ORF_ID e_value Gene_name EC_number CAZy COGs Description
NLBNMKHF_00001 1.4e-69 L Transposase
NLBNMKHF_00002 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
NLBNMKHF_00003 1.9e-227 rodA D Belongs to the SEDS family
NLBNMKHF_00004 7.1e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NLBNMKHF_00005 1.2e-112 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
NLBNMKHF_00006 2.7e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NLBNMKHF_00007 9.7e-138 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NLBNMKHF_00008 5.2e-66 GnaT 2.5.1.16 K acetyltransferase
NLBNMKHF_00009 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
NLBNMKHF_00010 1.7e-93 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NLBNMKHF_00011 4.6e-182 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NLBNMKHF_00012 1.1e-124 dnaD
NLBNMKHF_00013 2.9e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NLBNMKHF_00014 1.8e-06 KT response to antibiotic
NLBNMKHF_00015 3.3e-234 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NLBNMKHF_00016 4.6e-29 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NLBNMKHF_00017 2.2e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NLBNMKHF_00018 2.2e-148 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NLBNMKHF_00019 2.8e-73 argR K Regulates arginine biosynthesis genes
NLBNMKHF_00020 1e-301 recN L May be involved in recombinational repair of damaged DNA
NLBNMKHF_00021 9.3e-150 DegV S DegV family
NLBNMKHF_00022 2.2e-162 ypmR E COG2755 Lysophospholipase L1 and related esterases
NLBNMKHF_00023 6.2e-97 ypmS S Protein conserved in bacteria
NLBNMKHF_00024 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NLBNMKHF_00026 6.2e-179 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
NLBNMKHF_00027 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NLBNMKHF_00028 4.9e-290 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NLBNMKHF_00029 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NLBNMKHF_00030 3.5e-37 ysdA L Membrane
NLBNMKHF_00031 2.1e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NLBNMKHF_00032 2.4e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NLBNMKHF_00033 0.0 dnaE 2.7.7.7 L DNA polymerase
NLBNMKHF_00034 3.6e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NLBNMKHF_00035 6e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NLBNMKHF_00036 4.8e-31 L COG1943 Transposase and inactivated derivatives
NLBNMKHF_00037 2.9e-18 S Domain of unknown function (DUF4649)
NLBNMKHF_00038 1.4e-176 XK27_08835 S ABC transporter substrate binding protein
NLBNMKHF_00039 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
NLBNMKHF_00040 3.1e-136 XK27_08845 S abc transporter atp-binding protein
NLBNMKHF_00041 7.8e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NLBNMKHF_00042 1.8e-147 estA CE1 S Esterase
NLBNMKHF_00043 1.6e-126 XK27_08875 O Zinc-dependent metalloprotease
NLBNMKHF_00044 1.1e-17 XK27_08880
NLBNMKHF_00045 1e-75 fld C Flavodoxin
NLBNMKHF_00046 3.6e-277 clcA P Chloride transporter, ClC family
NLBNMKHF_00047 4.7e-37 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
NLBNMKHF_00048 1e-213 XK27_05110 P Chloride transporter ClC family
NLBNMKHF_00049 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NLBNMKHF_00052 3.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
NLBNMKHF_00053 4.6e-163 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NLBNMKHF_00054 3.3e-86 ytsP 1.8.4.14 T GAF domain-containing protein
NLBNMKHF_00055 4.6e-302 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NLBNMKHF_00056 4.8e-171 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NLBNMKHF_00057 1.2e-211 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NLBNMKHF_00058 2.8e-134 fasA KT Response regulator of the LytR AlgR family
NLBNMKHF_00059 4.5e-244 fasC 2.7.13.3 T protein histidine kinase activity
NLBNMKHF_00060 7.1e-210 hpk9 2.7.13.3 T protein histidine kinase activity
NLBNMKHF_00061 3.7e-157 hpk9 2.7.13.3 T protein histidine kinase activity
NLBNMKHF_00062 6.7e-232 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
NLBNMKHF_00063 3.5e-274 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NLBNMKHF_00064 0.0 amiA E ABC transporter, substrate-binding protein, family 5
NLBNMKHF_00065 1.4e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NLBNMKHF_00066 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NLBNMKHF_00067 1.2e-50 S Protein of unknown function (DUF3397)
NLBNMKHF_00068 9.2e-89 cah 4.2.1.1 P Reversible hydration of carbon dioxide
NLBNMKHF_00069 3.1e-127 WQ51_05710 S Mitochondrial biogenesis AIM24
NLBNMKHF_00070 1.1e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NLBNMKHF_00071 3.3e-73 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
NLBNMKHF_00072 2e-79 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
NLBNMKHF_00073 6.3e-108 XK27_09620 S FMN reductase (NADPH) activity
NLBNMKHF_00074 7.9e-230 XK27_09615 C reductase
NLBNMKHF_00075 4.8e-140 fnt P Formate nitrite transporter
NLBNMKHF_00076 3.9e-96 XK27_08585 S Psort location CytoplasmicMembrane, score
NLBNMKHF_00077 3.7e-185 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NLBNMKHF_00078 6.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NLBNMKHF_00079 1.8e-116 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
NLBNMKHF_00080 1.6e-94 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NLBNMKHF_00081 6.7e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NLBNMKHF_00082 5.3e-58 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NLBNMKHF_00083 1.1e-133 S HAD hydrolase, family IA, variant
NLBNMKHF_00084 8.6e-156 rrmA 2.1.1.187 Q methyltransferase
NLBNMKHF_00088 6.6e-90 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NLBNMKHF_00089 6.6e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NLBNMKHF_00090 8.3e-37 yeeD O sulfur carrier activity
NLBNMKHF_00091 5.8e-186 yeeE S Sulphur transport
NLBNMKHF_00092 1.1e-112 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NLBNMKHF_00093 1e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NLBNMKHF_00094 2e-08 XK27_10305 S Domain of unknown function (DUF4651)
NLBNMKHF_00095 5.9e-202 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
NLBNMKHF_00096 9.7e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NLBNMKHF_00097 1.8e-100 S CAAX amino terminal protease family protein
NLBNMKHF_00099 7.3e-110 V CAAX protease self-immunity
NLBNMKHF_00100 8.8e-27 lanR K sequence-specific DNA binding
NLBNMKHF_00101 4.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NLBNMKHF_00102 3.2e-175 ytxK 2.1.1.72 L DNA methylase
NLBNMKHF_00103 2e-12 comGF U Putative Competence protein ComGF
NLBNMKHF_00104 4.5e-71 comGF U Competence protein ComGF
NLBNMKHF_00105 3.1e-15 NU Type II secretory pathway pseudopilin
NLBNMKHF_00106 6.4e-70 cglD NU Competence protein
NLBNMKHF_00107 2.2e-43 comGC U Required for transformation and DNA binding
NLBNMKHF_00108 4.1e-142 cglB U protein transport across the cell outer membrane
NLBNMKHF_00109 1.1e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NLBNMKHF_00110 2.9e-68 S cog cog4699
NLBNMKHF_00111 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NLBNMKHF_00112 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NLBNMKHF_00113 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NLBNMKHF_00114 4.2e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NLBNMKHF_00115 1.1e-116 L Transposase
NLBNMKHF_00116 3.3e-79 L Transposase
NLBNMKHF_00117 2e-97 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
NLBNMKHF_00118 1.1e-231 ytoI K transcriptional regulator containing CBS domains
NLBNMKHF_00119 1.1e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
NLBNMKHF_00120 3.7e-163 rbn E Belongs to the UPF0761 family
NLBNMKHF_00121 1.7e-85 ccl S cog cog4708
NLBNMKHF_00122 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NLBNMKHF_00123 4e-184 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NLBNMKHF_00124 4.8e-174 yfjR K regulation of single-species biofilm formation
NLBNMKHF_00126 8.3e-71 S QueT transporter
NLBNMKHF_00127 8.5e-156 xth 3.1.11.2 L exodeoxyribonuclease III
NLBNMKHF_00129 2.9e-17 yjdB S Domain of unknown function (DUF4767)
NLBNMKHF_00130 6.7e-167 tehB 2.1.1.265 PQ tellurite resistance protein tehb
NLBNMKHF_00131 2.4e-189 O protein import
NLBNMKHF_00132 2.1e-129 agrA KT phosphorelay signal transduction system
NLBNMKHF_00133 7.8e-198 2.7.13.3 T GHKL domain
NLBNMKHF_00135 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NLBNMKHF_00136 1.5e-36 ylqC L Belongs to the UPF0109 family
NLBNMKHF_00137 3.5e-233 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NLBNMKHF_00138 0.0 ydaO E amino acid
NLBNMKHF_00139 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
NLBNMKHF_00140 5e-145 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NLBNMKHF_00141 1.7e-289 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
NLBNMKHF_00142 4.5e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NLBNMKHF_00143 4.1e-81 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NLBNMKHF_00144 9.5e-169 murB 1.3.1.98 M cell wall formation
NLBNMKHF_00145 2.6e-211 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NLBNMKHF_00146 4.1e-139 potB P ABC-type spermidine putrescine transport system, permease component I
NLBNMKHF_00147 2.3e-131 potC P ABC-type spermidine putrescine transport system, permease component II
NLBNMKHF_00148 2.6e-205 potD P spermidine putrescine ABC transporter
NLBNMKHF_00149 1.9e-145 XK27_08050 O HflC and HflK could regulate a protease
NLBNMKHF_00150 1.8e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
NLBNMKHF_00151 2.6e-158 GK ROK family
NLBNMKHF_00152 1.9e-208 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NLBNMKHF_00153 1e-104 wecD M Acetyltransferase (GNAT) domain
NLBNMKHF_00154 7.4e-222 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NLBNMKHF_00155 7.8e-72 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
NLBNMKHF_00156 1e-57 arsC 1.20.4.1 P Belongs to the ArsC family
NLBNMKHF_00158 5e-186 femA 2.3.2.10, 2.3.2.16 V FemAB family
NLBNMKHF_00159 2.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NLBNMKHF_00160 9e-122 atpB C it plays a direct role in the translocation of protons across the membrane
NLBNMKHF_00161 1.6e-77 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NLBNMKHF_00162 1e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NLBNMKHF_00163 1e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NLBNMKHF_00164 4.8e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NLBNMKHF_00165 7.9e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NLBNMKHF_00166 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NLBNMKHF_00167 1.5e-215 ftsW D Belongs to the SEDS family
NLBNMKHF_00168 1.6e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NLBNMKHF_00169 1.5e-245 S Polysaccharide biosynthesis protein
NLBNMKHF_00170 0.0 M Polysaccharide biosynthesis protein
NLBNMKHF_00171 1.3e-204 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NLBNMKHF_00172 2.7e-171 S glycosyl transferase family 2
NLBNMKHF_00173 4e-85
NLBNMKHF_00174 4.4e-205 M glycosyl transferase group 1
NLBNMKHF_00175 2e-163 S Glycosyl transferase family 2
NLBNMKHF_00176 7.4e-160 licD M LICD family
NLBNMKHF_00177 1.7e-126 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NLBNMKHF_00178 4.8e-257 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
NLBNMKHF_00179 6.1e-113 cpsD D COG0489 ATPases involved in chromosome partitioning
NLBNMKHF_00180 7.2e-116 cps4C M biosynthesis protein
NLBNMKHF_00181 6.8e-133 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
NLBNMKHF_00182 2e-240 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
NLBNMKHF_00183 9.1e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
NLBNMKHF_00184 1.9e-272 pepV 3.5.1.18 E Dipeptidase
NLBNMKHF_00185 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NLBNMKHF_00186 1.9e-92 yybC
NLBNMKHF_00187 5.5e-83 XK27_03610 K Gnat family
NLBNMKHF_00188 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NLBNMKHF_00189 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NLBNMKHF_00190 5.6e-84 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NLBNMKHF_00191 1.6e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NLBNMKHF_00192 2.4e-17 M LysM domain
NLBNMKHF_00193 8.6e-87 ebsA S Family of unknown function (DUF5322)
NLBNMKHF_00194 1.5e-233 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NLBNMKHF_00195 0.0 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NLBNMKHF_00196 1.3e-96 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NLBNMKHF_00197 4.4e-225 G COG0457 FOG TPR repeat
NLBNMKHF_00198 4.3e-177 yubA S permease
NLBNMKHF_00199 1.9e-91 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
NLBNMKHF_00200 7.3e-164 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NLBNMKHF_00201 3.2e-124 ftsE D cell division ATP-binding protein FtsE
NLBNMKHF_00202 5.7e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NLBNMKHF_00203 5.1e-204 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NLBNMKHF_00204 1e-156 yjjH S Calcineurin-like phosphoesterase
NLBNMKHF_00205 3.1e-133 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NLBNMKHF_00206 0.0 pacL 3.6.3.8 P cation transport ATPase
NLBNMKHF_00207 4.5e-67 ywiB S Domain of unknown function (DUF1934)
NLBNMKHF_00208 4.4e-135 XK27_00120 2.4.2.3 F Phosphorylase superfamily
NLBNMKHF_00209 1.7e-159 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
NLBNMKHF_00210 2e-146 yidA S hydrolases of the HAD superfamily
NLBNMKHF_00211 4.1e-207 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
NLBNMKHF_00212 8.7e-57 S Protein of unknown function (DUF454)
NLBNMKHF_00213 1.3e-153 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
NLBNMKHF_00214 1e-235 vicK 2.7.13.3 T Histidine kinase
NLBNMKHF_00215 3.8e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NLBNMKHF_00216 4.6e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
NLBNMKHF_00217 2.1e-143 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
NLBNMKHF_00218 3.8e-238 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
NLBNMKHF_00219 5.2e-08 MU outer membrane autotransporter barrel domain protein
NLBNMKHF_00220 3.9e-158 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NLBNMKHF_00222 9e-75 XK27_03180 T universal stress protein
NLBNMKHF_00223 2.9e-237 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
NLBNMKHF_00224 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NLBNMKHF_00225 2e-100 pncA Q isochorismatase
NLBNMKHF_00226 2.9e-292 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NLBNMKHF_00227 1.4e-41 tagE 2.4.1.52 GT4 M transferase activity, transferring glycosyl groups
NLBNMKHF_00228 1.8e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NLBNMKHF_00229 7.7e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NLBNMKHF_00230 3e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NLBNMKHF_00231 9.3e-65
NLBNMKHF_00232 6.3e-152 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NLBNMKHF_00233 5.1e-98 yqeG S hydrolase of the HAD superfamily
NLBNMKHF_00234 1.7e-212 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NLBNMKHF_00235 1.9e-47 yhbY J RNA-binding protein
NLBNMKHF_00236 1.2e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NLBNMKHF_00237 9.2e-104 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
NLBNMKHF_00238 2.7e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NLBNMKHF_00239 8.4e-139 yqeM Q Methyltransferase domain protein
NLBNMKHF_00240 6.5e-113 S AAA ATPase domain
NLBNMKHF_00241 8.5e-196 ylbM S Belongs to the UPF0348 family
NLBNMKHF_00242 3.4e-39 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
NLBNMKHF_00243 1.6e-44 yoeB S Addiction module toxin, Txe YoeB family
NLBNMKHF_00245 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
NLBNMKHF_00247 2e-101
NLBNMKHF_00250 3.3e-09
NLBNMKHF_00251 1e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NLBNMKHF_00252 1.3e-131 ecsA V abc transporter atp-binding protein
NLBNMKHF_00253 4.9e-177 ecsB U Bacterial ABC transporter protein EcsB
NLBNMKHF_00254 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
NLBNMKHF_00255 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NLBNMKHF_00257 4.7e-224 ytfP S Flavoprotein
NLBNMKHF_00258 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NLBNMKHF_00259 8.2e-63 XK27_02560 S cog cog2151
NLBNMKHF_00260 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
NLBNMKHF_00261 6.4e-105 dnaQ 2.7.7.7 L DNA polymerase III
NLBNMKHF_00262 1.6e-126 K transcriptional regulator, MerR family
NLBNMKHF_00263 0.0 V ABC transporter (Permease
NLBNMKHF_00264 7.3e-124 V abc transporter atp-binding protein
NLBNMKHF_00266 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NLBNMKHF_00267 0.0 M Pilin isopeptide linkage domain protein
NLBNMKHF_00268 0.0 M Pilin isopeptide linkage domain protein
NLBNMKHF_00269 0.0 zmpB M signal peptide protein, YSIRK family
NLBNMKHF_00270 0.0 GM domain, Protein
NLBNMKHF_00271 9e-223 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NLBNMKHF_00272 0.0 sbcC L ATPase involved in DNA repair
NLBNMKHF_00273 6.9e-09
NLBNMKHF_00275 3.4e-155 cat 2.3.1.28 S acetyltransferase'
NLBNMKHF_00276 0.0 M family 8
NLBNMKHF_00277 1e-146 epsH S acetyltransferase'
NLBNMKHF_00278 9.9e-238 M Glycosyltransferase, family 8
NLBNMKHF_00279 7.1e-286 tagE 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NLBNMKHF_00280 5.8e-193 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NLBNMKHF_00281 3.3e-186 nss M transferase activity, transferring glycosyl groups
NLBNMKHF_00282 1.9e-236 M Glycosyltransferase, family 8
NLBNMKHF_00283 2.5e-166 cpsJ M Glycosyltransferase group 2 family protein
NLBNMKHF_00284 0.0 M cog cog1442
NLBNMKHF_00285 5.8e-241 M family 8
NLBNMKHF_00286 2.3e-165 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
NLBNMKHF_00287 9.5e-310 asp1 S Accessory Sec system protein Asp1
NLBNMKHF_00288 9.4e-302 asp2 3.4.11.5 S Accessory Sec system protein Asp2
NLBNMKHF_00289 1.6e-68 asp3 S Accessory Sec system protein Asp3
NLBNMKHF_00290 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NLBNMKHF_00291 3.9e-13 S Accessory secretory protein Sec Asp4
NLBNMKHF_00292 7e-12 S Accessory secretory protein Sec, Asp5
NLBNMKHF_00293 2.6e-73 L PFAM Integrase, catalytic core
NLBNMKHF_00294 2.6e-73 L PFAM Integrase, catalytic core
NLBNMKHF_00295 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NLBNMKHF_00296 0.0 comEC S Competence protein ComEC
NLBNMKHF_00297 1.1e-92 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
NLBNMKHF_00298 9.8e-143 plsC 2.3.1.51 I Acyltransferase
NLBNMKHF_00299 1.2e-156 nodB3 G deacetylase
NLBNMKHF_00300 5.5e-141 yabB 2.1.1.223 L Methyltransferase
NLBNMKHF_00301 7e-43 yazA L endonuclease containing a URI domain
NLBNMKHF_00302 2.2e-245 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NLBNMKHF_00303 1.6e-152 corA P CorA-like protein
NLBNMKHF_00304 2.1e-61 yjqA S Bacterial PH domain
NLBNMKHF_00305 5.8e-95 thiT S Thiamine transporter
NLBNMKHF_00306 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NLBNMKHF_00307 3.1e-116 ywaF S Integral membrane protein (intg_mem_TP0381)
NLBNMKHF_00308 9.2e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NLBNMKHF_00312 2.8e-154 cjaA ET ABC transporter substrate-binding protein
NLBNMKHF_00313 9.9e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
NLBNMKHF_00314 3e-106 P ABC transporter (Permease
NLBNMKHF_00315 2.5e-113 papP P ABC transporter (Permease
NLBNMKHF_00316 1.2e-191 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NLBNMKHF_00317 2.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
NLBNMKHF_00318 0.0 copA 3.6.3.54 P P-type ATPase
NLBNMKHF_00319 8.8e-72 copY K negative regulation of transcription, DNA-templated
NLBNMKHF_00320 7.2e-177 EGP Major facilitator Superfamily
NLBNMKHF_00321 2.3e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NLBNMKHF_00322 6.5e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NLBNMKHF_00323 1.4e-96 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
NLBNMKHF_00324 9.4e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
NLBNMKHF_00325 5.6e-178 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NLBNMKHF_00326 2.7e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
NLBNMKHF_00327 2.8e-257 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NLBNMKHF_00328 1.2e-40 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase type II
NLBNMKHF_00329 3.5e-120 yujD V lipoprotein transporter activity
NLBNMKHF_00330 0.0 S bacteriocin-associated integral membrane protein
NLBNMKHF_00331 2.1e-19 S Bacteriocin (Lactococcin_972)
NLBNMKHF_00332 4.3e-59
NLBNMKHF_00333 0.0 ctpE P E1-E2 ATPase
NLBNMKHF_00334 1.8e-47
NLBNMKHF_00337 1.9e-107 S Domain of Unknown Function with PDB structure (DUF3862)
NLBNMKHF_00340 2.5e-204 rpsA 1.17.7.4 J ribosomal protein S1
NLBNMKHF_00343 4.8e-16 S Protein of unknown function (DUF2969)
NLBNMKHF_00344 2.6e-199 ilvE 2.6.1.42 E Aminotransferase
NLBNMKHF_00345 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NLBNMKHF_00347 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NLBNMKHF_00348 1.8e-108 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NLBNMKHF_00349 4.8e-13 L Helix-hairpin-helix DNA-binding motif class 1
NLBNMKHF_00350 2.2e-30 S Domain of unknown function (DUF1912)
NLBNMKHF_00351 1.1e-178 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
NLBNMKHF_00352 1.8e-251 mmuP E amino acid
NLBNMKHF_00353 1.1e-109 engB D Necessary for normal cell division and for the maintenance of normal septation
NLBNMKHF_00354 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NLBNMKHF_00355 9.7e-22
NLBNMKHF_00356 9.6e-94 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NLBNMKHF_00357 5.9e-168 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NLBNMKHF_00358 7.9e-216 mvaS 2.3.3.10 I synthase
NLBNMKHF_00359 4.7e-230 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
NLBNMKHF_00360 3e-78 K hmm pf08876
NLBNMKHF_00361 5.2e-119 yqfA K protein, Hemolysin III
NLBNMKHF_00362 4.1e-29 pspC KT PspC domain protein
NLBNMKHF_00363 1.1e-200 S Protein of unknown function (DUF3114)
NLBNMKHF_00364 1.2e-158 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NLBNMKHF_00365 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NLBNMKHF_00366 2.6e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
NLBNMKHF_00367 2.6e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
NLBNMKHF_00368 0.0 U protein secretion
NLBNMKHF_00369 1.2e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NLBNMKHF_00370 2e-26
NLBNMKHF_00371 7.7e-97 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
NLBNMKHF_00372 2.6e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NLBNMKHF_00373 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
NLBNMKHF_00374 1.8e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NLBNMKHF_00375 4.6e-164 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
NLBNMKHF_00376 2.4e-170 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NLBNMKHF_00377 1.7e-133 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
NLBNMKHF_00378 1.7e-102 GBS0088 J protein conserved in bacteria
NLBNMKHF_00379 9.5e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NLBNMKHF_00380 5.5e-217 araT 2.6.1.1 E Aminotransferase
NLBNMKHF_00381 6.1e-140 recO L Involved in DNA repair and RecF pathway recombination
NLBNMKHF_00382 9.5e-181 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NLBNMKHF_00383 1.8e-29 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NLBNMKHF_00384 8.9e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NLBNMKHF_00385 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NLBNMKHF_00386 8.4e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NLBNMKHF_00387 1.4e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NLBNMKHF_00388 6.8e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NLBNMKHF_00389 2.8e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NLBNMKHF_00390 3e-237 purD 6.3.4.13 F Belongs to the GARS family
NLBNMKHF_00391 4.5e-80 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NLBNMKHF_00392 2.3e-201 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NLBNMKHF_00393 1.1e-175 1.1.1.169 H Ketopantoate reductase
NLBNMKHF_00394 6.6e-34
NLBNMKHF_00395 9.6e-135 J Domain of unknown function (DUF4041)
NLBNMKHF_00396 2.5e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NLBNMKHF_00397 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NLBNMKHF_00398 3.1e-69 argR K Regulates arginine biosynthesis genes
NLBNMKHF_00399 1.9e-56 ymcA 3.6.3.21 S Belongs to the UPF0342 family
NLBNMKHF_00400 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NLBNMKHF_00401 1.9e-77 S Protein of unknown function (DUF3021)
NLBNMKHF_00402 2.4e-69 K LytTr DNA-binding domain
NLBNMKHF_00404 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NLBNMKHF_00406 3e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NLBNMKHF_00407 2.3e-104 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
NLBNMKHF_00408 4e-229 cinA 3.5.1.42 S Belongs to the CinA family
NLBNMKHF_00409 1e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NLBNMKHF_00410 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
NLBNMKHF_00412 3.3e-117 nudL L hydrolase
NLBNMKHF_00413 9.1e-53 K transcriptional regulator, PadR family
NLBNMKHF_00414 1.9e-61 XK27_06920 S Protein of unknown function (DUF1700)
NLBNMKHF_00415 3.7e-106 S Putative adhesin
NLBNMKHF_00416 1.7e-156 XK27_06930 V domain protein
NLBNMKHF_00417 4.6e-94 XK27_06935 K transcriptional regulator
NLBNMKHF_00418 3.8e-52 ypaA M Membrane
NLBNMKHF_00419 1.1e-10
NLBNMKHF_00420 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NLBNMKHF_00421 1.8e-47 veg S Biofilm formation stimulator VEG
NLBNMKHF_00422 1e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NLBNMKHF_00423 2.2e-73 rplI J binds to the 23S rRNA
NLBNMKHF_00424 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NLBNMKHF_00425 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NLBNMKHF_00426 4.2e-99 yvbG U UPF0056 membrane protein
NLBNMKHF_00427 2.8e-218 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NLBNMKHF_00428 0.0 S Bacterial membrane protein, YfhO
NLBNMKHF_00429 3.2e-63 isaA GH23 M Immunodominant staphylococcal antigen A
NLBNMKHF_00430 3.3e-58 lytE M LysM domain protein
NLBNMKHF_00431 1.7e-132 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NLBNMKHF_00432 3.6e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NLBNMKHF_00433 3.1e-150 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NLBNMKHF_00434 4.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NLBNMKHF_00435 8.3e-130 S sequence-specific DNA binding
NLBNMKHF_00436 9.5e-239 ymfH S Peptidase M16
NLBNMKHF_00437 4.2e-231 ymfF S Peptidase M16
NLBNMKHF_00438 5.8e-59 yaaA S S4 domain protein YaaA
NLBNMKHF_00439 1.2e-202 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NLBNMKHF_00440 8.1e-274 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NLBNMKHF_00441 1.2e-191 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
NLBNMKHF_00442 7.1e-153 yvjA S membrane
NLBNMKHF_00443 1.1e-305 ybiT S abc transporter atp-binding protein
NLBNMKHF_00444 0.0 XK27_10405 S Bacterial membrane protein YfhO
NLBNMKHF_00445 6.4e-111 L Transposase
NLBNMKHF_00447 1.4e-142 L Transposase
NLBNMKHF_00448 1e-237 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NLBNMKHF_00450 9.4e-81 S ECF-type riboflavin transporter, S component
NLBNMKHF_00451 1e-143 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
NLBNMKHF_00452 6.1e-83 XK27_01265 S ECF-type riboflavin transporter, S component
NLBNMKHF_00453 1.1e-294 yfmM S abc transporter atp-binding protein
NLBNMKHF_00454 1.4e-256 noxE P NADH oxidase
NLBNMKHF_00455 4.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NLBNMKHF_00456 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NLBNMKHF_00457 9.3e-133 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
NLBNMKHF_00458 2.4e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
NLBNMKHF_00459 5.8e-164 ypuA S secreted protein
NLBNMKHF_00460 3.9e-229 mntH P Mn2 and Fe2 transporters of the NRAMP family
NLBNMKHF_00461 4.4e-45 rpmE2 J 50S ribosomal protein L31
NLBNMKHF_00462 4.6e-174 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NLBNMKHF_00463 1.7e-176 nrnA 3.1.13.3, 3.1.3.7 S domain protein
NLBNMKHF_00464 4.9e-153 gst O Glutathione S-transferase
NLBNMKHF_00465 5.8e-183 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NLBNMKHF_00466 5.1e-110 tdk 2.7.1.21 F thymidine kinase
NLBNMKHF_00467 3.6e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NLBNMKHF_00468 8.3e-143 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NLBNMKHF_00469 4.5e-106 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NLBNMKHF_00470 2.7e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NLBNMKHF_00471 2.1e-177 ndpA S 37-kD nucleoid-associated bacterial protein
NLBNMKHF_00472 1.4e-99 pvaA M lytic transglycosylase activity
NLBNMKHF_00473 2.2e-294 yfiB1 V abc transporter atp-binding protein
NLBNMKHF_00474 0.0 XK27_10035 V abc transporter atp-binding protein
NLBNMKHF_00475 1.3e-298 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NLBNMKHF_00476 1.7e-237 dltB M Membrane protein involved in D-alanine export
NLBNMKHF_00477 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NLBNMKHF_00478 2.2e-243 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NLBNMKHF_00479 0.0 3.6.3.8 P cation transport ATPase
NLBNMKHF_00480 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
NLBNMKHF_00482 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NLBNMKHF_00483 1.6e-165 metF 1.5.1.20 E reductase
NLBNMKHF_00484 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
NLBNMKHF_00485 4.1e-93 panT S ECF transporter, substrate-specific component
NLBNMKHF_00486 2.2e-91 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NLBNMKHF_00487 1.9e-116 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
NLBNMKHF_00488 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NLBNMKHF_00489 9.4e-121 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NLBNMKHF_00490 1.3e-241 T PhoQ Sensor
NLBNMKHF_00491 1e-29 rpsT J Binds directly to 16S ribosomal RNA
NLBNMKHF_00492 2.8e-171 coaA 2.7.1.33 F Pantothenic acid kinase
NLBNMKHF_00493 1.1e-104 rsmC 2.1.1.172 J Methyltransferase small domain protein
NLBNMKHF_00494 1.9e-231 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
NLBNMKHF_00495 3.5e-112 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NLBNMKHF_00496 1.3e-64 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NLBNMKHF_00497 2.8e-191 tcsA S membrane
NLBNMKHF_00498 6.4e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
NLBNMKHF_00499 5.1e-177 yufP S Belongs to the binding-protein-dependent transport system permease family
NLBNMKHF_00500 5e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
NLBNMKHF_00501 6.8e-113 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
NLBNMKHF_00502 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NLBNMKHF_00503 8.6e-76 ypmB S Protein conserved in bacteria
NLBNMKHF_00504 2.8e-213 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NLBNMKHF_00505 9.3e-261 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NLBNMKHF_00506 1.8e-18
NLBNMKHF_00507 8.1e-200 pmrB EGP Major facilitator Superfamily
NLBNMKHF_00508 2.3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
NLBNMKHF_00509 2.6e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NLBNMKHF_00510 8.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
NLBNMKHF_00511 4.6e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NLBNMKHF_00512 1.4e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
NLBNMKHF_00513 6.6e-202 D nuclear chromosome segregation
NLBNMKHF_00514 1.4e-136 yejC S cyclic nucleotide-binding protein
NLBNMKHF_00515 1.6e-163 rapZ S Displays ATPase and GTPase activities
NLBNMKHF_00516 1.4e-181 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NLBNMKHF_00517 2.2e-160 whiA K May be required for sporulation
NLBNMKHF_00518 4e-275 pepD E Dipeptidase
NLBNMKHF_00519 4.6e-146 XK27_10720 D peptidase activity
NLBNMKHF_00520 5.6e-294 adcA P Belongs to the bacterial solute-binding protein 9 family
NLBNMKHF_00521 2.6e-09
NLBNMKHF_00523 7.4e-170 yeiH S Membrane
NLBNMKHF_00524 1.3e-128 mur1 3.4.17.14, 3.5.1.28 NU muramidase
NLBNMKHF_00525 2.9e-165 cpsY K Transcriptional regulator
NLBNMKHF_00526 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NLBNMKHF_00527 6.6e-59 phnA P Alkylphosphonate utilization operon protein PhnA
NLBNMKHF_00528 1.4e-105 artQ P ABC transporter (Permease
NLBNMKHF_00529 8.8e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
NLBNMKHF_00530 7.9e-157 aatB ET ABC transporter substrate-binding protein
NLBNMKHF_00531 1.5e-269 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NLBNMKHF_00532 1.4e-49
NLBNMKHF_00533 1.8e-44
NLBNMKHF_00534 3e-187 adhP 1.1.1.1 C alcohol dehydrogenase
NLBNMKHF_00535 2.2e-102 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NLBNMKHF_00536 2.3e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NLBNMKHF_00537 1e-125 gntR1 K transcriptional
NLBNMKHF_00538 2e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NLBNMKHF_00539 1.9e-273 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NLBNMKHF_00540 2.7e-86
NLBNMKHF_00541 2.7e-91 niaR S small molecule binding protein (contains 3H domain)
NLBNMKHF_00542 4e-127 K DNA-binding helix-turn-helix protein
NLBNMKHF_00543 2.1e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NLBNMKHF_00544 7.7e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NLBNMKHF_00545 4.4e-161 GK ROK family
NLBNMKHF_00546 2.5e-155 dprA LU DNA protecting protein DprA
NLBNMKHF_00547 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NLBNMKHF_00548 4.6e-83 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
NLBNMKHF_00549 1.3e-51 V ABC-2 family transporter protein
NLBNMKHF_00551 2e-149 S TraX protein
NLBNMKHF_00552 1.5e-118 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NLBNMKHF_00553 4.7e-236 T PhoQ Sensor
NLBNMKHF_00554 1.1e-258 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NLBNMKHF_00555 5.9e-85 XK27_05470 E Methionine synthase
NLBNMKHF_00556 2e-111 XK27_05470 E Methionine synthase
NLBNMKHF_00557 8.6e-57 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NLBNMKHF_00558 8e-252 V Glucan-binding protein C
NLBNMKHF_00559 1.5e-121 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NLBNMKHF_00560 1.3e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NLBNMKHF_00561 5.5e-95 S Protein of unknown function (DUF1697)
NLBNMKHF_00562 2.9e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NLBNMKHF_00563 4.7e-182 clcA_2 P Chloride transporter, ClC family
NLBNMKHF_00564 5.8e-137 yfeJ 6.3.5.2 F glutamine amidotransferase
NLBNMKHF_00565 4e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
NLBNMKHF_00566 1e-20 L the current gene model (or a revised gene model) may contain a frame shift
NLBNMKHF_00568 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NLBNMKHF_00571 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NLBNMKHF_00572 3.1e-130 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
NLBNMKHF_00573 2.8e-41 C Pyridoxamine 5'-phosphate oxidase
NLBNMKHF_00574 2.6e-96 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
NLBNMKHF_00575 9.4e-12 S Macro domain
NLBNMKHF_00576 4e-36 S Macro domain
NLBNMKHF_00577 2.3e-67 mgrA K Transcriptional regulator, MarR family
NLBNMKHF_00578 4.6e-133 1.6.5.2 GM NmrA-like family
NLBNMKHF_00579 4.5e-169 C alcohol dehydrogenase
NLBNMKHF_00580 4.6e-129 proV E abc transporter atp-binding protein
NLBNMKHF_00581 1e-263 proWX P ABC transporter
NLBNMKHF_00582 6.5e-108 magIII L Base excision DNA repair protein, HhH-GPD family
NLBNMKHF_00583 4.4e-141 S Phenazine biosynthesis protein
NLBNMKHF_00584 2.2e-92 2.7.7.65 T Psort location CytoplasmicMembrane, score
NLBNMKHF_00585 1.3e-132 cbiQ P Cobalt transport protein
NLBNMKHF_00586 5.9e-157 P abc transporter atp-binding protein
NLBNMKHF_00587 9.7e-149 cbiO2 P 'abc transporter, ATP-binding protein
NLBNMKHF_00588 3e-113 tnp L DDE domain
NLBNMKHF_00589 2e-74 pnuC H nicotinamide mononucleotide transporter
NLBNMKHF_00590 1.8e-11
NLBNMKHF_00591 5.9e-61 S Protein of unknown function with HXXEE motif
NLBNMKHF_00592 1.4e-104 K Transcriptional regulator, TetR family
NLBNMKHF_00593 7.3e-161 czcD P cation diffusion facilitator family transporter
NLBNMKHF_00594 6.1e-194 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NLBNMKHF_00595 3.4e-186 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
NLBNMKHF_00596 2e-236 S the current gene model (or a revised gene model) may contain a frame shift
NLBNMKHF_00597 5.4e-110 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
NLBNMKHF_00598 9.6e-21 V Type III restriction enzyme, res subunit
NLBNMKHF_00599 1.2e-106 V Type III restriction enzyme, res subunit
NLBNMKHF_00600 1.5e-21 V Type III restriction enzyme, res subunit
NLBNMKHF_00601 1.9e-170 P abc-type fe3 -hydroxamate transport system, periplasmic component
NLBNMKHF_00602 1.4e-232 dinF V Mate efflux family protein
NLBNMKHF_00603 2.4e-260 S Psort location CytoplasmicMembrane, score
NLBNMKHF_00604 3.3e-308 FbpA K RNA-binding protein homologous to eukaryotic snRNP
NLBNMKHF_00605 1.3e-132 S TraX protein
NLBNMKHF_00606 2.6e-92 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
NLBNMKHF_00607 5e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NLBNMKHF_00608 6.5e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NLBNMKHF_00609 4.5e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NLBNMKHF_00610 4.4e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NLBNMKHF_00611 1.1e-240 nylA 3.5.1.4 J Belongs to the amidase family
NLBNMKHF_00612 1.3e-148 yckB ET Belongs to the bacterial solute-binding protein 3 family
NLBNMKHF_00613 6.4e-82 yecS P ABC transporter (Permease
NLBNMKHF_00614 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
NLBNMKHF_00615 2.7e-177 bglC K Transcriptional regulator
NLBNMKHF_00616 5.6e-245 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NLBNMKHF_00617 4.3e-242 agcS E (Alanine) symporter
NLBNMKHF_00618 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NLBNMKHF_00619 4.3e-239 metY 2.5.1.49 E o-acetylhomoserine
NLBNMKHF_00620 2.9e-27 S haloacid dehalogenase-like hydrolase
NLBNMKHF_00621 8.7e-60 S haloacid dehalogenase-like hydrolase
NLBNMKHF_00622 4.2e-86 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NLBNMKHF_00623 1.3e-111 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
NLBNMKHF_00624 4.7e-35 M1-755 S Domain of unknown function (DUF1858)
NLBNMKHF_00625 6.9e-248 XK27_04775 S hemerythrin HHE cation binding domain
NLBNMKHF_00626 3.2e-150 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NLBNMKHF_00627 1.3e-170 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NLBNMKHF_00628 1.6e-70 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NLBNMKHF_00629 1e-44 yktA S Belongs to the UPF0223 family
NLBNMKHF_00630 2e-143 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
NLBNMKHF_00631 6.9e-253 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
NLBNMKHF_00632 9e-156 pstS P phosphate
NLBNMKHF_00633 1.9e-156 pstC P probably responsible for the translocation of the substrate across the membrane
NLBNMKHF_00634 1.5e-155 pstA P phosphate transport system permease
NLBNMKHF_00635 4e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NLBNMKHF_00636 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NLBNMKHF_00637 3.2e-113 phoU P Plays a role in the regulation of phosphate uptake
NLBNMKHF_00638 0.0 pepN 3.4.11.2 E aminopeptidase
NLBNMKHF_00639 6e-194 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
NLBNMKHF_00640 1.9e-186 lplA 6.3.1.20 H Lipoate-protein ligase
NLBNMKHF_00642 1.7e-11
NLBNMKHF_00643 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NLBNMKHF_00644 1.2e-301 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
NLBNMKHF_00645 8.7e-171 malR K Transcriptional regulator
NLBNMKHF_00646 9.6e-228 malX G ABC transporter
NLBNMKHF_00647 9.7e-250 malF P ABC transporter (Permease
NLBNMKHF_00648 9.8e-152 malG P ABC transporter (Permease
NLBNMKHF_00649 1.8e-212 msmX P Belongs to the ABC transporter superfamily
NLBNMKHF_00650 6.1e-25 tatA U protein secretion
NLBNMKHF_00651 1.3e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NLBNMKHF_00652 5.7e-292 ywbL P COG0672 High-affinity Fe2 Pb2 permease
NLBNMKHF_00653 7.6e-230 ycdB P peroxidase
NLBNMKHF_00654 4.9e-146 ycdO P periplasmic lipoprotein involved in iron transport
NLBNMKHF_00655 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NLBNMKHF_00656 2.9e-267 3.5.1.28 M N-Acetylmuramoyl-L-alanine amidase
NLBNMKHF_00657 4.4e-62 rplQ J ribosomal protein l17
NLBNMKHF_00658 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NLBNMKHF_00659 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NLBNMKHF_00660 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NLBNMKHF_00661 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NLBNMKHF_00662 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NLBNMKHF_00663 6.2e-114 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NLBNMKHF_00664 3e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NLBNMKHF_00665 5.7e-58 rplO J binds to the 23S rRNA
NLBNMKHF_00666 1.9e-23 rpmD J ribosomal protein l30
NLBNMKHF_00667 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NLBNMKHF_00668 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NLBNMKHF_00669 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NLBNMKHF_00670 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NLBNMKHF_00671 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NLBNMKHF_00672 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NLBNMKHF_00673 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NLBNMKHF_00674 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NLBNMKHF_00675 1.7e-38 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NLBNMKHF_00676 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
NLBNMKHF_00677 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NLBNMKHF_00678 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NLBNMKHF_00679 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NLBNMKHF_00680 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NLBNMKHF_00681 6.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NLBNMKHF_00682 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NLBNMKHF_00683 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
NLBNMKHF_00684 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NLBNMKHF_00685 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
NLBNMKHF_00686 3e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NLBNMKHF_00687 0.0 XK27_09800 I Acyltransferase
NLBNMKHF_00688 4.8e-35 XK27_09805 S MORN repeat protein
NLBNMKHF_00689 3.4e-79 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NLBNMKHF_00690 2.7e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NLBNMKHF_00691 4.8e-93 adk 2.7.4.3 F topology modulation protein
NLBNMKHF_00692 4.9e-174 yeiH S membrane
NLBNMKHF_00693 5.5e-89 K sequence-specific DNA binding
NLBNMKHF_00694 2.6e-140 L Replication initiation factor
NLBNMKHF_00695 1.9e-18 S Domain of unknown function (DUF3173)
NLBNMKHF_00696 1.3e-215 int L Belongs to the 'phage' integrase family
NLBNMKHF_00698 7e-234 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
NLBNMKHF_00699 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NLBNMKHF_00700 6.3e-44 yrzL S Belongs to the UPF0297 family
NLBNMKHF_00701 2.3e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NLBNMKHF_00702 3.2e-44 yrzB S Belongs to the UPF0473 family
NLBNMKHF_00703 0.0 M Putative cell wall binding repeat
NLBNMKHF_00704 1.6e-237 tcdB S dextransucrase activity
NLBNMKHF_00705 0.0 S dextransucrase activity
NLBNMKHF_00706 2.1e-103 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NLBNMKHF_00707 1.8e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NLBNMKHF_00708 0.0 M Putative cell wall binding repeat
NLBNMKHF_00709 1.1e-302 S dextransucrase activity
NLBNMKHF_00710 0.0 S dextransucrase activity
NLBNMKHF_00711 0.0 S dextransucrase activity
NLBNMKHF_00713 3.6e-99 XK27_00785 S CAAX protease self-immunity
NLBNMKHF_00714 3.5e-239 EGP Major facilitator Superfamily
NLBNMKHF_00715 1.8e-66 rmaI K Transcriptional regulator, MarR family
NLBNMKHF_00716 6.7e-88 maa 2.3.1.79 GK Maltose O-acetyltransferase
NLBNMKHF_00717 6.1e-137 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
NLBNMKHF_00718 0.0 3.5.1.28 M domain protein
NLBNMKHF_00719 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
NLBNMKHF_00720 1.5e-109 K Helix-turn-helix domain, rpiR family
NLBNMKHF_00721 9.6e-17 3.2.1.51 GH95 U LPXTG cell wall anchor motif
NLBNMKHF_00722 1.3e-153 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
NLBNMKHF_00723 2.5e-109 pgm G Belongs to the phosphoglycerate mutase family
NLBNMKHF_00724 7e-107 G Belongs to the phosphoglycerate mutase family
NLBNMKHF_00725 1.5e-109 G Belongs to the phosphoglycerate mutase family
NLBNMKHF_00726 2.9e-199 S hmm pf01594
NLBNMKHF_00727 1.2e-287 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NLBNMKHF_00728 4.9e-39 S granule-associated protein
NLBNMKHF_00729 4.8e-285 S unusual protein kinase
NLBNMKHF_00730 3.7e-103 estA E Lysophospholipase L1 and related esterases
NLBNMKHF_00731 2.7e-157 rssA S Phospholipase, patatin family
NLBNMKHF_00732 4.4e-181 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
NLBNMKHF_00733 2.3e-246 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
NLBNMKHF_00734 4.3e-217 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NLBNMKHF_00735 1.7e-119 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NLBNMKHF_00736 4.8e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NLBNMKHF_00737 0.0 S the current gene model (or a revised gene model) may contain a frame shift
NLBNMKHF_00738 2.4e-234 2.7.13.3 T protein histidine kinase activity
NLBNMKHF_00739 1.1e-215 hpk9 2.7.13.3 T protein histidine kinase activity
NLBNMKHF_00740 6.6e-184 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
NLBNMKHF_00741 1.4e-181 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NLBNMKHF_00742 8.1e-212 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NLBNMKHF_00743 0.0 lpdA 1.8.1.4 C Dehydrogenase
NLBNMKHF_00744 3.6e-222 sip L Belongs to the 'phage' integrase family
NLBNMKHF_00745 1.2e-28 S MerR HTH family regulatory protein
NLBNMKHF_00746 4.6e-201
NLBNMKHF_00747 1.5e-95 D ftsk spoiiie
NLBNMKHF_00753 4.1e-48 K DNA-binding protein
NLBNMKHF_00754 2.5e-80
NLBNMKHF_00755 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NLBNMKHF_00756 1.5e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NLBNMKHF_00757 3.3e-219 metE 2.1.1.14 E Methionine synthase
NLBNMKHF_00758 1.1e-240 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
NLBNMKHF_00759 2.5e-239 hisS 6.1.1.21 J histidyl-tRNA synthetase
NLBNMKHF_00761 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NLBNMKHF_00762 2.7e-166 XK27_01785 S cog cog1284
NLBNMKHF_00763 8.3e-120 yaaA S Belongs to the UPF0246 family
NLBNMKHF_00764 6.7e-179 L Transposase
NLBNMKHF_00765 3e-173 L Transposase
NLBNMKHF_00766 6.6e-173 L Transposase
NLBNMKHF_00770 6.2e-120 yoaK S Protein of unknown function (DUF1275)
NLBNMKHF_00771 4.8e-85 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NLBNMKHF_00772 9.2e-207 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
NLBNMKHF_00773 1.9e-133 parB K Belongs to the ParB family
NLBNMKHF_00774 1e-254 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NLBNMKHF_00775 7.2e-198 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NLBNMKHF_00776 1.1e-29 yyzM S Protein conserved in bacteria
NLBNMKHF_00777 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NLBNMKHF_00778 2e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NLBNMKHF_00779 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NLBNMKHF_00780 6.3e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NLBNMKHF_00781 3e-60 divIC D Septum formation initiator
NLBNMKHF_00783 4.5e-236 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
NLBNMKHF_00784 1.1e-236 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NLBNMKHF_00785 2e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NLBNMKHF_00786 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NLBNMKHF_00789 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NLBNMKHF_00790 0.0 pepO 3.4.24.71 O Peptidase family M13
NLBNMKHF_00791 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NLBNMKHF_00792 2.1e-288 treB 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
NLBNMKHF_00793 1.7e-53 treB 2.7.1.201 G pts system
NLBNMKHF_00794 2.3e-125 treR K trehalose operon
NLBNMKHF_00795 4.3e-95 ywlG S Belongs to the UPF0340 family
NLBNMKHF_00798 8.2e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
NLBNMKHF_00800 8.1e-238 6.3.2.2 H gamma-glutamylcysteine synthetase
NLBNMKHF_00801 1.2e-53 L Transposase
NLBNMKHF_00802 1.3e-276 thrC 4.2.3.1 E Threonine synthase
NLBNMKHF_00803 7.1e-226 norN V Mate efflux family protein
NLBNMKHF_00804 1.4e-57 asp S cog cog1302
NLBNMKHF_00805 3.8e-304 yloV S kinase related to dihydroxyacetone kinase
NLBNMKHF_00806 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NLBNMKHF_00807 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
NLBNMKHF_00808 2.2e-76 ilvN 2.2.1.6 E Acetolactate synthase
NLBNMKHF_00809 3e-195 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NLBNMKHF_00810 6.6e-215 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NLBNMKHF_00811 8.4e-137
NLBNMKHF_00813 5.5e-250 ydaM M Glycosyltransferases, probably involved in cell wall biogenesis
NLBNMKHF_00814 2e-208 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
NLBNMKHF_00816 2e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NLBNMKHF_00817 5.5e-26 epuA S DNA-directed RNA polymerase subunit beta
NLBNMKHF_00818 6.5e-154 endA F DNA RNA non-specific endonuclease
NLBNMKHF_00819 3.4e-14 rpmH J Ribosomal protein L34
NLBNMKHF_00820 6.9e-101 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
NLBNMKHF_00821 2.9e-105 K Transcriptional regulator
NLBNMKHF_00822 1.2e-151 jag S RNA-binding protein
NLBNMKHF_00823 9.7e-147 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NLBNMKHF_00824 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NLBNMKHF_00825 1.6e-263 argH 4.3.2.1 E Argininosuccinate lyase
NLBNMKHF_00826 5.8e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NLBNMKHF_00835 2.6e-10
NLBNMKHF_00838 1.9e-07
NLBNMKHF_00843 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NLBNMKHF_00844 1.6e-235 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
NLBNMKHF_00845 1.2e-35 XK27_02060 S Transglycosylase associated protein
NLBNMKHF_00846 2e-71 badR K Transcriptional regulator, marr family
NLBNMKHF_00847 1.1e-95 S reductase
NLBNMKHF_00848 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
NLBNMKHF_00849 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
NLBNMKHF_00850 1.1e-87 XK27_08075 M glycosyl transferase family 2
NLBNMKHF_00851 1.2e-72 XK27_08075 M glycosyl transferase family 2
NLBNMKHF_00852 4.9e-102 S Carbohydrate-binding domain-containing protein Cthe_2159
NLBNMKHF_00853 2.9e-142 P molecular chaperone
NLBNMKHF_00854 2.2e-93 XK27_05505 S Psort location CytoplasmicMembrane, score
NLBNMKHF_00857 4.1e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
NLBNMKHF_00858 3.6e-60 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NLBNMKHF_00859 3.6e-137 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NLBNMKHF_00860 2.4e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NLBNMKHF_00861 2.3e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NLBNMKHF_00862 1.1e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
NLBNMKHF_00863 1.4e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NLBNMKHF_00864 5.5e-118 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NLBNMKHF_00865 5.5e-178 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NLBNMKHF_00866 4.2e-192 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NLBNMKHF_00867 5.6e-40 XK27_08085
NLBNMKHF_00868 4.7e-147 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
NLBNMKHF_00869 6.7e-136 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
NLBNMKHF_00870 3.9e-116 ylfI S tigr01906
NLBNMKHF_00871 1e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NLBNMKHF_00872 1.4e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
NLBNMKHF_00873 8.2e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
NLBNMKHF_00874 3.7e-30 KT response to antibiotic
NLBNMKHF_00876 1.3e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NLBNMKHF_00877 2.7e-111 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NLBNMKHF_00878 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NLBNMKHF_00879 7.4e-258 S phospholipase Carboxylesterase
NLBNMKHF_00880 1.1e-200 yurR 1.4.5.1 E oxidoreductase
NLBNMKHF_00881 8e-146 zupT P Mediates zinc uptake. May also transport other divalent cations
NLBNMKHF_00882 2.2e-145 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NLBNMKHF_00883 2.6e-118 trmK 2.1.1.217 S SAM-dependent methyltransferase
NLBNMKHF_00884 5e-64 gtrA S GtrA-like protein
NLBNMKHF_00885 1.3e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NLBNMKHF_00886 6e-169 ybbR S Protein conserved in bacteria
NLBNMKHF_00887 1.5e-147 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NLBNMKHF_00888 4.5e-252 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
NLBNMKHF_00889 2.3e-150 cobQ S glutamine amidotransferase
NLBNMKHF_00890 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NLBNMKHF_00891 2e-132 pip 1.11.1.10 S Alpha beta hydrolase
NLBNMKHF_00892 5.3e-34 MA20_06245 S yiaA/B two helix domain
NLBNMKHF_00893 0.0 uup S abc transporter atp-binding protein
NLBNMKHF_00894 6.2e-114 udk 2.7.1.48 F Cytidine monophosphokinase
NLBNMKHF_00895 3.2e-179 yfmL 3.6.4.13 L DEAD DEAH box helicase
NLBNMKHF_00896 9.9e-227 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
NLBNMKHF_00897 2.7e-153 XK27_05675 S Esterase
NLBNMKHF_00898 6.1e-162 XK27_05670 S Putative esterase
NLBNMKHF_00899 1.1e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
NLBNMKHF_00900 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NLBNMKHF_00901 3e-38 ptsH G phosphocarrier protein Hpr
NLBNMKHF_00902 9.7e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
NLBNMKHF_00903 2.5e-211 citZ 2.3.3.1 C Belongs to the citrate synthase family
NLBNMKHF_00904 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NLBNMKHF_00905 2.9e-34 nrdH O Glutaredoxin
NLBNMKHF_00906 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NLBNMKHF_00907 8.5e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NLBNMKHF_00908 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NLBNMKHF_00909 8.4e-138 divIVA D Cell division initiation protein
NLBNMKHF_00910 2.7e-143 ylmH S conserved protein, contains S4-like domain
NLBNMKHF_00911 6.5e-30 yggT D integral membrane protein
NLBNMKHF_00912 3.2e-101 sepF D cell septum assembly
NLBNMKHF_00913 2.1e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NLBNMKHF_00914 1.7e-238 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NLBNMKHF_00915 7.1e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NLBNMKHF_00916 2.2e-133 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NLBNMKHF_00917 1.9e-200 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NLBNMKHF_00918 1e-251 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NLBNMKHF_00920 0.0 typA T GTP-binding protein TypA
NLBNMKHF_00921 3.5e-177 glk 2.7.1.2 G Glucokinase
NLBNMKHF_00922 2.4e-27 yqgQ S protein conserved in bacteria
NLBNMKHF_00923 5.2e-83 perR P Belongs to the Fur family
NLBNMKHF_00924 9.3e-92 dps P Belongs to the Dps family
NLBNMKHF_00925 7.5e-115 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
NLBNMKHF_00926 3.6e-172 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
NLBNMKHF_00927 9.4e-112 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
NLBNMKHF_00928 1.4e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
NLBNMKHF_00929 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NLBNMKHF_00930 4.8e-64 S Domain of unknown function (DUF4430)
NLBNMKHF_00931 6.7e-73 S Psort location CytoplasmicMembrane, score
NLBNMKHF_00932 6e-129 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
NLBNMKHF_00933 2.1e-133 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
NLBNMKHF_00934 3.9e-165 sitA P Belongs to the bacterial solute-binding protein 9 family
NLBNMKHF_00935 1.1e-118 sirR K iron dependent repressor
NLBNMKHF_00936 1.5e-134 htpX O Belongs to the peptidase M48B family
NLBNMKHF_00937 1.2e-92 lemA S LemA family
NLBNMKHF_00938 2.4e-176 spd F DNA RNA non-specific endonuclease
NLBNMKHF_00939 0.0 2.4.1.21 GT5 M Right handed beta helix region
NLBNMKHF_00941 1.9e-135 S double-stranded DNA endodeoxyribonuclease activity
NLBNMKHF_00942 1.8e-303 hsdM 2.1.1.72 V type I restriction-modification system
NLBNMKHF_00943 2.3e-123 S Protein conserved in bacteria
NLBNMKHF_00944 2.9e-188 S KAP family P-loop domain
NLBNMKHF_00945 1.3e-88 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
NLBNMKHF_00946 1.7e-12
NLBNMKHF_00947 2.4e-133 L Reverse transcriptase (RNA-dependent DNA polymerase)
NLBNMKHF_00948 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
NLBNMKHF_00950 2e-130 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NLBNMKHF_00951 2.7e-216 MA20_36090 S Protein of unknown function (DUF2974)
NLBNMKHF_00952 5.2e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NLBNMKHF_00953 5.7e-55 5.2.1.8 G hydrolase
NLBNMKHF_00954 1.6e-69 5.2.1.8 G hydrolase
NLBNMKHF_00955 5.3e-27 P Hemerythrin HHE cation binding domain protein
NLBNMKHF_00956 4.8e-144 XK27_00880 3.4.17.14, 3.5.1.28 M Glycosyl hydrolase, family 25
NLBNMKHF_00957 1e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NLBNMKHF_00958 4.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
NLBNMKHF_00959 1.5e-174 S hydrolase
NLBNMKHF_00960 8.4e-23
NLBNMKHF_00961 4.6e-137 M LysM domain
NLBNMKHF_00962 8.3e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NLBNMKHF_00964 8.7e-235 mntH P H( )-stimulated, divalent metal cation uptake system
NLBNMKHF_00965 1.8e-33 XK27_12190 S protein conserved in bacteria
NLBNMKHF_00967 1e-88 bioY S biotin synthase
NLBNMKHF_00968 4.4e-252 yegQ O Peptidase U32
NLBNMKHF_00969 6.8e-178 yegQ O Peptidase U32
NLBNMKHF_00971 3e-67 ytxH S General stress protein
NLBNMKHF_00972 3.7e-08 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NLBNMKHF_00973 1.2e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NLBNMKHF_00974 2.2e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NLBNMKHF_00975 2.9e-41 pspC KT PspC domain
NLBNMKHF_00976 0.0 yhgF K Transcriptional accessory protein
NLBNMKHF_00978 1.9e-156 XK27_03015 S permease
NLBNMKHF_00979 2.4e-147 ycgQ S TIGR03943 family
NLBNMKHF_00980 5.5e-168 S CRISPR-associated protein Csn2 subfamily St
NLBNMKHF_00981 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NLBNMKHF_00982 3.5e-171 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NLBNMKHF_00983 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NLBNMKHF_00984 1.1e-284 sulP P Sulfate permease and related transporters (MFS superfamily)
NLBNMKHF_00985 3.6e-103
NLBNMKHF_00986 2.9e-119 estA E GDSL-like Lipase/Acylhydrolase
NLBNMKHF_00987 2.3e-94 S CAAX protease self-immunity
NLBNMKHF_00988 3e-49
NLBNMKHF_00990 2.8e-63 yqeB S Pyrimidine dimer DNA glycosylase
NLBNMKHF_00991 4.1e-60 S Protein of unknown function (DUF1722)
NLBNMKHF_00992 1.3e-19 M Bacterial lipoprotein
NLBNMKHF_00993 1.2e-10
NLBNMKHF_00994 2.8e-126 V CAAX protease self-immunity
NLBNMKHF_00995 7.1e-47
NLBNMKHF_00996 3.4e-74 K TetR family transcriptional regulator
NLBNMKHF_00997 4.2e-80 Q Methyltransferase domain
NLBNMKHF_00998 1e-141 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NLBNMKHF_00999 1.3e-174 acoB C dehydrogenase E1 component
NLBNMKHF_01000 3.6e-167 acoA C Acetoin dehydrogenase E1 component subunit alpha
NLBNMKHF_01001 9.5e-173 pdhD 1.8.1.4 C Dehydrogenase
NLBNMKHF_01002 3.3e-08 K CsbD-like
NLBNMKHF_01003 7.7e-68 S Asp23 family, cell envelope-related function
NLBNMKHF_01004 1.5e-22 S Small integral membrane protein
NLBNMKHF_01005 4.7e-97
NLBNMKHF_01006 2.3e-29 S Membrane
NLBNMKHF_01008 4.7e-172 S Domain of unknown function (DUF389)
NLBNMKHF_01009 1.3e-157 yegS 2.7.1.107 I Diacylglycerol kinase
NLBNMKHF_01010 3.4e-126 ybbA S Putative esterase
NLBNMKHF_01011 2.9e-174 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
NLBNMKHF_01012 9.8e-135 fecE 3.6.3.34 HP ABC transporter
NLBNMKHF_01013 3.9e-158 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLBNMKHF_01014 4.6e-116 V CAAX protease self-immunity
NLBNMKHF_01015 1.2e-152 S Domain of unknown function (DUF4300)
NLBNMKHF_01016 6.3e-91 tetR K transcriptional regulator
NLBNMKHF_01017 1.5e-282 norB P Major facilitator superfamily
NLBNMKHF_01018 2.4e-115 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NLBNMKHF_01019 4.6e-88 XK27_10930 K acetyltransferase
NLBNMKHF_01020 7.5e-14
NLBNMKHF_01021 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NLBNMKHF_01022 5.8e-289 ccs S the current gene model (or a revised gene model) may contain a frame shift
NLBNMKHF_01024 0.0 S dextransucrase activity
NLBNMKHF_01025 0.0 S dextransucrase activity
NLBNMKHF_01026 1.1e-89 usp 3.5.1.28 CBM50 S CHAP domain
NLBNMKHF_01027 4.2e-84 mreD M rod shape-determining protein MreD
NLBNMKHF_01028 9.2e-110 mreC M Involved in formation and maintenance of cell shape
NLBNMKHF_01035 0.0 S dextransucrase activity
NLBNMKHF_01037 3.2e-10 3.4.24.40 U Large extracellular alpha-helical protein
NLBNMKHF_01038 6.7e-139 glnQ 3.6.3.21 E abc transporter atp-binding protein
NLBNMKHF_01039 1.6e-41 M Pilin isopeptide linkage domain protein
NLBNMKHF_01041 0.0 glgE 2.3.1.12, 2.4.99.16, 3.2.1.1, 3.2.1.14 GH13,GH18 M Pilin isopeptide linkage domain protein
NLBNMKHF_01042 3.7e-189 XK27_10075 S abc transporter atp-binding protein
NLBNMKHF_01043 0.0 V abc transporter atp-binding protein
NLBNMKHF_01044 3.6e-297 V abc transporter atp-binding protein
NLBNMKHF_01045 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
NLBNMKHF_01047 5.7e-291 S Protein of unknown function (DUF3114)
NLBNMKHF_01048 6.5e-99 2.3.1.128 K Acetyltransferase GNAT Family
NLBNMKHF_01049 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NLBNMKHF_01050 2.2e-284 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
NLBNMKHF_01051 5.2e-180 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
NLBNMKHF_01052 2e-187 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NLBNMKHF_01053 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NLBNMKHF_01054 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NLBNMKHF_01055 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NLBNMKHF_01056 1.2e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
NLBNMKHF_01057 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NLBNMKHF_01058 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NLBNMKHF_01061 1.4e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NLBNMKHF_01062 1.9e-170 vraS 2.7.13.3 T Histidine kinase
NLBNMKHF_01063 8.6e-117 yvqF S Membrane
NLBNMKHF_01064 3.8e-94 kcsA P Ion transport protein
NLBNMKHF_01065 1.4e-302 prkC 2.7.11.1 KLT serine threonine protein kinase
NLBNMKHF_01066 4.8e-137 stp 3.1.3.16 T phosphatase
NLBNMKHF_01067 3.2e-245 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NLBNMKHF_01068 2.8e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NLBNMKHF_01069 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NLBNMKHF_01070 3.6e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
NLBNMKHF_01071 8.8e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NLBNMKHF_01072 1.8e-195 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NLBNMKHF_01073 1.8e-142 XK27_02985 S overlaps another CDS with the same product name
NLBNMKHF_01074 6.1e-143 supH S overlaps another CDS with the same product name
NLBNMKHF_01075 6.1e-61 yvoA_1 K Transcriptional
NLBNMKHF_01076 2.3e-117 skfE V abc transporter atp-binding protein
NLBNMKHF_01077 1.7e-129 V Psort location CytoplasmicMembrane, score
NLBNMKHF_01078 3.1e-170 oppF P Belongs to the ABC transporter superfamily
NLBNMKHF_01079 1.3e-201 oppD P Belongs to the ABC transporter superfamily
NLBNMKHF_01080 3.5e-166 amiD P ABC transporter (Permease
NLBNMKHF_01081 4.3e-275 amiC P ABC transporter (Permease
NLBNMKHF_01082 2.7e-311 amiA E ABC transporter, substrate-binding protein, family 5
NLBNMKHF_01083 0.0 amiA E ABC transporter, substrate-binding protein, family 5
NLBNMKHF_01084 6.3e-174 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NLBNMKHF_01085 3.1e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
NLBNMKHF_01086 7.5e-152 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NLBNMKHF_01087 3e-119 yjbM 2.7.6.5 S Gtp pyrophosphokinase
NLBNMKHF_01088 7.1e-101 yjbK S Adenylate cyclase
NLBNMKHF_01089 5.1e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NLBNMKHF_01090 1.1e-203 iscS 2.8.1.7 E Cysteine desulfurase
NLBNMKHF_01091 1.8e-59 XK27_04120 S Putative amino acid metabolism
NLBNMKHF_01092 1.9e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NLBNMKHF_01093 5.3e-127 puuD T peptidase C26
NLBNMKHF_01094 1.2e-118 radC E Belongs to the UPF0758 family
NLBNMKHF_01095 7.5e-166
NLBNMKHF_01096 4.3e-46 M Psort location CytoplasmicMembrane, score
NLBNMKHF_01097 4.3e-156 rfbJ M Glycosyl transferase family 2
NLBNMKHF_01098 0.0 rgpF M Rhamnan synthesis protein F
NLBNMKHF_01099 9.2e-184 rgpEc GT2 M Glycosyl transferase family 2
NLBNMKHF_01100 5.3e-223 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NLBNMKHF_01101 5.2e-142 rgpC GM Transport permease protein
NLBNMKHF_01102 1e-173 rgpB GT2 M Glycosyltransferase, group 2 family protein
NLBNMKHF_01103 6.1e-213 rgpA GT4 M Domain of unknown function (DUF1972)
NLBNMKHF_01104 1.1e-158 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NLBNMKHF_01105 2.5e-172 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
NLBNMKHF_01106 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
NLBNMKHF_01107 2.3e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NLBNMKHF_01108 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NLBNMKHF_01109 8.9e-44 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NLBNMKHF_01110 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NLBNMKHF_01111 1.9e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
NLBNMKHF_01112 1.1e-211 arcT 2.6.1.1 E Aminotransferase
NLBNMKHF_01113 5.9e-138 ET Belongs to the bacterial solute-binding protein 3 family
NLBNMKHF_01114 6.4e-140 ET ABC transporter
NLBNMKHF_01115 1.3e-84 mutT 3.6.1.55 F Nudix family
NLBNMKHF_01116 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NLBNMKHF_01118 4.9e-168 S CAAX amino terminal protease family protein
NLBNMKHF_01119 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
NLBNMKHF_01120 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
NLBNMKHF_01121 1.7e-17 XK27_00735
NLBNMKHF_01122 6.7e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NLBNMKHF_01124 1.2e-134 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NLBNMKHF_01125 5.7e-10 O ADP-ribosylglycohydrolase
NLBNMKHF_01126 1.9e-62 paaI Q protein possibly involved in aromatic compounds catabolism
NLBNMKHF_01127 6.4e-63 ycaO O OsmC-like protein
NLBNMKHF_01129 1.1e-153 EG Permeases of the drug metabolite transporter (DMT) superfamily
NLBNMKHF_01130 3.2e-07 N PFAM Uncharacterised protein family UPF0150
NLBNMKHF_01131 2.2e-114 serB 3.1.3.3 E phosphoserine phosphatase
NLBNMKHF_01132 6e-305 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NLBNMKHF_01133 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NLBNMKHF_01134 4.2e-98 3.1.3.18 S IA, variant 1
NLBNMKHF_01135 1.6e-115 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NLBNMKHF_01136 3.5e-56 lrgA S Effector of murein hydrolase LrgA
NLBNMKHF_01137 1e-155 S AIPR protein
NLBNMKHF_01138 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NLBNMKHF_01139 1.6e-174 S Helix-hairpin-helix DNA-binding motif class 1
NLBNMKHF_01140 5.5e-106 rimL 2.3.1.128, 5.2.1.8 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NLBNMKHF_01141 1e-107 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NLBNMKHF_01142 3e-14 coiA 3.6.4.12 S Competence protein
NLBNMKHF_01143 2.6e-16 T peptidase
NLBNMKHF_01144 1.1e-148 rarD S Transporter
NLBNMKHF_01145 6.3e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NLBNMKHF_01146 6.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
NLBNMKHF_01147 2.7e-128 yxkH G deacetylase
NLBNMKHF_01148 1.2e-205 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
NLBNMKHF_01149 5.6e-127 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
NLBNMKHF_01150 2.8e-216 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NLBNMKHF_01151 2.7e-188 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NLBNMKHF_01152 2.4e-228 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
NLBNMKHF_01153 1.3e-142 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NLBNMKHF_01154 0.0 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
NLBNMKHF_01156 3e-232 2.7.13.3 T GHKL domain
NLBNMKHF_01157 5.6e-135 agrA KT response regulator
NLBNMKHF_01158 3.1e-07
NLBNMKHF_01159 3e-232 2.7.13.3 T GHKL domain
NLBNMKHF_01160 5.6e-135 agrA KT response regulator
NLBNMKHF_01161 3.1e-07
NLBNMKHF_01162 4.3e-138 agrA KT response regulator
NLBNMKHF_01163 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
NLBNMKHF_01165 1.2e-09
NLBNMKHF_01166 3.5e-59 K sequence-specific DNA binding
NLBNMKHF_01167 5.2e-77 L COG1943 Transposase and inactivated derivatives
NLBNMKHF_01168 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NLBNMKHF_01169 1.7e-84 yxjI S LURP-one-related
NLBNMKHF_01170 7.8e-168 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
NLBNMKHF_01171 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
NLBNMKHF_01172 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
NLBNMKHF_01173 0.0 pepF E oligoendopeptidase F
NLBNMKHF_01174 3.5e-185 coiA 3.6.4.12 S Competence protein
NLBNMKHF_01175 5.2e-78 L transposition
NLBNMKHF_01176 1.3e-55 insK L Integrase core domain protein
NLBNMKHF_01177 7.3e-163 S CHAP domain
NLBNMKHF_01178 2.8e-303 S Glucan-binding protein C
NLBNMKHF_01179 2.7e-105 S CAAX amino terminal protease family protein
NLBNMKHF_01180 4.7e-168 K transcriptional regulator (lysR family)
NLBNMKHF_01181 9.6e-163 S reductase
NLBNMKHF_01182 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NLBNMKHF_01187 2.8e-191 phoH T phosphate starvation-inducible protein PhoH
NLBNMKHF_01188 6e-137 sip M LysM domain protein
NLBNMKHF_01189 3.7e-34 yozE S Belongs to the UPF0346 family
NLBNMKHF_01190 4.5e-160 cvfB S Protein conserved in bacteria
NLBNMKHF_01191 1.7e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NLBNMKHF_01192 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NLBNMKHF_01193 8.5e-213 sptS 2.7.13.3 T Histidine kinase
NLBNMKHF_01194 1.7e-117 T response regulator
NLBNMKHF_01195 8.7e-113 2.7.6.5 S Region found in RelA / SpoT proteins
NLBNMKHF_01196 3.3e-112 K Acetyltransferase (GNAT) family
NLBNMKHF_01197 0.0 lmrA2 V abc transporter atp-binding protein
NLBNMKHF_01198 0.0 lmrA1 V abc transporter atp-binding protein
NLBNMKHF_01199 3.3e-74 K DNA-binding transcription factor activity
NLBNMKHF_01200 4.6e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NLBNMKHF_01201 1.1e-282 S Psort location CytoplasmicMembrane, score
NLBNMKHF_01202 2.8e-257 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
NLBNMKHF_01203 6.3e-215 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
NLBNMKHF_01204 1.8e-128 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
NLBNMKHF_01205 1.7e-26 U response to pH
NLBNMKHF_01206 0.0 yfmR S abc transporter atp-binding protein
NLBNMKHF_01207 9.3e-220 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NLBNMKHF_01208 6.3e-137 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NLBNMKHF_01209 4.2e-150 XK27_08360 S EDD domain protein, DegV family
NLBNMKHF_01210 5e-63 WQ51_03320 S cog cog4835
NLBNMKHF_01211 3.8e-133 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NLBNMKHF_01212 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NLBNMKHF_01213 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
NLBNMKHF_01214 1.7e-93 2.3.1.128 K acetyltransferase
NLBNMKHF_01215 2.8e-254 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NLBNMKHF_01216 1.9e-291 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NLBNMKHF_01217 1.7e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NLBNMKHF_01218 8e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
NLBNMKHF_01220 9.5e-236 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NLBNMKHF_01221 1.1e-256 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NLBNMKHF_01222 0.0 fruA 2.7.1.202 G phosphotransferase system
NLBNMKHF_01223 8.4e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NLBNMKHF_01224 6.8e-112 fruR K transcriptional
NLBNMKHF_01225 7.1e-207 rny D Endoribonuclease that initiates mRNA decay
NLBNMKHF_01226 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NLBNMKHF_01227 1.5e-138 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NLBNMKHF_01228 5e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NLBNMKHF_01229 2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NLBNMKHF_01230 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NLBNMKHF_01231 5.6e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NLBNMKHF_01232 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NLBNMKHF_01233 1.8e-125 IQ reductase
NLBNMKHF_01234 3e-162 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
NLBNMKHF_01235 2e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
NLBNMKHF_01236 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NLBNMKHF_01237 1.1e-170 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NLBNMKHF_01238 5.2e-72 marR K Transcriptional regulator, MarR family
NLBNMKHF_01239 2.1e-140 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
NLBNMKHF_01240 1.6e-117 S HAD hydrolase, family IA, variant 3
NLBNMKHF_01241 1.7e-257 lysC 2.7.2.4 E Belongs to the aspartokinase family
NLBNMKHF_01242 1.4e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
NLBNMKHF_01243 1.5e-247 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NLBNMKHF_01244 2e-138 recX 2.4.1.337 GT4 S Regulatory protein RecX
NLBNMKHF_01245 7.8e-102 ygaC J Belongs to the UPF0374 family
NLBNMKHF_01246 7.3e-104 S Domain of unknown function (DUF1803)
NLBNMKHF_01247 5.6e-164 ppaC 3.6.1.1 C inorganic pyrophosphatase
NLBNMKHF_01255 1.5e-80 hmpT S cog cog4720
NLBNMKHF_01256 4e-136 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
NLBNMKHF_01257 1e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NLBNMKHF_01258 8e-189 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NLBNMKHF_01259 1.7e-103 thiJ-2 3.5.1.124 S DJ-1/PfpI family
NLBNMKHF_01260 6e-303 dnaK O Heat shock 70 kDa protein
NLBNMKHF_01261 5.3e-63 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NLBNMKHF_01262 1.3e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NLBNMKHF_01263 2.7e-100 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
NLBNMKHF_01264 2.3e-142 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
NLBNMKHF_01265 7.3e-132 ais G Phosphoglycerate mutase
NLBNMKHF_01266 2.3e-243 XK27_08635 S UPF0210 protein
NLBNMKHF_01267 6.1e-39 gcvR T UPF0237 protein
NLBNMKHF_01268 8.2e-232 capA M Bacterial capsule synthesis protein
NLBNMKHF_01269 8.5e-140 srtB 3.4.22.70 S sortase, SrtB family
NLBNMKHF_01270 6e-85
NLBNMKHF_01271 1.5e-29 K Helix-turn-helix domain
NLBNMKHF_01272 2e-18
NLBNMKHF_01273 4.5e-55 cadC K Bacterial regulatory protein, arsR family
NLBNMKHF_01274 1.2e-101 cadD P cadmium resistance
NLBNMKHF_01276 6.7e-89 H Methyltransferase
NLBNMKHF_01277 1.7e-89 S Protein conserved in bacteria
NLBNMKHF_01278 7.3e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
NLBNMKHF_01279 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NLBNMKHF_01280 2.7e-20 K Transcriptional
NLBNMKHF_01282 2e-152 degV S DegV family
NLBNMKHF_01283 2.7e-91 yacP S RNA-binding protein containing a PIN domain
NLBNMKHF_01284 2.8e-134 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NLBNMKHF_01286 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NLBNMKHF_01287 8.1e-257 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NLBNMKHF_01289 3.3e-112 cysE 2.3.1.30 E serine acetyltransferase
NLBNMKHF_01290 1.5e-138 S SseB protein N-terminal domain
NLBNMKHF_01291 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NLBNMKHF_01292 3e-229 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NLBNMKHF_01293 2e-233 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NLBNMKHF_01294 0.0 clpC O Belongs to the ClpA ClpB family
NLBNMKHF_01295 4.8e-76 ctsR K Belongs to the CtsR family
NLBNMKHF_01296 1.2e-82 S Putative small multi-drug export protein
NLBNMKHF_01297 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NLBNMKHF_01298 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
NLBNMKHF_01299 1.1e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
NLBNMKHF_01300 8.3e-290 ahpF O alkyl hydroperoxide reductase
NLBNMKHF_01302 2.8e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NLBNMKHF_01303 5e-33 3.4.24.40 U Large extracellular alpha-helical protein
NLBNMKHF_01304 3e-113 L Transposase
NLBNMKHF_01305 8e-38 L Transposase
NLBNMKHF_01306 3e-113 L Transposase
NLBNMKHF_01307 2.6e-68 L Transposase
NLBNMKHF_01308 1.6e-110 L Transposase
NLBNMKHF_01309 3.6e-151 L Transposase
NLBNMKHF_01310 3.1e-173 L Transposase
NLBNMKHF_01311 9.5e-127 L Transposase
NLBNMKHF_01312 1.3e-163 L Transposase
NLBNMKHF_01313 4.3e-161 L Transposase
NLBNMKHF_01315 5.9e-55 bta 1.8.1.8 CO cell redox homeostasis
NLBNMKHF_01316 8.2e-59 L thioesterase
NLBNMKHF_01317 1.3e-142 S Macro domain protein
NLBNMKHF_01318 6.3e-51 trxA O Belongs to the thioredoxin family
NLBNMKHF_01319 2.5e-74 yccU S CoA-binding protein
NLBNMKHF_01320 1.1e-144 tatD L Hydrolase, tatd
NLBNMKHF_01321 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NLBNMKHF_01322 2.9e-154 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NLBNMKHF_01324 6.4e-162 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NLBNMKHF_01325 2.3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NLBNMKHF_01326 1.6e-117 thiN 2.7.6.2 H thiamine pyrophosphokinase
NLBNMKHF_01327 1.6e-169 rmuC S RmuC domain protein
NLBNMKHF_01328 3.1e-178 cbf S 3'-5' exoribonuclease yhaM
NLBNMKHF_01329 4e-142 purR 2.4.2.7 F operon repressor
NLBNMKHF_01330 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NLBNMKHF_01331 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NLBNMKHF_01332 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NLBNMKHF_01333 5.1e-187 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NLBNMKHF_01334 7.1e-14
NLBNMKHF_01335 5.8e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NLBNMKHF_01336 3e-87 S Fusaric acid resistance protein-like
NLBNMKHF_01337 2.5e-62 glnR K Transcriptional regulator
NLBNMKHF_01338 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
NLBNMKHF_01339 6.6e-116 pscB M CHAP domain protein
NLBNMKHF_01340 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NLBNMKHF_01341 1.5e-33 ykzG S Belongs to the UPF0356 family
NLBNMKHF_01342 3.9e-114 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
NLBNMKHF_01343 9e-72 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NLBNMKHF_01344 1.3e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NLBNMKHF_01345 3.9e-114 azlC E AzlC protein
NLBNMKHF_01346 3.7e-46 azlD S branched-chain amino acid
NLBNMKHF_01347 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NLBNMKHF_01348 1.5e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NLBNMKHF_01349 1.3e-154 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NLBNMKHF_01350 9.3e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NLBNMKHF_01351 4.1e-90 cvpA S toxin biosynthetic process
NLBNMKHF_01352 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NLBNMKHF_01353 6e-129 V ABC transporter, ATP-binding protein
NLBNMKHF_01354 2.4e-228 V ABC transporter (Permease
NLBNMKHF_01356 0.0 V ABC transporter (Permease
NLBNMKHF_01357 5.9e-275 2.7.13.3 T Histidine kinase
NLBNMKHF_01358 1.9e-93 salR K helix_turn_helix, Lux Regulon
NLBNMKHF_01359 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NLBNMKHF_01360 1.3e-37
NLBNMKHF_01363 3.4e-227 mutY L A G-specific adenine glycosylase
NLBNMKHF_01364 4.2e-42 XK27_05745
NLBNMKHF_01365 2.3e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
NLBNMKHF_01366 2.5e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NLBNMKHF_01367 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NLBNMKHF_01369 1.3e-122 XK27_01040 S Protein of unknown function (DUF1129)
NLBNMKHF_01370 4.2e-167 corA P COG0598 Mg2 and Co2 transporters
NLBNMKHF_01371 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NLBNMKHF_01375 2.8e-32 blpT
NLBNMKHF_01377 5.4e-187 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
NLBNMKHF_01378 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
NLBNMKHF_01379 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NLBNMKHF_01380 1.7e-61 yqhY S protein conserved in bacteria
NLBNMKHF_01381 8.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NLBNMKHF_01382 4.4e-180 scrR K Transcriptional regulator
NLBNMKHF_01383 5.1e-289 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
NLBNMKHF_01384 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
NLBNMKHF_01385 7e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
NLBNMKHF_01386 3.7e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
NLBNMKHF_01388 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NLBNMKHF_01389 3.3e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NLBNMKHF_01390 5.5e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NLBNMKHF_01391 3.4e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NLBNMKHF_01392 8.8e-201 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NLBNMKHF_01393 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NLBNMKHF_01397 2.9e-31 yozG K Transcriptional regulator
NLBNMKHF_01398 1.2e-280 V ABC transporter transmembrane region
NLBNMKHF_01399 6.8e-156 K Helix-turn-helix XRE-family like proteins
NLBNMKHF_01401 4.6e-177 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NLBNMKHF_01402 1.8e-259 XK27_03190 S hydrolases of the HAD superfamily
NLBNMKHF_01403 2.6e-110 yebC M Membrane
NLBNMKHF_01404 2.2e-307 KT response to antibiotic
NLBNMKHF_01405 5.7e-74 XK27_02470 K LytTr DNA-binding domain
NLBNMKHF_01406 8.2e-120 liaI S membrane
NLBNMKHF_01407 5.6e-77 mccF V LD-carboxypeptidase
NLBNMKHF_01408 4e-43 S Sugar efflux transporter for intercellular exchange
NLBNMKHF_01409 2.6e-194 mccF V LD-carboxypeptidase
NLBNMKHF_01410 9.2e-300 O MreB/Mbl protein
NLBNMKHF_01412 1.3e-145 V Psort location CytoplasmicMembrane, score
NLBNMKHF_01415 8.9e-14
NLBNMKHF_01416 1.1e-242 dcuS 2.7.13.3 T protein histidine kinase activity
NLBNMKHF_01417 8.6e-246 2.7.13.3 T protein histidine kinase activity
NLBNMKHF_01418 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
NLBNMKHF_01419 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NLBNMKHF_01420 2.3e-125 S Protein of unknown function (DUF554)
NLBNMKHF_01421 3.4e-132 ecsA_2 V abc transporter atp-binding protein
NLBNMKHF_01422 2.4e-252 XK27_00765
NLBNMKHF_01423 1.3e-140 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NLBNMKHF_01424 1.1e-199 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NLBNMKHF_01425 3.1e-63 yhaI S Protein of unknown function (DUF805)
NLBNMKHF_01426 5e-69 yhaI J Protein of unknown function (DUF805)
NLBNMKHF_01429 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NLBNMKHF_01430 2.4e-45 ftsL D cell division protein FtsL
NLBNMKHF_01431 0.0 ftsI 3.4.16.4 M penicillin-binding protein
NLBNMKHF_01432 1.7e-182 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NLBNMKHF_01433 7.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NLBNMKHF_01436 1.3e-257 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NLBNMKHF_01437 4.7e-65 yutD J protein conserved in bacteria
NLBNMKHF_01438 1.8e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NLBNMKHF_01439 1.3e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
NLBNMKHF_01442 0.0 mdlA V abc transporter atp-binding protein
NLBNMKHF_01443 0.0 mdlB V abc transporter atp-binding protein
NLBNMKHF_01453 5.2e-07
NLBNMKHF_01454 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NLBNMKHF_01455 2e-163 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
NLBNMKHF_01456 4.5e-107 V CAAX protease self-immunity
NLBNMKHF_01457 1.6e-140 cppA E CppA N-terminal
NLBNMKHF_01458 2.2e-176 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
NLBNMKHF_01460 4.8e-76 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NLBNMKHF_01461 4.4e-146 cah 4.2.1.1 P carbonic anhydrase
NLBNMKHF_01462 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
NLBNMKHF_01464 0.0 pflB 2.3.1.54 C formate acetyltransferase'
NLBNMKHF_01465 3.6e-202 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NLBNMKHF_01466 3.6e-35
NLBNMKHF_01467 3.7e-151 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
NLBNMKHF_01468 8e-163 yxeN P ABC transporter (Permease
NLBNMKHF_01469 1.2e-129 tcyN 3.6.3.21 E abc transporter atp-binding protein
NLBNMKHF_01470 5e-10 S Protein of unknown function (DUF4059)
NLBNMKHF_01471 8e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NLBNMKHF_01472 1.9e-92 rsmD 2.1.1.171 L Methyltransferase
NLBNMKHF_01473 8.6e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NLBNMKHF_01474 4.2e-187 ylbL T Belongs to the peptidase S16 family
NLBNMKHF_01475 8.4e-184 yhcC S radical SAM protein
NLBNMKHF_01476 1e-96 ytqB 2.1.1.176 J (SAM)-dependent
NLBNMKHF_01478 0.0 yjcE P NhaP-type Na H and K H antiporters
NLBNMKHF_01479 8.7e-124 L Transposase
NLBNMKHF_01480 2.1e-143 L Transposase
NLBNMKHF_01481 3.7e-185 L Transposase
NLBNMKHF_01482 4e-154 L Transposase
NLBNMKHF_01483 6.4e-99 L Transposase
NLBNMKHF_01484 2.4e-156 L Transposase
NLBNMKHF_01485 2.4e-159 L Transposase
NLBNMKHF_01486 1.9e-105 L Transposase
NLBNMKHF_01487 1.2e-183 L Transposase
NLBNMKHF_01488 6.9e-87 L Transposase
NLBNMKHF_01489 1.2e-71 L Transposase
NLBNMKHF_01490 9.1e-119 L Transposase
NLBNMKHF_01491 2.2e-242 L Transposase
NLBNMKHF_01492 1.3e-305 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NLBNMKHF_01493 2.2e-219 L the current gene model (or a revised gene model) may contain a frame shift
NLBNMKHF_01494 1.4e-153 Z012_04635 K sequence-specific DNA binding
NLBNMKHF_01495 6.5e-282 V ABC transporter
NLBNMKHF_01496 6.1e-126 yeeN K transcriptional regulatory protein
NLBNMKHF_01497 2.2e-46 yajC U protein transport
NLBNMKHF_01498 5.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NLBNMKHF_01499 9.3e-144 cdsA 2.7.7.41 S Belongs to the CDS family
NLBNMKHF_01500 2.1e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NLBNMKHF_01501 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NLBNMKHF_01502 0.0 WQ51_06230 S ABC transporter
NLBNMKHF_01503 1.4e-142 cmpC S abc transporter atp-binding protein
NLBNMKHF_01504 4.9e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NLBNMKHF_01505 1.5e-286 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NLBNMKHF_01507 1.9e-44
NLBNMKHF_01508 5.8e-55 S TM2 domain
NLBNMKHF_01509 1.3e-159 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NLBNMKHF_01510 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NLBNMKHF_01511 6.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NLBNMKHF_01512 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
NLBNMKHF_01513 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
NLBNMKHF_01514 3e-67 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
NLBNMKHF_01515 1.5e-144 cof S Sucrose-6F-phosphate phosphohydrolase
NLBNMKHF_01516 3e-131 glcR K transcriptional regulator (DeoR family)
NLBNMKHF_01517 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NLBNMKHF_01518 1.4e-72 K transcriptional
NLBNMKHF_01519 8e-227 S COG1073 Hydrolases of the alpha beta superfamily
NLBNMKHF_01520 1.2e-41 yjdF S Protein of unknown function (DUF2992)
NLBNMKHF_01521 6.3e-48 3.2.2.21 S YCII-related domain
NLBNMKHF_01522 3.7e-51 K regulation of RNA biosynthetic process
NLBNMKHF_01523 2.2e-154 cylA V abc transporter atp-binding protein
NLBNMKHF_01524 1.6e-133 cylB V ABC-2 type transporter
NLBNMKHF_01525 2.6e-74 K COG3279 Response regulator of the LytR AlgR family
NLBNMKHF_01526 1.4e-29 S Protein of unknown function (DUF3021)
NLBNMKHF_01527 4.9e-120 mta K Transcriptional
NLBNMKHF_01528 8.1e-120 yhcA V abc transporter atp-binding protein
NLBNMKHF_01529 5.9e-206 macB_2 V FtsX-like permease family
NLBNMKHF_01530 5.7e-272 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NLBNMKHF_01531 1.7e-148 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NLBNMKHF_01532 1.1e-77 yhaI S Protein of unknown function (DUF805)
NLBNMKHF_01533 5.8e-255 pepC 3.4.22.40 E aminopeptidase
NLBNMKHF_01534 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NLBNMKHF_01535 4.3e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NLBNMKHF_01536 5.8e-94 ypsA S Belongs to the UPF0398 family
NLBNMKHF_01537 1.1e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NLBNMKHF_01538 1.3e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NLBNMKHF_01539 4e-284 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
NLBNMKHF_01540 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
NLBNMKHF_01541 9.6e-23
NLBNMKHF_01542 4.7e-257 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NLBNMKHF_01543 4.1e-89 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
NLBNMKHF_01544 6.9e-305 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NLBNMKHF_01545 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NLBNMKHF_01546 3.4e-166 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NLBNMKHF_01547 2e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NLBNMKHF_01548 1e-128 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NLBNMKHF_01549 2.5e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
NLBNMKHF_01550 6.9e-103 ybhL S Belongs to the BI1 family
NLBNMKHF_01551 8.4e-13 ycdA S Domain of unknown function (DUF4352)
NLBNMKHF_01552 2.1e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NLBNMKHF_01553 6.9e-90 K transcriptional regulator
NLBNMKHF_01554 1.6e-36 yneF S UPF0154 protein
NLBNMKHF_01555 1.5e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NLBNMKHF_01556 3.2e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NLBNMKHF_01557 3.9e-98 XK27_09740 S Phosphoesterase
NLBNMKHF_01558 8.3e-87 ykuL S CBS domain
NLBNMKHF_01559 2.7e-132 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
NLBNMKHF_01560 1.8e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NLBNMKHF_01561 6.5e-94 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NLBNMKHF_01562 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NLBNMKHF_01563 1.4e-13 yidD M Could be involved in insertion of integral membrane proteins into the membrane
NLBNMKHF_01564 4.9e-260 trkH P Cation transport protein
NLBNMKHF_01565 1.2e-247 trkA P Potassium transporter peripheral membrane component
NLBNMKHF_01566 6.1e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NLBNMKHF_01567 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NLBNMKHF_01568 2.8e-106 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
NLBNMKHF_01569 1.1e-137 K sequence-specific DNA binding
NLBNMKHF_01570 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NLBNMKHF_01571 6.4e-54 yhaI L Membrane
NLBNMKHF_01572 5.7e-92 S Domain of unknown function (DUF4173)
NLBNMKHF_01573 1.5e-94 ureI S AmiS/UreI family transporter
NLBNMKHF_01574 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
NLBNMKHF_01575 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
NLBNMKHF_01576 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NLBNMKHF_01577 2.5e-77 ureE O enzyme active site formation
NLBNMKHF_01578 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NLBNMKHF_01579 3.6e-111 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NLBNMKHF_01580 1.9e-158 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NLBNMKHF_01581 3.9e-176 cbiM P biosynthesis protein CbiM
NLBNMKHF_01582 1.4e-136 P cobalt transport protein
NLBNMKHF_01583 2.4e-130 cbiO P ABC transporter
NLBNMKHF_01584 6.3e-138 ET ABC transporter substrate-binding protein
NLBNMKHF_01585 1.4e-164 metQ M Belongs to the NlpA lipoprotein family
NLBNMKHF_01586 2e-263 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
NLBNMKHF_01587 2.4e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NLBNMKHF_01588 8e-99 metI P ABC transporter (Permease
NLBNMKHF_01589 9.7e-209 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NLBNMKHF_01590 1.2e-157 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
NLBNMKHF_01591 6.7e-93 S UPF0397 protein
NLBNMKHF_01592 4.3e-308 ykoD P abc transporter atp-binding protein
NLBNMKHF_01593 3.2e-147 cbiQ P cobalt transport
NLBNMKHF_01594 4.8e-117 ktrA P COG0569 K transport systems, NAD-binding component
NLBNMKHF_01595 9.8e-234 P COG0168 Trk-type K transport systems, membrane components
NLBNMKHF_01596 5.5e-127 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
NLBNMKHF_01597 3.1e-90 yceD K metal-binding, possibly nucleic acid-binding protein
NLBNMKHF_01598 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NLBNMKHF_01599 3.2e-281 T PhoQ Sensor
NLBNMKHF_01600 1.4e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NLBNMKHF_01601 3.6e-216 dnaB L Replication initiation and membrane attachment
NLBNMKHF_01602 1.5e-166 dnaI L Primosomal protein DnaI
NLBNMKHF_01603 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NLBNMKHF_01604 1e-113
NLBNMKHF_01605 1.4e-229 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NLBNMKHF_01606 2.5e-62 manO S protein conserved in bacteria
NLBNMKHF_01607 3.3e-169 manN G PTS system mannose fructose sorbose family IID component
NLBNMKHF_01608 1.2e-117 manM G pts system
NLBNMKHF_01609 4e-176 manL 2.7.1.191 G pts system
NLBNMKHF_01610 1e-66 manO S Protein conserved in bacteria
NLBNMKHF_01611 2.8e-160 manN G PTS system mannose fructose sorbose family IID component
NLBNMKHF_01612 4.8e-132 manY G pts system
NLBNMKHF_01613 2.4e-168 manL 2.7.1.191 G pts system
NLBNMKHF_01614 3.2e-138 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
NLBNMKHF_01615 3.5e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
NLBNMKHF_01616 3.6e-247 pbuO S permease
NLBNMKHF_01617 4.7e-76 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
NLBNMKHF_01618 6e-91 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
NLBNMKHF_01619 4.4e-188 brpA K Transcriptional
NLBNMKHF_01620 2.3e-81 rimP S Required for maturation of 30S ribosomal subunits
NLBNMKHF_01621 2.4e-196 nusA K Participates in both transcription termination and antitermination
NLBNMKHF_01622 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
NLBNMKHF_01623 8e-42 ylxQ J ribosomal protein
NLBNMKHF_01624 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NLBNMKHF_01625 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NLBNMKHF_01626 2.9e-99 yvdD 3.2.2.10 S Belongs to the LOG family
NLBNMKHF_01627 1.9e-272 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NLBNMKHF_01628 1.3e-282 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
NLBNMKHF_01629 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
NLBNMKHF_01630 5.1e-201 metB 2.5.1.48, 4.4.1.8 E cystathionine
NLBNMKHF_01631 1.5e-222 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NLBNMKHF_01632 0.0 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
NLBNMKHF_01633 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
NLBNMKHF_01634 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NLBNMKHF_01635 3.7e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NLBNMKHF_01636 9.8e-74 ylbF S Belongs to the UPF0342 family
NLBNMKHF_01637 1.9e-46 ylbG S UPF0298 protein
NLBNMKHF_01638 1.4e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
NLBNMKHF_01639 4.2e-145 livH E Belongs to the binding-protein-dependent transport system permease family
NLBNMKHF_01640 8.3e-139 livM E Belongs to the binding-protein-dependent transport system permease family
NLBNMKHF_01641 2.4e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
NLBNMKHF_01642 5.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
NLBNMKHF_01643 7.1e-113 acuB S CBS domain
NLBNMKHF_01644 6.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NLBNMKHF_01645 3.2e-107 yvyE 3.4.13.9 S YigZ family
NLBNMKHF_01646 7.5e-247 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NLBNMKHF_01647 1e-82 comFC K competence protein
NLBNMKHF_01648 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NLBNMKHF_01649 6.4e-79 tcyB_2 P ABC transporter (permease)
NLBNMKHF_01650 4.5e-57 gltJ P ABC transporter (Permease
NLBNMKHF_01651 2.5e-133 L Transposase
NLBNMKHF_01652 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
NLBNMKHF_01653 1.2e-227 S dextransucrase activity
NLBNMKHF_01655 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
NLBNMKHF_01656 1.5e-116 yhfC S Putative membrane peptidase family (DUF2324)
NLBNMKHF_01657 4.2e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
NLBNMKHF_01658 1e-14 S integral membrane protein
NLBNMKHF_01659 1.3e-190 mccF V LD-carboxypeptidase
NLBNMKHF_01660 2.4e-08 S Enterocin A Immunity
NLBNMKHF_01661 0.0 pepO 3.4.24.71 O Peptidase family M13
NLBNMKHF_01662 4.1e-34 S Immunity protein 41
NLBNMKHF_01663 0.0 M Putative cell wall binding repeat
NLBNMKHF_01664 2.8e-227 thrE K Psort location CytoplasmicMembrane, score
NLBNMKHF_01665 1.7e-179 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
NLBNMKHF_01666 4.5e-95 dhaL 2.7.1.121 S Dihydroxyacetone kinase
NLBNMKHF_01667 6.3e-58 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
NLBNMKHF_01668 1e-176 XK27_10475 S oxidoreductase
NLBNMKHF_01669 9.7e-200 gldA 1.1.1.6 C glycerol dehydrogenase
NLBNMKHF_01671 1.2e-282 XK27_07020 S Belongs to the UPF0371 family
NLBNMKHF_01672 5.3e-210 vex1 V Efflux ABC transporter, permease protein
NLBNMKHF_01673 1.9e-107 vex2 V abc transporter atp-binding protein
NLBNMKHF_01674 7.8e-239 vex3 V Efflux ABC transporter, permease protein
NLBNMKHF_01675 2e-115 K Response regulator receiver domain protein
NLBNMKHF_01676 2.9e-227 vncS 2.7.13.3 T Histidine kinase
NLBNMKHF_01677 3.9e-306 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
NLBNMKHF_01678 2e-175 galR K Transcriptional regulator
NLBNMKHF_01679 5.6e-222 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NLBNMKHF_01680 6.5e-287 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
NLBNMKHF_01681 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NLBNMKHF_01682 4.2e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NLBNMKHF_01683 0.0 lacS G transporter
NLBNMKHF_01684 0.0 lacL 3.2.1.23 G -beta-galactosidase
NLBNMKHF_01685 1.4e-209 S Tetratricopeptide repeat
NLBNMKHF_01686 1.2e-157 yvgN C reductase
NLBNMKHF_01687 3.2e-30 XK27_10490
NLBNMKHF_01688 7.6e-39 DJ nuclease activity
NLBNMKHF_01689 1.6e-107 yoaK S Protein of unknown function (DUF1275)
NLBNMKHF_01690 4.1e-110 drgA C nitroreductase
NLBNMKHF_01691 2.1e-123 T Xre family transcriptional regulator
NLBNMKHF_01692 3.4e-147 T PhoQ Sensor
NLBNMKHF_01693 4.3e-45 S Domain of unknown function (DUF4352)
NLBNMKHF_01694 6.8e-128 S ABC-2 family transporter protein
NLBNMKHF_01695 1.7e-168 bcrA V abc transporter atp-binding protein
NLBNMKHF_01696 1.2e-225 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NLBNMKHF_01697 4.9e-154 E Alpha/beta hydrolase of unknown function (DUF915)
NLBNMKHF_01698 4.7e-76 ywnA K Transcriptional regulator
NLBNMKHF_01699 1.5e-152 1.13.11.2 S glyoxalase
NLBNMKHF_01700 2.2e-108 XK27_02070 S nitroreductase
NLBNMKHF_01701 1.3e-35
NLBNMKHF_01702 5.5e-27 XK27_07105 K transcriptional
NLBNMKHF_01703 1.1e-09 S Protein of unknown function (DUF3169)
NLBNMKHF_01704 9.8e-166 natA S abc transporter atp-binding protein
NLBNMKHF_01705 2.1e-211 natB CP ABC-type Na efflux pump, permease component
NLBNMKHF_01706 1.2e-169 ydhF S Aldo keto reductase
NLBNMKHF_01707 4e-96 K WHG domain
NLBNMKHF_01708 3.9e-122 V abc transporter atp-binding protein
NLBNMKHF_01709 4.4e-203 P FtsX-like permease family
NLBNMKHF_01710 1.5e-42 S Sugar efflux transporter for intercellular exchange
NLBNMKHF_01711 1.1e-83 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
NLBNMKHF_01712 2.9e-174 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
NLBNMKHF_01713 6.1e-165 ET ABC transporter substrate-binding protein
NLBNMKHF_01714 1.3e-109 ytmL P ABC transporter (Permease
NLBNMKHF_01715 4.3e-113 yxeN P ABC transporter, permease protein
NLBNMKHF_01716 4.3e-138 tcyC2 3.6.3.21 E abc transporter atp-binding protein
NLBNMKHF_01717 0.0 S dextransucrase activity
NLBNMKHF_01718 7.2e-216 yfnA E amino acid
NLBNMKHF_01719 3e-51 XK27_01300 S ASCH
NLBNMKHF_01720 3e-122 S Carbohydrate-binding domain-containing protein Cthe_2159
NLBNMKHF_01721 1.4e-16 csbD S CsbD-like
NLBNMKHF_01722 1.5e-107 S Protein of unknown function (DUF421)
NLBNMKHF_01723 1.8e-59 S Protein of unknown function (DUF3290)
NLBNMKHF_01724 1e-181 manA 5.3.1.8 G mannose-6-phosphate isomerase
NLBNMKHF_01725 8.9e-232 brnQ E Component of the transport system for branched-chain amino acids
NLBNMKHF_01726 2e-180 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NLBNMKHF_01728 8.7e-243 norM V Multidrug efflux pump
NLBNMKHF_01729 2.6e-152 K sequence-specific DNA binding
NLBNMKHF_01730 1.2e-270 V (ABC) transporter
NLBNMKHF_01731 4.5e-59 pdxH S pyridoxamine 5'-phosphate oxidase
NLBNMKHF_01732 3.8e-224 pbuX F xanthine permease
NLBNMKHF_01733 2.5e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NLBNMKHF_01734 5.4e-124 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NLBNMKHF_01735 2.2e-147 T Histidine kinase
NLBNMKHF_01736 1.1e-133 macB2 V ABC transporter, ATP-binding protein
NLBNMKHF_01737 0.0 V ABC transporter (permease)
NLBNMKHF_01738 2.3e-92 XK27_05000 S metal cluster binding
NLBNMKHF_01739 2.2e-29 liaI KT membrane
NLBNMKHF_01740 3.7e-16 liaI KT membrane
NLBNMKHF_01741 9.7e-158 XK27_09825 V abc transporter atp-binding protein
NLBNMKHF_01742 1.7e-115 yvfS V Transporter
NLBNMKHF_01743 3.1e-83 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
NLBNMKHF_01744 3.3e-164 yocS S Transporter
NLBNMKHF_01747 6.7e-159 XK27_09825 V 'abc transporter, ATP-binding protein
NLBNMKHF_01748 5.3e-133 yvfS V ABC-2 type transporter
NLBNMKHF_01749 3.2e-187 desK 2.7.13.3 T Histidine kinase
NLBNMKHF_01750 3.9e-102 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NLBNMKHF_01751 4.5e-203 S Protein of unknown function DUF262
NLBNMKHF_01752 3.9e-125 S Protein of unknown function DUF262
NLBNMKHF_01753 7.3e-85 yfjR K regulation of single-species biofilm formation
NLBNMKHF_01756 9e-116
NLBNMKHF_01757 7.4e-30
NLBNMKHF_01759 2.3e-24
NLBNMKHF_01760 1.7e-88
NLBNMKHF_01761 7.5e-49
NLBNMKHF_01762 1.3e-80 3.4.21.89 S RDD family
NLBNMKHF_01763 6.7e-162 yjlA EG membrane
NLBNMKHF_01764 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
NLBNMKHF_01765 3.4e-147 sdaAA 4.3.1.17 E L-serine dehydratase
NLBNMKHF_01766 8.8e-119 sdaAB 4.3.1.17 E L-serine dehydratase
NLBNMKHF_01767 2.8e-128 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
NLBNMKHF_01768 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NLBNMKHF_01769 9.4e-272 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NLBNMKHF_01770 1.1e-92 pat 2.3.1.183 M acetyltransferase
NLBNMKHF_01771 1.5e-299 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NLBNMKHF_01772 1.8e-124 alkD L Dna alkylation repair
NLBNMKHF_01773 1.6e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NLBNMKHF_01774 1.7e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NLBNMKHF_01775 2.5e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NLBNMKHF_01776 0.0 smc D Required for chromosome condensation and partitioning
NLBNMKHF_01777 1e-93 S Protein of unknown function (DUF3278)
NLBNMKHF_01778 2.9e-22 WQ51_00220 K Helix-turn-helix domain
NLBNMKHF_01779 6.6e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NLBNMKHF_01780 8.4e-93 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NLBNMKHF_01781 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NLBNMKHF_01783 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
NLBNMKHF_01784 2.5e-161 L PFAM Integrase, catalytic core
NLBNMKHF_01785 6.6e-135 L Transposase
NLBNMKHF_01786 2.4e-58 L PFAM Integrase, catalytic core
NLBNMKHF_01787 3.2e-149 L PFAM Integrase, catalytic core
NLBNMKHF_01788 9.1e-124 L PFAM Integrase, catalytic core
NLBNMKHF_01789 9.8e-60 L PFAM Integrase, catalytic core
NLBNMKHF_01790 2.4e-58 L PFAM Integrase, catalytic core
NLBNMKHF_01791 2.6e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NLBNMKHF_01792 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NLBNMKHF_01794 2.8e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NLBNMKHF_01795 9.6e-158 holB 2.7.7.7 L dna polymerase iii
NLBNMKHF_01796 8.9e-134 yaaT S stage 0 sporulation protein
NLBNMKHF_01797 1.2e-54 yabA L Involved in initiation control of chromosome replication
NLBNMKHF_01798 4e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NLBNMKHF_01799 1.9e-228 amt P Ammonium Transporter
NLBNMKHF_01800 1.9e-53 glnB K Belongs to the P(II) protein family
NLBNMKHF_01801 1.6e-104 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
NLBNMKHF_01802 1.7e-108 S HD domain
NLBNMKHF_01803 7e-147 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
NLBNMKHF_01804 5.6e-84 S Bacterial inner membrane protein
NLBNMKHF_01805 3.7e-111 3.4.17.14, 3.5.1.28 NU amidase activity
NLBNMKHF_01806 7.2e-292 nptA P COG1283 Na phosphate symporter
NLBNMKHF_01807 2.6e-211 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NLBNMKHF_01808 5.6e-220 S membrane
NLBNMKHF_01809 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NLBNMKHF_01810 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NLBNMKHF_01811 2e-39 ynzC S UPF0291 protein
NLBNMKHF_01812 1.2e-255 cycA E permease
NLBNMKHF_01813 6e-08 uvrX 2.7.7.7 L impB/mucB/samB family
NLBNMKHF_01814 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
NLBNMKHF_01815 9.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NLBNMKHF_01818 3.4e-69 K Helix-turn-helix
NLBNMKHF_01820 4.7e-168 fhuR K transcriptional regulator (lysR family)
NLBNMKHF_01821 4.8e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NLBNMKHF_01822 1.1e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NLBNMKHF_01823 4.8e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NLBNMKHF_01824 3.6e-222 pyrP F uracil Permease
NLBNMKHF_01825 1.3e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NLBNMKHF_01826 9.3e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
NLBNMKHF_01827 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
NLBNMKHF_01828 2.3e-128 2.1.1.223 S Putative SAM-dependent methyltransferase
NLBNMKHF_01829 3.6e-182 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NLBNMKHF_01830 2.9e-120 macB V ABC transporter, ATP-binding protein
NLBNMKHF_01831 1.2e-211 V permease protein
NLBNMKHF_01832 1.9e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NLBNMKHF_01833 2.1e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NLBNMKHF_01835 2.5e-273 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
NLBNMKHF_01836 0.0 mdlB V abc transporter atp-binding protein
NLBNMKHF_01837 0.0 lmrA V abc transporter atp-binding protein
NLBNMKHF_01838 2.1e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NLBNMKHF_01839 2e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NLBNMKHF_01840 5.3e-213 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
NLBNMKHF_01841 1.2e-129 rr02 KT response regulator
NLBNMKHF_01842 5.7e-219 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NLBNMKHF_01843 9.3e-164 V ABC transporter
NLBNMKHF_01844 3.3e-119 sagI S ABC-2 type transporter
NLBNMKHF_01845 7.6e-196 yceA S Belongs to the UPF0176 family
NLBNMKHF_01846 2.3e-27 XK27_00085 K Transcriptional
NLBNMKHF_01847 2.1e-24
NLBNMKHF_01848 4.2e-133 deoD_1 2.4.2.3 F Phosphorylase superfamily
NLBNMKHF_01849 3.9e-114 S VIT family
NLBNMKHF_01850 7.2e-127 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NLBNMKHF_01851 7e-217 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NLBNMKHF_01852 2.2e-199 ald 1.4.1.1 C Belongs to the AlaDH PNT family
NLBNMKHF_01855 4.9e-140 E Alpha beta hydrolase
NLBNMKHF_01856 5.2e-248 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NLBNMKHF_01857 2e-120 L PFAM Integrase, catalytic core
NLBNMKHF_01858 0.0 M family 8
NLBNMKHF_01859 4e-113 cutC P Participates in the control of copper homeostasis
NLBNMKHF_01860 1.4e-129 S CAAX amino terminal protease family
NLBNMKHF_01861 6.3e-94 ypgQ F HD superfamily hydrolase
NLBNMKHF_01862 2e-95 XK27_08140 K Bacterial regulatory proteins, tetR family
NLBNMKHF_01863 7.1e-150 yitS S EDD domain protein, DegV family
NLBNMKHF_01864 1e-199 yeaN P transporter
NLBNMKHF_01865 4.7e-138 L Transposase and inactivated derivatives
NLBNMKHF_01866 5.3e-74 L Transposase
NLBNMKHF_01867 3e-75 XK27_04435 3.5.4.5 J Acetyltransferase GNAT family
NLBNMKHF_01868 5.9e-40 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NLBNMKHF_01869 2e-158 K DNA-binding helix-turn-helix protein
NLBNMKHF_01870 1.2e-138 S CAAX protease self-immunity
NLBNMKHF_01871 4.3e-138 S Alpha beta hydrolase
NLBNMKHF_01872 2.7e-64
NLBNMKHF_01873 5e-54 D Plasmid stabilization system
NLBNMKHF_01874 2.2e-45
NLBNMKHF_01875 1.8e-147 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NLBNMKHF_01876 2e-58 S ParE toxin of type II toxin-antitoxin system, parDE
NLBNMKHF_01877 4.8e-45
NLBNMKHF_01878 0.0 O Molecular chaperone. Has ATPase activity
NLBNMKHF_01879 1.8e-256 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NLBNMKHF_01880 2e-97 mip S hydroperoxide reductase activity
NLBNMKHF_01881 2.2e-201 I acyl-CoA dehydrogenase
NLBNMKHF_01882 1.7e-152 ydiA P C4-dicarboxylate transporter malic acid transport
NLBNMKHF_01883 1.7e-244 msrR K Transcriptional regulator
NLBNMKHF_01884 2.5e-152 pheA 4.2.1.51 E Prephenate dehydratase
NLBNMKHF_01885 6.7e-76 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NLBNMKHF_01886 3.7e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NLBNMKHF_01887 2.4e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NLBNMKHF_01888 4.2e-53 yheA S Belongs to the UPF0342 family
NLBNMKHF_01889 8.3e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
NLBNMKHF_01890 9.9e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NLBNMKHF_01891 5.9e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NLBNMKHF_01892 3.5e-160 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NLBNMKHF_01893 2.1e-120 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NLBNMKHF_01894 1.4e-217 ywbD 2.1.1.191 J Methyltransferase
NLBNMKHF_01895 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NLBNMKHF_01896 4.6e-25 WQ51_00785
NLBNMKHF_01897 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NLBNMKHF_01898 3.4e-74 yueI S Protein of unknown function (DUF1694)
NLBNMKHF_01899 4e-193 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NLBNMKHF_01900 6.6e-193 yyaQ S YjbR
NLBNMKHF_01901 4.1e-181 ccpA K Catabolite control protein A
NLBNMKHF_01902 1.4e-195 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
NLBNMKHF_01903 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
NLBNMKHF_01904 2e-274 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NLBNMKHF_01905 6.6e-81 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NLBNMKHF_01906 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NLBNMKHF_01907 2e-33 secG U Preprotein translocase subunit SecG
NLBNMKHF_01908 2.2e-221 mdtG EGP Major facilitator Superfamily
NLBNMKHF_01909 5.1e-102 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NLBNMKHF_01910 6.9e-150 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NLBNMKHF_01911 2.2e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NLBNMKHF_01912 2e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NLBNMKHF_01913 4.6e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NLBNMKHF_01914 4.6e-149 licT K antiterminator
NLBNMKHF_01915 1.3e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NLBNMKHF_01916 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
NLBNMKHF_01917 1.1e-145 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NLBNMKHF_01918 4.3e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NLBNMKHF_01919 2.9e-150 I Alpha/beta hydrolase family
NLBNMKHF_01920 6.6e-08
NLBNMKHF_01921 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
NLBNMKHF_01922 1.4e-78 feoA P FeoA domain protein
NLBNMKHF_01923 6.4e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
NLBNMKHF_01924 5.8e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
NLBNMKHF_01925 1e-34 ykuJ S protein conserved in bacteria
NLBNMKHF_01926 1.4e-181 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NLBNMKHF_01927 0.0 clpE O Belongs to the ClpA ClpB family
NLBNMKHF_01928 1.2e-82 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
NLBNMKHF_01929 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
NLBNMKHF_01930 1.3e-171 S oxidoreductase
NLBNMKHF_01931 9.3e-81 M Pfam SNARE associated Golgi protein
NLBNMKHF_01932 4.1e-77 L Integrase
NLBNMKHF_01933 9e-139 ykuT M mechanosensitive ion channel
NLBNMKHF_01934 5.2e-229 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NLBNMKHF_01935 1e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NLBNMKHF_01936 5.8e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NLBNMKHF_01937 3.8e-84 XK27_03960 S Protein of unknown function (DUF3013)
NLBNMKHF_01938 1.1e-77 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
NLBNMKHF_01939 2.5e-83 XK27_02675 K Acetyltransferase GNAT Family
NLBNMKHF_01940 2.6e-177 prmA J Ribosomal protein L11 methyltransferase
NLBNMKHF_01941 3.4e-132 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NLBNMKHF_01942 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NLBNMKHF_01943 9.1e-83 nrdI F Belongs to the NrdI family
NLBNMKHF_01944 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NLBNMKHF_01945 2.8e-73 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NLBNMKHF_01946 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
NLBNMKHF_01947 8.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NLBNMKHF_01948 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NLBNMKHF_01949 1.3e-111 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
NLBNMKHF_01950 2.9e-194 yhjX P Major Facilitator
NLBNMKHF_01951 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NLBNMKHF_01952 5.4e-72 V VanZ like family
NLBNMKHF_01953 1.8e-180 D nuclear chromosome segregation
NLBNMKHF_01955 2.8e-17 KT phosphorelay signal transduction system
NLBNMKHF_01956 1.8e-120 agrA KT response regulator
NLBNMKHF_01957 2.1e-148 comD 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
NLBNMKHF_01958 1.9e-53
NLBNMKHF_01960 8.5e-11
NLBNMKHF_01961 1.6e-128 V ABC transporter
NLBNMKHF_01962 1e-49
NLBNMKHF_01963 2.2e-123 glnQ E abc transporter atp-binding protein
NLBNMKHF_01964 5.5e-273 glnP P ABC transporter
NLBNMKHF_01965 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NLBNMKHF_01966 6.3e-18 S Protein of unknown function (DUF3021)
NLBNMKHF_01967 2e-124 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NLBNMKHF_01968 3e-183 tagO 2.7.8.33, 2.7.8.35 M transferase
NLBNMKHF_01969 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NLBNMKHF_01970 1.2e-233 sufD O assembly protein SufD
NLBNMKHF_01971 2.8e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NLBNMKHF_01972 9.4e-74 nifU C SUF system FeS assembly protein, NifU family
NLBNMKHF_01973 2.9e-273 sufB O assembly protein SufB
NLBNMKHF_01974 2.7e-26
NLBNMKHF_01975 4e-156 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NLBNMKHF_01976 2.8e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NLBNMKHF_01977 2e-71 adcR K transcriptional
NLBNMKHF_01978 2.4e-135 adcC P ABC transporter, ATP-binding protein
NLBNMKHF_01979 3.9e-129 adcB P ABC transporter (Permease
NLBNMKHF_01980 2.9e-160 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
NLBNMKHF_01981 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
NLBNMKHF_01982 4.6e-154 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
NLBNMKHF_01983 4.2e-253 pgi 5.3.1.9 G Belongs to the GPI family
NLBNMKHF_01984 1.4e-142 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NLBNMKHF_01985 0.0 srlM 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
NLBNMKHF_01986 6.8e-84 gutM K phosphoenolpyruvate-dependent sugar phosphotransferase system
NLBNMKHF_01987 1.1e-95 srlA G PTS system glucitol sorbitol-specific
NLBNMKHF_01988 3.8e-179 srlE 2.7.1.198 G PTS sorbitol transporter subunit IIB
NLBNMKHF_01989 4.2e-59 srlB 2.7.1.198 G sorbitol-specific, IIA component
NLBNMKHF_01990 9.2e-59 L MULE transposase domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)