ORF_ID e_value Gene_name EC_number CAZy COGs Description
NPHDNIAI_00001 2e-09 IQ KR domain
NPHDNIAI_00002 4e-34 IQ KR domain
NPHDNIAI_00003 3.2e-59 IQ KR domain
NPHDNIAI_00004 3.3e-133 S membrane transporter protein
NPHDNIAI_00024 3.3e-260 L Transposase
NPHDNIAI_00025 2.5e-185 L transposase, IS605 OrfB family
NPHDNIAI_00026 4.2e-51 L Transposase IS200 like
NPHDNIAI_00027 2.9e-151 S Phosphotransferase system, EIIC
NPHDNIAI_00028 4e-28
NPHDNIAI_00029 2.4e-101 K DNA-templated transcription, initiation
NPHDNIAI_00030 6.6e-37
NPHDNIAI_00031 5.1e-139 L Bacterial dnaA protein
NPHDNIAI_00032 1.6e-42 L Integrase core domain
NPHDNIAI_00033 1.3e-24 L Integrase core domain
NPHDNIAI_00034 6.3e-265 L PFAM Integrase catalytic region
NPHDNIAI_00035 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NPHDNIAI_00036 1.7e-260 yfnA E amino acid
NPHDNIAI_00037 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NPHDNIAI_00038 6.9e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NPHDNIAI_00039 5.4e-40 ylqC S Belongs to the UPF0109 family
NPHDNIAI_00040 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NPHDNIAI_00041 1.8e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NPHDNIAI_00042 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NPHDNIAI_00043 4.2e-177 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NPHDNIAI_00044 0.0 smc D Required for chromosome condensation and partitioning
NPHDNIAI_00045 6.1e-131 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NPHDNIAI_00046 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NPHDNIAI_00047 1e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NPHDNIAI_00048 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NPHDNIAI_00049 0.0 yloV S DAK2 domain fusion protein YloV
NPHDNIAI_00050 4.7e-58 asp S Asp23 family, cell envelope-related function
NPHDNIAI_00051 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NPHDNIAI_00052 2.4e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
NPHDNIAI_00053 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NPHDNIAI_00054 1.5e-161 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NPHDNIAI_00055 0.0 KLT serine threonine protein kinase
NPHDNIAI_00056 2.1e-129 stp 3.1.3.16 T phosphatase
NPHDNIAI_00057 2.4e-248 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NPHDNIAI_00058 1.4e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NPHDNIAI_00059 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NPHDNIAI_00060 1.3e-208 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NPHDNIAI_00061 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NPHDNIAI_00062 3.5e-114 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NPHDNIAI_00063 1.6e-52
NPHDNIAI_00064 5.5e-263 recN L May be involved in recombinational repair of damaged DNA
NPHDNIAI_00065 1.8e-75 argR K Regulates arginine biosynthesis genes
NPHDNIAI_00066 3.4e-149 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NPHDNIAI_00067 6.4e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NPHDNIAI_00068 1.3e-42 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NPHDNIAI_00069 9.3e-213 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NPHDNIAI_00070 1.4e-148 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NPHDNIAI_00071 4.7e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NPHDNIAI_00072 2.2e-70 yqhY S Asp23 family, cell envelope-related function
NPHDNIAI_00073 6.6e-114 J 2'-5' RNA ligase superfamily
NPHDNIAI_00074 1.6e-199 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NPHDNIAI_00075 2.6e-129 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NPHDNIAI_00076 1.3e-44 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NPHDNIAI_00077 9e-53 ysxB J Cysteine protease Prp
NPHDNIAI_00078 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
NPHDNIAI_00079 4.7e-103 K Transcriptional regulator
NPHDNIAI_00082 8.2e-85 dut S Protein conserved in bacteria
NPHDNIAI_00083 4.3e-181
NPHDNIAI_00084 9.7e-150
NPHDNIAI_00085 6.3e-148 L Transposase IS66 family
NPHDNIAI_00086 3.2e-36 mmuP E amino acid
NPHDNIAI_00088 1.4e-175 csd1 3.5.1.28 G domain, Protein
NPHDNIAI_00089 7.9e-145 L PFAM Integrase catalytic region
NPHDNIAI_00090 2.6e-188 L PFAM Integrase catalytic region
NPHDNIAI_00092 4.1e-141 L transposase, IS605 OrfB family
NPHDNIAI_00095 2.6e-09 E Collagen triple helix repeat (20 copies)
NPHDNIAI_00096 1.7e-135 lysA2 M Glycosyl hydrolases family 25
NPHDNIAI_00097 4.6e-35 S Bacteriophage holin of superfamily 6 (Holin_LLH)
NPHDNIAI_00098 3.9e-40
NPHDNIAI_00099 3.7e-12
NPHDNIAI_00100 6.8e-68 S Domain of unknown function (DUF2479)
NPHDNIAI_00101 1.7e-77 3.2.1.11 GH66 G Glycosyl hydrolase family 66
NPHDNIAI_00104 3.4e-191 S Peptidase family M23
NPHDNIAI_00105 2.6e-97 S Phage tail protein
NPHDNIAI_00106 1.5e-300 D NLP P60 protein
NPHDNIAI_00107 2.2e-88 S Phage tail assembly chaperone protein, TAC
NPHDNIAI_00108 1.4e-84
NPHDNIAI_00109 3.3e-68
NPHDNIAI_00110 2.9e-83
NPHDNIAI_00111 2.4e-42
NPHDNIAI_00112 9.2e-62 S Phage gp6-like head-tail connector protein
NPHDNIAI_00113 1.1e-200 gpG
NPHDNIAI_00114 1e-82 S Domain of unknown function (DUF4355)
NPHDNIAI_00115 2.2e-176 S Phage Mu protein F like protein
NPHDNIAI_00116 3e-301 S Phage portal protein, SPP1 Gp6-like
NPHDNIAI_00117 1.8e-261 S Phage terminase, large subunit
NPHDNIAI_00118 3.3e-28
NPHDNIAI_00119 1.2e-08
NPHDNIAI_00120 6.5e-41 S RloB-like protein
NPHDNIAI_00121 2.2e-118 S AAA domain, putative AbiEii toxin, Type IV TA system
NPHDNIAI_00122 3.9e-72
NPHDNIAI_00126 1.9e-28 rusA L Endodeoxyribonuclease RusA
NPHDNIAI_00127 3e-19
NPHDNIAI_00130 5.5e-30
NPHDNIAI_00133 1.6e-56 dnaC 3.4.21.53 L IstB-like ATP binding protein
NPHDNIAI_00134 6.5e-76 L Psort location Cytoplasmic, score
NPHDNIAI_00135 2.8e-159 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
NPHDNIAI_00136 5.2e-109 recT L RecT family
NPHDNIAI_00145 1.9e-82 S Phage antirepressor protein KilAC domain
NPHDNIAI_00146 1e-22 S sequence-specific DNA binding
NPHDNIAI_00148 2e-17
NPHDNIAI_00149 2.1e-63 V Abi-like protein
NPHDNIAI_00150 3.2e-235 int L COG1961 Site-specific recombinases, DNA invertase Pin homologs
NPHDNIAI_00153 3.2e-29 MA20_14895 S Conserved hypothetical protein 698
NPHDNIAI_00155 3.5e-97 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NPHDNIAI_00156 5.3e-31
NPHDNIAI_00157 1.8e-108 S CAAX protease self-immunity
NPHDNIAI_00158 1.9e-43
NPHDNIAI_00160 4.3e-59
NPHDNIAI_00162 3.2e-68
NPHDNIAI_00164 8.7e-14 S calcium ion binding
NPHDNIAI_00168 1.3e-08
NPHDNIAI_00171 2.4e-29 L Phage regulatory protein
NPHDNIAI_00172 4.2e-27
NPHDNIAI_00173 2.7e-17 S Helix-turn-helix domain
NPHDNIAI_00174 8.8e-11 K Transcriptional regulator
NPHDNIAI_00175 2.3e-140 L Belongs to the 'phage' integrase family
NPHDNIAI_00176 1.9e-68
NPHDNIAI_00177 2.6e-55 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NPHDNIAI_00178 2.9e-90 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
NPHDNIAI_00179 6.9e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
NPHDNIAI_00180 4.7e-222 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NPHDNIAI_00181 7.7e-103 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
NPHDNIAI_00182 1.3e-210 folP 2.5.1.15 H dihydropteroate synthase
NPHDNIAI_00183 6.7e-43
NPHDNIAI_00184 4.8e-39
NPHDNIAI_00186 4.2e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NPHDNIAI_00187 7.3e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NPHDNIAI_00188 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NPHDNIAI_00189 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NPHDNIAI_00190 5.9e-40 yheA S Belongs to the UPF0342 family
NPHDNIAI_00191 4.8e-221 yhaO L Ser Thr phosphatase family protein
NPHDNIAI_00192 0.0 L AAA domain
NPHDNIAI_00193 1.4e-127 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NPHDNIAI_00195 4.1e-77 hit FG histidine triad
NPHDNIAI_00196 1.8e-136 ecsA V ABC transporter, ATP-binding protein
NPHDNIAI_00197 2.5e-217 ecsB U ABC transporter
NPHDNIAI_00198 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NPHDNIAI_00199 8.4e-23 S YSIRK type signal peptide
NPHDNIAI_00200 2.3e-102 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
NPHDNIAI_00201 7.4e-112 2.7.7.7, 3.4.21.110 D Leucine-rich repeat (LRR) protein
NPHDNIAI_00202 3.6e-68 L Transposase
NPHDNIAI_00203 1.8e-150 L Transposase
NPHDNIAI_00204 3.4e-83 iolS C Aldo keto reductase
NPHDNIAI_00205 3.7e-11 iolS C Aldo keto reductase
NPHDNIAI_00206 2e-115 glsA 3.5.1.2 E Belongs to the glutaminase family
NPHDNIAI_00207 1.3e-10 glsA 3.5.1.2 E Belongs to the glutaminase family
NPHDNIAI_00208 7.5e-58 ytzB S Small secreted protein
NPHDNIAI_00209 1.9e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NPHDNIAI_00210 1.1e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NPHDNIAI_00211 4.5e-252 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NPHDNIAI_00212 1.9e-119 ybhL S Belongs to the BI1 family
NPHDNIAI_00213 8.3e-61 yoaK S Protein of unknown function (DUF1275)
NPHDNIAI_00214 5.1e-15 yoaK S Protein of unknown function (DUF1275)
NPHDNIAI_00215 2.2e-128 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
NPHDNIAI_00216 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NPHDNIAI_00217 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NPHDNIAI_00218 1.5e-173 K AI-2E family transporter
NPHDNIAI_00219 1.5e-227 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
NPHDNIAI_00220 7.9e-96 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NPHDNIAI_00221 3.7e-114 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
NPHDNIAI_00222 9.6e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NPHDNIAI_00223 6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NPHDNIAI_00224 1e-170 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NPHDNIAI_00225 2.1e-246 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NPHDNIAI_00226 5e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NPHDNIAI_00227 2.9e-124 K LysR substrate binding domain
NPHDNIAI_00228 1.6e-52 azlD S branched-chain amino acid
NPHDNIAI_00229 2.3e-138 azlC E AzlC protein
NPHDNIAI_00230 8.3e-202 hpk31 2.7.13.3 T Histidine kinase
NPHDNIAI_00231 3.8e-125 K response regulator
NPHDNIAI_00232 2e-208 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NPHDNIAI_00233 4e-170 deoR K sugar-binding domain protein
NPHDNIAI_00234 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
NPHDNIAI_00235 3.5e-233 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
NPHDNIAI_00236 4.5e-235 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NPHDNIAI_00237 3.4e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NPHDNIAI_00238 3.1e-136 XK27_01040 S Protein of unknown function (DUF1129)
NPHDNIAI_00239 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NPHDNIAI_00240 1.2e-31 yyzM S Bacterial protein of unknown function (DUF951)
NPHDNIAI_00241 5e-154 spo0J K Belongs to the ParB family
NPHDNIAI_00242 3.6e-140 soj D Sporulation initiation inhibitor
NPHDNIAI_00243 1.5e-143 noc K Belongs to the ParB family
NPHDNIAI_00244 3.7e-123 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
NPHDNIAI_00245 7.7e-163 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
NPHDNIAI_00246 1.9e-169 rihC 3.2.2.1 F Nucleoside
NPHDNIAI_00247 1.3e-218 nupG F Nucleoside transporter
NPHDNIAI_00248 1.6e-220 cycA E Amino acid permease
NPHDNIAI_00249 1.9e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NPHDNIAI_00250 2.2e-263 glnP P ABC transporter
NPHDNIAI_00251 1.2e-249 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NPHDNIAI_00252 6.3e-37 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NPHDNIAI_00254 7.7e-180 galR K Transcriptional regulator
NPHDNIAI_00255 1.7e-276 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NPHDNIAI_00256 1.1e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NPHDNIAI_00257 2.1e-177 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
NPHDNIAI_00258 1.9e-144 ptp3 3.1.3.48 T Tyrosine phosphatase family
NPHDNIAI_00259 4.1e-92 yxkA S Phosphatidylethanolamine-binding protein
NPHDNIAI_00260 9.1e-36
NPHDNIAI_00261 2e-52
NPHDNIAI_00262 1.1e-201
NPHDNIAI_00263 1.1e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NPHDNIAI_00264 2.9e-134 pnuC H nicotinamide mononucleotide transporter
NPHDNIAI_00265 9.1e-30 ytbE 1.1.1.346 S Aldo keto reductase
NPHDNIAI_00266 1.2e-123 K response regulator
NPHDNIAI_00267 9e-181 T PhoQ Sensor
NPHDNIAI_00268 1.9e-133 macB2 V ABC transporter, ATP-binding protein
NPHDNIAI_00269 0.0 ysaB V FtsX-like permease family
NPHDNIAI_00270 2.2e-156 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
NPHDNIAI_00271 7e-167 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NPHDNIAI_00272 6.2e-10 K helix_turn_helix, mercury resistance
NPHDNIAI_00273 2.4e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NPHDNIAI_00274 1e-194 EGP Major facilitator Superfamily
NPHDNIAI_00275 3.9e-87 ymdB S Macro domain protein
NPHDNIAI_00276 1.4e-105 K Helix-turn-helix XRE-family like proteins
NPHDNIAI_00277 0.0 pepO 3.4.24.71 O Peptidase family M13
NPHDNIAI_00278 1.4e-47
NPHDNIAI_00279 6e-233 S Putative metallopeptidase domain
NPHDNIAI_00280 4.4e-203 3.1.3.1 S associated with various cellular activities
NPHDNIAI_00281 5.2e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NPHDNIAI_00282 5.9e-64 yeaO S Protein of unknown function, DUF488
NPHDNIAI_00284 1.5e-118 yrkL S Flavodoxin-like fold
NPHDNIAI_00285 1.5e-52
NPHDNIAI_00286 5.3e-16 S Domain of unknown function (DUF4767)
NPHDNIAI_00287 4.2e-29 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NPHDNIAI_00288 9.1e-49
NPHDNIAI_00289 8.9e-206 nrnB S DHHA1 domain
NPHDNIAI_00290 6.2e-227 S Uncharacterized protein conserved in bacteria (DUF2325)
NPHDNIAI_00291 1.2e-247 brnQ U Component of the transport system for branched-chain amino acids
NPHDNIAI_00292 1.1e-104 NU mannosyl-glycoprotein
NPHDNIAI_00293 5e-142 S Putative ABC-transporter type IV
NPHDNIAI_00294 7.1e-273 S ABC transporter, ATP-binding protein
NPHDNIAI_00295 6.4e-08 S HTH domain
NPHDNIAI_00296 2.4e-34 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
NPHDNIAI_00297 2.9e-33 arsB 1.20.4.1 P Sodium Bile acid symporter family
NPHDNIAI_00298 1e-48 yjcE P Sodium proton antiporter
NPHDNIAI_00299 1.4e-42 yjcE P Sodium proton antiporter
NPHDNIAI_00300 7.9e-24 yjcE P Sodium proton antiporter
NPHDNIAI_00302 1.3e-90
NPHDNIAI_00303 2e-297 M domain protein
NPHDNIAI_00304 4.1e-160 M domain protein
NPHDNIAI_00305 2.5e-32
NPHDNIAI_00306 9.1e-184 ampC V Beta-lactamase
NPHDNIAI_00307 8.9e-218 arcA 3.5.3.6 E Arginine
NPHDNIAI_00308 2.7e-79 argR K Regulates arginine biosynthesis genes
NPHDNIAI_00309 1.4e-259 E Arginine ornithine antiporter
NPHDNIAI_00310 7.5e-221 arcD U Amino acid permease
NPHDNIAI_00311 1.2e-134 cobQ S CobB/CobQ-like glutamine amidotransferase domain
NPHDNIAI_00312 7.5e-263 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
NPHDNIAI_00313 6e-108 tdk 2.7.1.21 F thymidine kinase
NPHDNIAI_00314 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NPHDNIAI_00315 6.1e-165 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NPHDNIAI_00316 1.4e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NPHDNIAI_00317 2.3e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NPHDNIAI_00318 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NPHDNIAI_00319 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NPHDNIAI_00320 4.4e-192 yibE S overlaps another CDS with the same product name
NPHDNIAI_00321 2.6e-130 yibF S overlaps another CDS with the same product name
NPHDNIAI_00322 5.9e-233 pyrP F Permease
NPHDNIAI_00323 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
NPHDNIAI_00324 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NPHDNIAI_00325 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NPHDNIAI_00326 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NPHDNIAI_00327 1.5e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NPHDNIAI_00328 7.4e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NPHDNIAI_00329 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NPHDNIAI_00330 1e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NPHDNIAI_00331 1.3e-33 ywzB S Protein of unknown function (DUF1146)
NPHDNIAI_00332 6.8e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NPHDNIAI_00333 1.9e-178 mbl D Cell shape determining protein MreB Mrl
NPHDNIAI_00334 4.4e-41 yidD S Could be involved in insertion of integral membrane proteins into the membrane
NPHDNIAI_00335 1e-31 S Protein of unknown function (DUF2969)
NPHDNIAI_00336 4.1e-220 rodA D Belongs to the SEDS family
NPHDNIAI_00337 1.4e-47 gcvH E glycine cleavage
NPHDNIAI_00338 5.3e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NPHDNIAI_00339 3.7e-146 2.3.1.19 K Helix-turn-helix XRE-family like proteins
NPHDNIAI_00340 1.3e-96 S ABC-type cobalt transport system, permease component
NPHDNIAI_00341 4.9e-249 cbiO1 S ABC transporter, ATP-binding protein
NPHDNIAI_00342 6.6e-111 P Cobalt transport protein
NPHDNIAI_00343 1.6e-52 yvlA
NPHDNIAI_00344 0.0 yjcE P Sodium proton antiporter
NPHDNIAI_00345 1.1e-51 ypaA S Protein of unknown function (DUF1304)
NPHDNIAI_00346 3.4e-172 D Alpha beta
NPHDNIAI_00347 1e-72 K Transcriptional regulator
NPHDNIAI_00348 8.5e-159
NPHDNIAI_00349 2.3e-50 1.6.5.5 C Zinc-binding dehydrogenase
NPHDNIAI_00350 2.4e-70 1.6.5.5 C Zinc-binding dehydrogenase
NPHDNIAI_00351 8.2e-31 1.6.5.5 C Zinc-binding dehydrogenase
NPHDNIAI_00352 2.7e-255 G PTS system Galactitol-specific IIC component
NPHDNIAI_00353 5.9e-211 EGP Major facilitator Superfamily
NPHDNIAI_00354 3.9e-135 V ABC transporter
NPHDNIAI_00355 9e-106
NPHDNIAI_00356 4e-14
NPHDNIAI_00357 7.1e-63
NPHDNIAI_00358 1.5e-194 lplA 6.3.1.20 H Lipoate-protein ligase
NPHDNIAI_00359 6.6e-81 uspA T universal stress protein
NPHDNIAI_00360 0.0 tetP J elongation factor G
NPHDNIAI_00361 2.9e-165 GK ROK family
NPHDNIAI_00362 1.6e-236 brnQ U Component of the transport system for branched-chain amino acids
NPHDNIAI_00363 3.2e-138 aroD S Serine hydrolase (FSH1)
NPHDNIAI_00364 5.5e-237 yagE E amino acid
NPHDNIAI_00365 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
NPHDNIAI_00366 4.7e-126 gntR K UbiC transcription regulator-associated domain protein
NPHDNIAI_00367 1.6e-85 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NPHDNIAI_00368 2.6e-269 pipD E Dipeptidase
NPHDNIAI_00369 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
NPHDNIAI_00370 0.0 yfiC V ABC transporter
NPHDNIAI_00371 9.8e-287 lmrA V ABC transporter, ATP-binding protein
NPHDNIAI_00372 1.7e-17 K Winged helix DNA-binding domain
NPHDNIAI_00373 1.9e-179 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPHDNIAI_00374 2.9e-19 S PFAM Archaeal ATPase
NPHDNIAI_00375 5.9e-73 S ECF transporter, substrate-specific component
NPHDNIAI_00376 9.8e-51 S Domain of unknown function (DUF4430)
NPHDNIAI_00377 8.6e-20 cnrT EG PFAM EamA-like transporter family
NPHDNIAI_00378 2.6e-29
NPHDNIAI_00379 8.8e-35 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NPHDNIAI_00380 2.2e-146 ykuT M mechanosensitive ion channel
NPHDNIAI_00381 1e-153 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
NPHDNIAI_00382 1.1e-74 ykuL S (CBS) domain
NPHDNIAI_00383 1.7e-93 S Phosphoesterase
NPHDNIAI_00384 9.8e-106 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NPHDNIAI_00385 3.1e-147 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NPHDNIAI_00386 1.6e-97 yslB S Protein of unknown function (DUF2507)
NPHDNIAI_00387 6.1e-54 trxA O Belongs to the thioredoxin family
NPHDNIAI_00388 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NPHDNIAI_00389 2.7e-86 cvpA S Colicin V production protein
NPHDNIAI_00390 6.1e-48 yrzB S Belongs to the UPF0473 family
NPHDNIAI_00391 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NPHDNIAI_00392 4.1e-43 yrzL S Belongs to the UPF0297 family
NPHDNIAI_00393 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NPHDNIAI_00394 3.7e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NPHDNIAI_00395 3.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
NPHDNIAI_00396 6.2e-31 yajC U Preprotein translocase
NPHDNIAI_00397 5.9e-189 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NPHDNIAI_00398 2.9e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NPHDNIAI_00399 4.3e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NPHDNIAI_00400 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NPHDNIAI_00401 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NPHDNIAI_00402 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
NPHDNIAI_00403 1.9e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NPHDNIAI_00404 1.4e-226 cinA 3.5.1.42 S Belongs to the CinA family
NPHDNIAI_00405 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NPHDNIAI_00406 1.7e-137 ymfM S Helix-turn-helix domain
NPHDNIAI_00407 2.5e-247 ymfH S Peptidase M16
NPHDNIAI_00408 1.6e-227 ymfF S Peptidase M16 inactive domain protein
NPHDNIAI_00409 2.9e-159 aatB ET ABC transporter substrate-binding protein
NPHDNIAI_00410 1.2e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NPHDNIAI_00411 4.2e-102 glnP P ABC transporter permease
NPHDNIAI_00412 8.7e-93 mreD M rod shape-determining protein MreD
NPHDNIAI_00413 3.5e-152 mreC M Involved in formation and maintenance of cell shape
NPHDNIAI_00414 1.7e-179 mreB D cell shape determining protein MreB
NPHDNIAI_00415 8e-122 radC L DNA repair protein
NPHDNIAI_00416 2.5e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NPHDNIAI_00417 1.8e-231 ndh 1.6.99.3 C NADH dehydrogenase
NPHDNIAI_00418 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NPHDNIAI_00419 7e-311 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NPHDNIAI_00420 4.5e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
NPHDNIAI_00421 7.2e-272 cydA 1.10.3.14 C ubiquinol oxidase
NPHDNIAI_00422 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NPHDNIAI_00423 3.2e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NPHDNIAI_00424 8.6e-215 iscS2 2.8.1.7 E Aminotransferase class V
NPHDNIAI_00425 9.7e-239 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NPHDNIAI_00426 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NPHDNIAI_00427 1.6e-66 gadC E amino acid
NPHDNIAI_00428 4.6e-156 gadC E amino acid
NPHDNIAI_00429 1.1e-275 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
NPHDNIAI_00430 1.1e-234 pbuG S permease
NPHDNIAI_00431 9.4e-236 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NPHDNIAI_00432 3.1e-13 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NPHDNIAI_00433 5.3e-33 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
NPHDNIAI_00434 1.2e-258 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
NPHDNIAI_00435 1e-139 S Belongs to the UPF0246 family
NPHDNIAI_00436 2.5e-138 S Membrane
NPHDNIAI_00437 8.1e-75 4.4.1.5 E Glyoxalase
NPHDNIAI_00438 4.5e-21
NPHDNIAI_00439 2.7e-85 yueI S Protein of unknown function (DUF1694)
NPHDNIAI_00440 1.4e-234 rarA L recombination factor protein RarA
NPHDNIAI_00441 1.3e-45
NPHDNIAI_00442 2.8e-82 usp6 T universal stress protein
NPHDNIAI_00443 5.9e-205 araR K Transcriptional regulator
NPHDNIAI_00444 2.5e-155 ytbE 1.1.1.346 S Aldo keto reductase
NPHDNIAI_00445 2.4e-90 maa 2.3.1.79 S Maltose O-acetyltransferase
NPHDNIAI_00446 1.4e-283 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
NPHDNIAI_00447 3.7e-139 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NPHDNIAI_00448 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
NPHDNIAI_00449 1.2e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NPHDNIAI_00450 0.0 L Helicase C-terminal domain protein
NPHDNIAI_00451 1.6e-46 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
NPHDNIAI_00452 6.3e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NPHDNIAI_00453 6.7e-187 yegS 2.7.1.107 G Lipid kinase
NPHDNIAI_00454 1.8e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NPHDNIAI_00455 5.9e-277 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NPHDNIAI_00456 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NPHDNIAI_00457 1.6e-202 camS S sex pheromone
NPHDNIAI_00458 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NPHDNIAI_00459 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NPHDNIAI_00460 1.1e-209 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NPHDNIAI_00461 2.3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NPHDNIAI_00462 3e-113 acmC 3.2.1.96 NU mannosyl-glycoprotein
NPHDNIAI_00463 8e-140 IQ reductase
NPHDNIAI_00464 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
NPHDNIAI_00465 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NPHDNIAI_00466 5.5e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NPHDNIAI_00467 9.8e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPHDNIAI_00468 3.3e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPHDNIAI_00469 4.2e-139 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPHDNIAI_00470 1.1e-62 rplQ J Ribosomal protein L17
NPHDNIAI_00471 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPHDNIAI_00472 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NPHDNIAI_00473 6.2e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NPHDNIAI_00474 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NPHDNIAI_00475 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NPHDNIAI_00476 1.5e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NPHDNIAI_00477 2.6e-239 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NPHDNIAI_00478 5.8e-63 rplO J Binds to the 23S rRNA
NPHDNIAI_00479 2.9e-24 rpmD J Ribosomal protein L30
NPHDNIAI_00480 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NPHDNIAI_00481 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NPHDNIAI_00482 4.6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NPHDNIAI_00483 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NPHDNIAI_00484 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NPHDNIAI_00485 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NPHDNIAI_00486 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NPHDNIAI_00487 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NPHDNIAI_00488 1.9e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NPHDNIAI_00489 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
NPHDNIAI_00490 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NPHDNIAI_00491 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NPHDNIAI_00492 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NPHDNIAI_00493 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NPHDNIAI_00494 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NPHDNIAI_00495 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NPHDNIAI_00496 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
NPHDNIAI_00497 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NPHDNIAI_00498 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NPHDNIAI_00499 8.5e-53 S Phosphotransferase system, EIIC
NPHDNIAI_00500 1.6e-101 S Phosphotransferase system, EIIC
NPHDNIAI_00501 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NPHDNIAI_00502 8.7e-182
NPHDNIAI_00503 8.9e-62 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NPHDNIAI_00504 3.7e-70 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
NPHDNIAI_00505 4e-83 manA 5.3.1.8 G mannose-6-phosphate isomerase
NPHDNIAI_00506 1.2e-97 2.3.1.128 K acetyltransferase
NPHDNIAI_00507 1.5e-183
NPHDNIAI_00508 3.3e-17 K Transcriptional regulator, HxlR family
NPHDNIAI_00509 6e-134 K Transcriptional regulatory protein, C-terminal domain protein
NPHDNIAI_00510 4.6e-160 pstS P Phosphate
NPHDNIAI_00511 1.9e-153 pstC P probably responsible for the translocation of the substrate across the membrane
NPHDNIAI_00512 5.9e-155 pstA P Phosphate transport system permease protein PstA
NPHDNIAI_00513 3.1e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NPHDNIAI_00514 6.6e-125 phoU P Plays a role in the regulation of phosphate uptake
NPHDNIAI_00515 7.3e-134
NPHDNIAI_00516 6.5e-243 ydaM M Glycosyl transferase
NPHDNIAI_00517 2.6e-224 G Glycosyl hydrolases family 8
NPHDNIAI_00518 1.2e-94 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NPHDNIAI_00519 2.2e-35 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NPHDNIAI_00520 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
NPHDNIAI_00521 2.9e-238 ktrB P Potassium uptake protein
NPHDNIAI_00522 9.1e-116 ktrA P domain protein
NPHDNIAI_00523 1.9e-79 Q Methyltransferase
NPHDNIAI_00524 2e-231 mntH P H( )-stimulated, divalent metal cation uptake system
NPHDNIAI_00525 1.8e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NPHDNIAI_00526 4.6e-171 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NPHDNIAI_00527 2.1e-82 S NADPH-dependent FMN reductase
NPHDNIAI_00528 4e-179 MA20_14895 S Conserved hypothetical protein 698
NPHDNIAI_00529 3e-133 I alpha/beta hydrolase fold
NPHDNIAI_00530 4.2e-113 lsa S ABC transporter
NPHDNIAI_00531 1e-90 lsa S ABC transporter
NPHDNIAI_00532 1.1e-180 yfeX P Peroxidase
NPHDNIAI_00533 2e-133 arcD S C4-dicarboxylate anaerobic carrier
NPHDNIAI_00534 1.1e-124 arcD S C4-dicarboxylate anaerobic carrier
NPHDNIAI_00535 4.3e-258 ytjP 3.5.1.18 E Dipeptidase
NPHDNIAI_00536 6.3e-216 uhpT EGP Major facilitator Superfamily
NPHDNIAI_00537 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
NPHDNIAI_00538 5.3e-131 ponA V Beta-lactamase enzyme family
NPHDNIAI_00539 6e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NPHDNIAI_00540 1.9e-74
NPHDNIAI_00541 7.8e-199 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NPHDNIAI_00542 2.2e-21
NPHDNIAI_00543 9.3e-264 S Uncharacterized protein conserved in bacteria (DUF2252)
NPHDNIAI_00544 3.9e-167 L transposase, IS605 OrfB family
NPHDNIAI_00545 5e-295 L PFAM plasmid pRiA4b ORF-3 family protein
NPHDNIAI_00546 1.9e-205 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
NPHDNIAI_00547 6.6e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NPHDNIAI_00548 1.3e-157 mleR K LysR family
NPHDNIAI_00549 2.2e-304 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
NPHDNIAI_00550 4e-259 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NPHDNIAI_00551 3.4e-266 frdC 1.3.5.4 C FAD binding domain
NPHDNIAI_00552 3.5e-129 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NPHDNIAI_00553 1.3e-201 P Sodium:sulfate symporter transmembrane region
NPHDNIAI_00554 1.4e-125 citR K sugar-binding domain protein
NPHDNIAI_00555 1.2e-176 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
NPHDNIAI_00556 7.4e-149 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
NPHDNIAI_00557 8.5e-42 citD C Covalent carrier of the coenzyme of citrate lyase
NPHDNIAI_00558 3.6e-160 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
NPHDNIAI_00559 7.1e-273 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
NPHDNIAI_00560 1.3e-148 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
NPHDNIAI_00561 4.2e-112 ydjP I Alpha/beta hydrolase family
NPHDNIAI_00562 3e-159 mleR K LysR family
NPHDNIAI_00563 1.6e-252 yjjP S Putative threonine/serine exporter
NPHDNIAI_00564 3.6e-117 ung2 3.2.2.27 L Uracil-DNA glycosylase
NPHDNIAI_00565 6.5e-271 emrY EGP Major facilitator Superfamily
NPHDNIAI_00566 9.4e-186 I Alpha beta
NPHDNIAI_00567 9.8e-103 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
NPHDNIAI_00568 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NPHDNIAI_00570 4.3e-166 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
NPHDNIAI_00571 1.9e-122 S Domain of unknown function (DUF4811)
NPHDNIAI_00572 6.1e-269 lmrB EGP Major facilitator Superfamily
NPHDNIAI_00573 3.1e-72 merR K MerR HTH family regulatory protein
NPHDNIAI_00574 2.9e-57
NPHDNIAI_00575 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NPHDNIAI_00576 8.3e-221 S CAAX protease self-immunity
NPHDNIAI_00577 3.6e-109 glnP P ABC transporter permease
NPHDNIAI_00578 2.4e-110 gluC P ABC transporter permease
NPHDNIAI_00579 1.7e-151 glnH ET ABC transporter
NPHDNIAI_00580 1.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NPHDNIAI_00581 9.4e-83 usp1 T Belongs to the universal stress protein A family
NPHDNIAI_00582 8.4e-109 S VIT family
NPHDNIAI_00583 3e-114 S membrane
NPHDNIAI_00584 5.5e-164 czcD P cation diffusion facilitator family transporter
NPHDNIAI_00585 1.6e-123 sirR K iron dependent repressor
NPHDNIAI_00586 1e-30 cspC K Cold shock protein
NPHDNIAI_00587 2.6e-127 thrE S Putative threonine/serine exporter
NPHDNIAI_00588 1e-81 S Threonine/Serine exporter, ThrE
NPHDNIAI_00589 1.5e-118 lssY 3.6.1.27 I phosphatase
NPHDNIAI_00590 4.7e-08 2.3.1.128 J Acetyltransferase (GNAT) domain
NPHDNIAI_00591 4.3e-275 lysP E amino acid
NPHDNIAI_00592 2.8e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NPHDNIAI_00598 4.9e-307 lmrA 3.6.3.44 V ABC transporter
NPHDNIAI_00599 6.8e-72 K helix_turn_helix multiple antibiotic resistance protein
NPHDNIAI_00601 7.5e-96 Z012_01130 S Fic/DOC family
NPHDNIAI_00603 6.9e-156 S Polyphosphate nucleotide phosphotransferase, PPK2 family
NPHDNIAI_00604 9.1e-61
NPHDNIAI_00605 9e-207 yttB EGP Major facilitator Superfamily
NPHDNIAI_00606 1.8e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NPHDNIAI_00607 2e-74 rplI J Binds to the 23S rRNA
NPHDNIAI_00608 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NPHDNIAI_00609 2.6e-100 deoR K sugar-binding domain protein
NPHDNIAI_00610 9.1e-74 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NPHDNIAI_00611 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NPHDNIAI_00612 2.8e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NPHDNIAI_00613 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
NPHDNIAI_00614 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NPHDNIAI_00615 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NPHDNIAI_00616 1.3e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NPHDNIAI_00617 3.8e-34 yaaA S S4 domain protein YaaA
NPHDNIAI_00618 2e-203 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NPHDNIAI_00619 5.5e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NPHDNIAI_00620 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
NPHDNIAI_00621 6e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NPHDNIAI_00622 1.7e-129 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NPHDNIAI_00623 6.3e-129 jag S R3H domain protein
NPHDNIAI_00624 2.8e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NPHDNIAI_00625 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NPHDNIAI_00626 0.0 asnB 6.3.5.4 E Asparagine synthase
NPHDNIAI_00627 1.4e-289 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NPHDNIAI_00628 6.4e-248 yxbA 6.3.1.12 S ATP-grasp enzyme
NPHDNIAI_00629 2.2e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NPHDNIAI_00630 1.5e-91 2.3.1.183 M Acetyltransferase GNAT family
NPHDNIAI_00631 1.2e-244 yifK E Amino acid permease
NPHDNIAI_00632 6.9e-292 clcA P chloride
NPHDNIAI_00633 1.8e-34 secG U Preprotein translocase
NPHDNIAI_00634 2.2e-131 est 3.1.1.1 S Serine aminopeptidase, S33
NPHDNIAI_00635 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NPHDNIAI_00636 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NPHDNIAI_00637 6.3e-105 yxjI
NPHDNIAI_00638 9e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NPHDNIAI_00639 3.2e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NPHDNIAI_00640 2e-80 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
NPHDNIAI_00641 2.3e-87 K Acetyltransferase (GNAT) domain
NPHDNIAI_00642 4.4e-76 S PAS domain
NPHDNIAI_00643 2.7e-102 dnaQ 2.7.7.7 L DNA polymerase III
NPHDNIAI_00644 3e-167 murB 1.3.1.98 M Cell wall formation
NPHDNIAI_00645 6.1e-163 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NPHDNIAI_00646 5.1e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NPHDNIAI_00647 3.7e-249 fucP G Major Facilitator Superfamily
NPHDNIAI_00648 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NPHDNIAI_00649 3.8e-125 ybbR S YbbR-like protein
NPHDNIAI_00650 8.5e-254 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NPHDNIAI_00651 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NPHDNIAI_00652 5.6e-52
NPHDNIAI_00653 0.0 oatA I Acyltransferase
NPHDNIAI_00654 1.8e-78 K Transcriptional regulator
NPHDNIAI_00655 1.1e-147 XK27_02985 S Cof-like hydrolase
NPHDNIAI_00656 1.3e-76 lytE M Lysin motif
NPHDNIAI_00658 1.2e-134 K response regulator
NPHDNIAI_00659 7.6e-272 yclK 2.7.13.3 T Histidine kinase
NPHDNIAI_00660 4.1e-153 glcU U sugar transport
NPHDNIAI_00661 9.6e-96 lacA 2.3.1.79 S Transferase hexapeptide repeat
NPHDNIAI_00662 5.5e-261 pgi 5.3.1.9 G Belongs to the GPI family
NPHDNIAI_00663 1e-25
NPHDNIAI_00665 1.1e-28 xylB 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
NPHDNIAI_00666 2.7e-39
NPHDNIAI_00667 0.0 ydaO E amino acid
NPHDNIAI_00668 2.6e-302 ybeC E amino acid
NPHDNIAI_00669 5.3e-81 S Aminoacyl-tRNA editing domain
NPHDNIAI_00670 5.5e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NPHDNIAI_00671 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NPHDNIAI_00673 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NPHDNIAI_00674 0.0 uup S ABC transporter, ATP-binding protein
NPHDNIAI_00675 6.2e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NPHDNIAI_00676 1.3e-226 mtnE 2.6.1.83 E Aminotransferase
NPHDNIAI_00677 5.6e-141 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
NPHDNIAI_00678 8.4e-137 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NPHDNIAI_00679 1.2e-217 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NPHDNIAI_00680 8e-132 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NPHDNIAI_00681 2e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NPHDNIAI_00682 2.9e-99 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
NPHDNIAI_00683 9.5e-127 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
NPHDNIAI_00684 6.8e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NPHDNIAI_00685 6.4e-171 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NPHDNIAI_00686 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NPHDNIAI_00687 9.7e-283 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NPHDNIAI_00688 4.2e-133 fat 3.1.2.21 I Acyl-ACP thioesterase
NPHDNIAI_00689 7.5e-155 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NPHDNIAI_00690 1.1e-22 yabA L Involved in initiation control of chromosome replication
NPHDNIAI_00691 1.7e-182 holB 2.7.7.7 L DNA polymerase III
NPHDNIAI_00692 2.9e-51 yaaQ S Cyclic-di-AMP receptor
NPHDNIAI_00693 3.8e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NPHDNIAI_00694 2.8e-38 S Protein of unknown function (DUF2508)
NPHDNIAI_00695 5.3e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NPHDNIAI_00696 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NPHDNIAI_00697 4.3e-285 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NPHDNIAI_00698 2.6e-264 yfnA E amino acid
NPHDNIAI_00699 1.8e-85 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NPHDNIAI_00700 9.3e-158 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NPHDNIAI_00702 7.7e-203 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NPHDNIAI_00703 0.0 helD 3.6.4.12 L DNA helicase
NPHDNIAI_00704 6.3e-81 ndk 2.7.4.6 F Belongs to the NDK family
NPHDNIAI_00705 1e-181 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
NPHDNIAI_00706 7.7e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
NPHDNIAI_00707 2.1e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NPHDNIAI_00708 1.8e-226 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
NPHDNIAI_00709 4.2e-175
NPHDNIAI_00710 1.5e-129 cobB K SIR2 family
NPHDNIAI_00712 3.8e-159 yunF F Protein of unknown function DUF72
NPHDNIAI_00713 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NPHDNIAI_00714 1.8e-153 tatD L hydrolase, TatD family
NPHDNIAI_00715 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NPHDNIAI_00716 3e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NPHDNIAI_00717 6.8e-37 veg S Biofilm formation stimulator VEG
NPHDNIAI_00718 3.1e-161 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NPHDNIAI_00719 6.2e-168 znuA P Belongs to the bacterial solute-binding protein 9 family
NPHDNIAI_00720 1.4e-121 fhuC P ABC transporter
NPHDNIAI_00721 8e-127 znuB U ABC 3 transport family
NPHDNIAI_00722 9e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
NPHDNIAI_00723 7e-240 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NPHDNIAI_00724 1.1e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NPHDNIAI_00725 9e-48
NPHDNIAI_00726 2.3e-145 yxeH S hydrolase
NPHDNIAI_00727 1e-270 ywfO S HD domain protein
NPHDNIAI_00728 3.4e-149 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
NPHDNIAI_00729 1.7e-130 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
NPHDNIAI_00730 3.6e-99 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
NPHDNIAI_00731 3e-156 rssA S Phospholipase, patatin family
NPHDNIAI_00732 9.4e-118 L Integrase
NPHDNIAI_00733 4.2e-153 EG EamA-like transporter family
NPHDNIAI_00734 9.6e-129 narI 1.7.5.1 C Nitrate reductase
NPHDNIAI_00735 8.7e-99 narJ C nitrate reductase molybdenum cofactor assembly chaperone
NPHDNIAI_00736 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
NPHDNIAI_00737 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NPHDNIAI_00738 1.8e-184 moeB 2.7.7.73, 2.7.7.80 H ThiF family
NPHDNIAI_00739 5.2e-84 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
NPHDNIAI_00740 8.2e-224 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
NPHDNIAI_00741 2e-75 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
NPHDNIAI_00742 1.2e-95 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NPHDNIAI_00743 2.6e-43
NPHDNIAI_00744 5.1e-190 comP 2.7.13.3 F Sensor histidine kinase
NPHDNIAI_00745 2.3e-116 nreC K PFAM regulatory protein LuxR
NPHDNIAI_00746 1.6e-18
NPHDNIAI_00747 1.4e-181
NPHDNIAI_00748 5.1e-154 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
NPHDNIAI_00749 1.5e-217 narK P Transporter, major facilitator family protein
NPHDNIAI_00750 3.9e-32 moaD 2.8.1.12 H ThiS family
NPHDNIAI_00751 3.5e-62 moaE 2.8.1.12 H MoaE protein
NPHDNIAI_00752 2.5e-77 S Flavodoxin
NPHDNIAI_00753 4.6e-129 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPHDNIAI_00754 5e-134 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
NPHDNIAI_00755 5.3e-176 fecB P Periplasmic binding protein
NPHDNIAI_00756 9.8e-172
NPHDNIAI_00757 5.6e-74
NPHDNIAI_00758 1.3e-137 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NPHDNIAI_00759 2.4e-147 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NPHDNIAI_00760 4.7e-117 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NPHDNIAI_00761 1e-96 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NPHDNIAI_00762 3.5e-132 arsB 1.20.4.1 P Sodium Bile acid symporter family
NPHDNIAI_00763 8.2e-72 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NPHDNIAI_00764 6.1e-55 cadX K Bacterial regulatory protein, arsR family
NPHDNIAI_00765 6.2e-95 cadD P Cadmium resistance transporter
NPHDNIAI_00766 1.1e-13 K Transcriptional
NPHDNIAI_00767 4.5e-51 L Integrase
NPHDNIAI_00768 1e-28 WQ51_00220 K Helix-turn-helix domain
NPHDNIAI_00769 6e-98 S Protein of unknown function (DUF3278)
NPHDNIAI_00770 1.7e-73 M PFAM NLP P60 protein
NPHDNIAI_00771 4.1e-181 ABC-SBP S ABC transporter
NPHDNIAI_00772 1.1e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
NPHDNIAI_00773 4.8e-137 XK27_08845 S ABC transporter, ATP-binding protein
NPHDNIAI_00774 7.4e-95 P Cadmium resistance transporter
NPHDNIAI_00775 9.9e-55 K Transcriptional regulator, ArsR family
NPHDNIAI_00776 3.9e-235 mepA V MATE efflux family protein
NPHDNIAI_00777 1.5e-55 trxA O Belongs to the thioredoxin family
NPHDNIAI_00778 7.3e-130 terC P membrane
NPHDNIAI_00779 1.8e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NPHDNIAI_00780 2.8e-168 corA P CorA-like Mg2+ transporter protein
NPHDNIAI_00781 4.3e-280 pipD E Dipeptidase
NPHDNIAI_00782 1.4e-240 pbuX F xanthine permease
NPHDNIAI_00783 2.7e-250 nhaC C Na H antiporter NhaC
NPHDNIAI_00784 2.5e-184 S C4-dicarboxylate anaerobic carrier
NPHDNIAI_00785 6.7e-67 S C4-dicarboxylate anaerobic carrier
NPHDNIAI_00786 1.3e-70 IQ Enoyl-(Acyl carrier protein) reductase
NPHDNIAI_00787 3e-35 K Bacterial transcriptional regulator
NPHDNIAI_00788 8e-125 pgm3 3.1.3.73 G phosphoglycerate mutase family
NPHDNIAI_00789 1.2e-39
NPHDNIAI_00790 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NPHDNIAI_00791 8.4e-207 gldA 1.1.1.6 C dehydrogenase
NPHDNIAI_00792 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NPHDNIAI_00793 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NPHDNIAI_00794 4.3e-172 malR K Transcriptional regulator, LacI family
NPHDNIAI_00795 5.7e-214 phbA 2.3.1.9 I Belongs to the thiolase family
NPHDNIAI_00796 1.1e-256 malT G Major Facilitator
NPHDNIAI_00797 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
NPHDNIAI_00798 5.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
NPHDNIAI_00799 1e-71
NPHDNIAI_00800 3.7e-87 2.7.6.5 T Region found in RelA / SpoT proteins
NPHDNIAI_00801 3.3e-118 K response regulator
NPHDNIAI_00802 3.1e-226 sptS 2.7.13.3 T Histidine kinase
NPHDNIAI_00803 1.4e-215 yfeO P Voltage gated chloride channel
NPHDNIAI_00804 1.6e-257 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
NPHDNIAI_00805 6.6e-136 puuD S peptidase C26
NPHDNIAI_00806 5.9e-168 yvgN C Aldo keto reductase
NPHDNIAI_00807 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
NPHDNIAI_00808 3e-87 hmpT S ECF-type riboflavin transporter, S component
NPHDNIAI_00809 1.7e-262 nox C NADH oxidase
NPHDNIAI_00810 1.7e-176 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NPHDNIAI_00811 5.9e-201 XK27_09615 S reductase
NPHDNIAI_00812 2.1e-100 nqr 1.5.1.36 S reductase
NPHDNIAI_00813 5.9e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NPHDNIAI_00814 1.1e-173 K Transcriptional regulator, LacI family
NPHDNIAI_00815 6.1e-260 G Major Facilitator
NPHDNIAI_00816 4.8e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NPHDNIAI_00817 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NPHDNIAI_00818 1.3e-54 G Major Facilitator
NPHDNIAI_00819 2.2e-176 G Major Facilitator
NPHDNIAI_00820 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
NPHDNIAI_00821 1.1e-271 M protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
NPHDNIAI_00822 1.4e-270 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
NPHDNIAI_00823 6.4e-266 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
NPHDNIAI_00824 8.3e-72
NPHDNIAI_00825 3.4e-74 K Transcriptional regulator, TetR family
NPHDNIAI_00826 2.1e-12 K Transcriptional regulator, TetR family
NPHDNIAI_00827 1.1e-13 steT_1 E amino acid
NPHDNIAI_00829 4.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NPHDNIAI_00830 6.9e-83
NPHDNIAI_00831 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NPHDNIAI_00832 9.9e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NPHDNIAI_00833 1.9e-111 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
NPHDNIAI_00834 0.0 cadA P P-type ATPase
NPHDNIAI_00835 2.4e-220 5.4.2.7 G Metalloenzyme superfamily
NPHDNIAI_00837 1.6e-35 1.6.5.2 GM NAD(P)H-binding
NPHDNIAI_00838 2.5e-95
NPHDNIAI_00839 2.6e-52 S Sugar efflux transporter for intercellular exchange
NPHDNIAI_00840 1.9e-245 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
NPHDNIAI_00842 0.0 L Helicase C-terminal domain protein
NPHDNIAI_00843 1.6e-64 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
NPHDNIAI_00844 4.1e-178 S Aldo keto reductase
NPHDNIAI_00846 8.5e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NPHDNIAI_00847 2.9e-27 psiE S Phosphate-starvation-inducible E
NPHDNIAI_00848 5.9e-97 ydeN S Serine hydrolase
NPHDNIAI_00850 8.5e-182 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NPHDNIAI_00851 1.2e-253 nhaC C Na H antiporter NhaC
NPHDNIAI_00852 2.9e-37 S Cytochrome b5-like Heme/Steroid binding domain
NPHDNIAI_00853 2e-112 ywnB S NAD(P)H-binding
NPHDNIAI_00854 1.4e-36
NPHDNIAI_00855 4.3e-127 IQ Dehydrogenase reductase
NPHDNIAI_00856 1.6e-71 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
NPHDNIAI_00857 8.1e-157 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
NPHDNIAI_00858 2e-23 3.2.1.18 GH33 M Rib/alpha-like repeat
NPHDNIAI_00859 4.6e-64 S Alpha beta hydrolase
NPHDNIAI_00860 2.3e-43 S Alpha beta hydrolase
NPHDNIAI_00861 2.4e-215 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NPHDNIAI_00862 1.7e-97
NPHDNIAI_00864 1.3e-122 yciB M ErfK YbiS YcfS YnhG
NPHDNIAI_00865 3.6e-260 S Putative peptidoglycan binding domain
NPHDNIAI_00866 3.9e-108 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
NPHDNIAI_00867 1.6e-67
NPHDNIAI_00868 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
NPHDNIAI_00869 4e-215 yttB EGP Major facilitator Superfamily
NPHDNIAI_00870 8.2e-103
NPHDNIAI_00871 3.9e-24
NPHDNIAI_00872 1.8e-173 scrR K Transcriptional regulator, LacI family
NPHDNIAI_00873 4.2e-234 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NPHDNIAI_00874 6e-32 czrA K Transcriptional regulator, ArsR family
NPHDNIAI_00875 2.5e-36
NPHDNIAI_00876 0.0 yhcA V ABC transporter, ATP-binding protein
NPHDNIAI_00877 1.3e-117 devA 3.6.3.25 V ABC transporter, ATP-binding protein
NPHDNIAI_00878 3.3e-168 hrtB V ABC transporter permease
NPHDNIAI_00879 3.7e-85 ygfC K transcriptional regulator (TetR family)
NPHDNIAI_00880 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
NPHDNIAI_00881 8.9e-287 mntH P H( )-stimulated, divalent metal cation uptake system
NPHDNIAI_00883 2.8e-180 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
NPHDNIAI_00884 5.2e-156 rrmA 2.1.1.187 H Methyltransferase
NPHDNIAI_00885 3e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NPHDNIAI_00886 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NPHDNIAI_00887 1.2e-10 S Protein of unknown function (DUF4044)
NPHDNIAI_00888 2.3e-57
NPHDNIAI_00889 3.1e-77 mraZ K Belongs to the MraZ family
NPHDNIAI_00890 8.3e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NPHDNIAI_00891 1.3e-55 ftsL D Cell division protein FtsL
NPHDNIAI_00892 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NPHDNIAI_00893 2.2e-179 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NPHDNIAI_00894 2.1e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NPHDNIAI_00895 2.8e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NPHDNIAI_00896 1e-140 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NPHDNIAI_00897 2.5e-253 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NPHDNIAI_00898 3.5e-222 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NPHDNIAI_00899 3.6e-70 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NPHDNIAI_00900 3.2e-40 yggT S YGGT family
NPHDNIAI_00901 2.2e-145 ylmH S S4 domain protein
NPHDNIAI_00902 2.3e-35 divIVA D DivIVA domain protein
NPHDNIAI_00903 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NPHDNIAI_00904 4.2e-32 cspA K Cold shock protein
NPHDNIAI_00905 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
NPHDNIAI_00907 1.2e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NPHDNIAI_00908 4.6e-216 iscS 2.8.1.7 E Aminotransferase class V
NPHDNIAI_00909 7.5e-58 XK27_04120 S Putative amino acid metabolism
NPHDNIAI_00910 7.6e-224 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NPHDNIAI_00911 2.9e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
NPHDNIAI_00912 1.9e-116 S Repeat protein
NPHDNIAI_00913 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NPHDNIAI_00914 3.1e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NPHDNIAI_00915 2.3e-179 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NPHDNIAI_00916 2.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
NPHDNIAI_00917 2.6e-244 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NPHDNIAI_00918 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NPHDNIAI_00919 5.2e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NPHDNIAI_00920 6.5e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NPHDNIAI_00921 8e-140 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NPHDNIAI_00922 8.5e-218 patA 2.6.1.1 E Aminotransferase
NPHDNIAI_00923 1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NPHDNIAI_00924 8.5e-84 KT Putative sugar diacid recognition
NPHDNIAI_00925 1.1e-218 EG GntP family permease
NPHDNIAI_00926 6e-208 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NPHDNIAI_00927 2.2e-57
NPHDNIAI_00929 3.8e-130 mltD CBM50 M NlpC P60 family protein
NPHDNIAI_00930 5.7e-29
NPHDNIAI_00931 6.7e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
NPHDNIAI_00932 9.8e-32 ykzG S Belongs to the UPF0356 family
NPHDNIAI_00933 4.8e-79
NPHDNIAI_00934 1.4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NPHDNIAI_00935 2.8e-207 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
NPHDNIAI_00936 2.4e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
NPHDNIAI_00937 1.7e-222 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NPHDNIAI_00938 1.4e-275 lpdA 1.8.1.4 C Dehydrogenase
NPHDNIAI_00939 3.7e-45 yktA S Belongs to the UPF0223 family
NPHDNIAI_00940 3.8e-134 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
NPHDNIAI_00941 0.0 typA T GTP-binding protein TypA
NPHDNIAI_00942 2.7e-222 ftsW D Belongs to the SEDS family
NPHDNIAI_00943 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
NPHDNIAI_00944 3.6e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
NPHDNIAI_00945 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NPHDNIAI_00946 4.3e-197 ylbL T Belongs to the peptidase S16 family
NPHDNIAI_00947 5.8e-80 comEA L Competence protein ComEA
NPHDNIAI_00948 3.1e-89 comEB 3.5.4.12 F ComE operon protein 2
NPHDNIAI_00949 0.0 comEC S Competence protein ComEC
NPHDNIAI_00950 3.1e-147 holA 2.7.7.7 L DNA polymerase III delta subunit
NPHDNIAI_00951 2.7e-24 K helix_turn_helix, arabinose operon control protein
NPHDNIAI_00952 3.4e-187 thrC 4.2.3.1 E Threonine synthase
NPHDNIAI_00953 5.8e-172 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
NPHDNIAI_00954 7.3e-102 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NPHDNIAI_00955 4e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NPHDNIAI_00956 3.9e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NPHDNIAI_00957 8.9e-253 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NPHDNIAI_00958 2.2e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NPHDNIAI_00959 4.1e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NPHDNIAI_00960 3.6e-128 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NPHDNIAI_00961 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NPHDNIAI_00962 2e-277 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NPHDNIAI_00963 2.3e-195 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NPHDNIAI_00964 1.8e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NPHDNIAI_00965 2.3e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NPHDNIAI_00966 3.7e-243 purD 6.3.4.13 F Belongs to the GARS family
NPHDNIAI_00967 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NPHDNIAI_00968 1.8e-166
NPHDNIAI_00969 5.4e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NPHDNIAI_00970 4.3e-107 yvyE 3.4.13.9 S YigZ family
NPHDNIAI_00971 9.5e-250 comFA L Helicase C-terminal domain protein
NPHDNIAI_00972 1.1e-93 comFC S Competence protein
NPHDNIAI_00973 4.5e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NPHDNIAI_00974 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NPHDNIAI_00975 6.6e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NPHDNIAI_00976 7.7e-31 KT PspC domain protein
NPHDNIAI_00977 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
NPHDNIAI_00978 1.7e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NPHDNIAI_00979 3.2e-155 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NPHDNIAI_00980 8.5e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NPHDNIAI_00981 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NPHDNIAI_00982 1.6e-134 yrjD S LUD domain
NPHDNIAI_00983 1.3e-292 lutB C 4Fe-4S dicluster domain
NPHDNIAI_00984 2.7e-168 lutA C Cysteine-rich domain
NPHDNIAI_00985 8.6e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NPHDNIAI_00986 1.8e-204 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NPHDNIAI_00987 2.9e-162 aatB ET PFAM extracellular solute-binding protein, family 3
NPHDNIAI_00988 7.2e-89 ykhA 3.1.2.20 I Thioesterase superfamily
NPHDNIAI_00989 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NPHDNIAI_00990 9e-09 L Transposase
NPHDNIAI_00991 2.1e-24
NPHDNIAI_00992 9.5e-59
NPHDNIAI_00993 1.3e-70
NPHDNIAI_00994 9.3e-32
NPHDNIAI_00995 9.8e-152 3.1.3.73 G Belongs to the phosphoglycerate mutase family
NPHDNIAI_00996 4.7e-123 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NPHDNIAI_00997 3.1e-101 fic D Fic/DOC family
NPHDNIAI_00998 2.8e-70
NPHDNIAI_00999 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
NPHDNIAI_01000 2e-17 L nuclease
NPHDNIAI_01001 0.0 sbcC L Putative exonuclease SbcCD, C subunit
NPHDNIAI_01002 1.2e-205 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NPHDNIAI_01003 5.3e-144 ywqE 3.1.3.48 GM PHP domain protein
NPHDNIAI_01004 0.0 snf 2.7.11.1 KL domain protein
NPHDNIAI_01006 5.9e-30
NPHDNIAI_01007 7.1e-08 T Toxin-antitoxin system, toxin component, MazF family
NPHDNIAI_01008 2.5e-07 T Toxin-antitoxin system, toxin component, MazF family
NPHDNIAI_01009 2.5e-217 L Transposase
NPHDNIAI_01010 2.3e-99 epsB M biosynthesis protein
NPHDNIAI_01011 1.5e-106 ywqD 2.7.10.1 D Capsular exopolysaccharide family
NPHDNIAI_01012 6.4e-47 pglC M Bacterial sugar transferase
NPHDNIAI_01013 1.2e-86 GT4 G Glycosyl transferase 4-like
NPHDNIAI_01014 1.8e-67 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
NPHDNIAI_01015 4.6e-41 M cog cog1442
NPHDNIAI_01017 1.3e-72 cps2I S Psort location CytoplasmicMembrane, score
NPHDNIAI_01018 2.3e-35 M Glycosyltransferase sugar-binding region containing DXD motif
NPHDNIAI_01019 2.1e-28 2.7.8.12 M Glycosyltransferase, group 2 family protein
NPHDNIAI_01020 8.5e-30 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NPHDNIAI_01021 1.4e-49 S Glycosyltransferase, group 2 family protein
NPHDNIAI_01023 6.9e-30 S Acyltransferase family
NPHDNIAI_01024 0.0 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
NPHDNIAI_01025 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NPHDNIAI_01026 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NPHDNIAI_01027 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NPHDNIAI_01028 1.7e-106 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
NPHDNIAI_01029 3e-199 ykiI
NPHDNIAI_01030 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPHDNIAI_01031 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPHDNIAI_01032 1e-110 K Bacterial regulatory proteins, tetR family
NPHDNIAI_01033 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NPHDNIAI_01034 4.4e-77 ctsR K Belongs to the CtsR family
NPHDNIAI_01035 2.1e-196 adhP 1.1.1.1 C alcohol dehydrogenase
NPHDNIAI_01036 1.1e-150 S Hydrolases of the alpha beta superfamily
NPHDNIAI_01037 1e-23
NPHDNIAI_01038 3.1e-101 V VanZ like family
NPHDNIAI_01039 7.7e-231 cycA E Amino acid permease
NPHDNIAI_01040 2.8e-84 perR P Belongs to the Fur family
NPHDNIAI_01041 7.9e-258 EGP Major facilitator Superfamily
NPHDNIAI_01042 1.3e-91 tag 3.2.2.20 L glycosylase
NPHDNIAI_01043 1.9e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NPHDNIAI_01044 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NPHDNIAI_01045 2.9e-41
NPHDNIAI_01046 1.2e-302 ytgP S Polysaccharide biosynthesis protein
NPHDNIAI_01047 5.9e-152 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NPHDNIAI_01048 7.4e-277 pepV 3.5.1.18 E dipeptidase PepV
NPHDNIAI_01049 7.3e-86 uspA T Belongs to the universal stress protein A family
NPHDNIAI_01050 3.2e-176 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NPHDNIAI_01051 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
NPHDNIAI_01052 2.5e-112
NPHDNIAI_01053 7.4e-186 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
NPHDNIAI_01054 1.4e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NPHDNIAI_01055 4.9e-176 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
NPHDNIAI_01056 2.5e-103 T Ion transport 2 domain protein
NPHDNIAI_01057 0.0 S Bacterial membrane protein YfhO
NPHDNIAI_01058 3.4e-206 G Transporter, major facilitator family protein
NPHDNIAI_01059 7.1e-109 yvrI K sigma factor activity
NPHDNIAI_01060 1.1e-59 ydiI Q Thioesterase superfamily
NPHDNIAI_01061 2.9e-156 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NPHDNIAI_01062 5.7e-269 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NPHDNIAI_01063 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
NPHDNIAI_01064 2.8e-31 feoA P FeoA domain
NPHDNIAI_01065 1.9e-144 sufC O FeS assembly ATPase SufC
NPHDNIAI_01066 1.7e-240 sufD O FeS assembly protein SufD
NPHDNIAI_01067 5.2e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NPHDNIAI_01068 3.6e-79 nifU C SUF system FeS assembly protein, NifU family
NPHDNIAI_01069 1.2e-271 sufB O assembly protein SufB
NPHDNIAI_01070 2.8e-57 yitW S Iron-sulfur cluster assembly protein
NPHDNIAI_01071 2e-158 hipB K Helix-turn-helix
NPHDNIAI_01073 9.1e-123 O Holliday junction DNA helicase ruvB N-terminus
NPHDNIAI_01074 3.4e-223 O Subtilase family
NPHDNIAI_01075 3.1e-49
NPHDNIAI_01076 2.3e-74 S MTH538 TIR-like domain (DUF1863)
NPHDNIAI_01077 1.7e-30
NPHDNIAI_01078 5.9e-19 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
NPHDNIAI_01080 1.9e-22 QT PucR C-terminal helix-turn-helix domain
NPHDNIAI_01081 2.2e-131 1.6.5.2 GM NAD(P)H-binding
NPHDNIAI_01083 5.5e-29 S Protein of unknown function (DUF4065)
NPHDNIAI_01084 5.8e-88 doc
NPHDNIAI_01085 1.8e-09
NPHDNIAI_01087 1.9e-44
NPHDNIAI_01088 4e-170 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
NPHDNIAI_01089 4.5e-250 mmuP E amino acid
NPHDNIAI_01090 4.5e-91 L transposase IS116 IS110 IS902 family protein
NPHDNIAI_01091 3.8e-70 yqeY S YqeY-like protein
NPHDNIAI_01092 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NPHDNIAI_01093 1.1e-262 glnPH2 P ABC transporter permease
NPHDNIAI_01094 3.8e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NPHDNIAI_01095 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NPHDNIAI_01096 1.2e-165 yniA G Phosphotransferase enzyme family
NPHDNIAI_01097 1.9e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NPHDNIAI_01098 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NPHDNIAI_01099 9.4e-50
NPHDNIAI_01100 6.7e-128 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NPHDNIAI_01101 3.1e-178 prmA J Ribosomal protein L11 methyltransferase
NPHDNIAI_01102 7.5e-58
NPHDNIAI_01103 1.2e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NPHDNIAI_01105 1.8e-198 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
NPHDNIAI_01106 5e-273 pipD E Dipeptidase
NPHDNIAI_01109 4e-191 L Transposase IS66 family
NPHDNIAI_01110 3.4e-53 XK27_01125 L PFAM IS66 Orf2 family protein
NPHDNIAI_01113 1.7e-57 XK27_01125 L PFAM IS66 Orf2 family protein
NPHDNIAI_01114 4.3e-72 L Transposase IS66 family
NPHDNIAI_01115 1.4e-97 L Transposase IS66 family
NPHDNIAI_01116 1.3e-64 L An automated process has identified a potential problem with this gene model
NPHDNIAI_01118 1.1e-145 M family 8
NPHDNIAI_01119 1.4e-168 nss M transferase activity, transferring glycosyl groups
NPHDNIAI_01120 8.1e-42 M family 8
NPHDNIAI_01121 4.1e-69 arbx M family 8
NPHDNIAI_01122 1.3e-67 arbx M family 8
NPHDNIAI_01123 9.1e-63 S glycosyl transferase family 2
NPHDNIAI_01124 1.9e-42 S glycosyl transferase family 2
NPHDNIAI_01125 1.7e-84 S Protein of unknown function (DUF1440)
NPHDNIAI_01126 3.2e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NPHDNIAI_01127 3e-212 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
NPHDNIAI_01128 8.1e-166 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NPHDNIAI_01129 9.7e-172 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
NPHDNIAI_01130 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NPHDNIAI_01131 1.5e-86 ypmB S Protein conserved in bacteria
NPHDNIAI_01132 8.1e-123 dnaD L DnaD domain protein
NPHDNIAI_01133 1.3e-160 EG EamA-like transporter family
NPHDNIAI_01134 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
NPHDNIAI_01135 8.3e-116 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NPHDNIAI_01136 3.2e-101 ypsA S Belongs to the UPF0398 family
NPHDNIAI_01137 1.2e-42 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NPHDNIAI_01138 8e-82 F Belongs to the NrdI family
NPHDNIAI_01139 1.1e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NPHDNIAI_01140 9e-71 rnhA 3.1.26.4 L Ribonuclease HI
NPHDNIAI_01141 5.6e-65 esbA S Family of unknown function (DUF5322)
NPHDNIAI_01142 1.7e-73 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NPHDNIAI_01143 5.8e-174 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NPHDNIAI_01144 1.4e-206 carA 6.3.5.5 F Belongs to the CarA family
NPHDNIAI_01145 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NPHDNIAI_01146 0.0 FbpA K Fibronectin-binding protein
NPHDNIAI_01147 2.1e-160 degV S EDD domain protein, DegV family
NPHDNIAI_01148 1.1e-89
NPHDNIAI_01149 1.4e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NPHDNIAI_01150 1.9e-155 gspA M family 8
NPHDNIAI_01151 3.1e-153 S Alpha beta hydrolase
NPHDNIAI_01152 1.5e-94 K Acetyltransferase (GNAT) domain
NPHDNIAI_01153 4.8e-64 XK27_08635 S UPF0210 protein
NPHDNIAI_01154 5.8e-159 XK27_08635 S UPF0210 protein
NPHDNIAI_01155 3.3e-166 1.1.1.346 C Aldo keto reductase
NPHDNIAI_01156 1.7e-157 K LysR substrate binding domain protein
NPHDNIAI_01157 6.7e-81 C Flavodoxin
NPHDNIAI_01158 4e-78 yphH S Cupin domain
NPHDNIAI_01159 3.8e-73 yeaL S UPF0756 membrane protein
NPHDNIAI_01160 5.8e-242 EGP Major facilitator Superfamily
NPHDNIAI_01161 5e-75 copY K Copper transport repressor CopY TcrY
NPHDNIAI_01162 8.5e-246 yhdP S Transporter associated domain
NPHDNIAI_01163 0.0 ubiB S ABC1 family
NPHDNIAI_01164 8.7e-145 S DUF218 domain
NPHDNIAI_01165 4.6e-67 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPHDNIAI_01166 1.6e-56 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NPHDNIAI_01167 4.5e-55 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NPHDNIAI_01168 0.0 uvrA3 L excinuclease ABC, A subunit
NPHDNIAI_01169 4.3e-121 S SNARE associated Golgi protein
NPHDNIAI_01170 2.3e-229 N Uncharacterized conserved protein (DUF2075)
NPHDNIAI_01171 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NPHDNIAI_01173 1.5e-253 yifK E Amino acid permease
NPHDNIAI_01174 7.2e-158 endA V DNA/RNA non-specific endonuclease
NPHDNIAI_01175 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NPHDNIAI_01176 5.2e-37 ybaN S Protein of unknown function (DUF454)
NPHDNIAI_01177 1.3e-93 L PFAM Integrase catalytic region
NPHDNIAI_01178 1.2e-80 MA20_14895 S Conserved hypothetical protein 698
NPHDNIAI_01179 3.2e-145 K LysR substrate binding domain
NPHDNIAI_01180 1.3e-96 V VanZ like family
NPHDNIAI_01181 0.0 L helicase
NPHDNIAI_01182 5.3e-14
NPHDNIAI_01183 3.6e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NPHDNIAI_01184 3.9e-218 S cog cog1373
NPHDNIAI_01185 1.7e-176 coaA 2.7.1.33 F Pantothenic acid kinase
NPHDNIAI_01186 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NPHDNIAI_01187 1.1e-158 EG EamA-like transporter family
NPHDNIAI_01188 9.6e-67 L transposase IS116 IS110 IS902 family protein
NPHDNIAI_01189 1.1e-28 S Cytochrome B5
NPHDNIAI_01190 1.5e-74 elaA S Gnat family
NPHDNIAI_01191 1.2e-120 GM NmrA-like family
NPHDNIAI_01192 1.8e-50 hxlR K Transcriptional regulator, HxlR family
NPHDNIAI_01193 1.2e-106 XK27_02070 S Nitroreductase family
NPHDNIAI_01194 4e-83 K Transcriptional regulator, HxlR family
NPHDNIAI_01195 2e-231
NPHDNIAI_01196 2.2e-210 EGP Major facilitator Superfamily
NPHDNIAI_01197 3e-256 pepC 3.4.22.40 E aminopeptidase
NPHDNIAI_01198 5.3e-60 ylbE GM NAD dependent epimerase dehydratase family protein
NPHDNIAI_01199 4.1e-43 ylbE GM NAD dependent epimerase dehydratase family protein
NPHDNIAI_01200 0.0 pepN 3.4.11.2 E aminopeptidase
NPHDNIAI_01201 1.9e-48 K Transcriptional regulator
NPHDNIAI_01202 2.3e-24 folT S ECF transporter, substrate-specific component
NPHDNIAI_01203 1.9e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
NPHDNIAI_01204 1.9e-255 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
NPHDNIAI_01205 1.3e-67 gtcA S Teichoic acid glycosylation protein
NPHDNIAI_01206 1.4e-78 fld C Flavodoxin
NPHDNIAI_01207 6.5e-167 map 3.4.11.18 E Methionine Aminopeptidase
NPHDNIAI_01208 1.3e-220 arcT 2.6.1.1 E Aminotransferase
NPHDNIAI_01209 1.4e-254 E Arginine ornithine antiporter
NPHDNIAI_01210 9e-281 yjeM E Amino Acid
NPHDNIAI_01211 1.2e-142 yihY S Belongs to the UPF0761 family
NPHDNIAI_01212 6.6e-34 S Protein of unknown function (DUF2922)
NPHDNIAI_01213 4.9e-31
NPHDNIAI_01214 4.6e-135 recX 2.4.1.337 GT4 S Regulatory protein RecX
NPHDNIAI_01215 4.3e-146 cps1D M Domain of unknown function (DUF4422)
NPHDNIAI_01216 2.5e-172 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
NPHDNIAI_01217 5e-119 rfbP 2.7.8.6 M Bacterial sugar transferase
NPHDNIAI_01218 0.0 2.7.7.6 M Peptidase family M23
NPHDNIAI_01220 7e-19 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
NPHDNIAI_01221 5.6e-110 T Transcriptional regulatory protein, C terminal
NPHDNIAI_01222 1.3e-214 T GHKL domain
NPHDNIAI_01223 7.8e-77 S Peptidase propeptide and YPEB domain
NPHDNIAI_01224 1.5e-65 lacA S transferase hexapeptide repeat
NPHDNIAI_01225 3.7e-119 S Alpha beta hydrolase
NPHDNIAI_01226 5.1e-153 tesE Q hydratase
NPHDNIAI_01227 6.6e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NPHDNIAI_01228 2.4e-160 ypuA S Protein of unknown function (DUF1002)
NPHDNIAI_01229 1.8e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
NPHDNIAI_01230 7.6e-147 K Transcriptional regulator
NPHDNIAI_01231 7.4e-115 akr5f 1.1.1.346 S reductase
NPHDNIAI_01232 4.7e-101 qorB 1.6.5.2 GM NmrA-like family
NPHDNIAI_01233 5.5e-59 yneR
NPHDNIAI_01234 7.2e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
NPHDNIAI_01235 7.9e-36 T EAL domain
NPHDNIAI_01236 7.7e-129 pnuC H nicotinamide mononucleotide transporter
NPHDNIAI_01237 5e-104 pncA Q Isochorismatase family
NPHDNIAI_01238 9.5e-264 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NPHDNIAI_01239 7.2e-127 3.6.1.13, 3.6.1.55 F NUDIX domain
NPHDNIAI_01240 1.2e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NPHDNIAI_01241 3e-159 S Phage capsid family
NPHDNIAI_01242 4.7e-42 S Phage gp6-like head-tail connector protein
NPHDNIAI_01243 1.9e-54 S Phage head-tail joining protein
NPHDNIAI_01244 1.1e-55 S Bacteriophage holin family
NPHDNIAI_01245 9.7e-20
NPHDNIAI_01246 3.8e-217 L Recombinase zinc beta ribbon domain
NPHDNIAI_01247 2.6e-150 L Recombinase
NPHDNIAI_01248 2e-22 5.1.1.13 M Asp/Glu/Hydantoin racemase
NPHDNIAI_01249 3.2e-48 5.1.1.13 M Asp/Glu/Hydantoin racemase
NPHDNIAI_01250 3.1e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
NPHDNIAI_01251 1.2e-112 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
NPHDNIAI_01252 1.2e-94 dps P Belongs to the Dps family
NPHDNIAI_01253 7.9e-35 copZ C Heavy-metal-associated domain
NPHDNIAI_01254 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
NPHDNIAI_01255 2.4e-134 G Peptidase_C39 like family
NPHDNIAI_01256 1.8e-24
NPHDNIAI_01257 9.5e-219 glf 5.4.99.9 M UDP-galactopyranose mutase
NPHDNIAI_01258 1.5e-208 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
NPHDNIAI_01259 4.7e-76 M transferase activity, transferring glycosyl groups
NPHDNIAI_01260 1.1e-87 cps3F
NPHDNIAI_01261 1.7e-28 M biosynthesis protein
NPHDNIAI_01262 2.4e-77 rgpB GT2 M Glycosyl transferase family 2
NPHDNIAI_01263 4.4e-66 S Glycosyltransferase like family
NPHDNIAI_01264 1.1e-79 glfT1 1.1.1.133 S Glycosyltransferase like family 2
NPHDNIAI_01265 4e-73 S Acyltransferase family
NPHDNIAI_01266 1e-79
NPHDNIAI_01267 2.7e-145 rfbJ M Glycosyl transferase family 2
NPHDNIAI_01268 3.6e-13
NPHDNIAI_01269 2.4e-72 L transposase and inactivated derivatives, IS30 family
NPHDNIAI_01270 2.8e-142
NPHDNIAI_01271 9.8e-79 L Resolvase, N terminal domain
NPHDNIAI_01272 1.3e-10 L Resolvase, N terminal domain
NPHDNIAI_01273 6.3e-13 dnaQ 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NPHDNIAI_01277 1.4e-119 L hmm pf00665
NPHDNIAI_01278 1.3e-94 L Helix-turn-helix domain
NPHDNIAI_01279 1.6e-171 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NPHDNIAI_01280 5.7e-50 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NPHDNIAI_01281 7e-181 glmS2 G Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
NPHDNIAI_01282 1.7e-151 rbsK 2.7.1.15, 2.7.1.184, 2.7.1.4 G pfkB family carbohydrate kinase
NPHDNIAI_01283 3.1e-125 frlR K UTRA domain
NPHDNIAI_01284 2.4e-133 3.6.3.21 E ABC transporter, ATP-binding protein
NPHDNIAI_01285 1.4e-97 arpJ P ABC transporter permease
NPHDNIAI_01286 3.7e-134 ET Bacterial periplasmic substrate-binding proteins
NPHDNIAI_01287 0.0 rafA 3.2.1.22 G alpha-galactosidase
NPHDNIAI_01288 1.3e-185 galR K Periplasmic binding protein-like domain
NPHDNIAI_01289 1.7e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
NPHDNIAI_01290 1.1e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NPHDNIAI_01291 2.5e-119 lrgB M LrgB-like family
NPHDNIAI_01292 4.1e-66 lrgA S LrgA family
NPHDNIAI_01293 6.4e-79 lytT K response regulator receiver
NPHDNIAI_01294 3e-232 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
NPHDNIAI_01295 4e-148 f42a O Band 7 protein
NPHDNIAI_01296 7.7e-255 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
NPHDNIAI_01297 2.7e-154 yitU 3.1.3.104 S hydrolase
NPHDNIAI_01298 9.2e-39 S Cytochrome B5
NPHDNIAI_01299 1.7e-114 nreC K PFAM regulatory protein LuxR
NPHDNIAI_01300 6.7e-107 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NPHDNIAI_01301 8.3e-162 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NPHDNIAI_01302 7.8e-33 MA20_43635 M Capsular polysaccharide synthesis protein
NPHDNIAI_01303 6.8e-76 GT4 M Glycosyl transferases group 1
NPHDNIAI_01304 7.9e-85 tuaB S Polysaccharide biosynthesis protein
NPHDNIAI_01305 2.5e-27 S Glycosyl transferase family 2
NPHDNIAI_01306 6.2e-30 M -O-antigen
NPHDNIAI_01307 1.7e-67 M Glycosyltransferase sugar-binding region containing DXD motif
NPHDNIAI_01308 4.6e-48 pssE S Glycosyltransferase family 28 C-terminal domain
NPHDNIAI_01309 1.1e-72 cpsF M Oligosaccharide biosynthesis protein Alg14 like
NPHDNIAI_01310 2.6e-107 rfbP M Bacterial sugar transferase
NPHDNIAI_01311 6e-116 ywqD 2.7.10.1 D Capsular exopolysaccharide family
NPHDNIAI_01312 3.9e-135 epsB M biosynthesis protein
NPHDNIAI_01313 6.8e-168 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NPHDNIAI_01314 4.7e-109 dedA S SNARE-like domain protein
NPHDNIAI_01315 3.3e-102 S Protein of unknown function (DUF1461)
NPHDNIAI_01316 9.4e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NPHDNIAI_01317 6.6e-93 yutD S Protein of unknown function (DUF1027)
NPHDNIAI_01318 1.6e-111 S Calcineurin-like phosphoesterase
NPHDNIAI_01319 1.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NPHDNIAI_01320 2.1e-143 ytxK 2.1.1.72 L N-6 DNA Methylase
NPHDNIAI_01322 1.2e-68
NPHDNIAI_01323 3.2e-41
NPHDNIAI_01324 3.4e-79 NU general secretion pathway protein
NPHDNIAI_01325 7.1e-47 comGC U competence protein ComGC
NPHDNIAI_01326 5.1e-182 comGB NU type II secretion system
NPHDNIAI_01327 4.9e-179 comGA NU Type II IV secretion system protein
NPHDNIAI_01328 5.9e-132 yebC K Transcriptional regulatory protein
NPHDNIAI_01329 2.2e-130
NPHDNIAI_01330 4.2e-181 ccpA K catabolite control protein A
NPHDNIAI_01331 1e-209 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NPHDNIAI_01336 1.3e-263 dtpT U amino acid peptide transporter
NPHDNIAI_01337 5.9e-149 yjjH S Calcineurin-like phosphoesterase
NPHDNIAI_01340 8.5e-111
NPHDNIAI_01341 1.4e-248 EGP Major facilitator Superfamily
NPHDNIAI_01342 2.3e-301 aspT P Predicted Permease Membrane Region
NPHDNIAI_01343 8.2e-131 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NPHDNIAI_01344 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
NPHDNIAI_01345 3.1e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NPHDNIAI_01346 5.7e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NPHDNIAI_01347 0.0 yhgF K Tex-like protein N-terminal domain protein
NPHDNIAI_01348 8.1e-84 ydcK S Belongs to the SprT family
NPHDNIAI_01350 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
NPHDNIAI_01351 8.5e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
NPHDNIAI_01352 0.0 S Bacterial membrane protein, YfhO
NPHDNIAI_01353 3e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NPHDNIAI_01354 4.5e-168 I alpha/beta hydrolase fold
NPHDNIAI_01355 1.1e-214 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NPHDNIAI_01356 3.2e-119 tcyB E ABC transporter
NPHDNIAI_01357 8.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NPHDNIAI_01358 1.8e-139 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NPHDNIAI_01359 6.6e-267 pepC 3.4.22.40 E Peptidase C1-like family
NPHDNIAI_01360 1.3e-125 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NPHDNIAI_01361 1.9e-49 HA62_12640 S GCN5-related N-acetyl-transferase
NPHDNIAI_01362 7.3e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
NPHDNIAI_01363 1.6e-252 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NPHDNIAI_01364 1.4e-204 yacL S domain protein
NPHDNIAI_01365 3.9e-270 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NPHDNIAI_01366 1.4e-69 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NPHDNIAI_01367 4.7e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NPHDNIAI_01368 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NPHDNIAI_01369 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NPHDNIAI_01370 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
NPHDNIAI_01371 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NPHDNIAI_01372 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NPHDNIAI_01373 5.6e-225 aadAT EK Aminotransferase, class I
NPHDNIAI_01374 1.2e-74 M Glycosyl transferase family group 2
NPHDNIAI_01375 9e-136 M Glycosyl transferase family group 2
NPHDNIAI_01376 1.4e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NPHDNIAI_01377 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NPHDNIAI_01378 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NPHDNIAI_01379 3.4e-48
NPHDNIAI_01381 2.2e-21 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NPHDNIAI_01382 1.8e-23 K transcriptional regulator PadR family
NPHDNIAI_01383 3.2e-38 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NPHDNIAI_01384 4.3e-32 K transcriptional regulator PadR family
NPHDNIAI_01385 3.2e-83 XK27_06920 S Protein of unknown function (DUF1700)
NPHDNIAI_01386 1.3e-131 S Putative adhesin
NPHDNIAI_01387 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NPHDNIAI_01388 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NPHDNIAI_01389 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NPHDNIAI_01390 3.4e-35 nrdH O Glutaredoxin
NPHDNIAI_01391 1e-87 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NPHDNIAI_01392 3.6e-182 iunH2 3.2.2.1 F nucleoside hydrolase
NPHDNIAI_01393 9.8e-183 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
NPHDNIAI_01394 1.3e-34 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NPHDNIAI_01395 7e-46 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NPHDNIAI_01396 6.8e-36 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NPHDNIAI_01397 1.3e-114 gph 3.1.3.18 S HAD hydrolase, family IA, variant
NPHDNIAI_01398 2.2e-177 yagE E amino acid
NPHDNIAI_01399 4.6e-52 yagE E amino acid
NPHDNIAI_01400 3.4e-85 dps P Belongs to the Dps family
NPHDNIAI_01401 0.0 pacL 3.6.3.8 P P-type ATPase
NPHDNIAI_01402 5.6e-177 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
NPHDNIAI_01403 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NPHDNIAI_01404 2e-76 hsp O Belongs to the small heat shock protein (HSP20) family
NPHDNIAI_01405 5.3e-153 yeaE S Aldo keto
NPHDNIAI_01406 1.5e-236 preA 1.3.1.1 C 4Fe-4S dicluster domain
NPHDNIAI_01407 9.5e-236 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
NPHDNIAI_01408 3.9e-147 xth 3.1.11.2 L exodeoxyribonuclease III
NPHDNIAI_01409 1.2e-86 lytE M LysM domain protein
NPHDNIAI_01410 0.0 oppD EP Psort location Cytoplasmic, score
NPHDNIAI_01411 2e-42 lytE M LysM domain protein
NPHDNIAI_01412 9.8e-158 sufD O Uncharacterized protein family (UPF0051)
NPHDNIAI_01413 9.9e-111 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NPHDNIAI_01414 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NPHDNIAI_01415 5.7e-90 L Integrase
NPHDNIAI_01417 0.0 LV site-specific DNA-methyltransferase (adenine-specific) activity
NPHDNIAI_01419 5.3e-10
NPHDNIAI_01420 2e-61 soj D AAA domain
NPHDNIAI_01422 4.5e-20 S Psort location Cytoplasmic, score 8.87
NPHDNIAI_01424 4e-117 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NPHDNIAI_01425 7.2e-128 tesE Q hydratase
NPHDNIAI_01427 1.5e-129 K response regulator
NPHDNIAI_01428 0.0 vicK 2.7.13.3 T Histidine kinase
NPHDNIAI_01429 2.4e-245 yycH S YycH protein
NPHDNIAI_01430 7.8e-149 yycI S YycH protein
NPHDNIAI_01431 2.3e-153 vicX 3.1.26.11 S domain protein
NPHDNIAI_01432 1.6e-214 htrA 3.4.21.107 O serine protease
NPHDNIAI_01433 2.3e-84 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
NPHDNIAI_01434 6.5e-179 ABC-SBP S ABC transporter
NPHDNIAI_01435 4.7e-88 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NPHDNIAI_01437 2.9e-96 S reductase
NPHDNIAI_01438 4.9e-226 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
NPHDNIAI_01439 3e-201 xerS L Belongs to the 'phage' integrase family
NPHDNIAI_01441 2.3e-69 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NPHDNIAI_01442 1.2e-76 marR K Transcriptional regulator, MarR family
NPHDNIAI_01443 7.9e-169 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NPHDNIAI_01444 1.4e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NPHDNIAI_01445 2.9e-152 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
NPHDNIAI_01446 1.2e-124 IQ reductase
NPHDNIAI_01447 4.1e-223 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NPHDNIAI_01448 2e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NPHDNIAI_01449 8.6e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NPHDNIAI_01450 1.6e-255 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
NPHDNIAI_01451 1.9e-142 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NPHDNIAI_01452 9.2e-136 accA 2.1.3.15, 6.4.1.2 I alpha subunit
NPHDNIAI_01453 4.3e-130 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NPHDNIAI_01462 1.6e-244 steT E amino acid
NPHDNIAI_01463 4.9e-162 rapZ S Displays ATPase and GTPase activities
NPHDNIAI_01464 2.1e-185 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NPHDNIAI_01465 1.5e-169 whiA K May be required for sporulation
NPHDNIAI_01467 8.8e-15
NPHDNIAI_01468 1.5e-71 glpT G Major Facilitator Superfamily
NPHDNIAI_01469 2.4e-131 glpT G Major Facilitator Superfamily
NPHDNIAI_01470 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NPHDNIAI_01472 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NPHDNIAI_01473 1.2e-227 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NPHDNIAI_01474 1.8e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NPHDNIAI_01475 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NPHDNIAI_01476 1.4e-181 secY2 U SecY translocase
NPHDNIAI_01477 8.1e-224 asp1 S Accessory Sec system protein Asp1
NPHDNIAI_01478 6.2e-243 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
NPHDNIAI_01479 2.2e-16 asp3 S Accessory Sec secretory system ASP3
NPHDNIAI_01480 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NPHDNIAI_01482 8.2e-282 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NPHDNIAI_01483 4.2e-261 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NPHDNIAI_01484 7.8e-22 L Phage integrase, N-terminal SAM-like domain
NPHDNIAI_01485 1.4e-127 oxlT P Major Facilitator Superfamily
NPHDNIAI_01487 4.3e-124 L Belongs to the 'phage' integrase family
NPHDNIAI_01488 4.2e-13
NPHDNIAI_01489 8.8e-58
NPHDNIAI_01493 1e-66 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
NPHDNIAI_01494 4.1e-37
NPHDNIAI_01495 0.0 L Type III restriction enzyme, res subunit
NPHDNIAI_01497 3.3e-39 ykuJ S Protein of unknown function (DUF1797)
NPHDNIAI_01498 1.3e-177 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NPHDNIAI_01499 2.2e-198 cpoA GT4 M Glycosyltransferase, group 1 family protein
NPHDNIAI_01500 3.6e-227 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
NPHDNIAI_01501 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NPHDNIAI_01502 2.7e-39 ptsH G phosphocarrier protein HPR
NPHDNIAI_01503 6.4e-27
NPHDNIAI_01504 0.0 clpE O Belongs to the ClpA ClpB family
NPHDNIAI_01505 1.7e-100 S Pfam:DUF3816
NPHDNIAI_01506 6.8e-141 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
NPHDNIAI_01507 7.1e-116
NPHDNIAI_01508 1.2e-143 V ABC transporter, ATP-binding protein
NPHDNIAI_01509 4.7e-221 yxjG_1 E methionine synthase, vitamin-B12 independent
NPHDNIAI_01510 1.5e-143 XK27_00940 1.2.1.70, 3.5.1.9 S Putative cyclase
NPHDNIAI_01511 6.8e-159 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
NPHDNIAI_01512 3.6e-177 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NPHDNIAI_01513 0.0 lacZ 3.2.1.23 G -beta-galactosidase
NPHDNIAI_01514 0.0 lacS G Transporter
NPHDNIAI_01515 1.1e-186 lacR K Transcriptional regulator
NPHDNIAI_01516 3.3e-160 xth 3.1.11.2 L exodeoxyribonuclease III
NPHDNIAI_01517 1.2e-52 S Mazg nucleotide pyrophosphohydrolase
NPHDNIAI_01518 8.5e-34
NPHDNIAI_01519 1.3e-145 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
NPHDNIAI_01520 6.5e-64 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NPHDNIAI_01521 5.8e-74 gpm 3.1.3.73, 5.4.2.12 G Belongs to the phosphoglycerate mutase family
NPHDNIAI_01522 2.2e-118 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
NPHDNIAI_01523 1.6e-76 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Cobinamide kinase / cobinamide phosphate guanyltransferase
NPHDNIAI_01524 1.1e-239 hemL 5.4.3.8 H Aminotransferase class-III
NPHDNIAI_01525 2.8e-174 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
NPHDNIAI_01526 2.6e-137 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NPHDNIAI_01527 1.7e-192 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NPHDNIAI_01528 7e-59 cysG 1.3.1.76, 4.99.1.4 H Putative NAD(P)-binding
NPHDNIAI_01529 2.7e-240 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
NPHDNIAI_01530 7.8e-122 cbiO 2.1.1.195 P part of an ABC transporter complex. Responsible for energy coupling to the transport system
NPHDNIAI_01531 6.8e-103 cbiQ P Cobalt transport protein
NPHDNIAI_01532 7.6e-44 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
NPHDNIAI_01533 1e-123 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
NPHDNIAI_01534 8.1e-91 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Tetrapyrrole (Corrin/Porphyrin) Methylases
NPHDNIAI_01535 8.1e-108 cbiK 4.99.1.3 H Cobalt chelatase (CbiK)
NPHDNIAI_01536 3.3e-176 cobA 2.1.1.107, 4.2.1.75 H Tetrapyrrole (Corrin/Porphyrin) Methylases
NPHDNIAI_01537 2.8e-97 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H Precorrin-6x reductase CbiJ/CobK
NPHDNIAI_01538 6.6e-128 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H Tetrapyrrole (Corrin/Porphyrin) Methylases
NPHDNIAI_01539 3e-145 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
NPHDNIAI_01540 8.1e-129 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
NPHDNIAI_01541 1.4e-77 cbiT 2.1.1.132, 2.1.1.196 H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
NPHDNIAI_01542 1.6e-79 cbiE 2.1.1.132, 2.1.1.289 H Tetrapyrrole (Corrin/Porphyrin) Methylases
NPHDNIAI_01543 4.4e-187 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
NPHDNIAI_01544 9.3e-108 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
NPHDNIAI_01545 1.6e-145 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
NPHDNIAI_01546 4.3e-205 cbiA 6.3.5.11, 6.3.5.9 F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
NPHDNIAI_01547 4.7e-170 cobD 4.1.1.81 E Aminotransferase class I and II
NPHDNIAI_01548 3.2e-77 cobO 2.5.1.17 S Cobalamin adenosyltransferase
NPHDNIAI_01549 8.7e-116 XK27_04590 S NADPH-dependent FMN reductase
NPHDNIAI_01550 2.2e-73 fld C Flavodoxin
NPHDNIAI_01551 2.6e-68 eutP E Ethanolamine utilisation - propanediol utilisation
NPHDNIAI_01552 5.9e-68 P Cadmium resistance transporter
NPHDNIAI_01553 1.9e-75 pgm1 3.1.3.73 G phosphoglycerate mutase
NPHDNIAI_01554 1.1e-115 3.1.3.48 T Pfam:Y_phosphatase3C
NPHDNIAI_01555 3e-54 pduU E BMC
NPHDNIAI_01556 1.9e-217 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NPHDNIAI_01557 2.1e-202 pduQ C Iron-containing alcohol dehydrogenase
NPHDNIAI_01558 3.1e-262 pduP 1.2.1.87 C Aldehyde dehydrogenase family
NPHDNIAI_01559 4.5e-77 pduO S Haem-degrading
NPHDNIAI_01560 2.2e-102 pduO 2.5.1.17 S Cobalamin adenosyltransferase
NPHDNIAI_01561 5.2e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
NPHDNIAI_01562 1.3e-79 S Putative propanediol utilisation
NPHDNIAI_01563 1.9e-115 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
NPHDNIAI_01564 7.8e-40 pduA_4 CQ BMC
NPHDNIAI_01565 1.8e-56 pduK CQ BMC
NPHDNIAI_01566 2.6e-45 pduH S Dehydratase medium subunit
NPHDNIAI_01567 5.6e-309 pduG D Diol dehydratase reactivase ATPase-like domain
NPHDNIAI_01568 2.4e-71 pduE 4.2.1.28 Q Dehydratase small subunit
NPHDNIAI_01569 3.9e-125 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
NPHDNIAI_01570 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
NPHDNIAI_01571 2.7e-134 pduB E BMC
NPHDNIAI_01572 1.6e-37 pduA_4 CQ BMC
NPHDNIAI_01573 8.3e-159 K helix_turn_helix, arabinose operon control protein
NPHDNIAI_01574 3.6e-138 eutJ E Hsp70 protein
NPHDNIAI_01575 1e-133 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NPHDNIAI_01576 4.9e-160
NPHDNIAI_01577 1.3e-156 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
NPHDNIAI_01578 4.9e-167 S AI-2E family transporter
NPHDNIAI_01579 1.7e-131 XK27_07210 6.1.1.6 S B3 4 domain
NPHDNIAI_01580 2.3e-78 yybA 2.3.1.57 K Transcriptional regulator
NPHDNIAI_01581 1.1e-89 M1-874 K Domain of unknown function (DUF1836)
NPHDNIAI_01582 2.5e-89 1.14.14.47, 1.6.5.3, 1.6.99.3 GM epimerase
NPHDNIAI_01583 3.1e-153 ypdB V (ABC) transporter
NPHDNIAI_01584 1.7e-93 K Transcriptional regulator (TetR family)
NPHDNIAI_01585 5.3e-221 V domain protein
NPHDNIAI_01586 5.3e-84 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPHDNIAI_01587 6.7e-63 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPHDNIAI_01589 6.6e-35 S Transglycosylase associated protein
NPHDNIAI_01590 1.9e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NPHDNIAI_01591 5e-127 3.1.3.73 G phosphoglycerate mutase
NPHDNIAI_01592 4e-116 dedA S SNARE associated Golgi protein
NPHDNIAI_01593 0.0 helD 3.6.4.12 L DNA helicase
NPHDNIAI_01594 1.3e-36 Q pyridine nucleotide-disulphide oxidoreductase
NPHDNIAI_01595 9.3e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NPHDNIAI_01596 8.9e-41 1.3.5.4 S FMN binding
NPHDNIAI_01597 8.3e-221 norA EGP Major facilitator Superfamily
NPHDNIAI_01598 5.8e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NPHDNIAI_01599 2.8e-154 metQ1 P Belongs to the nlpA lipoprotein family
NPHDNIAI_01600 1.5e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NPHDNIAI_01601 6.9e-103 metI P ABC transporter permease
NPHDNIAI_01602 1.2e-213 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NPHDNIAI_01603 2.8e-55 clcA P chloride
NPHDNIAI_01604 3.9e-46 clcA P chloride
NPHDNIAI_01605 8.8e-215 L transposase, IS605 OrfB family
NPHDNIAI_01606 1.9e-63 L PFAM transposase IS200-family protein
NPHDNIAI_01607 1.7e-15
NPHDNIAI_01608 2.9e-33
NPHDNIAI_01609 9e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NPHDNIAI_01611 2.2e-230 yfmL L DEAD DEAH box helicase
NPHDNIAI_01612 1.7e-190 mocA S Oxidoreductase
NPHDNIAI_01613 9.1e-62 S Domain of unknown function (DUF4828)
NPHDNIAI_01614 3.6e-105 yvdD 3.2.2.10 S Belongs to the LOG family
NPHDNIAI_01615 4.5e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NPHDNIAI_01616 3.7e-298 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
NPHDNIAI_01617 1e-195 S Protein of unknown function (DUF3114)
NPHDNIAI_01618 9.3e-80 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
NPHDNIAI_01619 9.3e-119 ybhL S Belongs to the BI1 family
NPHDNIAI_01620 9.9e-71 yhjX P Major Facilitator Superfamily
NPHDNIAI_01622 2.2e-90
NPHDNIAI_01623 2.1e-290 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NPHDNIAI_01624 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NPHDNIAI_01625 3.3e-293 yjbQ P TrkA C-terminal domain protein
NPHDNIAI_01626 6.5e-273 pipD E Dipeptidase
NPHDNIAI_01627 0.0 trxB2 1.8.1.9 C Thioredoxin domain
NPHDNIAI_01628 1.2e-105 ahpC 1.11.1.15 O Peroxiredoxin
NPHDNIAI_01629 9.7e-142 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NPHDNIAI_01630 4.2e-121 sdaAB 4.3.1.17 E Serine dehydratase beta chain
NPHDNIAI_01633 2.3e-177 S FRG
NPHDNIAI_01634 9.1e-211 yfnA E Amino Acid
NPHDNIAI_01635 1.1e-87 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NPHDNIAI_01636 1.4e-54 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NPHDNIAI_01637 5e-62 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NPHDNIAI_01638 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NPHDNIAI_01639 7e-297 mco Q Multicopper oxidase
NPHDNIAI_01640 6.2e-64 gntR1 K Transcriptional regulator, GntR family
NPHDNIAI_01641 0.0 S Peptidase, M23
NPHDNIAI_01642 0.0 M NlpC/P60 family
NPHDNIAI_01643 2.2e-309 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NPHDNIAI_01644 2.3e-228 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NPHDNIAI_01645 1.1e-163 yueF S AI-2E family transporter
NPHDNIAI_01646 2.3e-29
NPHDNIAI_01647 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NPHDNIAI_01649 2.3e-91 yxiO S Vacuole effluxer Atg22 like
NPHDNIAI_01650 1.8e-55 yxiO S Vacuole effluxer Atg22 like
NPHDNIAI_01651 9.8e-30 yxiO S Vacuole effluxer Atg22 like
NPHDNIAI_01652 1.8e-51 npp S type I phosphodiesterase nucleotide pyrophosphatase
NPHDNIAI_01653 1.8e-153 npp S type I phosphodiesterase nucleotide pyrophosphatase
NPHDNIAI_01654 7.9e-32 npp S type I phosphodiesterase nucleotide pyrophosphatase
NPHDNIAI_01655 2.3e-238 E amino acid
NPHDNIAI_01656 4.8e-67 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NPHDNIAI_01657 2.8e-15 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NPHDNIAI_01659 2e-219 yxjG_1 E methionine synthase, vitamin-B12 independent
NPHDNIAI_01660 0.0 lacS G Transporter
NPHDNIAI_01661 2.3e-28
NPHDNIAI_01662 7.1e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NPHDNIAI_01663 8.3e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NPHDNIAI_01664 4.4e-190 yeaN P Transporter, major facilitator family protein
NPHDNIAI_01665 2.7e-73 S 3-demethylubiquinone-9 3-methyltransferase
NPHDNIAI_01666 2.7e-82 nrdI F Belongs to the NrdI family
NPHDNIAI_01667 4.6e-236 yhdP S Transporter associated domain
NPHDNIAI_01668 8.1e-154 KT YcbB domain
NPHDNIAI_01669 7.6e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NPHDNIAI_01670 3.3e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
NPHDNIAI_01671 5e-157 EG EamA-like transporter family
NPHDNIAI_01672 7.2e-101 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
NPHDNIAI_01673 7.6e-48 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NPHDNIAI_01674 9.2e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NPHDNIAI_01675 0.0 copA 3.6.3.54 P P-type ATPase
NPHDNIAI_01676 3.1e-86
NPHDNIAI_01678 1.8e-56
NPHDNIAI_01679 5.4e-59 yjcE P Sodium proton antiporter
NPHDNIAI_01681 0.0 L PLD-like domain
NPHDNIAI_01682 1.2e-106 L Uncharacterized conserved protein (DUF2075)
NPHDNIAI_01683 5.8e-39 yhaI S Protein of unknown function (DUF805)
NPHDNIAI_01684 2.2e-44
NPHDNIAI_01685 2.4e-22
NPHDNIAI_01686 1.6e-46
NPHDNIAI_01687 2.9e-96 K Acetyltransferase (GNAT) domain
NPHDNIAI_01688 1e-295 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
NPHDNIAI_01689 7.8e-16 gntT EG Gluconate
NPHDNIAI_01690 1.4e-186 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NPHDNIAI_01691 3.8e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NPHDNIAI_01692 7.8e-263 argH 4.3.2.1 E argininosuccinate lyase
NPHDNIAI_01693 3.8e-83 bioY S BioY family
NPHDNIAI_01694 5.4e-170 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NPHDNIAI_01695 2.2e-182 phoH T phosphate starvation-inducible protein PhoH
NPHDNIAI_01696 3.3e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NPHDNIAI_01697 3.8e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NPHDNIAI_01698 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NPHDNIAI_01699 1.4e-144 recO L Involved in DNA repair and RecF pathway recombination
NPHDNIAI_01700 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NPHDNIAI_01701 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NPHDNIAI_01702 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NPHDNIAI_01703 7.7e-208 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NPHDNIAI_01704 2.4e-220 patA 2.6.1.1 E Aminotransferase
NPHDNIAI_01705 6.2e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
NPHDNIAI_01706 6.5e-156 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NPHDNIAI_01707 6.6e-237 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NPHDNIAI_01708 2e-29 S Protein of unknown function (DUF2929)
NPHDNIAI_01709 0.0 dnaE 2.7.7.7 L DNA polymerase
NPHDNIAI_01710 3.6e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NPHDNIAI_01711 9.3e-169 cvfB S S1 domain
NPHDNIAI_01712 3.8e-162 xerD D recombinase XerD
NPHDNIAI_01713 2.8e-63 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPHDNIAI_01714 4.2e-136 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NPHDNIAI_01715 1.7e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NPHDNIAI_01716 5.9e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NPHDNIAI_01717 2.3e-99 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NPHDNIAI_01718 2.6e-194 ypbB 5.1.3.1 S Helix-turn-helix domain
NPHDNIAI_01719 9.3e-267 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
NPHDNIAI_01720 2.5e-13 M Lysin motif
NPHDNIAI_01721 7.6e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NPHDNIAI_01722 3.9e-205 rpsA 1.17.7.4 J Ribosomal protein S1
NPHDNIAI_01723 9.4e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NPHDNIAI_01724 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NPHDNIAI_01725 1.4e-234 S Tetratricopeptide repeat protein
NPHDNIAI_01726 8.2e-224 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NPHDNIAI_01727 0.0 yfmR S ABC transporter, ATP-binding protein
NPHDNIAI_01728 7.2e-191 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NPHDNIAI_01729 9.6e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NPHDNIAI_01730 1.9e-110 hlyIII S protein, hemolysin III
NPHDNIAI_01731 4.9e-151 DegV S EDD domain protein, DegV family
NPHDNIAI_01732 2.4e-167 ypmR E lipolytic protein G-D-S-L family
NPHDNIAI_01733 2.8e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
NPHDNIAI_01734 4.4e-35 yozE S Belongs to the UPF0346 family
NPHDNIAI_01735 9.2e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NPHDNIAI_01736 1.5e-138 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NPHDNIAI_01737 2.1e-160 dprA LU DNA protecting protein DprA
NPHDNIAI_01738 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NPHDNIAI_01739 2.7e-67 yqkB S Belongs to the HesB IscA family
NPHDNIAI_01740 8.6e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
NPHDNIAI_01741 8.1e-79 F NUDIX domain
NPHDNIAI_01742 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NPHDNIAI_01743 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NPHDNIAI_01744 1.2e-104 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NPHDNIAI_01745 1.4e-164 lacX 5.1.3.3 G Aldose 1-epimerase
NPHDNIAI_01746 5.7e-228 clcA_2 P Chloride transporter, ClC family
NPHDNIAI_01747 4.4e-129 L PFAM transposase IS116 IS110 IS902
NPHDNIAI_01748 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
NPHDNIAI_01749 9.3e-110 lssY 3.6.1.27 I Acid phosphatase homologues
NPHDNIAI_01750 9.1e-161 L Transposase IS66 family
NPHDNIAI_01751 4.9e-60 XK27_01125 L PFAM IS66 Orf2 family protein
NPHDNIAI_01753 1.6e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
NPHDNIAI_01754 8.6e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NPHDNIAI_01755 2.3e-111 yjbM 2.7.6.5 S RelA SpoT domain protein
NPHDNIAI_01756 5.8e-112 yjbH Q Thioredoxin
NPHDNIAI_01757 1.6e-260 pipD E Dipeptidase
NPHDNIAI_01758 9.5e-197 coiA 3.6.4.12 S Competence protein
NPHDNIAI_01759 3e-119 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NPHDNIAI_01760 1e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NPHDNIAI_01761 1.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
NPHDNIAI_01769 2.6e-15 K Cro/C1-type HTH DNA-binding domain
NPHDNIAI_01771 1.6e-169 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NPHDNIAI_01772 5.5e-45 yitW S Pfam:DUF59
NPHDNIAI_01773 1e-68 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NPHDNIAI_01774 2.3e-162 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
NPHDNIAI_01775 6.8e-50 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
NPHDNIAI_01778 8.4e-131 S amidohydrolase
NPHDNIAI_01779 1.1e-259 K Aminotransferase class I and II
NPHDNIAI_01780 4.5e-118 azlC E azaleucine resistance protein AzlC
NPHDNIAI_01781 3.2e-50 azlD E Branched-chain amino acid transport
NPHDNIAI_01782 8e-109 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
NPHDNIAI_01784 1.8e-53 S GyrI-like small molecule binding domain
NPHDNIAI_01785 7.4e-28 S GyrI-like small molecule binding domain
NPHDNIAI_01786 1.8e-104 yhiD S MgtC family
NPHDNIAI_01787 1.6e-94 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NPHDNIAI_01788 6.3e-193 V Beta-lactamase
NPHDNIAI_01789 6.9e-153 L Transposase
NPHDNIAI_01790 5.1e-116 yfbR S HD containing hydrolase-like enzyme
NPHDNIAI_01791 9.1e-14
NPHDNIAI_01792 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NPHDNIAI_01793 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NPHDNIAI_01795 2.2e-18
NPHDNIAI_01799 3.4e-18
NPHDNIAI_01800 1.6e-123 L Belongs to the 'phage' integrase family
NPHDNIAI_01801 1.9e-225 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NPHDNIAI_01802 3.8e-281 2.4.1.5 GH13 G Glycosyl hydrolase family 70
NPHDNIAI_01803 4.2e-109 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NPHDNIAI_01804 9.8e-163 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NPHDNIAI_01805 0.0 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NPHDNIAI_01806 1.9e-110
NPHDNIAI_01807 1.8e-90 L PFAM Integrase catalytic region
NPHDNIAI_01808 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NPHDNIAI_01809 8.1e-197 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NPHDNIAI_01810 0.0 dnaK O Heat shock 70 kDa protein
NPHDNIAI_01811 1.3e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NPHDNIAI_01812 5.9e-194 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NPHDNIAI_01813 7.6e-64
NPHDNIAI_01814 8.5e-176 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NPHDNIAI_01815 7.1e-164 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NPHDNIAI_01816 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NPHDNIAI_01817 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NPHDNIAI_01818 1.3e-48 ylxQ J ribosomal protein
NPHDNIAI_01819 1e-44 ylxR K Protein of unknown function (DUF448)
NPHDNIAI_01820 1.4e-215 nusA K Participates in both transcription termination and antitermination
NPHDNIAI_01821 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
NPHDNIAI_01822 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NPHDNIAI_01823 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NPHDNIAI_01824 3.7e-235 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NPHDNIAI_01825 1.7e-137 cdsA 2.7.7.41 I Belongs to the CDS family
NPHDNIAI_01826 2.4e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NPHDNIAI_01827 4.8e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NPHDNIAI_01828 4.1e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NPHDNIAI_01829 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NPHDNIAI_01830 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
NPHDNIAI_01831 5.9e-180 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPHDNIAI_01832 5.4e-49 yazA L GIY-YIG catalytic domain protein
NPHDNIAI_01833 5.4e-141 yabB 2.1.1.223 L Methyltransferase small domain
NPHDNIAI_01834 1.6e-117 plsC 2.3.1.51 I Acyltransferase
NPHDNIAI_01835 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
NPHDNIAI_01836 1.3e-35 ynzC S UPF0291 protein
NPHDNIAI_01837 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NPHDNIAI_01838 6e-208 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
NPHDNIAI_01839 4.8e-125 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NPHDNIAI_01841 2.5e-88
NPHDNIAI_01842 9.2e-92 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NPHDNIAI_01843 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NPHDNIAI_01844 1.1e-155 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NPHDNIAI_01845 3.7e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NPHDNIAI_01846 5.2e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NPHDNIAI_01847 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NPHDNIAI_01848 7.6e-09
NPHDNIAI_01849 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
NPHDNIAI_01850 1.4e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
NPHDNIAI_01851 1.8e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NPHDNIAI_01852 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NPHDNIAI_01853 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NPHDNIAI_01854 3.5e-163 S Tetratricopeptide repeat
NPHDNIAI_01855 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NPHDNIAI_01856 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NPHDNIAI_01857 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
NPHDNIAI_01858 3.3e-231 EGP Sugar (and other) transporter
NPHDNIAI_01859 1.5e-253 yfnA E Amino Acid
NPHDNIAI_01860 6.9e-74 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
NPHDNIAI_01861 1.7e-99 gmk2 2.7.4.8 F Guanylate kinase
NPHDNIAI_01862 2.1e-81 zur P Belongs to the Fur family
NPHDNIAI_01863 3.1e-17 3.2.1.14 GH18
NPHDNIAI_01864 1e-148
NPHDNIAI_01866 0.0 clpL O associated with various cellular activities
NPHDNIAI_01867 7.8e-32
NPHDNIAI_01868 1.2e-214 patA 2.6.1.1 E Aminotransferase
NPHDNIAI_01869 3.2e-173 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPHDNIAI_01870 5e-75 osmC O OsmC-like protein
NPHDNIAI_01871 9.4e-198 gntT EG Gluconate
NPHDNIAI_01872 4.9e-182 K Transcriptional regulator, LacI family
NPHDNIAI_01873 8.3e-290 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
NPHDNIAI_01874 3.9e-93
NPHDNIAI_01875 3.6e-25
NPHDNIAI_01876 3.7e-61 asp S Asp23 family, cell envelope-related function
NPHDNIAI_01877 1.2e-85 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
NPHDNIAI_01881 3.8e-159 metQ_4 P Belongs to the nlpA lipoprotein family
NPHDNIAI_01882 2.6e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NPHDNIAI_01883 1e-122 O Zinc-dependent metalloprotease
NPHDNIAI_01884 6.9e-122 L Helix-turn-helix domain
NPHDNIAI_01885 9.5e-39 S Cytochrome B5
NPHDNIAI_01886 1.7e-91
NPHDNIAI_01887 7e-121 pnb C nitroreductase
NPHDNIAI_01888 2.7e-170 XK27_00915 C Luciferase-like monooxygenase
NPHDNIAI_01889 4.3e-156 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
NPHDNIAI_01890 2e-66 S Protein of unknown function (DUF3021)
NPHDNIAI_01891 4.6e-76 K LytTr DNA-binding domain
NPHDNIAI_01892 1.8e-95 K Acetyltransferase (GNAT) family
NPHDNIAI_01895 3.1e-104 wecD3 K PFAM GCN5-related N-acetyltransferase
NPHDNIAI_01896 2.1e-282 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NPHDNIAI_01897 1e-111 frnE Q DSBA-like thioredoxin domain
NPHDNIAI_01898 8.8e-164 I alpha/beta hydrolase fold
NPHDNIAI_01899 8.5e-20 K Helix-turn-helix XRE-family like proteins
NPHDNIAI_01900 3.3e-35 S Phage derived protein Gp49-like (DUF891)
NPHDNIAI_01902 8.9e-41 yrvD S Pfam:DUF1049
NPHDNIAI_01903 3.3e-152 3.1.3.102, 3.1.3.104 S hydrolase
NPHDNIAI_01904 2.1e-90 ntd 2.4.2.6 F Nucleoside
NPHDNIAI_01905 6e-32
NPHDNIAI_01906 9.5e-18
NPHDNIAI_01907 3.6e-65
NPHDNIAI_01908 7.9e-34
NPHDNIAI_01909 1.8e-206 potD P ABC transporter
NPHDNIAI_01910 2.5e-139 potC P ABC transporter permease
NPHDNIAI_01911 1.3e-145 potB P ABC transporter permease
NPHDNIAI_01912 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NPHDNIAI_01913 3.5e-50 1.6.5.2 GM NAD(P)H-binding
NPHDNIAI_01914 3.8e-73 K Transcriptional regulator
NPHDNIAI_01915 1.6e-163 proX M ABC transporter, substrate-binding protein, QAT family
NPHDNIAI_01916 1.2e-107 proWZ P ABC transporter permease
NPHDNIAI_01917 6.5e-142 proV E ABC transporter, ATP-binding protein
NPHDNIAI_01918 2.7e-101 proW P ABC transporter, permease protein
NPHDNIAI_01919 2e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NPHDNIAI_01920 4.5e-98 dedA 3.1.3.1 S SNARE associated Golgi protein
NPHDNIAI_01921 1.6e-228 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NPHDNIAI_01922 1.4e-78 K AsnC family
NPHDNIAI_01923 1.6e-79 uspA T universal stress protein
NPHDNIAI_01924 6.8e-44 ltrA S Bacterial low temperature requirement A protein (LtrA)
NPHDNIAI_01925 2e-66 ltrA S Bacterial low temperature requirement A protein (LtrA)
NPHDNIAI_01926 1.5e-52 ywiB S Domain of unknown function (DUF1934)
NPHDNIAI_01927 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NPHDNIAI_01928 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NPHDNIAI_01929 2e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NPHDNIAI_01930 4.6e-41 rpmE2 J Ribosomal protein L31
NPHDNIAI_01931 5.4e-237 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPHDNIAI_01932 3.1e-164 S Alpha/beta hydrolase of unknown function (DUF915)
NPHDNIAI_01933 7.3e-116 srtA 3.4.22.70 M sortase family
NPHDNIAI_01934 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
NPHDNIAI_01935 1.8e-158 3.2.1.55 GH51 G Right handed beta helix region
NPHDNIAI_01936 9.8e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NPHDNIAI_01937 1.3e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
NPHDNIAI_01938 9.2e-121 pgm3 3.1.3.73 G Belongs to the phosphoglycerate mutase family
NPHDNIAI_01939 8e-87 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NPHDNIAI_01940 2e-92 lemA S LemA family
NPHDNIAI_01941 2e-158 htpX O Belongs to the peptidase M48B family
NPHDNIAI_01942 1.9e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NPHDNIAI_01943 3.6e-253 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NPHDNIAI_01944 2.7e-149 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NPHDNIAI_01945 1.4e-170 glsA 3.5.1.2 E Belongs to the glutaminase family
NPHDNIAI_01946 2.1e-254 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NPHDNIAI_01947 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPHDNIAI_01948 3.9e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
NPHDNIAI_01949 1.7e-295 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPHDNIAI_01951 3.2e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NPHDNIAI_01952 3.4e-208 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NPHDNIAI_01953 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
NPHDNIAI_01954 3.1e-251 U Belongs to the purine-cytosine permease (2.A.39) family
NPHDNIAI_01955 2.3e-242 codA 3.5.4.1 F cytosine deaminase
NPHDNIAI_01956 6.4e-145 tesE Q hydratase
NPHDNIAI_01957 6.9e-113 S (CBS) domain
NPHDNIAI_01958 1.6e-102 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NPHDNIAI_01959 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NPHDNIAI_01960 4.8e-39 yabO J S4 domain protein
NPHDNIAI_01961 2.4e-54 divIC D Septum formation initiator
NPHDNIAI_01962 2.3e-60 yabR J RNA binding
NPHDNIAI_01963 4.8e-252 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NPHDNIAI_01964 1.3e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NPHDNIAI_01965 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NPHDNIAI_01966 1.1e-169 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NPHDNIAI_01967 2.4e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NPHDNIAI_01968 1.6e-293 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NPHDNIAI_01969 3e-85
NPHDNIAI_01970 1.1e-188 EGP Major facilitator Superfamily
NPHDNIAI_01971 4.1e-69 K Transcriptional regulator, HxlR family
NPHDNIAI_01972 1.8e-94 XK27_02070 S Nitroreductase family
NPHDNIAI_01973 3.4e-169 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NPHDNIAI_01974 0.0
NPHDNIAI_01976 8.4e-31 S Domain of unknown function (DUF3173)
NPHDNIAI_01977 9.7e-225 L Belongs to the 'phage' integrase family
NPHDNIAI_01978 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NPHDNIAI_01979 4.5e-168 T Calcineurin-like phosphoesterase superfamily domain
NPHDNIAI_01980 1.8e-223 mdtG EGP Major facilitator Superfamily
NPHDNIAI_01981 4.4e-129 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NPHDNIAI_01982 3.6e-82 yvbK 3.1.3.25 K GNAT family
NPHDNIAI_01983 5.2e-248 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
NPHDNIAI_01984 5.4e-204 amtB P ammonium transporter
NPHDNIAI_01994 1.2e-97 2.3.1.128 K Acetyltransferase (GNAT) domain
NPHDNIAI_01995 2.9e-233 lmrB EGP Major facilitator Superfamily
NPHDNIAI_01996 6.1e-57
NPHDNIAI_01997 1.2e-285 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
NPHDNIAI_01998 2.2e-78 S Psort location Cytoplasmic, score
NPHDNIAI_01999 2.2e-85 S Short repeat of unknown function (DUF308)
NPHDNIAI_02000 1.4e-88 oxlT P Major Facilitator Superfamily
NPHDNIAI_02001 2.1e-160 spoU 2.1.1.185 J Methyltransferase
NPHDNIAI_02002 1.3e-91 ywlG S Belongs to the UPF0340 family
NPHDNIAI_02003 2e-18
NPHDNIAI_02004 7.5e-163 S Alpha/beta hydrolase of unknown function (DUF915)
NPHDNIAI_02005 4.7e-114 yviA S Protein of unknown function (DUF421)
NPHDNIAI_02006 4.5e-71 S Protein of unknown function (DUF3290)
NPHDNIAI_02007 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NPHDNIAI_02008 4.5e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NPHDNIAI_02009 3.4e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NPHDNIAI_02010 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NPHDNIAI_02011 5.9e-223 dnaB L replication initiation and membrane attachment
NPHDNIAI_02012 1.9e-172 dnaI L Primosomal protein DnaI
NPHDNIAI_02013 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NPHDNIAI_02014 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NPHDNIAI_02015 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NPHDNIAI_02016 7e-95 yqeG S HAD phosphatase, family IIIA
NPHDNIAI_02017 8.1e-218 yqeH S Ribosome biogenesis GTPase YqeH
NPHDNIAI_02018 1.9e-47 yhbY J RNA-binding protein
NPHDNIAI_02019 2.9e-119 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NPHDNIAI_02020 6.2e-111 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
NPHDNIAI_02021 9.3e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NPHDNIAI_02022 8.7e-136 yqeM Q Methyltransferase
NPHDNIAI_02023 2.4e-209 ylbM S Belongs to the UPF0348 family
NPHDNIAI_02024 4.9e-99 yceD S Uncharacterized ACR, COG1399
NPHDNIAI_02025 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NPHDNIAI_02026 1.5e-121 K response regulator
NPHDNIAI_02027 7e-278 arlS 2.7.13.3 T Histidine kinase
NPHDNIAI_02028 4.2e-237 yjeM E Amino Acid
NPHDNIAI_02029 1.2e-233 V MatE
NPHDNIAI_02030 5.6e-68 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NPHDNIAI_02031 4.5e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NPHDNIAI_02032 1e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NPHDNIAI_02033 1.8e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NPHDNIAI_02034 5.3e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
NPHDNIAI_02035 6.7e-59 yodB K Transcriptional regulator, HxlR family
NPHDNIAI_02036 2.3e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NPHDNIAI_02037 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NPHDNIAI_02038 5.6e-115 rlpA M PFAM NLP P60 protein
NPHDNIAI_02039 3.1e-116 udk 2.7.1.48 F Cytidine monophosphokinase
NPHDNIAI_02040 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NPHDNIAI_02041 1e-66 yneR S Belongs to the HesB IscA family
NPHDNIAI_02042 0.0 S membrane
NPHDNIAI_02043 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
NPHDNIAI_02044 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NPHDNIAI_02045 1.8e-101 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NPHDNIAI_02046 1.6e-74 gluP 3.4.21.105 S Peptidase, S54 family
NPHDNIAI_02047 1.6e-19 gluP 3.4.21.105 S Peptidase, S54 family
NPHDNIAI_02048 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
NPHDNIAI_02049 5.6e-183 glk 2.7.1.2 G Glucokinase
NPHDNIAI_02050 3.4e-67 yqhL P Rhodanese-like protein
NPHDNIAI_02051 5.9e-22 S Protein of unknown function (DUF3042)
NPHDNIAI_02052 7e-175 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NPHDNIAI_02053 6.2e-265 glnA 6.3.1.2 E glutamine synthetase
NPHDNIAI_02054 4.5e-296 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NPHDNIAI_02055 2.3e-173 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
NPHDNIAI_02056 3.9e-12
NPHDNIAI_02057 1.6e-154 P Belongs to the nlpA lipoprotein family
NPHDNIAI_02058 1.4e-98 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NPHDNIAI_02059 4.8e-51 S Iron-sulfur cluster assembly protein
NPHDNIAI_02060 3.2e-80 L transposase and inactivated derivatives, IS30 family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)