ORF_ID e_value Gene_name EC_number CAZy COGs Description
HEBFMCMF_00001 1.3e-235 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HEBFMCMF_00002 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HEBFMCMF_00003 2.4e-33 yaaA S S4 domain
HEBFMCMF_00004 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HEBFMCMF_00005 1.8e-37 yaaB S Domain of unknown function (DUF370)
HEBFMCMF_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEBFMCMF_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEBFMCMF_00008 3.4e-39 S COG NOG14552 non supervised orthologous group
HEBFMCMF_00011 6.7e-181 yaaC S YaaC-like Protein
HEBFMCMF_00012 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HEBFMCMF_00013 1.5e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HEBFMCMF_00014 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HEBFMCMF_00015 2.3e-107 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HEBFMCMF_00016 1.2e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HEBFMCMF_00017 1.3e-09
HEBFMCMF_00018 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
HEBFMCMF_00019 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
HEBFMCMF_00020 3.6e-214 yaaH M Glycoside Hydrolase Family
HEBFMCMF_00021 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
HEBFMCMF_00022 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HEBFMCMF_00023 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEBFMCMF_00024 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HEBFMCMF_00025 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HEBFMCMF_00026 7.9e-32 yaaL S Protein of unknown function (DUF2508)
HEBFMCMF_00027 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
HEBFMCMF_00028 3.4e-39 S COG NOG14552 non supervised orthologous group
HEBFMCMF_00031 3.4e-31 csfB S Inhibitor of sigma-G Gin
HEBFMCMF_00032 2.4e-102 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HEBFMCMF_00033 1.4e-201 yaaN P Belongs to the TelA family
HEBFMCMF_00034 2.7e-274 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
HEBFMCMF_00035 1.4e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HEBFMCMF_00036 2.2e-54 yaaQ S protein conserved in bacteria
HEBFMCMF_00037 1.5e-71 yaaR S protein conserved in bacteria
HEBFMCMF_00038 1.1e-181 holB 2.7.7.7 L DNA polymerase III
HEBFMCMF_00039 6.1e-146 yaaT S stage 0 sporulation protein
HEBFMCMF_00040 4.8e-31 yabA L Involved in initiation control of chromosome replication
HEBFMCMF_00041 4.2e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
HEBFMCMF_00042 3.3e-49 yazA L endonuclease containing a URI domain
HEBFMCMF_00043 7.4e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HEBFMCMF_00044 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
HEBFMCMF_00045 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HEBFMCMF_00046 1.2e-143 tatD L hydrolase, TatD
HEBFMCMF_00047 4.3e-194 rpfB GH23 T protein conserved in bacteria
HEBFMCMF_00048 3.5e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HEBFMCMF_00049 1.2e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HEBFMCMF_00050 1.6e-136 yabG S peptidase
HEBFMCMF_00051 7.8e-39 veg S protein conserved in bacteria
HEBFMCMF_00052 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HEBFMCMF_00053 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HEBFMCMF_00054 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
HEBFMCMF_00055 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HEBFMCMF_00056 1.9e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HEBFMCMF_00057 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HEBFMCMF_00058 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HEBFMCMF_00059 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HEBFMCMF_00060 2.4e-39 yabK S Peptide ABC transporter permease
HEBFMCMF_00061 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HEBFMCMF_00062 1.5e-92 spoVT K stage V sporulation protein
HEBFMCMF_00063 1.6e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEBFMCMF_00064 4.3e-243 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HEBFMCMF_00065 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HEBFMCMF_00066 1.5e-49 yabP S Sporulation protein YabP
HEBFMCMF_00067 1.2e-106 yabQ S spore cortex biosynthesis protein
HEBFMCMF_00068 1.1e-44 divIC D Septum formation initiator
HEBFMCMF_00069 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
HEBFMCMF_00072 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
HEBFMCMF_00073 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
HEBFMCMF_00074 3.7e-185 KLT serine threonine protein kinase
HEBFMCMF_00075 3.8e-273 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HEBFMCMF_00076 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HEBFMCMF_00077 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HEBFMCMF_00078 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HEBFMCMF_00079 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HEBFMCMF_00080 1.3e-151 yacD 5.2.1.8 O peptidyl-prolyl isomerase
HEBFMCMF_00081 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HEBFMCMF_00082 1.7e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HEBFMCMF_00083 2.1e-105 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
HEBFMCMF_00084 8.7e-167 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
HEBFMCMF_00085 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HEBFMCMF_00086 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HEBFMCMF_00087 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HEBFMCMF_00088 4.1e-30 yazB K transcriptional
HEBFMCMF_00089 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEBFMCMF_00090 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HEBFMCMF_00091 3.4e-39 S COG NOG14552 non supervised orthologous group
HEBFMCMF_00096 2e-08
HEBFMCMF_00101 3.4e-39 S COG NOG14552 non supervised orthologous group
HEBFMCMF_00102 2.9e-76 ctsR K Belongs to the CtsR family
HEBFMCMF_00103 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
HEBFMCMF_00104 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HEBFMCMF_00105 0.0 clpC O Belongs to the ClpA ClpB family
HEBFMCMF_00106 6.2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HEBFMCMF_00107 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HEBFMCMF_00108 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
HEBFMCMF_00109 1.5e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HEBFMCMF_00110 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HEBFMCMF_00111 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HEBFMCMF_00112 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
HEBFMCMF_00113 3.2e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HEBFMCMF_00114 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HEBFMCMF_00115 2.6e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEBFMCMF_00116 1.2e-88 yacP S RNA-binding protein containing a PIN domain
HEBFMCMF_00117 4.4e-115 sigH K Belongs to the sigma-70 factor family
HEBFMCMF_00118 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HEBFMCMF_00119 4.9e-96 nusG K Participates in transcription elongation, termination and antitermination
HEBFMCMF_00120 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HEBFMCMF_00121 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HEBFMCMF_00122 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HEBFMCMF_00123 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HEBFMCMF_00124 3.1e-107 rsmC 2.1.1.172 J Methyltransferase
HEBFMCMF_00125 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEBFMCMF_00126 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEBFMCMF_00127 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
HEBFMCMF_00128 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HEBFMCMF_00129 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HEBFMCMF_00130 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HEBFMCMF_00131 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HEBFMCMF_00132 8.8e-181 ybaC 3.4.11.5 S Alpha/beta hydrolase family
HEBFMCMF_00133 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HEBFMCMF_00134 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HEBFMCMF_00135 3.9e-105 rplD J Forms part of the polypeptide exit tunnel
HEBFMCMF_00136 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HEBFMCMF_00137 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HEBFMCMF_00138 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HEBFMCMF_00139 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HEBFMCMF_00140 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HEBFMCMF_00141 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HEBFMCMF_00142 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HEBFMCMF_00143 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HEBFMCMF_00144 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HEBFMCMF_00145 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HEBFMCMF_00146 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HEBFMCMF_00147 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HEBFMCMF_00148 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HEBFMCMF_00149 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HEBFMCMF_00150 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HEBFMCMF_00151 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HEBFMCMF_00152 1.9e-23 rpmD J Ribosomal protein L30
HEBFMCMF_00153 1.8e-72 rplO J binds to the 23S rRNA
HEBFMCMF_00154 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HEBFMCMF_00155 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HEBFMCMF_00156 8.2e-142 map 3.4.11.18 E Methionine aminopeptidase
HEBFMCMF_00157 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HEBFMCMF_00158 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HEBFMCMF_00159 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HEBFMCMF_00160 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HEBFMCMF_00161 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEBFMCMF_00162 3.6e-58 rplQ J Ribosomal protein L17
HEBFMCMF_00163 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEBFMCMF_00164 5.4e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEBFMCMF_00165 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEBFMCMF_00166 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HEBFMCMF_00167 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HEBFMCMF_00168 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HEBFMCMF_00169 3.4e-143 ybaJ Q Methyltransferase domain
HEBFMCMF_00170 9.7e-66 ybaK S Protein of unknown function (DUF2521)
HEBFMCMF_00171 2.5e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HEBFMCMF_00172 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HEBFMCMF_00173 1.2e-84 gerD
HEBFMCMF_00174 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
HEBFMCMF_00175 2.7e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
HEBFMCMF_00176 3.4e-39 S COG NOG14552 non supervised orthologous group
HEBFMCMF_00179 2e-08
HEBFMCMF_00183 3.4e-39 S COG NOG14552 non supervised orthologous group
HEBFMCMF_00184 3.4e-39 S COG NOG14552 non supervised orthologous group
HEBFMCMF_00185 1.5e-245 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
HEBFMCMF_00187 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
HEBFMCMF_00188 4.1e-141 ybbA S Putative esterase
HEBFMCMF_00189 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEBFMCMF_00190 1.8e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEBFMCMF_00191 4e-165 feuA P Iron-uptake system-binding protein
HEBFMCMF_00192 1.2e-304 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
HEBFMCMF_00193 2.7e-238 ybbC 3.2.1.52 S protein conserved in bacteria
HEBFMCMF_00194 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
HEBFMCMF_00195 4.1e-253 yfeW 3.4.16.4 V Belongs to the UPF0214 family
HEBFMCMF_00196 3.7e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HEBFMCMF_00197 1.4e-150 ybbH K transcriptional
HEBFMCMF_00198 3e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HEBFMCMF_00199 4.1e-86 ybbJ J acetyltransferase
HEBFMCMF_00200 1.5e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
HEBFMCMF_00206 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
HEBFMCMF_00207 6.3e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HEBFMCMF_00208 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HEBFMCMF_00209 5.7e-224 ybbR S protein conserved in bacteria
HEBFMCMF_00210 9.3e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HEBFMCMF_00211 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HEBFMCMF_00212 6e-171 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HEBFMCMF_00213 9.8e-120 adaA 3.2.2.21 K Transcriptional regulator
HEBFMCMF_00214 3.3e-100 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HEBFMCMF_00215 8.8e-276 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HEBFMCMF_00216 0.0 ybcC S Belongs to the UPF0753 family
HEBFMCMF_00217 4.7e-91 can 4.2.1.1 P carbonic anhydrase
HEBFMCMF_00219 1.9e-46
HEBFMCMF_00220 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
HEBFMCMF_00221 5.1e-50 ybzH K Helix-turn-helix domain
HEBFMCMF_00222 4.5e-203 ybcL EGP Major facilitator Superfamily
HEBFMCMF_00224 9.1e-239 J 4Fe-4S single cluster domain
HEBFMCMF_00225 1.6e-277 V CAAX protease self-immunity
HEBFMCMF_00226 1.9e-135 skfE V ABC transporter
HEBFMCMF_00227 4e-248 skfF S ABC transporter
HEBFMCMF_00228 7.8e-91 C HEAT repeats
HEBFMCMF_00229 9.6e-79 txn CO Thioredoxin-like
HEBFMCMF_00230 1.2e-180 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HEBFMCMF_00231 3.8e-122 T Transcriptional regulatory protein, C terminal
HEBFMCMF_00232 2e-172 T His Kinase A (phospho-acceptor) domain
HEBFMCMF_00234 5.1e-139 KLT Protein tyrosine kinase
HEBFMCMF_00235 1.3e-151 ybdN
HEBFMCMF_00236 2.8e-213 ybdO S Domain of unknown function (DUF4885)
HEBFMCMF_00237 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
HEBFMCMF_00238 1.4e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
HEBFMCMF_00239 4.9e-30 ybxH S Family of unknown function (DUF5370)
HEBFMCMF_00240 8.8e-150 ybxI 3.5.2.6 V beta-lactamase
HEBFMCMF_00241 1.7e-245 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
HEBFMCMF_00242 4.9e-41 ybyB
HEBFMCMF_00243 1.8e-290 ybeC E amino acid
HEBFMCMF_00244 3.4e-163 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HEBFMCMF_00245 7.3e-258 glpT G -transporter
HEBFMCMF_00246 8.5e-35 S Protein of unknown function (DUF2651)
HEBFMCMF_00247 1.4e-170 ybfA 3.4.15.5 K FR47-like protein
HEBFMCMF_00248 1.9e-223 ybfB G COG0477 Permeases of the major facilitator superfamily
HEBFMCMF_00250 0.0 ybfG M Domain of unknown function (DUF1906)
HEBFMCMF_00251 8.8e-162 ybfH EG EamA-like transporter family
HEBFMCMF_00252 2.3e-145 msmR K AraC-like ligand binding domain
HEBFMCMF_00253 8e-148 draG 3.2.2.24 O ADP-ribosylglycohydrolase
HEBFMCMF_00254 1.8e-77 M nucleic acid phosphodiester bond hydrolysis
HEBFMCMF_00255 1.7e-210 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HEBFMCMF_00256 2e-177 mpr 3.4.21.19 M Belongs to the peptidase S1B family
HEBFMCMF_00258 1.8e-167 S Alpha/beta hydrolase family
HEBFMCMF_00259 9.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HEBFMCMF_00260 2.7e-85 ybfM S SNARE associated Golgi protein
HEBFMCMF_00261 8.1e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HEBFMCMF_00262 4.6e-45 ybfN
HEBFMCMF_00263 5.4e-253 S Erythromycin esterase
HEBFMCMF_00264 3.9e-192 yceA S Belongs to the UPF0176 family
HEBFMCMF_00265 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEBFMCMF_00266 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HEBFMCMF_00267 1.2e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HEBFMCMF_00268 4.9e-128 K UTRA
HEBFMCMF_00270 2.3e-201 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HEBFMCMF_00271 2.2e-260 mmuP E amino acid
HEBFMCMF_00272 2.3e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
HEBFMCMF_00274 1.4e-254 agcS E Sodium alanine symporter
HEBFMCMF_00275 2.9e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
HEBFMCMF_00276 8e-228 phoQ 2.7.13.3 T Histidine kinase
HEBFMCMF_00277 2.6e-169 glnL T Regulator
HEBFMCMF_00278 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
HEBFMCMF_00279 1.7e-271 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HEBFMCMF_00280 2.7e-255 gudP G COG0477 Permeases of the major facilitator superfamily
HEBFMCMF_00281 7.2e-269 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HEBFMCMF_00282 1.5e-124 ycbG K FCD
HEBFMCMF_00283 4.5e-296 garD 4.2.1.42, 4.2.1.7 G Altronate
HEBFMCMF_00284 3.7e-176 ycbJ S Macrolide 2'-phosphotransferase
HEBFMCMF_00285 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
HEBFMCMF_00286 1.4e-167 eamA1 EG spore germination
HEBFMCMF_00287 2.9e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEBFMCMF_00288 3.8e-168 T PhoQ Sensor
HEBFMCMF_00289 9.1e-167 ycbN V ABC transporter, ATP-binding protein
HEBFMCMF_00290 6.7e-114 S ABC-2 family transporter protein
HEBFMCMF_00291 8.2e-53 ycbP S Protein of unknown function (DUF2512)
HEBFMCMF_00292 1.3e-78 sleB 3.5.1.28 M Cell wall
HEBFMCMF_00293 1.9e-135 ycbR T vWA found in TerF C terminus
HEBFMCMF_00294 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
HEBFMCMF_00295 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HEBFMCMF_00296 4.4e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HEBFMCMF_00297 4.5e-120 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HEBFMCMF_00298 1.4e-201 ycbU E Selenocysteine lyase
HEBFMCMF_00299 5.8e-229 lmrB EGP the major facilitator superfamily
HEBFMCMF_00300 4.8e-102 yxaF K Transcriptional regulator
HEBFMCMF_00301 1.8e-201 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HEBFMCMF_00302 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HEBFMCMF_00303 2.1e-56 S RDD family
HEBFMCMF_00304 5.2e-198 yccF K DNA-templated transcriptional preinitiation complex assembly
HEBFMCMF_00305 1.8e-157 2.7.13.3 T GHKL domain
HEBFMCMF_00306 1.2e-126 lytR_2 T LytTr DNA-binding domain
HEBFMCMF_00307 1.2e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
HEBFMCMF_00308 2.7e-200 natB CP ABC-2 family transporter protein
HEBFMCMF_00309 6.6e-173 yccK C Aldo keto reductase
HEBFMCMF_00310 2.5e-176 ycdA S Domain of unknown function (DUF5105)
HEBFMCMF_00311 1.8e-270 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
HEBFMCMF_00312 1.9e-254 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
HEBFMCMF_00313 6.9e-92 cwlK M D-alanyl-D-alanine carboxypeptidase
HEBFMCMF_00314 5.5e-174 S response regulator aspartate phosphatase
HEBFMCMF_00315 1e-139 IQ Enoyl-(Acyl carrier protein) reductase
HEBFMCMF_00316 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
HEBFMCMF_00317 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
HEBFMCMF_00318 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HEBFMCMF_00319 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HEBFMCMF_00320 5.4e-189 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEBFMCMF_00321 2.5e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
HEBFMCMF_00322 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
HEBFMCMF_00323 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
HEBFMCMF_00324 1.4e-136 terC P Protein of unknown function (DUF475)
HEBFMCMF_00325 0.0 yceG S Putative component of 'biosynthetic module'
HEBFMCMF_00326 6.3e-191 yceH P Belongs to the TelA family
HEBFMCMF_00327 8.7e-218 naiP P Uncharacterised MFS-type transporter YbfB
HEBFMCMF_00328 7.4e-206 yceJ EGP Uncharacterised MFS-type transporter YbfB
HEBFMCMF_00329 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
HEBFMCMF_00330 2.2e-227 proV 3.6.3.32 E glycine betaine
HEBFMCMF_00331 8.5e-127 opuAB P glycine betaine
HEBFMCMF_00332 5.3e-164 opuAC E glycine betaine
HEBFMCMF_00333 1.9e-217 amhX S amidohydrolase
HEBFMCMF_00334 8.7e-257 ycgA S Membrane
HEBFMCMF_00335 4.1e-81 ycgB
HEBFMCMF_00336 1.9e-100 amyE 3.2.1.1 GH13 G alpha-amylase
HEBFMCMF_00337 1.2e-134 S Rhabdovirus spike glycoprotein
HEBFMCMF_00338 4.2e-126 catB 2.3.1.28 V Chloramphenicol acetyltransferase
HEBFMCMF_00339 9.3e-197 amyE 3.2.1.1 GH13 G alpha-amylase
HEBFMCMF_00340 4.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HEBFMCMF_00341 3.9e-290 lctP C L-lactate permease
HEBFMCMF_00342 1.8e-260 mdr EGP Major facilitator Superfamily
HEBFMCMF_00343 2.9e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
HEBFMCMF_00344 2e-112 ycgF E Lysine exporter protein LysE YggA
HEBFMCMF_00345 7.6e-151 yqcI S YqcI/YcgG family
HEBFMCMF_00346 8.1e-249 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
HEBFMCMF_00347 2.4e-112 ycgI S Domain of unknown function (DUF1989)
HEBFMCMF_00348 5.8e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HEBFMCMF_00349 1.4e-107 tmrB S AAA domain
HEBFMCMF_00350 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HEBFMCMF_00351 7.6e-143 yafE Q ubiE/COQ5 methyltransferase family
HEBFMCMF_00352 7.9e-177 oxyR3 K LysR substrate binding domain
HEBFMCMF_00353 8e-182 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HEBFMCMF_00354 2.4e-144 ycgL S Predicted nucleotidyltransferase
HEBFMCMF_00355 5.1e-170 ycgM E Proline dehydrogenase
HEBFMCMF_00356 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HEBFMCMF_00357 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEBFMCMF_00358 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
HEBFMCMF_00359 1.3e-146 ycgQ S membrane
HEBFMCMF_00360 1.2e-139 ycgR S permeases
HEBFMCMF_00361 4.6e-157 I alpha/beta hydrolase fold
HEBFMCMF_00362 6.9e-192 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HEBFMCMF_00363 8.7e-273 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HEBFMCMF_00364 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
HEBFMCMF_00365 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HEBFMCMF_00366 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEBFMCMF_00367 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
HEBFMCMF_00368 1.7e-221 nasA P COG2223 Nitrate nitrite transporter
HEBFMCMF_00369 1.4e-172 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
HEBFMCMF_00370 2.7e-108 yciB M ErfK YbiS YcfS YnhG
HEBFMCMF_00371 2e-227 yciC S GTPases (G3E family)
HEBFMCMF_00372 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
HEBFMCMF_00373 1.4e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HEBFMCMF_00374 7.8e-52 yckD S Protein of unknown function (DUF2680)
HEBFMCMF_00375 5.7e-39 K MarR family
HEBFMCMF_00376 9.3e-24
HEBFMCMF_00377 7.1e-09 S AAA domain
HEBFMCMF_00378 2.8e-97 S AAA domain
HEBFMCMF_00379 6.3e-292 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HEBFMCMF_00380 1.1e-68 nin S Competence protein J (ComJ)
HEBFMCMF_00381 3e-70 nucA M Deoxyribonuclease NucA/NucB
HEBFMCMF_00382 3.6e-185 tlpC 2.7.13.3 NT chemotaxis protein
HEBFMCMF_00383 6.7e-96 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
HEBFMCMF_00384 3.6e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
HEBFMCMF_00385 1.3e-63 hxlR K transcriptional
HEBFMCMF_00386 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEBFMCMF_00387 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEBFMCMF_00388 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
HEBFMCMF_00389 6.4e-139 srfAD Q thioesterase
HEBFMCMF_00390 5.7e-225 EGP Major Facilitator Superfamily
HEBFMCMF_00391 1.1e-87 S YcxB-like protein
HEBFMCMF_00392 2.6e-161 ycxC EG EamA-like transporter family
HEBFMCMF_00393 5.6e-250 ycxD K GntR family transcriptional regulator
HEBFMCMF_00394 1.9e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HEBFMCMF_00395 1.7e-114 yczE S membrane
HEBFMCMF_00396 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HEBFMCMF_00397 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
HEBFMCMF_00398 1.3e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HEBFMCMF_00399 4.9e-162 bsdA K LysR substrate binding domain
HEBFMCMF_00400 3.7e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HEBFMCMF_00401 1.2e-282 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HEBFMCMF_00402 4e-39 bsdD 4.1.1.61 S response to toxic substance
HEBFMCMF_00403 2.3e-81 yclD
HEBFMCMF_00404 1.9e-158 yclE 3.4.11.5 S Alpha beta hydrolase
HEBFMCMF_00405 5.8e-264 dtpT E amino acid peptide transporter
HEBFMCMF_00406 2.7e-308 yclG M Pectate lyase superfamily protein
HEBFMCMF_00408 1.5e-281 gerKA EG Spore germination protein
HEBFMCMF_00409 1.3e-232 gerKC S spore germination
HEBFMCMF_00410 1.3e-199 gerKB F Spore germination protein
HEBFMCMF_00411 3.9e-122 yclH P ABC transporter
HEBFMCMF_00412 3.9e-204 yclI V ABC transporter (permease) YclI
HEBFMCMF_00413 4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEBFMCMF_00414 1.4e-259 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HEBFMCMF_00415 3.1e-71 S aspartate phosphatase
HEBFMCMF_00419 5.7e-250 lysC 2.7.2.4 E Belongs to the aspartokinase family
HEBFMCMF_00420 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEBFMCMF_00421 1.3e-163 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEBFMCMF_00422 1.1e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
HEBFMCMF_00423 1.4e-170 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
HEBFMCMF_00424 4.1e-251 ycnB EGP Major facilitator Superfamily
HEBFMCMF_00425 5.5e-153 ycnC K Transcriptional regulator
HEBFMCMF_00426 2.2e-134 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
HEBFMCMF_00427 1.6e-45 ycnE S Monooxygenase
HEBFMCMF_00428 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
HEBFMCMF_00429 1.5e-272 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEBFMCMF_00430 3.1e-245 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEBFMCMF_00431 3.8e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HEBFMCMF_00432 6.1e-149 glcU U Glucose uptake
HEBFMCMF_00433 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEBFMCMF_00434 1.4e-99 ycnI S protein conserved in bacteria
HEBFMCMF_00435 2.1e-307 ycnJ P protein, homolog of Cu resistance protein CopC
HEBFMCMF_00436 4.3e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
HEBFMCMF_00437 7.3e-56
HEBFMCMF_00438 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
HEBFMCMF_00439 5.7e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HEBFMCMF_00440 1.5e-208 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
HEBFMCMF_00441 4.7e-199 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
HEBFMCMF_00442 4.1e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HEBFMCMF_00443 1.7e-75 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HEBFMCMF_00444 1.4e-107 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
HEBFMCMF_00445 1.2e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HEBFMCMF_00447 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HEBFMCMF_00448 2.3e-139 ycsF S Belongs to the UPF0271 (lamB) family
HEBFMCMF_00449 1.6e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
HEBFMCMF_00450 4e-147 ycsI S Belongs to the D-glutamate cyclase family
HEBFMCMF_00451 1.9e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
HEBFMCMF_00452 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HEBFMCMF_00453 1.2e-132 kipR K Transcriptional regulator
HEBFMCMF_00454 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
HEBFMCMF_00456 1.4e-49 yczJ S biosynthesis
HEBFMCMF_00457 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
HEBFMCMF_00458 9.8e-174 ydhF S Oxidoreductase
HEBFMCMF_00459 0.0 mtlR K transcriptional regulator, MtlR
HEBFMCMF_00460 6.7e-292 ydaB IQ acyl-CoA ligase
HEBFMCMF_00461 6.9e-99 ydaC Q Methyltransferase domain
HEBFMCMF_00462 1.2e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEBFMCMF_00463 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
HEBFMCMF_00464 1e-101 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HEBFMCMF_00465 2e-76 ydaG 1.4.3.5 S general stress protein
HEBFMCMF_00466 3.5e-138 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HEBFMCMF_00467 3.3e-46 ydzA EGP Major facilitator Superfamily
HEBFMCMF_00468 2.5e-74 lrpC K Transcriptional regulator
HEBFMCMF_00469 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HEBFMCMF_00470 2.4e-206 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
HEBFMCMF_00471 1.1e-150 ydaK T Diguanylate cyclase, GGDEF domain
HEBFMCMF_00472 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
HEBFMCMF_00473 1.3e-232 ydaM M Glycosyl transferase family group 2
HEBFMCMF_00474 0.0 ydaN S Bacterial cellulose synthase subunit
HEBFMCMF_00475 0.0 ydaO E amino acid
HEBFMCMF_00476 1e-66 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HEBFMCMF_00477 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HEBFMCMF_00478 4.7e-39
HEBFMCMF_00479 1e-224 mntH P H( )-stimulated, divalent metal cation uptake system
HEBFMCMF_00481 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
HEBFMCMF_00482 2.3e-145 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
HEBFMCMF_00484 2.6e-58 ydbB G Cupin domain
HEBFMCMF_00485 1.5e-61 ydbC S Domain of unknown function (DUF4937
HEBFMCMF_00486 6.7e-153 ydbD P Catalase
HEBFMCMF_00487 7.9e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HEBFMCMF_00488 8.1e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HEBFMCMF_00489 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
HEBFMCMF_00490 1.4e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEBFMCMF_00491 9.7e-181 ydbI S AI-2E family transporter
HEBFMCMF_00492 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
HEBFMCMF_00493 1.6e-124 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HEBFMCMF_00494 2.7e-52 ydbL
HEBFMCMF_00495 3.4e-219 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
HEBFMCMF_00496 1.1e-18 S Fur-regulated basic protein B
HEBFMCMF_00497 2.2e-07 S Fur-regulated basic protein A
HEBFMCMF_00498 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEBFMCMF_00499 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HEBFMCMF_00500 3.3e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HEBFMCMF_00501 5.3e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HEBFMCMF_00502 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HEBFMCMF_00503 2.1e-82 ydbS S Bacterial PH domain
HEBFMCMF_00504 3.9e-260 ydbT S Membrane
HEBFMCMF_00505 1.2e-106 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
HEBFMCMF_00506 2.1e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HEBFMCMF_00507 5.5e-182 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
HEBFMCMF_00508 1.9e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HEBFMCMF_00509 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HEBFMCMF_00510 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
HEBFMCMF_00511 3.7e-143 rsbR T Positive regulator of sigma-B
HEBFMCMF_00512 5.2e-57 rsbS T antagonist
HEBFMCMF_00513 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HEBFMCMF_00514 9.3e-189 rsbU 3.1.3.3 KT phosphatase
HEBFMCMF_00515 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
HEBFMCMF_00516 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HEBFMCMF_00517 1.7e-137 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEBFMCMF_00518 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
HEBFMCMF_00519 0.0 yhgF K COG2183 Transcriptional accessory protein
HEBFMCMF_00520 3.4e-82 ydcK S Belongs to the SprT family
HEBFMCMF_00528 1.7e-75 rimJ2 J Acetyltransferase (GNAT) domain
HEBFMCMF_00529 4.2e-44
HEBFMCMF_00530 1.8e-20 S LXG domain of WXG superfamily
HEBFMCMF_00531 8.1e-24 L HNH endonuclease
HEBFMCMF_00532 6.4e-45 L HNH nucleases
HEBFMCMF_00535 8e-10
HEBFMCMF_00538 5.6e-34 K Helix-turn-helix XRE-family like proteins
HEBFMCMF_00539 2.5e-40
HEBFMCMF_00543 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HEBFMCMF_00544 8.7e-30 cspL K Cold shock
HEBFMCMF_00545 3e-78 carD K Transcription factor
HEBFMCMF_00546 2.1e-144 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HEBFMCMF_00547 3.6e-165 rhaS5 K AraC-like ligand binding domain
HEBFMCMF_00548 3.4e-172 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HEBFMCMF_00549 3.1e-164 ydeE K AraC family transcriptional regulator
HEBFMCMF_00550 5.6e-261 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEBFMCMF_00551 7.9e-217 ydeG EGP Major facilitator superfamily
HEBFMCMF_00552 8.8e-44 ydeH
HEBFMCMF_00553 1.3e-102 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
HEBFMCMF_00554 5.9e-107
HEBFMCMF_00555 2.8e-30 S SNARE associated Golgi protein
HEBFMCMF_00556 8.3e-15 ptsH G PTS HPr component phosphorylation site
HEBFMCMF_00557 8.8e-85 K Transcriptional regulator C-terminal region
HEBFMCMF_00558 1.8e-153 ydeK EG -transporter
HEBFMCMF_00559 2.4e-272 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEBFMCMF_00560 4.2e-74 maoC I N-terminal half of MaoC dehydratase
HEBFMCMF_00561 9.5e-106 ydeN S Serine hydrolase
HEBFMCMF_00562 2.2e-54 K HxlR-like helix-turn-helix
HEBFMCMF_00563 3.9e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HEBFMCMF_00564 4.8e-69 ydeP K Transcriptional regulator
HEBFMCMF_00565 3.6e-108 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
HEBFMCMF_00566 8.1e-192 ydeR EGP Major facilitator Superfamily
HEBFMCMF_00567 7.8e-103 ydeS K Transcriptional regulator
HEBFMCMF_00568 6.3e-57 arsR K transcriptional
HEBFMCMF_00569 2.6e-231 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HEBFMCMF_00570 3.4e-146 ydfB J GNAT acetyltransferase
HEBFMCMF_00571 8.5e-157 ydfC EG EamA-like transporter family
HEBFMCMF_00572 6e-274 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEBFMCMF_00573 5e-116 ydfE S Flavin reductase like domain
HEBFMCMF_00574 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
HEBFMCMF_00575 1.7e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HEBFMCMF_00577 1.8e-175 ydfH 2.7.13.3 T Histidine kinase
HEBFMCMF_00578 9.3e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEBFMCMF_00579 0.0 ydfJ S drug exporters of the RND superfamily
HEBFMCMF_00580 8.1e-176 S Alpha/beta hydrolase family
HEBFMCMF_00581 8.5e-117 S Protein of unknown function (DUF554)
HEBFMCMF_00582 1.2e-143 K Bacterial transcription activator, effector binding domain
HEBFMCMF_00583 7.8e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEBFMCMF_00584 1.2e-109 ydfN C nitroreductase
HEBFMCMF_00585 3.4e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
HEBFMCMF_00586 8.8e-63 mhqP S DoxX
HEBFMCMF_00587 7e-56 traF CO Thioredoxin
HEBFMCMF_00588 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
HEBFMCMF_00589 6.3e-29
HEBFMCMF_00591 4.4e-118 ydfR S Protein of unknown function (DUF421)
HEBFMCMF_00592 5.2e-122 ydfS S Protein of unknown function (DUF421)
HEBFMCMF_00593 1.7e-75 cotP O Belongs to the small heat shock protein (HSP20) family
HEBFMCMF_00594 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
HEBFMCMF_00595 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
HEBFMCMF_00596 5.3e-99 K Bacterial regulatory proteins, tetR family
HEBFMCMF_00597 2.4e-51 S DoxX-like family
HEBFMCMF_00598 1.9e-83 yycN 2.3.1.128 K Acetyltransferase
HEBFMCMF_00599 4e-298 expZ S ABC transporter
HEBFMCMF_00600 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HEBFMCMF_00601 1.3e-90 dinB S DinB family
HEBFMCMF_00602 1.8e-79 K helix_turn_helix multiple antibiotic resistance protein
HEBFMCMF_00603 0.0 ydgH S drug exporters of the RND superfamily
HEBFMCMF_00604 2.3e-113 drgA C nitroreductase
HEBFMCMF_00605 2.4e-69 ydgJ K Winged helix DNA-binding domain
HEBFMCMF_00606 1.6e-208 tcaB EGP Major facilitator Superfamily
HEBFMCMF_00607 3.5e-121 ydhB S membrane transporter protein
HEBFMCMF_00608 2.5e-121 ydhC K FCD
HEBFMCMF_00609 2.8e-243 ydhD M Glycosyl hydrolase
HEBFMCMF_00610 7.7e-227 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HEBFMCMF_00611 4.8e-123
HEBFMCMF_00612 2e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HEBFMCMF_00613 4.3e-67 frataxin S Domain of unknown function (DU1801)
HEBFMCMF_00615 3.6e-82 K Acetyltransferase (GNAT) domain
HEBFMCMF_00616 3.8e-179 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HEBFMCMF_00617 1.2e-97 ydhK M Protein of unknown function (DUF1541)
HEBFMCMF_00618 4.6e-200 pbuE EGP Major facilitator Superfamily
HEBFMCMF_00619 1.1e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
HEBFMCMF_00620 3e-51 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
HEBFMCMF_00621 2e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEBFMCMF_00622 7.3e-285 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HEBFMCMF_00623 1.1e-132 ydhQ K UTRA
HEBFMCMF_00624 2e-166 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
HEBFMCMF_00625 2.5e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
HEBFMCMF_00626 6.2e-215 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HEBFMCMF_00627 2.3e-156 ydhU P Catalase
HEBFMCMF_00630 3.4e-39 S COG NOG14552 non supervised orthologous group
HEBFMCMF_00631 7.8e-08
HEBFMCMF_00633 1.1e-178 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HEBFMCMF_00634 3.8e-84 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
HEBFMCMF_00635 2.9e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
HEBFMCMF_00636 1.1e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HEBFMCMF_00637 3e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HEBFMCMF_00638 0.0 ydiF S ABC transporter
HEBFMCMF_00639 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HEBFMCMF_00640 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HEBFMCMF_00641 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HEBFMCMF_00642 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HEBFMCMF_00643 2.9e-27 ydiK S Domain of unknown function (DUF4305)
HEBFMCMF_00644 2.3e-128 ydiL S CAAX protease self-immunity
HEBFMCMF_00645 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HEBFMCMF_00646 3.7e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HEBFMCMF_00647 2.8e-144 L Belongs to the 'phage' integrase family
HEBFMCMF_00648 4.2e-49 xkdA E IrrE N-terminal-like domain
HEBFMCMF_00649 8.9e-22 S Short C-terminal domain
HEBFMCMF_00650 1.1e-20 xre K transcriptional
HEBFMCMF_00652 2e-33
HEBFMCMF_00653 7.7e-44 S DNA binding
HEBFMCMF_00654 5.4e-69
HEBFMCMF_00659 6.9e-98
HEBFMCMF_00660 2.6e-69 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
HEBFMCMF_00662 6.5e-48 L DnaD domain protein
HEBFMCMF_00663 2.6e-80 xkdC L IstB-like ATP binding protein
HEBFMCMF_00665 1.5e-12 S YopX protein
HEBFMCMF_00666 9.3e-43 S Protein of unknown function (DUF1064)
HEBFMCMF_00668 4.2e-27 yqaO S Phage-like element PBSX protein XtrA
HEBFMCMF_00671 3.3e-59
HEBFMCMF_00673 2e-12 S YopX protein
HEBFMCMF_00679 1.9e-80 L Transposase
HEBFMCMF_00682 1.1e-82 yqaS L DNA packaging
HEBFMCMF_00683 6.6e-216 S phage terminase, large subunit
HEBFMCMF_00684 1.4e-206 S Phage portal protein, SPP1 Gp6-like
HEBFMCMF_00685 4.5e-81 S Phage Mu protein F like protein
HEBFMCMF_00688 2.3e-59 S Domain of unknown function (DUF4355)
HEBFMCMF_00689 3.5e-142 S Phage capsid family
HEBFMCMF_00692 2.4e-28 S Phage gp6-like head-tail connector protein
HEBFMCMF_00693 8.2e-28 S Phage head-tail joining protein
HEBFMCMF_00694 1.5e-36 S Bacteriophage HK97-gp10, putative tail-component
HEBFMCMF_00695 3.8e-29 S Protein of unknown function (DUF3168)
HEBFMCMF_00696 8.7e-34 S Phage tail tube protein
HEBFMCMF_00697 1.8e-09 chiA 3.2.1.14 GH18 G Glycosyl hydrolases family 18
HEBFMCMF_00698 7.1e-28 S Phage tail assembly chaperone protein, TAC
HEBFMCMF_00699 1.6e-179
HEBFMCMF_00700 2e-50
HEBFMCMF_00701 1.3e-221 S peptidoglycan catabolic process
HEBFMCMF_00706 1.9e-27 xhlA S Haemolysin XhlA
HEBFMCMF_00707 3.5e-31 xhlB S SPP1 phage holin
HEBFMCMF_00708 1.3e-131 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
HEBFMCMF_00709 3.2e-36
HEBFMCMF_00710 9e-19
HEBFMCMF_00713 3.5e-27 K Helix-turn-helix domain
HEBFMCMF_00714 5.1e-61 S guanosine tetraphosphate metabolic process
HEBFMCMF_00715 3.5e-92
HEBFMCMF_00716 1.7e-14
HEBFMCMF_00717 5.8e-151 ydjC S Abhydrolase domain containing 18
HEBFMCMF_00718 0.0 K NB-ARC domain
HEBFMCMF_00719 4.7e-199 gutB 1.1.1.14 E Dehydrogenase
HEBFMCMF_00720 4.3e-253 gutA G MFS/sugar transport protein
HEBFMCMF_00721 1.5e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
HEBFMCMF_00722 1.3e-112 pspA KT Phage shock protein A
HEBFMCMF_00723 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HEBFMCMF_00724 3.4e-135 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
HEBFMCMF_00725 4.1e-149 ydjI S virion core protein (lumpy skin disease virus)
HEBFMCMF_00726 3.3e-194 S Ion transport 2 domain protein
HEBFMCMF_00727 3.9e-257 iolT EGP Major facilitator Superfamily
HEBFMCMF_00728 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
HEBFMCMF_00729 4.5e-64 ydjM M Lytic transglycolase
HEBFMCMF_00730 6.3e-156 ydjN U Involved in the tonB-independent uptake of proteins
HEBFMCMF_00732 1.4e-34 ydjO S Cold-inducible protein YdjO
HEBFMCMF_00733 2.2e-156 ydjP I Alpha/beta hydrolase family
HEBFMCMF_00734 4.2e-178 yeaA S Protein of unknown function (DUF4003)
HEBFMCMF_00735 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
HEBFMCMF_00736 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
HEBFMCMF_00737 7.6e-155 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEBFMCMF_00738 3e-176 yeaC S COG0714 MoxR-like ATPases
HEBFMCMF_00739 3.1e-223 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HEBFMCMF_00740 0.0 yebA E COG1305 Transglutaminase-like enzymes
HEBFMCMF_00741 8.3e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HEBFMCMF_00742 6.4e-88 K Belongs to the sigma-70 factor family. ECF subfamily
HEBFMCMF_00743 9.8e-248 S Domain of unknown function (DUF4179)
HEBFMCMF_00744 1.5e-210 pbuG S permease
HEBFMCMF_00745 2.4e-115 yebC M Membrane
HEBFMCMF_00747 4e-93 yebE S UPF0316 protein
HEBFMCMF_00748 8e-28 yebG S NETI protein
HEBFMCMF_00749 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HEBFMCMF_00750 8.5e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HEBFMCMF_00751 2.8e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HEBFMCMF_00752 2.8e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HEBFMCMF_00753 8.4e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEBFMCMF_00754 9.5e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEBFMCMF_00755 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEBFMCMF_00756 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HEBFMCMF_00757 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HEBFMCMF_00758 3.7e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HEBFMCMF_00759 1.7e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HEBFMCMF_00760 7e-234 purD 6.3.4.13 F Belongs to the GARS family
HEBFMCMF_00761 1e-72 K helix_turn_helix ASNC type
HEBFMCMF_00762 2.8e-230 yjeH E Amino acid permease
HEBFMCMF_00763 2.7e-27 S Protein of unknown function (DUF2892)
HEBFMCMF_00764 0.0 yerA 3.5.4.2 F adenine deaminase
HEBFMCMF_00765 6.3e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
HEBFMCMF_00766 4.8e-51 yerC S protein conserved in bacteria
HEBFMCMF_00767 7.9e-304 yerD 1.4.7.1 E Belongs to the glutamate synthase family
HEBFMCMF_00768 6.4e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HEBFMCMF_00769 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HEBFMCMF_00770 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HEBFMCMF_00771 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
HEBFMCMF_00772 3.5e-196 yerI S homoserine kinase type II (protein kinase fold)
HEBFMCMF_00773 1.6e-123 sapB S MgtC SapB transporter
HEBFMCMF_00774 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEBFMCMF_00775 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEBFMCMF_00776 3.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HEBFMCMF_00777 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEBFMCMF_00778 1.3e-148 yerO K Transcriptional regulator
HEBFMCMF_00779 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HEBFMCMF_00780 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HEBFMCMF_00781 1.4e-248 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEBFMCMF_00783 0.0 hsdM 2.1.1.72 V Type I restriction-modification system
HEBFMCMF_00784 7.2e-104 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
HEBFMCMF_00785 0.0 hsdR 3.1.21.3 L Type I restriction enzyme R protein N terminus (HSDR_N)
HEBFMCMF_00786 9.1e-49 S Protein of unknown function (DUF1643)
HEBFMCMF_00787 2.3e-35 S Protein of unknown function, DUF600
HEBFMCMF_00788 4e-81 S Protein of unknown function, DUF600
HEBFMCMF_00789 2.7e-286 L nucleic acid phosphodiester bond hydrolysis
HEBFMCMF_00790 2e-32 L nucleic acid phosphodiester bond hydrolysis
HEBFMCMF_00791 1.2e-172 3.4.24.40 CO amine dehydrogenase activity
HEBFMCMF_00792 1.4e-53
HEBFMCMF_00793 2.1e-51
HEBFMCMF_00794 2.8e-15 S Lysozyme inhibitor LprI
HEBFMCMF_00795 4.8e-210 S Tetratricopeptide repeat
HEBFMCMF_00797 2.7e-126 yeeN K transcriptional regulatory protein
HEBFMCMF_00799 8.5e-102 dhaR3 K Transcriptional regulator
HEBFMCMF_00800 9.7e-82 yesE S SnoaL-like domain
HEBFMCMF_00801 1.3e-151 yesF GM NAD(P)H-binding
HEBFMCMF_00802 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
HEBFMCMF_00803 1.5e-45 cotJB S CotJB protein
HEBFMCMF_00804 5.2e-104 cotJC P Spore Coat
HEBFMCMF_00805 1.2e-102 yesJ K Acetyltransferase (GNAT) family
HEBFMCMF_00806 5.9e-101 yesL S Protein of unknown function, DUF624
HEBFMCMF_00807 0.0 yesM 2.7.13.3 T Histidine kinase
HEBFMCMF_00808 8e-202 yesN K helix_turn_helix, arabinose operon control protein
HEBFMCMF_00809 3.3e-247 yesO G Bacterial extracellular solute-binding protein
HEBFMCMF_00810 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
HEBFMCMF_00811 1.2e-163 yesQ P Binding-protein-dependent transport system inner membrane component
HEBFMCMF_00812 1.1e-197 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
HEBFMCMF_00813 0.0 yesS K Transcriptional regulator
HEBFMCMF_00814 7.9e-131 E GDSL-like Lipase/Acylhydrolase
HEBFMCMF_00815 2.7e-128 yesU S Domain of unknown function (DUF1961)
HEBFMCMF_00816 3.3e-112 yesV S Protein of unknown function, DUF624
HEBFMCMF_00817 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HEBFMCMF_00818 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HEBFMCMF_00819 7.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
HEBFMCMF_00820 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
HEBFMCMF_00821 0.0 yetA
HEBFMCMF_00822 1.1e-289 lplA G Bacterial extracellular solute-binding protein
HEBFMCMF_00823 1.6e-174 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HEBFMCMF_00824 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
HEBFMCMF_00825 1.2e-252 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HEBFMCMF_00826 8.8e-122 yetF S membrane
HEBFMCMF_00827 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HEBFMCMF_00828 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEBFMCMF_00829 2.4e-34
HEBFMCMF_00830 1.3e-143 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HEBFMCMF_00831 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
HEBFMCMF_00832 9.1e-105 yetJ S Belongs to the BI1 family
HEBFMCMF_00833 1.4e-89 yetL K helix_turn_helix multiple antibiotic resistance protein
HEBFMCMF_00834 9.8e-208 yetM CH FAD binding domain
HEBFMCMF_00835 3.6e-199 yetN S Protein of unknown function (DUF3900)
HEBFMCMF_00836 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HEBFMCMF_00837 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HEBFMCMF_00838 1e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
HEBFMCMF_00839 1.2e-185 yfnG 4.2.1.45 M dehydratase
HEBFMCMF_00840 4.2e-180 yfnF M Nucleotide-diphospho-sugar transferase
HEBFMCMF_00841 4.7e-224 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
HEBFMCMF_00842 1e-189 yfnD M Nucleotide-diphospho-sugar transferase
HEBFMCMF_00843 6e-206 fsr P COG0477 Permeases of the major facilitator superfamily
HEBFMCMF_00844 6.2e-131 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HEBFMCMF_00845 8.4e-241 yfnA E amino acid
HEBFMCMF_00846 3.7e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HEBFMCMF_00847 2.4e-113 yfmS NT chemotaxis protein
HEBFMCMF_00848 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HEBFMCMF_00849 6.8e-75 yfmQ S Uncharacterised protein from bacillus cereus group
HEBFMCMF_00850 1.4e-69 yfmP K transcriptional
HEBFMCMF_00851 9.5e-209 yfmO EGP Major facilitator Superfamily
HEBFMCMF_00852 2.1e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HEBFMCMF_00853 5e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
HEBFMCMF_00854 3.1e-80 yfmK 2.3.1.128 K acetyltransferase
HEBFMCMF_00855 2.7e-188 yfmJ S N-terminal domain of oxidoreductase
HEBFMCMF_00856 2.2e-213 G Major Facilitator Superfamily
HEBFMCMF_00857 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
HEBFMCMF_00858 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
HEBFMCMF_00859 3.1e-168 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEBFMCMF_00860 1.4e-168 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEBFMCMF_00861 7.9e-166 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HEBFMCMF_00862 5e-24 S Protein of unknown function (DUF3212)
HEBFMCMF_00863 7.6e-58 yflT S Heat induced stress protein YflT
HEBFMCMF_00864 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
HEBFMCMF_00865 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
HEBFMCMF_00866 2.6e-289 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HEBFMCMF_00867 2.2e-117 citT T response regulator
HEBFMCMF_00868 2.2e-179 yflP S Tripartite tricarboxylate transporter family receptor
HEBFMCMF_00869 8.5e-227 citM C Citrate transporter
HEBFMCMF_00870 1.5e-149 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
HEBFMCMF_00871 5.6e-216 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HEBFMCMF_00872 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HEBFMCMF_00873 9.9e-123 yflK S protein conserved in bacteria
HEBFMCMF_00874 4e-18 yflJ S Protein of unknown function (DUF2639)
HEBFMCMF_00875 4.1e-19 yflI
HEBFMCMF_00876 1.5e-49 yflH S Protein of unknown function (DUF3243)
HEBFMCMF_00877 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
HEBFMCMF_00878 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HEBFMCMF_00879 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HEBFMCMF_00880 6e-67 yhdN S Domain of unknown function (DUF1992)
HEBFMCMF_00881 2.2e-252 agcS_1 E Sodium alanine symporter
HEBFMCMF_00882 4e-27 yfkQ EG Spore germination protein
HEBFMCMF_00883 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HEBFMCMF_00884 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HEBFMCMF_00885 1.8e-133 treR K transcriptional
HEBFMCMF_00886 1.1e-124 yfkO C nitroreductase
HEBFMCMF_00887 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HEBFMCMF_00888 3.6e-88 yfkM 1.11.1.6, 3.5.1.124 S protease
HEBFMCMF_00889 8.9e-207 ydiM EGP Major facilitator Superfamily
HEBFMCMF_00890 2.1e-29 yfkK S Belongs to the UPF0435 family
HEBFMCMF_00891 1e-81 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HEBFMCMF_00892 2.4e-50 yfkI S gas vesicle protein
HEBFMCMF_00893 8.2e-143 yihY S Belongs to the UPF0761 family
HEBFMCMF_00894 5e-08
HEBFMCMF_00895 1.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
HEBFMCMF_00896 1.8e-182 cax P COG0387 Ca2 H antiporter
HEBFMCMF_00897 1.2e-146 yfkD S YfkD-like protein
HEBFMCMF_00898 7.8e-149 yfkC M Mechanosensitive ion channel
HEBFMCMF_00899 5.4e-222 yfkA S YfkB-like domain
HEBFMCMF_00900 1.1e-26 yfjT
HEBFMCMF_00901 2.6e-154 pdaA G deacetylase
HEBFMCMF_00902 2.2e-146 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HEBFMCMF_00903 1.7e-184 corA P Mediates influx of magnesium ions
HEBFMCMF_00904 1.3e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HEBFMCMF_00905 4e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEBFMCMF_00906 5.1e-44 S YfzA-like protein
HEBFMCMF_00907 1.1e-189 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEBFMCMF_00908 9.6e-85 yfjM S Psort location Cytoplasmic, score
HEBFMCMF_00909 6.6e-29 yfjL
HEBFMCMF_00910 4.4e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HEBFMCMF_00911 3.8e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HEBFMCMF_00912 3.5e-195 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HEBFMCMF_00913 1.5e-253 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HEBFMCMF_00914 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
HEBFMCMF_00915 9.8e-25 sspH S Belongs to the SspH family
HEBFMCMF_00916 9.7e-55 yfjF S UPF0060 membrane protein
HEBFMCMF_00917 5.1e-88 S Family of unknown function (DUF5381)
HEBFMCMF_00918 1.2e-124 yfjC
HEBFMCMF_00919 1.4e-170 yfjB
HEBFMCMF_00920 1.1e-44 yfjA S Belongs to the WXG100 family
HEBFMCMF_00921 1.4e-261 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HEBFMCMF_00922 6e-140 glvR K Helix-turn-helix domain, rpiR family
HEBFMCMF_00923 6.8e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HEBFMCMF_00924 6.4e-307 yfiB3 V ABC transporter
HEBFMCMF_00925 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
HEBFMCMF_00926 6.4e-64 mhqP S DoxX
HEBFMCMF_00927 2.8e-162 yfiE 1.13.11.2 S glyoxalase
HEBFMCMF_00929 4.9e-210 yxjM T Histidine kinase
HEBFMCMF_00930 1e-111 KT LuxR family transcriptional regulator
HEBFMCMF_00931 7.6e-169 V ABC transporter, ATP-binding protein
HEBFMCMF_00932 1.6e-208 V ABC-2 family transporter protein
HEBFMCMF_00933 9.9e-203 V COG0842 ABC-type multidrug transport system, permease component
HEBFMCMF_00934 8.3e-99 padR K transcriptional
HEBFMCMF_00935 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HEBFMCMF_00936 4.5e-197 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HEBFMCMF_00937 4.7e-99 yfiT S Belongs to the metal hydrolase YfiT family
HEBFMCMF_00938 1.4e-284 yfiU EGP Major facilitator Superfamily
HEBFMCMF_00939 5.8e-80 yfiV K transcriptional
HEBFMCMF_00940 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HEBFMCMF_00941 1.8e-176 yfiY P ABC transporter substrate-binding protein
HEBFMCMF_00942 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEBFMCMF_00943 6.8e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEBFMCMF_00944 1.1e-166 yfhB 5.3.3.17 S PhzF family
HEBFMCMF_00945 1.5e-106 yfhC C nitroreductase
HEBFMCMF_00946 2.1e-25 yfhD S YfhD-like protein
HEBFMCMF_00948 1.6e-171 yfhF S nucleoside-diphosphate sugar epimerase
HEBFMCMF_00949 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
HEBFMCMF_00950 9.7e-52 yfhH S Protein of unknown function (DUF1811)
HEBFMCMF_00952 1.1e-209 yfhI EGP Major facilitator Superfamily
HEBFMCMF_00953 6.2e-20 sspK S reproduction
HEBFMCMF_00954 2.9e-44 yfhJ S WVELL protein
HEBFMCMF_00955 2.4e-87 batE T Bacterial SH3 domain homologues
HEBFMCMF_00956 3.5e-51 yfhL S SdpI/YhfL protein family
HEBFMCMF_00957 1.3e-170 yfhM S Alpha beta hydrolase
HEBFMCMF_00958 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HEBFMCMF_00959 0.0 yfhO S Bacterial membrane protein YfhO
HEBFMCMF_00960 1.2e-185 yfhP S membrane-bound metal-dependent
HEBFMCMF_00961 3.3e-210 mutY L A G-specific
HEBFMCMF_00962 6.9e-36 yfhS
HEBFMCMF_00963 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEBFMCMF_00964 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
HEBFMCMF_00965 1.5e-37 ygaB S YgaB-like protein
HEBFMCMF_00966 1.3e-104 ygaC J Belongs to the UPF0374 family
HEBFMCMF_00967 1.8e-301 ygaD V ABC transporter
HEBFMCMF_00968 8.7e-180 ygaE S Membrane
HEBFMCMF_00969 2.1e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HEBFMCMF_00970 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
HEBFMCMF_00971 4e-80 perR P Belongs to the Fur family
HEBFMCMF_00972 9.5e-56 ygzB S UPF0295 protein
HEBFMCMF_00973 6.7e-167 ygxA S Nucleotidyltransferase-like
HEBFMCMF_00974 3.4e-39 S COG NOG14552 non supervised orthologous group
HEBFMCMF_00979 7.8e-08
HEBFMCMF_00987 2e-08
HEBFMCMF_00991 2.7e-143 spo0M S COG4326 Sporulation control protein
HEBFMCMF_00992 3e-27
HEBFMCMF_00993 1.3e-133 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
HEBFMCMF_00995 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HEBFMCMF_00996 3.8e-262 ygaK C Berberine and berberine like
HEBFMCMF_00998 1e-289 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HEBFMCMF_00999 2.5e-138 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HEBFMCMF_01000 1.6e-169 ssuA M Sulfonate ABC transporter
HEBFMCMF_01001 4.2e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HEBFMCMF_01002 2e-216 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
HEBFMCMF_01004 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HEBFMCMF_01005 4.1e-78 ygaO
HEBFMCMF_01006 4.4e-29 K Transcriptional regulator
HEBFMCMF_01008 7.9e-114 yhzB S B3/4 domain
HEBFMCMF_01009 7.8e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HEBFMCMF_01010 1.7e-176 yhbB S Putative amidase domain
HEBFMCMF_01011 9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HEBFMCMF_01012 6e-109 yhbD K Protein of unknown function (DUF4004)
HEBFMCMF_01013 2.5e-63 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
HEBFMCMF_01014 9.4e-71 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
HEBFMCMF_01015 0.0 prkA T Ser protein kinase
HEBFMCMF_01016 2.5e-225 yhbH S Belongs to the UPF0229 family
HEBFMCMF_01017 2.2e-76 yhbI K DNA-binding transcription factor activity
HEBFMCMF_01018 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
HEBFMCMF_01019 3.1e-271 yhcA EGP Major facilitator Superfamily
HEBFMCMF_01020 1.4e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
HEBFMCMF_01021 1.4e-36 yhcC
HEBFMCMF_01022 1.3e-54
HEBFMCMF_01023 1.9e-59 yhcF K Transcriptional regulator
HEBFMCMF_01024 4e-122 yhcG V ABC transporter, ATP-binding protein
HEBFMCMF_01025 6.5e-165 yhcH V ABC transporter, ATP-binding protein
HEBFMCMF_01026 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HEBFMCMF_01027 1e-30 cspB K Cold-shock protein
HEBFMCMF_01028 5.2e-153 metQ M Belongs to the nlpA lipoprotein family
HEBFMCMF_01029 3.4e-197 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
HEBFMCMF_01030 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEBFMCMF_01031 2.9e-41 yhcM
HEBFMCMF_01032 6e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HEBFMCMF_01033 1.2e-139 yhcP
HEBFMCMF_01034 5.2e-100 yhcQ M Spore coat protein
HEBFMCMF_01035 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
HEBFMCMF_01036 4.2e-104 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HEBFMCMF_01037 1.5e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HEBFMCMF_01038 2.1e-67 yhcU S Family of unknown function (DUF5365)
HEBFMCMF_01039 9.9e-68 yhcV S COG0517 FOG CBS domain
HEBFMCMF_01040 4.6e-120 yhcW 5.4.2.6 S hydrolase
HEBFMCMF_01041 6.6e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HEBFMCMF_01042 1.1e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEBFMCMF_01043 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HEBFMCMF_01044 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
HEBFMCMF_01045 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HEBFMCMF_01046 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HEBFMCMF_01047 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HEBFMCMF_01048 8e-213 yhcY 2.7.13.3 T Histidine kinase
HEBFMCMF_01049 1.7e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEBFMCMF_01050 9.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
HEBFMCMF_01051 1.2e-38 yhdB S YhdB-like protein
HEBFMCMF_01052 4.8e-54 yhdC S Protein of unknown function (DUF3889)
HEBFMCMF_01053 1.5e-187 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HEBFMCMF_01054 1e-75 nsrR K Transcriptional regulator
HEBFMCMF_01055 3.6e-237 ygxB M Conserved TM helix
HEBFMCMF_01056 2.1e-276 ycgB S Stage V sporulation protein R
HEBFMCMF_01057 2.4e-256 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HEBFMCMF_01058 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HEBFMCMF_01059 3.8e-162 citR K Transcriptional regulator
HEBFMCMF_01060 2.9e-204 citA 2.3.3.1 C Belongs to the citrate synthase family
HEBFMCMF_01061 1e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEBFMCMF_01062 1e-249 yhdG E amino acid
HEBFMCMF_01063 1.3e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HEBFMCMF_01064 3.6e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEBFMCMF_01065 5.9e-76 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEBFMCMF_01066 8.1e-45 yhdK S Sigma-M inhibitor protein
HEBFMCMF_01067 2.5e-200 yhdL S Sigma factor regulator N-terminal
HEBFMCMF_01068 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
HEBFMCMF_01069 7e-189 yhdN C Aldo keto reductase
HEBFMCMF_01070 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HEBFMCMF_01071 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HEBFMCMF_01072 4.1e-74 cueR K transcriptional
HEBFMCMF_01073 1.3e-221 yhdR 2.6.1.1 E Aminotransferase
HEBFMCMF_01074 2.5e-245 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
HEBFMCMF_01075 1.3e-44 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEBFMCMF_01076 2.8e-64 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEBFMCMF_01077 4e-133 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HEBFMCMF_01079 5.6e-203 yhdY M Mechanosensitive ion channel
HEBFMCMF_01080 3.8e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HEBFMCMF_01081 2.3e-148 yheN G deacetylase
HEBFMCMF_01082 9e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HEBFMCMF_01083 3.8e-230 nhaC C Na H antiporter
HEBFMCMF_01084 1.7e-83 nhaX T Belongs to the universal stress protein A family
HEBFMCMF_01085 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
HEBFMCMF_01086 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
HEBFMCMF_01087 5.8e-109 yheG GM NAD(P)H-binding
HEBFMCMF_01088 6.3e-28 sspB S spore protein
HEBFMCMF_01089 2.9e-36 yheE S Family of unknown function (DUF5342)
HEBFMCMF_01090 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
HEBFMCMF_01091 4.3e-216 yheC HJ YheC/D like ATP-grasp
HEBFMCMF_01092 1.8e-201 yheB S Belongs to the UPF0754 family
HEBFMCMF_01093 9.5e-48 yheA S Belongs to the UPF0342 family
HEBFMCMF_01094 1.5e-205 yhaZ L DNA alkylation repair enzyme
HEBFMCMF_01095 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
HEBFMCMF_01096 1.8e-292 hemZ H coproporphyrinogen III oxidase
HEBFMCMF_01097 2.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
HEBFMCMF_01098 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
HEBFMCMF_01100 9.4e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
HEBFMCMF_01101 1.6e-25 S YhzD-like protein
HEBFMCMF_01102 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
HEBFMCMF_01103 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
HEBFMCMF_01104 3.3e-225 yhaO L DNA repair exonuclease
HEBFMCMF_01105 0.0 yhaN L AAA domain
HEBFMCMF_01106 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
HEBFMCMF_01107 1.6e-21 yhaL S Sporulation protein YhaL
HEBFMCMF_01108 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HEBFMCMF_01109 8.7e-90 yhaK S Putative zincin peptidase
HEBFMCMF_01110 1.3e-54 yhaI S Protein of unknown function (DUF1878)
HEBFMCMF_01111 1e-113 hpr K Negative regulator of protease production and sporulation
HEBFMCMF_01112 7e-39 yhaH S YtxH-like protein
HEBFMCMF_01113 3.6e-80 trpP S Tryptophan transporter TrpP
HEBFMCMF_01114 7.1e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HEBFMCMF_01115 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HEBFMCMF_01116 1e-136 ecsA V transporter (ATP-binding protein)
HEBFMCMF_01117 7e-215 ecsB U ABC transporter
HEBFMCMF_01118 2e-113 ecsC S EcsC protein family
HEBFMCMF_01119 2.4e-228 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HEBFMCMF_01120 2.1e-247 yhfA C membrane
HEBFMCMF_01121 7.5e-17 1.15.1.2 C Rubrerythrin
HEBFMCMF_01122 1.1e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HEBFMCMF_01123 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HEBFMCMF_01124 6.3e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HEBFMCMF_01125 3.6e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HEBFMCMF_01126 1.7e-268 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HEBFMCMF_01127 5.4e-101 yhgD K Transcriptional regulator
HEBFMCMF_01128 1e-238 yhgE S YhgE Pip N-terminal domain protein
HEBFMCMF_01129 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HEBFMCMF_01130 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
HEBFMCMF_01131 1.6e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
HEBFMCMF_01132 1.4e-71 3.4.13.21 S ASCH
HEBFMCMF_01133 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEBFMCMF_01134 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HEBFMCMF_01135 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
HEBFMCMF_01136 2.9e-111 yhfK GM NmrA-like family
HEBFMCMF_01137 1.7e-298 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HEBFMCMF_01138 2.1e-64 yhfM
HEBFMCMF_01139 1.6e-241 yhfN 3.4.24.84 O Peptidase M48
HEBFMCMF_01140 1.4e-196 aprE 3.4.21.62 O Belongs to the peptidase S8 family
HEBFMCMF_01141 1.7e-78 VY92_01935 K acetyltransferase
HEBFMCMF_01142 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
HEBFMCMF_01143 4.3e-159 yfmC M Periplasmic binding protein
HEBFMCMF_01144 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HEBFMCMF_01145 2.5e-195 vraB 2.3.1.9 I Belongs to the thiolase family
HEBFMCMF_01146 8.6e-273 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HEBFMCMF_01147 5e-91 bioY S BioY family
HEBFMCMF_01148 2.8e-182 hemAT NT chemotaxis protein
HEBFMCMF_01149 1.6e-301 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
HEBFMCMF_01150 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEBFMCMF_01151 1.3e-32 yhzC S IDEAL
HEBFMCMF_01152 4.2e-109 comK K Competence transcription factor
HEBFMCMF_01153 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
HEBFMCMF_01154 8.1e-39 yhjA S Excalibur calcium-binding domain
HEBFMCMF_01155 1.4e-265 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEBFMCMF_01156 2e-26 yhjC S Protein of unknown function (DUF3311)
HEBFMCMF_01157 6.7e-60 yhjD
HEBFMCMF_01158 9.1e-110 yhjE S SNARE associated Golgi protein
HEBFMCMF_01159 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
HEBFMCMF_01160 3.4e-280 yhjG CH FAD binding domain
HEBFMCMF_01161 1.7e-93 yhjH K helix_turn_helix multiple antibiotic resistance protein
HEBFMCMF_01162 2.9e-213 glcP G Major Facilitator Superfamily
HEBFMCMF_01163 3.3e-197 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
HEBFMCMF_01164 9.9e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
HEBFMCMF_01165 3.1e-253 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
HEBFMCMF_01166 4.5e-188 yhjM 5.1.1.1 K Transcriptional regulator
HEBFMCMF_01167 4.2e-201 abrB S membrane
HEBFMCMF_01168 2.1e-211 EGP Transmembrane secretion effector
HEBFMCMF_01169 0.0 S Sugar transport-related sRNA regulator N-term
HEBFMCMF_01170 3.6e-25 yhjQ C COG1145 Ferredoxin
HEBFMCMF_01171 2.2e-78 yhjR S Rubrerythrin
HEBFMCMF_01172 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
HEBFMCMF_01173 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HEBFMCMF_01174 4.1e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HEBFMCMF_01175 0.0 sbcC L COG0419 ATPase involved in DNA repair
HEBFMCMF_01176 1.1e-49 yisB V COG1403 Restriction endonuclease
HEBFMCMF_01177 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
HEBFMCMF_01178 1.5e-65 gerPE S Spore germination protein GerPE
HEBFMCMF_01179 6.3e-24 gerPD S Spore germination protein
HEBFMCMF_01180 1.8e-54 gerPC S Spore germination protein
HEBFMCMF_01181 4e-34 gerPB S cell differentiation
HEBFMCMF_01182 1.9e-33 gerPA S Spore germination protein
HEBFMCMF_01183 1.5e-22 yisI S Spo0E like sporulation regulatory protein
HEBFMCMF_01184 1.1e-175 cotH M Spore Coat
HEBFMCMF_01185 7.1e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HEBFMCMF_01186 3e-57 yisL S UPF0344 protein
HEBFMCMF_01187 0.0 wprA O Belongs to the peptidase S8 family
HEBFMCMF_01188 3.4e-100 yisN S Protein of unknown function (DUF2777)
HEBFMCMF_01189 0.0 asnO 6.3.5.4 E Asparagine synthase
HEBFMCMF_01190 2.3e-87 yizA S Damage-inducible protein DinB
HEBFMCMF_01191 1.7e-148 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
HEBFMCMF_01192 4e-243 yisQ V Mate efflux family protein
HEBFMCMF_01193 1.7e-159 yisR K Transcriptional regulator
HEBFMCMF_01194 2.4e-184 purR K helix_turn _helix lactose operon repressor
HEBFMCMF_01195 7e-192 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
HEBFMCMF_01196 4.1e-92 yisT S DinB family
HEBFMCMF_01197 1.2e-106 argO S Lysine exporter protein LysE YggA
HEBFMCMF_01198 1.4e-278 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEBFMCMF_01199 3.4e-35 mcbG S Pentapeptide repeats (9 copies)
HEBFMCMF_01200 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HEBFMCMF_01201 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
HEBFMCMF_01202 2.7e-232 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HEBFMCMF_01203 1e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HEBFMCMF_01204 3.3e-121 comB 3.1.3.71 H Belongs to the ComB family
HEBFMCMF_01205 5.4e-141 yitD 4.4.1.19 S synthase
HEBFMCMF_01206 7.2e-113 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HEBFMCMF_01207 7.8e-221 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HEBFMCMF_01208 1.5e-228 yitG EGP Major facilitator Superfamily
HEBFMCMF_01209 5.3e-153 yitH K Acetyltransferase (GNAT) domain
HEBFMCMF_01210 5.1e-70 yjcF S Acetyltransferase (GNAT) domain
HEBFMCMF_01211 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HEBFMCMF_01212 3.3e-54 yajQ S Belongs to the UPF0234 family
HEBFMCMF_01213 6.9e-161 cvfB S protein conserved in bacteria
HEBFMCMF_01214 8.5e-94
HEBFMCMF_01215 1.4e-170
HEBFMCMF_01216 1.5e-97 S Sporulation delaying protein SdpA
HEBFMCMF_01217 1.5e-58 K Transcriptional regulator PadR-like family
HEBFMCMF_01218 6.6e-94
HEBFMCMF_01219 3.1e-44 yitR S Domain of unknown function (DUF3784)
HEBFMCMF_01220 1.9e-308 nprB 3.4.24.28 E Peptidase M4
HEBFMCMF_01221 9.3e-158 yitS S protein conserved in bacteria
HEBFMCMF_01222 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
HEBFMCMF_01223 5e-73 ipi S Intracellular proteinase inhibitor
HEBFMCMF_01224 1.2e-17 S Protein of unknown function (DUF3813)
HEBFMCMF_01226 4.6e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
HEBFMCMF_01227 1.4e-141 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HEBFMCMF_01228 6.2e-51 yitW S metal-sulfur cluster biosynthetic enzyme
HEBFMCMF_01229 1.5e-22 pilT S Proteolipid membrane potential modulator
HEBFMCMF_01230 1.7e-151 yitY C D-arabinono-1,4-lactone oxidase
HEBFMCMF_01231 1.4e-101 yitY C D-arabinono-1,4-lactone oxidase
HEBFMCMF_01232 1.2e-86 norB G Major Facilitator Superfamily
HEBFMCMF_01233 1.5e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HEBFMCMF_01234 2e-230 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HEBFMCMF_01235 1.6e-135 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HEBFMCMF_01236 1.6e-216 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HEBFMCMF_01237 3.3e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HEBFMCMF_01238 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
HEBFMCMF_01239 7.2e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HEBFMCMF_01240 9.5e-28 yjzC S YjzC-like protein
HEBFMCMF_01241 2.3e-16 yjzD S Protein of unknown function (DUF2929)
HEBFMCMF_01242 6.2e-142 yjaU I carboxylic ester hydrolase activity
HEBFMCMF_01243 1.2e-100 yjaV
HEBFMCMF_01244 2.5e-183 med S Transcriptional activator protein med
HEBFMCMF_01245 7.3e-26 comZ S ComZ
HEBFMCMF_01246 2.7e-22 yjzB
HEBFMCMF_01247 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HEBFMCMF_01248 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HEBFMCMF_01249 2.8e-148 yjaZ O Zn-dependent protease
HEBFMCMF_01250 1.8e-184 appD P Belongs to the ABC transporter superfamily
HEBFMCMF_01251 4.2e-186 appF E Belongs to the ABC transporter superfamily
HEBFMCMF_01252 7e-271 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
HEBFMCMF_01253 2.2e-168 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEBFMCMF_01254 3.9e-154 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEBFMCMF_01255 5e-147 yjbA S Belongs to the UPF0736 family
HEBFMCMF_01256 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HEBFMCMF_01257 0.0 oppA E ABC transporter substrate-binding protein
HEBFMCMF_01258 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEBFMCMF_01259 1e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEBFMCMF_01260 3.4e-197 oppD P Belongs to the ABC transporter superfamily
HEBFMCMF_01261 5.5e-172 oppF E Belongs to the ABC transporter superfamily
HEBFMCMF_01262 5.7e-212 yjbB EGP Major Facilitator Superfamily
HEBFMCMF_01263 6.9e-104 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEBFMCMF_01264 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HEBFMCMF_01265 1.3e-111 yjbE P Integral membrane protein TerC family
HEBFMCMF_01266 1.1e-113 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HEBFMCMF_01267 3.6e-221 yjbF S Competence protein
HEBFMCMF_01268 0.0 pepF E oligoendopeptidase F
HEBFMCMF_01269 1.8e-20
HEBFMCMF_01271 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HEBFMCMF_01272 3.7e-72 yjbI S Bacterial-like globin
HEBFMCMF_01273 3.2e-82 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HEBFMCMF_01274 4.1e-101 yjbK S protein conserved in bacteria
HEBFMCMF_01275 1.2e-61 yjbL S Belongs to the UPF0738 family
HEBFMCMF_01276 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
HEBFMCMF_01277 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HEBFMCMF_01278 3.4e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HEBFMCMF_01279 3e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HEBFMCMF_01280 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HEBFMCMF_01281 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HEBFMCMF_01282 4.9e-108 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
HEBFMCMF_01283 8.8e-217 thiO 1.4.3.19 E Glycine oxidase
HEBFMCMF_01284 2.6e-29 thiS H thiamine diphosphate biosynthetic process
HEBFMCMF_01285 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HEBFMCMF_01286 1.5e-186 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HEBFMCMF_01287 7.6e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HEBFMCMF_01288 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HEBFMCMF_01289 5.9e-54 yjbX S Spore coat protein
HEBFMCMF_01290 4.4e-82 cotZ S Spore coat protein
HEBFMCMF_01291 7.6e-96 cotY S Spore coat protein Z
HEBFMCMF_01292 1.2e-67 cotX S Spore Coat Protein X and V domain
HEBFMCMF_01293 7.4e-23 cotW
HEBFMCMF_01294 3.2e-49 cotV S Spore Coat Protein X and V domain
HEBFMCMF_01295 1.9e-56 yjcA S Protein of unknown function (DUF1360)
HEBFMCMF_01298 2.9e-38 spoVIF S Stage VI sporulation protein F
HEBFMCMF_01299 0.0 yjcD 3.6.4.12 L DNA helicase
HEBFMCMF_01300 1.7e-38
HEBFMCMF_01301 5.1e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEBFMCMF_01302 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
HEBFMCMF_01303 2.2e-136 yjcH P COG2382 Enterochelin esterase and related enzymes
HEBFMCMF_01305 5.5e-137 V COG1401 GTPase subunit of restriction endonuclease
HEBFMCMF_01306 2.9e-100
HEBFMCMF_01307 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HEBFMCMF_01308 5.5e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HEBFMCMF_01309 1.7e-96 rimJ 2.3.1.128 J Alanine acetyltransferase
HEBFMCMF_01310 3.6e-208 yjcL S Protein of unknown function (DUF819)
HEBFMCMF_01312 5.5e-176 L Belongs to the 'phage' integrase family
HEBFMCMF_01313 1.1e-39 S Helix-turn-helix domain
HEBFMCMF_01318 1.2e-21
HEBFMCMF_01320 7.7e-68
HEBFMCMF_01322 1.1e-110 L DNA-dependent DNA replication
HEBFMCMF_01323 2.1e-11 yodN
HEBFMCMF_01326 8.3e-143 dnaG 3.6.4.12 L DnaB-like helicase C terminal domain
HEBFMCMF_01327 5e-142 dnaG L Toprim-like
HEBFMCMF_01328 4.1e-11 K Cro/C1-type HTH DNA-binding domain
HEBFMCMF_01329 2.4e-61
HEBFMCMF_01331 7.9e-16
HEBFMCMF_01335 1.5e-45
HEBFMCMF_01336 4.8e-49
HEBFMCMF_01337 1.7e-12
HEBFMCMF_01339 2e-196 L DNA polymerase A domain
HEBFMCMF_01340 2.8e-167
HEBFMCMF_01342 1.4e-32 ruvC 3.1.22.4 L Crossover junction endodeoxyribonuclease RuvC
HEBFMCMF_01343 6.4e-15 S Protein of unknown function (DUF1523)
HEBFMCMF_01346 1.3e-39 nrdI 1.17.4.1 F Belongs to the NrdI family
HEBFMCMF_01347 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEBFMCMF_01349 3e-12
HEBFMCMF_01351 2.8e-153 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEBFMCMF_01353 4.3e-69 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F deoxyuridine 5'-triphosphate nucleotidohydrolase
HEBFMCMF_01354 7e-102 thyX 2.1.1.148 H Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant
HEBFMCMF_01355 5.9e-33 S protein conserved in bacteria
HEBFMCMF_01357 1.4e-28
HEBFMCMF_01358 2.1e-73 2.7.1.24 H dephospho-CoA kinase activity
HEBFMCMF_01359 2.8e-08
HEBFMCMF_01360 1.3e-42 K Sigma-70, region 4
HEBFMCMF_01361 8.2e-34
HEBFMCMF_01362 7.3e-12
HEBFMCMF_01363 8e-25 S Helix-turn-helix domain
HEBFMCMF_01364 1.6e-122 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
HEBFMCMF_01366 6.5e-24
HEBFMCMF_01367 5.9e-47
HEBFMCMF_01370 6.5e-113 3.2.1.15 M Right handed beta helix region
HEBFMCMF_01371 1.1e-56 S Pfam:DUF867
HEBFMCMF_01372 2.4e-28 K Cro/C1-type HTH DNA-binding domain
HEBFMCMF_01373 2.4e-43 M Glycosyltransferase like family 2
HEBFMCMF_01380 2.2e-79
HEBFMCMF_01383 4.2e-32 L HNH endonuclease
HEBFMCMF_01384 2.6e-44 L Phage terminase, small subunit
HEBFMCMF_01385 0.0 S Terminase
HEBFMCMF_01386 1.6e-225 S Phage portal protein
HEBFMCMF_01387 1.6e-121 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
HEBFMCMF_01388 1.6e-168 S Phage capsid family
HEBFMCMF_01389 2.3e-28 N domain, Protein
HEBFMCMF_01390 3.5e-25 S Phage gp6-like head-tail connector protein
HEBFMCMF_01391 2.9e-33 S Phage head-tail joining protein
HEBFMCMF_01393 2.2e-25
HEBFMCMF_01394 5.5e-72 N phage major tail protein, phi13 family
HEBFMCMF_01395 7.8e-31
HEBFMCMF_01396 2.6e-128 D Phage tail tape measure protein
HEBFMCMF_01397 3.9e-68 S Phage tail protein
HEBFMCMF_01398 6.6e-75 lyc 3.2.1.17 M Glycosyl hydrolases family 25
HEBFMCMF_01399 8.3e-42
HEBFMCMF_01402 8.8e-30 S Haemolysin XhlA
HEBFMCMF_01403 3.3e-148 xlyB 3.5.1.28 CBM50 MT N-acetylmuramoyl-L-alanine amidase
HEBFMCMF_01404 6.3e-33 S Bacteriophage A118-like holin, Hol118
HEBFMCMF_01406 1.2e-18 S YolD-like protein
HEBFMCMF_01407 4.8e-21 S protein disulfide oxidoreductase activity
HEBFMCMF_01409 2.3e-127 ftsK D FtsK/SpoIIIE family
HEBFMCMF_01410 2.6e-64
HEBFMCMF_01411 4.9e-11
HEBFMCMF_01412 1.3e-15 K Transcriptional regulator
HEBFMCMF_01413 3.8e-97 K Helix-turn-helix domain
HEBFMCMF_01415 2.1e-190 S Putative amidase domain
HEBFMCMF_01416 2.6e-44 yjcN
HEBFMCMF_01418 5.5e-80 L Transposase
HEBFMCMF_01420 9.4e-62 yqaS L DNA packaging
HEBFMCMF_01421 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
HEBFMCMF_01422 1.7e-139 IQ Enoyl-(Acyl carrier protein) reductase
HEBFMCMF_01424 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
HEBFMCMF_01425 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
HEBFMCMF_01426 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
HEBFMCMF_01427 4.1e-50 yjdF S Protein of unknown function (DUF2992)
HEBFMCMF_01428 2.2e-90 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
HEBFMCMF_01430 1.2e-80 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HEBFMCMF_01431 1.6e-28 S Domain of unknown function (DUF4177)
HEBFMCMF_01432 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
HEBFMCMF_01433 1.6e-174 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HEBFMCMF_01435 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
HEBFMCMF_01436 1.8e-81 S Protein of unknown function (DUF2690)
HEBFMCMF_01437 8.9e-20 yjfB S Putative motility protein
HEBFMCMF_01438 1.2e-168 yjfC O Predicted Zn-dependent protease (DUF2268)
HEBFMCMF_01439 6e-45 T PhoQ Sensor
HEBFMCMF_01440 2e-103 yjgB S Domain of unknown function (DUF4309)
HEBFMCMF_01441 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HEBFMCMF_01442 4.3e-95 yjgD S Protein of unknown function (DUF1641)
HEBFMCMF_01443 6.6e-07 S Domain of unknown function (DUF4352)
HEBFMCMF_01444 3.8e-116 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
HEBFMCMF_01446 8.9e-223 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
HEBFMCMF_01447 3.8e-218 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HEBFMCMF_01448 8.2e-30
HEBFMCMF_01449 1.1e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HEBFMCMF_01450 1.9e-122 ybbM S transport system, permease component
HEBFMCMF_01451 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
HEBFMCMF_01452 5.1e-176 yjlA EG Putative multidrug resistance efflux transporter
HEBFMCMF_01453 3.7e-90 yjlB S Cupin domain
HEBFMCMF_01454 7.1e-66 yjlC S Protein of unknown function (DUF1641)
HEBFMCMF_01455 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
HEBFMCMF_01456 2.7e-279 uxaC 5.3.1.12 G glucuronate isomerase
HEBFMCMF_01457 7.1e-248 yjmB G symporter YjmB
HEBFMCMF_01458 9.3e-189 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HEBFMCMF_01459 1.1e-189 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
HEBFMCMF_01460 1.4e-214 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HEBFMCMF_01461 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HEBFMCMF_01462 1.6e-225 exuT G Sugar (and other) transporter
HEBFMCMF_01463 5.2e-184 exuR K transcriptional
HEBFMCMF_01464 8.6e-281 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
HEBFMCMF_01465 3.3e-283 uxaA 4.2.1.7, 4.4.1.24 G Altronate
HEBFMCMF_01466 4.3e-130 MA20_18170 S membrane transporter protein
HEBFMCMF_01467 3.1e-78 yjoA S DinB family
HEBFMCMF_01468 2.7e-246 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
HEBFMCMF_01469 1e-212 S response regulator aspartate phosphatase
HEBFMCMF_01471 6.3e-41 S YCII-related domain
HEBFMCMF_01472 1.9e-167 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
HEBFMCMF_01473 6.1e-61 yjqA S Bacterial PH domain
HEBFMCMF_01474 2.1e-111 yjqB S Pfam:DUF867
HEBFMCMF_01475 4.4e-160 ydbD P Catalase
HEBFMCMF_01476 3.9e-110 xkdA E IrrE N-terminal-like domain
HEBFMCMF_01477 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
HEBFMCMF_01479 5.9e-157 xkdB K sequence-specific DNA binding
HEBFMCMF_01480 4.1e-118 xkdC L Bacterial dnaA protein
HEBFMCMF_01483 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
HEBFMCMF_01484 6.3e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HEBFMCMF_01485 4.1e-139 xtmA L phage terminase small subunit
HEBFMCMF_01486 9e-253 xtmB S phage terminase, large subunit
HEBFMCMF_01487 4.6e-285 yqbA S portal protein
HEBFMCMF_01488 3.2e-131 yqbD 2.1.1.72 L Putative phage serine protease XkdF
HEBFMCMF_01489 5.8e-169 xkdG S Phage capsid family
HEBFMCMF_01490 4.8e-61 yqbG S Protein of unknown function (DUF3199)
HEBFMCMF_01491 8.7e-65 yqbH S Domain of unknown function (DUF3599)
HEBFMCMF_01492 1.4e-86 xkdI S Bacteriophage HK97-gp10, putative tail-component
HEBFMCMF_01493 6e-76 xkdJ
HEBFMCMF_01494 2.5e-256 xkdK S Phage tail sheath C-terminal domain
HEBFMCMF_01495 6.1e-76 xkdM S Phage tail tube protein
HEBFMCMF_01496 1e-75 S Phage XkdN-like tail assembly chaperone protein, TAC
HEBFMCMF_01497 3.7e-264 xkdO L Transglycosylase SLT domain
HEBFMCMF_01498 3.9e-117 xkdP S Lysin motif
HEBFMCMF_01499 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
HEBFMCMF_01500 2.1e-39 xkdR S Protein of unknown function (DUF2577)
HEBFMCMF_01501 5.3e-69 xkdS S Protein of unknown function (DUF2634)
HEBFMCMF_01502 6.7e-190 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HEBFMCMF_01503 3.4e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HEBFMCMF_01504 6.7e-41
HEBFMCMF_01505 9e-178
HEBFMCMF_01506 7.7e-44 xkdW S XkdW protein
HEBFMCMF_01507 4.2e-22 xkdX
HEBFMCMF_01508 1.4e-150 xepA
HEBFMCMF_01509 6.2e-39 xhlA S Haemolysin XhlA
HEBFMCMF_01510 9.3e-40 xhlB S SPP1 phage holin
HEBFMCMF_01511 1.3e-162 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HEBFMCMF_01512 6.7e-23 spoIISB S Stage II sporulation protein SB
HEBFMCMF_01513 5.2e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
HEBFMCMF_01514 5.8e-175 pit P phosphate transporter
HEBFMCMF_01515 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
HEBFMCMF_01516 1.2e-239 steT E amino acid
HEBFMCMF_01517 4.6e-182 mhqA E COG0346 Lactoylglutathione lyase and related lyases
HEBFMCMF_01518 7.7e-11 mhqA E COG0346 Lactoylglutathione lyase and related lyases
HEBFMCMF_01519 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HEBFMCMF_01520 3.2e-178 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HEBFMCMF_01522 2.6e-210 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEBFMCMF_01523 1.1e-134 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
HEBFMCMF_01524 5.1e-153 dppA E D-aminopeptidase
HEBFMCMF_01525 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEBFMCMF_01526 4.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEBFMCMF_01527 1.3e-187 dppD P Belongs to the ABC transporter superfamily
HEBFMCMF_01528 0.0 dppE E ABC transporter substrate-binding protein
HEBFMCMF_01530 4.5e-177 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HEBFMCMF_01531 4.4e-200 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HEBFMCMF_01532 3.1e-164 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HEBFMCMF_01533 7.2e-186 ykfD E Belongs to the ABC transporter superfamily
HEBFMCMF_01534 3.1e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
HEBFMCMF_01535 1.2e-160 ykgA E Amidinotransferase
HEBFMCMF_01536 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
HEBFMCMF_01537 3e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HEBFMCMF_01538 7.2e-09
HEBFMCMF_01539 2.3e-128 ykjA S Protein of unknown function (DUF421)
HEBFMCMF_01540 1e-98 ykkA S Protein of unknown function (DUF664)
HEBFMCMF_01541 1.7e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HEBFMCMF_01542 3.5e-55 ykkC P Multidrug resistance protein
HEBFMCMF_01543 7e-50 ykkD P Multidrug resistance protein
HEBFMCMF_01544 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HEBFMCMF_01545 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HEBFMCMF_01546 8.1e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HEBFMCMF_01547 1.3e-70 ohrA O Organic hydroperoxide resistance protein
HEBFMCMF_01548 4.8e-73 ohrR K COG1846 Transcriptional regulators
HEBFMCMF_01549 8.4e-72 ohrB O Organic hydroperoxide resistance protein
HEBFMCMF_01551 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
HEBFMCMF_01552 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HEBFMCMF_01553 5e-176 isp O Belongs to the peptidase S8 family
HEBFMCMF_01554 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HEBFMCMF_01555 5.3e-136 ykoC P Cobalt transport protein
HEBFMCMF_01556 4.4e-305 P ABC transporter, ATP-binding protein
HEBFMCMF_01557 3.3e-77 ykoE S ABC-type cobalt transport system, permease component
HEBFMCMF_01558 1.8e-110 ykoF S YKOF-related Family
HEBFMCMF_01559 2.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEBFMCMF_01560 6.3e-241 ykoH 2.7.13.3 T Histidine kinase
HEBFMCMF_01561 1.4e-111 ykoI S Peptidase propeptide and YPEB domain
HEBFMCMF_01562 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
HEBFMCMF_01565 2.2e-222 mgtE P Acts as a magnesium transporter
HEBFMCMF_01566 1.4e-53 tnrA K transcriptional
HEBFMCMF_01567 1.3e-17
HEBFMCMF_01568 3.4e-25 ykoL
HEBFMCMF_01569 1.3e-81 mhqR K transcriptional
HEBFMCMF_01570 3.4e-213 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HEBFMCMF_01571 1.1e-98 ykoP G polysaccharide deacetylase
HEBFMCMF_01572 7.1e-155 ykoQ S Calcineurin-like phosphoesterase superfamily domain
HEBFMCMF_01573 0.0 ykoS
HEBFMCMF_01574 2.1e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HEBFMCMF_01575 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
HEBFMCMF_01576 3.2e-161 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HEBFMCMF_01577 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
HEBFMCMF_01578 3.5e-109 ykoX S membrane-associated protein
HEBFMCMF_01579 6e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HEBFMCMF_01580 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEBFMCMF_01581 1.2e-112 rsgI S Anti-sigma factor N-terminus
HEBFMCMF_01582 1.9e-26 sspD S small acid-soluble spore protein
HEBFMCMF_01583 1.9e-124 ykrK S Domain of unknown function (DUF1836)
HEBFMCMF_01584 3.5e-155 htpX O Belongs to the peptidase M48B family
HEBFMCMF_01585 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
HEBFMCMF_01586 1.2e-10 ydfR S Protein of unknown function (DUF421)
HEBFMCMF_01587 1.4e-18 ykzE
HEBFMCMF_01588 1.4e-189 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
HEBFMCMF_01589 0.0 kinE 2.7.13.3 T Histidine kinase
HEBFMCMF_01590 3.5e-88 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HEBFMCMF_01592 2.8e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HEBFMCMF_01593 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HEBFMCMF_01594 4.2e-149 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HEBFMCMF_01595 1.1e-231 mtnE 2.6.1.83 E Aminotransferase
HEBFMCMF_01596 3.4e-230 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HEBFMCMF_01597 8.3e-136 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HEBFMCMF_01598 6.1e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HEBFMCMF_01599 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HEBFMCMF_01600 4.9e-51 XK27_09985 S Protein of unknown function (DUF1232)
HEBFMCMF_01601 6.4e-09 S Spo0E like sporulation regulatory protein
HEBFMCMF_01602 1.4e-64 eag
HEBFMCMF_01603 1.6e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
HEBFMCMF_01604 1.3e-75 ykvE K transcriptional
HEBFMCMF_01605 2.5e-125 motB N Flagellar motor protein
HEBFMCMF_01606 1e-137 motA N flagellar motor
HEBFMCMF_01607 0.0 clpE O Belongs to the ClpA ClpB family
HEBFMCMF_01608 1.8e-179 ykvI S membrane
HEBFMCMF_01609 7.3e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HEBFMCMF_01610 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
HEBFMCMF_01611 6.4e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HEBFMCMF_01612 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HEBFMCMF_01613 2e-61 ykvN K Transcriptional regulator
HEBFMCMF_01614 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
HEBFMCMF_01615 6.4e-215 ykvP 3.5.1.28 M Glycosyl transferases group 1
HEBFMCMF_01616 4.6e-35 3.5.1.104 M LysM domain
HEBFMCMF_01617 1.1e-162 G Glycosyl hydrolases family 18
HEBFMCMF_01618 2.8e-45 ykvR S Protein of unknown function (DUF3219)
HEBFMCMF_01619 6e-25 ykvS S protein conserved in bacteria
HEBFMCMF_01620 2.8e-28
HEBFMCMF_01621 3.1e-102 ykvT 3.5.1.28 M Cell Wall Hydrolase
HEBFMCMF_01622 2.9e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEBFMCMF_01623 4.9e-90 stoA CO thiol-disulfide
HEBFMCMF_01624 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HEBFMCMF_01625 2.3e-09
HEBFMCMF_01626 6.3e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HEBFMCMF_01627 9.8e-180 ykvZ 5.1.1.1 K Transcriptional regulator
HEBFMCMF_01629 7.6e-128 glcT K antiterminator
HEBFMCMF_01630 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HEBFMCMF_01631 2.1e-39 ptsH G phosphocarrier protein HPr
HEBFMCMF_01632 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HEBFMCMF_01633 7.2e-39 splA S Transcriptional regulator
HEBFMCMF_01634 1.3e-201 splB 4.1.99.14 L Spore photoproduct lyase
HEBFMCMF_01635 5.9e-126 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEBFMCMF_01636 3.2e-262 mcpC NT chemotaxis protein
HEBFMCMF_01637 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HEBFMCMF_01638 8e-124 ykwD J protein with SCP PR1 domains
HEBFMCMF_01639 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
HEBFMCMF_01640 0.0 pilS 2.7.13.3 T Histidine kinase
HEBFMCMF_01641 1.8e-220 patA 2.6.1.1 E Aminotransferase
HEBFMCMF_01642 2.2e-15
HEBFMCMF_01643 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
HEBFMCMF_01644 1.7e-84 ykyB S YkyB-like protein
HEBFMCMF_01645 9.9e-236 ykuC EGP Major facilitator Superfamily
HEBFMCMF_01646 3.9e-87 ykuD S protein conserved in bacteria
HEBFMCMF_01647 9.4e-166 ykuE S Metallophosphoesterase
HEBFMCMF_01648 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEBFMCMF_01649 0.0 3.2.1.132 M Putative peptidoglycan binding domain
HEBFMCMF_01651 5.2e-234 ykuI T Diguanylate phosphodiesterase
HEBFMCMF_01652 3.9e-37 ykuJ S protein conserved in bacteria
HEBFMCMF_01653 4.4e-94 ykuK S Ribonuclease H-like
HEBFMCMF_01654 3.9e-27 ykzF S Antirepressor AbbA
HEBFMCMF_01655 1.6e-76 ykuL S CBS domain
HEBFMCMF_01656 3.5e-168 ccpC K Transcriptional regulator
HEBFMCMF_01657 2.4e-86 fld C Flavodoxin domain
HEBFMCMF_01658 4.8e-173 ykuO
HEBFMCMF_01659 1.1e-77 fld C Flavodoxin
HEBFMCMF_01660 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HEBFMCMF_01661 2.1e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HEBFMCMF_01662 9e-37 ykuS S Belongs to the UPF0180 family
HEBFMCMF_01663 8.8e-142 ykuT M Mechanosensitive ion channel
HEBFMCMF_01664 3.9e-101 ykuU O Alkyl hydroperoxide reductase
HEBFMCMF_01665 6.3e-81 ykuV CO thiol-disulfide
HEBFMCMF_01666 5.8e-95 rok K Repressor of ComK
HEBFMCMF_01667 3.2e-146 yknT
HEBFMCMF_01668 1.6e-108 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HEBFMCMF_01669 2.9e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HEBFMCMF_01670 5.8e-244 moeA 2.10.1.1 H molybdopterin
HEBFMCMF_01671 4.6e-91 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HEBFMCMF_01672 9.4e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
HEBFMCMF_01673 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HEBFMCMF_01674 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
HEBFMCMF_01675 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
HEBFMCMF_01676 2.9e-117 yknW S Yip1 domain
HEBFMCMF_01677 3.3e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HEBFMCMF_01678 2.5e-124 macB V ABC transporter, ATP-binding protein
HEBFMCMF_01679 2.1e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
HEBFMCMF_01680 3.1e-136 fruR K Transcriptional regulator
HEBFMCMF_01681 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
HEBFMCMF_01682 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HEBFMCMF_01683 1.4e-104 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HEBFMCMF_01684 8.1e-39 ykoA
HEBFMCMF_01685 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HEBFMCMF_01686 4e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HEBFMCMF_01687 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HEBFMCMF_01688 1.1e-12 S Uncharacterized protein YkpC
HEBFMCMF_01689 7.7e-183 mreB D Rod-share determining protein MreBH
HEBFMCMF_01690 1.5e-43 abrB K of stationary sporulation gene expression
HEBFMCMF_01691 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
HEBFMCMF_01692 1.5e-160 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
HEBFMCMF_01693 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
HEBFMCMF_01694 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HEBFMCMF_01695 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEBFMCMF_01696 8.2e-31 ykzG S Belongs to the UPF0356 family
HEBFMCMF_01697 5.5e-147 ykrA S hydrolases of the HAD superfamily
HEBFMCMF_01698 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HEBFMCMF_01700 1.1e-100 recN L Putative cell-wall binding lipoprotein
HEBFMCMF_01701 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HEBFMCMF_01702 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HEBFMCMF_01703 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HEBFMCMF_01704 1.6e-242 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HEBFMCMF_01705 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
HEBFMCMF_01706 3.5e-277 speA 4.1.1.19 E Arginine
HEBFMCMF_01707 1.6e-42 yktA S Belongs to the UPF0223 family
HEBFMCMF_01708 2.1e-117 yktB S Belongs to the UPF0637 family
HEBFMCMF_01709 7.1e-26 ykzI
HEBFMCMF_01710 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
HEBFMCMF_01711 2.2e-76 ykzC S Acetyltransferase (GNAT) family
HEBFMCMF_01712 8.7e-170 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HEBFMCMF_01713 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
HEBFMCMF_01714 0.0 ylaA
HEBFMCMF_01715 2.7e-42 ylaB
HEBFMCMF_01716 2.5e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
HEBFMCMF_01717 7.1e-12 sigC S Putative zinc-finger
HEBFMCMF_01718 4.1e-38 ylaE
HEBFMCMF_01719 8.2e-22 S Family of unknown function (DUF5325)
HEBFMCMF_01720 0.0 typA T GTP-binding protein TypA
HEBFMCMF_01721 4.2e-47 ylaH S YlaH-like protein
HEBFMCMF_01722 2.5e-32 ylaI S protein conserved in bacteria
HEBFMCMF_01723 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HEBFMCMF_01724 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
HEBFMCMF_01725 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HEBFMCMF_01726 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
HEBFMCMF_01727 8.7e-44 ylaN S Belongs to the UPF0358 family
HEBFMCMF_01728 1.9e-212 ftsW D Belongs to the SEDS family
HEBFMCMF_01729 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HEBFMCMF_01730 1.9e-164 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HEBFMCMF_01731 4.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HEBFMCMF_01732 5.8e-189 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HEBFMCMF_01733 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HEBFMCMF_01734 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HEBFMCMF_01735 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HEBFMCMF_01736 8.8e-167 ctaG S cytochrome c oxidase
HEBFMCMF_01737 7e-62 ylbA S YugN-like family
HEBFMCMF_01738 2.6e-74 ylbB T COG0517 FOG CBS domain
HEBFMCMF_01739 4.3e-200 ylbC S protein with SCP PR1 domains
HEBFMCMF_01740 4.1e-63 ylbD S Putative coat protein
HEBFMCMF_01741 6.7e-37 ylbE S YlbE-like protein
HEBFMCMF_01742 6.8e-75 ylbF S Belongs to the UPF0342 family
HEBFMCMF_01743 3.7e-38 ylbG S UPF0298 protein
HEBFMCMF_01744 4.6e-97 rsmD 2.1.1.171 L Methyltransferase
HEBFMCMF_01745 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HEBFMCMF_01746 1.1e-220 ylbJ S Sporulation integral membrane protein YlbJ
HEBFMCMF_01747 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
HEBFMCMF_01748 4.4e-186 ylbL T Belongs to the peptidase S16 family
HEBFMCMF_01749 4e-234 ylbM S Belongs to the UPF0348 family
HEBFMCMF_01751 8.7e-90 yceD S metal-binding, possibly nucleic acid-binding protein
HEBFMCMF_01752 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HEBFMCMF_01753 1.3e-73 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HEBFMCMF_01754 1.5e-88 ylbP K n-acetyltransferase
HEBFMCMF_01755 4e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HEBFMCMF_01756 6e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HEBFMCMF_01757 2.9e-78 mraZ K Belongs to the MraZ family
HEBFMCMF_01758 7.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HEBFMCMF_01759 3.7e-44 ftsL D Essential cell division protein
HEBFMCMF_01760 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HEBFMCMF_01761 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
HEBFMCMF_01762 1.2e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HEBFMCMF_01763 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HEBFMCMF_01764 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HEBFMCMF_01765 5.7e-186 spoVE D Belongs to the SEDS family
HEBFMCMF_01766 4.3e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HEBFMCMF_01767 5.3e-167 murB 1.3.1.98 M cell wall formation
HEBFMCMF_01768 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HEBFMCMF_01769 4.1e-103 ylxW S protein conserved in bacteria
HEBFMCMF_01770 1.8e-91 ylxX S protein conserved in bacteria
HEBFMCMF_01771 6.2e-58 sbp S small basic protein
HEBFMCMF_01772 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HEBFMCMF_01773 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HEBFMCMF_01774 0.0 bpr O COG1404 Subtilisin-like serine proteases
HEBFMCMF_01775 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HEBFMCMF_01776 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEBFMCMF_01777 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEBFMCMF_01778 3.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HEBFMCMF_01779 2.3e-253 argE 3.5.1.16 E Acetylornithine deacetylase
HEBFMCMF_01780 9e-37 ylmC S sporulation protein
HEBFMCMF_01781 5.9e-157 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
HEBFMCMF_01782 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HEBFMCMF_01783 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HEBFMCMF_01784 1.6e-39 yggT S membrane
HEBFMCMF_01785 7.5e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
HEBFMCMF_01786 2.6e-67 divIVA D Cell division initiation protein
HEBFMCMF_01787 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HEBFMCMF_01788 8.5e-63 dksA T COG1734 DnaK suppressor protein
HEBFMCMF_01789 2e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HEBFMCMF_01790 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HEBFMCMF_01791 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HEBFMCMF_01792 2.2e-230 pyrP F Xanthine uracil
HEBFMCMF_01793 2.9e-165 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HEBFMCMF_01794 2e-249 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HEBFMCMF_01795 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HEBFMCMF_01796 0.0 carB 6.3.5.5 F Belongs to the CarB family
HEBFMCMF_01797 1.4e-144 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HEBFMCMF_01798 1.4e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HEBFMCMF_01799 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HEBFMCMF_01800 1.2e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HEBFMCMF_01802 1.7e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HEBFMCMF_01803 3.2e-179 cysP P phosphate transporter
HEBFMCMF_01804 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HEBFMCMF_01805 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
HEBFMCMF_01806 2.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HEBFMCMF_01807 2.2e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
HEBFMCMF_01808 4.3e-83 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
HEBFMCMF_01809 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HEBFMCMF_01810 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
HEBFMCMF_01811 3.1e-156 yloC S stress-induced protein
HEBFMCMF_01812 1.5e-40 ylzA S Belongs to the UPF0296 family
HEBFMCMF_01813 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HEBFMCMF_01814 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HEBFMCMF_01815 8.2e-224 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HEBFMCMF_01816 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HEBFMCMF_01817 5.1e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HEBFMCMF_01818 3.8e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HEBFMCMF_01819 8.4e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HEBFMCMF_01820 1.4e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HEBFMCMF_01821 1.6e-140 stp 3.1.3.16 T phosphatase
HEBFMCMF_01822 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HEBFMCMF_01823 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HEBFMCMF_01824 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HEBFMCMF_01825 6.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
HEBFMCMF_01826 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HEBFMCMF_01827 5.5e-59 asp S protein conserved in bacteria
HEBFMCMF_01828 1.3e-299 yloV S kinase related to dihydroxyacetone kinase
HEBFMCMF_01829 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
HEBFMCMF_01830 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
HEBFMCMF_01831 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HEBFMCMF_01832 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HEBFMCMF_01833 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HEBFMCMF_01834 9.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HEBFMCMF_01835 6.1e-129 IQ reductase
HEBFMCMF_01836 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEBFMCMF_01837 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HEBFMCMF_01838 0.0 smc D Required for chromosome condensation and partitioning
HEBFMCMF_01839 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HEBFMCMF_01840 2.9e-87
HEBFMCMF_01841 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HEBFMCMF_01842 1e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HEBFMCMF_01843 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HEBFMCMF_01844 4.5e-36 ylqC S Belongs to the UPF0109 family
HEBFMCMF_01845 7e-60 ylqD S YlqD protein
HEBFMCMF_01846 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HEBFMCMF_01847 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HEBFMCMF_01848 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HEBFMCMF_01849 4.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HEBFMCMF_01850 1e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEBFMCMF_01851 4.6e-289 ylqG
HEBFMCMF_01852 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
HEBFMCMF_01853 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HEBFMCMF_01854 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HEBFMCMF_01855 1.7e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
HEBFMCMF_01856 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HEBFMCMF_01857 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HEBFMCMF_01858 2.5e-169 xerC L tyrosine recombinase XerC
HEBFMCMF_01859 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HEBFMCMF_01860 1.3e-249 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HEBFMCMF_01861 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HEBFMCMF_01862 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HEBFMCMF_01863 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
HEBFMCMF_01864 1.9e-31 fliE N Flagellar hook-basal body
HEBFMCMF_01865 2.4e-255 fliF N The M ring may be actively involved in energy transduction
HEBFMCMF_01866 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HEBFMCMF_01867 3.3e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
HEBFMCMF_01868 4e-240 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HEBFMCMF_01869 1.5e-69 fliJ N Flagellar biosynthesis chaperone
HEBFMCMF_01870 7.7e-37 ylxF S MgtE intracellular N domain
HEBFMCMF_01871 8.6e-220 fliK N Flagellar hook-length control protein
HEBFMCMF_01872 1.7e-72 flgD N Flagellar basal body rod modification protein
HEBFMCMF_01873 8.2e-140 flgG N Flagellar basal body rod
HEBFMCMF_01874 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
HEBFMCMF_01875 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HEBFMCMF_01876 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HEBFMCMF_01877 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
HEBFMCMF_01878 2.1e-96 fliZ N Flagellar biosynthesis protein, FliO
HEBFMCMF_01879 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
HEBFMCMF_01880 2.2e-36 fliQ N Role in flagellar biosynthesis
HEBFMCMF_01881 3.6e-132 fliR N Flagellar biosynthetic protein FliR
HEBFMCMF_01882 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HEBFMCMF_01883 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HEBFMCMF_01884 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
HEBFMCMF_01885 7.5e-158 flhG D Belongs to the ParA family
HEBFMCMF_01886 2.9e-196 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HEBFMCMF_01887 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
HEBFMCMF_01888 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
HEBFMCMF_01889 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HEBFMCMF_01890 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HEBFMCMF_01891 9.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEBFMCMF_01892 3.1e-76 ylxL
HEBFMCMF_01893 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
HEBFMCMF_01894 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HEBFMCMF_01895 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HEBFMCMF_01896 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HEBFMCMF_01897 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HEBFMCMF_01898 7.7e-138 cdsA 2.7.7.41 S Belongs to the CDS family
HEBFMCMF_01899 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HEBFMCMF_01900 7.7e-233 rasP M zinc metalloprotease
HEBFMCMF_01901 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HEBFMCMF_01902 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEBFMCMF_01903 2.1e-79 rimP S Required for maturation of 30S ribosomal subunits
HEBFMCMF_01904 1.1e-203 nusA K Participates in both transcription termination and antitermination
HEBFMCMF_01905 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
HEBFMCMF_01906 3.1e-47 ylxQ J ribosomal protein
HEBFMCMF_01907 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HEBFMCMF_01908 3.9e-44 ylxP S protein conserved in bacteria
HEBFMCMF_01909 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HEBFMCMF_01910 1.5e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HEBFMCMF_01911 2.3e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HEBFMCMF_01912 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HEBFMCMF_01913 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HEBFMCMF_01914 4e-181 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
HEBFMCMF_01915 1.3e-232 pepR S Belongs to the peptidase M16 family
HEBFMCMF_01916 2.6e-42 ymxH S YlmC YmxH family
HEBFMCMF_01917 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
HEBFMCMF_01918 2.2e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HEBFMCMF_01919 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HEBFMCMF_01920 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HEBFMCMF_01921 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HEBFMCMF_01922 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEBFMCMF_01923 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
HEBFMCMF_01924 4.4e-32 S YlzJ-like protein
HEBFMCMF_01925 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HEBFMCMF_01926 1.4e-133 ymfC K Transcriptional regulator
HEBFMCMF_01927 3.8e-205 ymfD EGP Major facilitator Superfamily
HEBFMCMF_01928 3e-232 ymfF S Peptidase M16
HEBFMCMF_01929 2.3e-240 ymfH S zinc protease
HEBFMCMF_01930 9.2e-130 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HEBFMCMF_01931 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
HEBFMCMF_01932 2.7e-143 ymfK S Protein of unknown function (DUF3388)
HEBFMCMF_01933 1.2e-123 ymfM S protein conserved in bacteria
HEBFMCMF_01934 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HEBFMCMF_01935 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
HEBFMCMF_01936 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HEBFMCMF_01937 1.3e-213 pbpX V Beta-lactamase
HEBFMCMF_01938 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
HEBFMCMF_01939 1.9e-152 ymdB S protein conserved in bacteria
HEBFMCMF_01940 1.2e-36 spoVS S Stage V sporulation protein S
HEBFMCMF_01941 1.9e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HEBFMCMF_01942 3e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HEBFMCMF_01943 1.7e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HEBFMCMF_01944 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HEBFMCMF_01945 2.2e-88 cotE S Spore coat protein
HEBFMCMF_01946 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HEBFMCMF_01947 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HEBFMCMF_01948 8.9e-70 S Regulatory protein YrvL
HEBFMCMF_01949 1.2e-97 ymcC S Membrane
HEBFMCMF_01950 4.4e-109 pksA K Transcriptional regulator
HEBFMCMF_01951 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
HEBFMCMF_01952 6.4e-162 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HEBFMCMF_01954 7.8e-185 pksD Q Acyl transferase domain
HEBFMCMF_01955 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HEBFMCMF_01956 1.4e-37 acpK IQ Phosphopantetheine attachment site
HEBFMCMF_01957 9.6e-236 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HEBFMCMF_01958 7.4e-244 pksG 2.3.3.10 I synthase
HEBFMCMF_01959 2.5e-141 pksH 4.2.1.18 I enoyl-CoA hydratase
HEBFMCMF_01960 5.7e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
HEBFMCMF_01961 0.0 rhiB IQ polyketide synthase
HEBFMCMF_01962 0.0 pfaA Q Polyketide synthase of type I
HEBFMCMF_01963 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
HEBFMCMF_01964 0.0 dhbF IQ polyketide synthase
HEBFMCMF_01965 0.0 pks13 HQ Beta-ketoacyl synthase
HEBFMCMF_01966 2.2e-232 cypA C Cytochrome P450
HEBFMCMF_01967 4.4e-61 ymzB
HEBFMCMF_01968 8.1e-162 ymaE S Metallo-beta-lactamase superfamily
HEBFMCMF_01969 1.5e-250 aprX O Belongs to the peptidase S8 family
HEBFMCMF_01970 1.9e-07 K Transcriptional regulator
HEBFMCMF_01971 2.1e-126 ymaC S Replication protein
HEBFMCMF_01972 1e-78 ymaD O redox protein, regulator of disulfide bond formation
HEBFMCMF_01973 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
HEBFMCMF_01974 4.9e-51 ebrA P Small Multidrug Resistance protein
HEBFMCMF_01976 2.1e-46 ymaF S YmaF family
HEBFMCMF_01977 7.9e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HEBFMCMF_01978 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HEBFMCMF_01979 8.2e-23
HEBFMCMF_01980 4.5e-22 ymzA
HEBFMCMF_01981 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HEBFMCMF_01982 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEBFMCMF_01983 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEBFMCMF_01984 2e-109 ymaB
HEBFMCMF_01985 5.7e-114 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HEBFMCMF_01986 1.7e-176 spoVK O stage V sporulation protein K
HEBFMCMF_01987 1.6e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HEBFMCMF_01988 3.3e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HEBFMCMF_01989 4.3e-68 glnR K transcriptional
HEBFMCMF_01990 3.5e-260 glnA 6.3.1.2 E glutamine synthetase
HEBFMCMF_01991 5e-10
HEBFMCMF_01993 2.1e-36
HEBFMCMF_01994 3.4e-89 G SMI1-KNR4 cell-wall
HEBFMCMF_01995 4.3e-19 ynaC
HEBFMCMF_01996 1.5e-97 ynaD J Acetyltransferase (GNAT) domain
HEBFMCMF_01998 2.6e-73 S CAAX protease self-immunity
HEBFMCMF_02000 5.5e-20 K Cro/C1-type HTH DNA-binding domain
HEBFMCMF_02001 3.5e-109 ynaE S Domain of unknown function (DUF3885)
HEBFMCMF_02004 4.6e-82 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
HEBFMCMF_02005 9.6e-253 xynT G MFS/sugar transport protein
HEBFMCMF_02006 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HEBFMCMF_02007 8.1e-213 xylR GK ROK family
HEBFMCMF_02008 6.4e-262 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HEBFMCMF_02009 1.6e-290 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
HEBFMCMF_02010 3.7e-111 yokF 3.1.31.1 L RNA catabolic process
HEBFMCMF_02011 6.1e-255 iolT EGP Major facilitator Superfamily
HEBFMCMF_02012 1e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HEBFMCMF_02013 4.5e-82 yncE S Protein of unknown function (DUF2691)
HEBFMCMF_02014 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HEBFMCMF_02015 8.9e-15
HEBFMCMF_02018 2.1e-162 S Thymidylate synthase
HEBFMCMF_02020 3.2e-133 S Domain of unknown function, YrpD
HEBFMCMF_02023 7.9e-25 tatA U protein secretion
HEBFMCMF_02024 1.8e-71
HEBFMCMF_02025 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
HEBFMCMF_02028 5.3e-284 gerAA EG Spore germination protein
HEBFMCMF_02029 5e-196 gerAB U Spore germination
HEBFMCMF_02030 4.2e-220 gerLC S Spore germination protein
HEBFMCMF_02031 2.9e-153 yndG S DoxX-like family
HEBFMCMF_02032 3.2e-115 yndH S Domain of unknown function (DUF4166)
HEBFMCMF_02033 0.0 yndJ S YndJ-like protein
HEBFMCMF_02035 9.6e-138 yndL S Replication protein
HEBFMCMF_02036 6.4e-73 yndM S Protein of unknown function (DUF2512)
HEBFMCMF_02037 2.4e-74 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HEBFMCMF_02038 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HEBFMCMF_02039 9.9e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HEBFMCMF_02040 6.6e-111 yneB L resolvase
HEBFMCMF_02041 1.3e-32 ynzC S UPF0291 protein
HEBFMCMF_02042 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HEBFMCMF_02043 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
HEBFMCMF_02044 1.8e-28 yneF S UPF0154 protein
HEBFMCMF_02045 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
HEBFMCMF_02046 2.1e-126 ccdA O cytochrome c biogenesis protein
HEBFMCMF_02047 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
HEBFMCMF_02048 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
HEBFMCMF_02049 7.2e-74 yneK S Protein of unknown function (DUF2621)
HEBFMCMF_02050 5.9e-64 hspX O Spore coat protein
HEBFMCMF_02051 3.9e-19 sspP S Belongs to the SspP family
HEBFMCMF_02052 2.2e-14 sspO S Belongs to the SspO family
HEBFMCMF_02053 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HEBFMCMF_02054 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HEBFMCMF_02056 3.1e-08 sspN S Small acid-soluble spore protein N family
HEBFMCMF_02057 3.9e-35 tlp S Belongs to the Tlp family
HEBFMCMF_02058 1.6e-73 yneP S Thioesterase-like superfamily
HEBFMCMF_02059 2.9e-53 yneQ
HEBFMCMF_02060 4.1e-49 yneR S Belongs to the HesB IscA family
HEBFMCMF_02061 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HEBFMCMF_02062 6.6e-69 yccU S CoA-binding protein
HEBFMCMF_02063 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEBFMCMF_02064 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEBFMCMF_02065 2.3e-12
HEBFMCMF_02066 1.3e-57 ynfC
HEBFMCMF_02067 5.3e-251 agcS E Sodium alanine symporter
HEBFMCMF_02068 5.2e-297 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
HEBFMCMF_02070 1.2e-249 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
HEBFMCMF_02071 5e-295 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
HEBFMCMF_02072 2e-79 yngA S membrane
HEBFMCMF_02073 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HEBFMCMF_02074 5.5e-104 yngC S membrane-associated protein
HEBFMCMF_02075 4.3e-233 nrnB S phosphohydrolase (DHH superfamily)
HEBFMCMF_02076 1e-287 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HEBFMCMF_02077 9.2e-136 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HEBFMCMF_02078 7.5e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
HEBFMCMF_02079 1.5e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
HEBFMCMF_02080 1.4e-248 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
HEBFMCMF_02081 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HEBFMCMF_02082 4.8e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
HEBFMCMF_02083 5e-303 yngK T Glycosyl hydrolase-like 10
HEBFMCMF_02084 4e-63 yngL S Protein of unknown function (DUF1360)
HEBFMCMF_02085 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
HEBFMCMF_02086 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEBFMCMF_02087 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEBFMCMF_02088 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEBFMCMF_02089 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEBFMCMF_02090 2.9e-271 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
HEBFMCMF_02091 2.4e-189 yoxA 5.1.3.3 G Aldose 1-epimerase
HEBFMCMF_02092 2.3e-246 yoeA V MATE efflux family protein
HEBFMCMF_02093 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
HEBFMCMF_02095 2.2e-96 L Integrase
HEBFMCMF_02096 3e-34 yoeD G Helix-turn-helix domain
HEBFMCMF_02097 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HEBFMCMF_02098 2.5e-158 gltR1 K Transcriptional regulator
HEBFMCMF_02099 7.2e-186 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HEBFMCMF_02100 1e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HEBFMCMF_02101 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
HEBFMCMF_02102 7.8e-155 gltC K Transcriptional regulator
HEBFMCMF_02103 8.6e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HEBFMCMF_02104 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEBFMCMF_02105 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HEBFMCMF_02106 3.7e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HEBFMCMF_02107 1.3e-37 yoxC S Bacterial protein of unknown function (DUF948)
HEBFMCMF_02108 8.5e-134 yoxB
HEBFMCMF_02109 1.9e-95 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HEBFMCMF_02110 1.2e-124 V ABC-2 family transporter protein
HEBFMCMF_02111 1.3e-94 V ABC-2 family transporter protein
HEBFMCMF_02112 3.3e-140 V AAA domain, putative AbiEii toxin, Type IV TA system
HEBFMCMF_02113 8.6e-80 hpr K helix_turn_helix multiple antibiotic resistance protein
HEBFMCMF_02114 7.6e-233 yoaB EGP Major facilitator Superfamily
HEBFMCMF_02115 6.7e-281 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
HEBFMCMF_02116 1.1e-184 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEBFMCMF_02117 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEBFMCMF_02118 1.1e-33 yoaF
HEBFMCMF_02119 2.2e-08 ywlA S Uncharacterised protein family (UPF0715)
HEBFMCMF_02120 7e-14
HEBFMCMF_02121 8.2e-37 S Protein of unknown function (DUF4025)
HEBFMCMF_02122 7.4e-183 mcpU NT methyl-accepting chemotaxis protein
HEBFMCMF_02123 8.7e-281 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
HEBFMCMF_02124 8.5e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
HEBFMCMF_02125 2.3e-111 yoaK S Membrane
HEBFMCMF_02126 1.2e-196 pelB 4.2.2.10, 4.2.2.2 G Amb_all
HEBFMCMF_02127 1.1e-132 yoqW S Belongs to the SOS response-associated peptidase family
HEBFMCMF_02129 3.8e-234 oxdC 4.1.1.2 G Oxalate decarboxylase
HEBFMCMF_02131 1.9e-146 yoaP 3.1.3.18 K YoaP-like
HEBFMCMF_02132 5.2e-42 yoaQ S Evidence 4 Homologs of previously reported genes of
HEBFMCMF_02134 5e-87
HEBFMCMF_02135 7.1e-172 yoaR V vancomycin resistance protein
HEBFMCMF_02136 7.3e-75 yoaS S Protein of unknown function (DUF2975)
HEBFMCMF_02137 2.1e-29 yozG K Transcriptional regulator
HEBFMCMF_02138 1.4e-147 yoaT S Protein of unknown function (DUF817)
HEBFMCMF_02139 8.6e-159 yoaU K LysR substrate binding domain
HEBFMCMF_02140 2.8e-157 yijE EG EamA-like transporter family
HEBFMCMF_02141 3.1e-40 yoaW
HEBFMCMF_02142 3.8e-116 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HEBFMCMF_02143 5.3e-167 bla 3.5.2.6 V beta-lactamase
HEBFMCMF_02146 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
HEBFMCMF_02147 4e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
HEBFMCMF_02149 1.4e-37 S TM2 domain
HEBFMCMF_02150 1.1e-56 K Helix-turn-helix
HEBFMCMF_02152 6.8e-65 yoaQ S Evidence 4 Homologs of previously reported genes of
HEBFMCMF_02153 3.1e-23 yoqW S Belongs to the SOS response-associated peptidase family
HEBFMCMF_02154 1.9e-23 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HEBFMCMF_02155 1.6e-179 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HEBFMCMF_02156 5.2e-131 purR15 K Bacterial regulatory proteins, lacI family
HEBFMCMF_02157 2.4e-216 3.2.1.86 GT1 G Glycosyl hydrolase family 1
HEBFMCMF_02159 7.5e-95 G Bacterial extracellular solute-binding protein
HEBFMCMF_02160 1.3e-101 P COG0395 ABC-type sugar transport system, permease component
HEBFMCMF_02161 6.8e-103 G Binding-protein-dependent transport system inner membrane component
HEBFMCMF_02162 0.0 rafA 3.2.1.22 G Alpha-galactosidase
HEBFMCMF_02163 5e-107 ypbG 2.7.1.2 GK ROK family
HEBFMCMF_02164 3.3e-85 S SMI1-KNR4 cell-wall
HEBFMCMF_02165 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HEBFMCMF_02166 1.1e-101 yokH G SMI1 / KNR4 family
HEBFMCMF_02167 1.7e-276 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
HEBFMCMF_02168 6.4e-54 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
HEBFMCMF_02169 8e-134 yobQ K helix_turn_helix, arabinose operon control protein
HEBFMCMF_02170 2e-140 yobR 2.3.1.1 J FR47-like protein
HEBFMCMF_02171 3.4e-95 yobS K Transcriptional regulator
HEBFMCMF_02172 6.1e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
HEBFMCMF_02173 8.3e-87 yobU K Bacterial transcription activator, effector binding domain
HEBFMCMF_02174 1.2e-174 yobV K WYL domain
HEBFMCMF_02175 8.8e-93 yobW
HEBFMCMF_02176 1e-51 czrA K transcriptional
HEBFMCMF_02177 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HEBFMCMF_02178 1.5e-92 yozB S membrane
HEBFMCMF_02179 6.4e-145
HEBFMCMF_02180 8e-93 yocC
HEBFMCMF_02181 3.2e-186 yocD 3.4.17.13 V peptidase S66
HEBFMCMF_02182 3.4e-202 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HEBFMCMF_02183 7.1e-198 desK 2.7.13.3 T Histidine kinase
HEBFMCMF_02184 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEBFMCMF_02185 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
HEBFMCMF_02186 0.0 recQ 3.6.4.12 L DNA helicase
HEBFMCMF_02188 3.9e-113 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HEBFMCMF_02189 7.4e-83 dksA T general stress protein
HEBFMCMF_02190 6.4e-54 yocL
HEBFMCMF_02191 6.6e-34
HEBFMCMF_02192 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
HEBFMCMF_02193 1.1e-40 yozN
HEBFMCMF_02194 1.9e-36 yocN
HEBFMCMF_02195 4.2e-56 yozO S Bacterial PH domain
HEBFMCMF_02196 2.7e-31 yozC
HEBFMCMF_02197 1.5e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
HEBFMCMF_02198 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
HEBFMCMF_02199 6e-165 sodA 1.15.1.1 P Superoxide dismutase
HEBFMCMF_02200 1.3e-230 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HEBFMCMF_02201 5.1e-168 yocS S -transporter
HEBFMCMF_02202 1.6e-193 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HEBFMCMF_02203 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HEBFMCMF_02204 0.0 yojO P Von Willebrand factor
HEBFMCMF_02205 1.5e-161 yojN S ATPase family associated with various cellular activities (AAA)
HEBFMCMF_02206 6.6e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HEBFMCMF_02207 3.9e-197 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HEBFMCMF_02208 4.1e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
HEBFMCMF_02209 7.6e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HEBFMCMF_02211 3.6e-244 norM V Multidrug efflux pump
HEBFMCMF_02212 2.1e-149 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HEBFMCMF_02213 2.1e-125 yojG S deacetylase
HEBFMCMF_02214 2.2e-60 yojF S Protein of unknown function (DUF1806)
HEBFMCMF_02215 1.5e-43
HEBFMCMF_02216 1.5e-161 rarD S -transporter
HEBFMCMF_02217 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
HEBFMCMF_02218 2e-09
HEBFMCMF_02219 4.2e-205 gntP EG COG2610 H gluconate symporter and related permeases
HEBFMCMF_02220 8e-64 yodA S tautomerase
HEBFMCMF_02221 4.4e-55 yodB K transcriptional
HEBFMCMF_02222 4.1e-107 yodC C nitroreductase
HEBFMCMF_02223 3.8e-113 mhqD S Carboxylesterase
HEBFMCMF_02224 6.4e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
HEBFMCMF_02225 6.2e-28 S Protein of unknown function (DUF3311)
HEBFMCMF_02226 1.6e-266 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEBFMCMF_02227 1.1e-251 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HEBFMCMF_02228 1.1e-127 yodH Q Methyltransferase
HEBFMCMF_02229 5.2e-24 yodI
HEBFMCMF_02230 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HEBFMCMF_02231 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HEBFMCMF_02232 5.3e-09
HEBFMCMF_02233 3.6e-54 yodL S YodL-like
HEBFMCMF_02234 3.5e-106 yodM 3.6.1.27 I Acid phosphatase homologues
HEBFMCMF_02235 2.8e-24 yozD S YozD-like protein
HEBFMCMF_02237 1.6e-123 yodN
HEBFMCMF_02238 1.4e-36 yozE S Belongs to the UPF0346 family
HEBFMCMF_02239 2.9e-47 yokU S YokU-like protein, putative antitoxin
HEBFMCMF_02240 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
HEBFMCMF_02241 7.9e-154 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
HEBFMCMF_02242 4.2e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
HEBFMCMF_02243 5.2e-116 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HEBFMCMF_02244 1.7e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HEBFMCMF_02245 1.6e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEBFMCMF_02247 1.7e-142 yiiD K acetyltransferase
HEBFMCMF_02248 1.9e-255 cgeD M maturation of the outermost layer of the spore
HEBFMCMF_02249 1e-37 cgeC
HEBFMCMF_02250 1.5e-65 cgeA
HEBFMCMF_02251 4.1e-186 cgeB S Spore maturation protein
HEBFMCMF_02252 5.2e-212 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
HEBFMCMF_02253 5.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
HEBFMCMF_02254 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HEBFMCMF_02255 3.5e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HEBFMCMF_02256 1.6e-70 ypoP K transcriptional
HEBFMCMF_02257 4.9e-222 mepA V MATE efflux family protein
HEBFMCMF_02258 5.5e-29 ypmT S Uncharacterized ympT
HEBFMCMF_02259 1.1e-98 ypmS S protein conserved in bacteria
HEBFMCMF_02260 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
HEBFMCMF_02261 2.7e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HEBFMCMF_02262 3.1e-40 ypmP S Protein of unknown function (DUF2535)
HEBFMCMF_02263 9.7e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HEBFMCMF_02264 1.6e-185 pspF K Transcriptional regulator
HEBFMCMF_02265 4.2e-110 hlyIII S protein, Hemolysin III
HEBFMCMF_02266 1.1e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HEBFMCMF_02267 1.6e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HEBFMCMF_02268 1.5e-154 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HEBFMCMF_02269 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HEBFMCMF_02270 7.8e-114 ypjP S YpjP-like protein
HEBFMCMF_02271 4.1e-144 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
HEBFMCMF_02272 1.7e-75 yphP S Belongs to the UPF0403 family
HEBFMCMF_02273 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HEBFMCMF_02274 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
HEBFMCMF_02275 5.4e-107 ypgQ S phosphohydrolase
HEBFMCMF_02276 2.6e-88 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HEBFMCMF_02277 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HEBFMCMF_02278 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HEBFMCMF_02279 7.9e-31 cspD K Cold-shock protein
HEBFMCMF_02280 3.8e-16 degR
HEBFMCMF_02281 1.8e-30 S Protein of unknown function (DUF2564)
HEBFMCMF_02282 3e-29 ypeQ S Zinc-finger
HEBFMCMF_02283 6.4e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
HEBFMCMF_02284 6.6e-105 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HEBFMCMF_02285 2.7e-67 rnhA 3.1.26.4 L Ribonuclease
HEBFMCMF_02287 4.4e-166 polA 2.7.7.7 L 5'3' exonuclease
HEBFMCMF_02288 2e-07
HEBFMCMF_02289 2.2e-38 ypbS S Protein of unknown function (DUF2533)
HEBFMCMF_02290 0.0 ypbR S Dynamin family
HEBFMCMF_02291 5.1e-87 ypbQ S protein conserved in bacteria
HEBFMCMF_02292 6.3e-207 bcsA Q Naringenin-chalcone synthase
HEBFMCMF_02293 3.8e-227 pbuX F xanthine
HEBFMCMF_02294 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HEBFMCMF_02295 8.7e-292 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HEBFMCMF_02296 2.5e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HEBFMCMF_02297 7e-104 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
HEBFMCMF_02298 8.4e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
HEBFMCMF_02299 8.2e-185 ptxS K transcriptional
HEBFMCMF_02300 1.4e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HEBFMCMF_02301 5.1e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEBFMCMF_02302 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
HEBFMCMF_02304 5.8e-50 yqgA
HEBFMCMF_02305 5.4e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HEBFMCMF_02306 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HEBFMCMF_02307 3.2e-87 ypsA S Belongs to the UPF0398 family
HEBFMCMF_02308 1.6e-235 yprB L RNase_H superfamily
HEBFMCMF_02309 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HEBFMCMF_02310 4.6e-80 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
HEBFMCMF_02311 3.6e-70 hspX O Belongs to the small heat shock protein (HSP20) family
HEBFMCMF_02312 1.2e-48 yppG S YppG-like protein
HEBFMCMF_02314 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
HEBFMCMF_02317 1.7e-187 yppC S Protein of unknown function (DUF2515)
HEBFMCMF_02318 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HEBFMCMF_02319 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
HEBFMCMF_02320 4.7e-93 ypoC
HEBFMCMF_02321 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HEBFMCMF_02322 5.7e-129 dnaD L DNA replication protein DnaD
HEBFMCMF_02323 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
HEBFMCMF_02324 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HEBFMCMF_02325 3.4e-80 ypmB S protein conserved in bacteria
HEBFMCMF_02326 1.9e-22 ypmA S Protein of unknown function (DUF4264)
HEBFMCMF_02327 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HEBFMCMF_02328 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HEBFMCMF_02329 4.4e-155 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HEBFMCMF_02330 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HEBFMCMF_02331 5.6e-183 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HEBFMCMF_02332 4.4e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HEBFMCMF_02333 1.4e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
HEBFMCMF_02334 6.9e-130 bshB1 S proteins, LmbE homologs
HEBFMCMF_02335 6.5e-72 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
HEBFMCMF_02336 1.8e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HEBFMCMF_02337 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
HEBFMCMF_02338 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
HEBFMCMF_02339 1e-142 ypjB S sporulation protein
HEBFMCMF_02340 2e-98 ypjA S membrane
HEBFMCMF_02341 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
HEBFMCMF_02342 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
HEBFMCMF_02343 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
HEBFMCMF_02344 4.2e-77 ypiF S Protein of unknown function (DUF2487)
HEBFMCMF_02345 1.1e-98 ypiB S Belongs to the UPF0302 family
HEBFMCMF_02346 4.1e-234 S COG0457 FOG TPR repeat
HEBFMCMF_02347 2.2e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HEBFMCMF_02348 2.6e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HEBFMCMF_02349 2.7e-202 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HEBFMCMF_02350 5.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HEBFMCMF_02351 1.5e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HEBFMCMF_02352 6.7e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HEBFMCMF_02353 8.1e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HEBFMCMF_02354 3.9e-179 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HEBFMCMF_02355 2e-291 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HEBFMCMF_02356 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HEBFMCMF_02357 5.8e-205 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HEBFMCMF_02358 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HEBFMCMF_02359 1.1e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
HEBFMCMF_02360 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HEBFMCMF_02361 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HEBFMCMF_02362 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HEBFMCMF_02363 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HEBFMCMF_02364 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HEBFMCMF_02365 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
HEBFMCMF_02366 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HEBFMCMF_02367 8.3e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HEBFMCMF_02368 2.3e-136 yphF
HEBFMCMF_02369 1.6e-18 yphE S Protein of unknown function (DUF2768)
HEBFMCMF_02370 5.6e-181 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HEBFMCMF_02371 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HEBFMCMF_02372 1.6e-28 ypzH
HEBFMCMF_02373 2.5e-161 seaA S YIEGIA protein
HEBFMCMF_02374 1.3e-102 yphA
HEBFMCMF_02375 1.4e-07 S YpzI-like protein
HEBFMCMF_02376 1.4e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HEBFMCMF_02377 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
HEBFMCMF_02378 2.8e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HEBFMCMF_02379 1.8e-23 S Family of unknown function (DUF5359)
HEBFMCMF_02380 5e-111 ypfA M Flagellar protein YcgR
HEBFMCMF_02381 4.2e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
HEBFMCMF_02382 7.5e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
HEBFMCMF_02383 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
HEBFMCMF_02384 1.4e-173 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
HEBFMCMF_02385 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HEBFMCMF_02386 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HEBFMCMF_02387 2.6e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
HEBFMCMF_02388 2.8e-81 ypbF S Protein of unknown function (DUF2663)
HEBFMCMF_02389 1.3e-75 ypbE M Lysin motif
HEBFMCMF_02390 2.2e-100 ypbD S metal-dependent membrane protease
HEBFMCMF_02391 9.2e-286 recQ 3.6.4.12 L DNA helicase
HEBFMCMF_02392 1.9e-200 ypbB 5.1.3.1 S protein conserved in bacteria
HEBFMCMF_02393 4.7e-41 fer C Ferredoxin
HEBFMCMF_02394 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HEBFMCMF_02395 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEBFMCMF_02396 5.9e-135 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HEBFMCMF_02397 8.3e-199 rsiX
HEBFMCMF_02398 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
HEBFMCMF_02399 0.0 resE 2.7.13.3 T Histidine kinase
HEBFMCMF_02400 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEBFMCMF_02401 6.7e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HEBFMCMF_02402 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
HEBFMCMF_02403 4.8e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HEBFMCMF_02404 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HEBFMCMF_02405 1.9e-87 spmB S Spore maturation protein
HEBFMCMF_02406 3.5e-103 spmA S Spore maturation protein
HEBFMCMF_02407 8.9e-212 dacB 3.4.16.4 M Belongs to the peptidase S11 family
HEBFMCMF_02408 7.6e-97 ypuI S Protein of unknown function (DUF3907)
HEBFMCMF_02409 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HEBFMCMF_02410 6.4e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HEBFMCMF_02411 4.6e-91 ypuF S Domain of unknown function (DUF309)
HEBFMCMF_02412 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEBFMCMF_02413 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HEBFMCMF_02414 1.9e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HEBFMCMF_02415 1.7e-114 ribE 2.5.1.9 H Riboflavin synthase
HEBFMCMF_02416 1.3e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HEBFMCMF_02417 6e-55 ypuD
HEBFMCMF_02418 3.5e-97 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HEBFMCMF_02419 6.6e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
HEBFMCMF_02420 9.1e-16 S SNARE associated Golgi protein
HEBFMCMF_02422 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HEBFMCMF_02423 1.3e-149 ypuA S Secreted protein
HEBFMCMF_02424 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HEBFMCMF_02425 1.4e-273 spoVAF EG Stage V sporulation protein AF
HEBFMCMF_02426 1.4e-110 spoVAEA S stage V sporulation protein
HEBFMCMF_02427 2.2e-57 spoVAEB S stage V sporulation protein
HEBFMCMF_02428 1.3e-190 spoVAD I Stage V sporulation protein AD
HEBFMCMF_02429 2.3e-78 spoVAC S stage V sporulation protein AC
HEBFMCMF_02430 1e-67 spoVAB S Stage V sporulation protein AB
HEBFMCMF_02431 9.6e-112 spoVAA S Stage V sporulation protein AA
HEBFMCMF_02432 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEBFMCMF_02433 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HEBFMCMF_02434 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
HEBFMCMF_02435 2.4e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
HEBFMCMF_02436 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HEBFMCMF_02437 3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HEBFMCMF_02438 2.6e-166 xerD L recombinase XerD
HEBFMCMF_02439 3.7e-37 S Protein of unknown function (DUF4227)
HEBFMCMF_02440 2.4e-80 fur P Belongs to the Fur family
HEBFMCMF_02441 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HEBFMCMF_02442 2.1e-29 yqkK
HEBFMCMF_02443 5.5e-242 mleA 1.1.1.38 C malic enzyme
HEBFMCMF_02444 3.1e-235 mleN C Na H antiporter
HEBFMCMF_02445 4.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
HEBFMCMF_02446 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
HEBFMCMF_02447 4.5e-58 ansR K Transcriptional regulator
HEBFMCMF_02448 4.3e-222 yqxK 3.6.4.12 L DNA helicase
HEBFMCMF_02449 2.6e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
HEBFMCMF_02451 5.3e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
HEBFMCMF_02452 3.1e-12 yqkE S Protein of unknown function (DUF3886)
HEBFMCMF_02453 8.5e-173 yqkD S COG1073 Hydrolases of the alpha beta superfamily
HEBFMCMF_02454 9.4e-39 yqkC S Protein of unknown function (DUF2552)
HEBFMCMF_02455 2.8e-54 yqkB S Belongs to the HesB IscA family
HEBFMCMF_02456 1.7e-193 yqkA K GrpB protein
HEBFMCMF_02457 8.9e-59 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
HEBFMCMF_02458 1.8e-86 yqjY K acetyltransferase
HEBFMCMF_02459 4.8e-49 S YolD-like protein
HEBFMCMF_02460 4.6e-238 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HEBFMCMF_02462 1.7e-224 yqjV G Major Facilitator Superfamily
HEBFMCMF_02464 8.8e-71 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEBFMCMF_02465 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
HEBFMCMF_02466 7.9e-260 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HEBFMCMF_02467 5e-142 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
HEBFMCMF_02468 1.3e-179 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
HEBFMCMF_02469 4.7e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEBFMCMF_02470 0.0 rocB E arginine degradation protein
HEBFMCMF_02471 2.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HEBFMCMF_02472 1.4e-144 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HEBFMCMF_02473 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HEBFMCMF_02474 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HEBFMCMF_02475 5.2e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HEBFMCMF_02476 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HEBFMCMF_02477 1.6e-235 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HEBFMCMF_02478 4.5e-24 yqzJ
HEBFMCMF_02479 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HEBFMCMF_02480 3.6e-142 yqjF S Uncharacterized conserved protein (COG2071)
HEBFMCMF_02481 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
HEBFMCMF_02482 2.2e-290 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HEBFMCMF_02483 1e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
HEBFMCMF_02485 1.4e-98 yqjB S protein conserved in bacteria
HEBFMCMF_02486 3.3e-175 yqjA S Putative aromatic acid exporter C-terminal domain
HEBFMCMF_02487 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HEBFMCMF_02488 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
HEBFMCMF_02489 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
HEBFMCMF_02490 9.3e-77 yqiW S Belongs to the UPF0403 family
HEBFMCMF_02491 2.6e-166 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HEBFMCMF_02492 2.3e-207 norA EGP Major facilitator Superfamily
HEBFMCMF_02493 2.2e-151 bmrR K helix_turn_helix, mercury resistance
HEBFMCMF_02494 4.4e-228 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HEBFMCMF_02495 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HEBFMCMF_02496 7.2e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HEBFMCMF_02497 9.8e-269 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HEBFMCMF_02498 1e-201 buk 2.7.2.7 C Belongs to the acetokinase family
HEBFMCMF_02499 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
HEBFMCMF_02500 3.9e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
HEBFMCMF_02501 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
HEBFMCMF_02502 4e-34 yqzF S Protein of unknown function (DUF2627)
HEBFMCMF_02503 3e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HEBFMCMF_02504 6.3e-276 prpD 4.2.1.79 S 2-methylcitrate dehydratase
HEBFMCMF_02505 2.4e-209 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
HEBFMCMF_02506 1.8e-212 mmgC I acyl-CoA dehydrogenase
HEBFMCMF_02507 2.3e-156 hbdA 1.1.1.157 I Dehydrogenase
HEBFMCMF_02508 7.7e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
HEBFMCMF_02509 1.5e-132 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HEBFMCMF_02510 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
HEBFMCMF_02511 6e-27
HEBFMCMF_02512 1.3e-212 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HEBFMCMF_02514 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HEBFMCMF_02515 8e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
HEBFMCMF_02516 0.0 recN L May be involved in recombinational repair of damaged DNA
HEBFMCMF_02517 1.7e-78 argR K Regulates arginine biosynthesis genes
HEBFMCMF_02518 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
HEBFMCMF_02519 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HEBFMCMF_02520 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HEBFMCMF_02521 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEBFMCMF_02522 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEBFMCMF_02523 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HEBFMCMF_02524 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HEBFMCMF_02525 2.1e-67 yqhY S protein conserved in bacteria
HEBFMCMF_02526 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HEBFMCMF_02527 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HEBFMCMF_02528 3.8e-90 spoIIIAH S SpoIIIAH-like protein
HEBFMCMF_02529 3.6e-107 spoIIIAG S stage III sporulation protein AG
HEBFMCMF_02530 1.2e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
HEBFMCMF_02531 8.4e-197 spoIIIAE S stage III sporulation protein AE
HEBFMCMF_02532 2.3e-58 spoIIIAD S Stage III sporulation protein AD
HEBFMCMF_02533 7.6e-29 spoIIIAC S stage III sporulation protein AC
HEBFMCMF_02534 1.1e-84 spoIIIAB S Stage III sporulation protein
HEBFMCMF_02535 8.8e-170 spoIIIAA S stage III sporulation protein AA
HEBFMCMF_02536 7.9e-37 yqhV S Protein of unknown function (DUF2619)
HEBFMCMF_02537 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HEBFMCMF_02538 3.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HEBFMCMF_02539 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
HEBFMCMF_02540 2.3e-93 yqhR S Conserved membrane protein YqhR
HEBFMCMF_02541 2e-172 yqhQ S Protein of unknown function (DUF1385)
HEBFMCMF_02542 2.2e-61 yqhP
HEBFMCMF_02543 1.5e-163 yqhO S esterase of the alpha-beta hydrolase superfamily
HEBFMCMF_02544 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HEBFMCMF_02545 2.2e-159 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HEBFMCMF_02546 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
HEBFMCMF_02547 2.9e-284 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HEBFMCMF_02548 1.4e-253 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HEBFMCMF_02549 2.1e-207 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
HEBFMCMF_02550 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HEBFMCMF_02551 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
HEBFMCMF_02552 1.2e-24 sinI S Anti-repressor SinI
HEBFMCMF_02553 1e-54 sinR K transcriptional
HEBFMCMF_02554 1.2e-140 tasA S Cell division protein FtsN
HEBFMCMF_02555 6.7e-59 sipW 3.4.21.89 U Signal peptidase
HEBFMCMF_02556 2.7e-116 yqxM
HEBFMCMF_02557 7.3e-54 yqzG S Protein of unknown function (DUF3889)
HEBFMCMF_02558 4.4e-25 yqzE S YqzE-like protein
HEBFMCMF_02559 4e-44 S ComG operon protein 7
HEBFMCMF_02560 5.9e-35 comGF U Putative Competence protein ComGF
HEBFMCMF_02561 1.1e-59 comGE
HEBFMCMF_02562 4.4e-71 gspH NU protein transport across the cell outer membrane
HEBFMCMF_02563 1.4e-47 comGC U Required for transformation and DNA binding
HEBFMCMF_02564 7.8e-175 comGB NU COG1459 Type II secretory pathway, component PulF
HEBFMCMF_02565 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HEBFMCMF_02568 7.2e-175 corA P Mg2 transporter protein
HEBFMCMF_02569 7.5e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HEBFMCMF_02570 7e-150 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HEBFMCMF_02572 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
HEBFMCMF_02573 1.8e-37 yqgY S Protein of unknown function (DUF2626)
HEBFMCMF_02574 1.2e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HEBFMCMF_02575 8.9e-23 yqgW S Protein of unknown function (DUF2759)
HEBFMCMF_02576 6.9e-50 yqgV S Thiamine-binding protein
HEBFMCMF_02577 3.9e-198 yqgU
HEBFMCMF_02578 2.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
HEBFMCMF_02579 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HEBFMCMF_02580 4.4e-180 glcK 2.7.1.2 G Glucokinase
HEBFMCMF_02581 3.1e-33 yqgQ S Protein conserved in bacteria
HEBFMCMF_02582 1.3e-266 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
HEBFMCMF_02583 2.5e-09 yqgO
HEBFMCMF_02584 2.5e-103 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HEBFMCMF_02585 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HEBFMCMF_02586 2.3e-201 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
HEBFMCMF_02588 9.2e-51 yqzD
HEBFMCMF_02589 2.1e-71 yqzC S YceG-like family
HEBFMCMF_02590 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HEBFMCMF_02591 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HEBFMCMF_02592 4.4e-158 pstA P Phosphate transport system permease
HEBFMCMF_02593 7.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
HEBFMCMF_02594 1.3e-149 pstS P Phosphate
HEBFMCMF_02595 0.0 pbpA 3.4.16.4 M penicillin-binding protein
HEBFMCMF_02596 2.8e-230 yqgE EGP Major facilitator superfamily
HEBFMCMF_02597 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
HEBFMCMF_02598 4e-73 yqgC S protein conserved in bacteria
HEBFMCMF_02599 1.9e-133 yqgB S Protein of unknown function (DUF1189)
HEBFMCMF_02600 2.2e-75 yqgA
HEBFMCMF_02601 5.2e-47 yqfZ M LysM domain
HEBFMCMF_02602 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HEBFMCMF_02603 4.3e-62 yqfX S membrane
HEBFMCMF_02604 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
HEBFMCMF_02605 4.2e-77 zur P Belongs to the Fur family
HEBFMCMF_02606 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HEBFMCMF_02607 2.1e-36 yqfT S Protein of unknown function (DUF2624)
HEBFMCMF_02608 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HEBFMCMF_02609 1.2e-241 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HEBFMCMF_02610 2.9e-14 yqfQ S YqfQ-like protein
HEBFMCMF_02611 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HEBFMCMF_02612 5.6e-211 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HEBFMCMF_02613 2.6e-115 trmK 2.1.1.217 S SAM-dependent methyltransferase
HEBFMCMF_02614 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
HEBFMCMF_02615 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HEBFMCMF_02616 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HEBFMCMF_02617 4.5e-88 yaiI S Belongs to the UPF0178 family
HEBFMCMF_02618 9.9e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HEBFMCMF_02619 4.5e-112 ccpN K CBS domain
HEBFMCMF_02620 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HEBFMCMF_02621 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HEBFMCMF_02622 6.3e-145 recO L Involved in DNA repair and RecF pathway recombination
HEBFMCMF_02623 8.4e-19 S YqzL-like protein
HEBFMCMF_02624 4e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HEBFMCMF_02625 2.1e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HEBFMCMF_02626 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HEBFMCMF_02627 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HEBFMCMF_02628 0.0 yqfF S membrane-associated HD superfamily hydrolase
HEBFMCMF_02630 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
HEBFMCMF_02631 2.1e-184 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
HEBFMCMF_02632 2.7e-45 yqfC S sporulation protein YqfC
HEBFMCMF_02633 9e-21 yqfB
HEBFMCMF_02634 4.3e-122 yqfA S UPF0365 protein
HEBFMCMF_02635 5.4e-229 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
HEBFMCMF_02636 2.5e-61 yqeY S Yqey-like protein
HEBFMCMF_02637 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HEBFMCMF_02638 3.7e-158 yqeW P COG1283 Na phosphate symporter
HEBFMCMF_02639 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
HEBFMCMF_02640 3.6e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HEBFMCMF_02641 5.4e-175 prmA J Methylates ribosomal protein L11
HEBFMCMF_02642 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HEBFMCMF_02643 0.0 dnaK O Heat shock 70 kDa protein
HEBFMCMF_02644 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HEBFMCMF_02645 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HEBFMCMF_02646 1.8e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
HEBFMCMF_02647 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HEBFMCMF_02648 1e-54 yqxA S Protein of unknown function (DUF3679)
HEBFMCMF_02649 1.5e-222 spoIIP M stage II sporulation protein P
HEBFMCMF_02650 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HEBFMCMF_02651 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
HEBFMCMF_02652 1.3e-188 holA 2.7.7.7 L DNA polymerase III delta subunit
HEBFMCMF_02653 4.1e-15 S YqzM-like protein
HEBFMCMF_02654 0.0 comEC S Competence protein ComEC
HEBFMCMF_02655 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
HEBFMCMF_02656 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
HEBFMCMF_02657 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEBFMCMF_02658 2.9e-139 yqeM Q Methyltransferase
HEBFMCMF_02659 6.9e-62 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HEBFMCMF_02660 7.4e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HEBFMCMF_02661 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HEBFMCMF_02662 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
HEBFMCMF_02663 2.7e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HEBFMCMF_02664 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HEBFMCMF_02665 5.3e-95 yqeG S hydrolase of the HAD superfamily
HEBFMCMF_02667 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
HEBFMCMF_02668 1.6e-132 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HEBFMCMF_02669 4e-105 yqeD S SNARE associated Golgi protein
HEBFMCMF_02670 1.2e-168 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
HEBFMCMF_02671 2.3e-133 yqeB
HEBFMCMF_02672 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
HEBFMCMF_02673 2.8e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEBFMCMF_02674 5.3e-62 napB K helix_turn_helix multiple antibiotic resistance protein
HEBFMCMF_02675 1.2e-221 yfjF U Belongs to the major facilitator superfamily
HEBFMCMF_02676 1.2e-277 cisA2 L Recombinase
HEBFMCMF_02677 4e-177 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HEBFMCMF_02680 4.3e-203 S Aspartate phosphatase response regulator
HEBFMCMF_02682 1.1e-60 S TraX protein
HEBFMCMF_02684 1.2e-305 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HEBFMCMF_02685 1.7e-81 S SMI1-KNR4 cell-wall
HEBFMCMF_02686 2.5e-119 EGP Necrosis inducing protein (NPP1)
HEBFMCMF_02687 3.9e-27 K Bacterial regulatory proteins, tetR family
HEBFMCMF_02688 2.6e-54 1.6.5.2 GM NmrA-like family
HEBFMCMF_02689 3.7e-126 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HEBFMCMF_02690 1.3e-27 S phage terminase, large subunit
HEBFMCMF_02691 3e-43 yqaS L DNA packaging
HEBFMCMF_02692 6.9e-26 yqaS L DNA packaging
HEBFMCMF_02694 6.3e-26 cotD S Inner spore coat protein D
HEBFMCMF_02695 1.9e-40 L Transposase
HEBFMCMF_02697 7.6e-160 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
HEBFMCMF_02698 5.9e-89 K Transcriptional regulator PadR-like family
HEBFMCMF_02699 3.9e-101 adk 2.7.4.3 F adenylate kinase activity
HEBFMCMF_02701 1.2e-94 yqaB E IrrE N-terminal-like domain
HEBFMCMF_02702 6.1e-62 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEBFMCMF_02703 9e-237 yrkQ T Histidine kinase
HEBFMCMF_02704 1.1e-127 T Transcriptional regulator
HEBFMCMF_02705 4.1e-223 yrkO P Protein of unknown function (DUF418)
HEBFMCMF_02706 1.1e-103 yrkN K Acetyltransferase (GNAT) family
HEBFMCMF_02707 1.5e-97 ywrO S Flavodoxin-like fold
HEBFMCMF_02708 2.8e-79 S Protein of unknown function with HXXEE motif
HEBFMCMF_02709 1.7e-100 yrkJ S membrane transporter protein
HEBFMCMF_02710 5.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
HEBFMCMF_02711 1.4e-206 yrkH P Rhodanese Homology Domain
HEBFMCMF_02712 4.6e-97 yrkF OP Belongs to the sulfur carrier protein TusA family
HEBFMCMF_02713 2.8e-82 yrkE O DsrE/DsrF/DrsH-like family
HEBFMCMF_02714 7.8e-39 yrkD S protein conserved in bacteria
HEBFMCMF_02715 1.3e-107 yrkC G Cupin domain
HEBFMCMF_02716 3.4e-149 bltR K helix_turn_helix, mercury resistance
HEBFMCMF_02717 1e-210 blt EGP Major facilitator Superfamily
HEBFMCMF_02718 2.2e-81 bltD 2.3.1.57 K FR47-like protein
HEBFMCMF_02719 3.6e-233 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HEBFMCMF_02720 3.9e-16 S YrzO-like protein
HEBFMCMF_02721 2.4e-170 yrdR EG EamA-like transporter family
HEBFMCMF_02722 3e-159 yrdQ K Transcriptional regulator
HEBFMCMF_02723 5.6e-197 trkA P Oxidoreductase
HEBFMCMF_02724 1.3e-157 czcD P COG1230 Co Zn Cd efflux system component
HEBFMCMF_02725 8.6e-66 yodA S tautomerase
HEBFMCMF_02726 3.6e-117 gltR K LysR substrate binding domain
HEBFMCMF_02727 6e-228 brnQ E Component of the transport system for branched-chain amino acids
HEBFMCMF_02728 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
HEBFMCMF_02729 2.8e-137 azlC E AzlC protein
HEBFMCMF_02730 6.3e-79 bkdR K helix_turn_helix ASNC type
HEBFMCMF_02731 2.2e-32 yrdF K ribonuclease inhibitor
HEBFMCMF_02732 7.8e-230 cypA C Cytochrome P450
HEBFMCMF_02733 1.2e-100 yrdC 3.5.1.19 Q Isochorismatase family
HEBFMCMF_02734 1.9e-57 S Protein of unknown function (DUF2568)
HEBFMCMF_02735 6.4e-90 yrdA S DinB family
HEBFMCMF_02736 1e-164 aadK G Streptomycin adenylyltransferase
HEBFMCMF_02737 6.4e-193 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HEBFMCMF_02738 4.1e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HEBFMCMF_02739 2.8e-123 yrpD S Domain of unknown function, YrpD
HEBFMCMF_02741 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HEBFMCMF_02742 2.4e-95 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
HEBFMCMF_02743 1.9e-186 yrpG C Aldo/keto reductase family
HEBFMCMF_02744 3.6e-225 yraO C Citrate transporter
HEBFMCMF_02745 3.4e-163 yraN K Transcriptional regulator
HEBFMCMF_02746 6.1e-202 yraM S PrpF protein
HEBFMCMF_02747 3.3e-13 yraM S PrpF protein
HEBFMCMF_02748 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HEBFMCMF_02749 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEBFMCMF_02750 2e-149 S Alpha beta hydrolase
HEBFMCMF_02751 4.9e-60 T sh3 domain protein
HEBFMCMF_02752 2.4e-61 T sh3 domain protein
HEBFMCMF_02754 3.8e-66 E Glyoxalase-like domain
HEBFMCMF_02755 1.5e-36 yraG
HEBFMCMF_02756 6.4e-63 yraF M Spore coat protein
HEBFMCMF_02757 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HEBFMCMF_02758 7.5e-26 yraE
HEBFMCMF_02759 1.1e-49 yraD M Spore coat protein
HEBFMCMF_02760 1.8e-45 yraB K helix_turn_helix, mercury resistance
HEBFMCMF_02761 3.2e-29 yphJ 4.1.1.44 S peroxiredoxin activity
HEBFMCMF_02762 4.3e-197 adhA 1.1.1.1 C alcohol dehydrogenase
HEBFMCMF_02763 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
HEBFMCMF_02764 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HEBFMCMF_02765 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HEBFMCMF_02766 4.4e-117 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HEBFMCMF_02767 6.9e-81 levE 2.7.1.202 G PTS system mannose fructose sorbose family
HEBFMCMF_02768 1.9e-74 levD 2.7.1.202 G PTS system fructose IIA component
HEBFMCMF_02769 0.0 levR K PTS system fructose IIA component
HEBFMCMF_02770 3e-254 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HEBFMCMF_02771 3.6e-106 yrhP E LysE type translocator
HEBFMCMF_02772 3.5e-149 yrhO K Archaeal transcriptional regulator TrmB
HEBFMCMF_02773 1.6e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HEBFMCMF_02774 3.8e-151 rsiV S Protein of unknown function (DUF3298)
HEBFMCMF_02775 0.0 yrhL I Acyltransferase family
HEBFMCMF_02776 1.4e-44 yrhK S YrhK-like protein
HEBFMCMF_02777 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HEBFMCMF_02778 1.8e-104 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
HEBFMCMF_02779 3.2e-95 yrhH Q methyltransferase
HEBFMCMF_02782 1.8e-142 focA P Formate nitrite
HEBFMCMF_02784 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
HEBFMCMF_02785 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HEBFMCMF_02786 1.2e-77 yrhD S Protein of unknown function (DUF1641)
HEBFMCMF_02787 4.6e-35 yrhC S YrhC-like protein
HEBFMCMF_02788 1.1e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HEBFMCMF_02789 6.1e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
HEBFMCMF_02790 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HEBFMCMF_02791 1.7e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
HEBFMCMF_02792 1e-25 yrzA S Protein of unknown function (DUF2536)
HEBFMCMF_02793 4.2e-63 yrrS S Protein of unknown function (DUF1510)
HEBFMCMF_02794 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
HEBFMCMF_02795 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HEBFMCMF_02796 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
HEBFMCMF_02797 2.7e-246 yegQ O COG0826 Collagenase and related proteases
HEBFMCMF_02798 2.9e-173 yegQ O Peptidase U32
HEBFMCMF_02799 2.3e-119 yrrM 2.1.1.104 S O-methyltransferase
HEBFMCMF_02800 8.2e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HEBFMCMF_02801 1.2e-45 yrzB S Belongs to the UPF0473 family
HEBFMCMF_02802 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HEBFMCMF_02803 1.7e-41 yrzL S Belongs to the UPF0297 family
HEBFMCMF_02804 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HEBFMCMF_02805 2.7e-170 yrrI S AI-2E family transporter
HEBFMCMF_02806 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HEBFMCMF_02807 4.8e-143 glnH ET Belongs to the bacterial solute-binding protein 3 family
HEBFMCMF_02808 1.8e-108 gluC P ABC transporter
HEBFMCMF_02809 7.6e-107 glnP P ABC transporter
HEBFMCMF_02810 8e-08 S Protein of unknown function (DUF3918)
HEBFMCMF_02811 9.8e-31 yrzR
HEBFMCMF_02812 1.8e-83 yrrD S protein conserved in bacteria
HEBFMCMF_02813 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HEBFMCMF_02814 1.4e-15 S COG0457 FOG TPR repeat
HEBFMCMF_02815 2.5e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HEBFMCMF_02816 2e-211 iscS 2.8.1.7 E Cysteine desulfurase
HEBFMCMF_02817 1.2e-70 cymR K Transcriptional regulator
HEBFMCMF_02818 2e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HEBFMCMF_02819 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HEBFMCMF_02820 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HEBFMCMF_02821 2e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
HEBFMCMF_02823 2.6e-259 lytH 3.5.1.28 M COG3103 SH3 domain protein
HEBFMCMF_02824 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HEBFMCMF_02825 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HEBFMCMF_02826 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HEBFMCMF_02827 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HEBFMCMF_02828 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
HEBFMCMF_02829 8.6e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
HEBFMCMF_02830 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HEBFMCMF_02831 1.6e-48 yrzD S Post-transcriptional regulator
HEBFMCMF_02832 2.4e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEBFMCMF_02833 1.2e-112 yrbG S membrane
HEBFMCMF_02834 1.2e-74 yrzE S Protein of unknown function (DUF3792)
HEBFMCMF_02835 1.1e-38 yajC U Preprotein translocase subunit YajC
HEBFMCMF_02836 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HEBFMCMF_02837 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HEBFMCMF_02838 2.6e-18 yrzS S Protein of unknown function (DUF2905)
HEBFMCMF_02839 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HEBFMCMF_02840 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HEBFMCMF_02841 4.8e-93 bofC S BofC C-terminal domain
HEBFMCMF_02842 5.3e-253 csbX EGP Major facilitator Superfamily
HEBFMCMF_02843 6.3e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HEBFMCMF_02844 2.1e-117 yrzF T serine threonine protein kinase
HEBFMCMF_02846 1.5e-50 S Family of unknown function (DUF5412)
HEBFMCMF_02847 3.8e-260 alsT E Sodium alanine symporter
HEBFMCMF_02848 8e-126 yebC K transcriptional regulatory protein
HEBFMCMF_02849 2.2e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HEBFMCMF_02850 1.8e-156 safA M spore coat assembly protein SafA
HEBFMCMF_02851 2.8e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HEBFMCMF_02852 7.3e-158 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
HEBFMCMF_02853 2.7e-307 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HEBFMCMF_02854 2.2e-226 nifS 2.8.1.7 E Cysteine desulfurase
HEBFMCMF_02855 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
HEBFMCMF_02856 1e-162 pheA 4.2.1.51 E Prephenate dehydratase
HEBFMCMF_02857 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
HEBFMCMF_02858 5.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HEBFMCMF_02859 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
HEBFMCMF_02860 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HEBFMCMF_02861 4.1e-56 ysxB J ribosomal protein
HEBFMCMF_02862 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HEBFMCMF_02863 2e-160 spoIVFB S Stage IV sporulation protein
HEBFMCMF_02864 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
HEBFMCMF_02865 4.7e-143 minD D Belongs to the ParA family
HEBFMCMF_02866 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HEBFMCMF_02867 1.4e-84 mreD M shape-determining protein
HEBFMCMF_02868 1.1e-156 mreC M Involved in formation and maintenance of cell shape
HEBFMCMF_02869 1.8e-184 mreB D Rod shape-determining protein MreB
HEBFMCMF_02870 6.5e-125 radC E Belongs to the UPF0758 family
HEBFMCMF_02871 2.8e-102 maf D septum formation protein Maf
HEBFMCMF_02872 4.9e-166 spoIIB S Sporulation related domain
HEBFMCMF_02873 1.5e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HEBFMCMF_02874 2.8e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HEBFMCMF_02875 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HEBFMCMF_02876 1.6e-25
HEBFMCMF_02877 1.5e-197 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HEBFMCMF_02878 6e-204 spoVID M stage VI sporulation protein D
HEBFMCMF_02879 5.6e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HEBFMCMF_02880 6.2e-182 hemB 4.2.1.24 H Belongs to the ALAD family
HEBFMCMF_02881 7.9e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HEBFMCMF_02882 8.7e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HEBFMCMF_02883 3.6e-146 hemX O cytochrome C
HEBFMCMF_02884 1e-246 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HEBFMCMF_02885 5.4e-89 ysxD
HEBFMCMF_02886 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
HEBFMCMF_02887 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HEBFMCMF_02888 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
HEBFMCMF_02889 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HEBFMCMF_02890 4.1e-226 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HEBFMCMF_02891 1.1e-186 ysoA H Tetratricopeptide repeat
HEBFMCMF_02892 9e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HEBFMCMF_02893 8.2e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HEBFMCMF_02894 5.7e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HEBFMCMF_02895 4.2e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HEBFMCMF_02896 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HEBFMCMF_02897 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
HEBFMCMF_02898 0.0 ilvB 2.2.1.6 E Acetolactate synthase
HEBFMCMF_02900 7.9e-79 ysnE K acetyltransferase
HEBFMCMF_02901 4.2e-131 ysnF S protein conserved in bacteria
HEBFMCMF_02903 1.4e-92 ysnB S Phosphoesterase
HEBFMCMF_02904 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HEBFMCMF_02905 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HEBFMCMF_02906 6.5e-196 gerM S COG5401 Spore germination protein
HEBFMCMF_02907 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HEBFMCMF_02908 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
HEBFMCMF_02909 3.3e-30 gerE K Transcriptional regulator
HEBFMCMF_02910 6.5e-78 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
HEBFMCMF_02911 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HEBFMCMF_02912 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HEBFMCMF_02913 2.4e-107 sdhC C succinate dehydrogenase
HEBFMCMF_02914 1.2e-79 yslB S Protein of unknown function (DUF2507)
HEBFMCMF_02915 1.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HEBFMCMF_02916 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HEBFMCMF_02917 2e-52 trxA O Belongs to the thioredoxin family
HEBFMCMF_02918 1.4e-302 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HEBFMCMF_02920 3.5e-177 etfA C Electron transfer flavoprotein
HEBFMCMF_02921 4.5e-135 etfB C Electron transfer flavoprotein
HEBFMCMF_02922 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HEBFMCMF_02923 3.8e-94 fadR K Transcriptional regulator
HEBFMCMF_02924 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HEBFMCMF_02925 7.3e-68 yshE S membrane
HEBFMCMF_02926 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HEBFMCMF_02927 0.0 polX L COG1796 DNA polymerase IV (family X)
HEBFMCMF_02928 1.3e-85 cvpA S membrane protein, required for colicin V production
HEBFMCMF_02929 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HEBFMCMF_02930 5.4e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEBFMCMF_02931 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HEBFMCMF_02932 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HEBFMCMF_02933 9.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEBFMCMF_02934 2.6e-32 sspI S Belongs to the SspI family
HEBFMCMF_02935 1e-204 ysfB KT regulator
HEBFMCMF_02936 6.7e-262 glcD 1.1.3.15 C Glycolate oxidase subunit
HEBFMCMF_02937 2.6e-255 glcF C Glycolate oxidase
HEBFMCMF_02938 3.6e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
HEBFMCMF_02939 0.0 cstA T Carbon starvation protein
HEBFMCMF_02940 5.1e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
HEBFMCMF_02941 2.9e-143 araQ G transport system permease
HEBFMCMF_02942 1.4e-167 araP G carbohydrate transport
HEBFMCMF_02943 8.1e-254 araN G carbohydrate transport
HEBFMCMF_02944 4.8e-221 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HEBFMCMF_02945 2e-146 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HEBFMCMF_02946 5.5e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HEBFMCMF_02947 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
HEBFMCMF_02948 1.1e-291 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HEBFMCMF_02949 3.1e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HEBFMCMF_02950 6.4e-204 ysdC G COG1363 Cellulase M and related proteins
HEBFMCMF_02951 9.2e-68 ysdB S Sigma-w pathway protein YsdB
HEBFMCMF_02952 7.5e-45 ysdA S Membrane
HEBFMCMF_02953 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HEBFMCMF_02954 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HEBFMCMF_02955 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HEBFMCMF_02957 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HEBFMCMF_02958 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HEBFMCMF_02959 3.1e-130 lytT T COG3279 Response regulator of the LytR AlgR family
HEBFMCMF_02960 0.0 lytS 2.7.13.3 T Histidine kinase
HEBFMCMF_02961 7.3e-149 ysaA S HAD-hyrolase-like
HEBFMCMF_02962 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HEBFMCMF_02963 3.8e-159 ytxC S YtxC-like family
HEBFMCMF_02964 4.9e-111 ytxB S SNARE associated Golgi protein
HEBFMCMF_02965 6.6e-173 dnaI L Primosomal protein DnaI
HEBFMCMF_02966 7.7e-266 dnaB L Membrane attachment protein
HEBFMCMF_02967 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HEBFMCMF_02968 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HEBFMCMF_02969 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HEBFMCMF_02970 9.9e-67 ytcD K Transcriptional regulator
HEBFMCMF_02971 7.3e-201 ytbD EGP Major facilitator Superfamily
HEBFMCMF_02972 8.9e-161 ytbE S reductase
HEBFMCMF_02973 5.4e-96 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HEBFMCMF_02974 1.1e-107 ytaF P Probably functions as a manganese efflux pump
HEBFMCMF_02975 3.9e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HEBFMCMF_02976 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HEBFMCMF_02977 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
HEBFMCMF_02978 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEBFMCMF_02979 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
HEBFMCMF_02980 1.8e-242 icd 1.1.1.42 C isocitrate
HEBFMCMF_02981 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
HEBFMCMF_02982 2.3e-70 yeaL S membrane
HEBFMCMF_02983 2.6e-192 ytvI S sporulation integral membrane protein YtvI
HEBFMCMF_02984 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
HEBFMCMF_02985 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HEBFMCMF_02986 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HEBFMCMF_02987 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HEBFMCMF_02988 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HEBFMCMF_02989 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
HEBFMCMF_02990 0.0 dnaE 2.7.7.7 L DNA polymerase
HEBFMCMF_02991 3.2e-56 ytrH S Sporulation protein YtrH
HEBFMCMF_02992 2.4e-68 ytrI
HEBFMCMF_02993 9.2e-29
HEBFMCMF_02994 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
HEBFMCMF_02995 2.4e-47 ytpI S YtpI-like protein
HEBFMCMF_02996 8e-241 ytoI K transcriptional regulator containing CBS domains
HEBFMCMF_02997 1.1e-156 ytnM S membrane transporter protein
HEBFMCMF_02998 2.5e-236 ytnL 3.5.1.47 E hydrolase activity
HEBFMCMF_02999 6.3e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
HEBFMCMF_03000 1.2e-255 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEBFMCMF_03001 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
HEBFMCMF_03002 1.2e-185 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEBFMCMF_03003 1.1e-141 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HEBFMCMF_03004 4.2e-119 tcyM U Binding-protein-dependent transport system inner membrane component
HEBFMCMF_03005 3.1e-122 tcyL P Binding-protein-dependent transport system inner membrane component
HEBFMCMF_03006 4.2e-144 tcyK M Bacterial periplasmic substrate-binding proteins
HEBFMCMF_03007 2.1e-151 tcyK ET Bacterial periplasmic substrate-binding proteins
HEBFMCMF_03008 4.3e-100 ytmI K Acetyltransferase (GNAT) domain
HEBFMCMF_03009 2.9e-173 ytlI K LysR substrate binding domain
HEBFMCMF_03010 2.6e-130 ytkL S Belongs to the UPF0173 family
HEBFMCMF_03011 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEBFMCMF_03013 2e-266 argH 4.3.2.1 E argininosuccinate lyase
HEBFMCMF_03014 8.7e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HEBFMCMF_03015 3.6e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HEBFMCMF_03016 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HEBFMCMF_03017 5.4e-165 ytxK 2.1.1.72 L DNA methylase
HEBFMCMF_03018 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HEBFMCMF_03019 1.9e-69 ytfJ S Sporulation protein YtfJ
HEBFMCMF_03020 3.6e-115 ytfI S Protein of unknown function (DUF2953)
HEBFMCMF_03021 2.5e-86 yteJ S RDD family
HEBFMCMF_03022 3.5e-180 sppA OU signal peptide peptidase SppA
HEBFMCMF_03023 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HEBFMCMF_03024 0.0 ytcJ S amidohydrolase
HEBFMCMF_03025 1.2e-304 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HEBFMCMF_03026 2e-29 sspB S spore protein
HEBFMCMF_03027 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HEBFMCMF_03028 8.6e-207 iscS2 2.8.1.7 E Cysteine desulfurase
HEBFMCMF_03029 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
HEBFMCMF_03030 5.4e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HEBFMCMF_03031 3.5e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HEBFMCMF_03032 3.4e-109 yttP K Transcriptional regulator
HEBFMCMF_03033 2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
HEBFMCMF_03034 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
HEBFMCMF_03035 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HEBFMCMF_03037 8.8e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HEBFMCMF_03038 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HEBFMCMF_03039 1.8e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HEBFMCMF_03040 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
HEBFMCMF_03041 5.4e-225 acuC BQ histone deacetylase
HEBFMCMF_03042 1.4e-125 motS N Flagellar motor protein
HEBFMCMF_03043 6e-146 motA N flagellar motor
HEBFMCMF_03044 1.7e-182 ccpA K catabolite control protein A
HEBFMCMF_03045 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HEBFMCMF_03046 1.7e-54 ytxJ O Protein of unknown function (DUF2847)
HEBFMCMF_03047 6.6e-17 ytxH S COG4980 Gas vesicle protein
HEBFMCMF_03048 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HEBFMCMF_03049 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HEBFMCMF_03050 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HEBFMCMF_03051 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HEBFMCMF_03052 9.8e-149 ytpQ S Belongs to the UPF0354 family
HEBFMCMF_03053 4.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HEBFMCMF_03054 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
HEBFMCMF_03055 1.4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HEBFMCMF_03056 2.2e-51 ytzB S small secreted protein
HEBFMCMF_03057 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
HEBFMCMF_03058 8.4e-151 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
HEBFMCMF_03059 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HEBFMCMF_03060 2e-45 ytzH S YtzH-like protein
HEBFMCMF_03061 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
HEBFMCMF_03062 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HEBFMCMF_03063 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HEBFMCMF_03064 1.3e-165 ytlQ
HEBFMCMF_03065 2e-100 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HEBFMCMF_03066 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HEBFMCMF_03067 1.5e-269 pepV 3.5.1.18 E Dipeptidase
HEBFMCMF_03068 2.1e-225 pbuO S permease
HEBFMCMF_03069 1.5e-203 ythQ U Bacterial ABC transporter protein EcsB
HEBFMCMF_03070 9e-130 ythP V ABC transporter
HEBFMCMF_03071 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
HEBFMCMF_03072 1.8e-130 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HEBFMCMF_03073 3.6e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEBFMCMF_03074 1.4e-231 ytfP S HI0933-like protein
HEBFMCMF_03075 7.5e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HEBFMCMF_03076 3.1e-26 yteV S Sporulation protein Cse60
HEBFMCMF_03077 5.3e-116 yteU S Integral membrane protein
HEBFMCMF_03078 1.3e-256 yteT S Oxidoreductase family, C-terminal alpha/beta domain
HEBFMCMF_03079 4.6e-73 yteS G transport
HEBFMCMF_03080 1.2e-216 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HEBFMCMF_03081 1.7e-171 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HEBFMCMF_03082 0.0 ytdP K Transcriptional regulator
HEBFMCMF_03083 6.2e-290 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
HEBFMCMF_03084 1.3e-149 ytcP G COG0395 ABC-type sugar transport system, permease component
HEBFMCMF_03085 2.8e-137 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
HEBFMCMF_03086 1.8e-223 bioI 1.14.14.46 C Cytochrome P450
HEBFMCMF_03087 8.4e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HEBFMCMF_03088 1.3e-125 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HEBFMCMF_03089 1.9e-214 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HEBFMCMF_03090 2.7e-260 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HEBFMCMF_03091 4.4e-140 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HEBFMCMF_03092 2e-171 ytaP S Acetyl xylan esterase (AXE1)
HEBFMCMF_03093 1.9e-189 msmR K Transcriptional regulator
HEBFMCMF_03094 4.3e-247 msmE G Bacterial extracellular solute-binding protein
HEBFMCMF_03095 6.2e-168 amyD P ABC transporter
HEBFMCMF_03096 4.4e-144 amyC P ABC transporter (permease)
HEBFMCMF_03097 2.2e-251 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HEBFMCMF_03098 2.1e-51 ytwF P Sulfurtransferase
HEBFMCMF_03099 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HEBFMCMF_03100 7.7e-55 ytvB S Protein of unknown function (DUF4257)
HEBFMCMF_03101 6.6e-142 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HEBFMCMF_03102 1.3e-210 yttB EGP Major facilitator Superfamily
HEBFMCMF_03103 4.2e-26 yttA 2.7.13.3 S Pfam Transposase IS66
HEBFMCMF_03104 0.0 bceB V ABC transporter (permease)
HEBFMCMF_03105 1.1e-138 bceA V ABC transporter, ATP-binding protein
HEBFMCMF_03106 6.2e-185 T PhoQ Sensor
HEBFMCMF_03107 1.5e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEBFMCMF_03108 1.6e-233 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
HEBFMCMF_03109 3.1e-127 ytrE V ABC transporter, ATP-binding protein
HEBFMCMF_03110 5.3e-149
HEBFMCMF_03111 9.8e-151 P ABC-2 family transporter protein
HEBFMCMF_03112 4.2e-161 ytrB P abc transporter atp-binding protein
HEBFMCMF_03113 5.1e-66 ytrA K GntR family transcriptional regulator
HEBFMCMF_03115 6.7e-41 ytzC S Protein of unknown function (DUF2524)
HEBFMCMF_03116 8.1e-190 yhcC S Fe-S oxidoreductase
HEBFMCMF_03117 4.8e-105 ytqB J Putative rRNA methylase
HEBFMCMF_03118 2.8e-215 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
HEBFMCMF_03119 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
HEBFMCMF_03120 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HEBFMCMF_03121 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
HEBFMCMF_03122 0.0 asnB 6.3.5.4 E Asparagine synthase
HEBFMCMF_03123 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HEBFMCMF_03124 8.8e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HEBFMCMF_03125 1.6e-38 ytmB S Protein of unknown function (DUF2584)
HEBFMCMF_03126 1.1e-146 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HEBFMCMF_03127 1.2e-188 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HEBFMCMF_03128 1.4e-144 ytlC P ABC transporter
HEBFMCMF_03129 6.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HEBFMCMF_03130 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
HEBFMCMF_03131 5.4e-63 ytkC S Bacteriophage holin family
HEBFMCMF_03132 2.1e-76 dps P Belongs to the Dps family
HEBFMCMF_03134 2.4e-72 ytkA S YtkA-like
HEBFMCMF_03135 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HEBFMCMF_03136 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HEBFMCMF_03137 3.6e-41 rpmE2 J Ribosomal protein L31
HEBFMCMF_03138 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
HEBFMCMF_03139 1.8e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HEBFMCMF_03140 1.1e-24 S Domain of Unknown Function (DUF1540)
HEBFMCMF_03141 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HEBFMCMF_03142 2e-231 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HEBFMCMF_03143 2.1e-137 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HEBFMCMF_03144 5.3e-167 troA P Belongs to the bacterial solute-binding protein 9 family
HEBFMCMF_03145 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HEBFMCMF_03146 3.2e-275 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HEBFMCMF_03147 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HEBFMCMF_03148 6.7e-153 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HEBFMCMF_03149 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HEBFMCMF_03150 1.9e-272 menF 5.4.4.2 HQ Isochorismate synthase
HEBFMCMF_03151 2.6e-132 dksA T COG1734 DnaK suppressor protein
HEBFMCMF_03152 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
HEBFMCMF_03153 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HEBFMCMF_03154 9.7e-180 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
HEBFMCMF_03155 6.3e-232 ytcC M Glycosyltransferase Family 4
HEBFMCMF_03157 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
HEBFMCMF_03158 1.8e-217 cotSA M Glycosyl transferases group 1
HEBFMCMF_03159 9.7e-205 cotI S Spore coat protein
HEBFMCMF_03160 4.5e-40 tspO T membrane
HEBFMCMF_03161 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HEBFMCMF_03162 4.3e-288 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
HEBFMCMF_03163 2.9e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
HEBFMCMF_03164 5.2e-196 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HEBFMCMF_03165 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HEBFMCMF_03174 7.8e-08
HEBFMCMF_03175 1.3e-09
HEBFMCMF_03182 2e-08
HEBFMCMF_03187 3.4e-39 S COG NOG14552 non supervised orthologous group
HEBFMCMF_03188 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
HEBFMCMF_03189 3.4e-94 M1-753 M FR47-like protein
HEBFMCMF_03190 3.5e-187 yuaG 3.4.21.72 S protein conserved in bacteria
HEBFMCMF_03191 1.2e-75 yuaF OU Membrane protein implicated in regulation of membrane protease activity
HEBFMCMF_03192 3.9e-84 yuaE S DinB superfamily
HEBFMCMF_03193 2.3e-107 yuaD
HEBFMCMF_03194 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
HEBFMCMF_03195 8e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
HEBFMCMF_03196 3.6e-94 yuaC K Belongs to the GbsR family
HEBFMCMF_03197 2.8e-91 yuaB
HEBFMCMF_03198 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
HEBFMCMF_03199 1.6e-236 ktrB P Potassium
HEBFMCMF_03200 1e-38 yiaA S yiaA/B two helix domain
HEBFMCMF_03201 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HEBFMCMF_03202 2.4e-273 yubD P Major Facilitator Superfamily
HEBFMCMF_03203 1.3e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
HEBFMCMF_03205 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HEBFMCMF_03206 1.3e-194 yubA S transporter activity
HEBFMCMF_03207 3.3e-183 ygjR S Oxidoreductase
HEBFMCMF_03208 6.7e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
HEBFMCMF_03209 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
HEBFMCMF_03210 5.1e-273 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HEBFMCMF_03211 6.6e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
HEBFMCMF_03212 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
HEBFMCMF_03213 7.3e-238 mcpA NT chemotaxis protein
HEBFMCMF_03214 4.7e-293 mcpA NT chemotaxis protein
HEBFMCMF_03215 2.4e-220 mcpA NT chemotaxis protein
HEBFMCMF_03216 3.2e-225 mcpA NT chemotaxis protein
HEBFMCMF_03217 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
HEBFMCMF_03218 2.3e-35
HEBFMCMF_03219 1.8e-71 yugU S Uncharacterised protein family UPF0047
HEBFMCMF_03220 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
HEBFMCMF_03221 8.4e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
HEBFMCMF_03222 1.4e-116 yugP S Zn-dependent protease
HEBFMCMF_03223 2.3e-38
HEBFMCMF_03224 5.4e-53 mstX S Membrane-integrating protein Mistic
HEBFMCMF_03225 8.2e-182 yugO P COG1226 Kef-type K transport systems
HEBFMCMF_03226 1.3e-72 yugN S YugN-like family
HEBFMCMF_03228 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
HEBFMCMF_03229 1.1e-228 yugK C Dehydrogenase
HEBFMCMF_03230 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
HEBFMCMF_03231 1.1e-34 yuzA S Domain of unknown function (DUF378)
HEBFMCMF_03232 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
HEBFMCMF_03233 5.3e-198 yugH 2.6.1.1 E Aminotransferase
HEBFMCMF_03234 1.6e-85 alaR K Transcriptional regulator
HEBFMCMF_03235 4.9e-156 yugF I Hydrolase
HEBFMCMF_03236 1.6e-39 yugE S Domain of unknown function (DUF1871)
HEBFMCMF_03237 2.9e-226 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HEBFMCMF_03238 6e-233 T PhoQ Sensor
HEBFMCMF_03239 3.3e-70 kapB G Kinase associated protein B
HEBFMCMF_03240 4.2e-115 kapD L the KinA pathway to sporulation
HEBFMCMF_03242 3.8e-185 yuxJ EGP Major facilitator Superfamily
HEBFMCMF_03243 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
HEBFMCMF_03244 1.8e-74 yuxK S protein conserved in bacteria
HEBFMCMF_03245 6.3e-78 yufK S Family of unknown function (DUF5366)
HEBFMCMF_03246 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HEBFMCMF_03247 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
HEBFMCMF_03248 2.5e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HEBFMCMF_03249 5.4e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HEBFMCMF_03250 2.5e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
HEBFMCMF_03251 2.9e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
HEBFMCMF_03252 1.3e-233 maeN C COG3493 Na citrate symporter
HEBFMCMF_03253 3.2e-14
HEBFMCMF_03254 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HEBFMCMF_03255 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEBFMCMF_03256 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEBFMCMF_03257 2.1e-261 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEBFMCMF_03258 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEBFMCMF_03259 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEBFMCMF_03260 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
HEBFMCMF_03261 1.8e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
HEBFMCMF_03262 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEBFMCMF_03263 0.0 comP 2.7.13.3 T Histidine kinase
HEBFMCMF_03265 2.1e-161 comQ H Polyprenyl synthetase
HEBFMCMF_03267 1.1e-22 yuzC
HEBFMCMF_03268 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
HEBFMCMF_03269 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HEBFMCMF_03270 1.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
HEBFMCMF_03271 7.9e-67 yueI S Protein of unknown function (DUF1694)
HEBFMCMF_03272 7.4e-39 yueH S YueH-like protein
HEBFMCMF_03273 1.7e-31 yueG S Spore germination protein gerPA/gerPF
HEBFMCMF_03274 1.2e-189 yueF S transporter activity
HEBFMCMF_03275 5.2e-71 S Protein of unknown function (DUF2283)
HEBFMCMF_03276 2.9e-24 S Protein of unknown function (DUF2642)
HEBFMCMF_03277 4.8e-96 yueE S phosphohydrolase
HEBFMCMF_03278 1.7e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEBFMCMF_03279 3.3e-64 yueC S Family of unknown function (DUF5383)
HEBFMCMF_03280 0.0 esaA S type VII secretion protein EsaA
HEBFMCMF_03281 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HEBFMCMF_03282 2.3e-211 essB S WXG100 protein secretion system (Wss), protein YukC
HEBFMCMF_03283 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
HEBFMCMF_03284 2.8e-45 esxA S Belongs to the WXG100 family
HEBFMCMF_03285 6.5e-229 yukF QT Transcriptional regulator
HEBFMCMF_03286 6.1e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
HEBFMCMF_03287 1.2e-131 yukJ S Uncharacterized conserved protein (DUF2278)
HEBFMCMF_03288 1.4e-35 mbtH S MbtH-like protein
HEBFMCMF_03289 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEBFMCMF_03290 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
HEBFMCMF_03291 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
HEBFMCMF_03292 2.1e-224 entC 5.4.4.2 HQ Isochorismate synthase
HEBFMCMF_03293 3.6e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HEBFMCMF_03294 1.5e-166 besA S Putative esterase
HEBFMCMF_03295 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
HEBFMCMF_03296 5.7e-93 bioY S Biotin biosynthesis protein
HEBFMCMF_03297 3.9e-211 yuiF S antiporter
HEBFMCMF_03298 3.4e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HEBFMCMF_03299 1.2e-77 yuiD S protein conserved in bacteria
HEBFMCMF_03300 1.4e-116 yuiC S protein conserved in bacteria
HEBFMCMF_03301 8.4e-27 yuiB S Putative membrane protein
HEBFMCMF_03302 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
HEBFMCMF_03303 3.9e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
HEBFMCMF_03305 6e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HEBFMCMF_03306 1.6e-114 paiB K Putative FMN-binding domain
HEBFMCMF_03307 6.1e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEBFMCMF_03308 3.7e-63 erpA S Belongs to the HesB IscA family
HEBFMCMF_03309 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HEBFMCMF_03310 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HEBFMCMF_03311 3.2e-39 yuzB S Belongs to the UPF0349 family
HEBFMCMF_03312 4.5e-199 yutJ 1.6.99.3 C NADH dehydrogenase
HEBFMCMF_03313 3.5e-57 yuzD S protein conserved in bacteria
HEBFMCMF_03314 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
HEBFMCMF_03315 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
HEBFMCMF_03316 6.2e-171 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HEBFMCMF_03317 7.5e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HEBFMCMF_03318 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
HEBFMCMF_03319 2.9e-198 yutH S Spore coat protein
HEBFMCMF_03320 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HEBFMCMF_03321 1.4e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HEBFMCMF_03322 8.6e-75 yutE S Protein of unknown function DUF86
HEBFMCMF_03323 9.7e-48 yutD S protein conserved in bacteria
HEBFMCMF_03324 2.7e-109 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HEBFMCMF_03325 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HEBFMCMF_03326 4.5e-196 lytH M Peptidase, M23
HEBFMCMF_03327 8.4e-134 yunB S Sporulation protein YunB (Spo_YunB)
HEBFMCMF_03328 3.1e-47 yunC S Domain of unknown function (DUF1805)
HEBFMCMF_03329 9.2e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HEBFMCMF_03330 1.3e-140 yunE S membrane transporter protein
HEBFMCMF_03331 4.3e-171 yunF S Protein of unknown function DUF72
HEBFMCMF_03332 6.3e-60 yunG
HEBFMCMF_03333 6.2e-257 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HEBFMCMF_03334 6.4e-301 pucR QT COG2508 Regulator of polyketide synthase expression
HEBFMCMF_03335 1.2e-231 pbuX F Permease family
HEBFMCMF_03336 3.7e-222 pbuX F xanthine
HEBFMCMF_03337 1.7e-82 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HEBFMCMF_03338 7.3e-183 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HEBFMCMF_03339 2.1e-55 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HEBFMCMF_03340 2.1e-96 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HEBFMCMF_03341 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HEBFMCMF_03342 1.4e-145 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HEBFMCMF_03343 1.2e-109 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
HEBFMCMF_03344 4.1e-189 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HEBFMCMF_03346 2.3e-237 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HEBFMCMF_03347 1e-237 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HEBFMCMF_03348 3.1e-169 bsn L Ribonuclease
HEBFMCMF_03349 1.2e-205 msmX P Belongs to the ABC transporter superfamily
HEBFMCMF_03350 5.6e-135 yurK K UTRA
HEBFMCMF_03351 8.2e-162 yurL 2.7.1.218 G pfkB family carbohydrate kinase
HEBFMCMF_03352 8.1e-168 yurM P COG0395 ABC-type sugar transport system, permease component
HEBFMCMF_03353 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
HEBFMCMF_03354 5.5e-239 yurO G COG1653 ABC-type sugar transport system, periplasmic component
HEBFMCMF_03355 2.6e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HEBFMCMF_03356 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
HEBFMCMF_03357 6.4e-207 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
HEBFMCMF_03359 1.5e-40
HEBFMCMF_03360 2.4e-65 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEBFMCMF_03361 3.5e-271 sufB O FeS cluster assembly
HEBFMCMF_03362 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
HEBFMCMF_03363 1.2e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HEBFMCMF_03364 1.4e-245 sufD O assembly protein SufD
HEBFMCMF_03365 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HEBFMCMF_03366 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HEBFMCMF_03367 4.2e-147 metQ P Belongs to the NlpA lipoprotein family
HEBFMCMF_03368 3e-95 metI P COG2011 ABC-type metal ion transport system, permease component
HEBFMCMF_03369 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HEBFMCMF_03370 3.2e-56 yusD S SCP-2 sterol transfer family
HEBFMCMF_03371 9.5e-55 traF CO Thioredoxin
HEBFMCMF_03372 1.6e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
HEBFMCMF_03373 1.1e-39 yusG S Protein of unknown function (DUF2553)
HEBFMCMF_03374 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HEBFMCMF_03375 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
HEBFMCMF_03376 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
HEBFMCMF_03377 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
HEBFMCMF_03378 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
HEBFMCMF_03379 8.1e-09 S YuzL-like protein
HEBFMCMF_03380 1.9e-164 fadM E Proline dehydrogenase
HEBFMCMF_03381 5.1e-40
HEBFMCMF_03382 5.4e-53 yusN M Coat F domain
HEBFMCMF_03383 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
HEBFMCMF_03384 9.4e-292 yusP P Major facilitator superfamily
HEBFMCMF_03385 2.7e-64 yusQ S Tautomerase enzyme
HEBFMCMF_03386 2.2e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HEBFMCMF_03387 3.7e-157 yusT K LysR substrate binding domain
HEBFMCMF_03388 3.8e-47 yusU S Protein of unknown function (DUF2573)
HEBFMCMF_03389 1e-153 yusV 3.6.3.34 HP ABC transporter
HEBFMCMF_03390 2.5e-66 S YusW-like protein
HEBFMCMF_03391 1.4e-301 pepF2 E COG1164 Oligoendopeptidase F
HEBFMCMF_03392 2.4e-150 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HEBFMCMF_03393 1.2e-79 dps P Ferritin-like domain
HEBFMCMF_03394 3.1e-235 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEBFMCMF_03395 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEBFMCMF_03396 2.4e-248 cssS 2.7.13.3 T PhoQ Sensor
HEBFMCMF_03397 2.1e-157 yuxN K Transcriptional regulator
HEBFMCMF_03398 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HEBFMCMF_03399 2.3e-24 S Protein of unknown function (DUF3970)
HEBFMCMF_03400 3.7e-247 gerAA EG Spore germination protein
HEBFMCMF_03401 9.1e-198 gerAB E Spore germination protein
HEBFMCMF_03402 4.6e-189 gerAC S Spore germination B3/ GerAC like, C-terminal
HEBFMCMF_03403 1.3e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEBFMCMF_03404 3.5e-186 vraS 2.7.13.3 T Histidine kinase
HEBFMCMF_03405 9.5e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
HEBFMCMF_03406 9.3e-129 liaG S Putative adhesin
HEBFMCMF_03407 2.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HEBFMCMF_03408 5.6e-62 liaI S membrane
HEBFMCMF_03409 2.4e-226 yvqJ EGP Major facilitator Superfamily
HEBFMCMF_03410 6.5e-102 yvqK 2.5.1.17 S Adenosyltransferase
HEBFMCMF_03411 6e-244 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HEBFMCMF_03412 2.7e-183 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEBFMCMF_03413 1.6e-166 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HEBFMCMF_03414 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HEBFMCMF_03415 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
HEBFMCMF_03416 0.0 T PhoQ Sensor
HEBFMCMF_03417 3.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEBFMCMF_03418 3.6e-22
HEBFMCMF_03419 1.6e-97 yvrI K RNA polymerase
HEBFMCMF_03420 2.4e-19 S YvrJ protein family
HEBFMCMF_03421 7.3e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
HEBFMCMF_03422 1.3e-64 yvrL S Regulatory protein YrvL
HEBFMCMF_03423 4.1e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
HEBFMCMF_03424 1.6e-123 macB V ABC transporter, ATP-binding protein
HEBFMCMF_03425 6.9e-175 M Efflux transporter rnd family, mfp subunit
HEBFMCMF_03426 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
HEBFMCMF_03427 1.5e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEBFMCMF_03428 4.6e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEBFMCMF_03429 1.2e-177 fhuD P ABC transporter
HEBFMCMF_03431 4.9e-236 yvsH E Arginine ornithine antiporter
HEBFMCMF_03432 6.5e-16 S Small spore protein J (Spore_SspJ)
HEBFMCMF_03433 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
HEBFMCMF_03434 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HEBFMCMF_03435 1.1e-167 yvgK P COG1910 Periplasmic molybdate-binding protein domain
HEBFMCMF_03436 4.9e-137 modA P COG0725 ABC-type molybdate transport system, periplasmic component
HEBFMCMF_03437 3.1e-119 modB P COG4149 ABC-type molybdate transport system, permease component
HEBFMCMF_03438 5.9e-157 yvgN S reductase
HEBFMCMF_03439 2.1e-85 yvgO
HEBFMCMF_03440 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
HEBFMCMF_03441 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HEBFMCMF_03442 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HEBFMCMF_03443 0.0 helD 3.6.4.12 L DNA helicase
HEBFMCMF_03445 2.7e-106 yvgT S membrane
HEBFMCMF_03446 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
HEBFMCMF_03447 1.6e-104 bdbD O Thioredoxin
HEBFMCMF_03448 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HEBFMCMF_03449 0.0 copA 3.6.3.54 P P-type ATPase
HEBFMCMF_03450 5.9e-29 copZ P Copper resistance protein CopZ
HEBFMCMF_03451 2.2e-48 csoR S transcriptional
HEBFMCMF_03452 6.9e-195 yvaA 1.1.1.371 S Oxidoreductase
HEBFMCMF_03453 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HEBFMCMF_03454 0.0 yvaC S Fusaric acid resistance protein-like
HEBFMCMF_03455 9.1e-71 yvaD S Family of unknown function (DUF5360)
HEBFMCMF_03456 2.8e-55 yvaE P Small Multidrug Resistance protein
HEBFMCMF_03457 4.1e-101 K Bacterial regulatory proteins, tetR family
HEBFMCMF_03458 7.7e-130 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HEBFMCMF_03460 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HEBFMCMF_03461 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HEBFMCMF_03462 5.6e-143 est 3.1.1.1 S Carboxylesterase
HEBFMCMF_03463 2.4e-23 secG U Preprotein translocase subunit SecG
HEBFMCMF_03464 8.2e-153 yvaM S Serine aminopeptidase, S33
HEBFMCMF_03465 9.8e-36 yvzC K Transcriptional
HEBFMCMF_03466 4e-69 K transcriptional
HEBFMCMF_03467 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
HEBFMCMF_03468 2.2e-54 yodB K transcriptional
HEBFMCMF_03469 3.6e-222 NT chemotaxis protein
HEBFMCMF_03470 5.2e-111 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HEBFMCMF_03471 1.2e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HEBFMCMF_03472 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HEBFMCMF_03473 1.2e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HEBFMCMF_03474 8.7e-61 yvbF K Belongs to the GbsR family
HEBFMCMF_03475 7.9e-13 S Sporulation delaying protein SdpA
HEBFMCMF_03476 4.9e-171
HEBFMCMF_03477 4.4e-08
HEBFMCMF_03478 3.1e-94 sdpI S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HEBFMCMF_03479 4.5e-45 sdpR K transcriptional
HEBFMCMF_03480 8.7e-114 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HEBFMCMF_03481 9.4e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HEBFMCMF_03482 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HEBFMCMF_03483 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HEBFMCMF_03484 1.4e-98 yvbF K Belongs to the GbsR family
HEBFMCMF_03485 6.4e-103 yvbG U UPF0056 membrane protein
HEBFMCMF_03486 8.6e-113 yvbH S YvbH-like oligomerisation region
HEBFMCMF_03487 1e-122 exoY M Membrane
HEBFMCMF_03488 9e-251 tcaA S response to antibiotic
HEBFMCMF_03489 1.7e-81 yvbK 3.1.3.25 K acetyltransferase
HEBFMCMF_03490 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HEBFMCMF_03491 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
HEBFMCMF_03492 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HEBFMCMF_03493 3.8e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HEBFMCMF_03494 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HEBFMCMF_03495 2.6e-183 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HEBFMCMF_03496 1.6e-252 araE EGP Major facilitator Superfamily
HEBFMCMF_03497 5.5e-203 araR K transcriptional
HEBFMCMF_03498 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEBFMCMF_03499 8.7e-159 yvbU K Transcriptional regulator
HEBFMCMF_03500 1.2e-155 yvbV EG EamA-like transporter family
HEBFMCMF_03501 3.7e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
HEBFMCMF_03502 3.6e-196 yvbX S Glycosyl hydrolase
HEBFMCMF_03503 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HEBFMCMF_03504 6e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HEBFMCMF_03505 6.5e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HEBFMCMF_03506 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEBFMCMF_03507 2e-200 desK 2.7.13.3 T Histidine kinase
HEBFMCMF_03508 1.4e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
HEBFMCMF_03509 4.4e-158 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
HEBFMCMF_03511 7.5e-157 rsbQ S Alpha/beta hydrolase family
HEBFMCMF_03512 2.2e-197 rsbU 3.1.3.3 T response regulator
HEBFMCMF_03513 6.6e-248 galA 3.2.1.89 G arabinogalactan
HEBFMCMF_03514 0.0 lacA 3.2.1.23 G beta-galactosidase
HEBFMCMF_03515 3.6e-149 ganQ P transport
HEBFMCMF_03516 1.1e-231 malC P COG1175 ABC-type sugar transport systems, permease components
HEBFMCMF_03517 7.5e-225 cycB G COG2182 Maltose-binding periplasmic proteins domains
HEBFMCMF_03518 1.8e-184 lacR K Transcriptional regulator
HEBFMCMF_03519 8.6e-112 yvfI K COG2186 Transcriptional regulators
HEBFMCMF_03520 4.8e-307 yvfH C L-lactate permease
HEBFMCMF_03521 3.3e-239 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HEBFMCMF_03522 1e-31 yvfG S YvfG protein
HEBFMCMF_03523 6.6e-184 yvfF GM Exopolysaccharide biosynthesis protein
HEBFMCMF_03524 5.3e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HEBFMCMF_03525 1e-55 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
HEBFMCMF_03526 5.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HEBFMCMF_03527 3.8e-255 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEBFMCMF_03528 9.8e-194 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
HEBFMCMF_03529 9.8e-205 epsI GM pyruvyl transferase
HEBFMCMF_03530 9.8e-194 epsH GT2 S Glycosyltransferase like family 2
HEBFMCMF_03531 7e-206 epsG S EpsG family
HEBFMCMF_03532 3.2e-217 epsF GT4 M Glycosyl transferases group 1
HEBFMCMF_03533 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HEBFMCMF_03534 1e-220 epsD GT4 M Glycosyl transferase 4-like
HEBFMCMF_03535 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
HEBFMCMF_03536 1.1e-113 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
HEBFMCMF_03537 4e-122 ywqC M biosynthesis protein
HEBFMCMF_03538 6.3e-76 slr K transcriptional
HEBFMCMF_03539 2.5e-283 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
HEBFMCMF_03541 1.7e-92 padC Q Phenolic acid decarboxylase
HEBFMCMF_03542 8.4e-73 MA20_18690 S Protein of unknown function (DUF3237)
HEBFMCMF_03543 1.1e-124 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HEBFMCMF_03544 3.2e-261 pbpE V Beta-lactamase
HEBFMCMF_03545 6.5e-273 sacB 2.4.1.10 GH68 M levansucrase activity
HEBFMCMF_03546 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HEBFMCMF_03547 1.8e-295 yveA E amino acid
HEBFMCMF_03548 2.6e-106 yvdT K Transcriptional regulator
HEBFMCMF_03549 6.7e-51 ykkC P Small Multidrug Resistance protein
HEBFMCMF_03550 4.1e-50 sugE P Small Multidrug Resistance protein
HEBFMCMF_03551 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
HEBFMCMF_03552 1.1e-269 ygaK C COG0277 FAD FMN-containing dehydrogenases
HEBFMCMF_03553 1.2e-182 S Patatin-like phospholipase
HEBFMCMF_03555 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HEBFMCMF_03556 6.8e-111 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
HEBFMCMF_03557 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
HEBFMCMF_03558 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
HEBFMCMF_03559 4.7e-152 malA S Protein of unknown function (DUF1189)
HEBFMCMF_03560 3.9e-148 malD P transport
HEBFMCMF_03561 5.9e-244 malC P COG1175 ABC-type sugar transport systems, permease components
HEBFMCMF_03562 2.8e-235 mdxE G COG2182 Maltose-binding periplasmic proteins domains
HEBFMCMF_03563 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
HEBFMCMF_03564 3.3e-172 yvdE K Transcriptional regulator
HEBFMCMF_03565 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
HEBFMCMF_03566 1.5e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
HEBFMCMF_03567 1.1e-287 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
HEBFMCMF_03568 4.8e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HEBFMCMF_03569 5.1e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEBFMCMF_03570 0.0 yxdM V ABC transporter (permease)
HEBFMCMF_03571 5.6e-141 yvcR V ABC transporter, ATP-binding protein
HEBFMCMF_03572 3.4e-197 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HEBFMCMF_03573 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEBFMCMF_03574 3.3e-32
HEBFMCMF_03575 4.9e-142 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
HEBFMCMF_03576 1.6e-36 crh G Phosphocarrier protein Chr
HEBFMCMF_03577 1.4e-170 whiA K May be required for sporulation
HEBFMCMF_03578 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HEBFMCMF_03579 5.7e-166 rapZ S Displays ATPase and GTPase activities
HEBFMCMF_03580 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HEBFMCMF_03581 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HEBFMCMF_03582 1.1e-97 usp CBM50 M protein conserved in bacteria
HEBFMCMF_03583 4.5e-277 S COG0457 FOG TPR repeat
HEBFMCMF_03584 0.0 msbA2 3.6.3.44 V ABC transporter
HEBFMCMF_03586 0.0
HEBFMCMF_03587 1.1e-74
HEBFMCMF_03588 7.6e-65
HEBFMCMF_03589 8.8e-113 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
HEBFMCMF_03590 8.1e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HEBFMCMF_03591 9.9e-132 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HEBFMCMF_03592 1.1e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HEBFMCMF_03593 5.1e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HEBFMCMF_03594 2.2e-227 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HEBFMCMF_03595 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HEBFMCMF_03596 1.5e-219 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HEBFMCMF_03597 3.8e-139 yvpB NU protein conserved in bacteria
HEBFMCMF_03598 5.1e-119 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
HEBFMCMF_03599 7.3e-81 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
HEBFMCMF_03600 1.2e-117 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HEBFMCMF_03601 1.1e-162 yvoD P COG0370 Fe2 transport system protein B
HEBFMCMF_03602 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HEBFMCMF_03603 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HEBFMCMF_03604 3.3e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HEBFMCMF_03605 9.2e-130 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HEBFMCMF_03606 8.9e-133 yvoA K transcriptional
HEBFMCMF_03607 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
HEBFMCMF_03608 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
HEBFMCMF_03609 5.3e-231 cypX 1.14.15.13 C Cytochrome P450
HEBFMCMF_03610 1.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
HEBFMCMF_03611 7.4e-86 yvmB K helix_turn_helix multiple antibiotic resistance protein
HEBFMCMF_03612 7.9e-203 yvmA EGP Major facilitator Superfamily
HEBFMCMF_03613 1.2e-50 yvlD S Membrane
HEBFMCMF_03614 2.6e-26 pspB KT PspC domain
HEBFMCMF_03615 3.4e-168 yvlB S Putative adhesin
HEBFMCMF_03616 8e-49 yvlA
HEBFMCMF_03617 5.7e-33 yvkN
HEBFMCMF_03618 4.6e-77 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HEBFMCMF_03619 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HEBFMCMF_03620 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HEBFMCMF_03621 1.2e-30 csbA S protein conserved in bacteria
HEBFMCMF_03622 0.0 yvkC 2.7.9.2 GT Phosphotransferase
HEBFMCMF_03623 1.3e-99 yvkB K Transcriptional regulator
HEBFMCMF_03624 3.6e-225 yvkA EGP Major facilitator Superfamily
HEBFMCMF_03625 1.9e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEBFMCMF_03626 5.3e-56 swrA S Swarming motility protein
HEBFMCMF_03627 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
HEBFMCMF_03628 2.1e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HEBFMCMF_03629 1.6e-123 ftsE D cell division ATP-binding protein FtsE
HEBFMCMF_03630 8.5e-54 cccB C COG2010 Cytochrome c, mono- and diheme variants
HEBFMCMF_03631 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
HEBFMCMF_03632 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HEBFMCMF_03633 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HEBFMCMF_03634 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HEBFMCMF_03635 2.8e-66
HEBFMCMF_03636 1.9e-08 fliT S bacterial-type flagellum organization
HEBFMCMF_03637 3.2e-68 fliS N flagellar protein FliS
HEBFMCMF_03638 1.3e-266 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HEBFMCMF_03639 6.1e-57 flaG N flagellar protein FlaG
HEBFMCMF_03640 1.9e-156 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HEBFMCMF_03641 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HEBFMCMF_03642 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HEBFMCMF_03643 2.6e-50 yviE
HEBFMCMF_03644 1.1e-156 flgL N Belongs to the bacterial flagellin family
HEBFMCMF_03645 1.2e-264 flgK N flagellar hook-associated protein
HEBFMCMF_03646 2.4e-78 flgN NOU FlgN protein
HEBFMCMF_03647 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
HEBFMCMF_03648 7e-74 yvyF S flagellar protein
HEBFMCMF_03649 2.7e-129 comFC S Phosphoribosyl transferase domain
HEBFMCMF_03650 5.7e-46 comFB S Late competence development protein ComFB
HEBFMCMF_03651 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HEBFMCMF_03652 7.3e-155 degV S protein conserved in bacteria
HEBFMCMF_03653 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEBFMCMF_03654 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HEBFMCMF_03655 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
HEBFMCMF_03656 6e-163 yvhJ K Transcriptional regulator
HEBFMCMF_03657 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HEBFMCMF_03658 2.7e-235 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
HEBFMCMF_03659 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
HEBFMCMF_03660 1.5e-113 tuaF M protein involved in exopolysaccharide biosynthesis
HEBFMCMF_03661 1.8e-262 tuaE M Teichuronic acid biosynthesis protein
HEBFMCMF_03662 2e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HEBFMCMF_03663 1.1e-217 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
HEBFMCMF_03664 8.2e-247 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEBFMCMF_03665 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HEBFMCMF_03666 2.8e-93 M Glycosyltransferase like family 2
HEBFMCMF_03667 9.1e-209 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HEBFMCMF_03668 0.0 lytB 3.5.1.28 D Stage II sporulation protein
HEBFMCMF_03669 1e-11
HEBFMCMF_03670 5.9e-158 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HEBFMCMF_03671 1.6e-216 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HEBFMCMF_03672 2.1e-88 M Glycosyltransferase like family 2
HEBFMCMF_03673 1.6e-99 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HEBFMCMF_03674 3.7e-23 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HEBFMCMF_03675 4.5e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HEBFMCMF_03676 2.8e-272 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HEBFMCMF_03677 2.9e-132 tagG GM Transport permease protein
HEBFMCMF_03678 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HEBFMCMF_03679 9e-240 ggaA M Glycosyltransferase like family 2
HEBFMCMF_03680 1.1e-135 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HEBFMCMF_03681 2.1e-56 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
HEBFMCMF_03682 7.1e-88 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HEBFMCMF_03683 2.3e-94 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HEBFMCMF_03684 1e-104 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HEBFMCMF_03685 6.2e-148 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HEBFMCMF_03686 2.5e-89 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HEBFMCMF_03687 2.5e-192 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HEBFMCMF_03688 3e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HEBFMCMF_03689 2.3e-189 pmi 5.3.1.8 G mannose-6-phosphate isomerase
HEBFMCMF_03690 3.5e-266 gerBA EG Spore germination protein
HEBFMCMF_03691 1.7e-199 gerBB E Spore germination protein
HEBFMCMF_03692 1.6e-210 gerAC S Spore germination protein
HEBFMCMF_03693 2e-247 ywtG EGP Major facilitator Superfamily
HEBFMCMF_03694 3.2e-170 ywtF K Transcriptional regulator
HEBFMCMF_03695 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
HEBFMCMF_03696 4.5e-239 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HEBFMCMF_03697 1.4e-20 ywtC
HEBFMCMF_03698 1.1e-217 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HEBFMCMF_03699 8.6e-70 pgsC S biosynthesis protein
HEBFMCMF_03700 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
HEBFMCMF_03701 1.2e-177 rbsR K transcriptional
HEBFMCMF_03702 5.5e-161 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEBFMCMF_03703 3.1e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HEBFMCMF_03704 8.6e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HEBFMCMF_03705 5.5e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
HEBFMCMF_03706 2.4e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
HEBFMCMF_03707 1e-93 batE T Sh3 type 3 domain protein
HEBFMCMF_03708 8e-48 ywsA S Protein of unknown function (DUF3892)
HEBFMCMF_03709 9.7e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
HEBFMCMF_03710 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
HEBFMCMF_03711 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HEBFMCMF_03712 1.1e-169 alsR K LysR substrate binding domain
HEBFMCMF_03713 4.6e-219 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HEBFMCMF_03714 7.5e-126 ywrJ
HEBFMCMF_03715 2.9e-130 cotB
HEBFMCMF_03716 3.5e-210 cotH M Spore Coat
HEBFMCMF_03717 3.7e-12
HEBFMCMF_03718 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HEBFMCMF_03719 5e-54 S Domain of unknown function (DUF4181)
HEBFMCMF_03720 4.7e-304 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HEBFMCMF_03721 8e-82 ywrC K Transcriptional regulator
HEBFMCMF_03722 1.2e-103 ywrB P Chromate transporter
HEBFMCMF_03723 9.9e-89 ywrA P COG2059 Chromate transport protein ChrA
HEBFMCMF_03725 8.2e-99 ywqN S NAD(P)H-dependent
HEBFMCMF_03726 4.9e-162 K Transcriptional regulator
HEBFMCMF_03727 6.7e-117 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HEBFMCMF_03728 3.9e-25
HEBFMCMF_03729 3.5e-242 ywqJ S Pre-toxin TG
HEBFMCMF_03730 2.5e-37 ywqI S Family of unknown function (DUF5344)
HEBFMCMF_03731 9.7e-23 S Domain of unknown function (DUF5082)
HEBFMCMF_03732 6.6e-150 ywqG S Domain of unknown function (DUF1963)
HEBFMCMF_03733 3.7e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HEBFMCMF_03734 3e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
HEBFMCMF_03735 2.9e-120 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
HEBFMCMF_03736 5.9e-116 ywqC M biosynthesis protein
HEBFMCMF_03737 1.2e-17
HEBFMCMF_03738 2.1e-307 ywqB S SWIM zinc finger
HEBFMCMF_03739 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HEBFMCMF_03740 3.9e-156 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
HEBFMCMF_03741 5.7e-138 glcR K COG1349 Transcriptional regulators of sugar metabolism
HEBFMCMF_03742 3.7e-57 ssbB L Single-stranded DNA-binding protein
HEBFMCMF_03743 1.4e-65 ywpG
HEBFMCMF_03744 2.4e-66 ywpF S YwpF-like protein
HEBFMCMF_03745 8.7e-84 srtA 3.4.22.70 M Sortase family
HEBFMCMF_03746 0.0 M1-568 M cell wall anchor domain
HEBFMCMF_03747 0.0 M1-568 M cell wall anchor domain
HEBFMCMF_03748 9e-174 M1-574 T Transcriptional regulatory protein, C terminal
HEBFMCMF_03749 0.0 ywpD T PhoQ Sensor
HEBFMCMF_03750 1.5e-49 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HEBFMCMF_03751 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HEBFMCMF_03752 8.8e-198 S aspartate phosphatase
HEBFMCMF_03753 8.3e-140 flhP N flagellar basal body
HEBFMCMF_03754 3.4e-125 flhO N flagellar basal body
HEBFMCMF_03755 3.5e-180 mbl D Rod shape-determining protein
HEBFMCMF_03756 3e-44 spoIIID K Stage III sporulation protein D
HEBFMCMF_03757 2.1e-70 ywoH K COG1846 Transcriptional regulators
HEBFMCMF_03758 2.7e-211 ywoG EGP Major facilitator Superfamily
HEBFMCMF_03759 1.6e-231 ywoF P Right handed beta helix region
HEBFMCMF_03760 3e-281 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
HEBFMCMF_03761 3.5e-239 ywoD EGP Major facilitator superfamily
HEBFMCMF_03762 6.8e-104 phzA Q Isochorismatase family
HEBFMCMF_03763 8.3e-76
HEBFMCMF_03764 4.3e-225 amt P Ammonium transporter
HEBFMCMF_03765 1.6e-58 nrgB K Belongs to the P(II) protein family
HEBFMCMF_03766 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
HEBFMCMF_03767 3.9e-123 2.1.1.72 L DNA methylase
HEBFMCMF_03768 1.4e-18 K Helix-turn-helix XRE-family like proteins
HEBFMCMF_03769 3.6e-32 L Restriction endonuclease BamHI
HEBFMCMF_03770 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
HEBFMCMF_03771 6.4e-90 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
HEBFMCMF_03772 7.7e-14 ywnC S Family of unknown function (DUF5362)
HEBFMCMF_03773 2.9e-70 ywnF S Family of unknown function (DUF5392)
HEBFMCMF_03774 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEBFMCMF_03775 2.9e-142 mta K transcriptional
HEBFMCMF_03776 2.6e-59 ywnC S Family of unknown function (DUF5362)
HEBFMCMF_03777 1.7e-111 ywnB S NAD(P)H-binding
HEBFMCMF_03778 1.7e-64 ywnA K Transcriptional regulator
HEBFMCMF_03779 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HEBFMCMF_03780 1.7e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HEBFMCMF_03781 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HEBFMCMF_03783 3.2e-10 csbD K CsbD-like
HEBFMCMF_03784 3e-84 ywmF S Peptidase M50
HEBFMCMF_03785 7.9e-104 S response regulator aspartate phosphatase
HEBFMCMF_03786 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HEBFMCMF_03787 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HEBFMCMF_03789 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
HEBFMCMF_03790 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
HEBFMCMF_03791 3.9e-174 spoIID D Stage II sporulation protein D
HEBFMCMF_03792 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEBFMCMF_03793 2.9e-131 ywmB S TATA-box binding
HEBFMCMF_03794 1.3e-32 ywzB S membrane
HEBFMCMF_03795 4.3e-88 ywmA
HEBFMCMF_03796 8.5e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HEBFMCMF_03797 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HEBFMCMF_03798 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HEBFMCMF_03799 1.7e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HEBFMCMF_03800 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEBFMCMF_03801 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HEBFMCMF_03802 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEBFMCMF_03803 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
HEBFMCMF_03804 1.6e-61 atpI S ATP synthase
HEBFMCMF_03805 3e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HEBFMCMF_03806 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HEBFMCMF_03807 1.6e-94 ywlG S Belongs to the UPF0340 family
HEBFMCMF_03808 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
HEBFMCMF_03809 1.9e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HEBFMCMF_03810 1.7e-91 mntP P Probably functions as a manganese efflux pump
HEBFMCMF_03811 5.2e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HEBFMCMF_03812 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
HEBFMCMF_03813 6.1e-112 spoIIR S stage II sporulation protein R
HEBFMCMF_03814 4.8e-55 ywlA S Uncharacterised protein family (UPF0715)
HEBFMCMF_03816 2.6e-155 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HEBFMCMF_03817 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HEBFMCMF_03818 1.2e-67 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEBFMCMF_03819 7.1e-90 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HEBFMCMF_03820 8.6e-160 ywkB S Membrane transport protein
HEBFMCMF_03821 0.0 sfcA 1.1.1.38 C malic enzyme
HEBFMCMF_03822 7e-104 tdk 2.7.1.21 F thymidine kinase
HEBFMCMF_03823 1.1e-32 rpmE J Binds the 23S rRNA
HEBFMCMF_03824 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HEBFMCMF_03825 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
HEBFMCMF_03826 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEBFMCMF_03827 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HEBFMCMF_03828 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
HEBFMCMF_03829 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
HEBFMCMF_03830 7.9e-91 ywjG S Domain of unknown function (DUF2529)
HEBFMCMF_03831 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HEBFMCMF_03832 1.5e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HEBFMCMF_03833 6.3e-210 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
HEBFMCMF_03834 0.0 fadF C COG0247 Fe-S oxidoreductase
HEBFMCMF_03835 2.3e-223 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HEBFMCMF_03836 6.6e-184 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HEBFMCMF_03837 2.7e-42 ywjC
HEBFMCMF_03838 2.4e-95 ywjB H RibD C-terminal domain
HEBFMCMF_03839 0.0 ywjA V ABC transporter
HEBFMCMF_03840 2.4e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEBFMCMF_03841 3.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
HEBFMCMF_03842 3.6e-94 narJ 1.7.5.1 C nitrate reductase
HEBFMCMF_03843 9.7e-296 narH 1.7.5.1 C Nitrate reductase, beta
HEBFMCMF_03844 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEBFMCMF_03845 7e-86 arfM T cyclic nucleotide binding
HEBFMCMF_03846 1.7e-139 ywiC S YwiC-like protein
HEBFMCMF_03847 2.6e-129 fnr K helix_turn_helix, cAMP Regulatory protein
HEBFMCMF_03848 2.3e-213 narK P COG2223 Nitrate nitrite transporter
HEBFMCMF_03849 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HEBFMCMF_03850 4.7e-73 ywiB S protein conserved in bacteria
HEBFMCMF_03851 1e-07 S Bacteriocin subtilosin A
HEBFMCMF_03852 4.9e-270 C Fe-S oxidoreductases
HEBFMCMF_03854 1.3e-131 cbiO V ABC transporter
HEBFMCMF_03855 7.2e-234 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
HEBFMCMF_03856 4.2e-217 2.7.1.26, 2.7.7.2 L Peptidase, M16
HEBFMCMF_03857 4.3e-247 L Peptidase, M16
HEBFMCMF_03859 2.5e-245 ywhL CO amine dehydrogenase activity
HEBFMCMF_03860 2.7e-191 ywhK CO amine dehydrogenase activity
HEBFMCMF_03861 8.9e-79 S aspartate phosphatase
HEBFMCMF_03863 3.7e-28 ywhH S Aminoacyl-tRNA editing domain
HEBFMCMF_03864 2.7e-168 speB 3.5.3.11 E Belongs to the arginase family
HEBFMCMF_03865 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HEBFMCMF_03866 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HEBFMCMF_03867 2e-94 ywhD S YwhD family
HEBFMCMF_03868 5.1e-119 ywhC S Peptidase family M50
HEBFMCMF_03869 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
HEBFMCMF_03870 9.5e-71 ywhA K Transcriptional regulator
HEBFMCMF_03871 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HEBFMCMF_03873 3.9e-238 mmr U Major Facilitator Superfamily
HEBFMCMF_03874 3.4e-77 yffB K Transcriptional regulator
HEBFMCMF_03875 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
HEBFMCMF_03876 5.1e-256 ywfO S COG1078 HD superfamily phosphohydrolases
HEBFMCMF_03877 3.1e-36 ywzC S Belongs to the UPF0741 family
HEBFMCMF_03878 3.9e-110 rsfA_1
HEBFMCMF_03879 9.8e-158 ywfM EG EamA-like transporter family
HEBFMCMF_03880 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HEBFMCMF_03881 3.4e-158 cysL K Transcriptional regulator
HEBFMCMF_03882 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
HEBFMCMF_03883 1.1e-146 ywfI C May function as heme-dependent peroxidase
HEBFMCMF_03884 8.3e-137 IQ Enoyl-(Acyl carrier protein) reductase
HEBFMCMF_03885 5.6e-233 ywfG 2.6.1.83 E Aminotransferase class I and II
HEBFMCMF_03886 1.9e-209 bacE EGP Major facilitator Superfamily
HEBFMCMF_03887 6.1e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HEBFMCMF_03888 3.3e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEBFMCMF_03889 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HEBFMCMF_03890 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HEBFMCMF_03891 3e-205 ywfA EGP Major facilitator Superfamily
HEBFMCMF_03892 7.4e-250 lysP E amino acid
HEBFMCMF_03893 0.0 rocB E arginine degradation protein
HEBFMCMF_03894 5.1e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HEBFMCMF_03895 1.3e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HEBFMCMF_03896 1.2e-77
HEBFMCMF_03897 3.5e-87 spsL 5.1.3.13 M Spore Coat
HEBFMCMF_03898 1.5e-160 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HEBFMCMF_03899 1.5e-180 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HEBFMCMF_03900 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HEBFMCMF_03901 1.1e-186 spsG M Spore Coat
HEBFMCMF_03902 5.3e-130 spsF M Spore Coat
HEBFMCMF_03903 6e-213 spsE 2.5.1.56 M acid synthase
HEBFMCMF_03904 6.4e-162 spsD 2.3.1.210 K Spore Coat
HEBFMCMF_03905 7.9e-224 spsC E Belongs to the DegT DnrJ EryC1 family
HEBFMCMF_03906 2.1e-268 spsB M Capsule polysaccharide biosynthesis protein
HEBFMCMF_03907 1.8e-144 spsA M Spore Coat
HEBFMCMF_03908 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HEBFMCMF_03909 4.3e-59 ywdK S small membrane protein
HEBFMCMF_03910 8.3e-238 ywdJ F Xanthine uracil
HEBFMCMF_03911 5e-48 ywdI S Family of unknown function (DUF5327)
HEBFMCMF_03912 2.7e-260 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HEBFMCMF_03913 1.1e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HEBFMCMF_03914 5.5e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
HEBFMCMF_03916 1.7e-111 ywdD
HEBFMCMF_03917 1.3e-57 pex K Transcriptional regulator PadR-like family
HEBFMCMF_03918 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HEBFMCMF_03919 2e-28 ywdA
HEBFMCMF_03920 3e-289 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
HEBFMCMF_03921 4.7e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HEBFMCMF_03922 2.6e-138 focA P Formate/nitrite transporter
HEBFMCMF_03923 7e-150 sacT K transcriptional antiterminator
HEBFMCMF_03925 0.0 vpr O Belongs to the peptidase S8 family
HEBFMCMF_03926 3.3e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEBFMCMF_03927 6.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
HEBFMCMF_03928 8.6e-202 rodA D Belongs to the SEDS family
HEBFMCMF_03929 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
HEBFMCMF_03930 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HEBFMCMF_03931 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HEBFMCMF_03932 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HEBFMCMF_03933 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HEBFMCMF_03934 1e-35 ywzA S membrane
HEBFMCMF_03935 3.1e-300 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HEBFMCMF_03936 1.4e-228 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HEBFMCMF_03937 9.5e-60 gtcA S GtrA-like protein
HEBFMCMF_03938 1.1e-121 ywcC K transcriptional regulator
HEBFMCMF_03940 9.8e-49 ywcB S Protein of unknown function, DUF485
HEBFMCMF_03941 3.1e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEBFMCMF_03942 9.3e-112 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HEBFMCMF_03943 7.1e-223 ywbN P Dyp-type peroxidase family protein
HEBFMCMF_03944 5.5e-185 ycdO P periplasmic lipoprotein involved in iron transport
HEBFMCMF_03945 3.8e-252 P COG0672 High-affinity Fe2 Pb2 permease
HEBFMCMF_03946 1.4e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HEBFMCMF_03947 8.2e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HEBFMCMF_03948 1.6e-152 ywbI K Transcriptional regulator
HEBFMCMF_03949 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HEBFMCMF_03950 2.3e-111 ywbG M effector of murein hydrolase
HEBFMCMF_03951 3.1e-207 ywbF EGP Major facilitator Superfamily
HEBFMCMF_03952 1.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
HEBFMCMF_03953 3.5e-219 ywbD 2.1.1.191 J Methyltransferase
HEBFMCMF_03954 9.9e-67 ywbC 4.4.1.5 E glyoxalase
HEBFMCMF_03955 6.1e-241 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEBFMCMF_03956 1.9e-264 epr 3.4.21.62 O Belongs to the peptidase S8 family
HEBFMCMF_03957 7.6e-242 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HEBFMCMF_03958 3.4e-152 sacY K transcriptional antiterminator
HEBFMCMF_03959 2.9e-167 gspA M General stress
HEBFMCMF_03960 3.7e-123 ywaF S Integral membrane protein
HEBFMCMF_03961 2.3e-87 ywaE K Transcriptional regulator
HEBFMCMF_03962 3.7e-232 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HEBFMCMF_03963 5.7e-250 ywaD 3.4.11.10, 3.4.11.6 S PA domain
HEBFMCMF_03964 1.4e-92 K Helix-turn-helix XRE-family like proteins
HEBFMCMF_03965 4.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
HEBFMCMF_03966 1.3e-35 ynfM EGP Major facilitator Superfamily
HEBFMCMF_03967 3.3e-82 ynfM EGP Major facilitator Superfamily
HEBFMCMF_03968 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
HEBFMCMF_03969 1.5e-164 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HEBFMCMF_03970 5e-14 S D-Ala-teichoic acid biosynthesis protein
HEBFMCMF_03971 6.7e-292 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEBFMCMF_03972 1.4e-231 dltB M membrane protein involved in D-alanine export
HEBFMCMF_03973 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEBFMCMF_03974 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HEBFMCMF_03975 1.2e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
HEBFMCMF_03976 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HEBFMCMF_03977 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HEBFMCMF_03978 2.5e-50 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
HEBFMCMF_03979 2.8e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEBFMCMF_03980 5.2e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
HEBFMCMF_03981 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
HEBFMCMF_03982 1.1e-19 yxzF
HEBFMCMF_03983 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HEBFMCMF_03984 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HEBFMCMF_03985 2.6e-44 yxlH EGP Major facilitator Superfamily
HEBFMCMF_03986 2.9e-157 yxlH EGP Major facilitator Superfamily
HEBFMCMF_03987 1.8e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HEBFMCMF_03988 7e-164 yxlF V ABC transporter, ATP-binding protein
HEBFMCMF_03989 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
HEBFMCMF_03990 1.4e-30
HEBFMCMF_03991 3.9e-48 yxlC S Family of unknown function (DUF5345)
HEBFMCMF_03992 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
HEBFMCMF_03993 5.6e-253 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
HEBFMCMF_03994 1.2e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HEBFMCMF_03995 0.0 cydD V ATP-binding protein
HEBFMCMF_03996 0.0 cydD V ATP-binding
HEBFMCMF_03997 8.4e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
HEBFMCMF_03998 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
HEBFMCMF_03999 1.5e-229 cimH C COG3493 Na citrate symporter
HEBFMCMF_04000 3.5e-310 3.4.24.84 O Peptidase family M48
HEBFMCMF_04002 4.3e-155 yxkH G Polysaccharide deacetylase
HEBFMCMF_04003 2.2e-204 msmK P Belongs to the ABC transporter superfamily
HEBFMCMF_04004 2e-163 lrp QT PucR C-terminal helix-turn-helix domain
HEBFMCMF_04005 4.8e-271 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HEBFMCMF_04006 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HEBFMCMF_04007 1.4e-73 yxkC S Domain of unknown function (DUF4352)
HEBFMCMF_04008 6.7e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HEBFMCMF_04009 3.4e-77 S Protein of unknown function (DUF1453)
HEBFMCMF_04010 8.3e-192 yxjM T Signal transduction histidine kinase
HEBFMCMF_04011 7.1e-113 K helix_turn_helix, Lux Regulon
HEBFMCMF_04012 1.4e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HEBFMCMF_04015 7.1e-86 yxjI S LURP-one-related
HEBFMCMF_04016 6.7e-220 yxjG 2.1.1.14 E Methionine synthase
HEBFMCMF_04017 8.2e-218 yxjG 2.1.1.14 E Methionine synthase
HEBFMCMF_04018 2.4e-136 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HEBFMCMF_04019 1.2e-115 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HEBFMCMF_04020 6.9e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HEBFMCMF_04021 1.3e-249 yxjC EG COG2610 H gluconate symporter and related permeases
HEBFMCMF_04022 8.5e-142 rlmA 2.1.1.187 Q Methyltransferase domain
HEBFMCMF_04023 4.1e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HEBFMCMF_04024 4e-103 T Domain of unknown function (DUF4163)
HEBFMCMF_04025 3e-47 yxiS
HEBFMCMF_04026 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
HEBFMCMF_04027 6.6e-224 citH C Citrate transporter
HEBFMCMF_04028 3.3e-143 exoK GH16 M licheninase activity
HEBFMCMF_04029 8.3e-151 licT K transcriptional antiterminator
HEBFMCMF_04030 2.2e-109
HEBFMCMF_04031 2.5e-231 yxiO S COG2270 Permeases of the major facilitator superfamily
HEBFMCMF_04032 3.3e-264 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HEBFMCMF_04033 1.2e-216 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
HEBFMCMF_04034 3.3e-53 padR K Transcriptional regulator PadR-like family
HEBFMCMF_04035 6.5e-61 S Protein of unknown function (DUF2812)
HEBFMCMF_04038 2e-43 yxiJ S YxiJ-like protein
HEBFMCMF_04039 3.7e-82 yxiI S Protein of unknown function (DUF2716)
HEBFMCMF_04040 1.1e-162 yxxF EG EamA-like transporter family
HEBFMCMF_04041 8.2e-126 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEBFMCMF_04042 7.8e-121 1.14.11.45 E 2OG-Fe dioxygenase
HEBFMCMF_04043 9.2e-72 yxiE T Belongs to the universal stress protein A family
HEBFMCMF_04044 4.5e-277 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HEBFMCMF_04045 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HEBFMCMF_04046 5.5e-53
HEBFMCMF_04047 3.3e-47
HEBFMCMF_04048 1.2e-267 S nuclease activity
HEBFMCMF_04049 1.4e-38 yxiC S Family of unknown function (DUF5344)
HEBFMCMF_04050 5.1e-20 S Domain of unknown function (DUF5082)
HEBFMCMF_04051 6.7e-278 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HEBFMCMF_04052 9.4e-10 S Oxidoreductase
HEBFMCMF_04054 4.2e-13 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
HEBFMCMF_04055 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HEBFMCMF_04056 3.1e-281 hutH 4.3.1.3 E Histidine ammonia-lyase
HEBFMCMF_04057 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HEBFMCMF_04058 3.1e-234 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
HEBFMCMF_04059 2e-180 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HEBFMCMF_04060 3.4e-250 lysP E amino acid
HEBFMCMF_04061 3.6e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
HEBFMCMF_04062 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HEBFMCMF_04063 7.7e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HEBFMCMF_04064 2.3e-173 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HEBFMCMF_04065 2e-152 yxxB S Domain of Unknown Function (DUF1206)
HEBFMCMF_04066 3.7e-199 eutH E Ethanolamine utilisation protein, EutH
HEBFMCMF_04067 4.7e-249 yxeQ S MmgE/PrpD family
HEBFMCMF_04068 3e-212 yxeP 3.5.1.47 E hydrolase activity
HEBFMCMF_04069 7.7e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
HEBFMCMF_04070 3.5e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
HEBFMCMF_04071 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
HEBFMCMF_04072 1.4e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEBFMCMF_04073 2.8e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEBFMCMF_04074 3.2e-186 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HEBFMCMF_04075 1.4e-150 yidA S hydrolases of the HAD superfamily
HEBFMCMF_04078 1.3e-20 yxeE
HEBFMCMF_04079 5.6e-16 yxeD
HEBFMCMF_04080 1.4e-68
HEBFMCMF_04081 1.9e-175 fhuD P ABC transporter
HEBFMCMF_04082 1.5e-58 yxeA S Protein of unknown function (DUF1093)
HEBFMCMF_04083 0.0 yxdM V ABC transporter (permease)
HEBFMCMF_04084 9.4e-141 yxdL V ABC transporter, ATP-binding protein
HEBFMCMF_04085 4.8e-182 T PhoQ Sensor
HEBFMCMF_04086 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEBFMCMF_04087 1.2e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HEBFMCMF_04088 2.1e-138 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HEBFMCMF_04089 8.6e-167 iolH G Xylose isomerase-like TIM barrel
HEBFMCMF_04090 6.1e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HEBFMCMF_04091 1.6e-233 iolF EGP Major facilitator Superfamily
HEBFMCMF_04092 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HEBFMCMF_04093 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HEBFMCMF_04094 7.1e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HEBFMCMF_04095 1.1e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HEBFMCMF_04096 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HEBFMCMF_04097 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
HEBFMCMF_04098 8.3e-176 iolS C Aldo keto reductase
HEBFMCMF_04100 1.9e-47 yxcD S Protein of unknown function (DUF2653)
HEBFMCMF_04101 2.8e-244 csbC EGP Major facilitator Superfamily
HEBFMCMF_04102 0.0 htpG O Molecular chaperone. Has ATPase activity
HEBFMCMF_04104 2.4e-150 IQ Enoyl-(Acyl carrier protein) reductase
HEBFMCMF_04105 2.7e-208 yxbF K Bacterial regulatory proteins, tetR family
HEBFMCMF_04106 1.3e-246 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HEBFMCMF_04107 1.4e-30 yxaI S membrane protein domain
HEBFMCMF_04108 1.2e-76 S PQQ-like domain
HEBFMCMF_04109 4.3e-63 S Family of unknown function (DUF5391)
HEBFMCMF_04110 1.4e-75 yxaI S membrane protein domain
HEBFMCMF_04111 4.3e-225 P Protein of unknown function (DUF418)
HEBFMCMF_04112 6.4e-198 yxaG 1.13.11.24 S AraC-like ligand binding domain
HEBFMCMF_04113 7.1e-101 yxaF K Transcriptional regulator
HEBFMCMF_04114 3.1e-198 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HEBFMCMF_04115 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
HEBFMCMF_04116 8.9e-50 S LrgA family
HEBFMCMF_04117 2.6e-118 yxaC M effector of murein hydrolase
HEBFMCMF_04118 3.1e-192 yxaB GM Polysaccharide pyruvyl transferase
HEBFMCMF_04119 1.2e-205 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HEBFMCMF_04120 7.3e-127 gntR K transcriptional
HEBFMCMF_04121 1.2e-301 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
HEBFMCMF_04122 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
HEBFMCMF_04123 5e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HEBFMCMF_04124 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
HEBFMCMF_04125 1.9e-286 ahpF O Alkyl hydroperoxide reductase
HEBFMCMF_04126 5.6e-189 wgaE S Polysaccharide pyruvyl transferase
HEBFMCMF_04127 7.8e-290 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HEBFMCMF_04128 2e-18 bglF G phosphotransferase system
HEBFMCMF_04129 1e-125 yydK K Transcriptional regulator
HEBFMCMF_04130 3.8e-12
HEBFMCMF_04131 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
HEBFMCMF_04133 2.7e-118 mobC K Transcriptional regulator
HEBFMCMF_04134 5.1e-293 D Protein of unknown function (DUF3732)
HEBFMCMF_04135 3.6e-11
HEBFMCMF_04136 6e-99
HEBFMCMF_04137 1.5e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HEBFMCMF_04138 1.1e-09 S YyzF-like protein
HEBFMCMF_04139 6.7e-61
HEBFMCMF_04140 8.7e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HEBFMCMF_04142 4.1e-29 yycQ S Protein of unknown function (DUF2651)
HEBFMCMF_04143 2.1e-205 yycP
HEBFMCMF_04144 1.3e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HEBFMCMF_04145 2.2e-84 yycN 2.3.1.128 K Acetyltransferase
HEBFMCMF_04146 8.5e-188 S aspartate phosphatase
HEBFMCMF_04148 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
HEBFMCMF_04149 1.3e-260 rocE E amino acid
HEBFMCMF_04150 4.3e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
HEBFMCMF_04151 2.6e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HEBFMCMF_04152 4.6e-173 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
HEBFMCMF_04153 3.4e-94 K PFAM response regulator receiver
HEBFMCMF_04154 2.6e-73 S Peptidase propeptide and YPEB domain
HEBFMCMF_04155 1.9e-33 S Peptidase propeptide and YPEB domain
HEBFMCMF_04156 8.7e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEBFMCMF_04157 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HEBFMCMF_04158 6.2e-154 yycI S protein conserved in bacteria
HEBFMCMF_04159 7.5e-258 yycH S protein conserved in bacteria
HEBFMCMF_04160 0.0 vicK 2.7.13.3 T Histidine kinase
HEBFMCMF_04161 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEBFMCMF_04166 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HEBFMCMF_04167 4.4e-76 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEBFMCMF_04168 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HEBFMCMF_04169 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
HEBFMCMF_04171 1.9e-15 yycC K YycC-like protein
HEBFMCMF_04172 1.2e-219 yeaN P COG2807 Cyanate permease
HEBFMCMF_04173 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HEBFMCMF_04174 2.2e-73 rplI J binds to the 23S rRNA
HEBFMCMF_04175 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HEBFMCMF_04176 8.3e-160 yybS S membrane
HEBFMCMF_04178 3.3e-83 cotF M Spore coat protein
HEBFMCMF_04179 1.7e-66 ydeP3 K Transcriptional regulator
HEBFMCMF_04180 8.1e-163 ppaC 3.6.1.1 C Inorganic pyrophosphatase
HEBFMCMF_04181 3.6e-60
HEBFMCMF_04183 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
HEBFMCMF_04184 2.2e-110 K TipAS antibiotic-recognition domain
HEBFMCMF_04185 2.8e-124
HEBFMCMF_04186 2.8e-64 yybH S SnoaL-like domain
HEBFMCMF_04187 7.4e-123 yybG S Pentapeptide repeat-containing protein
HEBFMCMF_04188 1.8e-215 ynfM EGP Major facilitator Superfamily
HEBFMCMF_04189 4e-164 yybE K Transcriptional regulator
HEBFMCMF_04190 7.7e-79 yjcF S Acetyltransferase (GNAT) domain
HEBFMCMF_04191 1.6e-74 yybC
HEBFMCMF_04192 6.6e-127 S Metallo-beta-lactamase superfamily
HEBFMCMF_04193 5.6e-77 yybA 2.3.1.57 K transcriptional
HEBFMCMF_04194 2e-71 yjcF S Acetyltransferase (GNAT) domain
HEBFMCMF_04195 5.5e-96 yyaS S Membrane
HEBFMCMF_04196 1.6e-91 yyaR K Acetyltransferase (GNAT) domain
HEBFMCMF_04197 1.3e-65 yyaQ S YjbR
HEBFMCMF_04198 2.1e-105 yyaP 1.5.1.3 H RibD C-terminal domain
HEBFMCMF_04199 6.6e-246 tetL EGP Major facilitator Superfamily
HEBFMCMF_04200 2.3e-29 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HEBFMCMF_04202 4.1e-11 S Putative amidase domain
HEBFMCMF_04203 5.1e-61 yyaN K MerR HTH family regulatory protein
HEBFMCMF_04204 2.8e-160 yyaM EG EamA-like transporter family
HEBFMCMF_04205 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HEBFMCMF_04206 8e-168 yyaK S CAAX protease self-immunity
HEBFMCMF_04207 3.2e-245 EGP Major facilitator superfamily
HEBFMCMF_04208 1.1e-93 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
HEBFMCMF_04209 1.4e-65 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEBFMCMF_04210 1.2e-179 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
HEBFMCMF_04211 4e-144 xth 3.1.11.2 L exodeoxyribonuclease III
HEBFMCMF_04212 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HEBFMCMF_04213 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HEBFMCMF_04214 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
HEBFMCMF_04215 3.4e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HEBFMCMF_04216 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEBFMCMF_04217 2.3e-33 yyzM S protein conserved in bacteria
HEBFMCMF_04218 8.1e-177 yyaD S Membrane
HEBFMCMF_04219 2.8e-111 yyaC S Sporulation protein YyaC
HEBFMCMF_04220 1.3e-148 spo0J K Belongs to the ParB family
HEBFMCMF_04221 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
HEBFMCMF_04222 9.6e-74 S Bacterial PH domain
HEBFMCMF_04223 5.5e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HEBFMCMF_04224 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HEBFMCMF_04225 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HEBFMCMF_04226 8.3e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HEBFMCMF_04227 6.5e-108 jag S single-stranded nucleic acid binding R3H
HEBFMCMF_04228 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HEBFMCMF_04229 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)