ORF_ID e_value Gene_name EC_number CAZy COGs Description
MIOPJFLD_00001 1.3e-235 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MIOPJFLD_00002 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MIOPJFLD_00003 2.4e-33 yaaA S S4 domain
MIOPJFLD_00004 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MIOPJFLD_00005 1.8e-37 yaaB S Domain of unknown function (DUF370)
MIOPJFLD_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MIOPJFLD_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MIOPJFLD_00008 3.4e-39 S COG NOG14552 non supervised orthologous group
MIOPJFLD_00011 2.5e-180 yaaC S YaaC-like Protein
MIOPJFLD_00012 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MIOPJFLD_00013 6.8e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MIOPJFLD_00014 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MIOPJFLD_00015 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MIOPJFLD_00016 8.1e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MIOPJFLD_00017 1.3e-09
MIOPJFLD_00018 8.3e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
MIOPJFLD_00019 7.9e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
MIOPJFLD_00020 2.4e-213 yaaH M Glycoside Hydrolase Family
MIOPJFLD_00021 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
MIOPJFLD_00022 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MIOPJFLD_00023 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MIOPJFLD_00024 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MIOPJFLD_00025 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MIOPJFLD_00026 7.9e-32 yaaL S Protein of unknown function (DUF2508)
MIOPJFLD_00027 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
MIOPJFLD_00028 3.4e-39 S COG NOG14552 non supervised orthologous group
MIOPJFLD_00031 2.2e-30 csfB S Inhibitor of sigma-G Gin
MIOPJFLD_00032 3.4e-101 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
MIOPJFLD_00033 2.2e-202 yaaN P Belongs to the TelA family
MIOPJFLD_00034 8.7e-273 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
MIOPJFLD_00035 1.2e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MIOPJFLD_00036 2.2e-54 yaaQ S protein conserved in bacteria
MIOPJFLD_00037 1.5e-71 yaaR S protein conserved in bacteria
MIOPJFLD_00038 1.1e-181 holB 2.7.7.7 L DNA polymerase III
MIOPJFLD_00039 6.1e-146 yaaT S stage 0 sporulation protein
MIOPJFLD_00040 4.8e-31 yabA L Involved in initiation control of chromosome replication
MIOPJFLD_00041 5.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
MIOPJFLD_00042 1.5e-49 yazA L endonuclease containing a URI domain
MIOPJFLD_00043 4.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MIOPJFLD_00044 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
MIOPJFLD_00045 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MIOPJFLD_00046 1.2e-143 tatD L hydrolase, TatD
MIOPJFLD_00047 2e-167 rpfB GH23 T protein conserved in bacteria
MIOPJFLD_00048 3e-96 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MIOPJFLD_00049 6.9e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MIOPJFLD_00050 2.8e-136 yabG S peptidase
MIOPJFLD_00051 7.8e-39 veg S protein conserved in bacteria
MIOPJFLD_00052 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MIOPJFLD_00053 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
MIOPJFLD_00054 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
MIOPJFLD_00055 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MIOPJFLD_00056 9.5e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MIOPJFLD_00057 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MIOPJFLD_00058 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MIOPJFLD_00059 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MIOPJFLD_00060 2.4e-39 yabK S Peptide ABC transporter permease
MIOPJFLD_00061 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MIOPJFLD_00062 1.5e-92 spoVT K stage V sporulation protein
MIOPJFLD_00063 9.3e-284 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MIOPJFLD_00064 2.5e-243 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MIOPJFLD_00065 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MIOPJFLD_00066 1.5e-49 yabP S Sporulation protein YabP
MIOPJFLD_00067 9.5e-107 yabQ S spore cortex biosynthesis protein
MIOPJFLD_00068 3.6e-45 divIC D Septum formation initiator
MIOPJFLD_00069 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
MIOPJFLD_00072 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
MIOPJFLD_00073 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
MIOPJFLD_00074 3.7e-185 KLT serine threonine protein kinase
MIOPJFLD_00075 6.1e-271 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MIOPJFLD_00076 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MIOPJFLD_00077 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MIOPJFLD_00078 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MIOPJFLD_00079 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MIOPJFLD_00080 4.4e-158 yacD 5.2.1.8 O peptidyl-prolyl isomerase
MIOPJFLD_00081 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MIOPJFLD_00082 9.1e-267 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MIOPJFLD_00083 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
MIOPJFLD_00084 8.7e-167 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
MIOPJFLD_00085 1.7e-159 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MIOPJFLD_00086 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MIOPJFLD_00087 7.9e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MIOPJFLD_00088 4.1e-30 yazB K transcriptional
MIOPJFLD_00089 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MIOPJFLD_00090 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MIOPJFLD_00091 3.4e-39 S COG NOG14552 non supervised orthologous group
MIOPJFLD_00096 2e-08
MIOPJFLD_00101 3.4e-39 S COG NOG14552 non supervised orthologous group
MIOPJFLD_00102 2.9e-76 ctsR K Belongs to the CtsR family
MIOPJFLD_00103 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
MIOPJFLD_00104 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MIOPJFLD_00105 0.0 clpC O Belongs to the ClpA ClpB family
MIOPJFLD_00106 9.6e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MIOPJFLD_00107 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MIOPJFLD_00108 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
MIOPJFLD_00109 7.2e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MIOPJFLD_00110 3.5e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MIOPJFLD_00111 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MIOPJFLD_00112 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
MIOPJFLD_00113 5.5e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MIOPJFLD_00114 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MIOPJFLD_00115 9.8e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MIOPJFLD_00116 1.2e-88 yacP S RNA-binding protein containing a PIN domain
MIOPJFLD_00117 4.4e-115 sigH K Belongs to the sigma-70 factor family
MIOPJFLD_00118 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MIOPJFLD_00119 4.9e-96 nusG K Participates in transcription elongation, termination and antitermination
MIOPJFLD_00120 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MIOPJFLD_00121 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MIOPJFLD_00122 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MIOPJFLD_00123 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MIOPJFLD_00124 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
MIOPJFLD_00125 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MIOPJFLD_00126 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MIOPJFLD_00127 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
MIOPJFLD_00128 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MIOPJFLD_00129 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MIOPJFLD_00130 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MIOPJFLD_00131 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MIOPJFLD_00132 3.7e-179 ybaC 3.4.11.5 S Alpha/beta hydrolase family
MIOPJFLD_00133 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
MIOPJFLD_00134 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MIOPJFLD_00135 3.9e-105 rplD J Forms part of the polypeptide exit tunnel
MIOPJFLD_00136 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MIOPJFLD_00137 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MIOPJFLD_00138 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MIOPJFLD_00139 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MIOPJFLD_00140 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MIOPJFLD_00141 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MIOPJFLD_00142 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
MIOPJFLD_00143 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MIOPJFLD_00144 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MIOPJFLD_00145 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MIOPJFLD_00146 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MIOPJFLD_00147 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MIOPJFLD_00148 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MIOPJFLD_00149 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MIOPJFLD_00150 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MIOPJFLD_00151 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MIOPJFLD_00152 1.9e-23 rpmD J Ribosomal protein L30
MIOPJFLD_00153 1.8e-72 rplO J binds to the 23S rRNA
MIOPJFLD_00154 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MIOPJFLD_00155 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MIOPJFLD_00156 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
MIOPJFLD_00157 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MIOPJFLD_00158 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MIOPJFLD_00159 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MIOPJFLD_00160 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MIOPJFLD_00161 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MIOPJFLD_00162 3.6e-58 rplQ J Ribosomal protein L17
MIOPJFLD_00163 1.9e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MIOPJFLD_00164 3.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MIOPJFLD_00165 1e-118 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MIOPJFLD_00166 2.6e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MIOPJFLD_00167 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MIOPJFLD_00168 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
MIOPJFLD_00169 9e-144 ybaJ Q Methyltransferase domain
MIOPJFLD_00170 9.7e-66 ybaK S Protein of unknown function (DUF2521)
MIOPJFLD_00171 1.9e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MIOPJFLD_00172 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MIOPJFLD_00173 1.2e-84 gerD
MIOPJFLD_00174 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
MIOPJFLD_00175 1e-139 pdaB 3.5.1.104 G Polysaccharide deacetylase
MIOPJFLD_00176 3.4e-39 S COG NOG14552 non supervised orthologous group
MIOPJFLD_00179 2e-08
MIOPJFLD_00183 3.4e-39 S COG NOG14552 non supervised orthologous group
MIOPJFLD_00184 3.4e-39 S COG NOG14552 non supervised orthologous group
MIOPJFLD_00185 7.9e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
MIOPJFLD_00187 1.7e-160 ybaS 1.1.1.58 S Na -dependent transporter
MIOPJFLD_00188 1.2e-137 ybbA S Putative esterase
MIOPJFLD_00189 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIOPJFLD_00190 3.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIOPJFLD_00191 4e-165 feuA P Iron-uptake system-binding protein
MIOPJFLD_00192 2.8e-304 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
MIOPJFLD_00193 6e-238 ybbC 3.2.1.52 S protein conserved in bacteria
MIOPJFLD_00194 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
MIOPJFLD_00195 9.2e-253 yfeW 3.4.16.4 V Belongs to the UPF0214 family
MIOPJFLD_00196 6.4e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MIOPJFLD_00197 2.5e-150 ybbH K transcriptional
MIOPJFLD_00198 4.6e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MIOPJFLD_00199 3.5e-85 ybbJ J acetyltransferase
MIOPJFLD_00200 1.5e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
MIOPJFLD_00206 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
MIOPJFLD_00207 1.8e-102 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MIOPJFLD_00208 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MIOPJFLD_00209 2.6e-224 ybbR S protein conserved in bacteria
MIOPJFLD_00210 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MIOPJFLD_00211 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MIOPJFLD_00212 9.3e-172 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MIOPJFLD_00213 1.6e-114 adaA 3.2.2.21 K Transcriptional regulator
MIOPJFLD_00214 9e-98 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MIOPJFLD_00215 3.8e-271 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MIOPJFLD_00216 0.0 ybcC S Belongs to the UPF0753 family
MIOPJFLD_00217 3.6e-91 can 4.2.1.1 P carbonic anhydrase
MIOPJFLD_00218 8.7e-47
MIOPJFLD_00219 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
MIOPJFLD_00221 5.1e-50 ybzH K Helix-turn-helix domain
MIOPJFLD_00222 3.5e-203 ybcL EGP Major facilitator Superfamily
MIOPJFLD_00223 4.9e-57
MIOPJFLD_00225 1.1e-138 KLT Protein tyrosine kinase
MIOPJFLD_00226 5.5e-150 ybdN
MIOPJFLD_00227 3.7e-213 ybdO S Domain of unknown function (DUF4885)
MIOPJFLD_00228 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
MIOPJFLD_00229 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
MIOPJFLD_00230 4.9e-30 ybxH S Family of unknown function (DUF5370)
MIOPJFLD_00231 9.8e-149 ybxI 3.5.2.6 V beta-lactamase
MIOPJFLD_00232 7.8e-246 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
MIOPJFLD_00233 1.4e-40 ybyB
MIOPJFLD_00234 6.8e-290 ybeC E amino acid
MIOPJFLD_00235 1e-162 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MIOPJFLD_00236 7.3e-258 glpT G -transporter
MIOPJFLD_00237 1.5e-34 S Protein of unknown function (DUF2651)
MIOPJFLD_00238 2.8e-168 ybfA 3.4.15.5 K FR47-like protein
MIOPJFLD_00239 7.9e-222 ybfB G COG0477 Permeases of the major facilitator superfamily
MIOPJFLD_00241 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
MIOPJFLD_00242 3.7e-160 ybfH EG EamA-like transporter family
MIOPJFLD_00243 3.3e-144 msmR K AraC-like ligand binding domain
MIOPJFLD_00244 8e-148 draG 3.2.2.24 O ADP-ribosylglycohydrolase
MIOPJFLD_00245 1.8e-77 M nucleic acid phosphodiester bond hydrolysis
MIOPJFLD_00246 5.2e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MIOPJFLD_00247 5.8e-177 mpr 3.4.21.19 M Belongs to the peptidase S1B family
MIOPJFLD_00249 4.4e-166 S Alpha/beta hydrolase family
MIOPJFLD_00250 9.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MIOPJFLD_00251 2.7e-85 ybfM S SNARE associated Golgi protein
MIOPJFLD_00252 8.1e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
MIOPJFLD_00253 4.6e-45 ybfN
MIOPJFLD_00254 1.3e-249 S Erythromycin esterase
MIOPJFLD_00255 3.9e-192 yceA S Belongs to the UPF0176 family
MIOPJFLD_00256 6.4e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MIOPJFLD_00257 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MIOPJFLD_00258 9.1e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MIOPJFLD_00259 1.4e-127 K UTRA
MIOPJFLD_00260 4.5e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MIOPJFLD_00261 6.7e-262 mmuP E amino acid
MIOPJFLD_00262 6.7e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
MIOPJFLD_00263 2.5e-256 agcS E Sodium alanine symporter
MIOPJFLD_00264 3.8e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
MIOPJFLD_00265 4.2e-229 phoQ 2.7.13.3 T Histidine kinase
MIOPJFLD_00266 1.5e-169 glnL T Regulator
MIOPJFLD_00267 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
MIOPJFLD_00268 1.5e-272 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MIOPJFLD_00269 4.5e-255 gudP G COG0477 Permeases of the major facilitator superfamily
MIOPJFLD_00270 6.7e-267 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MIOPJFLD_00271 1.5e-124 ycbG K FCD
MIOPJFLD_00272 3.8e-295 garD 4.2.1.42, 4.2.1.7 G Altronate
MIOPJFLD_00273 2.6e-177 ycbJ S Macrolide 2'-phosphotransferase
MIOPJFLD_00274 5.7e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
MIOPJFLD_00275 3.4e-169 eamA1 EG spore germination
MIOPJFLD_00276 3.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MIOPJFLD_00277 3.2e-167 T PhoQ Sensor
MIOPJFLD_00278 5e-165 ycbN V ABC transporter, ATP-binding protein
MIOPJFLD_00279 5.1e-114 S ABC-2 family transporter protein
MIOPJFLD_00280 8.2e-53 ycbP S Protein of unknown function (DUF2512)
MIOPJFLD_00281 2.2e-78 sleB 3.5.1.28 M Cell wall
MIOPJFLD_00282 1.2e-134 ycbR T vWA found in TerF C terminus
MIOPJFLD_00283 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
MIOPJFLD_00284 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MIOPJFLD_00285 1.7e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MIOPJFLD_00286 6.5e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MIOPJFLD_00287 2.3e-204 ycbU E Selenocysteine lyase
MIOPJFLD_00288 7.9e-226 lmrB EGP the major facilitator superfamily
MIOPJFLD_00289 7e-101 yxaF K Transcriptional regulator
MIOPJFLD_00290 5.3e-201 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MIOPJFLD_00291 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
MIOPJFLD_00292 3.4e-59 S RDD family
MIOPJFLD_00293 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
MIOPJFLD_00294 6.8e-157 2.7.13.3 T GHKL domain
MIOPJFLD_00295 3.9e-125 lytR_2 T LytTr DNA-binding domain
MIOPJFLD_00296 1.2e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
MIOPJFLD_00297 4.6e-200 natB CP ABC-2 family transporter protein
MIOPJFLD_00298 8.6e-173 yccK C Aldo keto reductase
MIOPJFLD_00299 6.6e-177 ycdA S Domain of unknown function (DUF5105)
MIOPJFLD_00300 3.9e-278 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
MIOPJFLD_00301 5.1e-260 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
MIOPJFLD_00302 1.6e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
MIOPJFLD_00303 1.2e-173 S response regulator aspartate phosphatase
MIOPJFLD_00304 1e-139 IQ Enoyl-(Acyl carrier protein) reductase
MIOPJFLD_00305 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
MIOPJFLD_00306 1.2e-166 adcA P Belongs to the bacterial solute-binding protein 9 family
MIOPJFLD_00307 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MIOPJFLD_00308 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MIOPJFLD_00309 1.4e-184 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIOPJFLD_00310 5.1e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
MIOPJFLD_00311 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
MIOPJFLD_00312 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
MIOPJFLD_00313 1.4e-136 terC P Protein of unknown function (DUF475)
MIOPJFLD_00314 0.0 yceG S Putative component of 'biosynthetic module'
MIOPJFLD_00315 2e-192 yceH P Belongs to the TelA family
MIOPJFLD_00316 6.6e-218 naiP P Uncharacterised MFS-type transporter YbfB
MIOPJFLD_00317 5.7e-206 yceJ EGP Uncharacterised MFS-type transporter YbfB
MIOPJFLD_00318 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
MIOPJFLD_00319 5.1e-229 proV 3.6.3.32 E glycine betaine
MIOPJFLD_00320 1.3e-127 opuAB P glycine betaine
MIOPJFLD_00321 5.3e-164 opuAC E glycine betaine
MIOPJFLD_00322 4.1e-217 amhX S amidohydrolase
MIOPJFLD_00323 8.1e-255 ycgA S Membrane
MIOPJFLD_00324 4.1e-81 ycgB
MIOPJFLD_00325 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
MIOPJFLD_00326 9.5e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MIOPJFLD_00327 1.4e-292 lctP C L-lactate permease
MIOPJFLD_00328 3.9e-263 mdr EGP Major facilitator Superfamily
MIOPJFLD_00329 1.3e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
MIOPJFLD_00330 6.8e-113 ycgF E Lysine exporter protein LysE YggA
MIOPJFLD_00331 4.9e-150 yqcI S YqcI/YcgG family
MIOPJFLD_00332 1.4e-248 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
MIOPJFLD_00333 2.4e-112 ycgI S Domain of unknown function (DUF1989)
MIOPJFLD_00334 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MIOPJFLD_00335 4.7e-108 tmrB S AAA domain
MIOPJFLD_00336 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MIOPJFLD_00337 3.1e-144 yafE Q ubiE/COQ5 methyltransferase family
MIOPJFLD_00338 3.2e-178 oxyR3 K LysR substrate binding domain
MIOPJFLD_00339 4.2e-183 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
MIOPJFLD_00340 6.4e-145 ycgL S Predicted nucleotidyltransferase
MIOPJFLD_00341 5.1e-170 ycgM E Proline dehydrogenase
MIOPJFLD_00342 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
MIOPJFLD_00343 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MIOPJFLD_00344 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
MIOPJFLD_00345 2.2e-143 ycgQ S membrane
MIOPJFLD_00346 2e-139 ycgR S permeases
MIOPJFLD_00347 6.5e-159 I alpha/beta hydrolase fold
MIOPJFLD_00348 3e-187 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
MIOPJFLD_00349 6e-274 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
MIOPJFLD_00350 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
MIOPJFLD_00351 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MIOPJFLD_00352 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MIOPJFLD_00353 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
MIOPJFLD_00354 2.9e-221 nasA P COG2223 Nitrate nitrite transporter
MIOPJFLD_00355 6.7e-170 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
MIOPJFLD_00356 2e-106 yciB M ErfK YbiS YcfS YnhG
MIOPJFLD_00357 7e-228 yciC S GTPases (G3E family)
MIOPJFLD_00358 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
MIOPJFLD_00359 3.4e-131 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
MIOPJFLD_00361 9.6e-77 yckC S membrane
MIOPJFLD_00362 3.5e-52 yckD S Protein of unknown function (DUF2680)
MIOPJFLD_00363 6.1e-295 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MIOPJFLD_00364 1.7e-69 nin S Competence protein J (ComJ)
MIOPJFLD_00365 7.8e-71 nucA M Deoxyribonuclease NucA/NucB
MIOPJFLD_00366 1e-179 tlpC 2.7.13.3 NT chemotaxis protein
MIOPJFLD_00367 3.3e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
MIOPJFLD_00368 8e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
MIOPJFLD_00369 1.3e-63 hxlR K transcriptional
MIOPJFLD_00370 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MIOPJFLD_00371 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MIOPJFLD_00372 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
MIOPJFLD_00373 5.7e-140 srfAD Q thioesterase
MIOPJFLD_00374 2e-225 EGP Major Facilitator Superfamily
MIOPJFLD_00375 9.6e-87 S YcxB-like protein
MIOPJFLD_00376 2.9e-160 ycxC EG EamA-like transporter family
MIOPJFLD_00377 2.3e-251 ycxD K GntR family transcriptional regulator
MIOPJFLD_00378 1.5e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
MIOPJFLD_00379 1.7e-114 yczE S membrane
MIOPJFLD_00380 8.2e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MIOPJFLD_00381 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
MIOPJFLD_00382 2e-125 tcyA ET Belongs to the bacterial solute-binding protein 3 family
MIOPJFLD_00383 1.9e-161 bsdA K LysR substrate binding domain
MIOPJFLD_00384 3.7e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MIOPJFLD_00385 4.1e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
MIOPJFLD_00386 4e-39 bsdD 4.1.1.61 S response to toxic substance
MIOPJFLD_00387 3.5e-82 yclD
MIOPJFLD_00388 4.4e-160 yclE 3.4.11.5 S Alpha beta hydrolase
MIOPJFLD_00389 1.4e-262 dtpT E amino acid peptide transporter
MIOPJFLD_00390 2.5e-298 yclG M Pectate lyase superfamily protein
MIOPJFLD_00392 5.4e-279 gerKA EG Spore germination protein
MIOPJFLD_00393 1.4e-223 gerKC S spore germination
MIOPJFLD_00394 1.8e-193 gerKB F Spore germination protein
MIOPJFLD_00395 1.6e-120 yclH P ABC transporter
MIOPJFLD_00396 1.3e-202 yclI V ABC transporter (permease) YclI
MIOPJFLD_00397 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MIOPJFLD_00398 4.4e-261 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MIOPJFLD_00399 2e-70 S aspartate phosphatase
MIOPJFLD_00403 7.7e-239 lysC 2.7.2.4 E Belongs to the aspartokinase family
MIOPJFLD_00404 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIOPJFLD_00405 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIOPJFLD_00406 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
MIOPJFLD_00407 8.5e-168 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
MIOPJFLD_00408 3.2e-251 ycnB EGP Major facilitator Superfamily
MIOPJFLD_00409 4.2e-153 ycnC K Transcriptional regulator
MIOPJFLD_00410 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
MIOPJFLD_00411 2.8e-45 ycnE S Monooxygenase
MIOPJFLD_00412 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
MIOPJFLD_00413 5.1e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MIOPJFLD_00414 3.4e-244 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MIOPJFLD_00415 1.4e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MIOPJFLD_00416 6.1e-149 glcU U Glucose uptake
MIOPJFLD_00417 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIOPJFLD_00418 9.3e-99 ycnI S protein conserved in bacteria
MIOPJFLD_00419 3.9e-306 ycnJ P protein, homolog of Cu resistance protein CopC
MIOPJFLD_00420 3.3e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
MIOPJFLD_00421 2.6e-53
MIOPJFLD_00422 7.4e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
MIOPJFLD_00423 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
MIOPJFLD_00424 4e-209 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
MIOPJFLD_00425 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
MIOPJFLD_00426 2.1e-09 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MIOPJFLD_00427 1.7e-75 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MIOPJFLD_00428 2.8e-108 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
MIOPJFLD_00429 1.3e-66 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
MIOPJFLD_00431 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
MIOPJFLD_00432 6.7e-139 ycsF S Belongs to the UPF0271 (lamB) family
MIOPJFLD_00433 2.7e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
MIOPJFLD_00434 2.8e-148 ycsI S Belongs to the D-glutamate cyclase family
MIOPJFLD_00435 9.4e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
MIOPJFLD_00436 7.3e-186 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
MIOPJFLD_00437 2.7e-132 kipR K Transcriptional regulator
MIOPJFLD_00438 3e-116 ycsK E anatomical structure formation involved in morphogenesis
MIOPJFLD_00440 5.4e-49 yczJ S biosynthesis
MIOPJFLD_00441 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
MIOPJFLD_00442 3.4e-174 ydhF S Oxidoreductase
MIOPJFLD_00443 0.0 mtlR K transcriptional regulator, MtlR
MIOPJFLD_00444 8.7e-292 ydaB IQ acyl-CoA ligase
MIOPJFLD_00445 7.6e-98 ydaC Q Methyltransferase domain
MIOPJFLD_00446 3.1e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIOPJFLD_00447 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
MIOPJFLD_00448 4.7e-102 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MIOPJFLD_00449 6.8e-77 ydaG 1.4.3.5 S general stress protein
MIOPJFLD_00450 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
MIOPJFLD_00451 3.3e-46 ydzA EGP Major facilitator Superfamily
MIOPJFLD_00452 2.5e-74 lrpC K Transcriptional regulator
MIOPJFLD_00453 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MIOPJFLD_00454 3.1e-206 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
MIOPJFLD_00455 2.7e-149 ydaK T Diguanylate cyclase, GGDEF domain
MIOPJFLD_00456 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
MIOPJFLD_00457 4.5e-233 ydaM M Glycosyl transferase family group 2
MIOPJFLD_00458 0.0 ydaN S Bacterial cellulose synthase subunit
MIOPJFLD_00459 0.0 ydaO E amino acid
MIOPJFLD_00460 1.6e-76 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
MIOPJFLD_00461 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MIOPJFLD_00462 4.7e-39
MIOPJFLD_00463 5e-224 mntH P H( )-stimulated, divalent metal cation uptake system
MIOPJFLD_00465 2.8e-76 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
MIOPJFLD_00466 2.7e-146 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
MIOPJFLD_00468 8.9e-59 ydbB G Cupin domain
MIOPJFLD_00469 1.8e-62 ydbC S Domain of unknown function (DUF4937
MIOPJFLD_00470 1e-153 ydbD P Catalase
MIOPJFLD_00471 3.5e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MIOPJFLD_00472 4.8e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MIOPJFLD_00473 1.1e-119 dctR T COG4565 Response regulator of citrate malate metabolism
MIOPJFLD_00474 1.4e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MIOPJFLD_00475 9.7e-181 ydbI S AI-2E family transporter
MIOPJFLD_00476 8e-171 ydbJ V ABC transporter, ATP-binding protein
MIOPJFLD_00477 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MIOPJFLD_00478 2.7e-52 ydbL
MIOPJFLD_00479 3.4e-219 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
MIOPJFLD_00480 1.1e-18 S Fur-regulated basic protein B
MIOPJFLD_00481 2.2e-07 S Fur-regulated basic protein A
MIOPJFLD_00482 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MIOPJFLD_00483 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MIOPJFLD_00484 3.9e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MIOPJFLD_00485 2.3e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MIOPJFLD_00486 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MIOPJFLD_00487 2.1e-82 ydbS S Bacterial PH domain
MIOPJFLD_00488 3.7e-263 ydbT S Membrane
MIOPJFLD_00489 2.4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
MIOPJFLD_00490 2.1e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MIOPJFLD_00491 8.5e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
MIOPJFLD_00492 1.9e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MIOPJFLD_00493 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MIOPJFLD_00494 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
MIOPJFLD_00495 1.3e-143 rsbR T Positive regulator of sigma-B
MIOPJFLD_00496 5.2e-57 rsbS T antagonist
MIOPJFLD_00497 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MIOPJFLD_00498 7.1e-189 rsbU 3.1.3.3 KT phosphatase
MIOPJFLD_00499 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
MIOPJFLD_00500 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
MIOPJFLD_00501 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MIOPJFLD_00502 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
MIOPJFLD_00503 0.0 yhgF K COG2183 Transcriptional accessory protein
MIOPJFLD_00504 8.9e-83 ydcK S Belongs to the SprT family
MIOPJFLD_00512 2e-85 L Phage integrase family
MIOPJFLD_00513 9.4e-25 S Domain of unknown function with cystatin-like fold (DUF4467)
MIOPJFLD_00514 1.8e-156 3.6.4.12 L HELICc2
MIOPJFLD_00516 1.6e-50
MIOPJFLD_00517 8e-47 S SMI1-KNR4 cell-wall
MIOPJFLD_00518 1.6e-43
MIOPJFLD_00519 2.9e-142 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MIOPJFLD_00520 1.9e-69 L HNH nucleases
MIOPJFLD_00522 1.7e-32 K Helix-turn-helix XRE-family like proteins
MIOPJFLD_00523 4.6e-42
MIOPJFLD_00524 3.5e-191 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
MIOPJFLD_00525 8.7e-30 cspL K Cold shock
MIOPJFLD_00526 6.1e-79 carD K Transcription factor
MIOPJFLD_00527 1.4e-143 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MIOPJFLD_00528 1.2e-163 rhaS5 K AraC-like ligand binding domain
MIOPJFLD_00529 3.7e-171 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MIOPJFLD_00530 6.2e-165 ydeE K AraC family transcriptional regulator
MIOPJFLD_00531 2.8e-260 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MIOPJFLD_00532 4.6e-217 ydeG EGP Major facilitator superfamily
MIOPJFLD_00533 5.2e-44 ydeH
MIOPJFLD_00534 3.9e-102 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
MIOPJFLD_00535 4.4e-107
MIOPJFLD_00536 4.9e-15 ptsH G PTS HPr component phosphorylation site
MIOPJFLD_00537 4.3e-75 K Transcriptional regulator C-terminal region
MIOPJFLD_00538 5e-151 ydeK EG -transporter
MIOPJFLD_00539 2.1e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MIOPJFLD_00540 4.2e-74 maoC I N-terminal half of MaoC dehydratase
MIOPJFLD_00541 2.8e-105 ydeN S Serine hydrolase
MIOPJFLD_00542 1.5e-55 K HxlR-like helix-turn-helix
MIOPJFLD_00543 6e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
MIOPJFLD_00544 1.8e-68 ydeP K Transcriptional regulator
MIOPJFLD_00545 1e-107 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
MIOPJFLD_00546 3.1e-191 ydeR EGP Major facilitator Superfamily
MIOPJFLD_00547 2.1e-103 ydeS K Transcriptional regulator
MIOPJFLD_00548 6.3e-57 arsR K transcriptional
MIOPJFLD_00549 1.1e-229 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MIOPJFLD_00550 1.5e-146 ydfB J GNAT acetyltransferase
MIOPJFLD_00551 1.7e-160 ydfC EG EamA-like transporter family
MIOPJFLD_00552 6e-274 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MIOPJFLD_00553 1.4e-115 ydfE S Flavin reductase like domain
MIOPJFLD_00554 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
MIOPJFLD_00555 1e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MIOPJFLD_00557 2.6e-179 ydfH 2.7.13.3 T Histidine kinase
MIOPJFLD_00558 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MIOPJFLD_00559 0.0 ydfJ S drug exporters of the RND superfamily
MIOPJFLD_00560 1.4e-175 S Alpha/beta hydrolase family
MIOPJFLD_00561 8.5e-117 S Protein of unknown function (DUF554)
MIOPJFLD_00562 9.2e-147 K Bacterial transcription activator, effector binding domain
MIOPJFLD_00563 7.8e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MIOPJFLD_00564 1.4e-110 ydfN C nitroreductase
MIOPJFLD_00565 1.2e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
MIOPJFLD_00566 8.8e-63 mhqP S DoxX
MIOPJFLD_00567 7e-56 traF CO Thioredoxin
MIOPJFLD_00569 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
MIOPJFLD_00570 6.3e-29
MIOPJFLD_00572 4.4e-118 ydfR S Protein of unknown function (DUF421)
MIOPJFLD_00573 7.6e-121 ydfS S Protein of unknown function (DUF421)
MIOPJFLD_00574 1.7e-75 cotP O Belongs to the small heat shock protein (HSP20) family
MIOPJFLD_00575 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
MIOPJFLD_00576 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
MIOPJFLD_00577 2.8e-100 K Bacterial regulatory proteins, tetR family
MIOPJFLD_00578 1.6e-52 S DoxX-like family
MIOPJFLD_00579 3.8e-84 yycN 2.3.1.128 K Acetyltransferase
MIOPJFLD_00580 4e-298 expZ S ABC transporter
MIOPJFLD_00581 4e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
MIOPJFLD_00582 2.5e-89 dinB S DinB family
MIOPJFLD_00583 8.9e-79 K helix_turn_helix multiple antibiotic resistance protein
MIOPJFLD_00584 0.0 ydgH S drug exporters of the RND superfamily
MIOPJFLD_00585 1e-113 drgA C nitroreductase
MIOPJFLD_00586 2.4e-69 ydgJ K Winged helix DNA-binding domain
MIOPJFLD_00587 7.4e-209 tcaB EGP Major facilitator Superfamily
MIOPJFLD_00588 1.2e-121 ydhB S membrane transporter protein
MIOPJFLD_00589 6.5e-122 ydhC K FCD
MIOPJFLD_00590 1.6e-243 ydhD M Glycosyl hydrolase
MIOPJFLD_00591 2.7e-227 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MIOPJFLD_00592 6.2e-123
MIOPJFLD_00593 1.8e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
MIOPJFLD_00594 2.1e-66 frataxin S Domain of unknown function (DU1801)
MIOPJFLD_00596 2.8e-82 K Acetyltransferase (GNAT) domain
MIOPJFLD_00597 1.9e-183 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
MIOPJFLD_00598 2.5e-98 ydhK M Protein of unknown function (DUF1541)
MIOPJFLD_00599 4.6e-200 pbuE EGP Major facilitator Superfamily
MIOPJFLD_00600 1.9e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
MIOPJFLD_00601 3e-51 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
MIOPJFLD_00602 2.6e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MIOPJFLD_00603 6.2e-284 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MIOPJFLD_00604 1.1e-132 ydhQ K UTRA
MIOPJFLD_00605 8.9e-167 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
MIOPJFLD_00606 2.5e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
MIOPJFLD_00607 6.2e-215 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
MIOPJFLD_00608 6.1e-157 ydhU P Catalase
MIOPJFLD_00611 3.4e-39 S COG NOG14552 non supervised orthologous group
MIOPJFLD_00612 7.8e-08
MIOPJFLD_00614 5.8e-180 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MIOPJFLD_00615 1.2e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
MIOPJFLD_00616 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
MIOPJFLD_00617 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MIOPJFLD_00618 1.4e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MIOPJFLD_00619 0.0 ydiF S ABC transporter
MIOPJFLD_00620 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MIOPJFLD_00621 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MIOPJFLD_00622 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MIOPJFLD_00623 7.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MIOPJFLD_00624 2.9e-27 ydiK S Domain of unknown function (DUF4305)
MIOPJFLD_00625 1.3e-128 ydiL S CAAX protease self-immunity
MIOPJFLD_00626 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MIOPJFLD_00627 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MIOPJFLD_00628 3.6e-153 ydjC S Abhydrolase domain containing 18
MIOPJFLD_00629 0.0 K NB-ARC domain
MIOPJFLD_00630 9.4e-200 gutB 1.1.1.14 E Dehydrogenase
MIOPJFLD_00631 3.3e-253 gutA G MFS/sugar transport protein
MIOPJFLD_00632 7.5e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
MIOPJFLD_00633 4.3e-113 pspA KT Phage shock protein A
MIOPJFLD_00634 3.7e-177 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MIOPJFLD_00635 4.9e-134 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
MIOPJFLD_00636 4.1e-149 ydjI S virion core protein (lumpy skin disease virus)
MIOPJFLD_00637 3e-195 S Ion transport 2 domain protein
MIOPJFLD_00638 2.3e-257 iolT EGP Major facilitator Superfamily
MIOPJFLD_00639 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
MIOPJFLD_00640 4.5e-64 ydjM M Lytic transglycolase
MIOPJFLD_00641 2.1e-151 ydjN U Involved in the tonB-independent uptake of proteins
MIOPJFLD_00643 1.4e-34 ydjO S Cold-inducible protein YdjO
MIOPJFLD_00644 3.8e-156 ydjP I Alpha/beta hydrolase family
MIOPJFLD_00645 4.8e-174 yeaA S Protein of unknown function (DUF4003)
MIOPJFLD_00646 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
MIOPJFLD_00647 4.4e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
MIOPJFLD_00648 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MIOPJFLD_00649 1.9e-175 yeaC S COG0714 MoxR-like ATPases
MIOPJFLD_00650 5.8e-222 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
MIOPJFLD_00651 0.0 yebA E COG1305 Transglutaminase-like enzymes
MIOPJFLD_00652 8.3e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MIOPJFLD_00653 1.2e-83 K Belongs to the sigma-70 factor family. ECF subfamily
MIOPJFLD_00654 3.3e-256 S Domain of unknown function (DUF4179)
MIOPJFLD_00655 1e-211 pbuG S permease
MIOPJFLD_00656 4.4e-117 yebC M Membrane
MIOPJFLD_00658 8.9e-93 yebE S UPF0316 protein
MIOPJFLD_00659 8e-28 yebG S NETI protein
MIOPJFLD_00660 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MIOPJFLD_00661 5e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MIOPJFLD_00662 2.8e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MIOPJFLD_00663 3.1e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MIOPJFLD_00664 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MIOPJFLD_00665 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MIOPJFLD_00666 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MIOPJFLD_00667 3.6e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MIOPJFLD_00668 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MIOPJFLD_00669 8.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MIOPJFLD_00670 3e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MIOPJFLD_00671 5.9e-233 purD 6.3.4.13 F Belongs to the GARS family
MIOPJFLD_00672 1e-72 K helix_turn_helix ASNC type
MIOPJFLD_00673 4.4e-228 yjeH E Amino acid permease
MIOPJFLD_00674 2.7e-27 S Protein of unknown function (DUF2892)
MIOPJFLD_00675 0.0 yerA 3.5.4.2 F adenine deaminase
MIOPJFLD_00676 1.3e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
MIOPJFLD_00677 2.4e-50 yerC S protein conserved in bacteria
MIOPJFLD_00678 1e-303 yerD 1.4.7.1 E Belongs to the glutamate synthase family
MIOPJFLD_00680 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MIOPJFLD_00681 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MIOPJFLD_00682 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MIOPJFLD_00683 7e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
MIOPJFLD_00684 3.2e-197 yerI S homoserine kinase type II (protein kinase fold)
MIOPJFLD_00685 1.6e-123 sapB S MgtC SapB transporter
MIOPJFLD_00686 3.2e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MIOPJFLD_00687 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MIOPJFLD_00688 3.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MIOPJFLD_00689 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MIOPJFLD_00690 2.1e-146 yerO K Transcriptional regulator
MIOPJFLD_00691 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MIOPJFLD_00692 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MIOPJFLD_00693 4.1e-256 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MIOPJFLD_00694 6.1e-35
MIOPJFLD_00695 3e-81 S Protein of unknown function, DUF600
MIOPJFLD_00696 0.0 L nucleic acid phosphodiester bond hydrolysis
MIOPJFLD_00697 4e-179 3.4.24.40 CO amine dehydrogenase activity
MIOPJFLD_00698 8.5e-207 S Tetratricopeptide repeat
MIOPJFLD_00700 2.7e-126 yeeN K transcriptional regulatory protein
MIOPJFLD_00702 8.2e-101 dhaR3 K Transcriptional regulator
MIOPJFLD_00703 6.9e-80 yesE S SnoaL-like domain
MIOPJFLD_00704 2.5e-150 yesF GM NAD(P)H-binding
MIOPJFLD_00705 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
MIOPJFLD_00706 1.5e-45 cotJB S CotJB protein
MIOPJFLD_00707 5.2e-104 cotJC P Spore Coat
MIOPJFLD_00708 1.3e-101 yesJ K Acetyltransferase (GNAT) family
MIOPJFLD_00710 1.2e-101 yesL S Protein of unknown function, DUF624
MIOPJFLD_00711 0.0 yesM 2.7.13.3 T Histidine kinase
MIOPJFLD_00712 5.2e-201 yesN K helix_turn_helix, arabinose operon control protein
MIOPJFLD_00713 1.2e-246 yesO G Bacterial extracellular solute-binding protein
MIOPJFLD_00714 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
MIOPJFLD_00715 1.2e-163 yesQ P Binding-protein-dependent transport system inner membrane component
MIOPJFLD_00716 2.3e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
MIOPJFLD_00717 0.0 yesS K Transcriptional regulator
MIOPJFLD_00718 3e-130 E GDSL-like Lipase/Acylhydrolase
MIOPJFLD_00719 2.1e-125 yesU S Domain of unknown function (DUF1961)
MIOPJFLD_00720 3.9e-113 yesV S Protein of unknown function, DUF624
MIOPJFLD_00721 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
MIOPJFLD_00722 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
MIOPJFLD_00723 2e-123 yesY E GDSL-like Lipase/Acylhydrolase
MIOPJFLD_00724 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
MIOPJFLD_00725 0.0 yetA
MIOPJFLD_00726 9e-289 lplA G Bacterial extracellular solute-binding protein
MIOPJFLD_00727 3.2e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
MIOPJFLD_00728 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
MIOPJFLD_00729 7.1e-253 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
MIOPJFLD_00730 5.2e-122 yetF S membrane
MIOPJFLD_00731 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
MIOPJFLD_00732 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MIOPJFLD_00733 2.4e-34
MIOPJFLD_00734 1.9e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MIOPJFLD_00735 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
MIOPJFLD_00736 5.3e-105 yetJ S Belongs to the BI1 family
MIOPJFLD_00737 1.2e-158 yetK EG EamA-like transporter family
MIOPJFLD_00738 2.1e-88 yetL K helix_turn_helix multiple antibiotic resistance protein
MIOPJFLD_00739 3e-209 yetM CH FAD binding domain
MIOPJFLD_00741 3e-193 yetN S Protein of unknown function (DUF3900)
MIOPJFLD_00742 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
MIOPJFLD_00743 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MIOPJFLD_00744 7.4e-146 rfbF 2.7.7.33 JM Nucleotidyl transferase
MIOPJFLD_00745 3.2e-172 yfnG 4.2.1.45 M dehydratase
MIOPJFLD_00746 5.1e-178 yfnF M Nucleotide-diphospho-sugar transferase
MIOPJFLD_00747 1.2e-224 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
MIOPJFLD_00748 3.9e-189 yfnD M Nucleotide-diphospho-sugar transferase
MIOPJFLD_00749 1.5e-204 fsr P COG0477 Permeases of the major facilitator superfamily
MIOPJFLD_00750 8.1e-131 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MIOPJFLD_00751 6.4e-241 yfnA E amino acid
MIOPJFLD_00752 1.8e-278 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MIOPJFLD_00753 1.1e-113 yfmS NT chemotaxis protein
MIOPJFLD_00754 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MIOPJFLD_00755 1.3e-73 yfmQ S Uncharacterised protein from bacillus cereus group
MIOPJFLD_00756 1.4e-69 yfmP K transcriptional
MIOPJFLD_00757 6.2e-208 yfmO EGP Major facilitator Superfamily
MIOPJFLD_00758 1.6e-59 isp O Subtilase family
MIOPJFLD_00759 6.4e-19
MIOPJFLD_00761 6.3e-57
MIOPJFLD_00762 7.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MIOPJFLD_00763 4.5e-200 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
MIOPJFLD_00764 2.5e-77 yfmK 2.3.1.128 K acetyltransferase
MIOPJFLD_00765 5.7e-186 yfmJ S N-terminal domain of oxidoreductase
MIOPJFLD_00766 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
MIOPJFLD_00767 2.4e-168 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIOPJFLD_00768 1.2e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIOPJFLD_00769 4.2e-167 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
MIOPJFLD_00770 2.9e-24 S Protein of unknown function (DUF3212)
MIOPJFLD_00771 1.3e-57 yflT S Heat induced stress protein YflT
MIOPJFLD_00772 1.4e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
MIOPJFLD_00773 5.5e-235 yflS P Sodium:sulfate symporter transmembrane region
MIOPJFLD_00774 1.4e-287 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MIOPJFLD_00775 2.2e-117 citT T response regulator
MIOPJFLD_00776 1.7e-179 yflP S Tripartite tricarboxylate transporter family receptor
MIOPJFLD_00777 2.5e-226 citM C Citrate transporter
MIOPJFLD_00778 3.9e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
MIOPJFLD_00779 1.3e-215 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MIOPJFLD_00780 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MIOPJFLD_00781 3.2e-121 yflK S protein conserved in bacteria
MIOPJFLD_00782 8.9e-18 yflJ S Protein of unknown function (DUF2639)
MIOPJFLD_00783 4.1e-19 yflI
MIOPJFLD_00784 2.4e-50 yflH S Protein of unknown function (DUF3243)
MIOPJFLD_00785 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
MIOPJFLD_00786 3.3e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MIOPJFLD_00787 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MIOPJFLD_00788 6e-67 yhdN S Domain of unknown function (DUF1992)
MIOPJFLD_00789 2.3e-137 agcS_1 E Sodium alanine symporter
MIOPJFLD_00790 1.8e-105 agcS_1 E Sodium alanine symporter
MIOPJFLD_00791 1.9e-192 E Spore germination protein
MIOPJFLD_00793 2.5e-206 yfkR S spore germination
MIOPJFLD_00794 9.9e-283 yfkQ EG Spore germination protein
MIOPJFLD_00795 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MIOPJFLD_00796 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
MIOPJFLD_00797 6.7e-133 treR K transcriptional
MIOPJFLD_00798 1.4e-124 yfkO C nitroreductase
MIOPJFLD_00799 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
MIOPJFLD_00800 9.6e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
MIOPJFLD_00801 8.9e-207 ydiM EGP Major facilitator Superfamily
MIOPJFLD_00802 2.3e-28 yfkK S Belongs to the UPF0435 family
MIOPJFLD_00803 2.2e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MIOPJFLD_00804 9.2e-50 yfkI S gas vesicle protein
MIOPJFLD_00805 9.7e-144 yihY S Belongs to the UPF0761 family
MIOPJFLD_00806 5e-08
MIOPJFLD_00807 1.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
MIOPJFLD_00808 6.1e-183 cax P COG0387 Ca2 H antiporter
MIOPJFLD_00809 1.2e-146 yfkD S YfkD-like protein
MIOPJFLD_00810 3e-148 yfkC M Mechanosensitive ion channel
MIOPJFLD_00811 5.4e-222 yfkA S YfkB-like domain
MIOPJFLD_00812 1.1e-26 yfjT
MIOPJFLD_00813 1.7e-153 pdaA G deacetylase
MIOPJFLD_00814 2e-147 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MIOPJFLD_00815 1.7e-184 corA P Mediates influx of magnesium ions
MIOPJFLD_00816 1e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MIOPJFLD_00817 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MIOPJFLD_00818 3.9e-44 S YfzA-like protein
MIOPJFLD_00819 1.8e-189 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MIOPJFLD_00820 8.4e-81 yfjM S Psort location Cytoplasmic, score
MIOPJFLD_00821 4e-26 yfjL
MIOPJFLD_00822 2.6e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MIOPJFLD_00823 3.8e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MIOPJFLD_00824 9.3e-196 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MIOPJFLD_00825 1.4e-251 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MIOPJFLD_00826 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
MIOPJFLD_00827 9.8e-25 sspH S Belongs to the SspH family
MIOPJFLD_00828 4e-56 yfjF S UPF0060 membrane protein
MIOPJFLD_00829 1.9e-79 S Family of unknown function (DUF5381)
MIOPJFLD_00830 1.8e-101 yfjD S Family of unknown function (DUF5381)
MIOPJFLD_00831 4.1e-144 yfjC
MIOPJFLD_00832 2.3e-189 yfjB
MIOPJFLD_00833 1.1e-44 yfjA S Belongs to the WXG100 family
MIOPJFLD_00834 2.9e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MIOPJFLD_00835 1e-139 glvR K Helix-turn-helix domain, rpiR family
MIOPJFLD_00836 2e-294 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MIOPJFLD_00837 0.0 yobO M COG5434 Endopolygalacturonase
MIOPJFLD_00838 4.4e-308 yfiB3 V ABC transporter
MIOPJFLD_00839 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
MIOPJFLD_00840 1.1e-63 mhqP S DoxX
MIOPJFLD_00841 4.1e-161 yfiE 1.13.11.2 S glyoxalase
MIOPJFLD_00842 3e-173 K AraC-like ligand binding domain
MIOPJFLD_00843 2.2e-260 iolT EGP Major facilitator Superfamily
MIOPJFLD_00844 2.2e-176 G Xylose isomerase
MIOPJFLD_00845 4.3e-230 S Oxidoreductase
MIOPJFLD_00846 5.3e-188 yxjM T Histidine kinase
MIOPJFLD_00847 2.8e-109 KT LuxR family transcriptional regulator
MIOPJFLD_00848 4.6e-166 V ABC transporter, ATP-binding protein
MIOPJFLD_00849 8.9e-207 V ABC-2 family transporter protein
MIOPJFLD_00850 1.8e-204 V COG0842 ABC-type multidrug transport system, permease component
MIOPJFLD_00851 8.3e-99 padR K transcriptional
MIOPJFLD_00852 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
MIOPJFLD_00853 4.5e-197 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MIOPJFLD_00854 3.2e-107 yfiR K Transcriptional regulator
MIOPJFLD_00855 1.8e-213 yfiS EGP Major facilitator Superfamily
MIOPJFLD_00856 4.7e-99 yfiT S Belongs to the metal hydrolase YfiT family
MIOPJFLD_00857 3.4e-283 yfiU EGP Major facilitator Superfamily
MIOPJFLD_00858 4.9e-79 yfiV K transcriptional
MIOPJFLD_00859 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MIOPJFLD_00860 2.8e-174 yfiY P ABC transporter substrate-binding protein
MIOPJFLD_00861 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIOPJFLD_00862 6.8e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIOPJFLD_00863 1.1e-166 yfhB 5.3.3.17 S PhzF family
MIOPJFLD_00864 1.5e-106 yfhC C nitroreductase
MIOPJFLD_00865 6.1e-25 yfhD S YfhD-like protein
MIOPJFLD_00867 7.9e-171 yfhF S nucleoside-diphosphate sugar epimerase
MIOPJFLD_00868 2.5e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
MIOPJFLD_00869 9.7e-52 yfhH S Protein of unknown function (DUF1811)
MIOPJFLD_00871 1.1e-209 yfhI EGP Major facilitator Superfamily
MIOPJFLD_00872 6.2e-20 sspK S reproduction
MIOPJFLD_00873 1.3e-44 yfhJ S WVELL protein
MIOPJFLD_00874 2.4e-87 batE T Bacterial SH3 domain homologues
MIOPJFLD_00875 3.5e-51 yfhL S SdpI/YhfL protein family
MIOPJFLD_00876 1.3e-170 yfhM S Alpha beta hydrolase
MIOPJFLD_00877 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MIOPJFLD_00878 0.0 yfhO S Bacterial membrane protein YfhO
MIOPJFLD_00879 1.2e-185 yfhP S membrane-bound metal-dependent
MIOPJFLD_00880 3.3e-210 mutY L A G-specific
MIOPJFLD_00881 6.9e-36 yfhS
MIOPJFLD_00882 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIOPJFLD_00883 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
MIOPJFLD_00884 3.3e-37 ygaB S YgaB-like protein
MIOPJFLD_00885 1.3e-104 ygaC J Belongs to the UPF0374 family
MIOPJFLD_00886 3.1e-301 ygaD V ABC transporter
MIOPJFLD_00887 8.7e-180 ygaE S Membrane
MIOPJFLD_00888 4e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
MIOPJFLD_00889 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
MIOPJFLD_00890 4e-80 perR P Belongs to the Fur family
MIOPJFLD_00891 2.8e-55 ygzB S UPF0295 protein
MIOPJFLD_00892 6.7e-167 ygxA S Nucleotidyltransferase-like
MIOPJFLD_00893 3.4e-39 S COG NOG14552 non supervised orthologous group
MIOPJFLD_00898 7.8e-08
MIOPJFLD_00906 2e-08
MIOPJFLD_00910 1.9e-141 spo0M S COG4326 Sporulation control protein
MIOPJFLD_00911 1.2e-26
MIOPJFLD_00912 8.5e-75 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
MIOPJFLD_00913 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MIOPJFLD_00915 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
MIOPJFLD_00916 2.5e-138 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MIOPJFLD_00917 1.2e-169 ssuA M Sulfonate ABC transporter
MIOPJFLD_00918 9.4e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MIOPJFLD_00919 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
MIOPJFLD_00921 1.7e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MIOPJFLD_00922 4.1e-78 ygaO
MIOPJFLD_00923 4.4e-29 K Transcriptional regulator
MIOPJFLD_00925 7.9e-114 yhzB S B3/4 domain
MIOPJFLD_00926 1.5e-222 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MIOPJFLD_00927 1.7e-176 yhbB S Putative amidase domain
MIOPJFLD_00928 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MIOPJFLD_00929 1.8e-108 yhbD K Protein of unknown function (DUF4004)
MIOPJFLD_00930 2.7e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
MIOPJFLD_00931 2.1e-70 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
MIOPJFLD_00932 0.0 prkA T Ser protein kinase
MIOPJFLD_00933 2.5e-225 yhbH S Belongs to the UPF0229 family
MIOPJFLD_00934 2.2e-76 yhbI K DNA-binding transcription factor activity
MIOPJFLD_00935 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
MIOPJFLD_00936 3.1e-271 yhcA EGP Major facilitator Superfamily
MIOPJFLD_00937 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
MIOPJFLD_00938 1.5e-35 yhcC
MIOPJFLD_00939 7.8e-55
MIOPJFLD_00940 6.6e-60 yhcF K Transcriptional regulator
MIOPJFLD_00941 1.6e-123 yhcG V ABC transporter, ATP-binding protein
MIOPJFLD_00942 2.2e-165 yhcH V ABC transporter, ATP-binding protein
MIOPJFLD_00943 9.6e-164 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MIOPJFLD_00944 1e-30 cspB K Cold-shock protein
MIOPJFLD_00945 2e-149 metQ M Belongs to the nlpA lipoprotein family
MIOPJFLD_00946 1.3e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
MIOPJFLD_00947 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MIOPJFLD_00948 8.3e-78 S Protein of unknown function (DUF2812)
MIOPJFLD_00949 1.2e-49 K Transcriptional regulator PadR-like family
MIOPJFLD_00950 4.1e-40 yhcM
MIOPJFLD_00951 2.2e-65 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MIOPJFLD_00952 8.1e-166 yhcP
MIOPJFLD_00953 5.2e-100 yhcQ M Spore coat protein
MIOPJFLD_00954 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
MIOPJFLD_00955 4.6e-103 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
MIOPJFLD_00956 3e-170 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MIOPJFLD_00957 9.3e-68 yhcU S Family of unknown function (DUF5365)
MIOPJFLD_00958 9.9e-68 yhcV S COG0517 FOG CBS domain
MIOPJFLD_00959 1.3e-119 yhcW 5.4.2.6 S hydrolase
MIOPJFLD_00960 1.7e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MIOPJFLD_00961 1.6e-260 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MIOPJFLD_00962 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MIOPJFLD_00963 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
MIOPJFLD_00964 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MIOPJFLD_00965 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MIOPJFLD_00966 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
MIOPJFLD_00967 8e-213 yhcY 2.7.13.3 T Histidine kinase
MIOPJFLD_00968 7.2e-110 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MIOPJFLD_00969 1.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
MIOPJFLD_00970 1.2e-38 yhdB S YhdB-like protein
MIOPJFLD_00971 3.1e-53 yhdC S Protein of unknown function (DUF3889)
MIOPJFLD_00972 1.8e-188 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MIOPJFLD_00973 6e-76 nsrR K Transcriptional regulator
MIOPJFLD_00974 1.3e-237 ygxB M Conserved TM helix
MIOPJFLD_00975 6.3e-276 ycgB S Stage V sporulation protein R
MIOPJFLD_00976 4.9e-257 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
MIOPJFLD_00977 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MIOPJFLD_00978 3.8e-162 citR K Transcriptional regulator
MIOPJFLD_00979 2.5e-203 citA 2.3.3.1 C Belongs to the citrate synthase family
MIOPJFLD_00980 1e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIOPJFLD_00981 1.7e-249 yhdG E amino acid
MIOPJFLD_00982 8.2e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MIOPJFLD_00983 1.2e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MIOPJFLD_00984 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MIOPJFLD_00985 8.1e-45 yhdK S Sigma-M inhibitor protein
MIOPJFLD_00986 6.6e-201 yhdL S Sigma factor regulator N-terminal
MIOPJFLD_00987 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
MIOPJFLD_00988 1.5e-191 yhdN C Aldo keto reductase
MIOPJFLD_00989 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MIOPJFLD_00990 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MIOPJFLD_00991 4.1e-74 cueR K transcriptional
MIOPJFLD_00992 2e-222 yhdR 2.6.1.1 E Aminotransferase
MIOPJFLD_00993 3.9e-246 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
MIOPJFLD_00994 3.2e-43 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MIOPJFLD_00995 9.6e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MIOPJFLD_00996 1.8e-133 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MIOPJFLD_00998 9.9e-184 yhdY M Mechanosensitive ion channel
MIOPJFLD_00999 3.8e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MIOPJFLD_01000 4.8e-146 yheN G deacetylase
MIOPJFLD_01001 1.8e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
MIOPJFLD_01002 1.2e-231 nhaC C Na H antiporter
MIOPJFLD_01003 3.8e-83 nhaX T Belongs to the universal stress protein A family
MIOPJFLD_01004 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
MIOPJFLD_01005 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
MIOPJFLD_01006 5.3e-110 yheG GM NAD(P)H-binding
MIOPJFLD_01007 6.3e-28 sspB S spore protein
MIOPJFLD_01008 1.3e-36 yheE S Family of unknown function (DUF5342)
MIOPJFLD_01009 4.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
MIOPJFLD_01010 3.7e-215 yheC HJ YheC/D like ATP-grasp
MIOPJFLD_01011 1.4e-201 yheB S Belongs to the UPF0754 family
MIOPJFLD_01012 9.5e-48 yheA S Belongs to the UPF0342 family
MIOPJFLD_01013 3.7e-204 yhaZ L DNA alkylation repair enzyme
MIOPJFLD_01014 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
MIOPJFLD_01015 1.8e-292 hemZ H coproporphyrinogen III oxidase
MIOPJFLD_01016 2.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
MIOPJFLD_01017 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
MIOPJFLD_01019 1.9e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
MIOPJFLD_01020 1.1e-26 S YhzD-like protein
MIOPJFLD_01021 6.8e-167 yhaQ S ABC transporter, ATP-binding protein
MIOPJFLD_01022 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
MIOPJFLD_01023 2.6e-225 yhaO L DNA repair exonuclease
MIOPJFLD_01024 0.0 yhaN L AAA domain
MIOPJFLD_01025 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
MIOPJFLD_01026 1.6e-21 yhaL S Sporulation protein YhaL
MIOPJFLD_01027 2e-115 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MIOPJFLD_01028 8.7e-90 yhaK S Putative zincin peptidase
MIOPJFLD_01029 1.3e-54 yhaI S Protein of unknown function (DUF1878)
MIOPJFLD_01030 1e-113 hpr K Negative regulator of protease production and sporulation
MIOPJFLD_01031 8.2e-39 yhaH S YtxH-like protein
MIOPJFLD_01032 5.4e-21
MIOPJFLD_01033 3.6e-80 trpP S Tryptophan transporter TrpP
MIOPJFLD_01034 7.1e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MIOPJFLD_01035 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MIOPJFLD_01036 4.6e-137 ecsA V transporter (ATP-binding protein)
MIOPJFLD_01037 5.4e-215 ecsB U ABC transporter
MIOPJFLD_01038 4.5e-113 ecsC S EcsC protein family
MIOPJFLD_01039 1.1e-228 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MIOPJFLD_01040 1.9e-240 yhfA C membrane
MIOPJFLD_01041 4.1e-28 1.15.1.2 C Rubrerythrin
MIOPJFLD_01042 6.4e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
MIOPJFLD_01043 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MIOPJFLD_01044 4.5e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MIOPJFLD_01045 8.9e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
MIOPJFLD_01046 2.2e-265 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MIOPJFLD_01047 5.4e-101 yhgD K Transcriptional regulator
MIOPJFLD_01048 1.1e-213 yhgE S YhgE Pip N-terminal domain protein
MIOPJFLD_01049 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MIOPJFLD_01050 1.7e-134 yhfC S Putative membrane peptidase family (DUF2324)
MIOPJFLD_01051 5.1e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
MIOPJFLD_01052 3.7e-72 3.4.13.21 S ASCH
MIOPJFLD_01053 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MIOPJFLD_01054 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
MIOPJFLD_01055 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
MIOPJFLD_01056 1.2e-109 yhfK GM NmrA-like family
MIOPJFLD_01057 5e-298 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
MIOPJFLD_01058 1.9e-65 yhfM
MIOPJFLD_01059 6.9e-237 yhfN 3.4.24.84 O Peptidase M48
MIOPJFLD_01060 4.7e-197 aprE 3.4.21.62 O Belongs to the peptidase S8 family
MIOPJFLD_01061 1.1e-77 VY92_01935 K acetyltransferase
MIOPJFLD_01062 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
MIOPJFLD_01063 2.8e-158 yfmC M Periplasmic binding protein
MIOPJFLD_01064 3e-107 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
MIOPJFLD_01065 4.4e-200 vraB 2.3.1.9 I Belongs to the thiolase family
MIOPJFLD_01066 1.5e-277 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
MIOPJFLD_01067 5e-91 bioY S BioY family
MIOPJFLD_01068 1.7e-182 hemAT NT chemotaxis protein
MIOPJFLD_01069 5.7e-299 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
MIOPJFLD_01070 4.7e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIOPJFLD_01071 1.3e-32 yhzC S IDEAL
MIOPJFLD_01072 9.3e-109 comK K Competence transcription factor
MIOPJFLD_01073 6.2e-168 IQ Enoyl-(Acyl carrier protein) reductase
MIOPJFLD_01074 1.2e-39 yhjA S Excalibur calcium-binding domain
MIOPJFLD_01075 5.7e-264 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MIOPJFLD_01076 6.9e-27 yhjC S Protein of unknown function (DUF3311)
MIOPJFLD_01077 6.7e-60 yhjD
MIOPJFLD_01078 9.1e-110 yhjE S SNARE associated Golgi protein
MIOPJFLD_01079 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
MIOPJFLD_01080 4.4e-280 yhjG CH FAD binding domain
MIOPJFLD_01081 2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
MIOPJFLD_01084 2.9e-213 glcP G Major Facilitator Superfamily
MIOPJFLD_01085 7.1e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
MIOPJFLD_01086 1.8e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
MIOPJFLD_01087 1.2e-252 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
MIOPJFLD_01088 1.6e-188 yhjM 5.1.1.1 K Transcriptional regulator
MIOPJFLD_01089 4.2e-201 abrB S membrane
MIOPJFLD_01090 7.4e-209 EGP Transmembrane secretion effector
MIOPJFLD_01091 0.0 S Sugar transport-related sRNA regulator N-term
MIOPJFLD_01092 2e-36 yhjQ C COG1145 Ferredoxin
MIOPJFLD_01093 4.9e-78 yhjR S Rubrerythrin
MIOPJFLD_01094 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
MIOPJFLD_01095 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MIOPJFLD_01096 1.8e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MIOPJFLD_01097 0.0 sbcC L COG0419 ATPase involved in DNA repair
MIOPJFLD_01098 1.1e-49 yisB V COG1403 Restriction endonuclease
MIOPJFLD_01099 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
MIOPJFLD_01100 5.3e-63 gerPE S Spore germination protein GerPE
MIOPJFLD_01101 1.1e-23 gerPD S Spore germination protein
MIOPJFLD_01102 5.3e-54 gerPC S Spore germination protein
MIOPJFLD_01103 4e-34 gerPB S cell differentiation
MIOPJFLD_01104 1.9e-33 gerPA S Spore germination protein
MIOPJFLD_01105 1.5e-22 yisI S Spo0E like sporulation regulatory protein
MIOPJFLD_01106 2.7e-174 cotH M Spore Coat
MIOPJFLD_01107 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MIOPJFLD_01108 3e-57 yisL S UPF0344 protein
MIOPJFLD_01109 0.0 wprA O Belongs to the peptidase S8 family
MIOPJFLD_01110 1.5e-100 yisN S Protein of unknown function (DUF2777)
MIOPJFLD_01111 0.0 asnO 6.3.5.4 E Asparagine synthase
MIOPJFLD_01112 4.7e-88 yizA S Damage-inducible protein DinB
MIOPJFLD_01113 4.1e-147 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
MIOPJFLD_01114 1.5e-242 yisQ V Mate efflux family protein
MIOPJFLD_01115 1.2e-160 yisR K Transcriptional regulator
MIOPJFLD_01116 2.4e-184 purR K helix_turn _helix lactose operon repressor
MIOPJFLD_01117 6.3e-193 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
MIOPJFLD_01118 1.5e-91 yisT S DinB family
MIOPJFLD_01119 2e-106 argO S Lysine exporter protein LysE YggA
MIOPJFLD_01120 1.2e-277 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MIOPJFLD_01121 4e-36 mcbG S Pentapeptide repeats (9 copies)
MIOPJFLD_01122 1e-153 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MIOPJFLD_01123 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
MIOPJFLD_01124 1.3e-229 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
MIOPJFLD_01125 5.1e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
MIOPJFLD_01126 2e-118 comB 3.1.3.71 H Belongs to the ComB family
MIOPJFLD_01127 1.6e-140 yitD 4.4.1.19 S synthase
MIOPJFLD_01128 7.2e-113 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MIOPJFLD_01129 6e-221 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MIOPJFLD_01130 2e-228 yitG EGP Major facilitator Superfamily
MIOPJFLD_01131 1.8e-153 yitH K Acetyltransferase (GNAT) domain
MIOPJFLD_01132 1e-70 yjcF S Acetyltransferase (GNAT) domain
MIOPJFLD_01133 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MIOPJFLD_01134 4.3e-54 yajQ S Belongs to the UPF0234 family
MIOPJFLD_01135 6.9e-161 cvfB S protein conserved in bacteria
MIOPJFLD_01136 8.5e-94
MIOPJFLD_01137 1.4e-170
MIOPJFLD_01138 7.6e-97 S Sporulation delaying protein SdpA
MIOPJFLD_01139 1.5e-58 K Transcriptional regulator PadR-like family
MIOPJFLD_01140 6.6e-94
MIOPJFLD_01141 1.4e-44 yitR S Domain of unknown function (DUF3784)
MIOPJFLD_01142 1.3e-309 nprB 3.4.24.28 E Peptidase M4
MIOPJFLD_01143 1.2e-157 yitS S protein conserved in bacteria
MIOPJFLD_01144 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
MIOPJFLD_01145 5e-73 ipi S Intracellular proteinase inhibitor
MIOPJFLD_01146 2.8e-17 S Protein of unknown function (DUF3813)
MIOPJFLD_01148 6e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
MIOPJFLD_01149 1e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
MIOPJFLD_01150 6.2e-51 yitW S metal-sulfur cluster biosynthetic enzyme
MIOPJFLD_01151 1.5e-22 pilT S Proteolipid membrane potential modulator
MIOPJFLD_01152 4.9e-268 yitY C D-arabinono-1,4-lactone oxidase
MIOPJFLD_01153 1.7e-88 norB G Major Facilitator Superfamily
MIOPJFLD_01154 4.7e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MIOPJFLD_01155 3.1e-231 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MIOPJFLD_01156 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
MIOPJFLD_01157 4.4e-219 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
MIOPJFLD_01158 5.7e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MIOPJFLD_01159 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
MIOPJFLD_01160 2.5e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MIOPJFLD_01161 9.5e-28 yjzC S YjzC-like protein
MIOPJFLD_01162 2.3e-16 yjzD S Protein of unknown function (DUF2929)
MIOPJFLD_01163 5.2e-141 yjaU I carboxylic ester hydrolase activity
MIOPJFLD_01164 5.8e-100 yjaV
MIOPJFLD_01165 2.5e-183 med S Transcriptional activator protein med
MIOPJFLD_01166 7.3e-26 comZ S ComZ
MIOPJFLD_01167 2.7e-22 yjzB
MIOPJFLD_01168 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MIOPJFLD_01169 4e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MIOPJFLD_01170 1.1e-149 yjaZ O Zn-dependent protease
MIOPJFLD_01171 1.8e-184 appD P Belongs to the ABC transporter superfamily
MIOPJFLD_01172 4.2e-186 appF E Belongs to the ABC transporter superfamily
MIOPJFLD_01173 2.4e-287 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
MIOPJFLD_01174 7.7e-169 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIOPJFLD_01175 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIOPJFLD_01176 5e-147 yjbA S Belongs to the UPF0736 family
MIOPJFLD_01177 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
MIOPJFLD_01178 0.0 oppA E ABC transporter substrate-binding protein
MIOPJFLD_01179 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIOPJFLD_01180 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIOPJFLD_01181 3.4e-197 oppD P Belongs to the ABC transporter superfamily
MIOPJFLD_01182 5.5e-172 oppF E Belongs to the ABC transporter superfamily
MIOPJFLD_01183 4.1e-204 yjbB EGP Major Facilitator Superfamily
MIOPJFLD_01184 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MIOPJFLD_01185 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MIOPJFLD_01186 1.1e-110 yjbE P Integral membrane protein TerC family
MIOPJFLD_01187 4.4e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MIOPJFLD_01188 1e-220 yjbF S Competence protein
MIOPJFLD_01189 0.0 pepF E oligoendopeptidase F
MIOPJFLD_01190 1.8e-20
MIOPJFLD_01191 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
MIOPJFLD_01192 3.7e-72 yjbI S Bacterial-like globin
MIOPJFLD_01193 1.7e-99 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MIOPJFLD_01194 4.1e-101 yjbK S protein conserved in bacteria
MIOPJFLD_01195 7.8e-61 yjbL S Belongs to the UPF0738 family
MIOPJFLD_01196 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
MIOPJFLD_01197 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MIOPJFLD_01198 7.5e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MIOPJFLD_01199 5.1e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
MIOPJFLD_01200 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MIOPJFLD_01201 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MIOPJFLD_01202 4.6e-106 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
MIOPJFLD_01203 1.8e-214 thiO 1.4.3.19 E Glycine oxidase
MIOPJFLD_01204 2.6e-29 thiS H thiamine diphosphate biosynthetic process
MIOPJFLD_01205 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MIOPJFLD_01206 2.3e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MIOPJFLD_01207 2e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MIOPJFLD_01208 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
MIOPJFLD_01209 5.9e-54 yjbX S Spore coat protein
MIOPJFLD_01210 1.1e-80 cotZ S Spore coat protein
MIOPJFLD_01211 7.6e-96 cotY S Spore coat protein Z
MIOPJFLD_01212 4e-71 cotX S Spore Coat Protein X and V domain
MIOPJFLD_01213 9.9e-23 cotW
MIOPJFLD_01214 3e-55 cotV S Spore Coat Protein X and V domain
MIOPJFLD_01215 5.6e-56 yjcA S Protein of unknown function (DUF1360)
MIOPJFLD_01218 2.9e-38 spoVIF S Stage VI sporulation protein F
MIOPJFLD_01219 0.0 yjcD 3.6.4.12 L DNA helicase
MIOPJFLD_01220 1.7e-38
MIOPJFLD_01221 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MIOPJFLD_01222 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
MIOPJFLD_01223 5.3e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
MIOPJFLD_01224 3.2e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MIOPJFLD_01225 6.5e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MIOPJFLD_01226 1.2e-97 rimJ 2.3.1.128 J Alanine acetyltransferase
MIOPJFLD_01227 2.4e-212 yjcL S Protein of unknown function (DUF819)
MIOPJFLD_01230 1.6e-38
MIOPJFLD_01231 1.4e-28
MIOPJFLD_01232 5.2e-51 M nucleic acid phosphodiester bond hydrolysis
MIOPJFLD_01233 3.6e-172 M nucleic acid phosphodiester bond hydrolysis
MIOPJFLD_01234 4.9e-21
MIOPJFLD_01237 1.4e-22 S response regulator aspartate phosphatase
MIOPJFLD_01238 5.7e-88 S response regulator aspartate phosphatase
MIOPJFLD_01239 4.2e-46 yjcS S Antibiotic biosynthesis monooxygenase
MIOPJFLD_01240 5.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
MIOPJFLD_01242 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
MIOPJFLD_01243 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
MIOPJFLD_01244 4.3e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
MIOPJFLD_01245 7e-50 yjdF S Protein of unknown function (DUF2992)
MIOPJFLD_01246 7.6e-91 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
MIOPJFLD_01248 5.2e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MIOPJFLD_01249 4.2e-29 S Domain of unknown function (DUF4177)
MIOPJFLD_01250 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
MIOPJFLD_01251 3.1e-173 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MIOPJFLD_01253 3.2e-264 xynD 3.5.1.104 G Polysaccharide deacetylase
MIOPJFLD_01254 3e-81 S Protein of unknown function (DUF2690)
MIOPJFLD_01255 2.3e-20 yjfB S Putative motility protein
MIOPJFLD_01256 2.1e-104 yjfC O Predicted Zn-dependent protease (DUF2268)
MIOPJFLD_01257 7.3e-36 yjfC O Predicted Zn-dependent protease (DUF2268)
MIOPJFLD_01258 4.9e-34 T PhoQ Sensor
MIOPJFLD_01259 2e-103 yjgB S Domain of unknown function (DUF4309)
MIOPJFLD_01260 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
MIOPJFLD_01261 5.7e-95 yjgD S Protein of unknown function (DUF1641)
MIOPJFLD_01262 8.7e-07 S Domain of unknown function (DUF4352)
MIOPJFLD_01263 1.6e-111 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
MIOPJFLD_01265 1.4e-223 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
MIOPJFLD_01266 7.7e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MIOPJFLD_01267 8.2e-30
MIOPJFLD_01268 4.6e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
MIOPJFLD_01269 1.9e-122 ybbM S transport system, permease component
MIOPJFLD_01270 2e-135 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
MIOPJFLD_01271 1.1e-175 yjlA EG Putative multidrug resistance efflux transporter
MIOPJFLD_01272 1.3e-90 yjlB S Cupin domain
MIOPJFLD_01273 7.1e-66 yjlC S Protein of unknown function (DUF1641)
MIOPJFLD_01274 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
MIOPJFLD_01275 4.6e-279 uxaC 5.3.1.12 G glucuronate isomerase
MIOPJFLD_01276 2.7e-247 yjmB G symporter YjmB
MIOPJFLD_01277 4.2e-189 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
MIOPJFLD_01278 6.5e-190 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
MIOPJFLD_01279 5.8e-213 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
MIOPJFLD_01280 2e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MIOPJFLD_01281 8.3e-227 exuT G Sugar (and other) transporter
MIOPJFLD_01282 2.6e-183 exuR K transcriptional
MIOPJFLD_01283 2.1e-282 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
MIOPJFLD_01284 2.5e-283 uxaA 4.2.1.7, 4.4.1.24 G Altronate
MIOPJFLD_01285 9.7e-130 MA20_18170 S membrane transporter protein
MIOPJFLD_01286 1.4e-78 yjoA S DinB family
MIOPJFLD_01287 3.6e-246 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
MIOPJFLD_01288 1e-212 S response regulator aspartate phosphatase
MIOPJFLD_01290 6.3e-41 S YCII-related domain
MIOPJFLD_01291 7.2e-167 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
MIOPJFLD_01292 2.3e-60 yjqA S Bacterial PH domain
MIOPJFLD_01293 3.3e-109 yjqB S Pfam:DUF867
MIOPJFLD_01294 4.4e-160 ydbD P Catalase
MIOPJFLD_01295 1.6e-111 xkdA E IrrE N-terminal-like domain
MIOPJFLD_01296 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
MIOPJFLD_01298 5.9e-157 xkdB K sequence-specific DNA binding
MIOPJFLD_01299 4.1e-118 xkdC L Bacterial dnaA protein
MIOPJFLD_01302 2.3e-09 yqaO S Phage-like element PBSX protein XtrA
MIOPJFLD_01303 7e-84 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MIOPJFLD_01304 1.5e-138 xtmA L phage terminase small subunit
MIOPJFLD_01305 1.8e-253 xtmB S phage terminase, large subunit
MIOPJFLD_01306 1.6e-285 yqbA S portal protein
MIOPJFLD_01307 2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
MIOPJFLD_01308 5.8e-169 xkdG S Phage capsid family
MIOPJFLD_01309 5.1e-63 yqbG S Protein of unknown function (DUF3199)
MIOPJFLD_01310 2.5e-64 yqbH S Domain of unknown function (DUF3599)
MIOPJFLD_01311 2.9e-87 xkdI S Bacteriophage HK97-gp10, putative tail-component
MIOPJFLD_01312 1.9e-77 xkdJ
MIOPJFLD_01313 2.5e-256 xkdK S Phage tail sheath C-terminal domain
MIOPJFLD_01314 6.1e-76 xkdM S Phage tail tube protein
MIOPJFLD_01315 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
MIOPJFLD_01316 0.0 xkdO L Transglycosylase SLT domain
MIOPJFLD_01317 3.7e-122 xkdP S Lysin motif
MIOPJFLD_01318 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
MIOPJFLD_01319 2.1e-39 xkdR S Protein of unknown function (DUF2577)
MIOPJFLD_01320 4.1e-69 xkdS S Protein of unknown function (DUF2634)
MIOPJFLD_01321 3.9e-190 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MIOPJFLD_01322 5.8e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
MIOPJFLD_01323 8.7e-41
MIOPJFLD_01324 0.0
MIOPJFLD_01325 1.5e-42 xkdW S XkdW protein
MIOPJFLD_01326 2.1e-21 xkdX
MIOPJFLD_01327 2.8e-154 xepA
MIOPJFLD_01328 2.8e-39 xhlA S Haemolysin XhlA
MIOPJFLD_01329 9.3e-40 xhlB S SPP1 phage holin
MIOPJFLD_01330 1.3e-162 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MIOPJFLD_01331 6.7e-23 spoIISB S Stage II sporulation protein SB
MIOPJFLD_01332 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
MIOPJFLD_01333 5.8e-175 pit P phosphate transporter
MIOPJFLD_01334 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
MIOPJFLD_01335 6.1e-241 steT E amino acid
MIOPJFLD_01336 6.1e-182 mhqA E COG0346 Lactoylglutathione lyase and related lyases
MIOPJFLD_01338 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MIOPJFLD_01339 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MIOPJFLD_01340 2.2e-209 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MIOPJFLD_01341 6.9e-134 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
MIOPJFLD_01342 5.1e-153 dppA E D-aminopeptidase
MIOPJFLD_01343 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIOPJFLD_01344 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIOPJFLD_01345 5.6e-186 dppD P Belongs to the ABC transporter superfamily
MIOPJFLD_01346 0.0 dppE E ABC transporter substrate-binding protein
MIOPJFLD_01348 3.5e-174 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
MIOPJFLD_01349 1.8e-198 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MIOPJFLD_01350 1.8e-164 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MIOPJFLD_01351 7.2e-186 ykfD E Belongs to the ABC transporter superfamily
MIOPJFLD_01352 1.8e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
MIOPJFLD_01353 2.7e-160 ykgA E Amidinotransferase
MIOPJFLD_01354 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
MIOPJFLD_01355 3.9e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MIOPJFLD_01356 1e-10
MIOPJFLD_01357 2.7e-129 ykjA S Protein of unknown function (DUF421)
MIOPJFLD_01358 8.8e-98 ykkA S Protein of unknown function (DUF664)
MIOPJFLD_01359 1.1e-97 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MIOPJFLD_01360 3.5e-55 ykkC P Multidrug resistance protein
MIOPJFLD_01361 7e-50 ykkD P Multidrug resistance protein
MIOPJFLD_01362 1.1e-169 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
MIOPJFLD_01363 2e-200 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MIOPJFLD_01364 4.5e-225 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MIOPJFLD_01365 3.7e-70 ohrA O Organic hydroperoxide resistance protein
MIOPJFLD_01366 4.4e-74 ohrR K COG1846 Transcriptional regulators
MIOPJFLD_01367 8.4e-72 ohrB O Organic hydroperoxide resistance protein
MIOPJFLD_01368 1.4e-86 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
MIOPJFLD_01369 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MIOPJFLD_01370 1.7e-176 isp O Belongs to the peptidase S8 family
MIOPJFLD_01371 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MIOPJFLD_01372 2.6e-135 ykoC P Cobalt transport protein
MIOPJFLD_01373 9.5e-308 P ABC transporter, ATP-binding protein
MIOPJFLD_01374 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
MIOPJFLD_01375 2.5e-109 ykoF S YKOF-related Family
MIOPJFLD_01376 1.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MIOPJFLD_01377 2.2e-241 ykoH 2.7.13.3 T Histidine kinase
MIOPJFLD_01378 1.8e-111 ykoI S Peptidase propeptide and YPEB domain
MIOPJFLD_01379 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
MIOPJFLD_01382 2.2e-222 mgtE P Acts as a magnesium transporter
MIOPJFLD_01383 1.4e-53 tnrA K transcriptional
MIOPJFLD_01384 5.9e-18
MIOPJFLD_01385 2.6e-25 ykoL
MIOPJFLD_01386 1.3e-81 mhqR K transcriptional
MIOPJFLD_01387 4e-217 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
MIOPJFLD_01388 2.7e-97 ykoP G polysaccharide deacetylase
MIOPJFLD_01389 3.5e-154 ykoQ S Calcineurin-like phosphoesterase superfamily domain
MIOPJFLD_01390 0.0 ykoS
MIOPJFLD_01391 2.1e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MIOPJFLD_01392 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
MIOPJFLD_01393 3.6e-160 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MIOPJFLD_01394 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
MIOPJFLD_01395 2.7e-109 ykoX S membrane-associated protein
MIOPJFLD_01396 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MIOPJFLD_01397 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MIOPJFLD_01398 7.7e-107 rsgI S Anti-sigma factor N-terminus
MIOPJFLD_01399 1.9e-26 sspD S small acid-soluble spore protein
MIOPJFLD_01400 3.3e-124 ykrK S Domain of unknown function (DUF1836)
MIOPJFLD_01401 3.5e-155 htpX O Belongs to the peptidase M48B family
MIOPJFLD_01402 1.1e-232 ktrB P COG0168 Trk-type K transport systems, membrane components
MIOPJFLD_01403 1.2e-10 ydfR S Protein of unknown function (DUF421)
MIOPJFLD_01404 4.1e-18 ykzE
MIOPJFLD_01405 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
MIOPJFLD_01406 0.0 kinE 2.7.13.3 T Histidine kinase
MIOPJFLD_01407 4.6e-88 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MIOPJFLD_01409 7.5e-197 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MIOPJFLD_01410 1.8e-228 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MIOPJFLD_01411 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MIOPJFLD_01412 9.8e-230 mtnE 2.6.1.83 E Aminotransferase
MIOPJFLD_01413 4.1e-231 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
MIOPJFLD_01414 8.3e-136 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MIOPJFLD_01415 1.6e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
MIOPJFLD_01416 2.9e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MIOPJFLD_01417 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
MIOPJFLD_01418 6.4e-09 S Spo0E like sporulation regulatory protein
MIOPJFLD_01419 1.4e-64 eag
MIOPJFLD_01420 1.6e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
MIOPJFLD_01421 1.3e-75 ykvE K transcriptional
MIOPJFLD_01422 2.5e-125 motB N Flagellar motor protein
MIOPJFLD_01423 2.7e-138 motA N flagellar motor
MIOPJFLD_01424 0.0 clpE O Belongs to the ClpA ClpB family
MIOPJFLD_01425 9e-179 ykvI S membrane
MIOPJFLD_01426 2.1e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MIOPJFLD_01427 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
MIOPJFLD_01428 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MIOPJFLD_01429 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MIOPJFLD_01430 2.4e-59 ykvN K HxlR-like helix-turn-helix
MIOPJFLD_01431 2.4e-133 IQ Enoyl-(Acyl carrier protein) reductase
MIOPJFLD_01432 2.1e-213 ykvP 3.5.1.28 M Glycosyl transferases group 1
MIOPJFLD_01433 3.5e-35 3.5.1.104 M LysM domain
MIOPJFLD_01434 9e-162 G Glycosyl hydrolases family 18
MIOPJFLD_01435 5.6e-46 ykvR S Protein of unknown function (DUF3219)
MIOPJFLD_01436 6e-25 ykvS S protein conserved in bacteria
MIOPJFLD_01437 2.8e-28
MIOPJFLD_01438 3.1e-102 ykvT 3.5.1.28 M Cell Wall Hydrolase
MIOPJFLD_01439 8.4e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MIOPJFLD_01440 9.2e-89 stoA CO thiol-disulfide
MIOPJFLD_01441 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
MIOPJFLD_01442 2.3e-09
MIOPJFLD_01443 1.3e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
MIOPJFLD_01445 1.4e-178 ykvZ 5.1.1.1 K Transcriptional regulator
MIOPJFLD_01447 7.6e-128 glcT K antiterminator
MIOPJFLD_01448 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MIOPJFLD_01449 2.1e-39 ptsH G phosphocarrier protein HPr
MIOPJFLD_01450 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MIOPJFLD_01451 7.2e-39 splA S Transcriptional regulator
MIOPJFLD_01452 1.3e-201 splB 4.1.99.14 L Spore photoproduct lyase
MIOPJFLD_01453 1.7e-125 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MIOPJFLD_01454 1.3e-258 mcpC NT chemotaxis protein
MIOPJFLD_01455 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MIOPJFLD_01456 4.6e-14 vgb H Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
MIOPJFLD_01457 7e-120 ykwD J protein with SCP PR1 domains
MIOPJFLD_01458 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
MIOPJFLD_01459 0.0 pilS 2.7.13.3 T Histidine kinase
MIOPJFLD_01460 4.4e-222 patA 2.6.1.1 E Aminotransferase
MIOPJFLD_01461 1.3e-15
MIOPJFLD_01462 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
MIOPJFLD_01463 1.7e-84 ykyB S YkyB-like protein
MIOPJFLD_01464 2.8e-238 ykuC EGP Major facilitator Superfamily
MIOPJFLD_01465 1.8e-87 ykuD S protein conserved in bacteria
MIOPJFLD_01466 1.4e-164 ykuE S Metallophosphoesterase
MIOPJFLD_01467 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIOPJFLD_01468 4.4e-233 ykuI T Diguanylate phosphodiesterase
MIOPJFLD_01469 3.9e-37 ykuJ S protein conserved in bacteria
MIOPJFLD_01470 4.4e-94 ykuK S Ribonuclease H-like
MIOPJFLD_01471 3.9e-27 ykzF S Antirepressor AbbA
MIOPJFLD_01472 1.6e-76 ykuL S CBS domain
MIOPJFLD_01473 3.5e-168 ccpC K Transcriptional regulator
MIOPJFLD_01474 5.9e-85 fld C Flavodoxin domain
MIOPJFLD_01475 2.2e-173 ykuO
MIOPJFLD_01476 3.9e-78 fld C Flavodoxin
MIOPJFLD_01477 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MIOPJFLD_01478 2.1e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MIOPJFLD_01479 9e-37 ykuS S Belongs to the UPF0180 family
MIOPJFLD_01480 8.8e-142 ykuT M Mechanosensitive ion channel
MIOPJFLD_01481 3.9e-101 ykuU O Alkyl hydroperoxide reductase
MIOPJFLD_01482 1.8e-80 ykuV CO thiol-disulfide
MIOPJFLD_01483 1.5e-93 rok K Repressor of ComK
MIOPJFLD_01484 4.6e-145 yknT
MIOPJFLD_01485 3.3e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MIOPJFLD_01486 5.3e-192 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MIOPJFLD_01487 2.6e-244 moeA 2.10.1.1 H molybdopterin
MIOPJFLD_01488 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
MIOPJFLD_01489 4.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
MIOPJFLD_01490 2.4e-31 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MIOPJFLD_01491 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
MIOPJFLD_01492 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
MIOPJFLD_01493 9.4e-116 yknW S Yip1 domain
MIOPJFLD_01494 3.3e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIOPJFLD_01495 7.2e-124 macB V ABC transporter, ATP-binding protein
MIOPJFLD_01496 4e-207 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
MIOPJFLD_01497 3.1e-136 fruR K Transcriptional regulator
MIOPJFLD_01498 5.3e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
MIOPJFLD_01499 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MIOPJFLD_01500 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MIOPJFLD_01501 8.1e-39 ykoA
MIOPJFLD_01502 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MIOPJFLD_01503 9e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MIOPJFLD_01504 1.3e-237 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
MIOPJFLD_01505 1.1e-12 S Uncharacterized protein YkpC
MIOPJFLD_01506 7.7e-183 mreB D Rod-share determining protein MreBH
MIOPJFLD_01507 1.5e-43 abrB K of stationary sporulation gene expression
MIOPJFLD_01508 1e-240 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
MIOPJFLD_01509 5.5e-155 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
MIOPJFLD_01510 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
MIOPJFLD_01511 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MIOPJFLD_01512 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MIOPJFLD_01513 8.2e-31 ykzG S Belongs to the UPF0356 family
MIOPJFLD_01514 2.1e-146 ykrA S hydrolases of the HAD superfamily
MIOPJFLD_01515 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MIOPJFLD_01517 1.1e-107 recN L Putative cell-wall binding lipoprotein
MIOPJFLD_01518 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MIOPJFLD_01519 1.1e-178 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MIOPJFLD_01520 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MIOPJFLD_01521 4.1e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MIOPJFLD_01522 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
MIOPJFLD_01523 1e-276 speA 4.1.1.19 E Arginine
MIOPJFLD_01524 1.7e-41 yktA S Belongs to the UPF0223 family
MIOPJFLD_01525 4.6e-117 yktB S Belongs to the UPF0637 family
MIOPJFLD_01526 7.1e-26 ykzI
MIOPJFLD_01527 1.7e-148 suhB 3.1.3.25 G Inositol monophosphatase
MIOPJFLD_01528 4.2e-75 ykzC S Acetyltransferase (GNAT) family
MIOPJFLD_01529 1e-170 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MIOPJFLD_01530 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
MIOPJFLD_01531 0.0 ylaA
MIOPJFLD_01532 3e-41 ylaB
MIOPJFLD_01533 8.7e-66 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
MIOPJFLD_01534 1.2e-11 sigC S Putative zinc-finger
MIOPJFLD_01535 2.6e-37 ylaE
MIOPJFLD_01536 8.2e-22 S Family of unknown function (DUF5325)
MIOPJFLD_01537 0.0 typA T GTP-binding protein TypA
MIOPJFLD_01538 5.6e-47 ylaH S YlaH-like protein
MIOPJFLD_01539 2.5e-32 ylaI S protein conserved in bacteria
MIOPJFLD_01540 4.4e-88 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MIOPJFLD_01541 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
MIOPJFLD_01542 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MIOPJFLD_01543 3.1e-170 glsA 3.5.1.2 E Belongs to the glutaminase family
MIOPJFLD_01544 8.7e-44 ylaN S Belongs to the UPF0358 family
MIOPJFLD_01545 2.5e-212 ftsW D Belongs to the SEDS family
MIOPJFLD_01546 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MIOPJFLD_01547 8.5e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MIOPJFLD_01548 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MIOPJFLD_01549 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MIOPJFLD_01550 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MIOPJFLD_01551 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MIOPJFLD_01552 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MIOPJFLD_01553 1.5e-166 ctaG S cytochrome c oxidase
MIOPJFLD_01554 7e-62 ylbA S YugN-like family
MIOPJFLD_01555 2.6e-74 ylbB T COG0517 FOG CBS domain
MIOPJFLD_01556 9.6e-200 ylbC S protein with SCP PR1 domains
MIOPJFLD_01557 4.1e-63 ylbD S Putative coat protein
MIOPJFLD_01558 6.7e-37 ylbE S YlbE-like protein
MIOPJFLD_01559 1.8e-75 ylbF S Belongs to the UPF0342 family
MIOPJFLD_01560 7.5e-39 ylbG S UPF0298 protein
MIOPJFLD_01561 5.4e-98 rsmD 2.1.1.171 L Methyltransferase
MIOPJFLD_01562 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MIOPJFLD_01563 9.5e-220 ylbJ S Sporulation integral membrane protein YlbJ
MIOPJFLD_01564 1.3e-137 ylbK S esterase of the alpha-beta hydrolase superfamily
MIOPJFLD_01565 6.8e-187 ylbL T Belongs to the peptidase S16 family
MIOPJFLD_01566 3.3e-228 ylbM S Belongs to the UPF0348 family
MIOPJFLD_01568 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
MIOPJFLD_01569 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MIOPJFLD_01570 3.4e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MIOPJFLD_01571 1.5e-88 ylbP K n-acetyltransferase
MIOPJFLD_01572 7.3e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MIOPJFLD_01573 1.5e-305 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MIOPJFLD_01574 2.9e-78 mraZ K Belongs to the MraZ family
MIOPJFLD_01575 1.6e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MIOPJFLD_01576 3.7e-44 ftsL D Essential cell division protein
MIOPJFLD_01577 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
MIOPJFLD_01578 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
MIOPJFLD_01579 5.8e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MIOPJFLD_01580 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MIOPJFLD_01581 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MIOPJFLD_01582 5.7e-186 spoVE D Belongs to the SEDS family
MIOPJFLD_01583 6.7e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MIOPJFLD_01584 5.3e-167 murB 1.3.1.98 M cell wall formation
MIOPJFLD_01585 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MIOPJFLD_01586 2.4e-103 ylxW S protein conserved in bacteria
MIOPJFLD_01587 1.8e-91 ylxX S protein conserved in bacteria
MIOPJFLD_01588 6.2e-58 sbp S small basic protein
MIOPJFLD_01589 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MIOPJFLD_01590 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MIOPJFLD_01591 0.0 bpr O COG1404 Subtilisin-like serine proteases
MIOPJFLD_01592 1.7e-171 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MIOPJFLD_01593 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MIOPJFLD_01594 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MIOPJFLD_01595 2.4e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MIOPJFLD_01596 1e-253 argE 3.5.1.16 E Acetylornithine deacetylase
MIOPJFLD_01597 2.4e-37 ylmC S sporulation protein
MIOPJFLD_01598 2e-157 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
MIOPJFLD_01599 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MIOPJFLD_01600 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MIOPJFLD_01601 1.3e-39 yggT S membrane
MIOPJFLD_01602 2e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
MIOPJFLD_01603 2.6e-67 divIVA D Cell division initiation protein
MIOPJFLD_01604 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MIOPJFLD_01605 8.5e-63 dksA T COG1734 DnaK suppressor protein
MIOPJFLD_01606 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MIOPJFLD_01607 4.2e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MIOPJFLD_01608 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MIOPJFLD_01609 5.4e-229 pyrP F Xanthine uracil
MIOPJFLD_01610 3.4e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MIOPJFLD_01611 1.4e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MIOPJFLD_01612 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MIOPJFLD_01613 0.0 carB 6.3.5.5 F Belongs to the CarB family
MIOPJFLD_01614 6.5e-142 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MIOPJFLD_01615 1e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MIOPJFLD_01616 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MIOPJFLD_01617 7.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MIOPJFLD_01619 2.2e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
MIOPJFLD_01620 1.8e-179 cysP P phosphate transporter
MIOPJFLD_01621 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
MIOPJFLD_01622 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
MIOPJFLD_01623 4.1e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
MIOPJFLD_01624 1.4e-144 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
MIOPJFLD_01625 1.6e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
MIOPJFLD_01626 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
MIOPJFLD_01627 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
MIOPJFLD_01628 2.4e-156 yloC S stress-induced protein
MIOPJFLD_01629 1.5e-40 ylzA S Belongs to the UPF0296 family
MIOPJFLD_01630 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MIOPJFLD_01631 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MIOPJFLD_01632 7e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MIOPJFLD_01633 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MIOPJFLD_01634 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MIOPJFLD_01635 9.4e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MIOPJFLD_01636 6e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MIOPJFLD_01637 9e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MIOPJFLD_01638 7.9e-140 stp 3.1.3.16 T phosphatase
MIOPJFLD_01639 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
MIOPJFLD_01640 7.3e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MIOPJFLD_01641 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MIOPJFLD_01642 6.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
MIOPJFLD_01643 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MIOPJFLD_01644 5.5e-59 asp S protein conserved in bacteria
MIOPJFLD_01645 2.3e-301 yloV S kinase related to dihydroxyacetone kinase
MIOPJFLD_01646 9.6e-118 sdaAB 4.3.1.17 E L-serine dehydratase
MIOPJFLD_01647 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
MIOPJFLD_01648 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MIOPJFLD_01649 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MIOPJFLD_01650 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MIOPJFLD_01651 2.9e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MIOPJFLD_01652 6.1e-129 IQ reductase
MIOPJFLD_01653 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MIOPJFLD_01654 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MIOPJFLD_01655 0.0 smc D Required for chromosome condensation and partitioning
MIOPJFLD_01656 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MIOPJFLD_01657 6.4e-87
MIOPJFLD_01658 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MIOPJFLD_01659 3e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MIOPJFLD_01660 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MIOPJFLD_01661 3.8e-35 ylqC S Belongs to the UPF0109 family
MIOPJFLD_01662 6.3e-61 ylqD S YlqD protein
MIOPJFLD_01663 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MIOPJFLD_01664 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MIOPJFLD_01665 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MIOPJFLD_01666 7.9e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MIOPJFLD_01667 1e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MIOPJFLD_01668 1.8e-288 ylqG
MIOPJFLD_01669 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
MIOPJFLD_01670 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MIOPJFLD_01671 3.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MIOPJFLD_01672 4.7e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
MIOPJFLD_01673 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MIOPJFLD_01674 1.6e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MIOPJFLD_01675 2.5e-169 xerC L tyrosine recombinase XerC
MIOPJFLD_01676 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MIOPJFLD_01677 8.5e-241 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MIOPJFLD_01678 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MIOPJFLD_01679 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MIOPJFLD_01680 3.4e-74 flgC N Belongs to the flagella basal body rod proteins family
MIOPJFLD_01681 1.9e-31 fliE N Flagellar hook-basal body
MIOPJFLD_01682 7e-255 fliF N The M ring may be actively involved in energy transduction
MIOPJFLD_01683 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MIOPJFLD_01684 2.2e-105 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
MIOPJFLD_01685 3.6e-241 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MIOPJFLD_01686 1.5e-69 fliJ N Flagellar biosynthesis chaperone
MIOPJFLD_01687 5.5e-35 ylxF S MgtE intracellular N domain
MIOPJFLD_01688 2.5e-195 fliK N Flagellar hook-length control protein
MIOPJFLD_01689 1.7e-72 flgD N Flagellar basal body rod modification protein
MIOPJFLD_01690 8.2e-140 flgG N Flagellar basal body rod
MIOPJFLD_01691 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
MIOPJFLD_01692 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MIOPJFLD_01693 5.9e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MIOPJFLD_01694 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
MIOPJFLD_01695 6e-96 fliZ N Flagellar biosynthesis protein, FliO
MIOPJFLD_01696 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
MIOPJFLD_01697 2.2e-36 fliQ N Role in flagellar biosynthesis
MIOPJFLD_01698 3.6e-132 fliR N Flagellar biosynthetic protein FliR
MIOPJFLD_01699 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MIOPJFLD_01700 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MIOPJFLD_01701 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
MIOPJFLD_01702 2.8e-157 flhG D Belongs to the ParA family
MIOPJFLD_01703 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MIOPJFLD_01704 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
MIOPJFLD_01705 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
MIOPJFLD_01706 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MIOPJFLD_01707 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MIOPJFLD_01708 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MIOPJFLD_01709 4.8e-77 ylxL
MIOPJFLD_01710 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
MIOPJFLD_01711 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MIOPJFLD_01712 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MIOPJFLD_01713 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MIOPJFLD_01714 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MIOPJFLD_01715 7.7e-138 cdsA 2.7.7.41 S Belongs to the CDS family
MIOPJFLD_01716 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MIOPJFLD_01717 1e-224 rasP M zinc metalloprotease
MIOPJFLD_01718 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MIOPJFLD_01719 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MIOPJFLD_01721 4.7e-138 spaB S Lantibiotic dehydratase, C terminus
MIOPJFLD_01722 6.9e-102 spaT V ABC transporter
MIOPJFLD_01723 1.3e-51 spaC2 V PFAM Lanthionine synthetase
MIOPJFLD_01724 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
MIOPJFLD_01725 1.1e-203 nusA K Participates in both transcription termination and antitermination
MIOPJFLD_01726 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
MIOPJFLD_01727 3.1e-47 ylxQ J ribosomal protein
MIOPJFLD_01728 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MIOPJFLD_01729 3.9e-44 ylxP S protein conserved in bacteria
MIOPJFLD_01730 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MIOPJFLD_01731 4.3e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MIOPJFLD_01732 6.7e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MIOPJFLD_01733 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MIOPJFLD_01734 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MIOPJFLD_01735 2.6e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
MIOPJFLD_01736 2.2e-232 pepR S Belongs to the peptidase M16 family
MIOPJFLD_01737 2.6e-42 ymxH S YlmC YmxH family
MIOPJFLD_01738 1.1e-161 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
MIOPJFLD_01739 2.2e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MIOPJFLD_01740 1.9e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MIOPJFLD_01741 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
MIOPJFLD_01742 5.2e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MIOPJFLD_01743 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MIOPJFLD_01744 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
MIOPJFLD_01745 4.4e-32 S YlzJ-like protein
MIOPJFLD_01746 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MIOPJFLD_01747 1.4e-133 ymfC K Transcriptional regulator
MIOPJFLD_01748 3.8e-205 ymfD EGP Major facilitator Superfamily
MIOPJFLD_01749 2.7e-233 ymfF S Peptidase M16
MIOPJFLD_01750 2.4e-242 ymfH S zinc protease
MIOPJFLD_01751 1.7e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
MIOPJFLD_01752 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
MIOPJFLD_01753 2.7e-143 ymfK S Protein of unknown function (DUF3388)
MIOPJFLD_01754 1.9e-124 ymfM S protein conserved in bacteria
MIOPJFLD_01755 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MIOPJFLD_01756 2.1e-235 cinA 3.5.1.42 S Belongs to the CinA family
MIOPJFLD_01757 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MIOPJFLD_01758 9.1e-212 pbpX V Beta-lactamase
MIOPJFLD_01759 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
MIOPJFLD_01760 1.9e-152 ymdB S protein conserved in bacteria
MIOPJFLD_01761 1.2e-36 spoVS S Stage V sporulation protein S
MIOPJFLD_01762 4.3e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
MIOPJFLD_01763 1.2e-216 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MIOPJFLD_01764 1.7e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MIOPJFLD_01765 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
MIOPJFLD_01766 2.2e-88 cotE S Spore coat protein
MIOPJFLD_01767 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MIOPJFLD_01768 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MIOPJFLD_01769 2e-69 S Regulatory protein YrvL
MIOPJFLD_01770 1.8e-96 ymcC S Membrane
MIOPJFLD_01771 2.2e-108 pksA K Transcriptional regulator
MIOPJFLD_01772 3.7e-125 pksB 3.1.2.6 S Polyketide biosynthesis
MIOPJFLD_01773 1.2e-160 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MIOPJFLD_01775 1.6e-182 pksD Q Acyl transferase domain
MIOPJFLD_01776 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MIOPJFLD_01777 1.8e-37 acpK IQ Phosphopantetheine attachment site
MIOPJFLD_01778 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MIOPJFLD_01779 8.7e-245 pksG 2.3.3.10 I synthase
MIOPJFLD_01780 1.3e-142 pksH 4.2.1.18 I enoyl-CoA hydratase
MIOPJFLD_01781 2.6e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
MIOPJFLD_01782 0.0 rhiB IQ polyketide synthase
MIOPJFLD_01783 0.0 pfaA Q Polyketide synthase of type I
MIOPJFLD_01784 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
MIOPJFLD_01785 0.0 dhbF IQ polyketide synthase
MIOPJFLD_01786 0.0 pks13 HQ Beta-ketoacyl synthase
MIOPJFLD_01787 2e-230 cypA C Cytochrome P450
MIOPJFLD_01788 4.9e-60 ymzB
MIOPJFLD_01789 2e-160 ymaE S Metallo-beta-lactamase superfamily
MIOPJFLD_01790 6.6e-251 aprX O Belongs to the peptidase S8 family
MIOPJFLD_01791 1.9e-07 K Transcriptional regulator
MIOPJFLD_01792 1.3e-125 ymaC S Replication protein
MIOPJFLD_01793 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
MIOPJFLD_01794 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
MIOPJFLD_01795 5.4e-50 ebrA P Small Multidrug Resistance protein
MIOPJFLD_01797 2.1e-46 ymaF S YmaF family
MIOPJFLD_01798 2.1e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MIOPJFLD_01799 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MIOPJFLD_01800 8.2e-23
MIOPJFLD_01801 4.5e-22 ymzA
MIOPJFLD_01802 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
MIOPJFLD_01803 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MIOPJFLD_01804 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MIOPJFLD_01805 2e-109 ymaB
MIOPJFLD_01806 1.1e-112 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MIOPJFLD_01807 1.7e-176 spoVK O stage V sporulation protein K
MIOPJFLD_01808 6.7e-229 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MIOPJFLD_01809 1.7e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MIOPJFLD_01810 1.1e-68 glnR K transcriptional
MIOPJFLD_01811 7e-261 glnA 6.3.1.2 E glutamine synthetase
MIOPJFLD_01812 3.8e-10
MIOPJFLD_01813 5.6e-30
MIOPJFLD_01814 8.5e-124
MIOPJFLD_01815 2.1e-36
MIOPJFLD_01816 1.7e-93 G SMI1-KNR4 cell-wall
MIOPJFLD_01817 3.6e-96 ynaD J Acetyltransferase (GNAT) domain
MIOPJFLD_01818 8.1e-122 ynaE S Domain of unknown function (DUF3885)
MIOPJFLD_01819 1.3e-56 ynaF
MIOPJFLD_01821 2.3e-81 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
MIOPJFLD_01822 1.9e-253 xynT G MFS/sugar transport protein
MIOPJFLD_01823 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
MIOPJFLD_01824 2.8e-213 xylR GK ROK family
MIOPJFLD_01825 4.4e-263 xylA 5.3.1.5 G Belongs to the xylose isomerase family
MIOPJFLD_01826 1.3e-290 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
MIOPJFLD_01827 8.2e-39 yokF 3.1.31.1 L RNA catabolic process
MIOPJFLD_01828 6.1e-255 iolT EGP Major facilitator Superfamily
MIOPJFLD_01829 1.7e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MIOPJFLD_01831 2e-82 yncE S Protein of unknown function (DUF2691)
MIOPJFLD_01832 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
MIOPJFLD_01835 3.3e-163 S Thymidylate synthase
MIOPJFLD_01837 6.6e-131 S Domain of unknown function, YrpD
MIOPJFLD_01840 7.9e-25 tatA U protein secretion
MIOPJFLD_01841 1.8e-71
MIOPJFLD_01842 7.5e-79 yndB S Activator of Hsp90 ATPase homolog 1-like protein
MIOPJFLD_01845 1.8e-284 gerAA EG Spore germination protein
MIOPJFLD_01846 2.3e-193 gerAB U Spore germination
MIOPJFLD_01847 2.2e-216 gerLC S Spore germination protein
MIOPJFLD_01848 1.4e-150 yndG S DoxX-like family
MIOPJFLD_01849 5.4e-115 yndH S Domain of unknown function (DUF4166)
MIOPJFLD_01850 5.7e-305 yndJ S YndJ-like protein
MIOPJFLD_01852 6.8e-136 yndL S Replication protein
MIOPJFLD_01853 1.7e-73 yndM S Protein of unknown function (DUF2512)
MIOPJFLD_01854 4.9e-78 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
MIOPJFLD_01855 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MIOPJFLD_01856 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
MIOPJFLD_01857 2.9e-111 yneB L resolvase
MIOPJFLD_01858 1.3e-32 ynzC S UPF0291 protein
MIOPJFLD_01859 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MIOPJFLD_01860 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
MIOPJFLD_01861 1.8e-28 yneF S UPF0154 protein
MIOPJFLD_01862 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
MIOPJFLD_01863 2.3e-125 ccdA O cytochrome c biogenesis protein
MIOPJFLD_01864 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
MIOPJFLD_01865 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
MIOPJFLD_01866 4.2e-74 yneK S Protein of unknown function (DUF2621)
MIOPJFLD_01867 2.2e-63 hspX O Spore coat protein
MIOPJFLD_01868 3.9e-19 sspP S Belongs to the SspP family
MIOPJFLD_01869 2.5e-14 sspO S Belongs to the SspO family
MIOPJFLD_01870 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MIOPJFLD_01871 1e-90 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MIOPJFLD_01873 3.1e-08 sspN S Small acid-soluble spore protein N family
MIOPJFLD_01874 3.9e-35 tlp S Belongs to the Tlp family
MIOPJFLD_01875 1.2e-73 yneP S Thioesterase-like superfamily
MIOPJFLD_01876 2.2e-53 yneQ
MIOPJFLD_01877 4.1e-49 yneR S Belongs to the HesB IscA family
MIOPJFLD_01878 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MIOPJFLD_01879 6.6e-69 yccU S CoA-binding protein
MIOPJFLD_01880 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MIOPJFLD_01881 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MIOPJFLD_01882 2.3e-12
MIOPJFLD_01883 1.5e-56 ynfC
MIOPJFLD_01884 1.8e-251 agcS E Sodium alanine symporter
MIOPJFLD_01885 1.2e-293 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
MIOPJFLD_01887 5.3e-250 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
MIOPJFLD_01888 8.4e-290 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
MIOPJFLD_01889 2e-79 yngA S membrane
MIOPJFLD_01890 3.5e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MIOPJFLD_01891 5.5e-104 yngC S membrane-associated protein
MIOPJFLD_01892 3.6e-232 nrnB S phosphohydrolase (DHH superfamily)
MIOPJFLD_01893 5.9e-288 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MIOPJFLD_01894 7.1e-136 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
MIOPJFLD_01895 3.4e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
MIOPJFLD_01896 1.5e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
MIOPJFLD_01897 4.7e-249 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
MIOPJFLD_01898 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MIOPJFLD_01899 2.8e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
MIOPJFLD_01900 1.5e-302 yngK T Glycosyl hydrolase-like 10
MIOPJFLD_01901 3.1e-63 yngL S Protein of unknown function (DUF1360)
MIOPJFLD_01902 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
MIOPJFLD_01903 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MIOPJFLD_01904 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MIOPJFLD_01905 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MIOPJFLD_01906 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MIOPJFLD_01907 1.7e-271 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
MIOPJFLD_01908 4.2e-186 yoxA 5.1.3.3 G Aldose 1-epimerase
MIOPJFLD_01909 2.3e-246 yoeA V MATE efflux family protein
MIOPJFLD_01910 4.1e-98 yoeB S IseA DL-endopeptidase inhibitor
MIOPJFLD_01912 2.2e-96 L Integrase
MIOPJFLD_01913 8.7e-34 yoeD G Helix-turn-helix domain
MIOPJFLD_01914 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
MIOPJFLD_01915 6.3e-154 gltR1 K Transcriptional regulator
MIOPJFLD_01916 2.4e-113 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MIOPJFLD_01917 2e-58 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MIOPJFLD_01918 5e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MIOPJFLD_01919 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
MIOPJFLD_01920 7.8e-155 gltC K Transcriptional regulator
MIOPJFLD_01921 1.5e-203 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MIOPJFLD_01922 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MIOPJFLD_01923 2.5e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
MIOPJFLD_01924 3.7e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MIOPJFLD_01925 9.2e-39 yoxC S Bacterial protein of unknown function (DUF948)
MIOPJFLD_01926 8e-132 yoxB
MIOPJFLD_01927 2.9e-96 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MIOPJFLD_01928 1.1e-125 V ABC-2 family transporter protein
MIOPJFLD_01929 6.4e-94 V ABC-2 family transporter protein
MIOPJFLD_01930 4.8e-139 V AAA domain, putative AbiEii toxin, Type IV TA system
MIOPJFLD_01931 6.6e-80 hpr K helix_turn_helix multiple antibiotic resistance protein
MIOPJFLD_01932 1.5e-233 yoaB EGP Major facilitator Superfamily
MIOPJFLD_01933 1e-276 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
MIOPJFLD_01934 2.9e-182 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MIOPJFLD_01935 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MIOPJFLD_01936 8.7e-32 yoaF
MIOPJFLD_01937 1.5e-171 iolT EGP Major facilitator Superfamily
MIOPJFLD_01938 1.4e-204 S Oxidoreductase family, C-terminal alpha/beta domain
MIOPJFLD_01939 3.2e-151 iolE 4.2.1.44 G Xylose isomerase-like TIM barrel
MIOPJFLD_01940 3.3e-90 purR K Transcriptional regulator
MIOPJFLD_01941 2.2e-07
MIOPJFLD_01942 7e-14
MIOPJFLD_01943 7.7e-35 S Protein of unknown function (DUF4025)
MIOPJFLD_01944 3.8e-179 mcpU NT methyl-accepting chemotaxis protein
MIOPJFLD_01945 2.1e-279 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
MIOPJFLD_01946 3.2e-132 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
MIOPJFLD_01947 2.3e-111 yoaK S Membrane
MIOPJFLD_01948 1.4e-195 pelB 4.2.2.10, 4.2.2.2 G Amb_all
MIOPJFLD_01949 4.6e-131 yoqW S Belongs to the SOS response-associated peptidase family
MIOPJFLD_01952 2.1e-232 oxdC 4.1.1.2 G Oxalate decarboxylase
MIOPJFLD_01955 5e-87
MIOPJFLD_01956 7.1e-172 yoaR V vancomycin resistance protein
MIOPJFLD_01957 7.3e-75 yoaS S Protein of unknown function (DUF2975)
MIOPJFLD_01958 4.4e-30 yozG K Transcriptional regulator
MIOPJFLD_01959 6.3e-148 yoaT S Protein of unknown function (DUF817)
MIOPJFLD_01960 8.6e-159 yoaU K LysR substrate binding domain
MIOPJFLD_01961 1.8e-159 yijE EG EamA-like transporter family
MIOPJFLD_01962 1.8e-77 yoaW
MIOPJFLD_01963 7.3e-115 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
MIOPJFLD_01964 2.2e-168 bla 3.5.2.6 V beta-lactamase
MIOPJFLD_01967 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
MIOPJFLD_01968 4e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
MIOPJFLD_01969 8.8e-37 S TM2 domain
MIOPJFLD_01973 1.1e-116
MIOPJFLD_01975 8.9e-65 yoaQ S Evidence 4 Homologs of previously reported genes of
MIOPJFLD_01976 1.8e-33 yoqW S Belongs to the SOS response-associated peptidase family
MIOPJFLD_01978 4e-100 S aspartate phosphatase
MIOPJFLD_01980 6.9e-19
MIOPJFLD_01981 3.3e-28 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MIOPJFLD_01982 1.4e-17 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MIOPJFLD_01983 1.2e-100 yokH G SMI1 / KNR4 family
MIOPJFLD_01984 2.2e-276 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
MIOPJFLD_01985 9.3e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
MIOPJFLD_01986 2.3e-133 yobQ K helix_turn_helix, arabinose operon control protein
MIOPJFLD_01987 4.6e-137 yobR 2.3.1.1 J FR47-like protein
MIOPJFLD_01988 3.3e-98 yobS K Transcriptional regulator
MIOPJFLD_01989 1.4e-130 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
MIOPJFLD_01990 8.3e-87 yobU K Bacterial transcription activator, effector binding domain
MIOPJFLD_01991 2.1e-171 yobV K WYL domain
MIOPJFLD_01992 1e-93 yobW
MIOPJFLD_01993 1e-51 czrA K transcriptional
MIOPJFLD_01994 8.3e-117 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MIOPJFLD_01995 1.5e-92 yozB S membrane
MIOPJFLD_01996 6.4e-145
MIOPJFLD_01997 2.5e-94 yocC
MIOPJFLD_01998 9.3e-186 yocD 3.4.17.13 V peptidase S66
MIOPJFLD_01999 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
MIOPJFLD_02000 4.6e-197 desK 2.7.13.3 T Histidine kinase
MIOPJFLD_02001 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MIOPJFLD_02002 6e-112 yocH CBM50 M COG1388 FOG LysM repeat
MIOPJFLD_02003 0.0 recQ 3.6.4.12 L DNA helicase
MIOPJFLD_02004 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MIOPJFLD_02005 7.4e-83 dksA T general stress protein
MIOPJFLD_02006 8.4e-54 yocL
MIOPJFLD_02007 2e-30
MIOPJFLD_02008 6.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
MIOPJFLD_02009 1.1e-40 yozN
MIOPJFLD_02010 1.9e-36 yocN
MIOPJFLD_02011 4.2e-56 yozO S Bacterial PH domain
MIOPJFLD_02012 2.7e-31 yozC
MIOPJFLD_02013 5.2e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
MIOPJFLD_02014 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
MIOPJFLD_02015 1.3e-164 sodA 1.15.1.1 P Superoxide dismutase
MIOPJFLD_02016 3.4e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MIOPJFLD_02017 5.1e-168 yocS S -transporter
MIOPJFLD_02018 5.3e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MIOPJFLD_02019 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MIOPJFLD_02020 0.0 yojO P Von Willebrand factor
MIOPJFLD_02021 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
MIOPJFLD_02022 1e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MIOPJFLD_02023 2.1e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MIOPJFLD_02024 2.6e-230 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
MIOPJFLD_02025 2.2e-108 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MIOPJFLD_02027 1.6e-244 norM V Multidrug efflux pump
MIOPJFLD_02028 3.2e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MIOPJFLD_02029 3.7e-125 yojG S deacetylase
MIOPJFLD_02030 2.2e-60 yojF S Protein of unknown function (DUF1806)
MIOPJFLD_02031 1.5e-43
MIOPJFLD_02032 1.9e-161 rarD S -transporter
MIOPJFLD_02033 8.6e-65 yozR S COG0071 Molecular chaperone (small heat shock protein)
MIOPJFLD_02034 2.6e-09
MIOPJFLD_02035 7.9e-204 gntP EG COG2610 H gluconate symporter and related permeases
MIOPJFLD_02036 4.7e-64 yodA S tautomerase
MIOPJFLD_02037 4.4e-55 yodB K transcriptional
MIOPJFLD_02038 1.4e-107 yodC C nitroreductase
MIOPJFLD_02039 4.6e-111 mhqD S Carboxylesterase
MIOPJFLD_02040 5.5e-172 yodE E COG0346 Lactoylglutathione lyase and related lyases
MIOPJFLD_02041 6.2e-28 S Protein of unknown function (DUF3311)
MIOPJFLD_02042 1.2e-269 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MIOPJFLD_02043 9.7e-253 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
MIOPJFLD_02044 6.3e-128 yodH Q Methyltransferase
MIOPJFLD_02045 1.5e-23 yodI
MIOPJFLD_02046 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
MIOPJFLD_02047 4.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
MIOPJFLD_02048 5.3e-09
MIOPJFLD_02049 1.4e-53 yodL S YodL-like
MIOPJFLD_02050 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
MIOPJFLD_02051 2.8e-24 yozD S YozD-like protein
MIOPJFLD_02053 6e-123 yodN
MIOPJFLD_02054 1.4e-36 yozE S Belongs to the UPF0346 family
MIOPJFLD_02055 2.9e-47 yokU S YokU-like protein, putative antitoxin
MIOPJFLD_02056 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
MIOPJFLD_02057 5.1e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
MIOPJFLD_02058 3.2e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
MIOPJFLD_02059 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MIOPJFLD_02060 6.5e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MIOPJFLD_02061 1.3e-246 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MIOPJFLD_02063 5.9e-143 yiiD K acetyltransferase
MIOPJFLD_02064 1e-253 cgeD M maturation of the outermost layer of the spore
MIOPJFLD_02065 2e-09 cgeC
MIOPJFLD_02066 8.4e-18 cgeC
MIOPJFLD_02067 3.1e-63 cgeA
MIOPJFLD_02068 2.2e-176 cgeB S Spore maturation protein
MIOPJFLD_02069 6.4e-210 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
MIOPJFLD_02070 5.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
MIOPJFLD_02071 3.7e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MIOPJFLD_02072 1.7e-101 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MIOPJFLD_02073 1.6e-70 ypoP K transcriptional
MIOPJFLD_02074 5.8e-223 mepA V MATE efflux family protein
MIOPJFLD_02075 1.4e-26 ypmT S Uncharacterized ympT
MIOPJFLD_02076 7.2e-98 ypmS S protein conserved in bacteria
MIOPJFLD_02077 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
MIOPJFLD_02078 1.5e-106 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MIOPJFLD_02079 3.4e-39 ypmP S Protein of unknown function (DUF2535)
MIOPJFLD_02080 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MIOPJFLD_02081 1.6e-185 pspF K Transcriptional regulator
MIOPJFLD_02082 4.2e-110 hlyIII S protein, Hemolysin III
MIOPJFLD_02083 5.8e-109 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MIOPJFLD_02084 4.8e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MIOPJFLD_02085 7.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
MIOPJFLD_02086 7.8e-114 ypjP S YpjP-like protein
MIOPJFLD_02087 6.3e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
MIOPJFLD_02088 1.7e-75 yphP S Belongs to the UPF0403 family
MIOPJFLD_02089 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
MIOPJFLD_02090 6.4e-154 ypgR C COG0694 Thioredoxin-like proteins and domains
MIOPJFLD_02091 2.9e-108 ypgQ S phosphohydrolase
MIOPJFLD_02092 2.8e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
MIOPJFLD_02093 1.4e-175 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MIOPJFLD_02094 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
MIOPJFLD_02095 1e-30 cspD K Cold-shock protein
MIOPJFLD_02096 3.8e-16 degR
MIOPJFLD_02097 8.1e-31 S Protein of unknown function (DUF2564)
MIOPJFLD_02098 2.6e-27 ypeQ S Zinc-finger
MIOPJFLD_02099 6.4e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
MIOPJFLD_02100 2.9e-105 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MIOPJFLD_02101 2.7e-67 rnhA 3.1.26.4 L Ribonuclease
MIOPJFLD_02103 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
MIOPJFLD_02104 2e-07
MIOPJFLD_02105 1e-38 ypbS S Protein of unknown function (DUF2533)
MIOPJFLD_02106 0.0 ypbR S Dynamin family
MIOPJFLD_02107 5.1e-87 ypbQ S protein conserved in bacteria
MIOPJFLD_02108 2.8e-207 bcsA Q Naringenin-chalcone synthase
MIOPJFLD_02109 9.5e-226 pbuX F xanthine
MIOPJFLD_02110 2.2e-97 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MIOPJFLD_02111 3.3e-291 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MIOPJFLD_02112 1.5e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
MIOPJFLD_02113 4.3e-101 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
MIOPJFLD_02114 8.4e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
MIOPJFLD_02115 1.5e-186 ptxS K transcriptional
MIOPJFLD_02116 1.4e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MIOPJFLD_02117 5.1e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIOPJFLD_02118 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
MIOPJFLD_02120 1.6e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MIOPJFLD_02121 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MIOPJFLD_02122 6.3e-91 ypsA S Belongs to the UPF0398 family
MIOPJFLD_02123 8.1e-235 yprB L RNase_H superfamily
MIOPJFLD_02124 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MIOPJFLD_02125 2.3e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
MIOPJFLD_02126 3.6e-70 hspX O Belongs to the small heat shock protein (HSP20) family
MIOPJFLD_02127 1.2e-48 yppG S YppG-like protein
MIOPJFLD_02129 1.5e-11 yppE S Bacterial domain of unknown function (DUF1798)
MIOPJFLD_02132 2.9e-184 yppC S Protein of unknown function (DUF2515)
MIOPJFLD_02133 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MIOPJFLD_02134 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
MIOPJFLD_02135 2.3e-92 ypoC
MIOPJFLD_02136 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MIOPJFLD_02137 5.7e-129 dnaD L DNA replication protein DnaD
MIOPJFLD_02138 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
MIOPJFLD_02139 1.3e-221 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
MIOPJFLD_02140 2.2e-79 ypmB S protein conserved in bacteria
MIOPJFLD_02141 6.7e-23 ypmA S Protein of unknown function (DUF4264)
MIOPJFLD_02142 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MIOPJFLD_02143 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MIOPJFLD_02144 4.7e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MIOPJFLD_02145 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MIOPJFLD_02146 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MIOPJFLD_02147 6.6e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MIOPJFLD_02148 5.3e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
MIOPJFLD_02149 4.5e-129 bshB1 S proteins, LmbE homologs
MIOPJFLD_02150 7.9e-70 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
MIOPJFLD_02151 4.5e-146 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MIOPJFLD_02152 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
MIOPJFLD_02153 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
MIOPJFLD_02154 6.1e-143 ypjB S sporulation protein
MIOPJFLD_02155 4.4e-98 ypjA S membrane
MIOPJFLD_02156 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
MIOPJFLD_02157 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
MIOPJFLD_02158 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
MIOPJFLD_02159 4.2e-77 ypiF S Protein of unknown function (DUF2487)
MIOPJFLD_02160 1.1e-98 ypiB S Belongs to the UPF0302 family
MIOPJFLD_02161 4.1e-234 S COG0457 FOG TPR repeat
MIOPJFLD_02162 8.9e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MIOPJFLD_02163 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
MIOPJFLD_02164 1.4e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MIOPJFLD_02165 5.2e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MIOPJFLD_02166 6.4e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MIOPJFLD_02167 3.3e-115 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
MIOPJFLD_02168 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
MIOPJFLD_02169 1.4e-179 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MIOPJFLD_02170 7.6e-291 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MIOPJFLD_02171 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
MIOPJFLD_02172 5.8e-205 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MIOPJFLD_02173 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MIOPJFLD_02174 1.1e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
MIOPJFLD_02175 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MIOPJFLD_02176 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MIOPJFLD_02177 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MIOPJFLD_02178 2.8e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
MIOPJFLD_02179 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MIOPJFLD_02180 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
MIOPJFLD_02181 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MIOPJFLD_02182 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MIOPJFLD_02183 1.5e-135 yphF
MIOPJFLD_02184 1.6e-18 yphE S Protein of unknown function (DUF2768)
MIOPJFLD_02185 5.6e-181 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MIOPJFLD_02186 1.5e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MIOPJFLD_02187 2.3e-27 ypzH
MIOPJFLD_02188 2.5e-161 seaA S YIEGIA protein
MIOPJFLD_02189 1.3e-102 yphA
MIOPJFLD_02190 1e-07 S YpzI-like protein
MIOPJFLD_02191 1.2e-183 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MIOPJFLD_02192 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
MIOPJFLD_02193 1.2e-110 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MIOPJFLD_02194 5e-21 S Family of unknown function (DUF5359)
MIOPJFLD_02195 6.6e-111 ypfA M Flagellar protein YcgR
MIOPJFLD_02196 1.9e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
MIOPJFLD_02197 3.3e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
MIOPJFLD_02198 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
MIOPJFLD_02199 1.3e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
MIOPJFLD_02200 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
MIOPJFLD_02201 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MIOPJFLD_02202 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
MIOPJFLD_02203 2.8e-81 ypbF S Protein of unknown function (DUF2663)
MIOPJFLD_02204 1.7e-78 ypbE M Lysin motif
MIOPJFLD_02205 1.1e-99 ypbD S metal-dependent membrane protease
MIOPJFLD_02206 9.2e-286 recQ 3.6.4.12 L DNA helicase
MIOPJFLD_02207 1.8e-198 ypbB 5.1.3.1 S protein conserved in bacteria
MIOPJFLD_02208 4.7e-41 fer C Ferredoxin
MIOPJFLD_02209 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MIOPJFLD_02210 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MIOPJFLD_02211 2.5e-133 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MIOPJFLD_02212 1.5e-184 rsiX
MIOPJFLD_02213 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
MIOPJFLD_02214 0.0 resE 2.7.13.3 T Histidine kinase
MIOPJFLD_02215 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MIOPJFLD_02216 8.8e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MIOPJFLD_02217 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
MIOPJFLD_02218 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MIOPJFLD_02219 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MIOPJFLD_02220 1.9e-87 spmB S Spore maturation protein
MIOPJFLD_02221 3.5e-103 spmA S Spore maturation protein
MIOPJFLD_02222 8.9e-212 dacB 3.4.16.4 M Belongs to the peptidase S11 family
MIOPJFLD_02223 7.6e-97 ypuI S Protein of unknown function (DUF3907)
MIOPJFLD_02224 2.1e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MIOPJFLD_02225 1.3e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MIOPJFLD_02226 9.4e-92 ypuF S Domain of unknown function (DUF309)
MIOPJFLD_02227 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MIOPJFLD_02228 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MIOPJFLD_02229 7e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MIOPJFLD_02230 3.3e-115 ribE 2.5.1.9 H Riboflavin synthase
MIOPJFLD_02231 8.4e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MIOPJFLD_02232 7.8e-55 ypuD
MIOPJFLD_02233 4e-93 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MIOPJFLD_02234 9.8e-14 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
MIOPJFLD_02236 0.0 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MIOPJFLD_02238 2.5e-77 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MIOPJFLD_02241 5e-93 ntd 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
MIOPJFLD_02245 4.1e-09 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
MIOPJFLD_02246 3e-77 DR0488 T 3D domain protein
MIOPJFLD_02249 2.1e-89 2.7.1.24 H dephospho-CoA kinase activity
MIOPJFLD_02250 1.2e-57 K Cro/C1-type HTH DNA-binding domain
MIOPJFLD_02252 8.6e-09
MIOPJFLD_02255 4.5e-43 ligA 6.5.1.2 L NAD-dependent DNA ligase adenylation domain
MIOPJFLD_02256 1.6e-35
MIOPJFLD_02258 0.0 L 3'-5' exonuclease
MIOPJFLD_02260 8.5e-21 S PQ loop repeat
MIOPJFLD_02261 9.2e-113 dak 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
MIOPJFLD_02263 1.1e-90 tdk 2.7.1.21 F thymidine kinase
MIOPJFLD_02264 6.9e-151 L RNA ligase
MIOPJFLD_02266 2e-83 ruvC 3.1.22.4 L Crossover junction endodeoxyribonuclease RuvC
MIOPJFLD_02267 1.7e-170
MIOPJFLD_02271 3.6e-123
MIOPJFLD_02275 3.7e-179 L Toprim-like
MIOPJFLD_02277 3.3e-244 3.6.4.12 L AAA domain
MIOPJFLD_02278 2.5e-141 dnaI L DNA-dependent DNA replication
MIOPJFLD_02279 2.5e-136 K Helix-turn-helix domain
MIOPJFLD_02280 3.9e-126 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MIOPJFLD_02281 6.6e-67 S phage lysis holin
MIOPJFLD_02283 0.0 3.2.1.4, 3.2.1.78 GH26,GH5,GH9 L Phage minor structural protein
MIOPJFLD_02284 7.4e-300 S Phage tail protein
MIOPJFLD_02285 7.5e-196 D minor tail protein
MIOPJFLD_02287 9.2e-44
MIOPJFLD_02288 7.4e-69 lmaA S Phage tail tube protein
MIOPJFLD_02290 3.6e-57
MIOPJFLD_02291 7.3e-50
MIOPJFLD_02292 4.4e-74
MIOPJFLD_02294 9.5e-150
MIOPJFLD_02295 9.9e-07
MIOPJFLD_02297 1.3e-152 S Phage minor capsid protein 2
MIOPJFLD_02298 5.4e-273 S Phage portal protein, SPP1 Gp6-like
MIOPJFLD_02299 0.0 S TIGRFAM Phage
MIOPJFLD_02300 7.9e-124 L resolvase
MIOPJFLD_02301 5.6e-128
MIOPJFLD_02302 1.2e-62
MIOPJFLD_02305 1.2e-11 S Helix-turn-helix of insertion element transposase
MIOPJFLD_02309 1.8e-12 K PFAM Uncharacterised protein family UPF0150
MIOPJFLD_02310 4.1e-08 N HicA toxin of bacterial toxin-antitoxin,
MIOPJFLD_02311 1.2e-165 S Tetratricopeptide repeat
MIOPJFLD_02313 3.1e-42 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MIOPJFLD_02314 8.1e-149 ypuA S Secreted protein
MIOPJFLD_02315 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MIOPJFLD_02316 1.4e-273 spoVAF EG Stage V sporulation protein AF
MIOPJFLD_02317 1.4e-110 spoVAEA S stage V sporulation protein
MIOPJFLD_02318 2.2e-57 spoVAEB S stage V sporulation protein
MIOPJFLD_02319 9e-192 spoVAD I Stage V sporulation protein AD
MIOPJFLD_02320 2.3e-78 spoVAC S stage V sporulation protein AC
MIOPJFLD_02321 1e-67 spoVAB S Stage V sporulation protein AB
MIOPJFLD_02322 9.6e-112 spoVAA S Stage V sporulation protein AA
MIOPJFLD_02323 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MIOPJFLD_02324 2.3e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MIOPJFLD_02325 5e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
MIOPJFLD_02326 1.1e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
MIOPJFLD_02327 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MIOPJFLD_02328 8.8e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
MIOPJFLD_02329 5.7e-166 xerD L recombinase XerD
MIOPJFLD_02330 3.7e-37 S Protein of unknown function (DUF4227)
MIOPJFLD_02331 2.4e-80 fur P Belongs to the Fur family
MIOPJFLD_02332 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MIOPJFLD_02333 5.5e-30 yqkK
MIOPJFLD_02334 5.5e-242 mleA 1.1.1.38 C malic enzyme
MIOPJFLD_02335 9.1e-235 mleN C Na H antiporter
MIOPJFLD_02336 4.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
MIOPJFLD_02337 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
MIOPJFLD_02338 4.5e-58 ansR K Transcriptional regulator
MIOPJFLD_02339 5.3e-220 yqxK 3.6.4.12 L DNA helicase
MIOPJFLD_02340 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
MIOPJFLD_02342 9.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
MIOPJFLD_02343 3.1e-12 yqkE S Protein of unknown function (DUF3886)
MIOPJFLD_02344 3.9e-170 yqkD S COG1073 Hydrolases of the alpha beta superfamily
MIOPJFLD_02345 4.6e-38 yqkC S Protein of unknown function (DUF2552)
MIOPJFLD_02346 2.8e-54 yqkB S Belongs to the HesB IscA family
MIOPJFLD_02347 3.7e-193 yqkA K GrpB protein
MIOPJFLD_02348 1.8e-59 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
MIOPJFLD_02349 3.6e-87 yqjY K acetyltransferase
MIOPJFLD_02350 1.7e-49 S YolD-like protein
MIOPJFLD_02351 4.5e-238 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MIOPJFLD_02353 2.9e-224 yqjV G Major Facilitator Superfamily
MIOPJFLD_02355 3e-71 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MIOPJFLD_02356 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
MIOPJFLD_02357 5.6e-258 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
MIOPJFLD_02358 2.3e-142 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
MIOPJFLD_02359 2.2e-179 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
MIOPJFLD_02360 1.5e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MIOPJFLD_02361 0.0 rocB E arginine degradation protein
MIOPJFLD_02362 1.8e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MIOPJFLD_02363 1.8e-144 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MIOPJFLD_02364 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MIOPJFLD_02365 1.1e-172 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MIOPJFLD_02366 5.2e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MIOPJFLD_02367 2.6e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MIOPJFLD_02368 4.2e-231 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MIOPJFLD_02369 4.5e-24 yqzJ
MIOPJFLD_02370 3.2e-139 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MIOPJFLD_02371 4.6e-137 yqjF S Uncharacterized conserved protein (COG2071)
MIOPJFLD_02372 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
MIOPJFLD_02373 2.3e-287 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MIOPJFLD_02374 1.9e-71 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
MIOPJFLD_02376 5.2e-98 yqjB S protein conserved in bacteria
MIOPJFLD_02377 1.2e-172 yqjA S Putative aromatic acid exporter C-terminal domain
MIOPJFLD_02378 2.2e-128 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MIOPJFLD_02379 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
MIOPJFLD_02380 4.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
MIOPJFLD_02381 9.3e-77 yqiW S Belongs to the UPF0403 family
MIOPJFLD_02382 9.8e-166 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MIOPJFLD_02383 7.9e-208 norA EGP Major facilitator Superfamily
MIOPJFLD_02384 7.5e-152 bmrR K helix_turn_helix, mercury resistance
MIOPJFLD_02385 1.1e-218 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MIOPJFLD_02386 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MIOPJFLD_02387 6.1e-185 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MIOPJFLD_02388 1.3e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MIOPJFLD_02389 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
MIOPJFLD_02390 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
MIOPJFLD_02391 2.1e-155 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
MIOPJFLD_02392 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
MIOPJFLD_02393 4e-34 yqzF S Protein of unknown function (DUF2627)
MIOPJFLD_02394 7.1e-164 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MIOPJFLD_02395 1.2e-274 prpD 4.2.1.79 S 2-methylcitrate dehydratase
MIOPJFLD_02396 5.4e-206 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
MIOPJFLD_02397 2e-211 mmgC I acyl-CoA dehydrogenase
MIOPJFLD_02398 8.3e-154 hbdA 1.1.1.157 I Dehydrogenase
MIOPJFLD_02399 1.9e-217 mmgA 2.3.1.9 I Belongs to the thiolase family
MIOPJFLD_02400 4.1e-130 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MIOPJFLD_02401 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
MIOPJFLD_02402 5.9e-27
MIOPJFLD_02403 3.6e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
MIOPJFLD_02405 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MIOPJFLD_02406 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
MIOPJFLD_02407 0.0 recN L May be involved in recombinational repair of damaged DNA
MIOPJFLD_02408 1.7e-78 argR K Regulates arginine biosynthesis genes
MIOPJFLD_02409 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
MIOPJFLD_02410 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MIOPJFLD_02411 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MIOPJFLD_02412 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MIOPJFLD_02413 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MIOPJFLD_02414 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MIOPJFLD_02415 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MIOPJFLD_02416 2.1e-67 yqhY S protein conserved in bacteria
MIOPJFLD_02417 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MIOPJFLD_02418 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MIOPJFLD_02419 9.9e-91 spoIIIAH S SpoIIIAH-like protein
MIOPJFLD_02420 2.2e-109 spoIIIAG S stage III sporulation protein AG
MIOPJFLD_02421 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
MIOPJFLD_02422 1.3e-197 spoIIIAE S stage III sporulation protein AE
MIOPJFLD_02423 2.3e-58 spoIIIAD S Stage III sporulation protein AD
MIOPJFLD_02424 7.6e-29 spoIIIAC S stage III sporulation protein AC
MIOPJFLD_02425 4.1e-84 spoIIIAB S Stage III sporulation protein
MIOPJFLD_02426 4e-170 spoIIIAA S stage III sporulation protein AA
MIOPJFLD_02427 7.9e-37 yqhV S Protein of unknown function (DUF2619)
MIOPJFLD_02428 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MIOPJFLD_02429 4.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
MIOPJFLD_02430 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
MIOPJFLD_02431 2.3e-93 yqhR S Conserved membrane protein YqhR
MIOPJFLD_02432 3e-173 yqhQ S Protein of unknown function (DUF1385)
MIOPJFLD_02433 2.2e-61 yqhP
MIOPJFLD_02434 3.4e-163 yqhO S esterase of the alpha-beta hydrolase superfamily
MIOPJFLD_02435 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MIOPJFLD_02436 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MIOPJFLD_02437 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
MIOPJFLD_02438 1.5e-285 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MIOPJFLD_02439 1.4e-253 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MIOPJFLD_02440 9e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
MIOPJFLD_02441 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
MIOPJFLD_02442 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
MIOPJFLD_02443 1.2e-24 sinI S Anti-repressor SinI
MIOPJFLD_02444 1e-54 sinR K transcriptional
MIOPJFLD_02445 1.2e-140 tasA S Cell division protein FtsN
MIOPJFLD_02446 6.7e-59 sipW 3.4.21.89 U Signal peptidase
MIOPJFLD_02447 2.7e-116 yqxM
MIOPJFLD_02448 7.3e-54 yqzG S Protein of unknown function (DUF3889)
MIOPJFLD_02449 1.4e-26 yqzE S YqzE-like protein
MIOPJFLD_02450 4e-44 S ComG operon protein 7
MIOPJFLD_02451 2.9e-34 comGF U Putative Competence protein ComGF
MIOPJFLD_02452 1.1e-59 comGE
MIOPJFLD_02453 4.4e-71 gspH NU protein transport across the cell outer membrane
MIOPJFLD_02454 1.4e-47 comGC U Required for transformation and DNA binding
MIOPJFLD_02455 1.3e-174 comGB NU COG1459 Type II secretory pathway, component PulF
MIOPJFLD_02456 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MIOPJFLD_02457 4e-173 corA P Mg2 transporter protein
MIOPJFLD_02458 3.4e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MIOPJFLD_02459 5.4e-150 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MIOPJFLD_02461 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
MIOPJFLD_02462 1.8e-37 yqgY S Protein of unknown function (DUF2626)
MIOPJFLD_02463 7.3e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
MIOPJFLD_02464 8.9e-23 yqgW S Protein of unknown function (DUF2759)
MIOPJFLD_02465 6.9e-50 yqgV S Thiamine-binding protein
MIOPJFLD_02466 2.7e-199 yqgU
MIOPJFLD_02467 2.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
MIOPJFLD_02468 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MIOPJFLD_02469 3.4e-180 glcK 2.7.1.2 G Glucokinase
MIOPJFLD_02470 3.1e-33 yqgQ S Protein conserved in bacteria
MIOPJFLD_02471 5.7e-267 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
MIOPJFLD_02472 2.5e-09 yqgO
MIOPJFLD_02473 2.5e-103 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MIOPJFLD_02474 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MIOPJFLD_02475 2.7e-197 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
MIOPJFLD_02477 9.2e-51 yqzD
MIOPJFLD_02478 7.3e-72 yqzC S YceG-like family
MIOPJFLD_02479 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MIOPJFLD_02480 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MIOPJFLD_02481 4.4e-158 pstA P Phosphate transport system permease
MIOPJFLD_02482 7.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
MIOPJFLD_02483 3.4e-150 pstS P Phosphate
MIOPJFLD_02484 0.0 pbpA 3.4.16.4 M penicillin-binding protein
MIOPJFLD_02485 2.5e-231 yqgE EGP Major facilitator superfamily
MIOPJFLD_02486 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
MIOPJFLD_02487 4e-73 yqgC S protein conserved in bacteria
MIOPJFLD_02488 3.9e-131 yqgB S Protein of unknown function (DUF1189)
MIOPJFLD_02489 5.2e-47 yqfZ M LysM domain
MIOPJFLD_02490 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MIOPJFLD_02491 2.8e-61 yqfX S membrane
MIOPJFLD_02492 7.9e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
MIOPJFLD_02493 1.9e-77 zur P Belongs to the Fur family
MIOPJFLD_02494 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
MIOPJFLD_02495 2.1e-36 yqfT S Protein of unknown function (DUF2624)
MIOPJFLD_02496 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MIOPJFLD_02497 2.9e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MIOPJFLD_02498 2.9e-14 yqfQ S YqfQ-like protein
MIOPJFLD_02499 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MIOPJFLD_02500 4.8e-210 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MIOPJFLD_02501 1.4e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
MIOPJFLD_02502 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
MIOPJFLD_02503 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MIOPJFLD_02504 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MIOPJFLD_02505 4.5e-88 yaiI S Belongs to the UPF0178 family
MIOPJFLD_02506 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MIOPJFLD_02507 4.5e-112 ccpN K CBS domain
MIOPJFLD_02508 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MIOPJFLD_02509 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MIOPJFLD_02510 1.8e-144 recO L Involved in DNA repair and RecF pathway recombination
MIOPJFLD_02511 8.4e-19 S YqzL-like protein
MIOPJFLD_02512 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MIOPJFLD_02513 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MIOPJFLD_02514 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MIOPJFLD_02515 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MIOPJFLD_02516 0.0 yqfF S membrane-associated HD superfamily hydrolase
MIOPJFLD_02518 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
MIOPJFLD_02519 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
MIOPJFLD_02520 2.7e-45 yqfC S sporulation protein YqfC
MIOPJFLD_02521 3.7e-22 yqfB
MIOPJFLD_02522 4.3e-122 yqfA S UPF0365 protein
MIOPJFLD_02523 1.7e-227 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
MIOPJFLD_02524 2.5e-61 yqeY S Yqey-like protein
MIOPJFLD_02525 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MIOPJFLD_02526 4.1e-157 yqeW P COG1283 Na phosphate symporter
MIOPJFLD_02527 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
MIOPJFLD_02528 2.1e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MIOPJFLD_02529 4.6e-174 prmA J Methylates ribosomal protein L11
MIOPJFLD_02530 3.6e-181 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MIOPJFLD_02531 0.0 dnaK O Heat shock 70 kDa protein
MIOPJFLD_02532 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MIOPJFLD_02533 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MIOPJFLD_02534 2.9e-215 hemN H Involved in the biosynthesis of porphyrin-containing compound
MIOPJFLD_02535 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MIOPJFLD_02536 3.6e-52 yqxA S Protein of unknown function (DUF3679)
MIOPJFLD_02537 1.5e-222 spoIIP M stage II sporulation protein P
MIOPJFLD_02538 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MIOPJFLD_02539 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
MIOPJFLD_02540 9.6e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
MIOPJFLD_02541 0.0 comEC S Competence protein ComEC
MIOPJFLD_02542 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
MIOPJFLD_02543 6.2e-103 wza L COG1555 DNA uptake protein and related DNA-binding proteins
MIOPJFLD_02544 2.1e-146 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MIOPJFLD_02545 1.1e-138 yqeM Q Methyltransferase
MIOPJFLD_02546 1.3e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MIOPJFLD_02547 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
MIOPJFLD_02548 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MIOPJFLD_02549 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
MIOPJFLD_02550 1.7e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MIOPJFLD_02551 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MIOPJFLD_02552 5.3e-95 yqeG S hydrolase of the HAD superfamily
MIOPJFLD_02554 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
MIOPJFLD_02555 8.9e-136 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MIOPJFLD_02556 3.3e-104 yqeD S SNARE associated Golgi protein
MIOPJFLD_02557 6.1e-168 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
MIOPJFLD_02558 5.7e-132 yqeB
MIOPJFLD_02559 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
MIOPJFLD_02560 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MIOPJFLD_02561 2e-68 psiE S Protein PsiE homolog
MIOPJFLD_02562 3.8e-235 yrkQ T Histidine kinase
MIOPJFLD_02563 2.6e-126 T Transcriptional regulator
MIOPJFLD_02564 3.4e-222 yrkO P Protein of unknown function (DUF418)
MIOPJFLD_02565 8.7e-104 yrkN K Acetyltransferase (GNAT) family
MIOPJFLD_02566 5.7e-97 ywrO S Flavodoxin-like fold
MIOPJFLD_02567 1.7e-79 S Protein of unknown function with HXXEE motif
MIOPJFLD_02568 2.6e-114 yrkJ S membrane transporter protein
MIOPJFLD_02569 6e-35 yrkI O Belongs to the sulfur carrier protein TusA family
MIOPJFLD_02570 4.9e-207 yrkH P Rhodanese Homology Domain
MIOPJFLD_02571 1.7e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
MIOPJFLD_02572 2.8e-82 yrkE O DsrE/DsrF/DrsH-like family
MIOPJFLD_02573 7.8e-39 yrkD S protein conserved in bacteria
MIOPJFLD_02574 1.9e-20
MIOPJFLD_02575 3.8e-107 yrkC G Cupin domain
MIOPJFLD_02576 6.9e-150 bltR K helix_turn_helix, mercury resistance
MIOPJFLD_02577 2.5e-209 blt EGP Major facilitator Superfamily
MIOPJFLD_02578 9.1e-83 bltD 2.3.1.57 K FR47-like protein
MIOPJFLD_02579 3.7e-230 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MIOPJFLD_02580 8.7e-16 S YrzO-like protein
MIOPJFLD_02581 1.7e-168 yrdR EG EamA-like transporter family
MIOPJFLD_02582 3.9e-159 yrdQ K Transcriptional regulator
MIOPJFLD_02583 3.3e-197 trkA P Oxidoreductase
MIOPJFLD_02584 7.7e-153 czcD P COG1230 Co Zn Cd efflux system component
MIOPJFLD_02585 1.5e-16 yodA S tautomerase
MIOPJFLD_02586 2.5e-226 brnQ E Component of the transport system for branched-chain amino acids
MIOPJFLD_02587 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
MIOPJFLD_02588 2.8e-137 azlC E AzlC protein
MIOPJFLD_02589 5.3e-78 bkdR K helix_turn_helix ASNC type
MIOPJFLD_02590 2.6e-40 yrdF K ribonuclease inhibitor
MIOPJFLD_02591 7.3e-228 cypA C Cytochrome P450
MIOPJFLD_02592 5e-99 yrdC 3.5.1.19 Q Isochorismatase family
MIOPJFLD_02593 2.6e-54 S Protein of unknown function (DUF2568)
MIOPJFLD_02594 6.4e-90 yrdA S DinB family
MIOPJFLD_02595 7.2e-166 aadK G Streptomycin adenylyltransferase
MIOPJFLD_02596 3.2e-192 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MIOPJFLD_02597 1.9e-144 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MIOPJFLD_02598 8.7e-125 yrpD S Domain of unknown function, YrpD
MIOPJFLD_02599 1.5e-100 K helix_turn_helix gluconate operon transcriptional repressor
MIOPJFLD_02601 1.3e-209 rbtT P Major Facilitator Superfamily
MIOPJFLD_02602 2.4e-112 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIOPJFLD_02603 3.8e-152 2.2.1.1 G Transketolase, pyrimidine binding domain
MIOPJFLD_02604 4.4e-136 tktA 2.2.1.1 G COG3959 Transketolase, N-terminal subunit
MIOPJFLD_02606 3.2e-219 yfjF U Belongs to the major facilitator superfamily
MIOPJFLD_02607 1.8e-65 napB K MarR family transcriptional regulator
MIOPJFLD_02608 8.7e-115 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
MIOPJFLD_02609 7.7e-94 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
MIOPJFLD_02610 1.9e-186 yrpG C Aldo/keto reductase family
MIOPJFLD_02611 4e-150 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
MIOPJFLD_02612 3.8e-41 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MIOPJFLD_02613 9.9e-149 S Alpha beta hydrolase
MIOPJFLD_02614 1.9e-59 T sh3 domain protein
MIOPJFLD_02615 2.4e-61 T sh3 domain protein
MIOPJFLD_02616 1.3e-66 E Glyoxalase-like domain
MIOPJFLD_02617 5.3e-37 yraG
MIOPJFLD_02618 6.4e-63 yraF M Spore coat protein
MIOPJFLD_02619 1.1e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MIOPJFLD_02620 1.7e-25 yraE
MIOPJFLD_02621 1.1e-49 yraD M Spore coat protein
MIOPJFLD_02622 4.3e-47 yraB K helix_turn_helix, mercury resistance
MIOPJFLD_02623 4e-24 yphJ 4.1.1.44 S peroxiredoxin activity
MIOPJFLD_02624 2.8e-196 adhA 1.1.1.1 C alcohol dehydrogenase
MIOPJFLD_02625 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
MIOPJFLD_02626 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
MIOPJFLD_02627 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
MIOPJFLD_02628 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
MIOPJFLD_02629 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
MIOPJFLD_02630 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
MIOPJFLD_02631 0.0 levR K PTS system fructose IIA component
MIOPJFLD_02632 3.3e-253 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
MIOPJFLD_02633 3.6e-106 yrhP E LysE type translocator
MIOPJFLD_02634 4.1e-150 yrhO K Archaeal transcriptional regulator TrmB
MIOPJFLD_02635 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
MIOPJFLD_02636 6.1e-149 rsiV S Protein of unknown function (DUF3298)
MIOPJFLD_02637 0.0 yrhL I Acyltransferase family
MIOPJFLD_02638 1.2e-43 yrhK S YrhK-like protein
MIOPJFLD_02639 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
MIOPJFLD_02640 3.3e-101 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
MIOPJFLD_02641 7.2e-95 yrhH Q methyltransferase
MIOPJFLD_02644 1.8e-142 focA P Formate nitrite
MIOPJFLD_02645 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
MIOPJFLD_02646 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
MIOPJFLD_02647 1.4e-78 yrhD S Protein of unknown function (DUF1641)
MIOPJFLD_02648 4.6e-35 yrhC S YrhC-like protein
MIOPJFLD_02649 7.5e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MIOPJFLD_02650 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
MIOPJFLD_02651 9.4e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MIOPJFLD_02652 2.2e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
MIOPJFLD_02653 1e-25 yrzA S Protein of unknown function (DUF2536)
MIOPJFLD_02654 4.5e-57 yrrS S Protein of unknown function (DUF1510)
MIOPJFLD_02655 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
MIOPJFLD_02656 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MIOPJFLD_02657 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
MIOPJFLD_02658 2.7e-246 yegQ O COG0826 Collagenase and related proteases
MIOPJFLD_02659 4.3e-172 yegQ O Peptidase U32
MIOPJFLD_02660 1.7e-119 yrrM 2.1.1.104 S O-methyltransferase
MIOPJFLD_02661 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MIOPJFLD_02662 1.2e-45 yrzB S Belongs to the UPF0473 family
MIOPJFLD_02663 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MIOPJFLD_02664 1.7e-41 yrzL S Belongs to the UPF0297 family
MIOPJFLD_02665 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MIOPJFLD_02666 2.7e-170 yrrI S AI-2E family transporter
MIOPJFLD_02667 1.9e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MIOPJFLD_02668 4.8e-143 glnH ET Belongs to the bacterial solute-binding protein 3 family
MIOPJFLD_02669 1.8e-108 gluC P ABC transporter
MIOPJFLD_02670 7.6e-107 glnP P ABC transporter
MIOPJFLD_02671 8e-08 S Protein of unknown function (DUF3918)
MIOPJFLD_02672 9.8e-31 yrzR
MIOPJFLD_02673 1.7e-81 yrrD S protein conserved in bacteria
MIOPJFLD_02674 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MIOPJFLD_02675 1.4e-15 S COG0457 FOG TPR repeat
MIOPJFLD_02676 2.5e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MIOPJFLD_02677 2.2e-210 iscS 2.8.1.7 E Cysteine desulfurase
MIOPJFLD_02678 1.2e-70 cymR K Transcriptional regulator
MIOPJFLD_02679 1.1e-234 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MIOPJFLD_02680 9e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MIOPJFLD_02681 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MIOPJFLD_02682 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
MIOPJFLD_02684 1.1e-262 lytH 3.5.1.28 M COG3103 SH3 domain protein
MIOPJFLD_02685 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MIOPJFLD_02686 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MIOPJFLD_02687 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MIOPJFLD_02688 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MIOPJFLD_02689 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
MIOPJFLD_02690 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
MIOPJFLD_02691 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MIOPJFLD_02692 1.6e-48 yrzD S Post-transcriptional regulator
MIOPJFLD_02693 2.4e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MIOPJFLD_02694 1.7e-111 yrbG S membrane
MIOPJFLD_02695 2.2e-73 yrzE S Protein of unknown function (DUF3792)
MIOPJFLD_02696 8e-39 yajC U Preprotein translocase subunit YajC
MIOPJFLD_02697 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MIOPJFLD_02698 7.5e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MIOPJFLD_02699 2.6e-18 yrzS S Protein of unknown function (DUF2905)
MIOPJFLD_02700 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MIOPJFLD_02701 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MIOPJFLD_02702 4.8e-93 bofC S BofC C-terminal domain
MIOPJFLD_02703 4.5e-252 csbX EGP Major facilitator Superfamily
MIOPJFLD_02704 1.7e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
MIOPJFLD_02705 6.5e-119 yrzF T serine threonine protein kinase
MIOPJFLD_02707 2.3e-51 S Family of unknown function (DUF5412)
MIOPJFLD_02708 5.3e-262 alsT E Sodium alanine symporter
MIOPJFLD_02709 3.6e-126 yebC K transcriptional regulatory protein
MIOPJFLD_02710 1.3e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MIOPJFLD_02711 8.3e-157 safA M spore coat assembly protein SafA
MIOPJFLD_02712 4.1e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MIOPJFLD_02713 8.1e-157 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
MIOPJFLD_02714 7e-300 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
MIOPJFLD_02715 5.9e-227 nifS 2.8.1.7 E Cysteine desulfurase
MIOPJFLD_02716 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
MIOPJFLD_02717 7.6e-163 pheA 4.2.1.51 E Prephenate dehydratase
MIOPJFLD_02718 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
MIOPJFLD_02719 5.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MIOPJFLD_02720 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
MIOPJFLD_02721 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MIOPJFLD_02722 4.1e-56 ysxB J ribosomal protein
MIOPJFLD_02723 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
MIOPJFLD_02724 9.2e-161 spoIVFB S Stage IV sporulation protein
MIOPJFLD_02725 8.5e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
MIOPJFLD_02726 2.5e-144 minD D Belongs to the ParA family
MIOPJFLD_02727 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MIOPJFLD_02728 1.4e-84 mreD M shape-determining protein
MIOPJFLD_02729 2.8e-157 mreC M Involved in formation and maintenance of cell shape
MIOPJFLD_02730 1.8e-184 mreB D Rod shape-determining protein MreB
MIOPJFLD_02731 1.5e-124 radC E Belongs to the UPF0758 family
MIOPJFLD_02732 2.8e-102 maf D septum formation protein Maf
MIOPJFLD_02733 3.8e-166 spoIIB S Sporulation related domain
MIOPJFLD_02734 3.3e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MIOPJFLD_02735 9.6e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MIOPJFLD_02736 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MIOPJFLD_02737 1.6e-25
MIOPJFLD_02738 1.3e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MIOPJFLD_02739 1.6e-220 spoVID M stage VI sporulation protein D
MIOPJFLD_02740 1.6e-246 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
MIOPJFLD_02741 2.8e-182 hemB 4.2.1.24 H Belongs to the ALAD family
MIOPJFLD_02742 2.4e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
MIOPJFLD_02743 8.7e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MIOPJFLD_02744 3.6e-146 hemX O cytochrome C
MIOPJFLD_02745 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MIOPJFLD_02746 3.2e-89 ysxD
MIOPJFLD_02747 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
MIOPJFLD_02748 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MIOPJFLD_02749 9.2e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
MIOPJFLD_02750 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MIOPJFLD_02751 1.8e-226 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MIOPJFLD_02752 1.1e-186 ysoA H Tetratricopeptide repeat
MIOPJFLD_02753 7.6e-114 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MIOPJFLD_02754 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MIOPJFLD_02755 5.7e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MIOPJFLD_02756 9.3e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MIOPJFLD_02757 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MIOPJFLD_02758 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
MIOPJFLD_02759 0.0 ilvB 2.2.1.6 E Acetolactate synthase
MIOPJFLD_02761 9.6e-77 ysnE K acetyltransferase
MIOPJFLD_02762 2.9e-132 ysnF S protein conserved in bacteria
MIOPJFLD_02764 5.3e-92 ysnB S Phosphoesterase
MIOPJFLD_02765 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MIOPJFLD_02766 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MIOPJFLD_02767 5e-196 gerM S COG5401 Spore germination protein
MIOPJFLD_02768 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MIOPJFLD_02769 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
MIOPJFLD_02770 3.3e-30 gerE K Transcriptional regulator
MIOPJFLD_02771 6.5e-78 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
MIOPJFLD_02772 1.7e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
MIOPJFLD_02773 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
MIOPJFLD_02774 2.4e-107 sdhC C succinate dehydrogenase
MIOPJFLD_02775 1.2e-79 yslB S Protein of unknown function (DUF2507)
MIOPJFLD_02776 6.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
MIOPJFLD_02777 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MIOPJFLD_02778 2e-52 trxA O Belongs to the thioredoxin family
MIOPJFLD_02779 2.6e-304 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
MIOPJFLD_02781 1.3e-176 etfA C Electron transfer flavoprotein
MIOPJFLD_02782 1.3e-134 etfB C Electron transfer flavoprotein
MIOPJFLD_02783 2.7e-135 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
MIOPJFLD_02784 4e-99 fadR K Transcriptional regulator
MIOPJFLD_02785 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MIOPJFLD_02786 7.3e-68 yshE S membrane
MIOPJFLD_02787 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MIOPJFLD_02788 0.0 polX L COG1796 DNA polymerase IV (family X)
MIOPJFLD_02789 1.3e-85 cvpA S membrane protein, required for colicin V production
MIOPJFLD_02790 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MIOPJFLD_02791 7.1e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MIOPJFLD_02792 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MIOPJFLD_02793 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MIOPJFLD_02794 9.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MIOPJFLD_02795 5.8e-32 sspI S Belongs to the SspI family
MIOPJFLD_02796 8.6e-204 ysfB KT regulator
MIOPJFLD_02797 5.7e-261 glcD 1.1.3.15 C Glycolate oxidase subunit
MIOPJFLD_02798 2.3e-256 glcF C Glycolate oxidase
MIOPJFLD_02799 4.5e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
MIOPJFLD_02800 0.0 cstA T Carbon starvation protein
MIOPJFLD_02801 3.9e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
MIOPJFLD_02802 3.4e-144 araQ G transport system permease
MIOPJFLD_02803 4.2e-167 araP G carbohydrate transport
MIOPJFLD_02804 5.3e-253 araN G carbohydrate transport
MIOPJFLD_02805 7.5e-222 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
MIOPJFLD_02806 3e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
MIOPJFLD_02807 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MIOPJFLD_02808 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
MIOPJFLD_02809 1.6e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
MIOPJFLD_02810 3.1e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
MIOPJFLD_02811 5.8e-205 ysdC G COG1363 Cellulase M and related proteins
MIOPJFLD_02812 3.5e-67 ysdB S Sigma-w pathway protein YsdB
MIOPJFLD_02813 7.5e-45 ysdA S Membrane
MIOPJFLD_02814 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MIOPJFLD_02815 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MIOPJFLD_02816 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MIOPJFLD_02818 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MIOPJFLD_02819 3.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MIOPJFLD_02820 1.6e-129 lytT T COG3279 Response regulator of the LytR AlgR family
MIOPJFLD_02821 0.0 lytS 2.7.13.3 T Histidine kinase
MIOPJFLD_02822 2.8e-148 ysaA S HAD-hyrolase-like
MIOPJFLD_02823 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MIOPJFLD_02825 1.4e-158 ytxC S YtxC-like family
MIOPJFLD_02826 6e-109 ytxB S SNARE associated Golgi protein
MIOPJFLD_02827 6.6e-173 dnaI L Primosomal protein DnaI
MIOPJFLD_02828 7.7e-266 dnaB L Membrane attachment protein
MIOPJFLD_02829 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MIOPJFLD_02830 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MIOPJFLD_02831 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MIOPJFLD_02832 4.9e-66 ytcD K Transcriptional regulator
MIOPJFLD_02833 2.4e-204 ytbD EGP Major facilitator Superfamily
MIOPJFLD_02834 2e-160 ytbE S reductase
MIOPJFLD_02835 2.9e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MIOPJFLD_02836 1.1e-107 ytaF P Probably functions as a manganese efflux pump
MIOPJFLD_02837 3.9e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MIOPJFLD_02838 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MIOPJFLD_02839 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
MIOPJFLD_02840 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MIOPJFLD_02841 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
MIOPJFLD_02842 4.1e-242 icd 1.1.1.42 C isocitrate
MIOPJFLD_02843 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
MIOPJFLD_02844 2.3e-70 yeaL S membrane
MIOPJFLD_02845 2.6e-192 ytvI S sporulation integral membrane protein YtvI
MIOPJFLD_02846 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
MIOPJFLD_02847 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MIOPJFLD_02848 3.4e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MIOPJFLD_02849 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MIOPJFLD_02850 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MIOPJFLD_02851 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
MIOPJFLD_02852 0.0 dnaE 2.7.7.7 L DNA polymerase
MIOPJFLD_02853 3.2e-56 ytrH S Sporulation protein YtrH
MIOPJFLD_02854 8.2e-69 ytrI
MIOPJFLD_02855 9.2e-29
MIOPJFLD_02856 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
MIOPJFLD_02857 2.4e-47 ytpI S YtpI-like protein
MIOPJFLD_02858 8e-241 ytoI K transcriptional regulator containing CBS domains
MIOPJFLD_02859 5.8e-158 ytnM S membrane transporter protein
MIOPJFLD_02860 4.8e-235 ytnL 3.5.1.47 E hydrolase activity
MIOPJFLD_02861 1.5e-126 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
MIOPJFLD_02862 2.2e-254 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIOPJFLD_02863 1.2e-45 ytnI O COG0695 Glutaredoxin and related proteins
MIOPJFLD_02864 2.9e-182 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIOPJFLD_02865 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MIOPJFLD_02866 6.4e-120 tcyM U Binding-protein-dependent transport system inner membrane component
MIOPJFLD_02867 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
MIOPJFLD_02868 4.4e-149 tcyK M Bacterial periplasmic substrate-binding proteins
MIOPJFLD_02869 9.5e-152 tcyK ET Bacterial periplasmic substrate-binding proteins
MIOPJFLD_02870 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
MIOPJFLD_02871 1.5e-172 ytlI K LysR substrate binding domain
MIOPJFLD_02872 2.6e-130 ytkL S Belongs to the UPF0173 family
MIOPJFLD_02873 1.2e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIOPJFLD_02875 8.9e-267 argH 4.3.2.1 E argininosuccinate lyase
MIOPJFLD_02876 3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MIOPJFLD_02877 3.6e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
MIOPJFLD_02878 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MIOPJFLD_02879 1.2e-164 ytxK 2.1.1.72 L DNA methylase
MIOPJFLD_02880 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MIOPJFLD_02881 8.7e-70 ytfJ S Sporulation protein YtfJ
MIOPJFLD_02882 5.6e-116 ytfI S Protein of unknown function (DUF2953)
MIOPJFLD_02883 8.5e-87 yteJ S RDD family
MIOPJFLD_02884 7.4e-178 sppA OU signal peptide peptidase SppA
MIOPJFLD_02885 4.8e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MIOPJFLD_02886 0.0 ytcJ S amidohydrolase
MIOPJFLD_02887 2.9e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MIOPJFLD_02888 2e-29 sspB S spore protein
MIOPJFLD_02889 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MIOPJFLD_02890 5e-207 iscS2 2.8.1.7 E Cysteine desulfurase
MIOPJFLD_02891 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
MIOPJFLD_02892 4.6e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MIOPJFLD_02893 3.5e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
MIOPJFLD_02894 1e-108 yttP K Transcriptional regulator
MIOPJFLD_02895 2.2e-87 ytsP 1.8.4.14 T GAF domain-containing protein
MIOPJFLD_02896 2.4e-311 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
MIOPJFLD_02897 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MIOPJFLD_02899 1.8e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MIOPJFLD_02900 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MIOPJFLD_02901 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MIOPJFLD_02902 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
MIOPJFLD_02903 6.1e-224 acuC BQ histone deacetylase
MIOPJFLD_02904 6.8e-125 motS N Flagellar motor protein
MIOPJFLD_02905 6e-146 motA N flagellar motor
MIOPJFLD_02906 1.7e-182 ccpA K catabolite control protein A
MIOPJFLD_02907 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MIOPJFLD_02908 2.8e-54 ytxJ O Protein of unknown function (DUF2847)
MIOPJFLD_02909 6.6e-17 ytxH S COG4980 Gas vesicle protein
MIOPJFLD_02910 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MIOPJFLD_02911 4.8e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MIOPJFLD_02912 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
MIOPJFLD_02913 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MIOPJFLD_02914 9.8e-149 ytpQ S Belongs to the UPF0354 family
MIOPJFLD_02915 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MIOPJFLD_02916 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
MIOPJFLD_02917 4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
MIOPJFLD_02918 2.2e-51 ytzB S small secreted protein
MIOPJFLD_02919 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
MIOPJFLD_02920 7.1e-150 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
MIOPJFLD_02921 2.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MIOPJFLD_02922 7.8e-45 ytzH S YtzH-like protein
MIOPJFLD_02923 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
MIOPJFLD_02924 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
MIOPJFLD_02925 2.5e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
MIOPJFLD_02926 1.3e-165 ytlQ
MIOPJFLD_02927 8.9e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MIOPJFLD_02928 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MIOPJFLD_02929 2.3e-270 pepV 3.5.1.18 E Dipeptidase
MIOPJFLD_02930 7.2e-226 pbuO S permease
MIOPJFLD_02931 6e-200 ythQ U Bacterial ABC transporter protein EcsB
MIOPJFLD_02932 6.2e-131 ythP V ABC transporter
MIOPJFLD_02933 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
MIOPJFLD_02934 2.2e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MIOPJFLD_02935 4.7e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MIOPJFLD_02936 1.4e-231 ytfP S HI0933-like protein
MIOPJFLD_02937 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
MIOPJFLD_02938 3.1e-26 yteV S Sporulation protein Cse60
MIOPJFLD_02939 2.6e-115 yteU S Integral membrane protein
MIOPJFLD_02940 5e-256 yteT S Oxidoreductase family, C-terminal alpha/beta domain
MIOPJFLD_02941 3.9e-72 yteS G transport
MIOPJFLD_02942 1.5e-219 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
MIOPJFLD_02943 7.5e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
MIOPJFLD_02944 0.0 ytdP K Transcriptional regulator
MIOPJFLD_02945 6.9e-289 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
MIOPJFLD_02946 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
MIOPJFLD_02947 2.4e-136 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
MIOPJFLD_02948 4.5e-219 bioI 1.14.14.46 C Cytochrome P450
MIOPJFLD_02949 2.2e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MIOPJFLD_02950 1.5e-124 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MIOPJFLD_02951 2.5e-214 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MIOPJFLD_02952 2.3e-259 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
MIOPJFLD_02953 3.8e-139 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MIOPJFLD_02954 9.2e-172 ytaP S Acetyl xylan esterase (AXE1)
MIOPJFLD_02955 2.5e-189 msmR K Transcriptional regulator
MIOPJFLD_02956 6.8e-245 msmE G Bacterial extracellular solute-binding protein
MIOPJFLD_02957 6.2e-168 amyD P ABC transporter
MIOPJFLD_02958 4.4e-144 amyC P ABC transporter (permease)
MIOPJFLD_02959 4e-253 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
MIOPJFLD_02960 8.1e-51 ytwF P Sulfurtransferase
MIOPJFLD_02961 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MIOPJFLD_02962 7.7e-55 ytvB S Protein of unknown function (DUF4257)
MIOPJFLD_02963 1.1e-141 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
MIOPJFLD_02964 6e-211 yttB EGP Major facilitator Superfamily
MIOPJFLD_02965 1.1e-42 yttA 2.7.13.3 S Pfam Transposase IS66
MIOPJFLD_02966 0.0 bceB V ABC transporter (permease)
MIOPJFLD_02967 1.1e-138 bceA V ABC transporter, ATP-binding protein
MIOPJFLD_02968 3.4e-183 T PhoQ Sensor
MIOPJFLD_02969 5.7e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MIOPJFLD_02970 2.1e-233 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
MIOPJFLD_02971 9.1e-127 ytrE V ABC transporter, ATP-binding protein
MIOPJFLD_02972 6.3e-150
MIOPJFLD_02973 2e-164 P ABC-2 family transporter protein
MIOPJFLD_02974 4.2e-161 ytrB P abc transporter atp-binding protein
MIOPJFLD_02975 5.1e-66 ytrA K GntR family transcriptional regulator
MIOPJFLD_02977 6.7e-41 ytzC S Protein of unknown function (DUF2524)
MIOPJFLD_02978 8.1e-190 yhcC S Fe-S oxidoreductase
MIOPJFLD_02979 1.2e-103 ytqB J Putative rRNA methylase
MIOPJFLD_02980 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
MIOPJFLD_02981 2.8e-148 ytpA 3.1.1.5 I Alpha beta hydrolase
MIOPJFLD_02982 2.3e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MIOPJFLD_02983 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
MIOPJFLD_02984 0.0 asnB 6.3.5.4 E Asparagine synthase
MIOPJFLD_02985 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MIOPJFLD_02986 1.1e-308 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MIOPJFLD_02987 1.2e-38 ytmB S Protein of unknown function (DUF2584)
MIOPJFLD_02988 1.6e-148 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
MIOPJFLD_02989 1.8e-187 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MIOPJFLD_02990 1.4e-144 ytlC P ABC transporter
MIOPJFLD_02991 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MIOPJFLD_02992 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
MIOPJFLD_02993 7e-63 ytkC S Bacteriophage holin family
MIOPJFLD_02994 2.1e-76 dps P Belongs to the Dps family
MIOPJFLD_02996 1.1e-72 ytkA S YtkA-like
MIOPJFLD_02997 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MIOPJFLD_02998 2.8e-102 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
MIOPJFLD_02999 3.6e-41 rpmE2 J Ribosomal protein L31
MIOPJFLD_03000 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
MIOPJFLD_03001 4e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
MIOPJFLD_03002 1.1e-24 S Domain of Unknown Function (DUF1540)
MIOPJFLD_03003 4.4e-150 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
MIOPJFLD_03004 4.8e-230 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MIOPJFLD_03005 1e-136 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MIOPJFLD_03006 9.7e-169 troA P Belongs to the bacterial solute-binding protein 9 family
MIOPJFLD_03007 7.8e-213 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MIOPJFLD_03008 3.9e-273 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MIOPJFLD_03009 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MIOPJFLD_03010 1.6e-154 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MIOPJFLD_03011 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MIOPJFLD_03012 2.1e-271 menF 5.4.4.2 HQ Isochorismate synthase
MIOPJFLD_03013 2.6e-132 dksA T COG1734 DnaK suppressor protein
MIOPJFLD_03014 1.6e-151 galU 2.7.7.9 M Nucleotidyl transferase
MIOPJFLD_03015 5.4e-242 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MIOPJFLD_03016 2.6e-177 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
MIOPJFLD_03017 8.2e-232 ytcC M Glycosyltransferase Family 4
MIOPJFLD_03019 9.7e-205 cotS S Seems to be required for the assembly of the CotSA protein in spores
MIOPJFLD_03020 2.2e-215 cotSA M Glycosyl transferases group 1
MIOPJFLD_03021 4.4e-205 cotI S Spore coat protein
MIOPJFLD_03022 1.9e-75 tspO T membrane
MIOPJFLD_03023 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MIOPJFLD_03024 7.1e-283 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
MIOPJFLD_03025 8.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
MIOPJFLD_03026 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MIOPJFLD_03027 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MIOPJFLD_03036 7.8e-08
MIOPJFLD_03037 1.3e-09
MIOPJFLD_03044 2e-08
MIOPJFLD_03049 3.4e-39 S COG NOG14552 non supervised orthologous group
MIOPJFLD_03050 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
MIOPJFLD_03051 5.5e-92 M1-753 M FR47-like protein
MIOPJFLD_03052 2e-187 yuaG 3.4.21.72 S protein conserved in bacteria
MIOPJFLD_03053 2.7e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
MIOPJFLD_03054 3.9e-84 yuaE S DinB superfamily
MIOPJFLD_03055 3.9e-107 yuaD
MIOPJFLD_03056 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
MIOPJFLD_03057 1.8e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
MIOPJFLD_03058 5.5e-95 yuaC K Belongs to the GbsR family
MIOPJFLD_03059 2.2e-91 yuaB
MIOPJFLD_03060 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
MIOPJFLD_03061 2.7e-236 ktrB P Potassium
MIOPJFLD_03062 1e-38 yiaA S yiaA/B two helix domain
MIOPJFLD_03063 5.4e-152 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MIOPJFLD_03064 1e-271 yubD P Major Facilitator Superfamily
MIOPJFLD_03065 1.3e-84 cdoA 1.13.11.20 S Cysteine dioxygenase type I
MIOPJFLD_03067 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MIOPJFLD_03068 9.1e-196 yubA S transporter activity
MIOPJFLD_03069 9.7e-183 ygjR S Oxidoreductase
MIOPJFLD_03070 4e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
MIOPJFLD_03071 7.2e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
MIOPJFLD_03072 3.3e-280 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
MIOPJFLD_03073 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
MIOPJFLD_03074 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
MIOPJFLD_03075 5.1e-239 mcpA NT chemotaxis protein
MIOPJFLD_03076 1.6e-293 mcpA NT chemotaxis protein
MIOPJFLD_03077 1.5e-222 mcpA NT chemotaxis protein
MIOPJFLD_03078 3.2e-225 mcpA NT chemotaxis protein
MIOPJFLD_03079 2.6e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
MIOPJFLD_03080 2.3e-35
MIOPJFLD_03081 2.1e-72 yugU S Uncharacterised protein family UPF0047
MIOPJFLD_03082 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
MIOPJFLD_03083 1.3e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
MIOPJFLD_03084 1.4e-116 yugP S Zn-dependent protease
MIOPJFLD_03085 2.3e-38
MIOPJFLD_03086 5.4e-53 mstX S Membrane-integrating protein Mistic
MIOPJFLD_03087 2.2e-182 yugO P COG1226 Kef-type K transport systems
MIOPJFLD_03088 6.3e-72 yugN S YugN-like family
MIOPJFLD_03090 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
MIOPJFLD_03091 1.1e-228 yugK C Dehydrogenase
MIOPJFLD_03092 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
MIOPJFLD_03093 1.1e-34 yuzA S Domain of unknown function (DUF378)
MIOPJFLD_03094 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
MIOPJFLD_03095 2.1e-199 yugH 2.6.1.1 E Aminotransferase
MIOPJFLD_03096 1.6e-85 alaR K Transcriptional regulator
MIOPJFLD_03097 4.2e-155 yugF I Hydrolase
MIOPJFLD_03098 1.1e-40 yugE S Domain of unknown function (DUF1871)
MIOPJFLD_03099 7.6e-227 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MIOPJFLD_03100 1.3e-232 T PhoQ Sensor
MIOPJFLD_03101 7.4e-70 kapB G Kinase associated protein B
MIOPJFLD_03102 4.2e-115 kapD L the KinA pathway to sporulation
MIOPJFLD_03104 4.2e-184 yuxJ EGP Major facilitator Superfamily
MIOPJFLD_03105 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
MIOPJFLD_03106 9.1e-74 yuxK S protein conserved in bacteria
MIOPJFLD_03107 6.3e-78 yufK S Family of unknown function (DUF5366)
MIOPJFLD_03108 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MIOPJFLD_03109 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
MIOPJFLD_03110 4.2e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
MIOPJFLD_03111 1.9e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
MIOPJFLD_03112 2.1e-183 yufP S Belongs to the binding-protein-dependent transport system permease family
MIOPJFLD_03113 2.9e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
MIOPJFLD_03114 8.2e-233 maeN C COG3493 Na citrate symporter
MIOPJFLD_03115 5e-15
MIOPJFLD_03116 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MIOPJFLD_03117 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MIOPJFLD_03118 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MIOPJFLD_03119 4.2e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MIOPJFLD_03120 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MIOPJFLD_03121 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MIOPJFLD_03122 6.7e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
MIOPJFLD_03123 2.3e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
MIOPJFLD_03124 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MIOPJFLD_03125 3.8e-254 comP 2.7.13.3 T Histidine kinase
MIOPJFLD_03127 2.2e-128 comQ H Belongs to the FPP GGPP synthase family
MIOPJFLD_03129 8.5e-23 yuzC
MIOPJFLD_03130 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
MIOPJFLD_03131 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MIOPJFLD_03132 1.2e-102 pncA Q COG1335 Amidases related to nicotinamidase
MIOPJFLD_03133 5.1e-66 yueI S Protein of unknown function (DUF1694)
MIOPJFLD_03134 4.8e-38 yueH S YueH-like protein
MIOPJFLD_03135 1.7e-31 yueG S Spore germination protein gerPA/gerPF
MIOPJFLD_03136 3.2e-190 yueF S transporter activity
MIOPJFLD_03137 2.8e-69 S Protein of unknown function (DUF2283)
MIOPJFLD_03138 2.9e-24 S Protein of unknown function (DUF2642)
MIOPJFLD_03139 4.8e-96 yueE S phosphohydrolase
MIOPJFLD_03140 2.2e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIOPJFLD_03141 5.6e-64 yueC S Family of unknown function (DUF5383)
MIOPJFLD_03142 0.0 esaA S type VII secretion protein EsaA
MIOPJFLD_03143 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MIOPJFLD_03144 2.3e-211 essB S WXG100 protein secretion system (Wss), protein YukC
MIOPJFLD_03145 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
MIOPJFLD_03146 2.8e-45 esxA S Belongs to the WXG100 family
MIOPJFLD_03147 1.5e-228 yukF QT Transcriptional regulator
MIOPJFLD_03148 1.4e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
MIOPJFLD_03149 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
MIOPJFLD_03150 1.4e-35 mbtH S MbtH-like protein
MIOPJFLD_03151 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MIOPJFLD_03152 2.2e-176 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
MIOPJFLD_03153 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
MIOPJFLD_03154 4.3e-225 entC 5.4.4.2 HQ Isochorismate synthase
MIOPJFLD_03155 1.2e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MIOPJFLD_03156 8e-165 besA S Putative esterase
MIOPJFLD_03157 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
MIOPJFLD_03158 1.1e-93 bioY S Biotin biosynthesis protein
MIOPJFLD_03159 3.9e-211 yuiF S antiporter
MIOPJFLD_03160 1.3e-279 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MIOPJFLD_03161 1.2e-77 yuiD S protein conserved in bacteria
MIOPJFLD_03162 1.4e-116 yuiC S protein conserved in bacteria
MIOPJFLD_03163 8.4e-27 yuiB S Putative membrane protein
MIOPJFLD_03164 5.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
MIOPJFLD_03165 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
MIOPJFLD_03167 5.1e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MIOPJFLD_03168 3.8e-116 paiB K Putative FMN-binding domain
MIOPJFLD_03169 4.7e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MIOPJFLD_03170 3.7e-63 erpA S Belongs to the HesB IscA family
MIOPJFLD_03171 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MIOPJFLD_03172 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MIOPJFLD_03173 3.2e-39 yuzB S Belongs to the UPF0349 family
MIOPJFLD_03174 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
MIOPJFLD_03175 3e-56 yuzD S protein conserved in bacteria
MIOPJFLD_03176 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
MIOPJFLD_03177 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
MIOPJFLD_03178 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MIOPJFLD_03179 6.8e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MIOPJFLD_03180 7.9e-241 hom 1.1.1.3 E homoserine dehydrogenase
MIOPJFLD_03181 6.5e-198 yutH S Spore coat protein
MIOPJFLD_03182 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
MIOPJFLD_03183 4.2e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MIOPJFLD_03184 1e-75 yutE S Protein of unknown function DUF86
MIOPJFLD_03185 9.7e-48 yutD S protein conserved in bacteria
MIOPJFLD_03186 8.3e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MIOPJFLD_03187 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MIOPJFLD_03188 4.5e-196 lytH M Peptidase, M23
MIOPJFLD_03189 1e-131 yunB S Sporulation protein YunB (Spo_YunB)
MIOPJFLD_03190 1.1e-47 yunC S Domain of unknown function (DUF1805)
MIOPJFLD_03191 4.1e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
MIOPJFLD_03192 2e-141 yunE S membrane transporter protein
MIOPJFLD_03193 4.3e-171 yunF S Protein of unknown function DUF72
MIOPJFLD_03194 8.2e-60 yunG
MIOPJFLD_03195 8.6e-259 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
MIOPJFLD_03196 8.3e-301 pucR QT COG2508 Regulator of polyketide synthase expression
MIOPJFLD_03197 5.3e-232 pbuX F Permease family
MIOPJFLD_03198 2.1e-222 pbuX F xanthine
MIOPJFLD_03199 4.9e-279 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
MIOPJFLD_03200 1.7e-54 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
MIOPJFLD_03202 1.5e-94 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
MIOPJFLD_03203 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MIOPJFLD_03204 2.9e-148 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
MIOPJFLD_03205 5.3e-110 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
MIOPJFLD_03206 6.3e-182 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MIOPJFLD_03207 1.9e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
MIOPJFLD_03208 6.4e-232 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MIOPJFLD_03209 7e-169 bsn L Ribonuclease
MIOPJFLD_03210 5.9e-205 msmX P Belongs to the ABC transporter superfamily
MIOPJFLD_03211 3.3e-135 yurK K UTRA
MIOPJFLD_03212 1.1e-158 yurL 2.7.1.218 G pfkB family carbohydrate kinase
MIOPJFLD_03213 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
MIOPJFLD_03214 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
MIOPJFLD_03215 1.5e-239 yurO G COG1653 ABC-type sugar transport system, periplasmic component
MIOPJFLD_03216 2.6e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
MIOPJFLD_03217 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
MIOPJFLD_03218 3.4e-208 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
MIOPJFLD_03220 1.8e-41
MIOPJFLD_03221 2.9e-66 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MIOPJFLD_03222 7.9e-271 sufB O FeS cluster assembly
MIOPJFLD_03223 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
MIOPJFLD_03224 6.1e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MIOPJFLD_03225 1.4e-245 sufD O assembly protein SufD
MIOPJFLD_03226 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MIOPJFLD_03227 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MIOPJFLD_03228 7.2e-147 metQ P Belongs to the NlpA lipoprotein family
MIOPJFLD_03229 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
MIOPJFLD_03230 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MIOPJFLD_03231 2.4e-56 yusD S SCP-2 sterol transfer family
MIOPJFLD_03232 5.6e-55 traF CO Thioredoxin
MIOPJFLD_03233 1.6e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
MIOPJFLD_03234 1.1e-39 yusG S Protein of unknown function (DUF2553)
MIOPJFLD_03235 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MIOPJFLD_03236 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
MIOPJFLD_03237 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
MIOPJFLD_03238 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
MIOPJFLD_03239 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
MIOPJFLD_03240 8.1e-09 S YuzL-like protein
MIOPJFLD_03241 1.2e-163 fadM E Proline dehydrogenase
MIOPJFLD_03242 5.1e-40
MIOPJFLD_03243 5.4e-53 yusN M Coat F domain
MIOPJFLD_03244 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
MIOPJFLD_03245 1e-290 yusP P Major facilitator superfamily
MIOPJFLD_03246 2.7e-64 yusQ S Tautomerase enzyme
MIOPJFLD_03247 5e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MIOPJFLD_03248 2.2e-157 yusT K LysR substrate binding domain
MIOPJFLD_03249 1.1e-46 yusU S Protein of unknown function (DUF2573)
MIOPJFLD_03250 1e-153 yusV 3.6.3.34 HP ABC transporter
MIOPJFLD_03251 2.5e-66 S YusW-like protein
MIOPJFLD_03252 1.8e-299 pepF2 E COG1164 Oligoendopeptidase F
MIOPJFLD_03253 1.9e-150 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MIOPJFLD_03254 1.2e-79 dps P Ferritin-like domain
MIOPJFLD_03255 7.6e-234 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MIOPJFLD_03256 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MIOPJFLD_03257 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
MIOPJFLD_03258 4.3e-158 yuxN K Transcriptional regulator
MIOPJFLD_03259 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MIOPJFLD_03260 2.3e-24 S Protein of unknown function (DUF3970)
MIOPJFLD_03261 1.4e-246 gerAA EG Spore germination protein
MIOPJFLD_03262 1.3e-196 gerAB E Spore germination protein
MIOPJFLD_03263 1.1e-182 gerAC S Spore germination B3/ GerAC like, C-terminal
MIOPJFLD_03264 3e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MIOPJFLD_03265 1.6e-186 vraS 2.7.13.3 T Histidine kinase
MIOPJFLD_03266 1.2e-126 yvqF S Cell wall-active antibiotics response 4TMS YvqF
MIOPJFLD_03267 1.1e-118 liaG S Putative adhesin
MIOPJFLD_03268 9.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
MIOPJFLD_03269 7.3e-62 liaI S membrane
MIOPJFLD_03270 7e-226 yvqJ EGP Major facilitator Superfamily
MIOPJFLD_03271 1.3e-99 yvqK 2.5.1.17 S Adenosyltransferase
MIOPJFLD_03272 3.6e-241 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
MIOPJFLD_03273 1.9e-184 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIOPJFLD_03274 2.2e-168 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
MIOPJFLD_03275 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MIOPJFLD_03276 4.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
MIOPJFLD_03277 0.0 T PhoQ Sensor
MIOPJFLD_03278 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MIOPJFLD_03279 7.2e-23
MIOPJFLD_03280 2.1e-97 yvrI K RNA polymerase
MIOPJFLD_03281 6.9e-19 S YvrJ protein family
MIOPJFLD_03282 8.1e-229 oxdC 4.1.1.2 G Oxalate decarboxylase
MIOPJFLD_03283 1.3e-64 yvrL S Regulatory protein YrvL
MIOPJFLD_03284 5.3e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
MIOPJFLD_03285 2.3e-122 macB V ABC transporter, ATP-binding protein
MIOPJFLD_03286 1.4e-175 M Efflux transporter rnd family, mfp subunit
MIOPJFLD_03287 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
MIOPJFLD_03288 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIOPJFLD_03289 4.6e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIOPJFLD_03290 2e-177 fhuD P ABC transporter
MIOPJFLD_03292 4.9e-236 yvsH E Arginine ornithine antiporter
MIOPJFLD_03293 6.5e-16 S Small spore protein J (Spore_SspJ)
MIOPJFLD_03294 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
MIOPJFLD_03295 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MIOPJFLD_03296 2.7e-166 yvgK P COG1910 Periplasmic molybdate-binding protein domain
MIOPJFLD_03297 4.6e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
MIOPJFLD_03298 1.4e-119 modB P COG4149 ABC-type molybdate transport system, permease component
MIOPJFLD_03299 2.5e-155 yvgN S reductase
MIOPJFLD_03300 5.4e-86 yvgO
MIOPJFLD_03301 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
MIOPJFLD_03302 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
MIOPJFLD_03303 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MIOPJFLD_03304 0.0 helD 3.6.4.12 L DNA helicase
MIOPJFLD_03306 1.6e-106 yvgT S membrane
MIOPJFLD_03307 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
MIOPJFLD_03308 1.6e-104 bdbD O Thioredoxin
MIOPJFLD_03309 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
MIOPJFLD_03310 0.0 copA 3.6.3.54 P P-type ATPase
MIOPJFLD_03311 5.9e-29 copZ P Copper resistance protein CopZ
MIOPJFLD_03312 2.2e-48 csoR S transcriptional
MIOPJFLD_03313 6.9e-195 yvaA 1.1.1.371 S Oxidoreductase
MIOPJFLD_03314 7e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MIOPJFLD_03315 0.0 yvaC S Fusaric acid resistance protein-like
MIOPJFLD_03316 2.8e-72 yvaD S Family of unknown function (DUF5360)
MIOPJFLD_03317 3.4e-53 yvaE P Small Multidrug Resistance protein
MIOPJFLD_03318 3.3e-98 K Bacterial regulatory proteins, tetR family
MIOPJFLD_03319 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MIOPJFLD_03320 1.8e-15
MIOPJFLD_03323 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MIOPJFLD_03324 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MIOPJFLD_03325 5.6e-143 est 3.1.1.1 S Carboxylesterase
MIOPJFLD_03326 2.4e-23 secG U Preprotein translocase subunit SecG
MIOPJFLD_03327 7.7e-151 yvaM S Serine aminopeptidase, S33
MIOPJFLD_03328 9.8e-36 yvzC K Transcriptional
MIOPJFLD_03329 1.2e-68 K transcriptional
MIOPJFLD_03330 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
MIOPJFLD_03331 2.2e-54 yodB K transcriptional
MIOPJFLD_03332 3.2e-218 NT chemotaxis protein
MIOPJFLD_03333 1.1e-152 T His Kinase A (phosphoacceptor) domain
MIOPJFLD_03334 2.5e-105 K Transcriptional regulatory protein, C terminal
MIOPJFLD_03335 1.7e-81 mutG S ABC-2 family transporter protein
MIOPJFLD_03336 1.5e-87 spaE S ABC-2 family transporter protein
MIOPJFLD_03337 4.2e-103 mutF V ABC transporter, ATP-binding protein
MIOPJFLD_03339 1.1e-09 S Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores
MIOPJFLD_03340 9.3e-96 spaC2 V PFAM Lanthionine synthetase
MIOPJFLD_03341 1.3e-156 spaT V ABC transporter
MIOPJFLD_03342 1.3e-196 spaB S Lantibiotic dehydratase, C terminus
MIOPJFLD_03343 4.7e-104 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
MIOPJFLD_03344 8e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MIOPJFLD_03345 3.6e-109 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
MIOPJFLD_03346 1.2e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MIOPJFLD_03347 2.1e-62 yvbF K Belongs to the GbsR family
MIOPJFLD_03348 1.9e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
MIOPJFLD_03349 6.1e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MIOPJFLD_03350 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
MIOPJFLD_03351 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MIOPJFLD_03352 3.5e-97 yvbF K Belongs to the GbsR family
MIOPJFLD_03353 2.8e-90 yvbG U UPF0056 membrane protein
MIOPJFLD_03354 1.9e-112 yvbH S YvbH-like oligomerisation region
MIOPJFLD_03355 1.2e-121 exoY M Membrane
MIOPJFLD_03356 6.8e-251 tcaA S response to antibiotic
MIOPJFLD_03357 8.3e-76 yvbK 3.1.3.25 K acetyltransferase
MIOPJFLD_03358 1.9e-242 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MIOPJFLD_03359 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
MIOPJFLD_03360 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MIOPJFLD_03361 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MIOPJFLD_03362 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MIOPJFLD_03363 9.1e-184 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MIOPJFLD_03364 1.6e-252 araE EGP Major facilitator Superfamily
MIOPJFLD_03365 5.5e-203 araR K transcriptional
MIOPJFLD_03366 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIOPJFLD_03367 5.1e-159 yvbU K Transcriptional regulator
MIOPJFLD_03368 7.2e-156 yvbV EG EamA-like transporter family
MIOPJFLD_03369 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
MIOPJFLD_03370 1.1e-192 yvbX S Glycosyl hydrolase
MIOPJFLD_03371 7.5e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MIOPJFLD_03372 4.6e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
MIOPJFLD_03373 6.5e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MIOPJFLD_03374 3.8e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MIOPJFLD_03375 1.1e-193 desK 2.7.13.3 T Histidine kinase
MIOPJFLD_03376 4e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
MIOPJFLD_03377 2.4e-159 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
MIOPJFLD_03378 4.4e-157 rsbQ S Alpha/beta hydrolase family
MIOPJFLD_03379 2.4e-199 rsbU 3.1.3.3 T response regulator
MIOPJFLD_03380 9.8e-252 galA 3.2.1.89 G arabinogalactan
MIOPJFLD_03381 0.0 lacA 3.2.1.23 G beta-galactosidase
MIOPJFLD_03382 7.2e-150 ganQ P transport
MIOPJFLD_03383 1.3e-232 malC P COG1175 ABC-type sugar transport systems, permease components
MIOPJFLD_03384 2.3e-229 cycB G COG2182 Maltose-binding periplasmic proteins domains
MIOPJFLD_03385 1.4e-184 lacR K Transcriptional regulator
MIOPJFLD_03386 1e-112 yvfI K COG2186 Transcriptional regulators
MIOPJFLD_03387 4.8e-307 yvfH C L-lactate permease
MIOPJFLD_03388 9.7e-239 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MIOPJFLD_03389 1e-31 yvfG S YvfG protein
MIOPJFLD_03390 3.5e-185 yvfF GM Exopolysaccharide biosynthesis protein
MIOPJFLD_03391 2.2e-218 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
MIOPJFLD_03392 1.5e-54 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
MIOPJFLD_03393 5.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MIOPJFLD_03394 1.2e-256 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MIOPJFLD_03395 1.2e-194 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
MIOPJFLD_03396 1.6e-202 epsI GM pyruvyl transferase
MIOPJFLD_03397 8.9e-195 epsH GT2 S Glycosyltransferase like family 2
MIOPJFLD_03398 4.8e-207 epsG S EpsG family
MIOPJFLD_03399 6.4e-218 epsF GT4 M Glycosyl transferases group 1
MIOPJFLD_03400 1.2e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MIOPJFLD_03401 1.2e-219 epsD GT4 M Glycosyl transferase 4-like
MIOPJFLD_03402 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
MIOPJFLD_03403 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
MIOPJFLD_03404 1.3e-117 ywqC M biosynthesis protein
MIOPJFLD_03405 2.8e-76 slr K transcriptional
MIOPJFLD_03406 2.4e-286 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
MIOPJFLD_03408 4.6e-93 padC Q Phenolic acid decarboxylase
MIOPJFLD_03409 9.3e-72 MA20_18690 S Protein of unknown function (DUF3237)
MIOPJFLD_03410 5.8e-126 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
MIOPJFLD_03411 8.4e-262 pbpE V Beta-lactamase
MIOPJFLD_03412 3.5e-274 sacB 2.4.1.10 GH68 M levansucrase activity
MIOPJFLD_03413 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
MIOPJFLD_03414 1.8e-295 yveA E amino acid
MIOPJFLD_03415 2.6e-106 yvdT K Transcriptional regulator
MIOPJFLD_03416 5.7e-50 ykkC P Small Multidrug Resistance protein
MIOPJFLD_03417 4.1e-50 sugE P Small Multidrug Resistance protein
MIOPJFLD_03418 4.8e-93 yvdQ S Protein of unknown function (DUF3231)
MIOPJFLD_03420 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MIOPJFLD_03421 9.1e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
MIOPJFLD_03422 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
MIOPJFLD_03423 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
MIOPJFLD_03424 8.3e-157 malA S Protein of unknown function (DUF1189)
MIOPJFLD_03425 9.5e-147 malD P transport
MIOPJFLD_03426 2.2e-243 malC P COG1175 ABC-type sugar transport systems, permease components
MIOPJFLD_03427 1.4e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
MIOPJFLD_03428 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
MIOPJFLD_03429 8.8e-173 yvdE K Transcriptional regulator
MIOPJFLD_03430 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
MIOPJFLD_03431 3.4e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
MIOPJFLD_03432 2.6e-286 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
MIOPJFLD_03433 4.8e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
MIOPJFLD_03434 4.3e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MIOPJFLD_03435 0.0 yxdM V ABC transporter (permease)
MIOPJFLD_03436 5.6e-141 yvcR V ABC transporter, ATP-binding protein
MIOPJFLD_03437 7.5e-197 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
MIOPJFLD_03438 1.9e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MIOPJFLD_03439 5.1e-22
MIOPJFLD_03440 3.6e-18
MIOPJFLD_03441 1.6e-140 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
MIOPJFLD_03442 1.6e-36 crh G Phosphocarrier protein Chr
MIOPJFLD_03443 4.1e-170 whiA K May be required for sporulation
MIOPJFLD_03444 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MIOPJFLD_03445 1.7e-165 rapZ S Displays ATPase and GTPase activities
MIOPJFLD_03446 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MIOPJFLD_03447 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MIOPJFLD_03448 2.5e-91 usp CBM50 M protein conserved in bacteria
MIOPJFLD_03449 6.5e-276 S COG0457 FOG TPR repeat
MIOPJFLD_03450 0.0 msbA2 3.6.3.44 V ABC transporter
MIOPJFLD_03452 0.0
MIOPJFLD_03453 9.9e-76
MIOPJFLD_03454 8.3e-111 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
MIOPJFLD_03455 4e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MIOPJFLD_03456 3e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MIOPJFLD_03457 5.8e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MIOPJFLD_03458 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
MIOPJFLD_03459 3.8e-227 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MIOPJFLD_03460 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MIOPJFLD_03461 5e-218 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MIOPJFLD_03462 3.8e-139 yvpB NU protein conserved in bacteria
MIOPJFLD_03463 5.1e-119 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
MIOPJFLD_03464 1.6e-80 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
MIOPJFLD_03465 1.2e-117 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MIOPJFLD_03466 1.6e-163 yvoD P COG0370 Fe2 transport system protein B
MIOPJFLD_03467 1.6e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MIOPJFLD_03468 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MIOPJFLD_03469 3.5e-219 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MIOPJFLD_03470 3.2e-130 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MIOPJFLD_03471 8.9e-133 yvoA K transcriptional
MIOPJFLD_03472 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
MIOPJFLD_03473 1.8e-70 adcR K helix_turn_helix multiple antibiotic resistance protein
MIOPJFLD_03474 3.9e-173 cypX 1.14.15.13 C Cytochrome P450
MIOPJFLD_03475 1.2e-34 cypX 1.14.15.13 C Cytochrome P450
MIOPJFLD_03476 3e-136 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
MIOPJFLD_03477 2e-86 yvmB K helix_turn_helix multiple antibiotic resistance protein
MIOPJFLD_03478 2.7e-203 yvmA EGP Major facilitator Superfamily
MIOPJFLD_03479 1.2e-50 yvlD S Membrane
MIOPJFLD_03480 2.6e-26 pspB KT PspC domain
MIOPJFLD_03481 2.4e-166 yvlB S Putative adhesin
MIOPJFLD_03482 1.8e-48 yvlA
MIOPJFLD_03483 5.7e-33 yvkN
MIOPJFLD_03484 9.2e-78 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MIOPJFLD_03485 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MIOPJFLD_03486 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MIOPJFLD_03487 1.2e-30 csbA S protein conserved in bacteria
MIOPJFLD_03488 0.0 yvkC 2.7.9.2 GT Phosphotransferase
MIOPJFLD_03489 7e-101 yvkB K Transcriptional regulator
MIOPJFLD_03490 1.3e-225 yvkA EGP Major facilitator Superfamily
MIOPJFLD_03491 3.2e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MIOPJFLD_03492 5.3e-56 swrA S Swarming motility protein
MIOPJFLD_03493 2e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
MIOPJFLD_03494 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MIOPJFLD_03495 1.6e-123 ftsE D cell division ATP-binding protein FtsE
MIOPJFLD_03496 1e-54 cccB C COG2010 Cytochrome c, mono- and diheme variants
MIOPJFLD_03497 7.9e-141 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
MIOPJFLD_03498 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MIOPJFLD_03499 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MIOPJFLD_03500 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MIOPJFLD_03501 1.8e-65
MIOPJFLD_03502 1.9e-08 fliT S bacterial-type flagellum organization
MIOPJFLD_03503 2.9e-69 fliS N flagellar protein FliS
MIOPJFLD_03504 3.7e-266 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MIOPJFLD_03505 6.1e-57 flaG N flagellar protein FlaG
MIOPJFLD_03506 1.9e-156 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MIOPJFLD_03507 9.7e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MIOPJFLD_03508 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MIOPJFLD_03509 2.2e-49 yviE
MIOPJFLD_03510 7.8e-155 flgL N Belongs to the bacterial flagellin family
MIOPJFLD_03511 1.2e-264 flgK N flagellar hook-associated protein
MIOPJFLD_03512 4.1e-78 flgN NOU FlgN protein
MIOPJFLD_03513 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
MIOPJFLD_03514 7e-74 yvyF S flagellar protein
MIOPJFLD_03515 1.2e-126 comFC S Phosphoribosyl transferase domain
MIOPJFLD_03516 5.7e-46 comFB S Late competence development protein ComFB
MIOPJFLD_03517 1.1e-264 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MIOPJFLD_03518 2.1e-154 degV S protein conserved in bacteria
MIOPJFLD_03519 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MIOPJFLD_03520 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MIOPJFLD_03521 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
MIOPJFLD_03522 6e-163 yvhJ K Transcriptional regulator
MIOPJFLD_03523 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
MIOPJFLD_03524 1.4e-231 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
MIOPJFLD_03525 4.7e-145 tuaG GT2 M Glycosyltransferase like family 2
MIOPJFLD_03526 3.9e-114 tuaF M protein involved in exopolysaccharide biosynthesis
MIOPJFLD_03527 9.1e-262 tuaE M Teichuronic acid biosynthesis protein
MIOPJFLD_03528 6.9e-259 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MIOPJFLD_03529 3.4e-219 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
MIOPJFLD_03530 5.7e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MIOPJFLD_03531 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MIOPJFLD_03532 1.9e-94 M Glycosyltransferase like family 2
MIOPJFLD_03533 1.1e-206 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MIOPJFLD_03534 0.0 lytB 3.5.1.28 D Stage II sporulation protein
MIOPJFLD_03535 1e-11
MIOPJFLD_03536 1.6e-158 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MIOPJFLD_03537 2.1e-213 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MIOPJFLD_03538 2.1e-88 M Glycosyltransferase like family 2
MIOPJFLD_03539 1.9e-100 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
MIOPJFLD_03540 8.3e-23 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
MIOPJFLD_03541 2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MIOPJFLD_03542 4.9e-269 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MIOPJFLD_03543 1e-132 tagG GM Transport permease protein
MIOPJFLD_03544 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MIOPJFLD_03545 5.3e-240 ggaA M Glycosyltransferase like family 2
MIOPJFLD_03546 1.1e-135 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MIOPJFLD_03547 9.5e-57 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
MIOPJFLD_03548 7.1e-88 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MIOPJFLD_03549 6e-95 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MIOPJFLD_03550 2.6e-105 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
MIOPJFLD_03551 6.2e-148 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
MIOPJFLD_03552 3.3e-89 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MIOPJFLD_03553 2.5e-192 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MIOPJFLD_03554 8.9e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MIOPJFLD_03555 3.3e-188 pmi 5.3.1.8 G mannose-6-phosphate isomerase
MIOPJFLD_03556 3.7e-263 gerBA EG Spore germination protein
MIOPJFLD_03557 4e-193 gerBB E Spore germination protein
MIOPJFLD_03558 2.7e-205 gerAC S Spore germination protein
MIOPJFLD_03559 1.2e-247 ywtG EGP Major facilitator Superfamily
MIOPJFLD_03560 2.3e-168 ywtF K Transcriptional regulator
MIOPJFLD_03561 2.7e-160 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
MIOPJFLD_03562 3.5e-239 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MIOPJFLD_03563 3.6e-21 ywtC
MIOPJFLD_03564 6.3e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
MIOPJFLD_03565 8.6e-70 pgsC S biosynthesis protein
MIOPJFLD_03566 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
MIOPJFLD_03568 9.3e-178 rbsR K transcriptional
MIOPJFLD_03569 1.8e-159 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MIOPJFLD_03570 1.4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MIOPJFLD_03571 8.6e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MIOPJFLD_03572 1.2e-153 rbsC G Belongs to the binding-protein-dependent transport system permease family
MIOPJFLD_03573 2.4e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
MIOPJFLD_03574 8.7e-93 batE T Sh3 type 3 domain protein
MIOPJFLD_03575 8e-48 ywsA S Protein of unknown function (DUF3892)
MIOPJFLD_03576 9.7e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
MIOPJFLD_03577 6.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
MIOPJFLD_03578 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MIOPJFLD_03579 1.1e-169 alsR K LysR substrate binding domain
MIOPJFLD_03580 1.4e-218 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MIOPJFLD_03581 1.7e-122 ywrJ
MIOPJFLD_03582 9.3e-124 cotB
MIOPJFLD_03583 6.2e-207 cotH M Spore Coat
MIOPJFLD_03584 1.3e-12
MIOPJFLD_03585 6.9e-110 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MIOPJFLD_03586 2.7e-52 S Domain of unknown function (DUF4181)
MIOPJFLD_03587 3e-303 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
MIOPJFLD_03588 8e-82 ywrC K Transcriptional regulator
MIOPJFLD_03589 1.2e-103 ywrB P Chromate transporter
MIOPJFLD_03590 1.3e-88 ywrA P COG2059 Chromate transport protein ChrA
MIOPJFLD_03591 8.7e-117 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
MIOPJFLD_03592 1.7e-25
MIOPJFLD_03593 7.1e-243 ywqJ S Pre-toxin TG
MIOPJFLD_03594 1.3e-38 ywqI S Family of unknown function (DUF5344)
MIOPJFLD_03595 9.7e-23 S Domain of unknown function (DUF5082)
MIOPJFLD_03596 1.4e-152 ywqG S Domain of unknown function (DUF1963)
MIOPJFLD_03597 9.8e-247 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MIOPJFLD_03598 7.4e-138 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
MIOPJFLD_03599 4.9e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
MIOPJFLD_03600 5.9e-116 ywqC M biosynthesis protein
MIOPJFLD_03601 1.2e-17
MIOPJFLD_03602 4.6e-307 ywqB S SWIM zinc finger
MIOPJFLD_03603 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
MIOPJFLD_03604 1.8e-156 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
MIOPJFLD_03605 3.4e-138 glcR K COG1349 Transcriptional regulators of sugar metabolism
MIOPJFLD_03606 3.7e-57 ssbB L Single-stranded DNA-binding protein
MIOPJFLD_03607 1.3e-66 ywpG
MIOPJFLD_03608 1.1e-66 ywpF S YwpF-like protein
MIOPJFLD_03609 6.7e-84 srtA 3.4.22.70 M Sortase family
MIOPJFLD_03610 0.0 M1-568 M cell wall anchor domain
MIOPJFLD_03611 3.1e-174 M1-574 T Transcriptional regulatory protein, C terminal
MIOPJFLD_03612 0.0 ywpD T PhoQ Sensor
MIOPJFLD_03613 1.3e-48 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MIOPJFLD_03614 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MIOPJFLD_03615 4.4e-197 S aspartate phosphatase
MIOPJFLD_03616 2.6e-141 flhP N flagellar basal body
MIOPJFLD_03617 1.5e-125 flhO N flagellar basal body
MIOPJFLD_03618 3.5e-180 mbl D Rod shape-determining protein
MIOPJFLD_03619 3e-44 spoIIID K Stage III sporulation protein D
MIOPJFLD_03620 2.1e-70 ywoH K COG1846 Transcriptional regulators
MIOPJFLD_03621 4.4e-203 ywoG EGP Major facilitator Superfamily
MIOPJFLD_03622 1.4e-230 ywoF P Right handed beta helix region
MIOPJFLD_03623 3.4e-280 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
MIOPJFLD_03624 9.8e-242 ywoD EGP Major facilitator superfamily
MIOPJFLD_03625 4e-104 phzA Q Isochorismatase family
MIOPJFLD_03626 2.2e-76
MIOPJFLD_03627 4.3e-225 amt P Ammonium transporter
MIOPJFLD_03628 1.6e-58 nrgB K Belongs to the P(II) protein family
MIOPJFLD_03629 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
MIOPJFLD_03630 1.6e-70 ywnJ S VanZ like family
MIOPJFLD_03631 6.9e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
MIOPJFLD_03632 1.2e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
MIOPJFLD_03633 3.4e-09 ywnC S Family of unknown function (DUF5362)
MIOPJFLD_03634 2.2e-70 ywnF S Family of unknown function (DUF5392)
MIOPJFLD_03635 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MIOPJFLD_03636 2.6e-143 mta K transcriptional
MIOPJFLD_03637 2.6e-59 ywnC S Family of unknown function (DUF5362)
MIOPJFLD_03638 4e-113 ywnB S NAD(P)H-binding
MIOPJFLD_03639 1.7e-64 ywnA K Transcriptional regulator
MIOPJFLD_03640 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MIOPJFLD_03641 2.2e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
MIOPJFLD_03642 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
MIOPJFLD_03644 3.2e-10 csbD K CsbD-like
MIOPJFLD_03645 3e-84 ywmF S Peptidase M50
MIOPJFLD_03646 1.3e-103 S response regulator aspartate phosphatase
MIOPJFLD_03647 2e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MIOPJFLD_03648 7.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MIOPJFLD_03650 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
MIOPJFLD_03651 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
MIOPJFLD_03652 9.2e-176 spoIID D Stage II sporulation protein D
MIOPJFLD_03653 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MIOPJFLD_03654 8.2e-134 ywmB S TATA-box binding
MIOPJFLD_03655 1.3e-32 ywzB S membrane
MIOPJFLD_03656 4.8e-87 ywmA
MIOPJFLD_03657 9.4e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MIOPJFLD_03658 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MIOPJFLD_03659 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MIOPJFLD_03660 6.9e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MIOPJFLD_03661 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MIOPJFLD_03662 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MIOPJFLD_03663 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MIOPJFLD_03664 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
MIOPJFLD_03665 2.5e-62 atpI S ATP synthase
MIOPJFLD_03666 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MIOPJFLD_03667 1.7e-237 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MIOPJFLD_03668 7.2e-95 ywlG S Belongs to the UPF0340 family
MIOPJFLD_03669 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
MIOPJFLD_03670 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MIOPJFLD_03671 1.7e-91 mntP P Probably functions as a manganese efflux pump
MIOPJFLD_03672 1.8e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MIOPJFLD_03673 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
MIOPJFLD_03674 3e-111 spoIIR S stage II sporulation protein R
MIOPJFLD_03675 3.7e-55 ywlA S Uncharacterised protein family (UPF0715)
MIOPJFLD_03677 1.2e-155 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MIOPJFLD_03678 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MIOPJFLD_03679 6.9e-68 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MIOPJFLD_03680 1.6e-89 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
MIOPJFLD_03681 8.6e-160 ywkB S Membrane transport protein
MIOPJFLD_03682 0.0 sfcA 1.1.1.38 C malic enzyme
MIOPJFLD_03683 5.4e-104 tdk 2.7.1.21 F thymidine kinase
MIOPJFLD_03684 1.1e-32 rpmE J Binds the 23S rRNA
MIOPJFLD_03685 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MIOPJFLD_03686 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
MIOPJFLD_03687 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MIOPJFLD_03688 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MIOPJFLD_03689 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
MIOPJFLD_03690 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
MIOPJFLD_03691 2.3e-90 ywjG S Domain of unknown function (DUF2529)
MIOPJFLD_03692 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MIOPJFLD_03693 4.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MIOPJFLD_03694 1.1e-209 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
MIOPJFLD_03695 0.0 fadF C COG0247 Fe-S oxidoreductase
MIOPJFLD_03696 1.5e-222 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MIOPJFLD_03697 7.3e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
MIOPJFLD_03698 1.8e-41 ywjC
MIOPJFLD_03699 7.3e-91 ywjB H RibD C-terminal domain
MIOPJFLD_03700 0.0 ywjA V ABC transporter
MIOPJFLD_03701 1.6e-285 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MIOPJFLD_03702 3.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
MIOPJFLD_03703 1.1e-93 narJ 1.7.5.1 C nitrate reductase
MIOPJFLD_03704 1.9e-296 narH 1.7.5.1 C Nitrate reductase, beta
MIOPJFLD_03705 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MIOPJFLD_03706 7e-86 arfM T cyclic nucleotide binding
MIOPJFLD_03707 1.7e-139 ywiC S YwiC-like protein
MIOPJFLD_03708 2.6e-129 fnr K helix_turn_helix, cAMP Regulatory protein
MIOPJFLD_03709 2.3e-213 narK P COG2223 Nitrate nitrite transporter
MIOPJFLD_03710 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MIOPJFLD_03711 4.7e-73 ywiB S protein conserved in bacteria
MIOPJFLD_03712 1e-07 S Bacteriocin subtilosin A
MIOPJFLD_03713 4.9e-270 C Fe-S oxidoreductases
MIOPJFLD_03715 3.7e-131 cbiO V ABC transporter
MIOPJFLD_03716 4.7e-233 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
MIOPJFLD_03717 1.6e-216 2.7.1.26, 2.7.7.2 L Peptidase, M16
MIOPJFLD_03718 1.7e-248 L Peptidase, M16
MIOPJFLD_03720 8.6e-246 ywhL CO amine dehydrogenase activity
MIOPJFLD_03721 2.5e-189 ywhK CO amine dehydrogenase activity
MIOPJFLD_03722 4.4e-78 S aspartate phosphatase
MIOPJFLD_03724 1.2e-49 ywhH S Aminoacyl-tRNA editing domain
MIOPJFLD_03725 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
MIOPJFLD_03726 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MIOPJFLD_03727 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MIOPJFLD_03728 3.6e-49
MIOPJFLD_03729 3.4e-94 ywhD S YwhD family
MIOPJFLD_03730 5.1e-119 ywhC S Peptidase family M50
MIOPJFLD_03731 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
MIOPJFLD_03732 9.5e-71 ywhA K Transcriptional regulator
MIOPJFLD_03733 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MIOPJFLD_03735 1e-238 mmr U Major Facilitator Superfamily
MIOPJFLD_03736 5.3e-78 yffB K Transcriptional regulator
MIOPJFLD_03737 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
MIOPJFLD_03738 5.1e-256 ywfO S COG1078 HD superfamily phosphohydrolases
MIOPJFLD_03739 3.1e-36 ywzC S Belongs to the UPF0741 family
MIOPJFLD_03740 1.7e-110 rsfA_1
MIOPJFLD_03741 3.4e-158 ywfM EG EamA-like transporter family
MIOPJFLD_03742 1.5e-155 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MIOPJFLD_03743 1.1e-156 cysL K Transcriptional regulator
MIOPJFLD_03744 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
MIOPJFLD_03745 1.1e-146 ywfI C May function as heme-dependent peroxidase
MIOPJFLD_03746 1.4e-136 IQ Enoyl-(Acyl carrier protein) reductase
MIOPJFLD_03747 1.6e-232 ywfG 2.6.1.83 E Aminotransferase class I and II
MIOPJFLD_03748 7.3e-209 bacE EGP Major facilitator Superfamily
MIOPJFLD_03749 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
MIOPJFLD_03750 3.9e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIOPJFLD_03751 6.4e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
MIOPJFLD_03752 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
MIOPJFLD_03753 8.7e-205 ywfA EGP Major facilitator Superfamily
MIOPJFLD_03754 1.1e-248 lysP E amino acid
MIOPJFLD_03755 0.0 rocB E arginine degradation protein
MIOPJFLD_03756 4.6e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
MIOPJFLD_03757 1.3e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
MIOPJFLD_03758 1.2e-77
MIOPJFLD_03759 1.3e-86 spsL 5.1.3.13 M Spore Coat
MIOPJFLD_03760 4.5e-160 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MIOPJFLD_03761 5.1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MIOPJFLD_03762 3.5e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MIOPJFLD_03763 1e-187 spsG M Spore Coat
MIOPJFLD_03764 3.5e-129 spsF M Spore Coat
MIOPJFLD_03765 3.5e-213 spsE 2.5.1.56 M acid synthase
MIOPJFLD_03766 1.2e-163 spsD 2.3.1.210 K Spore Coat
MIOPJFLD_03767 3e-223 spsC E Belongs to the DegT DnrJ EryC1 family
MIOPJFLD_03768 4.3e-269 spsB M Capsule polysaccharide biosynthesis protein
MIOPJFLD_03769 2.6e-143 spsA M Spore Coat
MIOPJFLD_03770 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MIOPJFLD_03771 4.3e-59 ywdK S small membrane protein
MIOPJFLD_03772 8.3e-238 ywdJ F Xanthine uracil
MIOPJFLD_03773 1.5e-47 ywdI S Family of unknown function (DUF5327)
MIOPJFLD_03774 1.6e-260 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
MIOPJFLD_03775 3.3e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MIOPJFLD_03776 2.3e-150 ywdF GT2,GT4 S Glycosyltransferase like family 2
MIOPJFLD_03778 5.2e-113 ywdD
MIOPJFLD_03779 2.8e-57 pex K Transcriptional regulator PadR-like family
MIOPJFLD_03780 9.3e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MIOPJFLD_03781 2e-28 ywdA
MIOPJFLD_03782 1.5e-293 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
MIOPJFLD_03783 1.6e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MIOPJFLD_03784 1e-139 focA P Formate/nitrite transporter
MIOPJFLD_03785 1.6e-149 sacT K transcriptional antiterminator
MIOPJFLD_03787 0.0 vpr O Belongs to the peptidase S8 family
MIOPJFLD_03788 3.6e-185 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIOPJFLD_03789 1.4e-136 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
MIOPJFLD_03790 2.9e-202 rodA D Belongs to the SEDS family
MIOPJFLD_03791 1.7e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
MIOPJFLD_03792 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
MIOPJFLD_03793 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
MIOPJFLD_03794 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MIOPJFLD_03795 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MIOPJFLD_03796 1e-35 ywzA S membrane
MIOPJFLD_03797 7.8e-304 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MIOPJFLD_03798 2e-227 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MIOPJFLD_03799 9.5e-60 gtcA S GtrA-like protein
MIOPJFLD_03800 1.1e-121 ywcC K transcriptional regulator
MIOPJFLD_03802 9.8e-49 ywcB S Protein of unknown function, DUF485
MIOPJFLD_03803 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MIOPJFLD_03804 2.8e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
MIOPJFLD_03805 9.3e-223 ywbN P Dyp-type peroxidase family protein
MIOPJFLD_03806 9.3e-185 ycdO P periplasmic lipoprotein involved in iron transport
MIOPJFLD_03807 2.9e-252 P COG0672 High-affinity Fe2 Pb2 permease
MIOPJFLD_03808 4.1e-116 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MIOPJFLD_03809 2.8e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MIOPJFLD_03810 4.3e-153 ywbI K Transcriptional regulator
MIOPJFLD_03811 3.7e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
MIOPJFLD_03812 2.3e-111 ywbG M effector of murein hydrolase
MIOPJFLD_03813 1.3e-208 ywbF EGP Major facilitator Superfamily
MIOPJFLD_03814 5.2e-27 ywbE S Uncharacterized conserved protein (DUF2196)
MIOPJFLD_03815 3.1e-220 ywbD 2.1.1.191 J Methyltransferase
MIOPJFLD_03816 4.4e-67 ywbC 4.4.1.5 E glyoxalase
MIOPJFLD_03817 1.3e-88 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
MIOPJFLD_03818 3.1e-12 nanM N LysM domain
MIOPJFLD_03819 2.4e-83 ywbB S Protein of unknown function (DUF2711)
MIOPJFLD_03820 4.3e-22 ywbB S Protein of unknown function (DUF2711)
MIOPJFLD_03821 3.6e-241 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MIOPJFLD_03822 1.7e-271 epr 3.4.21.62 O Belongs to the peptidase S8 family
MIOPJFLD_03823 2.6e-242 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MIOPJFLD_03824 2.4e-150 sacY K transcriptional antiterminator
MIOPJFLD_03825 1.5e-166 gspA M General stress
MIOPJFLD_03826 4.8e-123 ywaF S Integral membrane protein
MIOPJFLD_03827 4e-87 ywaE K Transcriptional regulator
MIOPJFLD_03828 1.3e-229 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MIOPJFLD_03829 1.2e-250 ywaD 3.4.11.10, 3.4.11.6 S PA domain
MIOPJFLD_03830 1e-92 K Helix-turn-helix XRE-family like proteins
MIOPJFLD_03831 3.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
MIOPJFLD_03832 9.8e-129 ynfM EGP Major facilitator Superfamily
MIOPJFLD_03833 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
MIOPJFLD_03834 5.4e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
MIOPJFLD_03835 1.1e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MIOPJFLD_03836 1.2e-232 dltB M membrane protein involved in D-alanine export
MIOPJFLD_03837 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MIOPJFLD_03838 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MIOPJFLD_03839 4.7e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
MIOPJFLD_03840 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MIOPJFLD_03841 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MIOPJFLD_03842 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
MIOPJFLD_03843 8.2e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MIOPJFLD_03844 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
MIOPJFLD_03845 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
MIOPJFLD_03846 1.1e-19 yxzF
MIOPJFLD_03847 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
MIOPJFLD_03848 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
MIOPJFLD_03849 2.9e-213 yxlH EGP Major facilitator Superfamily
MIOPJFLD_03850 2.6e-138 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MIOPJFLD_03851 4.4e-166 yxlF V ABC transporter, ATP-binding protein
MIOPJFLD_03852 1e-27 yxlE S Phospholipase_D-nuclease N-terminal
MIOPJFLD_03853 2.2e-28
MIOPJFLD_03854 8.1e-46 yxlC S Family of unknown function (DUF5345)
MIOPJFLD_03855 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
MIOPJFLD_03856 1.5e-253 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
MIOPJFLD_03857 1.6e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MIOPJFLD_03858 0.0 cydD V ATP-binding protein
MIOPJFLD_03859 1.4e-309 cydD V ATP-binding
MIOPJFLD_03860 8.4e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
MIOPJFLD_03861 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
MIOPJFLD_03862 2.7e-228 cimH C COG3493 Na citrate symporter
MIOPJFLD_03863 5.1e-309 3.4.24.84 O Peptidase family M48
MIOPJFLD_03865 4.3e-155 yxkH G Polysaccharide deacetylase
MIOPJFLD_03868 1e-08 P transporter
MIOPJFLD_03869 5.9e-205 msmK P Belongs to the ABC transporter superfamily
MIOPJFLD_03870 5.4e-164 lrp QT PucR C-terminal helix-turn-helix domain
MIOPJFLD_03871 4.3e-272 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MIOPJFLD_03872 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MIOPJFLD_03873 4.1e-73 yxkC S Domain of unknown function (DUF4352)
MIOPJFLD_03874 1.3e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MIOPJFLD_03875 1.3e-95 yxkA S Phosphatidylethanolamine-binding protein
MIOPJFLD_03876 9.6e-166 yxjO K LysR substrate binding domain
MIOPJFLD_03877 2.4e-78 S Protein of unknown function (DUF1453)
MIOPJFLD_03878 4.9e-192 yxjM T Signal transduction histidine kinase
MIOPJFLD_03879 4.1e-113 K helix_turn_helix, Lux Regulon
MIOPJFLD_03880 1e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MIOPJFLD_03882 6e-85 yxjI S LURP-one-related
MIOPJFLD_03883 9.7e-219 yxjG 2.1.1.14 E Methionine synthase
MIOPJFLD_03884 3.7e-218 yxjG 2.1.1.14 E Methionine synthase
MIOPJFLD_03885 2.8e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MIOPJFLD_03886 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MIOPJFLD_03887 1.2e-129 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MIOPJFLD_03888 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
MIOPJFLD_03889 3.9e-156 rlmA 2.1.1.187 Q Methyltransferase domain
MIOPJFLD_03890 1.9e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MIOPJFLD_03891 2.2e-101 T Domain of unknown function (DUF4163)
MIOPJFLD_03892 5.7e-21 yxiS
MIOPJFLD_03893 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
MIOPJFLD_03894 6.6e-224 citH C Citrate transporter
MIOPJFLD_03895 7.3e-143 exoK GH16 M licheninase activity
MIOPJFLD_03896 8.3e-151 licT K transcriptional antiterminator
MIOPJFLD_03897 6.6e-114
MIOPJFLD_03898 1.2e-230 yxiO S COG2270 Permeases of the major facilitator superfamily
MIOPJFLD_03899 1.9e-264 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
MIOPJFLD_03900 8e-213 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
MIOPJFLD_03903 7.7e-43 yxiJ S YxiJ-like protein
MIOPJFLD_03904 4.3e-83 yxiI S Protein of unknown function (DUF2716)
MIOPJFLD_03905 1e-135
MIOPJFLD_03906 8.3e-13 yxiG
MIOPJFLD_03907 7.6e-16 yxiG
MIOPJFLD_03908 0.0 wapA M COG3209 Rhs family protein
MIOPJFLD_03909 1.6e-163 yxxF EG EamA-like transporter family
MIOPJFLD_03910 1.1e-72 yxiE T Belongs to the universal stress protein A family
MIOPJFLD_03911 4.6e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MIOPJFLD_03912 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MIOPJFLD_03913 5.5e-53
MIOPJFLD_03914 8.3e-136 S nuclease activity
MIOPJFLD_03916 7.3e-19 S Protein conserved in bacteria
MIOPJFLD_03918 3e-125 S nuclease activity
MIOPJFLD_03919 1.4e-38 yxiC S Family of unknown function (DUF5344)
MIOPJFLD_03920 2.3e-20 S Domain of unknown function (DUF5082)
MIOPJFLD_03921 2.5e-277 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
MIOPJFLD_03922 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
MIOPJFLD_03923 6.8e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
MIOPJFLD_03924 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MIOPJFLD_03925 3.7e-235 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
MIOPJFLD_03926 2.2e-179 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
MIOPJFLD_03927 2.3e-251 lysP E amino acid
MIOPJFLD_03928 3.6e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
MIOPJFLD_03929 1.7e-205 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MIOPJFLD_03930 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MIOPJFLD_03931 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MIOPJFLD_03932 4.4e-152 yxxB S Domain of Unknown Function (DUF1206)
MIOPJFLD_03933 5.4e-198 eutH E Ethanolamine utilisation protein, EutH
MIOPJFLD_03934 1.1e-250 yxeQ S MmgE/PrpD family
MIOPJFLD_03935 5.2e-212 yxeP 3.5.1.47 E hydrolase activity
MIOPJFLD_03936 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
MIOPJFLD_03937 2.7e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
MIOPJFLD_03938 3.6e-143 yxeM M Belongs to the bacterial solute-binding protein 3 family
MIOPJFLD_03939 7.3e-94 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MIOPJFLD_03940 6.3e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIOPJFLD_03941 6.1e-185 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
MIOPJFLD_03942 2.6e-149 yidA S hydrolases of the HAD superfamily
MIOPJFLD_03945 1.3e-20 yxeE
MIOPJFLD_03946 5.6e-16 yxeD
MIOPJFLD_03947 1.4e-68
MIOPJFLD_03948 5.6e-175 fhuD P ABC transporter
MIOPJFLD_03949 5.9e-58 yxeA S Protein of unknown function (DUF1093)
MIOPJFLD_03950 0.0 yxdM V ABC transporter (permease)
MIOPJFLD_03951 2.2e-137 yxdL V ABC transporter, ATP-binding protein
MIOPJFLD_03952 3.4e-180 T PhoQ Sensor
MIOPJFLD_03953 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MIOPJFLD_03954 4.6e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
MIOPJFLD_03955 5.6e-147 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
MIOPJFLD_03956 8.6e-167 iolH G Xylose isomerase-like TIM barrel
MIOPJFLD_03957 2.8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MIOPJFLD_03958 5.1e-235 iolF EGP Major facilitator Superfamily
MIOPJFLD_03959 1.8e-175 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MIOPJFLD_03960 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MIOPJFLD_03961 2.5e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MIOPJFLD_03962 3.5e-154 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MIOPJFLD_03963 3.9e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MIOPJFLD_03964 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
MIOPJFLD_03965 8.3e-176 iolS C Aldo keto reductase
MIOPJFLD_03967 8.3e-48 yxcD S Protein of unknown function (DUF2653)
MIOPJFLD_03968 2.1e-244 csbC EGP Major facilitator Superfamily
MIOPJFLD_03969 0.0 htpG O Molecular chaperone. Has ATPase activity
MIOPJFLD_03971 7.5e-149 IQ Enoyl-(Acyl carrier protein) reductase
MIOPJFLD_03974 6.1e-238 V Peptidase C39 family
MIOPJFLD_03975 9.6e-102 M HlyD family secretion protein
MIOPJFLD_03976 4e-196 yxbF K Bacterial regulatory proteins, tetR family
MIOPJFLD_03977 2.4e-245 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
MIOPJFLD_03978 9.1e-30 yxaI S membrane protein domain
MIOPJFLD_03979 2.2e-91 S PQQ-like domain
MIOPJFLD_03980 4.8e-62 S Family of unknown function (DUF5391)
MIOPJFLD_03981 1.4e-75 yxaI S membrane protein domain
MIOPJFLD_03982 1.6e-224 P Protein of unknown function (DUF418)
MIOPJFLD_03983 7.1e-197 yxaG 1.13.11.24 S AraC-like ligand binding domain
MIOPJFLD_03984 3e-99 yxaF K Transcriptional regulator
MIOPJFLD_03985 7.3e-200 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MIOPJFLD_03986 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
MIOPJFLD_03987 5.2e-50 S LrgA family
MIOPJFLD_03988 2.6e-118 yxaC M effector of murein hydrolase
MIOPJFLD_03989 1.7e-193 yxaB GM Polysaccharide pyruvyl transferase
MIOPJFLD_03990 1.8e-204 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MIOPJFLD_03991 7.3e-127 gntR K transcriptional
MIOPJFLD_03992 3.9e-303 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
MIOPJFLD_03993 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
MIOPJFLD_03994 3.8e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MIOPJFLD_03995 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
MIOPJFLD_03996 3.8e-287 ahpF O Alkyl hydroperoxide reductase
MIOPJFLD_03997 5.6e-189 wgaE S Polysaccharide pyruvyl transferase
MIOPJFLD_03998 4.1e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MIOPJFLD_03999 9e-19 bglF G phosphotransferase system
MIOPJFLD_04000 8.7e-125 yydK K Transcriptional regulator
MIOPJFLD_04001 5.6e-11
MIOPJFLD_04002 8e-118 S ABC-2 family transporter protein
MIOPJFLD_04003 1e-108 prrC P ABC transporter
MIOPJFLD_04004 3.5e-132 yydH O Peptidase M50
MIOPJFLD_04005 2.2e-184 S Radical SAM superfamily
MIOPJFLD_04006 8e-12
MIOPJFLD_04007 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
MIOPJFLD_04008 0.0 res 3.1.21.5 V Type III restriction enzyme, res subunit
MIOPJFLD_04009 5.2e-153 mod 2.1.1.72 L DNA methylase
MIOPJFLD_04010 1.1e-129 addA 3.6.4.12 L PD-(D/E)XK nuclease superfamily
MIOPJFLD_04011 0.0 3.6.4.12 L DNA helicase
MIOPJFLD_04012 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MIOPJFLD_04013 1.1e-09 S YyzF-like protein
MIOPJFLD_04014 1.2e-62
MIOPJFLD_04015 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MIOPJFLD_04017 3.3e-31 yycQ S Protein of unknown function (DUF2651)
MIOPJFLD_04018 4.6e-208 yycP
MIOPJFLD_04019 1.1e-130 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MIOPJFLD_04020 1.9e-83 yycN 2.3.1.128 K Acetyltransferase
MIOPJFLD_04021 1.5e-187 S aspartate phosphatase
MIOPJFLD_04023 4e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
MIOPJFLD_04024 9.7e-261 rocE E amino acid
MIOPJFLD_04025 2.1e-232 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
MIOPJFLD_04026 1.3e-257 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MIOPJFLD_04027 3e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MIOPJFLD_04028 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MIOPJFLD_04029 7.3e-155 yycI S protein conserved in bacteria
MIOPJFLD_04030 4.4e-258 yycH S protein conserved in bacteria
MIOPJFLD_04031 0.0 vicK 2.7.13.3 T Histidine kinase
MIOPJFLD_04032 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MIOPJFLD_04037 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MIOPJFLD_04038 4.9e-75 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MIOPJFLD_04039 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MIOPJFLD_04040 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
MIOPJFLD_04042 1.9e-15 yycC K YycC-like protein
MIOPJFLD_04043 8.4e-221 yeaN P COG2807 Cyanate permease
MIOPJFLD_04044 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MIOPJFLD_04045 2.2e-73 rplI J binds to the 23S rRNA
MIOPJFLD_04046 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MIOPJFLD_04047 2.9e-160 yybS S membrane
MIOPJFLD_04049 3.9e-84 cotF M Spore coat protein
MIOPJFLD_04050 1.4e-68 ydeP3 K Transcriptional regulator
MIOPJFLD_04051 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
MIOPJFLD_04052 1.5e-58
MIOPJFLD_04054 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
MIOPJFLD_04055 4.8e-110 K TipAS antibiotic-recognition domain
MIOPJFLD_04056 2.4e-123
MIOPJFLD_04057 6.5e-66 yybH S SnoaL-like domain
MIOPJFLD_04058 1.7e-119 yybG S Pentapeptide repeat-containing protein
MIOPJFLD_04059 3e-218 ynfM EGP Major facilitator Superfamily
MIOPJFLD_04060 3.4e-163 yybE K Transcriptional regulator
MIOPJFLD_04061 5.5e-77 yjcF S Acetyltransferase (GNAT) domain
MIOPJFLD_04062 6.6e-76 yybC
MIOPJFLD_04063 6.6e-127 S Metallo-beta-lactamase superfamily
MIOPJFLD_04064 5.6e-77 yybA 2.3.1.57 K transcriptional
MIOPJFLD_04065 7.6e-71 yjcF S Acetyltransferase (GNAT) domain
MIOPJFLD_04066 6.5e-97 yyaS S Membrane
MIOPJFLD_04067 7.6e-94 yyaR K Acetyltransferase (GNAT) domain
MIOPJFLD_04068 3.5e-66 yyaQ S YjbR
MIOPJFLD_04069 1.5e-106 yyaP 1.5.1.3 H RibD C-terminal domain
MIOPJFLD_04070 6.7e-22 yyaR K acetyltransferase
MIOPJFLD_04071 1.5e-60 yyaN K MerR HTH family regulatory protein
MIOPJFLD_04072 2.9e-157 yyaM EG EamA-like transporter family
MIOPJFLD_04073 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
MIOPJFLD_04074 3.6e-168 yyaK S CAAX protease self-immunity
MIOPJFLD_04075 2.7e-244 EGP Major facilitator superfamily
MIOPJFLD_04076 1.1e-93 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
MIOPJFLD_04077 1.7e-66 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MIOPJFLD_04078 8.1e-179 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
MIOPJFLD_04079 4e-144 xth 3.1.11.2 L exodeoxyribonuclease III
MIOPJFLD_04080 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MIOPJFLD_04081 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MIOPJFLD_04082 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
MIOPJFLD_04083 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MIOPJFLD_04084 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MIOPJFLD_04085 2.3e-33 yyzM S protein conserved in bacteria
MIOPJFLD_04086 2.3e-176 yyaD S Membrane
MIOPJFLD_04087 1.6e-111 yyaC S Sporulation protein YyaC
MIOPJFLD_04088 2.1e-149 spo0J K Belongs to the ParB family
MIOPJFLD_04089 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
MIOPJFLD_04090 1.5e-74 S Bacterial PH domain
MIOPJFLD_04091 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MIOPJFLD_04092 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MIOPJFLD_04093 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MIOPJFLD_04094 8.3e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MIOPJFLD_04095 6.5e-108 jag S single-stranded nucleic acid binding R3H
MIOPJFLD_04096 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MIOPJFLD_04097 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)