ORF_ID e_value Gene_name EC_number CAZy COGs Description
MKELAJLE_00001 1.3e-235 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MKELAJLE_00002 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MKELAJLE_00003 2.4e-33 yaaA S S4 domain
MKELAJLE_00004 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MKELAJLE_00005 1.8e-37 yaaB S Domain of unknown function (DUF370)
MKELAJLE_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MKELAJLE_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MKELAJLE_00008 3.4e-39 S COG NOG14552 non supervised orthologous group
MKELAJLE_00011 2.7e-182 yaaC S YaaC-like Protein
MKELAJLE_00012 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MKELAJLE_00013 5.2e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MKELAJLE_00014 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MKELAJLE_00015 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MKELAJLE_00016 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MKELAJLE_00017 1.3e-09
MKELAJLE_00018 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
MKELAJLE_00019 3.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
MKELAJLE_00020 5.6e-215 yaaH M Glycoside Hydrolase Family
MKELAJLE_00021 2.4e-98 yaaI Q COG1335 Amidases related to nicotinamidase
MKELAJLE_00022 1e-84 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MKELAJLE_00023 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MKELAJLE_00024 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MKELAJLE_00025 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MKELAJLE_00026 7.9e-32 yaaL S Protein of unknown function (DUF2508)
MKELAJLE_00027 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
MKELAJLE_00028 3.4e-39 S COG NOG14552 non supervised orthologous group
MKELAJLE_00031 3.4e-31 csfB S Inhibitor of sigma-G Gin
MKELAJLE_00032 4.7e-103 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
MKELAJLE_00033 4.5e-203 yaaN P Belongs to the TelA family
MKELAJLE_00034 1.1e-275 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
MKELAJLE_00035 3.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MKELAJLE_00036 2.2e-54 yaaQ S protein conserved in bacteria
MKELAJLE_00037 1.5e-71 yaaR S protein conserved in bacteria
MKELAJLE_00038 2.2e-182 holB 2.7.7.7 L DNA polymerase III
MKELAJLE_00039 2.1e-146 yaaT S stage 0 sporulation protein
MKELAJLE_00040 4.8e-31 yabA L Involved in initiation control of chromosome replication
MKELAJLE_00041 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
MKELAJLE_00042 1.5e-49 yazA L endonuclease containing a URI domain
MKELAJLE_00043 4.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MKELAJLE_00044 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
MKELAJLE_00045 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MKELAJLE_00046 1.8e-144 tatD L hydrolase, TatD
MKELAJLE_00047 4.3e-194 rpfB GH23 T protein conserved in bacteria
MKELAJLE_00048 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MKELAJLE_00049 2.4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MKELAJLE_00050 3.3e-137 yabG S peptidase
MKELAJLE_00051 7.8e-39 veg S protein conserved in bacteria
MKELAJLE_00052 8.3e-27 sspF S DNA topological change
MKELAJLE_00053 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MKELAJLE_00054 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
MKELAJLE_00055 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
MKELAJLE_00056 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MKELAJLE_00057 6.6e-230 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MKELAJLE_00058 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MKELAJLE_00059 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MKELAJLE_00060 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MKELAJLE_00061 2.4e-39 yabK S Peptide ABC transporter permease
MKELAJLE_00062 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MKELAJLE_00063 1.5e-92 spoVT K stage V sporulation protein
MKELAJLE_00064 2.4e-287 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MKELAJLE_00065 2.7e-245 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MKELAJLE_00066 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MKELAJLE_00067 1.5e-49 yabP S Sporulation protein YabP
MKELAJLE_00068 3.9e-108 yabQ S spore cortex biosynthesis protein
MKELAJLE_00069 1.1e-44 divIC D Septum formation initiator
MKELAJLE_00070 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
MKELAJLE_00073 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
MKELAJLE_00074 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
MKELAJLE_00075 6.7e-187 KLT serine threonine protein kinase
MKELAJLE_00076 3.5e-274 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MKELAJLE_00077 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MKELAJLE_00078 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MKELAJLE_00079 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MKELAJLE_00080 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MKELAJLE_00081 3.1e-153 yacD 5.2.1.8 O peptidyl-prolyl isomerase
MKELAJLE_00082 8.9e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MKELAJLE_00083 4.7e-271 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MKELAJLE_00084 1.5e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
MKELAJLE_00085 1.6e-168 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
MKELAJLE_00086 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MKELAJLE_00087 8.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MKELAJLE_00088 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MKELAJLE_00089 4.1e-30 yazB K transcriptional
MKELAJLE_00090 3.7e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MKELAJLE_00091 1.3e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MKELAJLE_00092 3.4e-39 S COG NOG14552 non supervised orthologous group
MKELAJLE_00097 2e-08
MKELAJLE_00102 3.4e-39 S COG NOG14552 non supervised orthologous group
MKELAJLE_00103 2.9e-76 ctsR K Belongs to the CtsR family
MKELAJLE_00104 4.7e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
MKELAJLE_00105 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MKELAJLE_00106 0.0 clpC O Belongs to the ClpA ClpB family
MKELAJLE_00107 9.6e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MKELAJLE_00108 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MKELAJLE_00109 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
MKELAJLE_00110 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MKELAJLE_00111 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MKELAJLE_00112 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MKELAJLE_00113 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
MKELAJLE_00114 4.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MKELAJLE_00115 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MKELAJLE_00116 1.2e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MKELAJLE_00117 1.2e-88 yacP S RNA-binding protein containing a PIN domain
MKELAJLE_00118 4.4e-115 sigH K Belongs to the sigma-70 factor family
MKELAJLE_00119 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MKELAJLE_00120 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
MKELAJLE_00121 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MKELAJLE_00122 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MKELAJLE_00123 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MKELAJLE_00124 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MKELAJLE_00125 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
MKELAJLE_00126 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MKELAJLE_00127 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MKELAJLE_00128 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
MKELAJLE_00129 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MKELAJLE_00130 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MKELAJLE_00131 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MKELAJLE_00132 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MKELAJLE_00133 9.1e-186 ybaC 3.4.11.5 S Alpha/beta hydrolase family
MKELAJLE_00134 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
MKELAJLE_00135 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MKELAJLE_00136 3e-105 rplD J Forms part of the polypeptide exit tunnel
MKELAJLE_00137 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MKELAJLE_00138 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MKELAJLE_00139 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MKELAJLE_00140 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MKELAJLE_00141 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MKELAJLE_00142 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MKELAJLE_00143 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
MKELAJLE_00144 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MKELAJLE_00145 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MKELAJLE_00146 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MKELAJLE_00147 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MKELAJLE_00148 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MKELAJLE_00149 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MKELAJLE_00150 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MKELAJLE_00151 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MKELAJLE_00152 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MKELAJLE_00153 1.9e-23 rpmD J Ribosomal protein L30
MKELAJLE_00154 1.8e-72 rplO J binds to the 23S rRNA
MKELAJLE_00155 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MKELAJLE_00156 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MKELAJLE_00157 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
MKELAJLE_00158 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MKELAJLE_00159 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MKELAJLE_00160 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MKELAJLE_00161 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MKELAJLE_00162 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MKELAJLE_00163 3.6e-58 rplQ J Ribosomal protein L17
MKELAJLE_00164 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MKELAJLE_00165 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MKELAJLE_00166 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MKELAJLE_00167 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MKELAJLE_00168 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MKELAJLE_00169 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
MKELAJLE_00170 8.2e-145 ybaJ Q Methyltransferase domain
MKELAJLE_00171 9.7e-66 ybaK S Protein of unknown function (DUF2521)
MKELAJLE_00172 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MKELAJLE_00173 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MKELAJLE_00174 1.2e-84 gerD
MKELAJLE_00175 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
MKELAJLE_00176 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
MKELAJLE_00177 3.4e-39 S COG NOG14552 non supervised orthologous group
MKELAJLE_00180 2e-08
MKELAJLE_00184 3.4e-39 S COG NOG14552 non supervised orthologous group
MKELAJLE_00185 3.4e-39 S COG NOG14552 non supervised orthologous group
MKELAJLE_00186 4.6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
MKELAJLE_00188 1.2e-161 ybaS 1.1.1.58 S Na -dependent transporter
MKELAJLE_00189 2.2e-142 ybbA S Putative esterase
MKELAJLE_00190 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKELAJLE_00191 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKELAJLE_00192 7.2e-167 feuA P Iron-uptake system-binding protein
MKELAJLE_00193 5.4e-308 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
MKELAJLE_00194 4.4e-241 ybbC 3.2.1.52 S protein conserved in bacteria
MKELAJLE_00195 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
MKELAJLE_00196 4e-256 yfeW 3.4.16.4 V Belongs to the UPF0214 family
MKELAJLE_00197 9.8e-234 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MKELAJLE_00198 1.1e-150 ybbH K transcriptional
MKELAJLE_00199 2.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MKELAJLE_00200 6.4e-87 ybbJ J acetyltransferase
MKELAJLE_00201 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
MKELAJLE_00207 8.5e-99 sigW K Belongs to the sigma-70 factor family. ECF subfamily
MKELAJLE_00208 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MKELAJLE_00209 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MKELAJLE_00210 3e-225 ybbR S protein conserved in bacteria
MKELAJLE_00211 9.3e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MKELAJLE_00212 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MKELAJLE_00213 2.1e-176 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MKELAJLE_00214 1.4e-121 adaA 3.2.2.21 K Transcriptional regulator
MKELAJLE_00215 5.1e-101 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MKELAJLE_00216 1.5e-278 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MKELAJLE_00217 0.0 ybcC S Belongs to the UPF0753 family
MKELAJLE_00218 3.7e-96 can 4.2.1.1 P carbonic anhydrase
MKELAJLE_00219 3.9e-47
MKELAJLE_00220 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
MKELAJLE_00221 5.1e-50 ybzH K Helix-turn-helix domain
MKELAJLE_00222 2e-203 ybcL EGP Major facilitator Superfamily
MKELAJLE_00224 9.1e-239 J 4Fe-4S single cluster domain
MKELAJLE_00225 1.6e-277 V CAAX protease self-immunity
MKELAJLE_00226 1.9e-135 skfE V ABC transporter
MKELAJLE_00227 4e-248 skfF S ABC transporter
MKELAJLE_00228 7.8e-91 C HEAT repeats
MKELAJLE_00229 9.6e-79 txn CO Thioredoxin-like
MKELAJLE_00230 6.2e-182 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MKELAJLE_00231 1.5e-123 T Transcriptional regulatory protein, C terminal
MKELAJLE_00232 1.8e-173 T His Kinase A (phospho-acceptor) domain
MKELAJLE_00234 1.6e-140 KLT Protein tyrosine kinase
MKELAJLE_00235 4.8e-154 ybdN
MKELAJLE_00236 1.5e-217 ybdO S Domain of unknown function (DUF4885)
MKELAJLE_00237 2.4e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
MKELAJLE_00238 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
MKELAJLE_00239 4.9e-30 ybxH S Family of unknown function (DUF5370)
MKELAJLE_00240 7.2e-152 ybxI 3.5.2.6 V beta-lactamase
MKELAJLE_00241 1.4e-247 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
MKELAJLE_00242 4.9e-41 ybyB
MKELAJLE_00243 2.3e-290 ybeC E amino acid
MKELAJLE_00244 5.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MKELAJLE_00245 7.3e-258 glpT G -transporter
MKELAJLE_00246 2.9e-35 S Protein of unknown function (DUF2651)
MKELAJLE_00247 1.6e-171 ybfA 3.4.15.5 K FR47-like protein
MKELAJLE_00248 2.2e-224 ybfB G COG0477 Permeases of the major facilitator superfamily
MKELAJLE_00250 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
MKELAJLE_00251 8.8e-162 ybfH EG EamA-like transporter family
MKELAJLE_00252 2.3e-145 msmR K AraC-like ligand binding domain
MKELAJLE_00253 1.9e-214 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MKELAJLE_00254 6.9e-178 mpr 3.4.21.19 M Belongs to the peptidase S1B family
MKELAJLE_00256 2.5e-169 S Alpha/beta hydrolase family
MKELAJLE_00257 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MKELAJLE_00258 2.7e-85 ybfM S SNARE associated Golgi protein
MKELAJLE_00259 5.6e-149 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
MKELAJLE_00260 3.2e-46 ybfN
MKELAJLE_00261 3.6e-257 S Erythromycin esterase
MKELAJLE_00262 6.7e-167 ybfP K Transcriptional regulator
MKELAJLE_00263 3.9e-192 yceA S Belongs to the UPF0176 family
MKELAJLE_00264 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MKELAJLE_00265 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MKELAJLE_00266 2.1e-137 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MKELAJLE_00267 4.9e-128 K UTRA
MKELAJLE_00269 5.4e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MKELAJLE_00270 6.7e-262 mmuP E amino acid
MKELAJLE_00271 9.3e-183 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
MKELAJLE_00272 2.3e-257 agcS E Sodium alanine symporter
MKELAJLE_00273 1.5e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
MKELAJLE_00274 1.5e-229 phoQ 2.7.13.3 T Histidine kinase
MKELAJLE_00275 9e-170 glnL T Regulator
MKELAJLE_00276 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
MKELAJLE_00277 3.7e-274 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MKELAJLE_00278 1.2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
MKELAJLE_00279 2.2e-270 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MKELAJLE_00280 1.5e-124 ycbG K FCD
MKELAJLE_00281 3.7e-298 garD 4.2.1.42, 4.2.1.7 G Altronate
MKELAJLE_00282 1.8e-178 ycbJ S Macrolide 2'-phosphotransferase
MKELAJLE_00283 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
MKELAJLE_00284 7.3e-172 eamA1 EG spore germination
MKELAJLE_00285 1.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKELAJLE_00286 2.4e-170 T PhoQ Sensor
MKELAJLE_00287 4.8e-168 ycbN V ABC transporter, ATP-binding protein
MKELAJLE_00288 2.1e-115 S ABC-2 family transporter protein
MKELAJLE_00289 8.2e-53 ycbP S Protein of unknown function (DUF2512)
MKELAJLE_00290 1.3e-78 sleB 3.5.1.28 M Cell wall
MKELAJLE_00291 6.6e-136 ycbR T vWA found in TerF C terminus
MKELAJLE_00292 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
MKELAJLE_00293 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MKELAJLE_00294 1.2e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MKELAJLE_00295 1.4e-121 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MKELAJLE_00296 6.2e-210 ycbU E Selenocysteine lyase
MKELAJLE_00297 5.8e-229 lmrB EGP the major facilitator superfamily
MKELAJLE_00298 4.8e-102 yxaF K Transcriptional regulator
MKELAJLE_00299 2.2e-202 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MKELAJLE_00300 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
MKELAJLE_00301 2e-59 S RDD family
MKELAJLE_00302 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
MKELAJLE_00303 2e-161 2.7.13.3 T GHKL domain
MKELAJLE_00304 1.2e-126 lytR_2 T LytTr DNA-binding domain
MKELAJLE_00305 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
MKELAJLE_00306 4.5e-203 natB CP ABC-2 family transporter protein
MKELAJLE_00307 1.6e-174 yccK C Aldo keto reductase
MKELAJLE_00308 6.6e-177 ycdA S Domain of unknown function (DUF5105)
MKELAJLE_00309 5.9e-282 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
MKELAJLE_00310 6.7e-268 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
MKELAJLE_00311 1.7e-95 cwlK M D-alanyl-D-alanine carboxypeptidase
MKELAJLE_00312 5.5e-174 S response regulator aspartate phosphatase
MKELAJLE_00313 1.6e-140 IQ Enoyl-(Acyl carrier protein) reductase
MKELAJLE_00314 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
MKELAJLE_00315 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
MKELAJLE_00316 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MKELAJLE_00317 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MKELAJLE_00318 5.4e-189 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKELAJLE_00319 7.3e-56 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
MKELAJLE_00320 8.7e-40 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
MKELAJLE_00321 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
MKELAJLE_00322 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
MKELAJLE_00323 6.3e-137 terC P Protein of unknown function (DUF475)
MKELAJLE_00324 0.0 yceG S Putative component of 'biosynthetic module'
MKELAJLE_00325 2e-192 yceH P Belongs to the TelA family
MKELAJLE_00326 1e-218 naiP P Uncharacterised MFS-type transporter YbfB
MKELAJLE_00327 1.9e-209 yceJ EGP Uncharacterised MFS-type transporter YbfB
MKELAJLE_00328 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
MKELAJLE_00329 5.1e-229 proV 3.6.3.32 E glycine betaine
MKELAJLE_00330 1.3e-127 opuAB P glycine betaine
MKELAJLE_00331 5.3e-164 opuAC E glycine betaine
MKELAJLE_00332 1.2e-219 amhX S amidohydrolase
MKELAJLE_00333 1e-257 ycgA S Membrane
MKELAJLE_00334 1.1e-98 ycgB
MKELAJLE_00335 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
MKELAJLE_00336 3.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MKELAJLE_00337 6.5e-293 lctP C L-lactate permease
MKELAJLE_00338 6.2e-269 mdr EGP Major facilitator Superfamily
MKELAJLE_00339 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
MKELAJLE_00340 6.8e-113 ycgF E Lysine exporter protein LysE YggA
MKELAJLE_00341 1.2e-151 yqcI S YqcI/YcgG family
MKELAJLE_00342 5.6e-250 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
MKELAJLE_00343 2.4e-112 ycgI S Domain of unknown function (DUF1989)
MKELAJLE_00344 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MKELAJLE_00345 2.5e-109 tmrB S AAA domain
MKELAJLE_00346 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MKELAJLE_00347 3.6e-145 yafE Q ubiE/COQ5 methyltransferase family
MKELAJLE_00348 2.2e-179 oxyR3 K LysR substrate binding domain
MKELAJLE_00349 2.9e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
MKELAJLE_00350 2.9e-145 ycgL S Predicted nucleotidyltransferase
MKELAJLE_00351 5.1e-170 ycgM E Proline dehydrogenase
MKELAJLE_00352 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
MKELAJLE_00353 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MKELAJLE_00354 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
MKELAJLE_00355 2.6e-147 ycgQ S membrane
MKELAJLE_00356 1.2e-139 ycgR S permeases
MKELAJLE_00357 5.7e-163 I alpha/beta hydrolase fold
MKELAJLE_00358 1.3e-193 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
MKELAJLE_00359 9.3e-283 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
MKELAJLE_00360 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
MKELAJLE_00361 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MKELAJLE_00362 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MKELAJLE_00363 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
MKELAJLE_00364 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
MKELAJLE_00365 1.4e-172 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
MKELAJLE_00366 5.5e-109 yciB M ErfK YbiS YcfS YnhG
MKELAJLE_00367 1.4e-228 yciC S GTPases (G3E family)
MKELAJLE_00368 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
MKELAJLE_00369 1.1e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
MKELAJLE_00372 3.3e-77 yckC S membrane
MKELAJLE_00373 3.5e-52 yckD S Protein of unknown function (DUF2680)
MKELAJLE_00374 1.2e-298 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MKELAJLE_00375 3.4e-70 nin S Competence protein J (ComJ)
MKELAJLE_00376 3.2e-72 nucA M Deoxyribonuclease NucA/NucB
MKELAJLE_00377 3e-187 tlpC 2.7.13.3 NT chemotaxis protein
MKELAJLE_00378 4.6e-97 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
MKELAJLE_00379 3.3e-107 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
MKELAJLE_00380 1.3e-63 hxlR K transcriptional
MKELAJLE_00381 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKELAJLE_00382 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKELAJLE_00383 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
MKELAJLE_00384 5.7e-140 srfAD Q thioesterase
MKELAJLE_00385 4.2e-228 EGP Major Facilitator Superfamily
MKELAJLE_00386 4.9e-91 S YcxB-like protein
MKELAJLE_00387 7.4e-164 ycxC EG EamA-like transporter family
MKELAJLE_00388 4.4e-255 ycxD K GntR family transcriptional regulator
MKELAJLE_00389 5.5e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
MKELAJLE_00390 4.4e-115 yczE S membrane
MKELAJLE_00391 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MKELAJLE_00392 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
MKELAJLE_00393 1.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
MKELAJLE_00394 4.9e-162 bsdA K LysR substrate binding domain
MKELAJLE_00395 2e-109 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MKELAJLE_00396 1.8e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
MKELAJLE_00397 4e-39 bsdD 4.1.1.61 S response to toxic substance
MKELAJLE_00398 1.1e-83 yclD
MKELAJLE_00399 6.2e-162 yclE 3.4.11.5 S Alpha beta hydrolase
MKELAJLE_00400 1.5e-267 dtpT E amino acid peptide transporter
MKELAJLE_00401 2.9e-310 yclG M Pectate lyase superfamily protein
MKELAJLE_00403 6.8e-282 gerKA EG Spore germination protein
MKELAJLE_00404 1.3e-232 gerKC S spore germination
MKELAJLE_00405 9.9e-200 gerKB F Spore germination protein
MKELAJLE_00406 3.9e-122 yclH P ABC transporter
MKELAJLE_00407 1.7e-204 yclI V ABC transporter (permease) YclI
MKELAJLE_00408 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKELAJLE_00409 1.8e-262 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MKELAJLE_00410 5.2e-71 S aspartate phosphatase
MKELAJLE_00413 7.5e-242 lysC 2.7.2.4 E Belongs to the aspartokinase family
MKELAJLE_00414 1.6e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKELAJLE_00415 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKELAJLE_00416 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
MKELAJLE_00417 5.5e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
MKELAJLE_00418 1.4e-251 ycnB EGP Major facilitator Superfamily
MKELAJLE_00419 6.5e-154 ycnC K Transcriptional regulator
MKELAJLE_00420 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
MKELAJLE_00421 1.6e-45 ycnE S Monooxygenase
MKELAJLE_00422 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
MKELAJLE_00423 1.3e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MKELAJLE_00424 4.4e-247 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MKELAJLE_00425 3.4e-266 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MKELAJLE_00426 6.1e-149 glcU U Glucose uptake
MKELAJLE_00427 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKELAJLE_00428 1.3e-100 ycnI S protein conserved in bacteria
MKELAJLE_00429 1.4e-308 ycnJ P protein, homolog of Cu resistance protein CopC
MKELAJLE_00430 1.7e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
MKELAJLE_00431 7.3e-56
MKELAJLE_00432 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
MKELAJLE_00433 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
MKELAJLE_00434 7.3e-211 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
MKELAJLE_00435 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
MKELAJLE_00436 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MKELAJLE_00437 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MKELAJLE_00438 5e-113 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
MKELAJLE_00439 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
MKELAJLE_00441 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
MKELAJLE_00442 1.2e-140 ycsF S Belongs to the UPF0271 (lamB) family
MKELAJLE_00443 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
MKELAJLE_00444 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
MKELAJLE_00445 1.9e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
MKELAJLE_00446 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
MKELAJLE_00447 1.2e-132 kipR K Transcriptional regulator
MKELAJLE_00448 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
MKELAJLE_00450 1.4e-49 yczJ S biosynthesis
MKELAJLE_00451 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
MKELAJLE_00452 2.8e-176 ydhF S Oxidoreductase
MKELAJLE_00453 0.0 mtlR K transcriptional regulator, MtlR
MKELAJLE_00454 1.4e-294 ydaB IQ acyl-CoA ligase
MKELAJLE_00455 1.1e-99 ydaC Q Methyltransferase domain
MKELAJLE_00456 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKELAJLE_00457 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
MKELAJLE_00458 5e-104 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MKELAJLE_00459 6.8e-77 ydaG 1.4.3.5 S general stress protein
MKELAJLE_00460 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
MKELAJLE_00461 5.1e-47 ydzA EGP Major facilitator Superfamily
MKELAJLE_00462 2.5e-74 lrpC K Transcriptional regulator
MKELAJLE_00463 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MKELAJLE_00464 1.9e-208 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
MKELAJLE_00465 2e-152 ydaK T Diguanylate cyclase, GGDEF domain
MKELAJLE_00466 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
MKELAJLE_00467 4.5e-233 ydaM M Glycosyl transferase family group 2
MKELAJLE_00468 0.0 ydaN S Bacterial cellulose synthase subunit
MKELAJLE_00469 0.0 ydaO E amino acid
MKELAJLE_00470 4.6e-79 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
MKELAJLE_00471 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MKELAJLE_00472 9.4e-40
MKELAJLE_00473 1e-224 mntH P H( )-stimulated, divalent metal cation uptake system
MKELAJLE_00475 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
MKELAJLE_00476 3.8e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
MKELAJLE_00478 8.9e-59 ydbB G Cupin domain
MKELAJLE_00479 2.8e-63 ydbC S Domain of unknown function (DUF4937
MKELAJLE_00480 3.2e-155 ydbD P Catalase
MKELAJLE_00481 2.7e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MKELAJLE_00482 2.5e-297 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MKELAJLE_00483 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
MKELAJLE_00484 6.3e-227 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MKELAJLE_00485 4.4e-181 ydbI S AI-2E family transporter
MKELAJLE_00486 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
MKELAJLE_00487 5.5e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MKELAJLE_00488 2.7e-52 ydbL
MKELAJLE_00489 3e-220 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
MKELAJLE_00490 1.1e-18 S Fur-regulated basic protein B
MKELAJLE_00491 2.2e-07 S Fur-regulated basic protein A
MKELAJLE_00492 1.9e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MKELAJLE_00493 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MKELAJLE_00494 4.6e-202 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MKELAJLE_00495 1.9e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MKELAJLE_00496 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MKELAJLE_00497 2.1e-82 ydbS S Bacterial PH domain
MKELAJLE_00498 2.2e-263 ydbT S Membrane
MKELAJLE_00499 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
MKELAJLE_00500 2.5e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MKELAJLE_00501 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
MKELAJLE_00502 2.3e-223 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MKELAJLE_00503 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MKELAJLE_00504 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
MKELAJLE_00505 1.3e-143 rsbR T Positive regulator of sigma-B
MKELAJLE_00506 5.2e-57 rsbS T antagonist
MKELAJLE_00507 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MKELAJLE_00508 7.1e-189 rsbU 3.1.3.3 KT phosphatase
MKELAJLE_00509 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
MKELAJLE_00510 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
MKELAJLE_00511 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKELAJLE_00512 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
MKELAJLE_00516 1.5e-82 ydcG S EVE domain
MKELAJLE_00517 1.6e-76 ydcH K helix_turn_helix multiple antibiotic resistance protein
MKELAJLE_00518 0.0 yhgF K COG2183 Transcriptional accessory protein
MKELAJLE_00519 1.6e-84 ydcK S Belongs to the SprT family
MKELAJLE_00527 1.9e-211 L Belongs to the 'phage' integrase family
MKELAJLE_00528 1.3e-90 immA E IrrE N-terminal-like domain
MKELAJLE_00529 4.3e-62 yvaO K Transcriptional
MKELAJLE_00530 1.1e-16
MKELAJLE_00531 8.3e-41
MKELAJLE_00533 5.1e-63 S Bacterial protein of unknown function (DUF961)
MKELAJLE_00534 1e-273 ydcQ D Ftsk spoiiie family protein
MKELAJLE_00535 1.5e-205 nicK L Replication initiation factor
MKELAJLE_00538 1.2e-32 yddA
MKELAJLE_00539 1.5e-173 yddB S Conjugative transposon protein TcpC
MKELAJLE_00540 3e-40 yddC
MKELAJLE_00541 2.4e-95 yddD S TcpE family
MKELAJLE_00542 0.0 yddE S AAA-like domain
MKELAJLE_00543 2e-55 S Domain of unknown function (DUF1874)
MKELAJLE_00544 0.0 yddG S maturation of SSU-rRNA
MKELAJLE_00545 2.4e-189 yddH CBM50 M Lysozyme-like
MKELAJLE_00546 8.7e-87 yddI
MKELAJLE_00547 4.1e-65 S Domain of unknown function with cystatin-like fold (DUF4467)
MKELAJLE_00548 9.5e-128 S TIR domain
MKELAJLE_00549 1.4e-74 S response regulator aspartate phosphatase
MKELAJLE_00551 3.4e-161
MKELAJLE_00552 2.7e-188 luxA C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKELAJLE_00553 2.4e-71 lrpA K transcriptional
MKELAJLE_00554 3.9e-78 lrpB K transcriptional
MKELAJLE_00555 9.6e-100 yddQ 3.5.1.19 Q Isochorismatase family
MKELAJLE_00556 1.5e-143 yddR S Zn-dependent hydrolases of the beta-lactamase fold
MKELAJLE_00557 5e-227 ydeG EGP Major facilitator Superfamily
MKELAJLE_00562 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
MKELAJLE_00563 8.7e-30 cspL K Cold shock
MKELAJLE_00564 6.1e-79 carD K Transcription factor
MKELAJLE_00565 4.6e-35 ydzE EG spore germination
MKELAJLE_00566 1.1e-166 rhaS5 K AraC-like ligand binding domain
MKELAJLE_00567 2.3e-173 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MKELAJLE_00568 2.5e-166 ydeE K AraC family transcriptional regulator
MKELAJLE_00569 2.2e-265 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MKELAJLE_00570 3.4e-220 ydeG EGP Major facilitator superfamily
MKELAJLE_00571 2.9e-47 ydeH
MKELAJLE_00572 8.9e-107 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
MKELAJLE_00573 4e-116
MKELAJLE_00574 1.8e-153 ydeK EG -transporter
MKELAJLE_00575 1.5e-274 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MKELAJLE_00576 4.2e-74 maoC I N-terminal half of MaoC dehydratase
MKELAJLE_00577 8.6e-107 ydeN S Serine hydrolase
MKELAJLE_00578 1.1e-58 K HxlR-like helix-turn-helix
MKELAJLE_00579 1.9e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
MKELAJLE_00580 4.8e-69 ydeP K Transcriptional regulator
MKELAJLE_00581 1.6e-108 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
MKELAJLE_00582 1.2e-195 ydeR EGP Major facilitator Superfamily
MKELAJLE_00583 8.4e-105 ydeS K Transcriptional regulator
MKELAJLE_00584 1.3e-57 arsR K transcriptional
MKELAJLE_00585 5.2e-232 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MKELAJLE_00586 7.2e-149 ydfB J GNAT acetyltransferase
MKELAJLE_00587 1e-162 ydfC EG EamA-like transporter family
MKELAJLE_00588 1.9e-275 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MKELAJLE_00589 5.9e-117 ydfE S Flavin reductase like domain
MKELAJLE_00590 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
MKELAJLE_00591 1.5e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MKELAJLE_00593 5.3e-180 ydfH 2.7.13.3 T Histidine kinase
MKELAJLE_00594 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKELAJLE_00595 0.0 ydfJ S drug exporters of the RND superfamily
MKELAJLE_00596 1.9e-177 S Alpha/beta hydrolase family
MKELAJLE_00597 5.9e-118 S Protein of unknown function (DUF554)
MKELAJLE_00598 3.2e-147 K Bacterial transcription activator, effector binding domain
MKELAJLE_00599 1.6e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MKELAJLE_00600 9.6e-112 ydfN C nitroreductase
MKELAJLE_00601 3.6e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
MKELAJLE_00602 8.8e-63 mhqP S DoxX
MKELAJLE_00603 1.3e-57 traF CO Thioredoxin
MKELAJLE_00604 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
MKELAJLE_00605 6.3e-29
MKELAJLE_00607 4.4e-118 ydfR S Protein of unknown function (DUF421)
MKELAJLE_00608 5.2e-122 ydfS S Protein of unknown function (DUF421)
MKELAJLE_00609 1.7e-75 cotP O Belongs to the small heat shock protein (HSP20) family
MKELAJLE_00610 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
MKELAJLE_00611 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
MKELAJLE_00612 1.5e-101 K Bacterial regulatory proteins, tetR family
MKELAJLE_00613 1.9e-53 S DoxX-like family
MKELAJLE_00614 2.4e-86 yycN 2.3.1.128 K Acetyltransferase
MKELAJLE_00615 4.2e-308 expZ S ABC transporter
MKELAJLE_00616 4e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
MKELAJLE_00617 4.6e-91 dinB S DinB family
MKELAJLE_00618 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
MKELAJLE_00619 0.0 ydgH S drug exporters of the RND superfamily
MKELAJLE_00620 1e-113 drgA C nitroreductase
MKELAJLE_00621 1.1e-69 ydgJ K Winged helix DNA-binding domain
MKELAJLE_00622 2.5e-209 tcaB EGP Major facilitator Superfamily
MKELAJLE_00623 1.2e-121 ydhB S membrane transporter protein
MKELAJLE_00624 6.5e-122 ydhC K FCD
MKELAJLE_00625 3.3e-244 ydhD M Glycosyl hydrolase
MKELAJLE_00626 7e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MKELAJLE_00627 1.9e-127
MKELAJLE_00628 1.4e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
MKELAJLE_00629 4.6e-69 frataxin S Domain of unknown function (DU1801)
MKELAJLE_00631 4.1e-86 K Acetyltransferase (GNAT) domain
MKELAJLE_00632 1.8e-184 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
MKELAJLE_00633 1.7e-99 ydhK M Protein of unknown function (DUF1541)
MKELAJLE_00634 4.6e-200 pbuE EGP Major facilitator Superfamily
MKELAJLE_00635 1.1e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
MKELAJLE_00636 3.5e-52 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
MKELAJLE_00637 2e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKELAJLE_00638 2.4e-288 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MKELAJLE_00639 3.9e-133 ydhQ K UTRA
MKELAJLE_00640 9.2e-172 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
MKELAJLE_00641 4.2e-191 manA 5.3.1.8 G mannose-6-phosphate isomerase
MKELAJLE_00642 7.3e-216 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
MKELAJLE_00643 8.7e-78 ydhU P Catalase
MKELAJLE_00644 1.1e-16 ydhU P Manganese containing catalase
MKELAJLE_00647 3.4e-39 S COG NOG14552 non supervised orthologous group
MKELAJLE_00648 7.8e-08
MKELAJLE_00650 4.6e-185 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MKELAJLE_00651 9.1e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
MKELAJLE_00652 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
MKELAJLE_00653 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MKELAJLE_00654 3.6e-188 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MKELAJLE_00655 0.0 ydiF S ABC transporter
MKELAJLE_00656 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MKELAJLE_00657 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MKELAJLE_00658 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MKELAJLE_00659 8.4e-126 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MKELAJLE_00660 2.9e-27 ydiK S Domain of unknown function (DUF4305)
MKELAJLE_00661 7.9e-129 ydiL S CAAX protease self-immunity
MKELAJLE_00662 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MKELAJLE_00663 1.2e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MKELAJLE_00665 6.4e-66 KL Phage plasmid primase P4 family
MKELAJLE_00666 1.1e-250 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
MKELAJLE_00667 1.6e-232 ydiP 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
MKELAJLE_00669 1.2e-199 V AAA domain (dynein-related subfamily)
MKELAJLE_00670 4.9e-257 J LlaJI restriction endonuclease
MKELAJLE_00671 1.1e-08 ydjC S Abhydrolase domain containing 18
MKELAJLE_00672 0.0 K NB-ARC domain
MKELAJLE_00673 3.8e-201 gutB 1.1.1.14 E Dehydrogenase
MKELAJLE_00674 7.1e-256 gutA G MFS/sugar transport protein
MKELAJLE_00675 1.5e-175 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
MKELAJLE_00676 5.1e-114 pspA KT Phage shock protein A
MKELAJLE_00677 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MKELAJLE_00678 1.6e-137 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
MKELAJLE_00679 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
MKELAJLE_00680 4.7e-196 S Ion transport 2 domain protein
MKELAJLE_00681 2.7e-258 iolT EGP Major facilitator Superfamily
MKELAJLE_00682 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
MKELAJLE_00683 4.5e-64 ydjM M Lytic transglycolase
MKELAJLE_00684 4.4e-157 ydjN U Involved in the tonB-independent uptake of proteins
MKELAJLE_00686 1.4e-34 ydjO S Cold-inducible protein YdjO
MKELAJLE_00687 9.5e-160 ydjP I Alpha/beta hydrolase family
MKELAJLE_00688 2.4e-181 yeaA S Protein of unknown function (DUF4003)
MKELAJLE_00689 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
MKELAJLE_00690 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
MKELAJLE_00691 7.6e-155 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MKELAJLE_00692 1.6e-177 yeaC S COG0714 MoxR-like ATPases
MKELAJLE_00693 9.5e-225 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
MKELAJLE_00694 0.0 yebA E COG1305 Transglutaminase-like enzymes
MKELAJLE_00695 3.7e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MKELAJLE_00696 6e-212 pbuG S permease
MKELAJLE_00697 1.1e-118 yebC M Membrane
MKELAJLE_00699 4e-93 yebE S UPF0316 protein
MKELAJLE_00700 8e-28 yebG S NETI protein
MKELAJLE_00701 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MKELAJLE_00702 7e-217 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MKELAJLE_00703 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MKELAJLE_00704 1.2e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MKELAJLE_00705 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MKELAJLE_00706 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MKELAJLE_00707 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MKELAJLE_00708 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MKELAJLE_00709 7.6e-178 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MKELAJLE_00710 1.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MKELAJLE_00711 1.2e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MKELAJLE_00712 1.7e-235 purD 6.3.4.13 F Belongs to the GARS family
MKELAJLE_00713 3.5e-73 K helix_turn_helix ASNC type
MKELAJLE_00714 2.3e-232 yjeH E Amino acid permease
MKELAJLE_00715 2.7e-27 S Protein of unknown function (DUF2892)
MKELAJLE_00716 0.0 yerA 3.5.4.2 F adenine deaminase
MKELAJLE_00717 3e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
MKELAJLE_00718 4.8e-51 yerC S protein conserved in bacteria
MKELAJLE_00719 3.2e-305 yerD 1.4.7.1 E Belongs to the glutamate synthase family
MKELAJLE_00721 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MKELAJLE_00722 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MKELAJLE_00723 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MKELAJLE_00724 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
MKELAJLE_00725 1.1e-197 yerI S homoserine kinase type II (protein kinase fold)
MKELAJLE_00726 1.6e-123 sapB S MgtC SapB transporter
MKELAJLE_00727 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MKELAJLE_00728 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MKELAJLE_00729 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MKELAJLE_00730 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MKELAJLE_00731 4e-156 yerO K Transcriptional regulator
MKELAJLE_00732 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MKELAJLE_00733 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MKELAJLE_00734 1.2e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MKELAJLE_00735 3.2e-98 L Recombinase
MKELAJLE_00736 3.2e-53 L Resolvase, N terminal domain
MKELAJLE_00737 0.0 yeeA V Type II restriction enzyme, methylase subunits
MKELAJLE_00738 0.0 yeeB L DEAD-like helicases superfamily
MKELAJLE_00739 1.8e-212 pstS P T5orf172
MKELAJLE_00741 6.2e-31 S Colicin immunity protein / pyocin immunity protein
MKELAJLE_00742 5.5e-83 S Protein of unknown function, DUF600
MKELAJLE_00743 0.0 L nucleic acid phosphodiester bond hydrolysis
MKELAJLE_00744 1.8e-192 3.4.24.40 CO amine dehydrogenase activity
MKELAJLE_00745 5.5e-214 S Tetratricopeptide repeat
MKELAJLE_00747 9.4e-127 yeeN K transcriptional regulatory protein
MKELAJLE_00749 1.2e-103 dhaR3 K Transcriptional regulator
MKELAJLE_00750 9.7e-82 yesE S SnoaL-like domain
MKELAJLE_00751 2.2e-159 yesF GM NAD(P)H-binding
MKELAJLE_00752 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
MKELAJLE_00753 1.5e-45 cotJB S CotJB protein
MKELAJLE_00754 5.2e-104 cotJC P Spore Coat
MKELAJLE_00755 4.2e-103 yesJ K Acetyltransferase (GNAT) family
MKELAJLE_00757 4.4e-104 yesL S Protein of unknown function, DUF624
MKELAJLE_00758 0.0 yesM 2.7.13.3 T Histidine kinase
MKELAJLE_00759 2.9e-204 yesN K helix_turn_helix, arabinose operon control protein
MKELAJLE_00760 5e-248 yesO G Bacterial extracellular solute-binding protein
MKELAJLE_00761 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
MKELAJLE_00762 1.3e-165 yesQ P Binding-protein-dependent transport system inner membrane component
MKELAJLE_00763 1.6e-199 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
MKELAJLE_00764 0.0 yesS K Transcriptional regulator
MKELAJLE_00765 3.8e-133 E GDSL-like Lipase/Acylhydrolase
MKELAJLE_00766 8.9e-132 yesU S Domain of unknown function (DUF1961)
MKELAJLE_00767 1e-113 yesV S Protein of unknown function, DUF624
MKELAJLE_00768 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
MKELAJLE_00769 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
MKELAJLE_00770 3e-124 yesY E GDSL-like Lipase/Acylhydrolase
MKELAJLE_00771 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
MKELAJLE_00772 0.0 yetA
MKELAJLE_00773 9.6e-291 lplA G Bacterial extracellular solute-binding protein
MKELAJLE_00774 1.7e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
MKELAJLE_00775 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
MKELAJLE_00776 3.3e-258 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
MKELAJLE_00777 6.1e-123 yetF S membrane
MKELAJLE_00778 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
MKELAJLE_00779 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKELAJLE_00780 2.2e-34
MKELAJLE_00781 2.2e-89 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MKELAJLE_00782 4.4e-43 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MKELAJLE_00783 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
MKELAJLE_00784 5.3e-105 yetJ S Belongs to the BI1 family
MKELAJLE_00785 5.4e-159 yetK EG EamA-like transporter family
MKELAJLE_00786 6.4e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
MKELAJLE_00787 7.8e-213 yetM CH FAD binding domain
MKELAJLE_00788 3.6e-199 yetN S Protein of unknown function (DUF3900)
MKELAJLE_00789 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
MKELAJLE_00790 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MKELAJLE_00791 2.1e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
MKELAJLE_00792 1.9e-172 yfnG 4.2.1.45 M dehydratase
MKELAJLE_00793 3.8e-181 yfnF M Nucleotide-diphospho-sugar transferase
MKELAJLE_00794 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
MKELAJLE_00795 3.5e-190 yfnD M Nucleotide-diphospho-sugar transferase
MKELAJLE_00796 2e-206 fsr P COG0477 Permeases of the major facilitator superfamily
MKELAJLE_00797 7.8e-134 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MKELAJLE_00798 1.3e-241 yfnA E amino acid
MKELAJLE_00799 2.8e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MKELAJLE_00800 1.1e-113 yfmS NT chemotaxis protein
MKELAJLE_00801 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MKELAJLE_00802 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
MKELAJLE_00803 2.8e-70 yfmP K transcriptional
MKELAJLE_00804 1.5e-209 yfmO EGP Major facilitator Superfamily
MKELAJLE_00805 1.9e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MKELAJLE_00806 6.3e-202 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
MKELAJLE_00807 7.5e-82 yfmK 2.3.1.128 K acetyltransferase
MKELAJLE_00808 8.5e-190 yfmJ S N-terminal domain of oxidoreductase
MKELAJLE_00809 7.7e-214 G Major Facilitator Superfamily
MKELAJLE_00810 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
MKELAJLE_00811 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
MKELAJLE_00812 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKELAJLE_00813 4.3e-170 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKELAJLE_00814 3.4e-169 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
MKELAJLE_00815 2.9e-24 S Protein of unknown function (DUF3212)
MKELAJLE_00816 7.6e-58 yflT S Heat induced stress protein YflT
MKELAJLE_00817 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
MKELAJLE_00818 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
MKELAJLE_00819 1e-290 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MKELAJLE_00820 8.9e-119 citT T response regulator
MKELAJLE_00821 3e-181 yflP S Tripartite tricarboxylate transporter family receptor
MKELAJLE_00823 8.5e-227 citM C Citrate transporter
MKELAJLE_00824 5.5e-152 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
MKELAJLE_00825 1.3e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MKELAJLE_00826 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MKELAJLE_00827 9e-124 yflK S protein conserved in bacteria
MKELAJLE_00828 4e-18 yflJ S Protein of unknown function (DUF2639)
MKELAJLE_00829 4.1e-19 yflI
MKELAJLE_00830 2.4e-50 yflH S Protein of unknown function (DUF3243)
MKELAJLE_00831 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
MKELAJLE_00832 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MKELAJLE_00833 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MKELAJLE_00834 6e-67 yhdN S Domain of unknown function (DUF1992)
MKELAJLE_00835 3.2e-256 agcS_1 E Sodium alanine symporter
MKELAJLE_00836 1.6e-194 E Spore germination protein
MKELAJLE_00838 5.1e-207 yfkR S spore germination
MKELAJLE_00839 1.5e-283 yfkQ EG Spore germination protein
MKELAJLE_00840 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MKELAJLE_00841 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
MKELAJLE_00842 1.8e-133 treR K transcriptional
MKELAJLE_00843 1.6e-125 yfkO C nitroreductase
MKELAJLE_00844 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
MKELAJLE_00845 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
MKELAJLE_00846 6.8e-207 ydiM EGP Major facilitator Superfamily
MKELAJLE_00847 2.1e-29 yfkK S Belongs to the UPF0435 family
MKELAJLE_00848 2.2e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MKELAJLE_00849 8.4e-51 yfkI S gas vesicle protein
MKELAJLE_00850 9.7e-144 yihY S Belongs to the UPF0761 family
MKELAJLE_00851 5e-08
MKELAJLE_00852 6.9e-220 ycaD EGP COG0477 Permeases of the major facilitator superfamily
MKELAJLE_00853 6.1e-183 cax P COG0387 Ca2 H antiporter
MKELAJLE_00854 1.2e-146 yfkD S YfkD-like protein
MKELAJLE_00855 6e-149 yfkC M Mechanosensitive ion channel
MKELAJLE_00856 5.4e-222 yfkA S YfkB-like domain
MKELAJLE_00857 1.1e-26 yfjT
MKELAJLE_00858 2.6e-154 pdaA G deacetylase
MKELAJLE_00859 4.2e-150 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MKELAJLE_00860 1.7e-184 corA P Mediates influx of magnesium ions
MKELAJLE_00861 1e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MKELAJLE_00862 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MKELAJLE_00863 1.6e-39 S YfzA-like protein
MKELAJLE_00864 5.1e-192 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MKELAJLE_00865 3.9e-86 yfjM S Psort location Cytoplasmic, score
MKELAJLE_00866 3e-29 yfjL
MKELAJLE_00867 1.2e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MKELAJLE_00868 1e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MKELAJLE_00869 2.9e-197 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MKELAJLE_00870 6.4e-257 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MKELAJLE_00871 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
MKELAJLE_00872 1.2e-25 sspH S Belongs to the SspH family
MKELAJLE_00873 4e-56 yfjF S UPF0060 membrane protein
MKELAJLE_00874 1.3e-80 S Family of unknown function (DUF5381)
MKELAJLE_00875 1.8e-101 yfjD S Family of unknown function (DUF5381)
MKELAJLE_00876 4.1e-144 yfjC
MKELAJLE_00877 9.2e-191 yfjB
MKELAJLE_00878 1.1e-44 yfjA S Belongs to the WXG100 family
MKELAJLE_00879 9.9e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MKELAJLE_00880 3.2e-141 glvR K Helix-turn-helix domain, rpiR family
MKELAJLE_00881 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MKELAJLE_00882 2.1e-310 yfiB3 V ABC transporter
MKELAJLE_00883 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
MKELAJLE_00884 9.8e-65 mhqP S DoxX
MKELAJLE_00885 5.7e-163 yfiE 1.13.11.2 S glyoxalase
MKELAJLE_00886 1.5e-177 K AraC-like ligand binding domain
MKELAJLE_00887 1.8e-262 iolT EGP Major facilitator Superfamily
MKELAJLE_00888 8.4e-184 G Xylose isomerase
MKELAJLE_00889 1.1e-233 S Oxidoreductase
MKELAJLE_00891 1.1e-214 yxjM T Histidine kinase
MKELAJLE_00892 3.2e-113 KT LuxR family transcriptional regulator
MKELAJLE_00893 6.2e-171 V ABC transporter, ATP-binding protein
MKELAJLE_00894 9.8e-214 V ABC-2 family transporter protein
MKELAJLE_00895 4.6e-208 V COG0842 ABC-type multidrug transport system, permease component
MKELAJLE_00896 8.3e-99 padR K transcriptional
MKELAJLE_00897 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
MKELAJLE_00898 9e-198 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MKELAJLE_00899 2e-109 yfiR K Transcriptional regulator
MKELAJLE_00900 5.1e-221 yfiS EGP Major facilitator Superfamily
MKELAJLE_00901 3.3e-100 yfiT S Belongs to the metal hydrolase YfiT family
MKELAJLE_00902 8.7e-287 yfiU EGP Major facilitator Superfamily
MKELAJLE_00903 3.1e-81 yfiV K transcriptional
MKELAJLE_00904 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MKELAJLE_00905 6.2e-182 yfiY P ABC transporter substrate-binding protein
MKELAJLE_00906 3.1e-176 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKELAJLE_00907 5.2e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKELAJLE_00908 1.8e-167 yfhB 5.3.3.17 S PhzF family
MKELAJLE_00909 3.9e-107 yfhC C nitroreductase
MKELAJLE_00910 2.1e-25 yfhD S YfhD-like protein
MKELAJLE_00912 4.9e-173 yfhF S nucleoside-diphosphate sugar epimerase
MKELAJLE_00913 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
MKELAJLE_00914 9.7e-52 yfhH S Protein of unknown function (DUF1811)
MKELAJLE_00916 1.1e-209 yfhI EGP Major facilitator Superfamily
MKELAJLE_00917 6.2e-20 sspK S reproduction
MKELAJLE_00918 1.3e-44 yfhJ S WVELL protein
MKELAJLE_00919 9.2e-92 batE T Bacterial SH3 domain homologues
MKELAJLE_00920 3.5e-51 yfhL S SdpI/YhfL protein family
MKELAJLE_00921 6.7e-172 yfhM S Alpha beta hydrolase
MKELAJLE_00922 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MKELAJLE_00923 0.0 yfhO S Bacterial membrane protein YfhO
MKELAJLE_00924 5.5e-186 yfhP S membrane-bound metal-dependent
MKELAJLE_00925 7.8e-212 mutY L A G-specific
MKELAJLE_00926 6.9e-36 yfhS
MKELAJLE_00927 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKELAJLE_00928 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
MKELAJLE_00929 4.9e-48 ygaB S YgaB-like protein
MKELAJLE_00930 1.3e-104 ygaC J Belongs to the UPF0374 family
MKELAJLE_00931 1.8e-301 ygaD V ABC transporter
MKELAJLE_00932 8.7e-180 ygaE S Membrane
MKELAJLE_00933 1.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
MKELAJLE_00934 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
MKELAJLE_00935 4e-80 perR P Belongs to the Fur family
MKELAJLE_00936 1.5e-56 ygzB S UPF0295 protein
MKELAJLE_00937 6.7e-167 ygxA S Nucleotidyltransferase-like
MKELAJLE_00938 3.4e-39 S COG NOG14552 non supervised orthologous group
MKELAJLE_00943 7.8e-08
MKELAJLE_00951 2e-08
MKELAJLE_00955 2.7e-143 spo0M S COG4326 Sporulation control protein
MKELAJLE_00956 3e-27
MKELAJLE_00957 5.9e-134 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
MKELAJLE_00959 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MKELAJLE_00960 1.9e-266 ygaK C Berberine and berberine like
MKELAJLE_00962 3.2e-291 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
MKELAJLE_00963 1.1e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MKELAJLE_00964 1.7e-171 ssuA M Sulfonate ABC transporter
MKELAJLE_00965 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MKELAJLE_00966 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
MKELAJLE_00968 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MKELAJLE_00969 4.1e-78 ygaO
MKELAJLE_00970 4.4e-29 K Transcriptional regulator
MKELAJLE_00972 7.9e-114 yhzB S B3/4 domain
MKELAJLE_00973 2.1e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MKELAJLE_00974 4.4e-177 yhbB S Putative amidase domain
MKELAJLE_00975 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MKELAJLE_00976 1.2e-109 yhbD K Protein of unknown function (DUF4004)
MKELAJLE_00977 1.6e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
MKELAJLE_00978 8.2e-75 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
MKELAJLE_00979 0.0 prkA T Ser protein kinase
MKELAJLE_00980 2.5e-225 yhbH S Belongs to the UPF0229 family
MKELAJLE_00981 2.2e-76 yhbI K DNA-binding transcription factor activity
MKELAJLE_00982 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
MKELAJLE_00983 3.1e-271 yhcA EGP Major facilitator Superfamily
MKELAJLE_00984 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
MKELAJLE_00985 2.8e-37 yhcC
MKELAJLE_00986 7.8e-55
MKELAJLE_00987 6.6e-60 yhcF K Transcriptional regulator
MKELAJLE_00988 1.6e-123 yhcG V ABC transporter, ATP-binding protein
MKELAJLE_00989 2.6e-166 yhcH V ABC transporter, ATP-binding protein
MKELAJLE_00990 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MKELAJLE_00991 1e-30 cspB K Cold-shock protein
MKELAJLE_00992 5.2e-153 metQ M Belongs to the nlpA lipoprotein family
MKELAJLE_00993 1.2e-197 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
MKELAJLE_00994 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MKELAJLE_00995 3.7e-44 yhcM
MKELAJLE_00996 2.1e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MKELAJLE_00997 2.5e-167 yhcP
MKELAJLE_00998 5.2e-100 yhcQ M Spore coat protein
MKELAJLE_00999 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
MKELAJLE_01000 7.6e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
MKELAJLE_01001 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MKELAJLE_01002 9.3e-68 yhcU S Family of unknown function (DUF5365)
MKELAJLE_01003 9.9e-68 yhcV S COG0517 FOG CBS domain
MKELAJLE_01004 4.6e-120 yhcW 5.4.2.6 S hydrolase
MKELAJLE_01005 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MKELAJLE_01006 1.1e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MKELAJLE_01007 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MKELAJLE_01008 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
MKELAJLE_01009 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MKELAJLE_01010 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MKELAJLE_01011 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
MKELAJLE_01012 5.5e-214 yhcY 2.7.13.3 T Histidine kinase
MKELAJLE_01013 1.1e-113 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKELAJLE_01014 1.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
MKELAJLE_01015 1.2e-38 yhdB S YhdB-like protein
MKELAJLE_01016 4.8e-54 yhdC S Protein of unknown function (DUF3889)
MKELAJLE_01017 7.9e-189 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MKELAJLE_01018 3.5e-76 nsrR K Transcriptional regulator
MKELAJLE_01019 8.7e-239 ygxB M Conserved TM helix
MKELAJLE_01020 2.1e-276 ycgB S Stage V sporulation protein R
MKELAJLE_01021 5.8e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
MKELAJLE_01022 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MKELAJLE_01023 3.8e-162 citR K Transcriptional regulator
MKELAJLE_01024 1.4e-206 citA 2.3.3.1 C Belongs to the citrate synthase family
MKELAJLE_01025 4.9e-162 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKELAJLE_01026 3.4e-250 yhdG E amino acid
MKELAJLE_01027 1.5e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MKELAJLE_01028 3.7e-276 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MKELAJLE_01029 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKELAJLE_01030 8.1e-45 yhdK S Sigma-M inhibitor protein
MKELAJLE_01031 6.6e-201 yhdL S Sigma factor regulator N-terminal
MKELAJLE_01032 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
MKELAJLE_01033 1.5e-191 yhdN C Aldo keto reductase
MKELAJLE_01034 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MKELAJLE_01035 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MKELAJLE_01036 4.1e-74 cueR K transcriptional
MKELAJLE_01037 1.4e-223 yhdR 2.6.1.1 E Aminotransferase
MKELAJLE_01038 1.1e-240 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
MKELAJLE_01039 2.8e-47 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MKELAJLE_01040 5.1e-66 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MKELAJLE_01041 3.3e-135 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MKELAJLE_01043 6.6e-204 yhdY M Mechanosensitive ion channel
MKELAJLE_01044 1.2e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MKELAJLE_01045 1.7e-151 yheN G deacetylase
MKELAJLE_01046 1.1e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
MKELAJLE_01047 2.2e-233 nhaC C Na H antiporter
MKELAJLE_01048 3.4e-84 nhaX T Belongs to the universal stress protein A family
MKELAJLE_01049 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
MKELAJLE_01050 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
MKELAJLE_01051 3.7e-111 yheG GM NAD(P)H-binding
MKELAJLE_01052 6.3e-28 sspB S spore protein
MKELAJLE_01053 1.3e-36 yheE S Family of unknown function (DUF5342)
MKELAJLE_01054 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
MKELAJLE_01055 4.3e-216 yheC HJ YheC/D like ATP-grasp
MKELAJLE_01056 6.7e-204 yheB S Belongs to the UPF0754 family
MKELAJLE_01057 9.5e-48 yheA S Belongs to the UPF0342 family
MKELAJLE_01058 3.1e-206 yhaZ L DNA alkylation repair enzyme
MKELAJLE_01059 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
MKELAJLE_01060 7.1e-294 hemZ H coproporphyrinogen III oxidase
MKELAJLE_01061 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
MKELAJLE_01062 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
MKELAJLE_01064 1.9e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
MKELAJLE_01065 1.1e-26 S YhzD-like protein
MKELAJLE_01066 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
MKELAJLE_01067 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
MKELAJLE_01068 3.6e-227 yhaO L DNA repair exonuclease
MKELAJLE_01069 0.0 yhaN L AAA domain
MKELAJLE_01070 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
MKELAJLE_01071 1.6e-21 yhaL S Sporulation protein YhaL
MKELAJLE_01072 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MKELAJLE_01073 8.7e-90 yhaK S Putative zincin peptidase
MKELAJLE_01074 1.3e-54 yhaI S Protein of unknown function (DUF1878)
MKELAJLE_01075 1e-113 hpr K Negative regulator of protease production and sporulation
MKELAJLE_01076 7e-39 yhaH S YtxH-like protein
MKELAJLE_01077 3.6e-80 trpP S Tryptophan transporter TrpP
MKELAJLE_01078 9.9e-205 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MKELAJLE_01079 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MKELAJLE_01080 4.6e-137 ecsA V transporter (ATP-binding protein)
MKELAJLE_01081 1.8e-215 ecsB U ABC transporter
MKELAJLE_01082 4.8e-115 ecsC S EcsC protein family
MKELAJLE_01083 2.3e-231 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MKELAJLE_01084 4.2e-248 yhfA C membrane
MKELAJLE_01085 7.5e-17 1.15.1.2 C Rubrerythrin
MKELAJLE_01086 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
MKELAJLE_01087 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MKELAJLE_01088 1.7e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MKELAJLE_01089 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
MKELAJLE_01090 1.7e-268 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MKELAJLE_01091 1.4e-101 yhgD K Transcriptional regulator
MKELAJLE_01092 1e-238 yhgE S YhgE Pip N-terminal domain protein
MKELAJLE_01093 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MKELAJLE_01094 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
MKELAJLE_01095 1.6e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
MKELAJLE_01096 1.7e-72 3.4.13.21 S ASCH
MKELAJLE_01097 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MKELAJLE_01098 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
MKELAJLE_01099 2e-191 lplJ 6.3.1.20 H Lipoate-protein ligase
MKELAJLE_01100 2.6e-112 yhfK GM NmrA-like family
MKELAJLE_01101 7.3e-302 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
MKELAJLE_01102 1.9e-65 yhfM
MKELAJLE_01103 5.4e-242 yhfN 3.4.24.84 O Peptidase M48
MKELAJLE_01104 2.3e-204 aprE 3.4.21.62 O Belongs to the peptidase S8 family
MKELAJLE_01105 9.2e-80 VY92_01935 K acetyltransferase
MKELAJLE_01106 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
MKELAJLE_01107 4.3e-159 yfmC M Periplasmic binding protein
MKELAJLE_01108 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
MKELAJLE_01109 2.3e-201 vraB 2.3.1.9 I Belongs to the thiolase family
MKELAJLE_01110 1e-281 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
MKELAJLE_01111 5e-91 bioY S BioY family
MKELAJLE_01112 1.7e-182 hemAT NT chemotaxis protein
MKELAJLE_01113 1.1e-302 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
MKELAJLE_01114 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKELAJLE_01115 1.3e-32 yhzC S IDEAL
MKELAJLE_01116 4.2e-109 comK K Competence transcription factor
MKELAJLE_01117 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
MKELAJLE_01118 7.8e-42 yhjA S Excalibur calcium-binding domain
MKELAJLE_01119 6.1e-266 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MKELAJLE_01120 6.9e-27 yhjC S Protein of unknown function (DUF3311)
MKELAJLE_01121 5e-60 yhjD
MKELAJLE_01122 9.1e-110 yhjE S SNARE associated Golgi protein
MKELAJLE_01123 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
MKELAJLE_01124 1.1e-286 yhjG CH FAD binding domain
MKELAJLE_01125 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
MKELAJLE_01126 6.9e-215 glcP G Major Facilitator Superfamily
MKELAJLE_01127 1.1e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
MKELAJLE_01128 1.8e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
MKELAJLE_01129 4.4e-255 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
MKELAJLE_01130 7e-189 yhjM 5.1.1.1 K Transcriptional regulator
MKELAJLE_01131 3.8e-202 abrB S membrane
MKELAJLE_01132 3.1e-215 EGP Transmembrane secretion effector
MKELAJLE_01133 0.0 S Sugar transport-related sRNA regulator N-term
MKELAJLE_01134 2e-36 yhjQ C COG1145 Ferredoxin
MKELAJLE_01135 2.2e-78 yhjR S Rubrerythrin
MKELAJLE_01136 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
MKELAJLE_01137 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MKELAJLE_01138 1.7e-221 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MKELAJLE_01139 0.0 sbcC L COG0419 ATPase involved in DNA repair
MKELAJLE_01140 6e-51 yisB V COG1403 Restriction endonuclease
MKELAJLE_01141 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
MKELAJLE_01142 3e-66 gerPE S Spore germination protein GerPE
MKELAJLE_01143 6.3e-24 gerPD S Spore germination protein
MKELAJLE_01144 1.8e-54 gerPC S Spore germination protein
MKELAJLE_01145 4e-34 gerPB S cell differentiation
MKELAJLE_01146 1.9e-33 gerPA S Spore germination protein
MKELAJLE_01147 1.5e-22 yisI S Spo0E like sporulation regulatory protein
MKELAJLE_01148 1.7e-176 cotH M Spore Coat
MKELAJLE_01149 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MKELAJLE_01150 3e-57 yisL S UPF0344 protein
MKELAJLE_01151 0.0 wprA O Belongs to the peptidase S8 family
MKELAJLE_01152 7.2e-106 yisN S Protein of unknown function (DUF2777)
MKELAJLE_01153 0.0 asnO 6.3.5.4 E Asparagine synthase
MKELAJLE_01154 2.1e-88 yizA S Damage-inducible protein DinB
MKELAJLE_01155 6.8e-150 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
MKELAJLE_01156 4e-243 yisQ V Mate efflux family protein
MKELAJLE_01157 1.2e-160 yisR K Transcriptional regulator
MKELAJLE_01158 2.4e-184 purR K helix_turn _helix lactose operon repressor
MKELAJLE_01159 4.5e-199 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
MKELAJLE_01160 1.3e-93 yisT S DinB family
MKELAJLE_01161 6.4e-108 argO S Lysine exporter protein LysE YggA
MKELAJLE_01162 1.7e-281 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MKELAJLE_01163 4e-36 mcbG S Pentapeptide repeats (9 copies)
MKELAJLE_01164 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MKELAJLE_01165 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
MKELAJLE_01166 3.2e-233 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
MKELAJLE_01167 9.2e-143 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
MKELAJLE_01168 4.9e-125 comB 3.1.3.71 H Belongs to the ComB family
MKELAJLE_01169 1.9e-141 yitD 4.4.1.19 S synthase
MKELAJLE_01170 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MKELAJLE_01171 5.4e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MKELAJLE_01172 4e-229 yitG EGP Major facilitator Superfamily
MKELAJLE_01173 1.8e-161 yitH K Acetyltransferase (GNAT) domain
MKELAJLE_01174 2e-82 yjcF S Acetyltransferase (GNAT) domain
MKELAJLE_01175 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MKELAJLE_01176 8.6e-55 yajQ S Belongs to the UPF0234 family
MKELAJLE_01177 4e-161 cvfB S protein conserved in bacteria
MKELAJLE_01178 8.5e-94
MKELAJLE_01179 2.8e-171
MKELAJLE_01180 1.5e-97 S Sporulation delaying protein SdpA
MKELAJLE_01181 1.5e-58 K Transcriptional regulator PadR-like family
MKELAJLE_01182 2e-95
MKELAJLE_01183 1.4e-44 yitR S Domain of unknown function (DUF3784)
MKELAJLE_01184 2.2e-311 nprB 3.4.24.28 E Peptidase M4
MKELAJLE_01185 1.5e-155 yitS S protein conserved in bacteria
MKELAJLE_01186 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
MKELAJLE_01187 1.9e-72 ipi S Intracellular proteinase inhibitor
MKELAJLE_01188 1.2e-17 S Protein of unknown function (DUF3813)
MKELAJLE_01189 1.9e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
MKELAJLE_01190 4.5e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
MKELAJLE_01191 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
MKELAJLE_01192 1.5e-22 pilT S Proteolipid membrane potential modulator
MKELAJLE_01193 4.3e-272 yitY C D-arabinono-1,4-lactone oxidase
MKELAJLE_01194 1.7e-88 norB G Major Facilitator Superfamily
MKELAJLE_01195 5.4e-200 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MKELAJLE_01196 3.1e-231 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MKELAJLE_01197 2.2e-137 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
MKELAJLE_01198 4.4e-219 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
MKELAJLE_01199 3.9e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MKELAJLE_01200 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
MKELAJLE_01201 3.8e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MKELAJLE_01202 9.5e-28 yjzC S YjzC-like protein
MKELAJLE_01203 2.3e-16 yjzD S Protein of unknown function (DUF2929)
MKELAJLE_01204 6.2e-142 yjaU I carboxylic ester hydrolase activity
MKELAJLE_01205 7.3e-103 yjaV
MKELAJLE_01206 1.1e-183 med S Transcriptional activator protein med
MKELAJLE_01207 7.3e-26 comZ S ComZ
MKELAJLE_01208 2.7e-22 yjzB
MKELAJLE_01209 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MKELAJLE_01210 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MKELAJLE_01211 7.8e-151 yjaZ O Zn-dependent protease
MKELAJLE_01212 1.8e-184 appD P Belongs to the ABC transporter superfamily
MKELAJLE_01213 6.5e-187 appF E Belongs to the ABC transporter superfamily
MKELAJLE_01214 1.6e-251 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
MKELAJLE_01215 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKELAJLE_01216 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKELAJLE_01217 5e-147 yjbA S Belongs to the UPF0736 family
MKELAJLE_01218 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
MKELAJLE_01219 0.0 oppA E ABC transporter substrate-binding protein
MKELAJLE_01220 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKELAJLE_01221 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKELAJLE_01222 3e-198 oppD P Belongs to the ABC transporter superfamily
MKELAJLE_01223 5.5e-172 oppF E Belongs to the ABC transporter superfamily
MKELAJLE_01224 8.6e-196 yjbB EGP Major Facilitator Superfamily
MKELAJLE_01225 6.9e-104 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKELAJLE_01226 2.1e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MKELAJLE_01227 6e-112 yjbE P Integral membrane protein TerC family
MKELAJLE_01228 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MKELAJLE_01229 2.3e-223 yjbF S Competence protein
MKELAJLE_01230 0.0 pepF E oligoendopeptidase F
MKELAJLE_01231 1.8e-20
MKELAJLE_01233 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
MKELAJLE_01234 3.7e-72 yjbI S Bacterial-like globin
MKELAJLE_01235 1.5e-87 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MKELAJLE_01236 2.4e-101 yjbK S protein conserved in bacteria
MKELAJLE_01237 7.1e-62 yjbL S Belongs to the UPF0738 family
MKELAJLE_01238 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
MKELAJLE_01239 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MKELAJLE_01240 9.5e-161 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MKELAJLE_01241 3e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
MKELAJLE_01242 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MKELAJLE_01243 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MKELAJLE_01244 3.8e-108 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
MKELAJLE_01245 7.2e-219 thiO 1.4.3.19 E Glycine oxidase
MKELAJLE_01246 3e-30 thiS H thiamine diphosphate biosynthetic process
MKELAJLE_01247 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MKELAJLE_01248 6e-188 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MKELAJLE_01249 5.3e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MKELAJLE_01250 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
MKELAJLE_01251 5.9e-54 yjbX S Spore coat protein
MKELAJLE_01252 5.2e-83 cotZ S Spore coat protein
MKELAJLE_01253 3.4e-96 cotY S Spore coat protein Z
MKELAJLE_01254 6.4e-77 cotX S Spore Coat Protein X and V domain
MKELAJLE_01255 3e-32 cotW
MKELAJLE_01256 2.3e-55 cotV S Spore Coat Protein X and V domain
MKELAJLE_01257 8.7e-57 yjcA S Protein of unknown function (DUF1360)
MKELAJLE_01260 2.9e-38 spoVIF S Stage VI sporulation protein F
MKELAJLE_01261 0.0 yjcD 3.6.4.12 L DNA helicase
MKELAJLE_01262 1.7e-38
MKELAJLE_01263 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKELAJLE_01264 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
MKELAJLE_01265 1.8e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
MKELAJLE_01266 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MKELAJLE_01267 2.9e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MKELAJLE_01268 3.7e-99 rimJ 2.3.1.128 J Alanine acetyltransferase
MKELAJLE_01269 1.1e-212 yjcL S Protein of unknown function (DUF819)
MKELAJLE_01272 2.1e-190 S Putative amidase domain
MKELAJLE_01273 2.6e-44 yjcN
MKELAJLE_01276 8.5e-81 L Transposase
MKELAJLE_01277 1.6e-72 yjcP
MKELAJLE_01278 4.1e-49 S YjcQ protein
MKELAJLE_01279 1.1e-92 yqaS L DNA packaging
MKELAJLE_01280 2.2e-47 yjcS S Antibiotic biosynthesis monooxygenase
MKELAJLE_01281 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
MKELAJLE_01283 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
MKELAJLE_01284 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
MKELAJLE_01285 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
MKELAJLE_01286 4.8e-51 yjdF S Protein of unknown function (DUF2992)
MKELAJLE_01287 2.5e-94 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
MKELAJLE_01289 8e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MKELAJLE_01290 4.2e-29 S Domain of unknown function (DUF4177)
MKELAJLE_01291 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
MKELAJLE_01292 3.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MKELAJLE_01294 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
MKELAJLE_01295 5.5e-83 S Protein of unknown function (DUF2690)
MKELAJLE_01296 3.6e-21 yjfB S Putative motility protein
MKELAJLE_01297 1.6e-171 yjfC O Predicted Zn-dependent protease (DUF2268)
MKELAJLE_01298 1.2e-45 T PhoQ Sensor
MKELAJLE_01299 8.9e-104 yjgB S Domain of unknown function (DUF4309)
MKELAJLE_01300 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
MKELAJLE_01301 4.3e-95 yjgD S Protein of unknown function (DUF1641)
MKELAJLE_01302 8.7e-07 S Domain of unknown function (DUF4352)
MKELAJLE_01303 2e-117 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
MKELAJLE_01305 3.8e-226 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
MKELAJLE_01306 4.5e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MKELAJLE_01307 8.2e-30
MKELAJLE_01308 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
MKELAJLE_01309 1.9e-122 ybbM S transport system, permease component
MKELAJLE_01310 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
MKELAJLE_01311 1.8e-176 yjlA EG Putative multidrug resistance efflux transporter
MKELAJLE_01312 2.8e-93 yjlB S Cupin domain
MKELAJLE_01313 7.1e-66 yjlC S Protein of unknown function (DUF1641)
MKELAJLE_01314 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
MKELAJLE_01315 6.3e-284 uxaC 5.3.1.12 G glucuronate isomerase
MKELAJLE_01316 5.8e-250 yjmB G symporter YjmB
MKELAJLE_01317 3e-195 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
MKELAJLE_01318 1.6e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
MKELAJLE_01319 4.7e-215 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
MKELAJLE_01320 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MKELAJLE_01321 3.7e-227 exuT G Sugar (and other) transporter
MKELAJLE_01322 2.3e-184 exuR K transcriptional
MKELAJLE_01323 2.1e-287 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
MKELAJLE_01324 2e-288 uxaA 4.2.1.7, 4.4.1.24 G Altronate
MKELAJLE_01325 4.3e-130 MA20_18170 S membrane transporter protein
MKELAJLE_01326 3.3e-80 yjoA S DinB family
MKELAJLE_01327 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
MKELAJLE_01328 2.1e-213 S response regulator aspartate phosphatase
MKELAJLE_01330 6.3e-41 S YCII-related domain
MKELAJLE_01331 9.1e-170 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
MKELAJLE_01332 2.1e-61 yjqA S Bacterial PH domain
MKELAJLE_01333 4.2e-112 yjqB S Pfam:DUF867
MKELAJLE_01334 4.4e-160 ydbD P Catalase
MKELAJLE_01335 1.6e-111 xkdA E IrrE N-terminal-like domain
MKELAJLE_01336 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
MKELAJLE_01338 5.9e-157 xkdB K sequence-specific DNA binding
MKELAJLE_01339 6.4e-119 xkdC L Bacterial dnaA protein
MKELAJLE_01342 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
MKELAJLE_01343 4.4e-86 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MKELAJLE_01344 4.8e-140 xtmA L phage terminase small subunit
MKELAJLE_01345 9.6e-255 xtmB S phage terminase, large subunit
MKELAJLE_01346 5.4e-286 yqbA S portal protein
MKELAJLE_01347 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
MKELAJLE_01348 5.8e-169 xkdG S Phage capsid family
MKELAJLE_01349 5.5e-65 yqbG S Protein of unknown function (DUF3199)
MKELAJLE_01350 8.7e-65 yqbH S Domain of unknown function (DUF3599)
MKELAJLE_01351 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
MKELAJLE_01352 1.9e-77 xkdJ
MKELAJLE_01353 2.5e-256 xkdK S Phage tail sheath C-terminal domain
MKELAJLE_01354 6.1e-76 xkdM S Phage tail tube protein
MKELAJLE_01355 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
MKELAJLE_01356 0.0 xkdO L Transglycosylase SLT domain
MKELAJLE_01357 3.7e-122 xkdP S Lysin motif
MKELAJLE_01358 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
MKELAJLE_01359 2.1e-39 xkdR S Protein of unknown function (DUF2577)
MKELAJLE_01360 9.6e-71 xkdS S Protein of unknown function (DUF2634)
MKELAJLE_01361 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MKELAJLE_01362 4e-104 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
MKELAJLE_01363 6.7e-41
MKELAJLE_01364 0.0
MKELAJLE_01365 2.6e-55 xkdW S XkdW protein
MKELAJLE_01366 1.7e-23 xkdX
MKELAJLE_01367 1.2e-154 xepA
MKELAJLE_01368 2.8e-39 xhlA S Haemolysin XhlA
MKELAJLE_01369 9.3e-40 xhlB S SPP1 phage holin
MKELAJLE_01370 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MKELAJLE_01371 6.7e-23 spoIISB S Stage II sporulation protein SB
MKELAJLE_01372 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
MKELAJLE_01373 5.8e-175 pit P phosphate transporter
MKELAJLE_01374 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
MKELAJLE_01375 9.4e-242 steT E amino acid
MKELAJLE_01376 7.2e-183 mhqA E COG0346 Lactoylglutathione lyase and related lyases
MKELAJLE_01378 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MKELAJLE_01379 1.3e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MKELAJLE_01381 8.5e-214 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MKELAJLE_01382 1e-137 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
MKELAJLE_01383 7.9e-154 dppA E D-aminopeptidase
MKELAJLE_01384 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKELAJLE_01385 3.9e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKELAJLE_01386 3.4e-191 dppD P Belongs to the ABC transporter superfamily
MKELAJLE_01387 0.0 dppE E ABC transporter substrate-binding protein
MKELAJLE_01389 8.1e-179 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
MKELAJLE_01390 3.2e-203 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MKELAJLE_01391 5.3e-172 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MKELAJLE_01392 7.7e-188 ykfD E Belongs to the ABC transporter superfamily
MKELAJLE_01393 7.4e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
MKELAJLE_01394 5.3e-161 ykgA E Amidinotransferase
MKELAJLE_01395 1.5e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
MKELAJLE_01396 1e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MKELAJLE_01397 1e-07
MKELAJLE_01398 5.4e-130 ykjA S Protein of unknown function (DUF421)
MKELAJLE_01399 1e-98 ykkA S Protein of unknown function (DUF664)
MKELAJLE_01400 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MKELAJLE_01401 3.5e-55 ykkC P Multidrug resistance protein
MKELAJLE_01402 1.1e-50 ykkD P Multidrug resistance protein
MKELAJLE_01403 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
MKELAJLE_01404 1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MKELAJLE_01405 2.5e-228 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MKELAJLE_01406 1.3e-70 ohrA O Organic hydroperoxide resistance protein
MKELAJLE_01407 3.9e-75 ohrR K COG1846 Transcriptional regulators
MKELAJLE_01408 8.4e-72 ohrB O Organic hydroperoxide resistance protein
MKELAJLE_01410 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
MKELAJLE_01411 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MKELAJLE_01412 1.7e-176 isp O Belongs to the peptidase S8 family
MKELAJLE_01413 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MKELAJLE_01414 1.8e-136 ykoC P Cobalt transport protein
MKELAJLE_01415 4.6e-311 P ABC transporter, ATP-binding protein
MKELAJLE_01416 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
MKELAJLE_01417 7.9e-111 ykoF S YKOF-related Family
MKELAJLE_01418 2.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKELAJLE_01419 9.4e-245 ykoH 2.7.13.3 T Histidine kinase
MKELAJLE_01420 1.1e-113 ykoI S Peptidase propeptide and YPEB domain
MKELAJLE_01421 4.4e-86 ykoJ S Peptidase propeptide and YPEB domain
MKELAJLE_01424 2.2e-222 mgtE P Acts as a magnesium transporter
MKELAJLE_01425 1.4e-53 tnrA K transcriptional
MKELAJLE_01426 5.9e-18
MKELAJLE_01427 6.9e-26 ykoL
MKELAJLE_01428 1.3e-81 mhqR K transcriptional
MKELAJLE_01429 2.3e-220 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
MKELAJLE_01430 3.7e-99 ykoP G polysaccharide deacetylase
MKELAJLE_01431 7.1e-155 ykoQ S Calcineurin-like phosphoesterase superfamily domain
MKELAJLE_01432 0.0 ykoS
MKELAJLE_01433 2.5e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MKELAJLE_01434 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
MKELAJLE_01435 3.2e-161 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MKELAJLE_01436 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
MKELAJLE_01437 1.4e-116 ykoX S membrane-associated protein
MKELAJLE_01438 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MKELAJLE_01439 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKELAJLE_01440 8.2e-117 rsgI S Anti-sigma factor N-terminus
MKELAJLE_01441 1.9e-26 sspD S small acid-soluble spore protein
MKELAJLE_01442 1.5e-124 ykrK S Domain of unknown function (DUF1836)
MKELAJLE_01443 7e-156 htpX O Belongs to the peptidase M48B family
MKELAJLE_01444 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
MKELAJLE_01445 1.2e-10 ydfR S Protein of unknown function (DUF421)
MKELAJLE_01446 4.5e-22 ykzE
MKELAJLE_01447 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
MKELAJLE_01448 0.0 kinE 2.7.13.3 T Histidine kinase
MKELAJLE_01449 7e-89 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MKELAJLE_01451 3.3e-197 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MKELAJLE_01452 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MKELAJLE_01453 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MKELAJLE_01454 8e-232 mtnE 2.6.1.83 E Aminotransferase
MKELAJLE_01455 4.1e-231 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
MKELAJLE_01456 7.5e-137 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MKELAJLE_01457 7.2e-115 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
MKELAJLE_01458 1.3e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MKELAJLE_01459 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
MKELAJLE_01460 6.4e-09 S Spo0E like sporulation regulatory protein
MKELAJLE_01461 1.4e-64 eag
MKELAJLE_01462 2.5e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
MKELAJLE_01463 1.3e-75 ykvE K transcriptional
MKELAJLE_01464 2.5e-125 motB N Flagellar motor protein
MKELAJLE_01465 2.7e-138 motA N flagellar motor
MKELAJLE_01466 0.0 clpE O Belongs to the ClpA ClpB family
MKELAJLE_01467 8.7e-182 ykvI S membrane
MKELAJLE_01468 7.3e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MKELAJLE_01469 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
MKELAJLE_01470 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MKELAJLE_01471 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MKELAJLE_01472 2e-61 ykvN K Transcriptional regulator
MKELAJLE_01473 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
MKELAJLE_01474 4e-217 ykvP 3.5.1.28 M Glycosyl transferases group 1
MKELAJLE_01475 1.2e-35 3.5.1.104 M LysM domain
MKELAJLE_01476 8.5e-133 G Glycosyl hydrolases family 18
MKELAJLE_01477 5.6e-46 ykvR S Protein of unknown function (DUF3219)
MKELAJLE_01478 6e-25 ykvS S protein conserved in bacteria
MKELAJLE_01479 2.8e-28
MKELAJLE_01480 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
MKELAJLE_01481 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MKELAJLE_01482 4.9e-90 stoA CO thiol-disulfide
MKELAJLE_01483 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
MKELAJLE_01484 3.8e-09
MKELAJLE_01485 8.7e-209 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
MKELAJLE_01487 9.8e-180 ykvZ 5.1.1.1 K Transcriptional regulator
MKELAJLE_01489 4.5e-128 glcT K antiterminator
MKELAJLE_01490 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MKELAJLE_01491 2.1e-39 ptsH G phosphocarrier protein HPr
MKELAJLE_01492 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MKELAJLE_01493 7.2e-39 splA S Transcriptional regulator
MKELAJLE_01494 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
MKELAJLE_01495 1.2e-131 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKELAJLE_01496 2e-264 mcpC NT chemotaxis protein
MKELAJLE_01497 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MKELAJLE_01498 8e-124 ykwD J protein with SCP PR1 domains
MKELAJLE_01499 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
MKELAJLE_01500 0.0 pilS 2.7.13.3 T Histidine kinase
MKELAJLE_01501 8e-224 patA 2.6.1.1 E Aminotransferase
MKELAJLE_01502 2.2e-15
MKELAJLE_01503 1.6e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
MKELAJLE_01504 1.7e-84 ykyB S YkyB-like protein
MKELAJLE_01505 1.6e-238 ykuC EGP Major facilitator Superfamily
MKELAJLE_01506 4.6e-88 ykuD S protein conserved in bacteria
MKELAJLE_01507 9.4e-166 ykuE S Metallophosphoesterase
MKELAJLE_01508 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKELAJLE_01509 0.0 3.2.1.132 M Putative peptidoglycan binding domain
MKELAJLE_01510 1.7e-93 M Peptidoglycan-binding domain 1 protein
MKELAJLE_01512 5.2e-234 ykuI T Diguanylate phosphodiesterase
MKELAJLE_01513 3.9e-37 ykuJ S protein conserved in bacteria
MKELAJLE_01514 4.4e-94 ykuK S Ribonuclease H-like
MKELAJLE_01515 3.9e-27 ykzF S Antirepressor AbbA
MKELAJLE_01516 1.6e-76 ykuL S CBS domain
MKELAJLE_01517 3.5e-168 ccpC K Transcriptional regulator
MKELAJLE_01518 5.7e-88 fld C Flavodoxin domain
MKELAJLE_01519 3.2e-177 ykuO
MKELAJLE_01520 3.2e-80 fld C Flavodoxin
MKELAJLE_01521 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MKELAJLE_01522 5.8e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MKELAJLE_01523 9e-37 ykuS S Belongs to the UPF0180 family
MKELAJLE_01524 8.8e-142 ykuT M Mechanosensitive ion channel
MKELAJLE_01525 3.9e-101 ykuU O Alkyl hydroperoxide reductase
MKELAJLE_01526 4.4e-82 ykuV CO thiol-disulfide
MKELAJLE_01527 5.8e-95 rok K Repressor of ComK
MKELAJLE_01528 2.9e-147 yknT
MKELAJLE_01529 3.9e-110 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MKELAJLE_01530 5.3e-192 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MKELAJLE_01531 8.1e-246 moeA 2.10.1.1 H molybdopterin
MKELAJLE_01532 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
MKELAJLE_01533 8.5e-84 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
MKELAJLE_01534 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MKELAJLE_01535 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
MKELAJLE_01536 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
MKELAJLE_01537 1e-117 yknW S Yip1 domain
MKELAJLE_01538 3e-159 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MKELAJLE_01539 2.5e-124 macB V ABC transporter, ATP-binding protein
MKELAJLE_01540 2.1e-211 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
MKELAJLE_01541 3.1e-136 fruR K Transcriptional regulator
MKELAJLE_01542 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
MKELAJLE_01543 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MKELAJLE_01544 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MKELAJLE_01545 8.1e-39 ykoA
MKELAJLE_01546 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MKELAJLE_01547 1.5e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MKELAJLE_01548 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
MKELAJLE_01549 1.1e-12 S Uncharacterized protein YkpC
MKELAJLE_01550 7.7e-183 mreB D Rod-share determining protein MreBH
MKELAJLE_01551 1.5e-43 abrB K of stationary sporulation gene expression
MKELAJLE_01552 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
MKELAJLE_01553 1.6e-162 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
MKELAJLE_01554 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
MKELAJLE_01555 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MKELAJLE_01556 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MKELAJLE_01557 8.2e-31 ykzG S Belongs to the UPF0356 family
MKELAJLE_01558 1.4e-147 ykrA S hydrolases of the HAD superfamily
MKELAJLE_01559 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MKELAJLE_01561 2e-115 recN L Putative cell-wall binding lipoprotein
MKELAJLE_01562 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MKELAJLE_01563 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MKELAJLE_01564 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MKELAJLE_01565 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MKELAJLE_01566 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
MKELAJLE_01567 3.5e-277 speA 4.1.1.19 E Arginine
MKELAJLE_01568 1.6e-42 yktA S Belongs to the UPF0223 family
MKELAJLE_01569 7.1e-118 yktB S Belongs to the UPF0637 family
MKELAJLE_01570 7.1e-26 ykzI
MKELAJLE_01571 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
MKELAJLE_01572 6.9e-78 ykzC S Acetyltransferase (GNAT) family
MKELAJLE_01573 6.5e-173 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MKELAJLE_01574 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
MKELAJLE_01575 0.0 ylaA
MKELAJLE_01576 2.7e-42 ylaB
MKELAJLE_01577 2.7e-91 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
MKELAJLE_01578 1.2e-11 sigC S Putative zinc-finger
MKELAJLE_01579 1.8e-38 ylaE
MKELAJLE_01580 8.2e-22 S Family of unknown function (DUF5325)
MKELAJLE_01581 0.0 typA T GTP-binding protein TypA
MKELAJLE_01582 4.2e-47 ylaH S YlaH-like protein
MKELAJLE_01583 2.5e-32 ylaI S protein conserved in bacteria
MKELAJLE_01584 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MKELAJLE_01585 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
MKELAJLE_01586 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MKELAJLE_01587 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
MKELAJLE_01588 8.7e-44 ylaN S Belongs to the UPF0358 family
MKELAJLE_01589 4.5e-214 ftsW D Belongs to the SEDS family
MKELAJLE_01590 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MKELAJLE_01591 2.6e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MKELAJLE_01592 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MKELAJLE_01593 6.2e-191 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MKELAJLE_01594 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MKELAJLE_01595 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MKELAJLE_01596 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MKELAJLE_01597 3e-167 ctaG S cytochrome c oxidase
MKELAJLE_01598 7e-62 ylbA S YugN-like family
MKELAJLE_01599 2.6e-74 ylbB T COG0517 FOG CBS domain
MKELAJLE_01600 3e-201 ylbC S protein with SCP PR1 domains
MKELAJLE_01601 4.1e-63 ylbD S Putative coat protein
MKELAJLE_01602 6.7e-37 ylbE S YlbE-like protein
MKELAJLE_01603 1.8e-75 ylbF S Belongs to the UPF0342 family
MKELAJLE_01604 7.5e-39 ylbG S UPF0298 protein
MKELAJLE_01605 1.9e-98 rsmD 2.1.1.171 L Methyltransferase
MKELAJLE_01606 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MKELAJLE_01607 3.8e-221 ylbJ S Sporulation integral membrane protein YlbJ
MKELAJLE_01608 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
MKELAJLE_01609 6.8e-187 ylbL T Belongs to the peptidase S16 family
MKELAJLE_01610 2.8e-235 ylbM S Belongs to the UPF0348 family
MKELAJLE_01612 1.3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
MKELAJLE_01613 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MKELAJLE_01614 6.8e-75 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MKELAJLE_01615 4e-89 ylbP K n-acetyltransferase
MKELAJLE_01616 7.3e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MKELAJLE_01617 2.9e-309 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MKELAJLE_01618 2.9e-78 mraZ K Belongs to the MraZ family
MKELAJLE_01619 6.6e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MKELAJLE_01620 3.7e-44 ftsL D Essential cell division protein
MKELAJLE_01621 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
MKELAJLE_01622 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
MKELAJLE_01623 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MKELAJLE_01624 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MKELAJLE_01625 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MKELAJLE_01626 5.7e-186 spoVE D Belongs to the SEDS family
MKELAJLE_01627 2.3e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MKELAJLE_01628 5.3e-167 murB 1.3.1.98 M cell wall formation
MKELAJLE_01629 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MKELAJLE_01630 2.4e-103 ylxW S protein conserved in bacteria
MKELAJLE_01631 1e-102 ylxX S protein conserved in bacteria
MKELAJLE_01632 6.2e-58 sbp S small basic protein
MKELAJLE_01633 2.4e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MKELAJLE_01634 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MKELAJLE_01635 0.0 bpr O COG1404 Subtilisin-like serine proteases
MKELAJLE_01636 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MKELAJLE_01637 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKELAJLE_01638 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKELAJLE_01639 1.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MKELAJLE_01640 1.3e-256 argE 3.5.1.16 E Acetylornithine deacetylase
MKELAJLE_01641 2.4e-37 ylmC S sporulation protein
MKELAJLE_01642 1.1e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
MKELAJLE_01643 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MKELAJLE_01644 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MKELAJLE_01645 1.3e-39 yggT S membrane
MKELAJLE_01646 6.7e-139 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
MKELAJLE_01647 2.6e-67 divIVA D Cell division initiation protein
MKELAJLE_01648 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MKELAJLE_01649 1.3e-63 dksA T COG1734 DnaK suppressor protein
MKELAJLE_01650 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MKELAJLE_01651 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MKELAJLE_01652 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MKELAJLE_01653 9e-232 pyrP F Xanthine uracil
MKELAJLE_01654 1.4e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MKELAJLE_01655 1.7e-251 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MKELAJLE_01656 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MKELAJLE_01657 0.0 carB 6.3.5.5 F Belongs to the CarB family
MKELAJLE_01658 4.8e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MKELAJLE_01659 2.9e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MKELAJLE_01660 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MKELAJLE_01661 2.9e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MKELAJLE_01663 3.5e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
MKELAJLE_01664 1.1e-179 cysP P phosphate transporter
MKELAJLE_01665 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
MKELAJLE_01666 7.3e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
MKELAJLE_01667 2.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
MKELAJLE_01668 2e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
MKELAJLE_01669 4.3e-83 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
MKELAJLE_01670 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
MKELAJLE_01671 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
MKELAJLE_01672 2.4e-156 yloC S stress-induced protein
MKELAJLE_01673 1.5e-40 ylzA S Belongs to the UPF0296 family
MKELAJLE_01674 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MKELAJLE_01675 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MKELAJLE_01676 8.8e-226 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MKELAJLE_01677 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MKELAJLE_01678 6e-85 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MKELAJLE_01679 3.8e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MKELAJLE_01680 2.9e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MKELAJLE_01681 4.8e-207 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MKELAJLE_01682 2.4e-141 stp 3.1.3.16 T phosphatase
MKELAJLE_01683 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
MKELAJLE_01684 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MKELAJLE_01685 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MKELAJLE_01686 3.1e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
MKELAJLE_01687 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MKELAJLE_01688 5.5e-59 asp S protein conserved in bacteria
MKELAJLE_01689 2.7e-302 yloV S kinase related to dihydroxyacetone kinase
MKELAJLE_01690 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
MKELAJLE_01691 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
MKELAJLE_01692 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MKELAJLE_01693 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MKELAJLE_01694 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MKELAJLE_01695 9.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MKELAJLE_01696 6.1e-129 IQ reductase
MKELAJLE_01697 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MKELAJLE_01698 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MKELAJLE_01699 0.0 smc D Required for chromosome condensation and partitioning
MKELAJLE_01700 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MKELAJLE_01701 2.9e-87
MKELAJLE_01702 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MKELAJLE_01703 6e-236 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MKELAJLE_01704 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MKELAJLE_01705 1.2e-36 ylqC S Belongs to the UPF0109 family
MKELAJLE_01706 1.3e-61 ylqD S YlqD protein
MKELAJLE_01707 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MKELAJLE_01708 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MKELAJLE_01709 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MKELAJLE_01710 4.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MKELAJLE_01711 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MKELAJLE_01712 8.5e-291 ylqG
MKELAJLE_01713 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
MKELAJLE_01714 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MKELAJLE_01715 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MKELAJLE_01716 1.7e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
MKELAJLE_01717 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MKELAJLE_01718 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MKELAJLE_01719 2.5e-169 xerC L tyrosine recombinase XerC
MKELAJLE_01720 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MKELAJLE_01721 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MKELAJLE_01722 1.6e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MKELAJLE_01723 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MKELAJLE_01724 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
MKELAJLE_01725 1.9e-31 fliE N Flagellar hook-basal body
MKELAJLE_01726 2.4e-255 fliF N The M ring may be actively involved in energy transduction
MKELAJLE_01727 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MKELAJLE_01728 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
MKELAJLE_01729 2.5e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MKELAJLE_01730 1.5e-69 fliJ N Flagellar biosynthesis chaperone
MKELAJLE_01731 7.7e-37 ylxF S MgtE intracellular N domain
MKELAJLE_01732 1.2e-221 fliK N Flagellar hook-length control protein
MKELAJLE_01733 1.7e-72 flgD N Flagellar basal body rod modification protein
MKELAJLE_01734 8.2e-140 flgG N Flagellar basal body rod
MKELAJLE_01735 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
MKELAJLE_01736 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MKELAJLE_01737 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MKELAJLE_01738 1.6e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
MKELAJLE_01739 9.3e-97 fliZ N Flagellar biosynthesis protein, FliO
MKELAJLE_01740 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
MKELAJLE_01741 2.2e-36 fliQ N Role in flagellar biosynthesis
MKELAJLE_01742 3.6e-132 fliR N Flagellar biosynthetic protein FliR
MKELAJLE_01743 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MKELAJLE_01744 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MKELAJLE_01745 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
MKELAJLE_01746 7.5e-158 flhG D Belongs to the ParA family
MKELAJLE_01747 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MKELAJLE_01748 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
MKELAJLE_01749 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
MKELAJLE_01750 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MKELAJLE_01751 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MKELAJLE_01752 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKELAJLE_01753 4.3e-78 ylxL
MKELAJLE_01754 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
MKELAJLE_01755 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MKELAJLE_01756 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MKELAJLE_01757 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MKELAJLE_01758 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MKELAJLE_01759 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
MKELAJLE_01760 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MKELAJLE_01761 7.7e-233 rasP M zinc metalloprotease
MKELAJLE_01762 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MKELAJLE_01763 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MKELAJLE_01764 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
MKELAJLE_01765 1.1e-203 nusA K Participates in both transcription termination and antitermination
MKELAJLE_01766 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
MKELAJLE_01767 3.1e-47 ylxQ J ribosomal protein
MKELAJLE_01768 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MKELAJLE_01769 3e-44 ylxP S protein conserved in bacteria
MKELAJLE_01770 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MKELAJLE_01771 1.3e-173 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MKELAJLE_01772 6.1e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MKELAJLE_01773 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MKELAJLE_01774 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MKELAJLE_01775 4.2e-183 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
MKELAJLE_01776 4.4e-233 pepR S Belongs to the peptidase M16 family
MKELAJLE_01777 2.6e-42 ymxH S YlmC YmxH family
MKELAJLE_01778 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
MKELAJLE_01779 4.3e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MKELAJLE_01780 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MKELAJLE_01781 5.9e-222 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
MKELAJLE_01782 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MKELAJLE_01783 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MKELAJLE_01784 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
MKELAJLE_01785 4.4e-32 S YlzJ-like protein
MKELAJLE_01786 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MKELAJLE_01787 1.4e-133 ymfC K Transcriptional regulator
MKELAJLE_01788 1.5e-206 ymfD EGP Major facilitator Superfamily
MKELAJLE_01789 2.6e-236 ymfF S Peptidase M16
MKELAJLE_01790 1.4e-242 ymfH S zinc protease
MKELAJLE_01791 9.2e-130 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
MKELAJLE_01792 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
MKELAJLE_01793 2.7e-143 ymfK S Protein of unknown function (DUF3388)
MKELAJLE_01794 1.9e-124 ymfM S protein conserved in bacteria
MKELAJLE_01795 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MKELAJLE_01796 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
MKELAJLE_01797 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MKELAJLE_01798 1e-215 pbpX V Beta-lactamase
MKELAJLE_01799 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
MKELAJLE_01800 1.9e-152 ymdB S protein conserved in bacteria
MKELAJLE_01801 1.2e-36 spoVS S Stage V sporulation protein S
MKELAJLE_01802 2.7e-199 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
MKELAJLE_01803 6.5e-218 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MKELAJLE_01804 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MKELAJLE_01805 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
MKELAJLE_01806 2.2e-88 cotE S Spore coat protein
MKELAJLE_01807 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MKELAJLE_01808 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MKELAJLE_01809 2.3e-70 S Regulatory protein YrvL
MKELAJLE_01811 1.2e-97 ymcC S Membrane
MKELAJLE_01812 4.4e-109 pksA K Transcriptional regulator
MKELAJLE_01813 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
MKELAJLE_01814 2.6e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MKELAJLE_01815 2.4e-186 pksD Q Acyl transferase domain
MKELAJLE_01816 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MKELAJLE_01817 1.4e-37 acpK IQ Phosphopantetheine attachment site
MKELAJLE_01818 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MKELAJLE_01819 1.3e-245 pksG 2.3.3.10 I synthase
MKELAJLE_01820 2.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
MKELAJLE_01821 2.7e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
MKELAJLE_01822 0.0 rhiB IQ polyketide synthase
MKELAJLE_01823 0.0 pfaA Q Polyketide synthase of type I
MKELAJLE_01824 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
MKELAJLE_01825 0.0 dhbF IQ polyketide synthase
MKELAJLE_01826 0.0 pks13 HQ Beta-ketoacyl synthase
MKELAJLE_01827 2.5e-233 cypA C Cytochrome P450
MKELAJLE_01828 1.2e-61 ymzB
MKELAJLE_01829 6.6e-164 ymaE S Metallo-beta-lactamase superfamily
MKELAJLE_01830 4.6e-252 aprX O Belongs to the peptidase S8 family
MKELAJLE_01831 2.1e-126 ymaC S Replication protein
MKELAJLE_01832 5.4e-80 ymaD O redox protein, regulator of disulfide bond formation
MKELAJLE_01833 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
MKELAJLE_01834 4.9e-51 ebrA P Small Multidrug Resistance protein
MKELAJLE_01836 2.1e-46 ymaF S YmaF family
MKELAJLE_01837 9.3e-175 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MKELAJLE_01838 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MKELAJLE_01839 6.3e-23
MKELAJLE_01840 4.5e-22 ymzA
MKELAJLE_01841 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
MKELAJLE_01842 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKELAJLE_01843 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKELAJLE_01844 2e-109 ymaB
MKELAJLE_01845 8e-116 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MKELAJLE_01846 1.7e-176 spoVK O stage V sporulation protein K
MKELAJLE_01847 5.5e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MKELAJLE_01848 3.3e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MKELAJLE_01849 1.1e-68 glnR K transcriptional
MKELAJLE_01850 7e-261 glnA 6.3.1.2 E glutamine synthetase
MKELAJLE_01851 5e-10
MKELAJLE_01852 2.5e-32
MKELAJLE_01853 5.8e-39
MKELAJLE_01854 6.8e-80 G regulation of fungal-type cell wall biogenesis
MKELAJLE_01855 4.9e-145 ynaC
MKELAJLE_01856 2e-99 ynaD J Acetyltransferase (GNAT) domain
MKELAJLE_01857 1.9e-123 ynaE S Domain of unknown function (DUF3885)
MKELAJLE_01858 6.4e-60 ynaF
MKELAJLE_01861 1.1e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
MKELAJLE_01862 2.7e-255 xynT G MFS/sugar transport protein
MKELAJLE_01863 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
MKELAJLE_01864 1e-215 xylR GK ROK family
MKELAJLE_01865 4e-264 xylA 5.3.1.5 G Belongs to the xylose isomerase family
MKELAJLE_01866 6e-293 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
MKELAJLE_01867 1.4e-113 yokF 3.1.31.1 L RNA catabolic process
MKELAJLE_01868 3.5e-247 iolT EGP Major facilitator Superfamily
MKELAJLE_01869 2.7e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MKELAJLE_01870 6.3e-84 yncE S Protein of unknown function (DUF2691)
MKELAJLE_01871 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
MKELAJLE_01872 5.2e-15
MKELAJLE_01875 1.2e-165 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MKELAJLE_01877 1.3e-134 S Domain of unknown function, YrpD
MKELAJLE_01880 7.9e-25 tatA U protein secretion
MKELAJLE_01881 1.8e-71
MKELAJLE_01882 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
MKELAJLE_01885 5.7e-286 gerAA EG Spore germination protein
MKELAJLE_01886 4.5e-197 gerAB U Spore germination
MKELAJLE_01887 4.2e-220 gerLC S Spore germination protein
MKELAJLE_01888 7.7e-154 yndG S DoxX-like family
MKELAJLE_01889 2.6e-117 yndH S Domain of unknown function (DUF4166)
MKELAJLE_01890 0.0 yndJ S YndJ-like protein
MKELAJLE_01892 8.6e-139 yndL S Replication protein
MKELAJLE_01893 5.8e-74 yndM S Protein of unknown function (DUF2512)
MKELAJLE_01894 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
MKELAJLE_01896 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MKELAJLE_01897 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
MKELAJLE_01898 9.2e-113 yneB L resolvase
MKELAJLE_01899 1.3e-32 ynzC S UPF0291 protein
MKELAJLE_01900 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MKELAJLE_01901 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
MKELAJLE_01902 1.8e-28 yneF S UPF0154 protein
MKELAJLE_01903 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
MKELAJLE_01904 7.1e-127 ccdA O cytochrome c biogenesis protein
MKELAJLE_01905 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
MKELAJLE_01906 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
MKELAJLE_01907 4.2e-74 yneK S Protein of unknown function (DUF2621)
MKELAJLE_01908 4.1e-65 hspX O Spore coat protein
MKELAJLE_01909 3.9e-19 sspP S Belongs to the SspP family
MKELAJLE_01910 2.2e-14 sspO S Belongs to the SspO family
MKELAJLE_01911 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MKELAJLE_01912 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MKELAJLE_01914 3.1e-08 sspN S Small acid-soluble spore protein N family
MKELAJLE_01915 3.9e-35 tlp S Belongs to the Tlp family
MKELAJLE_01916 1.2e-73 yneP S Thioesterase-like superfamily
MKELAJLE_01917 1.3e-53 yneQ
MKELAJLE_01918 4.1e-49 yneR S Belongs to the HesB IscA family
MKELAJLE_01919 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MKELAJLE_01920 6.6e-69 yccU S CoA-binding protein
MKELAJLE_01921 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MKELAJLE_01922 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MKELAJLE_01923 2.3e-12
MKELAJLE_01924 1.3e-57 ynfC
MKELAJLE_01925 8.2e-252 agcS E Sodium alanine symporter
MKELAJLE_01926 2.4e-297 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
MKELAJLE_01928 3.7e-251 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
MKELAJLE_01929 4.4e-299 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
MKELAJLE_01930 2.4e-80 yngA S membrane
MKELAJLE_01931 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MKELAJLE_01932 5.5e-104 yngC S membrane-associated protein
MKELAJLE_01933 1.9e-233 nrnB S phosphohydrolase (DHH superfamily)
MKELAJLE_01934 6.3e-290 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MKELAJLE_01935 2.2e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
MKELAJLE_01936 8e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
MKELAJLE_01937 6e-32 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
MKELAJLE_01938 3e-251 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
MKELAJLE_01939 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MKELAJLE_01940 4.4e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
MKELAJLE_01941 1.8e-31 S Family of unknown function (DUF5367)
MKELAJLE_01943 1.3e-306 yngK T Glycosyl hydrolase-like 10
MKELAJLE_01944 2.8e-64 yngL S Protein of unknown function (DUF1360)
MKELAJLE_01945 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
MKELAJLE_01946 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKELAJLE_01947 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKELAJLE_01948 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKELAJLE_01949 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKELAJLE_01950 4.3e-275 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
MKELAJLE_01951 6e-193 yoxA 5.1.3.3 G Aldose 1-epimerase
MKELAJLE_01952 2.3e-246 yoeA V MATE efflux family protein
MKELAJLE_01953 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
MKELAJLE_01955 2.2e-96 L Integrase
MKELAJLE_01956 3e-34 yoeD G Helix-turn-helix domain
MKELAJLE_01957 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
MKELAJLE_01958 2.5e-158 gltR1 K Transcriptional regulator
MKELAJLE_01959 5e-187 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MKELAJLE_01960 2.7e-293 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MKELAJLE_01961 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
MKELAJLE_01962 7.8e-155 gltC K Transcriptional regulator
MKELAJLE_01963 4.1e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MKELAJLE_01964 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MKELAJLE_01965 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
MKELAJLE_01966 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MKELAJLE_01967 3e-42 yoxC S Bacterial protein of unknown function (DUF948)
MKELAJLE_01968 3.1e-144 yoxB
MKELAJLE_01969 7.5e-97 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MKELAJLE_01970 6.2e-235 yoaB EGP Major facilitator Superfamily
MKELAJLE_01971 1e-284 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
MKELAJLE_01972 1.7e-190 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKELAJLE_01973 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MKELAJLE_01974 1.9e-33 yoaF
MKELAJLE_01975 2.2e-08 ywlA S Uncharacterised protein family (UPF0715)
MKELAJLE_01976 7e-14
MKELAJLE_01977 1.5e-38 S Protein of unknown function (DUF4025)
MKELAJLE_01978 1.7e-187 mcpU NT methyl-accepting chemotaxis protein
MKELAJLE_01979 8.7e-281 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
MKELAJLE_01980 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
MKELAJLE_01981 2.3e-111 yoaK S Membrane
MKELAJLE_01982 2.3e-198 pelB 4.2.2.10, 4.2.2.2 G Amb_all
MKELAJLE_01983 1.1e-132 yoqW S Belongs to the SOS response-associated peptidase family
MKELAJLE_01985 3.8e-234 oxdC 4.1.1.2 G Oxalate decarboxylase
MKELAJLE_01987 1.5e-146 yoaP 3.1.3.18 K YoaP-like
MKELAJLE_01988 1.2e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
MKELAJLE_01989 4.1e-89
MKELAJLE_01990 2.4e-172 yoaR V vancomycin resistance protein
MKELAJLE_01991 4.3e-75 yoaS S Protein of unknown function (DUF2975)
MKELAJLE_01992 4.2e-37 yozG K Transcriptional regulator
MKELAJLE_01993 1.1e-149 yoaT S Protein of unknown function (DUF817)
MKELAJLE_01994 8.6e-159 yoaU K LysR substrate binding domain
MKELAJLE_01995 6e-160 yijE EG EamA-like transporter family
MKELAJLE_01996 3.7e-78 yoaW
MKELAJLE_01997 1.1e-118 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
MKELAJLE_01998 2.3e-170 bla 3.5.2.6 V beta-lactamase
MKELAJLE_02002 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
MKELAJLE_02003 1.8e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
MKELAJLE_02004 1.4e-37 S TM2 domain
MKELAJLE_02005 5.7e-58 K Helix-turn-helix
MKELAJLE_02007 1.6e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
MKELAJLE_02008 6.6e-127 yoqW S Belongs to the SOS response-associated peptidase family
MKELAJLE_02009 1.8e-178 yobF
MKELAJLE_02014 1.7e-207 S aspartate phosphatase
MKELAJLE_02016 1.2e-123 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MKELAJLE_02017 1.4e-59 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MKELAJLE_02018 2.6e-38 S YolD-like protein
MKELAJLE_02019 1.2e-49
MKELAJLE_02020 0.0 K Psort location Cytoplasmic, score
MKELAJLE_02021 2.7e-157 yobJ
MKELAJLE_02022 3e-86 S SMI1-KNR4 cell-wall
MKELAJLE_02023 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MKELAJLE_02024 7.9e-105 yokH G SMI1 / KNR4 family
MKELAJLE_02025 9.5e-280 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
MKELAJLE_02026 0.0 yobO M Pectate lyase superfamily protein
MKELAJLE_02027 9.9e-55 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
MKELAJLE_02028 1e-136 yobQ K helix_turn_helix, arabinose operon control protein
MKELAJLE_02029 2.5e-143 yobR 2.3.1.1 J FR47-like protein
MKELAJLE_02030 3e-99 yobS K Transcriptional regulator
MKELAJLE_02031 4.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
MKELAJLE_02032 1.5e-88 yobU K Bacterial transcription activator, effector binding domain
MKELAJLE_02033 9e-178 yobV K WYL domain
MKELAJLE_02034 2.5e-95 yobW
MKELAJLE_02035 1e-51 czrA K transcriptional
MKELAJLE_02036 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MKELAJLE_02037 1.5e-92 yozB S membrane
MKELAJLE_02038 2.2e-145
MKELAJLE_02039 1.9e-94 yocC
MKELAJLE_02040 6.9e-189 yocD 3.4.17.13 V peptidase S66
MKELAJLE_02041 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
MKELAJLE_02042 3.2e-198 desK 2.7.13.3 T Histidine kinase
MKELAJLE_02043 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKELAJLE_02044 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
MKELAJLE_02045 0.0 recQ 3.6.4.12 L DNA helicase
MKELAJLE_02046 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MKELAJLE_02047 3.3e-83 dksA T general stress protein
MKELAJLE_02048 6.4e-54 yocL
MKELAJLE_02049 6.6e-34
MKELAJLE_02050 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
MKELAJLE_02051 1.1e-40 yozN
MKELAJLE_02052 1.9e-36 yocN
MKELAJLE_02053 4.2e-56 yozO S Bacterial PH domain
MKELAJLE_02054 2.7e-31 yozC
MKELAJLE_02055 5.8e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
MKELAJLE_02056 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
MKELAJLE_02057 5.4e-166 sodA 1.15.1.1 P Superoxide dismutase
MKELAJLE_02058 3.4e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MKELAJLE_02059 5.1e-168 yocS S -transporter
MKELAJLE_02060 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MKELAJLE_02061 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MKELAJLE_02062 0.0 yojO P Von Willebrand factor
MKELAJLE_02063 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
MKELAJLE_02064 1e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MKELAJLE_02065 1.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MKELAJLE_02066 1.8e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
MKELAJLE_02067 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MKELAJLE_02069 4.2e-245 norM V Multidrug efflux pump
MKELAJLE_02070 8.4e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MKELAJLE_02071 2.1e-125 yojG S deacetylase
MKELAJLE_02072 2.2e-60 yojF S Protein of unknown function (DUF1806)
MKELAJLE_02073 1.5e-43
MKELAJLE_02074 3.5e-163 rarD S -transporter
MKELAJLE_02075 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
MKELAJLE_02076 3.4e-09
MKELAJLE_02077 8.2e-209 gntP EG COG2610 H gluconate symporter and related permeases
MKELAJLE_02078 3.8e-66 yodA S tautomerase
MKELAJLE_02079 1.7e-57 yodB K transcriptional
MKELAJLE_02080 4.8e-108 yodC C nitroreductase
MKELAJLE_02081 3.8e-113 mhqD S Carboxylesterase
MKELAJLE_02082 5.8e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
MKELAJLE_02083 6.2e-28 S Protein of unknown function (DUF3311)
MKELAJLE_02084 4.2e-270 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MKELAJLE_02085 1.9e-253 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
MKELAJLE_02086 1.7e-128 yodH Q Methyltransferase
MKELAJLE_02087 5.2e-24 yodI
MKELAJLE_02088 2.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
MKELAJLE_02089 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
MKELAJLE_02090 5.3e-09
MKELAJLE_02091 3.6e-54 yodL S YodL-like
MKELAJLE_02092 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
MKELAJLE_02093 2.8e-24 yozD S YozD-like protein
MKELAJLE_02095 1.4e-124 yodN
MKELAJLE_02096 1.4e-36 yozE S Belongs to the UPF0346 family
MKELAJLE_02097 2.9e-47 yokU S YokU-like protein, putative antitoxin
MKELAJLE_02098 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
MKELAJLE_02099 2.5e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
MKELAJLE_02100 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
MKELAJLE_02101 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MKELAJLE_02102 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MKELAJLE_02103 1.6e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MKELAJLE_02106 2.9e-145 yiiD K acetyltransferase
MKELAJLE_02107 1e-256 cgeD M maturation of the outermost layer of the spore
MKELAJLE_02108 3.5e-38 cgeC
MKELAJLE_02109 1.2e-65 cgeA
MKELAJLE_02110 3.3e-188 cgeB S Spore maturation protein
MKELAJLE_02111 3.6e-213 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
MKELAJLE_02112 2.5e-63 4.2.1.115 GM Polysaccharide biosynthesis protein
MKELAJLE_02114 3.6e-108 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MKELAJLE_02115 1.4e-10 K Cro/C1-type HTH DNA-binding domain
MKELAJLE_02123 1.9e-168 S Calcineurin-like phosphoesterase
MKELAJLE_02124 2.5e-30 sspB S spore protein
MKELAJLE_02129 8.9e-83 yosT L Bacterial transcription activator, effector binding domain
MKELAJLE_02130 2.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
MKELAJLE_02131 6.1e-38 O Glutaredoxin
MKELAJLE_02132 2.8e-66 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKELAJLE_02133 3.3e-97 L HNH endonuclease
MKELAJLE_02134 1e-107 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKELAJLE_02135 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKELAJLE_02136 2.3e-117 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKELAJLE_02137 5.1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
MKELAJLE_02154 1.5e-255 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
MKELAJLE_02156 1.2e-96 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
MKELAJLE_02157 5.9e-88 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
MKELAJLE_02162 9.9e-115 DR0488 S protein conserved in bacteria
MKELAJLE_02163 0.0 2.7.7.7 L DNA polymerase
MKELAJLE_02164 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MKELAJLE_02165 1.2e-224 L DNA primase activity
MKELAJLE_02166 3.6e-285 3.6.4.12 J DnaB-like helicase C terminal domain
MKELAJLE_02167 1.4e-86
MKELAJLE_02168 7.6e-180 L AAA domain
MKELAJLE_02169 1.3e-170
MKELAJLE_02174 0.0 M Parallel beta-helix repeats
MKELAJLE_02175 7.7e-149 S Pfam:DUF867
MKELAJLE_02178 1e-130 yoqW S Belongs to the SOS response-associated peptidase family
MKELAJLE_02179 2.4e-155 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
MKELAJLE_02180 2.3e-77
MKELAJLE_02187 1e-44
MKELAJLE_02189 1.5e-97 S Protein of unknown function (DUF1273)
MKELAJLE_02191 3e-78 yoqH M LysM domain
MKELAJLE_02194 8.8e-12 S Protein of unknown function (DUF2815)
MKELAJLE_02195 6.2e-137 kilA S Phage regulatory protein Rha (Phage_pRha)
MKELAJLE_02206 1.1e-33 K Transcriptional regulator
MKELAJLE_02207 2.1e-177
MKELAJLE_02208 6e-263 S DNA-sulfur modification-associated
MKELAJLE_02209 6.8e-198 L Belongs to the 'phage' integrase family
MKELAJLE_02214 6.6e-106
MKELAJLE_02216 1.2e-86
MKELAJLE_02217 1.1e-96 S Super-infection exclusion protein B
MKELAJLE_02222 1.1e-07 ywlA S Uncharacterised protein family (UPF0715)
MKELAJLE_02223 3.8e-259
MKELAJLE_02224 4.6e-35 K Cro/C1-type HTH DNA-binding domain
MKELAJLE_02225 1.4e-256
MKELAJLE_02227 5.9e-238
MKELAJLE_02229 4e-17
MKELAJLE_02230 5.7e-55 bldD K domain, Protein
MKELAJLE_02233 0.0
MKELAJLE_02234 1.8e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MKELAJLE_02236 2.6e-230
MKELAJLE_02239 1.8e-175
MKELAJLE_02240 0.0 gp17a S Terminase-like family
MKELAJLE_02241 6.3e-282
MKELAJLE_02242 2.1e-266
MKELAJLE_02243 1.6e-94
MKELAJLE_02244 5.7e-186
MKELAJLE_02245 5.1e-81
MKELAJLE_02246 1.1e-68
MKELAJLE_02248 1.4e-121
MKELAJLE_02249 2.6e-91
MKELAJLE_02250 8.1e-131
MKELAJLE_02251 1.6e-90
MKELAJLE_02254 1e-57
MKELAJLE_02255 1.1e-172
MKELAJLE_02256 8.1e-07
MKELAJLE_02257 2.5e-10 xkdX
MKELAJLE_02258 2.5e-86
MKELAJLE_02259 6.3e-70
MKELAJLE_02260 2.1e-193 xerH A Belongs to the 'phage' integrase family
MKELAJLE_02265 9.3e-116
MKELAJLE_02266 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MKELAJLE_02267 6.2e-145 S Phage tail protein
MKELAJLE_02268 0.0 S Pfam Transposase IS66
MKELAJLE_02269 6.4e-115
MKELAJLE_02270 0.0 G Exopolysaccharide biosynthesis protein
MKELAJLE_02271 6.5e-164
MKELAJLE_02273 1.6e-186 3.5.1.28 M Ami_2
MKELAJLE_02274 4.4e-32 bhlA S BhlA holin family
MKELAJLE_02275 5.5e-40 S SPP1 phage holin
MKELAJLE_02276 3.4e-74 O protein disulfide oxidoreductase activity
MKELAJLE_02277 4.1e-242 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MKELAJLE_02278 1.2e-70 CO cell redox homeostasis
MKELAJLE_02279 0.0 V Peptidase C39 family
MKELAJLE_02282 1.9e-239 S impB/mucB/samB family C-terminal domain
MKELAJLE_02283 5.8e-55 S YolD-like protein
MKELAJLE_02284 1.3e-37
MKELAJLE_02286 6.8e-09 S Domain of unknown function (DUF4879)
MKELAJLE_02288 2.8e-99 J Acetyltransferase (GNAT) domain
MKELAJLE_02289 3.2e-109 yokK S SMI1 / KNR4 family
MKELAJLE_02290 1.9e-94 yokJ S SMI1 / KNR4 family (SUKH-1)
MKELAJLE_02291 1.2e-302 UW nuclease activity
MKELAJLE_02292 6.7e-92 yokH G SMI1 / KNR4 family
MKELAJLE_02293 4.1e-203
MKELAJLE_02294 3.3e-113 yokF 3.1.31.1 L RNA catabolic process
MKELAJLE_02295 1.1e-83 S Bacterial PH domain
MKELAJLE_02296 8.4e-156 aacC 2.3.1.81 V aminoglycoside
MKELAJLE_02299 8.9e-95
MKELAJLE_02300 1.6e-107
MKELAJLE_02301 2.7e-307 yokA L Recombinase
MKELAJLE_02302 1.4e-96 4.2.1.115 GM Polysaccharide biosynthesis protein
MKELAJLE_02303 1.4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MKELAJLE_02304 7e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MKELAJLE_02305 1.6e-70 ypoP K transcriptional
MKELAJLE_02306 2.6e-223 mepA V MATE efflux family protein
MKELAJLE_02307 5.5e-29 ypmT S Uncharacterized ympT
MKELAJLE_02308 5e-99 ypmS S protein conserved in bacteria
MKELAJLE_02309 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
MKELAJLE_02310 3.2e-109 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MKELAJLE_02311 3.1e-40 ypmP S Protein of unknown function (DUF2535)
MKELAJLE_02312 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MKELAJLE_02313 1.6e-185 pspF K Transcriptional regulator
MKELAJLE_02314 4.2e-110 hlyIII S protein, Hemolysin III
MKELAJLE_02315 7.4e-112 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MKELAJLE_02316 7.9e-96 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MKELAJLE_02317 4.3e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MKELAJLE_02318 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
MKELAJLE_02319 7.8e-114 ypjP S YpjP-like protein
MKELAJLE_02320 1.3e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
MKELAJLE_02321 1.7e-75 yphP S Belongs to the UPF0403 family
MKELAJLE_02322 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
MKELAJLE_02323 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
MKELAJLE_02324 3.1e-110 ypgQ S phosphohydrolase
MKELAJLE_02325 2.3e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
MKELAJLE_02326 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MKELAJLE_02327 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
MKELAJLE_02328 7.9e-31 cspD K Cold-shock protein
MKELAJLE_02329 3.8e-16 degR
MKELAJLE_02330 8.1e-31 S Protein of unknown function (DUF2564)
MKELAJLE_02331 3e-29 ypeQ S Zinc-finger
MKELAJLE_02332 8.9e-127 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
MKELAJLE_02333 5.4e-107 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MKELAJLE_02334 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
MKELAJLE_02336 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
MKELAJLE_02337 2e-07
MKELAJLE_02338 1e-38 ypbS S Protein of unknown function (DUF2533)
MKELAJLE_02339 0.0 ypbR S Dynamin family
MKELAJLE_02340 5.1e-87 ypbQ S protein conserved in bacteria
MKELAJLE_02341 4.4e-208 bcsA Q Naringenin-chalcone synthase
MKELAJLE_02342 1.6e-228 pbuX F xanthine
MKELAJLE_02343 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MKELAJLE_02344 4.2e-294 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MKELAJLE_02345 5e-171 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
MKELAJLE_02346 7e-104 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
MKELAJLE_02347 2.9e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
MKELAJLE_02348 3.9e-187 ptxS K transcriptional
MKELAJLE_02349 1.7e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MKELAJLE_02350 7.1e-133 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKELAJLE_02351 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
MKELAJLE_02353 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MKELAJLE_02354 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MKELAJLE_02355 3.3e-92 ypsA S Belongs to the UPF0398 family
MKELAJLE_02356 1.3e-237 yprB L RNase_H superfamily
MKELAJLE_02357 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MKELAJLE_02358 1.9e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
MKELAJLE_02359 8.6e-72 hspX O Belongs to the small heat shock protein (HSP20) family
MKELAJLE_02360 1.2e-48 yppG S YppG-like protein
MKELAJLE_02362 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
MKELAJLE_02365 2.6e-188 yppC S Protein of unknown function (DUF2515)
MKELAJLE_02366 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MKELAJLE_02367 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
MKELAJLE_02368 4.7e-93 ypoC
MKELAJLE_02369 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MKELAJLE_02370 5.7e-129 dnaD L DNA replication protein DnaD
MKELAJLE_02371 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
MKELAJLE_02372 1.5e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
MKELAJLE_02373 3.4e-80 ypmB S protein conserved in bacteria
MKELAJLE_02374 6.7e-23 ypmA S Protein of unknown function (DUF4264)
MKELAJLE_02375 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MKELAJLE_02376 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MKELAJLE_02377 1.2e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MKELAJLE_02378 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MKELAJLE_02379 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MKELAJLE_02380 4.4e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MKELAJLE_02381 3.7e-210 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
MKELAJLE_02382 6.9e-130 bshB1 S proteins, LmbE homologs
MKELAJLE_02383 6.5e-72 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
MKELAJLE_02384 6.3e-148 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MKELAJLE_02385 3.1e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
MKELAJLE_02386 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
MKELAJLE_02387 6.1e-143 ypjB S sporulation protein
MKELAJLE_02388 4.4e-98 ypjA S membrane
MKELAJLE_02389 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
MKELAJLE_02390 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
MKELAJLE_02391 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
MKELAJLE_02392 8.5e-78 ypiF S Protein of unknown function (DUF2487)
MKELAJLE_02393 2.8e-99 ypiB S Belongs to the UPF0302 family
MKELAJLE_02394 4.1e-234 S COG0457 FOG TPR repeat
MKELAJLE_02395 8.9e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MKELAJLE_02396 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
MKELAJLE_02397 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MKELAJLE_02398 5.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MKELAJLE_02399 4e-231 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MKELAJLE_02400 6.5e-119 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
MKELAJLE_02401 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
MKELAJLE_02402 1.2e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MKELAJLE_02403 6.6e-295 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MKELAJLE_02404 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
MKELAJLE_02405 8.1e-207 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MKELAJLE_02406 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MKELAJLE_02407 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
MKELAJLE_02408 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MKELAJLE_02409 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MKELAJLE_02410 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MKELAJLE_02411 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
MKELAJLE_02412 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MKELAJLE_02413 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
MKELAJLE_02414 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MKELAJLE_02415 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MKELAJLE_02416 5.4e-138 yphF
MKELAJLE_02417 1.6e-18 yphE S Protein of unknown function (DUF2768)
MKELAJLE_02418 2.3e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MKELAJLE_02419 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MKELAJLE_02420 1.6e-28 ypzH
MKELAJLE_02421 2.5e-161 seaA S YIEGIA protein
MKELAJLE_02422 1.3e-102 yphA
MKELAJLE_02423 1e-07 S YpzI-like protein
MKELAJLE_02424 4.1e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MKELAJLE_02425 4.3e-206 rpsA 1.17.7.4 J Ribosomal protein S1
MKELAJLE_02426 1.9e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MKELAJLE_02427 1.8e-23 S Family of unknown function (DUF5359)
MKELAJLE_02428 9.2e-113 ypfA M Flagellar protein YcgR
MKELAJLE_02429 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
MKELAJLE_02430 4.7e-155 sleB 3.5.1.28 M Spore cortex-lytic enzyme
MKELAJLE_02431 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
MKELAJLE_02432 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
MKELAJLE_02433 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
MKELAJLE_02434 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MKELAJLE_02435 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
MKELAJLE_02436 2.8e-81 ypbF S Protein of unknown function (DUF2663)
MKELAJLE_02437 4.6e-81 ypbE M Lysin motif
MKELAJLE_02438 2.2e-100 ypbD S metal-dependent membrane protease
MKELAJLE_02439 3.2e-286 recQ 3.6.4.12 L DNA helicase
MKELAJLE_02440 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
MKELAJLE_02441 4.7e-41 fer C Ferredoxin
MKELAJLE_02442 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MKELAJLE_02443 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKELAJLE_02444 9e-136 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MKELAJLE_02445 6.8e-201 rsiX
MKELAJLE_02446 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
MKELAJLE_02447 0.0 resE 2.7.13.3 T Histidine kinase
MKELAJLE_02448 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKELAJLE_02449 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MKELAJLE_02450 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
MKELAJLE_02451 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MKELAJLE_02452 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MKELAJLE_02453 1.9e-87 spmB S Spore maturation protein
MKELAJLE_02454 3.5e-103 spmA S Spore maturation protein
MKELAJLE_02455 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
MKELAJLE_02456 4e-98 ypuI S Protein of unknown function (DUF3907)
MKELAJLE_02457 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MKELAJLE_02458 4.5e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MKELAJLE_02459 4.5e-94 ypuF S Domain of unknown function (DUF309)
MKELAJLE_02460 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKELAJLE_02461 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MKELAJLE_02462 9.8e-230 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MKELAJLE_02463 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
MKELAJLE_02464 1.3e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MKELAJLE_02465 6e-55 ypuD
MKELAJLE_02466 5.2e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MKELAJLE_02467 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
MKELAJLE_02468 1.5e-17 S SNARE associated Golgi protein
MKELAJLE_02471 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MKELAJLE_02472 1.3e-149 ypuA S Secreted protein
MKELAJLE_02473 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MKELAJLE_02474 1.4e-273 spoVAF EG Stage V sporulation protein AF
MKELAJLE_02475 1.4e-110 spoVAEA S stage V sporulation protein
MKELAJLE_02476 2.2e-57 spoVAEB S stage V sporulation protein
MKELAJLE_02477 9e-192 spoVAD I Stage V sporulation protein AD
MKELAJLE_02478 2.3e-78 spoVAC S stage V sporulation protein AC
MKELAJLE_02479 1e-67 spoVAB S Stage V sporulation protein AB
MKELAJLE_02480 7.4e-112 spoVAA S Stage V sporulation protein AA
MKELAJLE_02481 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKELAJLE_02482 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MKELAJLE_02483 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
MKELAJLE_02484 2.8e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
MKELAJLE_02485 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MKELAJLE_02486 1.2e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
MKELAJLE_02487 2.6e-166 xerD L recombinase XerD
MKELAJLE_02488 3.7e-37 S Protein of unknown function (DUF4227)
MKELAJLE_02489 2.4e-80 fur P Belongs to the Fur family
MKELAJLE_02490 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MKELAJLE_02491 2e-32 yqkK
MKELAJLE_02492 5.5e-242 mleA 1.1.1.38 C malic enzyme
MKELAJLE_02493 3.1e-235 mleN C Na H antiporter
MKELAJLE_02494 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
MKELAJLE_02495 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
MKELAJLE_02496 4.5e-58 ansR K Transcriptional regulator
MKELAJLE_02497 3e-223 yqxK 3.6.4.12 L DNA helicase
MKELAJLE_02498 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
MKELAJLE_02500 4.4e-169 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
MKELAJLE_02501 4e-14 yqkE S Protein of unknown function (DUF3886)
MKELAJLE_02502 2.4e-175 yqkD S COG1073 Hydrolases of the alpha beta superfamily
MKELAJLE_02503 9.4e-39 yqkC S Protein of unknown function (DUF2552)
MKELAJLE_02504 2.8e-54 yqkB S Belongs to the HesB IscA family
MKELAJLE_02505 4.7e-196 yqkA K GrpB protein
MKELAJLE_02506 8e-60 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
MKELAJLE_02507 3.6e-87 yqjY K acetyltransferase
MKELAJLE_02508 2.2e-49 S YolD-like protein
MKELAJLE_02509 3.1e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MKELAJLE_02511 5.2e-226 yqjV G Major Facilitator Superfamily
MKELAJLE_02513 7.2e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKELAJLE_02514 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
MKELAJLE_02515 2.4e-264 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
MKELAJLE_02516 3.5e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
MKELAJLE_02517 3.4e-180 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
MKELAJLE_02518 8.6e-148 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MKELAJLE_02519 0.0 rocB E arginine degradation protein
MKELAJLE_02520 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MKELAJLE_02521 9.6e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MKELAJLE_02522 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MKELAJLE_02523 1.6e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MKELAJLE_02524 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MKELAJLE_02525 7.3e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MKELAJLE_02526 4.5e-24 yqzJ
MKELAJLE_02527 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MKELAJLE_02528 3.6e-142 yqjF S Uncharacterized conserved protein (COG2071)
MKELAJLE_02529 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
MKELAJLE_02530 4.4e-291 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MKELAJLE_02531 2.2e-75 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
MKELAJLE_02533 1.4e-98 yqjB S protein conserved in bacteria
MKELAJLE_02534 1.1e-175 yqjA S Putative aromatic acid exporter C-terminal domain
MKELAJLE_02535 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MKELAJLE_02536 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
MKELAJLE_02537 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
MKELAJLE_02538 9.3e-77 yqiW S Belongs to the UPF0403 family
MKELAJLE_02539 8.8e-167 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MKELAJLE_02540 7.9e-208 norA EGP Major facilitator Superfamily
MKELAJLE_02541 2.6e-152 bmrR K helix_turn_helix, mercury resistance
MKELAJLE_02542 3.5e-233 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MKELAJLE_02543 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MKELAJLE_02544 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MKELAJLE_02545 3.4e-269 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MKELAJLE_02546 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
MKELAJLE_02547 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
MKELAJLE_02548 7.1e-156 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
MKELAJLE_02549 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
MKELAJLE_02550 4e-34 yqzF S Protein of unknown function (DUF2627)
MKELAJLE_02551 7.1e-164 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MKELAJLE_02552 5.7e-277 prpD 4.2.1.79 S 2-methylcitrate dehydratase
MKELAJLE_02553 8.1e-210 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
MKELAJLE_02554 1.8e-212 mmgC I acyl-CoA dehydrogenase
MKELAJLE_02555 4.7e-157 hbdA 1.1.1.157 I Dehydrogenase
MKELAJLE_02556 1.2e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
MKELAJLE_02557 1.8e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MKELAJLE_02558 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
MKELAJLE_02559 5.9e-27
MKELAJLE_02560 1.3e-215 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
MKELAJLE_02562 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MKELAJLE_02563 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
MKELAJLE_02564 0.0 recN L May be involved in recombinational repair of damaged DNA
MKELAJLE_02565 1.7e-78 argR K Regulates arginine biosynthesis genes
MKELAJLE_02566 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
MKELAJLE_02567 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MKELAJLE_02568 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MKELAJLE_02569 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MKELAJLE_02570 2.2e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MKELAJLE_02571 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MKELAJLE_02572 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MKELAJLE_02573 2.1e-67 yqhY S protein conserved in bacteria
MKELAJLE_02574 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MKELAJLE_02575 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MKELAJLE_02576 9.9e-91 spoIIIAH S SpoIIIAH-like protein
MKELAJLE_02577 6.9e-103 spoIIIAG S stage III sporulation protein AG
MKELAJLE_02578 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
MKELAJLE_02579 1.3e-197 spoIIIAE S stage III sporulation protein AE
MKELAJLE_02580 2.3e-58 spoIIIAD S Stage III sporulation protein AD
MKELAJLE_02581 7.6e-29 spoIIIAC S stage III sporulation protein AC
MKELAJLE_02582 2.9e-85 spoIIIAB S Stage III sporulation protein
MKELAJLE_02583 1.2e-171 spoIIIAA S stage III sporulation protein AA
MKELAJLE_02584 7.9e-37 yqhV S Protein of unknown function (DUF2619)
MKELAJLE_02585 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MKELAJLE_02586 8.9e-174 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
MKELAJLE_02587 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
MKELAJLE_02588 2.3e-93 yqhR S Conserved membrane protein YqhR
MKELAJLE_02589 9.4e-175 yqhQ S Protein of unknown function (DUF1385)
MKELAJLE_02590 2.2e-61 yqhP
MKELAJLE_02591 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
MKELAJLE_02592 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MKELAJLE_02593 5.2e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MKELAJLE_02594 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
MKELAJLE_02595 2.8e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MKELAJLE_02596 3.4e-255 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MKELAJLE_02597 9.6e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
MKELAJLE_02598 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
MKELAJLE_02599 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
MKELAJLE_02600 1.2e-24 sinI S Anti-repressor SinI
MKELAJLE_02601 1e-54 sinR K transcriptional
MKELAJLE_02602 2.3e-142 tasA S Cell division protein FtsN
MKELAJLE_02603 6.7e-59 sipW 3.4.21.89 U Signal peptidase
MKELAJLE_02604 2.1e-116 yqxM
MKELAJLE_02605 7.3e-54 yqzG S Protein of unknown function (DUF3889)
MKELAJLE_02606 1.4e-26 yqzE S YqzE-like protein
MKELAJLE_02607 3.7e-42 S ComG operon protein 7
MKELAJLE_02608 5.5e-49 comGF U Putative Competence protein ComGF
MKELAJLE_02609 1.1e-59 comGE
MKELAJLE_02610 4.4e-71 gspH NU protein transport across the cell outer membrane
MKELAJLE_02611 1.4e-47 comGC U Required for transformation and DNA binding
MKELAJLE_02612 1.6e-175 comGB NU COG1459 Type II secretory pathway, component PulF
MKELAJLE_02613 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MKELAJLE_02615 7.2e-175 corA P Mg2 transporter protein
MKELAJLE_02616 5.2e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MKELAJLE_02617 1.7e-151 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MKELAJLE_02619 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
MKELAJLE_02620 1.8e-37 yqgY S Protein of unknown function (DUF2626)
MKELAJLE_02621 1.9e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
MKELAJLE_02622 8.9e-23 yqgW S Protein of unknown function (DUF2759)
MKELAJLE_02623 6.9e-50 yqgV S Thiamine-binding protein
MKELAJLE_02624 2.7e-199 yqgU
MKELAJLE_02625 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
MKELAJLE_02626 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MKELAJLE_02627 5.2e-181 glcK 2.7.1.2 G Glucokinase
MKELAJLE_02628 3.1e-33 yqgQ S Protein conserved in bacteria
MKELAJLE_02629 1.4e-268 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
MKELAJLE_02630 2.5e-09 yqgO
MKELAJLE_02631 2.7e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MKELAJLE_02632 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MKELAJLE_02633 3.2e-203 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
MKELAJLE_02635 9.2e-51 yqzD
MKELAJLE_02636 1.9e-75 yqzC S YceG-like family
MKELAJLE_02637 9.8e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MKELAJLE_02638 6.4e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MKELAJLE_02639 4.4e-158 pstA P Phosphate transport system permease
MKELAJLE_02640 1.3e-160 pstC P probably responsible for the translocation of the substrate across the membrane
MKELAJLE_02641 5.3e-151 pstS P Phosphate
MKELAJLE_02642 0.0 pbpA 3.4.16.4 M penicillin-binding protein
MKELAJLE_02643 2.5e-231 yqgE EGP Major facilitator superfamily
MKELAJLE_02644 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
MKELAJLE_02645 4e-73 yqgC S protein conserved in bacteria
MKELAJLE_02646 8.5e-134 yqgB S Protein of unknown function (DUF1189)
MKELAJLE_02647 2.2e-75 yqgA
MKELAJLE_02648 5.2e-47 yqfZ M LysM domain
MKELAJLE_02649 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MKELAJLE_02650 4.3e-62 yqfX S membrane
MKELAJLE_02651 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
MKELAJLE_02652 1.9e-77 zur P Belongs to the Fur family
MKELAJLE_02653 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
MKELAJLE_02654 2.1e-36 yqfT S Protein of unknown function (DUF2624)
MKELAJLE_02655 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MKELAJLE_02656 1.7e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MKELAJLE_02657 2.9e-14 yqfQ S YqfQ-like protein
MKELAJLE_02658 2.6e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MKELAJLE_02659 5.1e-212 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MKELAJLE_02660 6.1e-117 trmK 2.1.1.217 S SAM-dependent methyltransferase
MKELAJLE_02661 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
MKELAJLE_02662 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MKELAJLE_02663 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MKELAJLE_02664 4.5e-88 yaiI S Belongs to the UPF0178 family
MKELAJLE_02665 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MKELAJLE_02666 4.5e-112 ccpN K CBS domain
MKELAJLE_02667 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MKELAJLE_02668 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MKELAJLE_02669 4.8e-145 recO L Involved in DNA repair and RecF pathway recombination
MKELAJLE_02670 8.4e-19 S YqzL-like protein
MKELAJLE_02671 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MKELAJLE_02672 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MKELAJLE_02673 1.6e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MKELAJLE_02674 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MKELAJLE_02675 0.0 yqfF S membrane-associated HD superfamily hydrolase
MKELAJLE_02677 1.1e-175 phoH T Phosphate starvation-inducible protein PhoH
MKELAJLE_02678 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
MKELAJLE_02679 2.7e-45 yqfC S sporulation protein YqfC
MKELAJLE_02680 6e-25 yqfB
MKELAJLE_02681 4.3e-122 yqfA S UPF0365 protein
MKELAJLE_02682 5.4e-229 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
MKELAJLE_02683 2.5e-61 yqeY S Yqey-like protein
MKELAJLE_02684 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MKELAJLE_02685 1.6e-158 yqeW P COG1283 Na phosphate symporter
MKELAJLE_02686 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
MKELAJLE_02687 1.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MKELAJLE_02688 5.4e-175 prmA J Methylates ribosomal protein L11
MKELAJLE_02689 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MKELAJLE_02690 0.0 dnaK O Heat shock 70 kDa protein
MKELAJLE_02691 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MKELAJLE_02692 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MKELAJLE_02693 4.8e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
MKELAJLE_02694 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MKELAJLE_02695 1e-54 yqxA S Protein of unknown function (DUF3679)
MKELAJLE_02696 6.9e-223 spoIIP M stage II sporulation protein P
MKELAJLE_02697 1.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MKELAJLE_02698 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
MKELAJLE_02699 1.1e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
MKELAJLE_02700 4.1e-15 S YqzM-like protein
MKELAJLE_02701 0.0 comEC S Competence protein ComEC
MKELAJLE_02702 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
MKELAJLE_02703 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
MKELAJLE_02704 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MKELAJLE_02705 2.9e-139 yqeM Q Methyltransferase
MKELAJLE_02706 6.9e-62 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MKELAJLE_02707 7.4e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
MKELAJLE_02708 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MKELAJLE_02709 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
MKELAJLE_02710 2.7e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MKELAJLE_02711 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MKELAJLE_02712 5.3e-95 yqeG S hydrolase of the HAD superfamily
MKELAJLE_02714 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
MKELAJLE_02715 2.1e-137 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MKELAJLE_02716 4.7e-106 yqeD S SNARE associated Golgi protein
MKELAJLE_02717 1.2e-171 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
MKELAJLE_02718 2.3e-133 yqeB
MKELAJLE_02719 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
MKELAJLE_02720 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKELAJLE_02721 1.4e-281 cisA2 L Recombinase
MKELAJLE_02722 1.8e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
MKELAJLE_02723 6e-183 arsB 1.20.4.1 P Arsenic resistance protein
MKELAJLE_02724 2.8e-73 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKELAJLE_02725 1.6e-54 arsR K ArsR family transcriptional regulator
MKELAJLE_02726 1.1e-152 yqcI S YqcI/YcgG family
MKELAJLE_02727 1.6e-96 S Tetratricopeptide repeat
MKELAJLE_02730 3.8e-277 A Pre-toxin TG
MKELAJLE_02731 1.1e-104 S Suppressor of fused protein (SUFU)
MKELAJLE_02733 5e-60
MKELAJLE_02735 1.1e-144 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
MKELAJLE_02736 2.6e-68 S Bacteriophage holin family
MKELAJLE_02737 4.8e-165 xepA
MKELAJLE_02738 1.3e-23
MKELAJLE_02739 4.1e-56 xkdW S XkdW protein
MKELAJLE_02740 2e-221
MKELAJLE_02741 9.6e-40
MKELAJLE_02742 9.9e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
MKELAJLE_02743 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MKELAJLE_02744 9.6e-71 xkdS S Protein of unknown function (DUF2634)
MKELAJLE_02745 1.8e-38 xkdR S Protein of unknown function (DUF2577)
MKELAJLE_02746 2.4e-181 yqbQ 3.2.1.96 G NLP P60 protein
MKELAJLE_02747 9e-114 xkdP S Lysin motif
MKELAJLE_02748 0.0 xkdO L Transglycosylase SLT domain
MKELAJLE_02749 1.8e-67 S Phage XkdN-like tail assembly chaperone protein, TAC
MKELAJLE_02751 3.6e-76 xkdM S Phage tail tube protein
MKELAJLE_02752 5.5e-256 xkdK S Phage tail sheath C-terminal domain
MKELAJLE_02753 3.2e-26
MKELAJLE_02754 1.4e-77
MKELAJLE_02755 4.3e-94 S Bacteriophage HK97-gp10, putative tail-component
MKELAJLE_02756 6.7e-65 yqbH S Domain of unknown function (DUF3599)
MKELAJLE_02757 2.1e-67 S Protein of unknown function (DUF3199)
MKELAJLE_02758 3.6e-51 S YqbF, hypothetical protein domain
MKELAJLE_02759 1.9e-167 xkdG S Phage capsid family
MKELAJLE_02760 5.1e-128 yqbD 2.1.1.72 L Putative phage serine protease XkdF
MKELAJLE_02761 2e-115
MKELAJLE_02762 5.7e-169 S Phage Mu protein F like protein
MKELAJLE_02763 5.9e-296 yqbA S portal protein
MKELAJLE_02764 2.4e-253 S phage terminase, large subunit
MKELAJLE_02765 6.3e-107 yqaS L DNA packaging
MKELAJLE_02767 6.5e-81 L Transposase
MKELAJLE_02768 1.6e-166
MKELAJLE_02769 2.1e-31 yqaO S Phage-like element PBSX protein XtrA
MKELAJLE_02770 7.2e-74 rusA L Endodeoxyribonuclease RusA
MKELAJLE_02772 5.9e-168 xkdC L IstB-like ATP binding protein
MKELAJLE_02773 4.7e-123 3.1.3.16 L DnaD domain protein
MKELAJLE_02774 2.5e-155 recT L RecT family
MKELAJLE_02775 1.5e-180 yqaJ L YqaJ-like viral recombinase domain
MKELAJLE_02779 1.2e-103
MKELAJLE_02781 6.5e-37 K Helix-turn-helix XRE-family like proteins
MKELAJLE_02782 1.1e-56 K sequence-specific DNA binding
MKELAJLE_02784 1e-101 adk 2.7.4.3 F adenylate kinase activity
MKELAJLE_02785 1.4e-100 yqaB E IrrE N-terminal-like domain
MKELAJLE_02786 2.2e-61 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKELAJLE_02787 2e-68 psiE S Protein PsiE homolog
MKELAJLE_02788 9e-237 yrkQ T Histidine kinase
MKELAJLE_02789 1.1e-127 T Transcriptional regulator
MKELAJLE_02790 8.2e-224 yrkO P Protein of unknown function (DUF418)
MKELAJLE_02791 6e-105 yrkN K Acetyltransferase (GNAT) family
MKELAJLE_02792 1.5e-97 ywrO S Flavodoxin-like fold
MKELAJLE_02793 2.8e-79 S Protein of unknown function with HXXEE motif
MKELAJLE_02794 4.3e-117 yrkJ S membrane transporter protein
MKELAJLE_02795 2.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
MKELAJLE_02796 2.3e-212 yrkH P Rhodanese Homology Domain
MKELAJLE_02797 1.7e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
MKELAJLE_02798 5.1e-84 yrkE O DsrE/DsrF/DrsH-like family
MKELAJLE_02799 7.8e-39 yrkD S protein conserved in bacteria
MKELAJLE_02800 2.6e-108 yrkC G Cupin domain
MKELAJLE_02801 4.8e-151 bltR K helix_turn_helix, mercury resistance
MKELAJLE_02802 3.5e-211 blt EGP Major facilitator Superfamily
MKELAJLE_02803 1.4e-83 bltD 2.3.1.57 K FR47-like protein
MKELAJLE_02804 4.5e-236 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MKELAJLE_02805 2.1e-17 S YrzO-like protein
MKELAJLE_02806 1.7e-171 yrdR EG EamA-like transporter family
MKELAJLE_02807 5.9e-160 yrdQ K Transcriptional regulator
MKELAJLE_02808 2e-199 trkA P Oxidoreductase
MKELAJLE_02809 3.5e-158 czcD P COG1230 Co Zn Cd efflux system component
MKELAJLE_02810 1.3e-66 yodA S tautomerase
MKELAJLE_02811 7.7e-163 gltR K LysR substrate binding domain
MKELAJLE_02813 1.5e-231 brnQ E Component of the transport system for branched-chain amino acids
MKELAJLE_02814 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
MKELAJLE_02815 3.3e-138 azlC E AzlC protein
MKELAJLE_02816 2.2e-79 bkdR K helix_turn_helix ASNC type
MKELAJLE_02817 4.1e-46 yrdF K ribonuclease inhibitor
MKELAJLE_02818 4.1e-231 cypA C Cytochrome P450
MKELAJLE_02820 3.1e-101 yrdC 3.5.1.19 Q Isochorismatase family
MKELAJLE_02821 1.9e-57 S Protein of unknown function (DUF2568)
MKELAJLE_02822 1.2e-91 yrdA S DinB family
MKELAJLE_02823 7.6e-168 aadK G Streptomycin adenylyltransferase
MKELAJLE_02824 1.5e-194 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MKELAJLE_02825 7.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MKELAJLE_02826 3e-125 yrpD S Domain of unknown function, YrpD
MKELAJLE_02828 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
MKELAJLE_02829 2.9e-66 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
MKELAJLE_02830 4.5e-188 yrpG C Aldo/keto reductase family
MKELAJLE_02831 9.5e-226 yraO C Citrate transporter
MKELAJLE_02832 1.2e-163 yraN K Transcriptional regulator
MKELAJLE_02833 2.4e-206 yraM S PrpF protein
MKELAJLE_02835 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
MKELAJLE_02836 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKELAJLE_02837 3.2e-155 S Alpha beta hydrolase
MKELAJLE_02838 1.7e-60 T sh3 domain protein
MKELAJLE_02839 2.4e-61 T sh3 domain protein
MKELAJLE_02840 1.3e-66 E Glyoxalase-like domain
MKELAJLE_02841 5.3e-37 yraG
MKELAJLE_02842 6.4e-63 yraF M Spore coat protein
MKELAJLE_02843 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MKELAJLE_02844 2.6e-26 yraE
MKELAJLE_02845 1.1e-49 yraD M Spore coat protein
MKELAJLE_02846 4.3e-47 yraB K helix_turn_helix, mercury resistance
MKELAJLE_02847 3.2e-29 yphJ 4.1.1.44 S peroxiredoxin activity
MKELAJLE_02848 1.9e-200 adhA 1.1.1.1 C alcohol dehydrogenase
MKELAJLE_02849 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
MKELAJLE_02850 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
MKELAJLE_02851 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
MKELAJLE_02852 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
MKELAJLE_02853 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
MKELAJLE_02854 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
MKELAJLE_02855 0.0 levR K PTS system fructose IIA component
MKELAJLE_02856 1.6e-255 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
MKELAJLE_02857 3.6e-106 yrhP E LysE type translocator
MKELAJLE_02858 1.1e-150 yrhO K Archaeal transcriptional regulator TrmB
MKELAJLE_02859 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
MKELAJLE_02860 1.7e-151 rsiV S Protein of unknown function (DUF3298)
MKELAJLE_02861 0.0 yrhL I Acyltransferase family
MKELAJLE_02862 1.5e-46 yrhK S YrhK-like protein
MKELAJLE_02863 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
MKELAJLE_02864 4.8e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
MKELAJLE_02865 4.5e-97 yrhH Q methyltransferase
MKELAJLE_02868 1.8e-142 focA P Formate nitrite
MKELAJLE_02869 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
MKELAJLE_02870 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
MKELAJLE_02871 1.4e-78 yrhD S Protein of unknown function (DUF1641)
MKELAJLE_02872 4.6e-35 yrhC S YrhC-like protein
MKELAJLE_02873 2.6e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MKELAJLE_02874 1.2e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
MKELAJLE_02875 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MKELAJLE_02876 1.2e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
MKELAJLE_02877 7e-27 yrzA S Protein of unknown function (DUF2536)
MKELAJLE_02878 4.2e-63 yrrS S Protein of unknown function (DUF1510)
MKELAJLE_02879 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
MKELAJLE_02880 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MKELAJLE_02881 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
MKELAJLE_02882 2.7e-246 yegQ O COG0826 Collagenase and related proteases
MKELAJLE_02883 7.8e-174 yegQ O Peptidase U32
MKELAJLE_02884 5.9e-120 yrrM 2.1.1.104 S O-methyltransferase
MKELAJLE_02885 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MKELAJLE_02886 1.2e-45 yrzB S Belongs to the UPF0473 family
MKELAJLE_02887 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MKELAJLE_02888 1.7e-41 yrzL S Belongs to the UPF0297 family
MKELAJLE_02889 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MKELAJLE_02890 2.7e-170 yrrI S AI-2E family transporter
MKELAJLE_02891 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MKELAJLE_02892 5.1e-145 glnH ET Belongs to the bacterial solute-binding protein 3 family
MKELAJLE_02893 3.6e-109 gluC P ABC transporter
MKELAJLE_02894 7.6e-107 glnP P ABC transporter
MKELAJLE_02895 8e-08 S Protein of unknown function (DUF3918)
MKELAJLE_02896 9.8e-31 yrzR
MKELAJLE_02897 1.8e-83 yrrD S protein conserved in bacteria
MKELAJLE_02898 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MKELAJLE_02899 1.4e-15 S COG0457 FOG TPR repeat
MKELAJLE_02900 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MKELAJLE_02901 4.7e-213 iscS 2.8.1.7 E Cysteine desulfurase
MKELAJLE_02902 1.2e-70 cymR K Transcriptional regulator
MKELAJLE_02903 2e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MKELAJLE_02904 2.8e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MKELAJLE_02905 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MKELAJLE_02906 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
MKELAJLE_02908 3.9e-263 lytH 3.5.1.28 M COG3103 SH3 domain protein
MKELAJLE_02909 1.9e-68 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MKELAJLE_02910 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MKELAJLE_02911 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MKELAJLE_02912 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MKELAJLE_02913 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
MKELAJLE_02914 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
MKELAJLE_02915 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MKELAJLE_02916 9.4e-49 yrzD S Post-transcriptional regulator
MKELAJLE_02917 5.7e-270 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MKELAJLE_02918 2.2e-114 yrbG S membrane
MKELAJLE_02919 1.2e-74 yrzE S Protein of unknown function (DUF3792)
MKELAJLE_02920 1.1e-38 yajC U Preprotein translocase subunit YajC
MKELAJLE_02921 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MKELAJLE_02922 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MKELAJLE_02923 2.6e-18 yrzS S Protein of unknown function (DUF2905)
MKELAJLE_02924 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MKELAJLE_02925 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MKELAJLE_02926 4.8e-93 bofC S BofC C-terminal domain
MKELAJLE_02927 5.3e-253 csbX EGP Major facilitator Superfamily
MKELAJLE_02928 1.3e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
MKELAJLE_02929 6.5e-119 yrzF T serine threonine protein kinase
MKELAJLE_02931 2.6e-35 S Family of unknown function (DUF5412)
MKELAJLE_02932 1.8e-262 alsT E Sodium alanine symporter
MKELAJLE_02933 1.9e-127 yebC K transcriptional regulatory protein
MKELAJLE_02934 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MKELAJLE_02935 9.8e-158 safA M spore coat assembly protein SafA
MKELAJLE_02936 2.8e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MKELAJLE_02937 5.4e-161 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
MKELAJLE_02938 2.7e-307 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
MKELAJLE_02939 1.2e-230 nifS 2.8.1.7 E Cysteine desulfurase
MKELAJLE_02940 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
MKELAJLE_02941 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
MKELAJLE_02942 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
MKELAJLE_02943 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MKELAJLE_02944 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
MKELAJLE_02945 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MKELAJLE_02946 4.1e-56 ysxB J ribosomal protein
MKELAJLE_02947 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
MKELAJLE_02948 9.2e-161 spoIVFB S Stage IV sporulation protein
MKELAJLE_02949 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
MKELAJLE_02950 2.5e-144 minD D Belongs to the ParA family
MKELAJLE_02951 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MKELAJLE_02952 1.4e-84 mreD M shape-determining protein
MKELAJLE_02953 2.8e-157 mreC M Involved in formation and maintenance of cell shape
MKELAJLE_02954 1.8e-184 mreB D Rod shape-determining protein MreB
MKELAJLE_02955 5.9e-126 radC E Belongs to the UPF0758 family
MKELAJLE_02956 2.8e-102 maf D septum formation protein Maf
MKELAJLE_02957 1.1e-168 spoIIB S Sporulation related domain
MKELAJLE_02958 6.6e-85 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MKELAJLE_02959 4.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MKELAJLE_02960 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MKELAJLE_02961 1.6e-25
MKELAJLE_02962 1.6e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MKELAJLE_02963 1.9e-226 spoVID M stage VI sporulation protein D
MKELAJLE_02964 4.6e-249 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
MKELAJLE_02965 5.6e-183 hemB 4.2.1.24 H Belongs to the ALAD family
MKELAJLE_02966 4.4e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
MKELAJLE_02967 3e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MKELAJLE_02968 3.6e-146 hemX O cytochrome C
MKELAJLE_02969 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MKELAJLE_02970 1.4e-89 ysxD
MKELAJLE_02971 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
MKELAJLE_02972 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MKELAJLE_02973 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
MKELAJLE_02974 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MKELAJLE_02975 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MKELAJLE_02976 2.3e-187 ysoA H Tetratricopeptide repeat
MKELAJLE_02977 8.1e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MKELAJLE_02978 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MKELAJLE_02979 3.3e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MKELAJLE_02980 4e-292 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MKELAJLE_02981 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MKELAJLE_02982 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
MKELAJLE_02983 0.0 ilvB 2.2.1.6 E Acetolactate synthase
MKELAJLE_02985 7.6e-82 ysnE K acetyltransferase
MKELAJLE_02986 9.1e-134 ysnF S protein conserved in bacteria
MKELAJLE_02988 1.4e-92 ysnB S Phosphoesterase
MKELAJLE_02989 4.5e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MKELAJLE_02990 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MKELAJLE_02991 2.9e-196 gerM S COG5401 Spore germination protein
MKELAJLE_02992 2.1e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MKELAJLE_02993 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
MKELAJLE_02994 3.3e-30 gerE K Transcriptional regulator
MKELAJLE_02995 7.7e-79 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
MKELAJLE_02996 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
MKELAJLE_02997 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
MKELAJLE_02998 2.4e-107 sdhC C succinate dehydrogenase
MKELAJLE_02999 1.2e-79 yslB S Protein of unknown function (DUF2507)
MKELAJLE_03000 1.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
MKELAJLE_03001 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MKELAJLE_03002 2e-52 trxA O Belongs to the thioredoxin family
MKELAJLE_03003 4e-305 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
MKELAJLE_03005 4.2e-178 etfA C Electron transfer flavoprotein
MKELAJLE_03006 1.2e-135 etfB C Electron transfer flavoprotein
MKELAJLE_03007 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
MKELAJLE_03008 2.7e-100 fadR K Transcriptional regulator
MKELAJLE_03009 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MKELAJLE_03010 7.3e-68 yshE S membrane
MKELAJLE_03011 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MKELAJLE_03012 0.0 polX L COG1796 DNA polymerase IV (family X)
MKELAJLE_03013 1.3e-85 cvpA S membrane protein, required for colicin V production
MKELAJLE_03014 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MKELAJLE_03015 4e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MKELAJLE_03016 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MKELAJLE_03017 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MKELAJLE_03018 3.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MKELAJLE_03019 2.6e-32 sspI S Belongs to the SspI family
MKELAJLE_03020 4.4e-208 ysfB KT regulator
MKELAJLE_03021 7.2e-264 glcD 1.1.3.15 C Glycolate oxidase subunit
MKELAJLE_03022 5.6e-258 glcF C Glycolate oxidase
MKELAJLE_03023 3.6e-38 ysfE 4.4.1.5 E lactoylglutathione lyase activity
MKELAJLE_03025 0.0 cstA T Carbon starvation protein
MKELAJLE_03026 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
MKELAJLE_03027 3.4e-144 araQ G transport system permease
MKELAJLE_03028 1.4e-167 araP G carbohydrate transport
MKELAJLE_03029 2.8e-254 araN G carbohydrate transport
MKELAJLE_03030 5e-226 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
MKELAJLE_03031 4.1e-147 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
MKELAJLE_03032 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MKELAJLE_03033 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
MKELAJLE_03034 1.9e-294 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
MKELAJLE_03035 2.1e-190 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
MKELAJLE_03036 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
MKELAJLE_03037 9.2e-68 ysdB S Sigma-w pathway protein YsdB
MKELAJLE_03038 7.5e-45 ysdA S Membrane
MKELAJLE_03039 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MKELAJLE_03040 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MKELAJLE_03041 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MKELAJLE_03043 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MKELAJLE_03044 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MKELAJLE_03045 6.3e-131 lytT T COG3279 Response regulator of the LytR AlgR family
MKELAJLE_03046 0.0 lytS 2.7.13.3 T Histidine kinase
MKELAJLE_03047 1.5e-149 ysaA S HAD-hyrolase-like
MKELAJLE_03048 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MKELAJLE_03049 3.8e-159 ytxC S YtxC-like family
MKELAJLE_03050 4.9e-111 ytxB S SNARE associated Golgi protein
MKELAJLE_03051 3e-173 dnaI L Primosomal protein DnaI
MKELAJLE_03052 3.5e-266 dnaB L Membrane attachment protein
MKELAJLE_03053 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MKELAJLE_03054 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MKELAJLE_03055 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MKELAJLE_03056 9.9e-67 ytcD K Transcriptional regulator
MKELAJLE_03057 4.9e-205 ytbD EGP Major facilitator Superfamily
MKELAJLE_03058 8.9e-161 ytbE S reductase
MKELAJLE_03059 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MKELAJLE_03060 1.1e-107 ytaF P Probably functions as a manganese efflux pump
MKELAJLE_03061 2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MKELAJLE_03062 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MKELAJLE_03063 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
MKELAJLE_03064 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKELAJLE_03065 1.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
MKELAJLE_03066 1.8e-242 icd 1.1.1.42 C isocitrate
MKELAJLE_03067 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
MKELAJLE_03068 4.7e-71 yeaL S membrane
MKELAJLE_03069 2.6e-192 ytvI S sporulation integral membrane protein YtvI
MKELAJLE_03070 1.8e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
MKELAJLE_03071 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MKELAJLE_03072 3.4e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MKELAJLE_03073 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MKELAJLE_03074 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MKELAJLE_03075 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
MKELAJLE_03076 0.0 dnaE 2.7.7.7 L DNA polymerase
MKELAJLE_03077 3.2e-56 ytrH S Sporulation protein YtrH
MKELAJLE_03078 8.2e-69 ytrI
MKELAJLE_03079 9.2e-29
MKELAJLE_03080 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
MKELAJLE_03081 2.4e-47 ytpI S YtpI-like protein
MKELAJLE_03082 8e-241 ytoI K transcriptional regulator containing CBS domains
MKELAJLE_03083 1.2e-158 ytnM S membrane transporter protein
MKELAJLE_03084 4.9e-240 ytnL 3.5.1.47 E hydrolase activity
MKELAJLE_03085 6.3e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
MKELAJLE_03086 1e-256 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKELAJLE_03087 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
MKELAJLE_03088 1.2e-185 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKELAJLE_03089 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MKELAJLE_03090 7.6e-121 tcyM U Binding-protein-dependent transport system inner membrane component
MKELAJLE_03091 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
MKELAJLE_03092 1.5e-149 tcyK M Bacterial periplasmic substrate-binding proteins
MKELAJLE_03093 9.5e-152 tcyK ET Bacterial periplasmic substrate-binding proteins
MKELAJLE_03094 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
MKELAJLE_03095 2.9e-173 ytlI K LysR substrate binding domain
MKELAJLE_03096 1.7e-130 ytkL S Belongs to the UPF0173 family
MKELAJLE_03097 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKELAJLE_03099 3.1e-267 argH 4.3.2.1 E argininosuccinate lyase
MKELAJLE_03100 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MKELAJLE_03101 3.6e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
MKELAJLE_03102 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MKELAJLE_03103 7e-165 ytxK 2.1.1.72 L DNA methylase
MKELAJLE_03104 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MKELAJLE_03105 8.7e-70 ytfJ S Sporulation protein YtfJ
MKELAJLE_03106 5.6e-116 ytfI S Protein of unknown function (DUF2953)
MKELAJLE_03107 1.3e-87 yteJ S RDD family
MKELAJLE_03108 2.4e-181 sppA OU signal peptide peptidase SppA
MKELAJLE_03109 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MKELAJLE_03110 0.0 ytcJ S amidohydrolase
MKELAJLE_03111 2e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MKELAJLE_03112 2e-29 sspB S spore protein
MKELAJLE_03113 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MKELAJLE_03114 2.2e-210 iscS2 2.8.1.7 E Cysteine desulfurase
MKELAJLE_03115 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
MKELAJLE_03116 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MKELAJLE_03117 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
MKELAJLE_03118 3.4e-109 yttP K Transcriptional regulator
MKELAJLE_03119 1.2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
MKELAJLE_03120 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
MKELAJLE_03121 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MKELAJLE_03123 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MKELAJLE_03124 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MKELAJLE_03125 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MKELAJLE_03126 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
MKELAJLE_03127 1.9e-225 acuC BQ histone deacetylase
MKELAJLE_03128 1.4e-125 motS N Flagellar motor protein
MKELAJLE_03129 7.1e-147 motA N flagellar motor
MKELAJLE_03130 1.7e-182 ccpA K catabolite control protein A
MKELAJLE_03131 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MKELAJLE_03132 4.4e-55 ytxJ O Protein of unknown function (DUF2847)
MKELAJLE_03133 6.6e-17 ytxH S COG4980 Gas vesicle protein
MKELAJLE_03134 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MKELAJLE_03135 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MKELAJLE_03136 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
MKELAJLE_03137 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MKELAJLE_03138 9.8e-149 ytpQ S Belongs to the UPF0354 family
MKELAJLE_03139 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MKELAJLE_03140 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
MKELAJLE_03141 4.7e-207 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
MKELAJLE_03142 9.8e-52 ytzB S small secreted protein
MKELAJLE_03143 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
MKELAJLE_03144 6.4e-151 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
MKELAJLE_03145 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MKELAJLE_03146 2e-45 ytzH S YtzH-like protein
MKELAJLE_03147 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
MKELAJLE_03148 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
MKELAJLE_03149 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
MKELAJLE_03150 1.3e-165 ytlQ
MKELAJLE_03151 4.3e-103 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MKELAJLE_03152 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MKELAJLE_03153 7.1e-272 pepV 3.5.1.18 E Dipeptidase
MKELAJLE_03154 7.2e-226 pbuO S permease
MKELAJLE_03155 3.9e-207 ythQ U Bacterial ABC transporter protein EcsB
MKELAJLE_03156 4.3e-132 ythP V ABC transporter
MKELAJLE_03157 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
MKELAJLE_03158 2.6e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MKELAJLE_03159 1.9e-281 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MKELAJLE_03160 8.2e-232 ytfP S HI0933-like protein
MKELAJLE_03161 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
MKELAJLE_03162 3.1e-26 yteV S Sporulation protein Cse60
MKELAJLE_03163 4.8e-117 yteU S Integral membrane protein
MKELAJLE_03164 9.2e-258 yteT S Oxidoreductase family, C-terminal alpha/beta domain
MKELAJLE_03165 4.6e-73 yteS G transport
MKELAJLE_03166 4.7e-226 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
MKELAJLE_03167 2e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
MKELAJLE_03168 0.0 ytdP K Transcriptional regulator
MKELAJLE_03169 1.2e-290 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
MKELAJLE_03170 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
MKELAJLE_03171 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
MKELAJLE_03172 1.9e-225 bioI 1.14.14.46 C Cytochrome P450
MKELAJLE_03173 2.2e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MKELAJLE_03174 3.7e-128 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MKELAJLE_03175 1.4e-220 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MKELAJLE_03176 2.4e-261 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
MKELAJLE_03177 1.6e-142 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MKELAJLE_03178 1.3e-173 ytaP S Acetyl xylan esterase (AXE1)
MKELAJLE_03179 2.3e-190 msmR K Transcriptional regulator
MKELAJLE_03180 2.3e-248 msmE G Bacterial extracellular solute-binding protein
MKELAJLE_03181 3.7e-168 amyD P ABC transporter
MKELAJLE_03182 1.5e-144 amyC P ABC transporter (permease)
MKELAJLE_03183 4e-253 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
MKELAJLE_03184 2.1e-51 ytwF P Sulfurtransferase
MKELAJLE_03185 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MKELAJLE_03186 7.7e-55 ytvB S Protein of unknown function (DUF4257)
MKELAJLE_03187 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
MKELAJLE_03188 2.1e-211 yttB EGP Major facilitator Superfamily
MKELAJLE_03189 1.8e-43 yttA 2.7.13.3 S Pfam Transposase IS66
MKELAJLE_03190 0.0 bceB V ABC transporter (permease)
MKELAJLE_03191 1.1e-138 bceA V ABC transporter, ATP-binding protein
MKELAJLE_03192 5.6e-186 T PhoQ Sensor
MKELAJLE_03193 5.2e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKELAJLE_03194 8.5e-235 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
MKELAJLE_03195 3.1e-127 ytrE V ABC transporter, ATP-binding protein
MKELAJLE_03196 5.9e-148
MKELAJLE_03197 6.1e-169 P ABC-2 family transporter protein
MKELAJLE_03198 1.1e-161 ytrB P abc transporter atp-binding protein
MKELAJLE_03199 5.1e-66 ytrA K GntR family transcriptional regulator
MKELAJLE_03201 6.7e-41 ytzC S Protein of unknown function (DUF2524)
MKELAJLE_03202 2.1e-190 yhcC S Fe-S oxidoreductase
MKELAJLE_03203 3.3e-106 ytqB J Putative rRNA methylase
MKELAJLE_03204 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
MKELAJLE_03205 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
MKELAJLE_03206 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MKELAJLE_03207 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
MKELAJLE_03208 0.0 asnB 6.3.5.4 E Asparagine synthase
MKELAJLE_03209 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MKELAJLE_03210 2.2e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MKELAJLE_03211 1.2e-38 ytmB S Protein of unknown function (DUF2584)
MKELAJLE_03212 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
MKELAJLE_03213 5e-190 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MKELAJLE_03214 1.4e-144 ytlC P ABC transporter
MKELAJLE_03215 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MKELAJLE_03216 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
MKELAJLE_03217 5.4e-63 ytkC S Bacteriophage holin family
MKELAJLE_03218 2.1e-76 dps P Belongs to the Dps family
MKELAJLE_03220 3.6e-73 ytkA S YtkA-like
MKELAJLE_03221 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MKELAJLE_03222 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
MKELAJLE_03223 3.6e-41 rpmE2 J Ribosomal protein L31
MKELAJLE_03224 4.7e-249 cydA 1.10.3.14 C oxidase, subunit
MKELAJLE_03225 7.3e-189 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
MKELAJLE_03226 1.1e-24 S Domain of Unknown Function (DUF1540)
MKELAJLE_03227 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
MKELAJLE_03228 3.2e-234 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MKELAJLE_03229 1.2e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MKELAJLE_03230 1.8e-170 troA P Belongs to the bacterial solute-binding protein 9 family
MKELAJLE_03231 1.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MKELAJLE_03232 2.4e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MKELAJLE_03233 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MKELAJLE_03234 3.8e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MKELAJLE_03235 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MKELAJLE_03236 8.5e-273 menF 5.4.4.2 HQ Isochorismate synthase
MKELAJLE_03237 2.6e-132 dksA T COG1734 DnaK suppressor protein
MKELAJLE_03238 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
MKELAJLE_03239 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MKELAJLE_03240 3.9e-181 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
MKELAJLE_03241 3.6e-235 ytcC M Glycosyltransferase Family 4
MKELAJLE_03243 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
MKELAJLE_03244 1.8e-217 cotSA M Glycosyl transferases group 1
MKELAJLE_03245 1.8e-206 cotI S Spore coat protein
MKELAJLE_03246 9.9e-77 tspO T membrane
MKELAJLE_03247 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MKELAJLE_03248 4.3e-288 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
MKELAJLE_03249 1.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
MKELAJLE_03250 3.6e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MKELAJLE_03251 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MKELAJLE_03260 7.8e-08
MKELAJLE_03261 1.3e-09
MKELAJLE_03268 2e-08
MKELAJLE_03273 3.4e-39 S COG NOG14552 non supervised orthologous group
MKELAJLE_03274 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
MKELAJLE_03275 3.4e-94 M1-753 M FR47-like protein
MKELAJLE_03276 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
MKELAJLE_03277 1.4e-77 yuaF OU Membrane protein implicated in regulation of membrane protease activity
MKELAJLE_03278 3.9e-84 yuaE S DinB superfamily
MKELAJLE_03279 7.9e-108 yuaD
MKELAJLE_03280 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
MKELAJLE_03281 8e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
MKELAJLE_03282 1.1e-95 yuaC K Belongs to the GbsR family
MKELAJLE_03283 2.2e-91 yuaB
MKELAJLE_03284 5e-122 ktrA P COG0569 K transport systems, NAD-binding component
MKELAJLE_03285 5.4e-237 ktrB P Potassium
MKELAJLE_03286 1e-38 yiaA S yiaA/B two helix domain
MKELAJLE_03287 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MKELAJLE_03288 6.2e-277 yubD P Major Facilitator Superfamily
MKELAJLE_03289 2.6e-88 cdoA 1.13.11.20 S Cysteine dioxygenase type I
MKELAJLE_03291 1.2e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MKELAJLE_03292 6.3e-197 yubA S transporter activity
MKELAJLE_03293 3.3e-183 ygjR S Oxidoreductase
MKELAJLE_03294 1.4e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
MKELAJLE_03295 2.5e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
MKELAJLE_03296 1.3e-281 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
MKELAJLE_03297 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
MKELAJLE_03298 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
MKELAJLE_03299 5.1e-239 mcpA NT chemotaxis protein
MKELAJLE_03300 2.2e-295 mcpA NT chemotaxis protein
MKELAJLE_03301 1.5e-222 mcpA NT chemotaxis protein
MKELAJLE_03302 3.2e-225 mcpA NT chemotaxis protein
MKELAJLE_03303 2.6e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
MKELAJLE_03304 1e-35
MKELAJLE_03305 2.1e-72 yugU S Uncharacterised protein family UPF0047
MKELAJLE_03306 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
MKELAJLE_03307 2.6e-236 yugS S COG1253 Hemolysins and related proteins containing CBS domains
MKELAJLE_03308 1.4e-116 yugP S Zn-dependent protease
MKELAJLE_03309 4.6e-39
MKELAJLE_03310 1.1e-53 mstX S Membrane-integrating protein Mistic
MKELAJLE_03311 1.7e-182 yugO P COG1226 Kef-type K transport systems
MKELAJLE_03312 1.3e-72 yugN S YugN-like family
MKELAJLE_03314 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
MKELAJLE_03315 2.8e-229 yugK C Dehydrogenase
MKELAJLE_03316 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
MKELAJLE_03317 1.1e-34 yuzA S Domain of unknown function (DUF378)
MKELAJLE_03318 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
MKELAJLE_03319 4.3e-200 yugH 2.6.1.1 E Aminotransferase
MKELAJLE_03320 1.6e-85 alaR K Transcriptional regulator
MKELAJLE_03321 1e-156 yugF I Hydrolase
MKELAJLE_03322 9.8e-42 yugE S Domain of unknown function (DUF1871)
MKELAJLE_03323 1.8e-228 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MKELAJLE_03324 4.6e-233 T PhoQ Sensor
MKELAJLE_03325 2e-70 kapB G Kinase associated protein B
MKELAJLE_03326 1.9e-115 kapD L the KinA pathway to sporulation
MKELAJLE_03328 3.5e-186 yuxJ EGP Major facilitator Superfamily
MKELAJLE_03329 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
MKELAJLE_03330 6.3e-75 yuxK S protein conserved in bacteria
MKELAJLE_03331 6.3e-78 yufK S Family of unknown function (DUF5366)
MKELAJLE_03332 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MKELAJLE_03333 2.3e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
MKELAJLE_03334 3.4e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
MKELAJLE_03335 1.1e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
MKELAJLE_03336 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
MKELAJLE_03337 4.5e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
MKELAJLE_03338 1.3e-233 maeN C COG3493 Na citrate symporter
MKELAJLE_03339 1.9e-14
MKELAJLE_03340 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MKELAJLE_03341 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MKELAJLE_03342 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MKELAJLE_03343 3.8e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MKELAJLE_03344 4.8e-79 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MKELAJLE_03345 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MKELAJLE_03346 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
MKELAJLE_03347 9.2e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
MKELAJLE_03348 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKELAJLE_03349 0.0 comP 2.7.13.3 T Histidine kinase
MKELAJLE_03351 2.5e-162 comQ H Polyprenyl synthetase
MKELAJLE_03353 1.1e-22 yuzC
MKELAJLE_03354 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
MKELAJLE_03355 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MKELAJLE_03356 2.9e-104 pncA Q COG1335 Amidases related to nicotinamidase
MKELAJLE_03357 1.6e-67 yueI S Protein of unknown function (DUF1694)
MKELAJLE_03358 7.4e-39 yueH S YueH-like protein
MKELAJLE_03359 2.1e-32 yueG S Spore germination protein gerPA/gerPF
MKELAJLE_03360 1.9e-190 yueF S transporter activity
MKELAJLE_03361 6.1e-72 S Protein of unknown function (DUF2283)
MKELAJLE_03362 2.9e-24 S Protein of unknown function (DUF2642)
MKELAJLE_03363 4.8e-96 yueE S phosphohydrolase
MKELAJLE_03364 4.4e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKELAJLE_03365 6.6e-65 yueC S Family of unknown function (DUF5383)
MKELAJLE_03366 0.0 esaA S type VII secretion protein EsaA
MKELAJLE_03367 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MKELAJLE_03368 2.3e-211 essB S WXG100 protein secretion system (Wss), protein YukC
MKELAJLE_03369 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
MKELAJLE_03370 2.8e-45 esxA S Belongs to the WXG100 family
MKELAJLE_03371 6.5e-229 yukF QT Transcriptional regulator
MKELAJLE_03372 1.2e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
MKELAJLE_03373 1.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
MKELAJLE_03374 3.8e-36 mbtH S MbtH-like protein
MKELAJLE_03375 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKELAJLE_03376 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
MKELAJLE_03377 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
MKELAJLE_03378 2.3e-226 entC 5.4.4.2 HQ Isochorismate synthase
MKELAJLE_03379 7.3e-141 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MKELAJLE_03380 1.3e-167 besA S Putative esterase
MKELAJLE_03381 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
MKELAJLE_03382 1.1e-93 bioY S Biotin biosynthesis protein
MKELAJLE_03383 3.9e-211 yuiF S antiporter
MKELAJLE_03384 1.5e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MKELAJLE_03385 1.2e-77 yuiD S protein conserved in bacteria
MKELAJLE_03386 9.5e-118 yuiC S protein conserved in bacteria
MKELAJLE_03387 8.4e-27 yuiB S Putative membrane protein
MKELAJLE_03388 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
MKELAJLE_03389 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
MKELAJLE_03391 4.9e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MKELAJLE_03392 9e-118 paiB K Putative FMN-binding domain
MKELAJLE_03393 4.7e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKELAJLE_03394 3.7e-63 erpA S Belongs to the HesB IscA family
MKELAJLE_03395 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MKELAJLE_03396 2.4e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MKELAJLE_03397 3.2e-39 yuzB S Belongs to the UPF0349 family
MKELAJLE_03398 1.2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
MKELAJLE_03399 3.5e-57 yuzD S protein conserved in bacteria
MKELAJLE_03400 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
MKELAJLE_03401 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
MKELAJLE_03402 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MKELAJLE_03403 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MKELAJLE_03404 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
MKELAJLE_03405 2e-199 yutH S Spore coat protein
MKELAJLE_03406 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
MKELAJLE_03407 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MKELAJLE_03408 1e-75 yutE S Protein of unknown function DUF86
MKELAJLE_03409 9.7e-48 yutD S protein conserved in bacteria
MKELAJLE_03410 4.9e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MKELAJLE_03411 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MKELAJLE_03412 4.5e-196 lytH M Peptidase, M23
MKELAJLE_03413 8.4e-134 yunB S Sporulation protein YunB (Spo_YunB)
MKELAJLE_03414 4.8e-48 yunC S Domain of unknown function (DUF1805)
MKELAJLE_03415 5.8e-266 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
MKELAJLE_03416 2e-141 yunE S membrane transporter protein
MKELAJLE_03417 4.3e-171 yunF S Protein of unknown function DUF72
MKELAJLE_03418 3e-62 yunG
MKELAJLE_03419 1e-259 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
MKELAJLE_03420 1.2e-302 pucR QT COG2508 Regulator of polyketide synthase expression
MKELAJLE_03421 2.1e-236 pbuX F Permease family
MKELAJLE_03422 1.3e-224 pbuX F xanthine
MKELAJLE_03423 6.6e-284 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
MKELAJLE_03424 7.3e-61 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
MKELAJLE_03425 7.9e-99 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
MKELAJLE_03426 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MKELAJLE_03427 3.4e-152 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
MKELAJLE_03428 3.6e-111 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
MKELAJLE_03429 1.7e-190 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MKELAJLE_03431 1.9e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
MKELAJLE_03432 1.6e-238 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MKELAJLE_03433 2.4e-169 bsn L Ribonuclease
MKELAJLE_03434 1.2e-205 msmX P Belongs to the ABC transporter superfamily
MKELAJLE_03435 1.1e-135 yurK K UTRA
MKELAJLE_03436 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
MKELAJLE_03437 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
MKELAJLE_03438 1.4e-156 yurN G Binding-protein-dependent transport system inner membrane component
MKELAJLE_03439 1.3e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
MKELAJLE_03440 1.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
MKELAJLE_03441 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
MKELAJLE_03442 1.8e-209 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
MKELAJLE_03444 1e-41
MKELAJLE_03445 7.6e-67 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKELAJLE_03446 3.5e-271 sufB O FeS cluster assembly
MKELAJLE_03447 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
MKELAJLE_03448 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MKELAJLE_03449 1.4e-245 sufD O assembly protein SufD
MKELAJLE_03450 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MKELAJLE_03451 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MKELAJLE_03452 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
MKELAJLE_03453 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
MKELAJLE_03454 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MKELAJLE_03455 2.4e-56 yusD S SCP-2 sterol transfer family
MKELAJLE_03456 5.6e-55 traF CO Thioredoxin
MKELAJLE_03457 3.3e-74 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
MKELAJLE_03458 1.1e-39 yusG S Protein of unknown function (DUF2553)
MKELAJLE_03459 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MKELAJLE_03460 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
MKELAJLE_03461 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
MKELAJLE_03462 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
MKELAJLE_03463 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
MKELAJLE_03464 4.7e-09 S YuzL-like protein
MKELAJLE_03465 2.2e-165 fadM E Proline dehydrogenase
MKELAJLE_03466 5.1e-40
MKELAJLE_03467 3.2e-53 yusN M Coat F domain
MKELAJLE_03468 5.4e-75 yusO K Iron dependent repressor, N-terminal DNA binding domain
MKELAJLE_03469 3.8e-293 yusP P Major facilitator superfamily
MKELAJLE_03470 8.4e-66 yusQ S Tautomerase enzyme
MKELAJLE_03471 2.5e-62 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MKELAJLE_03472 2.5e-50 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MKELAJLE_03473 2.7e-160 yusT K LysR substrate binding domain
MKELAJLE_03474 3.8e-47 yusU S Protein of unknown function (DUF2573)
MKELAJLE_03475 1e-153 yusV 3.6.3.34 HP ABC transporter
MKELAJLE_03476 5.6e-66 S YusW-like protein
MKELAJLE_03477 6.3e-258 pepF2 E COG1164 Oligoendopeptidase F
MKELAJLE_03478 3.9e-34 pepF2 E COG1164 Oligoendopeptidase F
MKELAJLE_03479 4.7e-154 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MKELAJLE_03480 1.2e-79 dps P Ferritin-like domain
MKELAJLE_03481 9.6e-237 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MKELAJLE_03482 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKELAJLE_03483 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
MKELAJLE_03484 4.3e-158 yuxN K Transcriptional regulator
MKELAJLE_03485 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MKELAJLE_03486 2.3e-24 S Protein of unknown function (DUF3970)
MKELAJLE_03487 2.2e-247 gerAA EG Spore germination protein
MKELAJLE_03488 9.1e-198 gerAB E Spore germination protein
MKELAJLE_03489 4.6e-189 gerAC S Spore germination B3/ GerAC like, C-terminal
MKELAJLE_03490 1.3e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKELAJLE_03491 5.5e-187 vraS 2.7.13.3 T Histidine kinase
MKELAJLE_03492 5.6e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
MKELAJLE_03493 9.3e-129 liaG S Putative adhesin
MKELAJLE_03494 2.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
MKELAJLE_03495 5.6e-62 liaI S membrane
MKELAJLE_03496 4.8e-227 yvqJ EGP Major facilitator Superfamily
MKELAJLE_03497 6.5e-102 yvqK 2.5.1.17 S Adenosyltransferase
MKELAJLE_03498 2.8e-249 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
MKELAJLE_03499 7.7e-186 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKELAJLE_03500 1.8e-170 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
MKELAJLE_03501 6.2e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MKELAJLE_03502 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
MKELAJLE_03503 0.0 T PhoQ Sensor
MKELAJLE_03504 3.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKELAJLE_03505 3.6e-22
MKELAJLE_03506 1.8e-96 yvrI K RNA polymerase
MKELAJLE_03507 2.4e-19 S YvrJ protein family
MKELAJLE_03508 7.3e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
MKELAJLE_03509 1.3e-64 yvrL S Regulatory protein YrvL
MKELAJLE_03510 1.8e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
MKELAJLE_03511 7.1e-124 macB V ABC transporter, ATP-binding protein
MKELAJLE_03512 4.8e-176 M Efflux transporter rnd family, mfp subunit
MKELAJLE_03513 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
MKELAJLE_03514 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKELAJLE_03515 9.3e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKELAJLE_03516 2.1e-179 fhuD P ABC transporter
MKELAJLE_03518 2.6e-237 yvsH E Arginine ornithine antiporter
MKELAJLE_03519 6.5e-16 S Small spore protein J (Spore_SspJ)
MKELAJLE_03520 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
MKELAJLE_03521 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MKELAJLE_03522 8e-171 yvgK P COG1910 Periplasmic molybdate-binding protein domain
MKELAJLE_03523 5.8e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
MKELAJLE_03524 4.7e-120 modB P COG4149 ABC-type molybdate transport system, permease component
MKELAJLE_03525 9.1e-158 yvgN S reductase
MKELAJLE_03526 5.4e-86 yvgO
MKELAJLE_03527 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
MKELAJLE_03528 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
MKELAJLE_03529 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MKELAJLE_03530 0.0 helD 3.6.4.12 L DNA helicase
MKELAJLE_03531 4.1e-107 yvgT S membrane
MKELAJLE_03532 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
MKELAJLE_03533 1.6e-104 bdbD O Thioredoxin
MKELAJLE_03534 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
MKELAJLE_03535 0.0 copA 3.6.3.54 P P-type ATPase
MKELAJLE_03536 1.5e-29 copZ P Copper resistance protein CopZ
MKELAJLE_03537 2.2e-48 csoR S transcriptional
MKELAJLE_03538 2.1e-199 yvaA 1.1.1.371 S Oxidoreductase
MKELAJLE_03539 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MKELAJLE_03540 0.0 yvaC S Fusaric acid resistance protein-like
MKELAJLE_03541 5.7e-73 yvaD S Family of unknown function (DUF5360)
MKELAJLE_03542 2.8e-55 yvaE P Small Multidrug Resistance protein
MKELAJLE_03543 4.1e-101 K Bacterial regulatory proteins, tetR family
MKELAJLE_03544 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MKELAJLE_03546 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MKELAJLE_03547 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MKELAJLE_03548 5.6e-143 est 3.1.1.1 S Carboxylesterase
MKELAJLE_03549 2.4e-23 secG U Preprotein translocase subunit SecG
MKELAJLE_03550 3.7e-153 yvaM S Serine aminopeptidase, S33
MKELAJLE_03551 7.5e-36 yvzC K Transcriptional
MKELAJLE_03552 4e-69 K transcriptional
MKELAJLE_03553 8e-70 yvaO K Cro/C1-type HTH DNA-binding domain
MKELAJLE_03554 2.2e-54 yodB K transcriptional
MKELAJLE_03555 4.2e-226 NT chemotaxis protein
MKELAJLE_03556 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
MKELAJLE_03557 1.1e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MKELAJLE_03558 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
MKELAJLE_03559 3e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MKELAJLE_03560 8.7e-61 yvbF K Belongs to the GbsR family
MKELAJLE_03561 7.9e-13 S Sporulation delaying protein SdpA
MKELAJLE_03562 7.6e-172
MKELAJLE_03563 4.4e-08
MKELAJLE_03564 3.3e-96 sdpI S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
MKELAJLE_03565 4.5e-45 sdpR K transcriptional
MKELAJLE_03566 8.7e-114 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
MKELAJLE_03567 2.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MKELAJLE_03568 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
MKELAJLE_03569 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MKELAJLE_03570 1.4e-98 yvbF K Belongs to the GbsR family
MKELAJLE_03571 6.4e-103 yvbG U UPF0056 membrane protein
MKELAJLE_03572 8.6e-113 yvbH S YvbH-like oligomerisation region
MKELAJLE_03573 4.2e-124 exoY M Membrane
MKELAJLE_03574 0.0 tcaA S response to antibiotic
MKELAJLE_03575 7.7e-82 yvbK 3.1.3.25 K acetyltransferase
MKELAJLE_03576 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MKELAJLE_03577 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
MKELAJLE_03578 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MKELAJLE_03579 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MKELAJLE_03580 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MKELAJLE_03581 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MKELAJLE_03582 1.6e-252 araE EGP Major facilitator Superfamily
MKELAJLE_03583 5.5e-203 araR K transcriptional
MKELAJLE_03584 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKELAJLE_03585 3.9e-159 yvbU K Transcriptional regulator
MKELAJLE_03586 8.5e-157 yvbV EG EamA-like transporter family
MKELAJLE_03587 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
MKELAJLE_03588 4.3e-197 yvbX S Glycosyl hydrolase
MKELAJLE_03589 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MKELAJLE_03590 1.2e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
MKELAJLE_03591 1.5e-137 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MKELAJLE_03592 2.6e-106 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKELAJLE_03593 8.9e-201 desK 2.7.13.3 T Histidine kinase
MKELAJLE_03594 6.2e-134 yvfS V COG0842 ABC-type multidrug transport system, permease component
MKELAJLE_03595 3e-162 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
MKELAJLE_03596 2.6e-157 rsbQ S Alpha/beta hydrolase family
MKELAJLE_03597 1.4e-199 rsbU 3.1.3.3 T response regulator
MKELAJLE_03598 2.6e-252 galA 3.2.1.89 G arabinogalactan
MKELAJLE_03599 0.0 lacA 3.2.1.23 G beta-galactosidase
MKELAJLE_03600 3.2e-150 ganQ P transport
MKELAJLE_03601 1.3e-232 malC P COG1175 ABC-type sugar transport systems, permease components
MKELAJLE_03602 2.9e-232 cycB G COG2182 Maltose-binding periplasmic proteins domains
MKELAJLE_03603 1.8e-184 lacR K Transcriptional regulator
MKELAJLE_03604 1e-112 yvfI K COG2186 Transcriptional regulators
MKELAJLE_03605 1.4e-309 yvfH C L-lactate permease
MKELAJLE_03606 6.5e-243 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MKELAJLE_03607 1e-31 yvfG S YvfG protein
MKELAJLE_03608 5.8e-188 yvfF GM Exopolysaccharide biosynthesis protein
MKELAJLE_03609 1.2e-224 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
MKELAJLE_03610 2.2e-58 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
MKELAJLE_03611 2.6e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MKELAJLE_03612 8.9e-260 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MKELAJLE_03613 1.9e-197 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
MKELAJLE_03614 3.6e-207 epsI GM pyruvyl transferase
MKELAJLE_03615 3.6e-196 epsH GT2 S Glycosyltransferase like family 2
MKELAJLE_03616 4.8e-207 epsG S EpsG family
MKELAJLE_03617 5.3e-220 epsF GT4 M Glycosyl transferases group 1
MKELAJLE_03618 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MKELAJLE_03619 2e-224 epsD GT4 M Glycosyl transferase 4-like
MKELAJLE_03620 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
MKELAJLE_03621 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
MKELAJLE_03622 4e-122 ywqC M biosynthesis protein
MKELAJLE_03623 5.7e-77 slr K transcriptional
MKELAJLE_03624 4.8e-287 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
MKELAJLE_03626 4.6e-93 padC Q Phenolic acid decarboxylase
MKELAJLE_03627 1.3e-48 MA20_18690 S Protein of unknown function (DUF3237)
MKELAJLE_03628 3.1e-127 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
MKELAJLE_03629 9.6e-266 pbpE V Beta-lactamase
MKELAJLE_03630 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
MKELAJLE_03631 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
MKELAJLE_03632 1.8e-295 yveA E amino acid
MKELAJLE_03633 2.6e-106 yvdT K Transcriptional regulator
MKELAJLE_03634 6.7e-51 ykkC P Small Multidrug Resistance protein
MKELAJLE_03635 4.1e-50 sugE P Small Multidrug Resistance protein
MKELAJLE_03636 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
MKELAJLE_03637 8.4e-270 ygaK C COG0277 FAD FMN-containing dehydrogenases
MKELAJLE_03638 1.5e-183 S Patatin-like phospholipase
MKELAJLE_03640 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MKELAJLE_03641 1.3e-122 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
MKELAJLE_03642 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
MKELAJLE_03643 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
MKELAJLE_03644 1.2e-158 malA S Protein of unknown function (DUF1189)
MKELAJLE_03645 7.8e-149 malD P transport
MKELAJLE_03646 5.3e-245 malC P COG1175 ABC-type sugar transport systems, permease components
MKELAJLE_03647 1.3e-235 mdxE G COG2182 Maltose-binding periplasmic proteins domains
MKELAJLE_03648 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
MKELAJLE_03649 3.6e-174 yvdE K Transcriptional regulator
MKELAJLE_03650 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
MKELAJLE_03651 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
MKELAJLE_03652 2.1e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
MKELAJLE_03653 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
MKELAJLE_03654 1.3e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKELAJLE_03655 0.0 yxdM V ABC transporter (permease)
MKELAJLE_03656 5.6e-141 yvcR V ABC transporter, ATP-binding protein
MKELAJLE_03657 2.3e-198 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
MKELAJLE_03658 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKELAJLE_03659 1.8e-33
MKELAJLE_03660 8.6e-147 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
MKELAJLE_03661 1.6e-36 crh G Phosphocarrier protein Chr
MKELAJLE_03662 1.4e-170 whiA K May be required for sporulation
MKELAJLE_03663 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MKELAJLE_03664 5.7e-166 rapZ S Displays ATPase and GTPase activities
MKELAJLE_03665 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MKELAJLE_03666 1.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MKELAJLE_03667 1.4e-102 usp CBM50 M protein conserved in bacteria
MKELAJLE_03668 2.4e-278 S COG0457 FOG TPR repeat
MKELAJLE_03669 0.0 msbA2 3.6.3.44 V ABC transporter
MKELAJLE_03671 0.0
MKELAJLE_03672 4.6e-121
MKELAJLE_03673 8e-114 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
MKELAJLE_03674 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MKELAJLE_03675 3.1e-133 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MKELAJLE_03676 1.7e-116 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MKELAJLE_03677 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
MKELAJLE_03678 6.6e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MKELAJLE_03679 1.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MKELAJLE_03680 4.8e-221 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MKELAJLE_03681 4.5e-140 yvpB NU protein conserved in bacteria
MKELAJLE_03682 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
MKELAJLE_03683 3e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
MKELAJLE_03684 1.3e-119 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MKELAJLE_03685 1.5e-164 yvoD P COG0370 Fe2 transport system protein B
MKELAJLE_03686 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MKELAJLE_03687 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MKELAJLE_03688 6.8e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MKELAJLE_03689 8.9e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MKELAJLE_03690 3.6e-134 yvoA K transcriptional
MKELAJLE_03691 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
MKELAJLE_03692 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
MKELAJLE_03693 8.2e-232 cypX 1.14.15.13 C Cytochrome P450
MKELAJLE_03694 1.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
MKELAJLE_03695 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
MKELAJLE_03696 2.7e-203 yvmA EGP Major facilitator Superfamily
MKELAJLE_03697 1.2e-50 yvlD S Membrane
MKELAJLE_03698 2.6e-26 pspB KT PspC domain
MKELAJLE_03699 3.4e-168 yvlB S Putative adhesin
MKELAJLE_03700 8e-49 yvlA
MKELAJLE_03701 6.7e-34 yvkN
MKELAJLE_03702 2.9e-79 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MKELAJLE_03703 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MKELAJLE_03704 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MKELAJLE_03705 1.2e-30 csbA S protein conserved in bacteria
MKELAJLE_03706 0.0 yvkC 2.7.9.2 GT Phosphotransferase
MKELAJLE_03707 7e-101 yvkB K Transcriptional regulator
MKELAJLE_03708 7.9e-228 yvkA EGP Major facilitator Superfamily
MKELAJLE_03709 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MKELAJLE_03710 5.3e-56 swrA S Swarming motility protein
MKELAJLE_03711 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
MKELAJLE_03712 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MKELAJLE_03713 1.6e-123 ftsE D cell division ATP-binding protein FtsE
MKELAJLE_03714 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
MKELAJLE_03715 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
MKELAJLE_03716 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MKELAJLE_03717 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MKELAJLE_03718 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MKELAJLE_03719 2.8e-66
MKELAJLE_03720 1.9e-08 fliT S bacterial-type flagellum organization
MKELAJLE_03721 2.9e-69 fliS N flagellar protein FliS
MKELAJLE_03722 1.3e-266 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MKELAJLE_03723 6.1e-57 flaG N flagellar protein FlaG
MKELAJLE_03724 1.9e-156 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MKELAJLE_03725 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MKELAJLE_03726 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MKELAJLE_03727 2.6e-50 yviE
MKELAJLE_03728 1.1e-156 flgL N Belongs to the bacterial flagellin family
MKELAJLE_03729 1.2e-264 flgK N flagellar hook-associated protein
MKELAJLE_03730 2.4e-78 flgN NOU FlgN protein
MKELAJLE_03731 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
MKELAJLE_03732 7e-74 yvyF S flagellar protein
MKELAJLE_03733 2.7e-129 comFC S Phosphoribosyl transferase domain
MKELAJLE_03734 5.7e-46 comFB S Late competence development protein ComFB
MKELAJLE_03735 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MKELAJLE_03736 7.3e-155 degV S protein conserved in bacteria
MKELAJLE_03737 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKELAJLE_03738 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MKELAJLE_03739 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
MKELAJLE_03740 6e-163 yvhJ K Transcriptional regulator
MKELAJLE_03741 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
MKELAJLE_03742 4.4e-238 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
MKELAJLE_03743 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
MKELAJLE_03744 6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
MKELAJLE_03745 1.7e-263 tuaE M Teichuronic acid biosynthesis protein
MKELAJLE_03746 2.4e-259 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MKELAJLE_03747 7.4e-222 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
MKELAJLE_03748 3.3e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MKELAJLE_03749 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MKELAJLE_03750 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MKELAJLE_03751 0.0 lytB 3.5.1.28 D Stage II sporulation protein
MKELAJLE_03752 6e-38
MKELAJLE_03753 6.1e-163 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MKELAJLE_03754 8.2e-218 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MKELAJLE_03755 9e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MKELAJLE_03756 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MKELAJLE_03757 8.1e-257 ggaA M Glycosyltransferase like family 2
MKELAJLE_03759 1.6e-100 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MKELAJLE_03760 1.8e-279 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MKELAJLE_03761 1.1e-150 tagG GM Transport permease protein
MKELAJLE_03762 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MKELAJLE_03763 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
MKELAJLE_03764 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
MKELAJLE_03765 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MKELAJLE_03766 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MKELAJLE_03767 1.2e-260
MKELAJLE_03768 7.2e-217 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MKELAJLE_03769 7.1e-191 pmi 5.3.1.8 G mannose-6-phosphate isomerase
MKELAJLE_03770 3.5e-266 gerBA EG Spore germination protein
MKELAJLE_03771 7.5e-200 gerBB E Spore germination protein
MKELAJLE_03772 7.6e-216 gerAC S Spore germination protein
MKELAJLE_03773 1.9e-248 ywtG EGP Major facilitator Superfamily
MKELAJLE_03774 8.4e-171 ywtF K Transcriptional regulator
MKELAJLE_03775 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
MKELAJLE_03776 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MKELAJLE_03777 3.6e-21 ywtC
MKELAJLE_03778 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
MKELAJLE_03779 8.6e-70 pgsC S biosynthesis protein
MKELAJLE_03780 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
MKELAJLE_03781 1.9e-178 rbsR K transcriptional
MKELAJLE_03782 2.9e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MKELAJLE_03783 2.8e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MKELAJLE_03784 2.3e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MKELAJLE_03785 1.4e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
MKELAJLE_03786 4.4e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
MKELAJLE_03787 4.6e-94 batE T Sh3 type 3 domain protein
MKELAJLE_03788 3.6e-48 ywsA S Protein of unknown function (DUF3892)
MKELAJLE_03789 1.5e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
MKELAJLE_03790 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
MKELAJLE_03791 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MKELAJLE_03792 1.1e-169 alsR K LysR substrate binding domain
MKELAJLE_03793 1.9e-220 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MKELAJLE_03794 7.5e-126 ywrJ
MKELAJLE_03795 7.6e-131 cotB
MKELAJLE_03796 1.2e-210 cotH M Spore Coat
MKELAJLE_03797 3.7e-12
MKELAJLE_03798 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MKELAJLE_03799 2.9e-54 S Domain of unknown function (DUF4181)
MKELAJLE_03800 9.6e-310 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
MKELAJLE_03801 2.1e-82 ywrC K Transcriptional regulator
MKELAJLE_03802 2.4e-104 ywrB P Chromate transporter
MKELAJLE_03803 6.9e-90 ywrA P COG2059 Chromate transport protein ChrA
MKELAJLE_03805 2.7e-102 ywqN S NAD(P)H-dependent
MKELAJLE_03806 2.9e-162 K Transcriptional regulator
MKELAJLE_03807 4.5e-137 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
MKELAJLE_03808 1.7e-52 S MORN repeat variant
MKELAJLE_03809 0.0 ywqJ L nucleic acid phosphodiester bond hydrolysis
MKELAJLE_03810 1.3e-38 ywqI S Family of unknown function (DUF5344)
MKELAJLE_03811 3.3e-15 S Domain of unknown function (DUF5082)
MKELAJLE_03812 3.4e-154 ywqG S Domain of unknown function (DUF1963)
MKELAJLE_03813 3e-248 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MKELAJLE_03814 1.4e-141 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
MKELAJLE_03815 1.1e-119 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
MKELAJLE_03816 2e-116 ywqC M biosynthesis protein
MKELAJLE_03817 1.2e-17
MKELAJLE_03818 3.8e-309 ywqB S SWIM zinc finger
MKELAJLE_03819 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
MKELAJLE_03820 3.6e-157 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
MKELAJLE_03821 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
MKELAJLE_03822 9.8e-58 ssbB L Single-stranded DNA-binding protein
MKELAJLE_03823 1.3e-66 ywpG
MKELAJLE_03824 1.1e-66 ywpF S YwpF-like protein
MKELAJLE_03825 8e-51 srtA 3.4.22.70 M Sortase family
MKELAJLE_03826 1.9e-153 ywpD T Histidine kinase
MKELAJLE_03827 1.5e-54 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MKELAJLE_03828 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MKELAJLE_03829 2.1e-199 S aspartate phosphatase
MKELAJLE_03830 1.5e-141 flhP N flagellar basal body
MKELAJLE_03831 6.9e-126 flhO N flagellar basal body
MKELAJLE_03832 3.5e-180 mbl D Rod shape-determining protein
MKELAJLE_03833 3e-44 spoIIID K Stage III sporulation protein D
MKELAJLE_03834 2.1e-70 ywoH K COG1846 Transcriptional regulators
MKELAJLE_03835 2.7e-211 ywoG EGP Major facilitator Superfamily
MKELAJLE_03836 1.2e-231 ywoF P Right handed beta helix region
MKELAJLE_03837 3e-281 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
MKELAJLE_03838 4.4e-242 ywoD EGP Major facilitator superfamily
MKELAJLE_03839 4e-104 phzA Q Isochorismatase family
MKELAJLE_03840 1.2e-77
MKELAJLE_03841 2.5e-225 amt P Ammonium transporter
MKELAJLE_03842 1.6e-58 nrgB K Belongs to the P(II) protein family
MKELAJLE_03843 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
MKELAJLE_03844 3.5e-73 ywnJ S VanZ like family
MKELAJLE_03845 5.5e-126 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
MKELAJLE_03846 6.4e-90 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
MKELAJLE_03847 2.7e-14 ywnC S Family of unknown function (DUF5362)
MKELAJLE_03848 2.2e-70 ywnF S Family of unknown function (DUF5392)
MKELAJLE_03849 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MKELAJLE_03850 4.1e-144 mta K transcriptional
MKELAJLE_03851 2.6e-59 ywnC S Family of unknown function (DUF5362)
MKELAJLE_03852 1.6e-114 ywnB S NAD(P)H-binding
MKELAJLE_03853 1.7e-64 ywnA K Transcriptional regulator
MKELAJLE_03854 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MKELAJLE_03855 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
MKELAJLE_03856 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
MKELAJLE_03858 3.8e-11 csbD K CsbD-like
MKELAJLE_03859 3e-84 ywmF S Peptidase M50
MKELAJLE_03860 1.3e-103 S response regulator aspartate phosphatase
MKELAJLE_03861 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MKELAJLE_03862 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MKELAJLE_03864 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
MKELAJLE_03865 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
MKELAJLE_03866 2e-178 spoIID D Stage II sporulation protein D
MKELAJLE_03867 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MKELAJLE_03868 1.6e-134 ywmB S TATA-box binding
MKELAJLE_03869 1.3e-32 ywzB S membrane
MKELAJLE_03870 4.3e-88 ywmA
MKELAJLE_03871 5.9e-54 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MKELAJLE_03872 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MKELAJLE_03873 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MKELAJLE_03874 6.9e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MKELAJLE_03875 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MKELAJLE_03876 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MKELAJLE_03877 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MKELAJLE_03878 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
MKELAJLE_03879 2.5e-62 atpI S ATP synthase
MKELAJLE_03880 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MKELAJLE_03881 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MKELAJLE_03882 7.2e-95 ywlG S Belongs to the UPF0340 family
MKELAJLE_03883 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
MKELAJLE_03884 1.7e-78 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MKELAJLE_03885 1.7e-91 mntP P Probably functions as a manganese efflux pump
MKELAJLE_03886 1.2e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MKELAJLE_03887 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
MKELAJLE_03888 6.1e-112 spoIIR S stage II sporulation protein R
MKELAJLE_03889 3.4e-56 ywlA S Uncharacterised protein family (UPF0715)
MKELAJLE_03891 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MKELAJLE_03892 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MKELAJLE_03893 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKELAJLE_03894 1.7e-91 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
MKELAJLE_03895 8.6e-160 ywkB S Membrane transport protein
MKELAJLE_03896 0.0 sfcA 1.1.1.38 C malic enzyme
MKELAJLE_03897 2.4e-104 tdk 2.7.1.21 F thymidine kinase
MKELAJLE_03898 1.1e-32 rpmE J Binds the 23S rRNA
MKELAJLE_03899 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MKELAJLE_03900 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
MKELAJLE_03901 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MKELAJLE_03902 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MKELAJLE_03903 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
MKELAJLE_03904 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
MKELAJLE_03905 2.4e-92 ywjG S Domain of unknown function (DUF2529)
MKELAJLE_03906 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MKELAJLE_03907 1.5e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MKELAJLE_03908 2.6e-211 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
MKELAJLE_03909 0.0 fadF C COG0247 Fe-S oxidoreductase
MKELAJLE_03910 2.3e-223 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MKELAJLE_03911 6.6e-184 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
MKELAJLE_03912 2.7e-42 ywjC
MKELAJLE_03913 4.8e-96 ywjB H RibD C-terminal domain
MKELAJLE_03914 0.0 ywjA V ABC transporter
MKELAJLE_03915 6.4e-287 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MKELAJLE_03916 1.8e-124 narI 1.7.5.1 C nitrate reductase, gamma
MKELAJLE_03917 2.4e-98 narJ 1.7.5.1 C nitrate reductase
MKELAJLE_03918 1e-297 narH 1.7.5.1 C Nitrate reductase, beta
MKELAJLE_03919 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MKELAJLE_03920 7e-86 arfM T cyclic nucleotide binding
MKELAJLE_03921 4.3e-140 ywiC S YwiC-like protein
MKELAJLE_03922 5.3e-130 fnr K helix_turn_helix, cAMP Regulatory protein
MKELAJLE_03923 9.8e-214 narK P COG2223 Nitrate nitrite transporter
MKELAJLE_03924 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MKELAJLE_03925 4.7e-73 ywiB S protein conserved in bacteria
MKELAJLE_03926 1e-07 S Bacteriocin subtilosin A
MKELAJLE_03927 2.6e-271 C Fe-S oxidoreductases
MKELAJLE_03929 3.3e-132 cbiO V ABC transporter
MKELAJLE_03930 3.1e-237 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
MKELAJLE_03931 2.7e-219 2.7.1.26, 2.7.7.2 L Peptidase, M16
MKELAJLE_03932 1.2e-249 L Peptidase, M16
MKELAJLE_03934 2.9e-249 ywhL CO amine dehydrogenase activity
MKELAJLE_03935 2.5e-205 ywhK CO amine dehydrogenase activity
MKELAJLE_03936 2.3e-79 S aspartate phosphatase
MKELAJLE_03938 1e-84 ywhH S Aminoacyl-tRNA editing domain
MKELAJLE_03939 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
MKELAJLE_03940 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MKELAJLE_03941 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MKELAJLE_03942 5.2e-95 ywhD S YwhD family
MKELAJLE_03943 5.1e-119 ywhC S Peptidase family M50
MKELAJLE_03944 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
MKELAJLE_03945 3.3e-71 ywhA K Transcriptional regulator
MKELAJLE_03946 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MKELAJLE_03948 2.6e-242 mmr U Major Facilitator Superfamily
MKELAJLE_03949 2.8e-79 yffB K Transcriptional regulator
MKELAJLE_03950 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
MKELAJLE_03951 1.8e-256 ywfO S COG1078 HD superfamily phosphohydrolases
MKELAJLE_03952 3.1e-36 ywzC S Belongs to the UPF0741 family
MKELAJLE_03953 1.6e-111 rsfA_1
MKELAJLE_03954 5.2e-159 ywfM EG EamA-like transporter family
MKELAJLE_03955 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MKELAJLE_03956 9.2e-164 cysL K Transcriptional regulator
MKELAJLE_03957 6.6e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
MKELAJLE_03958 1.1e-146 ywfI C May function as heme-dependent peroxidase
MKELAJLE_03959 4e-139 IQ Enoyl-(Acyl carrier protein) reductase
MKELAJLE_03960 2.7e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
MKELAJLE_03961 2.9e-210 bacE EGP Major facilitator Superfamily
MKELAJLE_03962 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
MKELAJLE_03963 1.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKELAJLE_03964 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
MKELAJLE_03965 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
MKELAJLE_03966 4.6e-206 ywfA EGP Major facilitator Superfamily
MKELAJLE_03967 4e-262 lysP E amino acid
MKELAJLE_03968 0.0 rocB E arginine degradation protein
MKELAJLE_03969 1.4e-297 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
MKELAJLE_03970 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
MKELAJLE_03971 1.8e-78
MKELAJLE_03972 3.5e-87 spsL 5.1.3.13 M Spore Coat
MKELAJLE_03973 5.3e-161 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MKELAJLE_03974 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MKELAJLE_03975 1.9e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MKELAJLE_03976 1.7e-190 spsG M Spore Coat
MKELAJLE_03977 9.7e-132 spsF M Spore Coat
MKELAJLE_03978 3.2e-214 spsE 2.5.1.56 M acid synthase
MKELAJLE_03979 4e-164 spsD 2.3.1.210 K Spore Coat
MKELAJLE_03980 1.6e-224 spsC E Belongs to the DegT DnrJ EryC1 family
MKELAJLE_03981 1.5e-269 spsB M Capsule polysaccharide biosynthesis protein
MKELAJLE_03982 2.8e-145 spsA M Spore Coat
MKELAJLE_03983 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MKELAJLE_03984 4.3e-59 ywdK S small membrane protein
MKELAJLE_03985 1.3e-238 ywdJ F Xanthine uracil
MKELAJLE_03986 7.7e-49 ywdI S Family of unknown function (DUF5327)
MKELAJLE_03987 5.9e-263 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
MKELAJLE_03988 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MKELAJLE_03989 1.1e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
MKELAJLE_03991 1.4e-113 ywdD
MKELAJLE_03992 1.3e-57 pex K Transcriptional regulator PadR-like family
MKELAJLE_03993 9.3e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MKELAJLE_03994 2e-28 ywdA
MKELAJLE_03995 9.5e-296 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
MKELAJLE_03996 3.9e-254 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MKELAJLE_03997 1e-139 focA P Formate/nitrite transporter
MKELAJLE_03998 2.4e-150 sacT K transcriptional antiterminator
MKELAJLE_04000 0.0 vpr O Belongs to the peptidase S8 family
MKELAJLE_04001 5.1e-187 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKELAJLE_04002 7.2e-138 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
MKELAJLE_04003 2.9e-202 rodA D Belongs to the SEDS family
MKELAJLE_04004 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
MKELAJLE_04005 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
MKELAJLE_04006 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
MKELAJLE_04007 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MKELAJLE_04008 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MKELAJLE_04009 1e-35 ywzA S membrane
MKELAJLE_04010 3.7e-306 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MKELAJLE_04011 6.2e-229 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MKELAJLE_04012 9.5e-60 gtcA S GtrA-like protein
MKELAJLE_04013 2.2e-122 ywcC K transcriptional regulator
MKELAJLE_04015 9.8e-49 ywcB S Protein of unknown function, DUF485
MKELAJLE_04016 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MKELAJLE_04017 1.9e-112 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
MKELAJLE_04018 2.6e-225 ywbN P Dyp-type peroxidase family protein
MKELAJLE_04019 2e-187 ycdO P periplasmic lipoprotein involved in iron transport
MKELAJLE_04020 8.2e-255 P COG0672 High-affinity Fe2 Pb2 permease
MKELAJLE_04021 4.1e-116 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MKELAJLE_04022 2.8e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MKELAJLE_04023 4.3e-153 ywbI K Transcriptional regulator
MKELAJLE_04024 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
MKELAJLE_04025 2.3e-111 ywbG M effector of murein hydrolase
MKELAJLE_04026 1.9e-209 ywbF EGP Major facilitator Superfamily
MKELAJLE_04027 1.2e-28 ywbE S Uncharacterized conserved protein (DUF2196)
MKELAJLE_04028 8.9e-223 ywbD 2.1.1.191 J Methyltransferase
MKELAJLE_04029 4.4e-67 ywbC 4.4.1.5 E glyoxalase
MKELAJLE_04030 1.8e-127 ywbB S Protein of unknown function (DUF2711)
MKELAJLE_04031 5.8e-247 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKELAJLE_04032 1.6e-277 epr 3.4.21.62 O Belongs to the peptidase S8 family
MKELAJLE_04033 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MKELAJLE_04034 4e-153 sacY K transcriptional antiterminator
MKELAJLE_04035 7e-169 gspA M General stress
MKELAJLE_04036 1.7e-128 ywaF S Integral membrane protein
MKELAJLE_04037 8.1e-88 ywaE K Transcriptional regulator
MKELAJLE_04038 4.4e-233 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MKELAJLE_04039 1.4e-251 ywaD 3.4.11.10, 3.4.11.6 S PA domain
MKELAJLE_04040 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
MKELAJLE_04041 5.4e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
MKELAJLE_04042 5e-14 S D-Ala-teichoic acid biosynthesis protein
MKELAJLE_04043 7.9e-293 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKELAJLE_04044 1.2e-232 dltB M membrane protein involved in D-alanine export
MKELAJLE_04045 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKELAJLE_04046 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MKELAJLE_04047 6.6e-139 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
MKELAJLE_04048 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MKELAJLE_04049 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MKELAJLE_04050 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
MKELAJLE_04051 7.4e-250 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKELAJLE_04052 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
MKELAJLE_04053 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
MKELAJLE_04054 1.1e-19 yxzF
MKELAJLE_04055 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
MKELAJLE_04056 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
MKELAJLE_04057 2.1e-216 yxlH EGP Major facilitator Superfamily
MKELAJLE_04058 1.8e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MKELAJLE_04059 1.5e-166 yxlF V ABC transporter, ATP-binding protein
MKELAJLE_04060 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
MKELAJLE_04061 1.2e-31
MKELAJLE_04062 3.9e-48 yxlC S Family of unknown function (DUF5345)
MKELAJLE_04063 4.7e-91 sigY K Belongs to the sigma-70 factor family. ECF subfamily
MKELAJLE_04064 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
MKELAJLE_04065 8e-162 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MKELAJLE_04066 0.0 cydD V ATP-binding protein
MKELAJLE_04067 0.0 cydD V ATP-binding
MKELAJLE_04068 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
MKELAJLE_04069 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
MKELAJLE_04070 1.5e-229 cimH C COG3493 Na citrate symporter
MKELAJLE_04071 0.0 3.4.24.84 O Peptidase family M48
MKELAJLE_04073 3e-156 yxkH G Polysaccharide deacetylase
MKELAJLE_04074 5.9e-205 msmK P Belongs to the ABC transporter superfamily
MKELAJLE_04075 4.8e-165 lrp QT PucR C-terminal helix-turn-helix domain
MKELAJLE_04076 2.5e-275 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MKELAJLE_04077 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MKELAJLE_04078 4.1e-73 yxkC S Domain of unknown function (DUF4352)
MKELAJLE_04079 4.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MKELAJLE_04080 1.3e-95 yxkA S Phosphatidylethanolamine-binding protein
MKELAJLE_04081 1.9e-166 yxjO K LysR substrate binding domain
MKELAJLE_04082 2.4e-78 S Protein of unknown function (DUF1453)
MKELAJLE_04083 1.5e-193 yxjM T Signal transduction histidine kinase
MKELAJLE_04084 8.9e-116 K helix_turn_helix, Lux Regulon
MKELAJLE_04085 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MKELAJLE_04088 1e-87 yxjI S LURP-one-related
MKELAJLE_04089 5.5e-222 yxjG 2.1.1.14 E Methionine synthase
MKELAJLE_04090 1e-220 yxjG 2.1.1.14 E Methionine synthase
MKELAJLE_04091 1.3e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MKELAJLE_04092 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MKELAJLE_04093 1.4e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MKELAJLE_04094 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
MKELAJLE_04095 3.1e-161 rlmA 2.1.1.187 Q Methyltransferase domain
MKELAJLE_04096 1.9e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MKELAJLE_04097 1.2e-22 T Domain of unknown function (DUF4163)
MKELAJLE_04098 2.7e-48 yxiS
MKELAJLE_04099 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
MKELAJLE_04100 6.6e-224 citH C Citrate transporter
MKELAJLE_04101 5e-144 exoK GH16 M licheninase activity
MKELAJLE_04102 8.3e-151 licT K transcriptional antiterminator
MKELAJLE_04103 6.6e-114
MKELAJLE_04104 3e-232 yxiO S COG2270 Permeases of the major facilitator superfamily
MKELAJLE_04105 1e-265 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
MKELAJLE_04106 7.5e-219 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
MKELAJLE_04109 1.6e-48 yxiJ S YxiJ-like protein
MKELAJLE_04110 1.2e-96 yxiI S Protein of unknown function (DUF2716)
MKELAJLE_04111 3.8e-81
MKELAJLE_04112 4.9e-46
MKELAJLE_04113 3.7e-75 yxiG
MKELAJLE_04114 6.4e-63
MKELAJLE_04115 1.7e-84
MKELAJLE_04116 1.5e-71 yxxG
MKELAJLE_04117 0.0 wapA M COG3209 Rhs family protein
MKELAJLE_04118 2.9e-168 yxxF EG EamA-like transporter family
MKELAJLE_04119 1.1e-72 yxiE T Belongs to the universal stress protein A family
MKELAJLE_04120 6.6e-281 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MKELAJLE_04121 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MKELAJLE_04122 3.6e-51
MKELAJLE_04123 2.2e-78 S SMI1 / KNR4 family
MKELAJLE_04124 0.0 S nuclease activity
MKELAJLE_04125 3.6e-39 yxiC S Family of unknown function (DUF5344)
MKELAJLE_04126 2.1e-21 S Domain of unknown function (DUF5082)
MKELAJLE_04127 6.3e-284 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
MKELAJLE_04128 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
MKELAJLE_04129 2.3e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
MKELAJLE_04130 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MKELAJLE_04131 1.2e-238 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
MKELAJLE_04132 8e-182 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
MKELAJLE_04133 6.1e-252 lysP E amino acid
MKELAJLE_04134 4.2e-234 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
MKELAJLE_04135 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MKELAJLE_04136 7e-116 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MKELAJLE_04137 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MKELAJLE_04138 3e-153 yxxB S Domain of Unknown Function (DUF1206)
MKELAJLE_04139 6.8e-201 eutH E Ethanolamine utilisation protein, EutH
MKELAJLE_04140 2e-255 yxeQ S MmgE/PrpD family
MKELAJLE_04141 3.8e-215 yxeP 3.5.1.47 E hydrolase activity
MKELAJLE_04142 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
MKELAJLE_04143 5.4e-108 yxeN P COG0765 ABC-type amino acid transport system, permease component
MKELAJLE_04144 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
MKELAJLE_04145 7.3e-94 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKELAJLE_04146 2.2e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKELAJLE_04148 8.8e-192 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
MKELAJLE_04149 6.2e-151 yidA S hydrolases of the HAD superfamily
MKELAJLE_04152 1.3e-20 yxeE
MKELAJLE_04153 1.9e-16 yxeD
MKELAJLE_04154 8.5e-69
MKELAJLE_04155 6e-177 fhuD P ABC transporter
MKELAJLE_04156 1.5e-58 yxeA S Protein of unknown function (DUF1093)
MKELAJLE_04157 0.0 yxdM V ABC transporter (permease)
MKELAJLE_04158 9.4e-141 yxdL V ABC transporter, ATP-binding protein
MKELAJLE_04159 1.3e-182 T PhoQ Sensor
MKELAJLE_04160 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKELAJLE_04161 5.4e-161 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
MKELAJLE_04162 1.9e-139 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
MKELAJLE_04163 2.3e-167 iolH G Xylose isomerase-like TIM barrel
MKELAJLE_04164 2.8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MKELAJLE_04165 1.3e-235 iolF EGP Major facilitator Superfamily
MKELAJLE_04166 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MKELAJLE_04167 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MKELAJLE_04168 2.9e-179 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MKELAJLE_04169 1.1e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MKELAJLE_04170 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MKELAJLE_04171 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
MKELAJLE_04172 3.7e-176 iolS C Aldo keto reductase
MKELAJLE_04174 8.3e-48 yxcD S Protein of unknown function (DUF2653)
MKELAJLE_04175 2.3e-246 csbC EGP Major facilitator Superfamily
MKELAJLE_04176 0.0 htpG O Molecular chaperone. Has ATPase activity
MKELAJLE_04178 5.7e-152 IQ Enoyl-(Acyl carrier protein) reductase
MKELAJLE_04179 2.2e-215 yxbF K Bacterial regulatory proteins, tetR family
MKELAJLE_04180 1.4e-248 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
MKELAJLE_04181 1.6e-85 yxbD 3.2.2.20 K Acetyltransferase (GNAT) domain
MKELAJLE_04182 2.2e-187 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
MKELAJLE_04183 3.3e-127 yxbB Q Met-10+ like-protein
MKELAJLE_04184 4.9e-44 S Coenzyme PQQ synthesis protein D (PqqD)
MKELAJLE_04185 1.1e-86 yxnB
MKELAJLE_04186 0.0 asnB 6.3.5.4 E Asparagine synthase
MKELAJLE_04187 7.6e-214 yxaM U MFS_1 like family
MKELAJLE_04188 6.8e-93 S PQQ-like domain
MKELAJLE_04189 3.5e-65 S Family of unknown function (DUF5391)
MKELAJLE_04190 1.1e-75 yxaI S membrane protein domain
MKELAJLE_04191 1.4e-228 P Protein of unknown function (DUF418)
MKELAJLE_04192 1.5e-199 yxaG 1.13.11.24 S AraC-like ligand binding domain
MKELAJLE_04193 7.1e-101 yxaF K Transcriptional regulator
MKELAJLE_04194 2.3e-201 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MKELAJLE_04195 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
MKELAJLE_04196 5.2e-50 S LrgA family
MKELAJLE_04197 2.6e-118 yxaC M effector of murein hydrolase
MKELAJLE_04198 1.3e-193 yxaB GM Polysaccharide pyruvyl transferase
MKELAJLE_04199 7e-209 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MKELAJLE_04200 7.3e-127 gntR K transcriptional
MKELAJLE_04201 4.6e-304 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
MKELAJLE_04202 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
MKELAJLE_04203 3.8e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MKELAJLE_04204 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
MKELAJLE_04205 3.8e-287 ahpF O Alkyl hydroperoxide reductase
MKELAJLE_04206 6.4e-292 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MKELAJLE_04207 2.5e-19 bglF G phosphotransferase system
MKELAJLE_04208 1.3e-128 yydK K Transcriptional regulator
MKELAJLE_04209 7.6e-13
MKELAJLE_04210 3.3e-119 S ABC-2 family transporter protein
MKELAJLE_04211 1.8e-110 prrC P ABC transporter
MKELAJLE_04212 8.4e-134 yydH O Peptidase M50
MKELAJLE_04213 7.7e-185 S Radical SAM superfamily
MKELAJLE_04214 8e-12
MKELAJLE_04215 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
MKELAJLE_04216 0.0 S Uncharacterised protein conserved in bacteria (DUF2326)
MKELAJLE_04217 3.5e-65
MKELAJLE_04218 7.3e-280 S Calcineurin-like phosphoesterase
MKELAJLE_04219 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MKELAJLE_04220 1.1e-09 S YyzF-like protein
MKELAJLE_04221 4.2e-71
MKELAJLE_04222 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MKELAJLE_04224 2.1e-33 yycQ S Protein of unknown function (DUF2651)
MKELAJLE_04225 1.6e-221 yycP
MKELAJLE_04226 5.8e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MKELAJLE_04227 3.1e-86 yycN 2.3.1.128 K Acetyltransferase
MKELAJLE_04228 5e-188 S aspartate phosphatase
MKELAJLE_04230 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
MKELAJLE_04231 9.7e-261 rocE E amino acid
MKELAJLE_04232 1.7e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
MKELAJLE_04233 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MKELAJLE_04234 8.4e-221 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MKELAJLE_04235 8.7e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MKELAJLE_04236 7.3e-155 yycI S protein conserved in bacteria
MKELAJLE_04237 3.6e-260 yycH S protein conserved in bacteria
MKELAJLE_04238 0.0 vicK 2.7.13.3 T Histidine kinase
MKELAJLE_04239 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKELAJLE_04244 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MKELAJLE_04245 8e-78 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKELAJLE_04246 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MKELAJLE_04247 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
MKELAJLE_04249 1.9e-15 yycC K YycC-like protein
MKELAJLE_04250 8.4e-221 yeaN P COG2807 Cyanate permease
MKELAJLE_04251 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MKELAJLE_04252 2.2e-73 rplI J binds to the 23S rRNA
MKELAJLE_04253 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MKELAJLE_04254 2.9e-160 yybS S membrane
MKELAJLE_04256 3.9e-84 cotF M Spore coat protein
MKELAJLE_04257 1.4e-68 ydeP3 K Transcriptional regulator
MKELAJLE_04258 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
MKELAJLE_04259 1.3e-70
MKELAJLE_04261 2.3e-240 yybO G COG0477 Permeases of the major facilitator superfamily
MKELAJLE_04262 1e-16
MKELAJLE_04263 1.3e-78 yybN S Protein of unknown function (DUF2712)
MKELAJLE_04264 4.1e-125
MKELAJLE_04265 9e-122
MKELAJLE_04266 2e-127 S Protein of unknown function (DUF2705)
MKELAJLE_04267 2.6e-115 V ATPases associated with a variety of cellular activities
MKELAJLE_04268 6.2e-132
MKELAJLE_04269 5.9e-67 yybH S SnoaL-like domain
MKELAJLE_04270 3e-124 yybG S Pentapeptide repeat-containing protein
MKELAJLE_04271 3.2e-220 ynfM EGP Major facilitator Superfamily
MKELAJLE_04272 2.1e-165 yybE K Transcriptional regulator
MKELAJLE_04273 2e-79 yjcF S Acetyltransferase (GNAT) domain
MKELAJLE_04274 2.7e-77 yybC
MKELAJLE_04275 3e-127 S Metallo-beta-lactamase superfamily
MKELAJLE_04276 5.6e-77 yybA 2.3.1.57 K transcriptional
MKELAJLE_04277 5.9e-79 yjcF S Acetyltransferase (GNAT) domain
MKELAJLE_04278 1.5e-101 yyaS S Membrane
MKELAJLE_04279 5.4e-100 yyaR K Acetyltransferase (GNAT) domain
MKELAJLE_04280 5.4e-67 yyaQ S YjbR
MKELAJLE_04281 1.7e-107 yyaP 1.5.1.3 H RibD C-terminal domain
MKELAJLE_04282 1.7e-249 tetL EGP Major facilitator Superfamily
MKELAJLE_04283 9.7e-44 yyaL O Highly conserved protein containing a thioredoxin domain
MKELAJLE_04284 5.1e-61 yyaN K MerR HTH family regulatory protein
MKELAJLE_04285 3.3e-161 yyaM EG EamA-like transporter family
MKELAJLE_04286 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
MKELAJLE_04287 9.5e-169 yyaK S CAAX protease self-immunity
MKELAJLE_04288 8.5e-246 EGP Major facilitator superfamily
MKELAJLE_04289 5.1e-96 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
MKELAJLE_04290 4e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKELAJLE_04291 3.3e-180 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
MKELAJLE_04292 8.1e-145 xth 3.1.11.2 L exodeoxyribonuclease III
MKELAJLE_04293 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MKELAJLE_04294 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MKELAJLE_04295 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
MKELAJLE_04296 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MKELAJLE_04297 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MKELAJLE_04298 2.3e-33 yyzM S protein conserved in bacteria
MKELAJLE_04299 8.1e-177 yyaD S Membrane
MKELAJLE_04300 1.6e-111 yyaC S Sporulation protein YyaC
MKELAJLE_04301 2.1e-149 spo0J K Belongs to the ParB family
MKELAJLE_04302 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
MKELAJLE_04303 1.5e-74 S Bacterial PH domain
MKELAJLE_04304 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MKELAJLE_04305 2.2e-131 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MKELAJLE_04306 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MKELAJLE_04307 3.1e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MKELAJLE_04308 6.5e-108 jag S single-stranded nucleic acid binding R3H
MKELAJLE_04309 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MKELAJLE_04310 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MKELAJLE_04311 7e-148 S DNA gyrase/topoisomerase IV, subunit A
MKELAJLE_04312 3.4e-57 traC L Domain of unknown function (DUF1738)
MKELAJLE_04318 5.4e-13 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
MKELAJLE_04320 6e-128
MKELAJLE_04321 1.5e-20 L COG3666 Transposase and inactivated derivatives
MKELAJLE_04322 2.7e-61
MKELAJLE_04324 1.5e-63 S Immunity protein 70
MKELAJLE_04325 4.6e-174 A Pre-toxin TG
MKELAJLE_04326 1.2e-97 S Phage integrase family
MKELAJLE_04327 4.4e-106 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 CBM50 M Glycosyl hydrolases family 25
MKELAJLE_04328 4.3e-09 S SPP1 phage holin
MKELAJLE_04331 3e-12
MKELAJLE_04332 4.6e-76 S N-acetylmuramoyl-L-alanine amidase activity
MKELAJLE_04333 1.1e-23
MKELAJLE_04334 2.4e-147 S Phage minor structural protein
MKELAJLE_04335 1e-176 S Phage tail protein
MKELAJLE_04336 2.3e-174 D Phage tail tape measure protein
MKELAJLE_04338 1.6e-40 S Phage tail tube protein
MKELAJLE_04339 2.5e-07
MKELAJLE_04340 7.4e-14 S Bacteriophage HK97-gp10, putative tail-component
MKELAJLE_04341 1.2e-10 S Phage head-tail joining protein
MKELAJLE_04342 1.4e-21 S DNA packaging
MKELAJLE_04344 6.8e-87 S Phage capsid family
MKELAJLE_04345 1.9e-55 S Caudovirus prohead serine protease
MKELAJLE_04346 1.6e-106 S Phage portal protein
MKELAJLE_04349 8.1e-29 S Phage terminase, small subunit
MKELAJLE_04352 1.9e-177 S response regulator aspartate phosphatase
MKELAJLE_04354 9.7e-83
MKELAJLE_04356 1.2e-68 lig 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP dependent DNA ligase domain
MKELAJLE_04357 1.6e-22 yocH 3.5.1.28 M 3D domain
MKELAJLE_04360 3.6e-73 L integrase family
MKELAJLE_04361 2.9e-52
MKELAJLE_04364 2e-41 XK27_03185 S Phosphoribosyl-ATP pyrophosphohydrolase
MKELAJLE_04365 8.1e-20
MKELAJLE_04367 1.5e-31 yxcD S Protein of unknown function (DUF2653)
MKELAJLE_04368 2e-07
MKELAJLE_04370 2.5e-34
MKELAJLE_04371 8.2e-48 F Nucleoside 2-deoxyribosyltransferase
MKELAJLE_04374 1.9e-64 S AAA domain
MKELAJLE_04375 3.3e-277 S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
MKELAJLE_04376 4.3e-104 S Ribonucleotide reductase, small chain
MKELAJLE_04377 1.5e-11 fld C Flavodoxin
MKELAJLE_04379 4e-39
MKELAJLE_04381 1.5e-24
MKELAJLE_04382 1.3e-15
MKELAJLE_04383 6.1e-110 S DNA helicase activity
MKELAJLE_04384 1e-89 S DNA primase activity
MKELAJLE_04386 1.4e-86 S exonuclease activity
MKELAJLE_04387 2.4e-15 K Transcriptional regulator
MKELAJLE_04388 2.3e-17 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase like
MKELAJLE_04390 1.3e-06 yfbR S HD containing hydrolase-like enzyme
MKELAJLE_04393 1.8e-46 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MKELAJLE_04395 4.4e-10 thyX 2.1.1.148 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant
MKELAJLE_04397 0.0 S Bacterial DNA polymerase III alpha subunit
MKELAJLE_04401 1.8e-21 2.7.4.8 F Guanylate kinase homologues.
MKELAJLE_04402 1.6e-17 S Endodeoxyribonuclease RusA
MKELAJLE_04408 9.1e-11 tdk 2.7.1.21 F Psort location Cytoplasmic, score
MKELAJLE_04410 4e-15 repA S Replication initiator protein A (RepA) N-terminus
MKELAJLE_04411 2.6e-184 S DNA gyrase B

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)