ORF_ID e_value Gene_name EC_number CAZy COGs Description
EONCEDMH_00005 2.7e-23
EONCEDMH_00006 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
EONCEDMH_00007 0.0 3.5.1.28 M domain protein
EONCEDMH_00008 2.9e-88 V abc transporter atp-binding protein
EONCEDMH_00009 2.4e-14
EONCEDMH_00011 2.3e-74 K Transcriptional regulatory protein, C terminal
EONCEDMH_00012 1.2e-64 2.7.13.3 T Histidine kinase
EONCEDMH_00013 1.5e-90 maa 2.3.1.79 GK Maltose O-acetyltransferase
EONCEDMH_00014 9.3e-63 rmaI K Transcriptional regulator, MarR family
EONCEDMH_00015 1.4e-213 EGP Major facilitator Superfamily
EONCEDMH_00016 4.6e-108 XK27_00785 S CAAX protease self-immunity
EONCEDMH_00017 5.1e-119 mleR K malolactic fermentation system
EONCEDMH_00018 4.7e-47 K Helix-turn-helix
EONCEDMH_00019 4.5e-311 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme, NAD binding domain
EONCEDMH_00020 1.4e-159 mleP S Sodium Bile acid symporter family
EONCEDMH_00021 1.9e-91 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EONCEDMH_00023 1.1e-219 S dextransucrase activity
EONCEDMH_00024 0.0 S dextransucrase activity
EONCEDMH_00025 6.4e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EONCEDMH_00026 8.1e-233 vicK 2.7.13.3 T Histidine kinase
EONCEDMH_00027 1e-153 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
EONCEDMH_00028 1.5e-56 S Protein of unknown function (DUF454)
EONCEDMH_00029 6.7e-226 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
EONCEDMH_00030 7.8e-146 yidA S hydrolases of the HAD superfamily
EONCEDMH_00031 1.4e-137 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
EONCEDMH_00032 5.1e-131 XK27_00120 2.4.2.3 F Phosphorylase superfamily
EONCEDMH_00033 1.2e-67 ywiB S Domain of unknown function (DUF1934)
EONCEDMH_00034 0.0 pacL 3.6.3.8 P cation transport ATPase
EONCEDMH_00035 3.6e-129 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
EONCEDMH_00036 1.8e-153 yjjH S Calcineurin-like phosphoesterase
EONCEDMH_00037 3.5e-205 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EONCEDMH_00038 2.1e-182 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EONCEDMH_00039 3.2e-124 ftsE D cell division ATP-binding protein FtsE
EONCEDMH_00040 7.3e-164 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
EONCEDMH_00041 6.6e-92 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
EONCEDMH_00042 1.2e-176 yubA S permease
EONCEDMH_00043 8.5e-221 G COG0457 FOG TPR repeat
EONCEDMH_00044 2.5e-95 lepB 3.4.21.89 U Belongs to the peptidase S26 family
EONCEDMH_00045 6.1e-175 S dextransucrase activity
EONCEDMH_00046 7.9e-64 glnQ 3.6.3.21 E abc transporter atp-binding protein
EONCEDMH_00047 2.3e-145 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
EONCEDMH_00048 8.4e-66 glnQ 3.6.3.21 E abc transporter atp-binding protein
EONCEDMH_00056 6.8e-162 ppaC 3.6.1.1 C inorganic pyrophosphatase
EONCEDMH_00057 2e-101 S Domain of unknown function (DUF1803)
EONCEDMH_00058 7.8e-102 ygaC J Belongs to the UPF0374 family
EONCEDMH_00059 5.2e-131 recX 2.4.1.337 GT4 S Regulatory protein RecX
EONCEDMH_00060 2.9e-246 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EONCEDMH_00061 1.4e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
EONCEDMH_00062 1.7e-257 lysC 2.7.2.4 E Belongs to the aspartokinase family
EONCEDMH_00063 6e-117 S HAD hydrolase, family IA, variant 3
EONCEDMH_00064 6.2e-140 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
EONCEDMH_00065 1.3e-70 marR K Transcriptional regulator, MarR family
EONCEDMH_00066 1.9e-170 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EONCEDMH_00067 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
EONCEDMH_00068 9.9e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
EONCEDMH_00069 6.7e-162 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
EONCEDMH_00070 8.1e-126 IQ reductase
EONCEDMH_00071 9.8e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EONCEDMH_00072 3.3e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EONCEDMH_00073 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EONCEDMH_00074 8.3e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
EONCEDMH_00075 2.7e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EONCEDMH_00076 3.9e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
EONCEDMH_00077 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EONCEDMH_00078 7.1e-207 rny D Endoribonuclease that initiates mRNA decay
EONCEDMH_00079 5.9e-124 fruR K transcriptional
EONCEDMH_00080 7.6e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
EONCEDMH_00081 0.0 fruA 2.7.1.202 G phosphotransferase system
EONCEDMH_00082 5.3e-256 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EONCEDMH_00083 1.9e-223 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
EONCEDMH_00085 4.4e-211 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
EONCEDMH_00086 2.8e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EONCEDMH_00087 4.3e-291 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
EONCEDMH_00088 4.1e-253 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
EONCEDMH_00089 5.3e-82 2.3.1.128 K acetyltransferase
EONCEDMH_00090 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
EONCEDMH_00091 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
EONCEDMH_00092 1.6e-131 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EONCEDMH_00093 5e-63 WQ51_03320 S cog cog4835
EONCEDMH_00094 2.8e-146 XK27_08360 S EDD domain protein, DegV family
EONCEDMH_00095 2.5e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EONCEDMH_00096 2.5e-217 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EONCEDMH_00097 0.0 yfmR S abc transporter atp-binding protein
EONCEDMH_00098 1.7e-26 U response to pH
EONCEDMH_00099 3.7e-129 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
EONCEDMH_00100 3.6e-210 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
EONCEDMH_00101 1.4e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
EONCEDMH_00102 5.2e-266 S Psort location CytoplasmicMembrane, score
EONCEDMH_00103 7.9e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
EONCEDMH_00104 1.4e-72 K DNA-binding transcription factor activity
EONCEDMH_00105 1.1e-309 lmrA1 V abc transporter atp-binding protein
EONCEDMH_00106 0.0 lmrA2 V abc transporter atp-binding protein
EONCEDMH_00107 1.3e-108 K Acetyltransferase (GNAT) family
EONCEDMH_00108 2.8e-111 2.7.6.5 S Region found in RelA / SpoT proteins
EONCEDMH_00109 6e-115 T response regulator
EONCEDMH_00110 1.8e-210 sptS 2.7.13.3 T Histidine kinase
EONCEDMH_00111 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
EONCEDMH_00112 1.7e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EONCEDMH_00113 4.2e-158 cvfB S Protein conserved in bacteria
EONCEDMH_00114 3.7e-34 yozE S Belongs to the UPF0346 family
EONCEDMH_00115 9.4e-130 sip M LysM domain protein
EONCEDMH_00116 2.4e-187 phoH T phosphate starvation-inducible protein PhoH
EONCEDMH_00120 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EONCEDMH_00121 1.1e-101 L DNA synthesis involved in DNA repair
EONCEDMH_00122 5.8e-07 V HNH endonuclease
EONCEDMH_00123 1.6e-155 L the current gene model (or a revised gene model) may contain a frame shift
EONCEDMH_00124 2.4e-161 S reductase
EONCEDMH_00125 4.7e-168 K transcriptional regulator (lysR family)
EONCEDMH_00126 5.9e-108 S CAAX amino terminal protease family protein
EONCEDMH_00127 1.8e-273 S Glucan-binding protein C
EONCEDMH_00128 1e-165 coiA 3.6.4.12 S Competence protein
EONCEDMH_00129 0.0 pepF E oligoendopeptidase F
EONCEDMH_00130 6.5e-213 oxlT P COG0477 Permeases of the major facilitator superfamily
EONCEDMH_00131 6.1e-120 yrrM 2.1.1.104 S O-Methyltransferase
EONCEDMH_00132 1.1e-166 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
EONCEDMH_00133 1e-84 yxjI S LURP-one-related
EONCEDMH_00134 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EONCEDMH_00137 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
EONCEDMH_00138 1.4e-133 agrA KT phosphorelay signal transduction system
EONCEDMH_00139 6.6e-227 2.7.13.3 T GHKL domain
EONCEDMH_00140 9.8e-245 3.5.1.28 NU GBS Bsp-like repeat
EONCEDMH_00142 0.0 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
EONCEDMH_00143 4e-139 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EONCEDMH_00144 3e-223 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
EONCEDMH_00145 2.6e-183 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EONCEDMH_00146 5.6e-217 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EONCEDMH_00147 3.2e-122 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
EONCEDMH_00148 5.3e-201 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
EONCEDMH_00149 2.1e-136 yxkH G deacetylase
EONCEDMH_00150 2.6e-236 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
EONCEDMH_00151 2.2e-151 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EONCEDMH_00152 5.7e-150 rarD S Transporter
EONCEDMH_00153 1.7e-15 T peptidase
EONCEDMH_00154 3e-14 coiA 3.6.4.12 S Competence protein
EONCEDMH_00157 1.6e-100 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EONCEDMH_00158 7.1e-98 2.3.1.128, 5.2.1.8 J Acetyltransferase (GNAT) domain
EONCEDMH_00159 1.5e-15
EONCEDMH_00160 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EONCEDMH_00161 1.3e-291 S AAA ATPase domain
EONCEDMH_00162 2.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EONCEDMH_00163 9e-122 atpB C it plays a direct role in the translocation of protons across the membrane
EONCEDMH_00164 2.1e-61 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EONCEDMH_00165 1e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EONCEDMH_00166 8.4e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EONCEDMH_00167 6.2e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EONCEDMH_00168 2.3e-262 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EONCEDMH_00169 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
EONCEDMH_00170 2.7e-217 ftsW D Belongs to the SEDS family
EONCEDMH_00171 1.6e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EONCEDMH_00172 2.6e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EONCEDMH_00173 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EONCEDMH_00175 1e-108 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EONCEDMH_00176 3.3e-158 holB 2.7.7.7 L dna polymerase iii
EONCEDMH_00177 4.4e-133 yaaT S stage 0 sporulation protein
EONCEDMH_00178 1.2e-54 yabA L Involved in initiation control of chromosome replication
EONCEDMH_00179 3.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EONCEDMH_00180 8.7e-26 amt P Ammonium Transporter
EONCEDMH_00181 3.5e-104 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
EONCEDMH_00182 4.9e-39 S HD domain
EONCEDMH_00183 3.4e-40 S HD domain
EONCEDMH_00184 6.4e-140 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
EONCEDMH_00185 2e-75 S Bacterial inner membrane protein
EONCEDMH_00186 5.2e-113 3.4.17.14, 3.5.1.28 NU amidase activity
EONCEDMH_00187 3.5e-294 nptA P COG1283 Na phosphate symporter
EONCEDMH_00188 1e-215 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
EONCEDMH_00189 1.3e-200 S membrane
EONCEDMH_00190 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
EONCEDMH_00191 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
EONCEDMH_00192 1.7e-38 ynzC S UPF0291 protein
EONCEDMH_00193 7.4e-253 cycA E permease
EONCEDMH_00194 2.2e-10 uvrX 2.7.7.7 L impB/mucB/samB family
EONCEDMH_00195 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
EONCEDMH_00196 7.8e-140 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EONCEDMH_00201 3.7e-157 V AAA domain, putative AbiEii toxin, Type IV TA system
EONCEDMH_00202 5.8e-55 V ABC-2 type transporter
EONCEDMH_00203 1.2e-95
EONCEDMH_00205 9e-167 fhuR K transcriptional regulator (lysR family)
EONCEDMH_00206 1.4e-75 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EONCEDMH_00207 1.2e-160 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EONCEDMH_00208 4.8e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EONCEDMH_00209 4.7e-222 pyrP F uracil Permease
EONCEDMH_00210 5e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
EONCEDMH_00211 9.3e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
EONCEDMH_00212 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
EONCEDMH_00213 4.7e-129 2.1.1.223 S Putative SAM-dependent methyltransferase
EONCEDMH_00214 4.4e-180 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EONCEDMH_00215 4.4e-121 macB V ABC transporter, ATP-binding protein
EONCEDMH_00216 2.5e-209 V permease protein
EONCEDMH_00217 2.8e-77 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EONCEDMH_00218 2.1e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EONCEDMH_00220 2.5e-273 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
EONCEDMH_00221 4.6e-29 K DNA-binding transcription factor activity
EONCEDMH_00222 0.0 mdlB V abc transporter atp-binding protein
EONCEDMH_00223 0.0 lmrA V abc transporter atp-binding protein
EONCEDMH_00224 6.6e-198 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EONCEDMH_00225 3.4e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EONCEDMH_00226 1.8e-197 yceA S Belongs to the UPF0176 family
EONCEDMH_00227 1.6e-28 XK27_00085 K Transcriptional
EONCEDMH_00228 1.2e-24
EONCEDMH_00229 4.2e-141 deoD_1 2.4.2.3 F Phosphorylase superfamily
EONCEDMH_00230 3.9e-114 S VIT family
EONCEDMH_00231 2.2e-128 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EONCEDMH_00232 3.5e-216 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
EONCEDMH_00233 3.7e-199 ald 1.4.1.1 C Belongs to the AlaDH PNT family
EONCEDMH_00235 2.3e-121 E Alpha beta hydrolase
EONCEDMH_00236 2.6e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EONCEDMH_00237 3.8e-99 GBS0088 J protein conserved in bacteria
EONCEDMH_00238 4.6e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
EONCEDMH_00239 1.8e-170 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
EONCEDMH_00240 2.4e-165 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
EONCEDMH_00241 2.6e-183 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
EONCEDMH_00242 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
EONCEDMH_00243 2.9e-257 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EONCEDMH_00244 5.9e-97 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
EONCEDMH_00245 7.1e-24
EONCEDMH_00246 2.2e-117 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EONCEDMH_00247 0.0 U protein secretion
EONCEDMH_00248 8.3e-190 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
EONCEDMH_00249 1.3e-243 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
EONCEDMH_00250 6.8e-10
EONCEDMH_00251 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EONCEDMH_00252 2.9e-160 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EONCEDMH_00253 1.2e-199 S Protein of unknown function (DUF3114)
EONCEDMH_00254 4.1e-29 pspC KT PspC domain protein
EONCEDMH_00255 5.2e-119 yqfA K protein, Hemolysin III
EONCEDMH_00256 3.3e-77 K hmm pf08876
EONCEDMH_00257 7.7e-225 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
EONCEDMH_00258 9.3e-209 mvaS 2.3.3.10 I synthase
EONCEDMH_00259 2.7e-165 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EONCEDMH_00260 1.9e-89 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EONCEDMH_00261 9.7e-22
EONCEDMH_00262 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EONCEDMH_00263 3.9e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
EONCEDMH_00264 5.4e-248 mmuP E amino acid
EONCEDMH_00265 1.1e-167 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
EONCEDMH_00266 2.2e-30 S Domain of unknown function (DUF1912)
EONCEDMH_00267 4e-12 L Helix-hairpin-helix DNA-binding motif class 1
EONCEDMH_00268 5.6e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EONCEDMH_00269 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EONCEDMH_00271 1.3e-08
EONCEDMH_00272 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EONCEDMH_00273 9.1e-200 ilvE 2.6.1.42 E Aminotransferase
EONCEDMH_00274 4.1e-15 S Protein of unknown function (DUF2969)
EONCEDMH_00277 2.5e-204 rpsA 1.17.7.4 J ribosomal protein S1
EONCEDMH_00280 4.6e-106 S Domain of Unknown Function with PDB structure (DUF3862)
EONCEDMH_00281 8.7e-114 M Pfam SNARE associated Golgi protein
EONCEDMH_00282 9.5e-228 murN 2.3.2.16 V FemAB family
EONCEDMH_00283 7.5e-172 S oxidoreductase
EONCEDMH_00284 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
EONCEDMH_00285 2.2e-84 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
EONCEDMH_00286 0.0 clpE O Belongs to the ClpA ClpB family
EONCEDMH_00287 1.3e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EONCEDMH_00288 1e-34 ykuJ S protein conserved in bacteria
EONCEDMH_00289 5.8e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
EONCEDMH_00290 1.4e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
EONCEDMH_00291 2.7e-77 feoA P FeoA domain protein
EONCEDMH_00292 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
EONCEDMH_00293 6.6e-08
EONCEDMH_00294 2.3e-147 I Alpha/beta hydrolase family
EONCEDMH_00295 4.8e-154 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EONCEDMH_00296 5.2e-145 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EONCEDMH_00297 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
EONCEDMH_00298 1.3e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EONCEDMH_00299 3.3e-08 licT K antiterminator
EONCEDMH_00300 2.1e-109 licT K antiterminator
EONCEDMH_00301 3e-87 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EONCEDMH_00302 4.4e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
EONCEDMH_00303 3.4e-166 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EONCEDMH_00304 1.5e-141 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EONCEDMH_00305 1.9e-93 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EONCEDMH_00306 7.7e-222 mdtG EGP Major facilitator Superfamily
EONCEDMH_00307 2e-33 secG U Preprotein translocase subunit SecG
EONCEDMH_00308 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
EONCEDMH_00309 6.6e-81 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
EONCEDMH_00310 4.8e-276 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EONCEDMH_00311 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
EONCEDMH_00312 7.9e-194 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
EONCEDMH_00313 1.2e-180 ccpA K Catabolite control protein A
EONCEDMH_00314 1.9e-192 yyaQ S YjbR
EONCEDMH_00315 5.3e-193 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
EONCEDMH_00316 4.5e-74 yueI S Protein of unknown function (DUF1694)
EONCEDMH_00317 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EONCEDMH_00318 4.6e-25 WQ51_00785
EONCEDMH_00319 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
EONCEDMH_00320 1.1e-214 ywbD 2.1.1.191 J Methyltransferase
EONCEDMH_00321 4.1e-116 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
EONCEDMH_00322 5.9e-152 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EONCEDMH_00323 2.8e-199 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EONCEDMH_00324 6.4e-218 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EONCEDMH_00325 7e-206 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
EONCEDMH_00326 4.2e-53 yheA S Belongs to the UPF0342 family
EONCEDMH_00327 1.4e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
EONCEDMH_00328 2.1e-233 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
EONCEDMH_00329 4.7e-77 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EONCEDMH_00330 1.4e-153 pheA 4.2.1.51 E Prephenate dehydratase
EONCEDMH_00331 3.1e-238 msrR K Transcriptional regulator
EONCEDMH_00332 1.2e-153 ydiA P C4-dicarboxylate transporter malic acid transport
EONCEDMH_00333 4.2e-200 I acyl-CoA dehydrogenase
EONCEDMH_00334 2e-97 mip S hydroperoxide reductase activity
EONCEDMH_00335 1.6e-252 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EONCEDMH_00336 1.9e-77 P Mediates zinc uptake. May also transport other divalent cations
EONCEDMH_00337 2.4e-51 zupT P Mediates zinc uptake. May also transport other divalent cations
EONCEDMH_00338 1.6e-61 smtB K Transcriptional regulator
EONCEDMH_00339 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
EONCEDMH_00340 4.3e-22
EONCEDMH_00341 2e-217 EGP Transmembrane secretion effector
EONCEDMH_00342 1e-257 yheS_2 S ATPase components of ABC transporters with duplicated ATPase domains
EONCEDMH_00343 1.1e-49
EONCEDMH_00344 7.3e-59
EONCEDMH_00345 5.9e-55
EONCEDMH_00346 1.5e-36 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EONCEDMH_00347 9.1e-77 aacA7 2.3.1.82 K Acetyltransferase (GNAT) family
EONCEDMH_00348 8.8e-81 3.4.13.21, 3.4.15.6 PQ Peptidase family S51
EONCEDMH_00349 8.8e-113 K Bacterial regulatory proteins, tetR family
EONCEDMH_00350 1.4e-112 S ABC-type transport system involved in multi-copper enzyme maturation, permease component
EONCEDMH_00351 7.9e-129 bcrA V abc transporter atp-binding protein
EONCEDMH_00352 7.7e-297 V ABC transporter transmembrane region
EONCEDMH_00353 1.7e-12
EONCEDMH_00354 1.4e-131 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EONCEDMH_00355 1.7e-131 S Domain of unknown function (DUF4336)
EONCEDMH_00356 6.5e-202 yeaN P transporter
EONCEDMH_00357 5.1e-148 yitS S EDD domain protein, DegV family
EONCEDMH_00358 5.8e-95 XK27_08140 K Bacterial regulatory proteins, tetR family
EONCEDMH_00359 1.5e-95 ypgQ F HD superfamily hydrolase
EONCEDMH_00360 7.5e-128 S CAAX amino terminal protease family
EONCEDMH_00361 1.5e-107 cutC P Participates in the control of copper homeostasis
EONCEDMH_00363 4.1e-21 S Domain of unknown function (DUF4767)
EONCEDMH_00364 3.9e-283 norB P Major facilitator superfamily
EONCEDMH_00365 6.3e-91 tetR K transcriptional regulator
EONCEDMH_00366 2.1e-146 S Domain of unknown function (DUF4300)
EONCEDMH_00367 1.5e-114 V CAAX protease self-immunity
EONCEDMH_00368 1.4e-158 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EONCEDMH_00369 8.3e-134 fecE 3.6.3.34 HP ABC transporter
EONCEDMH_00370 1.1e-173 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
EONCEDMH_00371 7.1e-124 ybbA S Putative esterase
EONCEDMH_00372 3.3e-158 yegS 2.7.1.107 I Diacylglycerol kinase
EONCEDMH_00373 4.7e-172 S Domain of unknown function (DUF389)
EONCEDMH_00375 2.3e-29 S Membrane
EONCEDMH_00376 4e-96
EONCEDMH_00377 1.5e-22 S Small integral membrane protein
EONCEDMH_00378 7.7e-68 S Asp23 family, cell envelope-related function
EONCEDMH_00379 3.3e-08 K CsbD-like
EONCEDMH_00380 3.3e-08 K CsbD-like
EONCEDMH_00381 1e-174 pdhD 1.8.1.4 C Dehydrogenase
EONCEDMH_00382 2.8e-167 acoA C Acetoin dehydrogenase E1 component subunit alpha
EONCEDMH_00383 3.9e-174 acoB C dehydrogenase E1 component
EONCEDMH_00384 1.2e-142 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EONCEDMH_00385 8.1e-84 Q Methyltransferase domain
EONCEDMH_00386 3.2e-56 K TetR family transcriptional regulator
EONCEDMH_00387 5.4e-47
EONCEDMH_00388 2.8e-129 V CAAX protease self-immunity
EONCEDMH_00389 8.9e-11
EONCEDMH_00390 2.6e-20 M Bacterial lipoprotein
EONCEDMH_00391 6.4e-61 S Protein of unknown function (DUF1722)
EONCEDMH_00392 4.8e-63 yqeB S Pyrimidine dimer DNA glycosylase
EONCEDMH_00394 3.2e-51
EONCEDMH_00395 4e-94 S CAAX protease self-immunity
EONCEDMH_00396 1.6e-117 estA E GDSL-like Lipase/Acylhydrolase
EONCEDMH_00397 9.6e-104
EONCEDMH_00398 6e-286 sulP P Sulfate permease and related transporters (MFS superfamily)
EONCEDMH_00399 1.5e-263 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
EONCEDMH_00400 7.3e-252 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
EONCEDMH_00401 9.3e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EONCEDMH_00402 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EONCEDMH_00403 2.2e-169 S CRISPR-associated protein Csn2 subfamily St
EONCEDMH_00404 9.9e-149 ycgQ S TIGR03943 family
EONCEDMH_00405 4.2e-156 XK27_03015 S permease
EONCEDMH_00407 0.0 yhgF K Transcriptional accessory protein
EONCEDMH_00408 2.2e-41 pspC KT PspC domain
EONCEDMH_00409 8.3e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EONCEDMH_00410 6.4e-145 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EONCEDMH_00411 3.1e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EONCEDMH_00412 2.3e-67 ytxH S General stress protein
EONCEDMH_00414 1.5e-177 yegQ O Peptidase U32
EONCEDMH_00415 1.7e-251 yegQ O Peptidase U32
EONCEDMH_00416 1.1e-87 bioY S biotin synthase
EONCEDMH_00418 1.1e-33 XK27_12190 S protein conserved in bacteria
EONCEDMH_00419 4.3e-234 mntH P H( )-stimulated, divalent metal cation uptake system
EONCEDMH_00420 2.8e-11
EONCEDMH_00421 1.6e-14
EONCEDMH_00422 7.1e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
EONCEDMH_00423 6.3e-137 M LysM domain
EONCEDMH_00424 8.4e-23
EONCEDMH_00425 5.2e-175 S hydrolase
EONCEDMH_00427 3.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
EONCEDMH_00428 2.5e-80 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EONCEDMH_00429 9.4e-140 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
EONCEDMH_00430 3e-26 P Hemerythrin HHE cation binding domain protein
EONCEDMH_00431 4.3e-155 5.2.1.8 G hydrolase
EONCEDMH_00432 5.2e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EONCEDMH_00433 3.8e-194 MA20_36090 S Protein of unknown function (DUF2974)
EONCEDMH_00434 2.9e-134 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
EONCEDMH_00435 1e-43 S Nucleotide pyrophosphohydrolase
EONCEDMH_00436 1.2e-188 L Uncharacterized conserved protein (DUF2075)
EONCEDMH_00437 5.4e-132 S double-stranded DNA endodeoxyribonuclease activity
EONCEDMH_00438 0.0 2.4.1.21 GT5 M Right handed beta helix region
EONCEDMH_00439 2.2e-166 spd F DNA RNA non-specific endonuclease
EONCEDMH_00440 7.7e-92 lemA S LemA family
EONCEDMH_00441 1.3e-133 htpX O Belongs to the peptidase M48B family
EONCEDMH_00442 2e-112 sirR K iron dependent repressor
EONCEDMH_00443 1.8e-167 sitA P Belongs to the bacterial solute-binding protein 9 family
EONCEDMH_00444 2.3e-132 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
EONCEDMH_00445 1.6e-126 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
EONCEDMH_00446 6.1e-74 S Psort location CytoplasmicMembrane, score
EONCEDMH_00447 6.2e-64 S Domain of unknown function (DUF4430)
EONCEDMH_00448 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EONCEDMH_00449 2.2e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
EONCEDMH_00450 6.1e-111 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
EONCEDMH_00451 1.4e-163 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
EONCEDMH_00452 3.1e-100 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
EONCEDMH_00453 9e-79 dps P Belongs to the Dps family
EONCEDMH_00454 3.4e-79 perR P Belongs to the Fur family
EONCEDMH_00455 4.2e-27 yqgQ S protein conserved in bacteria
EONCEDMH_00456 1.1e-175 glk 2.7.1.2 G Glucokinase
EONCEDMH_00457 0.0 typA T GTP-binding protein TypA
EONCEDMH_00459 9e-248 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EONCEDMH_00460 1.2e-197 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EONCEDMH_00461 7.4e-134 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
EONCEDMH_00462 1e-222 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EONCEDMH_00463 2.8e-233 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EONCEDMH_00464 1.9e-121 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EONCEDMH_00465 3.4e-90 sepF D cell septum assembly
EONCEDMH_00466 1.7e-30 yggT D integral membrane protein
EONCEDMH_00467 8.6e-137 ylmH S conserved protein, contains S4-like domain
EONCEDMH_00468 5.5e-137 divIVA D Cell division initiation protein
EONCEDMH_00469 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EONCEDMH_00470 3.8e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EONCEDMH_00471 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EONCEDMH_00472 6.5e-34 nrdH O Glutaredoxin
EONCEDMH_00473 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EONCEDMH_00474 2.4e-209 citZ 2.3.3.1 C Belongs to the citrate synthase family
EONCEDMH_00475 7.7e-219 icd 1.1.1.42 C Isocitrate dehydrogenase
EONCEDMH_00476 3e-38 ptsH G phosphocarrier protein Hpr
EONCEDMH_00477 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EONCEDMH_00478 6.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
EONCEDMH_00479 5.1e-161 XK27_05670 S Putative esterase
EONCEDMH_00480 2.7e-153 XK27_05675 S Esterase
EONCEDMH_00481 5.4e-225 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
EONCEDMH_00482 8.7e-177 yfmL 3.6.4.13 L DEAD DEAH box helicase
EONCEDMH_00483 6.8e-113 udk 2.7.1.48 F Cytidine monophosphokinase
EONCEDMH_00484 0.0 uup S abc transporter atp-binding protein
EONCEDMH_00485 1.6e-39 MA20_06245 S yiaA/B two helix domain
EONCEDMH_00486 1.7e-131 pip 1.11.1.10 S Alpha beta hydrolase
EONCEDMH_00487 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EONCEDMH_00488 6.2e-148 cobQ S glutamine amidotransferase
EONCEDMH_00489 5.4e-253 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
EONCEDMH_00490 1.1e-147 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EONCEDMH_00491 1.1e-162 ybbR S Protein conserved in bacteria
EONCEDMH_00492 1.3e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EONCEDMH_00493 1.3e-64 gtrA S GtrA-like protein
EONCEDMH_00494 1.1e-119 trmK 2.1.1.217 S SAM-dependent methyltransferase
EONCEDMH_00495 1.7e-142 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EONCEDMH_00496 1.1e-142 zupT P Mediates zinc uptake. May also transport other divalent cations
EONCEDMH_00497 1.9e-200 yurR 1.4.5.1 E oxidoreductase
EONCEDMH_00498 1.9e-258 S phospholipase Carboxylesterase
EONCEDMH_00499 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EONCEDMH_00500 1.9e-112 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
EONCEDMH_00501 1.3e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EONCEDMH_00503 5.4e-29 KT response to antibiotic
EONCEDMH_00504 2.5e-214 hemN H Involved in the biosynthesis of porphyrin-containing compound
EONCEDMH_00505 1.1e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
EONCEDMH_00506 1.2e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
EONCEDMH_00507 3.7e-114 ylfI S tigr01906
EONCEDMH_00508 8.7e-136 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
EONCEDMH_00509 1.6e-147 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
EONCEDMH_00510 2.9e-58 XK27_08085
EONCEDMH_00511 1.9e-192 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EONCEDMH_00512 9e-181 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EONCEDMH_00513 8e-117 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
EONCEDMH_00514 5.4e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EONCEDMH_00515 3.9e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
EONCEDMH_00516 2.6e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EONCEDMH_00517 2.2e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EONCEDMH_00518 2.1e-137 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EONCEDMH_00519 1.1e-58 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EONCEDMH_00520 4.1e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
EONCEDMH_00522 7.6e-94 XK27_05505 S Psort location CytoplasmicMembrane, score
EONCEDMH_00523 1.8e-144 P molecular chaperone
EONCEDMH_00524 1.8e-96 S Carbohydrate-binding domain-containing protein Cthe_2159
EONCEDMH_00525 5.2e-179 XK27_08075 M glycosyl transferase family 2
EONCEDMH_00526 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
EONCEDMH_00527 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
EONCEDMH_00528 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
EONCEDMH_00529 3.2e-227 rodA D Belongs to the SEDS family
EONCEDMH_00530 1.1e-245 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EONCEDMH_00531 1.5e-112 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
EONCEDMH_00532 2.7e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
EONCEDMH_00533 3.7e-137 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
EONCEDMH_00534 4.1e-19 Q Methyltransferase domain
EONCEDMH_00535 1.5e-65 GnaT 2.5.1.16 K acetyltransferase
EONCEDMH_00536 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
EONCEDMH_00537 1.7e-93 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EONCEDMH_00538 1.8e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EONCEDMH_00539 1.3e-125 dnaD
EONCEDMH_00540 1.3e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EONCEDMH_00542 6.2e-233 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EONCEDMH_00543 4.6e-29 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EONCEDMH_00544 5.2e-156 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
EONCEDMH_00545 1.5e-147 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
EONCEDMH_00546 2.8e-73 argR K Regulates arginine biosynthesis genes
EONCEDMH_00547 5.6e-300 recN L May be involved in recombinational repair of damaged DNA
EONCEDMH_00548 6.9e-145 DegV S DegV family
EONCEDMH_00549 1.5e-155 ypmR E COG2755 Lysophospholipase L1 and related esterases
EONCEDMH_00550 1.3e-94 ypmS S Protein conserved in bacteria
EONCEDMH_00551 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EONCEDMH_00553 2.3e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
EONCEDMH_00554 3.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EONCEDMH_00555 2e-52 hxlR K HxlR-like helix-turn-helix
EONCEDMH_00556 2e-70 S SnoaL-like polyketide cyclase
EONCEDMH_00557 8.1e-54 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EONCEDMH_00558 2.4e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EONCEDMH_00559 6.2e-188 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
EONCEDMH_00560 4.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EONCEDMH_00561 2.4e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EONCEDMH_00562 0.0 dnaE 2.7.7.7 L DNA polymerase
EONCEDMH_00563 1e-187 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
EONCEDMH_00564 2.7e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
EONCEDMH_00565 0.0 htaA 3.4.21.72 Q the current gene model (or a revised gene model) may contain a frame shift
EONCEDMH_00566 1.7e-18 S Domain of unknown function (DUF4649)
EONCEDMH_00567 2.4e-176 XK27_08835 S ABC transporter substrate binding protein
EONCEDMH_00568 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
EONCEDMH_00569 8.9e-136 XK27_08845 S abc transporter atp-binding protein
EONCEDMH_00570 1.5e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EONCEDMH_00571 9.5e-149 estA CE1 S Esterase
EONCEDMH_00572 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
EONCEDMH_00573 3.4e-19 XK27_08880
EONCEDMH_00574 1e-75 fld C Flavodoxin
EONCEDMH_00575 3.2e-281 clcA P Chloride transporter, ClC family
EONCEDMH_00576 1.2e-37 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
EONCEDMH_00577 2.3e-213 XK27_05110 P Chloride transporter ClC family
EONCEDMH_00578 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EONCEDMH_00581 3.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
EONCEDMH_00582 1.5e-158 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EONCEDMH_00583 3.7e-85 ytsP 1.8.4.14 T GAF domain-containing protein
EONCEDMH_00584 1.7e-301 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EONCEDMH_00585 1.1e-170 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EONCEDMH_00586 1e-210 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EONCEDMH_00587 2.1e-276 5.1.3.2 GM Psort location CytoplasmicMembrane, score
EONCEDMH_00588 2.7e-147
EONCEDMH_00589 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
EONCEDMH_00590 1.1e-272 pelF GT4 M Domain of unknown function (DUF3492)
EONCEDMH_00591 4.4e-184 pelG M Putative exopolysaccharide Exporter (EPS-E)
EONCEDMH_00592 1e-222 cotH M CotH kinase protein
EONCEDMH_00593 5.1e-96 P VTC domain
EONCEDMH_00594 2.7e-83 S membrane
EONCEDMH_00595 7e-134 G Domain of unknown function (DUF4832)
EONCEDMH_00596 2.5e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EONCEDMH_00598 2.1e-230 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EONCEDMH_00599 7.2e-26 epuA S DNA-directed RNA polymerase subunit beta
EONCEDMH_00600 1.9e-153 endA F DNA RNA non-specific endonuclease
EONCEDMH_00601 1.4e-106 tcyB_2 P ABC transporter (permease)
EONCEDMH_00602 1.9e-116 gltJ P ABC transporter (Permease
EONCEDMH_00604 1.3e-49 bta 1.8.1.8 CO cell redox homeostasis
EONCEDMH_00605 8.2e-59 L thioesterase
EONCEDMH_00606 3.3e-141 S Macro domain protein
EONCEDMH_00607 5.3e-50 trxA O Belongs to the thioredoxin family
EONCEDMH_00608 3.7e-70 yccU S CoA-binding protein
EONCEDMH_00609 6.8e-142 tatD L Hydrolase, tatd
EONCEDMH_00610 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EONCEDMH_00611 2.4e-153 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EONCEDMH_00613 9.2e-161 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EONCEDMH_00614 7.8e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
EONCEDMH_00615 4e-113 thiN 2.7.6.2 H thiamine pyrophosphokinase
EONCEDMH_00616 7.9e-169 rmuC S RmuC domain protein
EONCEDMH_00617 3.1e-178 cbf S 3'-5' exoribonuclease yhaM
EONCEDMH_00618 4e-142 purR 2.4.2.7 F operon repressor
EONCEDMH_00619 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EONCEDMH_00620 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EONCEDMH_00621 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EONCEDMH_00622 7.1e-181 gap 1.2.1.12 C Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
EONCEDMH_00623 3.4e-121
EONCEDMH_00624 5.8e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
EONCEDMH_00625 3e-87 S Fusaric acid resistance protein-like
EONCEDMH_00626 2.5e-62 glnR K Transcriptional regulator
EONCEDMH_00627 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
EONCEDMH_00628 1.6e-114 pscB M CHAP domain protein
EONCEDMH_00629 1.4e-223 L Transposase
EONCEDMH_00630 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EONCEDMH_00631 1.5e-33 ykzG S Belongs to the UPF0356 family
EONCEDMH_00632 1.5e-118 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
EONCEDMH_00633 4.8e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
EONCEDMH_00634 1.3e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EONCEDMH_00635 2.8e-112 azlC E AzlC protein
EONCEDMH_00636 4.4e-47 azlD S branched-chain amino acid
EONCEDMH_00637 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EONCEDMH_00638 6.1e-106 lepB 3.4.21.89 U Belongs to the peptidase S26 family
EONCEDMH_00639 5.4e-153 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EONCEDMH_00640 9.3e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EONCEDMH_00641 6.7e-93 cvpA S toxin biosynthetic process
EONCEDMH_00642 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EONCEDMH_00643 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EONCEDMH_00645 3.7e-34
EONCEDMH_00647 4.9e-218 mutY L A G-specific adenine glycosylase
EONCEDMH_00648 7.2e-42 XK27_05745
EONCEDMH_00649 3e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
EONCEDMH_00650 2.5e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EONCEDMH_00651 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EONCEDMH_00653 8.5e-122 XK27_01040 S Protein of unknown function (DUF1129)
EONCEDMH_00654 4.2e-167 corA P COG0598 Mg2 and Co2 transporters
EONCEDMH_00655 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EONCEDMH_00659 2.1e-32 blpT
EONCEDMH_00660 5.1e-145 V 'abc transporter, ATP-binding protein
EONCEDMH_00662 2e-186 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
EONCEDMH_00663 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
EONCEDMH_00664 7.1e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EONCEDMH_00665 1.7e-61 yqhY S protein conserved in bacteria
EONCEDMH_00666 8.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EONCEDMH_00667 7.5e-180 scrR K Transcriptional regulator
EONCEDMH_00668 2.6e-285 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
EONCEDMH_00669 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
EONCEDMH_00670 6.5e-170 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
EONCEDMH_00671 1.9e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
EONCEDMH_00673 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EONCEDMH_00674 1.9e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EONCEDMH_00675 1.4e-195 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EONCEDMH_00676 3.4e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EONCEDMH_00677 2.5e-203 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EONCEDMH_00678 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EONCEDMH_00682 2.4e-30 yozG K Transcriptional regulator
EONCEDMH_00683 4.7e-280 V ABC transporter transmembrane region
EONCEDMH_00684 1.8e-156 K Helix-turn-helix XRE-family like proteins
EONCEDMH_00686 4.6e-177 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
EONCEDMH_00687 1.4e-259 XK27_03190 S hydrolases of the HAD superfamily
EONCEDMH_00688 1.6e-102 yebC M Membrane
EONCEDMH_00689 1.2e-310 KT response to antibiotic
EONCEDMH_00690 1.5e-74 XK27_02470 K LytTr DNA-binding domain
EONCEDMH_00691 4.8e-120 liaI S membrane
EONCEDMH_00692 6.2e-76 mccF V LD-carboxypeptidase
EONCEDMH_00693 4e-43 S Sugar efflux transporter for intercellular exchange
EONCEDMH_00694 4.7e-196 mccF V the current gene model (or a revised gene model) may contain a frame shift
EONCEDMH_00695 1.7e-298 O MreB/Mbl protein
EONCEDMH_00697 1.3e-145 V Psort location CytoplasmicMembrane, score
EONCEDMH_00700 6.8e-14
EONCEDMH_00701 7.2e-226 dcuS 2.7.13.3 T protein histidine kinase activity
EONCEDMH_00702 2.9e-233 2.7.13.3 T protein histidine kinase activity
EONCEDMH_00703 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EONCEDMH_00704 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
EONCEDMH_00705 4e-125 S Protein of unknown function (DUF554)
EONCEDMH_00706 4e-133 ecsA_2 V abc transporter atp-binding protein
EONCEDMH_00707 1.4e-284 XK27_00765
EONCEDMH_00708 6.3e-140 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EONCEDMH_00709 3.9e-221 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EONCEDMH_00710 8.9e-55 yhaI J Membrane
EONCEDMH_00711 1.3e-61 yhaI J Protein of unknown function (DUF805)
EONCEDMH_00712 1.4e-42 yhaI J Protein of unknown function (DUF805)
EONCEDMH_00715 5.2e-63
EONCEDMH_00716 2.2e-08
EONCEDMH_00717 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EONCEDMH_00718 2.4e-45 ftsL D cell division protein FtsL
EONCEDMH_00719 0.0 ftsI 3.4.16.4 M penicillin-binding protein
EONCEDMH_00720 7e-184 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EONCEDMH_00721 3.6e-220 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EONCEDMH_00722 6.6e-151 V ATPases associated with a variety of cellular activities
EONCEDMH_00723 3.9e-123
EONCEDMH_00724 2.3e-128 KT COG3279 Response regulator of the LytR AlgR family
EONCEDMH_00725 3e-213 T GHKL domain
EONCEDMH_00727 3.7e-249 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
EONCEDMH_00728 2e-60 yutD J protein conserved in bacteria
EONCEDMH_00729 3.9e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EONCEDMH_00730 1.2e-91 XK27_09885 V Glycopeptide antibiotics resistance protein
EONCEDMH_00733 0.0 mdlA V abc transporter atp-binding protein
EONCEDMH_00734 0.0 mdlB V abc transporter atp-binding protein
EONCEDMH_00741 9.2e-44 spiA K sequence-specific DNA binding
EONCEDMH_00745 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
EONCEDMH_00746 5.6e-150 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
EONCEDMH_00747 1.2e-93 V CAAX protease self-immunity
EONCEDMH_00748 4.7e-137 cppA E CppA N-terminal
EONCEDMH_00749 3.1e-170 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
EONCEDMH_00751 1.1e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EONCEDMH_00752 1.9e-141 cah 4.2.1.1 P carbonic anhydrase
EONCEDMH_00753 0.0 pflB 2.3.1.54 C formate acetyltransferase'
EONCEDMH_00754 7.3e-203 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EONCEDMH_00755 8e-35
EONCEDMH_00756 9.7e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
EONCEDMH_00757 1.4e-162 yxeN P ABC transporter (Permease
EONCEDMH_00758 5.2e-128 tcyN 3.6.3.21 E abc transporter atp-binding protein
EONCEDMH_00759 5e-10 S Protein of unknown function (DUF4059)
EONCEDMH_00760 2.1e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EONCEDMH_00761 9.6e-92 rsmD 2.1.1.171 L Methyltransferase
EONCEDMH_00762 1.9e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EONCEDMH_00763 3.2e-187 ylbL T Belongs to the peptidase S16 family
EONCEDMH_00764 1e-181 yhcC S radical SAM protein
EONCEDMH_00765 1.9e-95 ytqB J (SAM)-dependent
EONCEDMH_00767 0.0 yjcE P NhaP-type Na H and K H antiporters
EONCEDMH_00769 1.8e-24
EONCEDMH_00771 1.2e-140 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
EONCEDMH_00772 3.2e-237 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
EONCEDMH_00773 1.4e-08 MU outer membrane autotransporter barrel domain protein
EONCEDMH_00774 1.5e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EONCEDMH_00776 9e-75 XK27_03180 T universal stress protein
EONCEDMH_00777 1.7e-237 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
EONCEDMH_00778 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EONCEDMH_00779 4.4e-100 pncA Q isochorismatase
EONCEDMH_00780 2.2e-292 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EONCEDMH_00781 5.7e-217 M lipopolysaccharide 3-alpha-galactosyltransferase activity
EONCEDMH_00782 5.7e-158 H COG0463 Glycosyltransferases involved in cell wall biogenesis
EONCEDMH_00783 2.6e-191 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
EONCEDMH_00784 3.6e-234 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
EONCEDMH_00785 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EONCEDMH_00786 1.3e-268 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EONCEDMH_00787 1.9e-272 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EONCEDMH_00788 9.3e-65
EONCEDMH_00789 3.7e-152 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
EONCEDMH_00790 2.3e-98 yqeG S hydrolase of the HAD superfamily
EONCEDMH_00791 1.6e-213 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
EONCEDMH_00792 7.7e-49 yhbY J RNA-binding protein
EONCEDMH_00793 3.5e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EONCEDMH_00794 8.3e-105 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
EONCEDMH_00795 2e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EONCEDMH_00796 2.9e-139 yqeM Q Methyltransferase domain protein
EONCEDMH_00797 1.2e-194 ylbM S Belongs to the UPF0348 family
EONCEDMH_00798 7.6e-39 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
EONCEDMH_00799 3.9e-43 yoeB S Addiction module toxin, Txe YoeB family
EONCEDMH_00800 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
EONCEDMH_00803 4.1e-07
EONCEDMH_00804 1e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
EONCEDMH_00805 3.7e-131 ecsA V abc transporter atp-binding protein
EONCEDMH_00806 1e-174 ecsB U Bacterial ABC transporter protein EcsB
EONCEDMH_00807 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
EONCEDMH_00808 2.6e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EONCEDMH_00810 2.7e-222 L the current gene model (or a revised gene model) may contain a frame shift
EONCEDMH_00811 3.9e-212 ytfP S Flavoprotein
EONCEDMH_00812 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
EONCEDMH_00813 9.6e-64 XK27_02560 S cog cog2151
EONCEDMH_00814 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
EONCEDMH_00815 4.9e-105 dnaQ 2.7.7.7 L DNA polymerase III
EONCEDMH_00816 8.9e-125 K transcriptional regulator, MerR family
EONCEDMH_00817 0.0 V ABC transporter (Permease
EONCEDMH_00818 9.5e-124 V abc transporter atp-binding protein
EONCEDMH_00820 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EONCEDMH_00821 1.1e-47
EONCEDMH_00824 0.0
EONCEDMH_00825 0.0 bcsA 2.4.1.12 GT2 M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
EONCEDMH_00826 1.1e-150 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
EONCEDMH_00827 4.4e-162 T Diguanylate cyclase
EONCEDMH_00828 2.2e-35 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
EONCEDMH_00829 2.2e-60 fruR K transcriptional
EONCEDMH_00830 6.7e-26 L Transposase
EONCEDMH_00831 3.7e-45
EONCEDMH_00832 0.0 ctpE P E1-E2 ATPase
EONCEDMH_00833 2e-58
EONCEDMH_00834 2.2e-39 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
EONCEDMH_00835 3.1e-256 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EONCEDMH_00836 8e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
EONCEDMH_00837 5.6e-178 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EONCEDMH_00838 1.4e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
EONCEDMH_00839 1e-99 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
EONCEDMH_00840 1.4e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
EONCEDMH_00841 2.5e-141 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
EONCEDMH_00843 5e-162 EGP Major facilitator Superfamily
EONCEDMH_00844 6.1e-73 copY K negative regulation of transcription, DNA-templated
EONCEDMH_00845 0.0 copA 3.6.3.54 P P-type ATPase
EONCEDMH_00846 2.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
EONCEDMH_00847 2.5e-34 K Transcriptional regulator C-terminal region
EONCEDMH_00848 2.9e-83 V ABC transporter
EONCEDMH_00849 1.5e-56
EONCEDMH_00850 6.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
EONCEDMH_00851 2.5e-113 papP P ABC transporter (Permease
EONCEDMH_00852 3e-106 P ABC transporter (Permease
EONCEDMH_00853 7.6e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
EONCEDMH_00854 9.7e-155 cjaA ET ABC transporter substrate-binding protein
EONCEDMH_00858 9.5e-253 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EONCEDMH_00859 2.1e-117 ywaF S Integral membrane protein (intg_mem_TP0381)
EONCEDMH_00860 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EONCEDMH_00861 3.7e-197 yjbB G Permeases of the major facilitator superfamily
EONCEDMH_00862 1.5e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
EONCEDMH_00863 2e-95 thiT S Thiamine transporter
EONCEDMH_00864 9.6e-62 yjqA S Bacterial PH domain
EONCEDMH_00865 4e-151 corA P CorA-like protein
EONCEDMH_00866 2.2e-245 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EONCEDMH_00867 1e-41 yazA L endonuclease containing a URI domain
EONCEDMH_00868 4.6e-140 yabB 2.1.1.223 L Methyltransferase
EONCEDMH_00869 7.4e-148 nodB3 G Polysaccharide deacetylase
EONCEDMH_00870 2.9e-142 plsC 2.3.1.51 I Acyltransferase
EONCEDMH_00871 3.7e-88 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
EONCEDMH_00872 0.0 comEC S Competence protein ComEC
EONCEDMH_00873 2.3e-229 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EONCEDMH_00874 3.5e-97 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
EONCEDMH_00875 3e-232 ytoI K transcriptional regulator containing CBS domains
EONCEDMH_00876 1.1e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
EONCEDMH_00877 8.4e-160 rbn E Belongs to the UPF0761 family
EONCEDMH_00878 2.8e-85 ccl S cog cog4708
EONCEDMH_00879 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EONCEDMH_00880 3.1e-184 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EONCEDMH_00882 4.5e-172 yfjR K regulation of single-species biofilm formation
EONCEDMH_00884 3.9e-68 S QueT transporter
EONCEDMH_00885 7.7e-157 xth 3.1.11.2 L exodeoxyribonuclease III
EONCEDMH_00887 9.5e-64 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EONCEDMH_00888 3.7e-17 yjdB S Domain of unknown function (DUF4767)
EONCEDMH_00889 4.3e-166 tehB 2.1.1.265 PQ tellurite resistance protein tehb
EONCEDMH_00890 4.2e-165 O protein import
EONCEDMH_00891 2.2e-123 agrA KT phosphorelay signal transduction system
EONCEDMH_00892 1.5e-210 2.7.13.3 T protein histidine kinase activity
EONCEDMH_00894 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
EONCEDMH_00895 1.5e-36 ylqC L Belongs to the UPF0109 family
EONCEDMH_00896 7.7e-233 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
EONCEDMH_00897 0.0 ydaO E amino acid
EONCEDMH_00898 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
EONCEDMH_00899 1.3e-145 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EONCEDMH_00900 5.3e-294 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
EONCEDMH_00901 2.5e-59 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EONCEDMH_00902 1.6e-77 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EONCEDMH_00903 5.8e-166 murB 1.3.1.98 M cell wall formation
EONCEDMH_00904 2.6e-211 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
EONCEDMH_00905 4.1e-139 potB P ABC-type spermidine putrescine transport system, permease component I
EONCEDMH_00906 2.3e-131 potC P ABC-type spermidine putrescine transport system, permease component II
EONCEDMH_00907 8.3e-204 potD P spermidine putrescine ABC transporter
EONCEDMH_00908 1.9e-145 XK27_08050 O HflC and HflK could regulate a protease
EONCEDMH_00909 1.8e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
EONCEDMH_00910 1.9e-153 GK ROK family
EONCEDMH_00911 5.1e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EONCEDMH_00912 6.9e-101 wecD M Acetyltransferase (GNAT) domain
EONCEDMH_00913 4.5e-219 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EONCEDMH_00914 7e-73 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
EONCEDMH_00915 5.4e-59 arsC 1.20.4.1 P Belongs to the ArsC family
EONCEDMH_00917 5.9e-56 lrgA S Effector of murein hydrolase LrgA
EONCEDMH_00918 1.9e-116 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
EONCEDMH_00919 2.9e-105 3.1.3.18 S IA, variant 1
EONCEDMH_00920 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EONCEDMH_00921 3.2e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EONCEDMH_00922 2.9e-111 serB 3.1.3.3 E phosphoserine phosphatase
EONCEDMH_00923 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
EONCEDMH_00924 4.1e-161 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EONCEDMH_00925 3.2e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EONCEDMH_00926 1.6e-104 csn2 S CRISPR-associated protein (Cas_Csn2)
EONCEDMH_00927 1e-08 N PFAM Uncharacterised protein family UPF0150
EONCEDMH_00928 2e-150 EG Permeases of the drug metabolite transporter (DMT) superfamily
EONCEDMH_00930 1.3e-60 ycaO O OsmC-like protein
EONCEDMH_00931 1.9e-62 paaI Q protein possibly involved in aromatic compounds catabolism
EONCEDMH_00932 1.3e-09 O ADP-ribosylglycohydrolase
EONCEDMH_00933 1.1e-125 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EONCEDMH_00935 8.8e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EONCEDMH_00936 1.7e-17 XK27_00735
EONCEDMH_00937 1.1e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
EONCEDMH_00938 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
EONCEDMH_00939 1.4e-162 S CAAX amino terminal protease family protein
EONCEDMH_00941 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EONCEDMH_00942 1.8e-78 mutT 3.6.1.55 F Nudix family
EONCEDMH_00943 2.5e-136 ET ABC transporter
EONCEDMH_00944 1.2e-135 ET Belongs to the bacterial solute-binding protein 3 family
EONCEDMH_00945 4.1e-206 arcT 2.6.1.1 E Aminotransferase
EONCEDMH_00946 7.9e-135 gltS ET Belongs to the bacterial solute-binding protein 3 family
EONCEDMH_00947 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
EONCEDMH_00948 6.4e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EONCEDMH_00949 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EONCEDMH_00950 4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EONCEDMH_00951 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
EONCEDMH_00952 4.4e-169 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
EONCEDMH_00953 8.9e-240
EONCEDMH_00954 1.7e-159 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
EONCEDMH_00955 4.2e-124 ycbB S Glycosyl transferase family 2
EONCEDMH_00956 1.1e-45 XK27_09090 S Uncharacterized conserved protein (DUF2304)
EONCEDMH_00957 7.3e-215 amrA S polysaccharide biosynthetic process
EONCEDMH_00958 5.4e-128 2.7.8.12 M transferase activity, transferring glycosyl groups
EONCEDMH_00959 2.9e-141 S Predicted membrane protein (DUF2142)
EONCEDMH_00960 6.6e-215 rgpA GT4 M Domain of unknown function (DUF1972)
EONCEDMH_00961 1.1e-170 rgpB GT2 M Glycosyltransferase, group 2 family protein
EONCEDMH_00962 1.2e-141 rgpC GM Transport permease protein
EONCEDMH_00963 8.1e-224 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
EONCEDMH_00964 1.6e-183 rgpEc GT2 M Glycosyl transferase family 2
EONCEDMH_00965 0.0 rgpF M Rhamnan synthesis protein F
EONCEDMH_00966 2.6e-118 radC E Belongs to the UPF0758 family
EONCEDMH_00967 1e-130 puuD T peptidase C26
EONCEDMH_00968 1.9e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EONCEDMH_00969 8.2e-60 XK27_04120 S Putative amino acid metabolism
EONCEDMH_00970 1.4e-206 iscS 2.8.1.7 E Cysteine desulfurase
EONCEDMH_00971 8.7e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EONCEDMH_00972 2.4e-101 yjbK S Adenylate cyclase
EONCEDMH_00973 3e-119 yjbM 2.7.6.5 S Gtp pyrophosphokinase
EONCEDMH_00974 3.4e-152 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EONCEDMH_00975 1e-170 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
EONCEDMH_00976 2.2e-174 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
EONCEDMH_00977 0.0 amiA E ABC transporter, substrate-binding protein, family 5
EONCEDMH_00978 2.7e-311 amiA E ABC transporter, substrate-binding protein, family 5
EONCEDMH_00979 8.1e-274 amiC P ABC transporter (Permease
EONCEDMH_00980 2.9e-165 amiD P ABC transporter (Permease
EONCEDMH_00981 9.3e-203 oppD P Belongs to the ABC transporter superfamily
EONCEDMH_00982 3.1e-170 oppF P Belongs to the ABC transporter superfamily
EONCEDMH_00983 1.4e-128 V Psort location CytoplasmicMembrane, score
EONCEDMH_00984 1.8e-119 skfE V abc transporter atp-binding protein
EONCEDMH_00985 2.8e-61 yvoA_1 K Transcriptional
EONCEDMH_00986 2.2e-145 supH S overlaps another CDS with the same product name
EONCEDMH_00987 3.1e-142 XK27_02985 S overlaps another CDS with the same product name
EONCEDMH_00988 3.2e-195 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EONCEDMH_00989 8.8e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
EONCEDMH_00990 3.6e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
EONCEDMH_00991 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EONCEDMH_00992 9.9e-169 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EONCEDMH_00993 8.1e-241 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EONCEDMH_00994 3.8e-134 stp 3.1.3.16 T phosphatase
EONCEDMH_00995 2.6e-293 prkC 2.7.11.1 KLT serine threonine protein kinase
EONCEDMH_00996 7.9e-100 kcsA P Ion transport protein
EONCEDMH_00997 1.9e-116 yvqF S Membrane
EONCEDMH_00998 9.7e-170 vraS 2.7.13.3 T Histidine kinase
EONCEDMH_00999 3.1e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EONCEDMH_01002 9.9e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EONCEDMH_01003 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
EONCEDMH_01004 4.7e-185 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
EONCEDMH_01005 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
EONCEDMH_01006 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EONCEDMH_01007 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EONCEDMH_01008 5.8e-187 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EONCEDMH_01009 1.8e-180 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
EONCEDMH_01010 9.2e-283 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
EONCEDMH_01011 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
EONCEDMH_01012 6.5e-99 2.3.1.128 K Acetyltransferase GNAT Family
EONCEDMH_01013 1.7e-279 S Protein of unknown function (DUF3114)
EONCEDMH_01015 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
EONCEDMH_01016 1.4e-296 V abc transporter atp-binding protein
EONCEDMH_01017 0.0 V abc transporter atp-binding protein
EONCEDMH_01018 6.5e-186 XK27_10075 S abc transporter atp-binding protein
EONCEDMH_01019 2.9e-10
EONCEDMH_01021 1.7e-68 3.4.21.110 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EONCEDMH_01022 5.2e-297 S dextransucrase activity
EONCEDMH_01023 0.0 M Putative cell wall binding repeat
EONCEDMH_01024 3.1e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EONCEDMH_01025 7.3e-101 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EONCEDMH_01026 3.7e-180 S dextransucrase activity
EONCEDMH_01027 3.1e-92 S dextransucrase activity
EONCEDMH_01028 2.2e-236 S dextransucrase activity
EONCEDMH_01029 8.9e-238 M Putative cell wall binding repeat
EONCEDMH_01030 5.2e-23 S dextransucrase activity
EONCEDMH_01031 9.1e-36 M Putative cell wall binding repeat
EONCEDMH_01032 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
EONCEDMH_01033 1.2e-253 S dextransucrase activity
EONCEDMH_01035 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
EONCEDMH_01036 1.2e-113 yhfC S Putative membrane peptidase family (DUF2324)
EONCEDMH_01037 1.1e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
EONCEDMH_01038 4.6e-15 S integral membrane protein
EONCEDMH_01040 4.5e-07 S Enterocin A Immunity
EONCEDMH_01041 0.0 pepO 3.4.24.71 O Peptidase family M13
EONCEDMH_01042 2.1e-33 S Immunity protein 41
EONCEDMH_01043 6e-125 T Ser Thr phosphatase family protein
EONCEDMH_01044 0.0 M Putative cell wall binding repeat
EONCEDMH_01045 1.3e-227 thrE K Psort location CytoplasmicMembrane, score
EONCEDMH_01046 1.4e-176 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
EONCEDMH_01047 3.2e-93 dhaL 2.7.1.121 S Dihydroxyacetone kinase
EONCEDMH_01048 1.4e-57 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
EONCEDMH_01049 1.6e-177 XK27_10475 S oxidoreductase
EONCEDMH_01050 3.8e-196 gldA 1.1.1.6 C glycerol dehydrogenase
EONCEDMH_01052 1.1e-283 XK27_07020 S Belongs to the UPF0371 family
EONCEDMH_01053 1.7e-203 vex1 V Efflux ABC transporter, permease protein
EONCEDMH_01054 1.9e-107 vex2 V abc transporter atp-binding protein
EONCEDMH_01055 1.1e-232 vex3 V Efflux ABC transporter, permease protein
EONCEDMH_01056 1.5e-115 K Response regulator receiver domain protein
EONCEDMH_01057 7.2e-226 vncS 2.7.13.3 T Histidine kinase
EONCEDMH_01058 4.2e-308 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
EONCEDMH_01059 2.4e-49 L COG1943 Transposase and inactivated derivatives
EONCEDMH_01060 2.6e-151 galR K Transcriptional regulator
EONCEDMH_01061 1.1e-220 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EONCEDMH_01062 8.6e-284 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
EONCEDMH_01063 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EONCEDMH_01064 7.6e-202 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
EONCEDMH_01065 0.0 lacS G transporter
EONCEDMH_01066 0.0 lacL 3.2.1.23 G -beta-galactosidase
EONCEDMH_01067 1.4e-209 S Tetratricopeptide repeat
EONCEDMH_01068 9.2e-158 yvgN C reductase
EONCEDMH_01069 5.5e-30 XK27_10490
EONCEDMH_01070 1.3e-38 DJ nuclease activity
EONCEDMH_01071 1.1e-103 yoaK S Protein of unknown function (DUF1275)
EONCEDMH_01072 1.7e-108 drgA C nitroreductase
EONCEDMH_01073 1.9e-124 T Xre family transcriptional regulator
EONCEDMH_01074 4e-148 T PhoQ Sensor
EONCEDMH_01075 2.5e-45 S Domain of unknown function (DUF4352)
EONCEDMH_01076 8.1e-129 S ABC-2 family transporter protein
EONCEDMH_01077 3.7e-168 bcrA V abc transporter atp-binding protein
EONCEDMH_01078 8.7e-224 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EONCEDMH_01079 7e-153 E Alpha/beta hydrolase of unknown function (DUF915)
EONCEDMH_01080 7.5e-74 ywnA K Transcriptional regulator
EONCEDMH_01081 3.2e-150 1.13.11.2 S glyoxalase
EONCEDMH_01082 6.7e-110 XK27_02070 S nitroreductase
EONCEDMH_01083 7.2e-172 ydhF S Aldo keto reductase
EONCEDMH_01084 5.3e-96 K WHG domain
EONCEDMH_01085 2.3e-122 V abc transporter atp-binding protein
EONCEDMH_01086 7.3e-206 P FtsX-like permease family
EONCEDMH_01087 3.1e-14 XK27_10130
EONCEDMH_01089 2e-42 S Sugar efflux transporter for intercellular exchange
EONCEDMH_01090 1e-84 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
EONCEDMH_01091 1.4e-176 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
EONCEDMH_01092 1.8e-164 ET ABC transporter substrate-binding protein
EONCEDMH_01093 1.3e-109 ytmL P ABC transporter (Permease
EONCEDMH_01094 2.1e-112 yxeN P ABC transporter, permease protein
EONCEDMH_01095 2.1e-137 tcyC2 3.6.3.21 E abc transporter atp-binding protein
EONCEDMH_01096 0.0 S dextransucrase activity
EONCEDMH_01097 4.3e-213 yfnA E amino acid
EONCEDMH_01098 1.5e-50 XK27_01300 P Protein conserved in bacteria
EONCEDMH_01099 2.3e-28 S Carbohydrate-binding domain-containing protein Cthe_2159
EONCEDMH_01100 5.9e-15 csbD K CsbD-like
EONCEDMH_01101 1.7e-100 S Protein of unknown function (DUF421)
EONCEDMH_01102 3.2e-56 S Protein of unknown function (DUF3290)
EONCEDMH_01103 8.7e-181 manA 5.3.1.8 G mannose-6-phosphate isomerase
EONCEDMH_01104 9.2e-229 brnQ E Component of the transport system for branched-chain amino acids
EONCEDMH_01105 1.2e-125 T ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EONCEDMH_01106 0.0 S Domain of unknown function DUF87
EONCEDMH_01107 1.2e-31 T DNase/tRNase domain of colicin-like bacteriocin
EONCEDMH_01108 1.6e-13
EONCEDMH_01109 1.2e-177 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EONCEDMH_01111 1.1e-242 norM V Multidrug efflux pump
EONCEDMH_01112 3.7e-143 K sequence-specific DNA binding
EONCEDMH_01113 5.7e-278 V (ABC) transporter
EONCEDMH_01114 1.2e-222 pbuX F xanthine permease
EONCEDMH_01115 6.7e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EONCEDMH_01116 5.4e-124 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EONCEDMH_01117 4e-165 T Histidine kinase
EONCEDMH_01118 1.6e-132 macB2 V ABC transporter, ATP-binding protein
EONCEDMH_01119 0.0 V ABC transporter (permease)
EONCEDMH_01120 6.1e-93 XK27_05000 S metal cluster binding
EONCEDMH_01121 7.6e-30 liaI KT membrane
EONCEDMH_01122 7e-15 liaI KT membrane
EONCEDMH_01123 2.2e-154 XK27_09825 V abc transporter atp-binding protein
EONCEDMH_01124 2.2e-115 yvfS V Transporter
EONCEDMH_01125 6.1e-25 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
EONCEDMH_01126 3.6e-154
EONCEDMH_01127 1.9e-27 3.6.1.55 F NUDIX domain
EONCEDMH_01128 4.1e-79 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EONCEDMH_01129 3.5e-271 S Protein of unknown function (DUF2971)
EONCEDMH_01130 3.5e-43
EONCEDMH_01131 1.2e-17
EONCEDMH_01133 3e-33 M translation initiation factor activity
EONCEDMH_01134 4e-21 P ABC transporter transmembrane region
EONCEDMH_01135 2e-82 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
EONCEDMH_01136 5.1e-165 yocS S Transporter
EONCEDMH_01139 6.7e-159 XK27_09825 V abc transporter atp-binding protein
EONCEDMH_01140 2e-132 yvfS V ABC-2 type transporter
EONCEDMH_01141 2e-181 desK 2.7.13.3 T Histidine kinase
EONCEDMH_01142 1.5e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EONCEDMH_01143 1.2e-206 S Protein of unknown function DUF262
EONCEDMH_01144 8.8e-125 S Protein of unknown function DUF262
EONCEDMH_01145 4.3e-85 yfjR K regulation of single-species biofilm formation
EONCEDMH_01148 1.2e-185 S abc transporter atp-binding protein
EONCEDMH_01149 2.4e-142 S ABC-2 family transporter protein
EONCEDMH_01150 1.1e-141 S ABC-2 family transporter protein
EONCEDMH_01151 1.3e-36 yfiQ K -acetyltransferase
EONCEDMH_01152 1.7e-48
EONCEDMH_01153 6e-142 K sequence-specific DNA binding
EONCEDMH_01154 9.5e-95 S ABC-2 family transporter protein
EONCEDMH_01155 6e-149 V ABC transporter, ATP-binding protein
EONCEDMH_01156 5.7e-129 K sequence-specific DNA binding
EONCEDMH_01157 2.3e-82 3.4.21.89 S RDD family
EONCEDMH_01158 1.8e-159 yjlA EG membrane
EONCEDMH_01159 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
EONCEDMH_01160 1e-223 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
EONCEDMH_01161 3.7e-42 ulaB 2.7.1.194 G COG3414 Phosphotransferase system galactitol-specific IIB component
EONCEDMH_01162 2e-215 ulaA 2.7.1.194 S PTS system sugar-specific permease component
EONCEDMH_01163 1.2e-123 tktN 2.2.1.1 G 1-deoxy-D-xylulose-5-phosphate synthase
EONCEDMH_01164 2.1e-123 tktC 2.2.1.1 G Transketolase, pyrimidine binding domain
EONCEDMH_01165 5.8e-147 sdaAA 4.3.1.17 E L-serine dehydratase
EONCEDMH_01166 3e-119 sdaAB 4.3.1.17 E L-serine dehydratase
EONCEDMH_01167 1.5e-18 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
EONCEDMH_01168 3.2e-98 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
EONCEDMH_01169 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EONCEDMH_01170 1.5e-36 L RePlication protein
EONCEDMH_01171 2.6e-36 P (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EONCEDMH_01172 7.4e-278 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
EONCEDMH_01173 2.6e-152 L PFAM Integrase catalytic region
EONCEDMH_01174 4e-270 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EONCEDMH_01175 5.2e-87 pat 2.3.1.183 M acetyltransferase
EONCEDMH_01176 5.7e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EONCEDMH_01177 3.3e-118 alkD L DNA alkylation repair enzyme
EONCEDMH_01178 3.6e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EONCEDMH_01179 1.7e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EONCEDMH_01180 9.3e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EONCEDMH_01181 0.0 smc D Required for chromosome condensation and partitioning
EONCEDMH_01182 4e-77 S Protein of unknown function (DUF3278)
EONCEDMH_01183 1e-22 WQ51_00220 K Helix-turn-helix domain
EONCEDMH_01184 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EONCEDMH_01185 5.4e-92 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EONCEDMH_01186 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EONCEDMH_01188 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
EONCEDMH_01189 2.2e-235 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EONCEDMH_01191 1.6e-83 S ECF-type riboflavin transporter, S component
EONCEDMH_01192 1.6e-141 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
EONCEDMH_01193 1.1e-79 XK27_01265 S ECF-type riboflavin transporter, S component
EONCEDMH_01194 1.1e-294 yfmM S abc transporter atp-binding protein
EONCEDMH_01195 3.9e-254 noxE P NADH oxidase
EONCEDMH_01196 4.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
EONCEDMH_01197 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EONCEDMH_01198 7.9e-132 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
EONCEDMH_01199 8.2e-72 yaeR E COG0346 Lactoylglutathione lyase and related lyases
EONCEDMH_01200 1.2e-161 ypuA S secreted protein
EONCEDMH_01201 5.7e-228 mntH P Mn2 and Fe2 transporters of the NRAMP family
EONCEDMH_01202 4.4e-45 rpmE2 J 50S ribosomal protein L31
EONCEDMH_01203 6.8e-170 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
EONCEDMH_01204 9.3e-175 nrnA 3.1.13.3, 3.1.3.7 S domain protein
EONCEDMH_01205 1.3e-150 gst O Glutathione S-transferase
EONCEDMH_01206 1.9e-181 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EONCEDMH_01207 7.8e-111 tdk 2.7.1.21 F thymidine kinase
EONCEDMH_01208 2.4e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EONCEDMH_01209 2.2e-143 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EONCEDMH_01210 8.8e-102 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
EONCEDMH_01211 2.3e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EONCEDMH_01212 8.4e-179 ndpA S 37-kD nucleoid-associated bacterial protein
EONCEDMH_01213 6.4e-100 pvaA M lytic transglycosylase activity
EONCEDMH_01214 4.2e-290 yfiB1 V abc transporter atp-binding protein
EONCEDMH_01215 0.0 XK27_10035 V abc transporter atp-binding protein
EONCEDMH_01216 9.3e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EONCEDMH_01217 3.6e-235 dltB M Membrane protein involved in D-alanine export
EONCEDMH_01218 8.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EONCEDMH_01219 6.3e-235 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EONCEDMH_01220 1.4e-91 G Citrate lyase beta subunit
EONCEDMH_01221 1.5e-74 3.1.3.12 S hydrolases of the HAD superfamily
EONCEDMH_01222 0.0 3.6.3.8 P cation transport ATPase
EONCEDMH_01223 1.8e-89 T proteins involved in stress response, homologs of TerZ and
EONCEDMH_01224 2e-76 T proteins involved in stress response, homologs of TerZ and
EONCEDMH_01225 1.2e-90 T proteins involved in stress response, homologs of TerZ and
EONCEDMH_01226 9.5e-166 yceH P Belongs to the TelA family
EONCEDMH_01227 3.1e-199 yceG S Putative component of 'biosynthetic module'
EONCEDMH_01228 3.4e-144 stiP J Phosphoribosyl transferase (PRTase)
EONCEDMH_01229 9.4e-113 apt 2.4.2.22, 2.4.2.7 F TRSP domain C terminus to PRTase_2
EONCEDMH_01230 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
EONCEDMH_01232 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EONCEDMH_01233 2.4e-164 metF 1.5.1.20 E reductase
EONCEDMH_01234 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
EONCEDMH_01235 2.7e-92 panT S ECF transporter, substrate-specific component
EONCEDMH_01236 2.4e-90 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EONCEDMH_01237 3.1e-111 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
EONCEDMH_01238 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
EONCEDMH_01239 2.1e-120 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EONCEDMH_01240 3.8e-233 T PhoQ Sensor
EONCEDMH_01241 2.3e-29 rpsT J Binds directly to 16S ribosomal RNA
EONCEDMH_01242 2.6e-169 coaA 2.7.1.33 F Pantothenic acid kinase
EONCEDMH_01243 3.5e-103 rsmC 2.1.1.172 J Methyltransferase small domain protein
EONCEDMH_01244 1.7e-227 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
EONCEDMH_01245 7.9e-112 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EONCEDMH_01246 9.1e-63 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
EONCEDMH_01247 1.8e-190 tcsA S membrane
EONCEDMH_01248 3.5e-280 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
EONCEDMH_01249 2.3e-177 yufP S Belongs to the binding-protein-dependent transport system permease family
EONCEDMH_01250 5e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
EONCEDMH_01251 8.9e-113 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
EONCEDMH_01252 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
EONCEDMH_01253 6.6e-76 ypmB S Protein conserved in bacteria
EONCEDMH_01254 1.4e-212 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
EONCEDMH_01255 5.4e-261 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
EONCEDMH_01256 1.4e-18
EONCEDMH_01257 2.4e-199 pmrB EGP Major facilitator Superfamily
EONCEDMH_01258 2.3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
EONCEDMH_01259 2.6e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EONCEDMH_01260 8.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
EONCEDMH_01261 4.6e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
EONCEDMH_01262 1.4e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
EONCEDMH_01263 8.5e-197 D nuclear chromosome segregation
EONCEDMH_01264 1.9e-133 yejC S cyclic nucleotide-binding protein
EONCEDMH_01265 8.5e-162 rapZ S Displays ATPase and GTPase activities
EONCEDMH_01266 1.4e-181 ybhK S Required for morphogenesis under gluconeogenic growth conditions
EONCEDMH_01267 5.7e-161 whiA K May be required for sporulation
EONCEDMH_01268 2.2e-273 pepD E Dipeptidase
EONCEDMH_01269 4.8e-143 XK27_10720 D peptidase activity
EONCEDMH_01270 1.4e-289 adcA P Belongs to the bacterial solute-binding protein 9 family
EONCEDMH_01271 3.4e-09
EONCEDMH_01273 2.4e-168 yeiH S Membrane
EONCEDMH_01274 9.3e-127 mur1 3.4.17.14, 3.5.1.28 NU muramidase
EONCEDMH_01275 2.2e-165 cpsY K Transcriptional regulator
EONCEDMH_01276 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EONCEDMH_01277 6.6e-59 phnA P Alkylphosphonate utilization operon protein PhnA
EONCEDMH_01278 3.1e-105 artQ P ABC transporter (Permease
EONCEDMH_01279 1.4e-110 glnQ 3.6.3.21 E abc transporter atp-binding protein
EONCEDMH_01280 9.7e-155 aatB ET ABC transporter substrate-binding protein
EONCEDMH_01281 6.7e-270 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EONCEDMH_01282 2.9e-50
EONCEDMH_01283 1.8e-44
EONCEDMH_01284 4.2e-189 adhP 1.1.1.1 C alcohol dehydrogenase
EONCEDMH_01285 6.7e-99 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EONCEDMH_01286 2.3e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
EONCEDMH_01287 7.7e-126 gntR1 K transcriptional
EONCEDMH_01288 4.9e-54 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EONCEDMH_01289 1.6e-272 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EONCEDMH_01290 2.1e-83
EONCEDMH_01291 6e-83 niaR S small molecule binding protein (contains 3H domain)
EONCEDMH_01292 2.4e-127 K DNA-binding helix-turn-helix protein
EONCEDMH_01293 9.4e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EONCEDMH_01294 3.5e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EONCEDMH_01295 1.2e-152 GK ROK family
EONCEDMH_01296 4.6e-157 dprA LU DNA protecting protein DprA
EONCEDMH_01297 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EONCEDMH_01298 2.1e-83 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
EONCEDMH_01299 2.6e-52 V ABC-2 family transporter protein
EONCEDMH_01301 2.1e-146 S TraX protein
EONCEDMH_01302 5.1e-119 KT Transcriptional regulatory protein, C terminal
EONCEDMH_01303 3.2e-221 T PhoQ Sensor
EONCEDMH_01304 6.2e-257 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EONCEDMH_01305 4.7e-221 XK27_05470 E Methionine synthase
EONCEDMH_01306 5.5e-71 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
EONCEDMH_01307 1e-42 pspE P Rhodanese-like protein
EONCEDMH_01308 4e-136 IQ Acetoin reductase
EONCEDMH_01310 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EONCEDMH_01313 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
EONCEDMH_01314 3.1e-130 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
EONCEDMH_01315 2.3e-67 mgrA K Transcriptional regulator, MarR family
EONCEDMH_01316 4e-145 1.6.5.2 GM NmrA family
EONCEDMH_01317 5e-128 proV E abc transporter atp-binding protein
EONCEDMH_01318 2e-259 proWX P ABC transporter
EONCEDMH_01319 2.4e-139 S Phenazine biosynthesis protein
EONCEDMH_01320 6.3e-92 2.7.7.65 T Psort location CytoplasmicMembrane, score
EONCEDMH_01321 1.1e-131 cbiQ P cobalt transport
EONCEDMH_01322 1e-156 P ATPase activity
EONCEDMH_01323 1.8e-150 cbiO2 P ABC transporter, ATP-binding protein
EONCEDMH_01324 1.9e-62 pnuC H nicotinamide mononucleotide transporter
EONCEDMH_01325 3.8e-67 K Transcriptional regulator
EONCEDMH_01326 3e-177 1.1.1.1 C nadph quinone reductase
EONCEDMH_01327 2.2e-151 I Alpha/beta hydrolase family
EONCEDMH_01328 1.1e-148 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EONCEDMH_01329 4.9e-38
EONCEDMH_01330 3.6e-58 S Protein of unknown function with HXXEE motif
EONCEDMH_01331 3.5e-94 K Transcriptional regulator, TetR family
EONCEDMH_01332 1.5e-153 czcD P cation diffusion facilitator family transporter
EONCEDMH_01333 2.2e-188 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
EONCEDMH_01334 2.3e-187 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
EONCEDMH_01335 6.2e-64 copY K Copper transport repressor, CopY TcrY family
EONCEDMH_01336 1.2e-64 silP 1.9.3.1, 3.6.3.54 S cog cog4633
EONCEDMH_01337 0.0 copA 3.6.3.54 P P-type ATPase
EONCEDMH_01338 2.5e-122 spxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
EONCEDMH_01339 3.5e-144 G protein with an alpha beta hydrolase fold
EONCEDMH_01340 1e-125 ybhF_2 V abc transporter atp-binding protein
EONCEDMH_01341 8.7e-177 ybhR V ABC-2 family transporter protein
EONCEDMH_01342 1.5e-109 K Bacterial regulatory proteins, tetR family
EONCEDMH_01343 3e-139 2.4.2.3 F Phosphorylase superfamily
EONCEDMH_01344 5.4e-110 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
EONCEDMH_01345 0.0 V Type III restriction enzyme, res subunit
EONCEDMH_01346 1.1e-173 yclQ P ABC-type enterochelin transport system, periplasmic component
EONCEDMH_01347 3.1e-232 dinF V Mate efflux family protein
EONCEDMH_01348 4e-276 S Psort location CytoplasmicMembrane, score
EONCEDMH_01349 6.2e-307 FbpA K RNA-binding protein homologous to eukaryotic snRNP
EONCEDMH_01350 8.8e-134 S TraX protein
EONCEDMH_01351 6.8e-93 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
EONCEDMH_01352 3.8e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
EONCEDMH_01353 5.5e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EONCEDMH_01354 5e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EONCEDMH_01355 1.7e-111 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EONCEDMH_01356 1.4e-230 nylA 3.5.1.4 J Belongs to the amidase family
EONCEDMH_01357 6e-149 yckB ET Belongs to the bacterial solute-binding protein 3 family
EONCEDMH_01358 9.3e-81 yecS P ABC transporter (Permease
EONCEDMH_01359 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
EONCEDMH_01360 7.1e-170 bglC K Transcriptional regulator
EONCEDMH_01361 8.9e-243 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EONCEDMH_01362 4.2e-237 agcS E (Alanine) symporter
EONCEDMH_01363 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
EONCEDMH_01364 5.6e-239 metY 2.5.1.49 E o-acetylhomoserine
EONCEDMH_01365 4.7e-137 S haloacid dehalogenase-like hydrolase
EONCEDMH_01366 4.2e-86 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EONCEDMH_01367 4e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
EONCEDMH_01368 8e-35 M1-755 P Hemerythrin HHE cation binding domain protein
EONCEDMH_01369 1.5e-234 XK27_04775 S hemerythrin HHE cation binding domain
EONCEDMH_01370 2.1e-146 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EONCEDMH_01371 7.4e-169 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
EONCEDMH_01372 7.9e-70 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EONCEDMH_01373 3e-44 yktA S Belongs to the UPF0223 family
EONCEDMH_01374 2.1e-140 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
EONCEDMH_01375 5.3e-245 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
EONCEDMH_01376 2.6e-155 pstS P phosphate
EONCEDMH_01377 4.7e-155 pstC P probably responsible for the translocation of the substrate across the membrane
EONCEDMH_01378 9.1e-156 pstA P phosphate transport system permease
EONCEDMH_01379 1.7e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EONCEDMH_01380 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EONCEDMH_01381 1.2e-112 phoU P Plays a role in the regulation of phosphate uptake
EONCEDMH_01382 0.0 pepN 3.4.11.2 E aminopeptidase
EONCEDMH_01383 6.2e-191 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
EONCEDMH_01384 6.1e-185 lplA 6.3.1.20 H Lipoate-protein ligase
EONCEDMH_01385 5.2e-39
EONCEDMH_01386 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
EONCEDMH_01387 2.8e-298 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
EONCEDMH_01388 1.7e-171 malR K Transcriptional regulator
EONCEDMH_01389 3.9e-229 malX G ABC transporter
EONCEDMH_01390 8.2e-249 malF P ABC transporter (Permease
EONCEDMH_01391 2.2e-151 malG P ABC transporter (Permease
EONCEDMH_01392 1.8e-212 msmX P Belongs to the ABC transporter superfamily
EONCEDMH_01393 1.9e-23 tatA U protein secretion
EONCEDMH_01394 2.2e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EONCEDMH_01395 3.1e-290 ywbL P COG0672 High-affinity Fe2 Pb2 permease
EONCEDMH_01396 2.2e-229 ycdB P peroxidase
EONCEDMH_01397 1.7e-146 ycdO P periplasmic lipoprotein involved in iron transport
EONCEDMH_01398 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EONCEDMH_01399 6.4e-35 lytC 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
EONCEDMH_01401 8.6e-87 sigH K DNA-templated transcription, initiation
EONCEDMH_01402 6e-135 ykuT M mechanosensitive ion channel
EONCEDMH_01403 5.8e-228 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EONCEDMH_01404 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EONCEDMH_01405 3.7e-309 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EONCEDMH_01406 6.4e-84 XK27_03960 S Protein of unknown function (DUF3013)
EONCEDMH_01407 2.2e-78 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
EONCEDMH_01408 1.3e-57 XK27_02675 K Acetyltransferase GNAT Family
EONCEDMH_01409 3.5e-177 prmA J Ribosomal protein L11 methyltransferase
EONCEDMH_01410 7.7e-132 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EONCEDMH_01411 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
EONCEDMH_01412 9.1e-83 nrdI F Belongs to the NrdI family
EONCEDMH_01413 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EONCEDMH_01414 9.7e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EONCEDMH_01415 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
EONCEDMH_01416 8.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EONCEDMH_01417 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EONCEDMH_01418 1.3e-111 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
EONCEDMH_01419 3e-191 yhjX P Major Facilitator
EONCEDMH_01420 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EONCEDMH_01421 1.4e-177 D nuclear chromosome segregation
EONCEDMH_01422 2.2e-123 glnQ E abc transporter atp-binding protein
EONCEDMH_01423 4.3e-270 glnP P ABC transporter
EONCEDMH_01424 3.4e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
EONCEDMH_01425 2.4e-17 S Protein of unknown function (DUF3021)
EONCEDMH_01426 2.9e-123 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
EONCEDMH_01427 5.7e-182 tagO 2.7.8.33, 2.7.8.35 M transferase
EONCEDMH_01428 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
EONCEDMH_01429 6.9e-234 sufD O assembly protein SufD
EONCEDMH_01430 3.4e-233 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EONCEDMH_01431 8e-73 nifU C SUF system FeS assembly protein, NifU family
EONCEDMH_01432 2.9e-273 sufB O assembly protein SufB
EONCEDMH_01433 9.4e-27
EONCEDMH_01434 2.1e-157 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EONCEDMH_01435 2.8e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EONCEDMH_01436 1.7e-70 adcR K transcriptional
EONCEDMH_01437 9.2e-135 adcC P ABC transporter, ATP-binding protein
EONCEDMH_01438 4.3e-128 adcB P ABC transporter (Permease
EONCEDMH_01439 5.5e-159 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
EONCEDMH_01440 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
EONCEDMH_01441 4.6e-154 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
EONCEDMH_01442 4.2e-253 pgi 5.3.1.9 G Belongs to the GPI family
EONCEDMH_01443 1.4e-142 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EONCEDMH_01444 0.0 srlM 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
EONCEDMH_01445 6.8e-84 gutM K phosphoenolpyruvate-dependent sugar phosphotransferase system
EONCEDMH_01446 1.1e-95 srlA G PTS system glucitol sorbitol-specific
EONCEDMH_01447 3.8e-179 srlE 2.7.1.198 G PTS sorbitol transporter subunit IIB
EONCEDMH_01448 4.2e-59 srlB 2.7.1.198 G sorbitol-specific, IIA component
EONCEDMH_01449 8.1e-16 tnp* L An automated process has identified a potential problem with this gene model
EONCEDMH_01450 9.2e-59 L MULE transposase domain
EONCEDMH_01451 1.1e-108 L Transposase IS116 IS110 IS902
EONCEDMH_01452 1.3e-305 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EONCEDMH_01453 8.2e-219 L the current gene model (or a revised gene model) may contain a frame shift
EONCEDMH_01454 1.4e-153 Z012_04635 K sequence-specific DNA binding
EONCEDMH_01455 1.1e-276 V ABC transporter
EONCEDMH_01456 6.1e-126 yeeN K transcriptional regulatory protein
EONCEDMH_01457 2e-47 yajC U protein transport
EONCEDMH_01458 5.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EONCEDMH_01459 4.6e-143 cdsA 2.7.7.41 S Belongs to the CDS family
EONCEDMH_01460 1.4e-229 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
EONCEDMH_01461 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EONCEDMH_01462 0.0 WQ51_06230 S ABC transporter
EONCEDMH_01463 3e-142 cmpC S abc transporter atp-binding protein
EONCEDMH_01464 4.9e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EONCEDMH_01465 6.5e-285 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EONCEDMH_01467 1.9e-44
EONCEDMH_01468 5.8e-55 S TM2 domain
EONCEDMH_01469 1.4e-161 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EONCEDMH_01470 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EONCEDMH_01471 6.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
EONCEDMH_01472 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
EONCEDMH_01473 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
EONCEDMH_01474 6.9e-65 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
EONCEDMH_01475 2.8e-143 cof S Sucrose-6F-phosphate phosphohydrolase
EONCEDMH_01476 3.6e-132 glcR K transcriptional regulator (DeoR family)
EONCEDMH_01477 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
EONCEDMH_01478 8.4e-73 K transcriptional
EONCEDMH_01479 6.6e-221 S COG1073 Hydrolases of the alpha beta superfamily
EONCEDMH_01480 6.8e-156 cylA V abc transporter atp-binding protein
EONCEDMH_01481 1e-132 cylB V ABC-2 type transporter
EONCEDMH_01482 1.3e-73 K COG3279 Response regulator of the LytR AlgR family
EONCEDMH_01483 4.8e-30 S Protein of unknown function (DUF3021)
EONCEDMH_01484 1.4e-114 mta K Transcriptional
EONCEDMH_01485 8.1e-120 yhcA V abc transporter atp-binding protein
EONCEDMH_01486 8.3e-208 macB_2 V FtsX-like permease family
EONCEDMH_01487 9.7e-272 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EONCEDMH_01488 2.2e-148 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
EONCEDMH_01489 2e-71 yhaI S Protein of unknown function (DUF805)
EONCEDMH_01490 3.8e-254 pepC 3.4.22.40 E aminopeptidase
EONCEDMH_01491 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EONCEDMH_01492 4.3e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EONCEDMH_01493 1.7e-93 ypsA S Belongs to the UPF0398 family
EONCEDMH_01494 2.1e-36 gpsB D regulation of cell shape
EONCEDMH_01495 1.8e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
EONCEDMH_01496 1e-279 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
EONCEDMH_01497 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
EONCEDMH_01498 4.8e-22
EONCEDMH_01499 3.4e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
EONCEDMH_01500 2.7e-85 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
EONCEDMH_01501 7.2e-294 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EONCEDMH_01502 4.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EONCEDMH_01503 1.4e-162 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EONCEDMH_01504 2.5e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
EONCEDMH_01505 1.3e-126 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EONCEDMH_01506 7.3e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
EONCEDMH_01507 5e-101 ybhL S Belongs to the BI1 family
EONCEDMH_01508 3.2e-12 ycdA S Domain of unknown function (DUF4352)
EONCEDMH_01509 3.1e-242 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EONCEDMH_01510 4.1e-90 K transcriptional regulator
EONCEDMH_01511 3.5e-36 yneF S UPF0154 protein
EONCEDMH_01512 3.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
EONCEDMH_01513 6.2e-182 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EONCEDMH_01514 8.1e-96 XK27_09740 S Phosphoesterase
EONCEDMH_01515 2.7e-85 ykuL S CBS domain
EONCEDMH_01516 2.9e-126 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
EONCEDMH_01517 3.4e-121 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EONCEDMH_01518 1.2e-95 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EONCEDMH_01519 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EONCEDMH_01520 1.8e-257 trkH P Cation transport protein
EONCEDMH_01521 9.3e-245 trkA P Potassium transporter peripheral membrane component
EONCEDMH_01522 1.8e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EONCEDMH_01523 5.6e-87 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EONCEDMH_01524 1.7e-90 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
EONCEDMH_01525 2.7e-155 K sequence-specific DNA binding
EONCEDMH_01526 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
EONCEDMH_01527 5.4e-53 yhaI L Membrane
EONCEDMH_01528 2.9e-241 S Domain of unknown function (DUF4173)
EONCEDMH_01529 1.5e-94 ureI S AmiS/UreI family transporter
EONCEDMH_01530 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
EONCEDMH_01531 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
EONCEDMH_01532 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
EONCEDMH_01533 6.6e-78 ureE O enzyme active site formation
EONCEDMH_01534 3.8e-128 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
EONCEDMH_01535 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EONCEDMH_01536 7e-158 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
EONCEDMH_01537 7.9e-177 cbiM P PDGLE domain
EONCEDMH_01538 1.7e-134 P cobalt transport protein
EONCEDMH_01539 1.7e-128 cbiO P ABC transporter
EONCEDMH_01540 5.3e-137 ET ABC transporter substrate-binding protein
EONCEDMH_01541 7.8e-163 metQ M Belongs to the NlpA lipoprotein family
EONCEDMH_01542 2.5e-261 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
EONCEDMH_01543 1.1e-184 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EONCEDMH_01544 1.2e-99 metI P ABC transporter (Permease
EONCEDMH_01545 2.5e-209 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EONCEDMH_01546 3.5e-157 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
EONCEDMH_01547 6.7e-93 S UPF0397 protein
EONCEDMH_01548 2.6e-305 ykoD P abc transporter atp-binding protein
EONCEDMH_01549 3.2e-147 cbiQ P cobalt transport
EONCEDMH_01550 3.7e-117 ktrA P COG0569 K transport systems, NAD-binding component
EONCEDMH_01551 4e-235 P COG0168 Trk-type K transport systems, membrane components
EONCEDMH_01552 3.5e-126 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
EONCEDMH_01553 1.2e-89 yceD K metal-binding, possibly nucleic acid-binding protein
EONCEDMH_01554 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EONCEDMH_01555 3.3e-278 T PhoQ Sensor
EONCEDMH_01556 3e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EONCEDMH_01557 2.4e-212 dnaB L Replication initiation and membrane attachment
EONCEDMH_01558 4.4e-166 dnaI L Primosomal protein DnaI
EONCEDMH_01559 9.7e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
EONCEDMH_01560 7.7e-112
EONCEDMH_01561 6.2e-230 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EONCEDMH_01562 2.5e-62 manO S protein conserved in bacteria
EONCEDMH_01563 4e-167 manN G PTS system mannose fructose sorbose family IID component
EONCEDMH_01564 1.2e-114 manM G pts system
EONCEDMH_01565 4.9e-174 manL 2.7.1.191 G pts system
EONCEDMH_01566 5.9e-67 manO S Protein conserved in bacteria
EONCEDMH_01567 5.9e-158 manN G PTS system mannose fructose sorbose family IID component
EONCEDMH_01568 5.7e-133 manY G pts system
EONCEDMH_01569 6.2e-169 manL 2.7.1.191 G pts system
EONCEDMH_01570 3.2e-138 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
EONCEDMH_01571 7.8e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
EONCEDMH_01572 1.6e-247 pbuO S permease
EONCEDMH_01573 2.7e-76 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
EONCEDMH_01574 2.6e-86 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
EONCEDMH_01575 5.9e-185 brpA K Transcriptional
EONCEDMH_01576 1.1e-80 rimP S Required for maturation of 30S ribosomal subunits
EONCEDMH_01577 2.4e-196 nusA K Participates in both transcription termination and antitermination
EONCEDMH_01578 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
EONCEDMH_01579 8e-42 ylxQ J ribosomal protein
EONCEDMH_01580 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EONCEDMH_01581 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EONCEDMH_01582 2.2e-99 yvdD 3.2.2.10 S Belongs to the LOG family
EONCEDMH_01583 3.3e-188 femA 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
EONCEDMH_01584 2.1e-266 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EONCEDMH_01585 5.2e-279 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
EONCEDMH_01586 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
EONCEDMH_01587 1.1e-200 metB 2.5.1.48, 4.4.1.8 E cystathionine
EONCEDMH_01588 1.3e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
EONCEDMH_01589 2.6e-264 L Transposase
EONCEDMH_01590 7.1e-306 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
EONCEDMH_01591 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
EONCEDMH_01592 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EONCEDMH_01593 3.7e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EONCEDMH_01594 9.2e-72 ylbF S Belongs to the UPF0342 family
EONCEDMH_01595 5.4e-46 ylbG S UPF0298 protein
EONCEDMH_01596 8.5e-210 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
EONCEDMH_01597 1.2e-144 livH E Belongs to the binding-protein-dependent transport system permease family
EONCEDMH_01598 4.9e-139 livM E Belongs to the binding-protein-dependent transport system permease family
EONCEDMH_01599 4e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
EONCEDMH_01600 5.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
EONCEDMH_01601 2.5e-110 acuB S CBS domain
EONCEDMH_01602 2e-166 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EONCEDMH_01603 2.9e-108 yvyE 3.4.13.9 S YigZ family
EONCEDMH_01604 5.7e-239 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EONCEDMH_01605 1.2e-99 comFC K competence protein
EONCEDMH_01606 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EONCEDMH_01607 2e-224 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
EONCEDMH_01608 3.4e-14 rpmH J Ribosomal protein L34
EONCEDMH_01609 1.2e-97 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
EONCEDMH_01610 2.4e-99 K Transcriptional regulator
EONCEDMH_01611 3e-150 jag S RNA-binding protein
EONCEDMH_01612 9.7e-147 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EONCEDMH_01613 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
EONCEDMH_01614 2.3e-262 argH 4.3.2.1 E Argininosuccinate lyase
EONCEDMH_01615 1.7e-229 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
EONCEDMH_01616 4.7e-129 fasA KT Response regulator of the LytR AlgR family
EONCEDMH_01617 4.7e-225 fasC T protein histidine kinase activity
EONCEDMH_01618 9.3e-210 hpk9 2.7.13.3 T protein histidine kinase activity
EONCEDMH_01619 1.5e-150 hpk9 2.7.13.3 T protein histidine kinase activity
EONCEDMH_01620 1.1e-229 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
EONCEDMH_01621 1.6e-271 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EONCEDMH_01622 0.0 amiA E ABC transporter, substrate-binding protein, family 5
EONCEDMH_01623 5.3e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EONCEDMH_01624 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EONCEDMH_01625 1.2e-50 S Protein of unknown function (DUF3397)
EONCEDMH_01626 1e-87 cah 4.2.1.1 P Reversible hydration of carbon dioxide
EONCEDMH_01627 1.6e-126 WQ51_05710 S Mitochondrial biogenesis AIM24
EONCEDMH_01628 1.5e-225 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EONCEDMH_01629 1e-73 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
EONCEDMH_01630 3.2e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
EONCEDMH_01631 8.2e-108 XK27_09620 S FMN reductase (NADPH) activity
EONCEDMH_01632 7.9e-230 XK27_09615 C reductase
EONCEDMH_01633 1.6e-140 fnt P Formate nitrite transporter
EONCEDMH_01634 6.7e-96 XK27_08585 S Psort location CytoplasmicMembrane, score
EONCEDMH_01635 9.1e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
EONCEDMH_01636 5.7e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
EONCEDMH_01637 9.1e-116 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
EONCEDMH_01638 5.9e-94 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EONCEDMH_01639 7.4e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
EONCEDMH_01640 5.3e-58 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
EONCEDMH_01641 1.4e-128 S HAD hydrolase, family IA, variant
EONCEDMH_01642 3.5e-157 rrmA 2.1.1.187 Q methyltransferase
EONCEDMH_01646 5.1e-90 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EONCEDMH_01647 6.6e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EONCEDMH_01648 8.3e-37 yeeD O sulfur carrier activity
EONCEDMH_01649 6.1e-188 yeeE S Sulphur transport
EONCEDMH_01650 1.9e-112 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EONCEDMH_01651 1.3e-08 S NTF2 fold immunity protein
EONCEDMH_01652 2.3e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
EONCEDMH_01653 2e-08 XK27_10305 S Domain of unknown function (DUF4651)
EONCEDMH_01654 7e-203 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
EONCEDMH_01655 5.2e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EONCEDMH_01656 4e-100 S CAAX amino terminal protease family protein
EONCEDMH_01658 3.2e-105 V CAAX protease self-immunity
EONCEDMH_01659 1.5e-26 lanR K sequence-specific DNA binding
EONCEDMH_01660 7.5e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EONCEDMH_01661 1.5e-175 ytxK 2.1.1.72 L DNA methylase
EONCEDMH_01662 1.2e-12 comGF U Putative Competence protein ComGF
EONCEDMH_01663 1.3e-70 comGF U Competence protein ComGF
EONCEDMH_01664 1.8e-15 NU Type II secretory pathway pseudopilin
EONCEDMH_01665 6e-68 cglD NU Competence protein
EONCEDMH_01666 2.2e-43 comGC U Required for transformation and DNA binding
EONCEDMH_01667 1.7e-143 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EONCEDMH_01668 4.2e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EONCEDMH_01669 1e-68 S cog cog4699
EONCEDMH_01670 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EONCEDMH_01671 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EONCEDMH_01672 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EONCEDMH_01673 5.5e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EONCEDMH_01674 3.9e-195 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EONCEDMH_01675 2.2e-76 ilvN 2.2.1.6 E Acetolactate synthase
EONCEDMH_01676 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
EONCEDMH_01677 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
EONCEDMH_01681 4.2e-303 yloV S kinase related to dihydroxyacetone kinase
EONCEDMH_01682 1.4e-57 asp S cog cog1302
EONCEDMH_01683 1.9e-223 norN V Mate efflux family protein
EONCEDMH_01684 1e-276 thrC 4.2.3.1 E Threonine synthase
EONCEDMH_01687 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
EONCEDMH_01688 0.0 pepO 3.4.24.71 O Peptidase family M13
EONCEDMH_01689 6.8e-256 treC 3.2.1.93 GH13 G COG0366 Glycosidases
EONCEDMH_01690 5.1e-96 ywlG S Belongs to the UPF0340 family
EONCEDMH_01693 1.3e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
EONCEDMH_01695 4.3e-239 6.3.2.2 H gamma-glutamylcysteine synthetase
EONCEDMH_01696 4.4e-62 rplQ J ribosomal protein l17
EONCEDMH_01697 4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EONCEDMH_01698 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EONCEDMH_01699 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EONCEDMH_01700 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
EONCEDMH_01701 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EONCEDMH_01702 2.5e-115 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EONCEDMH_01703 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EONCEDMH_01704 5.7e-58 rplO J binds to the 23S rRNA
EONCEDMH_01705 1.9e-23 rpmD J ribosomal protein l30
EONCEDMH_01706 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EONCEDMH_01707 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EONCEDMH_01708 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EONCEDMH_01709 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EONCEDMH_01710 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EONCEDMH_01711 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EONCEDMH_01712 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EONCEDMH_01713 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EONCEDMH_01714 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EONCEDMH_01715 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
EONCEDMH_01716 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EONCEDMH_01717 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EONCEDMH_01718 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EONCEDMH_01719 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EONCEDMH_01720 6.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EONCEDMH_01721 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EONCEDMH_01722 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
EONCEDMH_01723 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EONCEDMH_01724 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
EONCEDMH_01725 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EONCEDMH_01726 0.0 XK27_09800 I Acyltransferase
EONCEDMH_01727 2.8e-35 XK27_09805 S MORN repeat protein
EONCEDMH_01728 2.6e-79 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EONCEDMH_01729 1e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EONCEDMH_01730 5e-90 adk 2.7.4.3 F topology modulation protein
EONCEDMH_01731 5.1e-82 S Short repeat of unknown function (DUF308)
EONCEDMH_01732 5e-90 K sequence-specific DNA binding
EONCEDMH_01733 1.5e-156 L Replication initiation factor
EONCEDMH_01734 1.9e-18 S Domain of unknown function (DUF3173)
EONCEDMH_01735 1e-212 int L Belongs to the 'phage' integrase family
EONCEDMH_01737 7.5e-236 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
EONCEDMH_01738 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
EONCEDMH_01739 6.3e-44 yrzL S Belongs to the UPF0297 family
EONCEDMH_01740 1.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EONCEDMH_01741 3.2e-44 yrzB S Belongs to the UPF0473 family
EONCEDMH_01742 5.8e-289 ccs S the current gene model (or a revised gene model) may contain a frame shift
EONCEDMH_01743 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
EONCEDMH_01744 7.5e-14
EONCEDMH_01745 1.2e-85 XK27_10930 K acetyltransferase
EONCEDMH_01746 1e-113 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EONCEDMH_01747 1.3e-120 yaaA S Belongs to the UPF0246 family
EONCEDMH_01748 9.3e-167 XK27_01785 S cog cog1284
EONCEDMH_01749 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
EONCEDMH_01751 1.2e-238 hisS 6.1.1.21 J histidyl-tRNA synthetase
EONCEDMH_01752 3.1e-89 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
EONCEDMH_01753 7.1e-42 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
EONCEDMH_01754 4.7e-08 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
EONCEDMH_01755 4.3e-219 metE 2.1.1.14 E Methionine synthase
EONCEDMH_01756 3.4e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
EONCEDMH_01757 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
EONCEDMH_01762 7e-115 nudL L hydrolase
EONCEDMH_01763 6.3e-54 K transcriptional regulator, PadR family
EONCEDMH_01764 8.6e-62 XK27_06920 S Protein of unknown function (DUF1700)
EONCEDMH_01765 1.8e-105 S Putative adhesin
EONCEDMH_01766 7.3e-160 XK27_06930 V domain protein
EONCEDMH_01767 1.6e-94 XK27_06935 K transcriptional regulator
EONCEDMH_01768 3.8e-52 ypaA M Membrane
EONCEDMH_01769 1.1e-10
EONCEDMH_01770 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EONCEDMH_01771 1.8e-47 veg S Biofilm formation stimulator VEG
EONCEDMH_01772 6.5e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
EONCEDMH_01773 2.2e-73 rplI J binds to the 23S rRNA
EONCEDMH_01774 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
EONCEDMH_01775 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
EONCEDMH_01776 7.8e-98 yvbG U UPF0056 membrane protein
EONCEDMH_01777 1.2e-218 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EONCEDMH_01778 2.3e-304 S Bacterial membrane protein, YfhO
EONCEDMH_01779 9.3e-63 isaA GH23 M Immunodominant staphylococcal antigen A
EONCEDMH_01780 5.9e-71 lytE M LysM domain protein
EONCEDMH_01781 4.4e-133 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EONCEDMH_01782 1.2e-149 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EONCEDMH_01783 3.5e-149 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EONCEDMH_01784 2.6e-89 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EONCEDMH_01785 1e-127 S sequence-specific DNA binding
EONCEDMH_01786 9.2e-234 ymfH S Peptidase M16
EONCEDMH_01787 2.5e-228 ymfF S Peptidase M16
EONCEDMH_01788 1.9e-57 yaaA S S4 domain protein YaaA
EONCEDMH_01789 3.7e-199 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EONCEDMH_01790 1.1e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
EONCEDMH_01791 7.2e-189 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
EONCEDMH_01792 9.3e-153 yvjA S membrane
EONCEDMH_01793 1.1e-305 ybiT S abc transporter atp-binding protein
EONCEDMH_01794 0.0 XK27_10405 S Bacterial membrane protein YfhO
EONCEDMH_01798 2.2e-117 yoaK S Protein of unknown function (DUF1275)
EONCEDMH_01799 2e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EONCEDMH_01800 1.5e-201 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
EONCEDMH_01801 3.2e-133 parB K Belongs to the ParB family
EONCEDMH_01802 8.5e-254 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EONCEDMH_01803 8e-197 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EONCEDMH_01804 3.2e-29 yyzM S Protein conserved in bacteria
EONCEDMH_01805 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EONCEDMH_01806 5.2e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EONCEDMH_01807 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EONCEDMH_01808 2.2e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
EONCEDMH_01809 8.7e-60 divIC D Septum formation initiator
EONCEDMH_01811 2.3e-232 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
EONCEDMH_01812 1.3e-227 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EONCEDMH_01813 2.9e-96 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
EONCEDMH_01814 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EONCEDMH_01815 0.0 3.5.1.28 NU amidase activity
EONCEDMH_01816 0.0 lpdA 1.8.1.4 C Dehydrogenase
EONCEDMH_01817 1.1e-211 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EONCEDMH_01818 1.4e-181 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EONCEDMH_01819 4.3e-183 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
EONCEDMH_01820 2e-201 hpk9 2.7.13.3 T protein histidine kinase activity
EONCEDMH_01821 1.2e-225 2.7.13.3 T protein histidine kinase activity
EONCEDMH_01822 0.0 S the current gene model (or a revised gene model) may contain a frame shift
EONCEDMH_01823 8.2e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EONCEDMH_01824 4.1e-121 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EONCEDMH_01825 1.1e-212 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EONCEDMH_01826 1.2e-244 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
EONCEDMH_01827 6.5e-182 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
EONCEDMH_01828 5.3e-153 rssA S Phospholipase, patatin family
EONCEDMH_01829 2e-101 estA E Lysophospholipase L1 and related esterases
EONCEDMH_01830 4e-279 S unusual protein kinase
EONCEDMH_01831 4.1e-38 S granule-associated protein
EONCEDMH_01832 9.8e-285 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EONCEDMH_01833 1.8e-196 S hmm pf01594
EONCEDMH_01834 2.8e-108 G Belongs to the phosphoglycerate mutase family
EONCEDMH_01835 5.4e-107 G Belongs to the phosphoglycerate mutase family
EONCEDMH_01836 1.4e-107 pgm G Belongs to the phosphoglycerate mutase family
EONCEDMH_01837 4.8e-143 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
EONCEDMH_01839 5e-185 wbbI M transferase activity, transferring glycosyl groups
EONCEDMH_01840 3.1e-173 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
EONCEDMH_01841 4.8e-215 glf 5.4.99.9 M UDP-galactopyranose mutase
EONCEDMH_01842 1.1e-157 S Acyltransferase family
EONCEDMH_01843 2e-250 epsU S Polysaccharide biosynthesis protein
EONCEDMH_01844 1.3e-173
EONCEDMH_01845 2.8e-153 M Glycosyltransferase like family 2
EONCEDMH_01846 1.7e-163 M Glycosyltransferase, group 2 family protein
EONCEDMH_01847 6.8e-121 Z012_10770 M Domain of unknown function (DUF1919)
EONCEDMH_01848 4.2e-214 wcoF M Glycosyltransferase, group 1 family protein
EONCEDMH_01849 8.2e-221 rgpAc GT4 M group 1 family protein
EONCEDMH_01850 8e-252 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
EONCEDMH_01851 5.9e-116 cpsD D COG0489 ATPases involved in chromosome partitioning
EONCEDMH_01852 1.2e-110 cps4C M biosynthesis protein
EONCEDMH_01853 6.8e-133 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
EONCEDMH_01854 1.2e-250 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
EONCEDMH_01855 4.9e-128 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
EONCEDMH_01856 8.7e-133 yfeJ 6.3.5.2 F glutamine amidotransferase
EONCEDMH_01857 5.2e-173 clcA_2 P Chloride transporter, ClC family
EONCEDMH_01858 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EONCEDMH_01859 4.2e-87 S Protein of unknown function (DUF1697)
EONCEDMH_01860 2.3e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
EONCEDMH_01861 4.7e-120 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EONCEDMH_01862 3.6e-252 V Glucan-binding protein C
EONCEDMH_01863 3.8e-227 V Glucan-binding protein C
EONCEDMH_01864 3.3e-106 ung2 3.2.2.27 L Uracil-DNA glycosylase
EONCEDMH_01865 2.5e-269 pepV 3.5.1.18 E Dipeptidase
EONCEDMH_01866 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
EONCEDMH_01867 1.6e-91 yybC
EONCEDMH_01868 1.5e-77 XK27_03610 K Gnat family
EONCEDMH_01869 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EONCEDMH_01870 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
EONCEDMH_01871 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EONCEDMH_01872 4.3e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
EONCEDMH_01873 5.5e-17 M LysM domain
EONCEDMH_01874 9.6e-86 ebsA S Family of unknown function (DUF5322)
EONCEDMH_01875 3.2e-228 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
EONCEDMH_01876 1.7e-35 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
EONCEDMH_01877 3.7e-79 hmpT S cog cog4720
EONCEDMH_01878 1.2e-135 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
EONCEDMH_01879 3.8e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EONCEDMH_01880 8e-189 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EONCEDMH_01882 1.8e-307 dnaK O Heat shock 70 kDa protein
EONCEDMH_01883 5.7e-73 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EONCEDMH_01884 9.2e-184 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EONCEDMH_01885 1.7e-97 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
EONCEDMH_01886 1.7e-140 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
EONCEDMH_01887 2.6e-129 ais G Phosphoglycerate mutase
EONCEDMH_01888 9.6e-242 XK27_08635 S UPF0210 protein
EONCEDMH_01889 2.3e-38 gcvR T UPF0237 protein
EONCEDMH_01890 3.3e-233 capA M Bacterial capsule synthesis protein
EONCEDMH_01891 8.6e-148 srtB 3.4.22.70 S Sortase family
EONCEDMH_01893 1.5e-29 K Helix-turn-helix domain
EONCEDMH_01894 1.3e-17
EONCEDMH_01895 1.5e-15 S Protein of unknown function (DUF1211)
EONCEDMH_01897 9e-52 frnE Q DSBA-like thioredoxin domain
EONCEDMH_01899 1.3e-123 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EONCEDMH_01900 1.7e-16 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EONCEDMH_01901 5.5e-47 trxA O Belongs to the thioredoxin family
EONCEDMH_01903 2.2e-98 M1-798 K Rhodanese Homology Domain
EONCEDMH_01904 1.2e-27 int2 L Belongs to the 'phage' integrase family
EONCEDMH_01905 1.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
EONCEDMH_01906 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EONCEDMH_01907 5.1e-22 K Transcriptional
EONCEDMH_01909 1.2e-149 degV S DegV family
EONCEDMH_01910 6e-91 yacP S RNA-binding protein containing a PIN domain
EONCEDMH_01911 1.1e-133 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EONCEDMH_01913 1.2e-65 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EONCEDMH_01914 9e-256 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
EONCEDMH_01915 2.5e-112 cysE 2.3.1.30 E serine acetyltransferase
EONCEDMH_01916 1.5e-138 S SseB protein N-terminal domain
EONCEDMH_01917 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
EONCEDMH_01918 6.9e-226 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EONCEDMH_01919 7.9e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EONCEDMH_01920 0.0 clpC O Belongs to the ClpA ClpB family
EONCEDMH_01921 1.8e-75 ctsR K Belongs to the CtsR family
EONCEDMH_01922 1.6e-82 S Putative small multi-drug export protein
EONCEDMH_01923 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EONCEDMH_01924 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
EONCEDMH_01925 4.2e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
EONCEDMH_01926 8.6e-287 ahpF O alkyl hydroperoxide reductase
EONCEDMH_01928 4.7e-94 S reductase
EONCEDMH_01929 3.9e-72 badR K Transcriptional regulator, marr family
EONCEDMH_01930 1.2e-35 XK27_02060 S Transglycosylase associated protein
EONCEDMH_01931 1.1e-236 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
EONCEDMH_01932 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EONCEDMH_01937 1.9e-07
EONCEDMH_01940 2.6e-10
EONCEDMH_01943 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
EONCEDMH_01944 6.8e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EONCEDMH_01945 6.5e-224 cinA 3.5.1.42 S Belongs to the CinA family
EONCEDMH_01946 2.5e-103 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
EONCEDMH_01947 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EONCEDMH_01949 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EONCEDMH_01951 2.4e-69 K LytTr DNA-binding domain
EONCEDMH_01952 6.7e-78 S Protein of unknown function (DUF3021)
EONCEDMH_01953 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EONCEDMH_01954 2.4e-54 ymcA 3.6.3.21 S Belongs to the UPF0342 family
EONCEDMH_01955 3.4e-68 argR K Regulates arginine biosynthesis genes
EONCEDMH_01956 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
EONCEDMH_01957 2.8e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EONCEDMH_01958 5.6e-33
EONCEDMH_01959 3.6e-174 1.1.1.169 H Ketopantoate reductase
EONCEDMH_01960 5.1e-201 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EONCEDMH_01961 2.2e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EONCEDMH_01962 6.1e-238 purD 6.3.4.13 F Belongs to the GARS family
EONCEDMH_01963 5e-156 S CHAP domain
EONCEDMH_01964 7.3e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
EONCEDMH_01965 1.3e-99 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EONCEDMH_01966 2.5e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
EONCEDMH_01967 4.6e-274 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EONCEDMH_01968 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EONCEDMH_01969 1.3e-128 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
EONCEDMH_01970 4.8e-30 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
EONCEDMH_01971 3.5e-183 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EONCEDMH_01972 1.3e-137 recO L Involved in DNA repair and RecF pathway recombination
EONCEDMH_01973 1.8e-215 araT 2.6.1.1 E Aminotransferase
EONCEDMH_01974 2.8e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EONCEDMH_01975 7.9e-83 usp 3.5.1.28 CBM50 S CHAP domain
EONCEDMH_01976 3.9e-82 mreD M rod shape-determining protein MreD
EONCEDMH_01977 1.2e-109 mreC M Involved in formation and maintenance of cell shape
EONCEDMH_01983 2.6e-10
EONCEDMH_01991 0.0 M domain protein
EONCEDMH_01992 0.0 zmpB M signal peptide protein, YSIRK family
EONCEDMH_01993 0.0 GM domain, Protein
EONCEDMH_01994 1.3e-218 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
EONCEDMH_01995 0.0 sbcC L ATPase involved in DNA repair
EONCEDMH_01996 0.0 M family 8
EONCEDMH_01997 6.1e-211 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
EONCEDMH_01998 2.9e-290 asp1 S Accessory Sec system protein Asp1
EONCEDMH_01999 8.3e-290 asp2 3.4.11.5 S Accessory Sec system protein Asp2
EONCEDMH_02000 1.7e-78 asp3 S Accessory Sec system protein Asp3
EONCEDMH_02001 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EONCEDMH_02002 1.5e-280 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
EONCEDMH_02003 2e-242 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
EONCEDMH_02004 2.6e-17 S Accessory secretory protein Sec Asp4
EONCEDMH_02005 3.6e-16 S Accessory secretory protein Sec, Asp5
EONCEDMH_02006 4e-184 nss M transferase activity, transferring glycosyl groups
EONCEDMH_02007 0.0 sraP UW Hep Hag repeat protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)