ORF_ID e_value Gene_name EC_number CAZy COGs Description
AKEMDJAB_00002 3.4e-131 3.5.1.28 M domain protein
AKEMDJAB_00003 1.7e-10
AKEMDJAB_00004 4.1e-188 XK27_10075 S abc transporter atp-binding protein
AKEMDJAB_00005 0.0 V abc transporter atp-binding protein
AKEMDJAB_00006 5.2e-296 V abc transporter atp-binding protein
AKEMDJAB_00007 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
AKEMDJAB_00009 1.2e-283 S Protein of unknown function (DUF3114)
AKEMDJAB_00010 1.8e-101 2.3.1.128 K Acetyltransferase GNAT Family
AKEMDJAB_00011 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
AKEMDJAB_00012 9.2e-283 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
AKEMDJAB_00013 1.8e-180 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
AKEMDJAB_00014 5.8e-187 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AKEMDJAB_00015 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AKEMDJAB_00016 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
AKEMDJAB_00017 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
AKEMDJAB_00018 2.3e-187 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
AKEMDJAB_00019 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
AKEMDJAB_00020 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AKEMDJAB_00023 1.8e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
AKEMDJAB_00024 1.9e-170 vraS 2.7.13.3 T Histidine kinase
AKEMDJAB_00025 5e-117 yvqF S Membrane
AKEMDJAB_00026 4.1e-104 kcsA P Ion transport protein
AKEMDJAB_00027 2.7e-290 prkC 2.7.11.1 KLT serine threonine protein kinase
AKEMDJAB_00028 1.5e-135 stp 3.1.3.16 T phosphatase
AKEMDJAB_00029 1.9e-242 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AKEMDJAB_00030 1.1e-170 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AKEMDJAB_00031 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AKEMDJAB_00032 3.6e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
AKEMDJAB_00033 8.8e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
AKEMDJAB_00034 2.1e-191 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AKEMDJAB_00035 3.7e-143 XK27_02985 S overlaps another CDS with the same product name
AKEMDJAB_00036 4.2e-144 supH S overlaps another CDS with the same product name
AKEMDJAB_00037 5.6e-62 yvoA_1 K Transcriptional
AKEMDJAB_00038 7e-119 skfE V abc transporter atp-binding protein
AKEMDJAB_00039 5.3e-115 V ATPase activity
AKEMDJAB_00040 1.7e-79 hmpT S cog cog4720
AKEMDJAB_00041 3.1e-136 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
AKEMDJAB_00042 3.8e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
AKEMDJAB_00043 1.8e-188 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
AKEMDJAB_00044 4.9e-103 thiJ-2 3.5.1.124 S DJ-1/PfpI family
AKEMDJAB_00045 6e-303 dnaK O Heat shock 70 kDa protein
AKEMDJAB_00046 8.2e-64 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AKEMDJAB_00047 3.7e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
AKEMDJAB_00048 3.6e-100 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
AKEMDJAB_00049 1.4e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
AKEMDJAB_00050 1.2e-131 ais G Phosphoglycerate mutase
AKEMDJAB_00051 2.3e-243 XK27_08635 S UPF0210 protein
AKEMDJAB_00052 6.1e-39 gcvR T UPF0237 protein
AKEMDJAB_00053 2.5e-233 capA M Bacterial capsule synthesis protein
AKEMDJAB_00054 2e-149 srtB 3.4.22.70 S Sortase family
AKEMDJAB_00056 1.5e-29 K Helix-turn-helix domain
AKEMDJAB_00057 7.6e-18
AKEMDJAB_00058 4.5e-55 cadX K transcriptional regulator, ArsR family
AKEMDJAB_00059 1.5e-101 cadD P cadmium resistance
AKEMDJAB_00060 1.7e-221 L transposase IS116 IS110 IS902 family
AKEMDJAB_00061 0.0 ctpC 3.6.3.10, 3.6.3.4 P p-ATPase superfamily P-type ATPase copper transporter
AKEMDJAB_00062 2.6e-40
AKEMDJAB_00063 1.6e-105 L Transposase
AKEMDJAB_00064 1e-31 yegS 2.7.1.107 I lipid kinase activity
AKEMDJAB_00065 2.4e-54 S membrane protein of uknown function UCP014873
AKEMDJAB_00066 1.6e-32 int L DNA integration
AKEMDJAB_00067 4.9e-82
AKEMDJAB_00068 3.4e-28
AKEMDJAB_00069 2.3e-110 fic D Fic/DOC family
AKEMDJAB_00070 1.8e-136 S Belongs to the short-chain dehydrogenases reductases (SDR) family
AKEMDJAB_00071 8.2e-63 rmeD K Transcriptional regulator
AKEMDJAB_00072 3.9e-43 K DNA-binding helix-turn-helix protein
AKEMDJAB_00074 2.6e-36
AKEMDJAB_00075 8.3e-193 L Replication initiation factor
AKEMDJAB_00076 1.6e-39 L Helix-turn-helix domain
AKEMDJAB_00077 1.2e-222 int2 L Phage integrase family
AKEMDJAB_00078 1.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
AKEMDJAB_00079 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AKEMDJAB_00080 5.1e-22 K Transcriptional
AKEMDJAB_00082 3.2e-150 degV S DegV family
AKEMDJAB_00083 2.7e-91 yacP S RNA-binding protein containing a PIN domain
AKEMDJAB_00084 3.7e-134 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AKEMDJAB_00086 1.4e-66 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AKEMDJAB_00088 1.1e-234 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
AKEMDJAB_00090 2.5e-112 cysE 2.3.1.30 E serine acetyltransferase
AKEMDJAB_00091 4.7e-140 S SseB protein N-terminal domain
AKEMDJAB_00092 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
AKEMDJAB_00093 1.8e-226 dacA 3.4.16.4 M Belongs to the peptidase S11 family
AKEMDJAB_00094 3.5e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
AKEMDJAB_00095 0.0 clpC O Belongs to the ClpA ClpB family
AKEMDJAB_00096 2e-74 ctsR K Belongs to the CtsR family
AKEMDJAB_00097 4.6e-82 S Putative small multi-drug export protein
AKEMDJAB_00098 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AKEMDJAB_00099 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
AKEMDJAB_00100 1.1e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
AKEMDJAB_00101 3.5e-288 ahpF O alkyl hydroperoxide reductase
AKEMDJAB_00103 3.6e-94 S reductase
AKEMDJAB_00104 4.4e-71 badR K Transcriptional regulator, marr family
AKEMDJAB_00105 1.2e-35 XK27_02060 S Transglycosylase associated protein
AKEMDJAB_00106 2.5e-236 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
AKEMDJAB_00107 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AKEMDJAB_00108 3.6e-49 qacC P COG2076 Membrane transporters of cations and cationic drugs
AKEMDJAB_00109 1e-75 K Transcriptional
AKEMDJAB_00110 7.2e-75
AKEMDJAB_00111 7e-228 L Replication initiation factor
AKEMDJAB_00112 3.4e-67
AKEMDJAB_00113 3.5e-28 S Domain of unknown function (DUF3173)
AKEMDJAB_00114 4.2e-198 L Belongs to the 'phage' integrase family
AKEMDJAB_00119 1.9e-07
AKEMDJAB_00122 2.6e-10
AKEMDJAB_00125 0.0 prtA 3.2.1.23 O Belongs to the peptidase S8 family
AKEMDJAB_00126 5.2e-78 K Acetyltransferase (GNAT) domain
AKEMDJAB_00127 5.6e-141 S ABC-2 family transporter protein
AKEMDJAB_00128 2.6e-141 S ABC-2 family transporter protein
AKEMDJAB_00129 1e-184 S abc transporter atp-binding protein
AKEMDJAB_00130 9.7e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
AKEMDJAB_00131 4.5e-189 desK 2.7.13.3 T Histidine kinase
AKEMDJAB_00132 1.5e-132 yvfS V ABC-2 type transporter
AKEMDJAB_00133 2.5e-158 XK27_09825 V 'abc transporter, ATP-binding protein
AKEMDJAB_00136 1.3e-163 yocS S Transporter
AKEMDJAB_00137 4.4e-82 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
AKEMDJAB_00138 2.2e-115 yvfS V Transporter
AKEMDJAB_00139 9e-156 XK27_09825 V abc transporter atp-binding protein
AKEMDJAB_00140 4.1e-15 liaI KT membrane
AKEMDJAB_00141 4.4e-30 liaI KT membrane
AKEMDJAB_00142 6.1e-93 XK27_05000 S metal cluster binding
AKEMDJAB_00143 0.0 V ABC transporter (permease)
AKEMDJAB_00144 1.6e-132 macB2 V ABC transporter, ATP-binding protein
AKEMDJAB_00145 4.1e-149 T Histidine kinase
AKEMDJAB_00146 5.4e-124 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AKEMDJAB_00147 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
AKEMDJAB_00148 3.8e-224 pbuX F xanthine permease
AKEMDJAB_00149 3e-271 V (ABC) transporter
AKEMDJAB_00150 1.4e-145 K sequence-specific DNA binding
AKEMDJAB_00151 3e-243 norM V Multidrug efflux pump
AKEMDJAB_00153 1.7e-179 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AKEMDJAB_00154 1.4e-229 brnQ E Component of the transport system for branched-chain amino acids
AKEMDJAB_00155 2.7e-182 manA 5.3.1.8 G mannose-6-phosphate isomerase
AKEMDJAB_00156 1.2e-29 S Protein of unknown function (DUF3290)
AKEMDJAB_00157 5e-108 S Protein of unknown function (DUF421)
AKEMDJAB_00158 1.1e-16 csbD S CsbD-like
AKEMDJAB_00159 5.2e-114 S Carbohydrate-binding domain-containing protein Cthe_2159
AKEMDJAB_00160 2.6e-50 XK27_01300 S ASCH
AKEMDJAB_00161 7.2e-216 yfnA E amino acid
AKEMDJAB_00162 0.0 S dextransucrase activity
AKEMDJAB_00163 5.8e-59 M Putative cell wall binding repeat
AKEMDJAB_00164 2.4e-225 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
AKEMDJAB_00165 3.4e-14 rpmH J Ribosomal protein L34
AKEMDJAB_00166 1.6e-97 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
AKEMDJAB_00167 7.6e-98 K Transcriptional regulator
AKEMDJAB_00168 2.9e-169 jag S RNA-binding protein
AKEMDJAB_00169 1.7e-140 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AKEMDJAB_00170 1.6e-52 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
AKEMDJAB_00171 2.1e-263 argH 4.3.2.1 E Argininosuccinate lyase
AKEMDJAB_00172 1.7e-229 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
AKEMDJAB_00173 4.7e-129 fasA KT Response regulator of the LytR AlgR family
AKEMDJAB_00174 8.9e-224 fasC 2.7.13.3 T protein histidine kinase activity
AKEMDJAB_00175 1.9e-207 hpk9 2.7.13.3 T protein histidine kinase activity
AKEMDJAB_00176 1.2e-150 hpk9 2.7.13.3 T protein histidine kinase activity
AKEMDJAB_00177 1.4e-229 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
AKEMDJAB_00178 8.7e-281 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AKEMDJAB_00179 0.0 amiA E ABC transporter, substrate-binding protein, family 5
AKEMDJAB_00180 1.4e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
AKEMDJAB_00181 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AKEMDJAB_00182 1.2e-50 S Protein of unknown function (DUF3397)
AKEMDJAB_00183 9.2e-89 cah 4.2.1.1 P Reversible hydration of carbon dioxide
AKEMDJAB_00184 1.6e-126 WQ51_05710 S Mitochondrial biogenesis AIM24
AKEMDJAB_00185 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AKEMDJAB_00186 3.3e-73 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
AKEMDJAB_00187 1.3e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
AKEMDJAB_00188 3.1e-107 XK27_09620 S FMN reductase (NADPH) activity
AKEMDJAB_00189 2.1e-230 XK27_09615 C reductase
AKEMDJAB_00190 2.4e-139 fnt P Formate nitrite transporter
AKEMDJAB_00191 1.8e-96 XK27_08585 S Psort location CytoplasmicMembrane, score
AKEMDJAB_00192 5.7e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
AKEMDJAB_00193 1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
AKEMDJAB_00194 5.7e-118 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
AKEMDJAB_00195 2.2e-96 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AKEMDJAB_00196 3e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
AKEMDJAB_00197 1.5e-57 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
AKEMDJAB_00198 1.4e-128 S HAD hydrolase, family IA, variant
AKEMDJAB_00199 5e-156 rrmA 2.1.1.187 Q methyltransferase
AKEMDJAB_00203 5.1e-90 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
AKEMDJAB_00204 1.9e-65 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
AKEMDJAB_00205 8.3e-37 yeeD O sulfur carrier activity
AKEMDJAB_00206 4.3e-189 yeeE S Sulphur transport
AKEMDJAB_00207 5.1e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
AKEMDJAB_00208 1.2e-09 S NTF2 fold immunity protein
AKEMDJAB_00209 2.3e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
AKEMDJAB_00210 2.7e-08 XK27_10305 S Domain of unknown function (DUF4651)
AKEMDJAB_00211 1.4e-203 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
AKEMDJAB_00212 4.8e-129 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AKEMDJAB_00216 4.1e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
AKEMDJAB_00217 1.4e-59 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AKEMDJAB_00218 1.8e-136 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
AKEMDJAB_00219 2.4e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AKEMDJAB_00220 2.3e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AKEMDJAB_00221 6.7e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
AKEMDJAB_00222 7.1e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AKEMDJAB_00223 5.5e-118 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
AKEMDJAB_00224 1.3e-179 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AKEMDJAB_00225 8.5e-193 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AKEMDJAB_00226 9.2e-60 XK27_08085
AKEMDJAB_00227 4.7e-147 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
AKEMDJAB_00228 9.3e-138 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
AKEMDJAB_00229 1.3e-116 ylfI S tigr01906
AKEMDJAB_00230 6.7e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
AKEMDJAB_00231 4.5e-140 fat 3.1.2.21 I Acyl-ACP thioesterase
AKEMDJAB_00232 9.4e-214 hemN H Involved in the biosynthesis of porphyrin-containing compound
AKEMDJAB_00233 6.4e-30 KT response to antibiotic
AKEMDJAB_00235 3.6e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
AKEMDJAB_00236 2.7e-111 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
AKEMDJAB_00237 3.2e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AKEMDJAB_00238 1.1e-253 S phospholipase Carboxylesterase
AKEMDJAB_00239 2.3e-193 yurR 1.4.5.1 E oxidoreductase
AKEMDJAB_00240 1.3e-143 zupT P Mediates zinc uptake. May also transport other divalent cations
AKEMDJAB_00241 1.2e-143 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AKEMDJAB_00242 1.3e-120 trmK 2.1.1.217 S SAM-dependent methyltransferase
AKEMDJAB_00243 1.3e-64 gtrA S GtrA-like protein
AKEMDJAB_00244 8.2e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AKEMDJAB_00245 1.1e-162 ybbR S Protein conserved in bacteria
AKEMDJAB_00246 6.7e-148 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AKEMDJAB_00247 2e-252 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
AKEMDJAB_00248 9.6e-149 cobQ S glutamine amidotransferase
AKEMDJAB_00249 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AKEMDJAB_00250 2e-132 pip 1.11.1.10 S Alpha beta hydrolase
AKEMDJAB_00251 1.6e-39 MA20_06245 S yiaA/B two helix domain
AKEMDJAB_00252 0.0 uup S abc transporter atp-binding protein
AKEMDJAB_00253 3.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
AKEMDJAB_00254 1.8e-177 yfmL 3.6.4.13 L DEAD DEAH box helicase
AKEMDJAB_00255 1.4e-225 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
AKEMDJAB_00256 2.7e-153 XK27_05675 S Esterase
AKEMDJAB_00257 1.8e-161 XK27_05670 S Putative esterase
AKEMDJAB_00258 6.6e-50 ywrO S general stress protein
AKEMDJAB_00259 8.3e-30 K sequence-specific DNA binding
AKEMDJAB_00260 3.4e-78 3.4.21.89 S RDD family
AKEMDJAB_00261 3.8e-78 mutT 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
AKEMDJAB_00262 1.2e-151 S Protein of unknown function DUF262
AKEMDJAB_00263 2e-202 S Protein of unknown function DUF262
AKEMDJAB_00264 1.8e-101 L Integrase
AKEMDJAB_00265 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
AKEMDJAB_00266 2.6e-147 sdaAA 4.3.1.17 E L-serine dehydratase
AKEMDJAB_00267 1.2e-120 sdaAB 4.3.1.17 E L-serine dehydratase
AKEMDJAB_00268 2e-129 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
AKEMDJAB_00269 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
AKEMDJAB_00270 1.2e-36 P (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AKEMDJAB_00271 1.3e-260 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AKEMDJAB_00272 5.2e-87 pat 2.3.1.183 M acetyltransferase
AKEMDJAB_00273 1e-274 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AKEMDJAB_00274 3.8e-119 alkD L Dna alkylation repair
AKEMDJAB_00275 6.2e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AKEMDJAB_00276 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AKEMDJAB_00277 7.9e-123 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
AKEMDJAB_00278 0.0 smc D Required for chromosome condensation and partitioning
AKEMDJAB_00279 6.3e-91 S Protein of unknown function (DUF3278)
AKEMDJAB_00280 1.1e-22 WQ51_00220 K Helix-turn-helix domain
AKEMDJAB_00281 8.7e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AKEMDJAB_00282 9.2e-92 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AKEMDJAB_00283 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
AKEMDJAB_00285 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
AKEMDJAB_00286 1.1e-234 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
AKEMDJAB_00288 6.3e-85 S ECF-type riboflavin transporter, S component
AKEMDJAB_00289 1.1e-153 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
AKEMDJAB_00290 1.5e-81 XK27_01265 S ECF-type riboflavin transporter, S component
AKEMDJAB_00291 5.6e-294 yfmM S abc transporter atp-binding protein
AKEMDJAB_00292 1.4e-256 noxE P NADH oxidase
AKEMDJAB_00293 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AKEMDJAB_00294 2.3e-84 yxjI S LURP-one-related
AKEMDJAB_00295 3e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
AKEMDJAB_00296 3e-119 yrrM 2.1.1.104 S O-Methyltransferase
AKEMDJAB_00297 9.1e-215 oxlT P COG0477 Permeases of the major facilitator superfamily
AKEMDJAB_00298 0.0 pepF E oligoendopeptidase F
AKEMDJAB_00299 5e-168 coiA 3.6.4.12 S Competence protein
AKEMDJAB_00300 2.4e-49 L COG1943 Transposase and inactivated derivatives
AKEMDJAB_00301 5.6e-267 2.7.13.3, 2.7.7.7, 5.4.99.21 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AKEMDJAB_00302 1.2e-103 S CAAX amino terminal protease family protein
AKEMDJAB_00303 4.7e-168 K transcriptional regulator (lysR family)
AKEMDJAB_00304 9.9e-160 S reductase
AKEMDJAB_00306 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AKEMDJAB_00310 2.4e-187 phoH T phosphate starvation-inducible protein PhoH
AKEMDJAB_00311 1e-128 sip M LysM domain protein
AKEMDJAB_00312 3.7e-34 yozE S Belongs to the UPF0346 family
AKEMDJAB_00313 1.3e-159 cvfB S Protein conserved in bacteria
AKEMDJAB_00314 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
AKEMDJAB_00315 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
AKEMDJAB_00316 1.6e-211 sptS 2.7.13.3 T Histidine kinase
AKEMDJAB_00317 6e-115 T response regulator
AKEMDJAB_00318 1.3e-111 2.7.6.5 S Region found in RelA / SpoT proteins
AKEMDJAB_00319 9.1e-110 K Acetyltransferase (GNAT) family
AKEMDJAB_00320 0.0 lmrA2 V abc transporter atp-binding protein
AKEMDJAB_00321 1.8e-310 lmrA1 V abc transporter atp-binding protein
AKEMDJAB_00322 3e-75 K DNA-binding transcription factor activity
AKEMDJAB_00323 4.6e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
AKEMDJAB_00324 1.3e-280 S Psort location CytoplasmicMembrane, score
AKEMDJAB_00325 1.4e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
AKEMDJAB_00326 6.5e-212 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
AKEMDJAB_00327 3.1e-128 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
AKEMDJAB_00328 3.8e-26 U response to pH
AKEMDJAB_00329 7.8e-102 ygaC J Belongs to the UPF0374 family
AKEMDJAB_00330 8.3e-137 recX 2.4.1.337 GT4 S Regulatory protein RecX
AKEMDJAB_00331 1e-246 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AKEMDJAB_00332 5.2e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
AKEMDJAB_00333 8.2e-257 lysC 2.7.2.4 E Belongs to the aspartokinase family
AKEMDJAB_00334 1.3e-116 S HAD hydrolase, family IA, variant 3
AKEMDJAB_00335 2.1e-140 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
AKEMDJAB_00336 5.2e-72 marR K Transcriptional regulator, MarR family
AKEMDJAB_00337 1.1e-170 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AKEMDJAB_00338 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
AKEMDJAB_00339 9.9e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
AKEMDJAB_00340 3.3e-161 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
AKEMDJAB_00341 1.1e-125 IQ reductase
AKEMDJAB_00342 1.3e-232 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
AKEMDJAB_00343 1.6e-53 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
AKEMDJAB_00344 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
AKEMDJAB_00345 8.3e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
AKEMDJAB_00346 1e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AKEMDJAB_00347 5.1e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
AKEMDJAB_00348 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
AKEMDJAB_00349 7.1e-207 rny D Endoribonuclease that initiates mRNA decay
AKEMDJAB_00350 2.3e-112 fruR K transcriptional
AKEMDJAB_00351 7.6e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
AKEMDJAB_00352 0.0 fruA 2.7.1.202 G phosphotransferase system
AKEMDJAB_00353 5.3e-256 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AKEMDJAB_00354 4.6e-222 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
AKEMDJAB_00356 1.8e-212 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
AKEMDJAB_00357 6.3e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AKEMDJAB_00358 5.3e-289 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
AKEMDJAB_00359 4.1e-253 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
AKEMDJAB_00360 2.1e-83 2.3.1.128 K acetyltransferase
AKEMDJAB_00361 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
AKEMDJAB_00362 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
AKEMDJAB_00363 7e-127 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AKEMDJAB_00364 5e-63 WQ51_03320 S cog cog4835
AKEMDJAB_00365 2.8e-146 XK27_08360 S EDD domain protein, DegV family
AKEMDJAB_00366 2.5e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
AKEMDJAB_00367 7.1e-220 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AKEMDJAB_00368 0.0 yfmR S abc transporter atp-binding protein
AKEMDJAB_00369 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
AKEMDJAB_00370 1.2e-135 agrA KT response regulator
AKEMDJAB_00371 4e-07
AKEMDJAB_00372 2e-132 agrA KT phosphorelay signal transduction system
AKEMDJAB_00373 6.6e-227 2.7.13.3 T GHKL domain
AKEMDJAB_00374 5.7e-14
AKEMDJAB_00375 0.0 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
AKEMDJAB_00376 2e-138 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
AKEMDJAB_00377 3.3e-222 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
AKEMDJAB_00378 5e-182 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AKEMDJAB_00379 8.6e-218 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AKEMDJAB_00380 8.4e-123 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
AKEMDJAB_00381 1e-204 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
AKEMDJAB_00382 1.1e-129 yxkH G deacetylase
AKEMDJAB_00383 2.6e-236 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
AKEMDJAB_00384 5.9e-152 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
AKEMDJAB_00385 2.8e-149 rarD S Transporter
AKEMDJAB_00386 1.8e-17 T peptidase
AKEMDJAB_00387 3e-14 coiA 3.6.4.12 S Competence protein
AKEMDJAB_00388 3.8e-102 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AKEMDJAB_00389 4.9e-09 rimL 2.3.1.128, 5.2.1.8 J Acetyltransferase (GNAT) domain
AKEMDJAB_00390 5.6e-109
AKEMDJAB_00392 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
AKEMDJAB_00393 3.4e-182 femA 2.3.2.10, 2.3.2.16 V FemAB family
AKEMDJAB_00394 1.9e-10 glnQ 3.6.3.21 E abc transporter atp-binding protein
AKEMDJAB_00395 3.8e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AKEMDJAB_00396 3.2e-220 vicK 2.7.13.3 T Histidine kinase
AKEMDJAB_00397 2.3e-153 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
AKEMDJAB_00398 1.5e-56 S Protein of unknown function (DUF454)
AKEMDJAB_00399 6.7e-226 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
AKEMDJAB_00400 7.8e-146 yidA S hydrolases of the HAD superfamily
AKEMDJAB_00401 1.9e-145 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
AKEMDJAB_00402 4.5e-67 ywiB S Domain of unknown function (DUF1934)
AKEMDJAB_00403 0.0 pacL 3.6.3.8 P cation transport ATPase
AKEMDJAB_00404 1.9e-130 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
AKEMDJAB_00405 2.3e-153 yjjH S Calcineurin-like phosphoesterase
AKEMDJAB_00406 3.5e-205 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AKEMDJAB_00407 5.7e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AKEMDJAB_00408 5.5e-124 ftsE D cell division ATP-binding protein FtsE
AKEMDJAB_00409 7.3e-164 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
AKEMDJAB_00410 4.3e-91 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
AKEMDJAB_00411 4e-175 yubA S permease
AKEMDJAB_00412 9.2e-223 G COG0457 FOG TPR repeat
AKEMDJAB_00413 3.3e-95 lepB 3.4.21.89 U Belongs to the peptidase S26 family
AKEMDJAB_00414 0.0 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
AKEMDJAB_00415 5.9e-230 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
AKEMDJAB_00416 8.6e-87 ebsA S Family of unknown function (DUF5322)
AKEMDJAB_00417 9.4e-17 M LysM domain
AKEMDJAB_00418 3.6e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
AKEMDJAB_00419 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AKEMDJAB_00420 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
AKEMDJAB_00421 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AKEMDJAB_00422 1.9e-83 XK27_03610 K Gnat family
AKEMDJAB_00423 3.9e-90 yybC
AKEMDJAB_00424 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
AKEMDJAB_00425 4.5e-274 pepV 3.5.1.18 E Dipeptidase
AKEMDJAB_00426 2.1e-108 ung2 3.2.2.27 L Uracil-DNA glycosylase
AKEMDJAB_00427 2.9e-38 L High confidence in function and specificity
AKEMDJAB_00428 3.1e-145 L High confidence in function and specificity
AKEMDJAB_00429 9.2e-253 V Glucan-binding protein C
AKEMDJAB_00430 4.7e-120 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AKEMDJAB_00431 1e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
AKEMDJAB_00432 8.8e-85 S Protein of unknown function (DUF1697)
AKEMDJAB_00433 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AKEMDJAB_00434 6.4e-51 S LemA family
AKEMDJAB_00435 4.1e-162 clcA_2 P chloride
AKEMDJAB_00436 2.4e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
AKEMDJAB_00437 4.9e-128 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
AKEMDJAB_00438 5.2e-249 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
AKEMDJAB_00439 6.8e-133 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
AKEMDJAB_00440 1.2e-110 cps4C M biosynthesis protein
AKEMDJAB_00441 5.9e-116 cpsD D COG0489 ATPases involved in chromosome partitioning
AKEMDJAB_00442 2.1e-252 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
AKEMDJAB_00443 4.1e-220 rgpAc GT4 M group 1 family protein
AKEMDJAB_00444 5.2e-212 wcoF M Glycosyltransferase, group 1 family protein
AKEMDJAB_00445 6.4e-84 Z012_10770 M Domain of unknown function (DUF1919)
AKEMDJAB_00446 7.6e-172 M Glycosyltransferase, group 2 family protein
AKEMDJAB_00447 6e-148 M Glycosyltransferase like family 2
AKEMDJAB_00448 4e-175
AKEMDJAB_00449 8.3e-244 epsU S Polysaccharide biosynthesis protein
AKEMDJAB_00450 4.8e-215 glf 5.4.99.9 M UDP-galactopyranose mutase
AKEMDJAB_00451 1.4e-173 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
AKEMDJAB_00452 2.2e-185 wbbI M transferase activity, transferring glycosyl groups
AKEMDJAB_00454 9.4e-139 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
AKEMDJAB_00455 4.8e-108 pgm G Belongs to the phosphoglycerate mutase family
AKEMDJAB_00456 1.8e-107 G Belongs to the phosphoglycerate mutase family
AKEMDJAB_00457 6.4e-105 G Belongs to the phosphoglycerate mutase family
AKEMDJAB_00458 2.2e-194 S hmm pf01594
AKEMDJAB_00459 2.9e-284 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AKEMDJAB_00460 4.1e-38 S granule-associated protein
AKEMDJAB_00461 5.2e-279 S unusual protein kinase
AKEMDJAB_00462 3.6e-98 estA E Lysophospholipase L1 and related esterases
AKEMDJAB_00463 6.5e-151 rssA S Phospholipase, patatin family
AKEMDJAB_00464 6.8e-171 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
AKEMDJAB_00465 5.8e-247 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
AKEMDJAB_00466 5.4e-212 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AKEMDJAB_00467 1.2e-120 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AKEMDJAB_00468 4.8e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
AKEMDJAB_00469 0.0 S the current gene model (or a revised gene model) may contain a frame shift
AKEMDJAB_00470 1.2e-225 2.7.13.3 T protein histidine kinase activity
AKEMDJAB_00471 3.5e-201 hpk9 2.7.13.3 T protein histidine kinase activity
AKEMDJAB_00472 1.5e-183 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
AKEMDJAB_00473 6.4e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
AKEMDJAB_00474 6e-207 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
AKEMDJAB_00475 0.0 lpdA 1.8.1.4 C Dehydrogenase
AKEMDJAB_00476 0.0 3.5.1.28 NU amidase activity
AKEMDJAB_00477 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
AKEMDJAB_00478 1.1e-145 ycdO P periplasmic lipoprotein involved in iron transport
AKEMDJAB_00479 2e-230 ycdB P peroxidase
AKEMDJAB_00480 7.5e-292 ywbL P COG0672 High-affinity Fe2 Pb2 permease
AKEMDJAB_00481 3.2e-119 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AKEMDJAB_00482 3e-24 tatA U protein secretion
AKEMDJAB_00483 4.7e-213 msmX P Belongs to the ABC transporter superfamily
AKEMDJAB_00484 2.2e-151 malG P ABC transporter (Permease
AKEMDJAB_00485 1.4e-248 malF P ABC transporter (Permease
AKEMDJAB_00486 3.9e-229 malX G ABC transporter
AKEMDJAB_00487 2.1e-156 malR K Transcriptional regulator
AKEMDJAB_00488 2.8e-298 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
AKEMDJAB_00489 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
AKEMDJAB_00490 1.5e-38
AKEMDJAB_00491 1.8e-184 lplA 6.3.1.20 H Lipoate-protein ligase
AKEMDJAB_00492 1.1e-192 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
AKEMDJAB_00493 0.0 pepN 3.4.11.2 E aminopeptidase
AKEMDJAB_00494 3.2e-113 phoU P Plays a role in the regulation of phosphate uptake
AKEMDJAB_00495 7.3e-138 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
AKEMDJAB_00496 5.7e-149 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
AKEMDJAB_00497 9.1e-156 pstA P phosphate transport system permease
AKEMDJAB_00498 1.4e-156 pstC P probably responsible for the translocation of the substrate across the membrane
AKEMDJAB_00499 1.1e-156 pstS P phosphate
AKEMDJAB_00500 1e-251 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
AKEMDJAB_00501 5.9e-143 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
AKEMDJAB_00502 1e-44 yktA S Belongs to the UPF0223 family
AKEMDJAB_00503 7.2e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
AKEMDJAB_00504 1.5e-169 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
AKEMDJAB_00505 3e-148 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AKEMDJAB_00506 1.8e-243 XK27_04775 S hemerythrin HHE cation binding domain
AKEMDJAB_00507 2.3e-34 M1-755 P Hemerythrin HHE cation binding domain protein
AKEMDJAB_00508 3.7e-111 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
AKEMDJAB_00509 5.5e-86 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AKEMDJAB_00510 1.1e-136 S haloacid dehalogenase-like hydrolase
AKEMDJAB_00511 8.6e-240 metY 2.5.1.49 E o-acetylhomoserine
AKEMDJAB_00512 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
AKEMDJAB_00513 9e-240 agcS E (Alanine) symporter
AKEMDJAB_00514 2e-242 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AKEMDJAB_00515 4.6e-169 bglC K Transcriptional regulator
AKEMDJAB_00516 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
AKEMDJAB_00517 6.4e-82 yecS P ABC transporter (Permease
AKEMDJAB_00518 3.9e-148 yckB ET Belongs to the bacterial solute-binding protein 3 family
AKEMDJAB_00519 5.5e-235 nylA 3.5.1.4 J Belongs to the amidase family
AKEMDJAB_00520 4.4e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AKEMDJAB_00521 1e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
AKEMDJAB_00522 6.5e-103
AKEMDJAB_00523 1.3e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
AKEMDJAB_00524 2.9e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
AKEMDJAB_00525 8.8e-93 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
AKEMDJAB_00526 5.7e-133 S TraX protein
AKEMDJAB_00527 1.5e-308 FbpA K RNA-binding protein homologous to eukaryotic snRNP
AKEMDJAB_00528 3e-263 S Psort location CytoplasmicMembrane, score
AKEMDJAB_00529 4e-232 dinF V Mate efflux family protein
AKEMDJAB_00530 4.1e-178 yclQ P ABC-type enterochelin transport system, periplasmic component
AKEMDJAB_00531 0.0 V Type III restriction enzyme, res subunit
AKEMDJAB_00532 3.8e-111 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
AKEMDJAB_00533 7e-242 S the current gene model (or a revised gene model) may contain a frame shift
AKEMDJAB_00534 3.4e-186 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
AKEMDJAB_00535 4.2e-195 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
AKEMDJAB_00536 1.3e-157 czcD P cation diffusion facilitator family transporter
AKEMDJAB_00537 2.7e-94 K Transcriptional regulator, TetR family
AKEMDJAB_00538 7.6e-69 S Protein of unknown function with HXXEE motif
AKEMDJAB_00539 7e-11
AKEMDJAB_00540 2.3e-29 pnuC H Nicotinamide mononucleotide transporter
AKEMDJAB_00541 1.7e-81 tnp L DDE domain
AKEMDJAB_00542 9.1e-147 cbiO2 P ABC transporter, ATP-binding protein
AKEMDJAB_00543 3.5e-157 P abc transporter atp-binding protein
AKEMDJAB_00544 3.7e-132 cbiQ P cobalt transport
AKEMDJAB_00545 6.3e-92 2.7.7.65 T Psort location CytoplasmicMembrane, score
AKEMDJAB_00546 2.8e-140 S Phenazine biosynthesis protein
AKEMDJAB_00547 7.5e-267 proWX P ABC transporter
AKEMDJAB_00548 8.3e-123 proV E abc transporter atp-binding protein
AKEMDJAB_00549 8.1e-150 C alcohol dehydrogenase
AKEMDJAB_00550 6.7e-131 S SnoaL-like domain
AKEMDJAB_00551 8.3e-65 mgrA K Transcriptional regulator, MarR family
AKEMDJAB_00552 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
AKEMDJAB_00553 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
AKEMDJAB_00556 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
AKEMDJAB_00558 1.1e-136 IQ Acetoin reductase
AKEMDJAB_00559 2.2e-45 pspE P Rhodanese-like protein
AKEMDJAB_00560 9.4e-71 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
AKEMDJAB_00561 2.7e-221 XK27_05470 E Methionine synthase
AKEMDJAB_00562 3.6e-257 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AKEMDJAB_00563 1.2e-239 T PhoQ Sensor
AKEMDJAB_00564 2.2e-122 KT Transcriptional regulatory protein, C terminal
AKEMDJAB_00565 3.4e-149 S TraX protein
AKEMDJAB_00566 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AKEMDJAB_00567 3.3e-155 dprA LU DNA protecting protein DprA
AKEMDJAB_00568 2.7e-163 GK ROK family
AKEMDJAB_00569 5.3e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AKEMDJAB_00570 9.4e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AKEMDJAB_00571 2e-126 K DNA-binding helix-turn-helix protein
AKEMDJAB_00572 4.3e-89 niaR S small molecule binding protein (contains 3H domain)
AKEMDJAB_00573 2.7e-86
AKEMDJAB_00574 3.8e-274 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AKEMDJAB_00575 2e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AKEMDJAB_00576 2.2e-125 gntR1 K transcriptional
AKEMDJAB_00577 1.3e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
AKEMDJAB_00578 1e-99 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
AKEMDJAB_00579 4.6e-188 adhP 1.1.1.1 C alcohol dehydrogenase
AKEMDJAB_00580 1e-44
AKEMDJAB_00581 2e-269 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AKEMDJAB_00582 2.3e-156 aatB ET ABC transporter substrate-binding protein
AKEMDJAB_00583 4.4e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
AKEMDJAB_00584 1.4e-105 artQ P ABC transporter (Permease
AKEMDJAB_00585 6.6e-59 phnA P Alkylphosphonate utilization operon protein PhnA
AKEMDJAB_00586 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
AKEMDJAB_00587 2.2e-165 cpsY K Transcriptional regulator
AKEMDJAB_00588 9.3e-127 mur1 3.4.17.14, 3.5.1.28 NU muramidase
AKEMDJAB_00589 2.9e-166 yeiH S Membrane
AKEMDJAB_00591 3.4e-09
AKEMDJAB_00592 3.6e-293 adcA P Belongs to the bacterial solute-binding protein 9 family
AKEMDJAB_00593 1e-145 XK27_10720 D peptidase activity
AKEMDJAB_00594 1.6e-276 pepD E Dipeptidase
AKEMDJAB_00595 2.2e-160 whiA K May be required for sporulation
AKEMDJAB_00596 6.2e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
AKEMDJAB_00597 2.2e-162 rapZ S Displays ATPase and GTPase activities
AKEMDJAB_00598 6.5e-134 yejC S cyclic nucleotide-binding protein
AKEMDJAB_00599 3e-204 D nuclear chromosome segregation
AKEMDJAB_00600 1.4e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
AKEMDJAB_00601 1.2e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
AKEMDJAB_00602 8.8e-83 queD 4.1.2.50, 4.2.3.12 H synthase
AKEMDJAB_00603 1.2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AKEMDJAB_00604 2.3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
AKEMDJAB_00605 3.7e-19
AKEMDJAB_00606 8.4e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
AKEMDJAB_00607 4.5e-211 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
AKEMDJAB_00608 1.1e-81 ypmB S Protein conserved in bacteria
AKEMDJAB_00609 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
AKEMDJAB_00610 4.7e-114 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
AKEMDJAB_00611 3.5e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
AKEMDJAB_00612 2.6e-181 yufP S Belongs to the binding-protein-dependent transport system permease family
AKEMDJAB_00613 1.6e-277 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
AKEMDJAB_00614 3.2e-187 tcsA S membrane
AKEMDJAB_00615 2.2e-64 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
AKEMDJAB_00616 1.8e-111 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AKEMDJAB_00617 5e-232 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
AKEMDJAB_00618 1.7e-105 rsmC 2.1.1.172 J Methyltransferase small domain protein
AKEMDJAB_00619 2.1e-171 coaA 2.7.1.33 F Pantothenic acid kinase
AKEMDJAB_00620 2.3e-29 rpsT J Binds directly to 16S ribosomal RNA
AKEMDJAB_00621 2.4e-235 T PhoQ Sensor
AKEMDJAB_00622 2.1e-120 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AKEMDJAB_00623 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
AKEMDJAB_00624 4.3e-113 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
AKEMDJAB_00625 2e-89 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AKEMDJAB_00626 1.3e-91 panT S ECF transporter, substrate-specific component
AKEMDJAB_00627 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
AKEMDJAB_00628 1.5e-239 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AKEMDJAB_00629 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AKEMDJAB_00630 1.2e-235 dltB M Membrane protein involved in D-alanine export
AKEMDJAB_00631 4.2e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AKEMDJAB_00632 0.0 XK27_10035 V abc transporter atp-binding protein
AKEMDJAB_00633 1.1e-290 yfiB1 V abc transporter atp-binding protein
AKEMDJAB_00634 1.2e-98 pvaA M lytic transglycosylase activity
AKEMDJAB_00635 1.9e-178 ndpA S 37-kD nucleoid-associated bacterial protein
AKEMDJAB_00636 2.3e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AKEMDJAB_00637 1.1e-61 XK27_05710 K Acetyltransferase (GNAT) domain
AKEMDJAB_00638 9.2e-99 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
AKEMDJAB_00639 1.5e-144 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
AKEMDJAB_00640 3.6e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AKEMDJAB_00641 4.6e-111 tdk 2.7.1.21 F thymidine kinase
AKEMDJAB_00642 1.2e-183 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AKEMDJAB_00643 9.3e-152 gst O Glutathione S-transferase
AKEMDJAB_00644 2.2e-176 nrnA 3.1.13.3, 3.1.3.7 S domain protein
AKEMDJAB_00645 1.9e-172 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
AKEMDJAB_00646 4.4e-45 rpmE2 J 50S ribosomal protein L31
AKEMDJAB_00647 1.7e-227 mntH P Mn2 and Fe2 transporters of the NRAMP family
AKEMDJAB_00648 7.6e-164 ypuA S secreted protein
AKEMDJAB_00649 9.1e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
AKEMDJAB_00650 9.3e-133 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
AKEMDJAB_00651 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AKEMDJAB_00652 9.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
AKEMDJAB_00653 2e-67 manO S Protein conserved in bacteria
AKEMDJAB_00654 2.7e-163 manN G PTS system mannose fructose sorbose family IID component
AKEMDJAB_00655 4.7e-135 manY G pts system
AKEMDJAB_00656 8.1e-169 manL 2.7.1.191 G pts system
AKEMDJAB_00657 7.1e-138 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
AKEMDJAB_00658 3.5e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
AKEMDJAB_00659 1.6e-247 pbuO S permease
AKEMDJAB_00660 9.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
AKEMDJAB_00661 8.7e-90 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
AKEMDJAB_00662 7.5e-188 brpA K Transcriptional
AKEMDJAB_00663 2.3e-81 rimP S Required for maturation of 30S ribosomal subunits
AKEMDJAB_00664 7.1e-196 nusA K Participates in both transcription termination and antitermination
AKEMDJAB_00665 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
AKEMDJAB_00666 8e-42 ylxQ J ribosomal protein
AKEMDJAB_00667 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AKEMDJAB_00668 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AKEMDJAB_00669 1.7e-99 yvdD 3.2.2.10 S Belongs to the LOG family
AKEMDJAB_00670 1.7e-268 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AKEMDJAB_00671 5.4e-287 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
AKEMDJAB_00672 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
AKEMDJAB_00673 2.6e-200 metB 2.5.1.48, 4.4.1.8 E cystathionine
AKEMDJAB_00674 3e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
AKEMDJAB_00675 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
AKEMDJAB_00676 4.4e-203 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AKEMDJAB_00677 3.5e-225 cinA 3.5.1.42 S Belongs to the CinA family
AKEMDJAB_00678 3e-104 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
AKEMDJAB_00679 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
AKEMDJAB_00681 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AKEMDJAB_00683 5.4e-69 K LytTr DNA-binding domain
AKEMDJAB_00684 7.1e-80 S Protein of unknown function (DUF3021)
AKEMDJAB_00685 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AKEMDJAB_00686 2.4e-54 ymcA 3.6.3.21 S Belongs to the UPF0342 family
AKEMDJAB_00687 3.4e-68 argR K Regulates arginine biosynthesis genes
AKEMDJAB_00688 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
AKEMDJAB_00691 2.1e-12
AKEMDJAB_00692 1.3e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AKEMDJAB_00693 1.5e-33
AKEMDJAB_00694 3.8e-173 1.1.1.169 H Ketopantoate reductase
AKEMDJAB_00695 3e-201 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AKEMDJAB_00696 9.1e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AKEMDJAB_00697 1.9e-239 purD 6.3.4.13 F Belongs to the GARS family
AKEMDJAB_00698 1.6e-20 D Plasmid stabilization system
AKEMDJAB_00699 4.3e-14 XK27_10545
AKEMDJAB_00700 1.9e-155 S CHAP domain
AKEMDJAB_00701 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AKEMDJAB_00702 3.9e-95 comFC S Competence protein
AKEMDJAB_00703 1.4e-248 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AKEMDJAB_00704 2.2e-108 yvyE 3.4.13.9 S YigZ family
AKEMDJAB_00705 6.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
AKEMDJAB_00706 2.3e-111 acuB S CBS domain
AKEMDJAB_00707 1.6e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
AKEMDJAB_00708 1.1e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
AKEMDJAB_00709 4.9e-139 livM E Belongs to the binding-protein-dependent transport system permease family
AKEMDJAB_00710 1.2e-144 livH E Belongs to the binding-protein-dependent transport system permease family
AKEMDJAB_00711 1.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
AKEMDJAB_00712 1.9e-46 ylbG S UPF0298 protein
AKEMDJAB_00713 8.9e-67 ylbF S Belongs to the UPF0342 family
AKEMDJAB_00714 3.7e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
AKEMDJAB_00715 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AKEMDJAB_00716 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
AKEMDJAB_00717 0.0 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
AKEMDJAB_00719 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AKEMDJAB_00720 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
AKEMDJAB_00721 3e-93 cvpA S toxin biosynthetic process
AKEMDJAB_00722 9.3e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AKEMDJAB_00723 1.6e-152 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AKEMDJAB_00724 1.6e-106 lepB 3.4.21.89 U Belongs to the peptidase S26 family
AKEMDJAB_00725 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
AKEMDJAB_00726 2.2e-46 azlD S branched-chain amino acid
AKEMDJAB_00727 2.8e-112 azlC E AzlC protein
AKEMDJAB_00728 1.3e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AKEMDJAB_00729 4.8e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
AKEMDJAB_00730 5.5e-116 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
AKEMDJAB_00731 1.5e-33 ykzG S Belongs to the UPF0356 family
AKEMDJAB_00732 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AKEMDJAB_00733 4.5e-123 L Helix-turn-helix domain
AKEMDJAB_00734 3.2e-145 L Integrase core domain protein
AKEMDJAB_00735 9.5e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AKEMDJAB_00736 1.8e-215 araT 2.6.1.1 E Aminotransferase
AKEMDJAB_00737 7.5e-138 recO L Involved in DNA repair and RecF pathway recombination
AKEMDJAB_00738 1e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
AKEMDJAB_00739 4.8e-30 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
AKEMDJAB_00740 3.4e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
AKEMDJAB_00741 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AKEMDJAB_00742 7.8e-274 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AKEMDJAB_00743 2.5e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
AKEMDJAB_00744 2.4e-98 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AKEMDJAB_00745 9.6e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
AKEMDJAB_00748 1.6e-185 nss M transferase activity, transferring glycosyl groups
AKEMDJAB_00749 3.6e-16 S Accessory secretory protein Sec, Asp5
AKEMDJAB_00750 2.6e-17 S Accessory secretory protein Sec Asp4
AKEMDJAB_00751 1.8e-243 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
AKEMDJAB_00752 8.5e-279 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
AKEMDJAB_00753 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
AKEMDJAB_00754 5e-78 asp3 S Accessory Sec system protein Asp3
AKEMDJAB_00755 6.4e-290 asp2 3.4.11.5 S Accessory Sec system protein Asp2
AKEMDJAB_00756 2.3e-287 asp1 S Accessory Sec system protein Asp1
AKEMDJAB_00757 9.5e-212 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
AKEMDJAB_00758 0.0 M family 8
AKEMDJAB_00759 0.0 M domain protein
AKEMDJAB_00760 1.9e-276 bipA S protein secretion
AKEMDJAB_00761 0.0 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
AKEMDJAB_00768 3.2e-183 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AKEMDJAB_00769 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AKEMDJAB_00770 6.5e-34 nrdH O Glutaredoxin
AKEMDJAB_00771 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AKEMDJAB_00772 6.9e-209 citZ 2.3.3.1 C Belongs to the citrate synthase family
AKEMDJAB_00773 8.5e-218 icd 1.1.1.42 C Isocitrate dehydrogenase
AKEMDJAB_00774 3e-38 ptsH G phosphocarrier protein Hpr
AKEMDJAB_00775 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AKEMDJAB_00776 6.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
AKEMDJAB_00777 0.0 pflB 2.3.1.54 C formate acetyltransferase'
AKEMDJAB_00778 7.3e-203 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AKEMDJAB_00779 2.1e-35
AKEMDJAB_00780 5.7e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
AKEMDJAB_00781 1.4e-162 yxeN P ABC transporter (Permease
AKEMDJAB_00782 6.1e-129 tcyN 3.6.3.21 E abc transporter atp-binding protein
AKEMDJAB_00783 5e-10 S Protein of unknown function (DUF4059)
AKEMDJAB_00784 2.1e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
AKEMDJAB_00785 9.6e-92 rsmD 2.1.1.171 L Methyltransferase
AKEMDJAB_00786 1.7e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AKEMDJAB_00787 3.2e-187 ylbL T Belongs to the peptidase S16 family
AKEMDJAB_00788 5.4e-183 yhcC S radical SAM protein
AKEMDJAB_00789 3.6e-94 ytqB 2.1.1.176 J (SAM)-dependent
AKEMDJAB_00791 0.0 yjcE P NhaP-type Na H and K H antiporters
AKEMDJAB_00792 1.1e-141 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
AKEMDJAB_00793 3.2e-237 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
AKEMDJAB_00794 6.2e-09 MU outer membrane autotransporter barrel domain protein
AKEMDJAB_00795 1.5e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AKEMDJAB_00797 9e-75 XK27_03180 T universal stress protein
AKEMDJAB_00798 3.4e-238 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
AKEMDJAB_00799 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AKEMDJAB_00800 4.4e-100 pncA Q isochorismatase
AKEMDJAB_00801 5.4e-291 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AKEMDJAB_00802 3.1e-41 tagE 2.4.1.52 GT4 M transferase activity, transferring glycosyl groups
AKEMDJAB_00803 5.3e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AKEMDJAB_00804 7.7e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
AKEMDJAB_00805 2.3e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AKEMDJAB_00807 1.6e-282 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AKEMDJAB_00808 1.6e-46 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIB subunit
AKEMDJAB_00809 2.9e-279 celR 2.7.1.194, 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
AKEMDJAB_00810 1.7e-40 celC 2.7.1.196, 2.7.1.205 G Phosphotransferase system cellobiose-specific component IIA
AKEMDJAB_00811 4.7e-56
AKEMDJAB_00812 5.3e-216 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AKEMDJAB_00813 2.7e-64
AKEMDJAB_00814 5.3e-151 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
AKEMDJAB_00815 5.1e-98 yqeG S hydrolase of the HAD superfamily
AKEMDJAB_00816 4.1e-214 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
AKEMDJAB_00817 3.8e-48 yhbY J RNA-binding protein
AKEMDJAB_00818 3.8e-116 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AKEMDJAB_00819 3.7e-105 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
AKEMDJAB_00820 3e-87 entB 3.5.1.19 Q Isochorismatase family
AKEMDJAB_00821 7.7e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
AKEMDJAB_00822 8.4e-139 yqeM Q Methyltransferase domain protein
AKEMDJAB_00823 1.4e-195 ylbM S Belongs to the UPF0348 family
AKEMDJAB_00824 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
AKEMDJAB_00825 7.7e-11
AKEMDJAB_00826 1.5e-50
AKEMDJAB_00829 8.6e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
AKEMDJAB_00830 1.1e-130 ecsA V abc transporter atp-binding protein
AKEMDJAB_00831 1.6e-175 ecsB U Bacterial ABC transporter protein EcsB
AKEMDJAB_00832 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
AKEMDJAB_00833 9e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
AKEMDJAB_00835 1.6e-213 ytfP S Flavoprotein
AKEMDJAB_00836 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
AKEMDJAB_00837 9.6e-64 XK27_02560 S cog cog2151
AKEMDJAB_00838 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
AKEMDJAB_00839 2.7e-103 dnaQ 2.7.7.7 L DNA polymerase III
AKEMDJAB_00840 5.5e-72 K transcriptional regulator, MerR family
AKEMDJAB_00841 0.0 V ABC transporter (Permease
AKEMDJAB_00842 1.2e-123 V abc transporter atp-binding protein
AKEMDJAB_00844 7.8e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AKEMDJAB_00845 5e-50
AKEMDJAB_00846 2.2e-45
AKEMDJAB_00847 0.0 ctpE P E1-E2 ATPase
AKEMDJAB_00848 1.2e-59
AKEMDJAB_00849 1.5e-40 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase type II
AKEMDJAB_00850 1.4e-256 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AKEMDJAB_00851 2.3e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
AKEMDJAB_00852 6.6e-179 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AKEMDJAB_00853 2.7e-132 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
AKEMDJAB_00854 1.4e-99 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
AKEMDJAB_00855 8.4e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
AKEMDJAB_00856 1.7e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
AKEMDJAB_00857 5e-162 EGP Major facilitator Superfamily
AKEMDJAB_00858 6.1e-73 copY K negative regulation of transcription, DNA-templated
AKEMDJAB_00859 0.0 copA 3.6.3.54 P P-type ATPase
AKEMDJAB_00860 2.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
AKEMDJAB_00861 1.5e-34 K Transcriptional regulator C-terminal region
AKEMDJAB_00862 2.2e-83 V ABC transporter
AKEMDJAB_00863 5.6e-56
AKEMDJAB_00864 3e-190 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
AKEMDJAB_00865 8.6e-114 papP P ABC transporter (Permease
AKEMDJAB_00866 5.1e-106 P ABC transporter (Permease
AKEMDJAB_00867 3.4e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
AKEMDJAB_00868 9.7e-155 cjaA ET ABC transporter substrate-binding protein
AKEMDJAB_00872 3.5e-255 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
AKEMDJAB_00873 1.1e-116 ywaF S Integral membrane protein (intg_mem_TP0381)
AKEMDJAB_00875 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AKEMDJAB_00876 3.7e-197 yjbB G Permeases of the major facilitator superfamily
AKEMDJAB_00877 3.4e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
AKEMDJAB_00878 3.1e-96 thiT S Thiamine transporter
AKEMDJAB_00879 9.6e-62 yjqA S Bacterial PH domain
AKEMDJAB_00880 7.6e-150 corA P CorA-like protein
AKEMDJAB_00881 3.4e-254 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
AKEMDJAB_00882 1e-41 yazA L endonuclease containing a URI domain
AKEMDJAB_00883 4.6e-140 yabB 2.1.1.223 L Methyltransferase
AKEMDJAB_00884 7.4e-148 nodB3 G Polysaccharide deacetylase
AKEMDJAB_00885 3.7e-142 plsC 2.3.1.51 I Acyltransferase
AKEMDJAB_00886 1.7e-88 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
AKEMDJAB_00887 0.0 comEC S Competence protein ComEC
AKEMDJAB_00888 1e-229 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AKEMDJAB_00889 5.9e-97 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
AKEMDJAB_00890 1.9e-231 ytoI K transcriptional regulator containing CBS domains
AKEMDJAB_00891 1.1e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
AKEMDJAB_00892 3.2e-159 rbn E Belongs to the UPF0761 family
AKEMDJAB_00893 2.8e-85 ccl S cog cog4708
AKEMDJAB_00894 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AKEMDJAB_00895 2.6e-183 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
AKEMDJAB_00897 1.3e-171 yfjR K regulation of single-species biofilm formation
AKEMDJAB_00899 7.5e-72 S QueT transporter
AKEMDJAB_00900 4.1e-158 xth 3.1.11.2 L exodeoxyribonuclease III
AKEMDJAB_00902 4.6e-199 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AKEMDJAB_00903 2.9e-17 yjdB S Domain of unknown function (DUF4767)
AKEMDJAB_00904 1.1e-166 tehB 2.1.1.265 PQ tellurite resistance protein tehb
AKEMDJAB_00905 4.2e-157 O protein import
AKEMDJAB_00906 2.6e-124 agrA KT phosphorelay signal transduction system
AKEMDJAB_00907 6.9e-200 2.7.13.3 T protein histidine kinase activity
AKEMDJAB_00909 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
AKEMDJAB_00910 1.5e-36 ylqC L Belongs to the UPF0109 family
AKEMDJAB_00911 1.2e-233 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
AKEMDJAB_00912 0.0 ydaO E amino acid
AKEMDJAB_00913 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
AKEMDJAB_00914 5e-145 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AKEMDJAB_00915 3e-289 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
AKEMDJAB_00916 4.5e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AKEMDJAB_00917 1.4e-81 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AKEMDJAB_00918 1.4e-167 murB 1.3.1.98 M cell wall formation
AKEMDJAB_00919 5.2e-212 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
AKEMDJAB_00920 2e-138 potB P ABC-type spermidine putrescine transport system, permease component I
AKEMDJAB_00921 2.3e-131 potC P ABC-type spermidine putrescine transport system, permease component II
AKEMDJAB_00922 2.6e-205 potD P spermidine putrescine ABC transporter
AKEMDJAB_00923 1.9e-145 XK27_08050 O HflC and HflK could regulate a protease
AKEMDJAB_00924 1.8e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
AKEMDJAB_00925 5.2e-13 GK ROK family
AKEMDJAB_00926 1.7e-114 GK ROK family
AKEMDJAB_00927 1.1e-208 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AKEMDJAB_00928 3e-104 wecD M Acetyltransferase (GNAT) domain
AKEMDJAB_00929 7.7e-219 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AKEMDJAB_00930 8.3e-74 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
AKEMDJAB_00931 1.6e-58 arsC 1.20.4.1 P Belongs to the ArsC family
AKEMDJAB_00933 1e-55 lrgA S Effector of murein hydrolase LrgA
AKEMDJAB_00934 3.2e-116 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
AKEMDJAB_00935 2.3e-96 3.1.3.18 S IA, variant 1
AKEMDJAB_00936 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AKEMDJAB_00937 3.8e-299 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AKEMDJAB_00938 9.1e-113 serB 3.1.3.3 E phosphoserine phosphatase
AKEMDJAB_00940 4e-151 EG Permeases of the drug metabolite transporter (DMT) superfamily
AKEMDJAB_00942 1.7e-60 ycaO O OsmC-like protein
AKEMDJAB_00943 1.9e-62 paaI Q protein possibly involved in aromatic compounds catabolism
AKEMDJAB_00944 9.8e-10 O ADP-ribosylglycohydrolase
AKEMDJAB_00945 4.3e-127 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
AKEMDJAB_00947 8.8e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AKEMDJAB_00948 1.7e-17 XK27_00735
AKEMDJAB_00949 1.6e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
AKEMDJAB_00950 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
AKEMDJAB_00951 2e-161 S CAAX amino terminal protease family protein
AKEMDJAB_00953 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
AKEMDJAB_00954 9.2e-83 mutT 3.6.1.55 F Nudix family
AKEMDJAB_00955 1.9e-139 ET ABC transporter
AKEMDJAB_00956 5.9e-138 ET Belongs to the bacterial solute-binding protein 3 family
AKEMDJAB_00957 4.1e-198 arcT 2.6.1.1 E Aminotransferase
AKEMDJAB_00958 6.1e-135 gltS ET Belongs to the bacterial solute-binding protein 3 family
AKEMDJAB_00959 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
AKEMDJAB_00960 6.4e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
AKEMDJAB_00961 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
AKEMDJAB_00962 4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
AKEMDJAB_00963 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
AKEMDJAB_00964 3e-170 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
AKEMDJAB_00965 1.7e-159 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
AKEMDJAB_00966 1.6e-123 ycbB S Glycosyl transferase family 2
AKEMDJAB_00967 1.3e-46 XK27_09090 S Uncharacterized conserved protein (DUF2304)
AKEMDJAB_00968 2.3e-216 amrA S polysaccharide biosynthetic process
AKEMDJAB_00969 1.8e-128 2.7.8.12 M transferase activity, transferring glycosyl groups
AKEMDJAB_00970 1.3e-141 S Predicted membrane protein (DUF2142)
AKEMDJAB_00971 2.3e-215 rgpA GT4 M Domain of unknown function (DUF1972)
AKEMDJAB_00972 4.2e-175 rgpB GT2 M Glycosyltransferase, group 2 family protein
AKEMDJAB_00973 5.2e-142 rgpC GM Transport permease protein
AKEMDJAB_00974 4e-223 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
AKEMDJAB_00975 1.3e-182 rgpEc GT2 M Glycosyl transferase family 2
AKEMDJAB_00976 0.0 rgpF M Rhamnan synthesis protein F
AKEMDJAB_00977 1.5e-118 radC E Belongs to the UPF0758 family
AKEMDJAB_00978 4.4e-129 puuD T peptidase C26
AKEMDJAB_00979 5.6e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AKEMDJAB_00980 8.2e-60 XK27_04120 S Putative amino acid metabolism
AKEMDJAB_00981 3.3e-203 iscS 2.8.1.7 E Cysteine desulfurase
AKEMDJAB_00982 3.9e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AKEMDJAB_00983 6e-100 yjbK S Adenylate cyclase
AKEMDJAB_00984 2e-118 yjbM 2.7.6.5 S Gtp pyrophosphokinase
AKEMDJAB_00985 1.7e-151 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AKEMDJAB_00986 4.5e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
AKEMDJAB_00987 2.2e-174 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
AKEMDJAB_00988 0.0 amiA E ABC transporter, substrate-binding protein, family 5
AKEMDJAB_00989 5.5e-310 amiA E ABC transporter, substrate-binding protein, family 5
AKEMDJAB_00990 1.1e-273 amiC P ABC transporter (Permease
AKEMDJAB_00991 3.8e-165 amiD P ABC transporter (Permease
AKEMDJAB_00992 3e-201 oppD P Belongs to the ABC transporter superfamily
AKEMDJAB_00993 3.1e-170 oppF P Belongs to the ABC transporter superfamily
AKEMDJAB_00994 5.5e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AKEMDJAB_00995 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
AKEMDJAB_00996 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AKEMDJAB_00997 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AKEMDJAB_00998 1e-68 S cog cog4699
AKEMDJAB_01000 1.9e-86 sigH K DNA-templated transcription, initiation
AKEMDJAB_01001 5.8e-138 ykuT M mechanosensitive ion channel
AKEMDJAB_01002 5.2e-229 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
AKEMDJAB_01003 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
AKEMDJAB_01004 1.7e-309 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
AKEMDJAB_01005 1.4e-83 XK27_03960 S Protein of unknown function (DUF3013)
AKEMDJAB_01006 9.2e-77 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
AKEMDJAB_01007 1.8e-83 XK27_02675 K Acetyltransferase GNAT Family
AKEMDJAB_01008 2.6e-177 prmA J Ribosomal protein L11 methyltransferase
AKEMDJAB_01009 2.4e-133 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
AKEMDJAB_01010 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
AKEMDJAB_01011 7.1e-181 gap 1.2.1.12 C Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
AKEMDJAB_01012 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AKEMDJAB_01013 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
AKEMDJAB_01014 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AKEMDJAB_01015 4e-142 purR 2.4.2.7 F operon repressor
AKEMDJAB_01016 1.2e-177 cbf S 3'-5' exoribonuclease yhaM
AKEMDJAB_01017 3.3e-167 rmuC S RmuC domain protein
AKEMDJAB_01018 1.7e-111 thiN 2.7.6.2 H thiamine pyrophosphokinase
AKEMDJAB_01019 1e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
AKEMDJAB_01020 2.7e-160 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
AKEMDJAB_01022 2.5e-228 L Transposase
AKEMDJAB_01023 0.0 M domain protein
AKEMDJAB_01026 6.2e-233 mntH P H( )-stimulated, divalent metal cation uptake system
AKEMDJAB_01027 1.1e-33 XK27_12190 S protein conserved in bacteria
AKEMDJAB_01029 1.1e-87 bioY S biotin synthase
AKEMDJAB_01030 1.7e-251 yegQ O Peptidase U32
AKEMDJAB_01031 1.5e-177 yegQ O Peptidase U32
AKEMDJAB_01033 9.3e-69 ytxH S General stress protein
AKEMDJAB_01034 3.7e-08 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AKEMDJAB_01035 2.2e-145 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AKEMDJAB_01036 3.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AKEMDJAB_01037 2.2e-41 pspC KT PspC domain
AKEMDJAB_01038 0.0 GM domain, Protein
AKEMDJAB_01039 5.5e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
AKEMDJAB_01040 0.0 sbcC L ATPase involved in DNA repair
AKEMDJAB_01042 7.6e-163 metF 1.5.1.20 E reductase
AKEMDJAB_01043 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AKEMDJAB_01045 2.4e-311 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
AKEMDJAB_01046 0.0 3.6.3.8 P cation transport ATPase
AKEMDJAB_01047 1.8e-100 S CAAX amino terminal protease family protein
AKEMDJAB_01049 7.3e-110 V CAAX protease self-immunity
AKEMDJAB_01050 8.8e-27 lanR K sequence-specific DNA binding
AKEMDJAB_01051 4.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AKEMDJAB_01052 3.8e-176 ytxK 2.1.1.72 L DNA methylase
AKEMDJAB_01053 2e-12 comGF U Putative Competence protein ComGF
AKEMDJAB_01054 2e-71 comGF U Competence protein ComGF
AKEMDJAB_01055 3.1e-15 NU Type II secretory pathway pseudopilin
AKEMDJAB_01056 8.4e-70 cglD NU Competence protein
AKEMDJAB_01057 2.2e-43 comGC U Required for transformation and DNA binding
AKEMDJAB_01058 6.3e-143 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AKEMDJAB_01059 4.2e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AKEMDJAB_01060 5.4e-142 M domain, Protein
AKEMDJAB_01061 8.9e-114
AKEMDJAB_01062 9.9e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
AKEMDJAB_01063 1.6e-85 S Fusaric acid resistance protein-like
AKEMDJAB_01064 8.5e-63 glnR K Transcriptional regulator
AKEMDJAB_01065 2.6e-263 glnA 6.3.1.2 E glutamine synthetase
AKEMDJAB_01066 8e-114 pscB M CHAP domain protein
AKEMDJAB_01067 2.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AKEMDJAB_01068 4.4e-121 atpB C it plays a direct role in the translocation of protons across the membrane
AKEMDJAB_01069 1.6e-77 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AKEMDJAB_01070 8.7e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AKEMDJAB_01071 1e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AKEMDJAB_01072 4.8e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AKEMDJAB_01073 2.3e-262 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AKEMDJAB_01074 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
AKEMDJAB_01075 1.6e-217 ftsW D Belongs to the SEDS family
AKEMDJAB_01076 2.8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AKEMDJAB_01077 9.9e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
AKEMDJAB_01078 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AKEMDJAB_01080 1.3e-108 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AKEMDJAB_01081 1.1e-158 holB 2.7.7.7 L dna polymerase iii
AKEMDJAB_01082 5.8e-133 yaaT S stage 0 sporulation protein
AKEMDJAB_01083 1.2e-54 yabA L Involved in initiation control of chromosome replication
AKEMDJAB_01084 3.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AKEMDJAB_01085 1.3e-103 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
AKEMDJAB_01086 1.2e-141 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
AKEMDJAB_01087 5.4e-76 S Bacterial inner membrane protein
AKEMDJAB_01088 4.7e-114 3.4.17.14, 3.5.1.28 NU amidase activity
AKEMDJAB_01089 3.5e-294 nptA P COG1283 Na phosphate symporter
AKEMDJAB_01090 1.4e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
AKEMDJAB_01091 1.1e-207 S membrane
AKEMDJAB_01092 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
AKEMDJAB_01093 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
AKEMDJAB_01094 1.7e-38 ynzC S UPF0291 protein
AKEMDJAB_01095 6e-255 cycA E permease
AKEMDJAB_01096 3e-07 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AKEMDJAB_01097 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
AKEMDJAB_01098 3.9e-139 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AKEMDJAB_01100 2e-69 K Helix-turn-helix
AKEMDJAB_01101 2.3e-14
AKEMDJAB_01102 4.1e-17
AKEMDJAB_01104 4.7e-168 fhuR K transcriptional regulator (lysR family)
AKEMDJAB_01105 2.2e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AKEMDJAB_01106 4.2e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
AKEMDJAB_01107 4.8e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AKEMDJAB_01108 8.1e-222 pyrP F uracil Permease
AKEMDJAB_01109 2.5e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
AKEMDJAB_01110 9.3e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
AKEMDJAB_01111 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
AKEMDJAB_01112 5.8e-127 2.1.1.223 S Putative SAM-dependent methyltransferase
AKEMDJAB_01113 4.4e-180 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AKEMDJAB_01114 1.3e-120 macB V ABC transporter, ATP-binding protein
AKEMDJAB_01115 3.2e-212 V permease protein
AKEMDJAB_01116 1.9e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AKEMDJAB_01117 2.1e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
AKEMDJAB_01120 5.8e-103 XK27_00530 M CHAP domain protein
AKEMDJAB_01121 4.5e-103 abiGI K Transcriptional regulator, AbiEi antitoxin
AKEMDJAB_01122 7.1e-273 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
AKEMDJAB_01123 0.0 mdlB V abc transporter atp-binding protein
AKEMDJAB_01124 0.0 lmrA V abc transporter atp-binding protein
AKEMDJAB_01125 1.9e-197 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AKEMDJAB_01126 6.4e-123 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
AKEMDJAB_01127 4.5e-196 yceA S Belongs to the UPF0176 family
AKEMDJAB_01128 6.6e-114 S VIT family
AKEMDJAB_01129 1.5e-133 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
AKEMDJAB_01130 5e-215 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
AKEMDJAB_01131 3.9e-196 ald 1.4.1.1 C Belongs to the AlaDH PNT family
AKEMDJAB_01133 1.9e-128 E alpha/beta hydrolase fold
AKEMDJAB_01134 3.3e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AKEMDJAB_01135 5.1e-135 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
AKEMDJAB_01136 1e-168 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
AKEMDJAB_01137 4.9e-166 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
AKEMDJAB_01138 3.6e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
AKEMDJAB_01139 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
AKEMDJAB_01140 6e-247 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AKEMDJAB_01141 1.7e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
AKEMDJAB_01142 2.7e-23
AKEMDJAB_01143 7.7e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AKEMDJAB_01144 0.0 U protein secretion
AKEMDJAB_01145 5.2e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
AKEMDJAB_01146 1.7e-246 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
AKEMDJAB_01147 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AKEMDJAB_01148 1.4e-162 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
AKEMDJAB_01149 7.2e-200 S Protein of unknown function (DUF3114)
AKEMDJAB_01150 4.1e-29 pspC KT PspC domain protein
AKEMDJAB_01151 5.2e-119 yqfA K protein, Hemolysin III
AKEMDJAB_01152 3e-78 K hmm pf08876
AKEMDJAB_01153 4.7e-230 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
AKEMDJAB_01154 7.9e-216 mvaS 2.3.3.10 I synthase
AKEMDJAB_01155 1.7e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AKEMDJAB_01156 9.6e-94 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AKEMDJAB_01157 9.7e-22
AKEMDJAB_01158 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AKEMDJAB_01159 5.1e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
AKEMDJAB_01160 8.9e-251 mmuP E amino acid
AKEMDJAB_01161 4.1e-170 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
AKEMDJAB_01162 2.2e-30 S Domain of unknown function (DUF1912)
AKEMDJAB_01163 4.8e-13 L Helix-hairpin-helix DNA-binding motif class 1
AKEMDJAB_01164 8.7e-108 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
AKEMDJAB_01165 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
AKEMDJAB_01167 1.1e-10
AKEMDJAB_01168 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
AKEMDJAB_01169 1.7e-198 ilvE 2.6.1.42 E Aminotransferase
AKEMDJAB_01170 3.7e-16 S Protein of unknown function (DUF2969)
AKEMDJAB_01173 2.5e-204 rpsA 1.17.7.4 J ribosomal protein S1
AKEMDJAB_01176 4.6e-106 S Domain of Unknown Function with PDB structure (DUF3862)
AKEMDJAB_01177 6e-115 M Pfam SNARE associated Golgi protein
AKEMDJAB_01178 4.9e-171 S oxidoreductase
AKEMDJAB_01179 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
AKEMDJAB_01180 2.2e-84 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
AKEMDJAB_01181 0.0 clpE O Belongs to the ClpA ClpB family
AKEMDJAB_01182 9e-181 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AKEMDJAB_01183 1e-34 ykuJ S protein conserved in bacteria
AKEMDJAB_01184 1.7e-117 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
AKEMDJAB_01185 3.2e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
AKEMDJAB_01186 5.9e-77 feoA P FeoA domain protein
AKEMDJAB_01187 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
AKEMDJAB_01188 8.6e-08
AKEMDJAB_01189 4.4e-146 I Alpha/beta hydrolase family
AKEMDJAB_01190 1.1e-153 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AKEMDJAB_01191 3.1e-145 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AKEMDJAB_01192 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
AKEMDJAB_01193 2.2e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AKEMDJAB_01194 5.2e-145 licT K antiterminator
AKEMDJAB_01195 1.3e-87 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AKEMDJAB_01196 4.4e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
AKEMDJAB_01197 3.7e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AKEMDJAB_01198 1e-145 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
AKEMDJAB_01199 6.8e-99 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AKEMDJAB_01200 6.3e-188 mdtG EGP Major facilitator Superfamily
AKEMDJAB_01201 2e-33 secG U Preprotein translocase subunit SecG
AKEMDJAB_01202 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
AKEMDJAB_01203 3.6e-79 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
AKEMDJAB_01204 1.2e-274 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AKEMDJAB_01205 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
AKEMDJAB_01206 3.2e-195 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
AKEMDJAB_01207 4.1e-181 ccpA K Catabolite control protein A
AKEMDJAB_01208 1.6e-191 yyaQ S YjbR
AKEMDJAB_01209 1.3e-194 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
AKEMDJAB_01210 3.1e-75 yueI S Protein of unknown function (DUF1694)
AKEMDJAB_01211 6.5e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
AKEMDJAB_01212 4.6e-25 WQ51_00785
AKEMDJAB_01213 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
AKEMDJAB_01214 1.8e-215 ywbD 2.1.1.191 J Methyltransferase
AKEMDJAB_01215 2.4e-116 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
AKEMDJAB_01216 5.9e-160 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AKEMDJAB_01217 1.6e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AKEMDJAB_01218 6.4e-218 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AKEMDJAB_01219 2.4e-206 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
AKEMDJAB_01220 4.2e-53 yheA S Belongs to the UPF0342 family
AKEMDJAB_01221 3.2e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
AKEMDJAB_01222 3.7e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
AKEMDJAB_01223 2.5e-78 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AKEMDJAB_01224 2.5e-152 pheA 4.2.1.51 E Prephenate dehydratase
AKEMDJAB_01225 3.1e-246 msrR K Transcriptional regulator
AKEMDJAB_01226 2.6e-153 ydiA P C4-dicarboxylate transporter malic acid transport
AKEMDJAB_01227 2.9e-201 I acyl-CoA dehydrogenase
AKEMDJAB_01228 2.2e-96 mip S hydroperoxide reductase activity
AKEMDJAB_01229 1.6e-252 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AKEMDJAB_01230 1.9e-77 P Mediates zinc uptake. May also transport other divalent cations
AKEMDJAB_01231 2.4e-51 zupT P Mediates zinc uptake. May also transport other divalent cations
AKEMDJAB_01232 1.6e-61 smtB K Transcriptional regulator
AKEMDJAB_01233 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
AKEMDJAB_01235 5.6e-133 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
AKEMDJAB_01236 8.4e-131 S Domain of unknown function (DUF4336)
AKEMDJAB_01237 1.9e-201 yeaN P transporter
AKEMDJAB_01238 1.6e-149 yitS S EDD domain protein, DegV family
AKEMDJAB_01239 5.8e-95 XK27_08140 K Bacterial regulatory proteins, tetR family
AKEMDJAB_01240 7.1e-110 cutC P Participates in the control of copper homeostasis
AKEMDJAB_01242 4.1e-21 S Domain of unknown function (DUF4767)
AKEMDJAB_01243 4.7e-289 norB P Major facilitator superfamily
AKEMDJAB_01244 1.9e-95 tetR K transcriptional regulator
AKEMDJAB_01245 1.6e-157 S Domain of unknown function (DUF4300)
AKEMDJAB_01246 6.6e-131 V CAAX protease self-immunity
AKEMDJAB_01247 6.3e-156 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AKEMDJAB_01248 9.8e-135 fecE 3.6.3.34 HP ABC transporter
AKEMDJAB_01249 4.7e-172 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
AKEMDJAB_01250 2.1e-131 ybbA S Putative esterase
AKEMDJAB_01251 3.8e-81 Q Methyltransferase domain
AKEMDJAB_01252 8.8e-75 K TetR family transcriptional regulator
AKEMDJAB_01253 5.8e-49
AKEMDJAB_01254 1.9e-122 S CAAX protease self-immunity
AKEMDJAB_01255 4.5e-211 XK27_00195 K Mga helix-turn-helix domain
AKEMDJAB_01256 1.7e-28 glcT K transcriptional antiterminator
AKEMDJAB_01257 6.7e-292 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AKEMDJAB_01258 0.0 glpD 1.1.3.21, 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AKEMDJAB_01259 3.9e-125 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
AKEMDJAB_01261 3.7e-137 IQ Acetoin reductase
AKEMDJAB_01262 4.1e-21 S An automated process has identified a potential problem with this gene model
AKEMDJAB_01263 4.1e-60 S Protein of unknown function (DUF1722)
AKEMDJAB_01264 1.1e-62 yqeB S Pyrimidine dimer DNA glycosylase
AKEMDJAB_01266 6.5e-52
AKEMDJAB_01267 8.9e-94 S CAAX protease self-immunity
AKEMDJAB_01268 6e-117 estA E GDSL-like Lipase/Acylhydrolase
AKEMDJAB_01269 1.2e-101
AKEMDJAB_01270 2.1e-286 sulP P Sulfate permease and related transporters (MFS superfamily)
AKEMDJAB_01271 1.6e-146 ycgQ S TIGR03943 family
AKEMDJAB_01272 6e-155 XK27_03015 S permease
AKEMDJAB_01274 0.0 yhgF K Transcriptional accessory protein
AKEMDJAB_01275 1.3e-83 ydcK S Belongs to the SprT family
AKEMDJAB_01276 2.4e-153 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
AKEMDJAB_01277 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AKEMDJAB_01278 5.2e-142 tatD L Hydrolase, tatd
AKEMDJAB_01279 1.7e-70 yccU S CoA-binding protein
AKEMDJAB_01280 5.3e-50 trxA O Belongs to the thioredoxin family
AKEMDJAB_01281 5.6e-141 S Macro domain protein
AKEMDJAB_01282 6.3e-59 L thioesterase
AKEMDJAB_01283 6.3e-49 bta 1.8.1.8 CO cell redox homeostasis
AKEMDJAB_01286 1e-42 ydzE EG EamA-like transporter family
AKEMDJAB_01287 2.1e-103
AKEMDJAB_01288 8.3e-143 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
AKEMDJAB_01289 3e-139 glnQ 3.6.3.21 E abc transporter atp-binding protein
AKEMDJAB_01290 1.9e-147 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
AKEMDJAB_01291 1.9e-121 glnQ 3.6.3.21 E abc transporter atp-binding protein
AKEMDJAB_01292 2.6e-194 J Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs)
AKEMDJAB_01293 1.2e-103 S Domain of unknown function (DUF1803)
AKEMDJAB_01294 8.9e-162 ppaC 3.6.1.1 C inorganic pyrophosphatase
AKEMDJAB_01298 5.3e-11
AKEMDJAB_01300 2.6e-219 mutY L A G-specific adenine glycosylase
AKEMDJAB_01301 5e-43 XK27_05745
AKEMDJAB_01302 2.3e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
AKEMDJAB_01303 2.5e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
AKEMDJAB_01304 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AKEMDJAB_01306 2.9e-122 XK27_01040 S Protein of unknown function (DUF1129)
AKEMDJAB_01307 2.2e-168 corA P COG0598 Mg2 and Co2 transporters
AKEMDJAB_01308 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AKEMDJAB_01309 1.5e-191 V PFAM secretion protein HlyD family protein
AKEMDJAB_01316 3.5e-146 V 'abc transporter, ATP-binding protein
AKEMDJAB_01318 7e-187 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
AKEMDJAB_01319 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
AKEMDJAB_01320 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AKEMDJAB_01321 1.7e-61 yqhY S protein conserved in bacteria
AKEMDJAB_01322 8.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AKEMDJAB_01323 2e-180 scrR K Transcriptional regulator
AKEMDJAB_01324 3.1e-286 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
AKEMDJAB_01325 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
AKEMDJAB_01326 2e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
AKEMDJAB_01327 2.5e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
AKEMDJAB_01329 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
AKEMDJAB_01330 5.5e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AKEMDJAB_01331 1.2e-196 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AKEMDJAB_01332 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
AKEMDJAB_01333 7.8e-181 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AKEMDJAB_01334 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AKEMDJAB_01336 2.3e-159 V ABC transporter
AKEMDJAB_01337 6.6e-123
AKEMDJAB_01341 2.9e-31 yozG K Transcriptional regulator
AKEMDJAB_01343 8.8e-170 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
AKEMDJAB_01344 2.4e-259 XK27_03190 S hydrolases of the HAD superfamily
AKEMDJAB_01345 8.6e-117 yebC M Membrane
AKEMDJAB_01346 8.1e-310 KT response to antibiotic
AKEMDJAB_01347 1.3e-73 XK27_02470 K LytTr DNA-binding domain
AKEMDJAB_01348 5.3e-119 liaI S membrane
AKEMDJAB_01349 7.5e-194 mccF V LD-carboxypeptidase
AKEMDJAB_01350 1.7e-298 O MreB/Mbl protein
AKEMDJAB_01352 5.8e-146 V Psort location CytoplasmicMembrane, score
AKEMDJAB_01355 5.2e-14
AKEMDJAB_01356 1.1e-226 dcuS 2.7.13.3 T protein histidine kinase activity
AKEMDJAB_01357 6.2e-228 2.7.13.3 T protein histidine kinase activity
AKEMDJAB_01358 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AKEMDJAB_01359 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
AKEMDJAB_01360 1.8e-125 S Protein of unknown function (DUF554)
AKEMDJAB_01361 8.1e-134 ecsA_2 V abc transporter atp-binding protein
AKEMDJAB_01362 5.8e-286 XK27_00765
AKEMDJAB_01363 1.7e-140 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AKEMDJAB_01364 4.2e-223 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AKEMDJAB_01365 1e-58 yhaI J Membrane
AKEMDJAB_01366 5.4e-34 yhaI J Protein of unknown function (DUF805)
AKEMDJAB_01367 1.4e-60 yhaI J Protein of unknown function (DUF805)
AKEMDJAB_01368 4.5e-38 yhaI J Protein of unknown function (DUF805)
AKEMDJAB_01371 5.4e-99
AKEMDJAB_01372 9.7e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
AKEMDJAB_01373 2.4e-45 ftsL D cell division protein FtsL
AKEMDJAB_01374 0.0 ftsI 3.4.16.4 M penicillin-binding protein
AKEMDJAB_01375 1.1e-184 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AKEMDJAB_01376 8.3e-220 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
AKEMDJAB_01379 5.5e-256 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
AKEMDJAB_01380 1.8e-61 yutD J protein conserved in bacteria
AKEMDJAB_01381 1.8e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AKEMDJAB_01382 8e-91 XK27_09885 V Glycopeptide antibiotics resistance protein
AKEMDJAB_01385 0.0 mdlA V abc transporter atp-binding protein
AKEMDJAB_01386 0.0 mdlB V abc transporter atp-binding protein
AKEMDJAB_01392 1.8e-44 spiA K sequence-specific DNA binding
AKEMDJAB_01393 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
AKEMDJAB_01394 5.6e-150 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
AKEMDJAB_01395 2e-93 V CAAX protease self-immunity
AKEMDJAB_01396 4.7e-137 cppA E CppA N-terminal
AKEMDJAB_01397 3.7e-171 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
AKEMDJAB_01399 1.4e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AKEMDJAB_01400 6.6e-142 cah 4.2.1.1 P carbonic anhydrase
AKEMDJAB_01401 3.3e-37 L Transposase
AKEMDJAB_01402 6.7e-221 L Transposase
AKEMDJAB_01403 1.3e-193 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AKEMDJAB_01404 5e-76 ilvN 2.2.1.6 E Acetolactate synthase
AKEMDJAB_01405 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
AKEMDJAB_01406 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
AKEMDJAB_01407 4.2e-303 yloV S kinase related to dihydroxyacetone kinase
AKEMDJAB_01408 1.4e-57 asp S cog cog1302
AKEMDJAB_01409 6e-225 norN V Mate efflux family protein
AKEMDJAB_01410 5.6e-275 thrC 4.2.3.1 E Threonine synthase
AKEMDJAB_01413 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
AKEMDJAB_01414 0.0 pepO 3.4.24.71 O Peptidase family M13
AKEMDJAB_01415 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
AKEMDJAB_01416 0.0 treB 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
AKEMDJAB_01417 3.2e-26 treB 2.7.1.201 G pts system
AKEMDJAB_01418 6e-126 treR K trehalose operon
AKEMDJAB_01419 1.1e-95 ywlG S Belongs to the UPF0340 family
AKEMDJAB_01421 8.2e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
AKEMDJAB_01423 4.5e-244 6.3.2.2 H gamma-glutamylcysteine synthetase
AKEMDJAB_01424 4.4e-62 rplQ J ribosomal protein l17
AKEMDJAB_01425 3.6e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AKEMDJAB_01426 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AKEMDJAB_01427 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AKEMDJAB_01428 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
AKEMDJAB_01429 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AKEMDJAB_01430 2.1e-114 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
AKEMDJAB_01431 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
AKEMDJAB_01432 1.7e-57 rplO J binds to the 23S rRNA
AKEMDJAB_01433 1.9e-23 rpmD J ribosomal protein l30
AKEMDJAB_01434 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AKEMDJAB_01435 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AKEMDJAB_01436 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AKEMDJAB_01437 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AKEMDJAB_01438 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AKEMDJAB_01439 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AKEMDJAB_01440 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AKEMDJAB_01441 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AKEMDJAB_01442 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AKEMDJAB_01443 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
AKEMDJAB_01444 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AKEMDJAB_01445 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AKEMDJAB_01446 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AKEMDJAB_01447 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AKEMDJAB_01448 6.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AKEMDJAB_01449 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
AKEMDJAB_01450 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
AKEMDJAB_01451 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AKEMDJAB_01452 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
AKEMDJAB_01453 3.9e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
AKEMDJAB_01454 0.0 XK27_09800 I Acyltransferase
AKEMDJAB_01455 9.7e-36 XK27_09805 S MORN repeat protein
AKEMDJAB_01456 2.6e-79 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AKEMDJAB_01457 1e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AKEMDJAB_01458 5e-90 adk 2.7.4.3 F topology modulation protein
AKEMDJAB_01459 7.6e-50 yrvD S Lipopolysaccharide assembly protein A domain
AKEMDJAB_01460 1.5e-164 ltrA S Bacterial low temperature requirement A protein (LtrA)
AKEMDJAB_01461 4.9e-60 K sequence-specific DNA binding
AKEMDJAB_01462 4.3e-81 S Short repeat of unknown function (DUF308)
AKEMDJAB_01463 5e-90 K sequence-specific DNA binding
AKEMDJAB_01464 8.5e-155 L Replication initiation factor
AKEMDJAB_01465 1.9e-18 S Domain of unknown function (DUF3173)
AKEMDJAB_01466 5e-215 int L Belongs to the 'phage' integrase family
AKEMDJAB_01468 1.8e-234 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
AKEMDJAB_01469 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
AKEMDJAB_01470 6.3e-44 yrzL S Belongs to the UPF0297 family
AKEMDJAB_01471 1.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AKEMDJAB_01472 3.2e-44 yrzB S Belongs to the UPF0473 family
AKEMDJAB_01473 1.3e-288 ccs S the current gene model (or a revised gene model) may contain a frame shift
AKEMDJAB_01474 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
AKEMDJAB_01475 7.5e-14
AKEMDJAB_01476 2.4e-89 XK27_10930 K acetyltransferase
AKEMDJAB_01477 8.2e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AKEMDJAB_01478 4e-122 yaaA S Belongs to the UPF0246 family
AKEMDJAB_01479 9.3e-167 XK27_01785 S cog cog1284
AKEMDJAB_01480 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
AKEMDJAB_01482 2.5e-239 hisS 6.1.1.21 J histidyl-tRNA synthetase
AKEMDJAB_01483 3.2e-204 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
AKEMDJAB_01484 1.9e-219 metE 2.1.1.14 E Methionine synthase
AKEMDJAB_01485 1.5e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
AKEMDJAB_01486 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
AKEMDJAB_01489 1.4e-115 nudL L hydrolase
AKEMDJAB_01490 1.6e-52 K transcriptional regulator, PadR family
AKEMDJAB_01491 1e-70 XK27_06920 S Protein of unknown function (DUF1700)
AKEMDJAB_01492 1.1e-105 S Putative adhesin
AKEMDJAB_01493 6.8e-158 XK27_06930 V domain protein
AKEMDJAB_01494 2.2e-96 XK27_06935 K transcriptional regulator
AKEMDJAB_01495 4.1e-54 ypaA M Membrane
AKEMDJAB_01496 1.9e-10
AKEMDJAB_01497 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AKEMDJAB_01498 1.8e-47 veg S Biofilm formation stimulator VEG
AKEMDJAB_01499 1e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
AKEMDJAB_01500 2.2e-73 rplI J binds to the 23S rRNA
AKEMDJAB_01501 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
AKEMDJAB_01502 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
AKEMDJAB_01503 2.3e-97 yvbG U UPF0056 membrane protein
AKEMDJAB_01504 1.2e-218 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
AKEMDJAB_01505 1.5e-303 S Bacterial membrane protein, YfhO
AKEMDJAB_01506 1.8e-61 isaA GH23 M Immunodominant staphylococcal antigen A
AKEMDJAB_01507 2.7e-71 lytE M LysM domain protein
AKEMDJAB_01508 2.2e-132 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AKEMDJAB_01509 2.4e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AKEMDJAB_01510 2.7e-149 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AKEMDJAB_01511 5.9e-89 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AKEMDJAB_01512 2.4e-129 S sequence-specific DNA binding
AKEMDJAB_01513 5.9e-233 ymfH S Peptidase M16
AKEMDJAB_01514 4e-226 ymfF S Peptidase M16
AKEMDJAB_01515 6.4e-58 yaaA S S4 domain protein YaaA
AKEMDJAB_01516 6.3e-199 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AKEMDJAB_01517 1.1e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
AKEMDJAB_01518 7.2e-189 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
AKEMDJAB_01519 1.6e-152 yvjA S membrane
AKEMDJAB_01520 1.1e-305 ybiT S abc transporter atp-binding protein
AKEMDJAB_01521 0.0 XK27_10405 S Bacterial membrane protein YfhO
AKEMDJAB_01525 2.2e-117 yoaK S Protein of unknown function (DUF1275)
AKEMDJAB_01526 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AKEMDJAB_01527 1.5e-201 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
AKEMDJAB_01528 3.2e-133 parB K Belongs to the ParB family
AKEMDJAB_01529 2.2e-254 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AKEMDJAB_01530 5.5e-198 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
AKEMDJAB_01531 1.1e-29 yyzM S Protein conserved in bacteria
AKEMDJAB_01532 2.1e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
AKEMDJAB_01533 5.2e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
AKEMDJAB_01534 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AKEMDJAB_01535 2.2e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
AKEMDJAB_01536 8.7e-60 divIC D Septum formation initiator
AKEMDJAB_01538 8.4e-235 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
AKEMDJAB_01539 5.7e-228 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
AKEMDJAB_01540 7.6e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
AKEMDJAB_01541 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AKEMDJAB_01554 2.6e-10
AKEMDJAB_01560 4.9e-111 mreC M Involved in formation and maintenance of cell shape
AKEMDJAB_01561 1.1e-81 mreD M rod shape-determining protein MreD
AKEMDJAB_01562 7.9e-83 usp 3.5.1.28 CBM50 S CHAP domain
AKEMDJAB_01564 3.1e-25 K Transcriptional regulator
AKEMDJAB_01566 8e-80 L Transposase
AKEMDJAB_01567 3.9e-140 L overlaps another CDS with the same product name
AKEMDJAB_01569 2.7e-47
AKEMDJAB_01570 5.1e-40 S Entry exclusion protein 2
AKEMDJAB_01572 2.5e-138 tcyC2 3.6.3.21 E abc transporter atp-binding protein
AKEMDJAB_01573 1.9e-113 yxeN P ABC transporter, permease protein
AKEMDJAB_01574 1.5e-108 ytmL P ABC transporter (Permease
AKEMDJAB_01575 1.8e-164 ET ABC transporter substrate-binding protein
AKEMDJAB_01576 1.3e-174 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
AKEMDJAB_01577 2.1e-82 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
AKEMDJAB_01578 1.5e-42 S Sugar efflux transporter for intercellular exchange
AKEMDJAB_01579 8.3e-202 P FtsX-like permease family
AKEMDJAB_01580 1.1e-121 V abc transporter atp-binding protein
AKEMDJAB_01581 1.5e-98 K WHG domain
AKEMDJAB_01582 9.4e-172 ydhF S Aldo keto reductase
AKEMDJAB_01583 3.5e-206 natB CP ABC-type Na efflux pump, permease component
AKEMDJAB_01584 4.8e-165 natA S abc transporter atp-binding protein
AKEMDJAB_01585 1.2e-08 S Protein of unknown function (DUF3169)
AKEMDJAB_01586 2.5e-27 XK27_07105 K transcriptional
AKEMDJAB_01587 2.1e-38
AKEMDJAB_01588 5.1e-110 XK27_02070 S nitroreductase
AKEMDJAB_01589 1.3e-151 1.13.11.2 S glyoxalase
AKEMDJAB_01590 8.9e-75 ywnA K Transcriptional regulator
AKEMDJAB_01591 9.2e-153 E Alpha/beta hydrolase of unknown function (DUF915)
AKEMDJAB_01592 3.9e-224 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AKEMDJAB_01593 1.4e-167 bcrA V abc transporter atp-binding protein
AKEMDJAB_01594 2.1e-129 S ABC-2 family transporter protein
AKEMDJAB_01595 1e-130 T PhoQ Sensor
AKEMDJAB_01596 2.1e-123 T Xre family transcriptional regulator
AKEMDJAB_01597 3.9e-108 drgA C nitroreductase
AKEMDJAB_01598 1.1e-103 yoaK S Protein of unknown function (DUF1275)
AKEMDJAB_01599 9.9e-39 DJ nuclease activity
AKEMDJAB_01600 7.1e-30 XK27_10490
AKEMDJAB_01601 8.6e-156 yvgN C reductase
AKEMDJAB_01602 3.7e-190 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
AKEMDJAB_01603 6.4e-309 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
AKEMDJAB_01604 4.2e-226 vncS 2.7.13.3 T Histidine kinase
AKEMDJAB_01605 1.5e-115 K Response regulator receiver domain protein
AKEMDJAB_01606 2.6e-234 vex3 V Efflux ABC transporter, permease protein
AKEMDJAB_01607 1.7e-108 vex2 V abc transporter atp-binding protein
AKEMDJAB_01608 1.3e-179 vex1 V Efflux ABC transporter, permease protein
AKEMDJAB_01609 1.9e-283 XK27_07020 S Belongs to the UPF0371 family
AKEMDJAB_01611 1.1e-195 gldA 1.1.1.6 C glycerol dehydrogenase
AKEMDJAB_01612 3.2e-178 XK27_10475 S oxidoreductase
AKEMDJAB_01613 3.1e-57 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
AKEMDJAB_01614 1.2e-95 dhaL 2.7.1.121 S Dihydroxyacetone kinase
AKEMDJAB_01615 2.3e-176 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
AKEMDJAB_01616 2.2e-224 thrE K Psort location CytoplasmicMembrane, score
AKEMDJAB_01617 1e-132 T Ser Thr phosphatase family protein
AKEMDJAB_01618 7.2e-34 S Immunity protein 41
AKEMDJAB_01620 7.8e-191 mccF V LD-carboxypeptidase
AKEMDJAB_01621 1.6e-15 S integral membrane protein
AKEMDJAB_01622 4.2e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
AKEMDJAB_01623 9e-117 yhfC S Putative membrane peptidase family (DUF2324)
AKEMDJAB_01624 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
AKEMDJAB_01626 8e-253 S dextransucrase activity
AKEMDJAB_01627 9.9e-25
AKEMDJAB_01628 6.6e-23
AKEMDJAB_01629 2.7e-13
AKEMDJAB_01630 1.8e-14
AKEMDJAB_01631 4.1e-18
AKEMDJAB_01632 1.3e-36
AKEMDJAB_01633 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
AKEMDJAB_01634 1e-07 M Putative cell wall binding repeat
AKEMDJAB_01635 2.5e-100 M Putative cell wall binding repeat
AKEMDJAB_01636 5.5e-227 M Putative cell wall binding repeat
AKEMDJAB_01637 4.9e-90 S dextransucrase activity
AKEMDJAB_01638 0.0 S dextransucrase activity
AKEMDJAB_01639 4.7e-100 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AKEMDJAB_01640 1.8e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AKEMDJAB_01641 0.0 M Putative cell wall binding repeat
AKEMDJAB_01642 7.8e-178 M Putative cell wall binding repeat
AKEMDJAB_01643 0.0 M Putative cell wall binding repeat
AKEMDJAB_01644 1.2e-224 S dextransucrase activity
AKEMDJAB_01646 4.6e-99 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AKEMDJAB_01647 4.2e-159 mleP S Sodium Bile acid symporter family
AKEMDJAB_01648 0.0 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme, NAD binding domain
AKEMDJAB_01649 4.7e-47 K Helix-turn-helix
AKEMDJAB_01650 4.4e-118 mleR K malolactic fermentation system
AKEMDJAB_01651 1e-115 XK27_00785 S CAAX protease self-immunity
AKEMDJAB_01652 3.8e-233 EGP Major facilitator Superfamily
AKEMDJAB_01653 1.9e-63 rmaI K Transcriptional regulator, MarR family
AKEMDJAB_01654 1.9e-90 maa 2.3.1.79 GK Maltose O-acetyltransferase
AKEMDJAB_01655 3.8e-111 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
AKEMDJAB_01656 0.0 3.5.1.28 M domain protein
AKEMDJAB_01657 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
AKEMDJAB_01658 2.3e-22
AKEMDJAB_01661 2.6e-94 XK27_05505 S Psort location CytoplasmicMembrane, score
AKEMDJAB_01662 4.6e-143 P molecular chaperone
AKEMDJAB_01663 5.6e-98 S Carbohydrate-binding domain-containing protein Cthe_2159
AKEMDJAB_01664 2.3e-171 XK27_08075 M glycosyl transferase family 2
AKEMDJAB_01665 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
AKEMDJAB_01666 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
AKEMDJAB_01667 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
AKEMDJAB_01668 1.4e-227 rodA D Belongs to the SEDS family
AKEMDJAB_01669 3e-243 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AKEMDJAB_01670 1.5e-112 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
AKEMDJAB_01671 1.2e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
AKEMDJAB_01672 7.4e-138 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
AKEMDJAB_01673 1.1e-19 Q Methyltransferase domain
AKEMDJAB_01674 6.1e-67 GnaT 2.5.1.16 K acetyltransferase
AKEMDJAB_01675 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
AKEMDJAB_01676 4.9e-93 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AKEMDJAB_01677 3e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AKEMDJAB_01678 6.5e-125 dnaD
AKEMDJAB_01679 3.8e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AKEMDJAB_01681 2.8e-233 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AKEMDJAB_01682 4.6e-29 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AKEMDJAB_01683 1.8e-156 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
AKEMDJAB_01684 2.2e-148 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
AKEMDJAB_01685 6.3e-73 argR K Regulates arginine biosynthesis genes
AKEMDJAB_01686 3.9e-301 recN L May be involved in recombinational repair of damaged DNA
AKEMDJAB_01687 7.1e-142 DegV S DegV family
AKEMDJAB_01688 6.6e-159 ypmR E COG2755 Lysophospholipase L1 and related esterases
AKEMDJAB_01689 2e-95 ypmS S Protein conserved in bacteria
AKEMDJAB_01690 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
AKEMDJAB_01692 1.4e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
AKEMDJAB_01693 3.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AKEMDJAB_01694 5.4e-53 hxlR K HxlR-like helix-turn-helix
AKEMDJAB_01695 5.7e-70 S SnoaL-like polyketide cyclase
AKEMDJAB_01696 6.2e-54 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AKEMDJAB_01697 1.1e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AKEMDJAB_01698 3.3e-189 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
AKEMDJAB_01699 3.5e-37 ysdA L Membrane
AKEMDJAB_01700 1.4e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AKEMDJAB_01701 1.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AKEMDJAB_01702 0.0 dnaE 2.7.7.7 L DNA polymerase
AKEMDJAB_01703 2.6e-186 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
AKEMDJAB_01704 1e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
AKEMDJAB_01705 0.0 Q the current gene model (or a revised gene model) may contain a frame shift
AKEMDJAB_01706 1.7e-18 S Domain of unknown function (DUF4649)
AKEMDJAB_01707 6.2e-177 XK27_08835 S ABC transporter substrate binding protein
AKEMDJAB_01708 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
AKEMDJAB_01709 5.8e-135 XK27_08845 S abc transporter atp-binding protein
AKEMDJAB_01710 1.3e-309 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AKEMDJAB_01711 8.9e-147 estA CE1 S Esterase
AKEMDJAB_01712 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
AKEMDJAB_01713 2.2e-18 XK27_08880
AKEMDJAB_01714 1e-75 fld C Flavodoxin
AKEMDJAB_01715 6.8e-276 clcA P Chloride transporter, ClC family
AKEMDJAB_01716 2.8e-39 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
AKEMDJAB_01717 1.6e-211 XK27_05110 P Chloride transporter ClC family
AKEMDJAB_01718 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
AKEMDJAB_01721 3.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
AKEMDJAB_01722 1.6e-160 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AKEMDJAB_01723 1.8e-84 ytsP 1.8.4.14 T GAF domain-containing protein
AKEMDJAB_01724 1e-301 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AKEMDJAB_01725 1.6e-171 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
AKEMDJAB_01726 2.3e-210 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AKEMDJAB_01727 6.7e-275 5.1.3.2 GM Psort location CytoplasmicMembrane, score
AKEMDJAB_01728 1.3e-144
AKEMDJAB_01729 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
AKEMDJAB_01730 6.1e-271 pelF GT4 M Domain of unknown function (DUF3492)
AKEMDJAB_01731 4.9e-183 pelG M Putative exopolysaccharide Exporter (EPS-E)
AKEMDJAB_01732 1.7e-222 cotH M CotH kinase protein
AKEMDJAB_01733 3e-96 P VTC domain
AKEMDJAB_01734 9.2e-84 S membrane
AKEMDJAB_01735 1.7e-135 G Domain of unknown function (DUF4832)
AKEMDJAB_01736 7.4e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
AKEMDJAB_01738 5.5e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AKEMDJAB_01739 7.2e-26 epuA S DNA-directed RNA polymerase subunit beta
AKEMDJAB_01740 6.1e-152 endA F DNA RNA non-specific endonuclease
AKEMDJAB_01741 9.6e-76 L Transposase
AKEMDJAB_01742 9.9e-136 L Transposase and inactivated derivatives
AKEMDJAB_01743 2.2e-73 yhaI S Protein of unknown function (DUF805)
AKEMDJAB_01744 2.2e-148 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
AKEMDJAB_01745 3.3e-272 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AKEMDJAB_01746 2.3e-216 macB_2 V FtsX-like permease family
AKEMDJAB_01747 6.2e-120 yhcA V abc transporter atp-binding protein
AKEMDJAB_01748 1.2e-121 mta K Transcriptional
AKEMDJAB_01749 1.8e-32 S Protein of unknown function (DUF3021)
AKEMDJAB_01750 7.6e-74 K COG3279 Response regulator of the LytR AlgR family
AKEMDJAB_01751 1.9e-131 cylB V ABC-2 type transporter
AKEMDJAB_01752 1.1e-150 cylA V abc transporter atp-binding protein
AKEMDJAB_01753 4.1e-223 S COG1073 Hydrolases of the alpha beta superfamily
AKEMDJAB_01754 1.9e-72 K helix_turn_helix multiple antibiotic resistance protein
AKEMDJAB_01755 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
AKEMDJAB_01756 5e-134 glcR K transcriptional regulator (DeoR family)
AKEMDJAB_01757 8.1e-143 cof S Sucrose-6F-phosphate phosphohydrolase
AKEMDJAB_01758 2e-49 pgpB 3.6.1.27 I phosphatidate phosphatase activity
AKEMDJAB_01759 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
AKEMDJAB_01760 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
AKEMDJAB_01761 6.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
AKEMDJAB_01762 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
AKEMDJAB_01763 1.6e-160 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
AKEMDJAB_01764 5.2e-56 S TM2 domain
AKEMDJAB_01765 3.8e-45
AKEMDJAB_01767 3.4e-286 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
AKEMDJAB_01768 4.9e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AKEMDJAB_01769 1.4e-142 cmpC S abc transporter atp-binding protein
AKEMDJAB_01770 0.0 WQ51_06230 S ABC transporter
AKEMDJAB_01771 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
AKEMDJAB_01772 6.5e-232 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
AKEMDJAB_01773 9.3e-144 cdsA 2.7.7.41 S Belongs to the CDS family
AKEMDJAB_01774 1.2e-140 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AKEMDJAB_01775 2e-47 yajC U protein transport
AKEMDJAB_01776 6.1e-126 yeeN K transcriptional regulatory protein
AKEMDJAB_01777 3.3e-68 V ABC transporter
AKEMDJAB_01778 4.8e-21 tal 2.2.1.2 H Transaldolase
AKEMDJAB_01779 1.1e-33 srlB 2.7.1.198 G sorbitol-specific, IIA component
AKEMDJAB_01780 2.2e-158 srlE 2.7.1.198 G PTS sorbitol transporter subunit IIB
AKEMDJAB_01781 2.4e-82 srlA G PTS system glucitol sorbitol-specific
AKEMDJAB_01782 5.2e-57 gutM K Glucitol operon activator
AKEMDJAB_01783 1e-36 srlM 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
AKEMDJAB_01784 6e-106 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
AKEMDJAB_01785 7e-304 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
AKEMDJAB_01786 3.3e-234 pgi 5.3.1.9 G Belongs to the GPI family
AKEMDJAB_01787 1.4e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
AKEMDJAB_01788 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
AKEMDJAB_01789 8.1e-163 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
AKEMDJAB_01790 6.6e-129 adcB P ABC transporter (Permease
AKEMDJAB_01791 9.2e-135 adcC P ABC transporter, ATP-binding protein
AKEMDJAB_01792 5.9e-71 adcR K transcriptional
AKEMDJAB_01793 2.8e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AKEMDJAB_01794 5.6e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AKEMDJAB_01795 2.7e-26
AKEMDJAB_01796 2.9e-273 sufB O assembly protein SufB
AKEMDJAB_01797 9.4e-74 nifU C SUF system FeS assembly protein, NifU family
AKEMDJAB_01798 2.8e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AKEMDJAB_01799 1.2e-233 sufD O assembly protein SufD
AKEMDJAB_01800 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
AKEMDJAB_01801 3.9e-183 tagO 2.7.8.33, 2.7.8.35 M transferase
AKEMDJAB_01802 1.2e-124 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
AKEMDJAB_01803 4.8e-18 S Protein of unknown function (DUF3021)
AKEMDJAB_01804 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
AKEMDJAB_01805 1.2e-272 glnP P ABC transporter
AKEMDJAB_01806 2.2e-123 glnQ E abc transporter atp-binding protein
AKEMDJAB_01807 1.1e-182 D nuclear chromosome segregation
AKEMDJAB_01808 8.1e-84 V VanZ like family
AKEMDJAB_01809 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AKEMDJAB_01810 4e-191 yhjX P Major Facilitator
AKEMDJAB_01811 2.2e-111 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
AKEMDJAB_01812 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
AKEMDJAB_01813 1.3e-235 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AKEMDJAB_01814 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
AKEMDJAB_01815 2.6e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
AKEMDJAB_01816 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AKEMDJAB_01817 3.1e-83 nrdI F Belongs to the NrdI family
AKEMDJAB_01818 1.3e-254 pepC 3.4.22.40 E aminopeptidase
AKEMDJAB_01819 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
AKEMDJAB_01820 4.3e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
AKEMDJAB_01821 8.3e-93 ypsA S Belongs to the UPF0398 family
AKEMDJAB_01822 2.2e-38 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
AKEMDJAB_01823 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
AKEMDJAB_01824 8e-277 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
AKEMDJAB_01825 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
AKEMDJAB_01826 1.4e-21
AKEMDJAB_01827 5.7e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
AKEMDJAB_01828 2.2e-87 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
AKEMDJAB_01829 9.6e-299 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AKEMDJAB_01830 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
AKEMDJAB_01831 7.7e-166 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AKEMDJAB_01832 9.2e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
AKEMDJAB_01833 3.9e-128 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AKEMDJAB_01834 9.6e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
AKEMDJAB_01835 3.2e-100 ybhL S Belongs to the BI1 family
AKEMDJAB_01836 4.2e-12 ycdA S Domain of unknown function (DUF4352)
AKEMDJAB_01837 6.2e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
AKEMDJAB_01838 1.8e-90 K transcriptional regulator
AKEMDJAB_01839 1.6e-36 yneF S UPF0154 protein
AKEMDJAB_01840 4.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
AKEMDJAB_01841 1.9e-183 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AKEMDJAB_01842 5.1e-98 XK27_09740 S Phosphoesterase
AKEMDJAB_01843 1.2e-85 ykuL S CBS domain
AKEMDJAB_01844 4.4e-130 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
AKEMDJAB_01845 1.4e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AKEMDJAB_01846 1.3e-94 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AKEMDJAB_01847 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
AKEMDJAB_01848 1.4e-13 yidD M Could be involved in insertion of integral membrane proteins into the membrane
AKEMDJAB_01849 1.8e-257 trkH P Cation transport protein
AKEMDJAB_01850 3.2e-245 trkA P Potassium transporter peripheral membrane component
AKEMDJAB_01851 1.8e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
AKEMDJAB_01852 3.2e-82 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AKEMDJAB_01853 4.9e-90 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
AKEMDJAB_01854 7.1e-156 K sequence-specific DNA binding
AKEMDJAB_01855 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
AKEMDJAB_01856 3.2e-53 yhaI L Membrane
AKEMDJAB_01857 1.8e-105 S Domain of unknown function (DUF4173)
AKEMDJAB_01858 7.8e-112 S Domain of unknown function (DUF4173)
AKEMDJAB_01859 6.8e-95 ureI S AmiS/UreI family transporter
AKEMDJAB_01860 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
AKEMDJAB_01861 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
AKEMDJAB_01862 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
AKEMDJAB_01863 6.6e-78 ureE O enzyme active site formation
AKEMDJAB_01864 1.7e-128 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
AKEMDJAB_01865 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AKEMDJAB_01866 3.4e-160 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
AKEMDJAB_01867 1.3e-176 cbiM P biosynthesis protein CbiM
AKEMDJAB_01868 3.2e-136 P cobalt transport protein
AKEMDJAB_01869 1.8e-130 cbiO P ABC transporter
AKEMDJAB_01870 5.3e-137 ET ABC transporter substrate-binding protein
AKEMDJAB_01871 7.8e-163 metQ M Belongs to the NlpA lipoprotein family
AKEMDJAB_01872 9.5e-261 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
AKEMDJAB_01873 6.4e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AKEMDJAB_01874 1.2e-99 metI P ABC transporter (Permease
AKEMDJAB_01875 7.4e-209 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AKEMDJAB_01876 2.3e-145 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
AKEMDJAB_01877 3e-93 S UPF0397 protein
AKEMDJAB_01878 1.6e-310 ykoD P abc transporter atp-binding protein
AKEMDJAB_01879 4.5e-149 cbiQ P cobalt transport
AKEMDJAB_01880 8e-120 ktrA P COG0569 K transport systems, NAD-binding component
AKEMDJAB_01881 8e-236 P COG0168 Trk-type K transport systems, membrane components
AKEMDJAB_01882 2.6e-129 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
AKEMDJAB_01883 6.2e-91 yceD K metal-binding, possibly nucleic acid-binding protein
AKEMDJAB_01884 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AKEMDJAB_01885 4.6e-280 T PhoQ Sensor
AKEMDJAB_01886 3e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AKEMDJAB_01887 7.4e-214 dnaB L Replication initiation and membrane attachment
AKEMDJAB_01888 4.4e-166 dnaI L Primosomal protein DnaI
AKEMDJAB_01889 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
AKEMDJAB_01890 1.5e-112
AKEMDJAB_01891 5.7e-236 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AKEMDJAB_01892 5.5e-62 manO S protein conserved in bacteria
AKEMDJAB_01893 4.3e-169 manN G PTS system mannose fructose sorbose family IID component
AKEMDJAB_01894 1.5e-112 manM G pts system
AKEMDJAB_01895 4.9e-174 manL 2.7.1.191 G pts system
AKEMDJAB_01896 5.4e-210 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
AKEMDJAB_01897 5.9e-224 mutH L DNA mismatch repair enzyme MutH
AKEMDJAB_01898 8.4e-11
AKEMDJAB_01899 1.7e-66 L T/G mismatch-specific endonuclease activity
AKEMDJAB_01900 3e-26
AKEMDJAB_01901 1.5e-34
AKEMDJAB_01902 2.4e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
AKEMDJAB_01903 3.7e-137 M LysM domain
AKEMDJAB_01904 8.4e-23
AKEMDJAB_01905 5.2e-175 S hydrolase
AKEMDJAB_01907 7.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
AKEMDJAB_01908 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AKEMDJAB_01909 3.5e-139 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
AKEMDJAB_01910 1.3e-26 P Hemerythrin HHE cation binding domain protein
AKEMDJAB_01911 1.8e-153 5.2.1.8 G hydrolase
AKEMDJAB_01912 3e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AKEMDJAB_01913 5.5e-193 MA20_36090 S Protein of unknown function (DUF2974)
AKEMDJAB_01914 5.5e-133 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
AKEMDJAB_01915 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
AKEMDJAB_01916 2.1e-280 hsdM 2.1.1.72 V type I restriction-modification system
AKEMDJAB_01917 3.4e-137 3.1.21.3 V Type I restriction modification DNA specificity domain
AKEMDJAB_01918 1.7e-135
AKEMDJAB_01919 9.1e-58
AKEMDJAB_01920 1.7e-54
AKEMDJAB_01921 6.7e-193 higA K Pfam:DUF955
AKEMDJAB_01922 7.2e-135 S double-stranded DNA endodeoxyribonuclease activity
AKEMDJAB_01923 6.8e-11 S double-stranded DNA endodeoxyribonuclease activity
AKEMDJAB_01924 0.0 2.4.1.21 GT5 M Right handed beta helix region
AKEMDJAB_01925 1.1e-173 spd F DNA RNA non-specific endonuclease
AKEMDJAB_01926 7.7e-92 lemA S LemA family
AKEMDJAB_01927 4e-135 htpX O Belongs to the peptidase M48B family
AKEMDJAB_01928 9.4e-118 sirR K iron dependent repressor
AKEMDJAB_01929 8e-171 sitA P Belongs to the bacterial solute-binding protein 9 family
AKEMDJAB_01930 2.3e-132 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
AKEMDJAB_01931 5.6e-127 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
AKEMDJAB_01932 1.4e-73 S Psort location CytoplasmicMembrane, score
AKEMDJAB_01933 3.6e-64 S Domain of unknown function (DUF4430)
AKEMDJAB_01934 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AKEMDJAB_01935 2.1e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
AKEMDJAB_01936 1.6e-111 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
AKEMDJAB_01937 1.7e-161 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
AKEMDJAB_01938 2.4e-105 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
AKEMDJAB_01939 1.1e-89 dps P Belongs to the Dps family
AKEMDJAB_01940 3.4e-79 perR P Belongs to the Fur family
AKEMDJAB_01941 7.1e-27 yqgQ S protein conserved in bacteria
AKEMDJAB_01942 1e-176 glk 2.7.1.2 G Glucokinase
AKEMDJAB_01943 0.0 typA T GTP-binding protein TypA
AKEMDJAB_01945 5.1e-251 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AKEMDJAB_01946 2.1e-199 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AKEMDJAB_01947 2.2e-133 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
AKEMDJAB_01948 1e-222 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
AKEMDJAB_01949 6.2e-233 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AKEMDJAB_01950 8.1e-120 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AKEMDJAB_01951 2.2e-86 sepF D cell septum assembly
AKEMDJAB_01952 2.9e-30 yggT D integral membrane protein
AKEMDJAB_01953 5e-145 ylmH S conserved protein, contains S4-like domain
AKEMDJAB_01954 8.4e-138 divIVA D Cell division initiation protein
AKEMDJAB_01955 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)