ORF_ID e_value Gene_name EC_number CAZy COGs Description
LEMALOII_00001 1.3e-235 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LEMALOII_00002 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LEMALOII_00003 2.4e-33 yaaA S S4 domain
LEMALOII_00004 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LEMALOII_00005 1.8e-37 yaaB S Domain of unknown function (DUF370)
LEMALOII_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LEMALOII_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LEMALOII_00008 3.4e-39 S COG NOG14552 non supervised orthologous group
LEMALOII_00011 2.7e-182 yaaC S YaaC-like Protein
LEMALOII_00012 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
LEMALOII_00013 5.2e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
LEMALOII_00014 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LEMALOII_00015 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LEMALOII_00016 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LEMALOII_00017 1.3e-09
LEMALOII_00018 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
LEMALOII_00019 3.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
LEMALOII_00020 5.6e-215 yaaH M Glycoside Hydrolase Family
LEMALOII_00021 2.4e-98 yaaI Q COG1335 Amidases related to nicotinamidase
LEMALOII_00022 1e-84 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LEMALOII_00023 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LEMALOII_00024 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LEMALOII_00025 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LEMALOII_00026 7.9e-32 yaaL S Protein of unknown function (DUF2508)
LEMALOII_00027 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
LEMALOII_00028 3.4e-39 S COG NOG14552 non supervised orthologous group
LEMALOII_00031 3.4e-31 csfB S Inhibitor of sigma-G Gin
LEMALOII_00032 4.7e-103 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
LEMALOII_00033 4.5e-203 yaaN P Belongs to the TelA family
LEMALOII_00034 1.1e-275 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
LEMALOII_00035 3.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LEMALOII_00036 2.2e-54 yaaQ S protein conserved in bacteria
LEMALOII_00037 1.5e-71 yaaR S protein conserved in bacteria
LEMALOII_00038 2.2e-182 holB 2.7.7.7 L DNA polymerase III
LEMALOII_00039 2.1e-146 yaaT S stage 0 sporulation protein
LEMALOII_00040 4.8e-31 yabA L Involved in initiation control of chromosome replication
LEMALOII_00041 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
LEMALOII_00042 1.5e-49 yazA L endonuclease containing a URI domain
LEMALOII_00043 4.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LEMALOII_00044 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
LEMALOII_00045 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LEMALOII_00046 1.8e-144 tatD L hydrolase, TatD
LEMALOII_00047 4.3e-194 rpfB GH23 T protein conserved in bacteria
LEMALOII_00048 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LEMALOII_00049 2.4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LEMALOII_00050 3.3e-137 yabG S peptidase
LEMALOII_00051 7.8e-39 veg S protein conserved in bacteria
LEMALOII_00052 8.3e-27 sspF S DNA topological change
LEMALOII_00053 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LEMALOII_00054 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
LEMALOII_00055 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
LEMALOII_00056 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
LEMALOII_00057 6.6e-230 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LEMALOII_00058 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LEMALOII_00059 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LEMALOII_00060 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LEMALOII_00061 2.4e-39 yabK S Peptide ABC transporter permease
LEMALOII_00062 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LEMALOII_00063 1.5e-92 spoVT K stage V sporulation protein
LEMALOII_00064 2.4e-287 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LEMALOII_00065 2.7e-245 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
LEMALOII_00066 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
LEMALOII_00067 1.5e-49 yabP S Sporulation protein YabP
LEMALOII_00068 3.9e-108 yabQ S spore cortex biosynthesis protein
LEMALOII_00069 1.1e-44 divIC D Septum formation initiator
LEMALOII_00070 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
LEMALOII_00073 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
LEMALOII_00074 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
LEMALOII_00075 6.7e-187 KLT serine threonine protein kinase
LEMALOII_00076 3.5e-274 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LEMALOII_00077 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
LEMALOII_00078 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LEMALOII_00079 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LEMALOII_00080 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LEMALOII_00081 3.1e-153 yacD 5.2.1.8 O peptidyl-prolyl isomerase
LEMALOII_00082 8.9e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
LEMALOII_00083 4.7e-271 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LEMALOII_00084 1.5e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
LEMALOII_00085 1.6e-168 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
LEMALOII_00086 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LEMALOII_00087 8.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LEMALOII_00088 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LEMALOII_00089 4.1e-30 yazB K transcriptional
LEMALOII_00090 3.7e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LEMALOII_00091 1.3e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
LEMALOII_00092 3.4e-39 S COG NOG14552 non supervised orthologous group
LEMALOII_00097 2e-08
LEMALOII_00102 3.4e-39 S COG NOG14552 non supervised orthologous group
LEMALOII_00103 2.9e-76 ctsR K Belongs to the CtsR family
LEMALOII_00104 4.7e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
LEMALOII_00105 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
LEMALOII_00106 0.0 clpC O Belongs to the ClpA ClpB family
LEMALOII_00107 9.6e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LEMALOII_00108 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LEMALOII_00109 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
LEMALOII_00110 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
LEMALOII_00111 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
LEMALOII_00112 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LEMALOII_00113 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
LEMALOII_00114 4.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
LEMALOII_00115 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LEMALOII_00116 1.2e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LEMALOII_00117 1.2e-88 yacP S RNA-binding protein containing a PIN domain
LEMALOII_00118 4.4e-115 sigH K Belongs to the sigma-70 factor family
LEMALOII_00119 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LEMALOII_00120 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
LEMALOII_00121 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LEMALOII_00122 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LEMALOII_00123 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LEMALOII_00124 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LEMALOII_00125 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
LEMALOII_00126 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEMALOII_00127 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEMALOII_00128 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
LEMALOII_00129 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LEMALOII_00130 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LEMALOII_00131 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LEMALOII_00132 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LEMALOII_00133 9.1e-186 ybaC 3.4.11.5 S Alpha/beta hydrolase family
LEMALOII_00134 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
LEMALOII_00135 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LEMALOII_00136 3e-105 rplD J Forms part of the polypeptide exit tunnel
LEMALOII_00137 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LEMALOII_00138 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LEMALOII_00139 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LEMALOII_00140 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LEMALOII_00141 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LEMALOII_00142 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LEMALOII_00143 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
LEMALOII_00144 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LEMALOII_00145 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LEMALOII_00146 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LEMALOII_00147 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LEMALOII_00148 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LEMALOII_00149 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LEMALOII_00150 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LEMALOII_00151 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LEMALOII_00152 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LEMALOII_00153 1.9e-23 rpmD J Ribosomal protein L30
LEMALOII_00154 1.8e-72 rplO J binds to the 23S rRNA
LEMALOII_00155 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LEMALOII_00156 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LEMALOII_00157 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
LEMALOII_00158 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LEMALOII_00159 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
LEMALOII_00160 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LEMALOII_00161 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LEMALOII_00162 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEMALOII_00163 3.6e-58 rplQ J Ribosomal protein L17
LEMALOII_00164 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LEMALOII_00165 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LEMALOII_00166 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LEMALOII_00167 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LEMALOII_00168 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LEMALOII_00169 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
LEMALOII_00170 8.2e-145 ybaJ Q Methyltransferase domain
LEMALOII_00171 9.7e-66 ybaK S Protein of unknown function (DUF2521)
LEMALOII_00172 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LEMALOII_00173 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
LEMALOII_00174 1.2e-84 gerD
LEMALOII_00175 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
LEMALOII_00176 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
LEMALOII_00177 3.4e-39 S COG NOG14552 non supervised orthologous group
LEMALOII_00180 2e-08
LEMALOII_00184 3.4e-39 S COG NOG14552 non supervised orthologous group
LEMALOII_00185 3.4e-39 S COG NOG14552 non supervised orthologous group
LEMALOII_00186 4.6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
LEMALOII_00188 1.2e-161 ybaS 1.1.1.58 S Na -dependent transporter
LEMALOII_00189 2.2e-142 ybbA S Putative esterase
LEMALOII_00190 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEMALOII_00191 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEMALOII_00192 7.2e-167 feuA P Iron-uptake system-binding protein
LEMALOII_00193 5.4e-308 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
LEMALOII_00194 4.4e-241 ybbC 3.2.1.52 S protein conserved in bacteria
LEMALOII_00195 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
LEMALOII_00196 4e-256 yfeW 3.4.16.4 V Belongs to the UPF0214 family
LEMALOII_00197 9.8e-234 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LEMALOII_00198 1.1e-150 ybbH K transcriptional
LEMALOII_00199 2.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LEMALOII_00200 6.4e-87 ybbJ J acetyltransferase
LEMALOII_00201 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
LEMALOII_00207 8.5e-99 sigW K Belongs to the sigma-70 factor family. ECF subfamily
LEMALOII_00208 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
LEMALOII_00209 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LEMALOII_00210 3e-225 ybbR S protein conserved in bacteria
LEMALOII_00211 9.3e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LEMALOII_00212 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LEMALOII_00213 2.1e-176 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LEMALOII_00214 1.4e-121 adaA 3.2.2.21 K Transcriptional regulator
LEMALOII_00215 5.1e-101 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LEMALOII_00216 1.5e-278 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
LEMALOII_00217 0.0 ybcC S Belongs to the UPF0753 family
LEMALOII_00218 3.7e-96 can 4.2.1.1 P carbonic anhydrase
LEMALOII_00219 3.9e-47
LEMALOII_00220 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
LEMALOII_00221 5.1e-50 ybzH K Helix-turn-helix domain
LEMALOII_00222 2e-203 ybcL EGP Major facilitator Superfamily
LEMALOII_00224 9.1e-239 J 4Fe-4S single cluster domain
LEMALOII_00225 1.6e-277 V CAAX protease self-immunity
LEMALOII_00226 1.9e-135 skfE V ABC transporter
LEMALOII_00227 4e-248 skfF S ABC transporter
LEMALOII_00228 7.8e-91 C HEAT repeats
LEMALOII_00229 9.6e-79 txn CO Thioredoxin-like
LEMALOII_00230 6.2e-182 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LEMALOII_00231 1.5e-123 T Transcriptional regulatory protein, C terminal
LEMALOII_00232 1.8e-173 T His Kinase A (phospho-acceptor) domain
LEMALOII_00234 1.6e-140 KLT Protein tyrosine kinase
LEMALOII_00235 4.8e-154 ybdN
LEMALOII_00236 1.5e-217 ybdO S Domain of unknown function (DUF4885)
LEMALOII_00237 2.4e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
LEMALOII_00238 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
LEMALOII_00239 4.9e-30 ybxH S Family of unknown function (DUF5370)
LEMALOII_00240 2.1e-151 ybxI 3.5.2.6 V beta-lactamase
LEMALOII_00241 1.4e-247 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
LEMALOII_00242 4.9e-41 ybyB
LEMALOII_00243 2.3e-290 ybeC E amino acid
LEMALOII_00244 5.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LEMALOII_00245 7.3e-258 glpT G -transporter
LEMALOII_00246 2.9e-35 S Protein of unknown function (DUF2651)
LEMALOII_00247 1.6e-171 ybfA 3.4.15.5 K FR47-like protein
LEMALOII_00248 2.2e-224 ybfB G COG0477 Permeases of the major facilitator superfamily
LEMALOII_00250 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
LEMALOII_00251 8.8e-162 ybfH EG EamA-like transporter family
LEMALOII_00252 2.3e-145 msmR K AraC-like ligand binding domain
LEMALOII_00253 1.9e-214 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LEMALOII_00254 6.9e-178 mpr 3.4.21.19 M Belongs to the peptidase S1B family
LEMALOII_00256 2.5e-169 S Alpha/beta hydrolase family
LEMALOII_00257 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LEMALOII_00258 2.7e-85 ybfM S SNARE associated Golgi protein
LEMALOII_00259 5.6e-149 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
LEMALOII_00260 3.2e-46 ybfN
LEMALOII_00261 4.3e-258 S Erythromycin esterase
LEMALOII_00262 6.7e-167 ybfP K Transcriptional regulator
LEMALOII_00263 3.9e-192 yceA S Belongs to the UPF0176 family
LEMALOII_00264 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LEMALOII_00265 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LEMALOII_00266 2.1e-137 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LEMALOII_00267 4.9e-128 K UTRA
LEMALOII_00269 5.4e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
LEMALOII_00270 6.7e-262 mmuP E amino acid
LEMALOII_00271 9.3e-183 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
LEMALOII_00272 2.3e-257 agcS E Sodium alanine symporter
LEMALOII_00273 1.5e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
LEMALOII_00274 1.5e-229 phoQ 2.7.13.3 T Histidine kinase
LEMALOII_00275 9e-170 glnL T Regulator
LEMALOII_00276 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
LEMALOII_00277 3.7e-274 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LEMALOII_00278 1.2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
LEMALOII_00279 2.2e-270 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
LEMALOII_00280 1.5e-124 ycbG K FCD
LEMALOII_00281 3.7e-298 garD 4.2.1.42, 4.2.1.7 G Altronate
LEMALOII_00282 1.8e-178 ycbJ S Macrolide 2'-phosphotransferase
LEMALOII_00283 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
LEMALOII_00284 7.3e-172 eamA1 EG spore germination
LEMALOII_00285 1.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEMALOII_00286 2.4e-170 T PhoQ Sensor
LEMALOII_00287 4.8e-168 ycbN V ABC transporter, ATP-binding protein
LEMALOII_00288 2.1e-115 S ABC-2 family transporter protein
LEMALOII_00289 8.2e-53 ycbP S Protein of unknown function (DUF2512)
LEMALOII_00290 1.3e-78 sleB 3.5.1.28 M Cell wall
LEMALOII_00291 6.6e-136 ycbR T vWA found in TerF C terminus
LEMALOII_00292 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
LEMALOII_00293 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
LEMALOII_00294 1.2e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LEMALOII_00295 1.4e-121 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LEMALOII_00296 6.2e-210 ycbU E Selenocysteine lyase
LEMALOII_00297 5.8e-229 lmrB EGP the major facilitator superfamily
LEMALOII_00298 4.8e-102 yxaF K Transcriptional regulator
LEMALOII_00299 2.2e-202 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
LEMALOII_00300 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
LEMALOII_00301 2e-59 S RDD family
LEMALOII_00302 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
LEMALOII_00303 2e-161 2.7.13.3 T GHKL domain
LEMALOII_00304 1.2e-126 lytR_2 T LytTr DNA-binding domain
LEMALOII_00305 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
LEMALOII_00306 4.5e-203 natB CP ABC-2 family transporter protein
LEMALOII_00307 1.6e-174 yccK C Aldo keto reductase
LEMALOII_00308 6.6e-177 ycdA S Domain of unknown function (DUF5105)
LEMALOII_00309 5.9e-282 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
LEMALOII_00310 6.7e-268 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
LEMALOII_00311 1.7e-95 cwlK M D-alanyl-D-alanine carboxypeptidase
LEMALOII_00312 5.5e-174 S response regulator aspartate phosphatase
LEMALOII_00313 1.6e-140 IQ Enoyl-(Acyl carrier protein) reductase
LEMALOII_00314 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
LEMALOII_00315 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
LEMALOII_00316 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
LEMALOII_00317 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
LEMALOII_00318 5.4e-189 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LEMALOII_00319 3.9e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
LEMALOII_00320 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
LEMALOII_00321 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
LEMALOII_00322 6.3e-137 terC P Protein of unknown function (DUF475)
LEMALOII_00323 0.0 yceG S Putative component of 'biosynthetic module'
LEMALOII_00324 2e-192 yceH P Belongs to the TelA family
LEMALOII_00325 1e-218 naiP P Uncharacterised MFS-type transporter YbfB
LEMALOII_00326 1.9e-209 yceJ EGP Uncharacterised MFS-type transporter YbfB
LEMALOII_00327 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
LEMALOII_00328 5.1e-229 proV 3.6.3.32 E glycine betaine
LEMALOII_00329 1.3e-127 opuAB P glycine betaine
LEMALOII_00330 5.3e-164 opuAC E glycine betaine
LEMALOII_00331 1.2e-219 amhX S amidohydrolase
LEMALOII_00332 8.7e-257 ycgA S Membrane
LEMALOII_00333 1.1e-98 ycgB
LEMALOII_00334 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
LEMALOII_00335 3.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
LEMALOII_00336 6.5e-293 lctP C L-lactate permease
LEMALOII_00337 6.2e-269 mdr EGP Major facilitator Superfamily
LEMALOII_00338 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
LEMALOII_00339 6.8e-113 ycgF E Lysine exporter protein LysE YggA
LEMALOII_00340 1.2e-151 yqcI S YqcI/YcgG family
LEMALOII_00341 5.6e-250 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
LEMALOII_00342 2.4e-112 ycgI S Domain of unknown function (DUF1989)
LEMALOII_00343 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LEMALOII_00344 2.5e-109 tmrB S AAA domain
LEMALOII_00345 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LEMALOII_00346 3.6e-145 yafE Q ubiE/COQ5 methyltransferase family
LEMALOII_00347 2.2e-179 oxyR3 K LysR substrate binding domain
LEMALOII_00348 2.9e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
LEMALOII_00349 2.9e-145 ycgL S Predicted nucleotidyltransferase
LEMALOII_00350 5.1e-170 ycgM E Proline dehydrogenase
LEMALOII_00351 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
LEMALOII_00352 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LEMALOII_00353 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
LEMALOII_00354 2.6e-147 ycgQ S membrane
LEMALOII_00355 1.2e-139 ycgR S permeases
LEMALOII_00356 5.7e-163 I alpha/beta hydrolase fold
LEMALOII_00357 1.3e-193 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
LEMALOII_00358 9.3e-283 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
LEMALOII_00359 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
LEMALOII_00360 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LEMALOII_00361 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LEMALOII_00362 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
LEMALOII_00363 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
LEMALOII_00364 1.4e-172 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
LEMALOII_00365 5.5e-109 yciB M ErfK YbiS YcfS YnhG
LEMALOII_00366 1.4e-228 yciC S GTPases (G3E family)
LEMALOII_00367 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
LEMALOII_00368 1.1e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
LEMALOII_00371 3.3e-77 yckC S membrane
LEMALOII_00372 3.5e-52 yckD S Protein of unknown function (DUF2680)
LEMALOII_00373 1.2e-298 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LEMALOII_00374 3.4e-70 nin S Competence protein J (ComJ)
LEMALOII_00375 3.2e-72 nucA M Deoxyribonuclease NucA/NucB
LEMALOII_00376 3e-187 tlpC 2.7.13.3 NT chemotaxis protein
LEMALOII_00377 4.6e-97 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
LEMALOII_00378 3.3e-107 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
LEMALOII_00379 1.3e-63 hxlR K transcriptional
LEMALOII_00380 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEMALOII_00381 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEMALOII_00382 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
LEMALOII_00383 5.7e-140 srfAD Q thioesterase
LEMALOII_00384 4.2e-228 EGP Major Facilitator Superfamily
LEMALOII_00385 4.9e-91 S YcxB-like protein
LEMALOII_00386 7.4e-164 ycxC EG EamA-like transporter family
LEMALOII_00387 4.4e-255 ycxD K GntR family transcriptional regulator
LEMALOII_00388 5.5e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
LEMALOII_00389 4.4e-115 yczE S membrane
LEMALOII_00390 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
LEMALOII_00391 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
LEMALOII_00392 1.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
LEMALOII_00393 4.9e-162 bsdA K LysR substrate binding domain
LEMALOII_00394 2e-109 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
LEMALOII_00395 1.8e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
LEMALOII_00396 4e-39 bsdD 4.1.1.61 S response to toxic substance
LEMALOII_00397 1.1e-83 yclD
LEMALOII_00398 6.2e-162 yclE 3.4.11.5 S Alpha beta hydrolase
LEMALOII_00399 1.5e-267 dtpT E amino acid peptide transporter
LEMALOII_00400 2.9e-310 yclG M Pectate lyase superfamily protein
LEMALOII_00402 6.8e-282 gerKA EG Spore germination protein
LEMALOII_00403 1.3e-232 gerKC S spore germination
LEMALOII_00404 9.9e-200 gerKB F Spore germination protein
LEMALOII_00405 3.9e-122 yclH P ABC transporter
LEMALOII_00406 1.7e-204 yclI V ABC transporter (permease) YclI
LEMALOII_00407 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEMALOII_00408 1.8e-262 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
LEMALOII_00409 5.2e-71 S aspartate phosphatase
LEMALOII_00412 7.5e-242 lysC 2.7.2.4 E Belongs to the aspartokinase family
LEMALOII_00413 1.6e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEMALOII_00414 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEMALOII_00415 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
LEMALOII_00416 5.5e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
LEMALOII_00417 1.4e-251 ycnB EGP Major facilitator Superfamily
LEMALOII_00418 6.5e-154 ycnC K Transcriptional regulator
LEMALOII_00419 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
LEMALOII_00420 1.6e-45 ycnE S Monooxygenase
LEMALOII_00421 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
LEMALOII_00422 1.3e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LEMALOII_00423 4.4e-247 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LEMALOII_00424 3.4e-266 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LEMALOII_00425 6.1e-149 glcU U Glucose uptake
LEMALOII_00426 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEMALOII_00427 1.3e-100 ycnI S protein conserved in bacteria
LEMALOII_00428 1.4e-308 ycnJ P protein, homolog of Cu resistance protein CopC
LEMALOII_00429 1.7e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
LEMALOII_00430 7.3e-56
LEMALOII_00431 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
LEMALOII_00432 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
LEMALOII_00433 7.3e-211 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
LEMALOII_00434 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
LEMALOII_00435 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
LEMALOII_00436 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
LEMALOII_00437 5e-113 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
LEMALOII_00438 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
LEMALOII_00440 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
LEMALOII_00441 1.2e-140 ycsF S Belongs to the UPF0271 (lamB) family
LEMALOII_00442 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
LEMALOII_00443 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
LEMALOII_00444 1.9e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
LEMALOII_00445 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
LEMALOII_00446 1.2e-132 kipR K Transcriptional regulator
LEMALOII_00447 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
LEMALOII_00449 1.4e-49 yczJ S biosynthesis
LEMALOII_00450 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
LEMALOII_00451 2.8e-176 ydhF S Oxidoreductase
LEMALOII_00452 0.0 mtlR K transcriptional regulator, MtlR
LEMALOII_00453 1.4e-294 ydaB IQ acyl-CoA ligase
LEMALOII_00454 1.1e-99 ydaC Q Methyltransferase domain
LEMALOII_00455 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEMALOII_00456 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
LEMALOII_00457 5e-104 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LEMALOII_00458 6.8e-77 ydaG 1.4.3.5 S general stress protein
LEMALOII_00459 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
LEMALOII_00460 5.1e-47 ydzA EGP Major facilitator Superfamily
LEMALOII_00461 2.5e-74 lrpC K Transcriptional regulator
LEMALOII_00462 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LEMALOII_00463 1.9e-208 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
LEMALOII_00464 2e-152 ydaK T Diguanylate cyclase, GGDEF domain
LEMALOII_00465 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
LEMALOII_00466 4.5e-233 ydaM M Glycosyl transferase family group 2
LEMALOII_00467 0.0 ydaN S Bacterial cellulose synthase subunit
LEMALOII_00468 0.0 ydaO E amino acid
LEMALOII_00469 4.6e-79 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
LEMALOII_00470 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
LEMALOII_00471 9.4e-40
LEMALOII_00472 1e-224 mntH P H( )-stimulated, divalent metal cation uptake system
LEMALOII_00474 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
LEMALOII_00475 3.8e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
LEMALOII_00477 8.9e-59 ydbB G Cupin domain
LEMALOII_00478 2.8e-63 ydbC S Domain of unknown function (DUF4937
LEMALOII_00479 3.2e-155 ydbD P Catalase
LEMALOII_00480 2.7e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
LEMALOII_00481 2.5e-297 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
LEMALOII_00482 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
LEMALOII_00483 6.3e-227 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LEMALOII_00484 4.4e-181 ydbI S AI-2E family transporter
LEMALOII_00485 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
LEMALOII_00486 5.5e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LEMALOII_00487 2.7e-52 ydbL
LEMALOII_00488 3e-220 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
LEMALOII_00489 1.1e-18 S Fur-regulated basic protein B
LEMALOII_00490 2.2e-07 S Fur-regulated basic protein A
LEMALOII_00491 1.9e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LEMALOII_00492 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
LEMALOII_00493 4.6e-202 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
LEMALOII_00494 1.9e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LEMALOII_00495 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LEMALOII_00496 2.1e-82 ydbS S Bacterial PH domain
LEMALOII_00497 2.2e-263 ydbT S Membrane
LEMALOII_00498 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
LEMALOII_00499 2.5e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LEMALOII_00500 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
LEMALOII_00501 2.3e-223 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LEMALOII_00502 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
LEMALOII_00503 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
LEMALOII_00504 1.3e-143 rsbR T Positive regulator of sigma-B
LEMALOII_00505 5.2e-57 rsbS T antagonist
LEMALOII_00506 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
LEMALOII_00507 7.1e-189 rsbU 3.1.3.3 KT phosphatase
LEMALOII_00508 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
LEMALOII_00509 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
LEMALOII_00510 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEMALOII_00511 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
LEMALOII_00515 1.5e-82 ydcG S EVE domain
LEMALOII_00516 1.6e-76 ydcH K helix_turn_helix multiple antibiotic resistance protein
LEMALOII_00517 0.0 yhgF K COG2183 Transcriptional accessory protein
LEMALOII_00518 1.6e-84 ydcK S Belongs to the SprT family
LEMALOII_00526 2.7e-188 luxA C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LEMALOII_00527 2.4e-71 lrpA K transcriptional
LEMALOII_00528 3.9e-78 lrpB K transcriptional
LEMALOII_00529 9.6e-100 yddQ 3.5.1.19 Q Isochorismatase family
LEMALOII_00530 1.5e-143 yddR S Zn-dependent hydrolases of the beta-lactamase fold
LEMALOII_00531 5e-227 ydeG EGP Major facilitator Superfamily
LEMALOII_00536 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
LEMALOII_00537 8.7e-30 cspL K Cold shock
LEMALOII_00538 6.1e-79 carD K Transcription factor
LEMALOII_00539 4.6e-35 ydzE EG spore germination
LEMALOII_00540 1.1e-166 rhaS5 K AraC-like ligand binding domain
LEMALOII_00541 2.3e-173 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LEMALOII_00542 2.5e-166 ydeE K AraC family transcriptional regulator
LEMALOII_00543 2.2e-265 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LEMALOII_00544 3.4e-220 ydeG EGP Major facilitator superfamily
LEMALOII_00545 2.9e-47 ydeH
LEMALOII_00546 8.9e-107 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
LEMALOII_00547 4e-116
LEMALOII_00548 1.8e-153 ydeK EG -transporter
LEMALOII_00549 1.5e-274 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LEMALOII_00550 4.2e-74 maoC I N-terminal half of MaoC dehydratase
LEMALOII_00551 8.6e-107 ydeN S Serine hydrolase
LEMALOII_00552 1.1e-58 K HxlR-like helix-turn-helix
LEMALOII_00553 1.9e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
LEMALOII_00554 4.8e-69 ydeP K Transcriptional regulator
LEMALOII_00555 1.6e-108 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
LEMALOII_00556 1.2e-195 ydeR EGP Major facilitator Superfamily
LEMALOII_00557 8.4e-105 ydeS K Transcriptional regulator
LEMALOII_00558 1.3e-57 arsR K transcriptional
LEMALOII_00559 5.2e-232 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LEMALOII_00560 7.2e-149 ydfB J GNAT acetyltransferase
LEMALOII_00561 1e-162 ydfC EG EamA-like transporter family
LEMALOII_00562 1.9e-275 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LEMALOII_00563 5.9e-117 ydfE S Flavin reductase like domain
LEMALOII_00564 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
LEMALOII_00565 1.5e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LEMALOII_00567 5.3e-180 ydfH 2.7.13.3 T Histidine kinase
LEMALOII_00568 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LEMALOII_00569 0.0 ydfJ S drug exporters of the RND superfamily
LEMALOII_00570 1.9e-177 S Alpha/beta hydrolase family
LEMALOII_00571 5.9e-118 S Protein of unknown function (DUF554)
LEMALOII_00572 3.2e-147 K Bacterial transcription activator, effector binding domain
LEMALOII_00573 1.6e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LEMALOII_00574 9.6e-112 ydfN C nitroreductase
LEMALOII_00575 3.6e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
LEMALOII_00576 8.8e-63 mhqP S DoxX
LEMALOII_00577 1.3e-57 traF CO Thioredoxin
LEMALOII_00578 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
LEMALOII_00579 6.3e-29
LEMALOII_00581 4.4e-118 ydfR S Protein of unknown function (DUF421)
LEMALOII_00582 5.2e-122 ydfS S Protein of unknown function (DUF421)
LEMALOII_00583 1.7e-75 cotP O Belongs to the small heat shock protein (HSP20) family
LEMALOII_00584 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
LEMALOII_00585 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
LEMALOII_00586 1.5e-101 K Bacterial regulatory proteins, tetR family
LEMALOII_00587 7.3e-53 S DoxX-like family
LEMALOII_00588 2.4e-86 yycN 2.3.1.128 K Acetyltransferase
LEMALOII_00589 4.2e-308 expZ S ABC transporter
LEMALOII_00590 4e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
LEMALOII_00591 4.6e-91 dinB S DinB family
LEMALOII_00592 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
LEMALOII_00593 0.0 ydgH S drug exporters of the RND superfamily
LEMALOII_00594 1e-113 drgA C nitroreductase
LEMALOII_00595 1.1e-69 ydgJ K Winged helix DNA-binding domain
LEMALOII_00596 2.5e-209 tcaB EGP Major facilitator Superfamily
LEMALOII_00597 1.2e-121 ydhB S membrane transporter protein
LEMALOII_00598 6.5e-122 ydhC K FCD
LEMALOII_00599 3.3e-244 ydhD M Glycosyl hydrolase
LEMALOII_00600 7e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
LEMALOII_00601 1.9e-127
LEMALOII_00602 1.4e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
LEMALOII_00603 4.6e-69 frataxin S Domain of unknown function (DU1801)
LEMALOII_00605 4.1e-86 K Acetyltransferase (GNAT) domain
LEMALOII_00606 1.8e-184 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
LEMALOII_00607 1.7e-99 ydhK M Protein of unknown function (DUF1541)
LEMALOII_00608 4.6e-200 pbuE EGP Major facilitator Superfamily
LEMALOII_00609 1.1e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
LEMALOII_00610 3.5e-52 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
LEMALOII_00611 2e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEMALOII_00612 2.4e-288 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LEMALOII_00613 3.9e-133 ydhQ K UTRA
LEMALOII_00614 9.2e-172 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
LEMALOII_00615 4.2e-191 manA 5.3.1.8 G mannose-6-phosphate isomerase
LEMALOII_00616 7.3e-216 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
LEMALOII_00617 8.7e-78 ydhU P Catalase
LEMALOII_00618 1.1e-16 ydhU P Manganese containing catalase
LEMALOII_00621 3.4e-39 S COG NOG14552 non supervised orthologous group
LEMALOII_00622 7.8e-08
LEMALOII_00624 4.6e-185 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LEMALOII_00625 9.1e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
LEMALOII_00626 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
LEMALOII_00627 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
LEMALOII_00628 3.6e-188 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LEMALOII_00629 0.0 ydiF S ABC transporter
LEMALOII_00630 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
LEMALOII_00631 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LEMALOII_00632 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
LEMALOII_00633 8.4e-126 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LEMALOII_00634 2.9e-27 ydiK S Domain of unknown function (DUF4305)
LEMALOII_00635 7.9e-129 ydiL S CAAX protease self-immunity
LEMALOII_00636 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LEMALOII_00637 1.2e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LEMALOII_00639 6.4e-66 KL Phage plasmid primase P4 family
LEMALOII_00640 1.1e-250 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
LEMALOII_00641 6e-232 ydiP 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
LEMALOII_00643 1.2e-199 V AAA domain (dynein-related subfamily)
LEMALOII_00644 4.9e-257 J LlaJI restriction endonuclease
LEMALOII_00645 1.1e-08 ydjC S Abhydrolase domain containing 18
LEMALOII_00646 0.0 K NB-ARC domain
LEMALOII_00647 3.8e-201 gutB 1.1.1.14 E Dehydrogenase
LEMALOII_00648 7.1e-256 gutA G MFS/sugar transport protein
LEMALOII_00649 1.5e-175 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
LEMALOII_00650 5.1e-114 pspA KT Phage shock protein A
LEMALOII_00651 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LEMALOII_00652 1.6e-137 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
LEMALOII_00653 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
LEMALOII_00654 4.7e-196 S Ion transport 2 domain protein
LEMALOII_00655 2.7e-258 iolT EGP Major facilitator Superfamily
LEMALOII_00656 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
LEMALOII_00657 4.5e-64 ydjM M Lytic transglycolase
LEMALOII_00658 4.4e-157 ydjN U Involved in the tonB-independent uptake of proteins
LEMALOII_00660 1.4e-34 ydjO S Cold-inducible protein YdjO
LEMALOII_00661 9.5e-160 ydjP I Alpha/beta hydrolase family
LEMALOII_00662 2.4e-181 yeaA S Protein of unknown function (DUF4003)
LEMALOII_00663 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
LEMALOII_00664 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
LEMALOII_00665 7.6e-155 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LEMALOII_00666 1.6e-177 yeaC S COG0714 MoxR-like ATPases
LEMALOII_00667 9.5e-225 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
LEMALOII_00668 0.0 yebA E COG1305 Transglutaminase-like enzymes
LEMALOII_00669 3.7e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
LEMALOII_00670 6e-212 pbuG S permease
LEMALOII_00671 1.1e-118 yebC M Membrane
LEMALOII_00673 4e-93 yebE S UPF0316 protein
LEMALOII_00674 8e-28 yebG S NETI protein
LEMALOII_00675 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LEMALOII_00676 7e-217 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LEMALOII_00677 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LEMALOII_00678 1.2e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
LEMALOII_00679 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LEMALOII_00680 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LEMALOII_00681 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LEMALOII_00682 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LEMALOII_00683 7.6e-178 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
LEMALOII_00684 1.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LEMALOII_00685 1.2e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
LEMALOII_00686 1.7e-235 purD 6.3.4.13 F Belongs to the GARS family
LEMALOII_00687 3.5e-73 K helix_turn_helix ASNC type
LEMALOII_00688 2.3e-232 yjeH E Amino acid permease
LEMALOII_00689 2.7e-27 S Protein of unknown function (DUF2892)
LEMALOII_00690 0.0 yerA 3.5.4.2 F adenine deaminase
LEMALOII_00691 3e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
LEMALOII_00692 4.8e-51 yerC S protein conserved in bacteria
LEMALOII_00693 3.2e-305 yerD 1.4.7.1 E Belongs to the glutamate synthase family
LEMALOII_00695 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
LEMALOII_00696 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
LEMALOII_00697 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LEMALOII_00698 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
LEMALOII_00699 1.1e-197 yerI S homoserine kinase type II (protein kinase fold)
LEMALOII_00700 1.6e-123 sapB S MgtC SapB transporter
LEMALOII_00701 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LEMALOII_00702 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LEMALOII_00703 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LEMALOII_00704 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LEMALOII_00705 4e-156 yerO K Transcriptional regulator
LEMALOII_00706 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LEMALOII_00707 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LEMALOII_00708 1.2e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LEMALOII_00709 3.2e-98 L Recombinase
LEMALOII_00710 3.2e-53 L Resolvase, N terminal domain
LEMALOII_00711 0.0 yeeA V Type II restriction enzyme, methylase subunits
LEMALOII_00712 0.0 yeeB L DEAD-like helicases superfamily
LEMALOII_00713 1.2e-211 pstS P T5orf172
LEMALOII_00715 6.2e-31 S Colicin immunity protein / pyocin immunity protein
LEMALOII_00716 5.5e-83 S Protein of unknown function, DUF600
LEMALOII_00717 0.0 L nucleic acid phosphodiester bond hydrolysis
LEMALOII_00718 1.8e-192 3.4.24.40 CO amine dehydrogenase activity
LEMALOII_00719 5.5e-214 S Tetratricopeptide repeat
LEMALOII_00721 9.4e-127 yeeN K transcriptional regulatory protein
LEMALOII_00723 1.2e-103 dhaR3 K Transcriptional regulator
LEMALOII_00724 9.7e-82 yesE S SnoaL-like domain
LEMALOII_00725 2.2e-159 yesF GM NAD(P)H-binding
LEMALOII_00726 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
LEMALOII_00727 1.5e-45 cotJB S CotJB protein
LEMALOII_00728 5.2e-104 cotJC P Spore Coat
LEMALOII_00729 4.2e-103 yesJ K Acetyltransferase (GNAT) family
LEMALOII_00731 4.4e-104 yesL S Protein of unknown function, DUF624
LEMALOII_00732 0.0 yesM 2.7.13.3 T Histidine kinase
LEMALOII_00733 2.9e-204 yesN K helix_turn_helix, arabinose operon control protein
LEMALOII_00734 5e-248 yesO G Bacterial extracellular solute-binding protein
LEMALOII_00735 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
LEMALOII_00736 1.3e-165 yesQ P Binding-protein-dependent transport system inner membrane component
LEMALOII_00737 1.6e-199 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
LEMALOII_00738 0.0 yesS K Transcriptional regulator
LEMALOII_00739 3.8e-133 E GDSL-like Lipase/Acylhydrolase
LEMALOII_00740 8.9e-132 yesU S Domain of unknown function (DUF1961)
LEMALOII_00741 1e-113 yesV S Protein of unknown function, DUF624
LEMALOII_00742 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
LEMALOII_00743 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
LEMALOII_00744 3e-124 yesY E GDSL-like Lipase/Acylhydrolase
LEMALOII_00745 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
LEMALOII_00746 0.0 yetA
LEMALOII_00747 9.6e-291 lplA G Bacterial extracellular solute-binding protein
LEMALOII_00748 1.3e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
LEMALOII_00749 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
LEMALOII_00750 3.3e-258 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
LEMALOII_00751 6.1e-123 yetF S membrane
LEMALOII_00752 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
LEMALOII_00753 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEMALOII_00754 2.2e-34
LEMALOII_00755 2.2e-89 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LEMALOII_00756 4.4e-43 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LEMALOII_00757 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
LEMALOII_00758 5.3e-105 yetJ S Belongs to the BI1 family
LEMALOII_00759 5.4e-159 yetK EG EamA-like transporter family
LEMALOII_00760 6.4e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
LEMALOII_00761 7.8e-213 yetM CH FAD binding domain
LEMALOII_00762 3.6e-199 yetN S Protein of unknown function (DUF3900)
LEMALOII_00763 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
LEMALOII_00764 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
LEMALOII_00765 2.1e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
LEMALOII_00766 1.9e-172 yfnG 4.2.1.45 M dehydratase
LEMALOII_00767 3.8e-181 yfnF M Nucleotide-diphospho-sugar transferase
LEMALOII_00768 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
LEMALOII_00769 3.5e-190 yfnD M Nucleotide-diphospho-sugar transferase
LEMALOII_00770 2e-206 fsr P COG0477 Permeases of the major facilitator superfamily
LEMALOII_00771 7.8e-134 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
LEMALOII_00772 1.3e-241 yfnA E amino acid
LEMALOII_00773 2.8e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LEMALOII_00774 1.1e-113 yfmS NT chemotaxis protein
LEMALOII_00775 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LEMALOII_00776 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
LEMALOII_00777 2.8e-70 yfmP K transcriptional
LEMALOII_00778 1.5e-209 yfmO EGP Major facilitator Superfamily
LEMALOII_00779 1.9e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LEMALOII_00780 6.3e-202 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
LEMALOII_00781 7.5e-82 yfmK 2.3.1.128 K acetyltransferase
LEMALOII_00782 8.5e-190 yfmJ S N-terminal domain of oxidoreductase
LEMALOII_00783 7.7e-214 G Major Facilitator Superfamily
LEMALOII_00784 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
LEMALOII_00785 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
LEMALOII_00786 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEMALOII_00787 4.3e-170 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEMALOII_00788 3.4e-169 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
LEMALOII_00789 2.9e-24 S Protein of unknown function (DUF3212)
LEMALOII_00790 7.6e-58 yflT S Heat induced stress protein YflT
LEMALOII_00791 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
LEMALOII_00792 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
LEMALOII_00793 1e-290 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
LEMALOII_00794 8.9e-119 citT T response regulator
LEMALOII_00795 3e-181 yflP S Tripartite tricarboxylate transporter family receptor
LEMALOII_00797 8.5e-227 citM C Citrate transporter
LEMALOII_00798 5.5e-152 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
LEMALOII_00799 1.3e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
LEMALOII_00800 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
LEMALOII_00801 9e-124 yflK S protein conserved in bacteria
LEMALOII_00802 4e-18 yflJ S Protein of unknown function (DUF2639)
LEMALOII_00803 4.1e-19 yflI
LEMALOII_00804 2.4e-50 yflH S Protein of unknown function (DUF3243)
LEMALOII_00805 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
LEMALOII_00806 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
LEMALOII_00807 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
LEMALOII_00808 6e-67 yhdN S Domain of unknown function (DUF1992)
LEMALOII_00809 3.2e-256 agcS_1 E Sodium alanine symporter
LEMALOII_00810 1.6e-194 E Spore germination protein
LEMALOII_00812 5.1e-207 yfkR S spore germination
LEMALOII_00813 1.5e-283 yfkQ EG Spore germination protein
LEMALOII_00814 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LEMALOII_00815 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
LEMALOII_00816 1.8e-133 treR K transcriptional
LEMALOII_00817 1.6e-125 yfkO C nitroreductase
LEMALOII_00818 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
LEMALOII_00819 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
LEMALOII_00820 6.8e-207 ydiM EGP Major facilitator Superfamily
LEMALOII_00821 2.1e-29 yfkK S Belongs to the UPF0435 family
LEMALOII_00822 2.2e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LEMALOII_00823 8.4e-51 yfkI S gas vesicle protein
LEMALOII_00824 9.7e-144 yihY S Belongs to the UPF0761 family
LEMALOII_00825 5e-08
LEMALOII_00826 1.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
LEMALOII_00827 6.1e-183 cax P COG0387 Ca2 H antiporter
LEMALOII_00828 1.2e-146 yfkD S YfkD-like protein
LEMALOII_00829 6e-149 yfkC M Mechanosensitive ion channel
LEMALOII_00830 5.4e-222 yfkA S YfkB-like domain
LEMALOII_00831 1.1e-26 yfjT
LEMALOII_00832 2.6e-154 pdaA G deacetylase
LEMALOII_00833 4.2e-150 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
LEMALOII_00834 1.7e-184 corA P Mediates influx of magnesium ions
LEMALOII_00835 1e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LEMALOII_00836 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LEMALOII_00837 1.6e-39 S YfzA-like protein
LEMALOII_00838 5.1e-192 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LEMALOII_00839 3.9e-86 yfjM S Psort location Cytoplasmic, score
LEMALOII_00840 3e-29 yfjL
LEMALOII_00841 1.2e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LEMALOII_00842 1e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LEMALOII_00843 2.9e-197 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LEMALOII_00844 6.4e-257 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LEMALOII_00845 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
LEMALOII_00846 1.2e-25 sspH S Belongs to the SspH family
LEMALOII_00847 4e-56 yfjF S UPF0060 membrane protein
LEMALOII_00848 1.3e-80 S Family of unknown function (DUF5381)
LEMALOII_00849 1.8e-101 yfjD S Family of unknown function (DUF5381)
LEMALOII_00850 4.1e-144 yfjC
LEMALOII_00851 9.2e-191 yfjB
LEMALOII_00852 1.1e-44 yfjA S Belongs to the WXG100 family
LEMALOII_00853 9.9e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LEMALOII_00854 3.2e-141 glvR K Helix-turn-helix domain, rpiR family
LEMALOII_00855 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LEMALOII_00856 2.1e-310 yfiB3 V ABC transporter
LEMALOII_00857 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
LEMALOII_00858 9.8e-65 mhqP S DoxX
LEMALOII_00859 5.7e-163 yfiE 1.13.11.2 S glyoxalase
LEMALOII_00860 1.5e-177 K AraC-like ligand binding domain
LEMALOII_00861 1.8e-262 iolT EGP Major facilitator Superfamily
LEMALOII_00862 8.4e-184 G Xylose isomerase
LEMALOII_00863 1.1e-233 S Oxidoreductase
LEMALOII_00865 1.1e-214 yxjM T Histidine kinase
LEMALOII_00866 3.2e-113 KT LuxR family transcriptional regulator
LEMALOII_00867 6.2e-171 V ABC transporter, ATP-binding protein
LEMALOII_00868 9.8e-214 V ABC-2 family transporter protein
LEMALOII_00869 4.6e-208 V COG0842 ABC-type multidrug transport system, permease component
LEMALOII_00870 8.3e-99 padR K transcriptional
LEMALOII_00871 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
LEMALOII_00872 9e-198 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
LEMALOII_00873 2e-109 yfiR K Transcriptional regulator
LEMALOII_00874 5.1e-221 yfiS EGP Major facilitator Superfamily
LEMALOII_00875 3.3e-100 yfiT S Belongs to the metal hydrolase YfiT family
LEMALOII_00876 8.7e-287 yfiU EGP Major facilitator Superfamily
LEMALOII_00877 3.1e-81 yfiV K transcriptional
LEMALOII_00878 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LEMALOII_00879 6.2e-182 yfiY P ABC transporter substrate-binding protein
LEMALOII_00880 3.1e-176 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEMALOII_00881 5.2e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEMALOII_00882 1.8e-167 yfhB 5.3.3.17 S PhzF family
LEMALOII_00883 3.9e-107 yfhC C nitroreductase
LEMALOII_00884 2.1e-25 yfhD S YfhD-like protein
LEMALOII_00886 4.9e-173 yfhF S nucleoside-diphosphate sugar epimerase
LEMALOII_00887 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
LEMALOII_00888 9.7e-52 yfhH S Protein of unknown function (DUF1811)
LEMALOII_00890 1.1e-209 yfhI EGP Major facilitator Superfamily
LEMALOII_00891 6.2e-20 sspK S reproduction
LEMALOII_00892 1.3e-44 yfhJ S WVELL protein
LEMALOII_00893 9.2e-92 batE T Bacterial SH3 domain homologues
LEMALOII_00894 3.5e-51 yfhL S SdpI/YhfL protein family
LEMALOII_00895 6.7e-172 yfhM S Alpha beta hydrolase
LEMALOII_00896 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LEMALOII_00897 0.0 yfhO S Bacterial membrane protein YfhO
LEMALOII_00898 5.5e-186 yfhP S membrane-bound metal-dependent
LEMALOII_00899 7.8e-212 mutY L A G-specific
LEMALOII_00900 6.9e-36 yfhS
LEMALOII_00901 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEMALOII_00902 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
LEMALOII_00903 1.5e-37 ygaB S YgaB-like protein
LEMALOII_00904 1.3e-104 ygaC J Belongs to the UPF0374 family
LEMALOII_00905 1.8e-301 ygaD V ABC transporter
LEMALOII_00906 8.7e-180 ygaE S Membrane
LEMALOII_00907 1.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
LEMALOII_00908 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
LEMALOII_00909 4e-80 perR P Belongs to the Fur family
LEMALOII_00910 1.5e-56 ygzB S UPF0295 protein
LEMALOII_00911 6.7e-167 ygxA S Nucleotidyltransferase-like
LEMALOII_00912 3.4e-39 S COG NOG14552 non supervised orthologous group
LEMALOII_00917 7.8e-08
LEMALOII_00925 2e-08
LEMALOII_00929 2.7e-143 spo0M S COG4326 Sporulation control protein
LEMALOII_00930 3e-27
LEMALOII_00931 5.9e-134 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
LEMALOII_00932 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LEMALOII_00933 1.9e-266 ygaK C Berberine and berberine like
LEMALOII_00935 3.2e-291 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
LEMALOII_00936 1.1e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
LEMALOII_00937 1.7e-171 ssuA M Sulfonate ABC transporter
LEMALOII_00938 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
LEMALOII_00939 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
LEMALOII_00941 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LEMALOII_00942 4.1e-78 ygaO
LEMALOII_00943 4.4e-29 K Transcriptional regulator
LEMALOII_00945 7.9e-114 yhzB S B3/4 domain
LEMALOII_00946 2.1e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LEMALOII_00947 4.4e-177 yhbB S Putative amidase domain
LEMALOII_00948 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LEMALOII_00949 1.2e-109 yhbD K Protein of unknown function (DUF4004)
LEMALOII_00950 1.6e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
LEMALOII_00951 9.1e-74 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
LEMALOII_00952 0.0 prkA T Ser protein kinase
LEMALOII_00953 2.5e-225 yhbH S Belongs to the UPF0229 family
LEMALOII_00954 2.2e-76 yhbI K DNA-binding transcription factor activity
LEMALOII_00955 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
LEMALOII_00956 3.1e-271 yhcA EGP Major facilitator Superfamily
LEMALOII_00957 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
LEMALOII_00958 2.8e-37 yhcC
LEMALOII_00959 7.8e-55
LEMALOII_00960 6.6e-60 yhcF K Transcriptional regulator
LEMALOII_00961 1.6e-123 yhcG V ABC transporter, ATP-binding protein
LEMALOII_00962 2.6e-166 yhcH V ABC transporter, ATP-binding protein
LEMALOII_00963 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LEMALOII_00964 1e-30 cspB K Cold-shock protein
LEMALOII_00965 5.2e-153 metQ M Belongs to the nlpA lipoprotein family
LEMALOII_00966 1.2e-197 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
LEMALOII_00967 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LEMALOII_00968 3.7e-44 yhcM
LEMALOII_00969 2.1e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LEMALOII_00970 2.5e-167 yhcP
LEMALOII_00971 5.2e-100 yhcQ M Spore coat protein
LEMALOII_00972 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
LEMALOII_00973 7.6e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
LEMALOII_00974 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LEMALOII_00975 9.3e-68 yhcU S Family of unknown function (DUF5365)
LEMALOII_00976 9.9e-68 yhcV S COG0517 FOG CBS domain
LEMALOII_00977 4.6e-120 yhcW 5.4.2.6 S hydrolase
LEMALOII_00978 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LEMALOII_00979 1.1e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LEMALOII_00980 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LEMALOII_00981 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
LEMALOII_00982 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LEMALOII_00983 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LEMALOII_00984 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
LEMALOII_00985 5.5e-214 yhcY 2.7.13.3 T Histidine kinase
LEMALOII_00986 1.1e-113 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LEMALOII_00987 1.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
LEMALOII_00988 1.2e-38 yhdB S YhdB-like protein
LEMALOII_00989 4.8e-54 yhdC S Protein of unknown function (DUF3889)
LEMALOII_00990 7.9e-189 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
LEMALOII_00991 3.5e-76 nsrR K Transcriptional regulator
LEMALOII_00992 8.7e-239 ygxB M Conserved TM helix
LEMALOII_00993 2.1e-276 ycgB S Stage V sporulation protein R
LEMALOII_00994 5.8e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
LEMALOII_00995 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
LEMALOII_00996 3.8e-162 citR K Transcriptional regulator
LEMALOII_00997 1.4e-206 citA 2.3.3.1 C Belongs to the citrate synthase family
LEMALOII_00998 4.9e-162 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEMALOII_00999 3.4e-250 yhdG E amino acid
LEMALOII_01000 1.5e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
LEMALOII_01001 3.7e-276 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LEMALOII_01002 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LEMALOII_01003 8.1e-45 yhdK S Sigma-M inhibitor protein
LEMALOII_01004 6.6e-201 yhdL S Sigma factor regulator N-terminal
LEMALOII_01005 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
LEMALOII_01006 1.5e-191 yhdN C Aldo keto reductase
LEMALOII_01007 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
LEMALOII_01008 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
LEMALOII_01009 4.1e-74 cueR K transcriptional
LEMALOII_01010 1.4e-223 yhdR 2.6.1.1 E Aminotransferase
LEMALOII_01011 1.1e-240 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
LEMALOII_01012 2.8e-47 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LEMALOII_01013 5.1e-66 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LEMALOII_01014 3.3e-135 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LEMALOII_01016 6.6e-204 yhdY M Mechanosensitive ion channel
LEMALOII_01017 1.2e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
LEMALOII_01018 1.7e-151 yheN G deacetylase
LEMALOII_01019 1.1e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
LEMALOII_01020 2.2e-233 nhaC C Na H antiporter
LEMALOII_01021 3.4e-84 nhaX T Belongs to the universal stress protein A family
LEMALOII_01022 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
LEMALOII_01023 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
LEMALOII_01024 3.7e-111 yheG GM NAD(P)H-binding
LEMALOII_01025 6.3e-28 sspB S spore protein
LEMALOII_01026 1.3e-36 yheE S Family of unknown function (DUF5342)
LEMALOII_01027 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
LEMALOII_01028 4.3e-216 yheC HJ YheC/D like ATP-grasp
LEMALOII_01029 6.7e-204 yheB S Belongs to the UPF0754 family
LEMALOII_01030 9.5e-48 yheA S Belongs to the UPF0342 family
LEMALOII_01031 3.1e-206 yhaZ L DNA alkylation repair enzyme
LEMALOII_01032 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
LEMALOII_01033 7.1e-294 hemZ H coproporphyrinogen III oxidase
LEMALOII_01034 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
LEMALOII_01035 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
LEMALOII_01037 1.9e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
LEMALOII_01038 1.1e-26 S YhzD-like protein
LEMALOII_01039 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
LEMALOII_01040 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
LEMALOII_01041 3.6e-227 yhaO L DNA repair exonuclease
LEMALOII_01042 0.0 yhaN L AAA domain
LEMALOII_01043 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
LEMALOII_01044 1.6e-21 yhaL S Sporulation protein YhaL
LEMALOII_01045 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LEMALOII_01046 8.7e-90 yhaK S Putative zincin peptidase
LEMALOII_01047 1.3e-54 yhaI S Protein of unknown function (DUF1878)
LEMALOII_01048 1e-113 hpr K Negative regulator of protease production and sporulation
LEMALOII_01049 7e-39 yhaH S YtxH-like protein
LEMALOII_01050 3.6e-80 trpP S Tryptophan transporter TrpP
LEMALOII_01051 9.9e-205 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LEMALOII_01052 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
LEMALOII_01053 4.6e-137 ecsA V transporter (ATP-binding protein)
LEMALOII_01054 1.8e-215 ecsB U ABC transporter
LEMALOII_01055 4.8e-115 ecsC S EcsC protein family
LEMALOII_01056 2.3e-231 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
LEMALOII_01057 4.2e-248 yhfA C membrane
LEMALOII_01058 7.5e-17 1.15.1.2 C Rubrerythrin
LEMALOII_01059 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
LEMALOII_01060 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LEMALOII_01061 1.7e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LEMALOII_01062 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
LEMALOII_01063 1.7e-268 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LEMALOII_01064 1.4e-101 yhgD K Transcriptional regulator
LEMALOII_01065 1e-238 yhgE S YhgE Pip N-terminal domain protein
LEMALOII_01066 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LEMALOII_01067 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
LEMALOII_01068 1.6e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
LEMALOII_01069 1.7e-72 3.4.13.21 S ASCH
LEMALOII_01070 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LEMALOII_01071 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
LEMALOII_01072 2e-191 lplJ 6.3.1.20 H Lipoate-protein ligase
LEMALOII_01073 2.6e-112 yhfK GM NmrA-like family
LEMALOII_01074 7.3e-302 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
LEMALOII_01075 1.9e-65 yhfM
LEMALOII_01076 5.4e-242 yhfN 3.4.24.84 O Peptidase M48
LEMALOII_01077 2.3e-204 aprE 3.4.21.62 O Belongs to the peptidase S8 family
LEMALOII_01078 9.2e-80 VY92_01935 K acetyltransferase
LEMALOII_01079 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
LEMALOII_01080 4.3e-159 yfmC M Periplasmic binding protein
LEMALOII_01081 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
LEMALOII_01082 2.3e-201 vraB 2.3.1.9 I Belongs to the thiolase family
LEMALOII_01083 1e-281 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
LEMALOII_01084 5e-91 bioY S BioY family
LEMALOII_01085 1.7e-182 hemAT NT chemotaxis protein
LEMALOII_01086 1.1e-302 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
LEMALOII_01087 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEMALOII_01088 1.3e-32 yhzC S IDEAL
LEMALOII_01089 4.2e-109 comK K Competence transcription factor
LEMALOII_01090 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
LEMALOII_01091 7.8e-42 yhjA S Excalibur calcium-binding domain
LEMALOII_01092 6.1e-266 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LEMALOII_01093 6.9e-27 yhjC S Protein of unknown function (DUF3311)
LEMALOII_01094 5e-60 yhjD
LEMALOII_01095 9.1e-110 yhjE S SNARE associated Golgi protein
LEMALOII_01096 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
LEMALOII_01097 1.1e-286 yhjG CH FAD binding domain
LEMALOII_01098 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
LEMALOII_01099 6.9e-215 glcP G Major Facilitator Superfamily
LEMALOII_01100 1.1e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
LEMALOII_01101 1.8e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
LEMALOII_01102 4.4e-255 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
LEMALOII_01103 1.6e-188 yhjM 5.1.1.1 K Transcriptional regulator
LEMALOII_01104 3.8e-202 abrB S membrane
LEMALOII_01105 3.1e-215 EGP Transmembrane secretion effector
LEMALOII_01106 0.0 S Sugar transport-related sRNA regulator N-term
LEMALOII_01107 2e-36 yhjQ C COG1145 Ferredoxin
LEMALOII_01108 2.2e-78 yhjR S Rubrerythrin
LEMALOII_01109 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
LEMALOII_01110 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
LEMALOII_01111 1.7e-221 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
LEMALOII_01112 0.0 sbcC L COG0419 ATPase involved in DNA repair
LEMALOII_01113 6e-51 yisB V COG1403 Restriction endonuclease
LEMALOII_01114 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
LEMALOII_01115 3e-66 gerPE S Spore germination protein GerPE
LEMALOII_01116 6.3e-24 gerPD S Spore germination protein
LEMALOII_01117 1.8e-54 gerPC S Spore germination protein
LEMALOII_01118 4e-34 gerPB S cell differentiation
LEMALOII_01119 1.9e-33 gerPA S Spore germination protein
LEMALOII_01120 1.5e-22 yisI S Spo0E like sporulation regulatory protein
LEMALOII_01121 1.7e-176 cotH M Spore Coat
LEMALOII_01122 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
LEMALOII_01123 3e-57 yisL S UPF0344 protein
LEMALOII_01124 0.0 wprA O Belongs to the peptidase S8 family
LEMALOII_01125 7.2e-106 yisN S Protein of unknown function (DUF2777)
LEMALOII_01126 0.0 asnO 6.3.5.4 E Asparagine synthase
LEMALOII_01127 2.1e-88 yizA S Damage-inducible protein DinB
LEMALOII_01128 6.8e-150 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
LEMALOII_01129 4e-243 yisQ V Mate efflux family protein
LEMALOII_01130 1.2e-160 yisR K Transcriptional regulator
LEMALOII_01131 2.4e-184 purR K helix_turn _helix lactose operon repressor
LEMALOII_01132 4.5e-199 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
LEMALOII_01133 1.3e-93 yisT S DinB family
LEMALOII_01134 6.4e-108 argO S Lysine exporter protein LysE YggA
LEMALOII_01135 1.7e-281 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LEMALOII_01136 4e-36 mcbG S Pentapeptide repeats (9 copies)
LEMALOII_01137 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LEMALOII_01138 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
LEMALOII_01139 3.2e-233 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
LEMALOII_01140 9.2e-143 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
LEMALOII_01141 4.9e-125 comB 3.1.3.71 H Belongs to the ComB family
LEMALOII_01142 1.9e-141 yitD 4.4.1.19 S synthase
LEMALOII_01143 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LEMALOII_01144 5.4e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
LEMALOII_01145 4e-229 yitG EGP Major facilitator Superfamily
LEMALOII_01146 1.8e-161 yitH K Acetyltransferase (GNAT) domain
LEMALOII_01147 5.8e-82 yjcF S Acetyltransferase (GNAT) domain
LEMALOII_01148 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
LEMALOII_01149 8.6e-55 yajQ S Belongs to the UPF0234 family
LEMALOII_01150 4e-161 cvfB S protein conserved in bacteria
LEMALOII_01151 8.5e-94
LEMALOII_01152 2.8e-171
LEMALOII_01153 1.5e-97 S Sporulation delaying protein SdpA
LEMALOII_01154 1.5e-58 K Transcriptional regulator PadR-like family
LEMALOII_01155 2e-95
LEMALOII_01156 1.4e-44 yitR S Domain of unknown function (DUF3784)
LEMALOII_01157 2.2e-311 nprB 3.4.24.28 E Peptidase M4
LEMALOII_01158 8.4e-159 yitS S protein conserved in bacteria
LEMALOII_01159 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
LEMALOII_01160 1.9e-72 ipi S Intracellular proteinase inhibitor
LEMALOII_01161 1.2e-17 S Protein of unknown function (DUF3813)
LEMALOII_01162 1.9e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
LEMALOII_01163 4.5e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
LEMALOII_01164 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
LEMALOII_01165 1.5e-22 pilT S Proteolipid membrane potential modulator
LEMALOII_01166 4.3e-272 yitY C D-arabinono-1,4-lactone oxidase
LEMALOII_01167 1.7e-88 norB G Major Facilitator Superfamily
LEMALOII_01168 5.4e-200 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LEMALOII_01169 3.1e-231 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LEMALOII_01170 2.2e-137 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
LEMALOII_01171 4.4e-219 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
LEMALOII_01172 3.9e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
LEMALOII_01173 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
LEMALOII_01174 3.8e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LEMALOII_01175 9.5e-28 yjzC S YjzC-like protein
LEMALOII_01176 2.3e-16 yjzD S Protein of unknown function (DUF2929)
LEMALOII_01177 6.2e-142 yjaU I carboxylic ester hydrolase activity
LEMALOII_01178 7.3e-103 yjaV
LEMALOII_01179 1.1e-183 med S Transcriptional activator protein med
LEMALOII_01180 7.3e-26 comZ S ComZ
LEMALOII_01181 2.7e-22 yjzB
LEMALOII_01182 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LEMALOII_01183 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LEMALOII_01184 7.8e-151 yjaZ O Zn-dependent protease
LEMALOII_01185 1.8e-184 appD P Belongs to the ABC transporter superfamily
LEMALOII_01186 6.5e-187 appF E Belongs to the ABC transporter superfamily
LEMALOII_01187 1.6e-251 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
LEMALOII_01188 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEMALOII_01189 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEMALOII_01190 5e-147 yjbA S Belongs to the UPF0736 family
LEMALOII_01191 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
LEMALOII_01192 0.0 oppA E ABC transporter substrate-binding protein
LEMALOII_01193 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEMALOII_01194 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEMALOII_01195 3e-198 oppD P Belongs to the ABC transporter superfamily
LEMALOII_01196 5.5e-172 oppF E Belongs to the ABC transporter superfamily
LEMALOII_01197 8.6e-196 yjbB EGP Major Facilitator Superfamily
LEMALOII_01198 6.9e-104 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LEMALOII_01199 2.1e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LEMALOII_01200 6e-112 yjbE P Integral membrane protein TerC family
LEMALOII_01201 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
LEMALOII_01202 2.3e-223 yjbF S Competence protein
LEMALOII_01203 0.0 pepF E oligoendopeptidase F
LEMALOII_01204 1.8e-20
LEMALOII_01206 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
LEMALOII_01207 3.7e-72 yjbI S Bacterial-like globin
LEMALOII_01208 1.5e-87 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LEMALOII_01209 2.4e-101 yjbK S protein conserved in bacteria
LEMALOII_01210 7.1e-62 yjbL S Belongs to the UPF0738 family
LEMALOII_01211 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
LEMALOII_01212 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LEMALOII_01213 9.5e-161 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LEMALOII_01214 3e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
LEMALOII_01215 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LEMALOII_01216 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LEMALOII_01217 3.8e-108 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
LEMALOII_01218 7.2e-219 thiO 1.4.3.19 E Glycine oxidase
LEMALOII_01219 3e-30 thiS H thiamine diphosphate biosynthetic process
LEMALOII_01220 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
LEMALOII_01221 6e-188 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LEMALOII_01222 5.3e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
LEMALOII_01223 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
LEMALOII_01224 5.9e-54 yjbX S Spore coat protein
LEMALOII_01225 5.2e-83 cotZ S Spore coat protein
LEMALOII_01226 3.4e-96 cotY S Spore coat protein Z
LEMALOII_01227 6.4e-77 cotX S Spore Coat Protein X and V domain
LEMALOII_01228 3e-32 cotW
LEMALOII_01229 2.3e-55 cotV S Spore Coat Protein X and V domain
LEMALOII_01230 8.7e-57 yjcA S Protein of unknown function (DUF1360)
LEMALOII_01233 2.9e-38 spoVIF S Stage VI sporulation protein F
LEMALOII_01234 0.0 yjcD 3.6.4.12 L DNA helicase
LEMALOII_01235 1.7e-38
LEMALOII_01236 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LEMALOII_01237 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
LEMALOII_01238 1.8e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
LEMALOII_01239 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
LEMALOII_01240 2.9e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
LEMALOII_01241 3.7e-99 rimJ 2.3.1.128 J Alanine acetyltransferase
LEMALOII_01242 1.1e-212 yjcL S Protein of unknown function (DUF819)
LEMALOII_01245 2.1e-190 S Putative amidase domain
LEMALOII_01246 2.6e-44 yjcN
LEMALOII_01249 8.5e-81 L Transposase
LEMALOII_01250 1.6e-72 yjcP
LEMALOII_01251 4.1e-49 S YjcQ protein
LEMALOII_01252 1.1e-92 yqaS L DNA packaging
LEMALOII_01253 2.2e-47 yjcS S Antibiotic biosynthesis monooxygenase
LEMALOII_01254 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
LEMALOII_01256 1.3e-264 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
LEMALOII_01257 5.6e-65 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
LEMALOII_01258 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
LEMALOII_01259 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
LEMALOII_01260 4.8e-51 yjdF S Protein of unknown function (DUF2992)
LEMALOII_01261 2.5e-94 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
LEMALOII_01263 8e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LEMALOII_01264 4.2e-29 S Domain of unknown function (DUF4177)
LEMALOII_01265 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
LEMALOII_01266 3.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
LEMALOII_01268 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
LEMALOII_01269 5.5e-83 S Protein of unknown function (DUF2690)
LEMALOII_01270 3.6e-21 yjfB S Putative motility protein
LEMALOII_01271 1.6e-171 yjfC O Predicted Zn-dependent protease (DUF2268)
LEMALOII_01272 1.2e-45 T PhoQ Sensor
LEMALOII_01273 8.9e-104 yjgB S Domain of unknown function (DUF4309)
LEMALOII_01274 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
LEMALOII_01275 4.3e-95 yjgD S Protein of unknown function (DUF1641)
LEMALOII_01276 8.7e-07 S Domain of unknown function (DUF4352)
LEMALOII_01277 2e-117 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
LEMALOII_01279 3.8e-226 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
LEMALOII_01280 4.5e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
LEMALOII_01281 8.2e-30
LEMALOII_01282 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
LEMALOII_01283 1.9e-122 ybbM S transport system, permease component
LEMALOII_01284 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
LEMALOII_01285 1.8e-176 yjlA EG Putative multidrug resistance efflux transporter
LEMALOII_01286 2.8e-93 yjlB S Cupin domain
LEMALOII_01287 7.1e-66 yjlC S Protein of unknown function (DUF1641)
LEMALOII_01288 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
LEMALOII_01289 6.3e-284 uxaC 5.3.1.12 G glucuronate isomerase
LEMALOII_01290 5.8e-250 yjmB G symporter YjmB
LEMALOII_01291 3e-195 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
LEMALOII_01292 1.6e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
LEMALOII_01293 4.7e-215 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
LEMALOII_01294 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LEMALOII_01295 3.7e-227 exuT G Sugar (and other) transporter
LEMALOII_01296 2.3e-184 exuR K transcriptional
LEMALOII_01297 2.1e-287 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
LEMALOII_01298 2e-288 uxaA 4.2.1.7, 4.4.1.24 G Altronate
LEMALOII_01299 4.3e-130 MA20_18170 S membrane transporter protein
LEMALOII_01300 3.3e-80 yjoA S DinB family
LEMALOII_01301 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
LEMALOII_01302 2.1e-213 S response regulator aspartate phosphatase
LEMALOII_01304 6.3e-41 S YCII-related domain
LEMALOII_01305 9.1e-170 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
LEMALOII_01306 2.1e-61 yjqA S Bacterial PH domain
LEMALOII_01307 4.2e-112 yjqB S Pfam:DUF867
LEMALOII_01308 4.4e-160 ydbD P Catalase
LEMALOII_01309 1.6e-111 xkdA E IrrE N-terminal-like domain
LEMALOII_01310 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
LEMALOII_01312 5.9e-157 xkdB K sequence-specific DNA binding
LEMALOII_01313 6.4e-119 xkdC L Bacterial dnaA protein
LEMALOII_01316 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
LEMALOII_01317 4.4e-86 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
LEMALOII_01318 4.8e-140 xtmA L phage terminase small subunit
LEMALOII_01319 9.6e-255 xtmB S phage terminase, large subunit
LEMALOII_01320 5.4e-286 yqbA S portal protein
LEMALOII_01321 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
LEMALOII_01322 5.8e-169 xkdG S Phage capsid family
LEMALOII_01323 5.5e-65 yqbG S Protein of unknown function (DUF3199)
LEMALOII_01324 8.7e-65 yqbH S Domain of unknown function (DUF3599)
LEMALOII_01325 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
LEMALOII_01326 1.9e-77 xkdJ
LEMALOII_01327 2.5e-256 xkdK S Phage tail sheath C-terminal domain
LEMALOII_01328 6.1e-76 xkdM S Phage tail tube protein
LEMALOII_01329 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
LEMALOII_01330 0.0 xkdO L Transglycosylase SLT domain
LEMALOII_01331 3.7e-122 xkdP S Lysin motif
LEMALOII_01332 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
LEMALOII_01333 2.1e-39 xkdR S Protein of unknown function (DUF2577)
LEMALOII_01334 9.6e-71 xkdS S Protein of unknown function (DUF2634)
LEMALOII_01335 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
LEMALOII_01336 4e-104 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
LEMALOII_01337 6.7e-41
LEMALOII_01338 0.0
LEMALOII_01339 2.6e-55 xkdW S XkdW protein
LEMALOII_01340 1.7e-23 xkdX
LEMALOII_01341 1.2e-154 xepA
LEMALOII_01342 2.8e-39 xhlA S Haemolysin XhlA
LEMALOII_01343 9.3e-40 xhlB S SPP1 phage holin
LEMALOII_01344 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LEMALOII_01345 6.7e-23 spoIISB S Stage II sporulation protein SB
LEMALOII_01346 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
LEMALOII_01347 5.8e-175 pit P phosphate transporter
LEMALOII_01348 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
LEMALOII_01349 9.4e-242 steT E amino acid
LEMALOII_01350 7.2e-183 mhqA E COG0346 Lactoylglutathione lyase and related lyases
LEMALOII_01352 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LEMALOII_01353 1.3e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LEMALOII_01355 8.5e-214 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LEMALOII_01356 1e-137 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
LEMALOII_01357 7.9e-154 dppA E D-aminopeptidase
LEMALOII_01358 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEMALOII_01359 3.9e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEMALOII_01360 3.4e-191 dppD P Belongs to the ABC transporter superfamily
LEMALOII_01361 0.0 dppE E ABC transporter substrate-binding protein
LEMALOII_01363 8.1e-179 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
LEMALOII_01364 3.2e-203 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
LEMALOII_01365 5.3e-172 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
LEMALOII_01366 7.7e-188 ykfD E Belongs to the ABC transporter superfamily
LEMALOII_01367 7.4e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
LEMALOII_01368 5.3e-161 ykgA E Amidinotransferase
LEMALOII_01369 1.5e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
LEMALOII_01370 1e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LEMALOII_01371 1e-07
LEMALOII_01372 5.4e-130 ykjA S Protein of unknown function (DUF421)
LEMALOII_01373 1e-98 ykkA S Protein of unknown function (DUF664)
LEMALOII_01374 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LEMALOII_01375 3.5e-55 ykkC P Multidrug resistance protein
LEMALOII_01376 1.1e-50 ykkD P Multidrug resistance protein
LEMALOII_01377 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
LEMALOII_01378 1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LEMALOII_01379 2.5e-228 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LEMALOII_01380 1.3e-70 ohrA O Organic hydroperoxide resistance protein
LEMALOII_01381 3.9e-75 ohrR K COG1846 Transcriptional regulators
LEMALOII_01382 8.4e-72 ohrB O Organic hydroperoxide resistance protein
LEMALOII_01384 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
LEMALOII_01385 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LEMALOII_01386 1.7e-176 isp O Belongs to the peptidase S8 family
LEMALOII_01387 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LEMALOII_01388 1.8e-136 ykoC P Cobalt transport protein
LEMALOII_01389 4.6e-311 P ABC transporter, ATP-binding protein
LEMALOII_01390 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
LEMALOII_01391 7.9e-111 ykoF S YKOF-related Family
LEMALOII_01392 2.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEMALOII_01393 9.4e-245 ykoH 2.7.13.3 T Histidine kinase
LEMALOII_01394 1.1e-113 ykoI S Peptidase propeptide and YPEB domain
LEMALOII_01395 4.4e-86 ykoJ S Peptidase propeptide and YPEB domain
LEMALOII_01398 2.2e-222 mgtE P Acts as a magnesium transporter
LEMALOII_01399 1.4e-53 tnrA K transcriptional
LEMALOII_01400 5.9e-18
LEMALOII_01401 6.9e-26 ykoL
LEMALOII_01402 1.3e-81 mhqR K transcriptional
LEMALOII_01403 2.3e-220 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
LEMALOII_01404 3.7e-99 ykoP G polysaccharide deacetylase
LEMALOII_01405 7.1e-155 ykoQ S Calcineurin-like phosphoesterase superfamily domain
LEMALOII_01406 0.0 ykoS
LEMALOII_01407 2.5e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LEMALOII_01408 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
LEMALOII_01409 3.2e-161 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LEMALOII_01410 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
LEMALOII_01411 1.4e-116 ykoX S membrane-associated protein
LEMALOII_01412 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
LEMALOII_01413 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEMALOII_01414 8.2e-117 rsgI S Anti-sigma factor N-terminus
LEMALOII_01415 1.9e-26 sspD S small acid-soluble spore protein
LEMALOII_01416 1.5e-124 ykrK S Domain of unknown function (DUF1836)
LEMALOII_01417 7e-156 htpX O Belongs to the peptidase M48B family
LEMALOII_01418 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
LEMALOII_01419 1.2e-10 ydfR S Protein of unknown function (DUF421)
LEMALOII_01420 4.5e-22 ykzE
LEMALOII_01421 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
LEMALOII_01422 0.0 kinE 2.7.13.3 T Histidine kinase
LEMALOII_01423 7e-89 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LEMALOII_01425 3.3e-197 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LEMALOII_01426 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
LEMALOII_01427 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LEMALOII_01428 8e-232 mtnE 2.6.1.83 E Aminotransferase
LEMALOII_01429 4.1e-231 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
LEMALOII_01430 7.5e-137 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
LEMALOII_01431 7.2e-115 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
LEMALOII_01432 1.3e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LEMALOII_01433 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
LEMALOII_01434 6.4e-09 S Spo0E like sporulation regulatory protein
LEMALOII_01435 1.4e-64 eag
LEMALOII_01436 2.5e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
LEMALOII_01437 1.3e-75 ykvE K transcriptional
LEMALOII_01438 2.5e-125 motB N Flagellar motor protein
LEMALOII_01439 2.7e-138 motA N flagellar motor
LEMALOII_01440 0.0 clpE O Belongs to the ClpA ClpB family
LEMALOII_01441 8.7e-182 ykvI S membrane
LEMALOII_01442 7.3e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LEMALOII_01443 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
LEMALOII_01444 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
LEMALOII_01445 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LEMALOII_01446 2e-61 ykvN K Transcriptional regulator
LEMALOII_01447 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
LEMALOII_01448 4e-217 ykvP 3.5.1.28 M Glycosyl transferases group 1
LEMALOII_01449 1.2e-35 3.5.1.104 M LysM domain
LEMALOII_01450 8.5e-133 G Glycosyl hydrolases family 18
LEMALOII_01451 5.6e-46 ykvR S Protein of unknown function (DUF3219)
LEMALOII_01452 6e-25 ykvS S protein conserved in bacteria
LEMALOII_01453 2.8e-28
LEMALOII_01454 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
LEMALOII_01455 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LEMALOII_01456 4.9e-90 stoA CO thiol-disulfide
LEMALOII_01457 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
LEMALOII_01458 3.8e-09
LEMALOII_01459 8.7e-209 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
LEMALOII_01461 9.8e-180 ykvZ 5.1.1.1 K Transcriptional regulator
LEMALOII_01463 4.5e-128 glcT K antiterminator
LEMALOII_01464 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LEMALOII_01465 2.1e-39 ptsH G phosphocarrier protein HPr
LEMALOII_01466 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LEMALOII_01467 7.2e-39 splA S Transcriptional regulator
LEMALOII_01468 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
LEMALOII_01469 1.2e-131 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LEMALOII_01470 2e-264 mcpC NT chemotaxis protein
LEMALOII_01471 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
LEMALOII_01472 8e-124 ykwD J protein with SCP PR1 domains
LEMALOII_01473 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
LEMALOII_01474 0.0 pilS 2.7.13.3 T Histidine kinase
LEMALOII_01475 8e-224 patA 2.6.1.1 E Aminotransferase
LEMALOII_01476 2.2e-15
LEMALOII_01477 1.6e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
LEMALOII_01478 1.7e-84 ykyB S YkyB-like protein
LEMALOII_01479 1.6e-238 ykuC EGP Major facilitator Superfamily
LEMALOII_01480 4.6e-88 ykuD S protein conserved in bacteria
LEMALOII_01481 9.4e-166 ykuE S Metallophosphoesterase
LEMALOII_01482 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEMALOII_01483 0.0 3.2.1.132 M Putative peptidoglycan binding domain
LEMALOII_01484 1.7e-93 M Peptidoglycan-binding domain 1 protein
LEMALOII_01486 5.2e-234 ykuI T Diguanylate phosphodiesterase
LEMALOII_01487 3.9e-37 ykuJ S protein conserved in bacteria
LEMALOII_01488 4.4e-94 ykuK S Ribonuclease H-like
LEMALOII_01489 3.9e-27 ykzF S Antirepressor AbbA
LEMALOII_01490 1.6e-76 ykuL S CBS domain
LEMALOII_01491 3.5e-168 ccpC K Transcriptional regulator
LEMALOII_01492 5.7e-88 fld C Flavodoxin domain
LEMALOII_01493 3.2e-177 ykuO
LEMALOII_01494 3.2e-80 fld C Flavodoxin
LEMALOII_01495 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LEMALOII_01496 5.8e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LEMALOII_01497 9e-37 ykuS S Belongs to the UPF0180 family
LEMALOII_01498 8.8e-142 ykuT M Mechanosensitive ion channel
LEMALOII_01499 3.9e-101 ykuU O Alkyl hydroperoxide reductase
LEMALOII_01500 4.4e-82 ykuV CO thiol-disulfide
LEMALOII_01501 5.8e-95 rok K Repressor of ComK
LEMALOII_01502 2.9e-147 yknT
LEMALOII_01503 3.9e-110 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
LEMALOII_01504 5.3e-192 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LEMALOII_01505 8.1e-246 moeA 2.10.1.1 H molybdopterin
LEMALOII_01506 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
LEMALOII_01507 8.5e-84 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
LEMALOII_01508 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LEMALOII_01509 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
LEMALOII_01510 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
LEMALOII_01511 1e-117 yknW S Yip1 domain
LEMALOII_01512 3e-159 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LEMALOII_01513 2.5e-124 macB V ABC transporter, ATP-binding protein
LEMALOII_01514 2.1e-211 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
LEMALOII_01515 3.1e-136 fruR K Transcriptional regulator
LEMALOII_01516 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
LEMALOII_01517 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
LEMALOII_01518 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
LEMALOII_01519 8.1e-39 ykoA
LEMALOII_01520 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LEMALOII_01521 1.5e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LEMALOII_01522 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
LEMALOII_01523 1.1e-12 S Uncharacterized protein YkpC
LEMALOII_01524 7.7e-183 mreB D Rod-share determining protein MreBH
LEMALOII_01525 1.5e-43 abrB K of stationary sporulation gene expression
LEMALOII_01526 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
LEMALOII_01527 1.6e-162 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
LEMALOII_01528 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
LEMALOII_01529 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LEMALOII_01530 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LEMALOII_01531 8.2e-31 ykzG S Belongs to the UPF0356 family
LEMALOII_01532 1.4e-147 ykrA S hydrolases of the HAD superfamily
LEMALOII_01533 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LEMALOII_01535 2e-115 recN L Putative cell-wall binding lipoprotein
LEMALOII_01536 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LEMALOII_01537 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LEMALOII_01538 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LEMALOII_01539 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LEMALOII_01540 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
LEMALOII_01541 3.5e-277 speA 4.1.1.19 E Arginine
LEMALOII_01542 1.6e-42 yktA S Belongs to the UPF0223 family
LEMALOII_01543 7.1e-118 yktB S Belongs to the UPF0637 family
LEMALOII_01544 7.1e-26 ykzI
LEMALOII_01545 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
LEMALOII_01546 6.9e-78 ykzC S Acetyltransferase (GNAT) family
LEMALOII_01547 6.5e-173 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LEMALOII_01548 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
LEMALOII_01549 0.0 ylaA
LEMALOII_01550 2.7e-42 ylaB
LEMALOII_01551 2.7e-91 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
LEMALOII_01552 1.2e-11 sigC S Putative zinc-finger
LEMALOII_01553 1.8e-38 ylaE
LEMALOII_01554 8.2e-22 S Family of unknown function (DUF5325)
LEMALOII_01555 0.0 typA T GTP-binding protein TypA
LEMALOII_01556 4.2e-47 ylaH S YlaH-like protein
LEMALOII_01557 2.5e-32 ylaI S protein conserved in bacteria
LEMALOII_01558 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LEMALOII_01559 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
LEMALOII_01560 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LEMALOII_01561 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
LEMALOII_01562 8.7e-44 ylaN S Belongs to the UPF0358 family
LEMALOII_01563 4.5e-214 ftsW D Belongs to the SEDS family
LEMALOII_01564 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LEMALOII_01565 2.6e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
LEMALOII_01566 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
LEMALOII_01567 6.2e-191 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
LEMALOII_01568 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LEMALOII_01569 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
LEMALOII_01570 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
LEMALOII_01571 3e-167 ctaG S cytochrome c oxidase
LEMALOII_01572 7e-62 ylbA S YugN-like family
LEMALOII_01573 9.8e-74 ylbB T COG0517 FOG CBS domain
LEMALOII_01574 3e-201 ylbC S protein with SCP PR1 domains
LEMALOII_01575 4.1e-63 ylbD S Putative coat protein
LEMALOII_01576 6.7e-37 ylbE S YlbE-like protein
LEMALOII_01577 1.8e-75 ylbF S Belongs to the UPF0342 family
LEMALOII_01578 7.5e-39 ylbG S UPF0298 protein
LEMALOII_01579 1.9e-98 rsmD 2.1.1.171 L Methyltransferase
LEMALOII_01580 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LEMALOII_01581 3.8e-221 ylbJ S Sporulation integral membrane protein YlbJ
LEMALOII_01582 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
LEMALOII_01583 6.8e-187 ylbL T Belongs to the peptidase S16 family
LEMALOII_01584 2.8e-235 ylbM S Belongs to the UPF0348 family
LEMALOII_01586 1.3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
LEMALOII_01587 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
LEMALOII_01588 6.8e-75 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
LEMALOII_01589 4e-89 ylbP K n-acetyltransferase
LEMALOII_01590 7.3e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LEMALOII_01591 2.9e-309 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
LEMALOII_01592 2.9e-78 mraZ K Belongs to the MraZ family
LEMALOII_01593 6.6e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LEMALOII_01594 3.7e-44 ftsL D Essential cell division protein
LEMALOII_01595 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
LEMALOII_01596 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
LEMALOII_01597 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LEMALOII_01598 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LEMALOII_01599 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LEMALOII_01600 5.7e-186 spoVE D Belongs to the SEDS family
LEMALOII_01601 2.3e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LEMALOII_01602 5.3e-167 murB 1.3.1.98 M cell wall formation
LEMALOII_01603 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LEMALOII_01604 2.4e-103 ylxW S protein conserved in bacteria
LEMALOII_01605 1e-102 ylxX S protein conserved in bacteria
LEMALOII_01606 6.2e-58 sbp S small basic protein
LEMALOII_01607 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LEMALOII_01608 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LEMALOII_01609 0.0 bpr O COG1404 Subtilisin-like serine proteases
LEMALOII_01610 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
LEMALOII_01611 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEMALOII_01612 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEMALOII_01613 1.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
LEMALOII_01614 1.3e-256 argE 3.5.1.16 E Acetylornithine deacetylase
LEMALOII_01615 2.4e-37 ylmC S sporulation protein
LEMALOII_01616 1.1e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
LEMALOII_01617 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LEMALOII_01618 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LEMALOII_01619 1.3e-39 yggT S membrane
LEMALOII_01620 6.7e-139 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
LEMALOII_01621 2.6e-67 divIVA D Cell division initiation protein
LEMALOII_01622 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LEMALOII_01623 1.3e-63 dksA T COG1734 DnaK suppressor protein
LEMALOII_01624 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LEMALOII_01625 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LEMALOII_01626 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LEMALOII_01627 9e-232 pyrP F Xanthine uracil
LEMALOII_01628 1.4e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
LEMALOII_01629 1.7e-251 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LEMALOII_01630 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
LEMALOII_01631 0.0 carB 6.3.5.5 F Belongs to the CarB family
LEMALOII_01632 4.8e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
LEMALOII_01633 2.9e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LEMALOII_01634 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LEMALOII_01635 2.9e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LEMALOII_01637 3.5e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
LEMALOII_01638 1.1e-179 cysP P phosphate transporter
LEMALOII_01639 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
LEMALOII_01640 7.3e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
LEMALOII_01641 2.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
LEMALOII_01642 2e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
LEMALOII_01643 4.3e-83 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
LEMALOII_01644 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
LEMALOII_01645 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
LEMALOII_01646 2.4e-156 yloC S stress-induced protein
LEMALOII_01647 1.5e-40 ylzA S Belongs to the UPF0296 family
LEMALOII_01648 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
LEMALOII_01649 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LEMALOII_01650 8.8e-226 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LEMALOII_01651 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LEMALOII_01652 6e-85 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LEMALOII_01653 3.8e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LEMALOII_01654 2.9e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LEMALOII_01655 4.8e-207 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
LEMALOII_01656 2.4e-141 stp 3.1.3.16 T phosphatase
LEMALOII_01657 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
LEMALOII_01658 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LEMALOII_01659 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
LEMALOII_01660 3.1e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
LEMALOII_01661 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
LEMALOII_01662 5.5e-59 asp S protein conserved in bacteria
LEMALOII_01663 2.7e-302 yloV S kinase related to dihydroxyacetone kinase
LEMALOII_01664 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
LEMALOII_01665 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
LEMALOII_01666 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LEMALOII_01667 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
LEMALOII_01668 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LEMALOII_01669 9.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
LEMALOII_01670 6.1e-129 IQ reductase
LEMALOII_01671 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
LEMALOII_01672 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LEMALOII_01673 0.0 smc D Required for chromosome condensation and partitioning
LEMALOII_01674 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LEMALOII_01675 2.9e-87
LEMALOII_01676 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LEMALOII_01677 6e-236 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LEMALOII_01678 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
LEMALOII_01679 1.2e-36 ylqC S Belongs to the UPF0109 family
LEMALOII_01680 1.3e-61 ylqD S YlqD protein
LEMALOII_01681 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LEMALOII_01682 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
LEMALOII_01683 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LEMALOII_01684 4.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LEMALOII_01685 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LEMALOII_01686 8.5e-291 ylqG
LEMALOII_01687 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
LEMALOII_01688 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
LEMALOII_01689 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LEMALOII_01690 1.7e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
LEMALOII_01691 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LEMALOII_01692 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LEMALOII_01693 2.5e-169 xerC L tyrosine recombinase XerC
LEMALOII_01694 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LEMALOII_01695 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LEMALOII_01696 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LEMALOII_01697 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
LEMALOII_01698 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
LEMALOII_01699 1.9e-31 fliE N Flagellar hook-basal body
LEMALOII_01700 2.4e-255 fliF N The M ring may be actively involved in energy transduction
LEMALOII_01701 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
LEMALOII_01702 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
LEMALOII_01703 2.5e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
LEMALOII_01704 1.5e-69 fliJ N Flagellar biosynthesis chaperone
LEMALOII_01705 7.7e-37 ylxF S MgtE intracellular N domain
LEMALOII_01706 1.2e-221 fliK N Flagellar hook-length control protein
LEMALOII_01707 1.7e-72 flgD N Flagellar basal body rod modification protein
LEMALOII_01708 8.2e-140 flgG N Flagellar basal body rod
LEMALOII_01709 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
LEMALOII_01710 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
LEMALOII_01711 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LEMALOII_01712 1.6e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
LEMALOII_01713 9.3e-97 fliZ N Flagellar biosynthesis protein, FliO
LEMALOII_01714 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
LEMALOII_01715 2.2e-36 fliQ N Role in flagellar biosynthesis
LEMALOII_01716 3.6e-132 fliR N Flagellar biosynthetic protein FliR
LEMALOII_01717 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LEMALOII_01718 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LEMALOII_01719 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
LEMALOII_01720 4.8e-157 flhG D Belongs to the ParA family
LEMALOII_01721 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
LEMALOII_01722 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
LEMALOII_01723 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
LEMALOII_01724 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
LEMALOII_01725 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
LEMALOII_01726 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEMALOII_01727 4.3e-78 ylxL
LEMALOII_01728 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
LEMALOII_01729 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LEMALOII_01730 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
LEMALOII_01731 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LEMALOII_01732 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LEMALOII_01733 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
LEMALOII_01734 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
LEMALOII_01735 7.7e-233 rasP M zinc metalloprotease
LEMALOII_01736 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LEMALOII_01737 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LEMALOII_01738 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
LEMALOII_01739 1.1e-203 nusA K Participates in both transcription termination and antitermination
LEMALOII_01740 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
LEMALOII_01741 3.1e-47 ylxQ J ribosomal protein
LEMALOII_01742 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LEMALOII_01743 3e-44 ylxP S protein conserved in bacteria
LEMALOII_01744 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LEMALOII_01745 1.3e-173 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LEMALOII_01746 6.1e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
LEMALOII_01747 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LEMALOII_01748 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
LEMALOII_01749 4.2e-183 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
LEMALOII_01750 4.4e-233 pepR S Belongs to the peptidase M16 family
LEMALOII_01751 2.6e-42 ymxH S YlmC YmxH family
LEMALOII_01752 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
LEMALOII_01753 4.3e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
LEMALOII_01754 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LEMALOII_01755 5.9e-222 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
LEMALOII_01756 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LEMALOII_01757 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LEMALOII_01758 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
LEMALOII_01759 4.4e-32 S YlzJ-like protein
LEMALOII_01760 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
LEMALOII_01761 1.4e-133 ymfC K Transcriptional regulator
LEMALOII_01762 1.5e-206 ymfD EGP Major facilitator Superfamily
LEMALOII_01763 2.9e-235 ymfF S Peptidase M16
LEMALOII_01764 1.4e-242 ymfH S zinc protease
LEMALOII_01765 9.2e-130 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
LEMALOII_01766 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
LEMALOII_01767 2.7e-143 ymfK S Protein of unknown function (DUF3388)
LEMALOII_01768 1.9e-124 ymfM S protein conserved in bacteria
LEMALOII_01769 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LEMALOII_01770 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
LEMALOII_01771 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LEMALOII_01772 1e-215 pbpX V Beta-lactamase
LEMALOII_01773 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
LEMALOII_01774 1.9e-152 ymdB S protein conserved in bacteria
LEMALOII_01775 1.2e-36 spoVS S Stage V sporulation protein S
LEMALOII_01776 2.7e-199 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
LEMALOII_01777 6.5e-218 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
LEMALOII_01778 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LEMALOII_01779 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
LEMALOII_01780 2.2e-88 cotE S Spore coat protein
LEMALOII_01781 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LEMALOII_01782 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LEMALOII_01783 2.3e-70 S Regulatory protein YrvL
LEMALOII_01785 1.2e-97 ymcC S Membrane
LEMALOII_01786 4.4e-109 pksA K Transcriptional regulator
LEMALOII_01787 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
LEMALOII_01788 2.6e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
LEMALOII_01789 2.4e-186 pksD Q Acyl transferase domain
LEMALOII_01790 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
LEMALOII_01791 1.4e-37 acpK IQ Phosphopantetheine attachment site
LEMALOII_01792 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LEMALOII_01793 1.3e-245 pksG 2.3.3.10 I synthase
LEMALOII_01794 2.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
LEMALOII_01795 2.7e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
LEMALOII_01796 0.0 rhiB IQ polyketide synthase
LEMALOII_01797 0.0 pfaA Q Polyketide synthase of type I
LEMALOII_01798 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
LEMALOII_01799 0.0 dhbF IQ polyketide synthase
LEMALOII_01800 0.0 pks13 HQ Beta-ketoacyl synthase
LEMALOII_01801 2.5e-233 cypA C Cytochrome P450
LEMALOII_01802 1.2e-61 ymzB
LEMALOII_01803 6.6e-164 ymaE S Metallo-beta-lactamase superfamily
LEMALOII_01804 4.6e-252 aprX O Belongs to the peptidase S8 family
LEMALOII_01805 2.1e-126 ymaC S Replication protein
LEMALOII_01806 5.4e-80 ymaD O redox protein, regulator of disulfide bond formation
LEMALOII_01807 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
LEMALOII_01808 4.9e-51 ebrA P Small Multidrug Resistance protein
LEMALOII_01810 2.1e-46 ymaF S YmaF family
LEMALOII_01811 9.3e-175 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LEMALOII_01812 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
LEMALOII_01813 6.3e-23
LEMALOII_01814 4.5e-22 ymzA
LEMALOII_01815 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
LEMALOII_01816 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LEMALOII_01817 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LEMALOII_01818 2e-109 ymaB
LEMALOII_01819 8e-116 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LEMALOII_01820 1.7e-176 spoVK O stage V sporulation protein K
LEMALOII_01821 5.5e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LEMALOII_01822 3.3e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
LEMALOII_01823 1.1e-68 glnR K transcriptional
LEMALOII_01824 7e-261 glnA 6.3.1.2 E glutamine synthetase
LEMALOII_01825 5e-10
LEMALOII_01826 2.5e-32
LEMALOII_01827 5.8e-39
LEMALOII_01828 6.8e-80 G regulation of fungal-type cell wall biogenesis
LEMALOII_01829 4.9e-145 ynaC
LEMALOII_01830 2e-99 ynaD J Acetyltransferase (GNAT) domain
LEMALOII_01831 1.9e-123 ynaE S Domain of unknown function (DUF3885)
LEMALOII_01832 6.4e-60 ynaF
LEMALOII_01835 1.1e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
LEMALOII_01836 2.7e-255 xynT G MFS/sugar transport protein
LEMALOII_01837 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
LEMALOII_01838 1e-215 xylR GK ROK family
LEMALOII_01839 4e-264 xylA 5.3.1.5 G Belongs to the xylose isomerase family
LEMALOII_01840 6e-293 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
LEMALOII_01841 1.4e-113 yokF 3.1.31.1 L RNA catabolic process
LEMALOII_01842 3.5e-247 iolT EGP Major facilitator Superfamily
LEMALOII_01843 2.7e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LEMALOII_01844 6.3e-84 yncE S Protein of unknown function (DUF2691)
LEMALOII_01845 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
LEMALOII_01846 5.2e-15
LEMALOII_01849 1.2e-165 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LEMALOII_01851 1.3e-134 S Domain of unknown function, YrpD
LEMALOII_01854 7.9e-25 tatA U protein secretion
LEMALOII_01855 1.8e-71
LEMALOII_01856 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
LEMALOII_01859 5.7e-286 gerAA EG Spore germination protein
LEMALOII_01860 4.5e-197 gerAB U Spore germination
LEMALOII_01861 4.2e-220 gerLC S Spore germination protein
LEMALOII_01862 7.7e-154 yndG S DoxX-like family
LEMALOII_01863 2.6e-117 yndH S Domain of unknown function (DUF4166)
LEMALOII_01864 0.0 yndJ S YndJ-like protein
LEMALOII_01866 8.6e-139 yndL S Replication protein
LEMALOII_01867 5.8e-74 yndM S Protein of unknown function (DUF2512)
LEMALOII_01868 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
LEMALOII_01870 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LEMALOII_01871 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
LEMALOII_01872 9.2e-113 yneB L resolvase
LEMALOII_01873 1.3e-32 ynzC S UPF0291 protein
LEMALOII_01874 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LEMALOII_01875 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
LEMALOII_01876 1.8e-28 yneF S UPF0154 protein
LEMALOII_01877 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
LEMALOII_01878 7.1e-127 ccdA O cytochrome c biogenesis protein
LEMALOII_01879 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
LEMALOII_01880 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
LEMALOII_01881 4.2e-74 yneK S Protein of unknown function (DUF2621)
LEMALOII_01882 4.1e-65 hspX O Spore coat protein
LEMALOII_01883 3.9e-19 sspP S Belongs to the SspP family
LEMALOII_01884 2.2e-14 sspO S Belongs to the SspO family
LEMALOII_01885 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LEMALOII_01886 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LEMALOII_01888 3.1e-08 sspN S Small acid-soluble spore protein N family
LEMALOII_01889 3.9e-35 tlp S Belongs to the Tlp family
LEMALOII_01890 1.2e-73 yneP S Thioesterase-like superfamily
LEMALOII_01891 1.3e-53 yneQ
LEMALOII_01892 4.1e-49 yneR S Belongs to the HesB IscA family
LEMALOII_01893 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LEMALOII_01894 6.6e-69 yccU S CoA-binding protein
LEMALOII_01895 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LEMALOII_01896 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LEMALOII_01897 2.3e-12
LEMALOII_01898 1.3e-57 ynfC
LEMALOII_01899 8.2e-252 agcS E Sodium alanine symporter
LEMALOII_01900 2.4e-297 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
LEMALOII_01902 3.7e-251 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
LEMALOII_01903 4.4e-299 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
LEMALOII_01904 2.4e-80 yngA S membrane
LEMALOII_01905 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
LEMALOII_01906 5.5e-104 yngC S membrane-associated protein
LEMALOII_01907 1.9e-233 nrnB S phosphohydrolase (DHH superfamily)
LEMALOII_01908 6.3e-290 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
LEMALOII_01909 2.2e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
LEMALOII_01910 8e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
LEMALOII_01911 6e-32 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
LEMALOII_01912 3e-251 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
LEMALOII_01913 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LEMALOII_01914 4.4e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
LEMALOII_01915 1.8e-31 S Family of unknown function (DUF5367)
LEMALOII_01917 1.3e-306 yngK T Glycosyl hydrolase-like 10
LEMALOII_01918 2.8e-64 yngL S Protein of unknown function (DUF1360)
LEMALOII_01919 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
LEMALOII_01920 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEMALOII_01921 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEMALOII_01922 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEMALOII_01923 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEMALOII_01924 4.3e-275 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
LEMALOII_01925 6e-193 yoxA 5.1.3.3 G Aldose 1-epimerase
LEMALOII_01926 2.3e-246 yoeA V MATE efflux family protein
LEMALOII_01927 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
LEMALOII_01929 2.2e-96 L Integrase
LEMALOII_01930 3e-34 yoeD G Helix-turn-helix domain
LEMALOII_01931 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
LEMALOII_01932 2.5e-158 gltR1 K Transcriptional regulator
LEMALOII_01933 5e-187 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
LEMALOII_01934 2.7e-293 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
LEMALOII_01935 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
LEMALOII_01936 7.8e-155 gltC K Transcriptional regulator
LEMALOII_01937 4.1e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LEMALOII_01938 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LEMALOII_01939 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
LEMALOII_01940 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
LEMALOII_01941 3e-42 yoxC S Bacterial protein of unknown function (DUF948)
LEMALOII_01942 3.1e-144 yoxB
LEMALOII_01943 7.5e-97 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LEMALOII_01944 6.2e-235 yoaB EGP Major facilitator Superfamily
LEMALOII_01945 1e-284 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
LEMALOII_01946 1.7e-190 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEMALOII_01947 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LEMALOII_01948 1.9e-33 yoaF
LEMALOII_01949 2.2e-08 ywlA S Uncharacterised protein family (UPF0715)
LEMALOII_01950 7e-14
LEMALOII_01951 1.5e-38 S Protein of unknown function (DUF4025)
LEMALOII_01952 1.7e-187 mcpU NT methyl-accepting chemotaxis protein
LEMALOII_01953 8.7e-281 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
LEMALOII_01954 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
LEMALOII_01955 2.3e-111 yoaK S Membrane
LEMALOII_01956 2.5e-197 pelB 4.2.2.10, 4.2.2.2 G Amb_all
LEMALOII_01957 1.1e-132 yoqW S Belongs to the SOS response-associated peptidase family
LEMALOII_01959 3.8e-234 oxdC 4.1.1.2 G Oxalate decarboxylase
LEMALOII_01961 1.9e-146 yoaP 3.1.3.18 K YoaP-like
LEMALOII_01962 1.2e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
LEMALOII_01963 4.1e-89
LEMALOII_01964 2.4e-172 yoaR V vancomycin resistance protein
LEMALOII_01965 1.6e-74 yoaS S Protein of unknown function (DUF2975)
LEMALOII_01966 4.2e-37 yozG K Transcriptional regulator
LEMALOII_01967 1.1e-149 yoaT S Protein of unknown function (DUF817)
LEMALOII_01968 8.6e-159 yoaU K LysR substrate binding domain
LEMALOII_01969 6e-160 yijE EG EamA-like transporter family
LEMALOII_01970 3.7e-78 yoaW
LEMALOII_01971 1.1e-118 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
LEMALOII_01972 2.3e-170 bla 3.5.2.6 V beta-lactamase
LEMALOII_01976 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
LEMALOII_01977 1.8e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
LEMALOII_01978 1.4e-37 S TM2 domain
LEMALOII_01979 5.7e-58 K Helix-turn-helix
LEMALOII_01981 1.6e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
LEMALOII_01982 6.6e-127 yoqW S Belongs to the SOS response-associated peptidase family
LEMALOII_01983 1.8e-178 yobF
LEMALOII_01988 1.7e-207 S aspartate phosphatase
LEMALOII_01990 1.2e-123 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LEMALOII_01991 1.4e-59 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LEMALOII_01992 2.6e-38 S YolD-like protein
LEMALOII_01993 1.2e-49
LEMALOII_01994 0.0 K Psort location Cytoplasmic, score
LEMALOII_01995 2.7e-157 yobJ
LEMALOII_01996 3e-86 S SMI1-KNR4 cell-wall
LEMALOII_01997 4.3e-303 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
LEMALOII_01998 7.9e-105 yokH G SMI1 / KNR4 family
LEMALOII_01999 9.5e-280 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
LEMALOII_02000 0.0 yobO M Pectate lyase superfamily protein
LEMALOII_02001 9.9e-55 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
LEMALOII_02002 1e-136 yobQ K helix_turn_helix, arabinose operon control protein
LEMALOII_02003 2.5e-143 yobR 2.3.1.1 J FR47-like protein
LEMALOII_02004 3e-99 yobS K Transcriptional regulator
LEMALOII_02005 4.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
LEMALOII_02006 1.5e-88 yobU K Bacterial transcription activator, effector binding domain
LEMALOII_02007 9e-178 yobV K WYL domain
LEMALOII_02008 2.5e-95 yobW
LEMALOII_02009 1e-51 czrA K transcriptional
LEMALOII_02010 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LEMALOII_02011 1.5e-92 yozB S membrane
LEMALOII_02012 2.2e-145
LEMALOII_02013 1.9e-94 yocC
LEMALOII_02014 6.9e-189 yocD 3.4.17.13 V peptidase S66
LEMALOII_02015 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
LEMALOII_02016 3.2e-198 desK 2.7.13.3 T Histidine kinase
LEMALOII_02017 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LEMALOII_02018 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
LEMALOII_02019 0.0 recQ 3.6.4.12 L DNA helicase
LEMALOII_02020 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LEMALOII_02021 3.3e-83 dksA T general stress protein
LEMALOII_02022 6.4e-54 yocL
LEMALOII_02023 6.6e-34
LEMALOII_02024 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
LEMALOII_02025 1.1e-40 yozN
LEMALOII_02026 1.9e-36 yocN
LEMALOII_02027 4.2e-56 yozO S Bacterial PH domain
LEMALOII_02028 2.7e-31 yozC
LEMALOII_02029 4e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
LEMALOII_02030 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
LEMALOII_02031 5.4e-166 sodA 1.15.1.1 P Superoxide dismutase
LEMALOII_02032 3.4e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
LEMALOII_02033 5.1e-168 yocS S -transporter
LEMALOII_02034 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
LEMALOII_02035 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
LEMALOII_02036 0.0 yojO P Von Willebrand factor
LEMALOII_02037 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
LEMALOII_02038 1e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LEMALOII_02039 1.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
LEMALOII_02040 1.8e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
LEMALOII_02041 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LEMALOII_02043 4.2e-245 norM V Multidrug efflux pump
LEMALOII_02044 8.4e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LEMALOII_02045 2.1e-125 yojG S deacetylase
LEMALOII_02046 2.2e-60 yojF S Protein of unknown function (DUF1806)
LEMALOII_02047 1.5e-43
LEMALOII_02048 3.5e-163 rarD S -transporter
LEMALOII_02049 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
LEMALOII_02050 3.4e-09
LEMALOII_02051 8.2e-209 gntP EG COG2610 H gluconate symporter and related permeases
LEMALOII_02052 3.8e-66 yodA S tautomerase
LEMALOII_02053 1.7e-57 yodB K transcriptional
LEMALOII_02054 4.8e-108 yodC C nitroreductase
LEMALOII_02055 3.8e-113 mhqD S Carboxylesterase
LEMALOII_02056 5.8e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
LEMALOII_02057 6.2e-28 S Protein of unknown function (DUF3311)
LEMALOII_02058 4.2e-270 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LEMALOII_02059 1.9e-253 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
LEMALOII_02060 1.7e-128 yodH Q Methyltransferase
LEMALOII_02061 5.2e-24 yodI
LEMALOII_02062 2.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
LEMALOII_02063 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
LEMALOII_02064 5.3e-09
LEMALOII_02065 3.6e-54 yodL S YodL-like
LEMALOII_02066 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
LEMALOII_02067 2.8e-24 yozD S YozD-like protein
LEMALOII_02069 1.4e-124 yodN
LEMALOII_02070 1.4e-36 yozE S Belongs to the UPF0346 family
LEMALOII_02071 2.9e-47 yokU S YokU-like protein, putative antitoxin
LEMALOII_02072 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
LEMALOII_02073 2.5e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
LEMALOII_02074 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
LEMALOII_02075 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
LEMALOII_02076 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LEMALOII_02077 1.6e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LEMALOII_02080 2.9e-145 yiiD K acetyltransferase
LEMALOII_02081 1e-256 cgeD M maturation of the outermost layer of the spore
LEMALOII_02082 3.5e-38 cgeC
LEMALOII_02083 1.2e-65 cgeA
LEMALOII_02084 3.3e-188 cgeB S Spore maturation protein
LEMALOII_02085 3.6e-213 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
LEMALOII_02086 2.5e-63 4.2.1.115 GM Polysaccharide biosynthesis protein
LEMALOII_02088 3.6e-108 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LEMALOII_02089 1.4e-10 K Cro/C1-type HTH DNA-binding domain
LEMALOII_02097 1.9e-168 S Calcineurin-like phosphoesterase
LEMALOII_02098 2.5e-30 sspB S spore protein
LEMALOII_02100 3.7e-159 S Thymidylate synthase
LEMALOII_02101 3.1e-38 S Protein of unknown function (DUF1643)
LEMALOII_02105 8.9e-83 yosT L Bacterial transcription activator, effector binding domain
LEMALOII_02106 2.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
LEMALOII_02107 6.1e-38 O Glutaredoxin
LEMALOII_02108 2.8e-66 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LEMALOII_02109 3.3e-97 L HNH endonuclease
LEMALOII_02110 1e-107 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LEMALOII_02111 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LEMALOII_02112 2.3e-117 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LEMALOII_02113 5.1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
LEMALOII_02130 1.5e-255 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
LEMALOII_02132 1.2e-96 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
LEMALOII_02133 5.9e-88 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
LEMALOII_02138 9.9e-115 DR0488 S protein conserved in bacteria
LEMALOII_02139 0.0 2.7.7.7 L DNA polymerase
LEMALOII_02140 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
LEMALOII_02141 1.3e-223 L DNA primase activity
LEMALOII_02142 3.6e-285 3.6.4.12 J DnaB-like helicase C terminal domain
LEMALOII_02143 1.4e-86
LEMALOII_02144 7.6e-180 L AAA domain
LEMALOII_02145 1.3e-170
LEMALOII_02150 0.0 M Parallel beta-helix repeats
LEMALOII_02151 7.7e-149 S Pfam:DUF867
LEMALOII_02154 1e-130 yoqW S Belongs to the SOS response-associated peptidase family
LEMALOII_02155 2.4e-155 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
LEMALOII_02156 2.3e-77
LEMALOII_02163 1e-44
LEMALOII_02165 1.5e-97 S Protein of unknown function (DUF1273)
LEMALOII_02167 3e-78 yoqH M LysM domain
LEMALOII_02170 8.8e-12 S Protein of unknown function (DUF2815)
LEMALOII_02171 6.2e-137 kilA S Phage regulatory protein Rha (Phage_pRha)
LEMALOII_02182 1.1e-33 K Transcriptional regulator
LEMALOII_02183 2.1e-177
LEMALOII_02184 6e-263 S DNA-sulfur modification-associated
LEMALOII_02185 6.8e-198 L Belongs to the 'phage' integrase family
LEMALOII_02190 6.6e-106
LEMALOII_02192 1.2e-86
LEMALOII_02193 1.1e-96 S Super-infection exclusion protein B
LEMALOII_02198 1.1e-07 ywlA S Uncharacterised protein family (UPF0715)
LEMALOII_02199 3.8e-259
LEMALOII_02200 4.6e-35 K Cro/C1-type HTH DNA-binding domain
LEMALOII_02201 1.4e-256
LEMALOII_02203 5.9e-238
LEMALOII_02205 4e-17
LEMALOII_02206 5.7e-55 bldD K domain, Protein
LEMALOII_02209 0.0
LEMALOII_02210 1.8e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LEMALOII_02212 2.6e-230
LEMALOII_02215 1.8e-175
LEMALOII_02216 0.0 gp17a S Terminase-like family
LEMALOII_02217 6.3e-282
LEMALOII_02218 2.1e-266
LEMALOII_02219 1.6e-94
LEMALOII_02220 5.7e-186
LEMALOII_02221 5.1e-81
LEMALOII_02222 1.1e-68
LEMALOII_02224 1.4e-121
LEMALOII_02225 2.6e-91
LEMALOII_02226 8.1e-131
LEMALOII_02227 1.6e-90
LEMALOII_02230 1e-57
LEMALOII_02231 1.1e-172
LEMALOII_02232 8.1e-07
LEMALOII_02233 2.5e-10 xkdX
LEMALOII_02234 2.5e-86
LEMALOII_02235 6.3e-70
LEMALOII_02236 2.8e-193 xerH A Belongs to the 'phage' integrase family
LEMALOII_02241 9.3e-116
LEMALOII_02242 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LEMALOII_02243 6.2e-145 S Phage tail protein
LEMALOII_02244 0.0 S Pfam Transposase IS66
LEMALOII_02245 6.4e-115
LEMALOII_02246 0.0 G Exopolysaccharide biosynthesis protein
LEMALOII_02247 6.5e-164
LEMALOII_02249 1.6e-186 3.5.1.28 M Ami_2
LEMALOII_02250 4.4e-32 bhlA S BhlA holin family
LEMALOII_02251 5.5e-40 S SPP1 phage holin
LEMALOII_02252 3.4e-74 O protein disulfide oxidoreductase activity
LEMALOII_02253 4.1e-242 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LEMALOII_02254 1.2e-70 CO cell redox homeostasis
LEMALOII_02255 0.0 V Peptidase C39 family
LEMALOII_02258 1.9e-239 S impB/mucB/samB family C-terminal domain
LEMALOII_02259 5.8e-55 S YolD-like protein
LEMALOII_02260 1.3e-37
LEMALOII_02262 6.8e-09 S Domain of unknown function (DUF4879)
LEMALOII_02264 2.8e-99 J Acetyltransferase (GNAT) domain
LEMALOII_02265 3.2e-109 yokK S SMI1 / KNR4 family
LEMALOII_02266 1.9e-94 yokJ S SMI1 / KNR4 family (SUKH-1)
LEMALOII_02267 1.2e-302 UW nuclease activity
LEMALOII_02268 6.7e-92 yokH G SMI1 / KNR4 family
LEMALOII_02269 4.1e-203
LEMALOII_02270 3.3e-113 yokF 3.1.31.1 L RNA catabolic process
LEMALOII_02271 1.1e-83 S Bacterial PH domain
LEMALOII_02272 8.4e-156 aacC 2.3.1.81 V aminoglycoside
LEMALOII_02275 8.9e-95
LEMALOII_02276 1.6e-107
LEMALOII_02277 2.7e-307 yokA L Recombinase
LEMALOII_02278 1.4e-96 4.2.1.115 GM Polysaccharide biosynthesis protein
LEMALOII_02279 1.4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
LEMALOII_02280 7e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LEMALOII_02281 1.6e-70 ypoP K transcriptional
LEMALOII_02282 2.6e-223 mepA V MATE efflux family protein
LEMALOII_02283 5.5e-29 ypmT S Uncharacterized ympT
LEMALOII_02284 5e-99 ypmS S protein conserved in bacteria
LEMALOII_02285 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
LEMALOII_02286 3.2e-109 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
LEMALOII_02287 3.1e-40 ypmP S Protein of unknown function (DUF2535)
LEMALOII_02288 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LEMALOII_02289 1.6e-185 pspF K Transcriptional regulator
LEMALOII_02290 4.2e-110 hlyIII S protein, Hemolysin III
LEMALOII_02291 7.4e-112 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
LEMALOII_02292 7.9e-96 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LEMALOII_02293 4.3e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LEMALOII_02294 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
LEMALOII_02295 7.8e-114 ypjP S YpjP-like protein
LEMALOII_02296 1.3e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
LEMALOII_02297 1.7e-75 yphP S Belongs to the UPF0403 family
LEMALOII_02298 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
LEMALOII_02299 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
LEMALOII_02300 3.1e-110 ypgQ S phosphohydrolase
LEMALOII_02301 2.3e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
LEMALOII_02302 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LEMALOII_02303 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
LEMALOII_02304 7.9e-31 cspD K Cold-shock protein
LEMALOII_02305 3.8e-16 degR
LEMALOII_02306 8.1e-31 S Protein of unknown function (DUF2564)
LEMALOII_02307 2.6e-27 ypeQ S Zinc-finger
LEMALOII_02308 8.9e-127 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
LEMALOII_02309 1.1e-121 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LEMALOII_02310 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
LEMALOII_02312 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
LEMALOII_02313 2e-07
LEMALOII_02314 1e-38 ypbS S Protein of unknown function (DUF2533)
LEMALOII_02315 0.0 ypbR S Dynamin family
LEMALOII_02316 5.1e-87 ypbQ S protein conserved in bacteria
LEMALOII_02317 4.4e-208 bcsA Q Naringenin-chalcone synthase
LEMALOII_02318 1.6e-228 pbuX F xanthine
LEMALOII_02319 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LEMALOII_02320 4.2e-294 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LEMALOII_02321 5e-171 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
LEMALOII_02322 7e-104 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
LEMALOII_02323 2.9e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
LEMALOII_02324 3.9e-187 ptxS K transcriptional
LEMALOII_02325 1.7e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
LEMALOII_02326 7.1e-133 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEMALOII_02327 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
LEMALOII_02329 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
LEMALOII_02330 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LEMALOII_02331 3.3e-92 ypsA S Belongs to the UPF0398 family
LEMALOII_02332 1.3e-237 yprB L RNase_H superfamily
LEMALOII_02333 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
LEMALOII_02334 1.9e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
LEMALOII_02335 8.6e-72 hspX O Belongs to the small heat shock protein (HSP20) family
LEMALOII_02336 1.2e-48 yppG S YppG-like protein
LEMALOII_02338 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
LEMALOII_02341 2.6e-188 yppC S Protein of unknown function (DUF2515)
LEMALOII_02342 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LEMALOII_02343 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
LEMALOII_02344 4.7e-93 ypoC
LEMALOII_02345 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LEMALOII_02346 5.7e-129 dnaD L DNA replication protein DnaD
LEMALOII_02347 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
LEMALOII_02348 1.5e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
LEMALOII_02349 3.4e-80 ypmB S protein conserved in bacteria
LEMALOII_02350 6.7e-23 ypmA S Protein of unknown function (DUF4264)
LEMALOII_02351 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
LEMALOII_02352 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LEMALOII_02353 1.2e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LEMALOII_02354 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
LEMALOII_02355 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LEMALOII_02356 4.4e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LEMALOII_02357 3.7e-210 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
LEMALOII_02358 6.9e-130 bshB1 S proteins, LmbE homologs
LEMALOII_02359 6.5e-72 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
LEMALOII_02360 6.3e-148 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LEMALOII_02361 3.1e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
LEMALOII_02362 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
LEMALOII_02363 6.1e-143 ypjB S sporulation protein
LEMALOII_02364 4.4e-98 ypjA S membrane
LEMALOII_02365 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
LEMALOII_02366 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
LEMALOII_02367 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
LEMALOII_02368 8.5e-78 ypiF S Protein of unknown function (DUF2487)
LEMALOII_02369 2.8e-99 ypiB S Belongs to the UPF0302 family
LEMALOII_02370 4.1e-234 S COG0457 FOG TPR repeat
LEMALOII_02371 8.9e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
LEMALOII_02372 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
LEMALOII_02373 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LEMALOII_02374 5.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
LEMALOII_02375 4e-231 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
LEMALOII_02376 6.5e-119 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
LEMALOII_02377 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
LEMALOII_02378 1.2e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LEMALOII_02379 6.6e-295 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LEMALOII_02380 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
LEMALOII_02381 8.1e-207 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LEMALOII_02382 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LEMALOII_02383 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
LEMALOII_02384 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
LEMALOII_02385 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LEMALOII_02386 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
LEMALOII_02387 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
LEMALOII_02388 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
LEMALOII_02389 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
LEMALOII_02390 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LEMALOII_02391 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LEMALOII_02392 5.4e-138 yphF
LEMALOII_02393 1.6e-18 yphE S Protein of unknown function (DUF2768)
LEMALOII_02394 2.3e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
LEMALOII_02395 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
LEMALOII_02396 1.6e-28 ypzH
LEMALOII_02397 2.5e-161 seaA S YIEGIA protein
LEMALOII_02398 1.3e-102 yphA
LEMALOII_02399 1e-07 S YpzI-like protein
LEMALOII_02400 4.1e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LEMALOII_02401 4.3e-206 rpsA 1.17.7.4 J Ribosomal protein S1
LEMALOII_02402 1.9e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
LEMALOII_02403 1.8e-23 S Family of unknown function (DUF5359)
LEMALOII_02404 9.2e-113 ypfA M Flagellar protein YcgR
LEMALOII_02405 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
LEMALOII_02406 4.7e-155 sleB 3.5.1.28 M Spore cortex-lytic enzyme
LEMALOII_02407 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
LEMALOII_02408 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
LEMALOII_02409 5.7e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
LEMALOII_02410 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
LEMALOII_02411 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
LEMALOII_02412 2.8e-81 ypbF S Protein of unknown function (DUF2663)
LEMALOII_02413 4.6e-81 ypbE M Lysin motif
LEMALOII_02414 2.2e-100 ypbD S metal-dependent membrane protease
LEMALOII_02415 3.2e-286 recQ 3.6.4.12 L DNA helicase
LEMALOII_02416 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
LEMALOII_02417 4.7e-41 fer C Ferredoxin
LEMALOII_02418 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LEMALOII_02419 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEMALOII_02420 9e-136 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
LEMALOII_02421 6.8e-201 rsiX
LEMALOII_02422 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
LEMALOII_02423 0.0 resE 2.7.13.3 T Histidine kinase
LEMALOII_02424 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEMALOII_02425 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
LEMALOII_02426 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
LEMALOII_02427 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
LEMALOII_02428 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LEMALOII_02429 1.9e-87 spmB S Spore maturation protein
LEMALOII_02430 3.5e-103 spmA S Spore maturation protein
LEMALOII_02431 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
LEMALOII_02432 4e-98 ypuI S Protein of unknown function (DUF3907)
LEMALOII_02433 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LEMALOII_02434 4.5e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LEMALOII_02435 4.5e-94 ypuF S Domain of unknown function (DUF309)
LEMALOII_02436 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LEMALOII_02437 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
LEMALOII_02438 9.8e-230 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LEMALOII_02439 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
LEMALOII_02440 1.3e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LEMALOII_02441 6e-55 ypuD
LEMALOII_02442 5.2e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
LEMALOII_02443 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
LEMALOII_02444 1.5e-17 S SNARE associated Golgi protein
LEMALOII_02447 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LEMALOII_02448 1.3e-149 ypuA S Secreted protein
LEMALOII_02449 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LEMALOII_02450 1.4e-273 spoVAF EG Stage V sporulation protein AF
LEMALOII_02451 1.4e-110 spoVAEA S stage V sporulation protein
LEMALOII_02452 2.2e-57 spoVAEB S stage V sporulation protein
LEMALOII_02453 9e-192 spoVAD I Stage V sporulation protein AD
LEMALOII_02454 2.3e-78 spoVAC S stage V sporulation protein AC
LEMALOII_02455 1e-67 spoVAB S Stage V sporulation protein AB
LEMALOII_02456 7.4e-112 spoVAA S Stage V sporulation protein AA
LEMALOII_02457 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEMALOII_02458 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
LEMALOII_02459 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
LEMALOII_02460 2.8e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
LEMALOII_02461 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LEMALOII_02462 1.2e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
LEMALOII_02463 2.6e-166 xerD L recombinase XerD
LEMALOII_02464 3.7e-37 S Protein of unknown function (DUF4227)
LEMALOII_02465 2.4e-80 fur P Belongs to the Fur family
LEMALOII_02466 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
LEMALOII_02467 2e-32 yqkK
LEMALOII_02468 5.5e-242 mleA 1.1.1.38 C malic enzyme
LEMALOII_02469 3.1e-235 mleN C Na H antiporter
LEMALOII_02470 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
LEMALOII_02471 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
LEMALOII_02472 4.5e-58 ansR K Transcriptional regulator
LEMALOII_02473 3e-223 yqxK 3.6.4.12 L DNA helicase
LEMALOII_02474 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
LEMALOII_02476 4.4e-169 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
LEMALOII_02477 4e-14 yqkE S Protein of unknown function (DUF3886)
LEMALOII_02478 2.4e-175 yqkD S COG1073 Hydrolases of the alpha beta superfamily
LEMALOII_02479 9.4e-39 yqkC S Protein of unknown function (DUF2552)
LEMALOII_02480 2.8e-54 yqkB S Belongs to the HesB IscA family
LEMALOII_02481 4.7e-196 yqkA K GrpB protein
LEMALOII_02482 8e-60 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
LEMALOII_02483 3.6e-87 yqjY K acetyltransferase
LEMALOII_02484 2.2e-49 S YolD-like protein
LEMALOII_02485 3.1e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LEMALOII_02487 5.2e-226 yqjV G Major Facilitator Superfamily
LEMALOII_02489 7.2e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEMALOII_02490 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
LEMALOII_02491 2.4e-264 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
LEMALOII_02492 3.5e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
LEMALOII_02493 3.4e-180 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
LEMALOII_02494 8.6e-148 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LEMALOII_02495 0.0 rocB E arginine degradation protein
LEMALOII_02496 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
LEMALOII_02497 9.6e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LEMALOII_02498 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LEMALOII_02499 1.6e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LEMALOII_02500 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LEMALOII_02501 7.3e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LEMALOII_02502 4.5e-24 yqzJ
LEMALOII_02503 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LEMALOII_02504 3.6e-142 yqjF S Uncharacterized conserved protein (COG2071)
LEMALOII_02505 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
LEMALOII_02506 4.4e-291 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
LEMALOII_02507 2.2e-75 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
LEMALOII_02509 1.4e-98 yqjB S protein conserved in bacteria
LEMALOII_02510 1.1e-175 yqjA S Putative aromatic acid exporter C-terminal domain
LEMALOII_02511 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
LEMALOII_02512 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
LEMALOII_02513 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
LEMALOII_02514 9.3e-77 yqiW S Belongs to the UPF0403 family
LEMALOII_02515 8.8e-167 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LEMALOII_02516 7.9e-208 norA EGP Major facilitator Superfamily
LEMALOII_02517 2.6e-152 bmrR K helix_turn_helix, mercury resistance
LEMALOII_02518 3.5e-233 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LEMALOII_02519 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LEMALOII_02520 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LEMALOII_02521 3.4e-269 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LEMALOII_02522 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
LEMALOII_02523 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
LEMALOII_02524 7.1e-156 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
LEMALOII_02525 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
LEMALOII_02526 4e-34 yqzF S Protein of unknown function (DUF2627)
LEMALOII_02527 7.1e-164 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LEMALOII_02528 5.7e-277 prpD 4.2.1.79 S 2-methylcitrate dehydratase
LEMALOII_02529 8.1e-210 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
LEMALOII_02530 1.8e-212 mmgC I acyl-CoA dehydrogenase
LEMALOII_02531 4.7e-157 hbdA 1.1.1.157 I Dehydrogenase
LEMALOII_02532 1.2e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
LEMALOII_02533 1.8e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LEMALOII_02534 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
LEMALOII_02535 5.9e-27
LEMALOII_02536 1.3e-215 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
LEMALOII_02538 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
LEMALOII_02539 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
LEMALOII_02540 0.0 recN L May be involved in recombinational repair of damaged DNA
LEMALOII_02541 1.7e-78 argR K Regulates arginine biosynthesis genes
LEMALOII_02542 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
LEMALOII_02543 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LEMALOII_02544 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LEMALOII_02545 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LEMALOII_02546 2.2e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LEMALOII_02547 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LEMALOII_02548 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LEMALOII_02549 2.1e-67 yqhY S protein conserved in bacteria
LEMALOII_02550 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
LEMALOII_02551 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LEMALOII_02552 9.9e-91 spoIIIAH S SpoIIIAH-like protein
LEMALOII_02553 6.9e-103 spoIIIAG S stage III sporulation protein AG
LEMALOII_02554 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
LEMALOII_02555 1.3e-197 spoIIIAE S stage III sporulation protein AE
LEMALOII_02556 2.3e-58 spoIIIAD S Stage III sporulation protein AD
LEMALOII_02557 7.6e-29 spoIIIAC S stage III sporulation protein AC
LEMALOII_02558 2.9e-85 spoIIIAB S Stage III sporulation protein
LEMALOII_02559 1.2e-171 spoIIIAA S stage III sporulation protein AA
LEMALOII_02560 7.9e-37 yqhV S Protein of unknown function (DUF2619)
LEMALOII_02561 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LEMALOII_02562 8.9e-174 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
LEMALOII_02563 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
LEMALOII_02564 2.3e-93 yqhR S Conserved membrane protein YqhR
LEMALOII_02565 2.1e-174 yqhQ S Protein of unknown function (DUF1385)
LEMALOII_02566 2.2e-61 yqhP
LEMALOII_02567 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
LEMALOII_02568 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
LEMALOII_02569 5.2e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
LEMALOII_02570 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
LEMALOII_02571 2.8e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LEMALOII_02572 3.4e-255 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LEMALOII_02573 9.6e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
LEMALOII_02574 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
LEMALOII_02575 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
LEMALOII_02576 1.2e-24 sinI S Anti-repressor SinI
LEMALOII_02577 1e-54 sinR K transcriptional
LEMALOII_02578 2.3e-142 tasA S Cell division protein FtsN
LEMALOII_02579 6.7e-59 sipW 3.4.21.89 U Signal peptidase
LEMALOII_02580 2.1e-116 yqxM
LEMALOII_02581 7.3e-54 yqzG S Protein of unknown function (DUF3889)
LEMALOII_02582 1.4e-26 yqzE S YqzE-like protein
LEMALOII_02583 3.7e-42 S ComG operon protein 7
LEMALOII_02584 5.5e-49 comGF U Putative Competence protein ComGF
LEMALOII_02585 1.1e-59 comGE
LEMALOII_02586 4.4e-71 gspH NU protein transport across the cell outer membrane
LEMALOII_02587 1.4e-47 comGC U Required for transformation and DNA binding
LEMALOII_02588 1.6e-175 comGB NU COG1459 Type II secretory pathway, component PulF
LEMALOII_02589 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LEMALOII_02591 7.2e-175 corA P Mg2 transporter protein
LEMALOII_02592 5.2e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
LEMALOII_02593 1.7e-151 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LEMALOII_02595 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
LEMALOII_02596 1.8e-37 yqgY S Protein of unknown function (DUF2626)
LEMALOII_02597 1.9e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
LEMALOII_02598 8.9e-23 yqgW S Protein of unknown function (DUF2759)
LEMALOII_02599 6.9e-50 yqgV S Thiamine-binding protein
LEMALOII_02600 2.7e-199 yqgU
LEMALOII_02601 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
LEMALOII_02602 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
LEMALOII_02603 5.2e-181 glcK 2.7.1.2 G Glucokinase
LEMALOII_02604 3.1e-33 yqgQ S Protein conserved in bacteria
LEMALOII_02605 1.4e-268 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
LEMALOII_02606 2.5e-09 yqgO
LEMALOII_02607 2.7e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LEMALOII_02608 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
LEMALOII_02609 3.2e-203 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
LEMALOII_02611 9.2e-51 yqzD
LEMALOII_02612 1.9e-75 yqzC S YceG-like family
LEMALOII_02613 9.8e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LEMALOII_02614 6.4e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LEMALOII_02615 4.4e-158 pstA P Phosphate transport system permease
LEMALOII_02616 1.3e-160 pstC P probably responsible for the translocation of the substrate across the membrane
LEMALOII_02617 5.3e-151 pstS P Phosphate
LEMALOII_02618 0.0 pbpA 3.4.16.4 M penicillin-binding protein
LEMALOII_02619 2.5e-231 yqgE EGP Major facilitator superfamily
LEMALOII_02620 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
LEMALOII_02621 4e-73 yqgC S protein conserved in bacteria
LEMALOII_02622 8.5e-134 yqgB S Protein of unknown function (DUF1189)
LEMALOII_02623 2.2e-75 yqgA
LEMALOII_02624 5.2e-47 yqfZ M LysM domain
LEMALOII_02625 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LEMALOII_02626 4.3e-62 yqfX S membrane
LEMALOII_02627 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
LEMALOII_02628 1.9e-77 zur P Belongs to the Fur family
LEMALOII_02629 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
LEMALOII_02630 2.1e-36 yqfT S Protein of unknown function (DUF2624)
LEMALOII_02631 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LEMALOII_02632 1.7e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LEMALOII_02633 2.9e-14 yqfQ S YqfQ-like protein
LEMALOII_02634 2.6e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LEMALOII_02635 5.1e-212 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LEMALOII_02636 6.1e-117 trmK 2.1.1.217 S SAM-dependent methyltransferase
LEMALOII_02637 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
LEMALOII_02638 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LEMALOII_02639 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LEMALOII_02640 4.5e-88 yaiI S Belongs to the UPF0178 family
LEMALOII_02641 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
LEMALOII_02642 4.5e-112 ccpN K CBS domain
LEMALOII_02643 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
LEMALOII_02644 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
LEMALOII_02645 4.8e-145 recO L Involved in DNA repair and RecF pathway recombination
LEMALOII_02646 8.4e-19 S YqzL-like protein
LEMALOII_02647 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LEMALOII_02648 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
LEMALOII_02649 1.6e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
LEMALOII_02650 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LEMALOII_02651 0.0 yqfF S membrane-associated HD superfamily hydrolase
LEMALOII_02653 1.1e-175 phoH T Phosphate starvation-inducible protein PhoH
LEMALOII_02654 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
LEMALOII_02655 2.7e-45 yqfC S sporulation protein YqfC
LEMALOII_02656 6e-25 yqfB
LEMALOII_02657 4.3e-122 yqfA S UPF0365 protein
LEMALOII_02658 5.4e-229 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
LEMALOII_02659 2.5e-61 yqeY S Yqey-like protein
LEMALOII_02660 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
LEMALOII_02661 1.6e-158 yqeW P COG1283 Na phosphate symporter
LEMALOII_02662 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
LEMALOII_02663 1.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LEMALOII_02664 5.4e-175 prmA J Methylates ribosomal protein L11
LEMALOII_02665 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LEMALOII_02666 0.0 dnaK O Heat shock 70 kDa protein
LEMALOII_02667 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LEMALOII_02668 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LEMALOII_02669 4.8e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
LEMALOII_02670 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LEMALOII_02671 1e-54 yqxA S Protein of unknown function (DUF3679)
LEMALOII_02672 6.9e-223 spoIIP M stage II sporulation protein P
LEMALOII_02673 1.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LEMALOII_02674 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
LEMALOII_02675 1.1e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
LEMALOII_02676 4.1e-15 S YqzM-like protein
LEMALOII_02677 0.0 comEC S Competence protein ComEC
LEMALOII_02678 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
LEMALOII_02679 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
LEMALOII_02680 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LEMALOII_02681 2.9e-139 yqeM Q Methyltransferase
LEMALOII_02682 6.9e-62 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LEMALOII_02683 7.4e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
LEMALOII_02684 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LEMALOII_02685 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
LEMALOII_02686 2.7e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LEMALOII_02687 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
LEMALOII_02688 5.3e-95 yqeG S hydrolase of the HAD superfamily
LEMALOII_02690 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
LEMALOII_02691 2.1e-137 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LEMALOII_02692 4.7e-106 yqeD S SNARE associated Golgi protein
LEMALOII_02693 1.2e-171 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
LEMALOII_02694 2.3e-133 yqeB
LEMALOII_02695 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
LEMALOII_02696 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEMALOII_02697 1.4e-281 cisA2 L Recombinase
LEMALOII_02698 1.8e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
LEMALOII_02699 6e-183 arsB 1.20.4.1 P Arsenic resistance protein
LEMALOII_02700 2.8e-73 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEMALOII_02701 1.6e-54 arsR K ArsR family transcriptional regulator
LEMALOII_02702 1.1e-152 yqcI S YqcI/YcgG family
LEMALOII_02703 1.6e-96 S Tetratricopeptide repeat
LEMALOII_02706 3.8e-277 A Pre-toxin TG
LEMALOII_02707 1.1e-104 S Suppressor of fused protein (SUFU)
LEMALOII_02709 5e-60
LEMALOII_02711 1.1e-144 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
LEMALOII_02712 2.6e-68 S Bacteriophage holin family
LEMALOII_02713 4.8e-165 xepA
LEMALOII_02714 1.3e-23
LEMALOII_02715 4.1e-56 xkdW S XkdW protein
LEMALOII_02716 2e-221
LEMALOII_02717 9.6e-40
LEMALOII_02718 9.9e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
LEMALOII_02719 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
LEMALOII_02720 9.6e-71 xkdS S Protein of unknown function (DUF2634)
LEMALOII_02721 1.8e-38 xkdR S Protein of unknown function (DUF2577)
LEMALOII_02722 2.4e-181 yqbQ 3.2.1.96 G NLP P60 protein
LEMALOII_02723 9e-114 xkdP S Lysin motif
LEMALOII_02724 0.0 xkdO L Transglycosylase SLT domain
LEMALOII_02725 1.8e-67 S Phage XkdN-like tail assembly chaperone protein, TAC
LEMALOII_02727 3.6e-76 xkdM S Phage tail tube protein
LEMALOII_02728 5.5e-256 xkdK S Phage tail sheath C-terminal domain
LEMALOII_02729 3.2e-26
LEMALOII_02730 1.4e-77
LEMALOII_02731 4.3e-94 S Bacteriophage HK97-gp10, putative tail-component
LEMALOII_02732 6.7e-65 yqbH S Domain of unknown function (DUF3599)
LEMALOII_02733 2.1e-67 S Protein of unknown function (DUF3199)
LEMALOII_02734 3.6e-51 S YqbF, hypothetical protein domain
LEMALOII_02735 1.9e-167 xkdG S Phage capsid family
LEMALOII_02736 5.1e-128 yqbD 2.1.1.72 L Putative phage serine protease XkdF
LEMALOII_02737 2e-115
LEMALOII_02738 5.7e-169 S Phage Mu protein F like protein
LEMALOII_02739 5.9e-296 yqbA S portal protein
LEMALOII_02740 2.4e-253 S phage terminase, large subunit
LEMALOII_02741 6.3e-107 yqaS L DNA packaging
LEMALOII_02743 6.5e-81 L Transposase
LEMALOII_02744 1.6e-166
LEMALOII_02745 2.1e-31 yqaO S Phage-like element PBSX protein XtrA
LEMALOII_02746 7.2e-74 rusA L Endodeoxyribonuclease RusA
LEMALOII_02748 5.9e-168 xkdC L IstB-like ATP binding protein
LEMALOII_02749 1e-122 3.1.3.16 L DnaD domain protein
LEMALOII_02750 2.5e-155 recT L RecT family
LEMALOII_02751 1.5e-180 yqaJ L YqaJ-like viral recombinase domain
LEMALOII_02755 1.2e-103
LEMALOII_02757 6.5e-37 K Helix-turn-helix XRE-family like proteins
LEMALOII_02758 1.1e-56 K sequence-specific DNA binding
LEMALOII_02760 1e-101 adk 2.7.4.3 F adenylate kinase activity
LEMALOII_02761 1.4e-100 yqaB E IrrE N-terminal-like domain
LEMALOII_02762 2.2e-61 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEMALOII_02763 2e-68 psiE S Protein PsiE homolog
LEMALOII_02764 9e-237 yrkQ T Histidine kinase
LEMALOII_02765 1.1e-127 T Transcriptional regulator
LEMALOII_02766 8.2e-224 yrkO P Protein of unknown function (DUF418)
LEMALOII_02767 6e-105 yrkN K Acetyltransferase (GNAT) family
LEMALOII_02768 1.5e-97 ywrO S Flavodoxin-like fold
LEMALOII_02769 2.8e-79 S Protein of unknown function with HXXEE motif
LEMALOII_02770 4.3e-117 yrkJ S membrane transporter protein
LEMALOII_02771 2.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
LEMALOII_02772 2.3e-212 yrkH P Rhodanese Homology Domain
LEMALOII_02773 1.7e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
LEMALOII_02774 5.1e-84 yrkE O DsrE/DsrF/DrsH-like family
LEMALOII_02775 7.8e-39 yrkD S protein conserved in bacteria
LEMALOII_02776 2.6e-108 yrkC G Cupin domain
LEMALOII_02777 4.8e-151 bltR K helix_turn_helix, mercury resistance
LEMALOII_02778 3.5e-211 blt EGP Major facilitator Superfamily
LEMALOII_02779 1.4e-83 bltD 2.3.1.57 K FR47-like protein
LEMALOII_02780 4.5e-236 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
LEMALOII_02781 2.1e-17 S YrzO-like protein
LEMALOII_02782 1.7e-171 yrdR EG EamA-like transporter family
LEMALOII_02783 5.9e-160 yrdQ K Transcriptional regulator
LEMALOII_02784 2e-199 trkA P Oxidoreductase
LEMALOII_02785 3.5e-158 czcD P COG1230 Co Zn Cd efflux system component
LEMALOII_02786 1.3e-66 yodA S tautomerase
LEMALOII_02787 7.7e-163 gltR K LysR substrate binding domain
LEMALOII_02789 1.5e-231 brnQ E Component of the transport system for branched-chain amino acids
LEMALOII_02790 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
LEMALOII_02791 3.3e-138 azlC E AzlC protein
LEMALOII_02792 2.2e-79 bkdR K helix_turn_helix ASNC type
LEMALOII_02793 4.1e-46 yrdF K ribonuclease inhibitor
LEMALOII_02794 4.1e-231 cypA C Cytochrome P450
LEMALOII_02796 3.1e-101 yrdC 3.5.1.19 Q Isochorismatase family
LEMALOII_02797 1.9e-57 S Protein of unknown function (DUF2568)
LEMALOII_02798 1.2e-91 yrdA S DinB family
LEMALOII_02799 7.6e-168 aadK G Streptomycin adenylyltransferase
LEMALOII_02800 1.5e-194 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
LEMALOII_02801 7.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
LEMALOII_02802 3e-125 yrpD S Domain of unknown function, YrpD
LEMALOII_02804 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
LEMALOII_02805 6.3e-96 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
LEMALOII_02806 4.5e-188 yrpG C Aldo/keto reductase family
LEMALOII_02807 9.5e-226 yraO C Citrate transporter
LEMALOII_02808 1.2e-163 yraN K Transcriptional regulator
LEMALOII_02809 2.4e-206 yraM S PrpF protein
LEMALOII_02811 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
LEMALOII_02812 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LEMALOII_02813 3.2e-155 S Alpha beta hydrolase
LEMALOII_02814 1.7e-60 T sh3 domain protein
LEMALOII_02815 2.4e-61 T sh3 domain protein
LEMALOII_02816 1.3e-66 E Glyoxalase-like domain
LEMALOII_02817 5.3e-37 yraG
LEMALOII_02818 6.4e-63 yraF M Spore coat protein
LEMALOII_02819 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LEMALOII_02820 2.6e-26 yraE
LEMALOII_02821 1.1e-49 yraD M Spore coat protein
LEMALOII_02822 4.3e-47 yraB K helix_turn_helix, mercury resistance
LEMALOII_02823 3.2e-29 yphJ 4.1.1.44 S peroxiredoxin activity
LEMALOII_02824 1.9e-200 adhA 1.1.1.1 C alcohol dehydrogenase
LEMALOII_02825 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
LEMALOII_02826 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
LEMALOII_02827 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
LEMALOII_02828 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
LEMALOII_02829 8.2e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
LEMALOII_02830 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
LEMALOII_02831 0.0 levR K PTS system fructose IIA component
LEMALOII_02832 1.6e-255 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
LEMALOII_02833 3.6e-106 yrhP E LysE type translocator
LEMALOII_02834 1.1e-150 yrhO K Archaeal transcriptional regulator TrmB
LEMALOII_02835 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
LEMALOII_02836 1.7e-151 rsiV S Protein of unknown function (DUF3298)
LEMALOII_02837 0.0 yrhL I Acyltransferase family
LEMALOII_02838 1.5e-46 yrhK S YrhK-like protein
LEMALOII_02839 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
LEMALOII_02840 4.8e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
LEMALOII_02841 4.5e-97 yrhH Q methyltransferase
LEMALOII_02844 1.8e-142 focA P Formate nitrite
LEMALOII_02845 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
LEMALOII_02846 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
LEMALOII_02847 1.4e-78 yrhD S Protein of unknown function (DUF1641)
LEMALOII_02848 4.6e-35 yrhC S YrhC-like protein
LEMALOII_02849 2.6e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
LEMALOII_02850 1.2e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
LEMALOII_02851 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LEMALOII_02852 1.2e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
LEMALOII_02853 3.5e-26 yrzA S Protein of unknown function (DUF2536)
LEMALOII_02854 4.2e-63 yrrS S Protein of unknown function (DUF1510)
LEMALOII_02855 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
LEMALOII_02856 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LEMALOII_02857 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
LEMALOII_02858 2.7e-246 yegQ O COG0826 Collagenase and related proteases
LEMALOII_02859 7.8e-174 yegQ O Peptidase U32
LEMALOII_02860 5.9e-120 yrrM 2.1.1.104 S O-methyltransferase
LEMALOII_02861 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LEMALOII_02862 1.2e-45 yrzB S Belongs to the UPF0473 family
LEMALOII_02863 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LEMALOII_02864 1.7e-41 yrzL S Belongs to the UPF0297 family
LEMALOII_02865 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LEMALOII_02866 2.7e-170 yrrI S AI-2E family transporter
LEMALOII_02867 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
LEMALOII_02868 5.1e-145 glnH ET Belongs to the bacterial solute-binding protein 3 family
LEMALOII_02869 3.6e-109 gluC P ABC transporter
LEMALOII_02870 7.6e-107 glnP P ABC transporter
LEMALOII_02871 8e-08 S Protein of unknown function (DUF3918)
LEMALOII_02872 9.8e-31 yrzR
LEMALOII_02873 1.8e-83 yrrD S protein conserved in bacteria
LEMALOII_02874 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LEMALOII_02875 1.4e-15 S COG0457 FOG TPR repeat
LEMALOII_02876 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LEMALOII_02877 4.7e-213 iscS 2.8.1.7 E Cysteine desulfurase
LEMALOII_02878 1.2e-70 cymR K Transcriptional regulator
LEMALOII_02879 2e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
LEMALOII_02880 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
LEMALOII_02881 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LEMALOII_02882 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
LEMALOII_02884 3.9e-263 lytH 3.5.1.28 M COG3103 SH3 domain protein
LEMALOII_02885 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LEMALOII_02886 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LEMALOII_02887 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LEMALOII_02888 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
LEMALOII_02889 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
LEMALOII_02890 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
LEMALOII_02891 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LEMALOII_02892 9.4e-49 yrzD S Post-transcriptional regulator
LEMALOII_02893 5.7e-270 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LEMALOII_02894 2.2e-114 yrbG S membrane
LEMALOII_02895 1.2e-74 yrzE S Protein of unknown function (DUF3792)
LEMALOII_02896 1.1e-38 yajC U Preprotein translocase subunit YajC
LEMALOII_02897 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LEMALOII_02898 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LEMALOII_02899 2.6e-18 yrzS S Protein of unknown function (DUF2905)
LEMALOII_02900 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LEMALOII_02901 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LEMALOII_02902 4.8e-93 bofC S BofC C-terminal domain
LEMALOII_02903 5.3e-253 csbX EGP Major facilitator Superfamily
LEMALOII_02904 1.3e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
LEMALOII_02905 6.5e-119 yrzF T serine threonine protein kinase
LEMALOII_02907 2.6e-35 S Family of unknown function (DUF5412)
LEMALOII_02908 1.8e-262 alsT E Sodium alanine symporter
LEMALOII_02909 1.9e-127 yebC K transcriptional regulatory protein
LEMALOII_02910 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LEMALOII_02911 9.8e-158 safA M spore coat assembly protein SafA
LEMALOII_02912 2.8e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LEMALOII_02913 5.4e-161 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
LEMALOII_02914 2.7e-307 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
LEMALOII_02915 1.2e-230 nifS 2.8.1.7 E Cysteine desulfurase
LEMALOII_02916 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
LEMALOII_02917 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
LEMALOII_02918 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
LEMALOII_02919 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LEMALOII_02920 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
LEMALOII_02921 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
LEMALOII_02922 4.1e-56 ysxB J ribosomal protein
LEMALOII_02923 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
LEMALOII_02924 9.2e-161 spoIVFB S Stage IV sporulation protein
LEMALOII_02925 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
LEMALOII_02926 2.5e-144 minD D Belongs to the ParA family
LEMALOII_02927 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
LEMALOII_02928 1.4e-84 mreD M shape-determining protein
LEMALOII_02929 2.8e-157 mreC M Involved in formation and maintenance of cell shape
LEMALOII_02930 1.8e-184 mreB D Rod shape-determining protein MreB
LEMALOII_02931 5.9e-126 radC E Belongs to the UPF0758 family
LEMALOII_02932 2.8e-102 maf D septum formation protein Maf
LEMALOII_02933 1.1e-168 spoIIB S Sporulation related domain
LEMALOII_02934 6.6e-85 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
LEMALOII_02935 4.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
LEMALOII_02936 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LEMALOII_02937 1.6e-25
LEMALOII_02938 1.6e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LEMALOII_02939 1.9e-226 spoVID M stage VI sporulation protein D
LEMALOII_02940 4.6e-249 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
LEMALOII_02941 5.6e-183 hemB 4.2.1.24 H Belongs to the ALAD family
LEMALOII_02942 4.4e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
LEMALOII_02943 3e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
LEMALOII_02944 3.6e-146 hemX O cytochrome C
LEMALOII_02945 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LEMALOII_02946 1.4e-89 ysxD
LEMALOII_02947 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
LEMALOII_02948 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LEMALOII_02949 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
LEMALOII_02950 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LEMALOII_02951 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LEMALOII_02952 2.3e-187 ysoA H Tetratricopeptide repeat
LEMALOII_02953 8.1e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LEMALOII_02954 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LEMALOII_02955 3.3e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
LEMALOII_02956 4e-292 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LEMALOII_02957 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LEMALOII_02958 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
LEMALOII_02959 0.0 ilvB 2.2.1.6 E Acetolactate synthase
LEMALOII_02961 7.6e-82 ysnE K acetyltransferase
LEMALOII_02962 9.1e-134 ysnF S protein conserved in bacteria
LEMALOII_02964 1.4e-92 ysnB S Phosphoesterase
LEMALOII_02965 4.5e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LEMALOII_02966 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LEMALOII_02967 2.9e-196 gerM S COG5401 Spore germination protein
LEMALOII_02968 2.1e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
LEMALOII_02969 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
LEMALOII_02970 3.3e-30 gerE K Transcriptional regulator
LEMALOII_02971 7.7e-79 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
LEMALOII_02972 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
LEMALOII_02973 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
LEMALOII_02974 2.4e-107 sdhC C succinate dehydrogenase
LEMALOII_02975 1.2e-79 yslB S Protein of unknown function (DUF2507)
LEMALOII_02976 1.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
LEMALOII_02977 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LEMALOII_02978 2e-52 trxA O Belongs to the thioredoxin family
LEMALOII_02979 4e-305 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
LEMALOII_02981 4.2e-178 etfA C Electron transfer flavoprotein
LEMALOII_02982 1.2e-135 etfB C Electron transfer flavoprotein
LEMALOII_02983 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
LEMALOII_02984 2.7e-100 fadR K Transcriptional regulator
LEMALOII_02985 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LEMALOII_02986 7.3e-68 yshE S membrane
LEMALOII_02987 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LEMALOII_02988 0.0 polX L COG1796 DNA polymerase IV (family X)
LEMALOII_02989 1.3e-85 cvpA S membrane protein, required for colicin V production
LEMALOII_02990 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LEMALOII_02991 4e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LEMALOII_02992 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LEMALOII_02993 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LEMALOII_02994 3.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LEMALOII_02995 2.6e-32 sspI S Belongs to the SspI family
LEMALOII_02996 4.4e-208 ysfB KT regulator
LEMALOII_02997 7.2e-264 glcD 1.1.3.15 C Glycolate oxidase subunit
LEMALOII_02998 5.6e-258 glcF C Glycolate oxidase
LEMALOII_02999 3.6e-38 ysfE 4.4.1.5 E lactoylglutathione lyase activity
LEMALOII_03001 0.0 cstA T Carbon starvation protein
LEMALOII_03002 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
LEMALOII_03003 3.4e-144 araQ G transport system permease
LEMALOII_03004 1.4e-167 araP G carbohydrate transport
LEMALOII_03005 2.8e-254 araN G carbohydrate transport
LEMALOII_03006 5e-226 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
LEMALOII_03007 4.1e-147 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
LEMALOII_03008 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
LEMALOII_03009 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
LEMALOII_03010 1.9e-294 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
LEMALOII_03011 2.1e-190 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
LEMALOII_03012 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
LEMALOII_03013 9.2e-68 ysdB S Sigma-w pathway protein YsdB
LEMALOII_03014 7.5e-45 ysdA S Membrane
LEMALOII_03015 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LEMALOII_03016 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
LEMALOII_03017 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LEMALOII_03019 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
LEMALOII_03020 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
LEMALOII_03021 6.3e-131 lytT T COG3279 Response regulator of the LytR AlgR family
LEMALOII_03022 0.0 lytS 2.7.13.3 T Histidine kinase
LEMALOII_03023 1.5e-149 ysaA S HAD-hyrolase-like
LEMALOII_03024 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LEMALOII_03025 3.8e-159 ytxC S YtxC-like family
LEMALOII_03026 4.9e-111 ytxB S SNARE associated Golgi protein
LEMALOII_03027 3e-173 dnaI L Primosomal protein DnaI
LEMALOII_03028 3.5e-266 dnaB L Membrane attachment protein
LEMALOII_03029 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LEMALOII_03030 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LEMALOII_03031 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LEMALOII_03032 9.9e-67 ytcD K Transcriptional regulator
LEMALOII_03033 4.9e-205 ytbD EGP Major facilitator Superfamily
LEMALOII_03034 8.9e-161 ytbE S reductase
LEMALOII_03035 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LEMALOII_03036 1.1e-107 ytaF P Probably functions as a manganese efflux pump
LEMALOII_03037 2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LEMALOII_03038 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LEMALOII_03039 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
LEMALOII_03040 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEMALOII_03041 1.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
LEMALOII_03042 1.8e-242 icd 1.1.1.42 C isocitrate
LEMALOII_03043 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
LEMALOII_03044 4.7e-71 yeaL S membrane
LEMALOII_03045 2.6e-192 ytvI S sporulation integral membrane protein YtvI
LEMALOII_03046 1.8e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
LEMALOII_03047 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
LEMALOII_03048 3.4e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LEMALOII_03049 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
LEMALOII_03050 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LEMALOII_03051 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
LEMALOII_03052 0.0 dnaE 2.7.7.7 L DNA polymerase
LEMALOII_03053 3.2e-56 ytrH S Sporulation protein YtrH
LEMALOII_03054 8.2e-69 ytrI
LEMALOII_03055 9.2e-29
LEMALOII_03056 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
LEMALOII_03057 2.4e-47 ytpI S YtpI-like protein
LEMALOII_03058 8e-241 ytoI K transcriptional regulator containing CBS domains
LEMALOII_03059 1.2e-158 ytnM S membrane transporter protein
LEMALOII_03060 4.9e-240 ytnL 3.5.1.47 E hydrolase activity
LEMALOII_03061 6.3e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
LEMALOII_03062 1e-256 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LEMALOII_03063 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
LEMALOII_03064 1.2e-185 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LEMALOII_03065 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
LEMALOII_03066 7.6e-121 tcyM U Binding-protein-dependent transport system inner membrane component
LEMALOII_03067 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
LEMALOII_03068 1.5e-149 tcyK M Bacterial periplasmic substrate-binding proteins
LEMALOII_03069 9.5e-152 tcyK ET Bacterial periplasmic substrate-binding proteins
LEMALOII_03070 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
LEMALOII_03071 2.9e-173 ytlI K LysR substrate binding domain
LEMALOII_03072 1.7e-130 ytkL S Belongs to the UPF0173 family
LEMALOII_03073 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEMALOII_03075 3.1e-267 argH 4.3.2.1 E argininosuccinate lyase
LEMALOII_03076 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
LEMALOII_03077 3.6e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
LEMALOII_03078 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LEMALOII_03079 7e-165 ytxK 2.1.1.72 L DNA methylase
LEMALOII_03080 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LEMALOII_03081 8.7e-70 ytfJ S Sporulation protein YtfJ
LEMALOII_03082 5.6e-116 ytfI S Protein of unknown function (DUF2953)
LEMALOII_03083 1.3e-87 yteJ S RDD family
LEMALOII_03084 2.4e-181 sppA OU signal peptide peptidase SppA
LEMALOII_03085 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LEMALOII_03086 0.0 ytcJ S amidohydrolase
LEMALOII_03087 2e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LEMALOII_03088 2e-29 sspB S spore protein
LEMALOII_03089 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LEMALOII_03090 2.2e-210 iscS2 2.8.1.7 E Cysteine desulfurase
LEMALOII_03091 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
LEMALOII_03092 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LEMALOII_03093 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
LEMALOII_03094 3.4e-109 yttP K Transcriptional regulator
LEMALOII_03095 1.2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
LEMALOII_03096 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
LEMALOII_03097 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LEMALOII_03099 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LEMALOII_03100 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LEMALOII_03101 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
LEMALOII_03102 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
LEMALOII_03103 1.9e-225 acuC BQ histone deacetylase
LEMALOII_03104 1.4e-125 motS N Flagellar motor protein
LEMALOII_03105 7.1e-147 motA N flagellar motor
LEMALOII_03106 1.7e-182 ccpA K catabolite control protein A
LEMALOII_03107 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
LEMALOII_03108 4.4e-55 ytxJ O Protein of unknown function (DUF2847)
LEMALOII_03109 6.6e-17 ytxH S COG4980 Gas vesicle protein
LEMALOII_03110 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LEMALOII_03111 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
LEMALOII_03112 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
LEMALOII_03113 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LEMALOII_03114 9.8e-149 ytpQ S Belongs to the UPF0354 family
LEMALOII_03115 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
LEMALOII_03116 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
LEMALOII_03117 4.7e-207 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
LEMALOII_03118 9.8e-52 ytzB S small secreted protein
LEMALOII_03119 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
LEMALOII_03120 6.4e-151 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
LEMALOII_03121 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LEMALOII_03122 2e-45 ytzH S YtzH-like protein
LEMALOII_03123 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
LEMALOII_03124 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
LEMALOII_03125 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
LEMALOII_03126 1.3e-165 ytlQ
LEMALOII_03127 4.3e-103 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LEMALOII_03128 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
LEMALOII_03129 7.1e-272 pepV 3.5.1.18 E Dipeptidase
LEMALOII_03130 7.2e-226 pbuO S permease
LEMALOII_03131 3.9e-207 ythQ U Bacterial ABC transporter protein EcsB
LEMALOII_03132 4.3e-132 ythP V ABC transporter
LEMALOII_03133 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
LEMALOII_03134 2.6e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LEMALOII_03135 1.9e-281 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LEMALOII_03136 8.2e-232 ytfP S HI0933-like protein
LEMALOII_03137 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
LEMALOII_03138 3.1e-26 yteV S Sporulation protein Cse60
LEMALOII_03139 4.8e-117 yteU S Integral membrane protein
LEMALOII_03140 9.2e-258 yteT S Oxidoreductase family, C-terminal alpha/beta domain
LEMALOII_03141 4.6e-73 yteS G transport
LEMALOII_03142 4.7e-226 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
LEMALOII_03143 2e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
LEMALOII_03144 0.0 ytdP K Transcriptional regulator
LEMALOII_03145 1.2e-290 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
LEMALOII_03146 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
LEMALOII_03147 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
LEMALOII_03148 1.9e-225 bioI 1.14.14.46 C Cytochrome P450
LEMALOII_03149 2.2e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LEMALOII_03150 3.7e-128 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LEMALOII_03151 1.4e-220 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
LEMALOII_03152 2.4e-261 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
LEMALOII_03153 1.6e-142 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
LEMALOII_03154 1.3e-173 ytaP S Acetyl xylan esterase (AXE1)
LEMALOII_03155 2.3e-190 msmR K Transcriptional regulator
LEMALOII_03156 2.3e-248 msmE G Bacterial extracellular solute-binding protein
LEMALOII_03157 3.7e-168 amyD P ABC transporter
LEMALOII_03158 1.5e-144 amyC P ABC transporter (permease)
LEMALOII_03159 4e-253 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
LEMALOII_03160 2.1e-51 ytwF P Sulfurtransferase
LEMALOII_03161 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
LEMALOII_03162 7.7e-55 ytvB S Protein of unknown function (DUF4257)
LEMALOII_03163 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
LEMALOII_03164 2.1e-211 yttB EGP Major facilitator Superfamily
LEMALOII_03165 1.8e-43 yttA 2.7.13.3 S Pfam Transposase IS66
LEMALOII_03166 0.0 bceB V ABC transporter (permease)
LEMALOII_03167 1.1e-138 bceA V ABC transporter, ATP-binding protein
LEMALOII_03168 5.6e-186 T PhoQ Sensor
LEMALOII_03169 5.2e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEMALOII_03170 8.5e-235 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
LEMALOII_03171 3.1e-127 ytrE V ABC transporter, ATP-binding protein
LEMALOII_03172 5.9e-148
LEMALOII_03173 6.1e-169 P ABC-2 family transporter protein
LEMALOII_03174 1.1e-161 ytrB P abc transporter atp-binding protein
LEMALOII_03175 5.1e-66 ytrA K GntR family transcriptional regulator
LEMALOII_03177 6.7e-41 ytzC S Protein of unknown function (DUF2524)
LEMALOII_03178 2.1e-190 yhcC S Fe-S oxidoreductase
LEMALOII_03179 3.3e-106 ytqB J Putative rRNA methylase
LEMALOII_03180 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
LEMALOII_03181 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
LEMALOII_03182 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LEMALOII_03183 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
LEMALOII_03184 0.0 asnB 6.3.5.4 E Asparagine synthase
LEMALOII_03185 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LEMALOII_03186 2.2e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LEMALOII_03187 1.2e-38 ytmB S Protein of unknown function (DUF2584)
LEMALOII_03188 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
LEMALOII_03189 5e-190 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
LEMALOII_03190 1.4e-144 ytlC P ABC transporter
LEMALOII_03191 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
LEMALOII_03192 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
LEMALOII_03193 5.4e-63 ytkC S Bacteriophage holin family
LEMALOII_03194 2.1e-76 dps P Belongs to the Dps family
LEMALOII_03196 3.6e-73 ytkA S YtkA-like
LEMALOII_03197 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LEMALOII_03198 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
LEMALOII_03199 3.6e-41 rpmE2 J Ribosomal protein L31
LEMALOII_03200 4.7e-249 cydA 1.10.3.14 C oxidase, subunit
LEMALOII_03201 7.3e-189 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
LEMALOII_03202 1.1e-24 S Domain of Unknown Function (DUF1540)
LEMALOII_03203 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
LEMALOII_03204 3.2e-234 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
LEMALOII_03205 1.2e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
LEMALOII_03206 1.8e-170 troA P Belongs to the bacterial solute-binding protein 9 family
LEMALOII_03207 1.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
LEMALOII_03208 2.4e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
LEMALOII_03209 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LEMALOII_03210 3.8e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
LEMALOII_03211 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LEMALOII_03212 8.5e-273 menF 5.4.4.2 HQ Isochorismate synthase
LEMALOII_03213 2.6e-132 dksA T COG1734 DnaK suppressor protein
LEMALOII_03214 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
LEMALOII_03215 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LEMALOII_03216 3.9e-181 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
LEMALOII_03217 3.6e-235 ytcC M Glycosyltransferase Family 4
LEMALOII_03219 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
LEMALOII_03220 1.8e-217 cotSA M Glycosyl transferases group 1
LEMALOII_03221 1.8e-206 cotI S Spore coat protein
LEMALOII_03222 9.9e-77 tspO T membrane
LEMALOII_03223 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
LEMALOII_03224 4.3e-288 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
LEMALOII_03225 1.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
LEMALOII_03226 3.6e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LEMALOII_03227 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LEMALOII_03236 7.8e-08
LEMALOII_03237 1.3e-09
LEMALOII_03244 2e-08
LEMALOII_03249 3.4e-39 S COG NOG14552 non supervised orthologous group
LEMALOII_03250 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
LEMALOII_03251 3.4e-94 M1-753 M FR47-like protein
LEMALOII_03252 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
LEMALOII_03253 1.4e-77 yuaF OU Membrane protein implicated in regulation of membrane protease activity
LEMALOII_03254 3.9e-84 yuaE S DinB superfamily
LEMALOII_03255 7.9e-108 yuaD
LEMALOII_03256 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
LEMALOII_03257 8e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
LEMALOII_03258 1.1e-95 yuaC K Belongs to the GbsR family
LEMALOII_03259 2.2e-91 yuaB
LEMALOII_03260 5e-122 ktrA P COG0569 K transport systems, NAD-binding component
LEMALOII_03261 5.4e-237 ktrB P Potassium
LEMALOII_03262 1e-38 yiaA S yiaA/B two helix domain
LEMALOII_03263 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LEMALOII_03264 6.2e-277 yubD P Major Facilitator Superfamily
LEMALOII_03265 2.6e-88 cdoA 1.13.11.20 S Cysteine dioxygenase type I
LEMALOII_03267 1.2e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
LEMALOII_03268 6.3e-197 yubA S transporter activity
LEMALOII_03269 3.3e-183 ygjR S Oxidoreductase
LEMALOII_03270 1.4e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
LEMALOII_03271 2.5e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
LEMALOII_03272 1.3e-281 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
LEMALOII_03273 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
LEMALOII_03274 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
LEMALOII_03275 5.1e-239 mcpA NT chemotaxis protein
LEMALOII_03276 2.2e-295 mcpA NT chemotaxis protein
LEMALOII_03277 1.5e-222 mcpA NT chemotaxis protein
LEMALOII_03278 3.2e-225 mcpA NT chemotaxis protein
LEMALOII_03279 2.6e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
LEMALOII_03280 1e-35
LEMALOII_03281 2.1e-72 yugU S Uncharacterised protein family UPF0047
LEMALOII_03282 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
LEMALOII_03283 2.6e-236 yugS S COG1253 Hemolysins and related proteins containing CBS domains
LEMALOII_03284 1.4e-116 yugP S Zn-dependent protease
LEMALOII_03285 4.6e-39
LEMALOII_03286 1.1e-53 mstX S Membrane-integrating protein Mistic
LEMALOII_03287 1.7e-182 yugO P COG1226 Kef-type K transport systems
LEMALOII_03288 1.3e-72 yugN S YugN-like family
LEMALOII_03290 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
LEMALOII_03291 2.8e-229 yugK C Dehydrogenase
LEMALOII_03292 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
LEMALOII_03293 1.1e-34 yuzA S Domain of unknown function (DUF378)
LEMALOII_03294 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
LEMALOII_03295 4.3e-200 yugH 2.6.1.1 E Aminotransferase
LEMALOII_03296 1.6e-85 alaR K Transcriptional regulator
LEMALOII_03297 1e-156 yugF I Hydrolase
LEMALOII_03298 9.8e-42 yugE S Domain of unknown function (DUF1871)
LEMALOII_03299 1.8e-228 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
LEMALOII_03300 4.6e-233 T PhoQ Sensor
LEMALOII_03301 2e-70 kapB G Kinase associated protein B
LEMALOII_03302 1.9e-115 kapD L the KinA pathway to sporulation
LEMALOII_03304 3.5e-186 yuxJ EGP Major facilitator Superfamily
LEMALOII_03305 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
LEMALOII_03306 6.3e-75 yuxK S protein conserved in bacteria
LEMALOII_03307 6.3e-78 yufK S Family of unknown function (DUF5366)
LEMALOII_03308 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
LEMALOII_03309 2.3e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
LEMALOII_03310 3.4e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
LEMALOII_03311 1.1e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
LEMALOII_03312 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
LEMALOII_03313 4.5e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
LEMALOII_03314 1.3e-233 maeN C COG3493 Na citrate symporter
LEMALOII_03315 1.9e-14
LEMALOII_03316 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
LEMALOII_03317 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LEMALOII_03318 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LEMALOII_03319 3.8e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LEMALOII_03320 4.8e-79 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LEMALOII_03321 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LEMALOII_03322 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
LEMALOII_03323 9.2e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
LEMALOII_03324 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LEMALOII_03325 0.0 comP 2.7.13.3 T Histidine kinase
LEMALOII_03327 2.5e-162 comQ H Polyprenyl synthetase
LEMALOII_03329 1.1e-22 yuzC
LEMALOII_03330 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
LEMALOII_03331 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LEMALOII_03332 2.9e-104 pncA Q COG1335 Amidases related to nicotinamidase
LEMALOII_03333 1.6e-67 yueI S Protein of unknown function (DUF1694)
LEMALOII_03334 7.4e-39 yueH S YueH-like protein
LEMALOII_03335 2.1e-32 yueG S Spore germination protein gerPA/gerPF
LEMALOII_03336 1.9e-190 yueF S transporter activity
LEMALOII_03337 6.1e-72 S Protein of unknown function (DUF2283)
LEMALOII_03338 2.9e-24 S Protein of unknown function (DUF2642)
LEMALOII_03339 4.8e-96 yueE S phosphohydrolase
LEMALOII_03340 4.4e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEMALOII_03341 6.6e-65 yueC S Family of unknown function (DUF5383)
LEMALOII_03342 0.0 esaA S type VII secretion protein EsaA
LEMALOII_03343 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
LEMALOII_03344 2.3e-211 essB S WXG100 protein secretion system (Wss), protein YukC
LEMALOII_03345 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
LEMALOII_03346 2.8e-45 esxA S Belongs to the WXG100 family
LEMALOII_03347 6.5e-229 yukF QT Transcriptional regulator
LEMALOII_03348 1.2e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
LEMALOII_03349 1.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
LEMALOII_03350 3.8e-36 mbtH S MbtH-like protein
LEMALOII_03351 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEMALOII_03352 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
LEMALOII_03353 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
LEMALOII_03354 2.3e-226 entC 5.4.4.2 HQ Isochorismate synthase
LEMALOII_03355 7.3e-141 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LEMALOII_03356 1.3e-167 besA S Putative esterase
LEMALOII_03357 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
LEMALOII_03358 1.1e-93 bioY S Biotin biosynthesis protein
LEMALOII_03359 3.9e-211 yuiF S antiporter
LEMALOII_03360 1.5e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LEMALOII_03361 1.2e-77 yuiD S protein conserved in bacteria
LEMALOII_03362 9.5e-118 yuiC S protein conserved in bacteria
LEMALOII_03363 8.4e-27 yuiB S Putative membrane protein
LEMALOII_03364 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
LEMALOII_03365 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
LEMALOII_03367 4.9e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LEMALOII_03368 9e-118 paiB K Putative FMN-binding domain
LEMALOII_03369 4.7e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LEMALOII_03370 3.7e-63 erpA S Belongs to the HesB IscA family
LEMALOII_03371 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LEMALOII_03372 2.4e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LEMALOII_03373 3.2e-39 yuzB S Belongs to the UPF0349 family
LEMALOII_03374 1.2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
LEMALOII_03375 3.5e-57 yuzD S protein conserved in bacteria
LEMALOII_03376 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
LEMALOII_03377 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
LEMALOII_03378 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LEMALOII_03379 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LEMALOII_03380 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
LEMALOII_03381 2e-199 yutH S Spore coat protein
LEMALOII_03382 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
LEMALOII_03383 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LEMALOII_03384 1e-75 yutE S Protein of unknown function DUF86
LEMALOII_03385 9.7e-48 yutD S protein conserved in bacteria
LEMALOII_03386 4.9e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LEMALOII_03387 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LEMALOII_03388 4.5e-196 lytH M Peptidase, M23
LEMALOII_03389 8.4e-134 yunB S Sporulation protein YunB (Spo_YunB)
LEMALOII_03390 4.8e-48 yunC S Domain of unknown function (DUF1805)
LEMALOII_03391 5.8e-266 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
LEMALOII_03392 2e-141 yunE S membrane transporter protein
LEMALOII_03393 4.3e-171 yunF S Protein of unknown function DUF72
LEMALOII_03394 3e-62 yunG
LEMALOII_03395 1e-259 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
LEMALOII_03396 1.2e-302 pucR QT COG2508 Regulator of polyketide synthase expression
LEMALOII_03397 2.1e-236 pbuX F Permease family
LEMALOII_03398 1.3e-224 pbuX F xanthine
LEMALOII_03399 6.6e-284 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
LEMALOII_03400 7.3e-61 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
LEMALOII_03401 7.9e-99 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
LEMALOII_03402 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
LEMALOII_03403 3.4e-152 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
LEMALOII_03404 3.6e-111 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
LEMALOII_03405 1.7e-190 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LEMALOII_03407 1.9e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
LEMALOII_03408 1.6e-238 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
LEMALOII_03409 2.4e-169 bsn L Ribonuclease
LEMALOII_03410 1.2e-205 msmX P Belongs to the ABC transporter superfamily
LEMALOII_03411 1.1e-135 yurK K UTRA
LEMALOII_03412 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
LEMALOII_03413 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
LEMALOII_03414 1.4e-156 yurN G Binding-protein-dependent transport system inner membrane component
LEMALOII_03415 1.3e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
LEMALOII_03416 1.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
LEMALOII_03417 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
LEMALOII_03418 1.8e-209 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
LEMALOII_03420 1e-41
LEMALOII_03421 7.6e-67 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEMALOII_03422 3.5e-271 sufB O FeS cluster assembly
LEMALOII_03423 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
LEMALOII_03424 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LEMALOII_03425 1.4e-245 sufD O assembly protein SufD
LEMALOII_03426 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
LEMALOII_03427 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LEMALOII_03428 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
LEMALOII_03429 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
LEMALOII_03430 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LEMALOII_03431 2.4e-56 yusD S SCP-2 sterol transfer family
LEMALOII_03432 5.6e-55 traF CO Thioredoxin
LEMALOII_03433 3.3e-74 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
LEMALOII_03434 1.1e-39 yusG S Protein of unknown function (DUF2553)
LEMALOII_03435 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
LEMALOII_03436 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
LEMALOII_03437 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
LEMALOII_03438 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
LEMALOII_03439 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
LEMALOII_03440 4.7e-09 S YuzL-like protein
LEMALOII_03441 2.2e-165 fadM E Proline dehydrogenase
LEMALOII_03442 5.1e-40
LEMALOII_03443 3.2e-53 yusN M Coat F domain
LEMALOII_03444 5.4e-75 yusO K Iron dependent repressor, N-terminal DNA binding domain
LEMALOII_03445 3.8e-293 yusP P Major facilitator superfamily
LEMALOII_03446 8.4e-66 yusQ S Tautomerase enzyme
LEMALOII_03447 2.5e-62 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LEMALOII_03448 2.5e-50 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LEMALOII_03449 2.7e-160 yusT K LysR substrate binding domain
LEMALOII_03450 3.8e-47 yusU S Protein of unknown function (DUF2573)
LEMALOII_03451 1e-153 yusV 3.6.3.34 HP ABC transporter
LEMALOII_03452 5.6e-66 S YusW-like protein
LEMALOII_03453 6.3e-258 pepF2 E COG1164 Oligoendopeptidase F
LEMALOII_03454 3.9e-34 pepF2 E COG1164 Oligoendopeptidase F
LEMALOII_03455 4.7e-154 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LEMALOII_03456 1.2e-79 dps P Ferritin-like domain
LEMALOII_03457 9.6e-237 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LEMALOII_03458 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEMALOII_03459 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
LEMALOII_03460 4.3e-158 yuxN K Transcriptional regulator
LEMALOII_03461 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LEMALOII_03462 2.3e-24 S Protein of unknown function (DUF3970)
LEMALOII_03463 3.7e-247 gerAA EG Spore germination protein
LEMALOII_03464 9.1e-198 gerAB E Spore germination protein
LEMALOII_03465 6e-189 gerAC S Spore germination B3/ GerAC like, C-terminal
LEMALOII_03466 1.3e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LEMALOII_03467 5.5e-187 vraS 2.7.13.3 T Histidine kinase
LEMALOII_03468 5.6e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
LEMALOII_03469 9.3e-129 liaG S Putative adhesin
LEMALOII_03470 2.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
LEMALOII_03471 5.6e-62 liaI S membrane
LEMALOII_03472 4.8e-227 yvqJ EGP Major facilitator Superfamily
LEMALOII_03473 6.5e-102 yvqK 2.5.1.17 S Adenosyltransferase
LEMALOII_03474 2.8e-249 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
LEMALOII_03475 7.7e-186 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEMALOII_03476 1.8e-170 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
LEMALOII_03477 6.2e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LEMALOII_03478 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
LEMALOII_03479 0.0 T PhoQ Sensor
LEMALOII_03480 3.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEMALOII_03481 3.6e-22
LEMALOII_03482 1.8e-96 yvrI K RNA polymerase
LEMALOII_03483 2.4e-19 S YvrJ protein family
LEMALOII_03484 7.3e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
LEMALOII_03485 1.3e-64 yvrL S Regulatory protein YrvL
LEMALOII_03486 1.8e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
LEMALOII_03487 7.1e-124 macB V ABC transporter, ATP-binding protein
LEMALOII_03488 4.8e-176 M Efflux transporter rnd family, mfp subunit
LEMALOII_03489 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
LEMALOII_03490 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEMALOII_03491 9.3e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEMALOII_03492 2.1e-179 fhuD P ABC transporter
LEMALOII_03494 2.6e-237 yvsH E Arginine ornithine antiporter
LEMALOII_03495 6.5e-16 S Small spore protein J (Spore_SspJ)
LEMALOII_03496 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
LEMALOII_03497 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
LEMALOII_03498 8e-171 yvgK P COG1910 Periplasmic molybdate-binding protein domain
LEMALOII_03499 5.8e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
LEMALOII_03500 4.7e-120 modB P COG4149 ABC-type molybdate transport system, permease component
LEMALOII_03501 9.1e-158 yvgN S reductase
LEMALOII_03502 5.4e-86 yvgO
LEMALOII_03503 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
LEMALOII_03504 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
LEMALOII_03505 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LEMALOII_03506 0.0 helD 3.6.4.12 L DNA helicase
LEMALOII_03507 4.1e-107 yvgT S membrane
LEMALOII_03508 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
LEMALOII_03509 1.6e-104 bdbD O Thioredoxin
LEMALOII_03510 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
LEMALOII_03511 0.0 copA 3.6.3.54 P P-type ATPase
LEMALOII_03512 1.5e-29 copZ P Copper resistance protein CopZ
LEMALOII_03513 2.2e-48 csoR S transcriptional
LEMALOII_03514 2.1e-199 yvaA 1.1.1.371 S Oxidoreductase
LEMALOII_03515 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LEMALOII_03516 0.0 yvaC S Fusaric acid resistance protein-like
LEMALOII_03517 5.7e-73 yvaD S Family of unknown function (DUF5360)
LEMALOII_03518 2.8e-55 yvaE P Small Multidrug Resistance protein
LEMALOII_03519 4.1e-101 K Bacterial regulatory proteins, tetR family
LEMALOII_03520 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LEMALOII_03522 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LEMALOII_03523 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LEMALOII_03524 5.6e-143 est 3.1.1.1 S Carboxylesterase
LEMALOII_03525 2.4e-23 secG U Preprotein translocase subunit SecG
LEMALOII_03526 3.7e-153 yvaM S Serine aminopeptidase, S33
LEMALOII_03527 7.5e-36 yvzC K Transcriptional
LEMALOII_03528 4e-69 K transcriptional
LEMALOII_03529 8e-70 yvaO K Cro/C1-type HTH DNA-binding domain
LEMALOII_03530 2.2e-54 yodB K transcriptional
LEMALOII_03531 4.2e-226 NT chemotaxis protein
LEMALOII_03532 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
LEMALOII_03533 1.1e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LEMALOII_03534 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
LEMALOII_03535 3e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
LEMALOII_03536 8.7e-61 yvbF K Belongs to the GbsR family
LEMALOII_03537 7.9e-13 S Sporulation delaying protein SdpA
LEMALOII_03538 7.6e-172
LEMALOII_03539 4.4e-08
LEMALOII_03540 3.3e-96 sdpI S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
LEMALOII_03541 4.5e-45 sdpR K transcriptional
LEMALOII_03542 8.7e-114 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
LEMALOII_03543 2.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LEMALOII_03544 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
LEMALOII_03545 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
LEMALOII_03546 1.4e-98 yvbF K Belongs to the GbsR family
LEMALOII_03547 6.4e-103 yvbG U UPF0056 membrane protein
LEMALOII_03548 8.6e-113 yvbH S YvbH-like oligomerisation region
LEMALOII_03549 4.2e-124 exoY M Membrane
LEMALOII_03550 0.0 tcaA S response to antibiotic
LEMALOII_03551 7.7e-82 yvbK 3.1.3.25 K acetyltransferase
LEMALOII_03552 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LEMALOII_03553 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
LEMALOII_03554 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LEMALOII_03555 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
LEMALOII_03556 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LEMALOII_03557 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LEMALOII_03558 1.6e-252 araE EGP Major facilitator Superfamily
LEMALOII_03559 5.5e-203 araR K transcriptional
LEMALOII_03560 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LEMALOII_03561 3.9e-159 yvbU K Transcriptional regulator
LEMALOII_03562 8.5e-157 yvbV EG EamA-like transporter family
LEMALOII_03563 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
LEMALOII_03564 4.3e-197 yvbX S Glycosyl hydrolase
LEMALOII_03565 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
LEMALOII_03566 1.2e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
LEMALOII_03567 1.5e-137 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
LEMALOII_03568 2.6e-106 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LEMALOII_03569 8.9e-201 desK 2.7.13.3 T Histidine kinase
LEMALOII_03570 6.2e-134 yvfS V COG0842 ABC-type multidrug transport system, permease component
LEMALOII_03571 3e-162 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
LEMALOII_03572 2.6e-157 rsbQ S Alpha/beta hydrolase family
LEMALOII_03573 1.4e-199 rsbU 3.1.3.3 T response regulator
LEMALOII_03574 2.6e-252 galA 3.2.1.89 G arabinogalactan
LEMALOII_03575 0.0 lacA 3.2.1.23 G beta-galactosidase
LEMALOII_03576 3.2e-150 ganQ P transport
LEMALOII_03577 1.3e-232 malC P COG1175 ABC-type sugar transport systems, permease components
LEMALOII_03578 2.9e-232 cycB G COG2182 Maltose-binding periplasmic proteins domains
LEMALOII_03579 1.8e-184 lacR K Transcriptional regulator
LEMALOII_03580 1e-112 yvfI K COG2186 Transcriptional regulators
LEMALOII_03581 1.4e-309 yvfH C L-lactate permease
LEMALOII_03582 6.5e-243 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
LEMALOII_03583 1e-31 yvfG S YvfG protein
LEMALOII_03584 5.8e-188 yvfF GM Exopolysaccharide biosynthesis protein
LEMALOII_03585 1.2e-224 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
LEMALOII_03586 2.2e-58 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
LEMALOII_03587 2.6e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
LEMALOII_03588 8.9e-260 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LEMALOII_03589 1.9e-197 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
LEMALOII_03590 3.6e-207 epsI GM pyruvyl transferase
LEMALOII_03591 3.6e-196 epsH GT2 S Glycosyltransferase like family 2
LEMALOII_03592 4.8e-207 epsG S EpsG family
LEMALOII_03593 5.3e-220 epsF GT4 M Glycosyl transferases group 1
LEMALOII_03594 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LEMALOII_03595 2e-224 epsD GT4 M Glycosyl transferase 4-like
LEMALOII_03596 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
LEMALOII_03597 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
LEMALOII_03598 4e-122 ywqC M biosynthesis protein
LEMALOII_03599 5.7e-77 slr K transcriptional
LEMALOII_03600 4.8e-287 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
LEMALOII_03602 4.6e-93 padC Q Phenolic acid decarboxylase
LEMALOII_03603 1.3e-48 MA20_18690 S Protein of unknown function (DUF3237)
LEMALOII_03604 3.1e-127 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
LEMALOII_03605 9.6e-266 pbpE V Beta-lactamase
LEMALOII_03606 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
LEMALOII_03607 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
LEMALOII_03608 1.8e-295 yveA E amino acid
LEMALOII_03609 2.6e-106 yvdT K Transcriptional regulator
LEMALOII_03610 6.7e-51 ykkC P Small Multidrug Resistance protein
LEMALOII_03611 4.1e-50 sugE P Small Multidrug Resistance protein
LEMALOII_03612 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
LEMALOII_03613 8.4e-270 ygaK C COG0277 FAD FMN-containing dehydrogenases
LEMALOII_03614 1.5e-183 S Patatin-like phospholipase
LEMALOII_03616 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LEMALOII_03617 3.9e-90 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
LEMALOII_03618 7.4e-19 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
LEMALOII_03619 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
LEMALOII_03620 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
LEMALOII_03621 1.2e-158 malA S Protein of unknown function (DUF1189)
LEMALOII_03622 7.8e-149 malD P transport
LEMALOII_03623 5.3e-245 malC P COG1175 ABC-type sugar transport systems, permease components
LEMALOII_03624 1.3e-235 mdxE G COG2182 Maltose-binding periplasmic proteins domains
LEMALOII_03625 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
LEMALOII_03626 3.6e-174 yvdE K Transcriptional regulator
LEMALOII_03627 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
LEMALOII_03628 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
LEMALOII_03629 2.1e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
LEMALOII_03630 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
LEMALOII_03631 1.3e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEMALOII_03632 0.0 yxdM V ABC transporter (permease)
LEMALOII_03633 5.6e-141 yvcR V ABC transporter, ATP-binding protein
LEMALOII_03634 2.3e-198 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
LEMALOII_03635 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEMALOII_03636 1.8e-33
LEMALOII_03637 8.6e-147 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
LEMALOII_03638 1.6e-36 crh G Phosphocarrier protein Chr
LEMALOII_03639 1.4e-170 whiA K May be required for sporulation
LEMALOII_03640 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
LEMALOII_03641 5.7e-166 rapZ S Displays ATPase and GTPase activities
LEMALOII_03642 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
LEMALOII_03643 1.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LEMALOII_03644 1.4e-102 usp CBM50 M protein conserved in bacteria
LEMALOII_03645 2.4e-278 S COG0457 FOG TPR repeat
LEMALOII_03646 0.0 msbA2 3.6.3.44 V ABC transporter
LEMALOII_03648 0.0
LEMALOII_03649 4.6e-121
LEMALOII_03650 8e-114 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
LEMALOII_03651 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
LEMALOII_03652 3.1e-133 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LEMALOII_03653 1.7e-116 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LEMALOII_03654 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
LEMALOII_03655 6.6e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LEMALOII_03656 1.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
LEMALOII_03657 4.8e-221 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LEMALOII_03658 4.5e-140 yvpB NU protein conserved in bacteria
LEMALOII_03659 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
LEMALOII_03660 3e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
LEMALOII_03661 1.3e-119 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
LEMALOII_03662 1.5e-164 yvoD P COG0370 Fe2 transport system protein B
LEMALOII_03663 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LEMALOII_03664 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LEMALOII_03665 6.8e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
LEMALOII_03666 8.9e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LEMALOII_03667 3.6e-134 yvoA K transcriptional
LEMALOII_03668 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
LEMALOII_03669 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
LEMALOII_03670 8.2e-232 cypX 1.14.15.13 C Cytochrome P450
LEMALOII_03671 1.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
LEMALOII_03672 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
LEMALOII_03673 2.7e-203 yvmA EGP Major facilitator Superfamily
LEMALOII_03674 1.2e-50 yvlD S Membrane
LEMALOII_03675 2.6e-26 pspB KT PspC domain
LEMALOII_03676 3.4e-168 yvlB S Putative adhesin
LEMALOII_03677 8e-49 yvlA
LEMALOII_03678 6.7e-34 yvkN
LEMALOII_03679 2.9e-79 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LEMALOII_03680 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LEMALOII_03681 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LEMALOII_03682 1.2e-30 csbA S protein conserved in bacteria
LEMALOII_03683 0.0 yvkC 2.7.9.2 GT Phosphotransferase
LEMALOII_03684 7e-101 yvkB K Transcriptional regulator
LEMALOII_03685 7.9e-228 yvkA EGP Major facilitator Superfamily
LEMALOII_03686 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LEMALOII_03687 5.3e-56 swrA S Swarming motility protein
LEMALOII_03688 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
LEMALOII_03689 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
LEMALOII_03690 1.6e-123 ftsE D cell division ATP-binding protein FtsE
LEMALOII_03691 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
LEMALOII_03692 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
LEMALOII_03693 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LEMALOII_03694 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LEMALOII_03695 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LEMALOII_03696 2.8e-66
LEMALOII_03697 1.9e-08 fliT S bacterial-type flagellum organization
LEMALOII_03698 2.9e-69 fliS N flagellar protein FliS
LEMALOII_03699 1.3e-266 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LEMALOII_03700 6.1e-57 flaG N flagellar protein FlaG
LEMALOII_03701 1.9e-156 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LEMALOII_03702 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LEMALOII_03703 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
LEMALOII_03704 2.6e-50 yviE
LEMALOII_03705 1.1e-156 flgL N Belongs to the bacterial flagellin family
LEMALOII_03706 1.2e-264 flgK N flagellar hook-associated protein
LEMALOII_03707 2.4e-78 flgN NOU FlgN protein
LEMALOII_03708 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
LEMALOII_03709 7e-74 yvyF S flagellar protein
LEMALOII_03710 2.7e-129 comFC S Phosphoribosyl transferase domain
LEMALOII_03711 5.7e-46 comFB S Late competence development protein ComFB
LEMALOII_03712 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LEMALOII_03713 7.3e-155 degV S protein conserved in bacteria
LEMALOII_03714 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LEMALOII_03715 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
LEMALOII_03716 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
LEMALOII_03717 6e-163 yvhJ K Transcriptional regulator
LEMALOII_03718 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
LEMALOII_03719 4.4e-238 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
LEMALOII_03720 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
LEMALOII_03721 6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
LEMALOII_03722 1.7e-263 tuaE M Teichuronic acid biosynthesis protein
LEMALOII_03723 2.4e-259 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LEMALOII_03724 7.4e-222 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
LEMALOII_03725 3.3e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LEMALOII_03726 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
LEMALOII_03727 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LEMALOII_03728 0.0 lytB 3.5.1.28 D Stage II sporulation protein
LEMALOII_03729 6e-38
LEMALOII_03730 6.1e-163 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
LEMALOII_03731 8.2e-218 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LEMALOII_03732 9e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
LEMALOII_03733 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
LEMALOII_03734 8.1e-257 ggaA M Glycosyltransferase like family 2
LEMALOII_03736 1.6e-100 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
LEMALOII_03737 1.8e-279 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
LEMALOII_03738 1.1e-150 tagG GM Transport permease protein
LEMALOII_03739 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LEMALOII_03740 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
LEMALOII_03741 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
LEMALOII_03742 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
LEMALOII_03743 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LEMALOII_03744 1.2e-260
LEMALOII_03745 7.2e-217 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LEMALOII_03746 7.1e-191 pmi 5.3.1.8 G mannose-6-phosphate isomerase
LEMALOII_03747 3.5e-266 gerBA EG Spore germination protein
LEMALOII_03748 7.5e-200 gerBB E Spore germination protein
LEMALOII_03749 7.6e-216 gerAC S Spore germination protein
LEMALOII_03750 1.9e-248 ywtG EGP Major facilitator Superfamily
LEMALOII_03751 8.4e-171 ywtF K Transcriptional regulator
LEMALOII_03752 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
LEMALOII_03753 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
LEMALOII_03754 3.6e-21 ywtC
LEMALOII_03755 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
LEMALOII_03756 8.6e-70 pgsC S biosynthesis protein
LEMALOII_03757 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
LEMALOII_03758 1.9e-178 rbsR K transcriptional
LEMALOII_03759 2.9e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LEMALOII_03760 2.8e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
LEMALOII_03761 2.3e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
LEMALOII_03762 1.4e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
LEMALOII_03763 4.4e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
LEMALOII_03764 4.6e-94 batE T Sh3 type 3 domain protein
LEMALOII_03765 3.6e-48 ywsA S Protein of unknown function (DUF3892)
LEMALOII_03766 1.5e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
LEMALOII_03767 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
LEMALOII_03768 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
LEMALOII_03769 1.1e-169 alsR K LysR substrate binding domain
LEMALOII_03770 1.9e-220 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LEMALOII_03771 7.5e-126 ywrJ
LEMALOII_03772 7.6e-131 cotB
LEMALOII_03773 1.2e-210 cotH M Spore Coat
LEMALOII_03774 3.7e-12
LEMALOII_03775 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LEMALOII_03776 2.9e-54 S Domain of unknown function (DUF4181)
LEMALOII_03777 9.6e-310 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
LEMALOII_03778 2.1e-82 ywrC K Transcriptional regulator
LEMALOII_03779 2.4e-104 ywrB P Chromate transporter
LEMALOII_03780 6.9e-90 ywrA P COG2059 Chromate transport protein ChrA
LEMALOII_03782 2.7e-102 ywqN S NAD(P)H-dependent
LEMALOII_03783 2.9e-162 K Transcriptional regulator
LEMALOII_03784 4.5e-137 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
LEMALOII_03785 1.7e-52 S MORN repeat variant
LEMALOII_03786 0.0 ywqJ L nucleic acid phosphodiester bond hydrolysis
LEMALOII_03787 1.3e-38 ywqI S Family of unknown function (DUF5344)
LEMALOII_03788 3.3e-15 S Domain of unknown function (DUF5082)
LEMALOII_03789 3.4e-154 ywqG S Domain of unknown function (DUF1963)
LEMALOII_03790 3e-248 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LEMALOII_03791 1.4e-141 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
LEMALOII_03792 1.1e-119 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
LEMALOII_03793 2e-116 ywqC M biosynthesis protein
LEMALOII_03794 1.2e-17
LEMALOII_03795 3.8e-309 ywqB S SWIM zinc finger
LEMALOII_03796 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
LEMALOII_03797 3.6e-157 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
LEMALOII_03798 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
LEMALOII_03799 9.8e-58 ssbB L Single-stranded DNA-binding protein
LEMALOII_03800 1.3e-66 ywpG
LEMALOII_03801 1.1e-66 ywpF S YwpF-like protein
LEMALOII_03802 8e-51 srtA 3.4.22.70 M Sortase family
LEMALOII_03803 1.9e-153 ywpD T Histidine kinase
LEMALOII_03804 1.5e-54 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LEMALOII_03805 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LEMALOII_03806 2.1e-199 S aspartate phosphatase
LEMALOII_03807 1.5e-141 flhP N flagellar basal body
LEMALOII_03808 6.9e-126 flhO N flagellar basal body
LEMALOII_03809 3.5e-180 mbl D Rod shape-determining protein
LEMALOII_03810 3e-44 spoIIID K Stage III sporulation protein D
LEMALOII_03811 2.1e-70 ywoH K COG1846 Transcriptional regulators
LEMALOII_03812 2.7e-211 ywoG EGP Major facilitator Superfamily
LEMALOII_03813 1.2e-231 ywoF P Right handed beta helix region
LEMALOII_03814 3e-281 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
LEMALOII_03815 4.4e-242 ywoD EGP Major facilitator superfamily
LEMALOII_03816 4e-104 phzA Q Isochorismatase family
LEMALOII_03817 1.2e-77
LEMALOII_03818 2.5e-225 amt P Ammonium transporter
LEMALOII_03819 1.6e-58 nrgB K Belongs to the P(II) protein family
LEMALOII_03820 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
LEMALOII_03821 3.5e-73 ywnJ S VanZ like family
LEMALOII_03822 5.5e-126 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
LEMALOII_03823 6.4e-90 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
LEMALOII_03824 2.7e-14 ywnC S Family of unknown function (DUF5362)
LEMALOII_03825 2.2e-70 ywnF S Family of unknown function (DUF5392)
LEMALOII_03826 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LEMALOII_03827 4.1e-144 mta K transcriptional
LEMALOII_03828 2.6e-59 ywnC S Family of unknown function (DUF5362)
LEMALOII_03829 1.6e-114 ywnB S NAD(P)H-binding
LEMALOII_03830 1.7e-64 ywnA K Transcriptional regulator
LEMALOII_03831 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
LEMALOII_03832 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
LEMALOII_03833 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
LEMALOII_03835 3.8e-11 csbD K CsbD-like
LEMALOII_03836 3e-84 ywmF S Peptidase M50
LEMALOII_03837 1.3e-103 S response regulator aspartate phosphatase
LEMALOII_03838 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LEMALOII_03839 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LEMALOII_03841 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
LEMALOII_03842 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
LEMALOII_03843 2e-178 spoIID D Stage II sporulation protein D
LEMALOII_03844 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LEMALOII_03845 1.6e-134 ywmB S TATA-box binding
LEMALOII_03846 1.3e-32 ywzB S membrane
LEMALOII_03847 4.3e-88 ywmA
LEMALOII_03848 5.9e-54 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
LEMALOII_03849 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LEMALOII_03850 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LEMALOII_03851 6.9e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LEMALOII_03852 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LEMALOII_03853 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LEMALOII_03854 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LEMALOII_03855 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
LEMALOII_03856 2.5e-62 atpI S ATP synthase
LEMALOII_03857 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LEMALOII_03858 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LEMALOII_03859 7.2e-95 ywlG S Belongs to the UPF0340 family
LEMALOII_03860 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
LEMALOII_03861 1.7e-78 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LEMALOII_03862 1.7e-91 mntP P Probably functions as a manganese efflux pump
LEMALOII_03863 1.2e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LEMALOII_03864 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
LEMALOII_03865 6.1e-112 spoIIR S stage II sporulation protein R
LEMALOII_03866 3.4e-56 ywlA S Uncharacterised protein family (UPF0715)
LEMALOII_03868 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LEMALOII_03869 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LEMALOII_03870 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEMALOII_03871 1.7e-91 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
LEMALOII_03872 8.6e-160 ywkB S Membrane transport protein
LEMALOII_03873 0.0 sfcA 1.1.1.38 C malic enzyme
LEMALOII_03874 2.4e-104 tdk 2.7.1.21 F thymidine kinase
LEMALOII_03875 1.1e-32 rpmE J Binds the 23S rRNA
LEMALOII_03876 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LEMALOII_03877 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
LEMALOII_03878 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LEMALOII_03879 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LEMALOII_03880 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
LEMALOII_03881 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
LEMALOII_03882 2.4e-92 ywjG S Domain of unknown function (DUF2529)
LEMALOII_03883 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LEMALOII_03884 1.5e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LEMALOII_03885 2.6e-211 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
LEMALOII_03886 0.0 fadF C COG0247 Fe-S oxidoreductase
LEMALOII_03887 2.3e-223 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
LEMALOII_03888 6.6e-184 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
LEMALOII_03889 2.7e-42 ywjC
LEMALOII_03890 4.8e-96 ywjB H RibD C-terminal domain
LEMALOII_03891 4.7e-180 ywjA V ABC transporter
LEMALOII_03892 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LEMALOII_03893 7e-86 arfM T cyclic nucleotide binding
LEMALOII_03894 4.3e-140 ywiC S YwiC-like protein
LEMALOII_03895 5.3e-130 fnr K helix_turn_helix, cAMP Regulatory protein
LEMALOII_03896 9.8e-214 narK P COG2223 Nitrate nitrite transporter
LEMALOII_03897 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
LEMALOII_03898 4.7e-73 ywiB S protein conserved in bacteria
LEMALOII_03899 1e-07 S Bacteriocin subtilosin A
LEMALOII_03900 2.6e-271 C Fe-S oxidoreductases
LEMALOII_03902 3.3e-132 cbiO V ABC transporter
LEMALOII_03903 3.1e-237 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
LEMALOII_03904 2.7e-219 2.7.1.26, 2.7.7.2 L Peptidase, M16
LEMALOII_03905 1.2e-249 L Peptidase, M16
LEMALOII_03907 2.9e-249 ywhL CO amine dehydrogenase activity
LEMALOII_03908 2.5e-205 ywhK CO amine dehydrogenase activity
LEMALOII_03909 2.3e-79 S aspartate phosphatase
LEMALOII_03911 1e-84 ywhH S Aminoacyl-tRNA editing domain
LEMALOII_03912 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
LEMALOII_03913 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LEMALOII_03914 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LEMALOII_03915 5.2e-95 ywhD S YwhD family
LEMALOII_03916 5.1e-119 ywhC S Peptidase family M50
LEMALOII_03917 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
LEMALOII_03918 3.3e-71 ywhA K Transcriptional regulator
LEMALOII_03919 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LEMALOII_03921 2.6e-242 mmr U Major Facilitator Superfamily
LEMALOII_03922 2.8e-79 yffB K Transcriptional regulator
LEMALOII_03923 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
LEMALOII_03924 1.8e-256 ywfO S COG1078 HD superfamily phosphohydrolases
LEMALOII_03925 3.1e-36 ywzC S Belongs to the UPF0741 family
LEMALOII_03926 1.6e-111 rsfA_1
LEMALOII_03927 5.2e-159 ywfM EG EamA-like transporter family
LEMALOII_03928 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
LEMALOII_03929 9.2e-164 cysL K Transcriptional regulator
LEMALOII_03930 6.6e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
LEMALOII_03931 1.1e-146 ywfI C May function as heme-dependent peroxidase
LEMALOII_03932 4e-139 IQ Enoyl-(Acyl carrier protein) reductase
LEMALOII_03933 2.7e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
LEMALOII_03934 2.9e-210 bacE EGP Major facilitator Superfamily
LEMALOII_03935 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
LEMALOII_03936 1.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEMALOII_03937 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
LEMALOII_03938 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
LEMALOII_03939 4.6e-206 ywfA EGP Major facilitator Superfamily
LEMALOII_03940 4e-262 lysP E amino acid
LEMALOII_03941 0.0 rocB E arginine degradation protein
LEMALOII_03942 1.4e-297 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
LEMALOII_03943 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
LEMALOII_03944 1.8e-78
LEMALOII_03945 3.5e-87 spsL 5.1.3.13 M Spore Coat
LEMALOII_03946 5.3e-161 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LEMALOII_03947 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LEMALOII_03948 1.9e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LEMALOII_03949 1.7e-190 spsG M Spore Coat
LEMALOII_03950 9.7e-132 spsF M Spore Coat
LEMALOII_03951 3.2e-214 spsE 2.5.1.56 M acid synthase
LEMALOII_03952 4e-164 spsD 2.3.1.210 K Spore Coat
LEMALOII_03953 1.6e-224 spsC E Belongs to the DegT DnrJ EryC1 family
LEMALOII_03954 1.5e-269 spsB M Capsule polysaccharide biosynthesis protein
LEMALOII_03955 2.8e-145 spsA M Spore Coat
LEMALOII_03956 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
LEMALOII_03957 4.3e-59 ywdK S small membrane protein
LEMALOII_03958 1.3e-238 ywdJ F Xanthine uracil
LEMALOII_03959 7.7e-49 ywdI S Family of unknown function (DUF5327)
LEMALOII_03960 5.9e-263 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
LEMALOII_03961 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LEMALOII_03962 1.1e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
LEMALOII_03964 1.4e-113 ywdD
LEMALOII_03965 1.3e-57 pex K Transcriptional regulator PadR-like family
LEMALOII_03966 9.3e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
LEMALOII_03967 2e-28 ywdA
LEMALOII_03968 9.5e-296 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
LEMALOII_03969 3.9e-254 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LEMALOII_03970 1e-139 focA P Formate/nitrite transporter
LEMALOII_03971 2.4e-150 sacT K transcriptional antiterminator
LEMALOII_03973 0.0 vpr O Belongs to the peptidase S8 family
LEMALOII_03974 5.1e-187 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LEMALOII_03975 7.2e-138 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
LEMALOII_03976 2.9e-202 rodA D Belongs to the SEDS family
LEMALOII_03977 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
LEMALOII_03978 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
LEMALOII_03979 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
LEMALOII_03980 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LEMALOII_03981 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
LEMALOII_03982 1e-35 ywzA S membrane
LEMALOII_03983 3.7e-306 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
LEMALOII_03984 6.2e-229 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LEMALOII_03985 9.5e-60 gtcA S GtrA-like protein
LEMALOII_03986 2.2e-122 ywcC K transcriptional regulator
LEMALOII_03988 9.8e-49 ywcB S Protein of unknown function, DUF485
LEMALOII_03989 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LEMALOII_03990 1.9e-112 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
LEMALOII_03991 2.6e-225 ywbN P Dyp-type peroxidase family protein
LEMALOII_03992 2e-187 ycdO P periplasmic lipoprotein involved in iron transport
LEMALOII_03993 8.2e-255 P COG0672 High-affinity Fe2 Pb2 permease
LEMALOII_03994 4.1e-116 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
LEMALOII_03995 2.8e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LEMALOII_03996 4.3e-153 ywbI K Transcriptional regulator
LEMALOII_03997 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
LEMALOII_03998 2.3e-111 ywbG M effector of murein hydrolase
LEMALOII_03999 1.9e-209 ywbF EGP Major facilitator Superfamily
LEMALOII_04000 1.2e-28 ywbE S Uncharacterized conserved protein (DUF2196)
LEMALOII_04001 8.9e-223 ywbD 2.1.1.191 J Methyltransferase
LEMALOII_04002 4.4e-67 ywbC 4.4.1.5 E glyoxalase
LEMALOII_04003 1.8e-127 ywbB S Protein of unknown function (DUF2711)
LEMALOII_04004 5.8e-247 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEMALOII_04005 1.6e-277 epr 3.4.21.62 O Belongs to the peptidase S8 family
LEMALOII_04006 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LEMALOII_04007 4e-153 sacY K transcriptional antiterminator
LEMALOII_04008 7e-169 gspA M General stress
LEMALOII_04009 1.7e-128 ywaF S Integral membrane protein
LEMALOII_04010 8.1e-88 ywaE K Transcriptional regulator
LEMALOII_04011 4.4e-233 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LEMALOII_04012 1.4e-251 ywaD 3.4.11.10, 3.4.11.6 S PA domain
LEMALOII_04013 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
LEMALOII_04014 5.4e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
LEMALOII_04015 5e-14 S D-Ala-teichoic acid biosynthesis protein
LEMALOII_04016 7.9e-293 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEMALOII_04017 1.2e-232 dltB M membrane protein involved in D-alanine export
LEMALOII_04018 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEMALOII_04019 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LEMALOII_04020 6.6e-139 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
LEMALOII_04021 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
LEMALOII_04022 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LEMALOII_04023 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
LEMALOII_04024 7.4e-250 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEMALOII_04025 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
LEMALOII_04026 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
LEMALOII_04027 1.1e-19 yxzF
LEMALOII_04028 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
LEMALOII_04029 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
LEMALOII_04030 2.1e-216 yxlH EGP Major facilitator Superfamily
LEMALOII_04031 1.8e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LEMALOII_04032 5.1e-167 yxlF V ABC transporter, ATP-binding protein
LEMALOII_04033 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
LEMALOII_04034 1.2e-31
LEMALOII_04035 3.9e-48 yxlC S Family of unknown function (DUF5345)
LEMALOII_04036 4.7e-91 sigY K Belongs to the sigma-70 factor family. ECF subfamily
LEMALOII_04037 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
LEMALOII_04038 8e-162 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LEMALOII_04039 0.0 cydD V ATP-binding protein
LEMALOII_04040 0.0 cydD V ATP-binding
LEMALOII_04041 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
LEMALOII_04042 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
LEMALOII_04043 1.5e-229 cimH C COG3493 Na citrate symporter
LEMALOII_04044 0.0 3.4.24.84 O Peptidase family M48
LEMALOII_04046 3e-156 yxkH G Polysaccharide deacetylase
LEMALOII_04047 5.9e-205 msmK P Belongs to the ABC transporter superfamily
LEMALOII_04048 4.8e-165 lrp QT PucR C-terminal helix-turn-helix domain
LEMALOII_04049 2.5e-275 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LEMALOII_04050 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LEMALOII_04051 4.1e-73 yxkC S Domain of unknown function (DUF4352)
LEMALOII_04052 4.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LEMALOII_04053 1.3e-95 yxkA S Phosphatidylethanolamine-binding protein
LEMALOII_04054 1.9e-166 yxjO K LysR substrate binding domain
LEMALOII_04055 2.4e-78 S Protein of unknown function (DUF1453)
LEMALOII_04056 1.5e-193 yxjM T Signal transduction histidine kinase
LEMALOII_04057 8.9e-116 K helix_turn_helix, Lux Regulon
LEMALOII_04058 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
LEMALOII_04061 1e-87 yxjI S LURP-one-related
LEMALOII_04062 5.5e-222 yxjG 2.1.1.14 E Methionine synthase
LEMALOII_04063 1e-220 yxjG 2.1.1.14 E Methionine synthase
LEMALOII_04064 1.3e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
LEMALOII_04065 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
LEMALOII_04066 1.4e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LEMALOII_04067 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
LEMALOII_04068 3.1e-161 rlmA 2.1.1.187 Q Methyltransferase domain
LEMALOII_04069 1.9e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LEMALOII_04070 1.2e-22 T Domain of unknown function (DUF4163)
LEMALOII_04071 2.7e-48 yxiS
LEMALOII_04072 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
LEMALOII_04073 6.6e-224 citH C Citrate transporter
LEMALOII_04074 5e-144 exoK GH16 M licheninase activity
LEMALOII_04075 8.3e-151 licT K transcriptional antiterminator
LEMALOII_04076 6.6e-114
LEMALOII_04077 3e-232 yxiO S COG2270 Permeases of the major facilitator superfamily
LEMALOII_04078 1e-265 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
LEMALOII_04079 7.5e-219 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
LEMALOII_04082 1.6e-48 yxiJ S YxiJ-like protein
LEMALOII_04083 1.2e-96 yxiI S Protein of unknown function (DUF2716)
LEMALOII_04084 3.8e-81
LEMALOII_04085 4.9e-46
LEMALOII_04086 3.7e-75 yxiG
LEMALOII_04087 7.1e-62
LEMALOII_04088 1.7e-84
LEMALOII_04089 1.5e-71 yxxG
LEMALOII_04090 0.0 wapA M COG3209 Rhs family protein
LEMALOII_04091 2.9e-168 yxxF EG EamA-like transporter family
LEMALOII_04092 1.1e-72 yxiE T Belongs to the universal stress protein A family
LEMALOII_04093 6.6e-281 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LEMALOII_04094 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LEMALOII_04095 3.6e-51
LEMALOII_04096 2.2e-78 S SMI1 / KNR4 family
LEMALOII_04097 0.0 S nuclease activity
LEMALOII_04098 3.6e-39 yxiC S Family of unknown function (DUF5344)
LEMALOII_04099 2.1e-21 S Domain of unknown function (DUF5082)
LEMALOII_04100 6.3e-284 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
LEMALOII_04101 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
LEMALOII_04102 2.3e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
LEMALOII_04103 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LEMALOII_04104 1.2e-238 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
LEMALOII_04105 8e-182 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
LEMALOII_04106 6.1e-252 lysP E amino acid
LEMALOII_04107 4.2e-234 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
LEMALOII_04108 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LEMALOII_04109 7e-116 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LEMALOII_04110 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LEMALOII_04111 3e-153 yxxB S Domain of Unknown Function (DUF1206)
LEMALOII_04112 6.8e-201 eutH E Ethanolamine utilisation protein, EutH
LEMALOII_04113 2e-255 yxeQ S MmgE/PrpD family
LEMALOII_04114 3.8e-215 yxeP 3.5.1.47 E hydrolase activity
LEMALOII_04115 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
LEMALOII_04116 5.4e-108 yxeN P COG0765 ABC-type amino acid transport system, permease component
LEMALOII_04117 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
LEMALOII_04118 7.3e-94 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LEMALOII_04119 2.2e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LEMALOII_04121 8.8e-192 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
LEMALOII_04122 6.2e-151 yidA S hydrolases of the HAD superfamily
LEMALOII_04125 1.3e-20 yxeE
LEMALOII_04126 1.9e-16 yxeD
LEMALOII_04127 8.5e-69
LEMALOII_04128 6e-177 fhuD P ABC transporter
LEMALOII_04129 1.5e-58 yxeA S Protein of unknown function (DUF1093)
LEMALOII_04130 0.0 yxdM V ABC transporter (permease)
LEMALOII_04131 9.4e-141 yxdL V ABC transporter, ATP-binding protein
LEMALOII_04132 1.3e-182 T PhoQ Sensor
LEMALOII_04133 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEMALOII_04134 5.4e-161 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
LEMALOII_04135 1.9e-139 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
LEMALOII_04136 2.3e-167 iolH G Xylose isomerase-like TIM barrel
LEMALOII_04137 2.8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
LEMALOII_04138 1.3e-235 iolF EGP Major facilitator Superfamily
LEMALOII_04139 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
LEMALOII_04140 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
LEMALOII_04141 2.9e-179 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
LEMALOII_04142 1.1e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
LEMALOII_04143 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LEMALOII_04144 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
LEMALOII_04145 3.7e-176 iolS C Aldo keto reductase
LEMALOII_04147 8.3e-48 yxcD S Protein of unknown function (DUF2653)
LEMALOII_04148 2.3e-246 csbC EGP Major facilitator Superfamily
LEMALOII_04149 0.0 htpG O Molecular chaperone. Has ATPase activity
LEMALOII_04151 5.7e-152 IQ Enoyl-(Acyl carrier protein) reductase
LEMALOII_04152 2.2e-215 yxbF K Bacterial regulatory proteins, tetR family
LEMALOII_04153 1.4e-248 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
LEMALOII_04154 1.6e-85 yxbD 3.2.2.20 K Acetyltransferase (GNAT) domain
LEMALOII_04155 2.2e-187 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
LEMALOII_04156 3.3e-127 yxbB Q Met-10+ like-protein
LEMALOII_04157 4.9e-44 S Coenzyme PQQ synthesis protein D (PqqD)
LEMALOII_04158 1.1e-86 yxnB
LEMALOII_04159 0.0 asnB 6.3.5.4 E Asparagine synthase
LEMALOII_04160 7.6e-214 yxaM U MFS_1 like family
LEMALOII_04161 6.8e-93 S PQQ-like domain
LEMALOII_04162 3.5e-65 S Family of unknown function (DUF5391)
LEMALOII_04163 1.1e-75 yxaI S membrane protein domain
LEMALOII_04164 1.4e-228 P Protein of unknown function (DUF418)
LEMALOII_04165 1.5e-199 yxaG 1.13.11.24 S AraC-like ligand binding domain
LEMALOII_04166 7.1e-101 yxaF K Transcriptional regulator
LEMALOII_04167 2.3e-201 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LEMALOII_04168 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
LEMALOII_04169 5.2e-50 S LrgA family
LEMALOII_04170 2.6e-118 yxaC M effector of murein hydrolase
LEMALOII_04171 1.3e-193 yxaB GM Polysaccharide pyruvyl transferase
LEMALOII_04172 7e-209 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
LEMALOII_04173 7.3e-127 gntR K transcriptional
LEMALOII_04174 4.6e-304 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
LEMALOII_04175 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
LEMALOII_04176 3.8e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LEMALOII_04177 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
LEMALOII_04178 3.8e-287 ahpF O Alkyl hydroperoxide reductase
LEMALOII_04179 6.4e-292 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LEMALOII_04180 2.5e-19 bglF G phosphotransferase system
LEMALOII_04181 1.3e-128 yydK K Transcriptional regulator
LEMALOII_04182 7.6e-13
LEMALOII_04183 3.3e-119 S ABC-2 family transporter protein
LEMALOII_04184 1.8e-110 prrC P ABC transporter
LEMALOII_04185 8.4e-134 yydH O Peptidase M50
LEMALOII_04186 7.7e-185 S Radical SAM superfamily
LEMALOII_04187 8e-12
LEMALOII_04188 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
LEMALOII_04189 0.0 S Uncharacterised protein conserved in bacteria (DUF2326)
LEMALOII_04190 3.5e-65
LEMALOII_04191 7.3e-280 S Calcineurin-like phosphoesterase
LEMALOII_04192 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LEMALOII_04193 1.1e-09 S YyzF-like protein
LEMALOII_04194 4.2e-71
LEMALOII_04195 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LEMALOII_04197 2.1e-33 yycQ S Protein of unknown function (DUF2651)
LEMALOII_04198 1.6e-221 yycP
LEMALOII_04199 5.8e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
LEMALOII_04200 3.1e-86 yycN 2.3.1.128 K Acetyltransferase
LEMALOII_04201 5e-188 S aspartate phosphatase
LEMALOII_04203 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
LEMALOII_04204 9.7e-261 rocE E amino acid
LEMALOII_04205 1.7e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
LEMALOII_04206 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
LEMALOII_04207 8.4e-221 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LEMALOII_04208 8.7e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
LEMALOII_04209 7.3e-155 yycI S protein conserved in bacteria
LEMALOII_04210 3.6e-260 yycH S protein conserved in bacteria
LEMALOII_04211 0.0 vicK 2.7.13.3 T Histidine kinase
LEMALOII_04212 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEMALOII_04217 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LEMALOII_04218 8e-78 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEMALOII_04219 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
LEMALOII_04220 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
LEMALOII_04222 1.9e-15 yycC K YycC-like protein
LEMALOII_04223 8.4e-221 yeaN P COG2807 Cyanate permease
LEMALOII_04224 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LEMALOII_04225 2.2e-73 rplI J binds to the 23S rRNA
LEMALOII_04226 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
LEMALOII_04227 2.9e-160 yybS S membrane
LEMALOII_04229 3.9e-84 cotF M Spore coat protein
LEMALOII_04230 1.4e-68 ydeP3 K Transcriptional regulator
LEMALOII_04231 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
LEMALOII_04232 1.3e-70
LEMALOII_04234 2.3e-240 yybO G COG0477 Permeases of the major facilitator superfamily
LEMALOII_04235 1e-16
LEMALOII_04236 1.3e-78 yybN S Protein of unknown function (DUF2712)
LEMALOII_04237 4.1e-125
LEMALOII_04238 9e-122
LEMALOII_04239 2e-127 S Protein of unknown function (DUF2705)
LEMALOII_04240 2.6e-115 V ATPases associated with a variety of cellular activities
LEMALOII_04241 6.2e-132
LEMALOII_04242 5.9e-67 yybH S SnoaL-like domain
LEMALOII_04243 3e-124 yybG S Pentapeptide repeat-containing protein
LEMALOII_04244 3.2e-220 ynfM EGP Major facilitator Superfamily
LEMALOII_04245 2.1e-165 yybE K Transcriptional regulator
LEMALOII_04246 2e-79 yjcF S Acetyltransferase (GNAT) domain
LEMALOII_04247 2.7e-77 yybC
LEMALOII_04248 3e-127 S Metallo-beta-lactamase superfamily
LEMALOII_04249 5.6e-77 yybA 2.3.1.57 K transcriptional
LEMALOII_04250 5.9e-79 yjcF S Acetyltransferase (GNAT) domain
LEMALOII_04251 1.5e-101 yyaS S Membrane
LEMALOII_04252 5.4e-100 yyaR K Acetyltransferase (GNAT) domain
LEMALOII_04253 5.4e-67 yyaQ S YjbR
LEMALOII_04254 1.7e-107 yyaP 1.5.1.3 H RibD C-terminal domain
LEMALOII_04255 1.7e-249 tetL EGP Major facilitator Superfamily
LEMALOII_04256 9.7e-44 yyaL O Highly conserved protein containing a thioredoxin domain
LEMALOII_04257 5.1e-61 yyaN K MerR HTH family regulatory protein
LEMALOII_04258 3.3e-161 yyaM EG EamA-like transporter family
LEMALOII_04259 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
LEMALOII_04260 9.5e-169 yyaK S CAAX protease self-immunity
LEMALOII_04261 3.8e-246 EGP Major facilitator superfamily
LEMALOII_04262 5.1e-96 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
LEMALOII_04263 4e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEMALOII_04264 3.3e-180 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
LEMALOII_04265 8.1e-145 xth 3.1.11.2 L exodeoxyribonuclease III
LEMALOII_04266 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LEMALOII_04267 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LEMALOII_04268 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
LEMALOII_04269 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LEMALOII_04270 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LEMALOII_04271 2.3e-33 yyzM S protein conserved in bacteria
LEMALOII_04272 8.1e-177 yyaD S Membrane
LEMALOII_04273 1.6e-111 yyaC S Sporulation protein YyaC
LEMALOII_04274 2.1e-149 spo0J K Belongs to the ParB family
LEMALOII_04275 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
LEMALOII_04276 1.5e-74 S Bacterial PH domain
LEMALOII_04277 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
LEMALOII_04278 2.2e-131 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
LEMALOII_04279 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LEMALOII_04280 3.1e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LEMALOII_04281 6.5e-108 jag S single-stranded nucleic acid binding R3H
LEMALOII_04282 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LEMALOII_04283 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LEMALOII_04288 1.2e-10 tdk 2.7.1.21 F Psort location Cytoplasmic, score
LEMALOII_04290 4e-15 repA S Replication initiator protein A (RepA) N-terminus
LEMALOII_04291 4.5e-184 S DNA gyrase B
LEMALOII_04292 3.5e-147 S DNA gyrase/topoisomerase IV, subunit A
LEMALOII_04293 1.5e-57 traC L Domain of unknown function (DUF1738)
LEMALOII_04300 5.4e-13 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
LEMALOII_04302 1e-24 S Domain of unknown function (DUF4935)
LEMALOII_04303 1.1e-106
LEMALOII_04304 1.5e-20 L COG3666 Transposase and inactivated derivatives
LEMALOII_04305 4.6e-61
LEMALOII_04307 1.5e-63 S Immunity protein 70
LEMALOII_04308 2.1e-174 A Pre-toxin TG
LEMALOII_04309 1.2e-97 S Phage integrase family
LEMALOII_04310 1.2e-106 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 CBM50 M Glycosyl hydrolases family 25
LEMALOII_04311 1.5e-09 S SPP1 phage holin
LEMALOII_04314 5.1e-12
LEMALOII_04315 5.4e-77 S N-acetylmuramoyl-L-alanine amidase activity
LEMALOII_04316 4e-23
LEMALOII_04317 2.4e-147 S Phage minor structural protein
LEMALOII_04318 6.7e-176 S Phage tail protein
LEMALOII_04319 1.5e-173 D Phage tail tape measure protein
LEMALOII_04321 1.6e-40 S Phage tail tube protein
LEMALOII_04322 1.9e-07
LEMALOII_04323 7.4e-14 S Bacteriophage HK97-gp10, putative tail-component
LEMALOII_04324 1.8e-11 S Phage head-tail joining protein
LEMALOII_04325 1.4e-21 S DNA packaging
LEMALOII_04327 6.8e-87 S Phage capsid family
LEMALOII_04328 1.5e-55 S Caudovirus prohead serine protease
LEMALOII_04329 7.1e-107 S Phage portal protein
LEMALOII_04330 1.1e-210 S Phage Terminase
LEMALOII_04333 8.1e-29 S Phage terminase, small subunit
LEMALOII_04336 3.8e-79
LEMALOII_04338 4.2e-69 lig 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP dependent DNA ligase domain
LEMALOII_04339 3.9e-21 yocH 3.5.1.28 M 3D domain
LEMALOII_04341 1.3e-69 L Phage integrase family
LEMALOII_04342 1.3e-52
LEMALOII_04345 2e-41 XK27_03185 S Phosphoribosyl-ATP pyrophosphohydrolase
LEMALOII_04346 6.2e-20
LEMALOII_04348 2.3e-32 yxcD S Protein of unknown function (DUF2653)
LEMALOII_04349 4.5e-07
LEMALOII_04351 2.5e-34
LEMALOII_04352 8.2e-48 F Nucleoside 2-deoxyribosyltransferase
LEMALOII_04355 1.9e-64 S AAA domain
LEMALOII_04356 1.5e-277 S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
LEMALOII_04357 1.2e-103 S Ribonucleotide reductase, small chain
LEMALOII_04358 3.4e-10 fld C flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
LEMALOII_04360 1e-39
LEMALOII_04362 2.3e-36
LEMALOII_04363 7.8e-16
LEMALOII_04364 3e-109 S DNA helicase activity
LEMALOII_04365 1e-89 S DNA primase activity
LEMALOII_04367 1.4e-86 S exonuclease activity
LEMALOII_04368 1.9e-15 K Transcriptional regulator
LEMALOII_04369 2.3e-17 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase like
LEMALOII_04371 6.1e-07 yfbR S HD containing hydrolase-like enzyme
LEMALOII_04374 1.8e-46 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LEMALOII_04376 4.4e-10 thyX 2.1.1.148 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant
LEMALOII_04378 0.0 S Bacterial DNA polymerase III alpha subunit
LEMALOII_04382 2.8e-22 2.7.4.8 F Guanylate kinase homologues.
LEMALOII_04383 4.3e-18 S Endodeoxyribonuclease RusA

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)