ORF_ID e_value Gene_name EC_number CAZy COGs Description
LHPNHANK_00001 1.1e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LHPNHANK_00002 1.2e-197 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LHPNHANK_00003 1.1e-29 yyzM S Protein conserved in bacteria
LHPNHANK_00004 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LHPNHANK_00005 3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LHPNHANK_00006 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LHPNHANK_00007 2.2e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
LHPNHANK_00008 3e-60 divIC D Septum formation initiator
LHPNHANK_00010 1.3e-238 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
LHPNHANK_00011 1.1e-236 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LHPNHANK_00012 2e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
LHPNHANK_00013 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LHPNHANK_00026 2.6e-10
LHPNHANK_00032 1.2e-106 mreC M Involved in formation and maintenance of cell shape
LHPNHANK_00033 1.9e-84 mreD M rod shape-determining protein MreD
LHPNHANK_00034 7.2e-91 usp 3.5.1.28 CBM50 S CHAP domain
LHPNHANK_00035 9.5e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LHPNHANK_00036 1.1e-217 araT 2.6.1.1 E Aminotransferase
LHPNHANK_00037 1.4e-139 recO L Involved in DNA repair and RecF pathway recombination
LHPNHANK_00038 9.5e-181 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LHPNHANK_00039 8.1e-30 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
LHPNHANK_00040 8.9e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
LHPNHANK_00041 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LHPNHANK_00042 4.5e-175
LHPNHANK_00043 1.2e-277 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LHPNHANK_00044 3.2e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
LHPNHANK_00045 6.8e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LHPNHANK_00046 2.8e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
LHPNHANK_00047 6.1e-238 purD 6.3.4.13 F Belongs to the GARS family
LHPNHANK_00048 9e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LHPNHANK_00049 3.3e-200 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LHPNHANK_00050 7.9e-174 1.1.1.169 H Ketopantoate reductase
LHPNHANK_00051 3.2e-11
LHPNHANK_00052 2.9e-36
LHPNHANK_00054 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LHPNHANK_00055 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
LHPNHANK_00056 3.1e-69 argR K Regulates arginine biosynthesis genes
LHPNHANK_00057 1.9e-56 ymcA 3.6.3.21 S Belongs to the UPF0342 family
LHPNHANK_00058 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LHPNHANK_00059 1.9e-77 S Protein of unknown function (DUF3021)
LHPNHANK_00060 2.4e-69 K LytTr DNA-binding domain
LHPNHANK_00062 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LHPNHANK_00064 2e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LHPNHANK_00065 2.2e-107 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
LHPNHANK_00066 1.5e-228 cinA 3.5.1.42 S Belongs to the CinA family
LHPNHANK_00067 1e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LHPNHANK_00068 4.6e-193 L PFAM Integrase, catalytic core
LHPNHANK_00069 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
LHPNHANK_00075 2.6e-10
LHPNHANK_00078 1.9e-07
LHPNHANK_00083 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LHPNHANK_00084 1.1e-236 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
LHPNHANK_00085 1.2e-35 XK27_02060 S Transglycosylase associated protein
LHPNHANK_00086 1.1e-71 badR K Transcriptional regulator, marr family
LHPNHANK_00087 8e-94 S reductase
LHPNHANK_00089 3.5e-288 ahpF O alkyl hydroperoxide reductase
LHPNHANK_00090 1.1e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
LHPNHANK_00091 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
LHPNHANK_00092 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LHPNHANK_00093 1.2e-82 S Putative small multi-drug export protein
LHPNHANK_00094 4.8e-76 ctsR K Belongs to the CtsR family
LHPNHANK_00095 0.0 clpC O Belongs to the ClpA ClpB family
LHPNHANK_00096 2e-233 dacA 3.4.16.4 M Belongs to the peptidase S11 family
LHPNHANK_00097 1.1e-228 dacA 3.4.16.4 M Belongs to the peptidase S11 family
LHPNHANK_00098 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
LHPNHANK_00099 1e-139 S SseB protein N-terminal domain
LHPNHANK_00100 3.3e-112 cysE 2.3.1.30 E serine acetyltransferase
LHPNHANK_00102 8.1e-257 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
LHPNHANK_00103 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LHPNHANK_00105 9.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LHPNHANK_00106 2.7e-91 yacP S RNA-binding protein containing a PIN domain
LHPNHANK_00107 4.1e-153 degV S DegV family
LHPNHANK_00109 5.1e-22 K Transcriptional
LHPNHANK_00110 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LHPNHANK_00111 7.3e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
LHPNHANK_00112 1.7e-89 S Protein conserved in bacteria
LHPNHANK_00113 6.7e-89 H Methyltransferase
LHPNHANK_00115 3.4e-101 cadD P cadmium resistance
LHPNHANK_00116 4.5e-55 cadC K Bacterial regulatory protein, arsR family
LHPNHANK_00117 1.6e-16
LHPNHANK_00118 2.6e-18
LHPNHANK_00119 1.5e-29 K Helix-turn-helix domain
LHPNHANK_00120 6e-85
LHPNHANK_00121 8.5e-140 srtB 3.4.22.70 S sortase, SrtB family
LHPNHANK_00122 3.9e-234 capA M Bacterial capsule synthesis protein
LHPNHANK_00123 6.1e-39 gcvR T UPF0237 protein
LHPNHANK_00124 2.3e-243 XK27_08635 S UPF0210 protein
LHPNHANK_00125 5.6e-132 ais G Phosphoglycerate mutase
LHPNHANK_00126 2.3e-142 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
LHPNHANK_00127 3.2e-101 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
LHPNHANK_00128 1.1e-184 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LHPNHANK_00129 7e-63 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LHPNHANK_00130 6e-303 dnaK O Heat shock 70 kDa protein
LHPNHANK_00131 8e-189 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LHPNHANK_00132 1.7e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LHPNHANK_00133 7.3e-138 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
LHPNHANK_00134 1.5e-80 hmpT S cog cog4720
LHPNHANK_00147 5.2e-77 L COG1943 Transposase and inactivated derivatives
LHPNHANK_00148 3.7e-141 L Integrase core domain protein
LHPNHANK_00149 2.9e-122 L Helix-turn-helix domain
LHPNHANK_00150 5.9e-88 sigH K DNA-templated transcription, initiation
LHPNHANK_00151 2.8e-140 ykuT M mechanosensitive ion channel
LHPNHANK_00152 5.2e-229 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LHPNHANK_00153 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LHPNHANK_00154 2.7e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LHPNHANK_00155 7.1e-83 XK27_03960 S Protein of unknown function (DUF3013)
LHPNHANK_00156 2.4e-75 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
LHPNHANK_00157 7.7e-177 prmA J Ribosomal protein L11 methyltransferase
LHPNHANK_00158 3.1e-133 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LHPNHANK_00159 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
LHPNHANK_00160 1.2e-82 nrdI F Belongs to the NrdI family
LHPNHANK_00161 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LHPNHANK_00162 2.2e-73 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LHPNHANK_00163 2.9e-122 L Helix-turn-helix domain
LHPNHANK_00164 3.7e-141 L Integrase core domain protein
LHPNHANK_00165 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
LHPNHANK_00166 8.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LHPNHANK_00167 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LHPNHANK_00168 3.1e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
LHPNHANK_00169 9.6e-198 yhjX P Major Facilitator
LHPNHANK_00170 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LHPNHANK_00171 1.4e-72 V VanZ like family
LHPNHANK_00172 1.9e-177 D nuclear chromosome segregation
LHPNHANK_00173 2.2e-123 glnQ E abc transporter atp-binding protein
LHPNHANK_00174 1.6e-272 glnP P ABC transporter
LHPNHANK_00175 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
LHPNHANK_00176 3.1e-17 S Protein of unknown function (DUF3021)
LHPNHANK_00177 5.9e-124 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
LHPNHANK_00178 3.9e-183 tagO 2.7.8.33, 2.7.8.35 M transferase
LHPNHANK_00179 2.4e-136 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
LHPNHANK_00180 6.3e-235 sufD O assembly protein SufD
LHPNHANK_00181 3.8e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LHPNHANK_00182 2.3e-72 nifU C SUF system FeS assembly protein, NifU family
LHPNHANK_00183 1e-273 sufB O assembly protein SufB
LHPNHANK_00184 1.1e-310 oppA E ABC transporter substrate-binding protein
LHPNHANK_00185 9.7e-161 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
LHPNHANK_00186 1.9e-165 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
LHPNHANK_00187 6.6e-198 oppD P Belongs to the ABC transporter superfamily
LHPNHANK_00188 5.8e-169 oppF P Belongs to the ABC transporter superfamily
LHPNHANK_00189 8e-26
LHPNHANK_00190 1.2e-157 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LHPNHANK_00191 2.8e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LHPNHANK_00192 2.9e-70 adcR K transcriptional
LHPNHANK_00193 9.2e-135 adcC P ABC transporter, ATP-binding protein
LHPNHANK_00194 5.6e-128 adcB P ABC transporter (Permease
LHPNHANK_00195 4.5e-161 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
LHPNHANK_00196 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
LHPNHANK_00197 1.5e-157 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
LHPNHANK_00198 2.6e-255 pgi 5.3.1.9 G Belongs to the GPI family
LHPNHANK_00199 2.2e-154 Z012_04635 K sequence-specific DNA binding
LHPNHANK_00200 4.8e-285 V ABC transporter
LHPNHANK_00201 9.4e-127 yeeN K transcriptional regulatory protein
LHPNHANK_00202 3.1e-48 yajC U protein transport
LHPNHANK_00203 5.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LHPNHANK_00204 8.5e-145 cdsA 2.7.7.41 S Belongs to the CDS family
LHPNHANK_00205 4.7e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
LHPNHANK_00206 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LHPNHANK_00207 0.0 WQ51_06230 S ABC transporter
LHPNHANK_00208 4e-142 cmpC S abc transporter atp-binding protein
LHPNHANK_00209 4.1e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LHPNHANK_00210 2e-286 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LHPNHANK_00212 3.8e-48
LHPNHANK_00213 1.4e-53 S TM2 domain
LHPNHANK_00214 3.1e-164 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LHPNHANK_00215 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LHPNHANK_00216 6.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
LHPNHANK_00217 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
LHPNHANK_00218 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
LHPNHANK_00219 3e-67 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
LHPNHANK_00220 7.8e-146 cof S Sucrose-6F-phosphate phosphohydrolase
LHPNHANK_00221 1e-134 glcR K transcriptional regulator (DeoR family)
LHPNHANK_00222 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
LHPNHANK_00223 3.8e-73 K transcriptional
LHPNHANK_00224 4.1e-239 S COG1073 Hydrolases of the alpha beta superfamily
LHPNHANK_00225 1.2e-25 yjdF S Protein of unknown function (DUF2992)
LHPNHANK_00226 1.9e-158 cylA V abc transporter atp-binding protein
LHPNHANK_00227 2.8e-130 cylB V ABC-2 type transporter
LHPNHANK_00228 9e-75 K COG3279 Response regulator of the LytR AlgR family
LHPNHANK_00229 4.4e-31 S Protein of unknown function (DUF3021)
LHPNHANK_00230 4.6e-126 mta K Transcriptional
LHPNHANK_00231 3e-122 yhcA V abc transporter atp-binding protein
LHPNHANK_00232 5.3e-221 macB_2 V FtsX-like permease family
LHPNHANK_00233 1.9e-272 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LHPNHANK_00234 4.1e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LHPNHANK_00235 1.1e-77 yhaI S Protein of unknown function (DUF805)
LHPNHANK_00236 2.2e-254 pepC 3.4.22.40 E aminopeptidase
LHPNHANK_00237 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LHPNHANK_00238 9.6e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LHPNHANK_00239 4e-95 ypsA S Belongs to the UPF0398 family
LHPNHANK_00240 9.6e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LHPNHANK_00241 3.3e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
LHPNHANK_00242 1.4e-276 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
LHPNHANK_00243 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
LHPNHANK_00244 7.4e-23
LHPNHANK_00245 4.7e-257 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
LHPNHANK_00246 4.1e-89 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
LHPNHANK_00247 1.6e-298 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LHPNHANK_00248 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LHPNHANK_00249 2.7e-144 L Integrase core domain protein
LHPNHANK_00250 2.9e-122 L Helix-turn-helix domain
LHPNHANK_00251 7.7e-166 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LHPNHANK_00252 2e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
LHPNHANK_00253 4.6e-129 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LHPNHANK_00254 7.3e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
LHPNHANK_00255 2.2e-101 ybhL S Belongs to the BI1 family
LHPNHANK_00256 7.1e-12 ycdA S Domain of unknown function (DUF4352)
LHPNHANK_00257 2.1e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LHPNHANK_00258 1.8e-90 K transcriptional regulator
LHPNHANK_00259 1.6e-36 yneF S UPF0154 protein
LHPNHANK_00260 5.8e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
LHPNHANK_00261 1.3e-184 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LHPNHANK_00262 3.9e-98 XK27_09740 S Phosphoesterase
LHPNHANK_00263 1.1e-86 ykuL S CBS domain
LHPNHANK_00264 1.9e-133 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
LHPNHANK_00265 4.1e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LHPNHANK_00266 2.2e-94 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LHPNHANK_00267 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LHPNHANK_00268 5.1e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
LHPNHANK_00269 4.9e-260 trkH P Cation transport protein
LHPNHANK_00270 1.2e-247 trkA P Potassium transporter peripheral membrane component
LHPNHANK_00271 6.1e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LHPNHANK_00272 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LHPNHANK_00273 1.4e-105 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
LHPNHANK_00274 3e-154 K sequence-specific DNA binding
LHPNHANK_00275 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
LHPNHANK_00276 6.4e-54 yhaI L Membrane
LHPNHANK_00277 1.6e-38 S Domain of unknown function (DUF4173)
LHPNHANK_00278 6.8e-95 ureI S AmiS/UreI family transporter
LHPNHANK_00279 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
LHPNHANK_00280 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
LHPNHANK_00281 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
LHPNHANK_00282 6.6e-78 ureE O enzyme active site formation
LHPNHANK_00283 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
LHPNHANK_00284 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LHPNHANK_00285 5.2e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
LHPNHANK_00286 1.3e-176 cbiM P biosynthesis protein CbiM
LHPNHANK_00287 1.1e-136 P cobalt transport protein
LHPNHANK_00288 1.4e-130 cbiO P ABC transporter
LHPNHANK_00289 6.3e-138 ET ABC transporter substrate-binding protein
LHPNHANK_00290 3.2e-164 metQ M Belongs to the NlpA lipoprotein family
LHPNHANK_00291 9.1e-264 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
LHPNHANK_00292 6.4e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LHPNHANK_00293 1.2e-99 metI P ABC transporter (Permease
LHPNHANK_00294 4.6e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
LHPNHANK_00295 6.1e-120 ktrA P COG0569 K transport systems, NAD-binding component
LHPNHANK_00296 7.2e-237 P COG0168 Trk-type K transport systems, membrane components
LHPNHANK_00297 1.3e-128 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
LHPNHANK_00298 1.2e-89 yceD K metal-binding, possibly nucleic acid-binding protein
LHPNHANK_00299 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LHPNHANK_00300 9.8e-283 T PhoQ Sensor
LHPNHANK_00301 1.4e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LHPNHANK_00302 2.3e-215 dnaB L Replication initiation and membrane attachment
LHPNHANK_00303 1.5e-166 dnaI L Primosomal protein DnaI
LHPNHANK_00304 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
LHPNHANK_00305 1.1e-102
LHPNHANK_00306 2e-228 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LHPNHANK_00307 2.7e-61 manO S protein conserved in bacteria
LHPNHANK_00308 3.3e-169 manN G PTS system mannose fructose sorbose family IID component
LHPNHANK_00309 1.7e-116 manM G pts system
LHPNHANK_00310 4.9e-174 manL 2.7.1.191 G pts system
LHPNHANK_00311 2e-67 manO S Protein conserved in bacteria
LHPNHANK_00312 3e-162 manN G PTS system mannose fructose sorbose family IID component
LHPNHANK_00313 6.3e-132 manY G pts system
LHPNHANK_00314 6.2e-169 manL 2.7.1.191 G pts system
LHPNHANK_00315 1.4e-138 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
LHPNHANK_00316 3.5e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
LHPNHANK_00317 5.6e-248 pbuO S permease
LHPNHANK_00318 4.7e-76 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
LHPNHANK_00319 6e-91 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
LHPNHANK_00320 2.8e-211 brpA K Transcriptional
LHPNHANK_00321 2.3e-81 rimP S Required for maturation of 30S ribosomal subunits
LHPNHANK_00322 2.4e-196 nusA K Participates in both transcription termination and antitermination
LHPNHANK_00323 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
LHPNHANK_00324 8e-42 ylxQ J ribosomal protein
LHPNHANK_00325 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LHPNHANK_00326 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LHPNHANK_00327 1.3e-99 yvdD 3.2.2.10 S Belongs to the LOG family
LHPNHANK_00328 1e-273 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LHPNHANK_00329 4.3e-287 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
LHPNHANK_00330 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
LHPNHANK_00331 1.1e-200 metB 2.5.1.48, 4.4.1.8 E cystathionine
LHPNHANK_00332 2.3e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
LHPNHANK_00333 0.0 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
LHPNHANK_00334 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
LHPNHANK_00335 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LHPNHANK_00336 3.7e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LHPNHANK_00337 3e-72 ylbF S Belongs to the UPF0342 family
LHPNHANK_00338 1.9e-46 ylbG S UPF0298 protein
LHPNHANK_00339 2.8e-213 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
LHPNHANK_00340 4.2e-145 livH E Belongs to the binding-protein-dependent transport system permease family
LHPNHANK_00341 4.9e-139 livM E Belongs to the binding-protein-dependent transport system permease family
LHPNHANK_00342 3.1e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
LHPNHANK_00343 1.6e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
LHPNHANK_00344 5.1e-111 acuB S CBS domain
LHPNHANK_00345 8.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
LHPNHANK_00346 2e-109 yvyE 3.4.13.9 S YigZ family
LHPNHANK_00347 1e-243 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LHPNHANK_00348 3.8e-82 comFC K competence protein
LHPNHANK_00349 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LHPNHANK_00357 3.5e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
LHPNHANK_00358 1.4e-107 S Domain of unknown function (DUF1803)
LHPNHANK_00359 7.8e-102 ygaC J Belongs to the UPF0374 family
LHPNHANK_00360 7.5e-138 recX 2.4.1.337 GT4 S Regulatory protein RecX
LHPNHANK_00361 1.2e-247 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LHPNHANK_00362 4e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
LHPNHANK_00363 5.3e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
LHPNHANK_00364 1.3e-111 S HAD hydrolase, family IA, variant 3
LHPNHANK_00365 2.1e-140 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
LHPNHANK_00366 5.2e-72 marR K Transcriptional regulator, MarR family
LHPNHANK_00367 1.1e-170 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LHPNHANK_00368 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
LHPNHANK_00369 2e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
LHPNHANK_00370 4.8e-160 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
LHPNHANK_00371 1.8e-125 IQ reductase
LHPNHANK_00372 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LHPNHANK_00373 5.6e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LHPNHANK_00374 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LHPNHANK_00375 5.4e-256 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
LHPNHANK_00376 4.3e-158 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LHPNHANK_00377 5.7e-138 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
LHPNHANK_00378 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LHPNHANK_00379 2.4e-207 rny D Endoribonuclease that initiates mRNA decay
LHPNHANK_00380 2e-124 fruR K transcriptional
LHPNHANK_00381 7.6e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
LHPNHANK_00382 0.0 fruA 2.7.1.202 G phosphotransferase system
LHPNHANK_00383 4.6e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LHPNHANK_00384 1.7e-232 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
LHPNHANK_00386 8e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
LHPNHANK_00387 6.3e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LHPNHANK_00388 1.8e-292 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
LHPNHANK_00389 2.8e-254 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
LHPNHANK_00390 1.1e-68 2.3.1.128 K acetyltransferase
LHPNHANK_00391 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
LHPNHANK_00392 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
LHPNHANK_00393 2.9e-133 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LHPNHANK_00394 5e-63 WQ51_03320 S cog cog4835
LHPNHANK_00395 2.9e-151 XK27_08360 S EDD domain protein, DegV family
LHPNHANK_00396 1.3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LHPNHANK_00397 2e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LHPNHANK_00398 0.0 yfmR S abc transporter atp-binding protein
LHPNHANK_00399 5e-26 U response to pH
LHPNHANK_00400 1.5e-130 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
LHPNHANK_00401 6.1e-210 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
LHPNHANK_00402 1.4e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
LHPNHANK_00403 7.8e-286 S Psort location CytoplasmicMembrane, score
LHPNHANK_00404 4.6e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
LHPNHANK_00405 3.3e-74 K DNA-binding transcription factor activity
LHPNHANK_00406 0.0 lmrA1 V abc transporter atp-binding protein
LHPNHANK_00407 0.0 lmrA2 V abc transporter atp-binding protein
LHPNHANK_00408 3.3e-112 K Acetyltransferase (GNAT) family
LHPNHANK_00409 3.7e-111 2.7.6.5 S Region found in RelA / SpoT proteins
LHPNHANK_00410 1.7e-117 T response regulator
LHPNHANK_00411 8.5e-213 sptS 2.7.13.3 T Histidine kinase
LHPNHANK_00412 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
LHPNHANK_00413 1.7e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LHPNHANK_00414 4.5e-160 cvfB S Protein conserved in bacteria
LHPNHANK_00415 3.7e-34 yozE S Belongs to the UPF0346 family
LHPNHANK_00416 6e-137 sip M LysM domain protein
LHPNHANK_00417 6.1e-191 phoH T phosphate starvation-inducible protein PhoH
LHPNHANK_00418 1.5e-236 L Transposase
LHPNHANK_00423 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LHPNHANK_00424 2.2e-159 S reductase
LHPNHANK_00425 6.1e-168 K transcriptional regulator (lysR family)
LHPNHANK_00426 6.2e-102 S CAAX amino terminal protease family protein
LHPNHANK_00427 4.6e-193 L PFAM Integrase, catalytic core
LHPNHANK_00428 1.7e-308 S Glucan-binding protein C
LHPNHANK_00429 7.3e-163 S CHAP domain
LHPNHANK_00430 1.3e-55 insK L Integrase core domain protein
LHPNHANK_00431 2e-49 L transposition
LHPNHANK_00432 3.8e-182 L the current gene model (or a revised gene model) may contain a
LHPNHANK_00433 3.5e-185 coiA 3.6.4.12 S Competence protein
LHPNHANK_00434 0.0 pepF E oligoendopeptidase F
LHPNHANK_00435 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
LHPNHANK_00436 1.9e-127 yrrM 2.1.1.104 S O-Methyltransferase
LHPNHANK_00437 3e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
LHPNHANK_00438 3.3e-83 yxjI S LURP-one-related
LHPNHANK_00439 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LHPNHANK_00440 5.2e-77 L COG1943 Transposase and inactivated derivatives
LHPNHANK_00441 9.1e-60 K sequence-specific DNA binding
LHPNHANK_00442 7.7e-09
LHPNHANK_00444 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
LHPNHANK_00445 4.3e-138 agrA KT response regulator
LHPNHANK_00446 3.1e-07
LHPNHANK_00447 5.6e-135 agrA KT response regulator
LHPNHANK_00448 2e-231 2.7.13.3 T GHKL domain
LHPNHANK_00450 0.0 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
LHPNHANK_00451 1.3e-142 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LHPNHANK_00452 2.9e-226 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
LHPNHANK_00453 5.9e-191 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LHPNHANK_00454 1.3e-218 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LHPNHANK_00455 5.6e-127 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
LHPNHANK_00456 1.2e-205 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
LHPNHANK_00457 1.6e-128 yxkH G deacetylase
LHPNHANK_00458 6.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
LHPNHANK_00459 3.1e-153 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LHPNHANK_00460 7e-148 rarD S Transporter
LHPNHANK_00461 7.5e-16 T peptidase
LHPNHANK_00462 3e-14 coiA 3.6.4.12 S Competence protein
LHPNHANK_00463 1.3e-107 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LHPNHANK_00464 5e-107 rimL 2.3.1.128, 5.2.1.8 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LHPNHANK_00465 5.7e-172 S Helix-hairpin-helix DNA-binding motif class 1
LHPNHANK_00466 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LHPNHANK_00467 0.0 T Nacht domain
LHPNHANK_00468 3.5e-214 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
LHPNHANK_00469 6.3e-293
LHPNHANK_00470 3.5e-56 lrgA S Effector of murein hydrolase LrgA
LHPNHANK_00471 3.2e-116 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
LHPNHANK_00472 7.9e-97 3.1.3.18 S IA, variant 1
LHPNHANK_00473 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LHPNHANK_00474 6e-305 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LHPNHANK_00475 2.2e-114 serB 3.1.3.3 E phosphoserine phosphatase
LHPNHANK_00476 2.3e-139 L PFAM transposase IS116 IS110 IS902 family
LHPNHANK_00477 4.7e-64 L Transposase (IS116 IS110 IS902 family)
LHPNHANK_00478 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
LHPNHANK_00479 3.9e-159 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LHPNHANK_00480 2e-52 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LHPNHANK_00481 3.8e-106 csn2 S CRISPR-associated protein (Cas_Csn2)
LHPNHANK_00482 2.5e-07 N PFAM Uncharacterised protein family UPF0150
LHPNHANK_00483 1.8e-151 EG Permeases of the drug metabolite transporter (DMT) superfamily
LHPNHANK_00485 4.1e-62 ycaO O OsmC-like protein
LHPNHANK_00486 3e-63 paaI Q protein possibly involved in aromatic compounds catabolism
LHPNHANK_00487 9.8e-10 O ADP-ribosylglycohydrolase
LHPNHANK_00488 4.4e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LHPNHANK_00490 6.7e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LHPNHANK_00491 1.7e-17 XK27_00735
LHPNHANK_00492 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
LHPNHANK_00493 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
LHPNHANK_00494 3.4e-169 S CAAX amino terminal protease family protein
LHPNHANK_00496 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LHPNHANK_00497 2e-88 MA20_25245 K Gnat family
LHPNHANK_00498 1.8e-113 ycaK 1.6.5.2 S NADPH-dependent FMN reductase
LHPNHANK_00499 7.6e-21 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LHPNHANK_00500 3.7e-84 mutT 3.6.1.55 F Nudix family
LHPNHANK_00501 9.3e-139 ET ABC transporter
LHPNHANK_00502 5.9e-138 ET Belongs to the bacterial solute-binding protein 3 family
LHPNHANK_00503 2.3e-209 arcT 2.6.1.1 E Aminotransferase
LHPNHANK_00504 7.2e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
LHPNHANK_00505 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
LHPNHANK_00506 9.8e-51 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LHPNHANK_00507 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LHPNHANK_00508 2.3e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LHPNHANK_00509 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
LHPNHANK_00510 2.5e-172 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
LHPNHANK_00511 1.9e-158 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LHPNHANK_00512 6.1e-213 rgpA GT4 M Domain of unknown function (DUF1972)
LHPNHANK_00513 1e-173 rgpB GT2 M Glycosyltransferase, group 2 family protein
LHPNHANK_00514 5.2e-142 rgpC GM Transport permease protein
LHPNHANK_00515 5.3e-223 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
LHPNHANK_00516 9.2e-184 rgpEc GT2 M Glycosyl transferase family 2
LHPNHANK_00517 0.0 rgpF M Rhamnan synthesis protein F
LHPNHANK_00518 4.3e-156 rfbJ M Glycosyl transferase family 2
LHPNHANK_00519 4.3e-46 M Psort location CytoplasmicMembrane, score
LHPNHANK_00520 7.5e-166
LHPNHANK_00521 1.8e-114 radC E Belongs to the UPF0758 family
LHPNHANK_00522 1.8e-127 puuD T peptidase C26
LHPNHANK_00523 2.1e-117 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LHPNHANK_00524 8.2e-60 XK27_04120 S Putative amino acid metabolism
LHPNHANK_00525 3.4e-200 iscS 2.8.1.7 E Cysteine desulfurase
LHPNHANK_00526 6.6e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LHPNHANK_00527 2.1e-100 yjbK S Adenylate cyclase
LHPNHANK_00528 2e-118 yjbM 2.7.6.5 S Gtp pyrophosphokinase
LHPNHANK_00529 7.5e-152 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LHPNHANK_00530 1.2e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
LHPNHANK_00531 1.1e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
LHPNHANK_00532 0.0 amiA E ABC transporter, substrate-binding protein, family 5
LHPNHANK_00533 1.1e-278 amiC P ABC transporter (Permease
LHPNHANK_00534 1.4e-167 amiD P ABC transporter (Permease
LHPNHANK_00535 6e-202 oppD P Belongs to the ABC transporter superfamily
LHPNHANK_00536 9.5e-172 oppF P Belongs to the ABC transporter superfamily
LHPNHANK_00537 5.3e-131 V Psort location CytoplasmicMembrane, score
LHPNHANK_00538 1.8e-119 skfE V abc transporter atp-binding protein
LHPNHANK_00539 5.6e-62 yvoA_1 K Transcriptional
LHPNHANK_00540 1.4e-147 supH S overlaps another CDS with the same product name
LHPNHANK_00541 3.5e-146 XK27_02985 S overlaps another CDS with the same product name
LHPNHANK_00542 1e-193 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LHPNHANK_00543 8.8e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
LHPNHANK_00544 7.9e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
LHPNHANK_00545 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LHPNHANK_00546 3.6e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LHPNHANK_00547 8e-249 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LHPNHANK_00548 4.8e-137 stp 3.1.3.16 T phosphatase
LHPNHANK_00549 8.9e-302 prkC 2.7.11.1 KLT serine threonine protein kinase
LHPNHANK_00550 4.1e-104 kcsA P Ion transport protein
LHPNHANK_00551 8.6e-117 yvqF S Membrane
LHPNHANK_00552 3.9e-171 vraS 2.7.13.3 T Histidine kinase
LHPNHANK_00553 1.4e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LHPNHANK_00556 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LHPNHANK_00557 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
LHPNHANK_00558 4.6e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
LHPNHANK_00559 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
LHPNHANK_00560 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
LHPNHANK_00561 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LHPNHANK_00562 1e-188 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LHPNHANK_00563 2.8e-181 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
LHPNHANK_00564 2.8e-284 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
LHPNHANK_00565 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
LHPNHANK_00566 5.5e-98 2.3.1.128 K Acetyltransferase GNAT Family
LHPNHANK_00567 3.6e-285 S Protein of unknown function (DUF3114)
LHPNHANK_00569 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
LHPNHANK_00570 3.6e-297 V abc transporter atp-binding protein
LHPNHANK_00571 0.0 V abc transporter atp-binding protein
LHPNHANK_00572 3.7e-189 XK27_10075 S abc transporter atp-binding protein
LHPNHANK_00573 0.0 glgE 2.3.1.12, 2.4.99.16, 3.2.1.1, 3.2.1.14 GH13,GH18 M Pilin isopeptide linkage domain protein
LHPNHANK_00574 0.0 M Pilin isopeptide linkage domain protein
LHPNHANK_00575 0.0 zmpB M signal peptide protein, YSIRK family
LHPNHANK_00576 0.0 GM domain, Protein
LHPNHANK_00577 7.9e-219 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
LHPNHANK_00578 0.0 sbcC L ATPase involved in DNA repair
LHPNHANK_00579 3.5e-30 1.3.5.4 C reductase
LHPNHANK_00580 3.8e-182 L the current gene model (or a revised gene model) may contain a
LHPNHANK_00581 3.4e-155 cat 2.3.1.28 S acetyltransferase'
LHPNHANK_00582 0.0 M family 8
LHPNHANK_00583 1e-146 epsH S acetyltransferase'
LHPNHANK_00584 6.2e-240 M Glycosyltransferase, family 8
LHPNHANK_00585 7.6e-288 tagE 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
LHPNHANK_00586 4e-194 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
LHPNHANK_00587 1.3e-185 nss M transferase activity, transferring glycosyl groups
LHPNHANK_00588 1.2e-235 M Glycosyltransferase, family 8
LHPNHANK_00589 1.5e-166 cpsJ M Glycosyltransferase group 2 family protein
LHPNHANK_00590 0.0 M cog cog1442
LHPNHANK_00591 6.4e-240 M family 8
LHPNHANK_00592 2.3e-165 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
LHPNHANK_00593 2.8e-309 asp1 S Accessory Sec system protein Asp1
LHPNHANK_00594 9.4e-302 asp2 3.4.11.5 S Accessory Sec system protein Asp2
LHPNHANK_00595 1.6e-68 asp3 S Accessory Sec system protein Asp3
LHPNHANK_00596 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LHPNHANK_00597 7e-12 S Accessory secretory protein Sec, Asp5
LHPNHANK_00602 6.8e-18 3.2.1.51 GH95 U LPXTG cell wall anchor motif
LHPNHANK_00603 1.5e-109 K Helix-turn-helix domain, rpiR family
LHPNHANK_00604 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
LHPNHANK_00605 0.0 3.5.1.28 M domain protein
LHPNHANK_00606 4.3e-87 V abc transporter atp-binding protein
LHPNHANK_00607 1.4e-14
LHPNHANK_00609 1.1e-73 K Transcriptional regulatory protein, C terminal
LHPNHANK_00610 4.4e-64 2.7.13.3 T Histidine kinase
LHPNHANK_00611 8e-89 maa 2.3.1.79 GK Maltose O-acetyltransferase
LHPNHANK_00612 4.5e-65 rmaI K Transcriptional regulator, MarR family
LHPNHANK_00613 4.2e-240 EGP Major facilitator Superfamily
LHPNHANK_00614 1.9e-108 XK27_00785 S CAAX protease self-immunity
LHPNHANK_00616 0.0 S dextransucrase activity
LHPNHANK_00617 0.0 S dextransucrase activity
LHPNHANK_00618 1.1e-302 S dextransucrase activity
LHPNHANK_00619 0.0 M Putative cell wall binding repeat
LHPNHANK_00620 2.4e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LHPNHANK_00621 6.4e-105 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LHPNHANK_00622 0.0 S dextransucrase activity
LHPNHANK_00623 7.3e-238 tcdB S dextransucrase activity
LHPNHANK_00624 2.5e-89 S dextransucrase activity
LHPNHANK_00625 0.0 S dextransucrase activity
LHPNHANK_00626 0.0 S dextransucrase activity
LHPNHANK_00627 0.0 S dextransucrase activity
LHPNHANK_00628 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
LHPNHANK_00629 2e-227 S dextransucrase activity
LHPNHANK_00631 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
LHPNHANK_00632 4.6e-121 yhfC S Putative membrane peptidase family (DUF2324)
LHPNHANK_00633 1.1e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
LHPNHANK_00634 2.1e-15 S integral membrane protein
LHPNHANK_00635 1.8e-195 mccF V LD-carboxypeptidase
LHPNHANK_00636 3.1e-08 S Enterocin A Immunity
LHPNHANK_00637 4.6e-33 S Immunity protein 41
LHPNHANK_00638 0.0 M Putative cell wall binding repeat
LHPNHANK_00639 2.8e-227 thrE K Psort location CytoplasmicMembrane, score
LHPNHANK_00640 7.2e-178 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
LHPNHANK_00641 1.7e-94 dhaL 2.7.1.121 S Dihydroxyacetone kinase
LHPNHANK_00642 1.4e-57 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
LHPNHANK_00643 1.6e-177 XK27_10475 S oxidoreductase
LHPNHANK_00644 1.4e-195 gldA 1.1.1.6 C glycerol dehydrogenase
LHPNHANK_00646 1.6e-282 XK27_07020 S Belongs to the UPF0371 family
LHPNHANK_00647 3.2e-147 msmR K AraC family transcriptional regulator
LHPNHANK_00648 0.0 rafA 3.2.1.22 G alpha-galactosidase
LHPNHANK_00649 4.8e-195 msmE G Bacterial extracellular solute-binding protein
LHPNHANK_00650 2.7e-144 msmF P Binding-protein-dependent transport system inner membrane component
LHPNHANK_00651 2.2e-143 msmG P ABC-type sugar transport system, permease component
LHPNHANK_00652 3e-188 msmX P Belongs to the ABC transporter superfamily
LHPNHANK_00653 3.5e-97 iolC 2.7.1.4 G pfkB family carbohydrate kinase
LHPNHANK_00654 2.5e-195 gtfA 2.4.1.329, 2.4.1.7 GH13 G Alpha amylase, catalytic domain
LHPNHANK_00655 5.4e-308 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
LHPNHANK_00656 3.4e-151 galR K Transcriptional regulator
LHPNHANK_00657 4.8e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LHPNHANK_00658 6.3e-287 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
LHPNHANK_00659 5.6e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LHPNHANK_00660 8.4e-201 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
LHPNHANK_00661 0.0 lacS G transporter
LHPNHANK_00662 0.0 lacL 3.2.1.23 G -beta-galactosidase
LHPNHANK_00663 3e-207 S Tetratricopeptide repeat
LHPNHANK_00664 1.5e-155 yvgN C reductase
LHPNHANK_00665 1.5e-102 yoaK S Protein of unknown function (DUF1275)
LHPNHANK_00666 9.5e-107 drgA C Nitroreductase
LHPNHANK_00667 9e-229 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LHPNHANK_00668 7.5e-155 E Alpha/beta hydrolase of unknown function (DUF915)
LHPNHANK_00669 3.6e-76 ywnA K Transcriptional regulator
LHPNHANK_00670 1.3e-146 1.13.11.2 S glyoxalase
LHPNHANK_00671 1.6e-108 XK27_02070 S nitroreductase
LHPNHANK_00672 1e-37
LHPNHANK_00673 5.5e-27 XK27_07105 K transcriptional
LHPNHANK_00674 1.1e-06 S Protein of unknown function (DUF3169)
LHPNHANK_00675 4.4e-169 ydhF S Aldo keto reductase
LHPNHANK_00676 8.1e-97 K WHG domain
LHPNHANK_00677 6e-123 V abc transporter atp-binding protein
LHPNHANK_00678 2.4e-201 P FtsX-like permease family
LHPNHANK_00679 1.5e-42 S Sugar efflux transporter for intercellular exchange
LHPNHANK_00680 3.3e-83 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
LHPNHANK_00681 0.0 S dextransucrase activity
LHPNHANK_00682 4.6e-215 yfnA E amino acid
LHPNHANK_00683 2.6e-50 XK27_01300 P Protein conserved in bacteria
LHPNHANK_00684 7.5e-121 S Carbohydrate-binding domain-containing protein Cthe_2159
LHPNHANK_00685 1.9e-18 csbD K CsbD-like
LHPNHANK_00686 7.3e-107 S Protein of unknown function (DUF421)
LHPNHANK_00687 1.8e-59 S Protein of unknown function (DUF3290)
LHPNHANK_00688 3.9e-181 manA 5.3.1.8 G mannose-6-phosphate isomerase
LHPNHANK_00689 2.3e-232 brnQ E Component of the transport system for branched-chain amino acids
LHPNHANK_00690 2e-180 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LHPNHANK_00692 8.5e-238 norM V Multidrug efflux pump
LHPNHANK_00693 8.6e-148 K sequence-specific DNA binding
LHPNHANK_00694 1.5e-142 V (ABC) transporter
LHPNHANK_00695 2.7e-118 V (ABC) transporter
LHPNHANK_00696 4.5e-59 pdxH S pyridoxamine 5'-phosphate oxidase
LHPNHANK_00697 3.8e-224 pbuX F xanthine permease
LHPNHANK_00698 2.5e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LHPNHANK_00699 5.4e-124 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LHPNHANK_00700 2.2e-147 T Histidine kinase
LHPNHANK_00701 1.1e-133 macB2 V ABC transporter, ATP-binding protein
LHPNHANK_00702 0.0 V ABC transporter (permease)
LHPNHANK_00703 8.8e-92 XK27_05000 S metal cluster binding
LHPNHANK_00704 2.2e-29 liaI KT membrane
LHPNHANK_00705 1.3e-16 liaI KT membrane
LHPNHANK_00706 4.1e-156 XK27_09825 V abc transporter atp-binding protein
LHPNHANK_00707 1.2e-116 yvfS V Transporter
LHPNHANK_00708 4.4e-82 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
LHPNHANK_00709 3.3e-164 yocS S Transporter
LHPNHANK_00712 4.1e-156 XK27_09825 V 'abc transporter, ATP-binding protein
LHPNHANK_00713 2e-132 yvfS V ABC-2 type transporter
LHPNHANK_00714 1.1e-187 desK 2.7.13.3 T Histidine kinase
LHPNHANK_00715 2.6e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LHPNHANK_00716 6.1e-185 S AAA domain, putative AbiEii toxin, Type IV TA system
LHPNHANK_00717 1.2e-141 S ABC-2 family transporter protein
LHPNHANK_00718 4.6e-143 S ABC-2 family transporter protein
LHPNHANK_00719 3.4e-77 yfiQ K Acetyltransferase (GNAT) domain
LHPNHANK_00720 0.0 prtA 3.2.1.23 O Belongs to the peptidase S8 family
LHPNHANK_00721 3e-50 ywrO S general stress protein
LHPNHANK_00722 1.1e-151 K sequence-specific DNA binding
LHPNHANK_00723 7.8e-97 S ABC-2 family transporter protein
LHPNHANK_00724 8.9e-153 V ABC transporter, ATP-binding protein
LHPNHANK_00725 4.2e-164 K sequence-specific DNA binding
LHPNHANK_00726 4e-79 3.4.21.89 S RDD family
LHPNHANK_00727 3.8e-78 mutT 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
LHPNHANK_00728 2.1e-151 S Protein of unknown function DUF262
LHPNHANK_00729 2e-202 S Protein of unknown function DUF262
LHPNHANK_00730 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
LHPNHANK_00731 1.5e-147 sdaAA 4.3.1.17 E L-serine dehydratase
LHPNHANK_00732 2.5e-121 sdaAB 4.3.1.17 E L-serine dehydratase
LHPNHANK_00733 8.5e-125 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
LHPNHANK_00734 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LHPNHANK_00735 2.4e-270 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LHPNHANK_00736 1.1e-89 pat 2.3.1.183 M acetyltransferase
LHPNHANK_00737 6.1e-296 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LHPNHANK_00738 4.8e-122 alkD L Dna alkylation repair
LHPNHANK_00740 6.2e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LHPNHANK_00741 5.1e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LHPNHANK_00742 2.5e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LHPNHANK_00743 0.0 smc D Required for chromosome condensation and partitioning
LHPNHANK_00744 3.6e-78 S Protein of unknown function (DUF3278)
LHPNHANK_00745 2.3e-22 WQ51_00220 K Helix-turn-helix domain
LHPNHANK_00746 6.6e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LHPNHANK_00747 3.5e-91 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LHPNHANK_00748 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LHPNHANK_00750 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
LHPNHANK_00751 2.1e-238 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LHPNHANK_00753 1.8e-84 S ECF-type riboflavin transporter, S component
LHPNHANK_00754 4.4e-155 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
LHPNHANK_00755 4.3e-84 XK27_01265 S ECF-type riboflavin transporter, S component
LHPNHANK_00756 3.3e-294 yfmM S abc transporter atp-binding protein
LHPNHANK_00757 4.1e-256 noxE P NADH oxidase
LHPNHANK_00758 6.9e-234 L Transposase
LHPNHANK_00759 4.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
LHPNHANK_00760 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LHPNHANK_00761 9.3e-133 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
LHPNHANK_00762 2e-70 yaeR E COG0346 Lactoylglutathione lyase and related lyases
LHPNHANK_00763 7.6e-164 ypuA S secreted protein
LHPNHANK_00764 9.5e-98 mntH P Mn2 and Fe2 transporters of the NRAMP family
LHPNHANK_00765 4.4e-115 mntH P Mn2 and Fe2 transporters of the NRAMP family
LHPNHANK_00766 4.4e-45 rpmE2 J 50S ribosomal protein L31
LHPNHANK_00767 3.4e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
LHPNHANK_00768 2.9e-176 nrnA 3.1.13.3, 3.1.3.7 S domain protein
LHPNHANK_00769 2.7e-151 gst O Glutathione S-transferase
LHPNHANK_00770 1.1e-184 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LHPNHANK_00771 7.3e-109 tdk 2.7.1.21 F thymidine kinase
LHPNHANK_00772 3.6e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LHPNHANK_00773 1.7e-143 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LHPNHANK_00774 3.6e-103 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LHPNHANK_00775 2.7e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LHPNHANK_00776 4.2e-178 ndpA S 37-kD nucleoid-associated bacterial protein
LHPNHANK_00777 1.9e-99 pvaA M lytic transglycosylase activity
LHPNHANK_00778 2.5e-290 yfiB1 V abc transporter atp-binding protein
LHPNHANK_00779 0.0 XK27_10035 V abc transporter atp-binding protein
LHPNHANK_00780 1.3e-298 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LHPNHANK_00781 1.7e-237 dltB M Membrane protein involved in D-alanine export
LHPNHANK_00782 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LHPNHANK_00783 7.9e-246 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LHPNHANK_00784 0.0 3.6.3.8 P cation transport ATPase
LHPNHANK_00785 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
LHPNHANK_00787 4.6e-193 L PFAM Integrase, catalytic core
LHPNHANK_00788 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LHPNHANK_00789 3.3e-166 metF 1.5.1.20 E reductase
LHPNHANK_00790 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
LHPNHANK_00791 3.8e-91 panT S Psort location CytoplasmicMembrane, score
LHPNHANK_00792 2.4e-93 panT S ECF transporter, substrate-specific component
LHPNHANK_00793 3.3e-92 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LHPNHANK_00794 9.3e-116 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
LHPNHANK_00795 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
LHPNHANK_00796 2.1e-120 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LHPNHANK_00797 1.9e-240 T PhoQ Sensor
LHPNHANK_00798 1e-29 rpsT J Binds directly to 16S ribosomal RNA
LHPNHANK_00799 4e-170 coaA 2.7.1.33 F Pantothenic acid kinase
LHPNHANK_00800 8.3e-105 rsmC 2.1.1.172 J Methyltransferase small domain protein
LHPNHANK_00801 1.1e-231 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
LHPNHANK_00802 3.9e-108 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LHPNHANK_00803 2.8e-64 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
LHPNHANK_00804 1.1e-192 tcsA S membrane
LHPNHANK_00805 1.4e-281 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
LHPNHANK_00806 8.6e-177 yufP S Belongs to the binding-protein-dependent transport system permease family
LHPNHANK_00807 1.2e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
LHPNHANK_00808 4e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
LHPNHANK_00809 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
LHPNHANK_00810 1.1e-81 ypmB S Protein conserved in bacteria
LHPNHANK_00811 1.1e-212 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
LHPNHANK_00812 2.4e-261 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
LHPNHANK_00813 9.7e-20
LHPNHANK_00814 8.6e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
LHPNHANK_00815 1.2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LHPNHANK_00816 9.7e-82 queD 4.1.2.50, 4.2.3.12 H synthase
LHPNHANK_00817 5.1e-133 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
LHPNHANK_00818 2.5e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
LHPNHANK_00819 7.3e-201 D nuclear chromosome segregation
LHPNHANK_00820 3.7e-137 yejC S cyclic nucleotide-binding protein
LHPNHANK_00821 7e-164 rapZ S Displays ATPase and GTPase activities
LHPNHANK_00822 1.4e-181 ybhK S Required for morphogenesis under gluconeogenic growth conditions
LHPNHANK_00823 5.7e-161 whiA K May be required for sporulation
LHPNHANK_00824 1.1e-275 pepD E Dipeptidase
LHPNHANK_00825 9.3e-147 XK27_10720 D peptidase activity
LHPNHANK_00826 4.7e-293 adcA P Belongs to the bacterial solute-binding protein 9 family
LHPNHANK_00827 2.6e-09
LHPNHANK_00829 7.4e-170 yeiH S Membrane
LHPNHANK_00830 1.3e-128 mur1 3.4.17.14, 3.5.1.28 NU muramidase
LHPNHANK_00831 2.9e-165 cpsY K Transcriptional regulator
LHPNHANK_00832 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LHPNHANK_00833 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
LHPNHANK_00834 1.4e-105 artQ P ABC transporter (Permease
LHPNHANK_00835 2.4e-110 glnQ 3.6.3.21 E abc transporter atp-binding protein
LHPNHANK_00836 4.6e-157 aatB ET ABC transporter substrate-binding protein
LHPNHANK_00837 5.2e-270 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LHPNHANK_00838 6.4e-50
LHPNHANK_00839 2.1e-45
LHPNHANK_00840 4.2e-189 adhP 1.1.1.1 C alcohol dehydrogenase
LHPNHANK_00841 2.9e-162 V AAA domain, putative AbiEii toxin, Type IV TA system
LHPNHANK_00842 2.4e-56 S ABC-2 type transporter
LHPNHANK_00843 3.7e-97
LHPNHANK_00844 2.3e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
LHPNHANK_00845 1e-125 gntR1 K transcriptional
LHPNHANK_00846 2e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LHPNHANK_00847 1e-274 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LHPNHANK_00848 2.7e-86
LHPNHANK_00849 2.7e-91 niaR S small molecule binding protein (contains 3H domain)
LHPNHANK_00850 1.3e-128 K DNA-binding helix-turn-helix protein
LHPNHANK_00851 2.1e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LHPNHANK_00852 8.5e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LHPNHANK_00853 1.7e-160 GK ROK family
LHPNHANK_00854 2.5e-155 dprA LU DNA protecting protein DprA
LHPNHANK_00855 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LHPNHANK_00856 2.3e-82 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
LHPNHANK_00857 1.3e-51 V ABC-2 family transporter protein
LHPNHANK_00859 2e-149 S TraX protein
LHPNHANK_00860 1.5e-118 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LHPNHANK_00861 4.7e-236 T PhoQ Sensor
LHPNHANK_00862 1.1e-258 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LHPNHANK_00863 2.7e-224 XK27_05470 E Methionine synthase
LHPNHANK_00864 1.8e-50 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
LHPNHANK_00865 2.8e-252 V Glucan-binding protein C
LHPNHANK_00866 1.5e-121 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LHPNHANK_00867 3.9e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
LHPNHANK_00868 5.5e-95 S Protein of unknown function (DUF1697)
LHPNHANK_00869 2.9e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LHPNHANK_00870 1.4e-181 clcA_2 P Chloride transporter, ClC family
LHPNHANK_00871 5.8e-137 yfeJ 6.3.5.2 F glutamine amidotransferase
LHPNHANK_00872 4e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
LHPNHANK_00873 1e-20 L the current gene model (or a revised gene model) may contain a frame shift
LHPNHANK_00875 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LHPNHANK_00878 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
LHPNHANK_00879 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
LHPNHANK_00880 1.6e-41 C Pyridoxamine 5'-phosphate oxidase
LHPNHANK_00881 3.4e-96 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
LHPNHANK_00882 5e-78 S Macro domain
LHPNHANK_00883 6.2e-68 mgrA K Transcriptional regulator, MarR family
LHPNHANK_00884 8.2e-146 1.6.5.2 GM NmrA-like family
LHPNHANK_00885 2.7e-129 proV E abc transporter atp-binding protein
LHPNHANK_00886 2.5e-262 proWX P ABC transporter
LHPNHANK_00887 1.1e-107 magIII L Base excision DNA repair protein, HhH-GPD family
LHPNHANK_00888 2.3e-32 L Integrase core domain protein
LHPNHANK_00889 0.0 V ABC transporter (Permease
LHPNHANK_00890 8.6e-125 V abc transporter atp-binding protein
LHPNHANK_00891 1.1e-92 tetR K transcriptional regulator
LHPNHANK_00892 1.9e-141 S Phenazine biosynthesis protein
LHPNHANK_00893 4.1e-91 2.7.7.65 T Psort location CytoplasmicMembrane, score
LHPNHANK_00894 1.4e-131 cbiQ P cobalt transport
LHPNHANK_00895 1e-156 P abc transporter atp-binding protein
LHPNHANK_00896 9.1e-147 cbiO2 P ABC transporter, ATP-binding protein
LHPNHANK_00897 2.9e-122 L Helix-turn-helix domain
LHPNHANK_00898 3.7e-141 L Integrase core domain protein
LHPNHANK_00899 6e-76 tnp L DDE domain
LHPNHANK_00900 2.5e-32 pnuC H nicotinamide mononucleotide transporter
LHPNHANK_00901 9.8e-13
LHPNHANK_00902 1e-68 S Protein of unknown function with HXXEE motif
LHPNHANK_00903 2.9e-96 K Transcriptional regulator, TetR family
LHPNHANK_00904 3.3e-153 czcD P cation diffusion facilitator family transporter
LHPNHANK_00905 1.9e-195 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
LHPNHANK_00906 1.5e-186 adhB 1.1.1.1, 1.1.1.14 E Zinc-binding dehydrogenase
LHPNHANK_00907 3.3e-42 2.4.2.3 F Phosphorylase superfamily
LHPNHANK_00908 8.3e-111 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
LHPNHANK_00909 1.4e-150 S von Willebrand factor (vWF) type A domain
LHPNHANK_00910 4.6e-193 L PFAM Integrase, catalytic core
LHPNHANK_00911 1.8e-181 yclQ P ABC-type enterochelin transport system, periplasmic component
LHPNHANK_00912 9.6e-234 dinF V Mate efflux family protein
LHPNHANK_00913 4.3e-270 S Psort location CytoplasmicMembrane, score
LHPNHANK_00914 5.1e-309 FbpA K RNA-binding protein homologous to eukaryotic snRNP
LHPNHANK_00915 1e-142 S TraX protein
LHPNHANK_00916 1.2e-94 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
LHPNHANK_00917 3.5e-146 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
LHPNHANK_00918 4.5e-177 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LHPNHANK_00919 4.5e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LHPNHANK_00920 4.4e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LHPNHANK_00921 1.1e-240 nylA 3.5.1.4 J Belongs to the amidase family
LHPNHANK_00922 3.9e-148 yckB ET Belongs to the bacterial solute-binding protein 3 family
LHPNHANK_00923 6.4e-82 yecS P ABC transporter (Permease
LHPNHANK_00924 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
LHPNHANK_00925 1.1e-169 bglC K Transcriptional regulator
LHPNHANK_00926 1.2e-244 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LHPNHANK_00927 6.9e-240 agcS E (Alanine) symporter
LHPNHANK_00928 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
LHPNHANK_00929 5.6e-239 metY 2.5.1.49 E o-acetylhomoserine
LHPNHANK_00930 1.9e-88 L COG1943 Transposase and inactivated derivatives
LHPNHANK_00931 2.9e-122 L Helix-turn-helix domain
LHPNHANK_00932 3.7e-141 L Integrase core domain protein
LHPNHANK_00933 3.8e-93 S haloacid dehalogenase-like hydrolase
LHPNHANK_00934 9.4e-86 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LHPNHANK_00935 6.2e-111 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
LHPNHANK_00936 6.1e-35 M1-755 P Hemerythrin HHE cation binding domain protein
LHPNHANK_00937 2.1e-241 XK27_04775 S hemerythrin HHE cation binding domain
LHPNHANK_00938 6.2e-146 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LHPNHANK_00939 1.1e-172 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
LHPNHANK_00940 1.6e-70 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LHPNHANK_00941 5.1e-44 yktA S Belongs to the UPF0223 family
LHPNHANK_00942 6.5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
LHPNHANK_00943 1.4e-250 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
LHPNHANK_00944 1.2e-155 pstS P phosphate
LHPNHANK_00945 1.9e-156 pstC P probably responsible for the translocation of the substrate across the membrane
LHPNHANK_00946 1.5e-155 pstA P phosphate transport system permease
LHPNHANK_00947 4e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LHPNHANK_00948 2.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LHPNHANK_00949 3.2e-113 phoU P Plays a role in the regulation of phosphate uptake
LHPNHANK_00950 0.0 pepN 3.4.11.2 E aminopeptidase
LHPNHANK_00951 6e-194 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
LHPNHANK_00952 1.9e-186 lplA 6.3.1.20 H Lipoate-protein ligase
LHPNHANK_00953 2.8e-40
LHPNHANK_00954 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
LHPNHANK_00955 7.8e-301 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
LHPNHANK_00956 6.2e-177 malR K Transcriptional regulator
LHPNHANK_00957 2.5e-228 malX G ABC transporter
LHPNHANK_00958 3.3e-250 malF P ABC transporter (Permease
LHPNHANK_00959 9.8e-152 malG P ABC transporter (Permease
LHPNHANK_00960 1.4e-212 msmX P Belongs to the ABC transporter superfamily
LHPNHANK_00961 3e-24 tatA U protein secretion
LHPNHANK_00962 1.2e-118 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LHPNHANK_00963 3e-285 ywbL P COG0672 High-affinity Fe2 Pb2 permease
LHPNHANK_00964 6.9e-231 ycdB P peroxidase
LHPNHANK_00965 4.9e-146 ycdO P periplasmic lipoprotein involved in iron transport
LHPNHANK_00966 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
LHPNHANK_00967 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
LHPNHANK_00968 0.0 lpdA 1.8.1.4 C Dehydrogenase
LHPNHANK_00969 9.6e-213 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LHPNHANK_00970 1.9e-181 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LHPNHANK_00971 7.8e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
LHPNHANK_00972 1.1e-215 hpk9 2.7.13.3 T protein histidine kinase activity
LHPNHANK_00973 5.4e-234 2.7.13.3 T protein histidine kinase activity
LHPNHANK_00974 0.0 S the current gene model (or a revised gene model) may contain a frame shift
LHPNHANK_00975 1.7e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LHPNHANK_00976 3.8e-119 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LHPNHANK_00977 1.5e-217 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LHPNHANK_00978 4.8e-249 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
LHPNHANK_00979 5.5e-181 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
LHPNHANK_00980 1e-156 rssA S Phospholipase, patatin family
LHPNHANK_00981 1.3e-103 estA E Lysophospholipase L1 and related esterases
LHPNHANK_00982 8.8e-287 S unusual protein kinase
LHPNHANK_00983 4.9e-39 S granule-associated protein
LHPNHANK_00984 4.3e-288 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LHPNHANK_00985 2.7e-197 S hmm pf01594
LHPNHANK_00986 4e-107 G Belongs to the phosphoglycerate mutase family
LHPNHANK_00987 4.1e-107 G Belongs to the phosphoglycerate mutase family
LHPNHANK_00988 1.1e-107 pgm G Belongs to the phosphoglycerate mutase family
LHPNHANK_00989 1.4e-150 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
LHPNHANK_00990 2.2e-244 S Polysaccharide biosynthesis protein
LHPNHANK_00991 0.0 M Polysaccharide biosynthesis protein
LHPNHANK_00992 5.3e-206 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LHPNHANK_00993 1e-170 S glycosyl transferase family 2
LHPNHANK_00994 4e-85
LHPNHANK_00995 2e-205 M glycosyl transferase group 1
LHPNHANK_00996 1.1e-164 S Glycosyl transferase family 2
LHPNHANK_00997 5.1e-161 licD M LICD family
LHPNHANK_00998 4.3e-127 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
LHPNHANK_00999 1.3e-257 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
LHPNHANK_01000 6.1e-113 cpsD D COG0489 ATPases involved in chromosome partitioning
LHPNHANK_01001 7.2e-116 cps4C M biosynthesis protein
LHPNHANK_01002 3.5e-137 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
LHPNHANK_01003 8e-242 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
LHPNHANK_01004 3.2e-141 L PFAM transposase IS116 IS110 IS902 family
LHPNHANK_01005 2.7e-64 L Transposase (IS116 IS110 IS902 family)
LHPNHANK_01006 3.1e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
LHPNHANK_01007 3.3e-277 pepV 3.5.1.18 E Dipeptidase
LHPNHANK_01008 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
LHPNHANK_01009 4.9e-93 yybC
LHPNHANK_01010 1.4e-86 XK27_03610 K Gnat family
LHPNHANK_01011 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LHPNHANK_01012 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
LHPNHANK_01013 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LHPNHANK_01014 3.6e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
LHPNHANK_01015 5.6e-17 M LysM domain
LHPNHANK_01016 1.5e-86 ebsA S Family of unknown function (DUF5322)
LHPNHANK_01017 1.4e-223 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
LHPNHANK_01018 0.0 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
LHPNHANK_01019 1.2e-97 lepB 3.4.21.89 U Belongs to the peptidase S26 family
LHPNHANK_01020 8.3e-224 G COG0457 FOG TPR repeat
LHPNHANK_01021 4.3e-177 yubA S permease
LHPNHANK_01022 1.9e-91 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
LHPNHANK_01023 7.3e-164 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
LHPNHANK_01024 3.2e-124 ftsE D cell division ATP-binding protein FtsE
LHPNHANK_01025 5.7e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LHPNHANK_01026 6.6e-204 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LHPNHANK_01027 6.8e-153 yjjH S Calcineurin-like phosphoesterase
LHPNHANK_01028 1.4e-133 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
LHPNHANK_01029 0.0 pacL 3.6.3.8 P cation transport ATPase
LHPNHANK_01030 5.3e-68 ywiB S Domain of unknown function (DUF1934)
LHPNHANK_01031 3.2e-141 XK27_00120 2.4.2.3 F Phosphorylase superfamily
LHPNHANK_01032 1.7e-159 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
LHPNHANK_01033 2e-146 yidA S hydrolases of the HAD superfamily
LHPNHANK_01034 4.1e-207 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
LHPNHANK_01035 2.9e-122 L Helix-turn-helix domain
LHPNHANK_01036 3.7e-141 L Integrase core domain protein
LHPNHANK_01037 5.2e-77 L COG1943 Transposase and inactivated derivatives
LHPNHANK_01038 1.5e-56 S Protein of unknown function (DUF454)
LHPNHANK_01039 4.6e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
LHPNHANK_01040 1e-235 vicK 2.7.13.3 T Histidine kinase
LHPNHANK_01041 3.8e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LHPNHANK_01042 2.7e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
LHPNHANK_01043 6.1e-146 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
LHPNHANK_01044 1.9e-116 gltJ P ABC transporter (Permease
LHPNHANK_01045 2.9e-111 tcyB_2 P ABC transporter (permease)
LHPNHANK_01046 2.7e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
LHPNHANK_01047 1.7e-143 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
LHPNHANK_01048 1.9e-116 gltJ P ABC transporter (Permease
LHPNHANK_01049 2.9e-111 tcyB_2 P ABC transporter (permease)
LHPNHANK_01050 8.5e-154 endA F DNA RNA non-specific endonuclease
LHPNHANK_01051 7.2e-26 epuA S DNA-directed RNA polymerase subunit beta
LHPNHANK_01052 2e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LHPNHANK_01054 2e-208 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
LHPNHANK_01055 5.5e-250 ydaM M Glycosyltransferases, probably involved in cell wall biogenesis
LHPNHANK_01057 3.2e-136
LHPNHANK_01058 1.1e-214 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LHPNHANK_01059 4.6e-193 L PFAM Integrase, catalytic core
LHPNHANK_01060 9.2e-212 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LHPNHANK_01061 3.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LHPNHANK_01062 2.7e-302 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LHPNHANK_01063 1.5e-86 ytsP 1.8.4.14 T GAF domain-containing protein
LHPNHANK_01064 6e-163 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LHPNHANK_01065 6.5e-21 WQ51_02665 S Protein of unknown function (DUF3042)
LHPNHANK_01066 6.6e-08
LHPNHANK_01067 4.8e-131 K cell adhesion
LHPNHANK_01069 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LHPNHANK_01070 2.1e-211 XK27_05110 P Chloride transporter ClC family
LHPNHANK_01071 1.9e-40 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
LHPNHANK_01072 3.3e-278 clcA P Chloride transporter, ClC family
LHPNHANK_01073 1e-75 fld C Flavodoxin
LHPNHANK_01074 1.1e-17 XK27_08880
LHPNHANK_01075 1.6e-126 XK27_08875 O Zinc-dependent metalloprotease
LHPNHANK_01076 9.5e-149 estA CE1 S Esterase
LHPNHANK_01077 6e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LHPNHANK_01078 3.1e-136 XK27_08845 S abc transporter atp-binding protein
LHPNHANK_01079 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
LHPNHANK_01080 3.6e-177 XK27_08835 S ABC transporter substrate binding protein
LHPNHANK_01081 3.8e-18 S Domain of unknown function (DUF4649)
LHPNHANK_01082 3.4e-29 L COG1943 Transposase and inactivated derivatives
LHPNHANK_01083 2.7e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
LHPNHANK_01084 5.1e-187 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LHPNHANK_01085 0.0 dnaE 2.7.7.7 L DNA polymerase
LHPNHANK_01086 5.9e-111 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LHPNHANK_01087 3.1e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LHPNHANK_01088 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
LHPNHANK_01089 4.2e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LHPNHANK_01090 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LHPNHANK_01091 6.2e-179 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
LHPNHANK_01093 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LHPNHANK_01094 1.2e-95 ypmS S Protein conserved in bacteria
LHPNHANK_01095 2.2e-162 ypmR E COG2755 Lysophospholipase L1 and related esterases
LHPNHANK_01096 2e-144 DegV S DegV family
LHPNHANK_01097 6e-302 recN L May be involved in recombinational repair of damaged DNA
LHPNHANK_01098 8.3e-73 argR K Regulates arginine biosynthesis genes
LHPNHANK_01099 4.2e-147 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
LHPNHANK_01100 1.7e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LHPNHANK_01101 3.5e-29 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LHPNHANK_01102 4.6e-236 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LHPNHANK_01103 6e-07 KT response to antibiotic
LHPNHANK_01104 1.7e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LHPNHANK_01105 1.3e-125 dnaD
LHPNHANK_01106 2.7e-182 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LHPNHANK_01107 1.1e-92 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LHPNHANK_01108 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
LHPNHANK_01109 2.1e-67 GnaT 2.5.1.16 K acetyltransferase
LHPNHANK_01110 3.1e-136 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
LHPNHANK_01111 3.5e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LHPNHANK_01112 6.9e-113 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
LHPNHANK_01113 9.3e-245 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LHPNHANK_01114 4.6e-226 rodA D Belongs to the SEDS family
LHPNHANK_01115 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
LHPNHANK_01116 4.3e-236 L Transposase
LHPNHANK_01117 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
LHPNHANK_01118 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
LHPNHANK_01119 8e-180 XK27_08075 M glycosyl transferase family 2
LHPNHANK_01120 5.5e-85 S Carbohydrate-binding domain-containing protein Cthe_2159
LHPNHANK_01121 4.6e-143 P molecular chaperone
LHPNHANK_01122 1.4e-92 XK27_05505 S Psort location CytoplasmicMembrane, score
LHPNHANK_01125 4.1e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
LHPNHANK_01126 8e-60 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LHPNHANK_01127 2.8e-137 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
LHPNHANK_01128 3.1e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LHPNHANK_01129 2.3e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LHPNHANK_01130 1.1e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
LHPNHANK_01131 1.6e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LHPNHANK_01132 5.5e-118 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
LHPNHANK_01133 6.5e-179 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LHPNHANK_01134 1.9e-192 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LHPNHANK_01135 4.1e-60 XK27_08085
LHPNHANK_01136 1.4e-146 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
LHPNHANK_01137 4e-33
LHPNHANK_01138 6.3e-219 V MatE
LHPNHANK_01139 9.3e-138 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
LHPNHANK_01140 6.5e-119 ylfI S tigr01906
LHPNHANK_01141 4e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LHPNHANK_01142 5.3e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
LHPNHANK_01143 7.7e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
LHPNHANK_01144 2.2e-30 KT response to antibiotic
LHPNHANK_01146 1.3e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LHPNHANK_01147 2.7e-111 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
LHPNHANK_01148 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LHPNHANK_01149 4.3e-258 S phospholipase Carboxylesterase
LHPNHANK_01150 8.2e-199 yurR 1.4.5.1 E oxidoreductase
LHPNHANK_01151 4e-145 zupT P Mediates zinc uptake. May also transport other divalent cations
LHPNHANK_01152 7.1e-144 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LHPNHANK_01153 1.7e-117 trmK 2.1.1.217 S SAM-dependent methyltransferase
LHPNHANK_01154 1.3e-64 gtrA S GtrA-like protein
LHPNHANK_01155 9.7e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LHPNHANK_01156 2.5e-167 ybbR S Protein conserved in bacteria
LHPNHANK_01157 2e-147 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LHPNHANK_01158 2.6e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
LHPNHANK_01159 2.3e-150 cobQ S glutamine amidotransferase
LHPNHANK_01160 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LHPNHANK_01161 2e-132 pip 1.11.1.10 S Alpha beta hydrolase
LHPNHANK_01162 1.6e-39 MA20_06245 S yiaA/B two helix domain
LHPNHANK_01163 0.0 uup S abc transporter atp-binding protein
LHPNHANK_01164 3.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
LHPNHANK_01165 5.5e-179 yfmL 3.6.4.13 L DEAD DEAH box helicase
LHPNHANK_01166 9.9e-227 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
LHPNHANK_01167 2.7e-153 XK27_05675 S Esterase
LHPNHANK_01168 6.1e-162 XK27_05670 S Putative esterase
LHPNHANK_01169 1.1e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
LHPNHANK_01170 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LHPNHANK_01171 3e-38 ptsH G phosphocarrier protein Hpr
LHPNHANK_01172 3.9e-223 icd 1.1.1.42 C Isocitrate dehydrogenase
LHPNHANK_01173 2.5e-211 citZ 2.3.3.1 C Belongs to the citrate synthase family
LHPNHANK_01174 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LHPNHANK_01175 2.2e-34 nrdH O Glutaredoxin
LHPNHANK_01176 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LHPNHANK_01177 3.8e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LHPNHANK_01178 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LHPNHANK_01179 8.4e-138 divIVA D Cell division initiation protein
LHPNHANK_01180 1.9e-144 ylmH S conserved protein, contains S4-like domain
LHPNHANK_01181 6.5e-30 yggT D integral membrane protein
LHPNHANK_01182 3.2e-101 sepF D cell septum assembly
LHPNHANK_01183 6e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LHPNHANK_01184 1.7e-238 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LHPNHANK_01185 7.1e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LHPNHANK_01186 2.2e-133 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LHPNHANK_01187 5.6e-200 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LHPNHANK_01188 1e-251 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LHPNHANK_01190 0.0 typA T GTP-binding protein TypA
LHPNHANK_01191 1.9e-178 glk 2.7.1.2 G Glucokinase
LHPNHANK_01192 2.4e-27 yqgQ S protein conserved in bacteria
LHPNHANK_01193 5.2e-83 perR P Belongs to the Fur family
LHPNHANK_01194 9.3e-92 dps P Belongs to the Dps family
LHPNHANK_01195 1.7e-114 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
LHPNHANK_01196 3.1e-171 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
LHPNHANK_01197 9.4e-112 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
LHPNHANK_01198 1.3e-185 holA 2.7.7.7 L DNA polymerase III delta subunit
LHPNHANK_01199 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LHPNHANK_01200 1.8e-63 S Domain of unknown function (DUF4430)
LHPNHANK_01201 6.7e-73 S Psort location CytoplasmicMembrane, score
LHPNHANK_01202 6e-129 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
LHPNHANK_01203 2.1e-133 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
LHPNHANK_01204 9.3e-167 sitA P Belongs to the bacterial solute-binding protein 9 family
LHPNHANK_01205 3.6e-117 sirR K iron dependent repressor
LHPNHANK_01206 2.1e-131 htpX O Belongs to the peptidase M48B family
LHPNHANK_01207 7.7e-92 lemA S LemA family
LHPNHANK_01208 6e-172 spd F DNA RNA non-specific endonuclease
LHPNHANK_01209 0.0 2.4.1.21 GT5 M Right handed beta helix region
LHPNHANK_01210 1.9e-132 S double-stranded DNA endodeoxyribonuclease activity
LHPNHANK_01211 2.7e-172 hsdM 2.1.1.72 V type I restriction-modification system
LHPNHANK_01212 8.4e-255 L overlaps another CDS with the same product name
LHPNHANK_01213 7.6e-297 L overlaps another CDS with the same product name
LHPNHANK_01214 7.3e-308 L overlaps another CDS with the same product name
LHPNHANK_01215 4.5e-18
LHPNHANK_01216 2.9e-122 L Helix-turn-helix domain
LHPNHANK_01217 3.7e-141 L Integrase core domain protein
LHPNHANK_01218 2.1e-125 racA K helix_turn_helix, mercury resistance
LHPNHANK_01219 7.2e-39
LHPNHANK_01220 1.3e-237 L Transposase
LHPNHANK_01221 3.6e-16
LHPNHANK_01222 2.1e-134 ksgA 2.1.1.182, 2.1.1.184 J Ribosomal RNA adenine dimethylase
LHPNHANK_01223 4.3e-22 K Replication initiation factor
LHPNHANK_01224 3e-234 K Replication initiation factor
LHPNHANK_01225 3.7e-265 D Domain of unknown function DUF87
LHPNHANK_01226 1e-63 S Bacterial protein of unknown function (DUF961)
LHPNHANK_01227 2.3e-53 S Bacterial protein of unknown function (DUF961)
LHPNHANK_01229 7.5e-96 P ABC-2 family transporter protein
LHPNHANK_01230 3.7e-154 V abc transporter atp-binding protein
LHPNHANK_01231 1.2e-59 K GntR family transcriptional regulator
LHPNHANK_01232 1.3e-67 K DNA-templated transcription, initiation
LHPNHANK_01233 7.5e-42 K DNA-binding transcription factor activity
LHPNHANK_01234 2.7e-58 S the current gene model (or a revised gene model) may contain a frame shift
LHPNHANK_01235 3.8e-238 U Relaxase/Mobilisation nuclease domain
LHPNHANK_01236 9.9e-241 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
LHPNHANK_01237 5.6e-219 L Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
LHPNHANK_01238 1e-181 L HaeIII restriction endonuclease
LHPNHANK_01239 3.4e-199 haeIIIM 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
LHPNHANK_01240 3e-31 K Transcriptional regulator
LHPNHANK_01241 2e-107 L Psort location Cytoplasmic, score
LHPNHANK_01242 0.0 L the current gene model (or a revised gene model) may contain a
LHPNHANK_01243 3.5e-152 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
LHPNHANK_01244 6.8e-301 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LHPNHANK_01245 1.3e-120 traB S Domain of unknown function (DUF4366)
LHPNHANK_01246 5.5e-12
LHPNHANK_01247 0.0 M this gene contains a nucleotide ambiguity which may be the result of a sequencing error
LHPNHANK_01248 0.0 U AAA-like domain
LHPNHANK_01249 2.8e-64 S PrgI family protein
LHPNHANK_01250 1.1e-40
LHPNHANK_01251 2.3e-151
LHPNHANK_01252 1.6e-29 S Maff2 family
LHPNHANK_01253 1.4e-50 L single-stranded DNA binding
LHPNHANK_01254 6.4e-101 K Psort location Cytoplasmic, score
LHPNHANK_01255 0.0 U Type IV secretory system Conjugative DNA transfer
LHPNHANK_01256 9.6e-75 S Protein of unknown function (DUF3801)
LHPNHANK_01257 5.1e-190 ybl78 L Transcriptional regulator
LHPNHANK_01258 1.1e-25
LHPNHANK_01259 8.1e-154 S KilA-N
LHPNHANK_01260 2.8e-124 hsdM 2.1.1.72 V type I restriction-modification system
LHPNHANK_01261 3e-136 S Protein conserved in bacteria
LHPNHANK_01262 1.9e-186 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
LHPNHANK_01263 2.4e-309 S cog cog0433
LHPNHANK_01264 4.9e-254 S SIR2-like domain
LHPNHANK_01265 9.8e-123
LHPNHANK_01266 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
LHPNHANK_01267 1.7e-45 K Helix-turn-helix domain
LHPNHANK_01268 4.4e-45 S Phage derived protein Gp49-like (DUF891)
LHPNHANK_01269 4.6e-132 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
LHPNHANK_01270 2.4e-217 MA20_36090 S Protein of unknown function (DUF2974)
LHPNHANK_01271 1.8e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LHPNHANK_01272 1.7e-159 5.2.1.8 G hydrolase
LHPNHANK_01273 7.8e-27 P Hemerythrin HHE cation binding domain protein
LHPNHANK_01274 5.9e-142 XK27_00880 3.4.17.14, 3.5.1.28 M Glycosyl hydrolase, family 25
LHPNHANK_01275 2.7e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LHPNHANK_01276 6e-117 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
LHPNHANK_01277 5.2e-175 S hydrolase
LHPNHANK_01278 8.4e-23
LHPNHANK_01279 2.1e-137 M LysM domain
LHPNHANK_01280 1.1e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
LHPNHANK_01282 8.7e-235 mntH P H( )-stimulated, divalent metal cation uptake system
LHPNHANK_01283 1.1e-33 XK27_12190 S protein conserved in bacteria
LHPNHANK_01285 2.5e-87 bioY S biotin synthase
LHPNHANK_01286 1.7e-251 yegQ O Peptidase U32
LHPNHANK_01287 1.5e-177 yegQ O Peptidase U32
LHPNHANK_01289 4.6e-193 L PFAM Integrase, catalytic core
LHPNHANK_01290 3e-67 ytxH S General stress protein
LHPNHANK_01291 3.7e-08 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LHPNHANK_01292 1.2e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LHPNHANK_01293 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LHPNHANK_01294 2.2e-41 pspC KT PspC domain
LHPNHANK_01295 4.6e-193 L PFAM Integrase, catalytic core
LHPNHANK_01296 9.3e-85 ydcK S Belongs to the SprT family
LHPNHANK_01297 0.0 yhgF K Transcriptional accessory protein
LHPNHANK_01299 1.6e-155 XK27_03015 S permease
LHPNHANK_01300 4.9e-148 ycgQ S TIGR03943 family
LHPNHANK_01301 4e-290 sulP P Sulfate permease and related transporters (MFS superfamily)
LHPNHANK_01302 7.3e-104
LHPNHANK_01303 2.5e-123 estA E GDSL-like Lipase/Acylhydrolase
LHPNHANK_01304 7.8e-98 S CAAX protease self-immunity
LHPNHANK_01305 5e-52
LHPNHANK_01307 2.4e-62 yqeB S Pyrimidine dimer DNA glycosylase
LHPNHANK_01308 2.4e-60 S Protein of unknown function (DUF1722)
LHPNHANK_01309 2.2e-19 S Bacterial lipoprotein
LHPNHANK_01310 6.8e-11
LHPNHANK_01311 8.6e-123 V CAAX protease self-immunity
LHPNHANK_01312 6.4e-48
LHPNHANK_01313 2.1e-76 K TetR family transcriptional regulator
LHPNHANK_01314 2.9e-81 Q Methyltransferase domain
LHPNHANK_01315 4.6e-131 ybbA S Putative esterase
LHPNHANK_01316 5.1e-171 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
LHPNHANK_01317 5.8e-135 fecE 3.6.3.34 HP ABC transporter
LHPNHANK_01318 6.1e-159 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LHPNHANK_01319 1.4e-128 V CAAX protease self-immunity
LHPNHANK_01320 5.2e-153 S Domain of unknown function (DUF4300)
LHPNHANK_01321 0.0 M family 8
LHPNHANK_01322 3.5e-109 cutC P Participates in the control of copper homeostasis
LHPNHANK_01323 4.8e-65 S CAAX amino terminal protease family
LHPNHANK_01324 2.8e-97 ypgQ F HD superfamily hydrolase
LHPNHANK_01325 3e-96 XK27_08140 K Bacterial regulatory proteins, tetR family
LHPNHANK_01326 5.2e-153 yitS S EDD domain protein, DegV family
LHPNHANK_01327 9.1e-204 yeaN P transporter
LHPNHANK_01328 1.3e-131 S Domain of unknown function (DUF4336)
LHPNHANK_01329 4.4e-130 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LHPNHANK_01330 2.8e-157 K DNA-binding helix-turn-helix protein
LHPNHANK_01331 5.2e-139 S CAAX protease self-immunity
LHPNHANK_01332 7.9e-76 XK27_04435 3.5.4.5 J Acetyltransferase GNAT family
LHPNHANK_01333 6.5e-142 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LHPNHANK_01334 6.9e-96 S HD domain
LHPNHANK_01335 6.1e-252 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LHPNHANK_01336 2e-97 mip S hydroperoxide reductase activity
LHPNHANK_01337 6.5e-201 I acyl-CoA dehydrogenase
LHPNHANK_01338 2.8e-150 ydiA P C4-dicarboxylate transporter malic acid transport
LHPNHANK_01339 1.3e-241 msrR K Transcriptional regulator
LHPNHANK_01340 2.5e-152 pheA 4.2.1.51 E Prephenate dehydratase
LHPNHANK_01341 6.7e-76 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LHPNHANK_01342 8.3e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
LHPNHANK_01343 7e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
LHPNHANK_01344 4.2e-53 yheA S Belongs to the UPF0342 family
LHPNHANK_01345 3.1e-206 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
LHPNHANK_01346 3.8e-218 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LHPNHANK_01347 5.9e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LHPNHANK_01348 4.5e-160 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LHPNHANK_01349 1.5e-118 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
LHPNHANK_01350 3.8e-218 ywbD 2.1.1.191 J Methyltransferase
LHPNHANK_01351 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
LHPNHANK_01352 1.2e-25 WQ51_00785
LHPNHANK_01353 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LHPNHANK_01354 3.3e-77 yueI S Protein of unknown function (DUF1694)
LHPNHANK_01355 3.3e-270 L Transposase
LHPNHANK_01356 8.4e-199 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
LHPNHANK_01357 6.8e-198 yyaQ S YjbR
LHPNHANK_01358 7.1e-181 ccpA K Catabolite control protein A
LHPNHANK_01359 1.6e-210 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
LHPNHANK_01360 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
LHPNHANK_01361 2.1e-276 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LHPNHANK_01362 6.6e-81 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
LHPNHANK_01363 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LHPNHANK_01364 2e-33 secG U Preprotein translocase subunit SecG
LHPNHANK_01365 2.2e-221 mdtG EGP Major facilitator Superfamily
LHPNHANK_01366 5.1e-102 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LHPNHANK_01367 4.1e-150 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LHPNHANK_01368 2.2e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LHPNHANK_01369 2e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
LHPNHANK_01370 4.6e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LHPNHANK_01371 7.1e-150 licT K antiterminator
LHPNHANK_01372 1.7e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LHPNHANK_01373 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
LHPNHANK_01374 3.3e-147 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LHPNHANK_01375 6.9e-153 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LHPNHANK_01376 3.5e-151 I Alpha/beta hydrolase family
LHPNHANK_01377 6.6e-08
LHPNHANK_01378 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
LHPNHANK_01379 1.4e-78 feoA P FeoA domain protein
LHPNHANK_01380 6.4e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
LHPNHANK_01381 5.8e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
LHPNHANK_01382 1e-34 ykuJ S protein conserved in bacteria
LHPNHANK_01383 4.1e-181 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LHPNHANK_01384 0.0 clpE O Belongs to the ClpA ClpB family
LHPNHANK_01385 7.9e-87 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
LHPNHANK_01386 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
LHPNHANK_01387 1.8e-173 S oxidoreductase
LHPNHANK_01388 7.8e-230 murN 2.3.2.16 V FemAB family
LHPNHANK_01389 6.4e-117 M Pfam SNARE associated Golgi protein
LHPNHANK_01390 1.9e-107 S Domain of Unknown Function with PDB structure (DUF3862)
LHPNHANK_01393 2.5e-204 rpsA 1.17.7.4 J ribosomal protein S1
LHPNHANK_01396 3.7e-16 S Protein of unknown function (DUF2969)
LHPNHANK_01397 1.2e-199 ilvE 2.6.1.42 E Aminotransferase
LHPNHANK_01398 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LHPNHANK_01399 1.4e-10
LHPNHANK_01401 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LHPNHANK_01402 1.1e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LHPNHANK_01403 4.8e-13 L Helix-hairpin-helix DNA-binding motif class 1
LHPNHANK_01404 2.2e-30 S Domain of unknown function (DUF1912)
LHPNHANK_01405 4.4e-164 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
LHPNHANK_01406 1.5e-250 mmuP E amino acid
LHPNHANK_01407 3.9e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
LHPNHANK_01408 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LHPNHANK_01409 9.7e-22
LHPNHANK_01410 1.9e-89 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LHPNHANK_01411 2.9e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LHPNHANK_01412 3.1e-212 mvaS 2.3.3.10 I synthase
LHPNHANK_01413 8e-222 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
LHPNHANK_01414 1.9e-77 K hmm pf08876
LHPNHANK_01415 5.2e-119 yqfA K protein, Hemolysin III
LHPNHANK_01416 4.1e-29 pspC KT PspC domain protein
LHPNHANK_01417 6.2e-30 K regulation of RNA biosynthetic process
LHPNHANK_01418 4.6e-193 L PFAM Integrase, catalytic core
LHPNHANK_01419 4e-127 S Belongs to the UPF0255 family
LHPNHANK_01420 3.3e-197 S Protein of unknown function (DUF3114)
LHPNHANK_01421 1.7e-160 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LHPNHANK_01422 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LHPNHANK_01423 2.8e-246 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
LHPNHANK_01424 2.6e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
LHPNHANK_01425 0.0 U protein secretion
LHPNHANK_01426 1.5e-236 L Transposase
LHPNHANK_01427 5.9e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LHPNHANK_01428 2e-26
LHPNHANK_01429 7.7e-97 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
LHPNHANK_01430 3.2e-256 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LHPNHANK_01431 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
LHPNHANK_01432 3.9e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LHPNHANK_01434 1.2e-175 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
LHPNHANK_01435 1.7e-168 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
LHPNHANK_01436 1.4e-135 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
LHPNHANK_01437 1.3e-246 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LHPNHANK_01438 6.3e-124 E alpha/beta hydrolase fold
LHPNHANK_01440 1.5e-89 O stage V sporulation protein K
LHPNHANK_01441 1.2e-11
LHPNHANK_01442 1.6e-197 ald 1.4.1.1 C Belongs to the AlaDH PNT family
LHPNHANK_01444 4.5e-216 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
LHPNHANK_01445 5.3e-136 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LHPNHANK_01446 3.9e-114 S VIT family
LHPNHANK_01447 3.5e-28 deoD_1 2.4.2.3 F Phosphorylase superfamily
LHPNHANK_01448 1.5e-77 deoD_1 2.4.2.3 F Phosphorylase superfamily
LHPNHANK_01449 6.2e-21
LHPNHANK_01450 2.7e-28 XK27_00085 K Transcriptional
LHPNHANK_01451 5.3e-197 yceA S Belongs to the UPF0176 family
LHPNHANK_01452 6.8e-122 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LHPNHANK_01453 9.6e-197 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LHPNHANK_01454 0.0 lmrA V abc transporter atp-binding protein
LHPNHANK_01455 0.0 mdlB V abc transporter atp-binding protein
LHPNHANK_01456 2.5e-273 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
LHPNHANK_01457 8.1e-108 abiGI K Transcriptional regulator, AbiEi antitoxin
LHPNHANK_01458 1.4e-102 XK27_00530 M CHAP domain protein
LHPNHANK_01459 1.3e-65 traG U COG3505 Type IV secretory pathway, VirD4 components
LHPNHANK_01461 2.1e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LHPNHANK_01462 1.9e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LHPNHANK_01463 1e-210 V permease protein
LHPNHANK_01464 6.8e-122 macB V ABC transporter, ATP-binding protein
LHPNHANK_01465 3.4e-180 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LHPNHANK_01466 2.6e-127 2.1.1.223 S Putative SAM-dependent methyltransferase
LHPNHANK_01467 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
LHPNHANK_01468 9.3e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
LHPNHANK_01469 1.3e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
LHPNHANK_01470 1.6e-222 pyrP F uracil Permease
LHPNHANK_01471 4.8e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LHPNHANK_01472 1.1e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LHPNHANK_01473 4.8e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LHPNHANK_01474 1.8e-167 fhuR K transcriptional regulator (lysR family)
LHPNHANK_01476 3.4e-69 K Helix-turn-helix
LHPNHANK_01479 9.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LHPNHANK_01480 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
LHPNHANK_01481 6e-08 uvrX 2.7.7.7 L impB/mucB/samB family
LHPNHANK_01482 1e-243 cycA E permease
LHPNHANK_01483 7.1e-90 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
LHPNHANK_01484 6.2e-24 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
LHPNHANK_01485 1.6e-60 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
LHPNHANK_01486 3.6e-24 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
LHPNHANK_01487 9.2e-34 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
LHPNHANK_01488 6.2e-67 glyQ 6.1.1.14 J Glycyl-tRNA synthetase alpha subunit
LHPNHANK_01489 7.3e-220 S membrane
LHPNHANK_01490 1.7e-210 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
LHPNHANK_01491 1.9e-292 nptA P COG1283 Na phosphate symporter
LHPNHANK_01492 1.4e-113 3.4.17.14, 3.5.1.28 NU amidase activity
LHPNHANK_01493 3.4e-81 S Bacterial inner membrane protein
LHPNHANK_01494 2.5e-144 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
LHPNHANK_01495 4.6e-104 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
LHPNHANK_01496 2.1e-52 glnB K Belongs to the P(II) protein family
LHPNHANK_01497 4.7e-227 amt P Ammonium Transporter
LHPNHANK_01498 6.2e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LHPNHANK_01499 1.2e-54 yabA L Involved in initiation control of chromosome replication
LHPNHANK_01500 2e-133 yaaT S stage 0 sporulation protein
LHPNHANK_01501 1e-159 holB 2.7.7.7 L dna polymerase iii
LHPNHANK_01502 1.2e-109 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LHPNHANK_01504 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LHPNHANK_01505 2.6e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LHPNHANK_01506 1.6e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LHPNHANK_01507 1.5e-215 ftsW D Belongs to the SEDS family
LHPNHANK_01508 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
LHPNHANK_01509 7.9e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LHPNHANK_01510 1.1e-156 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LHPNHANK_01511 2.2e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LHPNHANK_01512 1e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LHPNHANK_01513 1.6e-77 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LHPNHANK_01514 9e-122 atpB C it plays a direct role in the translocation of protons across the membrane
LHPNHANK_01515 2.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LHPNHANK_01516 7.4e-45 femA 2.3.2.10, 2.3.2.16 V FemAB family
LHPNHANK_01517 1e-132 femA 2.3.2.10, 2.3.2.16 V FemAB family
LHPNHANK_01519 1e-57 arsC 1.20.4.1 P Belongs to the ArsC family
LHPNHANK_01520 2e-72 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
LHPNHANK_01521 7.4e-222 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LHPNHANK_01522 1e-104 wecD M Acetyltransferase (GNAT) domain
LHPNHANK_01523 3.9e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LHPNHANK_01524 9.5e-161 GK ROK family
LHPNHANK_01525 1.8e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
LHPNHANK_01526 1.9e-145 XK27_08050 O HflC and HflK could regulate a protease
LHPNHANK_01527 2.8e-204 potD P spermidine putrescine ABC transporter
LHPNHANK_01528 4.7e-132 potC P ABC-type spermidine putrescine transport system, permease component II
LHPNHANK_01529 4.1e-139 potB P ABC-type spermidine putrescine transport system, permease component I
LHPNHANK_01530 5.2e-212 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
LHPNHANK_01531 9.5e-169 murB 1.3.1.98 M cell wall formation
LHPNHANK_01532 4.1e-81 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LHPNHANK_01533 4.5e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LHPNHANK_01534 3.5e-290 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
LHPNHANK_01535 6.5e-145 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LHPNHANK_01536 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
LHPNHANK_01537 0.0 ydaO E amino acid
LHPNHANK_01538 7.9e-238 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
LHPNHANK_01539 1.5e-36 ylqC L Belongs to the UPF0109 family
LHPNHANK_01540 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
LHPNHANK_01542 2.3e-197 2.7.13.3 T GHKL domain
LHPNHANK_01543 2.7e-129 agrA KT phosphorelay signal transduction system
LHPNHANK_01544 6.2e-190 O protein import
LHPNHANK_01545 1.9e-166 tehB 2.1.1.265 PQ tellurite resistance protein tehb
LHPNHANK_01546 2.2e-17 yjdB S Domain of unknown function (DUF4767)
LHPNHANK_01547 1.3e-198 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LHPNHANK_01549 9.1e-158 xth 3.1.11.2 L exodeoxyribonuclease III
LHPNHANK_01550 3.7e-71 S QueT transporter
LHPNHANK_01552 1.3e-171 yfjR K regulation of single-species biofilm formation
LHPNHANK_01554 2.1e-185 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LHPNHANK_01555 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LHPNHANK_01556 1.7e-85 ccl S cog cog4708
LHPNHANK_01557 2.8e-163 rbn E Belongs to the UPF0761 family
LHPNHANK_01558 1.1e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
LHPNHANK_01559 3e-232 ytoI K transcriptional regulator containing CBS domains
LHPNHANK_01560 2.8e-99 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
LHPNHANK_01561 2.6e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LHPNHANK_01562 0.0 comEC S Competence protein ComEC
LHPNHANK_01563 1.2e-94 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
LHPNHANK_01564 9.8e-143 plsC 2.3.1.51 I Acyltransferase
LHPNHANK_01565 1.2e-156 nodB3 G deacetylase
LHPNHANK_01566 5.5e-141 yabB 2.1.1.223 L Methyltransferase
LHPNHANK_01567 7e-43 yazA L endonuclease containing a URI domain
LHPNHANK_01568 2.2e-245 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LHPNHANK_01569 7.4e-153 corA P CorA-like protein
LHPNHANK_01570 2.5e-62 yjqA S Bacterial PH domain
LHPNHANK_01571 7.8e-100 thiT S Thiamine transporter
LHPNHANK_01572 3.3e-158 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
LHPNHANK_01573 5.7e-173 yjbB G Permeases of the major facilitator superfamily
LHPNHANK_01574 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LHPNHANK_01575 4e-116 ywaF S Integral membrane protein (intg_mem_TP0381)
LHPNHANK_01576 1e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LHPNHANK_01577 8.8e-156 cjaA ET ABC transporter substrate-binding protein
LHPNHANK_01578 1.5e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
LHPNHANK_01579 3e-106 P ABC transporter (Permease
LHPNHANK_01580 3e-114 papP P ABC transporter (Permease
LHPNHANK_01581 1.2e-191 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
LHPNHANK_01582 8.6e-57
LHPNHANK_01583 2.2e-83 V ABC transporter
LHPNHANK_01584 2.5e-34 K Transcriptional regulator C-terminal region
LHPNHANK_01585 2.3e-30 copZ 2.7.7.77 P Heavy metal-associated domain protein
LHPNHANK_01586 0.0 copA 3.6.3.54 P P-type ATPase
LHPNHANK_01587 1.8e-72 copY K negative regulation of transcription, DNA-templated
LHPNHANK_01588 6.3e-18
LHPNHANK_01589 1e-172 L Psort location Cytoplasmic, score
LHPNHANK_01590 1.7e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
LHPNHANK_01591 3.4e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
LHPNHANK_01592 1.1e-98 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
LHPNHANK_01593 3.2e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
LHPNHANK_01594 1.5e-178 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LHPNHANK_01595 2.7e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
LHPNHANK_01596 3.1e-256 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LHPNHANK_01597 1.5e-40 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
LHPNHANK_01598 3.5e-120 yujD V ABC transporter
LHPNHANK_01599 0.0 S bacteriocin-associated integral membrane protein
LHPNHANK_01600 5.5e-19 S Bacteriocin (Lactococcin_972)
LHPNHANK_01601 2.9e-58
LHPNHANK_01602 0.0 ctpE P E1-E2 ATPase
LHPNHANK_01603 4e-47
LHPNHANK_01604 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LHPNHANK_01606 3.9e-125 V abc transporter atp-binding protein
LHPNHANK_01607 0.0 V ABC transporter (Permease
LHPNHANK_01608 2.7e-129 K transcriptional regulator, MerR family
LHPNHANK_01609 2.9e-105 dnaQ 2.7.7.7 L DNA polymerase III
LHPNHANK_01610 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
LHPNHANK_01611 2.1e-63 XK27_02560 S cog cog2151
LHPNHANK_01612 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
LHPNHANK_01613 8.8e-223 ytfP S Flavoprotein
LHPNHANK_01615 9e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LHPNHANK_01616 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
LHPNHANK_01617 1.9e-176 ecsB U Bacterial ABC transporter protein EcsB
LHPNHANK_01618 1.4e-130 ecsA V abc transporter atp-binding protein
LHPNHANK_01619 3.9e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
LHPNHANK_01620 9.7e-09
LHPNHANK_01622 1.6e-103
LHPNHANK_01624 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
LHPNHANK_01626 1.6e-44 yoeB S Addiction module toxin, Txe YoeB family
LHPNHANK_01627 3.4e-39 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
LHPNHANK_01628 0.0 hsdR 3.1.21.3 L COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
LHPNHANK_01629 1e-244 D nuclear chromosome segregation
LHPNHANK_01630 3.6e-175
LHPNHANK_01631 1.7e-70 3.1.21.3 V Type I restriction modification DNA specificity domain
LHPNHANK_01632 0.0 2.1.1.72 V type I restriction-modification system
LHPNHANK_01633 9.1e-198 ylbM S Belongs to the UPF0348 family
LHPNHANK_01634 1.3e-139 yqeM Q Methyltransferase domain protein
LHPNHANK_01635 2e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LHPNHANK_01636 1e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
LHPNHANK_01637 1.2e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LHPNHANK_01638 1.1e-48 yhbY J RNA-binding protein
LHPNHANK_01639 6e-213 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
LHPNHANK_01640 1.4e-98 yqeG S hydrolase of the HAD superfamily
LHPNHANK_01641 2.6e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LHPNHANK_01642 1.6e-64
LHPNHANK_01643 1e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LHPNHANK_01644 2.2e-271 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LHPNHANK_01645 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LHPNHANK_01646 1.1e-56 tagE 2.4.1.52 GT4 M transferase activity, transferring glycosyl groups
LHPNHANK_01647 1.5e-293 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LHPNHANK_01648 1e-90 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LHPNHANK_01649 6.7e-148 hlpA M Belongs to the NlpA lipoprotein family
LHPNHANK_01650 1.7e-99 pncA Q isochorismatase
LHPNHANK_01651 2.4e-139 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LHPNHANK_01652 7.6e-238 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
LHPNHANK_01653 9e-75 XK27_03180 T universal stress protein
LHPNHANK_01655 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LHPNHANK_01656 1.8e-08 MU outer membrane autotransporter barrel domain protein
LHPNHANK_01657 3.8e-238 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
LHPNHANK_01658 2.1e-143 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
LHPNHANK_01659 0.0 yjcE P NhaP-type Na H and K H antiporters
LHPNHANK_01661 1.7e-96 ytqB J (SAM)-dependent
LHPNHANK_01662 5.4e-183 yhcC S radical SAM protein
LHPNHANK_01663 4.2e-187 ylbL T Belongs to the peptidase S16 family
LHPNHANK_01664 5e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LHPNHANK_01665 5.5e-104 rsmD 2.1.1.171 L Methyltransferase
LHPNHANK_01666 2.1e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LHPNHANK_01667 5e-10 S Protein of unknown function (DUF4059)
LHPNHANK_01668 5.5e-130 tcyN 3.6.3.21 E abc transporter atp-binding protein
LHPNHANK_01669 5.2e-162 yxeN P ABC transporter (Permease
LHPNHANK_01670 4.8e-151 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
LHPNHANK_01671 2.8e-35
LHPNHANK_01672 9.5e-203 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LHPNHANK_01673 0.0 pflB 2.3.1.54 C formate acetyltransferase'
LHPNHANK_01675 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
LHPNHANK_01676 4.7e-148 cah 4.2.1.1 P carbonic anhydrase
LHPNHANK_01677 4.8e-76 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LHPNHANK_01679 9.7e-172 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
LHPNHANK_01680 6e-140 cppA E CppA N-terminal
LHPNHANK_01681 1.5e-97 V CAAX protease self-immunity
LHPNHANK_01682 2.7e-193 L PFAM Integrase, catalytic core
LHPNHANK_01683 1.2e-163 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
LHPNHANK_01684 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
LHPNHANK_01685 2.7e-193 L PFAM Integrase, catalytic core
LHPNHANK_01686 6.7e-07
LHPNHANK_01689 2e-43 spiA K sequence-specific DNA binding
LHPNHANK_01690 4.6e-193 L PFAM Integrase, catalytic core
LHPNHANK_01693 4.6e-203 L Transposase IS116 IS110 IS902
LHPNHANK_01694 3e-127 L overlaps another CDS with the same product name
LHPNHANK_01695 6.7e-76 L Transposase
LHPNHANK_01696 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
LHPNHANK_01697 2.4e-30 mesE M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LHPNHANK_01698 2.5e-123 L Molecular Function DNA binding, Biological Process DNA recombination
LHPNHANK_01699 5.3e-30 L transposase activity
LHPNHANK_01700 4e-154 blpT
LHPNHANK_01702 8e-08 S Class II bacteriocin
LHPNHANK_01703 3.3e-135 agrA KT phosphorelay signal transduction system
LHPNHANK_01711 0.0 mdlB V abc transporter atp-binding protein
LHPNHANK_01712 0.0 mdlA V abc transporter atp-binding protein
LHPNHANK_01715 2.3e-66 XK27_09885 V Glycopeptide antibiotics resistance protein
LHPNHANK_01716 6.7e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
LHPNHANK_01717 5.6e-63 yutD J protein conserved in bacteria
LHPNHANK_01718 9.6e-269 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
LHPNHANK_01720 9.4e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LHPNHANK_01721 3.7e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LHPNHANK_01722 0.0 ftsI 3.4.16.4 M penicillin-binding protein
LHPNHANK_01723 2.4e-45 ftsL D cell division protein FtsL
LHPNHANK_01724 8.8e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LHPNHANK_01726 3.7e-25
LHPNHANK_01729 5e-69 yhaI J Protein of unknown function (DUF805)
LHPNHANK_01730 4.3e-65 yhaI S Protein of unknown function (DUF805)
LHPNHANK_01731 1.5e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LHPNHANK_01732 8.8e-142 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LHPNHANK_01733 2.1e-272 XK27_00765
LHPNHANK_01734 4.4e-132 ecsA_2 V abc transporter atp-binding protein
LHPNHANK_01735 3.1e-125 S Protein of unknown function (DUF554)
LHPNHANK_01736 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
LHPNHANK_01737 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
LHPNHANK_01738 3.9e-246 2.7.13.3 T protein histidine kinase activity
LHPNHANK_01739 8.2e-238 dcuS 2.7.13.3 T protein histidine kinase activity
LHPNHANK_01740 8.9e-14
LHPNHANK_01743 5.8e-146 V Psort location CytoplasmicMembrane, score
LHPNHANK_01745 9.2e-300 O MreB/Mbl protein
LHPNHANK_01746 1.3e-117 liaI S membrane
LHPNHANK_01747 6.8e-75 XK27_02470 K LytTr DNA-binding domain protein
LHPNHANK_01748 0.0 KT response to antibiotic
LHPNHANK_01749 2.5e-124 yebC M Membrane
LHPNHANK_01750 1.6e-260 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
LHPNHANK_01751 2.9e-179 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
LHPNHANK_01753 2.9e-31 yozG K Transcriptional regulator
LHPNHANK_01757 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LHPNHANK_01758 4.1e-182 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LHPNHANK_01759 4.9e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LHPNHANK_01760 2.3e-206 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LHPNHANK_01761 3.3e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LHPNHANK_01762 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LHPNHANK_01764 5.6e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
LHPNHANK_01765 1.2e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
LHPNHANK_01766 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
LHPNHANK_01767 8.6e-289 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
LHPNHANK_01768 2.4e-178 scrR K Transcriptional regulator
LHPNHANK_01769 8.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LHPNHANK_01770 1.7e-61 yqhY S protein conserved in bacteria
LHPNHANK_01771 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LHPNHANK_01772 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
LHPNHANK_01773 4.1e-187 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
LHPNHANK_01775 3e-145 V 'abc transporter, ATP-binding protein
LHPNHANK_01776 9.5e-33 blpT
LHPNHANK_01780 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LHPNHANK_01781 1e-168 corA P COG0598 Mg2 and Co2 transporters
LHPNHANK_01782 2.6e-123 XK27_01040 S Protein of unknown function (DUF1129)
LHPNHANK_01784 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LHPNHANK_01785 2.5e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LHPNHANK_01786 6.6e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
LHPNHANK_01787 1.5e-42 XK27_05745
LHPNHANK_01788 6.1e-229 mutY L A G-specific adenine glycosylase
LHPNHANK_01789 7.6e-10
LHPNHANK_01790 1.3e-37
LHPNHANK_01791 4.6e-193 L PFAM Integrase, catalytic core
LHPNHANK_01792 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LHPNHANK_01793 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LHPNHANK_01794 6.1e-94 cvpA S toxin biosynthetic process
LHPNHANK_01795 9.3e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LHPNHANK_01796 5.9e-155 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LHPNHANK_01797 1.1e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
LHPNHANK_01798 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LHPNHANK_01799 3.7e-46 azlD S branched-chain amino acid
LHPNHANK_01800 3e-114 azlC E AzlC protein
LHPNHANK_01801 3.3e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LHPNHANK_01802 2e-71 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
LHPNHANK_01803 1.6e-115 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
LHPNHANK_01804 1.5e-33 ykzG S Belongs to the UPF0356 family
LHPNHANK_01805 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LHPNHANK_01806 1.4e-113 pscB M CHAP domain protein
LHPNHANK_01807 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
LHPNHANK_01808 2.5e-62 glnR K Transcriptional regulator
LHPNHANK_01809 3e-87 S Fusaric acid resistance protein-like
LHPNHANK_01810 5.8e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
LHPNHANK_01811 2.1e-123
LHPNHANK_01812 6.2e-185 gap 1.2.1.12 C Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LHPNHANK_01813 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LHPNHANK_01814 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LHPNHANK_01815 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LHPNHANK_01816 4e-142 purR 2.4.2.7 F operon repressor
LHPNHANK_01817 1.2e-177 cbf S 3'-5' exoribonuclease yhaM
LHPNHANK_01818 1.4e-170 rmuC S RmuC domain protein
LHPNHANK_01819 1.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
LHPNHANK_01820 7.8e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
LHPNHANK_01821 4e-164 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LHPNHANK_01823 3.1e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LHPNHANK_01824 2.9e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LHPNHANK_01825 6.6e-145 tatD L Hydrolase, tatd
LHPNHANK_01826 2.5e-74 yccU S CoA-binding protein
LHPNHANK_01827 6.3e-51 trxA O Belongs to the thioredoxin family
LHPNHANK_01828 6e-143 S Macro domain protein
LHPNHANK_01829 1.6e-272 L Transposase
LHPNHANK_01830 7.4e-60 L thioesterase
LHPNHANK_01831 2.6e-55 bta 1.8.1.8 CO cell redox homeostasis
LHPNHANK_01834 2.8e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LHPNHANK_01835 3.4e-14 rpmH J Ribosomal protein L34
LHPNHANK_01836 1.5e-103 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
LHPNHANK_01837 1.5e-106 K Transcriptional regulator
LHPNHANK_01838 8.8e-150 jag S RNA-binding protein
LHPNHANK_01839 9.7e-147 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LHPNHANK_01840 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LHPNHANK_01841 1.6e-263 argH 4.3.2.1 E Argininosuccinate lyase
LHPNHANK_01842 1.4e-228 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
LHPNHANK_01843 9.6e-152 L PFAM Integrase, catalytic core
LHPNHANK_01844 2.8e-134 fasA KT Response regulator of the LytR AlgR family
LHPNHANK_01845 4.7e-241 fasC 2.7.13.3 T protein histidine kinase activity
LHPNHANK_01846 9.3e-210 hpk9 2.7.13.3 T protein histidine kinase activity
LHPNHANK_01847 2.5e-153 hpk9 2.7.13.3 T protein histidine kinase activity
LHPNHANK_01848 1.7e-230 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
LHPNHANK_01849 1.8e-273 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LHPNHANK_01850 0.0 amiA E ABC transporter, substrate-binding protein, family 5
LHPNHANK_01851 1.4e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LHPNHANK_01852 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LHPNHANK_01853 1.2e-50 S Protein of unknown function (DUF3397)
LHPNHANK_01854 1.2e-85 cah 4.2.1.1 P Reversible hydration of carbon dioxide
LHPNHANK_01855 1.6e-126 WQ51_05710 S Mitochondrial biogenesis AIM24
LHPNHANK_01856 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LHPNHANK_01857 1.9e-73 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
LHPNHANK_01858 1.2e-79 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
LHPNHANK_01859 6.3e-108 XK27_09620 S FMN reductase (NADPH) activity
LHPNHANK_01860 7.9e-230 XK27_09615 C reductase
LHPNHANK_01861 1.1e-57 fnt P Formate nitrite transporter
LHPNHANK_01862 4.4e-55 fnt P Formate nitrite transporter
LHPNHANK_01863 3.9e-96 XK27_08585 S Psort location CytoplasmicMembrane, score
LHPNHANK_01864 3.7e-185 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
LHPNHANK_01865 6.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
LHPNHANK_01866 5.4e-116 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
LHPNHANK_01867 1.3e-93 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LHPNHANK_01868 2.3e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LHPNHANK_01869 5.3e-58 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LHPNHANK_01870 1.8e-141 S HAD hydrolase, family IA, variant
LHPNHANK_01871 1.2e-160 rrmA 2.1.1.187 Q methyltransferase
LHPNHANK_01875 3.9e-90 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LHPNHANK_01876 3.3e-65 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LHPNHANK_01877 8.3e-37 yeeD O sulfur carrier activity
LHPNHANK_01878 5.8e-186 yeeE S Sulphur transport
LHPNHANK_01879 1.1e-112 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LHPNHANK_01880 1e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
LHPNHANK_01881 3.5e-08 XK27_10305 S Domain of unknown function (DUF4651)
LHPNHANK_01882 7.7e-202 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
LHPNHANK_01883 1.4e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LHPNHANK_01884 3e-111 S CAAX amino terminal protease family protein
LHPNHANK_01886 2.5e-110 V CAAX protease self-immunity
LHPNHANK_01887 8.8e-27 lanR K sequence-specific DNA binding
LHPNHANK_01888 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LHPNHANK_01889 7.7e-177 ytxK 2.1.1.72 L DNA methylase
LHPNHANK_01890 5.8e-12 comGF U Putative Competence protein ComGF
LHPNHANK_01891 5.3e-72 comGF U Competence protein ComGF
LHPNHANK_01892 3.1e-15 NU Type II secretory pathway pseudopilin
LHPNHANK_01893 1.9e-69 cglD NU Competence protein
LHPNHANK_01894 2.2e-43 comGC U Required for transformation and DNA binding
LHPNHANK_01895 1.5e-141 cglB U protein transport across the cell outer membrane
LHPNHANK_01896 2.4e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LHPNHANK_01897 1e-68 S cog cog4699
LHPNHANK_01898 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LHPNHANK_01899 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LHPNHANK_01900 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LHPNHANK_01901 1.9e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LHPNHANK_01902 4.6e-193 L PFAM Integrase, catalytic core
LHPNHANK_01903 3e-195 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LHPNHANK_01904 2.2e-76 ilvN 2.2.1.6 E Acetolactate synthase
LHPNHANK_01905 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
LHPNHANK_01906 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
LHPNHANK_01907 3.8e-304 yloV S kinase related to dihydroxyacetone kinase
LHPNHANK_01908 1.4e-57 asp S cog cog1302
LHPNHANK_01909 7.1e-226 norN V Mate efflux family protein
LHPNHANK_01910 1.3e-276 thrC 4.2.3.1 E Threonine synthase
LHPNHANK_01913 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
LHPNHANK_01914 0.0 pepO 3.4.24.71 O Peptidase family M13
LHPNHANK_01915 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
LHPNHANK_01916 0.0 treB 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
LHPNHANK_01917 6e-126 treR K trehalose operon
LHPNHANK_01918 2.2e-94 ywlG S Belongs to the UPF0340 family
LHPNHANK_01921 8.2e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
LHPNHANK_01922 4.6e-193 L PFAM Integrase, catalytic core
LHPNHANK_01924 2.7e-241 6.3.2.2 H gamma-glutamylcysteine synthetase
LHPNHANK_01925 4.4e-62 rplQ J ribosomal protein l17
LHPNHANK_01926 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LHPNHANK_01927 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LHPNHANK_01928 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LHPNHANK_01929 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
LHPNHANK_01930 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LHPNHANK_01931 7.3e-118 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LHPNHANK_01932 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LHPNHANK_01933 5.7e-58 rplO J binds to the 23S rRNA
LHPNHANK_01934 1.9e-23 rpmD J ribosomal protein l30
LHPNHANK_01935 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LHPNHANK_01936 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LHPNHANK_01937 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LHPNHANK_01938 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LHPNHANK_01939 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LHPNHANK_01940 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LHPNHANK_01941 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LHPNHANK_01942 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LHPNHANK_01943 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LHPNHANK_01944 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
LHPNHANK_01945 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LHPNHANK_01946 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LHPNHANK_01947 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LHPNHANK_01948 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LHPNHANK_01949 6.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LHPNHANK_01950 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LHPNHANK_01951 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
LHPNHANK_01952 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LHPNHANK_01953 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
LHPNHANK_01954 3e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LHPNHANK_01955 2.3e-192 L PFAM Integrase, catalytic core
LHPNHANK_01956 0.0 XK27_09800 I Acyltransferase
LHPNHANK_01957 9.7e-36 XK27_09805 S MORN repeat protein
LHPNHANK_01958 1.7e-78 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LHPNHANK_01959 1e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LHPNHANK_01960 5.7e-94 adk 2.7.4.3 F topology modulation protein
LHPNHANK_01961 9.8e-160 T Calcineurin-like phosphoesterase superfamily domain
LHPNHANK_01962 4.3e-170 yeiH S membrane
LHPNHANK_01963 2.3e-87 K sequence-specific DNA binding
LHPNHANK_01964 8.8e-160 L Replication initiation factor
LHPNHANK_01965 1.9e-18 S Domain of unknown function (DUF3173)
LHPNHANK_01966 1.3e-215 int L Belongs to the 'phage' integrase family
LHPNHANK_01968 1.8e-234 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
LHPNHANK_01969 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
LHPNHANK_01970 6.3e-44 yrzL S Belongs to the UPF0297 family
LHPNHANK_01971 1.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LHPNHANK_01972 3.2e-44 yrzB S Belongs to the UPF0473 family
LHPNHANK_01973 3.1e-290 ccs S the current gene model (or a revised gene model) may contain a frame shift
LHPNHANK_01974 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
LHPNHANK_01975 7.5e-14
LHPNHANK_01976 5.4e-89 XK27_10930 K acetyltransferase
LHPNHANK_01977 2.4e-115 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LHPNHANK_01978 7.5e-121 yaaA S Belongs to the UPF0246 family
LHPNHANK_01979 3.2e-167 XK27_01785 S cog cog1284
LHPNHANK_01980 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
LHPNHANK_01982 7e-242 hisS 6.1.1.21 J histidyl-tRNA synthetase
LHPNHANK_01983 1e-210 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
LHPNHANK_01984 1.5e-219 metE 2.1.1.14 E Methionine synthase
LHPNHANK_01985 1.5e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
LHPNHANK_01986 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
LHPNHANK_01991 7e-115 nudL L hydrolase
LHPNHANK_01992 6.3e-54 K transcriptional regulator, PadR family
LHPNHANK_01993 8.6e-62 XK27_06920 S Protein of unknown function (DUF1700)
LHPNHANK_01994 1.4e-108 S Putative adhesin
LHPNHANK_01995 3.6e-159 XK27_06930 V domain protein
LHPNHANK_01996 9.9e-97 XK27_06935 K transcriptional regulator
LHPNHANK_01997 4.1e-54 ypaA M Membrane
LHPNHANK_01998 1.9e-10
LHPNHANK_01999 5.5e-25
LHPNHANK_02000 1.1e-23 arpU S Transcriptional regulator, ArpU family
LHPNHANK_02002 1.2e-243 S DNA primase
LHPNHANK_02003 1.4e-140 KL Phage plasmid primase P4 family
LHPNHANK_02004 9e-22
LHPNHANK_02005 1.3e-14
LHPNHANK_02007 9.6e-11
LHPNHANK_02010 4.3e-14 K Cro/C1-type HTH DNA-binding domain
LHPNHANK_02011 9.4e-185 sip L Belongs to the 'phage' integrase family
LHPNHANK_02012 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LHPNHANK_02013 2.4e-47 veg S Biofilm formation stimulator VEG
LHPNHANK_02014 1e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
LHPNHANK_02015 2.2e-73 rplI J binds to the 23S rRNA
LHPNHANK_02016 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
LHPNHANK_02017 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LHPNHANK_02018 2.4e-99 yvbG U UPF0056 membrane protein
LHPNHANK_02019 5.1e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LHPNHANK_02020 0.0 S Bacterial membrane protein, YfhO
LHPNHANK_02021 5.8e-73 isaA GH23 M Immunodominant staphylococcal antigen A
LHPNHANK_02022 3.5e-60 lytE M LysM domain protein
LHPNHANK_02023 2.8e-132 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LHPNHANK_02024 1.6e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LHPNHANK_02025 2.4e-150 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LHPNHANK_02026 4.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LHPNHANK_02027 2.1e-133 S sequence-specific DNA binding
LHPNHANK_02028 6.4e-235 ymfH S Peptidase M16
LHPNHANK_02029 3.5e-230 ymfF S Peptidase M16
LHPNHANK_02030 9.8e-59 yaaA S S4 domain protein YaaA
LHPNHANK_02031 3.8e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LHPNHANK_02032 5.6e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
LHPNHANK_02033 2.4e-192 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
LHPNHANK_02034 2.2e-154 yvjA S membrane
LHPNHANK_02035 5.1e-306 ybiT S abc transporter atp-binding protein
LHPNHANK_02036 0.0 XK27_10405 S Bacterial membrane protein YfhO
LHPNHANK_02040 6.2e-120 yoaK S Protein of unknown function (DUF1275)
LHPNHANK_02041 8e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LHPNHANK_02042 9.2e-207 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
LHPNHANK_02043 2.6e-135 parB K Belongs to the ParB family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)