ORF_ID e_value Gene_name EC_number CAZy COGs Description
MBCFHEDH_00001 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
MBCFHEDH_00002 6.8e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MBCFHEDH_00003 6.5e-224 cinA 3.5.1.42 S Belongs to the CinA family
MBCFHEDH_00004 2.5e-103 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
MBCFHEDH_00005 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MBCFHEDH_00007 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MBCFHEDH_00009 2.4e-69 K LytTr DNA-binding domain
MBCFHEDH_00010 6.7e-78 S Protein of unknown function (DUF3021)
MBCFHEDH_00011 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MBCFHEDH_00012 2.4e-54 ymcA 3.6.3.21 S Belongs to the UPF0342 family
MBCFHEDH_00013 3.4e-68 argR K Regulates arginine biosynthesis genes
MBCFHEDH_00014 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
MBCFHEDH_00015 2.8e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MBCFHEDH_00016 5.6e-33
MBCFHEDH_00017 3.6e-174 1.1.1.169 H Ketopantoate reductase
MBCFHEDH_00018 5.1e-201 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MBCFHEDH_00019 2.2e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MBCFHEDH_00020 6.1e-238 purD 6.3.4.13 F Belongs to the GARS family
MBCFHEDH_00021 5e-156 S CHAP domain
MBCFHEDH_00022 7.3e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MBCFHEDH_00023 1.3e-99 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MBCFHEDH_00024 2.5e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MBCFHEDH_00025 4.6e-274 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MBCFHEDH_00026 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MBCFHEDH_00027 1.3e-128 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MBCFHEDH_00028 4.8e-30 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MBCFHEDH_00029 3.5e-183 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MBCFHEDH_00030 1.3e-137 recO L Involved in DNA repair and RecF pathway recombination
MBCFHEDH_00031 1.8e-215 araT 2.6.1.1 E Aminotransferase
MBCFHEDH_00032 2.8e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MBCFHEDH_00033 7.9e-83 usp 3.5.1.28 CBM50 S CHAP domain
MBCFHEDH_00034 3.9e-82 mreD M rod shape-determining protein MreD
MBCFHEDH_00035 1.2e-109 mreC M Involved in formation and maintenance of cell shape
MBCFHEDH_00041 2.6e-10
MBCFHEDH_00049 1.9e-153 endA F DNA RNA non-specific endonuclease
MBCFHEDH_00050 7.2e-26 epuA S DNA-directed RNA polymerase subunit beta
MBCFHEDH_00051 2.1e-230 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MBCFHEDH_00053 2.5e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MBCFHEDH_00054 7e-134 G Domain of unknown function (DUF4832)
MBCFHEDH_00055 2.7e-83 S membrane
MBCFHEDH_00056 5.1e-96 P VTC domain
MBCFHEDH_00057 1e-222 cotH M CotH kinase protein
MBCFHEDH_00058 4.4e-184 pelG M Putative exopolysaccharide Exporter (EPS-E)
MBCFHEDH_00059 1.1e-272 pelF GT4 M Domain of unknown function (DUF3492)
MBCFHEDH_00060 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
MBCFHEDH_00061 2.7e-147
MBCFHEDH_00062 2.1e-276 5.1.3.2 GM Psort location CytoplasmicMembrane, score
MBCFHEDH_00063 1e-210 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MBCFHEDH_00064 1.1e-170 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MBCFHEDH_00065 1.7e-301 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MBCFHEDH_00066 3.7e-85 ytsP 1.8.4.14 T GAF domain-containing protein
MBCFHEDH_00067 1.5e-158 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MBCFHEDH_00068 3.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
MBCFHEDH_00071 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MBCFHEDH_00072 2.3e-213 XK27_05110 P Chloride transporter ClC family
MBCFHEDH_00073 1.2e-37 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
MBCFHEDH_00074 3.2e-281 clcA P Chloride transporter, ClC family
MBCFHEDH_00075 1e-75 fld C Flavodoxin
MBCFHEDH_00076 3.4e-19 XK27_08880
MBCFHEDH_00077 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
MBCFHEDH_00078 9.5e-149 estA CE1 S Esterase
MBCFHEDH_00079 1.5e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MBCFHEDH_00080 8.9e-136 XK27_08845 S abc transporter atp-binding protein
MBCFHEDH_00081 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
MBCFHEDH_00082 2.4e-176 XK27_08835 S ABC transporter substrate binding protein
MBCFHEDH_00083 1.7e-18 S Domain of unknown function (DUF4649)
MBCFHEDH_00084 0.0 htaA 3.4.21.72 Q the current gene model (or a revised gene model) may contain a frame shift
MBCFHEDH_00088 2.7e-23
MBCFHEDH_00089 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
MBCFHEDH_00090 0.0 3.5.1.28 M domain protein
MBCFHEDH_00091 2.9e-88 V abc transporter atp-binding protein
MBCFHEDH_00092 2.4e-14
MBCFHEDH_00094 2.3e-74 K Transcriptional regulatory protein, C terminal
MBCFHEDH_00095 1.2e-64 2.7.13.3 T Histidine kinase
MBCFHEDH_00096 1.5e-90 maa 2.3.1.79 GK Maltose O-acetyltransferase
MBCFHEDH_00097 9.3e-63 rmaI K Transcriptional regulator, MarR family
MBCFHEDH_00098 7.2e-218 EGP Major facilitator Superfamily
MBCFHEDH_00099 4.6e-108 XK27_00785 S CAAX protease self-immunity
MBCFHEDH_00100 5.1e-119 mleR K malolactic fermentation system
MBCFHEDH_00101 4.7e-47 K Helix-turn-helix
MBCFHEDH_00102 4.5e-311 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme, NAD binding domain
MBCFHEDH_00103 1.4e-159 mleP S Sodium Bile acid symporter family
MBCFHEDH_00104 1.9e-91 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MBCFHEDH_00106 1.1e-219 S dextransucrase activity
MBCFHEDH_00107 0.0 S dextransucrase activity
MBCFHEDH_00108 6.4e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MBCFHEDH_00109 8.1e-233 vicK 2.7.13.3 T Histidine kinase
MBCFHEDH_00110 1e-153 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
MBCFHEDH_00111 1.5e-56 S Protein of unknown function (DUF454)
MBCFHEDH_00112 6.7e-226 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
MBCFHEDH_00113 7.8e-146 yidA S hydrolases of the HAD superfamily
MBCFHEDH_00114 1.4e-137 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
MBCFHEDH_00115 5.1e-131 XK27_00120 2.4.2.3 F Phosphorylase superfamily
MBCFHEDH_00116 1.2e-67 ywiB S Domain of unknown function (DUF1934)
MBCFHEDH_00117 0.0 pacL 3.6.3.8 P cation transport ATPase
MBCFHEDH_00118 3.6e-129 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
MBCFHEDH_00119 1.8e-153 yjjH S Calcineurin-like phosphoesterase
MBCFHEDH_00120 3.5e-205 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MBCFHEDH_00121 2.1e-182 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MBCFHEDH_00122 3.2e-124 ftsE D cell division ATP-binding protein FtsE
MBCFHEDH_00123 7.3e-164 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MBCFHEDH_00124 6.6e-92 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
MBCFHEDH_00125 1.2e-176 yubA S permease
MBCFHEDH_00126 8.5e-221 G COG0457 FOG TPR repeat
MBCFHEDH_00127 2.5e-95 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MBCFHEDH_00128 1.4e-147 bmgA U Relaxase mobilization nuclease domain protein
MBCFHEDH_00129 3.9e-78
MBCFHEDH_00130 2.7e-35
MBCFHEDH_00131 5.3e-200 L Psort location Cytoplasmic, score 8.96
MBCFHEDH_00132 1.1e-37
MBCFHEDH_00133 3.7e-47 S Psort location Cytoplasmic, score 8.96
MBCFHEDH_00134 1.6e-31 S Psort location Cytoplasmic, score 8.96
MBCFHEDH_00135 3.7e-88 bmgA U Relaxase mobilization nuclease domain protein
MBCFHEDH_00136 2.9e-73
MBCFHEDH_00137 2.9e-119
MBCFHEDH_00138 2.1e-185 L Psort location Cytoplasmic, score 8.96
MBCFHEDH_00139 1.9e-76 S Psort location Cytoplasmic, score 8.96
MBCFHEDH_00140 2.6e-33
MBCFHEDH_00141 1.3e-38 DJ Psort location Cytoplasmic, score
MBCFHEDH_00142 3.3e-09 sraP UW domain, Protein
MBCFHEDH_00143 6.1e-175 S dextransucrase activity
MBCFHEDH_00144 1.4e-104 S Psort location Cytoplasmic, score 8.96
MBCFHEDH_00146 6.4e-35 lytC 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
MBCFHEDH_00147 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
MBCFHEDH_00148 1.7e-146 ycdO P periplasmic lipoprotein involved in iron transport
MBCFHEDH_00149 2.2e-229 ycdB P peroxidase
MBCFHEDH_00150 3.1e-290 ywbL P COG0672 High-affinity Fe2 Pb2 permease
MBCFHEDH_00151 2.2e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MBCFHEDH_00152 1.9e-23 tatA U protein secretion
MBCFHEDH_00153 1.8e-212 msmX P Belongs to the ABC transporter superfamily
MBCFHEDH_00154 2.2e-151 malG P ABC transporter (Permease
MBCFHEDH_00155 8.2e-249 malF P ABC transporter (Permease
MBCFHEDH_00156 3.9e-229 malX G ABC transporter
MBCFHEDH_00157 1.7e-171 malR K Transcriptional regulator
MBCFHEDH_00158 2.8e-298 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
MBCFHEDH_00159 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MBCFHEDH_00160 5.2e-39
MBCFHEDH_00161 6.1e-185 lplA 6.3.1.20 H Lipoate-protein ligase
MBCFHEDH_00162 6.2e-191 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
MBCFHEDH_00163 0.0 pepN 3.4.11.2 E aminopeptidase
MBCFHEDH_00164 1.2e-112 phoU P Plays a role in the regulation of phosphate uptake
MBCFHEDH_00165 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MBCFHEDH_00166 1.7e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MBCFHEDH_00167 9.1e-156 pstA P phosphate transport system permease
MBCFHEDH_00168 4.7e-155 pstC P probably responsible for the translocation of the substrate across the membrane
MBCFHEDH_00169 2.6e-155 pstS P phosphate
MBCFHEDH_00170 5.3e-245 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
MBCFHEDH_00171 2.1e-140 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
MBCFHEDH_00172 6.7e-44 yktA S Belongs to the UPF0223 family
MBCFHEDH_00173 7.9e-70 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MBCFHEDH_00174 7.4e-169 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MBCFHEDH_00175 2.1e-146 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MBCFHEDH_00176 1.5e-234 XK27_04775 S hemerythrin HHE cation binding domain
MBCFHEDH_00177 8e-35 M1-755 P Hemerythrin HHE cation binding domain protein
MBCFHEDH_00178 4e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
MBCFHEDH_00179 4.2e-86 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MBCFHEDH_00180 4.7e-137 S haloacid dehalogenase-like hydrolase
MBCFHEDH_00181 5.6e-239 metY 2.5.1.49 E o-acetylhomoserine
MBCFHEDH_00182 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MBCFHEDH_00183 4.2e-237 agcS E (Alanine) symporter
MBCFHEDH_00184 8.9e-243 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MBCFHEDH_00185 7.1e-170 bglC K Transcriptional regulator
MBCFHEDH_00186 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
MBCFHEDH_00187 9.3e-81 yecS P ABC transporter (Permease
MBCFHEDH_00188 6e-149 yckB ET Belongs to the bacterial solute-binding protein 3 family
MBCFHEDH_00189 1.4e-230 nylA 3.5.1.4 J Belongs to the amidase family
MBCFHEDH_00190 1.7e-111 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MBCFHEDH_00191 5e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MBCFHEDH_00192 5.5e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MBCFHEDH_00193 3.8e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MBCFHEDH_00194 6.8e-93 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
MBCFHEDH_00195 8.8e-134 S TraX protein
MBCFHEDH_00196 6.2e-307 FbpA K RNA-binding protein homologous to eukaryotic snRNP
MBCFHEDH_00197 4e-276 S Psort location CytoplasmicMembrane, score
MBCFHEDH_00198 3.1e-232 dinF V Mate efflux family protein
MBCFHEDH_00199 1.1e-173 yclQ P ABC-type enterochelin transport system, periplasmic component
MBCFHEDH_00200 0.0 V Type III restriction enzyme, res subunit
MBCFHEDH_00201 5.4e-110 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
MBCFHEDH_00202 3e-139 2.4.2.3 F Phosphorylase superfamily
MBCFHEDH_00203 1.5e-109 K Bacterial regulatory proteins, tetR family
MBCFHEDH_00204 8.7e-177 ybhR V ABC-2 family transporter protein
MBCFHEDH_00205 1e-125 ybhF_2 V abc transporter atp-binding protein
MBCFHEDH_00206 3.5e-144 G protein with an alpha beta hydrolase fold
MBCFHEDH_00207 2.5e-122 spxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MBCFHEDH_00208 0.0 copA 3.6.3.54 P P-type ATPase
MBCFHEDH_00209 1.2e-64 silP 1.9.3.1, 3.6.3.54 S cog cog4633
MBCFHEDH_00210 6.2e-64 copY K Copper transport repressor, CopY TcrY family
MBCFHEDH_00211 2.3e-187 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
MBCFHEDH_00212 2.2e-188 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
MBCFHEDH_00213 1.5e-153 czcD P cation diffusion facilitator family transporter
MBCFHEDH_00214 3.5e-94 K Transcriptional regulator, TetR family
MBCFHEDH_00215 3.6e-58 S Protein of unknown function with HXXEE motif
MBCFHEDH_00216 4.9e-38
MBCFHEDH_00217 1.1e-148 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MBCFHEDH_00218 2.2e-151 I Alpha/beta hydrolase family
MBCFHEDH_00219 3e-177 1.1.1.1 C nadph quinone reductase
MBCFHEDH_00220 3.8e-67 K Transcriptional regulator
MBCFHEDH_00221 1.9e-62 pnuC H nicotinamide mononucleotide transporter
MBCFHEDH_00222 1.8e-150 cbiO2 P ABC transporter, ATP-binding protein
MBCFHEDH_00223 1e-156 P ATPase activity
MBCFHEDH_00224 1.1e-131 cbiQ P cobalt transport
MBCFHEDH_00225 6.3e-92 2.7.7.65 T Psort location CytoplasmicMembrane, score
MBCFHEDH_00226 2.4e-139 S Phenazine biosynthesis protein
MBCFHEDH_00227 2e-259 proWX P ABC transporter
MBCFHEDH_00228 5e-128 proV E abc transporter atp-binding protein
MBCFHEDH_00229 4e-145 1.6.5.2 GM NmrA family
MBCFHEDH_00230 2.3e-67 mgrA K Transcriptional regulator, MarR family
MBCFHEDH_00231 3.1e-130 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
MBCFHEDH_00232 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MBCFHEDH_00235 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MBCFHEDH_00237 4e-136 IQ Acetoin reductase
MBCFHEDH_00238 1e-42 pspE P Rhodanese-like protein
MBCFHEDH_00239 5.5e-71 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MBCFHEDH_00240 4.7e-221 XK27_05470 E Methionine synthase
MBCFHEDH_00241 6.2e-257 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MBCFHEDH_00242 3.2e-221 T PhoQ Sensor
MBCFHEDH_00243 5.1e-119 KT Transcriptional regulatory protein, C terminal
MBCFHEDH_00244 2.1e-146 S TraX protein
MBCFHEDH_00246 2.6e-52 V ABC-2 family transporter protein
MBCFHEDH_00247 2.1e-83 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
MBCFHEDH_00248 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MBCFHEDH_00249 4.6e-157 dprA LU DNA protecting protein DprA
MBCFHEDH_00250 1.2e-152 GK ROK family
MBCFHEDH_00251 3.5e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MBCFHEDH_00252 9.4e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MBCFHEDH_00253 2.4e-127 K DNA-binding helix-turn-helix protein
MBCFHEDH_00254 6e-83 niaR S small molecule binding protein (contains 3H domain)
MBCFHEDH_00255 2.1e-83
MBCFHEDH_00256 1.6e-272 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MBCFHEDH_00257 4.9e-54 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MBCFHEDH_00258 7.7e-126 gntR1 K transcriptional
MBCFHEDH_00259 2.3e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MBCFHEDH_00260 6.7e-99 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MBCFHEDH_00261 4.2e-189 adhP 1.1.1.1 C alcohol dehydrogenase
MBCFHEDH_00262 1.8e-44
MBCFHEDH_00263 2.9e-50
MBCFHEDH_00264 6.7e-270 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MBCFHEDH_00265 9.7e-155 aatB ET ABC transporter substrate-binding protein
MBCFHEDH_00266 1.4e-110 glnQ 3.6.3.21 E abc transporter atp-binding protein
MBCFHEDH_00267 3.1e-105 artQ P ABC transporter (Permease
MBCFHEDH_00268 6.6e-59 phnA P Alkylphosphonate utilization operon protein PhnA
MBCFHEDH_00269 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MBCFHEDH_00270 2.2e-165 cpsY K Transcriptional regulator
MBCFHEDH_00271 9.3e-127 mur1 3.4.17.14, 3.5.1.28 NU muramidase
MBCFHEDH_00272 2.4e-168 yeiH S Membrane
MBCFHEDH_00274 3.4e-09
MBCFHEDH_00275 1.4e-289 adcA P Belongs to the bacterial solute-binding protein 9 family
MBCFHEDH_00276 4.8e-143 XK27_10720 D peptidase activity
MBCFHEDH_00277 2.2e-273 pepD E Dipeptidase
MBCFHEDH_00278 5.7e-161 whiA K May be required for sporulation
MBCFHEDH_00279 1.4e-181 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MBCFHEDH_00280 8.5e-162 rapZ S Displays ATPase and GTPase activities
MBCFHEDH_00281 1.9e-133 yejC S cyclic nucleotide-binding protein
MBCFHEDH_00282 9.2e-198 D nuclear chromosome segregation
MBCFHEDH_00283 1.4e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
MBCFHEDH_00284 4.6e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MBCFHEDH_00285 8.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
MBCFHEDH_00286 2.6e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MBCFHEDH_00287 2.3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
MBCFHEDH_00288 2.4e-199 pmrB EGP Major facilitator Superfamily
MBCFHEDH_00289 1.4e-18
MBCFHEDH_00290 5.4e-261 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
MBCFHEDH_00291 1.4e-212 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
MBCFHEDH_00292 6.6e-76 ypmB S Protein conserved in bacteria
MBCFHEDH_00293 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MBCFHEDH_00294 8.9e-113 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
MBCFHEDH_00295 5e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
MBCFHEDH_00296 2.3e-177 yufP S Belongs to the binding-protein-dependent transport system permease family
MBCFHEDH_00297 3.5e-280 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
MBCFHEDH_00298 1.8e-190 tcsA S membrane
MBCFHEDH_00299 9.1e-63 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MBCFHEDH_00300 7.9e-112 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MBCFHEDH_00301 1.7e-227 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
MBCFHEDH_00302 3.5e-103 rsmC 2.1.1.172 J Methyltransferase small domain protein
MBCFHEDH_00303 2.6e-169 coaA 2.7.1.33 F Pantothenic acid kinase
MBCFHEDH_00304 2.3e-29 rpsT J Binds directly to 16S ribosomal RNA
MBCFHEDH_00305 3.8e-233 T PhoQ Sensor
MBCFHEDH_00306 2.1e-120 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MBCFHEDH_00307 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
MBCFHEDH_00308 3.1e-111 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
MBCFHEDH_00309 2.4e-90 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MBCFHEDH_00310 2.7e-92 panT S ECF transporter, substrate-specific component
MBCFHEDH_00311 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
MBCFHEDH_00312 2.4e-164 metF 1.5.1.20 E reductase
MBCFHEDH_00313 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MBCFHEDH_00315 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
MBCFHEDH_00316 9.4e-113 apt 2.4.2.22, 2.4.2.7 F TRSP domain C terminus to PRTase_2
MBCFHEDH_00317 3.4e-144 stiP J Phosphoribosyl transferase (PRTase)
MBCFHEDH_00318 3.1e-199 yceG S Putative component of 'biosynthetic module'
MBCFHEDH_00319 9.5e-166 yceH P Belongs to the TelA family
MBCFHEDH_00320 1.2e-90 T proteins involved in stress response, homologs of TerZ and
MBCFHEDH_00321 2e-76 T proteins involved in stress response, homologs of TerZ and
MBCFHEDH_00322 1.8e-89 T proteins involved in stress response, homologs of TerZ and
MBCFHEDH_00323 0.0 3.6.3.8 P cation transport ATPase
MBCFHEDH_00324 1.5e-74 3.1.3.12 S hydrolases of the HAD superfamily
MBCFHEDH_00325 1.4e-91 G Citrate lyase beta subunit
MBCFHEDH_00326 6.3e-235 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MBCFHEDH_00327 8.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MBCFHEDH_00328 3.6e-235 dltB M Membrane protein involved in D-alanine export
MBCFHEDH_00329 9.3e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MBCFHEDH_00330 0.0 XK27_10035 V abc transporter atp-binding protein
MBCFHEDH_00331 4.2e-290 yfiB1 V abc transporter atp-binding protein
MBCFHEDH_00332 6.4e-100 pvaA M lytic transglycosylase activity
MBCFHEDH_00333 8.4e-179 ndpA S 37-kD nucleoid-associated bacterial protein
MBCFHEDH_00334 2.3e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MBCFHEDH_00335 8.8e-102 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MBCFHEDH_00336 2.2e-143 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MBCFHEDH_00337 2.4e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MBCFHEDH_00338 7.8e-111 tdk 2.7.1.21 F thymidine kinase
MBCFHEDH_00339 1.9e-181 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MBCFHEDH_00340 1.3e-150 gst O Glutathione S-transferase
MBCFHEDH_00341 9.3e-175 nrnA 3.1.13.3, 3.1.3.7 S domain protein
MBCFHEDH_00342 6.8e-170 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MBCFHEDH_00343 4.4e-45 rpmE2 J 50S ribosomal protein L31
MBCFHEDH_00344 5.7e-228 mntH P Mn2 and Fe2 transporters of the NRAMP family
MBCFHEDH_00345 1.2e-161 ypuA S secreted protein
MBCFHEDH_00346 8.2e-72 yaeR E COG0346 Lactoylglutathione lyase and related lyases
MBCFHEDH_00347 7.9e-132 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
MBCFHEDH_00348 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MBCFHEDH_00349 4.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MBCFHEDH_00350 3.9e-254 noxE P NADH oxidase
MBCFHEDH_00351 1.1e-294 yfmM S abc transporter atp-binding protein
MBCFHEDH_00352 1.1e-79 XK27_01265 S ECF-type riboflavin transporter, S component
MBCFHEDH_00353 1.6e-141 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
MBCFHEDH_00354 1.6e-83 S ECF-type riboflavin transporter, S component
MBCFHEDH_00356 2.2e-235 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MBCFHEDH_00357 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
MBCFHEDH_00359 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MBCFHEDH_00360 5.4e-92 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MBCFHEDH_00361 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MBCFHEDH_00362 1e-22 WQ51_00220 K Helix-turn-helix domain
MBCFHEDH_00363 4e-77 S Protein of unknown function (DUF3278)
MBCFHEDH_00364 0.0 smc D Required for chromosome condensation and partitioning
MBCFHEDH_00365 9.3e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MBCFHEDH_00366 1.7e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MBCFHEDH_00367 3.6e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MBCFHEDH_00368 3.3e-118 alkD L DNA alkylation repair enzyme
MBCFHEDH_00369 5.7e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MBCFHEDH_00370 5.2e-87 pat 2.3.1.183 M acetyltransferase
MBCFHEDH_00371 4e-270 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MBCFHEDH_00372 2.6e-152 L PFAM Integrase catalytic region
MBCFHEDH_00373 7.4e-278 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
MBCFHEDH_00374 2.6e-36 P (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MBCFHEDH_00375 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MBCFHEDH_00376 3.2e-98 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
MBCFHEDH_00377 1.5e-18 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
MBCFHEDH_00378 3e-119 sdaAB 4.3.1.17 E L-serine dehydratase
MBCFHEDH_00379 5.8e-147 sdaAA 4.3.1.17 E L-serine dehydratase
MBCFHEDH_00380 2.1e-123 tktC 2.2.1.1 G Transketolase, pyrimidine binding domain
MBCFHEDH_00381 1.2e-123 tktN 2.2.1.1 G 1-deoxy-D-xylulose-5-phosphate synthase
MBCFHEDH_00382 2e-215 ulaA 2.7.1.194 S PTS system sugar-specific permease component
MBCFHEDH_00383 3.7e-42 ulaB 2.7.1.194 G COG3414 Phosphotransferase system galactitol-specific IIB component
MBCFHEDH_00384 1e-223 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MBCFHEDH_00385 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
MBCFHEDH_00386 1.8e-159 yjlA EG membrane
MBCFHEDH_00387 2.3e-82 3.4.21.89 S RDD family
MBCFHEDH_00388 5.7e-129 K sequence-specific DNA binding
MBCFHEDH_00389 6e-149 V ABC transporter, ATP-binding protein
MBCFHEDH_00390 9.5e-95 S ABC-2 family transporter protein
MBCFHEDH_00391 6e-142 K sequence-specific DNA binding
MBCFHEDH_00392 1.7e-48
MBCFHEDH_00393 1.3e-36 yfiQ K -acetyltransferase
MBCFHEDH_00394 1.1e-141 S ABC-2 family transporter protein
MBCFHEDH_00395 2.4e-142 S ABC-2 family transporter protein
MBCFHEDH_00396 1.2e-185 S abc transporter atp-binding protein
MBCFHEDH_00399 4.3e-85 yfjR K regulation of single-species biofilm formation
MBCFHEDH_00400 8.8e-125 S Protein of unknown function DUF262
MBCFHEDH_00401 1.2e-206 S Protein of unknown function DUF262
MBCFHEDH_00402 1.5e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MBCFHEDH_00403 2e-181 desK 2.7.13.3 T Histidine kinase
MBCFHEDH_00404 2e-132 yvfS V ABC-2 type transporter
MBCFHEDH_00405 6.7e-159 XK27_09825 V abc transporter atp-binding protein
MBCFHEDH_00408 5.1e-165 yocS S Transporter
MBCFHEDH_00409 2e-82 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
MBCFHEDH_00410 4e-21 P ABC transporter transmembrane region
MBCFHEDH_00411 3e-33 M translation initiation factor activity
MBCFHEDH_00413 1.2e-17
MBCFHEDH_00414 3.5e-43
MBCFHEDH_00415 3.5e-271 S Protein of unknown function (DUF2971)
MBCFHEDH_00416 4.1e-79 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MBCFHEDH_00417 1.9e-27 3.6.1.55 F NUDIX domain
MBCFHEDH_00418 3.6e-154
MBCFHEDH_00419 6.1e-25 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
MBCFHEDH_00420 2.2e-115 yvfS V Transporter
MBCFHEDH_00421 2.2e-154 XK27_09825 V abc transporter atp-binding protein
MBCFHEDH_00422 7e-15 liaI KT membrane
MBCFHEDH_00423 7.6e-30 liaI KT membrane
MBCFHEDH_00424 6.1e-93 XK27_05000 S metal cluster binding
MBCFHEDH_00425 0.0 V ABC transporter (permease)
MBCFHEDH_00426 1.6e-132 macB2 V ABC transporter, ATP-binding protein
MBCFHEDH_00427 4e-165 T Histidine kinase
MBCFHEDH_00428 5.4e-124 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MBCFHEDH_00429 6.7e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MBCFHEDH_00430 1.2e-222 pbuX F xanthine permease
MBCFHEDH_00431 5.7e-278 V (ABC) transporter
MBCFHEDH_00432 3.7e-143 K sequence-specific DNA binding
MBCFHEDH_00433 1.1e-242 norM V Multidrug efflux pump
MBCFHEDH_00435 1.2e-177 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MBCFHEDH_00436 1.6e-13
MBCFHEDH_00437 1.2e-31 T DNase/tRNase domain of colicin-like bacteriocin
MBCFHEDH_00438 0.0 S Domain of unknown function DUF87
MBCFHEDH_00439 1.2e-125 T ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MBCFHEDH_00440 9.2e-229 brnQ E Component of the transport system for branched-chain amino acids
MBCFHEDH_00441 8.7e-181 manA 5.3.1.8 G mannose-6-phosphate isomerase
MBCFHEDH_00442 3.2e-56 S Protein of unknown function (DUF3290)
MBCFHEDH_00443 1.7e-100 S Protein of unknown function (DUF421)
MBCFHEDH_00444 5.9e-15 csbD K CsbD-like
MBCFHEDH_00445 2.3e-28 S Carbohydrate-binding domain-containing protein Cthe_2159
MBCFHEDH_00446 1.5e-50 XK27_01300 P Protein conserved in bacteria
MBCFHEDH_00447 4.3e-213 yfnA E amino acid
MBCFHEDH_00448 0.0 S dextransucrase activity
MBCFHEDH_00449 2.1e-137 tcyC2 3.6.3.21 E abc transporter atp-binding protein
MBCFHEDH_00450 2.1e-112 yxeN P ABC transporter, permease protein
MBCFHEDH_00451 1.3e-109 ytmL P ABC transporter (Permease
MBCFHEDH_00452 1.8e-164 ET ABC transporter substrate-binding protein
MBCFHEDH_00453 1.4e-176 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
MBCFHEDH_00454 1e-84 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
MBCFHEDH_00455 2e-42 S Sugar efflux transporter for intercellular exchange
MBCFHEDH_00457 3.1e-14 XK27_10130
MBCFHEDH_00458 7.3e-206 P FtsX-like permease family
MBCFHEDH_00459 2.3e-122 V abc transporter atp-binding protein
MBCFHEDH_00460 5.3e-96 K WHG domain
MBCFHEDH_00461 7.2e-172 ydhF S Aldo keto reductase
MBCFHEDH_00462 6.7e-110 XK27_02070 S nitroreductase
MBCFHEDH_00463 3.2e-150 1.13.11.2 S glyoxalase
MBCFHEDH_00464 7.5e-74 ywnA K Transcriptional regulator
MBCFHEDH_00465 7e-153 E Alpha/beta hydrolase of unknown function (DUF915)
MBCFHEDH_00466 8.7e-224 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MBCFHEDH_00467 3.7e-168 bcrA V abc transporter atp-binding protein
MBCFHEDH_00468 8.1e-129 S ABC-2 family transporter protein
MBCFHEDH_00469 2.5e-45 S Domain of unknown function (DUF4352)
MBCFHEDH_00470 4e-148 T PhoQ Sensor
MBCFHEDH_00471 1.9e-124 T Xre family transcriptional regulator
MBCFHEDH_00472 1.7e-108 drgA C nitroreductase
MBCFHEDH_00473 1.1e-103 yoaK S Protein of unknown function (DUF1275)
MBCFHEDH_00474 1.3e-38 DJ nuclease activity
MBCFHEDH_00475 5.5e-30 XK27_10490
MBCFHEDH_00476 9.2e-158 yvgN C reductase
MBCFHEDH_00477 1.4e-209 S Tetratricopeptide repeat
MBCFHEDH_00478 0.0 lacL 3.2.1.23 G -beta-galactosidase
MBCFHEDH_00479 0.0 lacS G transporter
MBCFHEDH_00480 7.6e-202 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
MBCFHEDH_00481 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MBCFHEDH_00482 8.6e-284 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
MBCFHEDH_00483 1.1e-220 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MBCFHEDH_00484 2.6e-151 galR K Transcriptional regulator
MBCFHEDH_00485 2.4e-49 L COG1943 Transposase and inactivated derivatives
MBCFHEDH_00486 4.2e-308 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
MBCFHEDH_00487 7.2e-226 vncS 2.7.13.3 T Histidine kinase
MBCFHEDH_00488 1.5e-115 K Response regulator receiver domain protein
MBCFHEDH_00489 1.1e-232 vex3 V Efflux ABC transporter, permease protein
MBCFHEDH_00490 1.9e-107 vex2 V abc transporter atp-binding protein
MBCFHEDH_00491 1.7e-203 vex1 V Efflux ABC transporter, permease protein
MBCFHEDH_00492 1.1e-283 XK27_07020 S Belongs to the UPF0371 family
MBCFHEDH_00494 3.8e-196 gldA 1.1.1.6 C glycerol dehydrogenase
MBCFHEDH_00495 1.6e-177 XK27_10475 S oxidoreductase
MBCFHEDH_00496 1.4e-57 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
MBCFHEDH_00497 3.2e-93 dhaL 2.7.1.121 S Dihydroxyacetone kinase
MBCFHEDH_00498 1.4e-176 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
MBCFHEDH_00499 1.3e-227 thrE K Psort location CytoplasmicMembrane, score
MBCFHEDH_00500 0.0 M Putative cell wall binding repeat
MBCFHEDH_00501 6e-125 T Ser Thr phosphatase family protein
MBCFHEDH_00502 2.1e-33 S Immunity protein 41
MBCFHEDH_00503 0.0 pepO 3.4.24.71 O Peptidase family M13
MBCFHEDH_00504 4.5e-07 S Enterocin A Immunity
MBCFHEDH_00506 4.6e-15 S integral membrane protein
MBCFHEDH_00507 1.1e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
MBCFHEDH_00508 1.2e-113 yhfC S Putative membrane peptidase family (DUF2324)
MBCFHEDH_00509 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
MBCFHEDH_00511 1.2e-253 S dextransucrase activity
MBCFHEDH_00512 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
MBCFHEDH_00513 9.1e-36 M Putative cell wall binding repeat
MBCFHEDH_00514 5.2e-23 S dextransucrase activity
MBCFHEDH_00515 1.3e-236 M Putative cell wall binding repeat
MBCFHEDH_00516 2.2e-236 S dextransucrase activity
MBCFHEDH_00517 3.1e-92 S dextransucrase activity
MBCFHEDH_00518 3.7e-180 S dextransucrase activity
MBCFHEDH_00519 7.3e-101 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MBCFHEDH_00520 3.1e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MBCFHEDH_00521 0.0 M Putative cell wall binding repeat
MBCFHEDH_00522 5.2e-297 S dextransucrase activity
MBCFHEDH_00523 1.1e-110 tcyB_2 P ABC transporter (permease)
MBCFHEDH_00524 1.9e-116 gltJ P ABC transporter (Permease
MBCFHEDH_00525 2.4e-142 peb1A ET Belongs to the bacterial solute-binding protein 3 family
MBCFHEDH_00526 7.9e-64 glnQ 3.6.3.21 E abc transporter atp-binding protein
MBCFHEDH_00527 2.3e-145 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
MBCFHEDH_00528 8.4e-66 glnQ 3.6.3.21 E abc transporter atp-binding protein
MBCFHEDH_00536 6.8e-162 ppaC 3.6.1.1 C inorganic pyrophosphatase
MBCFHEDH_00537 2e-101 S Domain of unknown function (DUF1803)
MBCFHEDH_00538 7.8e-102 ygaC J Belongs to the UPF0374 family
MBCFHEDH_00539 5.2e-131 recX 2.4.1.337 GT4 S Regulatory protein RecX
MBCFHEDH_00540 2.9e-246 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MBCFHEDH_00541 1.4e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
MBCFHEDH_00542 1.7e-257 lysC 2.7.2.4 E Belongs to the aspartokinase family
MBCFHEDH_00543 6e-117 S HAD hydrolase, family IA, variant 3
MBCFHEDH_00544 6.2e-140 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
MBCFHEDH_00545 1.3e-70 marR K Transcriptional regulator, MarR family
MBCFHEDH_00546 1.9e-170 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MBCFHEDH_00547 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MBCFHEDH_00548 9.9e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
MBCFHEDH_00549 6.7e-162 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
MBCFHEDH_00550 8.1e-126 IQ reductase
MBCFHEDH_00551 9.8e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MBCFHEDH_00552 3.3e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MBCFHEDH_00553 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MBCFHEDH_00554 8.3e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MBCFHEDH_00555 2.7e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MBCFHEDH_00556 3.9e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MBCFHEDH_00557 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MBCFHEDH_00558 7.1e-207 rny D Endoribonuclease that initiates mRNA decay
MBCFHEDH_00559 5.9e-124 fruR K transcriptional
MBCFHEDH_00560 7.6e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MBCFHEDH_00561 0.0 fruA 2.7.1.202 G phosphotransferase system
MBCFHEDH_00562 5.3e-256 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MBCFHEDH_00563 1.9e-223 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MBCFHEDH_00565 4.4e-211 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
MBCFHEDH_00566 2.8e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MBCFHEDH_00567 4.3e-291 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MBCFHEDH_00568 4.1e-253 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
MBCFHEDH_00569 5.3e-82 2.3.1.128 K acetyltransferase
MBCFHEDH_00570 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
MBCFHEDH_00571 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MBCFHEDH_00572 1.6e-131 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MBCFHEDH_00573 5e-63 WQ51_03320 S cog cog4835
MBCFHEDH_00574 2.8e-146 XK27_08360 S EDD domain protein, DegV family
MBCFHEDH_00575 2.5e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MBCFHEDH_00576 2.5e-217 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MBCFHEDH_00577 0.0 yfmR S abc transporter atp-binding protein
MBCFHEDH_00578 1.7e-26 U response to pH
MBCFHEDH_00579 3.7e-129 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
MBCFHEDH_00580 3.6e-210 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
MBCFHEDH_00581 1.4e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
MBCFHEDH_00582 5.2e-266 S Psort location CytoplasmicMembrane, score
MBCFHEDH_00583 7.9e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
MBCFHEDH_00584 1.4e-72 K DNA-binding transcription factor activity
MBCFHEDH_00585 1.1e-309 lmrA1 V abc transporter atp-binding protein
MBCFHEDH_00586 0.0 lmrA2 V abc transporter atp-binding protein
MBCFHEDH_00587 1.3e-108 K Acetyltransferase (GNAT) family
MBCFHEDH_00588 2.8e-111 2.7.6.5 S Region found in RelA / SpoT proteins
MBCFHEDH_00589 6e-115 T response regulator
MBCFHEDH_00590 1.8e-210 sptS 2.7.13.3 T Histidine kinase
MBCFHEDH_00591 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MBCFHEDH_00592 1.7e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MBCFHEDH_00593 4.2e-158 cvfB S Protein conserved in bacteria
MBCFHEDH_00594 3.7e-34 yozE S Belongs to the UPF0346 family
MBCFHEDH_00595 9.4e-130 sip M LysM domain protein
MBCFHEDH_00596 2.4e-187 phoH T phosphate starvation-inducible protein PhoH
MBCFHEDH_00600 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MBCFHEDH_00601 1.1e-101 L DNA synthesis involved in DNA repair
MBCFHEDH_00602 5.8e-07 V HNH endonuclease
MBCFHEDH_00603 1.6e-155 L the current gene model (or a revised gene model) may contain a frame shift
MBCFHEDH_00604 2.4e-161 S reductase
MBCFHEDH_00605 4.7e-168 K transcriptional regulator (lysR family)
MBCFHEDH_00606 5.9e-108 S CAAX amino terminal protease family protein
MBCFHEDH_00607 1.8e-273 S Glucan-binding protein C
MBCFHEDH_00608 1e-165 coiA 3.6.4.12 S Competence protein
MBCFHEDH_00609 0.0 pepF E oligoendopeptidase F
MBCFHEDH_00610 6.5e-213 oxlT P COG0477 Permeases of the major facilitator superfamily
MBCFHEDH_00611 6.1e-120 yrrM 2.1.1.104 S O-Methyltransferase
MBCFHEDH_00612 1.1e-166 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
MBCFHEDH_00613 1e-84 yxjI S LURP-one-related
MBCFHEDH_00614 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MBCFHEDH_00617 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
MBCFHEDH_00618 1.4e-133 agrA KT phosphorelay signal transduction system
MBCFHEDH_00619 6.6e-227 2.7.13.3 T GHKL domain
MBCFHEDH_00620 9.8e-245 3.5.1.28 NU GBS Bsp-like repeat
MBCFHEDH_00622 0.0 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
MBCFHEDH_00623 4e-139 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MBCFHEDH_00624 3e-223 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
MBCFHEDH_00625 2.6e-183 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MBCFHEDH_00626 5.6e-217 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MBCFHEDH_00627 3.2e-122 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
MBCFHEDH_00628 5.3e-201 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
MBCFHEDH_00629 2.1e-136 yxkH G deacetylase
MBCFHEDH_00630 2.6e-236 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
MBCFHEDH_00631 2.2e-151 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MBCFHEDH_00632 5.7e-150 rarD S Transporter
MBCFHEDH_00633 1.7e-15 T peptidase
MBCFHEDH_00634 3e-14 coiA 3.6.4.12 S Competence protein
MBCFHEDH_00637 1.6e-100 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MBCFHEDH_00638 7.1e-98 2.3.1.128, 5.2.1.8 J Acetyltransferase (GNAT) domain
MBCFHEDH_00639 1.5e-15
MBCFHEDH_00640 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MBCFHEDH_00641 1.3e-291 S AAA ATPase domain
MBCFHEDH_00642 2.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MBCFHEDH_00643 9e-122 atpB C it plays a direct role in the translocation of protons across the membrane
MBCFHEDH_00644 2.1e-61 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MBCFHEDH_00645 1e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MBCFHEDH_00646 8.4e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MBCFHEDH_00647 6.2e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MBCFHEDH_00648 2.3e-262 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MBCFHEDH_00649 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MBCFHEDH_00650 2.7e-217 ftsW D Belongs to the SEDS family
MBCFHEDH_00651 1.6e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MBCFHEDH_00652 2.6e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MBCFHEDH_00653 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MBCFHEDH_00655 1e-108 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MBCFHEDH_00656 3.3e-158 holB 2.7.7.7 L dna polymerase iii
MBCFHEDH_00657 4.4e-133 yaaT S stage 0 sporulation protein
MBCFHEDH_00658 1.2e-54 yabA L Involved in initiation control of chromosome replication
MBCFHEDH_00659 3.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MBCFHEDH_00660 8.7e-26 amt P Ammonium Transporter
MBCFHEDH_00661 3.5e-104 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
MBCFHEDH_00662 4.9e-39 S HD domain
MBCFHEDH_00663 3.4e-40 S HD domain
MBCFHEDH_00664 6.4e-140 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
MBCFHEDH_00665 2e-75 S Bacterial inner membrane protein
MBCFHEDH_00666 5.2e-113 3.4.17.14, 3.5.1.28 NU amidase activity
MBCFHEDH_00667 3.5e-294 nptA P COG1283 Na phosphate symporter
MBCFHEDH_00668 1e-215 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MBCFHEDH_00669 1.3e-200 S membrane
MBCFHEDH_00670 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MBCFHEDH_00671 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MBCFHEDH_00672 1.7e-38 ynzC S UPF0291 protein
MBCFHEDH_00673 7.4e-253 cycA E permease
MBCFHEDH_00674 2.2e-10 uvrX 2.7.7.7 L impB/mucB/samB family
MBCFHEDH_00675 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
MBCFHEDH_00676 7.8e-140 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MBCFHEDH_00681 3.7e-157 V AAA domain, putative AbiEii toxin, Type IV TA system
MBCFHEDH_00682 5.8e-55 V ABC-2 type transporter
MBCFHEDH_00683 1.2e-95
MBCFHEDH_00685 9e-167 fhuR K transcriptional regulator (lysR family)
MBCFHEDH_00686 1.4e-75 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MBCFHEDH_00687 1.2e-160 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MBCFHEDH_00688 4.8e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MBCFHEDH_00689 4.7e-222 pyrP F uracil Permease
MBCFHEDH_00690 5e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MBCFHEDH_00691 9.3e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
MBCFHEDH_00692 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
MBCFHEDH_00693 4.7e-129 2.1.1.223 S Putative SAM-dependent methyltransferase
MBCFHEDH_00694 4.4e-180 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MBCFHEDH_00695 4.4e-121 macB V ABC transporter, ATP-binding protein
MBCFHEDH_00696 2.5e-209 V permease protein
MBCFHEDH_00697 2.8e-77 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MBCFHEDH_00698 2.1e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MBCFHEDH_00700 2.5e-273 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
MBCFHEDH_00701 4.6e-29 K DNA-binding transcription factor activity
MBCFHEDH_00702 0.0 mdlB V abc transporter atp-binding protein
MBCFHEDH_00703 0.0 lmrA V abc transporter atp-binding protein
MBCFHEDH_00704 6.6e-198 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MBCFHEDH_00705 3.4e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MBCFHEDH_00706 1.8e-197 yceA S Belongs to the UPF0176 family
MBCFHEDH_00707 1.6e-28 XK27_00085 K Transcriptional
MBCFHEDH_00708 1.2e-24
MBCFHEDH_00709 4.2e-141 deoD_1 2.4.2.3 F Phosphorylase superfamily
MBCFHEDH_00710 3.9e-114 S VIT family
MBCFHEDH_00711 2.2e-128 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MBCFHEDH_00712 3.5e-216 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MBCFHEDH_00713 3.7e-199 ald 1.4.1.1 C Belongs to the AlaDH PNT family
MBCFHEDH_00715 2.3e-121 E Alpha beta hydrolase
MBCFHEDH_00716 2.6e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MBCFHEDH_00717 3.8e-99 GBS0088 J protein conserved in bacteria
MBCFHEDH_00718 4.6e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
MBCFHEDH_00719 1.8e-170 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
MBCFHEDH_00720 2.4e-165 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
MBCFHEDH_00721 2.6e-183 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MBCFHEDH_00722 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
MBCFHEDH_00723 2.9e-257 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MBCFHEDH_00724 5.9e-97 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
MBCFHEDH_00725 7.1e-24
MBCFHEDH_00726 2.2e-117 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MBCFHEDH_00727 0.0 U protein secretion
MBCFHEDH_00728 8.3e-190 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
MBCFHEDH_00729 1.3e-243 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
MBCFHEDH_00730 6.8e-10
MBCFHEDH_00731 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MBCFHEDH_00732 2.9e-160 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MBCFHEDH_00733 1.2e-199 S Protein of unknown function (DUF3114)
MBCFHEDH_00734 4.1e-29 pspC KT PspC domain protein
MBCFHEDH_00735 5.2e-119 yqfA K protein, Hemolysin III
MBCFHEDH_00736 3.3e-77 K hmm pf08876
MBCFHEDH_00737 7.7e-225 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
MBCFHEDH_00738 9.3e-209 mvaS 2.3.3.10 I synthase
MBCFHEDH_00739 2.7e-165 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MBCFHEDH_00740 1.9e-89 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MBCFHEDH_00741 9.7e-22
MBCFHEDH_00742 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MBCFHEDH_00743 3.9e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
MBCFHEDH_00744 5.4e-248 mmuP E amino acid
MBCFHEDH_00745 1.1e-167 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
MBCFHEDH_00746 2.2e-30 S Domain of unknown function (DUF1912)
MBCFHEDH_00747 4e-12 L Helix-hairpin-helix DNA-binding motif class 1
MBCFHEDH_00748 5.6e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MBCFHEDH_00749 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MBCFHEDH_00751 1.3e-08
MBCFHEDH_00752 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MBCFHEDH_00753 9.1e-200 ilvE 2.6.1.42 E Aminotransferase
MBCFHEDH_00754 4.1e-15 S Protein of unknown function (DUF2969)
MBCFHEDH_00757 2.5e-204 rpsA 1.17.7.4 J ribosomal protein S1
MBCFHEDH_00760 4.6e-106 S Domain of Unknown Function with PDB structure (DUF3862)
MBCFHEDH_00761 8.7e-114 M Pfam SNARE associated Golgi protein
MBCFHEDH_00762 9.5e-228 murN 2.3.2.16 V FemAB family
MBCFHEDH_00763 7.5e-172 S oxidoreductase
MBCFHEDH_00764 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
MBCFHEDH_00765 2.2e-84 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
MBCFHEDH_00766 0.0 clpE O Belongs to the ClpA ClpB family
MBCFHEDH_00767 1.3e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MBCFHEDH_00768 1e-34 ykuJ S protein conserved in bacteria
MBCFHEDH_00769 5.8e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
MBCFHEDH_00770 1.4e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
MBCFHEDH_00771 2.7e-77 feoA P FeoA domain protein
MBCFHEDH_00772 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
MBCFHEDH_00773 6.6e-08
MBCFHEDH_00774 2.3e-147 I Alpha/beta hydrolase family
MBCFHEDH_00775 4.8e-154 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MBCFHEDH_00776 5.2e-145 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MBCFHEDH_00777 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
MBCFHEDH_00778 1.3e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MBCFHEDH_00779 3.3e-08 licT K antiterminator
MBCFHEDH_00780 2.1e-109 licT K antiterminator
MBCFHEDH_00781 3e-87 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MBCFHEDH_00782 4.4e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MBCFHEDH_00783 3.4e-166 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MBCFHEDH_00784 1.5e-141 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MBCFHEDH_00785 1.9e-93 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MBCFHEDH_00786 7.7e-222 mdtG EGP Major facilitator Superfamily
MBCFHEDH_00787 2e-33 secG U Preprotein translocase subunit SecG
MBCFHEDH_00788 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MBCFHEDH_00789 6.6e-81 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MBCFHEDH_00790 4.8e-276 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MBCFHEDH_00791 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
MBCFHEDH_00792 7.9e-194 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
MBCFHEDH_00793 1.2e-180 ccpA K Catabolite control protein A
MBCFHEDH_00794 1.9e-192 yyaQ S YjbR
MBCFHEDH_00795 5.3e-193 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MBCFHEDH_00796 4.5e-74 yueI S Protein of unknown function (DUF1694)
MBCFHEDH_00797 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MBCFHEDH_00798 4.6e-25 WQ51_00785
MBCFHEDH_00799 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MBCFHEDH_00800 1.1e-214 ywbD 2.1.1.191 J Methyltransferase
MBCFHEDH_00801 4.1e-116 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MBCFHEDH_00802 5.9e-152 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MBCFHEDH_00803 2.8e-199 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MBCFHEDH_00804 6.4e-218 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MBCFHEDH_00805 7e-206 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
MBCFHEDH_00806 4.2e-53 yheA S Belongs to the UPF0342 family
MBCFHEDH_00807 1.4e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MBCFHEDH_00808 2.1e-233 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MBCFHEDH_00809 4.7e-77 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MBCFHEDH_00810 1.4e-153 pheA 4.2.1.51 E Prephenate dehydratase
MBCFHEDH_00811 3.1e-238 msrR K Transcriptional regulator
MBCFHEDH_00812 1.2e-153 ydiA P C4-dicarboxylate transporter malic acid transport
MBCFHEDH_00813 4.2e-200 I acyl-CoA dehydrogenase
MBCFHEDH_00814 2e-97 mip S hydroperoxide reductase activity
MBCFHEDH_00815 1.6e-252 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MBCFHEDH_00816 1.9e-77 P Mediates zinc uptake. May also transport other divalent cations
MBCFHEDH_00817 2.4e-51 zupT P Mediates zinc uptake. May also transport other divalent cations
MBCFHEDH_00818 1.6e-61 smtB K Transcriptional regulator
MBCFHEDH_00819 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
MBCFHEDH_00820 4.3e-22
MBCFHEDH_00821 2e-217 EGP Transmembrane secretion effector
MBCFHEDH_00822 1e-257 yheS_2 S ATPase components of ABC transporters with duplicated ATPase domains
MBCFHEDH_00823 1.1e-49
MBCFHEDH_00824 8.7e-60
MBCFHEDH_00825 5.9e-55
MBCFHEDH_00826 1.5e-36 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MBCFHEDH_00827 9.1e-77 aacA7 2.3.1.82 K Acetyltransferase (GNAT) family
MBCFHEDH_00828 8.8e-81 3.4.13.21, 3.4.15.6 PQ Peptidase family S51
MBCFHEDH_00829 8.8e-113 K Bacterial regulatory proteins, tetR family
MBCFHEDH_00830 1.4e-112 S ABC-type transport system involved in multi-copper enzyme maturation, permease component
MBCFHEDH_00831 7.9e-129 bcrA V abc transporter atp-binding protein
MBCFHEDH_00832 7.7e-297 V ABC transporter transmembrane region
MBCFHEDH_00833 1.7e-12
MBCFHEDH_00834 1.4e-131 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MBCFHEDH_00835 1.7e-131 S Domain of unknown function (DUF4336)
MBCFHEDH_00836 6.5e-202 yeaN P transporter
MBCFHEDH_00837 5.1e-148 yitS S EDD domain protein, DegV family
MBCFHEDH_00838 5.8e-95 XK27_08140 K Bacterial regulatory proteins, tetR family
MBCFHEDH_00839 1.5e-95 ypgQ F HD superfamily hydrolase
MBCFHEDH_00840 7.5e-128 S CAAX amino terminal protease family
MBCFHEDH_00841 1.5e-107 cutC P Participates in the control of copper homeostasis
MBCFHEDH_00843 4.1e-21 S Domain of unknown function (DUF4767)
MBCFHEDH_00844 3.9e-283 norB P Major facilitator superfamily
MBCFHEDH_00845 6.3e-91 tetR K transcriptional regulator
MBCFHEDH_00846 2.1e-146 S Domain of unknown function (DUF4300)
MBCFHEDH_00847 1.5e-114 V CAAX protease self-immunity
MBCFHEDH_00848 1.4e-158 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MBCFHEDH_00849 8.3e-134 fecE 3.6.3.34 HP ABC transporter
MBCFHEDH_00850 1.1e-173 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
MBCFHEDH_00851 7.1e-124 ybbA S Putative esterase
MBCFHEDH_00852 3.3e-158 yegS 2.7.1.107 I Diacylglycerol kinase
MBCFHEDH_00853 4.7e-172 S Domain of unknown function (DUF389)
MBCFHEDH_00855 2.3e-29 S Membrane
MBCFHEDH_00856 4e-96
MBCFHEDH_00857 1.5e-22 S Small integral membrane protein
MBCFHEDH_00858 7.7e-68 S Asp23 family, cell envelope-related function
MBCFHEDH_00859 3.3e-08 K CsbD-like
MBCFHEDH_00860 3.3e-08 K CsbD-like
MBCFHEDH_00861 1e-174 pdhD 1.8.1.4 C Dehydrogenase
MBCFHEDH_00862 2.8e-167 acoA C Acetoin dehydrogenase E1 component subunit alpha
MBCFHEDH_00863 3.9e-174 acoB C dehydrogenase E1 component
MBCFHEDH_00864 1.2e-142 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MBCFHEDH_00865 8.1e-84 Q Methyltransferase domain
MBCFHEDH_00866 3.2e-56 K TetR family transcriptional regulator
MBCFHEDH_00867 5.4e-47
MBCFHEDH_00868 2.8e-129 V CAAX protease self-immunity
MBCFHEDH_00869 8.9e-11
MBCFHEDH_00870 2.6e-20 M Bacterial lipoprotein
MBCFHEDH_00871 6.4e-61 S Protein of unknown function (DUF1722)
MBCFHEDH_00872 4.8e-63 yqeB S Pyrimidine dimer DNA glycosylase
MBCFHEDH_00874 3.2e-51
MBCFHEDH_00875 4e-94 S CAAX protease self-immunity
MBCFHEDH_00876 1.6e-117 estA E GDSL-like Lipase/Acylhydrolase
MBCFHEDH_00877 9.6e-104
MBCFHEDH_00878 6e-286 sulP P Sulfate permease and related transporters (MFS superfamily)
MBCFHEDH_00879 1.5e-263 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MBCFHEDH_00880 7.3e-252 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MBCFHEDH_00881 9.3e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MBCFHEDH_00882 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MBCFHEDH_00883 2.2e-169 S CRISPR-associated protein Csn2 subfamily St
MBCFHEDH_00884 9.9e-149 ycgQ S TIGR03943 family
MBCFHEDH_00885 4.2e-156 XK27_03015 S permease
MBCFHEDH_00887 0.0 yhgF K Transcriptional accessory protein
MBCFHEDH_00888 2.2e-41 pspC KT PspC domain
MBCFHEDH_00889 8.3e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MBCFHEDH_00890 6.4e-145 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MBCFHEDH_00891 3.1e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MBCFHEDH_00892 2.3e-67 ytxH S General stress protein
MBCFHEDH_00894 1.5e-177 yegQ O Peptidase U32
MBCFHEDH_00895 1.7e-251 yegQ O Peptidase U32
MBCFHEDH_00896 1.1e-87 bioY S biotin synthase
MBCFHEDH_00898 1.1e-33 XK27_12190 S protein conserved in bacteria
MBCFHEDH_00899 4.3e-234 mntH P H( )-stimulated, divalent metal cation uptake system
MBCFHEDH_00900 2.8e-11
MBCFHEDH_00901 1.6e-14
MBCFHEDH_00902 7.1e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MBCFHEDH_00903 6.3e-137 M LysM domain
MBCFHEDH_00904 8.4e-23
MBCFHEDH_00905 5.2e-175 S hydrolase
MBCFHEDH_00907 3.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
MBCFHEDH_00908 2.5e-80 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MBCFHEDH_00909 9.4e-140 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
MBCFHEDH_00910 3e-26 P Hemerythrin HHE cation binding domain protein
MBCFHEDH_00911 4.3e-155 5.2.1.8 G hydrolase
MBCFHEDH_00912 5.2e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MBCFHEDH_00913 3.8e-194 MA20_36090 S Protein of unknown function (DUF2974)
MBCFHEDH_00914 2.9e-134 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MBCFHEDH_00915 1e-43 S Nucleotide pyrophosphohydrolase
MBCFHEDH_00916 1.2e-188 L Uncharacterized conserved protein (DUF2075)
MBCFHEDH_00917 5.4e-132 S double-stranded DNA endodeoxyribonuclease activity
MBCFHEDH_00918 0.0 M Right handed beta helix region
MBCFHEDH_00919 1.9e-30 2.4.1.21 GT5 M Right handed beta helix region
MBCFHEDH_00920 2.2e-166 spd F DNA RNA non-specific endonuclease
MBCFHEDH_00921 7.7e-92 lemA S LemA family
MBCFHEDH_00922 1.3e-133 htpX O Belongs to the peptidase M48B family
MBCFHEDH_00923 2e-112 sirR K iron dependent repressor
MBCFHEDH_00924 1.8e-167 sitA P Belongs to the bacterial solute-binding protein 9 family
MBCFHEDH_00925 2.3e-132 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
MBCFHEDH_00926 1.6e-126 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
MBCFHEDH_00927 6.1e-74 S Psort location CytoplasmicMembrane, score
MBCFHEDH_00928 6.2e-64 S Domain of unknown function (DUF4430)
MBCFHEDH_00929 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MBCFHEDH_00930 2.2e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
MBCFHEDH_00931 6.1e-111 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
MBCFHEDH_00932 1.4e-163 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
MBCFHEDH_00933 3.1e-100 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
MBCFHEDH_00934 9e-79 dps P Belongs to the Dps family
MBCFHEDH_00935 3.4e-79 perR P Belongs to the Fur family
MBCFHEDH_00936 4.2e-27 yqgQ S protein conserved in bacteria
MBCFHEDH_00937 1.1e-175 glk 2.7.1.2 G Glucokinase
MBCFHEDH_00938 0.0 typA T GTP-binding protein TypA
MBCFHEDH_00940 9e-248 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MBCFHEDH_00941 1.2e-197 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MBCFHEDH_00942 7.4e-134 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MBCFHEDH_00943 1e-222 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MBCFHEDH_00944 2.8e-233 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MBCFHEDH_00945 1.9e-121 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MBCFHEDH_00946 3.4e-90 sepF D cell septum assembly
MBCFHEDH_00947 1.7e-30 yggT D integral membrane protein
MBCFHEDH_00948 8.6e-137 ylmH S conserved protein, contains S4-like domain
MBCFHEDH_00949 5.5e-137 divIVA D Cell division initiation protein
MBCFHEDH_00950 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MBCFHEDH_00951 3.8e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MBCFHEDH_00952 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MBCFHEDH_00953 6.5e-34 nrdH O Glutaredoxin
MBCFHEDH_00954 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MBCFHEDH_00955 2.4e-209 citZ 2.3.3.1 C Belongs to the citrate synthase family
MBCFHEDH_00956 7.7e-219 icd 1.1.1.42 C Isocitrate dehydrogenase
MBCFHEDH_00957 3e-38 ptsH G phosphocarrier protein Hpr
MBCFHEDH_00958 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MBCFHEDH_00959 6.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
MBCFHEDH_00960 5.1e-161 XK27_05670 S Putative esterase
MBCFHEDH_00961 2.7e-153 XK27_05675 S Esterase
MBCFHEDH_00962 5.4e-225 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
MBCFHEDH_00963 8.7e-177 yfmL 3.6.4.13 L DEAD DEAH box helicase
MBCFHEDH_00964 6.8e-113 udk 2.7.1.48 F Cytidine monophosphokinase
MBCFHEDH_00965 0.0 uup S abc transporter atp-binding protein
MBCFHEDH_00966 1.6e-39 MA20_06245 S yiaA/B two helix domain
MBCFHEDH_00967 1.7e-131 pip 1.11.1.10 S Alpha beta hydrolase
MBCFHEDH_00968 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MBCFHEDH_00969 6.2e-148 cobQ S glutamine amidotransferase
MBCFHEDH_00970 5.4e-253 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
MBCFHEDH_00971 1.1e-147 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MBCFHEDH_00972 1.1e-162 ybbR S Protein conserved in bacteria
MBCFHEDH_00973 1.3e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MBCFHEDH_00974 1.3e-64 gtrA S GtrA-like protein
MBCFHEDH_00975 1.1e-119 trmK 2.1.1.217 S SAM-dependent methyltransferase
MBCFHEDH_00976 1.7e-142 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MBCFHEDH_00977 1.1e-142 zupT P Mediates zinc uptake. May also transport other divalent cations
MBCFHEDH_00978 1.9e-200 yurR 1.4.5.1 E oxidoreductase
MBCFHEDH_00979 1.9e-258 S phospholipase Carboxylesterase
MBCFHEDH_00980 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MBCFHEDH_00981 1.9e-112 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MBCFHEDH_00982 1.3e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MBCFHEDH_00984 5.4e-29 KT response to antibiotic
MBCFHEDH_00985 2.5e-214 hemN H Involved in the biosynthesis of porphyrin-containing compound
MBCFHEDH_00986 1.1e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
MBCFHEDH_00987 1.2e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MBCFHEDH_00988 3.7e-114 ylfI S tigr01906
MBCFHEDH_00989 8.7e-136 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
MBCFHEDH_00990 1.6e-147 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
MBCFHEDH_00991 2.9e-58 XK27_08085
MBCFHEDH_00992 1.9e-192 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MBCFHEDH_00993 9e-181 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MBCFHEDH_00994 8e-117 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MBCFHEDH_00995 5.4e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MBCFHEDH_00996 3.9e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
MBCFHEDH_00997 2.6e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MBCFHEDH_00998 2.2e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MBCFHEDH_00999 2.1e-137 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MBCFHEDH_01000 1.1e-58 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MBCFHEDH_01001 4.1e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
MBCFHEDH_01003 7.6e-94 XK27_05505 S Psort location CytoplasmicMembrane, score
MBCFHEDH_01004 1.8e-144 P molecular chaperone
MBCFHEDH_01005 1.8e-96 S Carbohydrate-binding domain-containing protein Cthe_2159
MBCFHEDH_01006 5.2e-179 XK27_08075 M glycosyl transferase family 2
MBCFHEDH_01007 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
MBCFHEDH_01008 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
MBCFHEDH_01009 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
MBCFHEDH_01010 3.2e-227 rodA D Belongs to the SEDS family
MBCFHEDH_01011 2.4e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MBCFHEDH_01012 1.5e-112 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
MBCFHEDH_01013 2.7e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MBCFHEDH_01014 3.7e-137 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MBCFHEDH_01015 4.1e-19 Q Methyltransferase domain
MBCFHEDH_01016 1.5e-65 GnaT 2.5.1.16 K acetyltransferase
MBCFHEDH_01017 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
MBCFHEDH_01018 1.7e-93 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MBCFHEDH_01019 1.8e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MBCFHEDH_01020 1.3e-125 dnaD
MBCFHEDH_01021 1.3e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MBCFHEDH_01023 6.2e-233 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MBCFHEDH_01024 4.6e-29 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MBCFHEDH_01025 5.2e-156 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MBCFHEDH_01026 1.5e-147 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MBCFHEDH_01027 2.8e-73 argR K Regulates arginine biosynthesis genes
MBCFHEDH_01028 5.6e-300 recN L May be involved in recombinational repair of damaged DNA
MBCFHEDH_01029 6.9e-145 DegV S DegV family
MBCFHEDH_01030 1.5e-155 ypmR E COG2755 Lysophospholipase L1 and related esterases
MBCFHEDH_01031 1.3e-94 ypmS S Protein conserved in bacteria
MBCFHEDH_01032 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MBCFHEDH_01034 2.3e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
MBCFHEDH_01035 3.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MBCFHEDH_01036 2e-52 hxlR K HxlR-like helix-turn-helix
MBCFHEDH_01037 2e-70 S SnoaL-like polyketide cyclase
MBCFHEDH_01038 8.1e-54 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MBCFHEDH_01039 2.4e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MBCFHEDH_01040 6.2e-188 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MBCFHEDH_01041 4.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MBCFHEDH_01042 2.4e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MBCFHEDH_01043 0.0 dnaE 2.7.7.7 L DNA polymerase
MBCFHEDH_01044 1e-187 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MBCFHEDH_01045 2.7e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MBCFHEDH_01046 8.8e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MBCFHEDH_01048 1.1e-125 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MBCFHEDH_01049 1.3e-09 O ADP-ribosylglycohydrolase
MBCFHEDH_01050 1.9e-62 paaI Q protein possibly involved in aromatic compounds catabolism
MBCFHEDH_01051 1.3e-60 ycaO O OsmC-like protein
MBCFHEDH_01053 2e-150 EG Permeases of the drug metabolite transporter (DMT) superfamily
MBCFHEDH_01054 1e-08 N PFAM Uncharacterised protein family UPF0150
MBCFHEDH_01055 1.6e-104 csn2 S CRISPR-associated protein (Cas_Csn2)
MBCFHEDH_01056 3.2e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MBCFHEDH_01057 4.1e-161 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MBCFHEDH_01058 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MBCFHEDH_01059 2.9e-111 serB 3.1.3.3 E phosphoserine phosphatase
MBCFHEDH_01060 3.2e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MBCFHEDH_01061 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MBCFHEDH_01062 2.9e-105 3.1.3.18 S IA, variant 1
MBCFHEDH_01063 1.9e-116 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MBCFHEDH_01064 5.9e-56 lrgA S Effector of murein hydrolase LrgA
MBCFHEDH_01066 5.4e-59 arsC 1.20.4.1 P Belongs to the ArsC family
MBCFHEDH_01067 7e-73 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
MBCFHEDH_01068 4.5e-219 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MBCFHEDH_01069 6.9e-101 wecD M Acetyltransferase (GNAT) domain
MBCFHEDH_01070 5.1e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MBCFHEDH_01071 1.9e-153 GK ROK family
MBCFHEDH_01072 1.8e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
MBCFHEDH_01073 1.9e-145 XK27_08050 O HflC and HflK could regulate a protease
MBCFHEDH_01074 8.3e-204 potD P spermidine putrescine ABC transporter
MBCFHEDH_01075 2.3e-131 potC P ABC-type spermidine putrescine transport system, permease component II
MBCFHEDH_01076 4.1e-139 potB P ABC-type spermidine putrescine transport system, permease component I
MBCFHEDH_01077 2.6e-211 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MBCFHEDH_01078 5.8e-166 murB 1.3.1.98 M cell wall formation
MBCFHEDH_01079 1.6e-77 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MBCFHEDH_01080 2.5e-59 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MBCFHEDH_01081 5.3e-294 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
MBCFHEDH_01082 1.3e-145 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MBCFHEDH_01083 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
MBCFHEDH_01084 0.0 ydaO E amino acid
MBCFHEDH_01085 7.7e-233 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MBCFHEDH_01086 1.5e-36 ylqC L Belongs to the UPF0109 family
MBCFHEDH_01087 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MBCFHEDH_01089 1.5e-210 2.7.13.3 T protein histidine kinase activity
MBCFHEDH_01090 2.2e-123 agrA KT phosphorelay signal transduction system
MBCFHEDH_01091 4.2e-165 O protein import
MBCFHEDH_01092 4.3e-166 tehB 2.1.1.265 PQ tellurite resistance protein tehb
MBCFHEDH_01093 3.7e-17 yjdB S Domain of unknown function (DUF4767)
MBCFHEDH_01094 9.5e-64 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MBCFHEDH_01096 7.7e-157 xth 3.1.11.2 L exodeoxyribonuclease III
MBCFHEDH_01097 3.9e-68 S QueT transporter
MBCFHEDH_01099 4.5e-172 yfjR K regulation of single-species biofilm formation
MBCFHEDH_01101 3.1e-184 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MBCFHEDH_01102 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MBCFHEDH_01103 2.8e-85 ccl S cog cog4708
MBCFHEDH_01104 8.4e-160 rbn E Belongs to the UPF0761 family
MBCFHEDH_01105 1.1e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
MBCFHEDH_01106 3e-232 ytoI K transcriptional regulator containing CBS domains
MBCFHEDH_01107 3.5e-97 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
MBCFHEDH_01108 2.3e-229 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MBCFHEDH_01109 0.0 comEC S Competence protein ComEC
MBCFHEDH_01110 3.7e-88 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
MBCFHEDH_01111 2.9e-142 plsC 2.3.1.51 I Acyltransferase
MBCFHEDH_01112 7.4e-148 nodB3 G Polysaccharide deacetylase
MBCFHEDH_01113 4.6e-140 yabB 2.1.1.223 L Methyltransferase
MBCFHEDH_01114 1e-41 yazA L endonuclease containing a URI domain
MBCFHEDH_01115 2.2e-245 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MBCFHEDH_01116 4e-151 corA P CorA-like protein
MBCFHEDH_01117 9.6e-62 yjqA S Bacterial PH domain
MBCFHEDH_01118 2e-95 thiT S Thiamine transporter
MBCFHEDH_01119 1.5e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
MBCFHEDH_01120 3.7e-197 yjbB G Permeases of the major facilitator superfamily
MBCFHEDH_01121 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MBCFHEDH_01122 2.1e-117 ywaF S Integral membrane protein (intg_mem_TP0381)
MBCFHEDH_01123 9.5e-253 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MBCFHEDH_01127 9.7e-155 cjaA ET ABC transporter substrate-binding protein
MBCFHEDH_01128 7.6e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
MBCFHEDH_01129 3e-106 P ABC transporter (Permease
MBCFHEDH_01130 2.5e-113 papP P ABC transporter (Permease
MBCFHEDH_01131 6.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MBCFHEDH_01132 1.5e-56
MBCFHEDH_01133 2.9e-83 V ABC transporter
MBCFHEDH_01134 2.5e-34 K Transcriptional regulator C-terminal region
MBCFHEDH_01135 2.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
MBCFHEDH_01136 0.0 copA 3.6.3.54 P P-type ATPase
MBCFHEDH_01137 6.1e-73 copY K negative regulation of transcription, DNA-templated
MBCFHEDH_01138 5e-162 EGP Major facilitator Superfamily
MBCFHEDH_01140 2.5e-141 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MBCFHEDH_01141 1.4e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MBCFHEDH_01142 1e-99 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
MBCFHEDH_01143 1.4e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
MBCFHEDH_01144 5.6e-178 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MBCFHEDH_01145 8e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
MBCFHEDH_01146 3.1e-256 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MBCFHEDH_01147 2.2e-39 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
MBCFHEDH_01148 2.2e-58
MBCFHEDH_01149 0.0 ctpE P E1-E2 ATPase
MBCFHEDH_01150 3.7e-45
MBCFHEDH_01151 6.7e-26 L Transposase
MBCFHEDH_01152 2.2e-60 fruR K transcriptional
MBCFHEDH_01153 2.2e-35 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MBCFHEDH_01154 4.4e-162 T Diguanylate cyclase
MBCFHEDH_01155 1.1e-150 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
MBCFHEDH_01156 0.0 bcsA 2.4.1.12 GT2 M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
MBCFHEDH_01157 0.0
MBCFHEDH_01160 1.1e-47
MBCFHEDH_01161 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MBCFHEDH_01163 9.5e-124 V abc transporter atp-binding protein
MBCFHEDH_01164 0.0 V ABC transporter (Permease
MBCFHEDH_01165 8.9e-125 K transcriptional regulator, MerR family
MBCFHEDH_01166 4.9e-105 dnaQ 2.7.7.7 L DNA polymerase III
MBCFHEDH_01167 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
MBCFHEDH_01168 9.6e-64 XK27_02560 S cog cog2151
MBCFHEDH_01169 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
MBCFHEDH_01170 3.9e-212 ytfP S Flavoprotein
MBCFHEDH_01171 2.7e-222 L the current gene model (or a revised gene model) may contain a frame shift
MBCFHEDH_01173 2.6e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MBCFHEDH_01174 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
MBCFHEDH_01175 1e-174 ecsB U Bacterial ABC transporter protein EcsB
MBCFHEDH_01176 3.7e-131 ecsA V abc transporter atp-binding protein
MBCFHEDH_01177 1e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MBCFHEDH_01178 4.1e-07
MBCFHEDH_01181 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
MBCFHEDH_01182 3.9e-43 yoeB S Addiction module toxin, Txe YoeB family
MBCFHEDH_01183 7.6e-39 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
MBCFHEDH_01184 1.2e-194 ylbM S Belongs to the UPF0348 family
MBCFHEDH_01185 2.9e-139 yqeM Q Methyltransferase domain protein
MBCFHEDH_01186 2e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MBCFHEDH_01187 8.3e-105 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
MBCFHEDH_01188 3.5e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MBCFHEDH_01189 7.7e-49 yhbY J RNA-binding protein
MBCFHEDH_01190 1.6e-213 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MBCFHEDH_01191 2.3e-98 yqeG S hydrolase of the HAD superfamily
MBCFHEDH_01192 3.7e-152 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MBCFHEDH_01193 9.3e-65
MBCFHEDH_01194 1.9e-272 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MBCFHEDH_01195 1.3e-268 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MBCFHEDH_01196 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MBCFHEDH_01197 3.6e-234 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MBCFHEDH_01198 2.6e-191 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
MBCFHEDH_01199 5.7e-158 H COG0463 Glycosyltransferases involved in cell wall biogenesis
MBCFHEDH_01200 5.7e-217 M lipopolysaccharide 3-alpha-galactosyltransferase activity
MBCFHEDH_01201 2.2e-292 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MBCFHEDH_01202 4.4e-100 pncA Q isochorismatase
MBCFHEDH_01203 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MBCFHEDH_01204 1.7e-237 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
MBCFHEDH_01205 9e-75 XK27_03180 T universal stress protein
MBCFHEDH_01207 1.5e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MBCFHEDH_01208 1.4e-08 MU outer membrane autotransporter barrel domain protein
MBCFHEDH_01209 3.2e-237 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
MBCFHEDH_01210 1.2e-140 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
MBCFHEDH_01212 1.8e-24
MBCFHEDH_01214 0.0 yjcE P NhaP-type Na H and K H antiporters
MBCFHEDH_01216 1.9e-95 ytqB J (SAM)-dependent
MBCFHEDH_01217 1e-181 yhcC S radical SAM protein
MBCFHEDH_01218 3.2e-187 ylbL T Belongs to the peptidase S16 family
MBCFHEDH_01219 1.9e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MBCFHEDH_01220 9.6e-92 rsmD 2.1.1.171 L Methyltransferase
MBCFHEDH_01221 2.1e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MBCFHEDH_01222 5e-10 S Protein of unknown function (DUF4059)
MBCFHEDH_01223 5.2e-128 tcyN 3.6.3.21 E abc transporter atp-binding protein
MBCFHEDH_01224 1.4e-162 yxeN P ABC transporter (Permease
MBCFHEDH_01225 9.7e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
MBCFHEDH_01226 8e-35
MBCFHEDH_01227 7.3e-203 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MBCFHEDH_01228 0.0 pflB 2.3.1.54 C formate acetyltransferase'
MBCFHEDH_01229 1.9e-141 cah 4.2.1.1 P carbonic anhydrase
MBCFHEDH_01230 1.1e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MBCFHEDH_01232 3.1e-170 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
MBCFHEDH_01233 4.7e-137 cppA E CppA N-terminal
MBCFHEDH_01234 1.2e-93 V CAAX protease self-immunity
MBCFHEDH_01235 5.6e-150 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
MBCFHEDH_01236 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MBCFHEDH_01240 9.2e-44 spiA K sequence-specific DNA binding
MBCFHEDH_01247 0.0 mdlB V abc transporter atp-binding protein
MBCFHEDH_01248 0.0 mdlA V abc transporter atp-binding protein
MBCFHEDH_01251 1.2e-91 XK27_09885 V Glycopeptide antibiotics resistance protein
MBCFHEDH_01252 3.9e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MBCFHEDH_01253 2e-60 yutD J protein conserved in bacteria
MBCFHEDH_01254 3.7e-249 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
MBCFHEDH_01256 3e-213 T GHKL domain
MBCFHEDH_01257 2.3e-128 KT COG3279 Response regulator of the LytR AlgR family
MBCFHEDH_01258 3.9e-123
MBCFHEDH_01259 6.6e-151 V ATPases associated with a variety of cellular activities
MBCFHEDH_01260 3.6e-220 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MBCFHEDH_01261 7e-184 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MBCFHEDH_01262 0.0 ftsI 3.4.16.4 M penicillin-binding protein
MBCFHEDH_01263 2.4e-45 ftsL D cell division protein FtsL
MBCFHEDH_01264 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MBCFHEDH_01265 2.2e-08
MBCFHEDH_01266 5.2e-63
MBCFHEDH_01269 1.4e-42 yhaI J Protein of unknown function (DUF805)
MBCFHEDH_01270 1.3e-61 yhaI J Protein of unknown function (DUF805)
MBCFHEDH_01271 8.9e-55 yhaI J Membrane
MBCFHEDH_01272 3.9e-221 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MBCFHEDH_01273 6.3e-140 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MBCFHEDH_01274 1.4e-284 XK27_00765
MBCFHEDH_01275 4e-133 ecsA_2 V abc transporter atp-binding protein
MBCFHEDH_01276 4e-125 S Protein of unknown function (DUF554)
MBCFHEDH_01277 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MBCFHEDH_01278 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
MBCFHEDH_01279 2.9e-233 2.7.13.3 T protein histidine kinase activity
MBCFHEDH_01280 7.2e-226 dcuS 2.7.13.3 T protein histidine kinase activity
MBCFHEDH_01281 6.8e-14
MBCFHEDH_01284 1.3e-145 V Psort location CytoplasmicMembrane, score
MBCFHEDH_01286 1.7e-298 O MreB/Mbl protein
MBCFHEDH_01287 4.7e-196 mccF V the current gene model (or a revised gene model) may contain a frame shift
MBCFHEDH_01288 4e-43 S Sugar efflux transporter for intercellular exchange
MBCFHEDH_01289 6.2e-76 mccF V LD-carboxypeptidase
MBCFHEDH_01290 4.8e-120 liaI S membrane
MBCFHEDH_01291 1.5e-74 XK27_02470 K LytTr DNA-binding domain
MBCFHEDH_01292 1.2e-310 KT response to antibiotic
MBCFHEDH_01293 1.6e-102 yebC M Membrane
MBCFHEDH_01294 1.4e-259 XK27_03190 S hydrolases of the HAD superfamily
MBCFHEDH_01295 4.6e-177 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MBCFHEDH_01297 1.8e-156 K Helix-turn-helix XRE-family like proteins
MBCFHEDH_01298 4.7e-280 V ABC transporter transmembrane region
MBCFHEDH_01299 2.4e-30 yozG K Transcriptional regulator
MBCFHEDH_01303 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MBCFHEDH_01304 2.5e-203 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MBCFHEDH_01305 3.4e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MBCFHEDH_01306 1.4e-195 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MBCFHEDH_01307 1.9e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MBCFHEDH_01308 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MBCFHEDH_01310 1.9e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
MBCFHEDH_01311 6.5e-170 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
MBCFHEDH_01312 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
MBCFHEDH_01313 2.6e-285 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
MBCFHEDH_01314 7.5e-180 scrR K Transcriptional regulator
MBCFHEDH_01315 8.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MBCFHEDH_01316 1.7e-61 yqhY S protein conserved in bacteria
MBCFHEDH_01317 7.1e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MBCFHEDH_01318 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
MBCFHEDH_01319 2e-186 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
MBCFHEDH_01321 5.1e-145 V 'abc transporter, ATP-binding protein
MBCFHEDH_01322 2.1e-32 blpT
MBCFHEDH_01326 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MBCFHEDH_01327 4.2e-167 corA P COG0598 Mg2 and Co2 transporters
MBCFHEDH_01328 8.5e-122 XK27_01040 S Protein of unknown function (DUF1129)
MBCFHEDH_01330 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MBCFHEDH_01331 2.5e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MBCFHEDH_01332 3e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
MBCFHEDH_01333 7.2e-42 XK27_05745
MBCFHEDH_01334 4.9e-218 mutY L A G-specific adenine glycosylase
MBCFHEDH_01336 3.7e-34
MBCFHEDH_01338 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MBCFHEDH_01339 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MBCFHEDH_01340 6.7e-93 cvpA S toxin biosynthetic process
MBCFHEDH_01341 9.3e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MBCFHEDH_01342 5.4e-153 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MBCFHEDH_01343 6.1e-106 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MBCFHEDH_01344 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MBCFHEDH_01345 4.4e-47 azlD S branched-chain amino acid
MBCFHEDH_01346 2.8e-112 azlC E AzlC protein
MBCFHEDH_01347 1.3e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MBCFHEDH_01348 4.8e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MBCFHEDH_01349 1.5e-118 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
MBCFHEDH_01350 1.5e-33 ykzG S Belongs to the UPF0356 family
MBCFHEDH_01351 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MBCFHEDH_01352 1.4e-223 L Transposase
MBCFHEDH_01353 1.6e-114 pscB M CHAP domain protein
MBCFHEDH_01354 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
MBCFHEDH_01355 2.5e-62 glnR K Transcriptional regulator
MBCFHEDH_01356 3e-87 S Fusaric acid resistance protein-like
MBCFHEDH_01357 5.8e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MBCFHEDH_01358 3.4e-121
MBCFHEDH_01359 7.1e-181 gap 1.2.1.12 C Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
MBCFHEDH_01360 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MBCFHEDH_01361 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MBCFHEDH_01362 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MBCFHEDH_01363 4e-142 purR 2.4.2.7 F operon repressor
MBCFHEDH_01364 3.1e-178 cbf S 3'-5' exoribonuclease yhaM
MBCFHEDH_01365 7.9e-169 rmuC S RmuC domain protein
MBCFHEDH_01366 4e-113 thiN 2.7.6.2 H thiamine pyrophosphokinase
MBCFHEDH_01367 7.8e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MBCFHEDH_01368 9.2e-161 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MBCFHEDH_01370 2.4e-153 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MBCFHEDH_01371 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MBCFHEDH_01372 6.8e-142 tatD L Hydrolase, tatd
MBCFHEDH_01373 3.7e-70 yccU S CoA-binding protein
MBCFHEDH_01374 5.3e-50 trxA O Belongs to the thioredoxin family
MBCFHEDH_01375 3.3e-141 S Macro domain protein
MBCFHEDH_01376 8.2e-59 L thioesterase
MBCFHEDH_01377 1.3e-49 bta 1.8.1.8 CO cell redox homeostasis
MBCFHEDH_01380 8.6e-87 sigH K DNA-templated transcription, initiation
MBCFHEDH_01381 6e-135 ykuT M mechanosensitive ion channel
MBCFHEDH_01382 5.8e-228 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MBCFHEDH_01383 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MBCFHEDH_01384 3.7e-309 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MBCFHEDH_01385 6.4e-84 XK27_03960 S Protein of unknown function (DUF3013)
MBCFHEDH_01386 2.2e-78 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
MBCFHEDH_01387 1.3e-57 XK27_02675 K Acetyltransferase GNAT Family
MBCFHEDH_01388 3.5e-177 prmA J Ribosomal protein L11 methyltransferase
MBCFHEDH_01389 7.7e-132 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MBCFHEDH_01390 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
MBCFHEDH_01391 9.1e-83 nrdI F Belongs to the NrdI family
MBCFHEDH_01392 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MBCFHEDH_01393 9.7e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MBCFHEDH_01394 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
MBCFHEDH_01395 8.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MBCFHEDH_01396 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MBCFHEDH_01397 1.3e-111 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
MBCFHEDH_01398 3e-191 yhjX P Major Facilitator
MBCFHEDH_01399 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MBCFHEDH_01400 1.4e-177 D nuclear chromosome segregation
MBCFHEDH_01401 2.2e-123 glnQ E abc transporter atp-binding protein
MBCFHEDH_01402 4.3e-270 glnP P ABC transporter
MBCFHEDH_01403 3.4e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MBCFHEDH_01404 2.4e-17 S Protein of unknown function (DUF3021)
MBCFHEDH_01405 2.9e-123 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MBCFHEDH_01406 5.7e-182 tagO 2.7.8.33, 2.7.8.35 M transferase
MBCFHEDH_01407 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MBCFHEDH_01408 6.9e-234 sufD O assembly protein SufD
MBCFHEDH_01409 3.4e-233 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MBCFHEDH_01410 8e-73 nifU C SUF system FeS assembly protein, NifU family
MBCFHEDH_01411 2.9e-273 sufB O assembly protein SufB
MBCFHEDH_01412 9.4e-27
MBCFHEDH_01413 2.1e-157 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MBCFHEDH_01414 2.8e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MBCFHEDH_01415 1.7e-70 adcR K transcriptional
MBCFHEDH_01416 9.2e-135 adcC P ABC transporter, ATP-binding protein
MBCFHEDH_01417 4.3e-128 adcB P ABC transporter (Permease
MBCFHEDH_01418 5.5e-159 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
MBCFHEDH_01419 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
MBCFHEDH_01420 4.6e-154 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
MBCFHEDH_01421 4.2e-253 pgi 5.3.1.9 G Belongs to the GPI family
MBCFHEDH_01422 1.4e-142 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MBCFHEDH_01423 0.0 srlM 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
MBCFHEDH_01424 6.8e-84 gutM K phosphoenolpyruvate-dependent sugar phosphotransferase system
MBCFHEDH_01425 1.1e-95 srlA G PTS system glucitol sorbitol-specific
MBCFHEDH_01426 3.8e-179 srlE 2.7.1.198 G PTS sorbitol transporter subunit IIB
MBCFHEDH_01427 4.2e-59 srlB 2.7.1.198 G sorbitol-specific, IIA component
MBCFHEDH_01428 8.1e-16 tnp* L An automated process has identified a potential problem with this gene model
MBCFHEDH_01429 9.2e-59 L MULE transposase domain
MBCFHEDH_01430 1.1e-108 L Transposase IS116 IS110 IS902
MBCFHEDH_01431 1.3e-305 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MBCFHEDH_01432 8.2e-219 L the current gene model (or a revised gene model) may contain a frame shift
MBCFHEDH_01433 1.4e-153 Z012_04635 K sequence-specific DNA binding
MBCFHEDH_01434 1.1e-276 V ABC transporter
MBCFHEDH_01435 6.1e-126 yeeN K transcriptional regulatory protein
MBCFHEDH_01436 2e-47 yajC U protein transport
MBCFHEDH_01437 5.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MBCFHEDH_01438 4.6e-143 cdsA 2.7.7.41 S Belongs to the CDS family
MBCFHEDH_01439 1.4e-229 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
MBCFHEDH_01440 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MBCFHEDH_01441 0.0 WQ51_06230 S ABC transporter
MBCFHEDH_01442 3e-142 cmpC S abc transporter atp-binding protein
MBCFHEDH_01443 4.9e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MBCFHEDH_01444 6.5e-285 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MBCFHEDH_01446 1.9e-44
MBCFHEDH_01447 5.8e-55 S TM2 domain
MBCFHEDH_01448 1.4e-161 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MBCFHEDH_01449 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MBCFHEDH_01450 6.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MBCFHEDH_01451 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
MBCFHEDH_01452 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
MBCFHEDH_01453 6.9e-65 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
MBCFHEDH_01454 2.8e-143 cof S Sucrose-6F-phosphate phosphohydrolase
MBCFHEDH_01455 3.6e-132 glcR K transcriptional regulator (DeoR family)
MBCFHEDH_01456 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MBCFHEDH_01457 8.4e-73 K transcriptional
MBCFHEDH_01458 6.6e-221 S COG1073 Hydrolases of the alpha beta superfamily
MBCFHEDH_01459 6.8e-156 cylA V abc transporter atp-binding protein
MBCFHEDH_01460 1e-132 cylB V ABC-2 type transporter
MBCFHEDH_01461 1.3e-73 K COG3279 Response regulator of the LytR AlgR family
MBCFHEDH_01462 4.8e-30 S Protein of unknown function (DUF3021)
MBCFHEDH_01463 1.4e-114 mta K Transcriptional
MBCFHEDH_01464 8.1e-120 yhcA V abc transporter atp-binding protein
MBCFHEDH_01465 8.3e-208 macB_2 V FtsX-like permease family
MBCFHEDH_01466 9.7e-272 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MBCFHEDH_01467 2.2e-148 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MBCFHEDH_01468 2e-71 yhaI S Protein of unknown function (DUF805)
MBCFHEDH_01469 3.8e-254 pepC 3.4.22.40 E aminopeptidase
MBCFHEDH_01470 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MBCFHEDH_01471 4.3e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MBCFHEDH_01472 1.7e-93 ypsA S Belongs to the UPF0398 family
MBCFHEDH_01473 2.1e-36 gpsB D regulation of cell shape
MBCFHEDH_01474 1.8e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MBCFHEDH_01475 1e-279 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
MBCFHEDH_01476 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
MBCFHEDH_01477 4.8e-22
MBCFHEDH_01478 3.4e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MBCFHEDH_01479 2.7e-85 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
MBCFHEDH_01480 7.2e-294 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MBCFHEDH_01481 4.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MBCFHEDH_01482 1.4e-162 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MBCFHEDH_01483 2.5e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MBCFHEDH_01484 1.3e-126 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MBCFHEDH_01485 7.3e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
MBCFHEDH_01486 5e-101 ybhL S Belongs to the BI1 family
MBCFHEDH_01487 3.2e-12 ycdA S Domain of unknown function (DUF4352)
MBCFHEDH_01488 3.1e-242 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MBCFHEDH_01489 4.1e-90 K transcriptional regulator
MBCFHEDH_01490 3.5e-36 yneF S UPF0154 protein
MBCFHEDH_01491 3.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MBCFHEDH_01492 6.2e-182 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MBCFHEDH_01493 8.1e-96 XK27_09740 S Phosphoesterase
MBCFHEDH_01494 2.7e-85 ykuL S CBS domain
MBCFHEDH_01495 2.9e-126 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
MBCFHEDH_01496 3.4e-121 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MBCFHEDH_01497 1.2e-95 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MBCFHEDH_01498 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MBCFHEDH_01499 1.8e-257 trkH P Cation transport protein
MBCFHEDH_01500 9.3e-245 trkA P Potassium transporter peripheral membrane component
MBCFHEDH_01501 1.8e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MBCFHEDH_01502 5.6e-87 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MBCFHEDH_01503 1.7e-90 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
MBCFHEDH_01504 2.7e-155 K sequence-specific DNA binding
MBCFHEDH_01505 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MBCFHEDH_01506 5.4e-53 yhaI L Membrane
MBCFHEDH_01507 2.9e-241 S Domain of unknown function (DUF4173)
MBCFHEDH_01508 1.5e-94 ureI S AmiS/UreI family transporter
MBCFHEDH_01509 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
MBCFHEDH_01510 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
MBCFHEDH_01511 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MBCFHEDH_01512 6.6e-78 ureE O enzyme active site formation
MBCFHEDH_01513 3.8e-128 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MBCFHEDH_01514 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MBCFHEDH_01515 7e-158 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MBCFHEDH_01516 7.9e-177 cbiM P PDGLE domain
MBCFHEDH_01517 1.7e-134 P cobalt transport protein
MBCFHEDH_01518 1.7e-128 cbiO P ABC transporter
MBCFHEDH_01519 5.3e-137 ET ABC transporter substrate-binding protein
MBCFHEDH_01520 7.8e-163 metQ M Belongs to the NlpA lipoprotein family
MBCFHEDH_01521 2.5e-261 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
MBCFHEDH_01522 1.1e-184 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MBCFHEDH_01523 1.2e-99 metI P ABC transporter (Permease
MBCFHEDH_01524 2.5e-209 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
MBCFHEDH_01525 3.5e-157 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
MBCFHEDH_01526 6.7e-93 S UPF0397 protein
MBCFHEDH_01527 2.6e-305 ykoD P abc transporter atp-binding protein
MBCFHEDH_01528 3.2e-147 cbiQ P cobalt transport
MBCFHEDH_01529 3.7e-117 ktrA P COG0569 K transport systems, NAD-binding component
MBCFHEDH_01530 4e-235 P COG0168 Trk-type K transport systems, membrane components
MBCFHEDH_01531 3.5e-126 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
MBCFHEDH_01532 1.2e-89 yceD K metal-binding, possibly nucleic acid-binding protein
MBCFHEDH_01533 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MBCFHEDH_01534 3.3e-278 T PhoQ Sensor
MBCFHEDH_01535 3e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MBCFHEDH_01536 2.4e-212 dnaB L Replication initiation and membrane attachment
MBCFHEDH_01537 4.4e-166 dnaI L Primosomal protein DnaI
MBCFHEDH_01538 9.7e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MBCFHEDH_01539 7.7e-112
MBCFHEDH_01540 6.2e-230 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MBCFHEDH_01541 2.5e-62 manO S protein conserved in bacteria
MBCFHEDH_01542 4e-167 manN G PTS system mannose fructose sorbose family IID component
MBCFHEDH_01543 1.2e-114 manM G pts system
MBCFHEDH_01544 4.9e-174 manL 2.7.1.191 G pts system
MBCFHEDH_01545 5.9e-67 manO S Protein conserved in bacteria
MBCFHEDH_01546 5.9e-158 manN G PTS system mannose fructose sorbose family IID component
MBCFHEDH_01547 5.7e-133 manY G pts system
MBCFHEDH_01548 6.2e-169 manL 2.7.1.191 G pts system
MBCFHEDH_01549 3.2e-138 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
MBCFHEDH_01550 7.8e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
MBCFHEDH_01551 1.6e-247 pbuO S permease
MBCFHEDH_01552 2.7e-76 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
MBCFHEDH_01553 2.6e-86 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
MBCFHEDH_01554 5.9e-185 brpA K Transcriptional
MBCFHEDH_01555 1.1e-80 rimP S Required for maturation of 30S ribosomal subunits
MBCFHEDH_01556 2.4e-196 nusA K Participates in both transcription termination and antitermination
MBCFHEDH_01557 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
MBCFHEDH_01558 8e-42 ylxQ J ribosomal protein
MBCFHEDH_01559 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MBCFHEDH_01560 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MBCFHEDH_01561 2.2e-99 yvdD 3.2.2.10 S Belongs to the LOG family
MBCFHEDH_01562 3.3e-188 femA 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
MBCFHEDH_01563 2.1e-266 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MBCFHEDH_01564 5.2e-279 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
MBCFHEDH_01565 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
MBCFHEDH_01566 1.1e-200 metB 2.5.1.48, 4.4.1.8 E cystathionine
MBCFHEDH_01567 1.3e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MBCFHEDH_01568 2.6e-264 L Transposase
MBCFHEDH_01569 7.1e-306 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
MBCFHEDH_01570 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
MBCFHEDH_01571 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MBCFHEDH_01572 3.7e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MBCFHEDH_01573 9.2e-72 ylbF S Belongs to the UPF0342 family
MBCFHEDH_01574 5.4e-46 ylbG S UPF0298 protein
MBCFHEDH_01575 8.5e-210 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
MBCFHEDH_01576 1.2e-144 livH E Belongs to the binding-protein-dependent transport system permease family
MBCFHEDH_01577 4.9e-139 livM E Belongs to the binding-protein-dependent transport system permease family
MBCFHEDH_01578 4e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
MBCFHEDH_01579 5.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
MBCFHEDH_01580 2.5e-110 acuB S CBS domain
MBCFHEDH_01581 2e-166 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MBCFHEDH_01582 2.9e-108 yvyE 3.4.13.9 S YigZ family
MBCFHEDH_01583 5.7e-239 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MBCFHEDH_01584 1.2e-99 comFC K competence protein
MBCFHEDH_01585 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MBCFHEDH_01586 2e-224 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MBCFHEDH_01587 3.4e-14 rpmH J Ribosomal protein L34
MBCFHEDH_01588 1.2e-97 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
MBCFHEDH_01589 2.4e-99 K Transcriptional regulator
MBCFHEDH_01590 3e-150 jag S RNA-binding protein
MBCFHEDH_01591 9.7e-147 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MBCFHEDH_01592 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MBCFHEDH_01593 2.3e-262 argH 4.3.2.1 E Argininosuccinate lyase
MBCFHEDH_01594 1.7e-229 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MBCFHEDH_01595 4.7e-129 fasA KT Response regulator of the LytR AlgR family
MBCFHEDH_01596 4.7e-225 fasC T protein histidine kinase activity
MBCFHEDH_01597 9.3e-210 hpk9 2.7.13.3 T protein histidine kinase activity
MBCFHEDH_01598 1.5e-150 hpk9 2.7.13.3 T protein histidine kinase activity
MBCFHEDH_01599 1.1e-229 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
MBCFHEDH_01600 1.6e-271 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MBCFHEDH_01601 0.0 amiA E ABC transporter, substrate-binding protein, family 5
MBCFHEDH_01602 5.3e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MBCFHEDH_01603 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MBCFHEDH_01604 1.2e-50 S Protein of unknown function (DUF3397)
MBCFHEDH_01605 1e-87 cah 4.2.1.1 P Reversible hydration of carbon dioxide
MBCFHEDH_01606 1.6e-126 WQ51_05710 S Mitochondrial biogenesis AIM24
MBCFHEDH_01607 1.5e-225 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MBCFHEDH_01608 1e-73 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
MBCFHEDH_01609 3.2e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
MBCFHEDH_01610 8.2e-108 XK27_09620 S FMN reductase (NADPH) activity
MBCFHEDH_01611 7.9e-230 XK27_09615 C reductase
MBCFHEDH_01612 1.6e-140 fnt P Formate nitrite transporter
MBCFHEDH_01613 6.7e-96 XK27_08585 S Psort location CytoplasmicMembrane, score
MBCFHEDH_01614 9.1e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MBCFHEDH_01615 5.7e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MBCFHEDH_01616 9.1e-116 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
MBCFHEDH_01617 5.9e-94 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MBCFHEDH_01618 7.4e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MBCFHEDH_01619 5.3e-58 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MBCFHEDH_01620 1.4e-128 S HAD hydrolase, family IA, variant
MBCFHEDH_01621 3.5e-157 rrmA 2.1.1.187 Q methyltransferase
MBCFHEDH_01625 5.1e-90 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MBCFHEDH_01626 6.6e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MBCFHEDH_01627 8.3e-37 yeeD O sulfur carrier activity
MBCFHEDH_01628 6.1e-188 yeeE S Sulphur transport
MBCFHEDH_01629 1.9e-112 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MBCFHEDH_01630 1.3e-08 S NTF2 fold immunity protein
MBCFHEDH_01631 2.3e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MBCFHEDH_01632 2e-08 XK27_10305 S Domain of unknown function (DUF4651)
MBCFHEDH_01633 7e-203 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
MBCFHEDH_01634 5.2e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MBCFHEDH_01635 4e-100 S CAAX amino terminal protease family protein
MBCFHEDH_01637 3.2e-105 V CAAX protease self-immunity
MBCFHEDH_01638 1.5e-26 lanR K sequence-specific DNA binding
MBCFHEDH_01639 7.5e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MBCFHEDH_01640 1.5e-175 ytxK 2.1.1.72 L DNA methylase
MBCFHEDH_01641 1.2e-12 comGF U Putative Competence protein ComGF
MBCFHEDH_01642 1.3e-70 comGF U Competence protein ComGF
MBCFHEDH_01643 1.8e-15 NU Type II secretory pathway pseudopilin
MBCFHEDH_01644 6e-68 cglD NU Competence protein
MBCFHEDH_01645 2.2e-43 comGC U Required for transformation and DNA binding
MBCFHEDH_01646 1.7e-143 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MBCFHEDH_01647 4.2e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MBCFHEDH_01648 1e-68 S cog cog4699
MBCFHEDH_01649 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MBCFHEDH_01650 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MBCFHEDH_01651 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MBCFHEDH_01652 5.5e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MBCFHEDH_01653 3.9e-195 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MBCFHEDH_01654 2.2e-76 ilvN 2.2.1.6 E Acetolactate synthase
MBCFHEDH_01655 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
MBCFHEDH_01656 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
MBCFHEDH_01660 4.2e-303 yloV S kinase related to dihydroxyacetone kinase
MBCFHEDH_01661 1.4e-57 asp S cog cog1302
MBCFHEDH_01662 1.9e-223 norN V Mate efflux family protein
MBCFHEDH_01663 1e-276 thrC 4.2.3.1 E Threonine synthase
MBCFHEDH_01666 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MBCFHEDH_01667 0.0 pepO 3.4.24.71 O Peptidase family M13
MBCFHEDH_01668 6.8e-256 treC 3.2.1.93 GH13 G COG0366 Glycosidases
MBCFHEDH_01669 5.1e-96 ywlG S Belongs to the UPF0340 family
MBCFHEDH_01672 1.3e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
MBCFHEDH_01674 4.3e-239 6.3.2.2 H gamma-glutamylcysteine synthetase
MBCFHEDH_01675 4.4e-62 rplQ J ribosomal protein l17
MBCFHEDH_01676 4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MBCFHEDH_01677 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MBCFHEDH_01678 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MBCFHEDH_01679 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MBCFHEDH_01680 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MBCFHEDH_01681 2.5e-115 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MBCFHEDH_01682 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MBCFHEDH_01683 5.7e-58 rplO J binds to the 23S rRNA
MBCFHEDH_01684 1.9e-23 rpmD J ribosomal protein l30
MBCFHEDH_01685 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MBCFHEDH_01686 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MBCFHEDH_01687 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MBCFHEDH_01688 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MBCFHEDH_01689 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MBCFHEDH_01690 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MBCFHEDH_01691 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MBCFHEDH_01692 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MBCFHEDH_01693 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MBCFHEDH_01694 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
MBCFHEDH_01695 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MBCFHEDH_01696 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MBCFHEDH_01697 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MBCFHEDH_01698 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MBCFHEDH_01699 6.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MBCFHEDH_01700 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MBCFHEDH_01701 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
MBCFHEDH_01702 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MBCFHEDH_01703 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
MBCFHEDH_01704 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MBCFHEDH_01705 0.0 XK27_09800 I Acyltransferase
MBCFHEDH_01706 2.8e-35 XK27_09805 S MORN repeat protein
MBCFHEDH_01707 2.6e-79 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MBCFHEDH_01708 1e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MBCFHEDH_01709 5e-90 adk 2.7.4.3 F topology modulation protein
MBCFHEDH_01710 5.1e-82 S Short repeat of unknown function (DUF308)
MBCFHEDH_01711 5e-90 K sequence-specific DNA binding
MBCFHEDH_01712 1.5e-156 L Replication initiation factor
MBCFHEDH_01713 1.9e-18 S Domain of unknown function (DUF3173)
MBCFHEDH_01714 1e-212 int L Belongs to the 'phage' integrase family
MBCFHEDH_01716 7.5e-236 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
MBCFHEDH_01717 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MBCFHEDH_01718 6.3e-44 yrzL S Belongs to the UPF0297 family
MBCFHEDH_01719 1.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MBCFHEDH_01720 3.2e-44 yrzB S Belongs to the UPF0473 family
MBCFHEDH_01721 5.8e-289 ccs S the current gene model (or a revised gene model) may contain a frame shift
MBCFHEDH_01722 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
MBCFHEDH_01723 7.5e-14
MBCFHEDH_01724 1.2e-85 XK27_10930 K acetyltransferase
MBCFHEDH_01725 1e-113 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MBCFHEDH_01726 1.3e-120 yaaA S Belongs to the UPF0246 family
MBCFHEDH_01727 9.3e-167 XK27_01785 S cog cog1284
MBCFHEDH_01728 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MBCFHEDH_01730 1.2e-238 hisS 6.1.1.21 J histidyl-tRNA synthetase
MBCFHEDH_01731 3.1e-89 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
MBCFHEDH_01732 7.1e-42 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
MBCFHEDH_01733 4.7e-08 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
MBCFHEDH_01734 4.3e-219 metE 2.1.1.14 E Methionine synthase
MBCFHEDH_01735 3.4e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MBCFHEDH_01736 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MBCFHEDH_01741 7e-115 nudL L hydrolase
MBCFHEDH_01742 6.3e-54 K transcriptional regulator, PadR family
MBCFHEDH_01743 8.6e-62 XK27_06920 S Protein of unknown function (DUF1700)
MBCFHEDH_01744 1.8e-105 S Putative adhesin
MBCFHEDH_01745 7.3e-160 XK27_06930 V domain protein
MBCFHEDH_01746 1.6e-94 XK27_06935 K transcriptional regulator
MBCFHEDH_01747 3.8e-52 ypaA M Membrane
MBCFHEDH_01748 1.1e-10
MBCFHEDH_01749 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MBCFHEDH_01750 1.8e-47 veg S Biofilm formation stimulator VEG
MBCFHEDH_01751 6.5e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MBCFHEDH_01752 2.2e-73 rplI J binds to the 23S rRNA
MBCFHEDH_01753 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MBCFHEDH_01754 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MBCFHEDH_01755 7.8e-98 yvbG U UPF0056 membrane protein
MBCFHEDH_01756 1.2e-218 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MBCFHEDH_01757 2.3e-304 S Bacterial membrane protein, YfhO
MBCFHEDH_01758 9.3e-63 isaA GH23 M Immunodominant staphylococcal antigen A
MBCFHEDH_01759 5.9e-71 lytE M LysM domain protein
MBCFHEDH_01760 4.4e-133 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MBCFHEDH_01761 1.2e-149 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MBCFHEDH_01762 3.5e-149 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MBCFHEDH_01763 2.6e-89 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MBCFHEDH_01764 1e-127 S sequence-specific DNA binding
MBCFHEDH_01765 9.2e-234 ymfH S Peptidase M16
MBCFHEDH_01766 2.5e-228 ymfF S Peptidase M16
MBCFHEDH_01767 1.9e-57 yaaA S S4 domain protein YaaA
MBCFHEDH_01768 3.7e-199 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MBCFHEDH_01769 1.1e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MBCFHEDH_01770 7.2e-189 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
MBCFHEDH_01771 9.3e-153 yvjA S membrane
MBCFHEDH_01772 1.1e-305 ybiT S abc transporter atp-binding protein
MBCFHEDH_01773 0.0 XK27_10405 S Bacterial membrane protein YfhO
MBCFHEDH_01777 2.2e-117 yoaK S Protein of unknown function (DUF1275)
MBCFHEDH_01778 2e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MBCFHEDH_01779 1.5e-201 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
MBCFHEDH_01780 3.2e-133 parB K Belongs to the ParB family
MBCFHEDH_01781 8.5e-254 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MBCFHEDH_01782 8e-197 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MBCFHEDH_01783 3.2e-29 yyzM S Protein conserved in bacteria
MBCFHEDH_01784 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MBCFHEDH_01785 5.2e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MBCFHEDH_01786 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MBCFHEDH_01787 2.2e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MBCFHEDH_01788 8.7e-60 divIC D Septum formation initiator
MBCFHEDH_01790 2.3e-232 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
MBCFHEDH_01791 1.3e-227 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MBCFHEDH_01792 2.9e-96 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MBCFHEDH_01793 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MBCFHEDH_01794 1.7e-68 3.4.21.110 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MBCFHEDH_01796 2.9e-10
MBCFHEDH_01797 6.5e-186 XK27_10075 S abc transporter atp-binding protein
MBCFHEDH_01798 0.0 V abc transporter atp-binding protein
MBCFHEDH_01799 1.4e-296 V abc transporter atp-binding protein
MBCFHEDH_01800 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
MBCFHEDH_01802 1.7e-279 S Protein of unknown function (DUF3114)
MBCFHEDH_01803 6.5e-99 2.3.1.128 K Acetyltransferase GNAT Family
MBCFHEDH_01804 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MBCFHEDH_01805 9.2e-283 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
MBCFHEDH_01806 1.8e-180 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
MBCFHEDH_01807 5.8e-187 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MBCFHEDH_01808 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MBCFHEDH_01809 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
MBCFHEDH_01810 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MBCFHEDH_01811 4.7e-185 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
MBCFHEDH_01812 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MBCFHEDH_01813 9.9e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MBCFHEDH_01816 3.1e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MBCFHEDH_01817 9.7e-170 vraS 2.7.13.3 T Histidine kinase
MBCFHEDH_01818 1.9e-116 yvqF S Membrane
MBCFHEDH_01819 7.9e-100 kcsA P Ion transport protein
MBCFHEDH_01820 2.6e-293 prkC 2.7.11.1 KLT serine threonine protein kinase
MBCFHEDH_01821 3.8e-134 stp 3.1.3.16 T phosphatase
MBCFHEDH_01822 8.1e-241 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MBCFHEDH_01823 9.9e-169 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MBCFHEDH_01824 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MBCFHEDH_01825 3.6e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
MBCFHEDH_01826 8.8e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MBCFHEDH_01827 3.2e-195 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MBCFHEDH_01828 3.1e-142 XK27_02985 S overlaps another CDS with the same product name
MBCFHEDH_01829 2.2e-145 supH S overlaps another CDS with the same product name
MBCFHEDH_01830 2.8e-61 yvoA_1 K Transcriptional
MBCFHEDH_01831 1.8e-119 skfE V abc transporter atp-binding protein
MBCFHEDH_01832 1.4e-128 V Psort location CytoplasmicMembrane, score
MBCFHEDH_01833 3.1e-170 oppF P Belongs to the ABC transporter superfamily
MBCFHEDH_01834 9.3e-203 oppD P Belongs to the ABC transporter superfamily
MBCFHEDH_01835 2.9e-165 amiD P ABC transporter (Permease
MBCFHEDH_01836 8.1e-274 amiC P ABC transporter (Permease
MBCFHEDH_01837 2.7e-311 amiA E ABC transporter, substrate-binding protein, family 5
MBCFHEDH_01838 0.0 amiA E ABC transporter, substrate-binding protein, family 5
MBCFHEDH_01839 2.2e-174 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MBCFHEDH_01840 1e-170 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
MBCFHEDH_01841 3.4e-152 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MBCFHEDH_01842 3e-119 yjbM 2.7.6.5 S Gtp pyrophosphokinase
MBCFHEDH_01843 2.4e-101 yjbK S Adenylate cyclase
MBCFHEDH_01844 8.7e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MBCFHEDH_01845 1.4e-206 iscS 2.8.1.7 E Cysteine desulfurase
MBCFHEDH_01846 8.2e-60 XK27_04120 S Putative amino acid metabolism
MBCFHEDH_01847 1.9e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MBCFHEDH_01848 1e-130 puuD T peptidase C26
MBCFHEDH_01849 2.6e-118 radC E Belongs to the UPF0758 family
MBCFHEDH_01850 0.0 rgpF M Rhamnan synthesis protein F
MBCFHEDH_01851 1.6e-183 rgpEc GT2 M Glycosyl transferase family 2
MBCFHEDH_01852 8.1e-224 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MBCFHEDH_01853 1.2e-141 rgpC GM Transport permease protein
MBCFHEDH_01854 1.1e-170 rgpB GT2 M Glycosyltransferase, group 2 family protein
MBCFHEDH_01855 6.6e-215 rgpA GT4 M Domain of unknown function (DUF1972)
MBCFHEDH_01856 2.9e-141 S Predicted membrane protein (DUF2142)
MBCFHEDH_01857 5.4e-128 2.7.8.12 M transferase activity, transferring glycosyl groups
MBCFHEDH_01858 7.3e-215 amrA S polysaccharide biosynthetic process
MBCFHEDH_01859 1.1e-45 XK27_09090 S Uncharacterized conserved protein (DUF2304)
MBCFHEDH_01860 4.2e-124 ycbB S Glycosyl transferase family 2
MBCFHEDH_01861 1.7e-159 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MBCFHEDH_01862 8.9e-240
MBCFHEDH_01863 4.4e-169 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
MBCFHEDH_01864 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
MBCFHEDH_01865 4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MBCFHEDH_01866 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MBCFHEDH_01867 6.4e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MBCFHEDH_01868 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MBCFHEDH_01869 7.9e-135 gltS ET Belongs to the bacterial solute-binding protein 3 family
MBCFHEDH_01870 4.1e-206 arcT 2.6.1.1 E Aminotransferase
MBCFHEDH_01871 1.2e-135 ET Belongs to the bacterial solute-binding protein 3 family
MBCFHEDH_01872 2.5e-136 ET ABC transporter
MBCFHEDH_01873 1.8e-78 mutT 3.6.1.55 F Nudix family
MBCFHEDH_01874 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MBCFHEDH_01876 1.4e-162 S CAAX amino terminal protease family protein
MBCFHEDH_01877 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
MBCFHEDH_01878 1.1e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
MBCFHEDH_01879 1.7e-17 XK27_00735
MBCFHEDH_01880 0.0 3.5.1.28 NU amidase activity
MBCFHEDH_01881 0.0 lpdA 1.8.1.4 C Dehydrogenase
MBCFHEDH_01882 1.1e-211 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MBCFHEDH_01883 1.4e-181 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MBCFHEDH_01884 4.3e-183 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
MBCFHEDH_01885 2e-201 hpk9 2.7.13.3 T protein histidine kinase activity
MBCFHEDH_01886 1.2e-225 2.7.13.3 T protein histidine kinase activity
MBCFHEDH_01887 0.0 S the current gene model (or a revised gene model) may contain a frame shift
MBCFHEDH_01888 8.2e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MBCFHEDH_01889 4.1e-121 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MBCFHEDH_01890 1.1e-212 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MBCFHEDH_01891 1.2e-244 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
MBCFHEDH_01892 6.5e-182 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
MBCFHEDH_01893 5.3e-153 rssA S Phospholipase, patatin family
MBCFHEDH_01894 2e-101 estA E Lysophospholipase L1 and related esterases
MBCFHEDH_01895 4e-279 S unusual protein kinase
MBCFHEDH_01896 4.1e-38 S granule-associated protein
MBCFHEDH_01897 9.8e-285 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MBCFHEDH_01898 1.8e-196 S hmm pf01594
MBCFHEDH_01899 2.8e-108 G Belongs to the phosphoglycerate mutase family
MBCFHEDH_01900 5.4e-107 G Belongs to the phosphoglycerate mutase family
MBCFHEDH_01901 1.4e-107 pgm G Belongs to the phosphoglycerate mutase family
MBCFHEDH_01902 4.8e-143 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
MBCFHEDH_01904 5e-185 wbbI M transferase activity, transferring glycosyl groups
MBCFHEDH_01905 3.1e-173 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
MBCFHEDH_01906 4.8e-215 glf 5.4.99.9 M UDP-galactopyranose mutase
MBCFHEDH_01907 1.1e-157 S Acyltransferase family
MBCFHEDH_01908 2e-250 epsU S Polysaccharide biosynthesis protein
MBCFHEDH_01909 1.3e-173
MBCFHEDH_01910 2.8e-153 M Glycosyltransferase like family 2
MBCFHEDH_01911 1.7e-163 M Glycosyltransferase, group 2 family protein
MBCFHEDH_01912 6.8e-121 Z012_10770 M Domain of unknown function (DUF1919)
MBCFHEDH_01913 4.2e-214 wcoF M Glycosyltransferase, group 1 family protein
MBCFHEDH_01914 8.2e-221 rgpAc GT4 M group 1 family protein
MBCFHEDH_01915 8e-252 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
MBCFHEDH_01916 5.9e-116 cpsD D COG0489 ATPases involved in chromosome partitioning
MBCFHEDH_01917 1.2e-110 cps4C M biosynthesis protein
MBCFHEDH_01918 6.8e-133 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
MBCFHEDH_01919 1.2e-250 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
MBCFHEDH_01920 4.9e-128 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
MBCFHEDH_01921 8.7e-133 yfeJ 6.3.5.2 F glutamine amidotransferase
MBCFHEDH_01922 5.2e-173 clcA_2 P Chloride transporter, ClC family
MBCFHEDH_01923 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MBCFHEDH_01924 4.2e-87 S Protein of unknown function (DUF1697)
MBCFHEDH_01925 2.3e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
MBCFHEDH_01926 4.7e-120 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MBCFHEDH_01927 3.6e-252 V Glucan-binding protein C
MBCFHEDH_01928 3.8e-227 V Glucan-binding protein C
MBCFHEDH_01929 3.3e-106 ung2 3.2.2.27 L Uracil-DNA glycosylase
MBCFHEDH_01930 2.5e-269 pepV 3.5.1.18 E Dipeptidase
MBCFHEDH_01931 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
MBCFHEDH_01932 1.6e-91 yybC
MBCFHEDH_01933 1.5e-77 XK27_03610 K Gnat family
MBCFHEDH_01934 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MBCFHEDH_01935 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MBCFHEDH_01936 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MBCFHEDH_01937 4.3e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MBCFHEDH_01938 5.5e-17 M LysM domain
MBCFHEDH_01939 9.6e-86 ebsA S Family of unknown function (DUF5322)
MBCFHEDH_01940 3.2e-228 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MBCFHEDH_01941 9.2e-84 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
MBCFHEDH_01942 3.7e-79 hmpT S cog cog4720
MBCFHEDH_01943 1.2e-135 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
MBCFHEDH_01944 3.8e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MBCFHEDH_01945 8e-189 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MBCFHEDH_01947 1.8e-307 dnaK O Heat shock 70 kDa protein
MBCFHEDH_01948 5.7e-73 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MBCFHEDH_01949 9.2e-184 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MBCFHEDH_01950 1.7e-97 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
MBCFHEDH_01951 1.7e-140 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
MBCFHEDH_01952 2.6e-129 ais G Phosphoglycerate mutase
MBCFHEDH_01953 9.6e-242 XK27_08635 S UPF0210 protein
MBCFHEDH_01954 2.3e-38 gcvR T UPF0237 protein
MBCFHEDH_01955 3.3e-233 capA M Bacterial capsule synthesis protein
MBCFHEDH_01956 8.6e-148 srtB 3.4.22.70 S Sortase family
MBCFHEDH_01958 1.5e-29 K Helix-turn-helix domain
MBCFHEDH_01959 1.3e-17
MBCFHEDH_01960 1.5e-15 S Protein of unknown function (DUF1211)
MBCFHEDH_01962 9e-52 frnE Q DSBA-like thioredoxin domain
MBCFHEDH_01964 1.3e-123 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MBCFHEDH_01965 1.7e-16 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MBCFHEDH_01966 5.5e-47 trxA O Belongs to the thioredoxin family
MBCFHEDH_01968 2.2e-98 M1-798 K Rhodanese Homology Domain
MBCFHEDH_01969 1.2e-27 int2 L Belongs to the 'phage' integrase family
MBCFHEDH_01970 1.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
MBCFHEDH_01971 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MBCFHEDH_01972 5.1e-22 K Transcriptional
MBCFHEDH_01974 1.2e-149 degV S DegV family
MBCFHEDH_01975 6e-91 yacP S RNA-binding protein containing a PIN domain
MBCFHEDH_01976 1.1e-133 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MBCFHEDH_01978 1.2e-65 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MBCFHEDH_01979 9e-256 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MBCFHEDH_01980 2.5e-112 cysE 2.3.1.30 E serine acetyltransferase
MBCFHEDH_01981 1.5e-138 S SseB protein N-terminal domain
MBCFHEDH_01982 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MBCFHEDH_01983 6.9e-226 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MBCFHEDH_01984 7.9e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MBCFHEDH_01985 0.0 clpC O Belongs to the ClpA ClpB family
MBCFHEDH_01986 1.8e-75 ctsR K Belongs to the CtsR family
MBCFHEDH_01987 1.6e-82 S Putative small multi-drug export protein
MBCFHEDH_01988 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MBCFHEDH_01989 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
MBCFHEDH_01990 4.2e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
MBCFHEDH_01991 8.6e-287 ahpF O alkyl hydroperoxide reductase
MBCFHEDH_01993 4.7e-94 S reductase
MBCFHEDH_01994 3.9e-72 badR K Transcriptional regulator, marr family
MBCFHEDH_01995 1.2e-35 XK27_02060 S Transglycosylase associated protein
MBCFHEDH_01996 1.1e-236 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
MBCFHEDH_01997 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MBCFHEDH_02002 1.9e-07
MBCFHEDH_02005 2.6e-10
MBCFHEDH_02008 0.0 M domain protein
MBCFHEDH_02009 0.0 zmpB M signal peptide protein, YSIRK family
MBCFHEDH_02010 0.0 GM domain, Protein
MBCFHEDH_02011 1.3e-218 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MBCFHEDH_02012 0.0 sbcC L ATPase involved in DNA repair
MBCFHEDH_02013 0.0 M family 8
MBCFHEDH_02014 6.1e-211 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
MBCFHEDH_02015 2.9e-290 asp1 S Accessory Sec system protein Asp1
MBCFHEDH_02016 8.3e-290 asp2 3.4.11.5 S Accessory Sec system protein Asp2
MBCFHEDH_02017 1.7e-78 asp3 S Accessory Sec system protein Asp3
MBCFHEDH_02018 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MBCFHEDH_02019 1.5e-280 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MBCFHEDH_02020 2e-242 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
MBCFHEDH_02021 2.6e-17 S Accessory secretory protein Sec Asp4
MBCFHEDH_02022 3.6e-16 S Accessory secretory protein Sec, Asp5
MBCFHEDH_02023 4e-184 nss M transferase activity, transferring glycosyl groups
MBCFHEDH_02024 0.0 sraP UW Hep Hag repeat protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)