ORF_ID e_value Gene_name EC_number CAZy COGs Description
JGNPNPGP_00001 2.8e-131 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JGNPNPGP_00002 1.3e-201 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
JGNPNPGP_00003 1.3e-117 J 2'-5' RNA ligase superfamily
JGNPNPGP_00004 2.2e-70 yqhY S Asp23 family, cell envelope-related function
JGNPNPGP_00005 1.2e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JGNPNPGP_00006 8e-149 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JGNPNPGP_00007 1.3e-235 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
JGNPNPGP_00008 1.5e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
JGNPNPGP_00009 3.2e-153 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
JGNPNPGP_00010 1.5e-149 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
JGNPNPGP_00011 1.1e-77 argR K Regulates arginine biosynthesis genes
JGNPNPGP_00012 1.5e-260 recN L May be involved in recombinational repair of damaged DNA
JGNPNPGP_00013 1.7e-54
JGNPNPGP_00014 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
JGNPNPGP_00015 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
JGNPNPGP_00016 1.1e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JGNPNPGP_00017 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JGNPNPGP_00018 9.4e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JGNPNPGP_00019 2.1e-249 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JGNPNPGP_00020 5.9e-132 stp 3.1.3.16 T phosphatase
JGNPNPGP_00021 0.0 KLT serine threonine protein kinase
JGNPNPGP_00022 7.7e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
JGNPNPGP_00023 1.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
JGNPNPGP_00024 4.1e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
JGNPNPGP_00025 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
JGNPNPGP_00026 4.7e-58 asp S Asp23 family, cell envelope-related function
JGNPNPGP_00027 0.0 yloV S DAK2 domain fusion protein YloV
JGNPNPGP_00028 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JGNPNPGP_00029 1.5e-186 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
JGNPNPGP_00030 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
JGNPNPGP_00031 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
JGNPNPGP_00032 0.0 smc D Required for chromosome condensation and partitioning
JGNPNPGP_00033 3.3e-177 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
JGNPNPGP_00034 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JGNPNPGP_00035 1.3e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JGNPNPGP_00036 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
JGNPNPGP_00037 1.6e-39 ylqC S Belongs to the UPF0109 family
JGNPNPGP_00038 2e-91 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JGNPNPGP_00039 2.2e-142 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
JGNPNPGP_00040 6.8e-262 yfnA E amino acid
JGNPNPGP_00041 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
JGNPNPGP_00042 7.7e-35
JGNPNPGP_00043 7.1e-53 S Mazg nucleotide pyrophosphohydrolase
JGNPNPGP_00044 1.4e-158 xth 3.1.11.2 L exodeoxyribonuclease III
JGNPNPGP_00045 1.5e-83
JGNPNPGP_00046 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
JGNPNPGP_00047 1.3e-112 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JGNPNPGP_00048 1.3e-37 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JGNPNPGP_00049 3.5e-51 S CRISPR-associated protein (Cas_Csn2)
JGNPNPGP_00050 6.7e-187 lacR K Transcriptional regulator
JGNPNPGP_00051 0.0 lacS G Transporter
JGNPNPGP_00052 0.0 lacZ 3.2.1.23 G -beta-galactosidase
JGNPNPGP_00053 6.5e-179 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
JGNPNPGP_00054 2.6e-158 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
JGNPNPGP_00055 3.9e-144 XK27_00940 1.2.1.70, 3.5.1.9 S Putative cyclase
JGNPNPGP_00056 1.6e-221 yxjG_1 E methionine synthase, vitamin-B12 independent
JGNPNPGP_00057 3e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
JGNPNPGP_00058 8.2e-224 mdtG EGP Major facilitator Superfamily
JGNPNPGP_00059 6.4e-167 T Calcineurin-like phosphoesterase superfamily domain
JGNPNPGP_00060 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JGNPNPGP_00062 6.4e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
JGNPNPGP_00063 3.3e-142 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
JGNPNPGP_00064 1.2e-105 ahpC 1.11.1.15 O Peroxiredoxin
JGNPNPGP_00065 0.0 trxB2 1.8.1.9 C Thioredoxin domain
JGNPNPGP_00066 0.0 M LPXTG-motif cell wall anchor domain protein
JGNPNPGP_00069 1.4e-68 infB UW LPXTG-motif cell wall anchor domain protein
JGNPNPGP_00070 1.2e-181 S Phosphotransferase system, EIIC
JGNPNPGP_00071 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JGNPNPGP_00072 1.7e-180
JGNPNPGP_00073 2.5e-64 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JGNPNPGP_00074 1.3e-207 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
JGNPNPGP_00075 9.5e-161 K LysR substrate binding domain
JGNPNPGP_00076 4.3e-143 manA 5.3.1.8 G mannose-6-phosphate isomerase
JGNPNPGP_00077 4.4e-97 2.3.1.128 K acetyltransferase
JGNPNPGP_00078 7.3e-186
JGNPNPGP_00079 3.3e-17 K Transcriptional regulator, HxlR family
JGNPNPGP_00080 1.1e-223 P ammonium transporter
JGNPNPGP_00081 5.6e-97 ureI S AmiS/UreI family transporter
JGNPNPGP_00082 8.2e-48 ureA 3.5.1.5 E Urease, gamma subunit
JGNPNPGP_00083 2.1e-69 ureB 3.5.1.5 E Urease beta subunit
JGNPNPGP_00084 0.0 ureC 3.5.1.5 E Amidohydrolase family
JGNPNPGP_00085 8.6e-78 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
JGNPNPGP_00086 1.9e-132 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
JGNPNPGP_00087 3.6e-114 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
JGNPNPGP_00088 3.2e-166 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
JGNPNPGP_00089 3.7e-185 nikMN P PDGLE domain
JGNPNPGP_00090 3.8e-135 P Cobalt transport protein
JGNPNPGP_00091 8.6e-136 cbiO P ABC transporter
JGNPNPGP_00092 2.3e-133 K Transcriptional regulatory protein, C-terminal domain protein
JGNPNPGP_00093 5.6e-158 pstS P Phosphate
JGNPNPGP_00094 9.5e-153 pstC P probably responsible for the translocation of the substrate across the membrane
JGNPNPGP_00095 6.5e-154 pstA P Phosphate transport system permease protein PstA
JGNPNPGP_00096 1.1e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JGNPNPGP_00097 6.6e-125 phoU P Plays a role in the regulation of phosphate uptake
JGNPNPGP_00098 1.1e-134
JGNPNPGP_00100 1.9e-242 ydaM M Glycosyl transferase
JGNPNPGP_00101 2e-219 G Glycosyl hydrolases family 8
JGNPNPGP_00102 4.8e-137 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
JGNPNPGP_00103 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
JGNPNPGP_00104 4.5e-239 ktrB P Potassium uptake protein
JGNPNPGP_00105 1.4e-116 ktrA P domain protein
JGNPNPGP_00106 3e-77 Q Methyltransferase
JGNPNPGP_00107 1.2e-06 S Domain of unknown function (DUF4767)
JGNPNPGP_00109 3.7e-12
JGNPNPGP_00112 3.8e-06 D nuclear chromosome segregation
JGNPNPGP_00114 1.4e-54 T GHKL domain
JGNPNPGP_00115 2e-63 agrA K LytTr DNA-binding domain
JGNPNPGP_00116 8.8e-232 mntH P H( )-stimulated, divalent metal cation uptake system
JGNPNPGP_00117 1.2e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
JGNPNPGP_00118 1.3e-168 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
JGNPNPGP_00119 1.4e-95 S NADPH-dependent FMN reductase
JGNPNPGP_00120 1.6e-180 MA20_14895 S Conserved hypothetical protein 698
JGNPNPGP_00121 5.9e-137 I alpha/beta hydrolase fold
JGNPNPGP_00122 6.3e-170 lsa S ABC transporter
JGNPNPGP_00123 5.1e-181 yfeX P Peroxidase
JGNPNPGP_00124 7.5e-275 arcD S C4-dicarboxylate anaerobic carrier
JGNPNPGP_00125 1.1e-258 ytjP 3.5.1.18 E Dipeptidase
JGNPNPGP_00126 1e-213 uhpT EGP Major facilitator Superfamily
JGNPNPGP_00127 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
JGNPNPGP_00128 1.9e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JGNPNPGP_00129 4.2e-152
JGNPNPGP_00130 5.1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JGNPNPGP_00131 9e-242 purD 6.3.4.13 F Belongs to the GARS family
JGNPNPGP_00132 5.9e-296 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
JGNPNPGP_00133 5e-102 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JGNPNPGP_00134 2e-194 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
JGNPNPGP_00135 2e-277 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JGNPNPGP_00136 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JGNPNPGP_00137 3.6e-128 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JGNPNPGP_00138 1.8e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JGNPNPGP_00139 2.4e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
JGNPNPGP_00140 4e-253 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JGNPNPGP_00141 1.1e-214 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JGNPNPGP_00142 1.1e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JGNPNPGP_00143 1.3e-131 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
JGNPNPGP_00144 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
JGNPNPGP_00145 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
JGNPNPGP_00146 6.2e-172 K AI-2E family transporter
JGNPNPGP_00147 7.4e-230 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
JGNPNPGP_00148 5.3e-113 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
JGNPNPGP_00149 3.7e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JGNPNPGP_00150 6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
JGNPNPGP_00151 7.2e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
JGNPNPGP_00152 9.6e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
JGNPNPGP_00153 2.5e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
JGNPNPGP_00154 3e-135 K LysR substrate binding domain
JGNPNPGP_00155 3.6e-52 azlD S branched-chain amino acid
JGNPNPGP_00156 2.7e-139 azlC E AzlC protein
JGNPNPGP_00157 1.7e-202 hpk31 2.7.13.3 T Histidine kinase
JGNPNPGP_00158 3.8e-125 K response regulator
JGNPNPGP_00159 4.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
JGNPNPGP_00160 1.3e-171 deoR K sugar-binding domain protein
JGNPNPGP_00161 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
JGNPNPGP_00162 1e-235 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
JGNPNPGP_00163 7e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
JGNPNPGP_00164 3.4e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JGNPNPGP_00165 3.1e-136 XK27_01040 S Protein of unknown function (DUF1129)
JGNPNPGP_00166 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
JGNPNPGP_00167 5.4e-32 yyzM S Bacterial protein of unknown function (DUF951)
JGNPNPGP_00168 1.6e-152 spo0J K Belongs to the ParB family
JGNPNPGP_00169 3.9e-139 soj D Sporulation initiation inhibitor
JGNPNPGP_00170 7.6e-148 noc K Belongs to the ParB family
JGNPNPGP_00171 3.8e-128 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
JGNPNPGP_00172 2.2e-162 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
JGNPNPGP_00173 7.9e-171 rihC 3.2.2.1 F Nucleoside
JGNPNPGP_00174 1e-218 nupG F Nucleoside transporter
JGNPNPGP_00175 1.1e-221 cycA E Amino acid permease
JGNPNPGP_00176 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
JGNPNPGP_00177 3e-265 glnP P ABC transporter
JGNPNPGP_00178 2.1e-249 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JGNPNPGP_00179 3.7e-87 UW LPXTG-motif cell wall anchor domain protein
JGNPNPGP_00180 0.0 UW LPXTG-motif cell wall anchor domain protein
JGNPNPGP_00181 0.0 UW LPXTG-motif cell wall anchor domain protein
JGNPNPGP_00183 4e-156 metQ_4 P Belongs to the nlpA lipoprotein family
JGNPNPGP_00184 7.4e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
JGNPNPGP_00185 7.6e-126 O Zinc-dependent metalloprotease
JGNPNPGP_00186 1.9e-115 S Membrane
JGNPNPGP_00187 2.5e-197 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
JGNPNPGP_00188 3.1e-77 S Domain of unknown function (DUF4767)
JGNPNPGP_00189 4.3e-13
JGNPNPGP_00190 3.9e-199 cytX U Belongs to the purine-cytosine permease (2.A.39) family
JGNPNPGP_00191 2.2e-98 ltrA S Bacterial low temperature requirement A protein (LtrA)
JGNPNPGP_00192 1.1e-78
JGNPNPGP_00193 1.9e-120 M Lysin motif
JGNPNPGP_00194 2.2e-194 EGP Major facilitator Superfamily
JGNPNPGP_00195 1e-37 D Antitoxin component of a toxin-antitoxin (TA) module
JGNPNPGP_00196 6.7e-48 S ParE toxin of type II toxin-antitoxin system, parDE
JGNPNPGP_00197 2.5e-98 ywlG S Belongs to the UPF0340 family
JGNPNPGP_00198 4.7e-100 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
JGNPNPGP_00199 8.1e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
JGNPNPGP_00200 2.4e-138 pnuC H nicotinamide mononucleotide transporter
JGNPNPGP_00201 9.6e-127 udp 2.4.2.1, 2.4.2.3 F Phosphorylase superfamily
JGNPNPGP_00202 2e-99 crp_2 K Cyclic nucleotide-binding domain
JGNPNPGP_00203 1.4e-126 S PFAM Archaeal ATPase
JGNPNPGP_00204 1.8e-169 cscA 3.2.1.26 GH32 G Glycosyl hydrolases family 32
JGNPNPGP_00205 1.3e-163 cscB G LacY proton/sugar symporter
JGNPNPGP_00206 5.9e-55 L PFAM Integrase catalytic region
JGNPNPGP_00207 5e-32 L Helix-turn-helix domain
JGNPNPGP_00208 8.1e-11 G Major facilitator Superfamily
JGNPNPGP_00209 2e-257
JGNPNPGP_00210 5.9e-117 L PFAM Integrase catalytic region
JGNPNPGP_00211 9e-193 S PFAM Archaeal ATPase
JGNPNPGP_00212 4.8e-46
JGNPNPGP_00214 3.8e-87 3.6.4.12 S PD-(D/E)XK nuclease family transposase
JGNPNPGP_00215 8.8e-207 amtB P ammonium transporter
JGNPNPGP_00216 3.7e-246 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
JGNPNPGP_00217 1.5e-92 S B3 4 domain
JGNPNPGP_00218 3.1e-166 lmrB P Belongs to the major facilitator superfamily
JGNPNPGP_00219 2.2e-91
JGNPNPGP_00220 5.2e-124 pnb C nitroreductase
JGNPNPGP_00221 3.2e-171 XK27_00915 C Luciferase-like monooxygenase
JGNPNPGP_00222 1.6e-155 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
JGNPNPGP_00223 8e-68 S Protein of unknown function (DUF3021)
JGNPNPGP_00224 5.4e-77 K LytTr DNA-binding domain
JGNPNPGP_00225 1.3e-93 K Acetyltransferase (GNAT) family
JGNPNPGP_00226 3.1e-21
JGNPNPGP_00227 9.1e-204 yhjX P Major Facilitator Superfamily
JGNPNPGP_00228 2.2e-120 ybhL S Belongs to the BI1 family
JGNPNPGP_00229 2.1e-76 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
JGNPNPGP_00230 3.1e-192 S Protein of unknown function (DUF3114)
JGNPNPGP_00231 1.3e-295 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
JGNPNPGP_00232 1.7e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
JGNPNPGP_00233 6e-108 yvdD 3.2.2.10 S Belongs to the LOG family
JGNPNPGP_00234 9.1e-62 S Domain of unknown function (DUF4828)
JGNPNPGP_00235 1.3e-190 mocA S Oxidoreductase
JGNPNPGP_00236 5.7e-231 yfmL L DEAD DEAH box helicase
JGNPNPGP_00238 1.2e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
JGNPNPGP_00239 3e-21
JGNPNPGP_00240 2.3e-67 gtcA S Teichoic acid glycosylation protein
JGNPNPGP_00241 5.1e-78 fld C Flavodoxin
JGNPNPGP_00242 2.5e-166 map 3.4.11.18 E Methionine Aminopeptidase
JGNPNPGP_00243 6e-221 arcT 2.6.1.1 E Aminotransferase
JGNPNPGP_00244 7.8e-258 E Arginine ornithine antiporter
JGNPNPGP_00245 6.2e-282 yjeM E Amino Acid
JGNPNPGP_00246 4e-151 yihY S Belongs to the UPF0761 family
JGNPNPGP_00247 1.9e-33 S Protein of unknown function (DUF2922)
JGNPNPGP_00248 6.5e-31
JGNPNPGP_00249 1.4e-136 recX 2.4.1.337 GT4 S Regulatory protein RecX
JGNPNPGP_00250 3.9e-147 cps1D M Domain of unknown function (DUF4422)
JGNPNPGP_00251 5.9e-174 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
JGNPNPGP_00252 8.5e-119 rfbP 2.7.8.6 M Bacterial sugar transferase
JGNPNPGP_00253 1.3e-215 glf 5.4.99.9 M UDP-galactopyranose mutase
JGNPNPGP_00254 4.3e-240 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
JGNPNPGP_00255 3e-150 waaB GT4 M Glycosyl transferases group 1
JGNPNPGP_00256 3.7e-132 M transferase activity, transferring glycosyl groups
JGNPNPGP_00257 0.0 yjcE P Sodium proton antiporter
JGNPNPGP_00258 1.6e-52 yvlA
JGNPNPGP_00259 2.4e-113 P Cobalt transport protein
JGNPNPGP_00260 1.1e-253 cbiO1 S ABC transporter, ATP-binding protein
JGNPNPGP_00261 2.7e-97 S ABC-type cobalt transport system, permease component
JGNPNPGP_00262 1.3e-132 S membrane transporter protein
JGNPNPGP_00263 2.5e-138 IQ KR domain
JGNPNPGP_00264 9.5e-183 iunH2 3.2.2.1 F nucleoside hydrolase
JGNPNPGP_00265 3.7e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
JGNPNPGP_00266 6.2e-78 S Double zinc ribbon
JGNPNPGP_00267 2.5e-152 T GHKL domain
JGNPNPGP_00268 3.6e-97 agrA K LytTr DNA-binding domain
JGNPNPGP_00272 7.9e-23 S Domain of unknown function (DUF4767)
JGNPNPGP_00273 4.7e-131 3.6.4.12 S PD-(D/E)XK nuclease family transposase
JGNPNPGP_00275 7.4e-150 3.6.4.12 S PD-(D/E)XK nuclease family transposase
JGNPNPGP_00276 1.5e-115 gph 3.1.3.18 S HAD hydrolase, family IA, variant
JGNPNPGP_00277 2.8e-255 yagE E amino acid
JGNPNPGP_00278 9.9e-85 dps P Belongs to the Dps family
JGNPNPGP_00279 0.0 pacL 3.6.3.8 P P-type ATPase
JGNPNPGP_00280 2.3e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
JGNPNPGP_00281 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
JGNPNPGP_00282 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
JGNPNPGP_00283 4.5e-146 potB P ABC transporter permease
JGNPNPGP_00284 6.5e-140 potC P ABC transporter permease
JGNPNPGP_00285 1.2e-207 potD P ABC transporter
JGNPNPGP_00286 7.4e-231
JGNPNPGP_00287 2.2e-230 EGP Sugar (and other) transporter
JGNPNPGP_00288 1e-254 yfnA E Amino Acid
JGNPNPGP_00289 6.9e-74 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
JGNPNPGP_00290 1.3e-102 gmk2 2.7.4.8 F Guanylate kinase
JGNPNPGP_00291 1.6e-81 zur P Belongs to the Fur family
JGNPNPGP_00292 3.1e-17 3.2.1.14 GH18
JGNPNPGP_00293 5.8e-152
JGNPNPGP_00296 4.9e-14
JGNPNPGP_00297 1e-37
JGNPNPGP_00298 1.7e-103 Z012_02110 S Protein of unknown function (DUF3383)
JGNPNPGP_00299 3.7e-23
JGNPNPGP_00301 6.2e-49 Z012_02125
JGNPNPGP_00302 6.7e-30
JGNPNPGP_00303 1.2e-18
JGNPNPGP_00304 1e-120
JGNPNPGP_00305 1.3e-31 S Domain of unknown function (DUF4355)
JGNPNPGP_00307 5.6e-91
JGNPNPGP_00308 2.8e-183 S Phage portal protein, SPP1 Gp6-like
JGNPNPGP_00309 1.7e-190 S Terminase-like family
JGNPNPGP_00310 3e-76 xtmA L Terminase small subunit
JGNPNPGP_00311 1.2e-19
JGNPNPGP_00313 1.5e-11
JGNPNPGP_00316 4.1e-29 rusA L Endodeoxyribonuclease RusA
JGNPNPGP_00318 5.1e-21 S Mazg nucleotide pyrophosphohydrolase
JGNPNPGP_00319 2.8e-25
JGNPNPGP_00324 6.6e-81 Q DNA (cytosine-5-)-methyltransferase activity
JGNPNPGP_00325 1e-54 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
JGNPNPGP_00330 2.9e-52 dnaC 3.4.21.53 L IstB-like ATP binding protein
JGNPNPGP_00331 4e-57 S calcium ion binding
JGNPNPGP_00332 1.2e-43 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
JGNPNPGP_00333 2.4e-92 S Putative HNHc nuclease
JGNPNPGP_00334 5.3e-43 S ERF superfamily
JGNPNPGP_00335 6.9e-11 S Bacteriophage Mu Gam like protein
JGNPNPGP_00339 2.6e-07 K Helix-turn-helix XRE-family like proteins
JGNPNPGP_00342 7.2e-34 S Phage regulatory protein Rha (Phage_pRha)
JGNPNPGP_00343 2.2e-16 K Helix-turn-helix XRE-family like proteins
JGNPNPGP_00344 6.6e-35 K Cro/C1-type HTH DNA-binding domain
JGNPNPGP_00345 6.4e-41 E Zn peptidase
JGNPNPGP_00347 4.7e-46
JGNPNPGP_00348 1.7e-207 L Belongs to the 'phage' integrase family
JGNPNPGP_00349 9.8e-39 pspC KT positive regulation of macromolecule biosynthetic process
JGNPNPGP_00350 1.6e-94 K Transcriptional regulator (TetR family)
JGNPNPGP_00351 1.5e-220 V domain protein
JGNPNPGP_00352 1.6e-180 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JGNPNPGP_00354 2e-31 S Transglycosylase associated protein
JGNPNPGP_00355 1.4e-10
JGNPNPGP_00356 6.8e-229 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JGNPNPGP_00357 5e-127 3.1.3.73 G phosphoglycerate mutase
JGNPNPGP_00358 7.5e-115 dedA S SNARE associated Golgi protein
JGNPNPGP_00359 0.0 helD 3.6.4.12 L DNA helicase
JGNPNPGP_00360 2.7e-244 nox C NADH oxidase
JGNPNPGP_00361 4.5e-255 nox C NADH oxidase
JGNPNPGP_00362 7e-161 EG EamA-like transporter family
JGNPNPGP_00363 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
JGNPNPGP_00364 1.7e-176 coaA 2.7.1.33 F Pantothenic acid kinase
JGNPNPGP_00365 3.7e-221 S cog cog1373
JGNPNPGP_00367 9.6e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
JGNPNPGP_00368 3.4e-186 2.7.13.3 T GHKL domain
JGNPNPGP_00369 7.1e-61 S Double zinc ribbon
JGNPNPGP_00370 3.3e-50 agrA K LytTr DNA-binding domain
JGNPNPGP_00371 5.6e-48
JGNPNPGP_00372 2.3e-79 S zinc-ribbon domain
JGNPNPGP_00373 1e-74
JGNPNPGP_00376 1.3e-251 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JGNPNPGP_00377 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JGNPNPGP_00378 3.9e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
JGNPNPGP_00379 3.8e-295 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JGNPNPGP_00381 2.2e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
JGNPNPGP_00382 4.8e-210 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JGNPNPGP_00383 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
JGNPNPGP_00384 1.4e-248 U Belongs to the purine-cytosine permease (2.A.39) family
JGNPNPGP_00385 8.1e-243 codA 3.5.4.1 F cytosine deaminase
JGNPNPGP_00386 6.9e-147 tesE Q hydratase
JGNPNPGP_00387 8.1e-114 S (CBS) domain
JGNPNPGP_00388 4.3e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
JGNPNPGP_00389 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JGNPNPGP_00390 2.1e-39 yabO J S4 domain protein
JGNPNPGP_00391 2.3e-57 divIC D Septum formation initiator
JGNPNPGP_00392 9.8e-67 yabR J RNA binding
JGNPNPGP_00393 2.3e-254 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
JGNPNPGP_00394 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
JGNPNPGP_00395 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JGNPNPGP_00396 3e-170 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JGNPNPGP_00397 3.2e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JGNPNPGP_00398 4.2e-294 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
JGNPNPGP_00399 9.2e-87
JGNPNPGP_00400 1.1e-87 acmD M repeat protein
JGNPNPGP_00402 1.2e-101 S enterobacterial common antigen metabolic process
JGNPNPGP_00403 6.7e-186 cps3F
JGNPNPGP_00404 3e-84 M biosynthesis protein
JGNPNPGP_00405 4.2e-36
JGNPNPGP_00406 1.5e-49 M KxYKxGKxW signal domain protein
JGNPNPGP_00407 2.1e-111 M repeat protein
JGNPNPGP_00408 3.7e-25
JGNPNPGP_00409 1.4e-30 S Acyltransferase family
JGNPNPGP_00410 4.4e-36 M Peptidase_C39 like family
JGNPNPGP_00411 1.4e-96 M Glycosyltransferase like family 2
JGNPNPGP_00412 7.1e-100 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JGNPNPGP_00413 1.7e-152 ykoT GT2 M Glycosyl transferase family 2
JGNPNPGP_00414 9.9e-43 S dextransucrase activity
JGNPNPGP_00415 2.9e-159 yueF S AI-2E family transporter
JGNPNPGP_00416 1.5e-161 S Psort location CytoplasmicMembrane, score
JGNPNPGP_00417 4e-217 brpA K Cell envelope-like function transcriptional attenuator common domain protein
JGNPNPGP_00418 2.8e-309 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JGNPNPGP_00419 1.6e-160 hipB K Helix-turn-helix
JGNPNPGP_00420 2.8e-57 yitW S Iron-sulfur cluster assembly protein
JGNPNPGP_00421 2.3e-270 sufB O assembly protein SufB
JGNPNPGP_00422 6.5e-81 nifU C SUF system FeS assembly protein, NifU family
JGNPNPGP_00423 2.6e-233 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JGNPNPGP_00424 1.8e-237 sufD O FeS assembly protein SufD
JGNPNPGP_00425 1.9e-144 sufC O FeS assembly ATPase SufC
JGNPNPGP_00426 1.2e-31 feoA P FeoA domain
JGNPNPGP_00427 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
JGNPNPGP_00428 4.7e-271 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
JGNPNPGP_00429 2.9e-156 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JGNPNPGP_00430 1.6e-64 ydiI Q Thioesterase superfamily
JGNPNPGP_00431 5.4e-109 yvrI K sigma factor activity
JGNPNPGP_00432 1.2e-200 G Transporter, major facilitator family protein
JGNPNPGP_00433 0.0 S Bacterial membrane protein YfhO
JGNPNPGP_00434 1.5e-103 T Ion transport 2 domain protein
JGNPNPGP_00435 2.2e-76 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
JGNPNPGP_00436 4e-223 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
JGNPNPGP_00437 1e-94 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
JGNPNPGP_00438 1.3e-180 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JGNPNPGP_00439 4.1e-127 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
JGNPNPGP_00441 5.6e-201 nupC F Na+ dependent nucleoside transporter C-terminus
JGNPNPGP_00442 9.9e-179 1.1.1.1 C alcohol dehydrogenase
JGNPNPGP_00443 2.6e-72 S Membrane
JGNPNPGP_00444 7.7e-118 trpF 5.3.1.24 E belongs to the TrpF family
JGNPNPGP_00445 2.8e-147 yeiI 2.7.1.15, 2.7.1.45, 2.7.1.83 G Phosphomethylpyrimidine kinase
JGNPNPGP_00446 8.7e-145 psuK 2.7.1.15, 2.7.1.45, 2.7.1.83 GK Winged helix-turn-helix DNA-binding
JGNPNPGP_00448 2.3e-78 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JGNPNPGP_00450 0.0 L PLD-like domain
JGNPNPGP_00451 6.1e-20
JGNPNPGP_00452 1.3e-32 higA K addiction module antidote protein HigA
JGNPNPGP_00454 2.8e-58 yhaI S Protein of unknown function (DUF805)
JGNPNPGP_00455 2.2e-44
JGNPNPGP_00456 0.0 nylA 3.5.1.4 J Belongs to the amidase family
JGNPNPGP_00457 2.4e-22
JGNPNPGP_00458 4.2e-47
JGNPNPGP_00459 2.2e-96 K Acetyltransferase (GNAT) domain
JGNPNPGP_00460 3.8e-295 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
JGNPNPGP_00461 3.1e-218 gntT EG Gluconate
JGNPNPGP_00462 1.2e-183 K Transcriptional regulator, LacI family
JGNPNPGP_00463 5.9e-288 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
JGNPNPGP_00464 7.2e-95
JGNPNPGP_00465 2.3e-24
JGNPNPGP_00466 1.3e-61 asp S Asp23 family, cell envelope-related function
JGNPNPGP_00467 5.3e-89 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
JGNPNPGP_00469 3.5e-49
JGNPNPGP_00470 4.1e-68 yqkB S Belongs to the HesB IscA family
JGNPNPGP_00471 1.9e-172 ppaC 3.6.1.1 C inorganic pyrophosphatase
JGNPNPGP_00472 5.4e-83 F NUDIX domain
JGNPNPGP_00473 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JGNPNPGP_00474 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JGNPNPGP_00475 1.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
JGNPNPGP_00476 2.3e-167 lacX 5.1.3.3 G Aldose 1-epimerase
JGNPNPGP_00477 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JGNPNPGP_00478 1.6e-160 dprA LU DNA protecting protein DprA
JGNPNPGP_00479 4.2e-141 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JGNPNPGP_00480 1.4e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JGNPNPGP_00481 4.4e-35 yozE S Belongs to the UPF0346 family
JGNPNPGP_00482 7.4e-109 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
JGNPNPGP_00483 8e-171 ypmR E lipolytic protein G-D-S-L family
JGNPNPGP_00484 2.2e-151 DegV S EDD domain protein, DegV family
JGNPNPGP_00485 5.3e-113 hlyIII S protein, hemolysin III
JGNPNPGP_00486 8.2e-90 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JGNPNPGP_00487 2.2e-192 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JGNPNPGP_00488 0.0 yfmR S ABC transporter, ATP-binding protein
JGNPNPGP_00489 4.5e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
JGNPNPGP_00490 1.5e-236 S Tetratricopeptide repeat protein
JGNPNPGP_00491 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
JGNPNPGP_00492 2.1e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
JGNPNPGP_00493 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
JGNPNPGP_00494 2.9e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
JGNPNPGP_00495 2.5e-13 M Lysin motif
JGNPNPGP_00496 1.1e-270 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
JGNPNPGP_00497 2.3e-195 ypbB 5.1.3.1 S Helix-turn-helix domain
JGNPNPGP_00498 4.5e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JGNPNPGP_00499 5.9e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
JGNPNPGP_00500 1.7e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JGNPNPGP_00501 7.6e-138 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JGNPNPGP_00502 1.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JGNPNPGP_00503 2.8e-165 xerD D recombinase XerD
JGNPNPGP_00504 9.3e-169 cvfB S S1 domain
JGNPNPGP_00505 1e-270 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
JGNPNPGP_00506 0.0 dnaE 2.7.7.7 L DNA polymerase
JGNPNPGP_00507 2.3e-30 S Protein of unknown function (DUF2929)
JGNPNPGP_00508 4.8e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
JGNPNPGP_00509 1.3e-156 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JGNPNPGP_00510 9.2e-127 trmK 2.1.1.217 S SAM-dependent methyltransferase
JGNPNPGP_00511 4.8e-221 patA 2.6.1.1 E Aminotransferase
JGNPNPGP_00512 1.7e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
JGNPNPGP_00513 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
JGNPNPGP_00514 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
JGNPNPGP_00515 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
JGNPNPGP_00516 8.9e-147 recO L Involved in DNA repair and RecF pathway recombination
JGNPNPGP_00517 5.1e-170 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JGNPNPGP_00518 1.5e-62 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
JGNPNPGP_00519 3.6e-82 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JGNPNPGP_00520 1.5e-183 phoH T phosphate starvation-inducible protein PhoH
JGNPNPGP_00521 1.1e-173 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
JGNPNPGP_00522 3.3e-90 bioY S BioY family
JGNPNPGP_00523 8.3e-265 argH 4.3.2.1 E argininosuccinate lyase
JGNPNPGP_00524 1.3e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
JGNPNPGP_00525 3.5e-185 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
JGNPNPGP_00526 5.6e-69 yqeY S YqeY-like protein
JGNPNPGP_00527 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
JGNPNPGP_00528 4.1e-265 glnPH2 P ABC transporter permease
JGNPNPGP_00529 2.6e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
JGNPNPGP_00530 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
JGNPNPGP_00531 1.4e-169 yniA G Phosphotransferase enzyme family
JGNPNPGP_00532 4.2e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
JGNPNPGP_00533 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JGNPNPGP_00534 1.2e-52
JGNPNPGP_00535 2.2e-131 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
JGNPNPGP_00536 9.8e-180 prmA J Ribosomal protein L11 methyltransferase
JGNPNPGP_00537 2.8e-57
JGNPNPGP_00539 2.6e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
JGNPNPGP_00541 1.1e-198 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
JGNPNPGP_00542 3.7e-276 pipD E Dipeptidase
JGNPNPGP_00543 1e-23 S Coenzyme PQQ synthesis protein D (PqqD)
JGNPNPGP_00544 2.9e-199 S OPT oligopeptide transporter protein
JGNPNPGP_00545 8.5e-106 K IrrE N-terminal-like domain
JGNPNPGP_00546 1.1e-36
JGNPNPGP_00547 9.5e-74 3.5.1.104 M hydrolase, family 25
JGNPNPGP_00548 5.8e-77 ps461 3.5.1.104 M hydrolase, family 25
JGNPNPGP_00549 2e-53 S Bacteriophage holin of superfamily 6 (Holin_LLH)
JGNPNPGP_00553 2.6e-14
JGNPNPGP_00554 1.6e-08
JGNPNPGP_00555 2.8e-33
JGNPNPGP_00556 2.9e-162 3.6.4.12 L Belongs to the 'phage' integrase family
JGNPNPGP_00557 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
JGNPNPGP_00558 5.1e-199 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
JGNPNPGP_00559 0.0 dnaK O Heat shock 70 kDa protein
JGNPNPGP_00560 2.7e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JGNPNPGP_00561 4.1e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
JGNPNPGP_00562 5.8e-64
JGNPNPGP_00563 5e-176 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
JGNPNPGP_00564 9.9e-166 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JGNPNPGP_00565 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JGNPNPGP_00566 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JGNPNPGP_00567 3.8e-48 ylxQ J ribosomal protein
JGNPNPGP_00568 1e-44 ylxR K Protein of unknown function (DUF448)
JGNPNPGP_00569 6.8e-215 nusA K Participates in both transcription termination and antitermination
JGNPNPGP_00570 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
JGNPNPGP_00571 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JGNPNPGP_00572 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
JGNPNPGP_00573 2.8e-235 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
JGNPNPGP_00574 5.8e-138 cdsA 2.7.7.41 I Belongs to the CDS family
JGNPNPGP_00575 9.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JGNPNPGP_00576 4.8e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
JGNPNPGP_00577 2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
JGNPNPGP_00578 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JGNPNPGP_00579 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
JGNPNPGP_00580 2.4e-181 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JGNPNPGP_00581 5.4e-49 yazA L GIY-YIG catalytic domain protein
JGNPNPGP_00582 6.4e-142 yabB 2.1.1.223 L Methyltransferase small domain
JGNPNPGP_00583 1.6e-117 plsC 2.3.1.51 I Acyltransferase
JGNPNPGP_00584 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
JGNPNPGP_00585 1.3e-35 ynzC S UPF0291 protein
JGNPNPGP_00586 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JGNPNPGP_00587 1.3e-210 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
JGNPNPGP_00588 6e-128 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JGNPNPGP_00591 3.5e-19 V Restriction endonuclease
JGNPNPGP_00593 4e-13
JGNPNPGP_00595 4.2e-15
JGNPNPGP_00596 8.4e-16
JGNPNPGP_00597 7.9e-16
JGNPNPGP_00598 8.1e-11
JGNPNPGP_00599 1.2e-31 M MucBP domain
JGNPNPGP_00600 3.8e-130 M MucBP domain
JGNPNPGP_00601 4.1e-19 S there are four paralogs in L.lactis
JGNPNPGP_00602 2.5e-88
JGNPNPGP_00603 1.2e-91 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JGNPNPGP_00604 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
JGNPNPGP_00605 3.2e-155 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
JGNPNPGP_00606 1.3e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
JGNPNPGP_00607 2.3e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JGNPNPGP_00608 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
JGNPNPGP_00609 4.9e-08
JGNPNPGP_00610 1.8e-59 MA20_27270 S mazG nucleotide pyrophosphohydrolase
JGNPNPGP_00611 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
JGNPNPGP_00612 6.2e-235 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JGNPNPGP_00613 8.2e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
JGNPNPGP_00614 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JGNPNPGP_00615 7.8e-163 S Tetratricopeptide repeat
JGNPNPGP_00616 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JGNPNPGP_00617 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JGNPNPGP_00618 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
JGNPNPGP_00619 5.4e-144 holA 2.7.7.7 L DNA polymerase III delta subunit
JGNPNPGP_00620 0.0 comEC S Competence protein ComEC
JGNPNPGP_00621 3.1e-89 comEB 3.5.4.12 F ComE operon protein 2
JGNPNPGP_00622 6.9e-81 comEA L Competence protein ComEA
JGNPNPGP_00623 4.6e-199 ylbL T Belongs to the peptidase S16 family
JGNPNPGP_00624 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JGNPNPGP_00625 6.5e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
JGNPNPGP_00626 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
JGNPNPGP_00627 1.8e-223 ftsW D Belongs to the SEDS family
JGNPNPGP_00628 0.0 typA T GTP-binding protein TypA
JGNPNPGP_00629 9.1e-136 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
JGNPNPGP_00630 1.4e-47 yktA S Belongs to the UPF0223 family
JGNPNPGP_00631 1.4e-275 lpdA 1.8.1.4 C Dehydrogenase
JGNPNPGP_00632 3.5e-228 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
JGNPNPGP_00633 8.1e-182 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
JGNPNPGP_00634 2e-208 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
JGNPNPGP_00635 3.7e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
JGNPNPGP_00636 1.2e-80
JGNPNPGP_00637 9.8e-32 ykzG S Belongs to the UPF0356 family
JGNPNPGP_00638 1.4e-183 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
JGNPNPGP_00639 5.7e-29
JGNPNPGP_00640 8.8e-140 mltD CBM50 M NlpC P60 family protein
JGNPNPGP_00642 2.2e-57
JGNPNPGP_00643 1e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
JGNPNPGP_00644 1.9e-218 EG GntP family permease
JGNPNPGP_00645 2.1e-82 KT Putative sugar diacid recognition
JGNPNPGP_00646 5.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JGNPNPGP_00647 1.4e-220 patA 2.6.1.1 E Aminotransferase
JGNPNPGP_00648 4.3e-141 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
JGNPNPGP_00649 1.2e-174 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JGNPNPGP_00650 1.5e-222 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
JGNPNPGP_00651 3.3e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
JGNPNPGP_00652 1.9e-250 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
JGNPNPGP_00653 6.1e-260 lysC 2.7.2.4 E Belongs to the aspartokinase family
JGNPNPGP_00654 1.1e-170 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JGNPNPGP_00655 3.8e-81 L PFAM transposase IS200-family protein
JGNPNPGP_00656 4.6e-235 UW LPXTG-motif cell wall anchor domain protein
JGNPNPGP_00657 1.8e-55 UW LPXTG-motif cell wall anchor domain protein
JGNPNPGP_00659 4.7e-11 UW LPXTG-motif cell wall anchor domain protein
JGNPNPGP_00660 7.7e-14 L Helix-turn-helix domain
JGNPNPGP_00661 1.8e-124 L Helix-turn-helix domain
JGNPNPGP_00662 5.3e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JGNPNPGP_00663 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
JGNPNPGP_00664 9e-119 S Repeat protein
JGNPNPGP_00665 1.3e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
JGNPNPGP_00666 1.8e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
JGNPNPGP_00667 9.7e-58 XK27_04120 S Putative amino acid metabolism
JGNPNPGP_00668 4.1e-217 iscS 2.8.1.7 E Aminotransferase class V
JGNPNPGP_00669 5e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JGNPNPGP_00671 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
JGNPNPGP_00672 4.2e-32 cspA K Cold shock protein
JGNPNPGP_00673 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JGNPNPGP_00674 2.5e-42 divIVA D DivIVA domain protein
JGNPNPGP_00675 8.4e-145 ylmH S S4 domain protein
JGNPNPGP_00676 3.2e-40 yggT S YGGT family
JGNPNPGP_00677 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
JGNPNPGP_00678 5.3e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JGNPNPGP_00679 3.3e-253 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
JGNPNPGP_00680 2.3e-148 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
JGNPNPGP_00681 1.1e-203 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JGNPNPGP_00682 1.9e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JGNPNPGP_00683 2.6e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JGNPNPGP_00684 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
JGNPNPGP_00685 1.5e-56 ftsL D Cell division protein FtsL
JGNPNPGP_00686 1.6e-174 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
JGNPNPGP_00687 3.1e-77 mraZ K Belongs to the MraZ family
JGNPNPGP_00688 1.7e-57
JGNPNPGP_00689 1.2e-10 S Protein of unknown function (DUF4044)
JGNPNPGP_00690 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
JGNPNPGP_00691 1.8e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
JGNPNPGP_00692 2.2e-159 rrmA 2.1.1.187 H Methyltransferase
JGNPNPGP_00693 9.2e-176 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
JGNPNPGP_00694 4.2e-21 L hmm pf00665
JGNPNPGP_00697 6e-271 pipD E Dipeptidase
JGNPNPGP_00698 0.0 yjbQ P TrkA C-terminal domain protein
JGNPNPGP_00699 1e-24 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
JGNPNPGP_00700 1.3e-290 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JGNPNPGP_00701 3.4e-83
JGNPNPGP_00702 3.3e-36
JGNPNPGP_00703 5.8e-103 K DNA-templated transcription, initiation
JGNPNPGP_00704 4.2e-127
JGNPNPGP_00705 4.6e-67 K Transcriptional regulator, HxlR family
JGNPNPGP_00706 1.5e-167 brpA K Cell envelope-like function transcriptional attenuator common domain protein
JGNPNPGP_00707 2.6e-139 epsB M biosynthesis protein
JGNPNPGP_00708 2.3e-120 ywqD 2.7.10.1 D Capsular exopolysaccharide family
JGNPNPGP_00709 1.3e-103 rfbP M Bacterial sugar transferase
JGNPNPGP_00710 5.8e-75 cpsF M Oligosaccharide biosynthesis protein Alg14 like
JGNPNPGP_00711 1.1e-46 pssE S Glycosyltransferase family 28 C-terminal domain
JGNPNPGP_00712 5.3e-10
JGNPNPGP_00713 1.4e-41 cysE 2.3.1.30 E Hexapeptide repeat of succinyl-transferase
JGNPNPGP_00714 1.8e-78 fcbD 2.7.8.12 GT2 M Glycosyltransferase like family 2
JGNPNPGP_00715 4.9e-70 S Psort location Cytoplasmic, score
JGNPNPGP_00717 1.5e-35 M Glycosyltransferase like family 2
JGNPNPGP_00718 1.4e-164 S Membrane protein involved in the export of O-antigen and teichoic acid
JGNPNPGP_00719 9.8e-96 M Glycosyltransferase
JGNPNPGP_00720 1.3e-84 GT4 M Glycosyltransferase, group 1 family protein
JGNPNPGP_00721 1.8e-72 L Transposase
JGNPNPGP_00722 8.8e-61 L Transposase
JGNPNPGP_00723 1.1e-58 S Protein of unknown function (DUF4065)
JGNPNPGP_00725 6.2e-171 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
JGNPNPGP_00726 1e-246 mmuP E amino acid
JGNPNPGP_00728 8.8e-68 T Toxin-antitoxin system, toxin component, MazF family
JGNPNPGP_00729 1e-37
JGNPNPGP_00731 7e-144 ywqE 3.1.3.48 GM PHP domain protein
JGNPNPGP_00732 4.4e-177 M Glycosyl hydrolases family 25
JGNPNPGP_00733 2.9e-207 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
JGNPNPGP_00734 0.0 sbcC L Putative exonuclease SbcCD, C subunit
JGNPNPGP_00735 1.1e-87 L nuclease
JGNPNPGP_00736 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
JGNPNPGP_00737 4.8e-70
JGNPNPGP_00738 1.1e-101 fic D Fic/DOC family
JGNPNPGP_00739 7.3e-124 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
JGNPNPGP_00740 4.4e-152 3.1.3.73 G Belongs to the phosphoglycerate mutase family
JGNPNPGP_00741 8.7e-30
JGNPNPGP_00742 7.1e-62
JGNPNPGP_00743 5.4e-25
JGNPNPGP_00744 1.6e-53 M NlpC P60 family protein
JGNPNPGP_00745 4.8e-56 M Peptidase_C39 like family
JGNPNPGP_00746 4.5e-55 ponA V the current gene model (or a revised gene model) may contain a frame shift
JGNPNPGP_00747 9.3e-65 gntR1 K Transcriptional regulator, GntR family
JGNPNPGP_00748 1e-156 V ABC transporter, ATP-binding protein
JGNPNPGP_00749 1.1e-111
JGNPNPGP_00750 7.3e-96 S TraX protein
JGNPNPGP_00751 8e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
JGNPNPGP_00752 7e-99 S Pfam:DUF3816
JGNPNPGP_00753 0.0 clpE O Belongs to the ClpA ClpB family
JGNPNPGP_00754 2.9e-27
JGNPNPGP_00755 2.7e-39 ptsH G phosphocarrier protein HPR
JGNPNPGP_00756 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JGNPNPGP_00757 1.2e-227 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
JGNPNPGP_00758 1.3e-198 cpoA GT4 M Glycosyltransferase, group 1 family protein
JGNPNPGP_00759 3.9e-179 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JGNPNPGP_00760 1.5e-39 ykuJ S Protein of unknown function (DUF1797)
JGNPNPGP_00761 5.7e-94 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
JGNPNPGP_00762 1.6e-182 I Alpha beta
JGNPNPGP_00763 2.3e-279 emrY EGP Major facilitator Superfamily
JGNPNPGP_00764 1.2e-117 ung2 3.2.2.27 L Uracil-DNA glycosylase
JGNPNPGP_00765 9.4e-253 yjjP S Putative threonine/serine exporter
JGNPNPGP_00766 1.5e-158 mleR K LysR family
JGNPNPGP_00767 1.3e-252 yflS P Sodium:sulfate symporter transmembrane region
JGNPNPGP_00768 9.9e-266 frdC 1.3.5.4 C FAD binding domain
JGNPNPGP_00769 2.1e-260 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
JGNPNPGP_00770 4.1e-303 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
JGNPNPGP_00771 2.2e-157 mleR K LysR family
JGNPNPGP_00772 3.9e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JGNPNPGP_00773 1.6e-204 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
JGNPNPGP_00774 5.8e-263 L PFAM plasmid pRiA4b ORF-3 family protein
JGNPNPGP_00775 0.0 fhaB M Rib/alpha-like repeat
JGNPNPGP_00776 5.3e-247 fhaB M Rib/alpha-like repeat
JGNPNPGP_00777 1e-122 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
JGNPNPGP_00778 2.1e-200 2.7.7.65 T GGDEF domain
JGNPNPGP_00779 1.5e-86
JGNPNPGP_00780 1.9e-253 pgaC GT2 M Glycosyl transferase
JGNPNPGP_00781 1.1e-139 T EAL domain
JGNPNPGP_00782 5.5e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
JGNPNPGP_00783 8.2e-63 yneR
JGNPNPGP_00784 5.6e-102 qorB 1.6.5.2 GM NmrA-like family
JGNPNPGP_00786 1.6e-109 GM NAD(P)H-binding
JGNPNPGP_00787 3.7e-186 S membrane
JGNPNPGP_00788 1.2e-103 K Transcriptional regulator C-terminal region
JGNPNPGP_00789 2.4e-161 akr5f 1.1.1.346 S reductase
JGNPNPGP_00790 6.4e-138 K Transcriptional regulator
JGNPNPGP_00791 5.2e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
JGNPNPGP_00792 4e-91 L Integrase
JGNPNPGP_00793 2.8e-95 cadD P Cadmium resistance transporter
JGNPNPGP_00794 1.9e-56 cadX K Bacterial regulatory protein, arsR family
JGNPNPGP_00795 2.9e-69 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JGNPNPGP_00796 2.8e-175 arsB 1.20.4.1 P Sodium Bile acid symporter family
JGNPNPGP_00797 2.4e-34 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
JGNPNPGP_00798 2.2e-09 S HTH domain
JGNPNPGP_00801 1.8e-10
JGNPNPGP_00802 2.8e-82 L Phage integrase, N-terminal SAM-like domain
JGNPNPGP_00803 1.5e-36 L Single-strand binding protein family
JGNPNPGP_00804 2.3e-102 L Replication initiation factor
JGNPNPGP_00805 1.5e-18 yqfZ 3.2.1.17 M hydrolase, family 25
JGNPNPGP_00806 1.4e-58 L Initiator Replication protein
JGNPNPGP_00807 1.4e-06 S DNA repair protein MmcB-like
JGNPNPGP_00808 4.4e-304 uup S ABC transporter, ATP-binding protein
JGNPNPGP_00809 9e-113 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JGNPNPGP_00810 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JGNPNPGP_00811 1.9e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
JGNPNPGP_00812 6.3e-82 S Aminoacyl-tRNA editing domain
JGNPNPGP_00813 9.6e-305 ybeC E amino acid
JGNPNPGP_00814 0.0 ydaO E amino acid
JGNPNPGP_00815 4.6e-39
JGNPNPGP_00816 1.6e-67 rmaI K Transcriptional regulator
JGNPNPGP_00817 6e-239 EGP Major facilitator Superfamily
JGNPNPGP_00818 2.2e-129 ponA V Beta-lactamase enzyme family
JGNPNPGP_00819 6.6e-221 dacA 3.4.16.4 M Belongs to the peptidase S11 family
JGNPNPGP_00820 6.7e-75
JGNPNPGP_00821 1.3e-201 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
JGNPNPGP_00822 9.8e-22
JGNPNPGP_00825 1.7e-265 S Uncharacterized protein conserved in bacteria (DUF2252)
JGNPNPGP_00826 3.2e-27 L PFAM plasmid pRiA4b ORF-3 family protein
JGNPNPGP_00827 1.9e-95 lytE M LysM domain protein
JGNPNPGP_00828 0.0 oppD EP Psort location Cytoplasmic, score
JGNPNPGP_00829 2.1e-42 lytE M LysM domain protein
JGNPNPGP_00830 7.5e-158 sufD O Uncharacterized protein family (UPF0051)
JGNPNPGP_00831 9e-112 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JGNPNPGP_00832 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
JGNPNPGP_00833 2.6e-234 lmrB EGP Major facilitator Superfamily
JGNPNPGP_00834 2.4e-98 2.3.1.128 K Acetyltransferase (GNAT) domain
JGNPNPGP_00835 9.6e-21 comGA NU Type II IV secretion system protein
JGNPNPGP_00836 3.8e-131 yebC K Transcriptional regulatory protein
JGNPNPGP_00837 1e-135
JGNPNPGP_00838 5.5e-181 ccpA K catabolite control protein A
JGNPNPGP_00839 1.9e-211 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
JGNPNPGP_00840 4.9e-28
JGNPNPGP_00841 6.5e-38 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JGNPNPGP_00842 8.1e-149 ykuT M mechanosensitive ion channel
JGNPNPGP_00843 5.8e-152 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
JGNPNPGP_00844 5.1e-75 ykuL S (CBS) domain
JGNPNPGP_00845 5.9e-94 S Phosphoesterase
JGNPNPGP_00846 5e-102 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JGNPNPGP_00847 2.8e-140 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
JGNPNPGP_00848 1.3e-96 yslB S Protein of unknown function (DUF2507)
JGNPNPGP_00849 6.1e-54 trxA O Belongs to the thioredoxin family
JGNPNPGP_00850 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
JGNPNPGP_00851 1.6e-86 cvpA S Colicin V production protein
JGNPNPGP_00852 6.1e-48 yrzB S Belongs to the UPF0473 family
JGNPNPGP_00853 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JGNPNPGP_00854 4.1e-43 yrzL S Belongs to the UPF0297 family
JGNPNPGP_00855 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JGNPNPGP_00856 3.7e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
JGNPNPGP_00857 4.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
JGNPNPGP_00858 2.8e-31 yajC U Preprotein translocase
JGNPNPGP_00859 3.9e-193 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
JGNPNPGP_00860 3.4e-191 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
JGNPNPGP_00861 1.5e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
JGNPNPGP_00862 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JGNPNPGP_00863 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JGNPNPGP_00864 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
JGNPNPGP_00865 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JGNPNPGP_00866 3.9e-229 cinA 3.5.1.42 S Belongs to the CinA family
JGNPNPGP_00867 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JGNPNPGP_00868 3.4e-138 ymfM S Helix-turn-helix domain
JGNPNPGP_00869 6.7e-248 ymfH S Peptidase M16
JGNPNPGP_00870 5.1e-229 ymfF S Peptidase M16 inactive domain protein
JGNPNPGP_00871 2.6e-160 aatB ET ABC transporter substrate-binding protein
JGNPNPGP_00872 2.1e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
JGNPNPGP_00873 3.2e-102 glnP P ABC transporter permease
JGNPNPGP_00874 8.7e-93 mreD M rod shape-determining protein MreD
JGNPNPGP_00875 5e-151 mreC M Involved in formation and maintenance of cell shape
JGNPNPGP_00876 1.7e-179 mreB D cell shape determining protein MreB
JGNPNPGP_00877 4.7e-122 radC L DNA repair protein
JGNPNPGP_00878 5.9e-244 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
JGNPNPGP_00879 9e-231 ndh 1.6.99.3 C NADH dehydrogenase
JGNPNPGP_00880 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JGNPNPGP_00881 1.1e-308 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
JGNPNPGP_00882 4.1e-184 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
JGNPNPGP_00883 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
JGNPNPGP_00884 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
JGNPNPGP_00885 8.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JGNPNPGP_00886 1e-215 iscS2 2.8.1.7 E Aminotransferase class V
JGNPNPGP_00887 4.5e-252 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JGNPNPGP_00888 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JGNPNPGP_00889 2.1e-236 pbuG S permease
JGNPNPGP_00890 2.3e-270 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
JGNPNPGP_00891 9.9e-184 gadC E amino acid
JGNPNPGP_00892 1.1e-96 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
JGNPNPGP_00893 5.7e-263 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
JGNPNPGP_00894 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
JGNPNPGP_00895 6.5e-139 S Belongs to the UPF0246 family
JGNPNPGP_00896 9.4e-138 S Membrane
JGNPNPGP_00897 8.1e-75 4.4.1.5 E Glyoxalase
JGNPNPGP_00898 1.5e-21
JGNPNPGP_00899 2.2e-74 yueI S Protein of unknown function (DUF1694)
JGNPNPGP_00900 1.2e-241 rarA L recombination factor protein RarA
JGNPNPGP_00901 5.7e-46
JGNPNPGP_00902 4.3e-83 usp6 T universal stress protein
JGNPNPGP_00903 3.7e-207 araR K Transcriptional regulator
JGNPNPGP_00904 4.1e-158 ytbE 1.1.1.346 S Aldo keto reductase
JGNPNPGP_00905 2.9e-99 maa 2.3.1.79 S Maltose O-acetyltransferase
JGNPNPGP_00906 9.7e-285 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
JGNPNPGP_00907 4.9e-139 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
JGNPNPGP_00908 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
JGNPNPGP_00909 7.5e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
JGNPNPGP_00910 7.7e-147 K transcriptional regulator, ArsR family
JGNPNPGP_00911 4.8e-174 abf G Belongs to the glycosyl hydrolase 43 family
JGNPNPGP_00912 2.3e-216 lacY G Oligosaccharide H symporter
JGNPNPGP_00913 3e-148 2.3.1.19 K Helix-turn-helix XRE-family like proteins
JGNPNPGP_00914 1.8e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
JGNPNPGP_00915 1.4e-47 gcvH E glycine cleavage
JGNPNPGP_00916 1.1e-220 rodA D Belongs to the SEDS family
JGNPNPGP_00917 1e-31 S Protein of unknown function (DUF2969)
JGNPNPGP_00918 1.9e-178 mbl D Cell shape determining protein MreB Mrl
JGNPNPGP_00919 1.9e-242 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JGNPNPGP_00920 1.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
JGNPNPGP_00921 9.2e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JGNPNPGP_00922 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JGNPNPGP_00923 3.4e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JGNPNPGP_00924 4.3e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JGNPNPGP_00925 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JGNPNPGP_00926 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JGNPNPGP_00927 4.7e-123 atpB C it plays a direct role in the translocation of protons across the membrane
JGNPNPGP_00928 5.9e-233 pyrP F Permease
JGNPNPGP_00929 2e-130 yibF S overlaps another CDS with the same product name
JGNPNPGP_00930 1.7e-191 yibE S overlaps another CDS with the same product name
JGNPNPGP_00931 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JGNPNPGP_00932 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JGNPNPGP_00933 1.1e-228 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JGNPNPGP_00934 3e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
JGNPNPGP_00935 8.6e-167 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
JGNPNPGP_00936 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JGNPNPGP_00937 6e-108 tdk 2.7.1.21 F thymidine kinase
JGNPNPGP_00938 2e-263 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
JGNPNPGP_00939 3.2e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
JGNPNPGP_00940 1.4e-222 arcD U Amino acid permease
JGNPNPGP_00941 2.8e-260 E Arginine ornithine antiporter
JGNPNPGP_00942 2.7e-79 argR K Regulates arginine biosynthesis genes
JGNPNPGP_00943 3.5e-238 arcA 3.5.3.6 E Arginine
JGNPNPGP_00944 5.7e-194 ampC V Beta-lactamase
JGNPNPGP_00945 5.8e-21
JGNPNPGP_00946 0.0 M domain protein
JGNPNPGP_00947 1.6e-88
JGNPNPGP_00949 6.3e-253 yjcE P Sodium proton antiporter
JGNPNPGP_00950 3.6e-57
JGNPNPGP_00952 7.4e-88
JGNPNPGP_00953 0.0 copA 3.6.3.54 P P-type ATPase
JGNPNPGP_00954 2.4e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
JGNPNPGP_00955 2.4e-54 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
JGNPNPGP_00956 6.5e-102 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
JGNPNPGP_00957 6.6e-162 EG EamA-like transporter family
JGNPNPGP_00958 5.6e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
JGNPNPGP_00959 5.8e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JGNPNPGP_00960 4.7e-154 KT YcbB domain
JGNPNPGP_00961 0.0 3.2.1.21 GH3 G hydrolase, family 3
JGNPNPGP_00962 8.9e-168 3.2.1.58 G Cellulase (glycosyl hydrolase family 5)
JGNPNPGP_00963 7e-178 blt G MFS/sugar transport protein
JGNPNPGP_00964 0.0 lacZ3 3.2.1.23 G Beta-galactosidase
JGNPNPGP_00965 3.2e-124 K helix_turn_helix, arabinose operon control protein
JGNPNPGP_00966 1.6e-275 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
JGNPNPGP_00967 4.6e-85 3.2.1.37 GH43 K helix_turn_helix, arabinose operon control protein
JGNPNPGP_00968 1.1e-299 xylB 2.7.1.17 G Belongs to the FGGY kinase family
JGNPNPGP_00969 7.6e-271 xylA 5.3.1.5 G Belongs to the xylose isomerase family
JGNPNPGP_00970 0.0 yicI 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
JGNPNPGP_00971 6.7e-238 xynP G MFS/sugar transport protein
JGNPNPGP_00972 8e-136 xylR GK ROK family
JGNPNPGP_00973 0.0 3.2.1.55 GH51 G Right handed beta helix region
JGNPNPGP_00974 1.6e-290 xynT G MFS/sugar transport protein
JGNPNPGP_00975 1.1e-172 rhaS2 K Transcriptional regulator, AraC family
JGNPNPGP_00976 3.7e-260 xylT EGP Major facilitator Superfamily
JGNPNPGP_00978 5.5e-217 xylR GK ROK family
JGNPNPGP_00979 1.3e-28
JGNPNPGP_00980 3.4e-263 pgi 5.3.1.9 G Belongs to the GPI family
JGNPNPGP_00981 8.9e-102 lacA 2.3.1.79 S Transferase hexapeptide repeat
JGNPNPGP_00982 9.8e-155 glcU U sugar transport
JGNPNPGP_00983 2.4e-273 yclK 2.7.13.3 T Histidine kinase
JGNPNPGP_00984 3e-133 K response regulator
JGNPNPGP_00986 9e-78 lytE M Lysin motif
JGNPNPGP_00987 6.6e-145 XK27_02985 S Cof-like hydrolase
JGNPNPGP_00988 1.8e-78 K Transcriptional regulator
JGNPNPGP_00989 0.0 oatA I Acyltransferase
JGNPNPGP_00990 4.8e-51
JGNPNPGP_00991 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
JGNPNPGP_00992 3.2e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JGNPNPGP_00993 5.8e-126 ybbR S YbbR-like protein
JGNPNPGP_00994 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JGNPNPGP_00995 3.7e-249 fucP G Major Facilitator Superfamily
JGNPNPGP_00996 1e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
JGNPNPGP_00997 2.7e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JGNPNPGP_00998 3.6e-168 murB 1.3.1.98 M Cell wall formation
JGNPNPGP_00999 1.7e-101 dnaQ 2.7.7.7 L DNA polymerase III
JGNPNPGP_01000 1.7e-75 S PAS domain
JGNPNPGP_01001 1.8e-87 K Acetyltransferase (GNAT) domain
JGNPNPGP_01002 2.9e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
JGNPNPGP_01003 3.8e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
JGNPNPGP_01004 1.8e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JGNPNPGP_01005 6.3e-105 yxjI
JGNPNPGP_01006 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
JGNPNPGP_01007 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
JGNPNPGP_01008 4.4e-146 est 3.1.1.1 S Serine aminopeptidase, S33
JGNPNPGP_01009 1.8e-34 secG U Preprotein translocase
JGNPNPGP_01010 8.1e-293 clcA P chloride
JGNPNPGP_01011 9.2e-248 yifK E Amino acid permease
JGNPNPGP_01012 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
JGNPNPGP_01013 1.4e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
JGNPNPGP_01014 2.4e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
JGNPNPGP_01015 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
JGNPNPGP_01017 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
JGNPNPGP_01018 8.8e-243 glpT G Major Facilitator Superfamily
JGNPNPGP_01019 8.8e-15
JGNPNPGP_01021 4e-170 whiA K May be required for sporulation
JGNPNPGP_01022 6.5e-187 ybhK S Required for morphogenesis under gluconeogenic growth conditions
JGNPNPGP_01023 9.2e-161 rapZ S Displays ATPase and GTPase activities
JGNPNPGP_01024 2.4e-245 steT E amino acid
JGNPNPGP_01025 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
JGNPNPGP_01026 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
JGNPNPGP_01027 1.5e-13
JGNPNPGP_01028 2.3e-116 yfbR S HD containing hydrolase-like enzyme
JGNPNPGP_01029 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
JGNPNPGP_01030 2.1e-88 ykhA 3.1.2.20 I Thioesterase superfamily
JGNPNPGP_01031 1.4e-161 aatB ET PFAM extracellular solute-binding protein, family 3
JGNPNPGP_01032 3.7e-205 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
JGNPNPGP_01033 2.3e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
JGNPNPGP_01034 8.1e-159 lutA C Cysteine-rich domain
JGNPNPGP_01035 7e-294 lutB C 4Fe-4S dicluster domain
JGNPNPGP_01036 1.5e-135 yrjD S LUD domain
JGNPNPGP_01037 1.5e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
JGNPNPGP_01038 1e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
JGNPNPGP_01039 1.1e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JGNPNPGP_01040 4.6e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JGNPNPGP_01041 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
JGNPNPGP_01042 3.1e-32 KT PspC domain protein
JGNPNPGP_01043 3.9e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JGNPNPGP_01044 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
JGNPNPGP_01045 3e-93 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JGNPNPGP_01046 7.1e-116 comFC S Competence protein
JGNPNPGP_01047 1.5e-250 comFA L Helicase C-terminal domain protein
JGNPNPGP_01048 2e-109 yvyE 3.4.13.9 S YigZ family
JGNPNPGP_01049 6e-23 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
JGNPNPGP_01050 4.7e-10 T PFAM SpoVT AbrB
JGNPNPGP_01051 1.3e-96 S N-acetylmuramoyl-L-alanine amidase activity
JGNPNPGP_01052 5.1e-25 S Bacteriophage holin of superfamily 6 (Holin_LLH)
JGNPNPGP_01053 2.7e-40
JGNPNPGP_01056 4.6e-65 G cellulose 1,4-beta-cellobiosidase activity
JGNPNPGP_01057 4.6e-23
JGNPNPGP_01058 2.5e-119 Z012_12235 S Baseplate J-like protein
JGNPNPGP_01059 3.7e-09 S Protein of unknown function (DUF2634)
JGNPNPGP_01060 4.3e-27
JGNPNPGP_01061 3.2e-89
JGNPNPGP_01062 6.7e-35
JGNPNPGP_01063 7e-53 3.5.1.28 M LysM domain
JGNPNPGP_01064 8.1e-13
JGNPNPGP_01084 1.5e-75 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
JGNPNPGP_01085 6.1e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
JGNPNPGP_01086 1.4e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
JGNPNPGP_01087 4e-203 coiA 3.6.4.12 S Competence protein
JGNPNPGP_01088 1.9e-261 pipD E Dipeptidase
JGNPNPGP_01089 4.7e-114 yjbH Q Thioredoxin
JGNPNPGP_01090 5.2e-116 yjbM 2.7.6.5 S RelA SpoT domain protein
JGNPNPGP_01091 2.7e-154 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JGNPNPGP_01092 1.6e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
JGNPNPGP_01093 1e-44 rpmA J Belongs to the bacterial ribosomal protein bL27 family
JGNPNPGP_01094 3.7e-54 ysxB J Cysteine protease Prp
JGNPNPGP_01095 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
JGNPNPGP_01096 2.6e-112 K Transcriptional regulator
JGNPNPGP_01099 1.1e-89 dut S Protein conserved in bacteria
JGNPNPGP_01100 4.9e-177
JGNPNPGP_01101 3e-151
JGNPNPGP_01102 1.3e-51 S Iron-sulfur cluster assembly protein
JGNPNPGP_01103 3.6e-99 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JGNPNPGP_01104 2.8e-154 P Belongs to the nlpA lipoprotein family
JGNPNPGP_01105 6.1e-109 dedA S SNARE-like domain protein
JGNPNPGP_01106 1.7e-106 S Protein of unknown function (DUF1461)
JGNPNPGP_01107 1.1e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
JGNPNPGP_01108 6e-94 yutD S Protein of unknown function (DUF1027)
JGNPNPGP_01109 2.2e-113 S Calcineurin-like phosphoesterase
JGNPNPGP_01110 1.2e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JGNPNPGP_01111 1.7e-145 ytxK 2.1.1.72 L N-6 DNA Methylase
JGNPNPGP_01113 8.3e-70
JGNPNPGP_01114 2.4e-41
JGNPNPGP_01115 2.2e-78 NU general secretion pathway protein
JGNPNPGP_01116 7.1e-47 comGC U competence protein ComGC
JGNPNPGP_01117 4.1e-184 comGB NU type II secretion system
JGNPNPGP_01118 5.3e-147 comGA NU Type II IV secretion system protein
JGNPNPGP_01120 1.6e-11 D nuclear chromosome segregation
JGNPNPGP_01122 1.4e-160 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
JGNPNPGP_01123 1.4e-43 hxlR K Transcriptional regulator, HxlR family
JGNPNPGP_01124 1.4e-74 L Transposase
JGNPNPGP_01126 2.7e-155 spoU 2.1.1.185 J Methyltransferase
JGNPNPGP_01127 5.3e-160 ypuA S Protein of unknown function (DUF1002)
JGNPNPGP_01128 4.5e-66 GM NAD(P)H-binding
JGNPNPGP_01129 3.6e-91 padR K Virulence activator alpha C-term
JGNPNPGP_01130 2.7e-94 padC Q Phenolic acid decarboxylase
JGNPNPGP_01131 5.4e-67 XK27_01125 L PFAM IS66 Orf2 family protein
JGNPNPGP_01133 1.3e-262 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
JGNPNPGP_01134 1.1e-255 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
JGNPNPGP_01135 4.9e-198 asnA 6.3.1.1 F aspartate--ammonia ligase
JGNPNPGP_01136 5.9e-92 folT S ECF transporter, substrate-specific component
JGNPNPGP_01137 7.2e-48 K Transcriptional regulator
JGNPNPGP_01138 0.0 pepN 3.4.11.2 E aminopeptidase
JGNPNPGP_01139 8.4e-111 ylbE GM NAD dependent epimerase dehydratase family protein
JGNPNPGP_01140 1.7e-254 pepC 3.4.22.40 E aminopeptidase
JGNPNPGP_01141 1.6e-208 EGP Major facilitator Superfamily
JGNPNPGP_01142 6.5e-235
JGNPNPGP_01143 6.2e-84 K Transcriptional regulator, HxlR family
JGNPNPGP_01144 4.8e-108 XK27_02070 S Nitroreductase family
JGNPNPGP_01145 5.3e-50 hxlR K Transcriptional regulator, HxlR family
JGNPNPGP_01146 1.2e-120 GM NmrA-like family
JGNPNPGP_01147 8.7e-75 elaA S Gnat family
JGNPNPGP_01148 1.8e-39 S Cytochrome B5
JGNPNPGP_01149 5.4e-09 S Cytochrome B5
JGNPNPGP_01150 1.6e-41 S Cytochrome B5
JGNPNPGP_01151 1.7e-210 yxjG_1 E methionine synthase, vitamin-B12 independent
JGNPNPGP_01152 7.9e-14 S Protein of unknown function (DUF3278)
JGNPNPGP_01153 2.9e-27 WQ51_00220 K Helix-turn-helix XRE-family like proteins
JGNPNPGP_01154 1e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JGNPNPGP_01155 3.7e-241 E amino acid
JGNPNPGP_01156 1.5e-258 npp S type I phosphodiesterase nucleotide pyrophosphatase
JGNPNPGP_01157 1.9e-223 yxiO S Vacuole effluxer Atg22 like
JGNPNPGP_01159 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JGNPNPGP_01160 7.3e-28
JGNPNPGP_01161 8.9e-287 mntH P H( )-stimulated, divalent metal cation uptake system
JGNPNPGP_01162 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
JGNPNPGP_01163 8e-88 ygfC K transcriptional regulator (TetR family)
JGNPNPGP_01164 8.3e-172 hrtB V ABC transporter permease
JGNPNPGP_01165 5.3e-119 devA 3.6.3.25 V ABC transporter, ATP-binding protein
JGNPNPGP_01166 0.0 yhcA V ABC transporter, ATP-binding protein
JGNPNPGP_01167 2.5e-36
JGNPNPGP_01168 7e-50 czrA K Transcriptional regulator, ArsR family
JGNPNPGP_01169 4.5e-228 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
JGNPNPGP_01170 1.5e-172 scrR K Transcriptional regulator, LacI family
JGNPNPGP_01171 1e-24
JGNPNPGP_01172 1.6e-106
JGNPNPGP_01173 1.4e-215 yttB EGP Major facilitator Superfamily
JGNPNPGP_01174 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
JGNPNPGP_01175 2.4e-89
JGNPNPGP_01176 7.2e-104 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
JGNPNPGP_01177 1.3e-262 S Putative peptidoglycan binding domain
JGNPNPGP_01178 5.2e-124 yciB M ErfK YbiS YcfS YnhG
JGNPNPGP_01180 2.2e-102
JGNPNPGP_01181 3.5e-219 dacA 3.4.16.4 M Belongs to the peptidase S11 family
JGNPNPGP_01182 3.6e-125 S Alpha beta hydrolase
JGNPNPGP_01183 2.4e-206 gldA 1.1.1.6 C dehydrogenase
JGNPNPGP_01184 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
JGNPNPGP_01185 3.8e-41
JGNPNPGP_01186 2.5e-126 pgm3 3.1.3.73 G phosphoglycerate mutase family
JGNPNPGP_01187 8.1e-285 S C4-dicarboxylate anaerobic carrier
JGNPNPGP_01188 9.1e-251 nhaC C Na H antiporter NhaC
JGNPNPGP_01189 7.3e-242 pbuX F xanthine permease
JGNPNPGP_01190 3e-281 pipD E Dipeptidase
JGNPNPGP_01191 1.5e-166 corA P CorA-like Mg2+ transporter protein
JGNPNPGP_01192 7.7e-166 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JGNPNPGP_01193 3e-131 terC P membrane
JGNPNPGP_01194 7.2e-55 trxA O Belongs to the thioredoxin family
JGNPNPGP_01195 9.8e-239 mepA V MATE efflux family protein
JGNPNPGP_01196 8.9e-56 K Transcriptional regulator, ArsR family
JGNPNPGP_01197 3.2e-90 P Cadmium resistance transporter
JGNPNPGP_01198 3.7e-137 XK27_08845 S ABC transporter, ATP-binding protein
JGNPNPGP_01199 1.1e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
JGNPNPGP_01200 3.7e-182 ABC-SBP S ABC transporter
JGNPNPGP_01201 9.9e-226 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
JGNPNPGP_01202 1.7e-73 M PFAM NLP P60 protein
JGNPNPGP_01203 1.4e-99 S Protein of unknown function (DUF3278)
JGNPNPGP_01204 6.7e-31 WQ51_00220 K Helix-turn-helix domain
JGNPNPGP_01205 1.3e-48
JGNPNPGP_01206 1.9e-273 S ABC transporter, ATP-binding protein
JGNPNPGP_01207 5.9e-143 S Putative ABC-transporter type IV
JGNPNPGP_01208 5.8e-106 NU mannosyl-glycoprotein
JGNPNPGP_01209 2.4e-248 brnQ U Component of the transport system for branched-chain amino acids
JGNPNPGP_01210 2e-230 S Uncharacterized protein conserved in bacteria (DUF2325)
JGNPNPGP_01211 1.6e-202 nrnB S DHHA1 domain
JGNPNPGP_01212 6.3e-50
JGNPNPGP_01213 6.3e-137 2.1.1.72 D peptidase
JGNPNPGP_01214 1.9e-18 S Domain of unknown function (DUF4767)
JGNPNPGP_01215 1.8e-53
JGNPNPGP_01216 7.1e-116 yrkL S Flavodoxin-like fold
JGNPNPGP_01218 1.5e-64 yeaO S Protein of unknown function, DUF488
JGNPNPGP_01219 3.4e-120 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
JGNPNPGP_01220 7.3e-206 3.1.3.1 S associated with various cellular activities
JGNPNPGP_01221 6.3e-106 S Putative metallopeptidase domain
JGNPNPGP_01222 5.4e-121 S Putative metallopeptidase domain
JGNPNPGP_01223 3e-47
JGNPNPGP_01224 0.0 pepO 3.4.24.71 O Peptidase family M13
JGNPNPGP_01225 7.1e-110 K Helix-turn-helix domain
JGNPNPGP_01226 7.9e-88 ymdB S Macro domain protein
JGNPNPGP_01227 7.4e-198 EGP Major facilitator Superfamily
JGNPNPGP_01228 2.9e-287 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JGNPNPGP_01229 2.7e-54 K helix_turn_helix, mercury resistance
JGNPNPGP_01230 4.4e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
JGNPNPGP_01231 8.2e-159 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
JGNPNPGP_01232 0.0 ysaB V FtsX-like permease family
JGNPNPGP_01233 2.6e-135 macB2 V ABC transporter, ATP-binding protein
JGNPNPGP_01234 3.4e-164 T PhoQ Sensor
JGNPNPGP_01235 2.2e-125 K response regulator
JGNPNPGP_01236 2.3e-156 ytbE 1.1.1.346 S Aldo keto reductase
JGNPNPGP_01237 2e-135 pnuC H nicotinamide mononucleotide transporter
JGNPNPGP_01238 7.5e-83 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
JGNPNPGP_01239 2.3e-204
JGNPNPGP_01240 3.5e-52
JGNPNPGP_01241 9.1e-36
JGNPNPGP_01242 6.3e-93 yxkA S Phosphatidylethanolamine-binding protein
JGNPNPGP_01243 1.4e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
JGNPNPGP_01244 4e-181 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
JGNPNPGP_01245 1.4e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JGNPNPGP_01246 6.7e-281 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
JGNPNPGP_01247 1.2e-180 galR K Transcriptional regulator
JGNPNPGP_01248 2.7e-98 dedA 3.1.3.1 S SNARE associated Golgi protein
JGNPNPGP_01249 2e-231 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
JGNPNPGP_01250 5.6e-80 K AsnC family
JGNPNPGP_01251 3.3e-80 uspA T universal stress protein
JGNPNPGP_01252 1.1e-129 ltrA S Bacterial low temperature requirement A protein (LtrA)
JGNPNPGP_01253 0.0 lacS G Transporter
JGNPNPGP_01254 4.2e-40
JGNPNPGP_01255 1.4e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JGNPNPGP_01256 7.5e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JGNPNPGP_01257 3.1e-193 yeaN P Transporter, major facilitator family protein
JGNPNPGP_01258 4.2e-74 S 3-demethylubiquinone-9 3-methyltransferase
JGNPNPGP_01259 1.3e-84 nrdI F Belongs to the NrdI family
JGNPNPGP_01260 2.8e-241 yhdP S Transporter associated domain
JGNPNPGP_01261 5.2e-156 ypdB V (ABC) transporter
JGNPNPGP_01262 7.9e-91 1.14.14.47, 1.6.5.3, 1.6.99.3 GM epimerase
JGNPNPGP_01263 3.6e-91 M1-874 K Domain of unknown function (DUF1836)
JGNPNPGP_01264 6.6e-78 yybA 2.3.1.57 K Transcriptional regulator
JGNPNPGP_01265 4.2e-135 XK27_07210 6.1.1.6 S B3 4 domain
JGNPNPGP_01266 1.2e-173 S AI-2E family transporter
JGNPNPGP_01267 1.7e-159 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
JGNPNPGP_01268 8.8e-162
JGNPNPGP_01269 1.5e-87 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
JGNPNPGP_01270 2e-149 eutJ E Hsp70 protein
JGNPNPGP_01271 3.3e-200 K helix_turn_helix, arabinose operon control protein
JGNPNPGP_01272 6.2e-42 pduA_4 CQ BMC
JGNPNPGP_01273 2.7e-134 pduB E BMC
JGNPNPGP_01274 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
JGNPNPGP_01275 7.1e-127 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
JGNPNPGP_01276 1.1e-79 pduE 4.2.1.28 Q Dehydratase small subunit
JGNPNPGP_01277 0.0 pduG D Diol dehydratase reactivase ATPase-like domain
JGNPNPGP_01278 1.7e-60 pduH S Dehydratase medium subunit
JGNPNPGP_01279 5.1e-75 pduK CQ BMC
JGNPNPGP_01280 7.6e-43 pduA_4 CQ BMC
JGNPNPGP_01281 4.2e-118 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
JGNPNPGP_01282 6.4e-90 S Putative propanediol utilisation
JGNPNPGP_01283 1.2e-40 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
JGNPNPGP_01284 8.3e-105 pduO 2.5.1.17 S Cobalamin adenosyltransferase
JGNPNPGP_01285 7.4e-80 pduO S Haem-degrading
JGNPNPGP_01286 3.1e-270 pduP 1.2.1.87 C Aldehyde dehydrogenase family
JGNPNPGP_01287 1.3e-210 pduQ C Iron-containing alcohol dehydrogenase
JGNPNPGP_01288 3.7e-221 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JGNPNPGP_01289 5.5e-56 pduU E BMC
JGNPNPGP_01290 1.9e-149 3.1.3.48 T Pfam:Y_phosphatase3C
JGNPNPGP_01291 1.5e-120 pgm1 3.1.3.73 G phosphoglycerate mutase
JGNPNPGP_01292 3.1e-93 P Cadmium resistance transporter
JGNPNPGP_01293 3e-72 eutP E Ethanolamine utilisation - propanediol utilisation
JGNPNPGP_01294 1e-78 fld C Flavodoxin
JGNPNPGP_01295 1.2e-157 XK27_04590 S NADPH-dependent FMN reductase
JGNPNPGP_01296 1.7e-102 cobO 2.5.1.17 S Cobalamin adenosyltransferase
JGNPNPGP_01297 9.6e-208 cobD 4.1.1.81 E Aminotransferase class I and II
JGNPNPGP_01298 1.8e-251 cbiA 6.3.5.11, 6.3.5.9 F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
JGNPNPGP_01299 2.8e-174 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
JGNPNPGP_01300 9.2e-124 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
JGNPNPGP_01301 6.6e-207 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
JGNPNPGP_01302 3.9e-110 cbiE 2.1.1.132, 2.1.1.289 H Tetrapyrrole (Corrin/Porphyrin) Methylases
JGNPNPGP_01303 4.1e-98 cbiT 2.1.1.132, 2.1.1.196 H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
JGNPNPGP_01304 1.8e-136 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
JGNPNPGP_01305 1.8e-195 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
JGNPNPGP_01306 5.7e-132 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H Tetrapyrrole (Corrin/Porphyrin) Methylases
JGNPNPGP_01307 2.8e-137 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H Precorrin-6x reductase CbiJ/CobK
JGNPNPGP_01308 2.8e-260 cobA 2.1.1.107, 4.2.1.75 H Tetrapyrrole (Corrin/Porphyrin) Methylases
JGNPNPGP_01309 8.9e-147 cbiK 4.99.1.3 H Cobalt chelatase (CbiK)
JGNPNPGP_01310 3e-125 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Tetrapyrrole (Corrin/Porphyrin) Methylases
JGNPNPGP_01311 2.4e-133 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
JGNPNPGP_01312 8.7e-53 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
JGNPNPGP_01313 4.4e-118 cbiQ P Cobalt transport protein
JGNPNPGP_01314 2e-149 cbiO 2.1.1.195 P part of an ABC transporter complex. Responsible for energy coupling to the transport system
JGNPNPGP_01315 2.8e-282 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
JGNPNPGP_01316 3.2e-80 cysG 1.3.1.76, 4.99.1.4 H Putative NAD(P)-binding
JGNPNPGP_01317 2.3e-237 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JGNPNPGP_01318 1.3e-168 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
JGNPNPGP_01319 6.9e-181 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
JGNPNPGP_01320 3.8e-251 hemL 5.4.3.8 H Aminotransferase class-III
JGNPNPGP_01321 1.6e-103 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Cobinamide kinase / cobinamide phosphate guanyltransferase
JGNPNPGP_01322 6.9e-136 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
JGNPNPGP_01323 5.4e-112 gpm 3.1.3.73, 5.4.2.12 G Belongs to the phosphoglycerate mutase family
JGNPNPGP_01324 5.3e-130 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
JGNPNPGP_01325 2.9e-193 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
JGNPNPGP_01326 2.5e-62 S Domain of unknown function (DUF4430)
JGNPNPGP_01327 6.4e-80 S ECF transporter, substrate-specific component
JGNPNPGP_01328 8.3e-190 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JGNPNPGP_01329 8.2e-310 lmrA V ABC transporter, ATP-binding protein
JGNPNPGP_01330 4.2e-248 yfiC V ABC transporter
JGNPNPGP_01331 5.2e-76 yfiC V ABC transporter
JGNPNPGP_01332 2.4e-283 pipD E Dipeptidase
JGNPNPGP_01333 6.1e-88 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JGNPNPGP_01334 4.3e-135 gntR K UbiC transcription regulator-associated domain protein
JGNPNPGP_01335 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
JGNPNPGP_01336 9.4e-245 yagE E amino acid
JGNPNPGP_01337 2.6e-140 aroD S Serine hydrolase (FSH1)
JGNPNPGP_01338 5.3e-240 brnQ U Component of the transport system for branched-chain amino acids
JGNPNPGP_01339 3.1e-167 GK ROK family
JGNPNPGP_01340 0.0 tetP J elongation factor G
JGNPNPGP_01341 5.1e-81 uspA T universal stress protein
JGNPNPGP_01342 5.1e-195 lplA 6.3.1.20 H Lipoate-protein ligase
JGNPNPGP_01343 7.1e-63
JGNPNPGP_01344 5.2e-14
JGNPNPGP_01345 3.7e-107
JGNPNPGP_01346 1.3e-133 V ABC transporter
JGNPNPGP_01347 1.8e-212 EGP Major facilitator Superfamily
JGNPNPGP_01348 1.3e-257 G PTS system Galactitol-specific IIC component
JGNPNPGP_01349 5.5e-178 1.6.5.5 C Zinc-binding dehydrogenase
JGNPNPGP_01350 2.6e-160
JGNPNPGP_01351 1e-72 K Transcriptional regulator
JGNPNPGP_01352 1.8e-189 D Alpha beta
JGNPNPGP_01353 2.2e-52 ypaA S Protein of unknown function (DUF1304)
JGNPNPGP_01354 1.8e-234 L transposase IS116 IS110 IS902 family protein
JGNPNPGP_01363 1.2e-55 L Transposase
JGNPNPGP_01366 3.4e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
JGNPNPGP_01367 7.2e-199 XK27_09615 S reductase
JGNPNPGP_01368 4.1e-101 nqr 1.5.1.36 S reductase
JGNPNPGP_01369 1.6e-268 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JGNPNPGP_01370 3.8e-182 K Transcriptional regulator, LacI family
JGNPNPGP_01371 4.7e-260 G Major Facilitator
JGNPNPGP_01372 8.1e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
JGNPNPGP_01373 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
JGNPNPGP_01374 2e-266 G Major Facilitator
JGNPNPGP_01375 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
JGNPNPGP_01376 1.2e-300 M domain protein
JGNPNPGP_01377 5.1e-268 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
JGNPNPGP_01378 8.1e-269 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
JGNPNPGP_01379 4.6e-70
JGNPNPGP_01380 1.1e-110 K Transcriptional regulator, TetR family
JGNPNPGP_01382 1.4e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JGNPNPGP_01383 6.8e-62
JGNPNPGP_01384 2.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JGNPNPGP_01385 3.8e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
JGNPNPGP_01386 7.1e-261 nox C NADH oxidase
JGNPNPGP_01387 3.9e-87 hmpT S ECF-type riboflavin transporter, S component
JGNPNPGP_01388 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
JGNPNPGP_01389 1.7e-167 yvgN C Aldo keto reductase
JGNPNPGP_01390 7.8e-137 puuD S peptidase C26
JGNPNPGP_01391 1.1e-258 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
JGNPNPGP_01392 3.1e-212 yfeO P Voltage gated chloride channel
JGNPNPGP_01393 4.2e-223 sptS 2.7.13.3 T Histidine kinase
JGNPNPGP_01394 1.5e-115 K response regulator
JGNPNPGP_01395 1.1e-86 2.7.6.5 T Region found in RelA / SpoT proteins
JGNPNPGP_01396 3.8e-71
JGNPNPGP_01397 1.6e-120 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
JGNPNPGP_01398 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
JGNPNPGP_01399 1.1e-256 malT G Major Facilitator
JGNPNPGP_01400 1.6e-208 phbA 2.3.1.9 I Belongs to the thiolase family
JGNPNPGP_01401 9.5e-172 malR K Transcriptional regulator, LacI family
JGNPNPGP_01402 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
JGNPNPGP_01403 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
JGNPNPGP_01404 7.7e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JGNPNPGP_01405 5.7e-106 wecD3 K PFAM GCN5-related N-acetyltransferase
JGNPNPGP_01407 0.0 clpL O associated with various cellular activities
JGNPNPGP_01408 2.7e-32
JGNPNPGP_01409 1.7e-218 patA 2.6.1.1 E Aminotransferase
JGNPNPGP_01410 3.7e-174 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JGNPNPGP_01411 4.2e-74 osmC O OsmC-like protein
JGNPNPGP_01413 5.3e-242 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
JGNPNPGP_01415 1.8e-136 K LytTr DNA-binding domain
JGNPNPGP_01416 5.4e-189 2.7.13.3 T GHKL domain
JGNPNPGP_01419 1.8e-230 S Putative peptidoglycan binding domain
JGNPNPGP_01420 4.6e-51 M NlpC P60 family protein
JGNPNPGP_01421 1.5e-38
JGNPNPGP_01423 1.6e-214 bacI V MacB-like periplasmic core domain
JGNPNPGP_01424 1.3e-128 V ABC transporter
JGNPNPGP_01425 2e-144 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JGNPNPGP_01426 3.7e-257 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
JGNPNPGP_01427 1.6e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JGNPNPGP_01428 2.1e-148 E Glyoxalase-like domain
JGNPNPGP_01429 7.5e-155 glcU U sugar transport
JGNPNPGP_01430 1.9e-225 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
JGNPNPGP_01431 1.9e-95 S reductase
JGNPNPGP_01433 4.7e-88 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JGNPNPGP_01434 1.1e-178 ABC-SBP S ABC transporter
JGNPNPGP_01435 1.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
JGNPNPGP_01436 4.1e-218 htrA 3.4.21.107 O serine protease
JGNPNPGP_01437 1.6e-154 vicX 3.1.26.11 S domain protein
JGNPNPGP_01438 4.2e-150 yycI S YycH protein
JGNPNPGP_01439 3.5e-249 yycH S YycH protein
JGNPNPGP_01440 0.0 vicK 2.7.13.3 T Histidine kinase
JGNPNPGP_01441 3.1e-130 K response regulator
JGNPNPGP_01443 1.2e-310 lmrA 3.6.3.44 V ABC transporter
JGNPNPGP_01444 8.1e-73 K helix_turn_helix multiple antibiotic resistance protein
JGNPNPGP_01446 9.3e-125 Z012_01130 S Fic/DOC family
JGNPNPGP_01447 4.3e-158 S Polyphosphate nucleotide phosphotransferase, PPK2 family
JGNPNPGP_01448 9.4e-58
JGNPNPGP_01449 2.6e-206 yttB EGP Major facilitator Superfamily
JGNPNPGP_01450 5.3e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
JGNPNPGP_01451 2e-74 rplI J Binds to the 23S rRNA
JGNPNPGP_01452 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
JGNPNPGP_01453 4.7e-102 deoR K sugar-binding domain protein
JGNPNPGP_01454 2.7e-96 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JGNPNPGP_01455 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JGNPNPGP_01456 7.5e-79 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
JGNPNPGP_01457 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
JGNPNPGP_01458 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JGNPNPGP_01459 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JGNPNPGP_01460 1.1e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JGNPNPGP_01461 1.7e-34 yaaA S S4 domain protein YaaA
JGNPNPGP_01462 1.1e-125 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
JGNPNPGP_01463 8.5e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
JGNPNPGP_01464 2.2e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JGNPNPGP_01465 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
JGNPNPGP_01466 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
JGNPNPGP_01467 1e-129 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JGNPNPGP_01468 2.1e-132 jag S R3H domain protein
JGNPNPGP_01469 1.4e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JGNPNPGP_01470 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
JGNPNPGP_01471 0.0 asnB 6.3.5.4 E Asparagine synthase
JGNPNPGP_01472 6e-296 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JGNPNPGP_01473 6.4e-248 yxbA 6.3.1.12 S ATP-grasp enzyme
JGNPNPGP_01474 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
JGNPNPGP_01475 4e-92 2.3.1.183 M Acetyltransferase GNAT family
JGNPNPGP_01476 7e-161 S reductase
JGNPNPGP_01478 3.9e-147 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JGNPNPGP_01479 7.2e-126 S Alpha/beta hydrolase of unknown function (DUF915)
JGNPNPGP_01480 1.9e-297 S amidohydrolase
JGNPNPGP_01481 5.6e-46 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JGNPNPGP_01482 1.7e-54 adaA 3.2.2.21 K Metal binding domain of Ada
JGNPNPGP_01483 1.1e-259 K Aminotransferase class I and II
JGNPNPGP_01484 4.8e-120 azlC E azaleucine resistance protein AzlC
JGNPNPGP_01485 3.2e-50 azlD E Branched-chain amino acid transport
JGNPNPGP_01486 4.5e-120 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
JGNPNPGP_01487 6e-49 K Helix-turn-helix domain
JGNPNPGP_01488 4.4e-69 S SnoaL-like polyketide cyclase
JGNPNPGP_01489 2.6e-116 1.3.1.9 S Nitronate monooxygenase
JGNPNPGP_01490 3e-127 rocF 3.5.3.1, 3.5.3.11 E Arginase family
JGNPNPGP_01491 9.1e-107 K Bacterial regulatory proteins, tetR family
JGNPNPGP_01492 2.3e-188 ybhR V ABC transporter
JGNPNPGP_01493 2.7e-126 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
JGNPNPGP_01494 1.2e-117 S GyrI-like small molecule binding domain
JGNPNPGP_01495 1.8e-124 yhiD S MgtC family
JGNPNPGP_01496 1.8e-119 K Transcriptional regulator
JGNPNPGP_01497 8.9e-109 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JGNPNPGP_01498 7e-100 S Alpha/beta hydrolase of unknown function (DUF915)
JGNPNPGP_01499 4.9e-39 maa S maltose O-acetyltransferase activity
JGNPNPGP_01500 3.2e-114 S Belongs to the short-chain dehydrogenases reductases (SDR) family
JGNPNPGP_01501 6.7e-179 S Hydrolases of the alpha beta superfamily
JGNPNPGP_01502 1.7e-62 qor 1.6.5.5 C Zinc-binding dehydrogenase
JGNPNPGP_01503 1.2e-45 C Flavodoxin
JGNPNPGP_01504 7.6e-119 P FAD-binding domain
JGNPNPGP_01505 2.4e-89 GM NAD(P)H-binding
JGNPNPGP_01506 1.6e-94 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
JGNPNPGP_01507 1.4e-195 V Beta-lactamase
JGNPNPGP_01508 4.8e-54 yphI 1.14.99.57 S Antibiotic biosynthesis monooxygenase
JGNPNPGP_01509 9.1e-89 XK27_08850 J Aminoacyl-tRNA editing domain
JGNPNPGP_01510 1.4e-19 relB L Addiction module antitoxin, RelB DinJ family
JGNPNPGP_01511 4e-24
JGNPNPGP_01512 5.9e-119 K LytTr DNA-binding domain
JGNPNPGP_01513 3.6e-190 2.7.13.3 T GHKL domain
JGNPNPGP_01518 5.6e-121 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
JGNPNPGP_01519 7.6e-68 mleP3 S Membrane transport protein
JGNPNPGP_01520 8.7e-106 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JGNPNPGP_01521 2.2e-50 K transcriptional
JGNPNPGP_01522 8.1e-120 T Transcriptional regulatory protein, C terminal
JGNPNPGP_01523 3.1e-232 T GHKL domain
JGNPNPGP_01524 2.1e-93 S Peptidase propeptide and YPEB domain
JGNPNPGP_01525 7e-133 K Transcriptional regulator
JGNPNPGP_01526 9.7e-125 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
JGNPNPGP_01527 1.5e-219 4.4.1.8 E Aminotransferase, class I
JGNPNPGP_01528 4.8e-98 M Protein of unknown function (DUF3737)
JGNPNPGP_01529 3.3e-55 yphJ 4.1.1.44 S decarboxylase
JGNPNPGP_01530 1.5e-166 S Oxidoreductase, aldo keto reductase family protein
JGNPNPGP_01531 1.3e-84 C Flavodoxin
JGNPNPGP_01532 9.4e-17
JGNPNPGP_01533 4.5e-147 K Transcriptional regulator
JGNPNPGP_01534 3.1e-87 lacA S transferase hexapeptide repeat
JGNPNPGP_01535 2.1e-134 S Hydrolases of the alpha beta superfamily
JGNPNPGP_01536 2.7e-152 S Alpha beta hydrolase
JGNPNPGP_01539 7.5e-115 nreC K PFAM regulatory protein LuxR
JGNPNPGP_01540 6e-38 S Cytochrome B5
JGNPNPGP_01541 2.2e-156 yitU 3.1.3.104 S hydrolase
JGNPNPGP_01542 5e-262 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
JGNPNPGP_01543 2e-147 f42a O Band 7 protein
JGNPNPGP_01544 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
JGNPNPGP_01545 3.3e-127 lytT K response regulator receiver
JGNPNPGP_01546 1.9e-66 lrgA S LrgA family
JGNPNPGP_01547 1.3e-123 lrgB M LrgB-like family
JGNPNPGP_01548 1.6e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
JGNPNPGP_01549 2.2e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
JGNPNPGP_01550 9.7e-186 galR K Periplasmic binding protein-like domain
JGNPNPGP_01551 0.0 rafA 3.2.1.22 G alpha-galactosidase
JGNPNPGP_01552 1.9e-89 S Protein of unknown function (DUF1440)
JGNPNPGP_01553 3.8e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
JGNPNPGP_01554 4.2e-214 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
JGNPNPGP_01555 1.9e-162 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
JGNPNPGP_01556 3.9e-173 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
JGNPNPGP_01557 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
JGNPNPGP_01558 1.9e-84 ypmB S Protein conserved in bacteria
JGNPNPGP_01559 2.1e-123 dnaD L DnaD domain protein
JGNPNPGP_01560 1.5e-158 EG EamA-like transporter family
JGNPNPGP_01561 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
JGNPNPGP_01562 1.2e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
JGNPNPGP_01563 4.1e-101 ypsA S Belongs to the UPF0398 family
JGNPNPGP_01564 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
JGNPNPGP_01565 2.2e-84 F Belongs to the NrdI family
JGNPNPGP_01566 1e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
JGNPNPGP_01567 5.3e-71 rnhA 3.1.26.4 L Ribonuclease HI
JGNPNPGP_01568 1.5e-65 esbA S Family of unknown function (DUF5322)
JGNPNPGP_01569 1.7e-73 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JGNPNPGP_01570 1.1e-175 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JGNPNPGP_01571 4.3e-208 carA 6.3.5.5 F Belongs to the CarA family
JGNPNPGP_01572 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
JGNPNPGP_01573 0.0 FbpA K Fibronectin-binding protein
JGNPNPGP_01574 5.5e-161 degV S EDD domain protein, DegV family
JGNPNPGP_01575 1.8e-92
JGNPNPGP_01576 6.6e-119 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
JGNPNPGP_01577 4.5e-160 gspA M family 8
JGNPNPGP_01578 4.4e-160 S Alpha beta hydrolase
JGNPNPGP_01579 2.4e-95 K Acetyltransferase (GNAT) domain
JGNPNPGP_01580 1.3e-241 XK27_08635 S UPF0210 protein
JGNPNPGP_01581 2.1e-39 gcvR T Belongs to the UPF0237 family
JGNPNPGP_01582 3.6e-168 1.1.1.346 C Aldo keto reductase
JGNPNPGP_01583 6e-95 exuR K Periplasmic binding protein domain
JGNPNPGP_01584 4.6e-221 yjmB G MFS/sugar transport protein
JGNPNPGP_01585 2.1e-229 uxaC 5.3.1.12 G glucuronate isomerase
JGNPNPGP_01586 2.5e-95 S module of peptide synthetase
JGNPNPGP_01588 1.8e-150 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
JGNPNPGP_01589 2.1e-128 uxaA 4.2.1.7, 4.4.1.24 G Altronate
JGNPNPGP_01591 1.8e-68 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
JGNPNPGP_01592 1.5e-166 uxaA 4.2.1.7, 4.4.1.24 G Altronate
JGNPNPGP_01593 4.3e-125 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
JGNPNPGP_01594 1.9e-52 kdgR K FCD
JGNPNPGP_01595 2.5e-212 mtlD 1.1.1.17, 1.1.1.57 G Mannitol dehydrogenase C-terminal domain
JGNPNPGP_01596 4e-182 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
JGNPNPGP_01597 6.2e-216 uxuT G MFS/sugar transport protein
JGNPNPGP_01598 5.3e-217 uxaC 5.3.1.12 G glucuronate isomerase
JGNPNPGP_01599 1.4e-134 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
JGNPNPGP_01600 9.3e-131 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JGNPNPGP_01601 1.9e-69 K Bacterial transcriptional regulator
JGNPNPGP_01602 7.9e-160 K LysR substrate binding domain protein
JGNPNPGP_01603 6.7e-81 C Flavodoxin
JGNPNPGP_01604 1.1e-79 yphH S Cupin domain
JGNPNPGP_01605 5.8e-74 yeaL S UPF0756 membrane protein
JGNPNPGP_01606 4.3e-245 EGP Major facilitator Superfamily
JGNPNPGP_01607 7.2e-74 copY K Copper transport repressor CopY TcrY
JGNPNPGP_01608 8.5e-246 yhdP S Transporter associated domain
JGNPNPGP_01609 0.0 ubiB S ABC1 family
JGNPNPGP_01610 5.6e-144 S DUF218 domain
JGNPNPGP_01611 8.3e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JGNPNPGP_01612 4.9e-58 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JGNPNPGP_01613 8.5e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JGNPNPGP_01614 0.0 uvrA3 L excinuclease ABC, A subunit
JGNPNPGP_01615 1e-122 S SNARE associated Golgi protein
JGNPNPGP_01616 7.9e-230 N Uncharacterized conserved protein (DUF2075)
JGNPNPGP_01617 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JGNPNPGP_01619 1e-254 yifK E Amino acid permease
JGNPNPGP_01620 1.1e-158 endA V DNA/RNA non-specific endonuclease
JGNPNPGP_01621 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JGNPNPGP_01622 6e-42 ybaN S Protein of unknown function (DUF454)
JGNPNPGP_01623 5.3e-72 S Protein of unknown function (DUF3290)
JGNPNPGP_01624 1.2e-114 yviA S Protein of unknown function (DUF421)
JGNPNPGP_01625 5.2e-164 S Alpha/beta hydrolase of unknown function (DUF915)
JGNPNPGP_01626 3.5e-18
JGNPNPGP_01627 1.1e-89 ntd 2.4.2.6 F Nucleoside
JGNPNPGP_01628 1.3e-151 3.1.3.102, 3.1.3.104 S hydrolase
JGNPNPGP_01629 5.2e-49 yrvD S Pfam:DUF1049
JGNPNPGP_01631 1.5e-43 L Belongs to the 'phage' integrase family
JGNPNPGP_01632 2.5e-08
JGNPNPGP_01634 1.8e-226 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
JGNPNPGP_01635 7.6e-23 S Phage derived protein Gp49-like (DUF891)
JGNPNPGP_01636 8.5e-20 K Helix-turn-helix XRE-family like proteins
JGNPNPGP_01637 2.6e-163 I alpha/beta hydrolase fold
JGNPNPGP_01638 1.8e-113 frnE Q DSBA-like thioredoxin domain
JGNPNPGP_01639 6.2e-55
JGNPNPGP_01648 6e-132 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
JGNPNPGP_01649 1.6e-135 accA 2.1.3.15, 6.4.1.2 I alpha subunit
JGNPNPGP_01650 2.3e-140 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JGNPNPGP_01651 2.6e-258 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
JGNPNPGP_01652 1.5e-74 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
JGNPNPGP_01653 4.9e-73 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
JGNPNPGP_01654 1.6e-222 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
JGNPNPGP_01655 5.6e-127 IQ reductase
JGNPNPGP_01656 9.1e-154 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
JGNPNPGP_01657 8.5e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
JGNPNPGP_01658 3.8e-171 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JGNPNPGP_01659 4.2e-77 marR K Transcriptional regulator, MarR family
JGNPNPGP_01660 4.3e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
JGNPNPGP_01662 4.6e-202 xerS L Belongs to the 'phage' integrase family
JGNPNPGP_01663 2.2e-179 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
JGNPNPGP_01664 5.6e-82 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
JGNPNPGP_01665 6.1e-157 rssA S Phospholipase, patatin family
JGNPNPGP_01666 9.4e-118 L Integrase
JGNPNPGP_01667 1.5e-153 EG EamA-like transporter family
JGNPNPGP_01668 2.5e-129 narI 1.7.5.1 C Nitrate reductase
JGNPNPGP_01669 6.9e-96 narJ C nitrate reductase molybdenum cofactor assembly chaperone
JGNPNPGP_01670 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
JGNPNPGP_01671 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JGNPNPGP_01672 4.8e-185 moeB 2.7.7.73, 2.7.7.80 H ThiF family
JGNPNPGP_01673 1.8e-84 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
JGNPNPGP_01674 1.8e-223 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
JGNPNPGP_01675 7.5e-75 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
JGNPNPGP_01676 1.2e-97 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
JGNPNPGP_01677 1.4e-41
JGNPNPGP_01678 4.5e-186 comP 2.7.13.3 F Sensor histidine kinase
JGNPNPGP_01679 9.8e-115 nreC K PFAM regulatory protein LuxR
JGNPNPGP_01680 4.6e-18
JGNPNPGP_01681 1.3e-171
JGNPNPGP_01682 9.1e-143 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
JGNPNPGP_01683 1.2e-216 narK P Transporter, major facilitator family protein
JGNPNPGP_01684 3.9e-32 moaD 2.8.1.12 H ThiS family
JGNPNPGP_01685 3.5e-62 moaE 2.8.1.12 H MoaE protein
JGNPNPGP_01686 1.4e-75 S Flavodoxin
JGNPNPGP_01687 7.8e-129 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JGNPNPGP_01688 7.3e-133 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
JGNPNPGP_01689 4.8e-177 fecB P Periplasmic binding protein
JGNPNPGP_01690 1.5e-175
JGNPNPGP_01691 1.9e-74
JGNPNPGP_01692 6.9e-13 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
JGNPNPGP_01693 2.9e-87 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
JGNPNPGP_01694 0.0 S SEC-C Motif Domain Protein
JGNPNPGP_01695 1.2e-51
JGNPNPGP_01696 1.7e-140 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JGNPNPGP_01697 3.4e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
JGNPNPGP_01698 7.2e-118 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
JGNPNPGP_01699 9.4e-231 clcA_2 P Chloride transporter, ClC family
JGNPNPGP_01700 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
JGNPNPGP_01701 9e-113 lssY 3.6.1.27 I Acid phosphatase homologues
JGNPNPGP_01702 5.1e-07 fhaB M Rib/alpha-like repeat
JGNPNPGP_01703 3.9e-12
JGNPNPGP_01704 3.8e-218 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
JGNPNPGP_01705 6.9e-297 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JGNPNPGP_01706 3.1e-264 glnA 6.3.1.2 E glutamine synthetase
JGNPNPGP_01707 3.3e-177 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JGNPNPGP_01708 5.9e-22 S Protein of unknown function (DUF3042)
JGNPNPGP_01709 7.2e-71 yqhL P Rhodanese-like protein
JGNPNPGP_01710 1.5e-183 glk 2.7.1.2 G Glucokinase
JGNPNPGP_01711 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
JGNPNPGP_01712 2.4e-113 gluP 3.4.21.105 S Peptidase, S54 family
JGNPNPGP_01713 3.4e-100 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JGNPNPGP_01714 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
JGNPNPGP_01715 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
JGNPNPGP_01716 0.0 S membrane
JGNPNPGP_01717 2.6e-70 yneR S Belongs to the HesB IscA family
JGNPNPGP_01718 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
JGNPNPGP_01719 1.4e-116 udk 2.7.1.48 F Cytidine monophosphokinase
JGNPNPGP_01720 2.8e-106 rlpA M PFAM NLP P60 protein
JGNPNPGP_01721 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JGNPNPGP_01722 2.3e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JGNPNPGP_01723 1.1e-58 yodB K Transcriptional regulator, HxlR family
JGNPNPGP_01724 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
JGNPNPGP_01725 8.3e-145 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JGNPNPGP_01726 1.3e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
JGNPNPGP_01727 1e-168 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JGNPNPGP_01728 3.9e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
JGNPNPGP_01729 8.9e-232 V MatE
JGNPNPGP_01730 1.7e-182 yjeM E Amino Acid
JGNPNPGP_01731 1e-37 yjeM E Amino Acid
JGNPNPGP_01732 5.4e-278 arlS 2.7.13.3 T Histidine kinase
JGNPNPGP_01733 1.5e-121 K response regulator
JGNPNPGP_01734 7.3e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
JGNPNPGP_01735 2.9e-99 yceD S Uncharacterized ACR, COG1399
JGNPNPGP_01736 5.3e-209 ylbM S Belongs to the UPF0348 family
JGNPNPGP_01737 1.1e-138 yqeM Q Methyltransferase
JGNPNPGP_01738 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
JGNPNPGP_01739 3e-113 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
JGNPNPGP_01740 9.6e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JGNPNPGP_01741 1.9e-47 yhbY J RNA-binding protein
JGNPNPGP_01742 2.1e-218 yqeH S Ribosome biogenesis GTPase YqeH
JGNPNPGP_01743 2.2e-96 yqeG S HAD phosphatase, family IIIA
JGNPNPGP_01744 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JGNPNPGP_01745 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
JGNPNPGP_01746 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JGNPNPGP_01747 1.8e-170 dnaI L Primosomal protein DnaI
JGNPNPGP_01748 2.3e-203 dnaB L replication initiation and membrane attachment
JGNPNPGP_01749 4.3e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JGNPNPGP_01750 3.3e-101 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JGNPNPGP_01751 1.1e-158 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
JGNPNPGP_01752 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JGNPNPGP_01753 1.2e-118 yoaK S Protein of unknown function (DUF1275)
JGNPNPGP_01754 1.4e-119 ybhL S Belongs to the BI1 family
JGNPNPGP_01755 2.9e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
JGNPNPGP_01756 7.2e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JGNPNPGP_01757 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
JGNPNPGP_01758 7.5e-58 ytzB S Small secreted protein
JGNPNPGP_01759 2.2e-168 glsA 3.5.1.2 E Belongs to the glutaminase family
JGNPNPGP_01760 2.7e-185 iolS C Aldo keto reductase
JGNPNPGP_01761 5.1e-268 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
JGNPNPGP_01762 0.0 2.7.7.7, 3.4.21.110 D Leucine-rich repeat (LRR) protein
JGNPNPGP_01763 1.2e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
JGNPNPGP_01764 3.5e-219 ecsB U ABC transporter
JGNPNPGP_01765 1.8e-136 ecsA V ABC transporter, ATP-binding protein
JGNPNPGP_01766 8.3e-78 hit FG histidine triad
JGNPNPGP_01768 3.4e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
JGNPNPGP_01769 0.0 L AAA domain
JGNPNPGP_01770 2.6e-222 yhaO L Ser Thr phosphatase family protein
JGNPNPGP_01771 1.7e-42 yheA S Belongs to the UPF0342 family
JGNPNPGP_01772 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JGNPNPGP_01773 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
JGNPNPGP_01774 2.1e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
JGNPNPGP_01775 7.9e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
JGNPNPGP_01776 1e-224 L Transposase
JGNPNPGP_01778 3.3e-40
JGNPNPGP_01779 3e-43
JGNPNPGP_01780 8.1e-213 folP 2.5.1.15 H dihydropteroate synthase
JGNPNPGP_01781 1.1e-104 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
JGNPNPGP_01782 1e-221 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
JGNPNPGP_01783 6.2e-105 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
JGNPNPGP_01784 4.1e-92 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
JGNPNPGP_01785 2e-55 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JGNPNPGP_01786 2e-70
JGNPNPGP_01787 5.1e-142 S Domain of unknown function DUF1829
JGNPNPGP_01788 2e-24
JGNPNPGP_01789 4e-16
JGNPNPGP_01790 4.9e-10 M LysM domain
JGNPNPGP_01793 1.9e-43
JGNPNPGP_01794 4.1e-116 S CAAX protease self-immunity
JGNPNPGP_01795 5.3e-31
JGNPNPGP_01796 2e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JGNPNPGP_01797 1.1e-184 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
JGNPNPGP_01798 4.2e-112
JGNPNPGP_01799 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
JGNPNPGP_01800 8.8e-15 lmrB EGP Major facilitator Superfamily
JGNPNPGP_01801 6.9e-108 lmrB EGP Major facilitator Superfamily
JGNPNPGP_01802 9.2e-24 K Transcriptional regulator
JGNPNPGP_01803 2.3e-174 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
JGNPNPGP_01804 1.9e-86 uspA T Belongs to the universal stress protein A family
JGNPNPGP_01805 4.8e-276 pepV 3.5.1.18 E dipeptidase PepV
JGNPNPGP_01806 2.3e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JGNPNPGP_01807 8.3e-304 ytgP S Polysaccharide biosynthesis protein
JGNPNPGP_01808 7.6e-42
JGNPNPGP_01809 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
JGNPNPGP_01810 1.9e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JGNPNPGP_01811 3e-93 tag 3.2.2.20 L glycosylase
JGNPNPGP_01812 3e-257 EGP Major facilitator Superfamily
JGNPNPGP_01813 1.1e-83 perR P Belongs to the Fur family
JGNPNPGP_01814 1e-227 cycA E Amino acid permease
JGNPNPGP_01815 6.3e-102 V VanZ like family
JGNPNPGP_01816 1e-23
JGNPNPGP_01817 7.9e-83 S Short repeat of unknown function (DUF308)
JGNPNPGP_01819 1.8e-36
JGNPNPGP_01820 2.2e-79 L Integrase
JGNPNPGP_01821 1.8e-122 res_1 3.1.21.5 S Type III restriction
JGNPNPGP_01822 1.5e-155 sthIM 2.1.1.72 L DNA methylase
JGNPNPGP_01823 1.2e-185 L Transposase
JGNPNPGP_01824 7.5e-19 L PFAM transposase IS200-family protein
JGNPNPGP_01825 1.7e-70 S Psort location Cytoplasmic, score
JGNPNPGP_01826 8.7e-276 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
JGNPNPGP_01827 4.5e-76 hsp O Belongs to the small heat shock protein (HSP20) family
JGNPNPGP_01828 1.4e-153 yeaE S Aldo keto
JGNPNPGP_01829 5.3e-237 preA 1.3.1.1 C 4Fe-4S dicluster domain
JGNPNPGP_01830 9.5e-236 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
JGNPNPGP_01831 7.8e-148 xth 3.1.11.2 L exodeoxyribonuclease III
JGNPNPGP_01832 4.7e-241 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
JGNPNPGP_01833 9.3e-130 IQ Dehydrogenase reductase
JGNPNPGP_01834 1.4e-36
JGNPNPGP_01835 6.3e-114 ywnB S NAD(P)H-binding
JGNPNPGP_01836 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
JGNPNPGP_01837 3e-254 nhaC C Na H antiporter NhaC
JGNPNPGP_01838 2e-183 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JGNPNPGP_01840 8.2e-99 ydeN S Serine hydrolase
JGNPNPGP_01841 4.5e-62 psiE S Phosphate-starvation-inducible E
JGNPNPGP_01842 5e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
JGNPNPGP_01844 7e-178 S Aldo keto reductase
JGNPNPGP_01845 7.1e-81 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
JGNPNPGP_01846 0.0 L Helicase C-terminal domain protein
JGNPNPGP_01848 3.6e-244 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
JGNPNPGP_01849 1.8e-53 S Sugar efflux transporter for intercellular exchange
JGNPNPGP_01850 9.2e-127
JGNPNPGP_01851 1.2e-124 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
JGNPNPGP_01852 0.0 cadA P P-type ATPase
JGNPNPGP_01853 2.5e-225 5.4.2.7 G Metalloenzyme superfamily
JGNPNPGP_01855 3.6e-157 1.6.5.2 GM NAD(P)H-binding
JGNPNPGP_01856 2e-74 K Transcriptional regulator
JGNPNPGP_01857 7.8e-163 proX M ABC transporter, substrate-binding protein, QAT family
JGNPNPGP_01858 2.4e-108 proWZ P ABC transporter permease
JGNPNPGP_01859 2.5e-141 proV E ABC transporter, ATP-binding protein
JGNPNPGP_01860 6.4e-103 proW P ABC transporter, permease protein
JGNPNPGP_01861 1.8e-77 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
JGNPNPGP_01862 5.4e-253 clcA P chloride
JGNPNPGP_01863 5.7e-219 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
JGNPNPGP_01864 3.1e-103 metI P ABC transporter permease
JGNPNPGP_01865 2.1e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JGNPNPGP_01866 2.5e-155 metQ1 P Belongs to the nlpA lipoprotein family
JGNPNPGP_01867 2.3e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
JGNPNPGP_01868 8.3e-221 norA EGP Major facilitator Superfamily
JGNPNPGP_01869 1.9e-43 1.3.5.4 S FMN binding
JGNPNPGP_01870 2.4e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JGNPNPGP_01871 1.8e-265 yfnA E amino acid
JGNPNPGP_01872 4.5e-255 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JGNPNPGP_01874 9.1e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
JGNPNPGP_01875 0.0 helD 3.6.4.12 L DNA helicase
JGNPNPGP_01876 2.2e-81 ndk 2.7.4.6 F Belongs to the NDK family
JGNPNPGP_01877 3.8e-184 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
JGNPNPGP_01878 2.9e-190 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
JGNPNPGP_01879 6e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
JGNPNPGP_01880 8.2e-227 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
JGNPNPGP_01881 5.9e-177
JGNPNPGP_01882 1.2e-129 cobB K SIR2 family
JGNPNPGP_01884 1.5e-160 yunF F Protein of unknown function DUF72
JGNPNPGP_01885 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JGNPNPGP_01886 1.8e-153 tatD L hydrolase, TatD family
JGNPNPGP_01887 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JGNPNPGP_01888 1.5e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
JGNPNPGP_01889 6.8e-37 veg S Biofilm formation stimulator VEG
JGNPNPGP_01890 3.1e-161 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JGNPNPGP_01891 5.3e-167 znuA P Belongs to the bacterial solute-binding protein 9 family
JGNPNPGP_01892 7.7e-123 fhuC P ABC transporter
JGNPNPGP_01893 8e-127 znuB U ABC 3 transport family
JGNPNPGP_01894 6.9e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
JGNPNPGP_01895 7.5e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JGNPNPGP_01896 5.5e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JGNPNPGP_01897 1.2e-49
JGNPNPGP_01898 8.7e-203 rarA L recombination factor protein RarA
JGNPNPGP_01899 1.7e-148 yxeH S hydrolase
JGNPNPGP_01900 1.9e-269 ywfO S HD domain protein
JGNPNPGP_01901 2.3e-153 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
JGNPNPGP_01902 2.7e-67 ywiB S Domain of unknown function (DUF1934)
JGNPNPGP_01903 8.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
JGNPNPGP_01904 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
JGNPNPGP_01905 1.4e-237 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JGNPNPGP_01906 4.6e-41 rpmE2 J Ribosomal protein L31
JGNPNPGP_01907 2.4e-237 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JGNPNPGP_01908 6.7e-167 S Alpha/beta hydrolase of unknown function (DUF915)
JGNPNPGP_01909 6.6e-125 srtA 3.4.22.70 M sortase family
JGNPNPGP_01910 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
JGNPNPGP_01911 2.1e-159 3.2.1.55 GH51 G Right handed beta helix region
JGNPNPGP_01912 5.8e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
JGNPNPGP_01913 1.2e-163 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
JGNPNPGP_01914 1.7e-119 pgm3 G Belongs to the phosphoglycerate mutase family
JGNPNPGP_01915 5.2e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JGNPNPGP_01916 7e-93 lemA S LemA family
JGNPNPGP_01917 5.8e-158 htpX O Belongs to the peptidase M48B family
JGNPNPGP_01918 1.4e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
JGNPNPGP_01919 1.4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
JGNPNPGP_01920 0.0 sprD D Domain of Unknown Function (DUF1542)
JGNPNPGP_01921 2e-166 glsA 3.5.1.2 E Belongs to the glutaminase family
JGNPNPGP_01924 5.3e-22 K Helix-turn-helix domain
JGNPNPGP_01925 5.8e-23 D nuclear chromosome segregation
JGNPNPGP_01929 3.4e-58 S Plasmid replication protein
JGNPNPGP_01930 1.1e-14
JGNPNPGP_01931 3.9e-133 L Belongs to the 'phage' integrase family
JGNPNPGP_01932 2.2e-14 K Cro/C1-type HTH DNA-binding domain
JGNPNPGP_01934 1.8e-18
JGNPNPGP_01935 1.3e-263 dtpT U amino acid peptide transporter
JGNPNPGP_01936 3.7e-151 yjjH S Calcineurin-like phosphoesterase
JGNPNPGP_01939 6.9e-113
JGNPNPGP_01940 5e-249 EGP Major facilitator Superfamily
JGNPNPGP_01941 6.1e-299 aspT P Predicted Permease Membrane Region
JGNPNPGP_01942 2.2e-131 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
JGNPNPGP_01943 2.4e-127 gntR1 K UbiC transcription regulator-associated domain protein
JGNPNPGP_01944 2.5e-283 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JGNPNPGP_01945 1.5e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
JGNPNPGP_01946 0.0 yhgF K Tex-like protein N-terminal domain protein
JGNPNPGP_01947 8.1e-84 ydcK S Belongs to the SprT family
JGNPNPGP_01949 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
JGNPNPGP_01950 2.4e-186 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
JGNPNPGP_01951 0.0 S Bacterial membrane protein, YfhO
JGNPNPGP_01952 1.2e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JGNPNPGP_01953 5.4e-169 I alpha/beta hydrolase fold
JGNPNPGP_01954 8.5e-215 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
JGNPNPGP_01955 2.4e-119 tcyB E ABC transporter
JGNPNPGP_01956 9.8e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
JGNPNPGP_01957 6.2e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
JGNPNPGP_01958 1.7e-267 pepC 3.4.22.40 E Peptidase C1-like family
JGNPNPGP_01959 2.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JGNPNPGP_01960 1.1e-49 HA62_12640 S GCN5-related N-acetyl-transferase
JGNPNPGP_01961 7.3e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
JGNPNPGP_01962 1.6e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JGNPNPGP_01963 1.7e-207 yacL S domain protein
JGNPNPGP_01964 2.2e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
JGNPNPGP_01965 7.2e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JGNPNPGP_01966 6.1e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JGNPNPGP_01967 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
JGNPNPGP_01968 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
JGNPNPGP_01969 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
JGNPNPGP_01970 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JGNPNPGP_01971 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
JGNPNPGP_01972 7e-228 aadAT EK Aminotransferase, class I
JGNPNPGP_01974 1.2e-244 M Glycosyl transferase family group 2
JGNPNPGP_01975 4.3e-211 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
JGNPNPGP_01976 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JGNPNPGP_01977 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
JGNPNPGP_01978 7.7e-48
JGNPNPGP_01980 5.9e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
JGNPNPGP_01981 2.6e-55 K transcriptional regulator PadR family
JGNPNPGP_01982 1.3e-71 XK27_06920 S Protein of unknown function (DUF1700)
JGNPNPGP_01983 1.7e-131 S Putative adhesin
JGNPNPGP_01984 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
JGNPNPGP_01985 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JGNPNPGP_01986 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JGNPNPGP_01987 3.4e-35 nrdH O Glutaredoxin
JGNPNPGP_01988 2.9e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
JGNPNPGP_01989 1.7e-281 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JGNPNPGP_01990 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JGNPNPGP_01991 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JGNPNPGP_01992 9.7e-39 S Protein of unknown function (DUF2508)
JGNPNPGP_01993 1.5e-115 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JGNPNPGP_01994 7.6e-52 yaaQ S Cyclic-di-AMP receptor
JGNPNPGP_01995 1.8e-184 holB 2.7.7.7 L DNA polymerase III
JGNPNPGP_01996 5.9e-58 yabA L Involved in initiation control of chromosome replication
JGNPNPGP_01997 2.1e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JGNPNPGP_01998 5.6e-138 fat 3.1.2.21 I Acyl-ACP thioesterase
JGNPNPGP_01999 1.1e-281 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
JGNPNPGP_02000 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JGNPNPGP_02001 3.3e-175 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
JGNPNPGP_02002 9.4e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
JGNPNPGP_02003 1.5e-127 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
JGNPNPGP_02004 1.5e-103 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
JGNPNPGP_02005 1.2e-196 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JGNPNPGP_02006 7.2e-133 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JGNPNPGP_02007 1.5e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JGNPNPGP_02008 3.2e-136 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JGNPNPGP_02009 3.3e-118 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
JGNPNPGP_02010 3.7e-229 mtnE 2.6.1.83 E Aminotransferase
JGNPNPGP_02011 2.8e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JGNPNPGP_02012 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JGNPNPGP_02014 1.2e-163 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
JGNPNPGP_02015 1.4e-117 S Domain of unknown function (DUF4811)
JGNPNPGP_02016 9.4e-270 lmrB EGP Major facilitator Superfamily
JGNPNPGP_02017 3.4e-74 merR K MerR HTH family regulatory protein
JGNPNPGP_02018 1.1e-53
JGNPNPGP_02019 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JGNPNPGP_02020 1.7e-218 S CAAX protease self-immunity
JGNPNPGP_02021 1.4e-108 glnP P ABC transporter permease
JGNPNPGP_02022 1.6e-109 gluC P ABC transporter permease
JGNPNPGP_02023 1.7e-151 glnH ET ABC transporter
JGNPNPGP_02024 6.9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
JGNPNPGP_02025 2.7e-82 usp1 T Belongs to the universal stress protein A family
JGNPNPGP_02026 7.6e-110 S VIT family
JGNPNPGP_02027 5e-117 S membrane
JGNPNPGP_02028 7.7e-166 czcD P cation diffusion facilitator family transporter
JGNPNPGP_02029 4.1e-124 sirR K iron dependent repressor
JGNPNPGP_02030 1e-30 cspC K Cold shock protein
JGNPNPGP_02031 1.4e-128 thrE S Putative threonine/serine exporter
JGNPNPGP_02032 2.1e-82 S Threonine/Serine exporter, ThrE
JGNPNPGP_02033 3e-119 lssY 3.6.1.27 I phosphatase
JGNPNPGP_02034 2.3e-09 2.3.1.128 J Acetyltransferase (GNAT) domain
JGNPNPGP_02035 2.3e-276 lysP E amino acid
JGNPNPGP_02036 2.8e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
JGNPNPGP_02042 1e-11
JGNPNPGP_02043 4.8e-179 S Hydrolases of the alpha beta superfamily
JGNPNPGP_02044 3.6e-196 adhP 1.1.1.1 C alcohol dehydrogenase
JGNPNPGP_02045 3.4e-77 ctsR K Belongs to the CtsR family
JGNPNPGP_02046 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
JGNPNPGP_02047 1e-110 K Bacterial regulatory proteins, tetR family
JGNPNPGP_02048 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JGNPNPGP_02049 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JGNPNPGP_02050 1.8e-199 ykiI
JGNPNPGP_02051 5.2e-119 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
JGNPNPGP_02052 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JGNPNPGP_02053 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
JGNPNPGP_02054 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JGNPNPGP_02055 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
JGNPNPGP_02056 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JGNPNPGP_02057 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
JGNPNPGP_02058 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
JGNPNPGP_02059 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JGNPNPGP_02060 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JGNPNPGP_02061 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JGNPNPGP_02062 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JGNPNPGP_02063 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JGNPNPGP_02064 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
JGNPNPGP_02065 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JGNPNPGP_02066 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JGNPNPGP_02067 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JGNPNPGP_02068 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JGNPNPGP_02069 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JGNPNPGP_02070 3.2e-95 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JGNPNPGP_02071 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JGNPNPGP_02072 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JGNPNPGP_02073 2.9e-24 rpmD J Ribosomal protein L30
JGNPNPGP_02074 8.9e-64 rplO J Binds to the 23S rRNA
JGNPNPGP_02075 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
JGNPNPGP_02076 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
JGNPNPGP_02077 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JGNPNPGP_02078 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
JGNPNPGP_02079 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JGNPNPGP_02080 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JGNPNPGP_02081 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JGNPNPGP_02082 1.1e-62 rplQ J Ribosomal protein L17
JGNPNPGP_02083 8e-146 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JGNPNPGP_02084 4.3e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JGNPNPGP_02085 7.5e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JGNPNPGP_02086 6.5e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
JGNPNPGP_02087 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JGNPNPGP_02088 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
JGNPNPGP_02089 9.4e-141 IQ reductase
JGNPNPGP_02090 1e-113 acmC 3.2.1.96 NU mannosyl-glycoprotein
JGNPNPGP_02091 4.6e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
JGNPNPGP_02092 2.7e-213 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
JGNPNPGP_02093 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
JGNPNPGP_02094 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JGNPNPGP_02095 6.2e-202 camS S sex pheromone
JGNPNPGP_02096 4.5e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JGNPNPGP_02097 4.1e-278 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
JGNPNPGP_02098 4.1e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JGNPNPGP_02099 3e-187 yegS 2.7.1.107 G Lipid kinase
JGNPNPGP_02100 2e-12
JGNPNPGP_02101 3e-34 doc S Fic/DOC family
JGNPNPGP_02102 1.7e-262 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)