR family)
KMHNKCEJ_00015 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
KMHNKCEJ_00016 8.9e-287 mntH P H( )-stimulated, divalent metal cation uptake system
KMHNKCEJ_00017 2.3e-29
KMHNKCEJ_00018 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KMHNKCEJ_00020 8.6e-91 yxiO S Vacuole effluxer Atg22 like
KMHNKCEJ_00021 2.8e-56 yxiO S Vacuole effluxer Atg22 like
KMHNKCEJ_00022 9.8e-30 yxiO S Vacuole effluxer Atg22 like
KMHNKCEJ_00023 3.2e-153 npp S type I phosphodiesterase nucleotide pyrophosphatase
KMHNKCEJ_00024 7.9e-32 npp S type I phosphodiesterase nucleotide pyrophosphatase
KMHNKCEJ_00025 2.3e-238 E amino acid
KMHNKCEJ_00026 1.7e-67 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KMHNKCEJ_00027 2.8e-15 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KMHNKCEJ_00029 2e-219 yxjG_1 E methionine synthase, vitamin-B12 independent
KMHNKCEJ_00030 1.1e-28 S Cytochrome B5
KMHNKCEJ_00031 1.5e-74 elaA S Gnat family
KMHNKCEJ_00032 1.2e-120 GM NmrA-like family
KMHNKCEJ_00033 1.8e-50 hxlR K Transcriptional regulator, HxlR family
KMHNKCEJ_00034 1.2e-106 XK27_02070 S Nitroreductase family
KMHNKCEJ_00035 4e-83 K Transcriptional regulator, HxlR family
KMHNKCEJ_00036 5.7e-231
KMHNKCEJ_00037 2.2e-210 EGP Major facilitator Superfamily
KMHNKCEJ_00038 3e-256 pepC 3.4.22.40 E aminopeptidase
KMHNKCEJ_00039 5.3e-60 ylbE GM NAD dependent epimerase dehydratase family protein
KMHNKCEJ_00040 4.1e-43 ylbE GM NAD dependent epimerase dehydratase family protein
KMHNKCEJ_00041 0.0 pepN 3.4.11.2 E aminopeptidase
KMHNKCEJ_00042 1.9e-48 K Transcriptional regulator
KMHNKCEJ_00043 2.3e-24 folT S ECF transporter, substrate-specific component
KMHNKCEJ_00044 1.9e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
KMHNKCEJ_00045 2.7e-257 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
KMHNKCEJ_00046 2.8e-120 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
KMHNKCEJ_00047 5e-194 2.7.7.65 T GGDEF domain
KMHNKCEJ_00048 1.7e-82
KMHNKCEJ_00049 3.4e-247 pgaC GT2 M Glycosyl transferase
KMHNKCEJ_00050 2.7e-138 T EAL domain
KMHNKCEJ_00051 6.1e-128 yfeJ 6.3.5.2 F glutamine amidotransferase
KMHNKCEJ_00052 1.9e-59 yneR
KMHNKCEJ_00053 2.1e-101 qorB 1.6.5.2 GM NmrA-like family
KMHNKCEJ_00054 1.3e-159 akr5f 1.1.1.346 S reductase
KMHNKCEJ_00055 7.1e-145 K Transcriptional regulator
KMHNKCEJ_00056 2.3e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
KMHNKCEJ_00057 2.4e-160 ypuA S Protein of unknown function (DUF1002)
KMHNKCEJ_00058 6.6e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KMHNKCEJ_00059 5.1e-153 tesE Q hydratase
KMHNKCEJ_00060 3.7e-119 S Alpha beta hydrolase
KMHNKCEJ_00061 1.5e-65 lacA S transferase hexapeptide repeat
KMHNKCEJ_00062 7.8e-77 S Peptidase propeptide and YPEB domain
KMHNKCEJ_00063 1.4e-213 T GHKL domain
KMHNKCEJ_00064 1.1e-108 T Transcriptional regulatory protein, C terminal
KMHNKCEJ_00065 7e-19 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
KMHNKCEJ_00066 1.3e-64 ilvE 2.6.1.42 E Aminotransferase
KMHNKCEJ_00067 6.3e-81 ilvE 2.6.1.42 E Aminotransferase
KMHNKCEJ_00068 9.5e-112 S Haloacid dehalogenase-like hydrolase
KMHNKCEJ_00069 4.6e-160 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KMHNKCEJ_00070 4.8e-42 GK ROK family
KMHNKCEJ_00071 3.1e-20 GK ROK family
KMHNKCEJ_00072 1e-43 tnp L DDE domain
KMHNKCEJ_00073 2.1e-134 L integrase core domain
KMHNKCEJ_00074 2.2e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KMHNKCEJ_00075 2e-62 mreC M Involved in formation and maintenance of cell shape
KMHNKCEJ_00076 1.1e-91 tra L Transposase and inactivated derivatives, IS30 family
KMHNKCEJ_00077 2.8e-155 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
KMHNKCEJ_00078 7.2e-158 endA V DNA/RNA non-specific endonuclease
KMHNKCEJ_00079 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KMHNKCEJ_00080 2.3e-41 ybaN S Protein of unknown function (DUF454)
KMHNKCEJ_00081 7e-72 S Protein of unknown function (DUF3290)
KMHNKCEJ_00082 1.5e-112 yviA S Protein of unknown function (DUF421)
KMHNKCEJ_00083 1.5e-163 S Alpha/beta hydrolase of unknown function (DUF915)
KMHNKCEJ_00084 2.9e-17
KMHNKCEJ_00085 2.1e-90 ntd 2.4.2.6 F Nucleoside
KMHNKCEJ_00086 3.3e-152 3.1.3.102, 3.1.3.104 S hydrolase
KMHNKCEJ_00087 8.9e-41 yrvD S Pfam:DUF1049
KMHNKCEJ_00089 1.1e-139 L Belongs to the 'phage' integrase family
KMHNKCEJ_00091 1.6e-89
KMHNKCEJ_00094 7e-45
KMHNKCEJ_00096 1.1e-18
KMHNKCEJ_00099 1.8e-79 3.4.21.88 K Peptidase S24-like
KMHNKCEJ_00100 2.8e-10 K Helix-turn-helix XRE-family like proteins
KMHNKCEJ_00104 7.8e-54
KMHNKCEJ_00105 3.3e-20
KMHNKCEJ_00108 4.2e-116 L DnaD domain protein
KMHNKCEJ_00109 1.4e-86 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
KMHNKCEJ_00110 6e-137 L Belongs to the 'phage' integrase family
KMHNKCEJ_00112 2.3e-09
KMHNKCEJ_00113 3.3e-40 S HNH endonuclease
KMHNKCEJ_00115 4.4e-68
KMHNKCEJ_00116 2.4e-133
KMHNKCEJ_00121 1.3e-71 XK27_00160 S Domain of unknown function (DUF5052)
KMHNKCEJ_00123 4.2e-83 arpU S Phage transcriptional regulator, ArpU family
KMHNKCEJ_00124 9.1e-12
KMHNKCEJ_00125 1.2e-08
KMHNKCEJ_00126 8.6e-156 L HNH nucleases
KMHNKCEJ_00127 5.8e-77 terS L Phage terminase, small subunit
KMHNKCEJ_00128 0.0 terL S overlaps another CDS with the same product name
KMHNKCEJ_00132 3.2e-239 S Phage portal protein
KMHNKCEJ_00133 1.4e-113 pi136 S Caudovirus prohead serine protease
KMHNKCEJ_00134 2.8e-205 S Phage capsid family
KMHNKCEJ_00135 5.1e-69 S Phage gp6-like head-tail connector protein
KMHNKCEJ_00136 1.5e-39 S Phage head-tail joining protein
KMHNKCEJ_00137 7.2e-62 S Bacteriophage HK97-gp10, putative tail-component
KMHNKCEJ_00138 4.1e-74
KMHNKCEJ_00139 2.9e-108
KMHNKCEJ_00140 1.6e-23
KMHNKCEJ_00141 1.5e-19
KMHNKCEJ_00142 0.0 M Phage tail tape measure protein TP901
KMHNKCEJ_00143 2.1e-157 S Phage tail protein
KMHNKCEJ_00144 1e-260 3.4.24.40 M Peptidase family M23
KMHNKCEJ_00146 3.9e-31 S Domain of unknown function (DUF2479)
KMHNKCEJ_00152 2.5e-34
KMHNKCEJ_00153 1e-56 S Bacteriophage holin of superfamily 6 (Holin_LLH)
KMHNKCEJ_00154 3.6e-194 ps461 3.5.1.104 M hydrolase, family 25
KMHNKCEJ_00155 5.2e-56 badR K DNA-binding transcription factor activity
KMHNKCEJ_00156 9e-65 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KMHNKCEJ_00157 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KMHNKCEJ_00158 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KMHNKCEJ_00159 1.4e-18 D nuclear chromosome segregation
KMHNKCEJ_00161 6.6e-08
KMHNKCEJ_00162 2.8e-35 feoB P transporter of a GTP-driven Fe(2 ) uptake system
KMHNKCEJ_00163 5.7e-29
KMHNKCEJ_00164 3.8e-130 mltD CBM50 M NlpC P60 family protein
KMHNKCEJ_00166 6.5e-57
KMHNKCEJ_00167 6e-208 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KMHNKCEJ_00168 1.1e-218 EG GntP family permease
KMHNKCEJ_00169 8.5e-84 KT Putative sugar diacid recognition
KMHNKCEJ_00170 1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KMHNKCEJ_00171 8.5e-218 patA 2.6.1.1 E Aminotransferase
KMHNKCEJ_00172 8e-140 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KMHNKCEJ_00173 6.5e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KMHNKCEJ_00174 5.2e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KMHNKCEJ_00175 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KMHNKCEJ_00176 2.6e-244 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KMHNKCEJ_00177 2.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
KMHNKCEJ_00178 4.6e-180 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KMHNKCEJ_00179 3.1e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KMHNKCEJ_00180 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KMHNKCEJ_00181 1.9e-116 S Repeat protein
KMHNKCEJ_00182 2.9e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
KMHNKCEJ_00183 7.6e-224 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KMHNKCEJ_00184 7.5e-58 XK27_04120 S Putative amino acid metabolism
KMHNKCEJ_00185 4.6e-216 iscS 2.8.1.7 E Aminotransferase class V
KMHNKCEJ_00186 3.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KMHNKCEJ_00188 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
KMHNKCEJ_00189 4.2e-32 cspA K Cold shock protein
KMHNKCEJ_00190 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KMHNKCEJ_00191 2.3e-35 divIVA D DivIVA domain protein
KMHNKCEJ_00192 2.2e-145 ylmH S S4 domain protein
KMHNKCEJ_00193 3.2e-40 yggT S YGGT family
KMHNKCEJ_00194 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KMHNKCEJ_00195 3.5e-222 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KMHNKCEJ_00196 2.5e-253 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KMHNKCEJ_00197 1e-140 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KMHNKCEJ_00198 2.8e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KMHNKCEJ_00199 2.1e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KMHNKCEJ_00200 2.2e-179 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KMHNKCEJ_00201 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
KMHNKCEJ_00202 1.3e-55 ftsL D Cell division protein FtsL
KMHNKCEJ_00203 8.3e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KMHNKCEJ_00204 3.1e-77 mraZ K Belongs to the MraZ family
KMHNKCEJ_00205 1.7e-57
KMHNKCEJ_00206 1.2e-10 S Protein of unknown function (DUF4044)
KMHNKCEJ_00207 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KMHNKCEJ_00208 3e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KMHNKCEJ_00209 5.2e-156 rrmA 2.1.1.187 H Methyltransferase
KMHNKCEJ_00210 5.6e-181 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
KMHNKCEJ_00212 7.6e-41 K transcriptional
KMHNKCEJ_00213 1.9e-13 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KMHNKCEJ_00214 9.4e-12 cbiQ P cobalt transport
KMHNKCEJ_00215 3.9e-125 cbiQ P cobalt transport
KMHNKCEJ_00216 1.2e-76 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KMHNKCEJ_00217 6.2e-76 ctsR K Belongs to the CtsR family
KMHNKCEJ_00218 1.6e-43 KLT serine threonine protein kinase
KMHNKCEJ_00219 8e-131 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
KMHNKCEJ_00220 3.6e-70 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KMHNKCEJ_00224 4.9e-226 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
KMHNKCEJ_00225 2.9e-96 S reductase
KMHNKCEJ_00227 4.7e-88 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KMHNKCEJ_00228 6.5e-179 ABC-SBP S ABC transporter
KMHNKCEJ_00229 6.8e-84 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
KMHNKCEJ_00231 1.6e-214 htrA 3.4.21.107 O serine protease
KMHNKCEJ_00232 2.3e-153 vicX 3.1.26.11 S domain protein
KMHNKCEJ_00233 7.8e-149 yycI S YycH protein
KMHNKCEJ_00234 2.4e-245 yycH S YycH protein
KMHNKCEJ_00235 0.0 vicK 2.7.13.3 T Histidine kinase
KMHNKCEJ_00236 3.1e-130 K response regulator
KMHNKCEJ_00239 7.6e-308 lmrA 3.6.3.44 V ABC transporter
KMHNKCEJ_00240 6.8e-72 K helix_turn_helix multiple antibiotic resistance protein
KMHNKCEJ_00242 7.5e-96 Z012_01130 S Fic/DOC family
KMHNKCEJ_00244 6.9e-156 S Polyphosphate nucleotide phosphotransferase, PPK2 family
KMHNKCEJ_00245 9.1e-61
KMHNKCEJ_00246 2.6e-206 yttB EGP Major facilitator Superfamily
KMHNKCEJ_00247 1.8e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KMHNKCEJ_00248 2e-74 rplI J Binds to the 23S rRNA
KMHNKCEJ_00249 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KMHNKCEJ_00250 4.8e-99 deoR K sugar-binding domain protein
KMHNKCEJ_00251 1.2e-46 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KMHNKCEJ_00252 8.4e-32 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KMHNKCEJ_00253 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KMHNKCEJ_00254 4.8e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KMHNKCEJ_00255 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
KMHNKCEJ_00256 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KMHNKCEJ_00257 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KMHNKCEJ_00258 1.8e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KMHNKCEJ_00259 1.7e-34 yaaA S S4 domain protein YaaA
KMHNKCEJ_00260 5.7e-203 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KMHNKCEJ_00261 1.1e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KMHNKCEJ_00262 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
KMHNKCEJ_00263 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KMHNKCEJ_00264 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KMHNKCEJ_00265 6.3e-129 jag S R3H domain protein
KMHNKCEJ_00266 2.8e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KMHNKCEJ_00267 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KMHNKCEJ_00268 0.0 asnB 6.3.5.4 E Asparagine synthase
KMHNKCEJ_00269 9.3e-289 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KMHNKCEJ_00270 6.4e-248 yxbA 6.3.1.12 S ATP-grasp enzyme
KMHNKCEJ_00271 2.9e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KMHNKCEJ_00272 2.5e-14 2.3.1.183 M Acetyltransferase GNAT family
KMHNKCEJ_00273 1.4e-49 2.3.1.183 M Acetyltransferase GNAT family
KMHNKCEJ_00274 1.1e-19 yeiH S Membrane
KMHNKCEJ_00275 6.5e-128 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KMHNKCEJ_00277 2.4e-22 V ABC-2 type transporter
KMHNKCEJ_00278 3.6e-103 EG Permeases of the drug metabolite transporter (DMT) superfamily
KMHNKCEJ_00279 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
KMHNKCEJ_00281 1.3e-220 arcT 2.6.1.1 E Aminotransferase
KMHNKCEJ_00282 8e-255 E Arginine ornithine antiporter
KMHNKCEJ_00283 9e-281 yjeM E Amino Acid
KMHNKCEJ_00284 9.9e-142 yihY S Belongs to the UPF0761 family
KMHNKCEJ_00285 6.6e-34 S Protein of unknown function (DUF2922)
KMHNKCEJ_00286 4.9e-31
KMHNKCEJ_00287 1.2e-135 recX 2.4.1.337 GT4 S Regulatory protein RecX
KMHNKCEJ_00288 4.3e-146 cps1D M Domain of unknown function (DUF4422)
KMHNKCEJ_00289 2.5e-172 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
KMHNKCEJ_00290 5e-119 rfbP 2.7.8.6 M Bacterial sugar transferase
KMHNKCEJ_00291 0.0 2.7.7.6 M Peptidase family M23
KMHNKCEJ_00292 0.0 G Peptidase_C39 like family
KMHNKCEJ_00293 1.8e-24
KMHNKCEJ_00294 3.3e-219 glf 5.4.99.9 M UDP-galactopyranose mutase
KMHNKCEJ_00295 1.8e-209 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
KMHNKCEJ_00296 4.7e-76 M transferase activity, transferring glycosyl groups
KMHNKCEJ_00297 7.7e-89 cps3F
KMHNKCEJ_00298 3.9e-28 M biosynthesis protein
KMHNKCEJ_00299 3.8e-75 rgpB GT2 M Glycosyl transferase family 2
KMHNKCEJ_00300 1.4e-67 S Glycosyltransferase like family
KMHNKCEJ_00301 2e-81 glfT1 1.1.1.133 S Glycosyltransferase like family 2
KMHNKCEJ_00302 2.8e-68 S Acyltransferase family
KMHNKCEJ_00303 2.7e-11 S Acyltransferase family
KMHNKCEJ_00304 5.1e-79
KMHNKCEJ_00305 2.1e-145 rfbJ M Glycosyl transferase family 2
KMHNKCEJ_00306 1.6e-135
KMHNKCEJ_00307 0.0 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KMHNKCEJ_00308 2.2e-162 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KMHNKCEJ_00309 4.2e-109 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KMHNKCEJ_00310 2.3e-198 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KMHNKCEJ_00311 2e-157 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KMHNKCEJ_00312 0.0 csd1 3.5.1.28 G domain, Protein
KMHNKCEJ_00313 4.3e-163 yueF S AI-2E family transporter
KMHNKCEJ_00314 2.4e-225 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KMHNKCEJ_00315 6.9e-308 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KMHNKCEJ_00316 0.0 M NlpC/P60 family
KMHNKCEJ_00317 1.4e-101 mmuP E amino acid
KMHNKCEJ_00318 1e-116 L transposase IS116 IS110 IS902 family protein
KMHNKCEJ_00319 2.9e-125 yfmM S abc transporter atp-binding protein
KMHNKCEJ_00320 5.1e-116 yfbR S HD containing hydrolase-like enzyme
KMHNKCEJ_00321 1.5e-13
KMHNKCEJ_00322 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KMHNKCEJ_00323 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KMHNKCEJ_00324 3.2e-245 steT E amino acid
KMHNKCEJ_00325 1.9e-161 rapZ S Displays ATPase and GTPase activities
KMHNKCEJ_00326 2.1e-185 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KMHNKCEJ_00327 1.5e-169 whiA K May be required for sporulation
KMHNKCEJ_00329 8.8e-15
KMHNKCEJ_00330 8.8e-54 glpT G Major Facilitator Superfamily
KMHNKCEJ_00331 2.9e-103 glpT G Major Facilitator Superfamily
KMHNKCEJ_00332 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KMHNKCEJ_00334 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KMHNKCEJ_00335 1.7e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KMHNKCEJ_00336 1.8e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KMHNKCEJ_00337 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KMHNKCEJ_00338 1.4e-243 yifK E Amino acid permease
KMHNKCEJ_00339 2.4e-292 clcA P chloride
KMHNKCEJ_00340 1.8e-34 secG U Preprotein translocase
KMHNKCEJ_00341 5.9e-143 est 3.1.1.1 S Serine aminopeptidase, S33
KMHNKCEJ_00342 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KMHNKCEJ_00343 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KMHNKCEJ_00344 4.1e-104 yxjI
KMHNKCEJ_00345 9e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KMHNKCEJ_00346 1.1e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
KMHNKCEJ_00347 2e-80 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
KMHNKCEJ_00348 4.4e-86 K Acetyltransferase (GNAT) domain
KMHNKCEJ_00349 3.8e-75 S PAS domain
KMHNKCEJ_00350 2.7e-102 dnaQ 2.7.7.7 L DNA polymerase III
KMHNKCEJ_00351 1e-167 murB 1.3.1.98 M Cell wall formation
KMHNKCEJ_00352 2.5e-164 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KMHNKCEJ_00353 3e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KMHNKCEJ_00354 3.4e-247 fucP G Major Facilitator Superfamily
KMHNKCEJ_00355 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KMHNKCEJ_00356 3.8e-125 ybbR S YbbR-like protein
KMHNKCEJ_00357 1.2e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KMHNKCEJ_00358 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KMHNKCEJ_00359 6.5e-50 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KMHNKCEJ_00361 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KMHNKCEJ_00362 0.0 rafA 3.2.1.22 G alpha-galactosidase
KMHNKCEJ_00363 5.7e-186 galR K Periplasmic binding protein-like domain
KMHNKCEJ_00364 6.4e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
KMHNKCEJ_00365 4.4e-118 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KMHNKCEJ_00366 2.4e-87 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
KMHNKCEJ_00367 2.5e-46 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
KMHNKCEJ_00368 5.2e-148 f42a O Band 7 protein
KMHNKCEJ_00369 2.9e-254 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
KMHNKCEJ_00370 1e-153 yitU 3.1.3.104 S hydrolase
KMHNKCEJ_00371 9.2e-39 S Cytochrome B5
KMHNKCEJ_00372 3.4e-115 nreC K PFAM regulatory protein LuxR
KMHNKCEJ_00373 8.8e-159 hipB K Helix-turn-helix
KMHNKCEJ_00374 1.1e-56 yitW S Iron-sulfur cluster assembly protein
KMHNKCEJ_00375 1.2e-271 sufB O assembly protein SufB
KMHNKCEJ_00376 3.6e-79 nifU C SUF system FeS assembly protein, NifU family
KMHNKCEJ_00377 5.2e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KMHNKCEJ_00378 1.1e-239 sufD O FeS assembly protein SufD
KMHNKCEJ_00379 3.2e-144 sufC O FeS assembly ATPase SufC
KMHNKCEJ_00380 2.8e-31 feoA P FeoA domain
KMHNKCEJ_00381 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
KMHNKCEJ_00382 2.8e-268 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
KMHNKCEJ_00383 2.9e-156 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KMHNKCEJ_00384 6.7e-60 ydiI Q Thioesterase superfamily
KMHNKCEJ_00385 7.1e-109 yvrI K sigma factor activity
KMHNKCEJ_00386 3.4e-206 G Transporter, major facilitator family protein
KMHNKCEJ_00387 0.0 S Bacterial membrane protein YfhO
KMHNKCEJ_00388 7.3e-103 T Ion transport 2 domain protein
KMHNKCEJ_00389 9.9e-177 rihA F Inosine-uridine preferring nucleoside hydrolase
KMHNKCEJ_00391 0.0 L PLD-like domain
KMHNKCEJ_00392 1.3e-64 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
KMHNKCEJ_00393 2.3e-35
KMHNKCEJ_00394 0.0 L Type III restriction enzyme, res subunit
KMHNKCEJ_00395 5e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KMHNKCEJ_00396 2.5e-23 rpmD J ribosomal protein l30
KMHNKCEJ_00397 2.2e-60 K transcriptional regulator (lysR family)
KMHNKCEJ_00398 7.5e-91 L Transposase and inactivated derivatives, IS30 family
KMHNKCEJ_00399 6.7e-94 L PFAM Integrase, catalytic core
KMHNKCEJ_00400 1.2e-07 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
KMHNKCEJ_00401 5.9e-58 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KMHNKCEJ_00402 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
KMHNKCEJ_00403 1.9e-237 ktrB P Potassium uptake protein
KMHNKCEJ_00404 9.1e-116 ktrA P domain protein
KMHNKCEJ_00405 1.9e-79 Q Methyltransferase
KMHNKCEJ_00406 3.1e-229 mntH P H( )-stimulated, divalent metal cation uptake system
KMHNKCEJ_00407 3.1e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KMHNKCEJ_00408 1.8e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KMHNKCEJ_00409 4.6e-94 S NADPH-dependent FMN reductase
KMHNKCEJ_00410 2e-178 MA20_14895 S Conserved hypothetical protein 698
KMHNKCEJ_00411 3e-133 I alpha/beta hydrolase fold
KMHNKCEJ_00412 4e-143 lsa S ABC transporter
KMHNKCEJ_00413 6.1e-102 lsa S ABC transporter
KMHNKCEJ_00414 3e-181 yfeX P Peroxidase
KMHNKCEJ_00415 1.6e-233 arcD S C4-dicarboxylate anaerobic carrier
KMHNKCEJ_00416 9.5e-258 ytjP 3.5.1.18 E Dipeptidase
KMHNKCEJ_00417 6.3e-216 uhpT EGP Major facilitator Superfamily
KMHNKCEJ_00418 6.5e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
KMHNKCEJ_00419 5.3e-131 ponA V Beta-lactamase enzyme family
KMHNKCEJ_00420 6e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KMHNKCEJ_00421 5.3e-72
KMHNKCEJ_00422 2.3e-198 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
KMHNKCEJ_00423 2.2e-21
KMHNKCEJ_00424 9.3e-264 S Uncharacterized protein conserved in bacteria (DUF2252)
KMHNKCEJ_00425 2.6e-166 L transposase, IS605 OrfB family
KMHNKCEJ_00426 7.2e-295 L PFAM plasmid pRiA4b ORF-3 family protein
KMHNKCEJ_00427 1.9e-205 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
KMHNKCEJ_00428 6.6e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KMHNKCEJ_00429 9.7e-158 mleR K LysR family
KMHNKCEJ_00430 3.1e-303 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
KMHNKCEJ_00431 5.2e-259 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KMHNKCEJ_00432 6.9e-267 frdC 1.3.5.4 C FAD binding domain
KMHNKCEJ_00433 4.9e-252 yflS P Sodium:sulfate symporter transmembrane region
KMHNKCEJ_00435 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KMHNKCEJ_00436 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
KMHNKCEJ_00437 9.1e-33 L Integrase core domain protein
KMHNKCEJ_00438 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KMHNKCEJ_00439 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KMHNKCEJ_00440 6.9e-228 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
KMHNKCEJ_00441 3.9e-95 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KMHNKCEJ_00442 3.7e-114 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
KMHNKCEJ_00443 9.6e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KMHNKCEJ_00444 5.1e-128 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KMHNKCEJ_00445 1.9e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KMHNKCEJ_00446 7.3e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KMHNKCEJ_00447 5e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KMHNKCEJ_00448 5.1e-82 K LysR substrate binding domain
KMHNKCEJ_00449 9.4e-17 K LysR substrate binding domain
KMHNKCEJ_00450 1.6e-52 azlD S branched-chain amino acid
KMHNKCEJ_00451 2.7e-139 azlC E AzlC protein
KMHNKCEJ_00452 2.4e-201 hpk31 2.7.13.3 T Histidine kinase
KMHNKCEJ_00453 3.8e-125 K response regulator
KMHNKCEJ_00454 4.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KMHNKCEJ_00455 4e-170 deoR K sugar-binding domain protein
KMHNKCEJ_00456 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
KMHNKCEJ_00457 3.2e-234 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
KMHNKCEJ_00458 4.5e-235 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
KMHNKCEJ_00459 3.4e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KMHNKCEJ_00460 3.1e-136 XK27_01040 S Protein of unknown function (DUF1129)
KMHNKCEJ_00461 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KMHNKCEJ_00462 1.2e-31 yyzM S Bacterial protein of unknown function (DUF951)
KMHNKCEJ_00463 5e-154 spo0J K Belongs to the ParB family
KMHNKCEJ_00464 3.6e-140 soj D Sporulation initiation inhibitor
KMHNKCEJ_00465 1.5e-143 noc K Belongs to the ParB family
KMHNKCEJ_00466 3.7e-123 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
KMHNKCEJ_00467 7.7e-163 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
KMHNKCEJ_00468 6.6e-170 rihC 3.2.2.1 F Nucleoside
KMHNKCEJ_00469 1.3e-218 nupG F Nucleoside transporter
KMHNKCEJ_00470 1.6e-220 cycA E Amino acid permease
KMHNKCEJ_00471 1.9e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KMHNKCEJ_00472 2.2e-263 glnP P ABC transporter
KMHNKCEJ_00473 1.2e-249 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KMHNKCEJ_00474 6.3e-37 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
KMHNKCEJ_00475 2.7e-25 yclQ P ABC-type enterochelin transport system, periplasmic component
KMHNKCEJ_00476 1.5e-65 amiA E ABC transporter, substrate-binding protein, family 5
KMHNKCEJ_00477 1.4e-47 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KMHNKCEJ_00478 4.4e-53 adcB P ABC transporter (Permease
KMHNKCEJ_00479 3.7e-57 P cobalt transport protein
KMHNKCEJ_00481 1.2e-260 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KMHNKCEJ_00482 2.1e-185 yegS 2.7.1.107 G Lipid kinase
KMHNKCEJ_00483 1.8e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KMHNKCEJ_00484 1.6e-277 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KMHNKCEJ_00485 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KMHNKCEJ_00486 2.8e-202 camS S sex pheromone
KMHNKCEJ_00487 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KMHNKCEJ_00488 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KMHNKCEJ_00489 1.1e-209 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KMHNKCEJ_00490 2.3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KMHNKCEJ_00491 3e-113 acmC 3.2.1.96 NU mannosyl-glycoprotein
KMHNKCEJ_00492 8e-140 IQ reductase
KMHNKCEJ_00493 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
KMHNKCEJ_00494 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KMHNKCEJ_00495 5.5e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KMHNKCEJ_00496 6.3e-140 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KMHNKCEJ_00497 7.3e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KMHNKCEJ_00498 4.2e-139 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KMHNKCEJ_00499 1.1e-62 rplQ J Ribosomal protein L17
KMHNKCEJ_00500 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KMHNKCEJ_00501 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KMHNKCEJ_00502 6.2e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KMHNKCEJ_00503 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KMHNKCEJ_00504 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KMHNKCEJ_00505 4.4e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KMHNKCEJ_00506 1.7e-238 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KMHNKCEJ_00507 8.9e-64 rplO J Binds to the 23S rRNA
KMHNKCEJ_00508 2.9e-24 rpmD J Ribosomal protein L30
KMHNKCEJ_00509 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KMHNKCEJ_00510 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KMHNKCEJ_00511 2.1e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KMHNKCEJ_00512 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KMHNKCEJ_00513 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KMHNKCEJ_00514 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KMHNKCEJ_00515 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KMHNKCEJ_00516 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KMHNKCEJ_00517 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KMHNKCEJ_00518 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
KMHNKCEJ_00519 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KMHNKCEJ_00520 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KMHNKCEJ_00521 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KMHNKCEJ_00522 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KMHNKCEJ_00523 1.6e-149 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KMHNKCEJ_00524 4.9e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KMHNKCEJ_00525 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
KMHNKCEJ_00526 4.3e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KMHNKCEJ_00527 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
KMHNKCEJ_00528 2.6e-29
KMHNKCEJ_00529 8.8e-35 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KMHNKCEJ_00530 2.2e-146 ykuT M mechanosensitive ion channel
KMHNKCEJ_00531 1e-153 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
KMHNKCEJ_00532 1.1e-74 ykuL S (CBS) domain
KMHNKCEJ_00533 1.7e-93 S Phosphoesterase
KMHNKCEJ_00534 9.8e-106 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KMHNKCEJ_00535 3.1e-147 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KMHNKCEJ_00536 1.6e-97 yslB S Protein of unknown function (DUF2507)
KMHNKCEJ_00537 1.8e-53 trxA O Belongs to the thioredoxin family
KMHNKCEJ_00538 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KMHNKCEJ_00539 2.7e-86 cvpA S Colicin V production protein
KMHNKCEJ_00540 6.1e-48 yrzB S Belongs to the UPF0473 family
KMHNKCEJ_00541 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KMHNKCEJ_00542 4.1e-43 yrzL S Belongs to the UPF0297 family
KMHNKCEJ_00543 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KMHNKCEJ_00544 3.7e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KMHNKCEJ_00545 3.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
KMHNKCEJ_00546 6.2e-31 yajC U Preprotein translocase
KMHNKCEJ_00547 5.9e-189 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KMHNKCEJ_00548 2.9e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KMHNKCEJ_00549 4.3e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KMHNKCEJ_00550 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KMHNKCEJ_00551 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KMHNKCEJ_00552 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
KMHNKCEJ_00553 1.9e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KMHNKCEJ_00554 1.4e-226 cinA 3.5.1.42 S Belongs to the CinA family
KMHNKCEJ_00555 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KMHNKCEJ_00556 1.7e-137 ymfM S Helix-turn-helix domain
KMHNKCEJ_00557 2.5e-247 ymfH S Peptidase M16
KMHNKCEJ_00558 1.6e-227 ymfF S Peptidase M16 inactive domain protein
KMHNKCEJ_00559 2.9e-159 aatB ET ABC transporter substrate-binding protein
KMHNKCEJ_00560 1.2e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KMHNKCEJ_00561 4.2e-102 glnP P ABC transporter permease
KMHNKCEJ_00562 8.7e-93 mreD M rod shape-determining protein MreD
KMHNKCEJ_00563 3.5e-152 mreC M Involved in formation and maintenance of cell shape
KMHNKCEJ_00564 1.7e-179 mreB D cell shape determining protein MreB
KMHNKCEJ_00565 8e-122 radC L DNA repair protein
KMHNKCEJ_00566 2.5e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KMHNKCEJ_00567 1.8e-231 ndh 1.6.99.3 C NADH dehydrogenase
KMHNKCEJ_00568 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KMHNKCEJ_00569 7e-311 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
KMHNKCEJ_00570 4.5e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
KMHNKCEJ_00571 7.2e-272 cydA 1.10.3.14 C ubiquinol oxidase
KMHNKCEJ_00572 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KMHNKCEJ_00573 3.2e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KMHNKCEJ_00574 8.6e-215 iscS2 2.8.1.7 E Aminotransferase class V
KMHNKCEJ_00575 9.7e-239 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KMHNKCEJ_00576 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KMHNKCEJ_00577 1.6e-66 gadC E amino acid
KMHNKCEJ_00578 4.6e-156 gadC E amino acid
KMHNKCEJ_00579 1.1e-275 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
KMHNKCEJ_00580 4.3e-234 pbuG S permease
KMHNKCEJ_00581 5.3e-231 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
KMHNKCEJ_00582 3.1e-13 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
KMHNKCEJ_00583 5.3e-33 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
KMHNKCEJ_00584 1.2e-258 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
KMHNKCEJ_00585 1e-139 S Belongs to the UPF0246 family
KMHNKCEJ_00586 1.5e-22 S Membrane
KMHNKCEJ_00587 6.3e-96 S Membrane
KMHNKCEJ_00588 8.1e-75 4.4.1.5 E Glyoxalase
KMHNKCEJ_00589 4.5e-21
KMHNKCEJ_00590 2.7e-85 yueI S Protein of unknown function (DUF1694)
KMHNKCEJ_00591 1.4e-234 rarA L recombination factor protein RarA
KMHNKCEJ_00592 1.3e-45
KMHNKCEJ_00593 4.3e-83 usp6 T universal stress protein
KMHNKCEJ_00594 5.9e-205 araR K Transcriptional regulator
KMHNKCEJ_00595 2.5e-155 ytbE 1.1.1.346 S Aldo keto reductase
KMHNKCEJ_00596 2.4e-90 maa 2.3.1.79 S Maltose O-acetyltransferase
KMHNKCEJ_00597 1.4e-283 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
KMHNKCEJ_00598 3.7e-139 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
KMHNKCEJ_00599 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
KMHNKCEJ_00600 1.2e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KMHNKCEJ_00601 3.7e-146 2.3.1.19 K Helix-turn-helix XRE-family like proteins
KMHNKCEJ_00602 5.3e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KMHNKCEJ_00603 1.4e-47 gcvH E glycine cleavage
KMHNKCEJ_00604 4.1e-220 rodA D Belongs to the SEDS family
KMHNKCEJ_00605 1e-31 S Protein of unknown function (DUF2969)
KMHNKCEJ_00606 1.9e-178 mbl D Cell shape determining protein MreB Mrl
KMHNKCEJ_00607 2.3e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KMHNKCEJ_00608 1.3e-33 ywzB S Protein of unknown function (DUF1146)
KMHNKCEJ_00609 1e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KMHNKCEJ_00610 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KMHNKCEJ_00611 7.4e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KMHNKCEJ_00612 1.5e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KMHNKCEJ_00613 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KMHNKCEJ_00614 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KMHNKCEJ_00615 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KMHNKCEJ_00616 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
KMHNKCEJ_00617 5.9e-233 pyrP F Permease
KMHNKCEJ_00618 2.6e-130 yibF S overlaps another CDS with the same product name
KMHNKCEJ_00619 4.4e-192 yibE S overlaps another CDS with the same product name
KMHNKCEJ_00620 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KMHNKCEJ_00621 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KMHNKCEJ_00622 2.3e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KMHNKCEJ_00623 1.4e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KMHNKCEJ_00624 6.6e-167 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KMHNKCEJ_00625 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KMHNKCEJ_00626 6e-108 tdk 2.7.1.21 F thymidine kinase
KMHNKCEJ_00627 4.1e-261 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
KMHNKCEJ_00628 7.1e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
KMHNKCEJ_00629 3e-10
KMHNKCEJ_00630 6.1e-223 arcD U Amino acid permease
KMHNKCEJ_00631 4.1e-259 E Arginine ornithine antiporter
KMHNKCEJ_00632 2.7e-79 argR K Regulates arginine biosynthesis genes
KMHNKCEJ_00633 5.8e-217 arcA 3.5.3.6 E Arginine
KMHNKCEJ_00634 5.3e-184 ampC V Beta-lactamase
KMHNKCEJ_00635 1.8e-19
KMHNKCEJ_00636 2.7e-77 ypuA S secreted protein
KMHNKCEJ_00637 1.7e-94 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
KMHNKCEJ_00638 2.2e-52 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KMHNKCEJ_00639 1.4e-101 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KMHNKCEJ_00641 2.5e-119 K LysR substrate binding domain
KMHNKCEJ_00642 8.3e-96 V VanZ like family
KMHNKCEJ_00644 1.6e-26
KMHNKCEJ_00646 5.2e-146 L Transposase and inactivated derivatives IS30 family
KMHNKCEJ_00648 2.8e-290 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KMHNKCEJ_00649 2.4e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KMHNKCEJ_00650 9.7e-169 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KMHNKCEJ_00651 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KMHNKCEJ_00652 1.3e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KMHNKCEJ_00653 3.1e-251 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KMHNKCEJ_00654 3.7e-63 yabR J RNA binding
KMHNKCEJ_00655 1.3e-55 divIC D Septum formation initiator
KMHNKCEJ_00656 2.1e-39 yabO J S4 domain protein
KMHNKCEJ_00657 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KMHNKCEJ_00658 3.3e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KMHNKCEJ_00659 6.9e-113 S (CBS) domain
KMHNKCEJ_00660 1.9e-144 tesE Q hydratase
KMHNKCEJ_00661 2.3e-242 codA 3.5.4.1 F cytosine deaminase
KMHNKCEJ_00662 3.1e-251 U Belongs to the purine-cytosine permease (2.A.39) family
KMHNKCEJ_00663 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
KMHNKCEJ_00664 1.1e-209 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KMHNKCEJ_00665 3.2e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KMHNKCEJ_00667 8.5e-295 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMHNKCEJ_00668 6.7e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
KMHNKCEJ_00669 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMHNKCEJ_00670 1.5e-252 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KMHNKCEJ_00671 1.4e-170 glsA 3.5.1.2 E Belongs to the glutaminase family
KMHNKCEJ_00672 1.3e-89 L Bacterial dnaA protein
KMHNKCEJ_00673 1.7e-80 metI P ABC transporter (Permease
KMHNKCEJ_00674 1.7e-106 L hmm pf00665
KMHNKCEJ_00675 2.8e-88 G Belongs to the phosphoglycerate mutase family
KMHNKCEJ_00676 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
KMHNKCEJ_00677 5.9e-211 EGP Major facilitator Superfamily
KMHNKCEJ_00678 3.9e-135 V ABC transporter
KMHNKCEJ_00679 9e-106
KMHNKCEJ_00680 4e-14
KMHNKCEJ_00681 7.1e-63
KMHNKCEJ_00682 1.5e-194 lplA 6.3.1.20 H Lipoate-protein ligase
KMHNKCEJ_00683 6.6e-81 uspA T universal stress protein
KMHNKCEJ_00684 0.0 tetP J elongation factor G
KMHNKCEJ_00685 2.9e-165 GK ROK family
KMHNKCEJ_00686 1.6e-236 brnQ U Component of the transport system for branched-chain amino acids
KMHNKCEJ_00687 3.2e-138 aroD S Serine hydrolase (FSH1)
KMHNKCEJ_00688 5.5e-237 yagE E amino acid
KMHNKCEJ_00689 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
KMHNKCEJ_00690 4.7e-126 gntR K UbiC transcription regulator-associated domain protein
KMHNKCEJ_00691 1.6e-85 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KMHNKCEJ_00692 2.6e-269 pipD E Dipeptidase
KMHNKCEJ_00693 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
KMHNKCEJ_00694 0.0 yfiC V ABC transporter
KMHNKCEJ_00695 8.3e-286 lmrA V ABC transporter, ATP-binding protein
KMHNKCEJ_00696 1.7e-17 K Winged helix DNA-binding domain
KMHNKCEJ_00697 1.9e-179 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KMHNKCEJ_00698 2.9e-19 S PFAM Archaeal ATPase
KMHNKCEJ_00699 5.9e-73 S ECF transporter, substrate-specific component
KMHNKCEJ_00700 9.8e-51 S Domain of unknown function (DUF4430)
KMHNKCEJ_00701 8.6e-20 cnrT EG PFAM EamA-like transporter family
KMHNKCEJ_00702 1.2e-117 tnp L MULE transposase domain
KMHNKCEJ_00703 3.3e-85 L PFAM transposase IS200-family protein
KMHNKCEJ_00704 1.6e-09 S D-Ala-teichoic acid biosynthesis protein
KMHNKCEJ_00705 1.4e-83 xth 3.1.11.2 L exodeoxyribonuclease III
KMHNKCEJ_00706 1.7e-63 malX G maltose binding
KMHNKCEJ_00707 1.2e-59 V 'abc transporter, ATP-binding protein
KMHNKCEJ_00708 5.6e-52
KMHNKCEJ_00709 0.0 oatA I Acyltransferase
KMHNKCEJ_00710 1.8e-78 K Transcriptional regulator
KMHNKCEJ_00711 1.1e-147 XK27_02985 S Cof-like hydrolase
KMHNKCEJ_00712 1.3e-76 lytE M Lysin motif
KMHNKCEJ_00714 1.6e-134 K response regulator
KMHNKCEJ_00715 2.6e-272 yclK 2.7.13.3 T Histidine kinase
KMHNKCEJ_00716 4.1e-153 glcU U sugar transport
KMHNKCEJ_00717 9.6e-96 lacA 2.3.1.79 S Transferase hexapeptide repeat
KMHNKCEJ_00718 6.5e-262 pgi 5.3.1.9 G Belongs to the GPI family
KMHNKCEJ_00719 1e-25
KMHNKCEJ_00721 3.1e-30 xylB 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
KMHNKCEJ_00722 3.6e-154 KT YcbB domain
KMHNKCEJ_00723 7.6e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KMHNKCEJ_00724 2.1e-171 arcC 2.7.2.2 E Belongs to the carbamate kinase family
KMHNKCEJ_00725 9.6e-161 EG EamA-like transporter family
KMHNKCEJ_00726 8.4e-39 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
KMHNKCEJ_00727 4.5e-48 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
KMHNKCEJ_00728 0.0 copA 3.6.3.54 P P-type ATPase
KMHNKCEJ_00729 1.6e-85
KMHNKCEJ_00731 1.8e-56
KMHNKCEJ_00732 1.3e-109 yjcE P Sodium proton antiporter
KMHNKCEJ_00733 4.6e-101 yjcE P Sodium proton antiporter
KMHNKCEJ_00735 5.8e-91
KMHNKCEJ_00736 6.4e-263 M domain protein
KMHNKCEJ_00737 2.9e-158 M domain protein
KMHNKCEJ_00738 9.4e-15 M LysM domain
KMHNKCEJ_00739 1.3e-34 ykuJ S protein conserved in bacteria
KMHNKCEJ_00740 1.3e-41 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KMHNKCEJ_00741 2.9e-84 XK27_03960 S Protein of unknown function (DUF3013)
KMHNKCEJ_00743 1.4e-51 L PFAM Integrase catalytic region
KMHNKCEJ_00744 3.1e-99 epsB M biosynthesis protein
KMHNKCEJ_00745 1e-107 ywqD 2.7.10.1 D Capsular exopolysaccharide family
KMHNKCEJ_00746 8.9e-49 pglC M Bacterial sugar transferase
KMHNKCEJ_00747 1.2e-86 GT4 G Glycosyl transferase 4-like
KMHNKCEJ_00748 3e-67 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
KMHNKCEJ_00749 5.4e-42 M cog cog1442
KMHNKCEJ_00751 2.2e-72 cps2I S Psort location CytoplasmicMembrane, score
KMHNKCEJ_00752 1.2e-28 M Glycosyltransferase sugar-binding region containing DXD motif
KMHNKCEJ_00753 1e-27 M PFAM Glycosyl transferase family 2
KMHNKCEJ_00754 7.2e-29 S COG0463 Glycosyltransferases involved in cell wall biogenesis
KMHNKCEJ_00755 1e-50 S Glycosyltransferase, group 2 family protein
KMHNKCEJ_00757 9.1e-30 S Acyltransferase family
KMHNKCEJ_00758 0.0 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
KMHNKCEJ_00759 1.5e-282 2.4.1.5 GH13 G Glycosyl hydrolase family 70
KMHNKCEJ_00760 1.7e-72 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KMHNKCEJ_00761 9.5e-39 S Cytochrome B5
KMHNKCEJ_00762 2.3e-78 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KMHNKCEJ_00763 1.7e-82 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMHNKCEJ_00764 3.5e-68 trkH P Cation transport protein
KMHNKCEJ_00765 0.0 FbpA K Fibronectin-binding protein
KMHNKCEJ_00766 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
KMHNKCEJ_00767 1.4e-206 carA 6.3.5.5 F Belongs to the CarA family
KMHNKCEJ_00768 4.5e-174 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KMHNKCEJ_00769 1.7e-73 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KMHNKCEJ_00770 5.6e-65 esbA S Family of unknown function (DUF5322)
KMHNKCEJ_00771 9e-71 rnhA 3.1.26.4 L Ribonuclease HI
KMHNKCEJ_00772 7.3e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KMHNKCEJ_00773 8e-82 F Belongs to the NrdI family
KMHNKCEJ_00774 1.2e-42 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KMHNKCEJ_00775 3.2e-101 ypsA S Belongs to the UPF0398 family
KMHNKCEJ_00776 2.4e-115 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KMHNKCEJ_00777 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
KMHNKCEJ_00778 1.3e-160 EG EamA-like transporter family
KMHNKCEJ_00779 8.1e-123 dnaD L DnaD domain protein
KMHNKCEJ_00780 6.9e-87 ypmB S Protein conserved in bacteria
KMHNKCEJ_00781 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KMHNKCEJ_00782 6.3e-171 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
KMHNKCEJ_00783 1.7e-163 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
KMHNKCEJ_00784 1.8e-212 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
KMHNKCEJ_00785 6.4e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KMHNKCEJ_00786 2.5e-86 S Protein of unknown function (DUF1440)
KMHNKCEJ_00787 7e-122 L Transposase
KMHNKCEJ_00789 1.3e-27 ymfF S Peptidase M16
KMHNKCEJ_00790 0.0 trxB2 1.8.1.9 C Thioredoxin domain
KMHNKCEJ_00791 1.2e-105 ahpC 1.11.1.15 O Peroxiredoxin
KMHNKCEJ_00792 4.1e-140 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
KMHNKCEJ_00793 1.1e-121 sdaAB 4.3.1.17 E Serine dehydratase beta chain
KMHNKCEJ_00796 2.7e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KMHNKCEJ_00797 1.7e-167 T Calcineurin-like phosphoesterase superfamily domain
KMHNKCEJ_00798 7e-223 mdtG EGP Major facilitator Superfamily
KMHNKCEJ_00799 5.7e-129 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KMHNKCEJ_00800 4.4e-53 yxjG_1 E methionine synthase, vitamin-B12 independent
KMHNKCEJ_00801 4.4e-158 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
KMHNKCEJ_00802 1.2e-177 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KMHNKCEJ_00803 0.0 lacZ 3.2.1.23 G -beta-galactosidase
KMHNKCEJ_00804 0.0 lacS G Transporter
KMHNKCEJ_00805 2.8e-185 lacR K Transcriptional regulator
KMHNKCEJ_00806 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KMHNKCEJ_00807 3.3e-09
KMHNKCEJ_00808 4.7e-38
KMHNKCEJ_00809 3.3e-160 xth 3.1.11.2 L exodeoxyribonuclease III
KMHNKCEJ_00810 1.2e-52 S Mazg nucleotide pyrophosphohydrolase
KMHNKCEJ_00811 3.6e-32
KMHNKCEJ_00812 6.2e-32 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KMHNKCEJ_00813 1.6e-102 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KMHNKCEJ_00815 1.4e-50 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KMHNKCEJ_00816 3.4e-65 rmaI K Transcriptional regulator
KMHNKCEJ_00817 5.1e-152 EGP Major facilitator Superfamily
KMHNKCEJ_00818 1.2e-56 EGP Major facilitator Superfamily
KMHNKCEJ_00819 1.5e-107 yvyE 3.4.13.9 S YigZ family
KMHNKCEJ_00820 1.1e-250 comFA L Helicase C-terminal domain protein
KMHNKCEJ_00821 1.4e-93 comFC S Competence protein
KMHNKCEJ_00822 4.5e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KMHNKCEJ_00823 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KMHNKCEJ_00824 1.7e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KMHNKCEJ_00825 7.7e-31 KT PspC domain protein
KMHNKCEJ_00826 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
KMHNKCEJ_00827 1.7e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KMHNKCEJ_00828 9.4e-155 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KMHNKCEJ_00829 1.9e-181 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KMHNKCEJ_00830 2.8e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KMHNKCEJ_00831 4.6e-137 yrjD S LUD domain
KMHNKCEJ_00832 3e-289 lutB C 4Fe-4S dicluster domain
KMHNKCEJ_00833 7.8e-168 lutA C Cysteine-rich domain
KMHNKCEJ_00834 1.7e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KMHNKCEJ_00835 1.8e-204 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
KMHNKCEJ_00836 6.5e-162 aatB ET PFAM extracellular solute-binding protein, family 3
KMHNKCEJ_00837 2.1e-88 ykhA 3.1.2.20 I Thioesterase superfamily
KMHNKCEJ_00838 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
KMHNKCEJ_00839 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KMHNKCEJ_00840 5.5e-161 degV S EDD domain protein, DegV family
KMHNKCEJ_00841 1.1e-89
KMHNKCEJ_00842 3.1e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
KMHNKCEJ_00843 1.2e-157 gspA M family 8
KMHNKCEJ_00844 1.1e-153 S Alpha beta hydrolase
KMHNKCEJ_00845 4.5e-94 K Acetyltransferase (GNAT) domain
KMHNKCEJ_00846 2.2e-227 XK27_08635 S UPF0210 protein
KMHNKCEJ_00847 1.2e-155 K LysR substrate binding domain protein
KMHNKCEJ_00848 2.8e-79 C Flavodoxin
KMHNKCEJ_00849 4.4e-76 yphH S Cupin domain
KMHNKCEJ_00850 6.5e-73 yeaL S UPF0756 membrane protein
KMHNKCEJ_00851 4.5e-242 EGP Major facilitator Superfamily
KMHNKCEJ_00852 5.5e-74 copY K Copper transport repressor CopY TcrY
KMHNKCEJ_00853 7.2e-245 yhdP S Transporter associated domain
KMHNKCEJ_00854 0.0 ubiB S ABC1 family
KMHNKCEJ_00855 1.1e-144 S DUF218 domain
KMHNKCEJ_00856 5.4e-68 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KMHNKCEJ_00857 1.6e-56 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KMHNKCEJ_00858 5.9e-55 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KMHNKCEJ_00859 0.0 uvrA3 L excinuclease ABC, A subunit
KMHNKCEJ_00860 4.3e-121 S SNARE associated Golgi protein
KMHNKCEJ_00861 2.3e-229 N Uncharacterized conserved protein (DUF2075)
KMHNKCEJ_00862 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KMHNKCEJ_00863 1e-13 rpmH J Ribosomal protein L34
KMHNKCEJ_00865 1.1e-39 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
KMHNKCEJ_00866 1.7e-66 V ABC transporter
KMHNKCEJ_00867 2.9e-96 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KMHNKCEJ_00869 5.7e-67 T Toxin-antitoxin system, toxin component, MazF family
KMHNKCEJ_00870 1e-37
KMHNKCEJ_00871 6.7e-07 D nuclear chromosome segregation
KMHNKCEJ_00872 0.0 snf 2.7.11.1 KL domain protein
KMHNKCEJ_00873 2e-143 ywqE 3.1.3.48 GM PHP domain protein
KMHNKCEJ_00874 2e-208 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KMHNKCEJ_00875 0.0 sbcC L Putative exonuclease SbcCD, C subunit
KMHNKCEJ_00876 2.1e-88 L nuclease
KMHNKCEJ_00877 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
KMHNKCEJ_00878 2.8e-70
KMHNKCEJ_00879 3.1e-101 fic D Fic/DOC family
KMHNKCEJ_00880 4.7e-123 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KMHNKCEJ_00881 8.3e-151 3.1.3.73 G Belongs to the phosphoglycerate mutase family
KMHNKCEJ_00882 9.3e-32
KMHNKCEJ_00883 1.3e-70
KMHNKCEJ_00884 9.5e-59
KMHNKCEJ_00885 2.1e-24
KMHNKCEJ_00886 1.4e-33 nrdH O Glutaredoxin
KMHNKCEJ_00887 1.9e-134 L Transposase
KMHNKCEJ_00888 4.8e-65 L Transposase
KMHNKCEJ_00889 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KMHNKCEJ_00890 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KMHNKCEJ_00891 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KMHNKCEJ_00892 1.7e-106 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
KMHNKCEJ_00893 2.3e-199 ykiI
KMHNKCEJ_00894 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KMHNKCEJ_00895 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KMHNKCEJ_00896 1e-110 K Bacterial regulatory proteins, tetR family
KMHNKCEJ_00897 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KMHNKCEJ_00898 4.4e-77 ctsR K Belongs to the CtsR family
KMHNKCEJ_00899 2.1e-196 adhP 1.1.1.1 C alcohol dehydrogenase
KMHNKCEJ_00900 1.8e-150 S Hydrolases of the alpha beta superfamily
KMHNKCEJ_00901 7.8e-123 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
KMHNKCEJ_00902 2.4e-95 yqeG S HAD phosphatase, family IIIA
KMHNKCEJ_00903 2.4e-217 yqeH S Ribosome biogenesis GTPase YqeH
KMHNKCEJ_00904 1.9e-47 yhbY J RNA-binding protein
KMHNKCEJ_00905 6.9e-121 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KMHNKCEJ_00906 2.8e-111 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
KMHNKCEJ_00907 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KMHNKCEJ_00908 1.1e-135 yqeM Q Methyltransferase
KMHNKCEJ_00909 6.9e-209 ylbM S Belongs to the UPF0348 family
KMHNKCEJ_00910 4.9e-99 yceD S Uncharacterized ACR, COG1399
KMHNKCEJ_00911 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KMHNKCEJ_00912 1.5e-121 K response regulator
KMHNKCEJ_00913 4.1e-278 arlS 2.7.13.3 T Histidine kinase
KMHNKCEJ_00914 4.8e-266 yjeM E Amino Acid
KMHNKCEJ_00915 1.8e-232 V MatE
KMHNKCEJ_00916 7.4e-68 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
KMHNKCEJ_00917 1.3e-168 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KMHNKCEJ_00918 8e-42 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KMHNKCEJ_00919 4.8e-145 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KMHNKCEJ_00920 5.3e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
KMHNKCEJ_00921 6.7e-59 yodB K Transcriptional regulator, HxlR family
KMHNKCEJ_00922 2.3e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KMHNKCEJ_00923 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KMHNKCEJ_00924 3.6e-114 rlpA M PFAM NLP P60 protein
KMHNKCEJ_00925 8e-117 udk 2.7.1.48 F Cytidine monophosphokinase
KMHNKCEJ_00926 5.3e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KMHNKCEJ_00927 3.1e-68 yneR S Belongs to the HesB IscA family
KMHNKCEJ_00928 0.0 S membrane
KMHNKCEJ_00929 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
KMHNKCEJ_00930 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KMHNKCEJ_00931 5.2e-101 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KMHNKCEJ_00932 3.9e-76 gluP 3.4.21.105 S Peptidase, S54 family
KMHNKCEJ_00933 2.5e-20 gluP 3.4.21.105 S Peptidase, S54 family
KMHNKCEJ_00934 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
KMHNKCEJ_00935 5.6e-183 glk 2.7.1.2 G Glucokinase
KMHNKCEJ_00936 1e-66 yqhL P Rhodanese-like protein
KMHNKCEJ_00937 5.9e-22 S Protein of unknown function (DUF3042)
KMHNKCEJ_00938 7e-175 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KMHNKCEJ_00939 6.2e-265 glnA 6.3.1.2 E glutamine synthetase
KMHNKCEJ_00940 4.5e-296 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KMHNKCEJ_00941 1.5e-92 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
KMHNKCEJ_00942 3.9e-31 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
KMHNKCEJ_00943 6.1e-42 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
KMHNKCEJ_00944 3.9e-12
KMHNKCEJ_00945 7.9e-99 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KMHNKCEJ_00946 4.8e-51 S Iron-sulfur cluster assembly protein
KMHNKCEJ_00947 9.7e-150
KMHNKCEJ_00948 3.3e-181
KMHNKCEJ_00949 1.3e-85 dut S Protein conserved in bacteria
KMHNKCEJ_00953 2.1e-103 K Transcriptional regulator
KMHNKCEJ_00954 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
KMHNKCEJ_00955 2.4e-53 ysxB J Cysteine protease Prp
KMHNKCEJ_00956 1.3e-44 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KMHNKCEJ_00957 8.9e-130 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KMHNKCEJ_00958 1.6e-199 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KMHNKCEJ_00959 1e-114 J 2'-5' RNA ligase superfamily
KMHNKCEJ_00960 2.2e-70 yqhY S Asp23 family, cell envelope-related function
KMHNKCEJ_00961 4.7e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KMHNKCEJ_00962 1.4e-148 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KMHNKCEJ_00963 6.5e-214 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KMHNKCEJ_00964 1.3e-42 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KMHNKCEJ_00965 1.4e-153 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KMHNKCEJ_00966 3.4e-149 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
KMHNKCEJ_00967 1.6e-76 argR K Regulates arginine biosynthesis genes
KMHNKCEJ_00968 5.5e-263 recN L May be involved in recombinational repair of damaged DNA
KMHNKCEJ_00969 4.2e-53
KMHNKCEJ_00970 3.5e-114 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KMHNKCEJ_00971 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KMHNKCEJ_00972 9.6e-209 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KMHNKCEJ_00973 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KMHNKCEJ_00974 6.7e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KMHNKCEJ_00975 3.1e-248 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KMHNKCEJ_00976 7.9e-129 stp 3.1.3.16 T phosphatase
KMHNKCEJ_00977 0.0 KLT serine threonine protein kinase
KMHNKCEJ_00978 8.5e-162 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KMHNKCEJ_00979 4.7e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KMHNKCEJ_00980 2.9e-119 thiN 2.7.6.2 H thiamine pyrophosphokinase
KMHNKCEJ_00981 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KMHNKCEJ_00982 4.7e-58 asp S Asp23 family, cell envelope-related function
KMHNKCEJ_00983 0.0 yloV S DAK2 domain fusion protein YloV
KMHNKCEJ_00984 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KMHNKCEJ_00985 1e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KMHNKCEJ_00986 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KMHNKCEJ_00987 1.2e-131 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KMHNKCEJ_00988 0.0 smc D Required for chromosome condensation and partitioning
KMHNKCEJ_00989 3.8e-178 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KMHNKCEJ_00990 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KMHNKCEJ_00991 1.8e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KMHNKCEJ_00992 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KMHNKCEJ_00993 5.4e-40 ylqC S Belongs to the UPF0109 family
KMHNKCEJ_00994 6.9e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KMHNKCEJ_00995 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KMHNKCEJ_00996 2.6e-261 yfnA E amino acid
KMHNKCEJ_00997 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KMHNKCEJ_00998 1e-59 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
KMHNKCEJ_00999 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KMHNKCEJ_01000 2.3e-30 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KMHNKCEJ_01001 1e-23
KMHNKCEJ_01002 5.9e-100 V VanZ like family
KMHNKCEJ_01003 7.7e-231 cycA E Amino acid permease
KMHNKCEJ_01004 2.8e-84 perR P Belongs to the Fur family
KMHNKCEJ_01005 7.9e-258 EGP Major facilitator Superfamily
KMHNKCEJ_01006 7.9e-94 tag 3.2.2.20 L glycosylase
KMHNKCEJ_01007 1.9e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KMHNKCEJ_01008 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KMHNKCEJ_01009 4.9e-41
KMHNKCEJ_01010 2.3e-301 ytgP S Polysaccharide biosynthesis protein
KMHNKCEJ_01011 2.7e-152 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KMHNKCEJ_01012 2.8e-276 pepV 3.5.1.18 E dipeptidase PepV
KMHNKCEJ_01013 7.3e-86 uspA T Belongs to the universal stress protein A family
KMHNKCEJ_01014 4.1e-176 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KMHNKCEJ_01015 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
KMHNKCEJ_01016 2.5e-112
KMHNKCEJ_01017 3.3e-186 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
KMHNKCEJ_01018 1.4e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KMHNKCEJ_01020 6.2e-66 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
KMHNKCEJ_01021 5.2e-53 metE 2.1.1.14 E Methionine synthase
KMHNKCEJ_01022 5.2e-53 ywiB S Domain of unknown function (DUF1934)
KMHNKCEJ_01023 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KMHNKCEJ_01024 6.7e-311 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KMHNKCEJ_01025 2e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KMHNKCEJ_01026 4.6e-41 rpmE2 J Ribosomal protein L31
KMHNKCEJ_01027 7.7e-236 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KMHNKCEJ_01028 3.1e-164 S Alpha/beta hydrolase of unknown function (DUF915)
KMHNKCEJ_01029 7.3e-116 srtA 3.4.22.70 M sortase family
KMHNKCEJ_01030 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
KMHNKCEJ_01031 4.2e-160 3.2.1.55 GH51 G Right handed beta helix region
KMHNKCEJ_01032 9.8e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KMHNKCEJ_01033 1.3e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
KMHNKCEJ_01034 9.2e-121 pgm3 3.1.3.73 G Belongs to the phosphoglycerate mutase family
KMHNKCEJ_01035 8e-87 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KMHNKCEJ_01036 2e-92 lemA S LemA family
KMHNKCEJ_01037 2e-158 htpX O Belongs to the peptidase M48B family
KMHNKCEJ_01038 1.9e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KMHNKCEJ_01039 3.6e-253 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KMHNKCEJ_01040 7.4e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
KMHNKCEJ_01042 6.8e-18 L the current gene model (or a revised gene model) may contain a frame shift
KMHNKCEJ_01043 1.9e-40 yeeN K transcriptional regulatory protein
KMHNKCEJ_01044 2.8e-84 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KMHNKCEJ_01045 1.7e-63 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
KMHNKCEJ_01046 7.4e-40 L Transposase
KMHNKCEJ_01047 4.7e-59 L Transposase
KMHNKCEJ_01048 3.1e-147 holA 2.7.7.7 L DNA polymerase III delta subunit
KMHNKCEJ_01049 0.0 comEC S Competence protein ComEC
KMHNKCEJ_01050 3.1e-89 comEB 3.5.4.12 F ComE operon protein 2
KMHNKCEJ_01051 5.8e-80 comEA L Competence protein ComEA
KMHNKCEJ_01052 4.3e-197 ylbL T Belongs to the peptidase S16 family
KMHNKCEJ_01053 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KMHNKCEJ_01054 1.6e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
KMHNKCEJ_01055 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
KMHNKCEJ_01056 2.7e-222 ftsW D Belongs to the SEDS family
KMHNKCEJ_01057 0.0 typA T GTP-binding protein TypA
KMHNKCEJ_01058 3.8e-134 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
KMHNKCEJ_01059 3.7e-45 yktA S Belongs to the UPF0223 family
KMHNKCEJ_01060 1.4e-275 lpdA 1.8.1.4 C Dehydrogenase
KMHNKCEJ_01061 1.7e-222 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KMHNKCEJ_01062 2.4e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
KMHNKCEJ_01063 2.8e-207 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
KMHNKCEJ_01064 1.4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KMHNKCEJ_01065 4.8e-79
KMHNKCEJ_01066 9.8e-32 ykzG S Belongs to the UPF0356 family
KMHNKCEJ_01067 6.7e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
KMHNKCEJ_01068 4.1e-89 cvfB S Protein conserved in bacteria
KMHNKCEJ_01078 2e-92 2.3.1.128 K Acetyltransferase (GNAT) domain
KMHNKCEJ_01079 6.9e-157 lmrB EGP Major facilitator Superfamily
KMHNKCEJ_01080 3.1e-31 lmrB EGP Major facilitator Superfamily
KMHNKCEJ_01081 6.5e-16 lmrB EGP Major facilitator Superfamily
KMHNKCEJ_01082 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
KMHNKCEJ_01083 7.6e-111 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KMHNKCEJ_01084 2.4e-156 sufD O Uncharacterized protein family (UPF0051)
KMHNKCEJ_01085 2e-42 lytE M LysM domain protein
KMHNKCEJ_01086 0.0 oppD EP Psort location Cytoplasmic, score
KMHNKCEJ_01087 2.6e-89 lytE M LysM domain protein
KMHNKCEJ_01088 1.5e-146 xth 3.1.11.2 L exodeoxyribonuclease III
KMHNKCEJ_01089 9.5e-236 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
KMHNKCEJ_01090 1.2e-236 preA 1.3.1.1 C 4Fe-4S dicluster domain
KMHNKCEJ_01091 1.3e-151 yeaE S Aldo keto
KMHNKCEJ_01092 2e-76 hsp O Belongs to the small heat shock protein (HSP20) family
KMHNKCEJ_01093 3.3e-283 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
KMHNKCEJ_01094 2.9e-78 S Psort location Cytoplasmic, score
KMHNKCEJ_01095 1.2e-83 S Short repeat of unknown function (DUF308)
KMHNKCEJ_01096 5.2e-56 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
KMHNKCEJ_01097 5.4e-10 XK27_02470 K LytTr DNA-binding domain protein
KMHNKCEJ_01098 1e-81 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KMHNKCEJ_01099 5.1e-81 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KMHNKCEJ_01100 4.2e-37 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KMHNKCEJ_01101 1.2e-180 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KMHNKCEJ_01103 6.6e-35 S Transglycosylase associated protein
KMHNKCEJ_01104 7e-226 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KMHNKCEJ_01105 1.5e-126 3.1.3.73 G phosphoglycerate mutase
KMHNKCEJ_01106 5.7e-115 dedA S SNARE associated Golgi protein
KMHNKCEJ_01107 0.0 helD 3.6.4.12 L DNA helicase
KMHNKCEJ_01108 1.2e-36 Q pyridine nucleotide-disulphide oxidoreductase
KMHNKCEJ_01109 1.6e-157 EG EamA-like transporter family
KMHNKCEJ_01110 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KMHNKCEJ_01111 1.7e-176 coaA 2.7.1.33 F Pantothenic acid kinase
KMHNKCEJ_01112 6.6e-218 S cog cog1373
KMHNKCEJ_01114 3.6e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KMHNKCEJ_01116 1.6e-61 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KMHNKCEJ_01117 9.2e-29 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KMHNKCEJ_01119 1.8e-31
KMHNKCEJ_01120 2.7e-109 S CAAX protease self-immunity
KMHNKCEJ_01121 1.9e-43
KMHNKCEJ_01123 1.7e-66
KMHNKCEJ_01124 2.6e-55 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KMHNKCEJ_01125 2.9e-90 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
KMHNKCEJ_01126 6.9e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
KMHNKCEJ_01127 1.8e-221 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KMHNKCEJ_01128 5.4e-104 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
KMHNKCEJ_01129 3.6e-213 folP 2.5.1.15 H dihydropteroate synthase
KMHNKCEJ_01130 6.7e-43
KMHNKCEJ_01131 4.8e-39
KMHNKCEJ_01133 4.2e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KMHNKCEJ_01134 5.3e-150 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KMHNKCEJ_01135 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
KMHNKCEJ_01136 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KMHNKCEJ_01137 9.4e-38 yheA S Belongs to the UPF0342 family
KMHNKCEJ_01138 1.8e-220 yhaO L Ser Thr phosphatase family protein
KMHNKCEJ_01139 0.0 L AAA domain
KMHNKCEJ_01140 5e-78 hsdM 2.1.1.72 V HsdM N-terminal domain
KMHNKCEJ_01141 5.5e-60 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
KMHNKCEJ_01142 6.4e-88 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
KMHNKCEJ_01143 4.1e-89 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
KMHNKCEJ_01144 3e-156 rssA S Phospholipase, patatin family
KMHNKCEJ_01145 9.4e-118 L Integrase
KMHNKCEJ_01146 2.7e-152 EG EamA-like transporter family
KMHNKCEJ_01147 9.6e-129 narI 1.7.5.1 C Nitrate reductase
KMHNKCEJ_01148 8.7e-99 narJ C nitrate reductase molybdenum cofactor assembly chaperone
KMHNKCEJ_01149 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
KMHNKCEJ_01150 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KMHNKCEJ_01151 1.8e-184 moeB 2.7.7.73, 2.7.7.80 H ThiF family
KMHNKCEJ_01152 5.2e-84 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
KMHNKCEJ_01153 8.2e-224 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
KMHNKCEJ_01154 2e-75 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
KMHNKCEJ_01155 1.2e-95 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
KMHNKCEJ_01156 5.7e-43
KMHNKCEJ_01157 5.1e-190 comP 2.7.13.3 F Sensor histidine kinase
KMHNKCEJ_01158 2.5e-92 nreC K PFAM regulatory protein LuxR
KMHNKCEJ_01159 7.8e-68 holA 2.7.7.7 L DNA polymerase III delta subunit
KMHNKCEJ_01160 4.3e-89
KMHNKCEJ_01161 1.8e-60 K Transcriptional regulator, HxlR family
KMHNKCEJ_01162 3.4e-167 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KMHNKCEJ_01163 9e-140 epsB M biosynthesis protein
KMHNKCEJ_01164 1.9e-117 ywqD 2.7.10.1 D Capsular exopolysaccharide family
KMHNKCEJ_01165 1e-103 rfbP M Bacterial sugar transferase
KMHNKCEJ_01166 7.2e-88 M family 8
KMHNKCEJ_01167 5.9e-69 rfbF GT2 S Glycosyl transferase family 2
KMHNKCEJ_01168 2.7e-48 GT2 S Glycosyltransferase, group 2 family protein
KMHNKCEJ_01169 2.5e-28 M Glycosyl transferases group 1
KMHNKCEJ_01170 8.1e-20
KMHNKCEJ_01171 7e-82 M Glycosyl transferase, family 2
KMHNKCEJ_01172 3.3e-99 S Membrane protein involved in the export of O-antigen and teichoic acid
KMHNKCEJ_01173 6.4e-162 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KMHNKCEJ_01174 4.2e-109 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KMHNKCEJ_01175 7.8e-199 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KMHNKCEJ_01176 4e-153 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KMHNKCEJ_01177 4.6e-58 ymfH S Peptidase M16
KMHNKCEJ_01178 1.4e-43 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
KMHNKCEJ_01179 6.3e-60 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KMHNKCEJ_01180 1.4e-297 mco Q Multicopper oxidase
KMHNKCEJ_01181 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KMHNKCEJ_01182 7.7e-63 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KMHNKCEJ_01183 2.7e-114 tesE Q hydratase
KMHNKCEJ_01184 1.6e-171 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KMHNKCEJ_01187 5e-28 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KMHNKCEJ_01189 7.7e-84 ybgJ 3.5.1.54 E Allophanate hydrolase subunit 1
KMHNKCEJ_01190 3.1e-107 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
KMHNKCEJ_01191 3.8e-38 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KMHNKCEJ_01192 7.8e-207 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
KMHNKCEJ_01193 7.6e-103 ycsF S LamB/YcsF family
KMHNKCEJ_01194 2.4e-178 ycsG P Natural resistance-associated macrophage protein
KMHNKCEJ_01195 3.3e-65 L Transposase
KMHNKCEJ_01196 1.9e-74 ecsA V abc transporter atp-binding protein
KMHNKCEJ_01197 5.2e-72 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
KMHNKCEJ_01198 3.7e-73 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
KMHNKCEJ_01199 5e-273 pipD E Dipeptidase
KMHNKCEJ_01200 3.6e-199 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
KMHNKCEJ_01202 1.2e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KMHNKCEJ_01203 7.5e-58
KMHNKCEJ_01204 3.1e-178 prmA J Ribosomal protein L11 methyltransferase
KMHNKCEJ_01205 6.7e-128 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KMHNKCEJ_01206 9.4e-50
KMHNKCEJ_01207 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KMHNKCEJ_01208 1.9e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KMHNKCEJ_01209 1.2e-165 yniA G Phosphotransferase enzyme family
KMHNKCEJ_01210 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KMHNKCEJ_01211 3.8e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KMHNKCEJ_01212 1.1e-262 glnPH2 P ABC transporter permease
KMHNKCEJ_01213 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KMHNKCEJ_01214 3.8e-70 yqeY S YqeY-like protein
KMHNKCEJ_01215 1.6e-169 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KMHNKCEJ_01216 5.5e-45 yitW S Pfam:DUF59
KMHNKCEJ_01217 1e-68 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
KMHNKCEJ_01218 6.4e-198 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
KMHNKCEJ_01221 0.0 3.2.1.18 GH33 M Rib/alpha-like repeat
KMHNKCEJ_01222 5.6e-15 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
KMHNKCEJ_01223 9.8e-239 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
KMHNKCEJ_01224 1.2e-129 IQ Dehydrogenase reductase
KMHNKCEJ_01225 3.2e-36
KMHNKCEJ_01226 1.8e-113 ywnB S NAD(P)H-binding
KMHNKCEJ_01227 4.5e-38 S Cytochrome b5-like Heme/Steroid binding domain
KMHNKCEJ_01228 8.3e-252 nhaC C Na H antiporter NhaC
KMHNKCEJ_01229 3.8e-182 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KMHNKCEJ_01231 3.4e-97 ydeN S Serine hydrolase
KMHNKCEJ_01232 1.6e-25 psiE S Phosphate-starvation-inducible E
KMHNKCEJ_01233 8.5e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KMHNKCEJ_01235 9.3e-178 S Aldo keto reductase
KMHNKCEJ_01236 1.7e-71 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
KMHNKCEJ_01237 0.0 L Helicase C-terminal domain protein
KMHNKCEJ_01239 2.9e-246 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
KMHNKCEJ_01240 3.7e-51 S Sugar efflux transporter for intercellular exchange
KMHNKCEJ_01241 3.9e-125
KMHNKCEJ_01242 6.9e-117 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
KMHNKCEJ_01243 0.0 cadA P P-type ATPase
KMHNKCEJ_01244 5.4e-220 5.4.2.7 G Metalloenzyme superfamily
KMHNKCEJ_01246 1.6e-35 1.6.5.2 GM NAD(P)H-binding
KMHNKCEJ_01247 1.6e-50 1.6.5.2 GM NAD(P)H-binding
KMHNKCEJ_01248 3.8e-73 K Transcriptional regulator
KMHNKCEJ_01249 6e-163 proX M ABC transporter, substrate-binding protein, QAT family
KMHNKCEJ_01250 2.4e-108 proWZ P ABC transporter permease
KMHNKCEJ_01251 6.5e-142 proV E ABC transporter, ATP-binding protein
KMHNKCEJ_01252 1.9e-102 proW P ABC transporter, permease protein
KMHNKCEJ_01253 2e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
KMHNKCEJ_01254 1.9e-63 L PFAM transposase IS200-family protein
KMHNKCEJ_01255 8.8e-215 L transposase, IS605 OrfB family
KMHNKCEJ_01256 3.9e-46 clcA P chloride
KMHNKCEJ_01257 1.9e-113 clcA P chloride
KMHNKCEJ_01258 5.5e-214 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
KMHNKCEJ_01259 3.1e-103 metI P ABC transporter permease
KMHNKCEJ_01260 4.7e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KMHNKCEJ_01261 2.8e-154 metQ1 P Belongs to the nlpA lipoprotein family
KMHNKCEJ_01262 5.8e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KMHNKCEJ_01263 1.3e-221 norA EGP Major facilitator Superfamily
KMHNKCEJ_01264 8.9e-41 1.3.5.4 S FMN binding
KMHNKCEJ_01265 2.4e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KMHNKCEJ_01266 6.4e-263 yfnA E amino acid
KMHNKCEJ_01267 3e-13 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KMHNKCEJ_01268 2.9e-232 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KMHNKCEJ_01270 2.4e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KMHNKCEJ_01271 0.0 helD 3.6.4.12 L DNA helicase
KMHNKCEJ_01272 6.3e-81 ndk 2.7.4.6 F Belongs to the NDK family
KMHNKCEJ_01273 4e-181 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
KMHNKCEJ_01274 7.7e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
KMHNKCEJ_01275 1e-165 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
KMHNKCEJ_01276 6.3e-227 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
KMHNKCEJ_01277 1.9e-175
KMHNKCEJ_01278 1.2e-129 cobB K SIR2 family
KMHNKCEJ_01280 2e-160 yunF F Protein of unknown function DUF72
KMHNKCEJ_01281 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KMHNKCEJ_01282 3.5e-154 tatD L hydrolase, TatD family
KMHNKCEJ_01283 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KMHNKCEJ_01284 9.5e-161 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KMHNKCEJ_01285 6.8e-37 veg S Biofilm formation stimulator VEG
KMHNKCEJ_01286 3.1e-161 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KMHNKCEJ_01287 6.9e-167 znuA P Belongs to the bacterial solute-binding protein 9 family
KMHNKCEJ_01288 3.2e-121 fhuC P ABC transporter
KMHNKCEJ_01289 4.7e-127 znuB U ABC 3 transport family
KMHNKCEJ_01290 6.9e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
KMHNKCEJ_01291 3.5e-239 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KMHNKCEJ_01292 4.2e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KMHNKCEJ_01293 9e-48
KMHNKCEJ_01294 2.1e-146 yxeH S hydrolase
KMHNKCEJ_01295 1e-270 ywfO S HD domain protein
KMHNKCEJ_01296 3.4e-149 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
KMHNKCEJ_01297 4.8e-35 tcyB_2 P ABC transporter (permease)
KMHNKCEJ_01299 2.7e-39
KMHNKCEJ_01300 0.0 ydaO E amino acid
KMHNKCEJ_01301 7.6e-302 ybeC E amino acid
KMHNKCEJ_01302 7.6e-80 S Aminoacyl-tRNA editing domain
KMHNKCEJ_01303 5.5e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KMHNKCEJ_01304 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KMHNKCEJ_01305 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KMHNKCEJ_01306 0.0 uup S ABC transporter, ATP-binding protein
KMHNKCEJ_01307 4.3e-183 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KMHNKCEJ_01308 2.3e-184 mtnE 2.6.1.83 E Aminotransferase
KMHNKCEJ_01309 6.2e-140 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
KMHNKCEJ_01310 4.9e-137 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KMHNKCEJ_01311 7.6e-217 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KMHNKCEJ_01312 7.5e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KMHNKCEJ_01313 2.5e-36 arbx M family 8
KMHNKCEJ_01314 1.9e-223 secY2 U SecY translocase
KMHNKCEJ_01315 1.4e-284 asp1 S Accessory Sec system protein Asp1
KMHNKCEJ_01316 3.3e-305 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
KMHNKCEJ_01317 2.2e-16 asp3 S Accessory Sec secretory system ASP3
KMHNKCEJ_01318 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KMHNKCEJ_01320 2.5e-283 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KMHNKCEJ_01321 4.2e-261 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
KMHNKCEJ_01322 7.8e-22 L Phage integrase, N-terminal SAM-like domain
KMHNKCEJ_01323 1.3e-224 oxlT P Major Facilitator Superfamily
KMHNKCEJ_01324 3e-159 spoU 2.1.1.185 J Methyltransferase
KMHNKCEJ_01325 1.9e-90 ywlG S Belongs to the UPF0340 family
KMHNKCEJ_01326 3.4e-151 ansA 3.5.1.1 EJ L-asparaginase, type I
KMHNKCEJ_01327 6e-195 aadAT EK Aminotransferase, class I
KMHNKCEJ_01328 3e-165 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KMHNKCEJ_01330 2.3e-28
KMHNKCEJ_01331 1.4e-140 D CobQ CobB MinD ParA nucleotide binding domain protein
KMHNKCEJ_01335 1e-60 L Resolvase, N terminal domain
KMHNKCEJ_01336 1e-33 S Phage derived protein Gp49-like (DUF891)
KMHNKCEJ_01337 7.1e-25 K Helix-turn-helix domain
KMHNKCEJ_01338 9.2e-40 S Plasmid replication protein
KMHNKCEJ_01339 9.4e-71 pre D plasmid recombination enzyme
KMHNKCEJ_01340 6e-93 cca 2.7.7.19, 2.7.7.72 J Aminoglycoside-2''-adenylyltransferase
KMHNKCEJ_01341 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
KMHNKCEJ_01342 8.7e-34 copZ C Heavy-metal-associated domain
KMHNKCEJ_01343 5.7e-92 dps P Belongs to the Dps family
KMHNKCEJ_01344 6.8e-113 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
KMHNKCEJ_01345 1.7e-16 ung2 3.2.2.27 L Uracil-DNA glycosylase
KMHNKCEJ_01346 1.5e-82 ung2 3.2.2.27 L Uracil-DNA glycosylase
KMHNKCEJ_01347 1.8e-61 5.1.1.13 M Asp/Glu/Hydantoin racemase
KMHNKCEJ_01348 7.5e-22 5.1.1.13 M Asp/Glu/Hydantoin racemase
KMHNKCEJ_01349 5.4e-148 L Recombinase
KMHNKCEJ_01350 2.4e-110 L Recombinase zinc beta ribbon domain
KMHNKCEJ_01351 1.3e-68 L Recombinase zinc beta ribbon domain
KMHNKCEJ_01352 8.2e-19
KMHNKCEJ_01353 5.4e-55 S Bacteriophage holin family
KMHNKCEJ_01354 6.5e-55 S Phage head-tail joining protein
KMHNKCEJ_01355 4.6e-39 S Phage gp6-like head-tail connector protein
KMHNKCEJ_01356 2.7e-183 S Phage capsid family
KMHNKCEJ_01357 1.2e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KMHNKCEJ_01358 1.1e-127 3.6.1.13, 3.6.1.55 F NUDIX domain
KMHNKCEJ_01359 1e-257 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KMHNKCEJ_01360 1.2e-102 pncA Q Isochorismatase family
KMHNKCEJ_01361 4.8e-93 K Acetyltransferase (GNAT) family
KMHNKCEJ_01362 8.5e-12
KMHNKCEJ_01363 4.9e-64 yhjX P Major Facilitator Superfamily
KMHNKCEJ_01364 9.3e-119 ybhL S Belongs to the BI1 family
KMHNKCEJ_01365 2.1e-79 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
KMHNKCEJ_01366 5.7e-194 S Protein of unknown function (DUF3114)
KMHNKCEJ_01367 1e-295 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
KMHNKCEJ_01368 1.5e-164 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KMHNKCEJ_01369 1.1e-104 yvdD 3.2.2.10 S Belongs to the LOG family
KMHNKCEJ_01370 9.1e-62 S Domain of unknown function (DUF4828)
KMHNKCEJ_01371 5.9e-191 mocA S Oxidoreductase
KMHNKCEJ_01372 2.5e-231 yfmL L DEAD DEAH box helicase
KMHNKCEJ_01374 9e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KMHNKCEJ_01375 3.8e-33
KMHNKCEJ_01376 7.5e-16
KMHNKCEJ_01377 1.3e-67 gtcA S Teichoic acid glycosylation protein
KMHNKCEJ_01378 1.4e-78 fld C Flavodoxin
KMHNKCEJ_01379 6.5e-167 map 3.4.11.18 E Methionine Aminopeptidase
KMHNKCEJ_01380 2.6e-97 2.3.1.128 K acetyltransferase
KMHNKCEJ_01381 2.4e-192
KMHNKCEJ_01383 3.4e-35 L Transposase
KMHNKCEJ_01384 8.6e-120 L Transposase
KMHNKCEJ_01385 8.1e-131 K Transcriptional regulatory protein, C-terminal domain protein
KMHNKCEJ_01386 5.6e-158 pstS P Phosphate
KMHNKCEJ_01387 9.5e-153 pstC P probably responsible for the translocation of the substrate across the membrane
KMHNKCEJ_01388 5.9e-155 pstA P Phosphate transport system permease protein PstA
KMHNKCEJ_01389 3.1e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KMHNKCEJ_01390 1.9e-124 phoU P Plays a role in the regulation of phosphate uptake
KMHNKCEJ_01391 2.1e-141
KMHNKCEJ_01393 2.5e-242 ydaM M Glycosyl transferase
KMHNKCEJ_01394 3.2e-222 G Glycosyl hydrolases family 8
KMHNKCEJ_01395 2.3e-139 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
KMHNKCEJ_01396 8.9e-253 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KMHNKCEJ_01397 4.7e-213 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KMHNKCEJ_01398 4.3e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KMHNKCEJ_01399 8.1e-101 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KMHNKCEJ_01400 5.8e-172 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
KMHNKCEJ_01401 3.4e-187 thrC 4.2.3.1 E Threonine synthase
KMHNKCEJ_01402 2.7e-24 K helix_turn_helix, arabinose operon control protein
KMHNKCEJ_01403 2.7e-11 mocA S Oxidoreductase
KMHNKCEJ_01404 4.5e-129 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
KMHNKCEJ_01405 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KMHNKCEJ_01406 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
KMHNKCEJ_01408 6.6e-174 K AI-2E family transporter
KMHNKCEJ_01409 1.8e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KMHNKCEJ_01410 1.5e-36 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KMHNKCEJ_01411 3.1e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KMHNKCEJ_01412 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KMHNKCEJ_01413 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KMHNKCEJ_01414 6.2e-196 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KMHNKCEJ_01415 8e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KMHNKCEJ_01416 4.6e-296 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KMHNKCEJ_01417 2.4e-242 purD 6.3.4.13 F Belongs to the GARS family
KMHNKCEJ_01418 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KMHNKCEJ_01419 1e-166
KMHNKCEJ_01420 5.4e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KMHNKCEJ_01421 1e-209 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KMHNKCEJ_01422 4.2e-181 ccpA K catabolite control protein A
KMHNKCEJ_01423 1.8e-132
KMHNKCEJ_01424 5.9e-132 yebC K Transcriptional regulatory protein
KMHNKCEJ_01425 4.9e-179 comGA NU Type II IV secretion system protein
KMHNKCEJ_01426 5.1e-182 comGB NU type II secretion system
KMHNKCEJ_01427 7.1e-47 comGC U competence protein ComGC
KMHNKCEJ_01428 3.4e-79 NU general secretion pathway protein
KMHNKCEJ_01429 3.2e-41
KMHNKCEJ_01430 1.2e-68
KMHNKCEJ_01432 2.1e-143 ytxK 2.1.1.72 L N-6 DNA Methylase
KMHNKCEJ_01433 1.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KMHNKCEJ_01434 1.6e-111 S Calcineurin-like phosphoesterase
KMHNKCEJ_01435 6.6e-93 yutD S Protein of unknown function (DUF1027)
KMHNKCEJ_01436 9.4e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KMHNKCEJ_01437 3.3e-102 S Protein of unknown function (DUF1461)
KMHNKCEJ_01438 4.7e-109 dedA S SNARE-like domain protein
KMHNKCEJ_01444 9e-113 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
KMHNKCEJ_01445 3.3e-275 lysP E amino acid
KMHNKCEJ_01446 4.7e-08 2.3.1.128 J Acetyltransferase (GNAT) domain
KMHNKCEJ_01447 1.5e-118 lssY 3.6.1.27 I phosphatase
KMHNKCEJ_01448 1e-81 S Threonine/Serine exporter, ThrE
KMHNKCEJ_01449 4.4e-127 thrE S Putative threonine/serine exporter
KMHNKCEJ_01450 1e-30 cspC K Cold shock protein
KMHNKCEJ_01451 1.6e-123 sirR K iron dependent repressor
KMHNKCEJ_01452 5.5e-164 czcD P cation diffusion facilitator family transporter
KMHNKCEJ_01453 7.2e-116 S membrane
KMHNKCEJ_01454 4.2e-108 S VIT family
KMHNKCEJ_01455 5.5e-83 usp1 T Belongs to the universal stress protein A family
KMHNKCEJ_01456 4.1e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KMHNKCEJ_01457 3.3e-152 glnH ET ABC transporter
KMHNKCEJ_01458 2.4e-110 gluC P ABC transporter permease
KMHNKCEJ_01459 3.6e-109 glnP P ABC transporter permease
KMHNKCEJ_01460 7.5e-57 ltrA S Bacterial low temperature requirement A protein (LtrA)
KMHNKCEJ_01461 3.4e-43 ltrA S Bacterial low temperature requirement A protein (LtrA)
KMHNKCEJ_01462 1.6e-79 uspA T universal stress protein
KMHNKCEJ_01463 1.4e-78 K AsnC family
KMHNKCEJ_01464 1.6e-228 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KMHNKCEJ_01465 3e-97 dedA 3.1.3.1 S SNARE associated Golgi protein
KMHNKCEJ_01466 7.7e-180 galR K Transcriptional regulator
KMHNKCEJ_01467 1.5e-277 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KMHNKCEJ_01468 1.1e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KMHNKCEJ_01469 2.1e-177 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
KMHNKCEJ_01470 1.9e-144 ptp3 3.1.3.48 T Tyrosine phosphatase family
KMHNKCEJ_01471 5.3e-92 yxkA S Phosphatidylethanolamine-binding protein
KMHNKCEJ_01472 9.1e-36
KMHNKCEJ_01473 2e-52
KMHNKCEJ_01474 1.1e-201
KMHNKCEJ_01475 1.1e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KMHNKCEJ_01476 2.9e-134 pnuC H nicotinamide mononucleotide transporter
KMHNKCEJ_01477 3.9e-156 ytbE 1.1.1.346 S Aldo keto reductase
KMHNKCEJ_01478 7.4e-132 K response regulator
KMHNKCEJ_01479 2.8e-182 T PhoQ Sensor
KMHNKCEJ_01480 7.1e-133 macB2 V ABC transporter, ATP-binding protein
KMHNKCEJ_01481 0.0 ysaB V FtsX-like permease family
KMHNKCEJ_01482 7.2e-155 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
KMHNKCEJ_01483 4.8e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KMHNKCEJ_01484 6.2e-10 K helix_turn_helix, mercury resistance
KMHNKCEJ_01485 7.1e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KMHNKCEJ_01486 4.9e-194 EGP Major facilitator Superfamily
KMHNKCEJ_01487 3.9e-87 ymdB S Macro domain protein
KMHNKCEJ_01488 3e-99 K Helix-turn-helix XRE-family like proteins
KMHNKCEJ_01489 0.0 pepO 3.4.24.71 O Peptidase family M13
KMHNKCEJ_01490 1.9e-46
KMHNKCEJ_01491 2.1e-230 S Putative metallopeptidase domain
KMHNKCEJ_01492 4.4e-203 3.1.3.1 S associated with various cellular activities
KMHNKCEJ_01493 5.2e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
KMHNKCEJ_01494 5.9e-64 yeaO S Protein of unknown function, DUF488
KMHNKCEJ_01496 1.5e-118 yrkL S Flavodoxin-like fold
KMHNKCEJ_01497 1.5e-52
KMHNKCEJ_01498 5.3e-16 S Domain of unknown function (DUF4767)
KMHNKCEJ_01499 4.2e-29 3.6.4.12 S PD-(D/E)XK nuclease family transposase
KMHNKCEJ_01500 9.1e-49
KMHNKCEJ_01501 8.9e-206 nrnB S DHHA1 domain
KMHNKCEJ_01502 6.2e-227 S Uncharacterized protein conserved in bacteria (DUF2325)
KMHNKCEJ_01503 1.2e-247 brnQ U Component of the transport system for branched-chain amino acids
KMHNKCEJ_01504 1.1e-104 NU mannosyl-glycoprotein
KMHNKCEJ_01505 5e-142 S Putative ABC-transporter type IV
KMHNKCEJ_01506 7.1e-273 S ABC transporter, ATP-binding protein
KMHNKCEJ_01507 6.4e-08 S HTH domain
KMHNKCEJ_01508 2.4e-34 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
KMHNKCEJ_01509 4.3e-181 arsB 1.20.4.1 P Sodium Bile acid symporter family
KMHNKCEJ_01510 8.2e-72 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KMHNKCEJ_01511 6.1e-55 cadX K Bacterial regulatory protein, arsR family
KMHNKCEJ_01512 6.2e-95 cadD P Cadmium resistance transporter
KMHNKCEJ_01513 1.1e-13 K Transcriptional
KMHNKCEJ_01514 4.5e-51 L Integrase
KMHNKCEJ_01515 1e-28 WQ51_00220 K Helix-turn-helix domain
KMHNKCEJ_01516 6e-98 S Protein of unknown function (DUF3278)
KMHNKCEJ_01517 1.7e-73 M PFAM NLP P60 protein
KMHNKCEJ_01518 4.1e-181 ABC-SBP S ABC transporter
KMHNKCEJ_01519 1.1e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
KMHNKCEJ_01520 4.8e-137 XK27_08845 S ABC transporter, ATP-binding protein
KMHNKCEJ_01521 7.4e-95 P Cadmium resistance transporter
KMHNKCEJ_01522 9.9e-55 K Transcriptional regulator, ArsR family
KMHNKCEJ_01523 4.3e-234 mepA V MATE efflux family protein
KMHNKCEJ_01524 1.5e-55 trxA O Belongs to the thioredoxin family
KMHNKCEJ_01525 7.3e-130 terC P membrane
KMHNKCEJ_01526 1.8e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KMHNKCEJ_01527 2.8e-168 corA P CorA-like Mg2+ transporter protein
KMHNKCEJ_01528 4.3e-280 pipD E Dipeptidase
KMHNKCEJ_01529 1.4e-240 pbuX F xanthine permease
KMHNKCEJ_01530 2.7e-250 nhaC C Na H antiporter NhaC
KMHNKCEJ_01531 2.5e-184 S C4-dicarboxylate anaerobic carrier
KMHNKCEJ_01532 6.7e-67 S C4-dicarboxylate anaerobic carrier
KMHNKCEJ_01533 1.3e-70 IQ Enoyl-(Acyl carrier protein) reductase
KMHNKCEJ_01534 2.8e-20 K Bacterial transcriptional regulator
KMHNKCEJ_01536 8e-125 pgm3 3.1.3.73 G phosphoglycerate mutase family
KMHNKCEJ_01537 1.2e-39
KMHNKCEJ_01538 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KMHNKCEJ_01539 8.4e-207 gldA 1.1.1.6 C dehydrogenase
KMHNKCEJ_01540 8e-182 iunH2 3.2.2.1 F nucleoside hydrolase
KMHNKCEJ_01541 9.8e-183 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
KMHNKCEJ_01542 1.3e-34 3.6.4.12 S PD-(D/E)XK nuclease family transposase
KMHNKCEJ_01543 7e-46 3.6.4.12 S PD-(D/E)XK nuclease family transposase
KMHNKCEJ_01544 6.8e-36 3.6.4.12 S PD-(D/E)XK nuclease family transposase
KMHNKCEJ_01545 1.3e-114 gph 3.1.3.18 S HAD hydrolase, family IA, variant
KMHNKCEJ_01546 2.2e-177 yagE E amino acid
KMHNKCEJ_01547 9.2e-23 yagE E amino acid
KMHNKCEJ_01548 3.4e-85 dps P Belongs to the Dps family
KMHNKCEJ_01549 0.0 pacL 3.6.3.8 P P-type ATPase
KMHNKCEJ_01550 5.6e-177 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
KMHNKCEJ_01551 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KMHNKCEJ_01552 1.3e-10 glsA 3.5.1.2 E Belongs to the glutaminase family
KMHNKCEJ_01553 4.8e-57 ytzB S Small secreted protein
KMHNKCEJ_01554 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KMHNKCEJ_01555 2.9e-119 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KMHNKCEJ_01556 4.9e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KMHNKCEJ_01557 1.9e-119 ybhL S Belongs to the BI1 family
KMHNKCEJ_01558 9.2e-116 yoaK S Protein of unknown function (DUF1275)
KMHNKCEJ_01559 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KMHNKCEJ_01560 4.1e-158 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KMHNKCEJ_01561 1.7e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KMHNKCEJ_01562 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KMHNKCEJ_01563 1e-222 dnaB L replication initiation and membrane attachment
KMHNKCEJ_01564 4.3e-172 dnaI L Primosomal protein DnaI
KMHNKCEJ_01565 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KMHNKCEJ_01566 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KMHNKCEJ_01567 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KMHNKCEJ_01572 2.2e-129 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
KMHNKCEJ_01573 2e-135 accA 2.1.3.15, 6.4.1.2 I alpha subunit
KMHNKCEJ_01574 2.5e-142 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KMHNKCEJ_01575 4.8e-257 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
KMHNKCEJ_01576 8.6e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KMHNKCEJ_01577 5.8e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KMHNKCEJ_01578 2.5e-220 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KMHNKCEJ_01579 4.5e-124 IQ reductase
KMHNKCEJ_01580 2.9e-152 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
KMHNKCEJ_01581 1.4e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KMHNKCEJ_01582 6e-169 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KMHNKCEJ_01583 1.2e-76 marR K Transcriptional regulator, MarR family
KMHNKCEJ_01584 1.1e-69 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KMHNKCEJ_01586 4.7e-199 xerS L Belongs to the 'phage' integrase family
KMHNKCEJ_01587 2.5e-104 L Helix-turn-helix domain
KMHNKCEJ_01588 9.3e-29 MA20_14895 S Conserved hypothetical protein 698
KMHNKCEJ_01593 2.8e-10 L Resolvase, N terminal domain
KMHNKCEJ_01594 3.4e-57 L Resolvase, N terminal domain
KMHNKCEJ_01596 3.3e-09
KMHNKCEJ_01598 3.6e-20 S DNA binding domain, excisionase family
KMHNKCEJ_01599 1.5e-196 L Belongs to the 'phage' integrase family
KMHNKCEJ_01600 1.1e-84
KMHNKCEJ_01601 9.8e-172
KMHNKCEJ_01602 5.6e-74
KMHNKCEJ_01603 1.3e-137 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KMHNKCEJ_01604 7.1e-147 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KMHNKCEJ_01605 3.6e-117 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
KMHNKCEJ_01606 5.7e-228 clcA_2 P Chloride transporter, ClC family
KMHNKCEJ_01607 4.4e-129 L PFAM transposase IS116 IS110 IS902
KMHNKCEJ_01608 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
KMHNKCEJ_01609 9.3e-110 lssY 3.6.1.27 I Acid phosphatase homologues
KMHNKCEJ_01610 5.9e-160 L Transposase IS66 family
KMHNKCEJ_01611 2.3e-41 XK27_01125 L PFAM IS66 Orf2 family protein
KMHNKCEJ_01612 9.4e-193 L Transposase IS66 family
KMHNKCEJ_01613 3.4e-53 XK27_01125 L PFAM IS66 Orf2 family protein
KMHNKCEJ_01615 2.8e-86 tra L Transposase and inactivated derivatives, IS30 family
KMHNKCEJ_01616 2.3e-82 M transferase activity, transferring glycosyl groups
KMHNKCEJ_01617 3e-38 M transferase activity, transferring glycosyl groups
KMHNKCEJ_01618 3.8e-18 nss M transferase activity, transferring glycosyl groups
KMHNKCEJ_01619 1.5e-45 nss M transferase activity, transferring glycosyl groups
KMHNKCEJ_01620 4.2e-76 arbx M family 8
KMHNKCEJ_01621 3.2e-52 M Glycosyltransferase like family 2
KMHNKCEJ_01622 6.2e-48 M Glycosyltransferase like family 2
KMHNKCEJ_01623 3.6e-12 M Glycosyltransferase like family 2
KMHNKCEJ_01624 4.9e-46 M family 8
KMHNKCEJ_01625 4.5e-20 S Psort location Cytoplasmic, score 8.87
KMHNKCEJ_01627 2e-61 soj D AAA domain
KMHNKCEJ_01628 5.3e-10
KMHNKCEJ_01630 0.0 LV site-specific DNA-methyltransferase (adenine-specific) activity
KMHNKCEJ_01632 5.7e-90 L Integrase
KMHNKCEJ_01633 8.1e-79 L An automated process has identified a potential problem with this gene model
KMHNKCEJ_01636 1.8e-284 S Protein of unknown function DUF262
KMHNKCEJ_01637 0.0 L Type III restriction enzyme, res subunit
KMHNKCEJ_01638 7.6e-104 L Type III restriction enzyme, res subunit
KMHNKCEJ_01639 6.5e-24 2.1.1.72, 3.1.21.4 L Eco57I restriction-modification methylase
KMHNKCEJ_01640 7.7e-72 2.1.1.72, 3.1.21.4 L restriction endonuclease
KMHNKCEJ_01641 7e-77 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
KMHNKCEJ_01643 2.7e-255 G PTS system Galactitol-specific IIC component
KMHNKCEJ_01644 9.3e-108 1.6.5.5 C Zinc-binding dehydrogenase
KMHNKCEJ_01645 1.5e-49 1.6.5.5 C Zinc-binding dehydrogenase
KMHNKCEJ_01646 8.5e-159
KMHNKCEJ_01647 1e-72 K Transcriptional regulator
KMHNKCEJ_01648 1e-171 D Alpha beta
KMHNKCEJ_01649 1.1e-51 ypaA S Protein of unknown function (DUF1304)
KMHNKCEJ_01650 0.0 yjcE P Sodium proton antiporter
KMHNKCEJ_01651 1.6e-52 yvlA
KMHNKCEJ_01652 6.6e-111 P Cobalt transport protein
KMHNKCEJ_01653 4.9e-249 cbiO1 S ABC transporter, ATP-binding protein
KMHNKCEJ_01654 1.3e-96 S ABC-type cobalt transport system, permease component
KMHNKCEJ_01655 1.2e-95 L Integrase
KMHNKCEJ_01656 2e-53 S Phage derived protein Gp49-like (DUF891)
KMHNKCEJ_01657 9.1e-38 K Helix-turn-helix domain
KMHNKCEJ_01659 6.2e-219
KMHNKCEJ_01661 1.9e-107 K Cro/C1-type HTH DNA-binding domain
KMHNKCEJ_01662 1.7e-13 L Transposase and inactivated derivatives
KMHNKCEJ_01663 5.4e-158 L HTH-like domain
KMHNKCEJ_01664 7.4e-169 bcrA V ABC transporter
KMHNKCEJ_01665 9.8e-127 S ABC-2 family transporter protein
KMHNKCEJ_01666 1.8e-110 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
KMHNKCEJ_01667 1.1e-95 K Acetyltransferase (GNAT) domain
KMHNKCEJ_01668 5e-295 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
KMHNKCEJ_01669 3.1e-232 gntT EG Gluconate
KMHNKCEJ_01670 4.9e-182 K Transcriptional regulator, LacI family
KMHNKCEJ_01671 4.1e-289 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
KMHNKCEJ_01672 1.1e-92
KMHNKCEJ_01673 3.6e-25
KMHNKCEJ_01674 1.8e-60 asp S Asp23 family, cell envelope-related function
KMHNKCEJ_01675 1.2e-85 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
KMHNKCEJ_01677 3e-48
KMHNKCEJ_01678 2.7e-67 yqkB S Belongs to the HesB IscA family
KMHNKCEJ_01679 3.9e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
KMHNKCEJ_01680 8.1e-79 F NUDIX domain
KMHNKCEJ_01681 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KMHNKCEJ_01682 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KMHNKCEJ_01683 1.2e-104 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KMHNKCEJ_01684 1.4e-164 lacX 5.1.3.3 G Aldose 1-epimerase
KMHNKCEJ_01685 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KMHNKCEJ_01686 2.7e-160 dprA LU DNA protecting protein DprA
KMHNKCEJ_01687 7.9e-140 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KMHNKCEJ_01688 3.5e-160 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KMHNKCEJ_01689 4.4e-35 yozE S Belongs to the UPF0346 family
KMHNKCEJ_01690 1.5e-106 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
KMHNKCEJ_01691 2.8e-168 ypmR E lipolytic protein G-D-S-L family
KMHNKCEJ_01692 6.4e-151 DegV S EDD domain protein, DegV family
KMHNKCEJ_01693 1.9e-110 hlyIII S protein, hemolysin III
KMHNKCEJ_01694 9.6e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KMHNKCEJ_01695 7.2e-191 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KMHNKCEJ_01696 0.0 yfmR S ABC transporter, ATP-binding protein
KMHNKCEJ_01697 8.2e-224 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KMHNKCEJ_01698 1.4e-234 S Tetratricopeptide repeat protein
KMHNKCEJ_01699 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KMHNKCEJ_01700 1.2e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KMHNKCEJ_01701 1.5e-204 rpsA 1.17.7.4 J Ribosomal protein S1
KMHNKCEJ_01702 7.6e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KMHNKCEJ_01703 9.7e-25 M Lysin motif
KMHNKCEJ_01704 8.4e-268 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
KMHNKCEJ_01705 7.5e-194 ypbB 5.1.3.1 S Helix-turn-helix domain
KMHNKCEJ_01706 5.5e-101 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KMHNKCEJ_01707 5.9e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KMHNKCEJ_01708 2.9e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KMHNKCEJ_01709 9.3e-136 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KMHNKCEJ_01710 2.8e-63 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KMHNKCEJ_01711 2.9e-162 xerD D recombinase XerD
KMHNKCEJ_01712 9.3e-169 cvfB S S1 domain
KMHNKCEJ_01713 1.4e-270 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KMHNKCEJ_01714 0.0 dnaE 2.7.7.7 L DNA polymerase
KMHNKCEJ_01715 2e-29 S Protein of unknown function (DUF2929)
KMHNKCEJ_01716 1.1e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KMHNKCEJ_01717 6.5e-156 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KMHNKCEJ_01718 6.2e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
KMHNKCEJ_01719 2.4e-220 patA 2.6.1.1 E Aminotransferase
KMHNKCEJ_01720 7.7e-208 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KMHNKCEJ_01721 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KMHNKCEJ_01722 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KMHNKCEJ_01723 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KMHNKCEJ_01724 5.8e-146 recO L Involved in DNA repair and RecF pathway recombination
KMHNKCEJ_01725 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KMHNKCEJ_01726 4.7e-59 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KMHNKCEJ_01727 3.3e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KMHNKCEJ_01728 7.9e-180 phoH T phosphate starvation-inducible protein PhoH
KMHNKCEJ_01729 5.4e-170 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KMHNKCEJ_01730 3.8e-83 bioY S BioY family
KMHNKCEJ_01731 7.8e-263 argH 4.3.2.1 E argininosuccinate lyase
KMHNKCEJ_01732 1.7e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KMHNKCEJ_01733 1.4e-186 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KMHNKCEJ_01734 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KMHNKCEJ_01736 4e-164 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
KMHNKCEJ_01737 1.9e-122 S Domain of unknown function (DUF4811)
KMHNKCEJ_01738 2.1e-269 lmrB EGP Major facilitator Superfamily
KMHNKCEJ_01739 3.1e-72 merR K MerR HTH family regulatory protein
KMHNKCEJ_01740 2.9e-57
KMHNKCEJ_01741 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KMHNKCEJ_01742 1.6e-183 S CAAX protease self-immunity
KMHNKCEJ_01743 5.7e-231 EGP Sugar (and other) transporter
KMHNKCEJ_01744 1.8e-254 yfnA E Amino Acid
KMHNKCEJ_01745 6.9e-74 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
KMHNKCEJ_01746 1.5e-98 gmk2 2.7.4.8 F Guanylate kinase
KMHNKCEJ_01747 2.1e-81 zur P Belongs to the Fur family
KMHNKCEJ_01748 4e-17 3.2.1.14 GH18
KMHNKCEJ_01749 2.7e-149
KMHNKCEJ_01750 3.4e-39 pspC KT positive regulation of macromolecule biosynthetic process
KMHNKCEJ_01751 1.6e-94 K Transcriptional regulator (TetR family)
KMHNKCEJ_01752 3.5e-233 V domain protein
KMHNKCEJ_01753 3.6e-260 S Putative peptidoglycan binding domain
KMHNKCEJ_01754 3.9e-108 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
KMHNKCEJ_01755 1.6e-67
KMHNKCEJ_01756 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
KMHNKCEJ_01757 2.6e-214 yttB EGP Major facilitator Superfamily
KMHNKCEJ_01758 8.2e-103
KMHNKCEJ_01759 3.9e-24
KMHNKCEJ_01760 1.8e-173 scrR K Transcriptional regulator, LacI family
KMHNKCEJ_01761 3.7e-205 amtB P ammonium transporter
KMHNKCEJ_01762 2e-247 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
KMHNKCEJ_01763 8.6e-84 yvbK 3.1.3.25 K GNAT family
KMHNKCEJ_01764 9.6e-92
KMHNKCEJ_01765 4.1e-121 pnb C nitroreductase
KMHNKCEJ_01766 3.1e-75 ogt 2.1.1.63 L Methyltransferase
KMHNKCEJ_01767 1.6e-155 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
KMHNKCEJ_01768 1.3e-65 S Protein of unknown function (DUF3021)
KMHNKCEJ_01769 8.6e-75 K LytTr DNA-binding domain
KMHNKCEJ_01770 2.6e-137 L Integrase core domain
KMHNKCEJ_01771 3.7e-193 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KMHNKCEJ_01772 2.3e-101 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
KMHNKCEJ_01773 1.2e-126 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
KMHNKCEJ_01774 6.8e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KMHNKCEJ_01775 8.4e-171 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
KMHNKCEJ_01776 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KMHNKCEJ_01777 9.7e-283 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
KMHNKCEJ_01778 1.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
KMHNKCEJ_01779 1e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KMHNKCEJ_01780 3e-119 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KMHNKCEJ_01781 9.5e-197 coiA 3.6.4.12 S Competence protein
KMHNKCEJ_01782 1.6e-260 pipD E Dipeptidase
KMHNKCEJ_01783 5.8e-112 yjbH Q Thioredoxin
KMHNKCEJ_01784 2.3e-111 yjbM 2.7.6.5 S RelA SpoT domain protein
KMHNKCEJ_01785 8.6e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KMHNKCEJ_01786 1.6e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
KMHNKCEJ_01787 2.4e-192 V Beta-lactamase
KMHNKCEJ_01788 1.6e-94 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KMHNKCEJ_01789 9.2e-104 yhiD S MgtC family
KMHNKCEJ_01790 3.5e-117 S GyrI-like small molecule binding domain
KMHNKCEJ_01792 2.8e-109 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
KMHNKCEJ_01793 3.2e-50 azlD E Branched-chain amino acid transport
KMHNKCEJ_01794 4.1e-119 azlC E azaleucine resistance protein AzlC
KMHNKCEJ_01795 1.7e-257 K Aminotransferase class I and II
KMHNKCEJ_01796 1e-218 S amidohydrolase
KMHNKCEJ_01797 5.3e-176 fecB P Periplasmic binding protein
KMHNKCEJ_01798 5e-134 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
KMHNKCEJ_01799 4.6e-129 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMHNKCEJ_01800 2.5e-77 S Flavodoxin
KMHNKCEJ_01801 3.5e-62 moaE 2.8.1.12 H MoaE protein
KMHNKCEJ_01802 3.9e-32 moaD 2.8.1.12 H ThiS family
KMHNKCEJ_01803 1.1e-129 narK P Transporter, major facilitator family protein
KMHNKCEJ_01804 1e-60 narK P Transporter, major facilitator family protein
KMHNKCEJ_01805 5.1e-154 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
KMHNKCEJ_01806 1.4e-181
KMHNKCEJ_01807 1.6e-18
KMHNKCEJ_01808 2.4e-17 nreC K PFAM regulatory protein LuxR
KMHNKCEJ_01809 1.3e-73 M Glycosyltransferase like family 2
KMHNKCEJ_01810 5e-159 M family 8
KMHNKCEJ_01811 3.5e-188 nss M transferase activity, transferring glycosyl groups
KMHNKCEJ_01812 4.9e-77 S glycosyl transferase family 2
KMHNKCEJ_01813 8.1e-88 M family 8
KMHNKCEJ_01814 1.5e-141 M Glycosyltransferase like family 2
KMHNKCEJ_01815 9.8e-133 2.7.8.12 GT2 M Glycosyltransferase like family 2
KMHNKCEJ_01816 3.9e-159 mleR K LysR family
KMHNKCEJ_01817 3.6e-252 yjjP S Putative threonine/serine exporter
KMHNKCEJ_01818 1e-116 ung2 3.2.2.27 L Uracil-DNA glycosylase
KMHNKCEJ_01819 6.5e-271 emrY EGP Major facilitator Superfamily
KMHNKCEJ_01820 9.4e-186 I Alpha beta
KMHNKCEJ_01821 9.8e-103 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
KMHNKCEJ_01822 3.8e-96 ltrA_1 L Reverse transcriptase (RNA-dependent DNA polymerase)
KMHNKCEJ_01823 1.7e-176 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KMHNKCEJ_01824 5.9e-201 XK27_09615 S reductase
KMHNKCEJ_01825 2.1e-100 nqr 1.5.1.36 S reductase
KMHNKCEJ_01827 5.9e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KMHNKCEJ_01828 1.1e-173 K Transcriptional regulator, LacI family
KMHNKCEJ_01829 6.1e-260 G Major Facilitator
KMHNKCEJ_01830 4.8e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KMHNKCEJ_01831 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
KMHNKCEJ_01832 8.3e-265 G Major Facilitator
KMHNKCEJ_01833 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
KMHNKCEJ_01834 1.1e-271 M protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
KMHNKCEJ_01835 1.4e-270 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
KMHNKCEJ_01836 1.5e-267 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
KMHNKCEJ_01837 8.3e-72
KMHNKCEJ_01838 3.4e-74 K Transcriptional regulator, TetR family
KMHNKCEJ_01839 2.1e-12 K Transcriptional regulator, TetR family
KMHNKCEJ_01840 1.1e-13 steT_1 E amino acid
KMHNKCEJ_01842 1.4e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KMHNKCEJ_01843 6.9e-83
KMHNKCEJ_01844 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KMHNKCEJ_01845 9.9e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KMHNKCEJ_01846 1.7e-262 nox C NADH oxidase
KMHNKCEJ_01847 3e-87 hmpT S ECF-type riboflavin transporter, S component
KMHNKCEJ_01848 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
KMHNKCEJ_01849 5.9e-168 yvgN C Aldo keto reductase
KMHNKCEJ_01850 6.6e-136 puuD S peptidase C26
KMHNKCEJ_01851 4.7e-257 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
KMHNKCEJ_01852 1.4e-215 yfeO P Voltage gated chloride channel
KMHNKCEJ_01853 3.1e-226 sptS 2.7.13.3 T Histidine kinase
KMHNKCEJ_01854 2.1e-117 K response regulator
KMHNKCEJ_01855 3.7e-87 2.7.6.5 T Region found in RelA / SpoT proteins
KMHNKCEJ_01856 1e-71
KMHNKCEJ_01857 5.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
KMHNKCEJ_01858 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
KMHNKCEJ_01859 1.1e-256 malT G Major Facilitator
KMHNKCEJ_01860 5.7e-214 phbA 2.3.1.9 I Belongs to the thiolase family
KMHNKCEJ_01861 4.3e-172 malR K Transcriptional regulator, LacI family
KMHNKCEJ_01862 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KMHNKCEJ_01863 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
KMHNKCEJ_01864 7.2e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KMHNKCEJ_01865 2e-103 wecD3 K PFAM GCN5-related N-acetyltransferase
KMHNKCEJ_01867 0.0 clpL O associated with various cellular activities
KMHNKCEJ_01868 7.8e-32
KMHNKCEJ_01869 1.2e-214 patA 2.6.1.1 E Aminotransferase
KMHNKCEJ_01870 3.2e-173 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KMHNKCEJ_01871 5e-75 osmC O OsmC-like protein
KMHNKCEJ_01872 4e-28
KMHNKCEJ_01873 1e-99 K DNA-templated transcription, initiation
KMHNKCEJ_01874 6.6e-37
KMHNKCEJ_01875 1.4e-84
KMHNKCEJ_01876 3.6e-290 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KMHNKCEJ_01877 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
KMHNKCEJ_01878 2.3e-294 yjbQ P TrkA C-terminal domain protein
KMHNKCEJ_01879 9.3e-272 pipD E Dipeptidase
KMHNKCEJ_01880 1.7e-38 ykuJ S Protein of unknown function (DUF1797)
KMHNKCEJ_01881 3.3e-178 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KMHNKCEJ_01882 4.5e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
KMHNKCEJ_01883 2.7e-227 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
KMHNKCEJ_01884 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KMHNKCEJ_01885 2.7e-39 ptsH G phosphocarrier protein HPR
KMHNKCEJ_01886 3.3e-40 L Type III restriction enzyme, res subunit
KMHNKCEJ_01887 1.3e-09
KMHNKCEJ_01888 5.2e-43 S SIR2-like domain
KMHNKCEJ_01889 4.6e-36 yhaI S Protein of unknown function (DUF805)
KMHNKCEJ_01890 8.5e-44
KMHNKCEJ_01891 2.4e-22
KMHNKCEJ_01892 2.1e-46
KMHNKCEJ_01893 8.2e-23 S YSIRK type signal peptide
KMHNKCEJ_01894 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KMHNKCEJ_01895 6.2e-216 ecsB U ABC transporter
KMHNKCEJ_01896 1.8e-136 ecsA V ABC transporter, ATP-binding protein
KMHNKCEJ_01897 3.2e-77 hit FG histidine triad
KMHNKCEJ_01899 8.5e-128 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KMHNKCEJ_01900 6e-32
KMHNKCEJ_01901 9.5e-18
KMHNKCEJ_01902 8.9e-64
KMHNKCEJ_01903 7.9e-34
KMHNKCEJ_01904 1.8e-206 potD P ABC transporter
KMHNKCEJ_01905 2.5e-139 potC P ABC transporter permease
KMHNKCEJ_01906 1.3e-145 potB P ABC transporter permease
KMHNKCEJ_01907 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KMHNKCEJ_01908 1.2e-23
KMHNKCEJ_01909 8.7e-41 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
KMHNKCEJ_01910 9.6e-44
KMHNKCEJ_01911 5.8e-169 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
KMHNKCEJ_01912 4.5e-250 mmuP E amino acid
KMHNKCEJ_01914 4.6e-64 S Alpha beta hydrolase
KMHNKCEJ_01915 2.3e-43 S Alpha beta hydrolase
KMHNKCEJ_01916 2.4e-215 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KMHNKCEJ_01917 1.7e-97
KMHNKCEJ_01919 1.3e-122 yciB M ErfK YbiS YcfS YnhG
KMHNKCEJ_01921 3.8e-159 metQ_4 P Belongs to the nlpA lipoprotein family
KMHNKCEJ_01922 9.7e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KMHNKCEJ_01923 1e-122 O Zinc-dependent metalloprotease
KMHNKCEJ_01924 9.6e-56 L Helix-turn-helix domain
KMHNKCEJ_01925 6.3e-148 L Transposase IS66 family
KMHNKCEJ_01926 5.9e-113 L Transposase IS66 family
KMHNKCEJ_01928 6.8e-36 XK27_01125 L PFAM IS66 Orf2 family protein
KMHNKCEJ_01929 1.2e-280 L Transposase IS66 family
KMHNKCEJ_01930 6e-64 gntR1 K Transcriptional regulator, GntR family
KMHNKCEJ_01931 4.4e-155 V ABC transporter, ATP-binding protein
KMHNKCEJ_01932 7.1e-116
KMHNKCEJ_01933 3.4e-140 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
KMHNKCEJ_01934 1.7e-100 S Pfam:DUF3816
KMHNKCEJ_01935 0.0 lacS G Transporter
KMHNKCEJ_01936 2.3e-28
KMHNKCEJ_01937 7.1e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KMHNKCEJ_01938 2.4e-286 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KMHNKCEJ_01939 4.4e-190 yeaN P Transporter, major facilitator family protein
KMHNKCEJ_01940 2.7e-73 S 3-demethylubiquinone-9 3-methyltransferase
KMHNKCEJ_01941 2.7e-82 nrdI F Belongs to the NrdI family
KMHNKCEJ_01942 1.6e-236 yhdP S Transporter associated domain
KMHNKCEJ_01943 1.1e-153 ypdB V (ABC) transporter
KMHNKCEJ_01944 2.5e-89 1.14.14.47, 1.6.5.3, 1.6.99.3 GM epimerase
KMHNKCEJ_01945 1.1e-89 M1-874 K Domain of unknown function (DUF1836)
KMHNKCEJ_01946 2.3e-78 yybA 2.3.1.57 K Transcriptional regulator
KMHNKCEJ_01947 1.7e-131 XK27_07210 6.1.1.6 S B3 4 domain
KMHNKCEJ_01948 2.6e-160 S AI-2E family transporter
KMHNKCEJ_01949 1.3e-156 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
KMHNKCEJ_01950 4.9e-160
KMHNKCEJ_01951 1e-133 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
KMHNKCEJ_01952 3.6e-138 eutJ E Hsp70 protein
KMHNKCEJ_01953 8.3e-159 K helix_turn_helix, arabinose operon control protein
KMHNKCEJ_01954 1.6e-37 pduA_4 CQ BMC
KMHNKCEJ_01955 2.7e-134 pduB E BMC
KMHNKCEJ_01956 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
KMHNKCEJ_01957 3.9e-125 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
KMHNKCEJ_01958 2.4e-71 pduE 4.2.1.28 Q Dehydratase small subunit
KMHNKCEJ_01959 5.6e-309 pduG D Diol dehydratase reactivase ATPase-like domain
KMHNKCEJ_01960 2.6e-45 pduH S Dehydratase medium subunit
KMHNKCEJ_01961 1.8e-56 pduK CQ BMC
KMHNKCEJ_01962 7.8e-40 pduA_4 CQ BMC
KMHNKCEJ_01963 1.9e-115 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
KMHNKCEJ_01964 1.3e-79 S Putative propanediol utilisation
KMHNKCEJ_01965 5.2e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
KMHNKCEJ_01966 1e-102 pduO 2.5.1.17 S Cobalamin adenosyltransferase
KMHNKCEJ_01967 4.5e-77 pduO S Haem-degrading
KMHNKCEJ_01968 3.1e-262 pduP 1.2.1.87 C Aldehyde dehydrogenase family
KMHNKCEJ_01969 2.1e-202 pduQ C Iron-containing alcohol dehydrogenase
KMHNKCEJ_01970 2.5e-217 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KMHNKCEJ_01971 3e-54 pduU E BMC
KMHNKCEJ_01972 1.1e-115 3.1.3.48 T Pfam:Y_phosphatase3C
KMHNKCEJ_01973 1.9e-75 pgm1 3.1.3.73 G phosphoglycerate mutase
KMHNKCEJ_01974 5.9e-68 P Cadmium resistance transporter
KMHNKCEJ_01975 2.6e-68 eutP E Ethanolamine utilisation - propanediol utilisation
KMHNKCEJ_01976 2.2e-73 fld C Flavodoxin
KMHNKCEJ_01977 8.7e-116 XK27_04590 S NADPH-dependent FMN reductase
KMHNKCEJ_01978 3.2e-77 cobO 2.5.1.17 S Cobalamin adenosyltransferase
KMHNKCEJ_01979 6.1e-170 cobD 4.1.1.81 E Aminotransferase class I and II
KMHNKCEJ_01980 7.3e-205 cbiA 6.3.5.11, 6.3.5.9 F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
KMHNKCEJ_01981 4.9e-147 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
KMHNKCEJ_01982 3.8e-109 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
KMHNKCEJ_01983 6.4e-186 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
KMHNKCEJ_01984 1.6e-79 cbiE 2.1.1.132, 2.1.1.289 H Tetrapyrrole (Corrin/Porphyrin) Methylases
KMHNKCEJ_01985 1.4e-77 cbiT 2.1.1.132, 2.1.1.196 H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
KMHNKCEJ_01986 8.1e-129 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
KMHNKCEJ_01987 3e-145 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
KMHNKCEJ_01988 6.6e-128 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H Tetrapyrrole (Corrin/Porphyrin) Methylases
KMHNKCEJ_01989 2.8e-97 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H Precorrin-6x reductase CbiJ/CobK
KMHNKCEJ_01990 2.8e-175 cobA 2.1.1.107, 4.2.1.75 H Tetrapyrrole (Corrin/Porphyrin) Methylases
KMHNKCEJ_01991 8.1e-108 cbiK 4.99.1.3 H Cobalt chelatase (CbiK)
KMHNKCEJ_01992 8.1e-91 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Tetrapyrrole (Corrin/Porphyrin) Methylases
KMHNKCEJ_01993 1e-123 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
KMHNKCEJ_01994 7.6e-44 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
KMHNKCEJ_01995 6.8e-103 cbiQ P Cobalt transport protein
KMHNKCEJ_01996 7.8e-122 cbiO 2.1.1.195 P part of an ABC transporter complex. Responsible for energy coupling to the transport system
KMHNKCEJ_01997 2.7e-240 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
KMHNKCEJ_01998 1.6e-58 cysG 1.3.1.76, 4.99.1.4 H Putative NAD(P)-binding
KMHNKCEJ_01999 1.7e-192 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KMHNKCEJ_02000 2.6e-137 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
KMHNKCEJ_02001 2.8e-174 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
KMHNKCEJ_02002 1.1e-239 hemL 5.4.3.8 H Aminotransferase class-III
KMHNKCEJ_02003 1.6e-76 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Cobinamide kinase / cobinamide phosphate guanyltransferase
KMHNKCEJ_02004 2.2e-118 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
KMHNKCEJ_02005 5.8e-74 gpm 3.1.3.73, 5.4.2.12 G Belongs to the phosphoglycerate mutase family
KMHNKCEJ_02006 6.5e-64 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
KMHNKCEJ_02007 1.3e-145 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
KMHNKCEJ_02008 4.3e-13
KMHNKCEJ_02009 8.2e-205 cytX U Belongs to the purine-cytosine permease (2.A.39) family
KMHNKCEJ_02010 1.7e-95 ltrA S Bacterial low temperature requirement A protein (LtrA)
KMHNKCEJ_02011 1.5e-42 wecD3 K PFAM GCN5-related N-acetyltransferase
KMHNKCEJ_02012 1e-182
KMHNKCEJ_02013 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KMHNKCEJ_02014 5.8e-184 S Phosphotransferase system, EIIC
KMHNKCEJ_02016 7.2e-128 tesE Q hydratase
KMHNKCEJ_02017 8.8e-117 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KMHNKCEJ_02019 6.8e-54
KMHNKCEJ_02020 2.6e-112 frnE Q DSBA-like thioredoxin domain
KMHNKCEJ_02021 4.7e-114 I alpha/beta hydrolase fold
KMHNKCEJ_02022 8.5e-20 K Helix-turn-helix XRE-family like proteins
KMHNKCEJ_02023 7.6e-23 S Phage derived protein Gp49-like (DUF891)
KMHNKCEJ_02024 6.1e-57
KMHNKCEJ_02025 0.0 S Peptidase, M23
KMHNKCEJ_02026 2.5e-36
KMHNKCEJ_02027 0.0 yhcA V ABC transporter, ATP-binding protein
KMHNKCEJ_02028 1.1e-26
KMHNKCEJ_02029 0.0 clpE O Belongs to the ClpA ClpB family
KMHNKCEJ_02030 6.6e-254 yifK E Amino acid permease
KMHNKCEJ_02052 8.7e-65 XK27_01125 L PFAM IS66 Orf2 family protein
KMHNKCEJ_02053 1.3e-14 K Cro/C1-type HTH DNA-binding domain
KMHNKCEJ_02057 1.7e-263 dtpT U amino acid peptide transporter
KMHNKCEJ_02058 2.2e-148 yjjH S Calcineurin-like phosphoesterase
KMHNKCEJ_02061 3.6e-109
KMHNKCEJ_02062 6.5e-249 EGP Major facilitator Superfamily
KMHNKCEJ_02063 1.1e-300 aspT P Predicted Permease Membrane Region
KMHNKCEJ_02064 2.2e-131 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
KMHNKCEJ_02065 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
KMHNKCEJ_02066 3.1e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KMHNKCEJ_02067 2e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KMHNKCEJ_02068 0.0 yhgF K Tex-like protein N-terminal domain protein
KMHNKCEJ_02069 8.1e-84 ydcK S Belongs to the SprT family
KMHNKCEJ_02071 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
KMHNKCEJ_02072 2.9e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
KMHNKCEJ_02073 0.0 S Bacterial membrane protein, YfhO
KMHNKCEJ_02074 3e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KMHNKCEJ_02075 2.3e-167 I alpha/beta hydrolase fold
KMHNKCEJ_02076 5e-215 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KMHNKCEJ_02077 1.1e-119 tcyB E ABC transporter
KMHNKCEJ_02078 1.1e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KMHNKCEJ_02079 6.2e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
KMHNKCEJ_02080 1.5e-266 pepC 3.4.22.40 E Peptidase C1-like family
KMHNKCEJ_02081 1.3e-125 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KMHNKCEJ_02082 1.9e-49 HA62_12640 S GCN5-related N-acetyl-transferase
KMHNKCEJ_02083 7.3e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
KMHNKCEJ_02084 5e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KMHNKCEJ_02085 4.7e-205 yacL S domain protein
KMHNKCEJ_02086 4.7e-271 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KMHNKCEJ_02087 2.1e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KMHNKCEJ_02088 2.3e-136 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KMHNKCEJ_02089 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KMHNKCEJ_02090 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KMHNKCEJ_02091 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
KMHNKCEJ_02092 2.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KMHNKCEJ_02093 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KMHNKCEJ_02094 5.6e-225 aadAT EK Aminotransferase, class I
KMHNKCEJ_02096 6.7e-19 M Glycosyl transferase family group 2
KMHNKCEJ_02097 1.5e-178 M Glycosyl transferase family group 2
KMHNKCEJ_02098 4.4e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KMHNKCEJ_02099 4.9e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KMHNKCEJ_02100 5.4e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KMHNKCEJ_02101 2e-26
KMHNKCEJ_02103 3.2e-38 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KMHNKCEJ_02104 5.2e-23 K transcriptional regulator PadR family
KMHNKCEJ_02105 2.1e-101 L Bacterial dnaA protein
KMHNKCEJ_02106 4.4e-229 L Integrase core domain
KMHNKCEJ_02107 6.5e-39 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KMHNKCEJ_02108 8.6e-33 K transcriptional regulator PadR family
KMHNKCEJ_02109 1.2e-82 XK27_06920 S Protein of unknown function (DUF1700)
KMHNKCEJ_02110 5.4e-133 S Putative adhesin
KMHNKCEJ_02111 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KMHNKCEJ_02112 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KMHNKCEJ_02113 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KMHNKCEJ_02114 3.4e-35 nrdH O Glutaredoxin
KMHNKCEJ_02115 1e-87 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KMHNKCEJ_02116 4.3e-285 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KMHNKCEJ_02117 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KMHNKCEJ_02118 5.3e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KMHNKCEJ_02119 2.8e-38 S Protein of unknown function (DUF2508)
KMHNKCEJ_02120 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KMHNKCEJ_02121 2.9e-51 yaaQ S Cyclic-di-AMP receptor
KMHNKCEJ_02122 1e-179 holB 2.7.7.7 L DNA polymerase III
KMHNKCEJ_02123 3.1e-43 yabA L Involved in initiation control of chromosome replication
KMHNKCEJ_02124 2.9e-154 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KMHNKCEJ_02125 1.6e-132 fat 3.1.2.21 I Acyl-ACP thioesterase
KMHNKCEJ_02126 8.8e-223 L Transposase
KMHNKCEJ_02127 3e-30 K Cold-Shock Protein
KMHNKCEJ_02131 1.5e-203 L Transposase
KMHNKCEJ_02132 2e-09 IQ KR domain
KMHNKCEJ_02133 4e-34 IQ KR domain
KMHNKCEJ_02134 3.3e-133 S membrane transporter protein
KMHNKCEJ_02135 8.7e-156 L Transposase
KMHNKCEJ_02140 2.9e-151 S Phosphotransferase system, EIIC
KMHNKCEJ_02141 2.7e-28 L transposition
KMHNKCEJ_02142 1.3e-22 L Transposase
KMHNKCEJ_02143 5.5e-46 L transposase activity
KMHNKCEJ_02144 7.7e-62 3.6.3.8 P cation transport ATPase
KMHNKCEJ_02145 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
KMHNKCEJ_02146 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KMHNKCEJ_02147 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KMHNKCEJ_02148 3.5e-163 S Tetratricopeptide repeat
KMHNKCEJ_02149 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KMHNKCEJ_02150 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KMHNKCEJ_02151 1.8e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KMHNKCEJ_02152 2.6e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
KMHNKCEJ_02153 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
KMHNKCEJ_02154 7.6e-09
KMHNKCEJ_02155 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KMHNKCEJ_02156 5.2e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KMHNKCEJ_02157 3.7e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KMHNKCEJ_02158 1.1e-155 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KMHNKCEJ_02159 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
KMHNKCEJ_02160 9.2e-92 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KMHNKCEJ_02161 2.5e-88
KMHNKCEJ_02163 5.7e-126 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KMHNKCEJ_02164 6e-208 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
KMHNKCEJ_02165 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KMHNKCEJ_02166 1.3e-35 ynzC S UPF0291 protein
KMHNKCEJ_02167 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
KMHNKCEJ_02168 1.6e-117 plsC 2.3.1.51 I Acyltransferase
KMHNKCEJ_02169 5.4e-141 yabB 2.1.1.223 L Methyltransferase small domain
KMHNKCEJ_02170 5.4e-49 yazA L GIY-YIG catalytic domain protein
KMHNKCEJ_02171 5.9e-180 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KMHNKCEJ_02172 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
KMHNKCEJ_02173 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KMHNKCEJ_02174 4.1e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KMHNKCEJ_02175 4.8e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KMHNKCEJ_02176 2.4e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KMHNKCEJ_02177 1.7e-137 cdsA 2.7.7.41 I Belongs to the CDS family
KMHNKCEJ_02178 3.7e-235 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
KMHNKCEJ_02179 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KMHNKCEJ_02180 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KMHNKCEJ_02181 1.2e-82 rimP J Required for maturation of 30S ribosomal subunits
KMHNKCEJ_02182 1.4e-215 nusA K Participates in both transcription termination and antitermination
KMHNKCEJ_02183 1e-44 ylxR K Protein of unknown function (DUF448)
KMHNKCEJ_02184 1.3e-48 ylxQ J ribosomal protein
KMHNKCEJ_02185 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KMHNKCEJ_02186 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KMHNKCEJ_02187 7.1e-164 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KMHNKCEJ_02188 8.5e-176 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KMHNKCEJ_02189 7.6e-64
KMHNKCEJ_02190 5.9e-194 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KMHNKCEJ_02191 1.3e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KMHNKCEJ_02192 0.0 dnaK O Heat shock 70 kDa protein
KMHNKCEJ_02193 8.1e-197 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KMHNKCEJ_02194 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)