ORF_ID e_value Gene_name EC_number CAZy COGs Description
KLHPDMAG_00001 7e-101 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
KLHPDMAG_00003 2.3e-10 soj D CobQ CobB MinD ParA nucleotide binding domain protein
KLHPDMAG_00008 2.5e-39 S Cytochrome B5
KLHPDMAG_00009 1.8e-31
KLHPDMAG_00010 6.1e-109 S CAAX protease self-immunity
KLHPDMAG_00011 1.9e-43
KLHPDMAG_00014 3.5e-61
KLHPDMAG_00017 1.2e-65
KLHPDMAG_00019 8.7e-14 S calcium ion binding
KLHPDMAG_00022 8.6e-08
KLHPDMAG_00024 1.3e-44 K COG3617 Prophage antirepressor
KLHPDMAG_00025 6.1e-14
KLHPDMAG_00026 3.5e-09 xre K sequence-specific DNA binding
KLHPDMAG_00027 3.1e-142 L Belongs to the 'phage' integrase family
KLHPDMAG_00028 5.9e-67
KLHPDMAG_00029 2.6e-55 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KLHPDMAG_00030 2.9e-90 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
KLHPDMAG_00031 6.9e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
KLHPDMAG_00032 1.8e-221 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KLHPDMAG_00033 1.2e-103 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
KLHPDMAG_00034 1.3e-213 folP 2.5.1.15 H dihydropteroate synthase
KLHPDMAG_00035 6.7e-43
KLHPDMAG_00036 4.8e-39
KLHPDMAG_00038 4.2e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KLHPDMAG_00039 2.1e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KLHPDMAG_00040 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
KLHPDMAG_00041 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KLHPDMAG_00042 1.7e-39 yheA S Belongs to the UPF0342 family
KLHPDMAG_00043 8.3e-221 yhaO L Ser Thr phosphatase family protein
KLHPDMAG_00044 0.0 L AAA domain
KLHPDMAG_00045 8.5e-128 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KLHPDMAG_00047 4.1e-77 hit FG histidine triad
KLHPDMAG_00048 1.8e-136 ecsA V ABC transporter, ATP-binding protein
KLHPDMAG_00049 1.9e-217 ecsB U ABC transporter
KLHPDMAG_00050 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KLHPDMAG_00051 8.2e-23 S YSIRK type signal peptide
KLHPDMAG_00052 1.5e-13 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
KLHPDMAG_00053 1.3e-64 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
KLHPDMAG_00054 2.6e-11 glsA 3.5.1.2 E Belongs to the glutaminase family
KLHPDMAG_00055 1.1e-56 ytzB S Small secreted protein
KLHPDMAG_00056 1.8e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KLHPDMAG_00057 1.1e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KLHPDMAG_00058 3.8e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KLHPDMAG_00059 1.4e-119 ybhL S Belongs to the BI1 family
KLHPDMAG_00060 2e-71 yoaK S Protein of unknown function (DUF1275)
KLHPDMAG_00061 1e-15 yoaK S Protein of unknown function (DUF1275)
KLHPDMAG_00062 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KLHPDMAG_00063 1.2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KLHPDMAG_00064 3.2e-96 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KLHPDMAG_00065 1.9e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KLHPDMAG_00066 3e-222 dnaB L replication initiation and membrane attachment
KLHPDMAG_00067 1.9e-172 dnaI L Primosomal protein DnaI
KLHPDMAG_00068 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KLHPDMAG_00069 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KLHPDMAG_00070 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KLHPDMAG_00071 1.4e-95 yqeG S HAD phosphatase, family IIIA
KLHPDMAG_00072 2.1e-218 yqeH S Ribosome biogenesis GTPase YqeH
KLHPDMAG_00073 1.9e-47 yhbY J RNA-binding protein
KLHPDMAG_00074 6.9e-121 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KLHPDMAG_00075 2.8e-111 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
KLHPDMAG_00076 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KLHPDMAG_00077 1.1e-135 yqeM Q Methyltransferase
KLHPDMAG_00078 4.1e-209 ylbM S Belongs to the UPF0348 family
KLHPDMAG_00079 2.9e-99 yceD S Uncharacterized ACR, COG1399
KLHPDMAG_00080 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KLHPDMAG_00081 1.5e-121 K response regulator
KLHPDMAG_00082 3.7e-279 arlS 2.7.13.3 T Histidine kinase
KLHPDMAG_00083 1.3e-266 yjeM E Amino Acid
KLHPDMAG_00084 5.7e-239 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
KLHPDMAG_00085 1.1e-127 IQ Dehydrogenase reductase
KLHPDMAG_00086 3.2e-36
KLHPDMAG_00087 7.7e-112 ywnB S NAD(P)H-binding
KLHPDMAG_00088 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
KLHPDMAG_00089 1.2e-253 nhaC C Na H antiporter NhaC
KLHPDMAG_00090 1.1e-181 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KLHPDMAG_00092 4.1e-98 ydeN S Serine hydrolase
KLHPDMAG_00093 2.9e-27 psiE S Phosphate-starvation-inducible E
KLHPDMAG_00094 8.5e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KLHPDMAG_00096 1.2e-177 S Aldo keto reductase
KLHPDMAG_00097 3.7e-61 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
KLHPDMAG_00098 0.0 L Helicase C-terminal domain protein
KLHPDMAG_00100 2.9e-246 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
KLHPDMAG_00101 3.7e-51 S Sugar efflux transporter for intercellular exchange
KLHPDMAG_00102 2.3e-125
KLHPDMAG_00103 1.3e-123 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
KLHPDMAG_00104 2.5e-311 cadA P P-type ATPase
KLHPDMAG_00105 1.2e-219 5.4.2.7 G Metalloenzyme superfamily
KLHPDMAG_00107 1.6e-35 1.6.5.2 GM NAD(P)H-binding
KLHPDMAG_00108 1.9e-51 1.6.5.2 GM NAD(P)H-binding
KLHPDMAG_00109 3.8e-73 K Transcriptional regulator
KLHPDMAG_00110 1e-162 proX M ABC transporter, substrate-binding protein, QAT family
KLHPDMAG_00111 1.2e-107 proWZ P ABC transporter permease
KLHPDMAG_00112 6.5e-142 proV E ABC transporter, ATP-binding protein
KLHPDMAG_00113 1.9e-102 proW P ABC transporter, permease protein
KLHPDMAG_00114 2e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
KLHPDMAG_00115 2.3e-60 clcA P chloride
KLHPDMAG_00116 1.5e-56 clcA P chloride
KLHPDMAG_00117 5.2e-212 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
KLHPDMAG_00118 3.1e-103 metI P ABC transporter permease
KLHPDMAG_00119 1.4e-190 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KLHPDMAG_00120 2.8e-154 metQ1 P Belongs to the nlpA lipoprotein family
KLHPDMAG_00121 5.3e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KLHPDMAG_00122 3.7e-221 norA EGP Major facilitator Superfamily
KLHPDMAG_00123 8.9e-41 1.3.5.4 S FMN binding
KLHPDMAG_00124 3.2e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KLHPDMAG_00125 3.2e-262 yfnA E amino acid
KLHPDMAG_00126 1.5e-255 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KLHPDMAG_00128 2.4e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KLHPDMAG_00129 0.0 helD 3.6.4.12 L DNA helicase
KLHPDMAG_00130 6.3e-81 ndk 2.7.4.6 F Belongs to the NDK family
KLHPDMAG_00131 2.1e-182 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
KLHPDMAG_00132 7.7e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
KLHPDMAG_00133 2.1e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
KLHPDMAG_00134 1.8e-226 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
KLHPDMAG_00135 1.9e-175
KLHPDMAG_00136 4e-130 cobB K SIR2 family
KLHPDMAG_00138 6.9e-161 yunF F Protein of unknown function DUF72
KLHPDMAG_00139 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KLHPDMAG_00140 6e-154 tatD L hydrolase, TatD family
KLHPDMAG_00141 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KLHPDMAG_00142 2.8e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KLHPDMAG_00143 6.8e-37 veg S Biofilm formation stimulator VEG
KLHPDMAG_00144 1e-81 nrdI F Belongs to the NrdI family
KLHPDMAG_00145 1.3e-235 yhdP S Transporter associated domain
KLHPDMAG_00146 1.1e-153 ypdB V (ABC) transporter
KLHPDMAG_00147 2.8e-88 1.14.14.47, 1.6.5.3, 1.6.99.3 GM epimerase
KLHPDMAG_00148 4.4e-89 M1-874 K Domain of unknown function (DUF1836)
KLHPDMAG_00149 2.3e-78 yybA 2.3.1.57 K Transcriptional regulator
KLHPDMAG_00150 2.8e-131 XK27_07210 6.1.1.6 S B3 4 domain
KLHPDMAG_00151 1.4e-166 S AI-2E family transporter
KLHPDMAG_00152 1.3e-156 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
KLHPDMAG_00153 2.2e-160
KLHPDMAG_00154 1e-133 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
KLHPDMAG_00155 3.6e-138 eutJ E Hsp70 protein
KLHPDMAG_00156 8.3e-159 K helix_turn_helix, arabinose operon control protein
KLHPDMAG_00157 1.6e-37 pduA_4 CQ BMC
KLHPDMAG_00158 2.7e-134 pduB E BMC
KLHPDMAG_00159 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
KLHPDMAG_00160 3.9e-125 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
KLHPDMAG_00161 2.4e-71 pduE 4.2.1.28 Q Dehydratase small subunit
KLHPDMAG_00162 5.6e-309 pduG D Diol dehydratase reactivase ATPase-like domain
KLHPDMAG_00163 2.6e-45 pduH S Dehydratase medium subunit
KLHPDMAG_00164 1.8e-56 pduK CQ BMC
KLHPDMAG_00165 7.8e-40 pduA_4 CQ BMC
KLHPDMAG_00166 1.9e-115 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
KLHPDMAG_00167 1.3e-79 S Putative propanediol utilisation
KLHPDMAG_00168 5.2e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
KLHPDMAG_00169 1e-102 pduO 2.5.1.17 S Cobalamin adenosyltransferase
KLHPDMAG_00170 4.5e-77 pduO S Haem-degrading
KLHPDMAG_00171 3.1e-262 pduP 1.2.1.87 C Aldehyde dehydrogenase family
KLHPDMAG_00172 2.1e-202 pduQ C Iron-containing alcohol dehydrogenase
KLHPDMAG_00173 1.9e-217 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KLHPDMAG_00174 3e-54 pduU E BMC
KLHPDMAG_00175 1.1e-115 3.1.3.48 T Pfam:Y_phosphatase3C
KLHPDMAG_00176 1.9e-75 pgm1 3.1.3.73 G phosphoglycerate mutase
KLHPDMAG_00177 5.9e-68 P Cadmium resistance transporter
KLHPDMAG_00178 2.6e-68 eutP E Ethanolamine utilisation - propanediol utilisation
KLHPDMAG_00179 2.2e-73 fld C Flavodoxin
KLHPDMAG_00180 2.5e-115 XK27_04590 S NADPH-dependent FMN reductase
KLHPDMAG_00181 3.2e-77 cobO 2.5.1.17 S Cobalamin adenosyltransferase
KLHPDMAG_00182 6.1e-170 cobD 4.1.1.81 E Aminotransferase class I and II
KLHPDMAG_00183 7.3e-205 cbiA 6.3.5.11, 6.3.5.9 F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
KLHPDMAG_00184 2.9e-147 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
KLHPDMAG_00185 1.6e-107 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
KLHPDMAG_00186 6.4e-186 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
KLHPDMAG_00187 1.6e-79 cbiE 2.1.1.132, 2.1.1.289 H Tetrapyrrole (Corrin/Porphyrin) Methylases
KLHPDMAG_00188 1.4e-77 cbiT 2.1.1.132, 2.1.1.196 H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
KLHPDMAG_00189 8.1e-129 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
KLHPDMAG_00190 3.3e-144 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
KLHPDMAG_00191 1.1e-127 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H Tetrapyrrole (Corrin/Porphyrin) Methylases
KLHPDMAG_00192 2.5e-98 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H Precorrin-6x reductase CbiJ/CobK
KLHPDMAG_00193 2.7e-178 cobA 2.1.1.107, 4.2.1.75 H Tetrapyrrole (Corrin/Porphyrin) Methylases
KLHPDMAG_00194 1.8e-107 cbiK 4.99.1.3 H Cobalt chelatase (CbiK)
KLHPDMAG_00195 8.1e-91 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Tetrapyrrole (Corrin/Porphyrin) Methylases
KLHPDMAG_00196 1e-123 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
KLHPDMAG_00197 7.6e-44 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
KLHPDMAG_00198 6.8e-103 cbiQ P Cobalt transport protein
KLHPDMAG_00199 7.8e-122 cbiO 2.1.1.195 P part of an ABC transporter complex. Responsible for energy coupling to the transport system
KLHPDMAG_00200 2.7e-240 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
KLHPDMAG_00201 7e-59 cysG 1.3.1.76, 4.99.1.4 H Putative NAD(P)-binding
KLHPDMAG_00202 4.1e-194 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KLHPDMAG_00203 2.6e-137 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
KLHPDMAG_00204 2.8e-174 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
KLHPDMAG_00205 1.1e-239 hemL 5.4.3.8 H Aminotransferase class-III
KLHPDMAG_00206 1.6e-76 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Cobinamide kinase / cobinamide phosphate guanyltransferase
KLHPDMAG_00207 2.2e-118 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
KLHPDMAG_00208 5.8e-74 gpm 3.1.3.73, 5.4.2.12 G Belongs to the phosphoglycerate mutase family
KLHPDMAG_00209 6.5e-64 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
KLHPDMAG_00210 2e-146 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
KLHPDMAG_00211 1.6e-153 ykoT GT2 M Glycosyl transferase family 2
KLHPDMAG_00212 8.4e-65 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KLHPDMAG_00213 1.1e-36
KLHPDMAG_00214 1.7e-114 S Bacterial membrane protein YfhO
KLHPDMAG_00215 7.1e-80 cps3I G Acyltransferase family
KLHPDMAG_00216 1.7e-15
KLHPDMAG_00217 3.1e-75 M Domain of unknown function (DUF4422)
KLHPDMAG_00218 1.5e-43 M biosynthesis protein
KLHPDMAG_00219 3.7e-96 cps3F
KLHPDMAG_00220 7.4e-100 M Glycosyltransferase like family 2
KLHPDMAG_00221 3e-115 S Glycosyltransferase like family 2
KLHPDMAG_00222 2.6e-71 rgpB GT2 M Glycosyl transferase family 2
KLHPDMAG_00223 8.2e-223 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
KLHPDMAG_00224 5.2e-217 glf 5.4.99.9 M UDP-galactopyranose mutase
KLHPDMAG_00225 1.8e-24
KLHPDMAG_00226 0.0 G Peptidase_C39 like family
KLHPDMAG_00227 0.0 2.7.7.6 M Peptidase family M23
KLHPDMAG_00228 2.2e-114 rfbP 2.7.8.6 M Bacterial sugar transferase
KLHPDMAG_00229 3.1e-170 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
KLHPDMAG_00230 1.9e-146 cps1D M Domain of unknown function (DUF4422)
KLHPDMAG_00231 3.2e-136 recX 2.4.1.337 GT4 S Regulatory protein RecX
KLHPDMAG_00232 4.9e-31
KLHPDMAG_00233 2.5e-33 S Protein of unknown function (DUF2922)
KLHPDMAG_00234 1.4e-143 yihY S Belongs to the UPF0761 family
KLHPDMAG_00235 9e-281 yjeM E Amino Acid
KLHPDMAG_00236 1.3e-252 E Arginine ornithine antiporter
KLHPDMAG_00237 2.1e-221 arcT 2.6.1.1 E Aminotransferase
KLHPDMAG_00238 1.3e-167 map 3.4.11.18 E Methionine Aminopeptidase
KLHPDMAG_00239 6.1e-79 fld C Flavodoxin
KLHPDMAG_00240 1.3e-67 gtcA S Teichoic acid glycosylation protein
KLHPDMAG_00241 5.8e-16
KLHPDMAG_00242 3.6e-31
KLHPDMAG_00243 9e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KLHPDMAG_00245 1.9e-231 yfmL L DEAD DEAH box helicase
KLHPDMAG_00246 1.4e-189 mocA S Oxidoreductase
KLHPDMAG_00247 9.1e-62 S Domain of unknown function (DUF4828)
KLHPDMAG_00248 3.6e-105 yvdD 3.2.2.10 S Belongs to the LOG family
KLHPDMAG_00249 4.5e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KLHPDMAG_00250 1.1e-297 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
KLHPDMAG_00251 6.7e-195 S Protein of unknown function (DUF3114)
KLHPDMAG_00252 1.3e-78 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
KLHPDMAG_00253 1e-117 ybhL S Belongs to the BI1 family
KLHPDMAG_00254 7.1e-69 yhjX P Major Facilitator Superfamily
KLHPDMAG_00256 7e-92 K Acetyltransferase (GNAT) family
KLHPDMAG_00257 6e-76 K LytTr DNA-binding domain
KLHPDMAG_00258 6.8e-67 S Protein of unknown function (DUF3021)
KLHPDMAG_00259 1.2e-155 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
KLHPDMAG_00260 3.1e-75 ogt 2.1.1.63 L Methyltransferase
KLHPDMAG_00261 7.5e-123 pnb C nitroreductase
KLHPDMAG_00262 1.7e-91
KLHPDMAG_00263 4.3e-83 yvbK 3.1.3.25 K GNAT family
KLHPDMAG_00264 3.4e-247 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
KLHPDMAG_00265 9.2e-204 amtB P ammonium transporter
KLHPDMAG_00266 5.7e-29
KLHPDMAG_00267 3.8e-130 mltD CBM50 M NlpC P60 family protein
KLHPDMAG_00269 2.2e-57
KLHPDMAG_00270 6e-208 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KLHPDMAG_00271 1.1e-218 EG GntP family permease
KLHPDMAG_00272 2.2e-31 KT Putative sugar diacid recognition
KLHPDMAG_00273 4e-32 KT Putative sugar diacid recognition
KLHPDMAG_00274 6.7e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KLHPDMAG_00275 2.9e-218 patA 2.6.1.1 E Aminotransferase
KLHPDMAG_00276 4.3e-141 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KLHPDMAG_00277 1e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KLHPDMAG_00278 1.1e-222 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KLHPDMAG_00279 7e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KLHPDMAG_00280 2e-244 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KLHPDMAG_00281 2.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
KLHPDMAG_00282 3.2e-181 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KLHPDMAG_00283 6.9e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KLHPDMAG_00284 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KLHPDMAG_00285 9.9e-118 S Repeat protein
KLHPDMAG_00286 6.4e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
KLHPDMAG_00287 1.8e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KLHPDMAG_00288 7.5e-58 XK27_04120 S Putative amino acid metabolism
KLHPDMAG_00289 8.3e-218 iscS 2.8.1.7 E Aminotransferase class V
KLHPDMAG_00290 1.1e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KLHPDMAG_00292 7e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
KLHPDMAG_00293 4.2e-32 cspA K Cold shock protein
KLHPDMAG_00294 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KLHPDMAG_00295 1.3e-35 divIVA D DivIVA domain protein
KLHPDMAG_00296 2.4e-144 ylmH S S4 domain protein
KLHPDMAG_00297 3.2e-40 yggT S YGGT family
KLHPDMAG_00298 2.1e-70 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KLHPDMAG_00299 1e-221 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KLHPDMAG_00300 2.5e-253 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KLHPDMAG_00301 2.1e-141 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KLHPDMAG_00302 9.5e-203 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KLHPDMAG_00303 6.1e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KLHPDMAG_00304 2.2e-179 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KLHPDMAG_00305 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
KLHPDMAG_00306 3.8e-55 ftsL D Cell division protein FtsL
KLHPDMAG_00307 1.5e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KLHPDMAG_00308 3.1e-77 mraZ K Belongs to the MraZ family
KLHPDMAG_00309 1.7e-57
KLHPDMAG_00310 1.2e-10 S Protein of unknown function (DUF4044)
KLHPDMAG_00311 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KLHPDMAG_00312 2.3e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KLHPDMAG_00313 1e-159 rrmA 2.1.1.187 H Methyltransferase
KLHPDMAG_00314 6.6e-182 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
KLHPDMAG_00316 1.1e-95 L Transposase IS66 family
KLHPDMAG_00317 2.2e-105 L Transposase IS66 family
KLHPDMAG_00318 2.3e-53 trxA O Belongs to the thioredoxin family
KLHPDMAG_00319 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KLHPDMAG_00320 1.6e-86 cvpA S Colicin V production protein
KLHPDMAG_00321 6.1e-48 yrzB S Belongs to the UPF0473 family
KLHPDMAG_00322 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KLHPDMAG_00323 4.1e-43 yrzL S Belongs to the UPF0297 family
KLHPDMAG_00324 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KLHPDMAG_00325 3.7e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KLHPDMAG_00326 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
KLHPDMAG_00327 6.2e-31 yajC U Preprotein translocase
KLHPDMAG_00328 1.1e-187 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KLHPDMAG_00329 4.2e-189 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KLHPDMAG_00330 4.3e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KLHPDMAG_00331 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KLHPDMAG_00332 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KLHPDMAG_00333 2.1e-208 rny S Endoribonuclease that initiates mRNA decay
KLHPDMAG_00334 1.7e-196 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KLHPDMAG_00335 8.1e-227 cinA 3.5.1.42 S Belongs to the CinA family
KLHPDMAG_00336 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KLHPDMAG_00337 5e-137 ymfM S Helix-turn-helix domain
KLHPDMAG_00338 6.7e-248 ymfH S Peptidase M16
KLHPDMAG_00339 5.3e-226 ymfF S Peptidase M16 inactive domain protein
KLHPDMAG_00340 1.7e-159 aatB ET ABC transporter substrate-binding protein
KLHPDMAG_00341 1.2e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KLHPDMAG_00342 3.2e-102 glnP P ABC transporter permease
KLHPDMAG_00343 8.7e-93 mreD M rod shape-determining protein MreD
KLHPDMAG_00344 3.5e-152 mreC M Involved in formation and maintenance of cell shape
KLHPDMAG_00345 1.7e-179 mreB D cell shape determining protein MreB
KLHPDMAG_00346 8e-122 radC L DNA repair protein
KLHPDMAG_00347 2.5e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KLHPDMAG_00348 1.8e-231 ndh 1.6.99.3 C NADH dehydrogenase
KLHPDMAG_00349 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KLHPDMAG_00350 2.8e-310 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
KLHPDMAG_00351 4.5e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
KLHPDMAG_00352 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
KLHPDMAG_00353 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KLHPDMAG_00354 9.4e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KLHPDMAG_00355 3.3e-214 iscS2 2.8.1.7 E Aminotransferase class V
KLHPDMAG_00356 5.9e-244 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KLHPDMAG_00357 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KLHPDMAG_00358 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KLHPDMAG_00359 2.9e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KLHPDMAG_00360 2.4e-220 patA 2.6.1.1 E Aminotransferase
KLHPDMAG_00361 1.4e-122 trmK 2.1.1.217 S SAM-dependent methyltransferase
KLHPDMAG_00362 1.1e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KLHPDMAG_00363 4.3e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KLHPDMAG_00364 2.8e-93 L Belongs to the 'phage' integrase family
KLHPDMAG_00365 1.6e-23
KLHPDMAG_00368 4.9e-24
KLHPDMAG_00370 1.8e-79 3.4.21.88 K Peptidase S24-like
KLHPDMAG_00371 2.8e-10 K Helix-turn-helix XRE-family like proteins
KLHPDMAG_00381 7.4e-113 L DnaD domain protein
KLHPDMAG_00382 1.2e-85 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
KLHPDMAG_00383 7.2e-138 L Belongs to the 'phage' integrase family
KLHPDMAG_00385 2.2e-09
KLHPDMAG_00386 2.9e-41 S HNH endonuclease
KLHPDMAG_00388 1.5e-68
KLHPDMAG_00389 8.3e-126
KLHPDMAG_00396 6.1e-82 arpU S Phage transcriptional regulator, ArpU family
KLHPDMAG_00397 5.6e-17
KLHPDMAG_00399 4.9e-08
KLHPDMAG_00401 1.6e-08
KLHPDMAG_00402 8.1e-88 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
KLHPDMAG_00403 1.4e-170 bcgIA 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
KLHPDMAG_00404 4.5e-59 L HNH nucleases
KLHPDMAG_00405 2.5e-64 L Phage terminase, small subunit
KLHPDMAG_00406 7.5e-285 S overlaps another CDS with the same product name
KLHPDMAG_00407 4.1e-204 S Phage portal protein
KLHPDMAG_00408 2e-108 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
KLHPDMAG_00409 7.6e-142 S Phage capsid family
KLHPDMAG_00410 1.5e-35 S Phage gp6-like head-tail connector protein
KLHPDMAG_00411 2.2e-39 S Phage head-tail joining protein
KLHPDMAG_00412 1.3e-38 S Bacteriophage HK97-gp10, putative tail-component
KLHPDMAG_00413 1.1e-36 S Protein of unknown function (DUF806)
KLHPDMAG_00414 2.9e-112 S Phage tail tube protein
KLHPDMAG_00415 1.2e-11 S Phage tail assembly chaperone proteins, TAC
KLHPDMAG_00416 2.1e-199 M Phage tail tape measure protein TP901
KLHPDMAG_00417 1.3e-156 S Phage tail protein
KLHPDMAG_00418 7.4e-277 M Prophage endopeptidase tail
KLHPDMAG_00419 5.6e-36
KLHPDMAG_00421 1e-95 S Domain of unknown function (DUF2479)
KLHPDMAG_00423 5.8e-36 S Bacteriophage holin family
KLHPDMAG_00424 1.4e-43 S Bacteriophage holin of superfamily 6 (Holin_LLH)
KLHPDMAG_00425 1e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KLHPDMAG_00426 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KLHPDMAG_00427 2.2e-163 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KLHPDMAG_00428 1.5e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KLHPDMAG_00429 1.9e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KLHPDMAG_00430 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KLHPDMAG_00431 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KLHPDMAG_00432 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
KLHPDMAG_00433 5.9e-233 pyrP F Permease
KLHPDMAG_00434 2.6e-130 yibF S overlaps another CDS with the same product name
KLHPDMAG_00435 5.8e-192 yibE S overlaps another CDS with the same product name
KLHPDMAG_00436 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KLHPDMAG_00437 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KLHPDMAG_00438 3.3e-228 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KLHPDMAG_00439 4e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KLHPDMAG_00440 9.5e-166 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KLHPDMAG_00441 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KLHPDMAG_00442 6e-108 tdk 2.7.1.21 F thymidine kinase
KLHPDMAG_00443 7.5e-263 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
KLHPDMAG_00444 3.2e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
KLHPDMAG_00445 2.3e-222 arcD U Amino acid permease
KLHPDMAG_00446 3.2e-259 E Arginine ornithine antiporter
KLHPDMAG_00447 2.7e-79 argR K Regulates arginine biosynthesis genes
KLHPDMAG_00448 3.1e-218 arcA 3.5.3.6 E Arginine
KLHPDMAG_00449 5.3e-184 ampC V Beta-lactamase
KLHPDMAG_00450 7e-19
KLHPDMAG_00451 1.8e-59 M domain protein
KLHPDMAG_00452 1.4e-120 M domain protein
KLHPDMAG_00453 1.4e-168 M domain protein
KLHPDMAG_00454 9.5e-133 M domain protein
KLHPDMAG_00455 1.8e-92
KLHPDMAG_00457 3e-45 yjcE P Sodium proton antiporter
KLHPDMAG_00458 3.1e-147 yjcE P Sodium proton antiporter
KLHPDMAG_00459 1.8e-56
KLHPDMAG_00461 3.1e-86
KLHPDMAG_00462 0.0 copA 3.6.3.54 P P-type ATPase
KLHPDMAG_00463 9.2e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
KLHPDMAG_00464 1.1e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
KLHPDMAG_00465 5.9e-103 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
KLHPDMAG_00466 3.9e-162 EG EamA-like transporter family
KLHPDMAG_00467 3.6e-171 arcC 2.7.2.2 E Belongs to the carbamate kinase family
KLHPDMAG_00468 7.6e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KLHPDMAG_00469 3.6e-154 KT YcbB domain
KLHPDMAG_00470 3.1e-30 xylB 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
KLHPDMAG_00472 1.3e-94 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
KLHPDMAG_00473 3.7e-56 ltrA S Bacterial low temperature requirement A protein (LtrA)
KLHPDMAG_00474 3.4e-43 ltrA S Bacterial low temperature requirement A protein (LtrA)
KLHPDMAG_00475 1.6e-79 uspA T universal stress protein
KLHPDMAG_00476 4e-78 K AsnC family
KLHPDMAG_00477 4.5e-228 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KLHPDMAG_00478 2.4e-99 dedA 3.1.3.1 S SNARE associated Golgi protein
KLHPDMAG_00479 2e-180 galR K Transcriptional regulator
KLHPDMAG_00480 1.1e-278 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KLHPDMAG_00481 2.5e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KLHPDMAG_00482 2.5e-175 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
KLHPDMAG_00483 1.2e-143 ptp3 3.1.3.48 T Tyrosine phosphatase family
KLHPDMAG_00484 3.1e-92 yxkA S Phosphatidylethanolamine-binding protein
KLHPDMAG_00485 9.1e-36
KLHPDMAG_00486 2e-52
KLHPDMAG_00487 1.1e-201
KLHPDMAG_00488 7.5e-83 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KLHPDMAG_00489 1.3e-134 pnuC H nicotinamide mononucleotide transporter
KLHPDMAG_00490 3.9e-156 ytbE 1.1.1.346 S Aldo keto reductase
KLHPDMAG_00491 3.7e-125 K response regulator
KLHPDMAG_00492 6.9e-181 T PhoQ Sensor
KLHPDMAG_00493 8.3e-134 macB2 V ABC transporter, ATP-binding protein
KLHPDMAG_00494 0.0 ysaB V FtsX-like permease family
KLHPDMAG_00495 1.9e-155 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
KLHPDMAG_00496 1.4e-167 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KLHPDMAG_00497 6.2e-10 K helix_turn_helix, mercury resistance
KLHPDMAG_00498 7.1e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KLHPDMAG_00499 6.2e-197 EGP Major facilitator Superfamily
KLHPDMAG_00500 6e-88 ymdB S Macro domain protein
KLHPDMAG_00501 2.9e-35 K Helix-turn-helix XRE-family like proteins
KLHPDMAG_00502 0.0 pepO 3.4.24.71 O Peptidase family M13
KLHPDMAG_00503 5.1e-47
KLHPDMAG_00504 1.9e-231 S Putative metallopeptidase domain
KLHPDMAG_00505 4.4e-203 3.1.3.1 S associated with various cellular activities
KLHPDMAG_00506 5.2e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
KLHPDMAG_00507 5.9e-64 yeaO S Protein of unknown function, DUF488
KLHPDMAG_00509 4.4e-118 yrkL S Flavodoxin-like fold
KLHPDMAG_00510 1.5e-52
KLHPDMAG_00511 5.3e-16 S Domain of unknown function (DUF4767)
KLHPDMAG_00512 2.2e-20 3.6.4.12 S PD-(D/E)XK nuclease family transposase
KLHPDMAG_00513 3.4e-48
KLHPDMAG_00514 2.6e-205 nrnB S DHHA1 domain
KLHPDMAG_00515 1.8e-226 S Uncharacterized protein conserved in bacteria (DUF2325)
KLHPDMAG_00516 2.4e-248 brnQ U Component of the transport system for branched-chain amino acids
KLHPDMAG_00517 1.7e-105 NU mannosyl-glycoprotein
KLHPDMAG_00518 2.3e-140 S Putative ABC-transporter type IV
KLHPDMAG_00519 1.9e-179 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KLHPDMAG_00520 1.7e-17 K Winged helix DNA-binding domain
KLHPDMAG_00521 9.8e-287 lmrA V ABC transporter, ATP-binding protein
KLHPDMAG_00522 0.0 yfiC V ABC transporter
KLHPDMAG_00523 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
KLHPDMAG_00524 5.8e-269 pipD E Dipeptidase
KLHPDMAG_00525 1.6e-85 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KLHPDMAG_00526 4.7e-126 gntR K UbiC transcription regulator-associated domain protein
KLHPDMAG_00527 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
KLHPDMAG_00528 3.6e-236 yagE E amino acid
KLHPDMAG_00529 7.3e-118 aroD S Serine hydrolase (FSH1)
KLHPDMAG_00530 2.2e-238 brnQ U Component of the transport system for branched-chain amino acids
KLHPDMAG_00531 2.9e-165 GK ROK family
KLHPDMAG_00532 0.0 tetP J elongation factor G
KLHPDMAG_00533 6.6e-81 uspA T universal stress protein
KLHPDMAG_00534 3.3e-194 lplA 6.3.1.20 H Lipoate-protein ligase
KLHPDMAG_00535 7.1e-63
KLHPDMAG_00536 4e-14
KLHPDMAG_00537 7e-57
KLHPDMAG_00538 1.8e-38
KLHPDMAG_00539 6.7e-135 V ABC transporter
KLHPDMAG_00540 1.4e-209 EGP Major facilitator Superfamily
KLHPDMAG_00541 5.5e-256 G PTS system Galactitol-specific IIC component
KLHPDMAG_00542 8.5e-33 1.6.5.5 C Zinc-binding dehydrogenase
KLHPDMAG_00543 2.8e-86 1.6.5.5 C Zinc-binding dehydrogenase
KLHPDMAG_00544 2e-19 1.6.5.5 C Zinc-binding dehydrogenase
KLHPDMAG_00545 1.7e-159
KLHPDMAG_00546 6.5e-72 K Transcriptional regulator
KLHPDMAG_00547 2e-172 D Alpha beta
KLHPDMAG_00548 1.4e-51 ypaA S Protein of unknown function (DUF1304)
KLHPDMAG_00549 0.0 yjcE P Sodium proton antiporter
KLHPDMAG_00550 1.6e-52 yvlA
KLHPDMAG_00551 2.7e-112 P Cobalt transport protein
KLHPDMAG_00552 1.3e-246 cbiO1 S ABC transporter, ATP-binding protein
KLHPDMAG_00553 1.3e-96 S ABC-type cobalt transport system, permease component
KLHPDMAG_00554 3.3e-133 S membrane transporter protein
KLHPDMAG_00555 4e-113 IQ KR domain
KLHPDMAG_00556 2e-09 IQ KR domain
KLHPDMAG_00557 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KLHPDMAG_00558 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KLHPDMAG_00559 5.8e-146 recO L Involved in DNA repair and RecF pathway recombination
KLHPDMAG_00560 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KLHPDMAG_00561 2.1e-59 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KLHPDMAG_00562 1.2e-82 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KLHPDMAG_00563 1.1e-181 phoH T phosphate starvation-inducible protein PhoH
KLHPDMAG_00564 7.6e-172 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KLHPDMAG_00565 1.3e-83 bioY S BioY family
KLHPDMAG_00566 7.1e-264 argH 4.3.2.1 E argininosuccinate lyase
KLHPDMAG_00567 1.7e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KLHPDMAG_00568 3.5e-185 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KLHPDMAG_00569 3.8e-70 yqeY S YqeY-like protein
KLHPDMAG_00570 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KLHPDMAG_00571 5.5e-262 glnPH2 P ABC transporter permease
KLHPDMAG_00572 1e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KLHPDMAG_00573 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KLHPDMAG_00574 9.3e-166 yniA G Phosphotransferase enzyme family
KLHPDMAG_00575 8.4e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KLHPDMAG_00576 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KLHPDMAG_00577 8.5e-51
KLHPDMAG_00578 6.7e-128 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KLHPDMAG_00579 1.3e-179 prmA J Ribosomal protein L11 methyltransferase
KLHPDMAG_00580 7.5e-58
KLHPDMAG_00581 1.2e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KLHPDMAG_00583 4e-198 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
KLHPDMAG_00584 2e-274 pipD E Dipeptidase
KLHPDMAG_00585 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KLHPDMAG_00586 9.5e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KLHPDMAG_00587 0.0 dnaK O Heat shock 70 kDa protein
KLHPDMAG_00588 1e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KLHPDMAG_00589 1e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KLHPDMAG_00590 6.5e-63
KLHPDMAG_00591 4.5e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KLHPDMAG_00592 2.1e-163 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KLHPDMAG_00593 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KLHPDMAG_00594 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KLHPDMAG_00595 1.3e-48 ylxQ J ribosomal protein
KLHPDMAG_00596 1e-44 ylxR K Protein of unknown function (DUF448)
KLHPDMAG_00597 2.3e-215 nusA K Participates in both transcription termination and antitermination
KLHPDMAG_00598 9.4e-83 rimP J Required for maturation of 30S ribosomal subunits
KLHPDMAG_00599 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KLHPDMAG_00600 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KLHPDMAG_00601 3.7e-235 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
KLHPDMAG_00602 5.8e-138 cdsA 2.7.7.41 I Belongs to the CDS family
KLHPDMAG_00603 2.4e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KLHPDMAG_00604 1.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KLHPDMAG_00605 8.2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KLHPDMAG_00606 9.3e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KLHPDMAG_00607 4.6e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
KLHPDMAG_00608 7e-181 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KLHPDMAG_00609 7.1e-49 yazA L GIY-YIG catalytic domain protein
KLHPDMAG_00610 2.7e-140 yabB 2.1.1.223 L Methyltransferase small domain
KLHPDMAG_00611 4.6e-117 plsC 2.3.1.51 I Acyltransferase
KLHPDMAG_00612 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
KLHPDMAG_00613 1.3e-35 ynzC S UPF0291 protein
KLHPDMAG_00614 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KLHPDMAG_00615 2.4e-209 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
KLHPDMAG_00616 4.3e-126 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KLHPDMAG_00618 5e-52
KLHPDMAG_00619 2.1e-67
KLHPDMAG_00621 2.1e-07 L DnaD domain protein
KLHPDMAG_00625 2.3e-08
KLHPDMAG_00628 1.7e-44 K COG3617 Prophage antirepressor
KLHPDMAG_00629 6.7e-27
KLHPDMAG_00631 5.7e-16 K Transcriptional
KLHPDMAG_00632 4.6e-133 L Belongs to the 'phage' integrase family
KLHPDMAG_00633 7.3e-88
KLHPDMAG_00634 9.2e-92 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KLHPDMAG_00635 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
KLHPDMAG_00636 2.1e-154 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KLHPDMAG_00637 4.9e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KLHPDMAG_00638 1.2e-247 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KLHPDMAG_00639 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KLHPDMAG_00640 7.6e-09
KLHPDMAG_00641 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
KLHPDMAG_00642 4e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
KLHPDMAG_00643 6.9e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KLHPDMAG_00644 1.4e-237 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KLHPDMAG_00645 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KLHPDMAG_00646 7.1e-164 S Tetratricopeptide repeat
KLHPDMAG_00647 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KLHPDMAG_00648 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KLHPDMAG_00649 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
KLHPDMAG_00650 3.1e-147 holA 2.7.7.7 L DNA polymerase III delta subunit
KLHPDMAG_00651 0.0 comEC S Competence protein ComEC
KLHPDMAG_00652 3.1e-89 comEB 3.5.4.12 F ComE operon protein 2
KLHPDMAG_00653 5.8e-80 comEA L Competence protein ComEA
KLHPDMAG_00654 1.9e-197 ylbL T Belongs to the peptidase S16 family
KLHPDMAG_00655 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KLHPDMAG_00656 1.6e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
KLHPDMAG_00657 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
KLHPDMAG_00658 2.7e-222 ftsW D Belongs to the SEDS family
KLHPDMAG_00659 0.0 typA T GTP-binding protein TypA
KLHPDMAG_00660 3.8e-134 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
KLHPDMAG_00661 3.7e-45 yktA S Belongs to the UPF0223 family
KLHPDMAG_00662 1.4e-275 lpdA 1.8.1.4 C Dehydrogenase
KLHPDMAG_00663 1.7e-222 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KLHPDMAG_00664 2.4e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
KLHPDMAG_00665 2.8e-207 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
KLHPDMAG_00666 1.4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KLHPDMAG_00667 4.8e-79
KLHPDMAG_00668 9.8e-32 ykzG S Belongs to the UPF0356 family
KLHPDMAG_00669 8.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
KLHPDMAG_00670 5.5e-161 degV S EDD domain protein, DegV family
KLHPDMAG_00671 3e-90
KLHPDMAG_00672 1.1e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
KLHPDMAG_00673 3.7e-154 gspA M family 8
KLHPDMAG_00674 2.8e-154 S Alpha beta hydrolase
KLHPDMAG_00675 1.5e-94 K Acetyltransferase (GNAT) domain
KLHPDMAG_00676 2.4e-240 XK27_08635 S UPF0210 protein
KLHPDMAG_00677 2.1e-39 gcvR T Belongs to the UPF0237 family
KLHPDMAG_00678 7.2e-169 1.1.1.346 C Aldo keto reductase
KLHPDMAG_00679 1.1e-158 K LysR substrate binding domain protein
KLHPDMAG_00680 1.5e-80 C Flavodoxin
KLHPDMAG_00681 1.2e-77 yphH S Cupin domain
KLHPDMAG_00682 1.7e-73 yeaL S UPF0756 membrane protein
KLHPDMAG_00683 4e-243 EGP Major facilitator Superfamily
KLHPDMAG_00684 5e-75 copY K Copper transport repressor CopY TcrY
KLHPDMAG_00685 8.5e-246 yhdP S Transporter associated domain
KLHPDMAG_00686 0.0 ubiB S ABC1 family
KLHPDMAG_00687 4.3e-144 S DUF218 domain
KLHPDMAG_00688 2.1e-67 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KLHPDMAG_00689 1.6e-56 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KLHPDMAG_00690 4.5e-55 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KLHPDMAG_00691 0.0 uvrA3 L excinuclease ABC, A subunit
KLHPDMAG_00692 3.7e-120 S SNARE associated Golgi protein
KLHPDMAG_00693 2.3e-229 N Uncharacterized conserved protein (DUF2075)
KLHPDMAG_00694 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KLHPDMAG_00696 6.6e-254 yifK E Amino acid permease
KLHPDMAG_00697 7.2e-158 endA V DNA/RNA non-specific endonuclease
KLHPDMAG_00698 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KLHPDMAG_00699 2.3e-41 ybaN S Protein of unknown function (DUF454)
KLHPDMAG_00700 7e-72 S Protein of unknown function (DUF3290)
KLHPDMAG_00701 6.2e-114 yviA S Protein of unknown function (DUF421)
KLHPDMAG_00702 1.2e-163 S Alpha/beta hydrolase of unknown function (DUF915)
KLHPDMAG_00703 2e-18
KLHPDMAG_00704 2.1e-90 ntd 2.4.2.6 F Nucleoside
KLHPDMAG_00705 3.3e-152 3.1.3.102, 3.1.3.104 S hydrolase
KLHPDMAG_00706 8.9e-41 yrvD S Pfam:DUF1049
KLHPDMAG_00708 8.9e-10 S Phage derived protein Gp49-like (DUF891)
KLHPDMAG_00709 8e-12 S Phage derived protein Gp49-like (DUF891)
KLHPDMAG_00710 5e-20 K Helix-turn-helix XRE-family like proteins
KLHPDMAG_00711 3.3e-163 I alpha/beta hydrolase fold
KLHPDMAG_00712 1.8e-113 frnE Q DSBA-like thioredoxin domain
KLHPDMAG_00717 5.5e-198 gntT EG Gluconate
KLHPDMAG_00718 4.9e-182 K Transcriptional regulator, LacI family
KLHPDMAG_00719 3.5e-288 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
KLHPDMAG_00720 2.6e-92
KLHPDMAG_00721 6.1e-25
KLHPDMAG_00722 2e-59 asp S Asp23 family, cell envelope-related function
KLHPDMAG_00723 2.1e-85 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
KLHPDMAG_00725 1e-48
KLHPDMAG_00726 2.7e-67 yqkB S Belongs to the HesB IscA family
KLHPDMAG_00727 3.9e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
KLHPDMAG_00728 1.1e-78 F NUDIX domain
KLHPDMAG_00729 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KLHPDMAG_00730 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KLHPDMAG_00731 1.2e-104 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KLHPDMAG_00732 1.1e-164 lacX 5.1.3.3 G Aldose 1-epimerase
KLHPDMAG_00733 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KLHPDMAG_00734 2.1e-160 dprA LU DNA protecting protein DprA
KLHPDMAG_00735 1.2e-140 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KLHPDMAG_00736 3e-159 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KLHPDMAG_00737 4.4e-35 yozE S Belongs to the UPF0346 family
KLHPDMAG_00738 1.4e-107 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
KLHPDMAG_00739 1.8e-167 ypmR E lipolytic protein G-D-S-L family
KLHPDMAG_00740 2.2e-151 DegV S EDD domain protein, DegV family
KLHPDMAG_00741 1.3e-111 hlyIII S protein, hemolysin III
KLHPDMAG_00742 9.6e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KLHPDMAG_00743 2.7e-190 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KLHPDMAG_00744 0.0 yfmR S ABC transporter, ATP-binding protein
KLHPDMAG_00745 4.5e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KLHPDMAG_00746 2.6e-233 S Tetratricopeptide repeat protein
KLHPDMAG_00747 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KLHPDMAG_00748 9.4e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KLHPDMAG_00749 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
KLHPDMAG_00750 1.7e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KLHPDMAG_00751 2.5e-13 M Lysin motif
KLHPDMAG_00752 3.5e-266 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
KLHPDMAG_00753 2.6e-194 ypbB 5.1.3.1 S Helix-turn-helix domain
KLHPDMAG_00754 7.1e-101 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KLHPDMAG_00756 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KLHPDMAG_00758 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KLHPDMAG_00759 1.2e-227 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KLHPDMAG_00760 5.3e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KLHPDMAG_00761 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KLHPDMAG_00762 1.2e-244 yifK E Amino acid permease
KLHPDMAG_00763 4e-292 clcA P chloride
KLHPDMAG_00764 1.8e-34 secG U Preprotein translocase
KLHPDMAG_00765 3.8e-142 est 3.1.1.1 S Serine aminopeptidase, S33
KLHPDMAG_00766 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KLHPDMAG_00767 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KLHPDMAG_00768 1e-102 yxjI
KLHPDMAG_00769 9e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KLHPDMAG_00770 6.4e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
KLHPDMAG_00771 5.9e-82 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
KLHPDMAG_00772 1e-87 K Acetyltransferase (GNAT) domain
KLHPDMAG_00773 1.3e-75 S PAS domain
KLHPDMAG_00774 3.9e-101 dnaQ 2.7.7.7 L DNA polymerase III
KLHPDMAG_00775 1.5e-166 murB 1.3.1.98 M Cell wall formation
KLHPDMAG_00776 3.9e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KLHPDMAG_00777 5.1e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KLHPDMAG_00778 3.7e-249 fucP G Major Facilitator Superfamily
KLHPDMAG_00779 9.4e-150 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KLHPDMAG_00780 5.8e-126 ybbR S YbbR-like protein
KLHPDMAG_00781 8.5e-254 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KLHPDMAG_00782 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KLHPDMAG_00783 5.6e-52
KLHPDMAG_00784 0.0 oatA I Acyltransferase
KLHPDMAG_00785 1.8e-78 K Transcriptional regulator
KLHPDMAG_00786 1.1e-147 XK27_02985 S Cof-like hydrolase
KLHPDMAG_00787 5e-73 lytE M Lysin motif
KLHPDMAG_00789 1.6e-134 K response regulator
KLHPDMAG_00790 7.6e-272 yclK 2.7.13.3 T Histidine kinase
KLHPDMAG_00791 4.1e-153 glcU U sugar transport
KLHPDMAG_00792 9.6e-96 lacA 2.3.1.79 S Transferase hexapeptide repeat
KLHPDMAG_00793 8.5e-262 pgi 5.3.1.9 G Belongs to the GPI family
KLHPDMAG_00794 1e-25
KLHPDMAG_00795 3e-142 S Hydrolases of the alpha beta superfamily
KLHPDMAG_00796 2.1e-196 adhP 1.1.1.1 C alcohol dehydrogenase
KLHPDMAG_00797 4.4e-77 ctsR K Belongs to the CtsR family
KLHPDMAG_00798 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KLHPDMAG_00799 3e-110 K Bacterial regulatory proteins, tetR family
KLHPDMAG_00800 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KLHPDMAG_00801 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KLHPDMAG_00802 2.3e-199 ykiI
KLHPDMAG_00803 1.7e-106 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
KLHPDMAG_00804 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KLHPDMAG_00805 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KLHPDMAG_00806 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KLHPDMAG_00807 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
KLHPDMAG_00808 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KLHPDMAG_00809 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
KLHPDMAG_00810 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KLHPDMAG_00811 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KLHPDMAG_00812 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KLHPDMAG_00813 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KLHPDMAG_00814 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KLHPDMAG_00815 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KLHPDMAG_00816 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
KLHPDMAG_00817 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KLHPDMAG_00818 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KLHPDMAG_00819 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KLHPDMAG_00820 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KLHPDMAG_00821 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KLHPDMAG_00822 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KLHPDMAG_00823 2.1e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KLHPDMAG_00824 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KLHPDMAG_00825 6.3e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KLHPDMAG_00826 2.9e-24 rpmD J Ribosomal protein L30
KLHPDMAG_00827 1.5e-63 rplO J Binds to the 23S rRNA
KLHPDMAG_00828 2.6e-239 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KLHPDMAG_00829 1.5e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KLHPDMAG_00830 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KLHPDMAG_00831 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KLHPDMAG_00832 6.2e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KLHPDMAG_00833 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KLHPDMAG_00834 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KLHPDMAG_00835 1.5e-62 rplQ J Ribosomal protein L17
KLHPDMAG_00836 1.5e-139 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KLHPDMAG_00837 9.5e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KLHPDMAG_00838 9.8e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KLHPDMAG_00839 3e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KLHPDMAG_00840 1.4e-110 lssY 3.6.1.27 I Acid phosphatase homologues
KLHPDMAG_00841 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
KLHPDMAG_00842 9.2e-68 L PFAM transposase IS116 IS110 IS902
KLHPDMAG_00843 1.5e-41 L PFAM transposase IS116 IS110 IS902
KLHPDMAG_00844 1.3e-227 clcA_2 P Chloride transporter, ClC family
KLHPDMAG_00845 1.5e-115 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
KLHPDMAG_00846 1.6e-146 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KLHPDMAG_00847 1.7e-137 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KLHPDMAG_00848 2.1e-73
KLHPDMAG_00849 6.8e-173
KLHPDMAG_00850 5.3e-176 fecB P Periplasmic binding protein
KLHPDMAG_00851 7.8e-135 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
KLHPDMAG_00852 1.2e-129 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KLHPDMAG_00853 2.5e-77 S Flavodoxin
KLHPDMAG_00854 3.5e-62 moaE 2.8.1.12 H MoaE protein
KLHPDMAG_00855 3.9e-32 moaD 2.8.1.12 H ThiS family
KLHPDMAG_00856 1.5e-217 narK P Transporter, major facilitator family protein
KLHPDMAG_00857 5.7e-145 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
KLHPDMAG_00858 4.4e-172
KLHPDMAG_00859 9.4e-19
KLHPDMAG_00860 2.3e-116 nreC K PFAM regulatory protein LuxR
KLHPDMAG_00861 1.5e-189 comP 2.7.13.3 F Sensor histidine kinase
KLHPDMAG_00862 2.6e-43
KLHPDMAG_00863 1.2e-95 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
KLHPDMAG_00864 2e-75 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
KLHPDMAG_00865 8.2e-224 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
KLHPDMAG_00866 5.8e-83 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
KLHPDMAG_00867 1.8e-184 moeB 2.7.7.73, 2.7.7.80 H ThiF family
KLHPDMAG_00868 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KLHPDMAG_00869 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
KLHPDMAG_00870 1.5e-98 narJ C nitrate reductase molybdenum cofactor assembly chaperone
KLHPDMAG_00871 9.6e-129 narI 1.7.5.1 C Nitrate reductase
KLHPDMAG_00872 4.2e-153 EG EamA-like transporter family
KLHPDMAG_00873 9.4e-118 L Integrase
KLHPDMAG_00874 3e-156 rssA S Phospholipase, patatin family
KLHPDMAG_00875 1e-294 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
KLHPDMAG_00876 8.8e-15
KLHPDMAG_00878 1.5e-169 whiA K May be required for sporulation
KLHPDMAG_00879 2.1e-185 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KLHPDMAG_00880 4.9e-162 rapZ S Displays ATPase and GTPase activities
KLHPDMAG_00881 5.4e-245 steT E amino acid
KLHPDMAG_00882 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KLHPDMAG_00883 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KLHPDMAG_00884 1.5e-13
KLHPDMAG_00885 5.1e-116 yfbR S HD containing hydrolase-like enzyme
KLHPDMAG_00886 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
KLHPDMAG_00887 7.2e-89 ykhA 3.1.2.20 I Thioesterase superfamily
KLHPDMAG_00888 3.2e-161 aatB ET PFAM extracellular solute-binding protein, family 3
KLHPDMAG_00889 6.9e-204 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
KLHPDMAG_00890 3.9e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KLHPDMAG_00891 2.7e-168 lutA C Cysteine-rich domain
KLHPDMAG_00892 1.3e-292 lutB C 4Fe-4S dicluster domain
KLHPDMAG_00893 1.7e-136 yrjD S LUD domain
KLHPDMAG_00894 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KLHPDMAG_00895 8.5e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KLHPDMAG_00896 3.2e-155 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KLHPDMAG_00897 1.7e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KLHPDMAG_00898 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
KLHPDMAG_00899 7.7e-31 KT PspC domain protein
KLHPDMAG_00900 8.6e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KLHPDMAG_00901 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KLHPDMAG_00902 4.5e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KLHPDMAG_00903 3.9e-114 comFC S Competence protein
KLHPDMAG_00904 1.6e-249 comFA L Helicase C-terminal domain protein
KLHPDMAG_00905 1.1e-107 yvyE 3.4.13.9 S YigZ family
KLHPDMAG_00906 1.5e-91 2.3.1.183 M Acetyltransferase GNAT family
KLHPDMAG_00907 2.2e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KLHPDMAG_00908 6.4e-248 yxbA 6.3.1.12 S ATP-grasp enzyme
KLHPDMAG_00909 1.7e-290 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KLHPDMAG_00910 0.0 asnB 6.3.5.4 E Asparagine synthase
KLHPDMAG_00911 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KLHPDMAG_00912 2.8e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KLHPDMAG_00913 5.7e-130 jag S R3H domain protein
KLHPDMAG_00914 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KLHPDMAG_00915 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KLHPDMAG_00916 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
KLHPDMAG_00917 1.1e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KLHPDMAG_00918 2.6e-203 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KLHPDMAG_00919 1.7e-34 yaaA S S4 domain protein YaaA
KLHPDMAG_00920 1.3e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KLHPDMAG_00921 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KLHPDMAG_00922 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KLHPDMAG_00923 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
KLHPDMAG_00924 7.5e-79 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KLHPDMAG_00925 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KLHPDMAG_00926 8.4e-32 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KLHPDMAG_00927 1.2e-46 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KLHPDMAG_00928 2.6e-100 deoR K sugar-binding domain protein
KLHPDMAG_00929 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KLHPDMAG_00930 2e-74 rplI J Binds to the 23S rRNA
KLHPDMAG_00931 4.1e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KLHPDMAG_00932 9e-207 yttB EGP Major facilitator Superfamily
KLHPDMAG_00933 9.1e-61
KLHPDMAG_00934 2e-155 S Polyphosphate nucleotide phosphotransferase, PPK2 family
KLHPDMAG_00935 2.3e-253 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KLHPDMAG_00936 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KLHPDMAG_00937 3.9e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
KLHPDMAG_00938 1.1e-294 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KLHPDMAG_00940 3.2e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KLHPDMAG_00941 5.3e-209 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KLHPDMAG_00942 9.4e-62 L Toxic component of a toxin-antitoxin (TA) module
KLHPDMAG_00943 3.1e-251 U Belongs to the purine-cytosine permease (2.A.39) family
KLHPDMAG_00944 2.3e-242 codA 3.5.4.1 F cytosine deaminase
KLHPDMAG_00945 1.9e-144 tesE Q hydratase
KLHPDMAG_00946 1.1e-113 S (CBS) domain
KLHPDMAG_00947 1.3e-102 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KLHPDMAG_00948 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KLHPDMAG_00949 2.1e-39 yabO J S4 domain protein
KLHPDMAG_00950 1.6e-55 divIC D Septum formation initiator
KLHPDMAG_00951 9.8e-67 yabR J RNA binding
KLHPDMAG_00952 1.2e-250 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KLHPDMAG_00953 1.3e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KLHPDMAG_00954 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KLHPDMAG_00955 7.4e-169 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KLHPDMAG_00956 2.4e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KLHPDMAG_00957 4.7e-293 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KLHPDMAG_00958 2.5e-84
KLHPDMAG_00960 1.2e-76 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
KLHPDMAG_00961 3.7e-116 2.1.1.72, 3.1.21.4 V restriction endonuclease
KLHPDMAG_00962 0.0 L Type III restriction enzyme, res subunit
KLHPDMAG_00963 3e-284 S Protein of unknown function DUF262
KLHPDMAG_00966 1.3e-89 L Bacterial dnaA protein
KLHPDMAG_00967 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
KLHPDMAG_00968 8.7e-34 copZ C Heavy-metal-associated domain
KLHPDMAG_00969 5.7e-92 dps P Belongs to the Dps family
KLHPDMAG_00970 6.8e-113 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
KLHPDMAG_00971 1.7e-16 ung2 3.2.2.27 L Uracil-DNA glycosylase
KLHPDMAG_00972 2.9e-83 ung2 3.2.2.27 L Uracil-DNA glycosylase
KLHPDMAG_00973 3.6e-62 5.1.1.13 M Asp/Glu/Hydantoin racemase
KLHPDMAG_00974 4.9e-21 5.1.1.13 M Asp/Glu/Hydantoin racemase
KLHPDMAG_00975 1.2e-78 L Recombinase
KLHPDMAG_00976 9.8e-112 L Recombinase zinc beta ribbon domain
KLHPDMAG_00977 1.5e-69 L Recombinase zinc beta ribbon domain
KLHPDMAG_00978 2.8e-19
KLHPDMAG_00979 5.4e-55 S Bacteriophage holin family
KLHPDMAG_00980 6.5e-55 S Phage head-tail joining protein
KLHPDMAG_00981 4.6e-39 S Phage gp6-like head-tail connector protein
KLHPDMAG_00982 8.8e-172 S Phage capsid family
KLHPDMAG_00983 1.2e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KLHPDMAG_00984 1.1e-127 3.6.1.13, 3.6.1.55 F NUDIX domain
KLHPDMAG_00985 1e-257 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KLHPDMAG_00986 1.2e-102 pncA Q Isochorismatase family
KLHPDMAG_00987 3.7e-272 E ABC transporter, substratebinding protein
KLHPDMAG_00988 3.4e-145 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
KLHPDMAG_00989 2.2e-131 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KLHPDMAG_00990 4.9e-164 oppD P Belongs to the ABC transporter superfamily
KLHPDMAG_00991 3.8e-138 P Belongs to the ABC transporter superfamily
KLHPDMAG_00992 8.1e-160 Q Imidazolonepropionase and related amidohydrolases
KLHPDMAG_00993 1.3e-223 dap2 3.4.19.1 E Prolyl oligopeptidase family
KLHPDMAG_00994 2.4e-191 Q Imidazolonepropionase and related amidohydrolases
KLHPDMAG_00995 5.7e-218 dapE 3.5.1.18 E Peptidase dimerisation domain
KLHPDMAG_00996 9.9e-42 L Transposase and inactivated derivatives
KLHPDMAG_00997 1.1e-150 L Integrase core domain
KLHPDMAG_01003 8.8e-42
KLHPDMAG_01004 1.7e-102 L Integrase
KLHPDMAG_01005 2.3e-44
KLHPDMAG_01006 4.7e-55 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KLHPDMAG_01007 1.2e-121 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
KLHPDMAG_01008 1.1e-168 arsB 1.20.4.1 P Sodium Bile acid symporter family
KLHPDMAG_01009 1.3e-42 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
KLHPDMAG_01012 4.4e-88 D CobQ CobB MinD ParA nucleotide binding domain protein
KLHPDMAG_01013 1.8e-18 L Transposase
KLHPDMAG_01014 2.9e-134 L Transposase
KLHPDMAG_01015 0.0 rafA 3.2.1.22 G alpha-galactosidase
KLHPDMAG_01016 3.7e-185 galR K Periplasmic binding protein-like domain
KLHPDMAG_01017 2.2e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
KLHPDMAG_01018 8.1e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KLHPDMAG_01019 1.3e-45 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
KLHPDMAG_01020 1.2e-147 f42a O Band 7 protein
KLHPDMAG_01021 6.3e-257 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
KLHPDMAG_01022 2.7e-154 yitU 3.1.3.104 S hydrolase
KLHPDMAG_01023 9.2e-39 S Cytochrome B5
KLHPDMAG_01024 3.4e-115 nreC K PFAM regulatory protein LuxR
KLHPDMAG_01025 5.2e-159 hipB K Helix-turn-helix
KLHPDMAG_01026 2.8e-57 yitW S Iron-sulfur cluster assembly protein
KLHPDMAG_01027 1.2e-271 sufB O assembly protein SufB
KLHPDMAG_01028 3.6e-79 nifU C SUF system FeS assembly protein, NifU family
KLHPDMAG_01029 1.2e-233 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KLHPDMAG_01030 5.1e-240 sufD O FeS assembly protein SufD
KLHPDMAG_01031 1.9e-144 sufC O FeS assembly ATPase SufC
KLHPDMAG_01032 2.8e-31 feoA P FeoA domain
KLHPDMAG_01033 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
KLHPDMAG_01034 2.2e-268 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
KLHPDMAG_01035 2.9e-156 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KLHPDMAG_01036 3e-60 ydiI Q Thioesterase superfamily
KLHPDMAG_01037 7.3e-106 yvrI K sigma factor activity
KLHPDMAG_01038 1.7e-202 G Transporter, major facilitator family protein
KLHPDMAG_01039 0.0 S Bacterial membrane protein YfhO
KLHPDMAG_01040 1.2e-102 T Ion transport 2 domain protein
KLHPDMAG_01041 7.4e-77 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KLHPDMAG_01042 1.5e-225 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
KLHPDMAG_01043 2e-93 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
KLHPDMAG_01044 6.8e-182 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KLHPDMAG_01045 1.8e-178 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
KLHPDMAG_01047 0.0 L PLD-like domain
KLHPDMAG_01048 2e-89 mrr L restriction endonuclease
KLHPDMAG_01049 3.1e-167 L restriction endonuclease
KLHPDMAG_01050 1.1e-97 hsdS_1 3.1.21.3 V Type I restriction modification DNA specificity domain protein
KLHPDMAG_01051 4.4e-177 L Belongs to the 'phage' integrase family
KLHPDMAG_01052 1.3e-122 hsdS-1 3.1.21.3 L Type I restriction modification DNA specificity domain
KLHPDMAG_01053 9.1e-194 hsdM 2.1.1.72 V type I restriction-modification system
KLHPDMAG_01054 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
KLHPDMAG_01055 4.6e-15 IQ KR domain
KLHPDMAG_01057 7.9e-22 yhaI S Protein of unknown function (DUF805)
KLHPDMAG_01058 2.2e-44
KLHPDMAG_01059 1.6e-21
KLHPDMAG_01060 1.2e-46
KLHPDMAG_01061 2.9e-96 K Acetyltransferase (GNAT) domain
KLHPDMAG_01062 3e-292 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
KLHPDMAG_01063 7.8e-16 gntT EG Gluconate
KLHPDMAG_01064 1.6e-18
KLHPDMAG_01065 2.7e-189 ps461 3.5.1.104 M hydrolase, family 25
KLHPDMAG_01066 9.2e-34 S Bacteriophage holin of superfamily 6 (Holin_LLH)
KLHPDMAG_01067 1.2e-32
KLHPDMAG_01069 3.5e-48 E GDSL-like Lipase/Acylhydrolase
KLHPDMAG_01072 4.2e-219 M CHAP domain
KLHPDMAG_01073 1.4e-90 S Phage tail protein
KLHPDMAG_01074 1.3e-135 Z012_10445 D Phage tail tape measure protein
KLHPDMAG_01075 3.1e-13
KLHPDMAG_01076 3.8e-22 S Phage tail assembly chaperone protein, TAC
KLHPDMAG_01077 4.5e-40 S Phage tail tube protein
KLHPDMAG_01078 1.7e-29 S Protein of unknown function (DUF3168)
KLHPDMAG_01079 2.4e-30 S Bacteriophage HK97-gp10, putative tail-component
KLHPDMAG_01080 1.6e-35
KLHPDMAG_01081 1.5e-30 S Phage gp6-like head-tail connector protein
KLHPDMAG_01082 6.5e-123
KLHPDMAG_01083 2.6e-40 S Domain of unknown function (DUF4355)
KLHPDMAG_01086 2.9e-30 S sequence-specific DNA binding transcription factor activity
KLHPDMAG_01087 1.5e-62 S Phage Mu protein F like protein
KLHPDMAG_01088 1.4e-137 S Phage portal protein
KLHPDMAG_01089 8.1e-187 ps334 S Terminase-like family
KLHPDMAG_01090 4.2e-44
KLHPDMAG_01092 2.9e-15 arpU S Phage transcriptional regulator, ArpU family
KLHPDMAG_01093 2.5e-07
KLHPDMAG_01095 9.3e-32
KLHPDMAG_01096 1.3e-22
KLHPDMAG_01101 3.4e-80 Q DNA (cytosine-5-)-methyltransferase activity
KLHPDMAG_01102 8.7e-16
KLHPDMAG_01108 1e-34 S Protein of unknown function (DUF1064)
KLHPDMAG_01112 5.7e-40 dnaC 3.4.21.53 L IstB-like ATP binding protein
KLHPDMAG_01113 9.1e-65 ybl78 L DnaD domain protein
KLHPDMAG_01114 5.4e-21 L Single-stranded DNA-binding protein
KLHPDMAG_01115 9.3e-84 S Putative HNHc nuclease
KLHPDMAG_01116 1e-43 S ERF superfamily
KLHPDMAG_01120 4.9e-16
KLHPDMAG_01124 1.9e-82 S Phage antirepressor protein KilAC domain
KLHPDMAG_01125 1e-22 S sequence-specific DNA binding
KLHPDMAG_01127 5.7e-62
KLHPDMAG_01128 2.1e-63 V Abi-like protein
KLHPDMAG_01129 2.5e-235 int L COG1961 Site-specific recombinases, DNA invertase Pin homologs
KLHPDMAG_01130 9.4e-234 EGP Sugar (and other) transporter
KLHPDMAG_01131 3.9e-254 yfnA E Amino Acid
KLHPDMAG_01132 4.9e-72 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
KLHPDMAG_01133 7.1e-101 gmk2 2.7.4.8 F Guanylate kinase
KLHPDMAG_01134 1.1e-80 zur P Belongs to the Fur family
KLHPDMAG_01135 4e-17 3.2.1.14 GH18
KLHPDMAG_01136 2.7e-149
KLHPDMAG_01137 1.7e-38 pspC KT positive regulation of macromolecule biosynthetic process
KLHPDMAG_01138 1.6e-94 K Transcriptional regulator (TetR family)
KLHPDMAG_01139 1.3e-219 V domain protein
KLHPDMAG_01140 3.1e-176 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KLHPDMAG_01142 6.6e-35 S Transglycosylase associated protein
KLHPDMAG_01143 6e-225 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KLHPDMAG_01144 1.5e-126 3.1.3.73 G phosphoglycerate mutase
KLHPDMAG_01145 7e-113 dedA S SNARE associated Golgi protein
KLHPDMAG_01146 0.0 helD 3.6.4.12 L DNA helicase
KLHPDMAG_01147 2.8e-36 Q pyridine nucleotide-disulphide oxidoreductase
KLHPDMAG_01148 6.2e-157 EG EamA-like transporter family
KLHPDMAG_01149 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KLHPDMAG_01150 1.7e-176 coaA 2.7.1.33 F Pantothenic acid kinase
KLHPDMAG_01151 3e-218 S cog cog1373
KLHPDMAG_01153 6.2e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KLHPDMAG_01154 9.7e-283 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
KLHPDMAG_01155 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KLHPDMAG_01156 8.4e-171 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
KLHPDMAG_01157 6.8e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KLHPDMAG_01158 1.2e-126 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
KLHPDMAG_01159 2.3e-101 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
KLHPDMAG_01160 2e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KLHPDMAG_01161 1.3e-129 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KLHPDMAG_01162 4.5e-217 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KLHPDMAG_01163 8.4e-137 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KLHPDMAG_01164 5.6e-141 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
KLHPDMAG_01165 8.5e-226 mtnE 2.6.1.83 E Aminotransferase
KLHPDMAG_01166 2.3e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KLHPDMAG_01167 0.0 uup S ABC transporter, ATP-binding protein
KLHPDMAG_01168 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KLHPDMAG_01170 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KLHPDMAG_01171 5.5e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KLHPDMAG_01172 1.3e-79 S Aminoacyl-tRNA editing domain
KLHPDMAG_01173 2.6e-302 ybeC E amino acid
KLHPDMAG_01174 0.0 ydaO E amino acid
KLHPDMAG_01175 2.7e-39
KLHPDMAG_01176 2.9e-235 V MatE
KLHPDMAG_01177 5.6e-68 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
KLHPDMAG_01178 5.9e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KLHPDMAG_01179 1e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KLHPDMAG_01180 1.8e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KLHPDMAG_01181 5.3e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
KLHPDMAG_01182 6.7e-59 yodB K Transcriptional regulator, HxlR family
KLHPDMAG_01183 2.3e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KLHPDMAG_01184 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KLHPDMAG_01185 3.6e-114 rlpA M PFAM NLP P60 protein
KLHPDMAG_01186 8e-117 udk 2.7.1.48 F Cytidine monophosphokinase
KLHPDMAG_01187 5.3e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KLHPDMAG_01188 4.1e-68 yneR S Belongs to the HesB IscA family
KLHPDMAG_01189 0.0 S membrane
KLHPDMAG_01190 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
KLHPDMAG_01191 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KLHPDMAG_01192 1.8e-101 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KLHPDMAG_01193 1.6e-74 gluP 3.4.21.105 S Peptidase, S54 family
KLHPDMAG_01194 1.6e-19 gluP 3.4.21.105 S Peptidase, S54 family
KLHPDMAG_01195 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
KLHPDMAG_01196 5.6e-183 glk 2.7.1.2 G Glucokinase
KLHPDMAG_01197 3.4e-67 yqhL P Rhodanese-like protein
KLHPDMAG_01198 5.9e-22 S Protein of unknown function (DUF3042)
KLHPDMAG_01199 1.4e-170 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KLHPDMAG_01200 8.1e-265 glnA 6.3.1.2 E glutamine synthetase
KLHPDMAG_01201 4.9e-295 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KLHPDMAG_01202 1.3e-33 ywzB S Protein of unknown function (DUF1146)
KLHPDMAG_01203 1e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KLHPDMAG_01204 1.9e-178 mbl D Cell shape determining protein MreB Mrl
KLHPDMAG_01205 4.4e-41 yidD S Could be involved in insertion of integral membrane proteins into the membrane
KLHPDMAG_01206 1e-31 S Protein of unknown function (DUF2969)
KLHPDMAG_01207 1.1e-220 rodA D Belongs to the SEDS family
KLHPDMAG_01208 1.5e-46 gcvH E glycine cleavage
KLHPDMAG_01209 5.3e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KLHPDMAG_01210 3.7e-146 2.3.1.19 K Helix-turn-helix XRE-family like proteins
KLHPDMAG_01211 1.2e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KLHPDMAG_01212 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
KLHPDMAG_01213 1.4e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
KLHPDMAG_01214 1.4e-283 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
KLHPDMAG_01215 2.4e-90 maa 2.3.1.79 S Maltose O-acetyltransferase
KLHPDMAG_01216 2.5e-155 ytbE 1.1.1.346 S Aldo keto reductase
KLHPDMAG_01217 5.9e-205 araR K Transcriptional regulator
KLHPDMAG_01218 4.3e-83 usp6 T universal stress protein
KLHPDMAG_01219 4.4e-46
KLHPDMAG_01220 1.4e-234 rarA L recombination factor protein RarA
KLHPDMAG_01221 2.7e-85 yueI S Protein of unknown function (DUF1694)
KLHPDMAG_01222 1.2e-16
KLHPDMAG_01223 8.1e-75 4.4.1.5 E Glyoxalase
KLHPDMAG_01224 1.2e-137 S Membrane
KLHPDMAG_01225 1e-139 S Belongs to the UPF0246 family
KLHPDMAG_01226 3e-193 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
KLHPDMAG_01227 1.1e-33 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
KLHPDMAG_01228 4.9e-31 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
KLHPDMAG_01229 7.8e-24 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
KLHPDMAG_01230 7.9e-253 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KLHPDMAG_01231 1.4e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KLHPDMAG_01232 7.5e-158 htpX O Belongs to the peptidase M48B family
KLHPDMAG_01233 7e-93 lemA S LemA family
KLHPDMAG_01234 8e-87 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KLHPDMAG_01235 2.7e-120 pgm3 3.1.3.73 G Belongs to the phosphoglycerate mutase family
KLHPDMAG_01236 1.3e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
KLHPDMAG_01237 9.8e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KLHPDMAG_01238 1.8e-158 3.2.1.55 GH51 G Right handed beta helix region
KLHPDMAG_01239 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
KLHPDMAG_01240 7.3e-116 srtA 3.4.22.70 M sortase family
KLHPDMAG_01241 3.1e-164 S Alpha/beta hydrolase of unknown function (DUF915)
KLHPDMAG_01242 1.6e-236 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KLHPDMAG_01243 4.6e-41 rpmE2 J Ribosomal protein L31
KLHPDMAG_01244 2e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KLHPDMAG_01245 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KLHPDMAG_01246 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KLHPDMAG_01247 5.2e-53 ywiB S Domain of unknown function (DUF1934)
KLHPDMAG_01248 1e-23
KLHPDMAG_01249 3.1e-101 V VanZ like family
KLHPDMAG_01250 2.2e-230 cycA E Amino acid permease
KLHPDMAG_01251 6.2e-84 perR P Belongs to the Fur family
KLHPDMAG_01252 7.9e-258 EGP Major facilitator Superfamily
KLHPDMAG_01253 1.5e-92 tag 3.2.2.20 L glycosylase
KLHPDMAG_01254 1.9e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KLHPDMAG_01255 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KLHPDMAG_01256 6.4e-41
KLHPDMAG_01257 3.5e-302 ytgP S Polysaccharide biosynthesis protein
KLHPDMAG_01258 2.7e-152 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KLHPDMAG_01259 2.8e-276 pepV 3.5.1.18 E dipeptidase PepV
KLHPDMAG_01260 7.3e-86 uspA T Belongs to the universal stress protein A family
KLHPDMAG_01261 1.2e-175 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KLHPDMAG_01262 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
KLHPDMAG_01263 2.5e-112
KLHPDMAG_01264 7.4e-186 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
KLHPDMAG_01265 1.4e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KLHPDMAG_01266 1.2e-22 T Toxin-antitoxin system, toxin component, MazF family
KLHPDMAG_01267 7.5e-36
KLHPDMAG_01269 3.6e-188 snf 2.7.11.1 KL domain protein
KLHPDMAG_01270 0.0 snf 2.7.11.1 KL domain protein
KLHPDMAG_01271 1.2e-143 ywqE 3.1.3.48 GM PHP domain protein
KLHPDMAG_01272 1.2e-205 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KLHPDMAG_01273 0.0 sbcC L Putative exonuclease SbcCD, C subunit
KLHPDMAG_01274 1.4e-107 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
KLHPDMAG_01275 3.9e-143 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
KLHPDMAG_01276 5.6e-71
KLHPDMAG_01277 5.7e-103 fic D Fic/DOC family
KLHPDMAG_01278 8.1e-123 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KLHPDMAG_01279 7.5e-49 3.1.3.73 G Belongs to the phosphoglycerate mutase family
KLHPDMAG_01280 1.9e-83 3.1.3.73 G Belongs to the phosphoglycerate mutase family
KLHPDMAG_01281 7.9e-31
KLHPDMAG_01282 9.5e-59
KLHPDMAG_01283 2.1e-24
KLHPDMAG_01285 2.6e-258 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KLHPDMAG_01286 4.3e-186 yegS 2.7.1.107 G Lipid kinase
KLHPDMAG_01287 1.8e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KLHPDMAG_01288 7.7e-277 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KLHPDMAG_01289 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KLHPDMAG_01290 3.3e-203 camS S sex pheromone
KLHPDMAG_01291 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KLHPDMAG_01292 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KLHPDMAG_01293 1.1e-209 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KLHPDMAG_01294 2.3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KLHPDMAG_01295 3e-113 acmC 3.2.1.96 NU mannosyl-glycoprotein
KLHPDMAG_01296 8e-140 IQ reductase
KLHPDMAG_01297 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
KLHPDMAG_01298 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KLHPDMAG_01299 4.7e-94 2.3.1.128 K Acetyltransferase (GNAT) domain
KLHPDMAG_01300 2.7e-153 lmrB EGP Major facilitator Superfamily
KLHPDMAG_01301 1.6e-62 lmrB EGP Major facilitator Superfamily
KLHPDMAG_01302 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
KLHPDMAG_01303 7.6e-111 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KLHPDMAG_01304 1e-159 sufD O Uncharacterized protein family (UPF0051)
KLHPDMAG_01305 2e-42 lytE M LysM domain protein
KLHPDMAG_01306 0.0 oppD EP Psort location Cytoplasmic, score
KLHPDMAG_01307 7.3e-84 lytE M LysM domain protein
KLHPDMAG_01308 3.9e-147 xth 3.1.11.2 L exodeoxyribonuclease III
KLHPDMAG_01309 6.2e-235 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
KLHPDMAG_01310 5.3e-237 preA 1.3.1.1 C 4Fe-4S dicluster domain
KLHPDMAG_01311 5.3e-153 yeaE S Aldo keto
KLHPDMAG_01312 2e-76 hsp O Belongs to the small heat shock protein (HSP20) family
KLHPDMAG_01313 3e-209 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KLHPDMAG_01314 8.4e-182 ccpA K catabolite control protein A
KLHPDMAG_01315 4.9e-135
KLHPDMAG_01316 3.5e-132 yebC K Transcriptional regulatory protein
KLHPDMAG_01317 1.7e-179 comGA NU Type II IV secretion system protein
KLHPDMAG_01318 1.1e-179 comGB NU type II secretion system
KLHPDMAG_01319 7.1e-47 comGC U competence protein ComGC
KLHPDMAG_01320 2.4e-77 NU general secretion pathway protein
KLHPDMAG_01321 7.9e-40
KLHPDMAG_01322 1e-67
KLHPDMAG_01324 9.4e-144 ytxK 2.1.1.72 L N-6 DNA Methylase
KLHPDMAG_01325 1.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KLHPDMAG_01326 2.1e-111 S Calcineurin-like phosphoesterase
KLHPDMAG_01327 6.6e-93 yutD S Protein of unknown function (DUF1027)
KLHPDMAG_01328 9.4e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KLHPDMAG_01329 1.5e-102 S Protein of unknown function (DUF1461)
KLHPDMAG_01330 1.6e-109 dedA S SNARE-like domain protein
KLHPDMAG_01331 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
KLHPDMAG_01332 2.4e-53 ysxB J Cysteine protease Prp
KLHPDMAG_01333 1.3e-44 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KLHPDMAG_01334 8.9e-130 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KLHPDMAG_01335 3.3e-200 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KLHPDMAG_01336 1e-114 J 2'-5' RNA ligase superfamily
KLHPDMAG_01337 2.2e-70 yqhY S Asp23 family, cell envelope-related function
KLHPDMAG_01338 4.7e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KLHPDMAG_01339 4e-148 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KLHPDMAG_01340 2.3e-211 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KLHPDMAG_01341 1.3e-42 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KLHPDMAG_01342 6.4e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KLHPDMAG_01343 3.4e-149 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
KLHPDMAG_01344 1.6e-76 argR K Regulates arginine biosynthesis genes
KLHPDMAG_01345 5.5e-263 recN L May be involved in recombinational repair of damaged DNA
KLHPDMAG_01346 4.2e-53
KLHPDMAG_01347 3.5e-114 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KLHPDMAG_01348 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KLHPDMAG_01349 1.3e-208 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KLHPDMAG_01350 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KLHPDMAG_01351 1.1e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KLHPDMAG_01352 2.4e-248 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KLHPDMAG_01353 1.8e-128 stp 3.1.3.16 T phosphatase
KLHPDMAG_01354 0.0 KLT serine threonine protein kinase
KLHPDMAG_01355 2.5e-161 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KLHPDMAG_01356 9.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KLHPDMAG_01357 2.4e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
KLHPDMAG_01358 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KLHPDMAG_01359 4.7e-58 asp S Asp23 family, cell envelope-related function
KLHPDMAG_01360 0.0 yloV S DAK2 domain fusion protein YloV
KLHPDMAG_01361 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KLHPDMAG_01362 1e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KLHPDMAG_01363 1.4e-37 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KLHPDMAG_01364 1.2e-131 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KLHPDMAG_01365 0.0 smc D Required for chromosome condensation and partitioning
KLHPDMAG_01366 6.5e-178 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KLHPDMAG_01367 3.7e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KLHPDMAG_01368 1.8e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KLHPDMAG_01369 6.5e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KLHPDMAG_01370 7e-40 ylqC S Belongs to the UPF0109 family
KLHPDMAG_01371 7.6e-91 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KLHPDMAG_01372 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KLHPDMAG_01373 4.6e-258 yfnA E amino acid
KLHPDMAG_01374 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KLHPDMAG_01375 8.5e-34
KLHPDMAG_01376 1.2e-52 S Mazg nucleotide pyrophosphohydrolase
KLHPDMAG_01377 3.3e-160 xth 3.1.11.2 L exodeoxyribonuclease III
KLHPDMAG_01378 2.2e-13
KLHPDMAG_01379 1.8e-184 lacR K Transcriptional regulator
KLHPDMAG_01380 0.0 lacS G Transporter
KLHPDMAG_01381 0.0 lacZ 3.2.1.23 G -beta-galactosidase
KLHPDMAG_01382 3.2e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KLHPDMAG_01383 6.8e-159 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
KLHPDMAG_01384 4.8e-142 XK27_00940 1.2.1.70, 3.5.1.9 S Putative cyclase
KLHPDMAG_01385 1e-96 yxjG_1 E methionine synthase, vitamin-B12 independent
KLHPDMAG_01386 2.6e-129 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KLHPDMAG_01387 1.4e-223 mdtG EGP Major facilitator Superfamily
KLHPDMAG_01388 1.7e-167 T Calcineurin-like phosphoesterase superfamily domain
KLHPDMAG_01389 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KLHPDMAG_01390 8.6e-50 L Transposase IS200 like
KLHPDMAG_01391 2.5e-185 L transposase, IS605 OrfB family
KLHPDMAG_01394 3.5e-120 sdaAB 4.3.1.17 E Serine dehydratase beta chain
KLHPDMAG_01395 9.7e-142 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
KLHPDMAG_01396 3.6e-105 ahpC 1.11.1.15 O Peroxiredoxin
KLHPDMAG_01397 0.0 trxB2 1.8.1.9 C Thioredoxin domain
KLHPDMAG_01398 1.2e-274 pipD E Dipeptidase
KLHPDMAG_01399 7.1e-296 yjbQ P TrkA C-terminal domain protein
KLHPDMAG_01400 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
KLHPDMAG_01401 2.5e-291 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KLHPDMAG_01402 1.1e-89
KLHPDMAG_01403 1.8e-34
KLHPDMAG_01404 5.6e-59 K DNA-templated transcription, initiation
KLHPDMAG_01405 1.5e-40 K Transcriptional regulator, HxlR family
KLHPDMAG_01406 7.6e-167 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KLHPDMAG_01407 3.2e-145 epsB M biosynthesis protein
KLHPDMAG_01408 1.5e-119 ywqD 2.7.10.1 D Capsular exopolysaccharide family
KLHPDMAG_01409 4.4e-51 pglC M sugar transferase
KLHPDMAG_01410 1.2e-74 wceM M Glycosyltransferase like family 2
KLHPDMAG_01411 2.4e-76 glfT1 1.1.1.133 S Glycosyltransferase like family 2
KLHPDMAG_01412 4.6e-96 M Glycosyltransferase, group 1 family protein
KLHPDMAG_01413 3.7e-60 M Domain of unknown function (DUF4422)
KLHPDMAG_01414 6.7e-19
KLHPDMAG_01415 2.3e-106 S Core-2/I-Branching enzyme
KLHPDMAG_01416 2e-216 glf 5.4.99.9 M UDP-galactopyranose mutase
KLHPDMAG_01417 7.8e-181 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
KLHPDMAG_01418 8e-182 iunH2 3.2.2.1 F nucleoside hydrolase
KLHPDMAG_01419 4.9e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
KLHPDMAG_01420 4.6e-35 3.6.4.12 S PD-(D/E)XK nuclease family transposase
KLHPDMAG_01421 2.4e-96 3.6.4.12 S PD-(D/E)XK nuclease family transposase
KLHPDMAG_01422 4.8e-114 gph 3.1.3.18 S HAD hydrolase, family IA, variant
KLHPDMAG_01423 9.7e-178 yagE E amino acid
KLHPDMAG_01424 9.2e-23 yagE E amino acid
KLHPDMAG_01425 3.4e-85 dps P Belongs to the Dps family
KLHPDMAG_01426 0.0 pacL 3.6.3.8 P P-type ATPase
KLHPDMAG_01427 6.7e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
KLHPDMAG_01428 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KLHPDMAG_01429 1.3e-36 2.7.7.65 T GGDEF domain
KLHPDMAG_01430 4.8e-22
KLHPDMAG_01431 7.5e-247 pgaC GT2 M Glycosyl transferase
KLHPDMAG_01432 3.5e-138 T EAL domain
KLHPDMAG_01433 7.2e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
KLHPDMAG_01434 4.2e-59 yneR
KLHPDMAG_01435 3.6e-101 qorB 1.6.5.2 GM NmrA-like family
KLHPDMAG_01436 3.6e-157 akr5f 1.1.1.346 S reductase
KLHPDMAG_01437 2.4e-140 K Transcriptional regulator
KLHPDMAG_01438 6.7e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
KLHPDMAG_01439 2.3e-155 ypuA S Protein of unknown function (DUF1002)
KLHPDMAG_01440 1.1e-228 aadAT EK Aminotransferase, class I
KLHPDMAG_01441 6.5e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KLHPDMAG_01442 6e-154 tesE Q hydratase
KLHPDMAG_01443 9.8e-36 S Alpha beta hydrolase
KLHPDMAG_01444 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
KLHPDMAG_01445 5.8e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KLHPDMAG_01446 3.2e-101 ypsA S Belongs to the UPF0398 family
KLHPDMAG_01447 1.2e-42 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KLHPDMAG_01448 8e-82 F Belongs to the NrdI family
KLHPDMAG_01449 1.1e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KLHPDMAG_01450 9e-71 rnhA 3.1.26.4 L Ribonuclease HI
KLHPDMAG_01451 5.6e-65 esbA S Family of unknown function (DUF5322)
KLHPDMAG_01452 1.7e-73 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KLHPDMAG_01453 2.2e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KLHPDMAG_01454 1.4e-206 carA 6.3.5.5 F Belongs to the CarA family
KLHPDMAG_01455 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
KLHPDMAG_01456 1.6e-199 xerS L Belongs to the 'phage' integrase family
KLHPDMAG_01458 1.1e-69 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KLHPDMAG_01459 4.7e-76 marR K Transcriptional regulator, MarR family
KLHPDMAG_01460 1.8e-168 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KLHPDMAG_01461 1.4e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KLHPDMAG_01462 2.4e-154 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
KLHPDMAG_01463 4.3e-127 IQ reductase
KLHPDMAG_01464 3e-221 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KLHPDMAG_01465 2.5e-69 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KLHPDMAG_01466 4e-72 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KLHPDMAG_01467 5.2e-259 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
KLHPDMAG_01468 2.3e-140 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KLHPDMAG_01469 8.3e-137 accA 2.1.3.15, 6.4.1.2 I alpha subunit
KLHPDMAG_01470 1.6e-129 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
KLHPDMAG_01475 6.3e-257 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KLHPDMAG_01476 5e-182 pbuG S permease
KLHPDMAG_01477 1.4e-163 add 3.5.4.2, 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KLHPDMAG_01478 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
KLHPDMAG_01479 2.5e-258 G Major Facilitator Superfamily
KLHPDMAG_01480 1.8e-34 2.1.1.72 V Type II restriction enzyme, methylase subunits
KLHPDMAG_01481 5.5e-174 2.1.1.72 V Type II restriction enzyme, methylase subunits
KLHPDMAG_01482 9.9e-225 oxlT P Major Facilitator Superfamily
KLHPDMAG_01483 3.4e-149 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
KLHPDMAG_01484 1e-270 ywfO S HD domain protein
KLHPDMAG_01485 6.1e-146 yxeH S hydrolase
KLHPDMAG_01486 9e-48
KLHPDMAG_01487 4.2e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KLHPDMAG_01488 9.2e-240 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KLHPDMAG_01489 6.9e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
KLHPDMAG_01490 1.4e-126 znuB U ABC 3 transport family
KLHPDMAG_01491 1.4e-121 fhuC P ABC transporter
KLHPDMAG_01492 9e-167 znuA P Belongs to the bacterial solute-binding protein 9 family
KLHPDMAG_01493 3.1e-161 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KLHPDMAG_01494 9.8e-163 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KLHPDMAG_01495 4.2e-109 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KLHPDMAG_01496 1.9e-197 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KLHPDMAG_01497 3e-156 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KLHPDMAG_01498 0.0 csd1 3.5.1.28 G domain, Protein
KLHPDMAG_01499 7.4e-163 yueF S AI-2E family transporter
KLHPDMAG_01500 2.3e-262 L PFAM Integrase catalytic region
KLHPDMAG_01501 2.4e-222 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KLHPDMAG_01502 4e-50 3.2.1.4 GH5,GH9 M domain protein
KLHPDMAG_01503 3.5e-103 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
KLHPDMAG_01504 5.2e-56 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
KLHPDMAG_01505 1.4e-43 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
KLHPDMAG_01506 1.3e-43 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
KLHPDMAG_01507 6.9e-108 T Transcriptional regulatory protein, C terminal
KLHPDMAG_01508 5.1e-83 T GHKL domain
KLHPDMAG_01509 4.8e-118 T GHKL domain
KLHPDMAG_01510 7.8e-77 S Peptidase propeptide and YPEB domain
KLHPDMAG_01511 4.7e-17 P nitric oxide dioxygenase activity
KLHPDMAG_01512 6.1e-45 lacA S transferase hexapeptide repeat
KLHPDMAG_01513 9.9e-81 S Alpha beta hydrolase
KLHPDMAG_01514 1.8e-09
KLHPDMAG_01515 5.8e-88 doc
KLHPDMAG_01516 1.1e-29 S Protein of unknown function (DUF4065)
KLHPDMAG_01518 6.4e-54 YPO0284 GM NAD(P)H-binding
KLHPDMAG_01519 2.3e-17
KLHPDMAG_01520 8.9e-70
KLHPDMAG_01523 5.2e-224 O Subtilase family
KLHPDMAG_01524 5.3e-123 O Holliday junction DNA helicase ruvB N-terminus
KLHPDMAG_01525 3.4e-51 yfnA E Amino Acid
KLHPDMAG_01526 3.2e-65 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KLHPDMAG_01527 1.4e-54 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KLHPDMAG_01528 5.3e-64 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KLHPDMAG_01529 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KLHPDMAG_01530 1.1e-297 mco Q Multicopper oxidase
KLHPDMAG_01531 8.9e-89 L PFAM Integrase catalytic region
KLHPDMAG_01533 5.6e-119 Z012_01130 S Fic/DOC family
KLHPDMAG_01536 1.8e-72 K helix_turn_helix multiple antibiotic resistance protein
KLHPDMAG_01537 6.6e-304 lmrA 3.6.3.44 V ABC transporter
KLHPDMAG_01539 3.1e-130 K response regulator
KLHPDMAG_01540 0.0 vicK 2.7.13.3 T Histidine kinase
KLHPDMAG_01541 7.6e-244 yycH S YycH protein
KLHPDMAG_01542 1.7e-148 yycI S YycH protein
KLHPDMAG_01543 2.9e-153 vicX 3.1.26.11 S domain protein
KLHPDMAG_01544 1.6e-214 htrA 3.4.21.107 O serine protease
KLHPDMAG_01545 5.9e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
KLHPDMAG_01546 1.5e-175 ABC-SBP S ABC transporter
KLHPDMAG_01547 1.8e-87 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KLHPDMAG_01549 2.4e-95 S reductase
KLHPDMAG_01550 4.9e-226 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
KLHPDMAG_01551 7.5e-155 glcU U sugar transport
KLHPDMAG_01552 8.3e-145 E Glyoxalase-like domain
KLHPDMAG_01553 3e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KLHPDMAG_01554 4e-259 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
KLHPDMAG_01555 7e-142 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KLHPDMAG_01556 2.8e-128 V ABC transporter
KLHPDMAG_01557 1.5e-212 bacI V MacB-like periplasmic core domain
KLHPDMAG_01558 1.2e-38
KLHPDMAG_01559 4e-259 S Putative peptidoglycan binding domain
KLHPDMAG_01562 1.2e-08 2.7.13.3 T GHKL domain
KLHPDMAG_01563 8.7e-54 L An automated process has identified a potential problem with this gene model
KLHPDMAG_01564 3.6e-85 K FR47-like protein
KLHPDMAG_01565 6.2e-120 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
KLHPDMAG_01568 5e-75 osmC O OsmC-like protein
KLHPDMAG_01569 3.2e-173 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KLHPDMAG_01570 1.2e-214 patA 2.6.1.1 E Aminotransferase
KLHPDMAG_01571 7.8e-32
KLHPDMAG_01572 0.0 clpL O associated with various cellular activities
KLHPDMAG_01574 3.1e-104 wecD3 K PFAM GCN5-related N-acetyltransferase
KLHPDMAG_01575 8.5e-284 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KLHPDMAG_01576 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
KLHPDMAG_01577 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KLHPDMAG_01578 1.5e-172 malR K Transcriptional regulator, LacI family
KLHPDMAG_01579 3.7e-213 phbA 2.3.1.9 I Belongs to the thiolase family
KLHPDMAG_01580 3.1e-256 malT G Major Facilitator
KLHPDMAG_01581 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
KLHPDMAG_01582 5.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
KLHPDMAG_01583 2e-71
KLHPDMAG_01584 1.8e-86 2.7.6.5 T Region found in RelA / SpoT proteins
KLHPDMAG_01585 3.3e-118 K response regulator
KLHPDMAG_01586 3.1e-226 sptS 2.7.13.3 T Histidine kinase
KLHPDMAG_01587 1.8e-212 yfeO P Voltage gated chloride channel
KLHPDMAG_01588 5.2e-220 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
KLHPDMAG_01589 6.6e-136 puuD S peptidase C26
KLHPDMAG_01590 5.9e-168 yvgN C Aldo keto reductase
KLHPDMAG_01591 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
KLHPDMAG_01592 3e-87 hmpT S ECF-type riboflavin transporter, S component
KLHPDMAG_01593 1.7e-262 nox C NADH oxidase
KLHPDMAG_01594 9.9e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KLHPDMAG_01595 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KLHPDMAG_01596 3.9e-78
KLHPDMAG_01597 4.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KLHPDMAG_01599 9.3e-13 steT_1 E amino acid
KLHPDMAG_01600 4.3e-13 K Transcriptional regulator, TetR family
KLHPDMAG_01601 3.4e-74 K Transcriptional regulator, TetR family
KLHPDMAG_01602 8.3e-72
KLHPDMAG_01603 1.5e-267 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
KLHPDMAG_01604 6.5e-271 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
KLHPDMAG_01605 2.4e-266 M protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
KLHPDMAG_01606 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
KLHPDMAG_01607 3.7e-265 G Major Facilitator
KLHPDMAG_01608 1.3e-160 EG EamA-like transporter family
KLHPDMAG_01609 8.1e-123 dnaD L DnaD domain protein
KLHPDMAG_01610 9.9e-86 ypmB S Protein conserved in bacteria
KLHPDMAG_01611 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KLHPDMAG_01612 6.3e-171 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
KLHPDMAG_01613 3.7e-166 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
KLHPDMAG_01614 2.1e-213 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
KLHPDMAG_01615 3.2e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KLHPDMAG_01616 1.7e-84 S Protein of unknown function (DUF1440)
KLHPDMAG_01617 2.4e-36 L Transposase
KLHPDMAG_01619 1.4e-192
KLHPDMAG_01620 5.2e-98 2.3.1.128 K acetyltransferase
KLHPDMAG_01621 6.1e-111 manA 5.3.1.8 G mannose-6-phosphate isomerase
KLHPDMAG_01622 2e-155 K LysR substrate binding domain
KLHPDMAG_01623 3e-122 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
KLHPDMAG_01624 3.3e-72 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
KLHPDMAG_01625 6.2e-54 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KLHPDMAG_01626 1.5e-181
KLHPDMAG_01627 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KLHPDMAG_01628 1.4e-160 S Phosphotransferase system, EIIC
KLHPDMAG_01629 8.4e-127 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
KLHPDMAG_01631 1.2e-54 repB EP Plasmid replication protein
KLHPDMAG_01633 1e-43 vsr L DNA mismatch endonuclease Vsr
KLHPDMAG_01634 2.6e-145 dcm 2.1.1.37 H cytosine-specific methyltransferase
KLHPDMAG_01635 5.4e-124
KLHPDMAG_01636 2.1e-71 L Integrase
KLHPDMAG_01638 0.0 clpE O Belongs to the ClpA ClpB family
KLHPDMAG_01639 2.4e-26
KLHPDMAG_01640 2.7e-39 ptsH G phosphocarrier protein HPR
KLHPDMAG_01641 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KLHPDMAG_01642 3.9e-226 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
KLHPDMAG_01643 2.2e-198 cpoA GT4 M Glycosyltransferase, group 1 family protein
KLHPDMAG_01644 1.9e-178 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KLHPDMAG_01645 1.3e-38 ykuJ S Protein of unknown function (DUF1797)
KLHPDMAG_01646 0.0 bamA GM domain, Protein
KLHPDMAG_01647 6e-64 gntR1 K Transcriptional regulator, GntR family
KLHPDMAG_01648 2.3e-156 V ABC transporter, ATP-binding protein
KLHPDMAG_01649 1e-114
KLHPDMAG_01650 3e-141 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
KLHPDMAG_01651 1.7e-100 S Pfam:DUF3816
KLHPDMAG_01652 8.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
KLHPDMAG_01653 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KLHPDMAG_01654 6.7e-119 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KLHPDMAG_01655 1.8e-195 coiA 3.6.4.12 S Competence protein
KLHPDMAG_01656 6.8e-267 pipD E Dipeptidase
KLHPDMAG_01657 3.1e-113 yjbH Q Thioredoxin
KLHPDMAG_01658 2e-115 yjbM 2.7.6.5 S RelA SpoT domain protein
KLHPDMAG_01659 5.1e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KLHPDMAG_01660 1e-170 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
KLHPDMAG_01661 2.3e-107 mod_1 2.1.1.72 L Adenine specific DNA methylase Mod
KLHPDMAG_01662 2.6e-40
KLHPDMAG_01663 7.2e-153 D CobQ CobB MinD ParA nucleotide binding domain protein
KLHPDMAG_01664 0.0
KLHPDMAG_01666 2.3e-44
KLHPDMAG_01667 1.7e-33 S RelB antitoxin
KLHPDMAG_01668 9.1e-104 L Integrase
KLHPDMAG_01669 2.8e-193 V Beta-lactamase
KLHPDMAG_01670 6e-94 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KLHPDMAG_01671 5.4e-95 yhiD S MgtC family
KLHPDMAG_01672 1.5e-115 S GyrI-like small molecule binding domain
KLHPDMAG_01673 7.3e-110 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
KLHPDMAG_01674 3.2e-50 azlD E Branched-chain amino acid transport
KLHPDMAG_01675 1.3e-117 azlC E azaleucine resistance protein AzlC
KLHPDMAG_01676 1.1e-259 K Aminotransferase class I and II
KLHPDMAG_01677 7.1e-130 S amidohydrolase
KLHPDMAG_01678 3.6e-46 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
KLHPDMAG_01679 2.8e-140 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
KLHPDMAG_01680 3.9e-12
KLHPDMAG_01681 5.7e-155 P Belongs to the nlpA lipoprotein family
KLHPDMAG_01682 3e-98 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KLHPDMAG_01683 4.8e-51 S Iron-sulfur cluster assembly protein
KLHPDMAG_01684 2.6e-150
KLHPDMAG_01685 1.2e-180
KLHPDMAG_01686 2.8e-85 dut S Protein conserved in bacteria
KLHPDMAG_01690 2.1e-103 K Transcriptional regulator
KLHPDMAG_01691 4.4e-55 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
KLHPDMAG_01692 3.6e-49 D nuclear chromosome segregation
KLHPDMAG_01693 1.7e-36
KLHPDMAG_01694 4.7e-171 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
KLHPDMAG_01695 2.9e-249 mmuP E amino acid
KLHPDMAG_01697 1.9e-273 S ABC transporter, ATP-binding protein
KLHPDMAG_01698 4.9e-18 K Helix-turn-helix domain
KLHPDMAG_01701 1.6e-90 S PAS domain
KLHPDMAG_01702 6e-62 macB_3 V FtsX-like permease family
KLHPDMAG_01703 5.4e-175 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KLHPDMAG_01704 1.9e-245 emrY EGP Major facilitator Superfamily
KLHPDMAG_01705 3.2e-45 ywfI S Chlorite dismutase
KLHPDMAG_01706 5.3e-57 ywfI S Chlorite dismutase
KLHPDMAG_01707 3.6e-257 gor 1.8.1.7 C Glutathione reductase
KLHPDMAG_01708 3.7e-11 K Transcriptional
KLHPDMAG_01709 9.9e-51 L Integrase
KLHPDMAG_01710 2.1e-56 L PFAM Integrase catalytic region
KLHPDMAG_01711 2.4e-63 L PFAM Integrase catalytic region
KLHPDMAG_01712 2.3e-73 M PFAM NLP P60 protein
KLHPDMAG_01713 1.1e-181 ABC-SBP S ABC transporter
KLHPDMAG_01714 3.3e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
KLHPDMAG_01715 1.2e-135 XK27_08845 S ABC transporter, ATP-binding protein
KLHPDMAG_01716 5.1e-96 P Cadmium resistance transporter
KLHPDMAG_01717 9.9e-55 K Transcriptional regulator, ArsR family
KLHPDMAG_01718 1.1e-234 mepA V MATE efflux family protein
KLHPDMAG_01719 3.2e-55 trxA O Belongs to the thioredoxin family
KLHPDMAG_01720 6.6e-131 terC P membrane
KLHPDMAG_01721 6.3e-168 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KLHPDMAG_01722 2.8e-168 corA P CorA-like Mg2+ transporter protein
KLHPDMAG_01723 4.3e-280 pipD E Dipeptidase
KLHPDMAG_01724 2.1e-241 pbuX F xanthine permease
KLHPDMAG_01725 5.9e-250 nhaC C Na H antiporter NhaC
KLHPDMAG_01726 4e-49 S C4-dicarboxylate anaerobic carrier
KLHPDMAG_01727 2.7e-125 pgm3 3.1.3.73 G phosphoglycerate mutase family
KLHPDMAG_01728 2.3e-38
KLHPDMAG_01729 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KLHPDMAG_01730 8.4e-207 gldA 1.1.1.6 C dehydrogenase
KLHPDMAG_01731 5.3e-121 S Alpha beta hydrolase
KLHPDMAG_01732 3.1e-215 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KLHPDMAG_01733 3.7e-97
KLHPDMAG_01735 1.3e-122 yciB M ErfK YbiS YcfS YnhG
KLHPDMAG_01736 1.2e-260 S Putative peptidoglycan binding domain
KLHPDMAG_01737 3e-108 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
KLHPDMAG_01738 1e-87
KLHPDMAG_01739 8.8e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
KLHPDMAG_01740 4.1e-212 yttB EGP Major facilitator Superfamily
KLHPDMAG_01741 8.2e-103
KLHPDMAG_01742 3.9e-24
KLHPDMAG_01743 1.8e-173 scrR K Transcriptional regulator, LacI family
KLHPDMAG_01744 2.5e-239 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KLHPDMAG_01745 2.5e-36
KLHPDMAG_01746 0.0 yhcA V ABC transporter, ATP-binding protein
KLHPDMAG_01747 1.3e-117 devA 3.6.3.25 V ABC transporter, ATP-binding protein
KLHPDMAG_01748 3.3e-168 hrtB V ABC transporter permease
KLHPDMAG_01749 4.1e-84 ygfC K transcriptional regulator (TetR family)
KLHPDMAG_01750 1.4e-189 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
KLHPDMAG_01751 1.2e-286 mntH P H( )-stimulated, divalent metal cation uptake system
KLHPDMAG_01752 1.7e-29
KLHPDMAG_01753 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KLHPDMAG_01755 5.8e-217 yxiO S Vacuole effluxer Atg22 like
KLHPDMAG_01756 1.1e-101 npp S type I phosphodiesterase nucleotide pyrophosphatase
KLHPDMAG_01757 1.1e-58 npp S type I phosphodiesterase nucleotide pyrophosphatase
KLHPDMAG_01758 1e-238 E amino acid
KLHPDMAG_01759 3e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KLHPDMAG_01760 1.2e-216 yxjG_1 E methionine synthase, vitamin-B12 independent
KLHPDMAG_01761 3.7e-35 S Cytochrome B5
KLHPDMAG_01762 1.4e-47 elaA S Gnat family
KLHPDMAG_01764 1.2e-120 GM NmrA-like family
KLHPDMAG_01765 1.8e-50 hxlR K Transcriptional regulator, HxlR family
KLHPDMAG_01766 4.1e-107 XK27_02070 S Nitroreductase family
KLHPDMAG_01767 1.5e-82 K Transcriptional regulator, HxlR family
KLHPDMAG_01768 2e-231
KLHPDMAG_01769 6.5e-210 EGP Major facilitator Superfamily
KLHPDMAG_01770 4.4e-255 pepC 3.4.22.40 E aminopeptidase
KLHPDMAG_01771 9.9e-112 ylbE GM NAD dependent epimerase dehydratase family protein
KLHPDMAG_01772 0.0 pepN 3.4.11.2 E aminopeptidase
KLHPDMAG_01773 1.6e-47 K Transcriptional regulator
KLHPDMAG_01774 1.9e-40 folT S ECF transporter, substrate-specific component
KLHPDMAG_01775 6.8e-17 folT S ECF transporter, substrate-specific component
KLHPDMAG_01776 1.9e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
KLHPDMAG_01777 2.7e-257 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
KLHPDMAG_01778 5e-117 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
KLHPDMAG_01779 1.6e-85 2.7.7.65 T GGDEF domain
KLHPDMAG_01780 3.2e-80 L transposase and inactivated derivatives, IS30 family
KLHPDMAG_01781 2.2e-309 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KLHPDMAG_01782 0.0 M NlpC/P60 family
KLHPDMAG_01783 0.0 S Peptidase, M23
KLHPDMAG_01784 2.1e-35
KLHPDMAG_01785 2e-29 S Protein of unknown function (DUF2929)
KLHPDMAG_01786 0.0 dnaE 2.7.7.7 L DNA polymerase
KLHPDMAG_01787 1.4e-270 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KLHPDMAG_01788 1.3e-57
KLHPDMAG_01789 6.6e-125 phoU P Plays a role in the regulation of phosphate uptake
KLHPDMAG_01790 3.1e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KLHPDMAG_01791 4.5e-155 pstA P Phosphate transport system permease protein PstA
KLHPDMAG_01792 1.1e-153 pstC P probably responsible for the translocation of the substrate across the membrane
KLHPDMAG_01793 8.6e-159 pstS P Phosphate
KLHPDMAG_01794 1.7e-133 K Transcriptional regulatory protein, C-terminal domain protein
KLHPDMAG_01795 2.1e-80 GM domain, Protein
KLHPDMAG_01796 4.1e-98 yslB S Protein of unknown function (DUF2507)
KLHPDMAG_01797 1.1e-147 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KLHPDMAG_01798 3.4e-106 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KLHPDMAG_01799 3.4e-94 S Phosphoesterase
KLHPDMAG_01800 1.1e-74 ykuL S (CBS) domain
KLHPDMAG_01801 1.4e-153 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
KLHPDMAG_01802 3.4e-147 ykuT M mechanosensitive ion channel
KLHPDMAG_01803 9.8e-34 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KLHPDMAG_01804 1.5e-29
KLHPDMAG_01805 3e-67 L Belongs to the 'phage' integrase family
KLHPDMAG_01806 2.4e-115 M Lysin motif
KLHPDMAG_01807 2.1e-79
KLHPDMAG_01808 3.1e-28 wecD3 K PFAM GCN5-related N-acetyltransferase
KLHPDMAG_01809 7e-56 wecD3 K PFAM GCN5-related N-acetyltransferase
KLHPDMAG_01810 7.7e-96 ltrA S Bacterial low temperature requirement A protein (LtrA)
KLHPDMAG_01811 2.8e-205 cytX U Belongs to the purine-cytosine permease (2.A.39) family
KLHPDMAG_01812 4.3e-13
KLHPDMAG_01813 7.1e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KLHPDMAG_01814 8.3e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KLHPDMAG_01815 4.4e-190 yeaN P Transporter, major facilitator family protein
KLHPDMAG_01816 2.7e-73 S 3-demethylubiquinone-9 3-methyltransferase
KLHPDMAG_01817 2.6e-41
KLHPDMAG_01818 3.7e-62
KLHPDMAG_01819 2.9e-36
KLHPDMAG_01820 4.7e-207 potD P ABC transporter
KLHPDMAG_01821 1.9e-139 potC P ABC transporter permease
KLHPDMAG_01822 1.3e-145 potB P ABC transporter permease
KLHPDMAG_01823 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KLHPDMAG_01824 1.8e-209 fhaB M Rib/alpha-like repeat
KLHPDMAG_01825 2.7e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KLHPDMAG_01826 7.9e-167
KLHPDMAG_01827 3e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KLHPDMAG_01828 1.4e-242 purD 6.3.4.13 F Belongs to the GARS family
KLHPDMAG_01829 4.6e-296 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KLHPDMAG_01830 8e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KLHPDMAG_01831 6.2e-196 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KLHPDMAG_01832 2.9e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KLHPDMAG_01833 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KLHPDMAG_01834 3.6e-128 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KLHPDMAG_01835 4.1e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KLHPDMAG_01836 4.8e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KLHPDMAG_01837 8.9e-253 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KLHPDMAG_01838 3.9e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KLHPDMAG_01839 1.1e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KLHPDMAG_01840 3.6e-101 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KLHPDMAG_01841 5.8e-172 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
KLHPDMAG_01842 4.9e-186 thrC 4.2.3.1 E Threonine synthase
KLHPDMAG_01843 4.5e-24 K helix_turn_helix, arabinose operon control protein
KLHPDMAG_01844 4.5e-129 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
KLHPDMAG_01845 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KLHPDMAG_01846 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
KLHPDMAG_01847 3.3e-173 K AI-2E family transporter
KLHPDMAG_01848 3.1e-228 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
KLHPDMAG_01849 1e-95 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KLHPDMAG_01850 1.1e-113 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
KLHPDMAG_01851 9.6e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KLHPDMAG_01852 6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KLHPDMAG_01853 7.2e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KLHPDMAG_01854 7.3e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KLHPDMAG_01855 5e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KLHPDMAG_01856 8.6e-98 K LysR substrate binding domain
KLHPDMAG_01857 1.1e-24 K LysR substrate binding domain
KLHPDMAG_01858 1.6e-52 azlD S branched-chain amino acid
KLHPDMAG_01859 2.3e-138 azlC E AzlC protein
KLHPDMAG_01860 2.4e-201 hpk31 2.7.13.3 T Histidine kinase
KLHPDMAG_01861 3.8e-125 K response regulator
KLHPDMAG_01862 1.6e-208 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KLHPDMAG_01863 1.4e-170 deoR K sugar-binding domain protein
KLHPDMAG_01864 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
KLHPDMAG_01865 3.2e-234 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
KLHPDMAG_01866 4.5e-235 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
KLHPDMAG_01867 3.4e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KLHPDMAG_01868 3.1e-136 XK27_01040 S Protein of unknown function (DUF1129)
KLHPDMAG_01869 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KLHPDMAG_01870 1.2e-31 yyzM S Bacterial protein of unknown function (DUF951)
KLHPDMAG_01871 4.2e-153 spo0J K Belongs to the ParB family
KLHPDMAG_01872 1e-139 soj D Sporulation initiation inhibitor
KLHPDMAG_01873 8.7e-144 noc K Belongs to the ParB family
KLHPDMAG_01874 1.7e-123 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
KLHPDMAG_01875 1.1e-161 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
KLHPDMAG_01876 1.7e-170 rihC 3.2.2.1 F Nucleoside
KLHPDMAG_01877 1.3e-218 nupG F Nucleoside transporter
KLHPDMAG_01878 4.7e-220 cycA E Amino acid permease
KLHPDMAG_01879 5.5e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KLHPDMAG_01880 2e-264 glnP P ABC transporter
KLHPDMAG_01881 1.9e-250 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KLHPDMAG_01882 4.1e-36 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
KLHPDMAG_01883 1.5e-26 L PFAM transposase IS200-family protein
KLHPDMAG_01884 2.2e-176 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KLHPDMAG_01885 5.9e-201 XK27_09615 S reductase
KLHPDMAG_01886 2.7e-100 nqr 1.5.1.36 S reductase
KLHPDMAG_01887 3.8e-265 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KLHPDMAG_01888 1.3e-174 K Transcriptional regulator, LacI family
KLHPDMAG_01889 2.3e-259 G Major Facilitator
KLHPDMAG_01890 8.1e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KLHPDMAG_01891 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
KLHPDMAG_01892 2.8e-57 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
KLHPDMAG_01893 1.8e-196 EGP Major facilitator Superfamily
KLHPDMAG_01894 1e-37 D Antitoxin component of a toxin-antitoxin (TA) module
KLHPDMAG_01895 4.6e-49 S ParE toxin of type II toxin-antitoxin system, parDE
KLHPDMAG_01896 8.8e-88 ywlG S Belongs to the UPF0340 family
KLHPDMAG_01897 2.3e-159 spoU 2.1.1.185 J Methyltransferase
KLHPDMAG_01898 5e-89 yeeA V Type II restriction enzyme, methylase subunits
KLHPDMAG_01899 4.9e-20
KLHPDMAG_01901 3.3e-87 L Belongs to the 'phage' integrase family
KLHPDMAG_01902 3.6e-103 L Integrase core domain
KLHPDMAG_01904 1.1e-158 metQ_4 P Belongs to the nlpA lipoprotein family
KLHPDMAG_01905 2.6e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KLHPDMAG_01906 5.1e-122 O Zinc-dependent metalloprotease
KLHPDMAG_01907 1.4e-33 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
KLHPDMAG_01908 6.1e-57
KLHPDMAG_01909 0.0 lacS G Transporter
KLHPDMAG_01910 2.3e-28
KLHPDMAG_01911 1.1e-84 S Short repeat of unknown function (DUF308)
KLHPDMAG_01912 2.2e-78 S Psort location Cytoplasmic, score
KLHPDMAG_01913 1.2e-285 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
KLHPDMAG_01914 1.5e-129 yfnA E Amino Acid
KLHPDMAG_01915 2.3e-177 S FRG
KLHPDMAG_01916 0.0 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KLHPDMAG_01917 3.9e-68 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
KLHPDMAG_01918 5.5e-45 yitW S Pfam:DUF59
KLHPDMAG_01919 1.6e-169 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KLHPDMAG_01920 2.9e-19 S PFAM Archaeal ATPase
KLHPDMAG_01921 5.9e-73 S ECF transporter, substrate-specific component
KLHPDMAG_01922 9.8e-51 S Domain of unknown function (DUF4430)
KLHPDMAG_01923 8.1e-18 cnrT EG PFAM EamA-like transporter family
KLHPDMAG_01924 8.6e-20 cnrT EG PFAM EamA-like transporter family
KLHPDMAG_01925 2.9e-11
KLHPDMAG_01927 6.5e-243 ydaM M Glycosyl transferase
KLHPDMAG_01928 1.1e-222 G Glycosyl hydrolases family 8
KLHPDMAG_01929 2.7e-140 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
KLHPDMAG_01930 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
KLHPDMAG_01931 3.8e-238 ktrB P Potassium uptake protein
KLHPDMAG_01932 2e-115 ktrA P domain protein
KLHPDMAG_01933 1.9e-79 Q Methyltransferase
KLHPDMAG_01934 6.3e-230 mntH P H( )-stimulated, divalent metal cation uptake system
KLHPDMAG_01935 1.5e-177 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KLHPDMAG_01936 6.1e-171 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KLHPDMAG_01937 1.2e-94 S NADPH-dependent FMN reductase
KLHPDMAG_01938 4e-179 MA20_14895 S Conserved hypothetical protein 698
KLHPDMAG_01939 3e-133 I alpha/beta hydrolase fold
KLHPDMAG_01940 5.3e-159 lsa S ABC transporter
KLHPDMAG_01941 5.2e-101 lsa S ABC transporter
KLHPDMAG_01942 3e-181 yfeX P Peroxidase
KLHPDMAG_01943 5.3e-273 arcD S C4-dicarboxylate anaerobic carrier
KLHPDMAG_01944 4.3e-258 ytjP 3.5.1.18 E Dipeptidase
KLHPDMAG_01945 3.7e-216 uhpT EGP Major facilitator Superfamily
KLHPDMAG_01946 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
KLHPDMAG_01947 2.6e-130 ponA V Beta-lactamase enzyme family
KLHPDMAG_01948 8.7e-229 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KLHPDMAG_01949 3e-75
KLHPDMAG_01950 5.4e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
KLHPDMAG_01951 2.2e-21
KLHPDMAG_01952 5.1e-262 S Uncharacterized protein conserved in bacteria (DUF2252)
KLHPDMAG_01953 2e-160 L transposase, IS605 OrfB family
KLHPDMAG_01954 1e-295 L PFAM plasmid pRiA4b ORF-3 family protein
KLHPDMAG_01955 1.9e-205 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
KLHPDMAG_01956 6.6e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KLHPDMAG_01957 1.3e-157 mleR K LysR family
KLHPDMAG_01958 2.2e-304 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
KLHPDMAG_01959 4e-259 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KLHPDMAG_01960 5.8e-266 frdC 1.3.5.4 C FAD binding domain
KLHPDMAG_01961 4.9e-252 yflS P Sodium:sulfate symporter transmembrane region
KLHPDMAG_01962 3.9e-159 mleR K LysR family
KLHPDMAG_01963 9.4e-253 yjjP S Putative threonine/serine exporter
KLHPDMAG_01964 1e-116 ung2 3.2.2.27 L Uracil-DNA glycosylase
KLHPDMAG_01965 3.2e-270 emrY EGP Major facilitator Superfamily
KLHPDMAG_01966 2.5e-186 I Alpha beta
KLHPDMAG_01967 9.8e-103 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
KLHPDMAG_01968 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KLHPDMAG_01970 8.9e-164 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
KLHPDMAG_01971 1.9e-122 S Domain of unknown function (DUF4811)
KLHPDMAG_01972 2.1e-269 lmrB EGP Major facilitator Superfamily
KLHPDMAG_01973 3.1e-72 merR K MerR HTH family regulatory protein
KLHPDMAG_01974 2.9e-57
KLHPDMAG_01975 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KLHPDMAG_01976 8.3e-221 S CAAX protease self-immunity
KLHPDMAG_01977 3.6e-109 glnP P ABC transporter permease
KLHPDMAG_01978 2.4e-110 gluC P ABC transporter permease
KLHPDMAG_01979 7.5e-152 glnH ET ABC transporter
KLHPDMAG_01980 3.1e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KLHPDMAG_01981 5.5e-83 usp1 T Belongs to the universal stress protein A family
KLHPDMAG_01982 1.9e-108 S VIT family
KLHPDMAG_01983 4.2e-116 S membrane
KLHPDMAG_01984 3.2e-164 czcD P cation diffusion facilitator family transporter
KLHPDMAG_01985 7.7e-123 sirR K iron dependent repressor
KLHPDMAG_01986 1e-30 cspC K Cold shock protein
KLHPDMAG_01987 2.6e-127 thrE S Putative threonine/serine exporter
KLHPDMAG_01988 1e-81 S Threonine/Serine exporter, ThrE
KLHPDMAG_01989 6.8e-119 lssY 3.6.1.27 I phosphatase
KLHPDMAG_01990 4.7e-08 2.3.1.128 J Acetyltransferase (GNAT) domain
KLHPDMAG_01991 4.3e-275 lysP E amino acid
KLHPDMAG_01992 5.6e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
KLHPDMAG_01998 2.6e-150 L hmm pf00665
KLHPDMAG_01999 2.8e-55 L Helix-turn-helix domain
KLHPDMAG_02000 2.7e-43 L Helix-turn-helix domain
KLHPDMAG_02001 5.8e-132 O Bacterial dnaA protein
KLHPDMAG_02002 1.6e-238 L Integrase core domain
KLHPDMAG_02003 0.0 FbpA K Fibronectin-binding protein
KLHPDMAG_02004 1.2e-230 L Integrase core domain
KLHPDMAG_02005 1.2e-235 L transposase IS116 IS110 IS902 family protein
KLHPDMAG_02006 2.2e-229 L transposase, IS605 OrfB family
KLHPDMAG_02007 5.6e-261 S Uncharacterised protein family (UPF0236)
KLHPDMAG_02008 9.9e-71 L Helix-turn-helix domain
KLHPDMAG_02009 3.5e-34 M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KLHPDMAG_02010 9.3e-169 cvfB S S1 domain
KLHPDMAG_02011 1.3e-162 xerD D recombinase XerD
KLHPDMAG_02012 2.8e-63 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KLHPDMAG_02013 2.5e-136 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KLHPDMAG_02014 1.7e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KLHPDMAG_02015 5.9e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KLHPDMAG_02016 1.6e-70 L Belongs to the 'phage' integrase family
KLHPDMAG_02017 1.5e-33 ligA 2.7.7.7, 6.5.1.2 L EXOIII
KLHPDMAG_02018 5.2e-75 E IrrE N-terminal-like domain
KLHPDMAG_02019 1.6e-49 K Cro/C1-type HTH DNA-binding domain
KLHPDMAG_02020 1.3e-15 K Helix-turn-helix XRE-family like proteins
KLHPDMAG_02022 2.5e-69 S Protein of unknown function (DUF3102)
KLHPDMAG_02029 3.8e-07
KLHPDMAG_02031 3.8e-58 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KLHPDMAG_02032 1.9e-129 S Putative HNHc nuclease
KLHPDMAG_02033 1.6e-139 L Psort location Cytoplasmic, score
KLHPDMAG_02037 4.5e-23
KLHPDMAG_02038 4.3e-35
KLHPDMAG_02039 1.6e-76 rusA L Endodeoxyribonuclease RusA
KLHPDMAG_02048 3.3e-80 Q DNA (cytosine-5-)-methyltransferase activity
KLHPDMAG_02052 1.1e-133
KLHPDMAG_02058 1.5e-129 dck 2.7.1.74 F deoxynucleoside kinase
KLHPDMAG_02062 1.9e-74 S Transcriptional regulator, RinA family
KLHPDMAG_02064 0.0
KLHPDMAG_02065 2.6e-207 XK27_11280 S Psort location CytoplasmicMembrane, score
KLHPDMAG_02076 1.7e-35 L NUMOD4 motif
KLHPDMAG_02077 6.1e-105 pnuC H nicotinamide mononucleotide transporter
KLHPDMAG_02079 1.4e-37
KLHPDMAG_02093 4.2e-53 L HNH nucleases
KLHPDMAG_02094 1e-78 L Phage terminase, small subunit
KLHPDMAG_02095 3e-267 S Phage Terminase
KLHPDMAG_02097 6.2e-148 S portal protein
KLHPDMAG_02098 1.3e-83 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
KLHPDMAG_02099 2.6e-139 S Phage capsid family
KLHPDMAG_02100 3.1e-43 S Phage gp6-like head-tail connector protein
KLHPDMAG_02101 2.4e-38 S Phage head-tail joining protein
KLHPDMAG_02102 3.3e-21
KLHPDMAG_02103 7.5e-25
KLHPDMAG_02104 7.4e-68 S Phage tail tube protein
KLHPDMAG_02105 6.2e-19
KLHPDMAG_02106 0.0 M Phage tail tape measure protein TP901
KLHPDMAG_02107 1.9e-142 S Phage tail protein
KLHPDMAG_02108 1.6e-290 M Prophage endopeptidase tail
KLHPDMAG_02109 4.3e-36
KLHPDMAG_02110 4.6e-65 3.4.24.40 M Peptidase family M23
KLHPDMAG_02112 9.6e-115 cotH M CotH kinase protein
KLHPDMAG_02115 7.7e-14
KLHPDMAG_02116 8.8e-54 S Bacteriophage holin of superfamily 6 (Holin_LLH)
KLHPDMAG_02117 3.9e-237 L Transposase
KLHPDMAG_02127 2.6e-61 XK27_01125 L PFAM IS66 Orf2 family protein
KLHPDMAG_02137 4.2e-98 L Transposase IS66 family
KLHPDMAG_02138 6.2e-17
KLHPDMAG_02142 1.7e-263 dtpT U amino acid peptide transporter
KLHPDMAG_02143 5.9e-149 yjjH S Calcineurin-like phosphoesterase
KLHPDMAG_02146 8.5e-111
KLHPDMAG_02147 8.5e-249 EGP Major facilitator Superfamily
KLHPDMAG_02148 3.5e-302 aspT P Predicted Permease Membrane Region
KLHPDMAG_02149 8.2e-131 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
KLHPDMAG_02150 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
KLHPDMAG_02151 3.1e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KLHPDMAG_02152 5.7e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KLHPDMAG_02153 0.0 yhgF K Tex-like protein N-terminal domain protein
KLHPDMAG_02154 6.2e-84 ydcK S Belongs to the SprT family
KLHPDMAG_02156 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
KLHPDMAG_02157 1.5e-183 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
KLHPDMAG_02158 0.0 S Bacterial membrane protein, YfhO
KLHPDMAG_02159 1e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KLHPDMAG_02160 4.5e-168 I alpha/beta hydrolase fold
KLHPDMAG_02161 3.2e-214 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KLHPDMAG_02162 1.4e-119 tcyB E ABC transporter
KLHPDMAG_02163 9.8e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KLHPDMAG_02164 2.4e-139 tcyA ET Belongs to the bacterial solute-binding protein 3 family
KLHPDMAG_02165 7.3e-266 pepC 3.4.22.40 E Peptidase C1-like family
KLHPDMAG_02166 2.2e-125 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KLHPDMAG_02167 1.9e-49 HA62_12640 S GCN5-related N-acetyl-transferase
KLHPDMAG_02168 2.3e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
KLHPDMAG_02169 8.6e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KLHPDMAG_02170 3.1e-204 yacL S domain protein
KLHPDMAG_02171 3.9e-270 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KLHPDMAG_02172 1.4e-69 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KLHPDMAG_02173 4.7e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KLHPDMAG_02174 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KLHPDMAG_02175 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KLHPDMAG_02176 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
KLHPDMAG_02177 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KLHPDMAG_02178 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KLHPDMAG_02179 8e-224 aadAT EK Aminotransferase, class I
KLHPDMAG_02181 1.2e-74 M Glycosyl transferase family group 2
KLHPDMAG_02182 5.7e-138 M Glycosyl transferase family group 2
KLHPDMAG_02183 9.9e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KLHPDMAG_02184 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KLHPDMAG_02185 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KLHPDMAG_02186 3.4e-48
KLHPDMAG_02187 3.2e-38 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KLHPDMAG_02188 8.9e-56 K transcriptional regulator PadR family
KLHPDMAG_02189 2.1e-79 XK27_06920 S Protein of unknown function (DUF1700)
KLHPDMAG_02190 1.9e-133 S Putative adhesin
KLHPDMAG_02191 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KLHPDMAG_02192 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KLHPDMAG_02193 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KLHPDMAG_02194 3.4e-35 nrdH O Glutaredoxin
KLHPDMAG_02195 2.3e-87 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KLHPDMAG_02196 6.2e-292 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KLHPDMAG_02197 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KLHPDMAG_02198 6.3e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KLHPDMAG_02199 2.8e-38 S Protein of unknown function (DUF2508)
KLHPDMAG_02200 2.9e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KLHPDMAG_02201 2.9e-51 yaaQ S Cyclic-di-AMP receptor
KLHPDMAG_02202 1.3e-182 holB 2.7.7.7 L DNA polymerase III
KLHPDMAG_02203 3.1e-43 yabA L Involved in initiation control of chromosome replication
KLHPDMAG_02204 6.4e-154 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KLHPDMAG_02205 1.6e-132 fat 3.1.2.21 I Acyl-ACP thioesterase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)