ORF_ID e_value Gene_name EC_number CAZy COGs Description
MDNLPGOO_00001 7.6e-244 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MDNLPGOO_00002 1.2e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MDNLPGOO_00003 3.4e-208 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MDNLPGOO_00004 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDNLPGOO_00005 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDNLPGOO_00006 9.4e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
MDNLPGOO_00007 9.6e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MDNLPGOO_00008 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MDNLPGOO_00009 2.9e-157 corA P CorA-like Mg2+ transporter protein
MDNLPGOO_00010 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MDNLPGOO_00011 4.8e-76 rplI J Binds to the 23S rRNA
MDNLPGOO_00012 1.6e-244 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MDNLPGOO_00013 3.8e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
MDNLPGOO_00014 2.2e-215 I Protein of unknown function (DUF2974)
MDNLPGOO_00015 0.0
MDNLPGOO_00017 5.6e-46 steT E amino acid
MDNLPGOO_00018 1.2e-119 steT E amino acid
MDNLPGOO_00020 4.8e-111 L Resolvase, N terminal domain
MDNLPGOO_00021 1.2e-252 L Probable transposase
MDNLPGOO_00022 4.6e-199 L COG2826 Transposase and inactivated derivatives, IS30 family
MDNLPGOO_00023 0.0 3.2.1.18 GH33 M Rib/alpha-like repeat
MDNLPGOO_00024 7.2e-09
MDNLPGOO_00025 4.6e-12 L PFAM IS66 Orf2 family protein
MDNLPGOO_00026 1.7e-09 L Belongs to the 'phage' integrase family
MDNLPGOO_00027 3.7e-82 S Sterol carrier protein domain
MDNLPGOO_00028 6.7e-24 arbZ I Acyltransferase
MDNLPGOO_00029 1.3e-111 L Resolvase, N terminal domain
MDNLPGOO_00030 1.1e-253 L Probable transposase
MDNLPGOO_00031 9.3e-59 arbZ I Acyltransferase
MDNLPGOO_00032 9.7e-115 ywnB S NAD(P)H-binding
MDNLPGOO_00033 6.2e-64 S Protein of unknown function (DUF975)
MDNLPGOO_00034 0.0 tetP J Elongation factor G, domain IV
MDNLPGOO_00035 1.6e-62 ywnB S NAD(P)H-binding
MDNLPGOO_00036 5.3e-119 S Protein of unknown function (DUF975)
MDNLPGOO_00037 1.3e-136 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MDNLPGOO_00038 1.3e-151 yitS S EDD domain protein, DegV family
MDNLPGOO_00039 3.5e-17
MDNLPGOO_00040 0.0 tetP J elongation factor G
MDNLPGOO_00041 1.9e-164 L Transposase
MDNLPGOO_00042 2e-43 L Transposase
MDNLPGOO_00044 7.2e-74 K Copper transport repressor CopY TcrY
MDNLPGOO_00045 0.0 copB 3.6.3.4 P P-type ATPase
MDNLPGOO_00047 1.5e-244 L Transposase
MDNLPGOO_00048 2.1e-225 clcA P chloride
MDNLPGOO_00050 3.9e-15
MDNLPGOO_00053 5.3e-100 ropB K Transcriptional regulator
MDNLPGOO_00054 1.6e-182 XK27_02480 EGP Major facilitator Superfamily
MDNLPGOO_00055 3.5e-09 S YcaO cyclodehydratase, ATP-ad Mg2+-binding
MDNLPGOO_00056 1.4e-17
MDNLPGOO_00058 4.2e-40 S Transglycosylase associated protein
MDNLPGOO_00059 1.2e-157 xth 3.1.11.2 L exodeoxyribonuclease III
MDNLPGOO_00060 0.0 L Helicase C-terminal domain protein
MDNLPGOO_00061 7.7e-139 S Alpha beta hydrolase
MDNLPGOO_00062 8.3e-27
MDNLPGOO_00063 1.9e-168 K AI-2E family transporter
MDNLPGOO_00067 8e-108 msbA2 3.6.3.44 V ABC transporter
MDNLPGOO_00068 3.6e-112 KLT Protein kinase domain
MDNLPGOO_00071 2.3e-46 2.7.13.3 T GHKL domain
MDNLPGOO_00072 3.8e-50 K LytTr DNA-binding domain
MDNLPGOO_00073 5.1e-243 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
MDNLPGOO_00074 3.2e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MDNLPGOO_00075 9.3e-101 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
MDNLPGOO_00076 1.5e-191 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDNLPGOO_00077 0.0 S domain, Protein
MDNLPGOO_00078 1.1e-259 E amino acid
MDNLPGOO_00079 9.8e-169 K LysR substrate binding domain
MDNLPGOO_00080 0.0 1.3.5.4 C FAD binding domain
MDNLPGOO_00081 1e-238 brnQ U Component of the transport system for branched-chain amino acids
MDNLPGOO_00082 3.3e-135 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MDNLPGOO_00083 7.9e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
MDNLPGOO_00084 2.7e-182 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
MDNLPGOO_00085 4.3e-24 yhjX_2 P Major Facilitator Superfamily
MDNLPGOO_00086 2e-112 yhjX_2 P Major Facilitator Superfamily
MDNLPGOO_00087 1.3e-24 yhjX_2 P Major Facilitator Superfamily
MDNLPGOO_00088 3.2e-131 arbZ I Phosphate acyltransferases
MDNLPGOO_00091 2.6e-129 K response regulator
MDNLPGOO_00092 0.0 vicK 2.7.13.3 T Histidine kinase
MDNLPGOO_00093 1.5e-242 yycH S YycH protein
MDNLPGOO_00094 6.3e-143 yycI S YycH protein
MDNLPGOO_00095 3.1e-147 vicX 3.1.26.11 S domain protein
MDNLPGOO_00096 2.1e-174 htrA 3.4.21.107 O serine protease
MDNLPGOO_00097 1.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MDNLPGOO_00098 1e-108 P Cobalt transport protein
MDNLPGOO_00099 5.5e-245 cbiO1 S ABC transporter, ATP-binding protein
MDNLPGOO_00100 2.3e-96 S ABC-type cobalt transport system, permease component
MDNLPGOO_00101 1.3e-160 K helix_turn_helix, arabinose operon control protein
MDNLPGOO_00102 6.5e-162 htpX O Belongs to the peptidase M48B family
MDNLPGOO_00103 1.3e-88 lemA S LemA family
MDNLPGOO_00104 1.5e-179 ybiR P Citrate transporter
MDNLPGOO_00105 1e-64 S Iron-sulphur cluster biosynthesis
MDNLPGOO_00106 1.7e-16
MDNLPGOO_00107 1e-119
MDNLPGOO_00109 1.4e-218 ydaM M Glycosyl transferase
MDNLPGOO_00110 7.2e-153 G Glycosyl hydrolases family 8
MDNLPGOO_00111 4.2e-30 G Glycosyl hydrolases family 8
MDNLPGOO_00112 4.5e-120 yfbR S HD containing hydrolase-like enzyme
MDNLPGOO_00113 1.4e-161 L HNH nucleases
MDNLPGOO_00114 1.4e-136 glnQ E ABC transporter, ATP-binding protein
MDNLPGOO_00115 2.6e-294 glnP P ABC transporter permease
MDNLPGOO_00116 5.2e-113 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
MDNLPGOO_00117 1.7e-60 yeaO S Protein of unknown function, DUF488
MDNLPGOO_00118 1.5e-122 terC P Integral membrane protein TerC family
MDNLPGOO_00119 1.3e-85 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
MDNLPGOO_00120 1.3e-128 cobB K SIR2 family
MDNLPGOO_00121 2.6e-80
MDNLPGOO_00122 2.9e-284 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MDNLPGOO_00123 8.1e-123 yugP S Putative neutral zinc metallopeptidase
MDNLPGOO_00124 8.6e-173 S Alpha/beta hydrolase of unknown function (DUF915)
MDNLPGOO_00125 1.9e-138 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MDNLPGOO_00127 9e-157 ypuA S Protein of unknown function (DUF1002)
MDNLPGOO_00128 9.7e-152 epsV 2.7.8.12 S glycosyl transferase family 2
MDNLPGOO_00129 4e-124 S Alpha/beta hydrolase family
MDNLPGOO_00130 7e-62
MDNLPGOO_00131 2.7e-180 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MDNLPGOO_00133 8.3e-104 S CAAX protease self-immunity
MDNLPGOO_00134 2.5e-237 cycA E Amino acid permease
MDNLPGOO_00135 1.2e-112 luxT K Bacterial regulatory proteins, tetR family
MDNLPGOO_00136 1e-124
MDNLPGOO_00137 1.5e-262 S Cysteine-rich secretory protein family
MDNLPGOO_00138 6.2e-207 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MDNLPGOO_00139 3.8e-72
MDNLPGOO_00140 1.5e-270 yjcE P Sodium proton antiporter
MDNLPGOO_00141 7.6e-168 yibE S overlaps another CDS with the same product name
MDNLPGOO_00142 8.4e-118 yibF S overlaps another CDS with the same product name
MDNLPGOO_00143 6.7e-153 I alpha/beta hydrolase fold
MDNLPGOO_00144 0.0 G Belongs to the glycosyl hydrolase 31 family
MDNLPGOO_00145 2.1e-126 XK27_08435 K UTRA
MDNLPGOO_00146 2e-211 agaS G SIS domain
MDNLPGOO_00147 2e-227 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MDNLPGOO_00148 5.7e-83 2.7.1.191 G PTS system sorbose subfamily IIB component
MDNLPGOO_00149 3.1e-135 XK27_08455 G PTS system sorbose-specific iic component
MDNLPGOO_00150 7.1e-147 manZ_1 G PTS system mannose/fructose/sorbose family IID component
MDNLPGOO_00151 3.9e-66 2.7.1.191 G PTS system fructose IIA component
MDNLPGOO_00153 8.6e-162 S zinc-ribbon domain
MDNLPGOO_00154 2.6e-40 S MORN repeat protein
MDNLPGOO_00155 3.5e-271 XK27_09800 I Acyltransferase family
MDNLPGOO_00158 7.3e-61 L COG3547 Transposase and inactivated derivatives
MDNLPGOO_00159 4.8e-87 ntd 2.4.2.6 F Nucleoside
MDNLPGOO_00160 1e-99 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MDNLPGOO_00161 1.5e-127 XK27_08440 K UTRA domain
MDNLPGOO_00162 7.5e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
MDNLPGOO_00163 1e-87 uspA T universal stress protein
MDNLPGOO_00165 8.3e-168 phnD P Phosphonate ABC transporter
MDNLPGOO_00166 2.4e-139 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MDNLPGOO_00167 1.3e-129 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
MDNLPGOO_00168 9.2e-147 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
MDNLPGOO_00169 7.3e-83
MDNLPGOO_00170 1.4e-272 S Calcineurin-like phosphoesterase
MDNLPGOO_00171 0.0 asnB 6.3.5.4 E Asparagine synthase
MDNLPGOO_00172 6.1e-265 yxbA 6.3.1.12 S ATP-grasp enzyme
MDNLPGOO_00173 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
MDNLPGOO_00174 3.1e-130 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MDNLPGOO_00175 1.6e-103 S Iron-sulfur cluster assembly protein
MDNLPGOO_00176 3.5e-227 XK27_04775 S PAS domain
MDNLPGOO_00177 6.3e-224 yttB EGP Major facilitator Superfamily
MDNLPGOO_00178 4e-184 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
MDNLPGOO_00179 7.7e-167 D nuclear chromosome segregation
MDNLPGOO_00180 7.6e-135 rpl K Helix-turn-helix domain, rpiR family
MDNLPGOO_00181 3.8e-165 pfkB 2.7.1.11, 2.7.1.56 H pfkB family carbohydrate kinase
MDNLPGOO_00182 9.8e-300 fruA 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MDNLPGOO_00183 2.8e-36 fruA 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MDNLPGOO_00184 0.0 pepO 3.4.24.71 O Peptidase family M13
MDNLPGOO_00185 0.0 S Bacterial membrane protein, YfhO
MDNLPGOO_00186 2.1e-227 L COG3547 Transposase and inactivated derivatives
MDNLPGOO_00187 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
MDNLPGOO_00188 0.0 kup P Transport of potassium into the cell
MDNLPGOO_00189 0.0 kup P Transport of potassium into the cell
MDNLPGOO_00190 1.8e-38 kup P Transport of potassium into the cell
MDNLPGOO_00191 0.0 L Transposase
MDNLPGOO_00192 5.6e-71
MDNLPGOO_00193 2.6e-109
MDNLPGOO_00194 2e-33 S Protein of unknown function (DUF2922)
MDNLPGOO_00195 7.8e-216 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MDNLPGOO_00196 2e-213 lysA2 M Glycosyl hydrolases family 25
MDNLPGOO_00197 9.9e-141 fruK 2.7.1.11, 2.7.1.56 G pfkB family carbohydrate kinase
MDNLPGOO_00198 0.0 yjbQ P TrkA C-terminal domain protein
MDNLPGOO_00199 2.5e-175 S Oxidoreductase family, NAD-binding Rossmann fold
MDNLPGOO_00200 8.3e-137
MDNLPGOO_00201 2.7e-141
MDNLPGOO_00202 2.3e-72 S PAS domain
MDNLPGOO_00203 1.1e-132 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MDNLPGOO_00205 1.7e-39
MDNLPGOO_00206 1.6e-14
MDNLPGOO_00207 4.6e-11
MDNLPGOO_00208 2.2e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MDNLPGOO_00209 3.4e-71 2.4.1.83 GT2 S GtrA-like protein
MDNLPGOO_00210 1.2e-177 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
MDNLPGOO_00211 2.3e-47 lmrB EGP Major facilitator Superfamily
MDNLPGOO_00212 1.8e-23 lmrB EGP Major facilitator Superfamily
MDNLPGOO_00213 2.2e-32 lmrB EGP Major facilitator Superfamily
MDNLPGOO_00214 1.3e-117
MDNLPGOO_00215 6.6e-151 glcU U sugar transport
MDNLPGOO_00216 1.6e-168 yqhA G Aldose 1-epimerase
MDNLPGOO_00217 1.5e-192 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MDNLPGOO_00218 6.2e-111 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MDNLPGOO_00219 0.0 XK27_08315 M Sulfatase
MDNLPGOO_00220 5.5e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MDNLPGOO_00222 1.2e-252 pepC 3.4.22.40 E aminopeptidase
MDNLPGOO_00223 4.5e-193 oppA E ABC transporter, substratebinding protein
MDNLPGOO_00224 1.3e-125 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDNLPGOO_00225 1.3e-150 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDNLPGOO_00226 9.6e-173 oppD P Belongs to the ABC transporter superfamily
MDNLPGOO_00227 2.9e-136 oppF P Belongs to the ABC transporter superfamily
MDNLPGOO_00228 1.5e-118 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
MDNLPGOO_00229 3.4e-252 pepC 3.4.22.40 E aminopeptidase
MDNLPGOO_00230 1.5e-32
MDNLPGOO_00231 4.1e-75 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MDNLPGOO_00232 2.6e-41 L Helix-turn-helix domain
MDNLPGOO_00233 3.1e-102 L PFAM Integrase catalytic region
MDNLPGOO_00234 3e-72 hsp O Belongs to the small heat shock protein (HSP20) family
MDNLPGOO_00235 2.2e-292 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MDNLPGOO_00236 5.6e-78
MDNLPGOO_00237 1.8e-240 celD 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDNLPGOO_00238 2.4e-127 yydK K UTRA
MDNLPGOO_00239 7.3e-68 S Domain of unknown function (DUF3284)
MDNLPGOO_00240 7.3e-299 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MDNLPGOO_00241 2.1e-134 gmuR K UTRA
MDNLPGOO_00242 1.5e-50 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
MDNLPGOO_00243 1.8e-40
MDNLPGOO_00244 2.6e-52 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
MDNLPGOO_00245 6e-266 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDNLPGOO_00246 8e-276 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MDNLPGOO_00247 4.8e-154 ypbG 2.7.1.2 GK ROK family
MDNLPGOO_00248 1.5e-115
MDNLPGOO_00250 8.6e-113 E Belongs to the SOS response-associated peptidase family
MDNLPGOO_00251 2e-194 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
MDNLPGOO_00252 4.3e-91 comEB 3.5.4.12 F MafB19-like deaminase
MDNLPGOO_00253 3.8e-97 S TPM domain
MDNLPGOO_00254 2.7e-180 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
MDNLPGOO_00255 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MDNLPGOO_00256 5.7e-146 tatD L hydrolase, TatD family
MDNLPGOO_00257 1.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MDNLPGOO_00258 4.4e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MDNLPGOO_00259 4.8e-35 veg S Biofilm formation stimulator VEG
MDNLPGOO_00260 2.9e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
MDNLPGOO_00261 7.7e-218 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MDNLPGOO_00262 1.1e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MDNLPGOO_00263 6e-174 yvdE K helix_turn _helix lactose operon repressor
MDNLPGOO_00264 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
MDNLPGOO_00265 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
MDNLPGOO_00266 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
MDNLPGOO_00267 9e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
MDNLPGOO_00268 8e-210 msmX P Belongs to the ABC transporter superfamily
MDNLPGOO_00269 5.3e-215 malE G Bacterial extracellular solute-binding protein
MDNLPGOO_00270 3.6e-252 malF P Binding-protein-dependent transport system inner membrane component
MDNLPGOO_00271 4.1e-153 malG P ABC transporter permease
MDNLPGOO_00272 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
MDNLPGOO_00273 5.1e-267 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
MDNLPGOO_00274 8.1e-73 S Domain of unknown function (DUF1934)
MDNLPGOO_00275 5.5e-63 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MDNLPGOO_00276 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MDNLPGOO_00277 8.5e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MDNLPGOO_00278 1.3e-235 pbuX F xanthine permease
MDNLPGOO_00279 7.6e-103 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MDNLPGOO_00280 5.8e-104 K DNA-binding helix-turn-helix protein
MDNLPGOO_00281 5.1e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MDNLPGOO_00283 2.6e-77 2.1.1.72 V Type II restriction enzyme, methylase subunits
MDNLPGOO_00284 6.9e-203 L COG2826 Transposase and inactivated derivatives, IS30 family
MDNLPGOO_00285 0.0 2.1.1.72 V Type II restriction enzyme, methylase subunits
MDNLPGOO_00288 7.6e-15
MDNLPGOO_00289 5e-132 D ftsk spoiiie
MDNLPGOO_00290 2.5e-105
MDNLPGOO_00291 3.8e-15 S Domain of unknown function (DUF3173)
MDNLPGOO_00292 5.1e-173 L Belongs to the 'phage' integrase family
MDNLPGOO_00293 5.3e-56 hxlR K Transcriptional regulator, HxlR family
MDNLPGOO_00294 1.3e-185 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
MDNLPGOO_00295 3.2e-12
MDNLPGOO_00296 7.3e-107 K transcriptional regulator
MDNLPGOO_00297 3.9e-95 yxkA S Phosphatidylethanolamine-binding protein
MDNLPGOO_00298 1.3e-110 L Transposase
MDNLPGOO_00299 6.2e-88
MDNLPGOO_00300 3.1e-35
MDNLPGOO_00302 1.5e-74
MDNLPGOO_00303 3.9e-32 hxlR K Transcriptional regulator, HxlR family
MDNLPGOO_00304 2.9e-81 XK27_02070 S Nitroreductase family
MDNLPGOO_00305 2.1e-140 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
MDNLPGOO_00306 5.9e-282 pipD E Dipeptidase
MDNLPGOO_00307 7.9e-154 msmR K AraC-like ligand binding domain
MDNLPGOO_00308 0.0 gph G Transporter
MDNLPGOO_00309 0.0 rafA 3.2.1.22 G alpha-galactosidase
MDNLPGOO_00310 2.4e-278 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
MDNLPGOO_00311 3.6e-227 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MDNLPGOO_00312 1.4e-176 ABC-SBP S ABC transporter
MDNLPGOO_00313 1.3e-138 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
MDNLPGOO_00314 6.5e-134 XK27_08845 S ABC transporter, ATP-binding protein
MDNLPGOO_00315 2.3e-295 ybeC E amino acid
MDNLPGOO_00316 1.4e-40 rpmE2 J Ribosomal protein L31
MDNLPGOO_00317 6.1e-260 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MDNLPGOO_00318 1e-265 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MDNLPGOO_00319 2.5e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MDNLPGOO_00320 1.3e-212 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MDNLPGOO_00321 3.5e-123 S (CBS) domain
MDNLPGOO_00322 4.7e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MDNLPGOO_00323 2.5e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MDNLPGOO_00324 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MDNLPGOO_00325 5.4e-34 yabO J S4 domain protein
MDNLPGOO_00326 4e-60 divIC D Septum formation initiator
MDNLPGOO_00327 2.7e-58 yabR J S1 RNA binding domain
MDNLPGOO_00328 1.1e-240 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MDNLPGOO_00329 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MDNLPGOO_00330 0.0 S membrane
MDNLPGOO_00331 0.0 S membrane
MDNLPGOO_00332 5.4e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MDNLPGOO_00333 5.8e-191 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MDNLPGOO_00334 9.9e-299 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MDNLPGOO_00336 1.4e-11 V Type II restriction enzyme, methylase subunits
MDNLPGOO_00338 1.2e-48 V Type II restriction enzyme, methylase subunits
MDNLPGOO_00339 2.1e-94 natA1 S ABC transporter
MDNLPGOO_00340 5.5e-61 S ABC-2 family transporter protein
MDNLPGOO_00341 5.2e-67 S ABC-2 family transporter protein
MDNLPGOO_00343 4e-82 S ATP diphosphatase activity
MDNLPGOO_00344 2.2e-165 L Transposase
MDNLPGOO_00345 3.2e-234 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MDNLPGOO_00346 1.6e-08
MDNLPGOO_00348 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MDNLPGOO_00349 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDNLPGOO_00350 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDNLPGOO_00351 2.3e-95 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
MDNLPGOO_00352 3.5e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MDNLPGOO_00353 1e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MDNLPGOO_00354 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MDNLPGOO_00355 5.8e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
MDNLPGOO_00356 1.7e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MDNLPGOO_00357 1e-105 rplD J Forms part of the polypeptide exit tunnel
MDNLPGOO_00358 6.3e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MDNLPGOO_00359 1.6e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MDNLPGOO_00360 1.9e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MDNLPGOO_00361 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MDNLPGOO_00362 1.6e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MDNLPGOO_00363 6.6e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MDNLPGOO_00364 2.2e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
MDNLPGOO_00365 7.7e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MDNLPGOO_00366 5.6e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MDNLPGOO_00367 1.1e-34 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MDNLPGOO_00368 7.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MDNLPGOO_00369 2.3e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MDNLPGOO_00370 2.1e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MDNLPGOO_00371 1.5e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MDNLPGOO_00372 1.5e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MDNLPGOO_00373 1.9e-76 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MDNLPGOO_00374 1.4e-23 rpmD J Ribosomal protein L30
MDNLPGOO_00375 1.3e-70 rplO J Binds to the 23S rRNA
MDNLPGOO_00376 4.5e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MDNLPGOO_00377 6.6e-119 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MDNLPGOO_00378 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MDNLPGOO_00379 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MDNLPGOO_00380 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MDNLPGOO_00381 2.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MDNLPGOO_00382 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDNLPGOO_00383 7.4e-62 rplQ J Ribosomal protein L17
MDNLPGOO_00384 4e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDNLPGOO_00385 5e-159 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDNLPGOO_00386 7.3e-206 L Putative transposase DNA-binding domain
MDNLPGOO_00387 2e-138 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDNLPGOO_00388 8.7e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MDNLPGOO_00389 1.1e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MDNLPGOO_00390 1.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
MDNLPGOO_00391 5.6e-150 1.6.5.2 GM NmrA-like family
MDNLPGOO_00392 1.6e-108 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
MDNLPGOO_00393 1.5e-129 pgm3 G Belongs to the phosphoglycerate mutase family
MDNLPGOO_00394 2.6e-52 K Transcriptional regulator, ArsR family
MDNLPGOO_00395 6.5e-154 czcD P cation diffusion facilitator family transporter
MDNLPGOO_00396 7.2e-37
MDNLPGOO_00397 9.9e-12
MDNLPGOO_00398 2.9e-122 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MDNLPGOO_00399 2.9e-184 S AAA domain
MDNLPGOO_00400 1.5e-233 L COG3547 Transposase and inactivated derivatives
MDNLPGOO_00401 5e-51 ltrA S Bacterial low temperature requirement A protein (LtrA)
MDNLPGOO_00402 3.1e-264 pepC 3.4.22.40 E Peptidase C1-like family
MDNLPGOO_00403 4.6e-199 L COG2826 Transposase and inactivated derivatives, IS30 family
MDNLPGOO_00404 9e-88 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MDNLPGOO_00405 1.4e-75 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MDNLPGOO_00406 3.3e-103 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
MDNLPGOO_00407 1.1e-253 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MDNLPGOO_00408 1.5e-288 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MDNLPGOO_00409 1e-270 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MDNLPGOO_00410 1.3e-78 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MDNLPGOO_00411 6e-140 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDNLPGOO_00412 4.6e-89 yvrI K sigma factor activity
MDNLPGOO_00413 1.7e-34
MDNLPGOO_00414 6.9e-203 L COG2826 Transposase and inactivated derivatives, IS30 family
MDNLPGOO_00415 2.6e-280 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
MDNLPGOO_00416 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MDNLPGOO_00417 2e-225 G Major Facilitator Superfamily
MDNLPGOO_00418 8.7e-190 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MDNLPGOO_00419 1.8e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MDNLPGOO_00420 3.4e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MDNLPGOO_00421 1.5e-100 nusG K Participates in transcription elongation, termination and antitermination
MDNLPGOO_00422 5.3e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MDNLPGOO_00423 3.6e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MDNLPGOO_00424 2.3e-207 L Putative transposase DNA-binding domain
MDNLPGOO_00425 2.3e-108 glnP P ABC transporter permease
MDNLPGOO_00426 7.4e-115 glnQ 3.6.3.21 E ABC transporter
MDNLPGOO_00427 1.9e-144 aatB ET ABC transporter substrate-binding protein
MDNLPGOO_00428 5.8e-95 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MDNLPGOO_00429 9.4e-51 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MDNLPGOO_00430 1.5e-129 kcsA P Ion transport protein
MDNLPGOO_00431 1.1e-145 L Bifunctional protein
MDNLPGOO_00432 1.1e-33 K Helix-turn-helix XRE-family like proteins
MDNLPGOO_00433 4e-20 sagB C nitroreductase
MDNLPGOO_00434 5.1e-32 sagC
MDNLPGOO_00435 3e-78 sagD S YcaO cyclodehydratase, ATP-ad Mg2+-binding
MDNLPGOO_00437 7.7e-73 V ABC transporter
MDNLPGOO_00438 1.9e-53 S domain protein
MDNLPGOO_00439 4.1e-28
MDNLPGOO_00440 6.1e-111 rsmC 2.1.1.172 J Methyltransferase
MDNLPGOO_00441 3.6e-22
MDNLPGOO_00442 2.1e-88
MDNLPGOO_00443 2.4e-30 S Protein conserved in bacteria
MDNLPGOO_00444 1.7e-84 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MDNLPGOO_00445 4.7e-292 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MDNLPGOO_00446 1.7e-51 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MDNLPGOO_00447 2.4e-107 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MDNLPGOO_00448 9e-26 S Protein of unknown function (DUF2508)
MDNLPGOO_00449 3.1e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MDNLPGOO_00450 5e-51 yaaQ S Cyclic-di-AMP receptor
MDNLPGOO_00451 1.4e-153 holB 2.7.7.7 L DNA polymerase III
MDNLPGOO_00452 4.4e-58 yabA L Involved in initiation control of chromosome replication
MDNLPGOO_00453 1.7e-154 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MDNLPGOO_00454 8.7e-136 fat 3.1.2.21 I Acyl-ACP thioesterase
MDNLPGOO_00455 6.2e-80 folT S ECF transporter, substrate-specific component
MDNLPGOO_00456 1.1e-130 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
MDNLPGOO_00457 7.1e-95 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
MDNLPGOO_00458 2.4e-195 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MDNLPGOO_00459 1.1e-155 D nuclear chromosome segregation
MDNLPGOO_00460 7.1e-49
MDNLPGOO_00461 5.7e-112
MDNLPGOO_00462 2.7e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MDNLPGOO_00463 1.6e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MDNLPGOO_00464 5.4e-242 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MDNLPGOO_00465 3.3e-135 L oxidized base lesion DNA N-glycosylase activity
MDNLPGOO_00466 5.7e-69 apfA 2.7.7.72, 3.6.1.61 F NUDIX domain
MDNLPGOO_00467 2.3e-42 K Helix-turn-helix XRE-family like proteins
MDNLPGOO_00468 4e-96 K Helix-turn-helix XRE-family like proteins
MDNLPGOO_00470 5e-81
MDNLPGOO_00471 8.2e-295 uup S ABC transporter, ATP-binding protein
MDNLPGOO_00472 8.7e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MDNLPGOO_00473 3.7e-102 yvdD 3.2.2.10 S Belongs to the LOG family
MDNLPGOO_00474 5.7e-77 XK27_02470 K LytTr DNA-binding domain
MDNLPGOO_00475 3.4e-119 liaI S membrane
MDNLPGOO_00477 8.8e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MDNLPGOO_00478 5.3e-295 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MDNLPGOO_00479 8.1e-58
MDNLPGOO_00480 6.9e-31
MDNLPGOO_00481 0.0 nisT V ABC transporter
MDNLPGOO_00482 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MDNLPGOO_00483 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MDNLPGOO_00484 9.3e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MDNLPGOO_00485 4.3e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MDNLPGOO_00486 1e-38 yajC U Preprotein translocase
MDNLPGOO_00487 3.9e-281 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MDNLPGOO_00488 4.2e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MDNLPGOO_00489 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
MDNLPGOO_00490 1.4e-224 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MDNLPGOO_00491 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MDNLPGOO_00492 2.6e-42 yrzL S Belongs to the UPF0297 family
MDNLPGOO_00493 1.5e-71 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MDNLPGOO_00494 4.2e-39 yrzB S Belongs to the UPF0473 family
MDNLPGOO_00495 1.9e-92 cvpA S Colicin V production protein
MDNLPGOO_00496 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MDNLPGOO_00497 1.1e-52 trxA O Belongs to the thioredoxin family
MDNLPGOO_00498 3.2e-68 yslB S Protein of unknown function (DUF2507)
MDNLPGOO_00499 1.2e-143 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MDNLPGOO_00500 1e-116 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MDNLPGOO_00501 1.2e-216 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MDNLPGOO_00502 2.3e-138 ykuT M mechanosensitive ion channel
MDNLPGOO_00503 1.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MDNLPGOO_00504 9.6e-50
MDNLPGOO_00505 8e-210 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MDNLPGOO_00506 2.2e-174 ccpA K catabolite control protein A
MDNLPGOO_00507 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M Penicillin binding protein transpeptidase domain
MDNLPGOO_00508 2.6e-274 pepV 3.5.1.18 E dipeptidase PepV
MDNLPGOO_00509 1.2e-266 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MDNLPGOO_00510 1.3e-54
MDNLPGOO_00511 1.6e-268 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
MDNLPGOO_00512 7.1e-95 yutD S Protein of unknown function (DUF1027)
MDNLPGOO_00513 2.6e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MDNLPGOO_00514 4e-102 S Protein of unknown function (DUF1461)
MDNLPGOO_00515 2.7e-117 dedA S SNARE-like domain protein
MDNLPGOO_00516 2.7e-177 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
MDNLPGOO_00517 5.5e-62 yugI 5.3.1.9 J general stress protein
MDNLPGOO_00518 9.1e-23 S ORF located using Blastx
MDNLPGOO_00519 2.5e-15 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
MDNLPGOO_00524 5.5e-212 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MDNLPGOO_00525 1e-257 qacA EGP Major facilitator Superfamily
MDNLPGOO_00526 2.6e-41 L Helix-turn-helix domain
MDNLPGOO_00527 3.1e-102 L PFAM Integrase catalytic region
MDNLPGOO_00528 1.7e-111 3.6.1.27 I Acid phosphatase homologues
MDNLPGOO_00529 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MDNLPGOO_00530 1.2e-297 ytgP S Polysaccharide biosynthesis protein
MDNLPGOO_00531 4.5e-146 MA20_36090 S Protein of unknown function (DUF2974)
MDNLPGOO_00532 2.8e-134
MDNLPGOO_00533 4e-145 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MDNLPGOO_00534 2e-166 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MDNLPGOO_00535 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MDNLPGOO_00536 5e-173 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
MDNLPGOO_00537 5.3e-42
MDNLPGOO_00538 1.3e-81 K Sigma-54 interaction domain
MDNLPGOO_00539 4.9e-49 K Sigma-54 interaction domain
MDNLPGOO_00541 4.7e-91 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MDNLPGOO_00542 3.1e-124 yfeJ 6.3.5.2 F Glutamine amidotransferase class-I
MDNLPGOO_00543 1.3e-76 ylbE GM NAD(P)H-binding
MDNLPGOO_00544 4.7e-249 L transposase, IS605 OrfB family
MDNLPGOO_00545 5.7e-85 tlpA2 L Transposase IS200 like
MDNLPGOO_00546 1.4e-80 yebR 1.8.4.14 T GAF domain-containing protein
MDNLPGOO_00547 5.5e-198 yfeO P Voltage gated chloride channel
MDNLPGOO_00548 3.1e-189 S Bacteriocin helveticin-J
MDNLPGOO_00549 1e-96 tag 3.2.2.20 L glycosylase
MDNLPGOO_00550 8.4e-160 mleP3 S Membrane transport protein
MDNLPGOO_00551 1.5e-136 S CAAX amino terminal protease
MDNLPGOO_00552 1.8e-141 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MDNLPGOO_00553 2.5e-251 emrY EGP Major facilitator Superfamily
MDNLPGOO_00554 7.4e-256 emrY EGP Major facilitator Superfamily
MDNLPGOO_00555 7.5e-217 L COG3547 Transposase and inactivated derivatives
MDNLPGOO_00556 2.7e-20 ybfG M peptidoglycan-binding domain-containing protein
MDNLPGOO_00557 1.3e-111 L Resolvase, N terminal domain
MDNLPGOO_00558 1.1e-253 L Probable transposase
MDNLPGOO_00559 5.4e-190 ybfG M peptidoglycan-binding domain-containing protein
MDNLPGOO_00561 1.8e-16
MDNLPGOO_00562 1.5e-85 2.3.1.128 K acetyltransferase
MDNLPGOO_00563 5.2e-22 S PFAM Archaeal ATPase
MDNLPGOO_00564 2.8e-54 S PFAM Archaeal ATPase
MDNLPGOO_00565 4.9e-22 S PFAM Archaeal ATPase
MDNLPGOO_00566 6.7e-126 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
MDNLPGOO_00567 1.2e-18 K Transcriptional regulator
MDNLPGOO_00568 6.4e-238 pyrP F Permease
MDNLPGOO_00569 1.3e-126 lacR K DeoR C terminal sensor domain
MDNLPGOO_00570 5.9e-129 glsA 3.5.1.2 E Belongs to the glutaminase family
MDNLPGOO_00571 8.1e-111 3.6.1.27 I Acid phosphatase homologues
MDNLPGOO_00572 3e-20 pepC 3.4.22.40 E Peptidase C1-like family
MDNLPGOO_00573 9.3e-99 gadC E Contains amino acid permease domain
MDNLPGOO_00574 3.7e-31 gadC E Contains amino acid permease domain
MDNLPGOO_00575 9.7e-217 mdtG EGP Major facilitator Superfamily
MDNLPGOO_00576 6.4e-31
MDNLPGOO_00577 2.3e-69 K helix_turn_helix multiple antibiotic resistance protein
MDNLPGOO_00578 2.1e-76
MDNLPGOO_00579 6.6e-209 pepA E M42 glutamyl aminopeptidase
MDNLPGOO_00580 1.5e-110 ybbL S ABC transporter, ATP-binding protein
MDNLPGOO_00581 2.8e-129 ybbM S Uncharacterised protein family (UPF0014)
MDNLPGOO_00582 1.3e-60 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
MDNLPGOO_00583 4.9e-59 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
MDNLPGOO_00584 8.4e-134 L PFAM transposase IS3 IS911 family protein
MDNLPGOO_00585 2.7e-95 2.4.2.3 F Phosphorylase superfamily
MDNLPGOO_00586 1.9e-77 ant 2.7.7.47 S PFAM DNA polymerase beta domain protein region
MDNLPGOO_00587 3.6e-16 S Chloramphenicol phosphotransferase-like protein
MDNLPGOO_00588 6e-199 L transposition, DNA-mediated
MDNLPGOO_00589 9.4e-94 cca 2.7.7.19, 2.7.7.72 J Aminoglycoside-2''-adenylyltransferase
MDNLPGOO_00590 7.3e-26 S Psort location Cytoplasmic, score
MDNLPGOO_00591 1e-20 2.7.1.191 G PTS system fructose IIA component
MDNLPGOO_00592 5e-265 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
MDNLPGOO_00593 4.6e-199 L COG2826 Transposase and inactivated derivatives, IS30 family
MDNLPGOO_00594 3.3e-175 lacI3 K helix_turn _helix lactose operon repressor
MDNLPGOO_00595 1.1e-281 dtpT U amino acid peptide transporter
MDNLPGOO_00596 7.8e-185 pipD E Peptidase family C69
MDNLPGOO_00597 4.4e-217 naiP EGP Major facilitator Superfamily
MDNLPGOO_00598 6.5e-151 S Alpha beta hydrolase
MDNLPGOO_00599 3e-67 K Transcriptional regulator, MarR family
MDNLPGOO_00600 3.8e-291 XK27_09600 V ABC transporter, ATP-binding protein
MDNLPGOO_00601 0.0 V ABC transporter transmembrane region
MDNLPGOO_00602 4.6e-146 glnH ET ABC transporter
MDNLPGOO_00603 8.8e-136 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MDNLPGOO_00604 3.4e-149 glnH ET ABC transporter
MDNLPGOO_00605 2.4e-110 gluC P ABC transporter permease
MDNLPGOO_00606 5.7e-107 glnP P ABC transporter permease
MDNLPGOO_00607 2.5e-65
MDNLPGOO_00608 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
MDNLPGOO_00609 7.3e-127 treR K UTRA
MDNLPGOO_00610 0.0 treB 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MDNLPGOO_00612 9.8e-38 padC Q Phenolic acid decarboxylase
MDNLPGOO_00613 5.7e-27 padC Q Phenolic acid decarboxylase
MDNLPGOO_00614 6e-54 padR K Virulence activator alpha C-term
MDNLPGOO_00615 4.1e-75 S Putative adhesin
MDNLPGOO_00616 8.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
MDNLPGOO_00618 1.4e-160 S CAAX protease self-immunity
MDNLPGOO_00619 9.2e-53 S Enterocin A Immunity
MDNLPGOO_00621 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
MDNLPGOO_00622 4.3e-09 rssA S Phospholipase, patatin family
MDNLPGOO_00623 3.9e-252 glnPH2 P ABC transporter permease
MDNLPGOO_00624 2.3e-128 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MDNLPGOO_00625 1.1e-95 K Acetyltransferase (GNAT) domain
MDNLPGOO_00626 1.5e-158 pstS P Phosphate
MDNLPGOO_00627 1.2e-161 pstC P probably responsible for the translocation of the substrate across the membrane
MDNLPGOO_00628 3.1e-156 pstA P Phosphate transport system permease protein PstA
MDNLPGOO_00629 9.1e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MDNLPGOO_00630 4e-142 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MDNLPGOO_00631 5.4e-108 phoU P Plays a role in the regulation of phosphate uptake
MDNLPGOO_00632 3.1e-59 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDNLPGOO_00633 4.6e-280 S C4-dicarboxylate anaerobic carrier
MDNLPGOO_00634 2.6e-85 dps P Belongs to the Dps family
MDNLPGOO_00635 1.2e-155 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MDNLPGOO_00636 1.3e-125 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MDNLPGOO_00637 1.7e-173 rihB 3.2.2.1 F Nucleoside
MDNLPGOO_00638 3.4e-132 gntR K UbiC transcription regulator-associated domain protein
MDNLPGOO_00639 3.8e-45 S Enterocin A Immunity
MDNLPGOO_00640 1.9e-136 glcR K DeoR C terminal sensor domain
MDNLPGOO_00641 1e-22 yceE Q phosphatase activity
MDNLPGOO_00642 3.8e-12 yceE S haloacid dehalogenase-like hydrolase
MDNLPGOO_00643 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
MDNLPGOO_00644 5.2e-116 C nitroreductase
MDNLPGOO_00645 1.2e-31
MDNLPGOO_00646 4.6e-199 L COG2826 Transposase and inactivated derivatives, IS30 family
MDNLPGOO_00647 1.1e-90
MDNLPGOO_00648 1.1e-237 yhdP S Transporter associated domain
MDNLPGOO_00649 3.4e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MDNLPGOO_00650 4.1e-229 potE E amino acid
MDNLPGOO_00651 4.2e-135 M Glycosyl hydrolases family 25
MDNLPGOO_00652 8.6e-205 yfmL 3.6.4.13 L DEAD DEAH box helicase
MDNLPGOO_00653 9.5e-250 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDNLPGOO_00656 5.2e-212 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MDNLPGOO_00657 1e-87 gtcA S Teichoic acid glycosylation protein
MDNLPGOO_00658 1.2e-76 fld C Flavodoxin
MDNLPGOO_00659 7.4e-160 map 3.4.11.18 E Methionine Aminopeptidase
MDNLPGOO_00660 8.7e-162 yihY S Belongs to the UPF0761 family
MDNLPGOO_00661 2.4e-167 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MDNLPGOO_00662 7.5e-180 E ABC transporter, ATP-binding protein
MDNLPGOO_00663 2.6e-283 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MDNLPGOO_00664 5.3e-66 O OsmC-like protein
MDNLPGOO_00665 1.4e-81 ltrA S Bacterial low temperature requirement A protein (LtrA)
MDNLPGOO_00666 2.8e-22 ltrA S Bacterial low temperature requirement A protein (LtrA)
MDNLPGOO_00667 1.1e-112 2.7.6.5 T Region found in RelA / SpoT proteins
MDNLPGOO_00668 4e-116 K response regulator
MDNLPGOO_00669 4.6e-225 sptS 2.7.13.3 T Histidine kinase
MDNLPGOO_00670 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MDNLPGOO_00671 0.0 pepN 3.4.11.2 E aminopeptidase
MDNLPGOO_00672 1.8e-136 S haloacid dehalogenase-like hydrolase
MDNLPGOO_00674 6.1e-283 V ABC transporter transmembrane region
MDNLPGOO_00675 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MDNLPGOO_00676 1.8e-69
MDNLPGOO_00677 5.1e-105 fic D Fic/DOC family
MDNLPGOO_00678 2.4e-139 ppm1 GT2 M Glycosyl transferase family 2
MDNLPGOO_00679 1.9e-90 S Domain of unknown function (DUF4811)
MDNLPGOO_00680 8.9e-265 lmrB EGP Major facilitator Superfamily
MDNLPGOO_00681 1.6e-76 K MerR HTH family regulatory protein
MDNLPGOO_00682 7.6e-64 oppA E ABC transporter substrate-binding protein
MDNLPGOO_00683 3.4e-76 oppA E ABC transporter substrate-binding protein
MDNLPGOO_00684 4e-111 oppA E ABC transporter substrate-binding protein
MDNLPGOO_00685 1.6e-61 pdxH S Pyridoxamine 5'-phosphate oxidase
MDNLPGOO_00686 3.2e-250 pepC 3.4.22.40 E Peptidase C1-like family
MDNLPGOO_00687 3.3e-27 rhaS6 K helix_turn_helix, arabinose operon control protein
MDNLPGOO_00688 5e-170 I Carboxylesterase family
MDNLPGOO_00689 2.7e-308 S Predicted membrane protein (DUF2207)
MDNLPGOO_00690 1.7e-122 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
MDNLPGOO_00691 1.2e-52
MDNLPGOO_00692 7e-142 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
MDNLPGOO_00693 2.2e-91 S ECF-type riboflavin transporter, S component
MDNLPGOO_00694 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
MDNLPGOO_00695 3.7e-56
MDNLPGOO_00696 1.8e-11
MDNLPGOO_00697 3.4e-215 S Uncharacterized protein conserved in bacteria (DUF2325)
MDNLPGOO_00698 1.2e-149 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MDNLPGOO_00699 3e-57 arsC 1.20.4.1 P Belongs to the ArsC family
MDNLPGOO_00700 2e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
MDNLPGOO_00701 2.8e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MDNLPGOO_00702 3.2e-198 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MDNLPGOO_00703 3.1e-101 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MDNLPGOO_00704 8.2e-73 yqhY S Asp23 family, cell envelope-related function
MDNLPGOO_00705 3.6e-67 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MDNLPGOO_00706 7.9e-149 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MDNLPGOO_00707 9.8e-250 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MDNLPGOO_00708 1.1e-34 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MDNLPGOO_00709 3.5e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MDNLPGOO_00710 1.3e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MDNLPGOO_00711 9.7e-292 recN L May be involved in recombinational repair of damaged DNA
MDNLPGOO_00712 1e-47
MDNLPGOO_00713 8.1e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
MDNLPGOO_00714 2.3e-31 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MDNLPGOO_00715 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MDNLPGOO_00716 4.3e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MDNLPGOO_00717 8.4e-238 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MDNLPGOO_00718 2.7e-140 stp 3.1.3.16 T phosphatase
MDNLPGOO_00719 0.0 KLT serine threonine protein kinase
MDNLPGOO_00720 3.6e-160 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MDNLPGOO_00721 2e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MDNLPGOO_00722 2.7e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
MDNLPGOO_00723 1.2e-25 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MDNLPGOO_00724 1.4e-57 asp S Asp23 family, cell envelope-related function
MDNLPGOO_00725 7.6e-305 yloV S DAK2 domain fusion protein YloV
MDNLPGOO_00726 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MDNLPGOO_00727 3.5e-180 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MDNLPGOO_00728 2.2e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MDNLPGOO_00729 2.6e-191 oppD P Belongs to the ABC transporter superfamily
MDNLPGOO_00730 4.6e-177 oppF P Belongs to the ABC transporter superfamily
MDNLPGOO_00731 1.6e-177 oppB P ABC transporter permease
MDNLPGOO_00732 1.5e-161 oppC P Binding-protein-dependent transport system inner membrane component
MDNLPGOO_00733 0.0 oppA E ABC transporter substrate-binding protein
MDNLPGOO_00734 0.0 oppA E ABC transporter substrate-binding protein
MDNLPGOO_00735 5e-122 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MDNLPGOO_00736 0.0 smc D Required for chromosome condensation and partitioning
MDNLPGOO_00737 5e-166 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MDNLPGOO_00738 1.5e-285 pipD E Dipeptidase
MDNLPGOO_00739 4.9e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MDNLPGOO_00740 1.1e-227 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MDNLPGOO_00741 6.4e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MDNLPGOO_00742 3.1e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MDNLPGOO_00743 6.5e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MDNLPGOO_00744 1e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MDNLPGOO_00745 2.3e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MDNLPGOO_00746 1.9e-71 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
MDNLPGOO_00747 3.3e-115 ung2 3.2.2.27 L Uracil-DNA glycosylase
MDNLPGOO_00748 1e-113 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MDNLPGOO_00749 2.1e-33 ynzC S UPF0291 protein
MDNLPGOO_00750 1.9e-30 yneF S Uncharacterised protein family (UPF0154)
MDNLPGOO_00751 0.0 mdlA V ABC transporter
MDNLPGOO_00752 1.4e-283 mdlB V ABC transporter
MDNLPGOO_00753 5.7e-230 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
MDNLPGOO_00754 1.1e-115 plsC 2.3.1.51 I Acyltransferase
MDNLPGOO_00755 1.4e-192 yabB 2.1.1.223 L Methyltransferase small domain
MDNLPGOO_00756 1.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
MDNLPGOO_00757 9.1e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MDNLPGOO_00758 2.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MDNLPGOO_00759 2.6e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MDNLPGOO_00760 8.5e-136 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MDNLPGOO_00761 1.5e-138 cdsA 2.7.7.41 S Belongs to the CDS family
MDNLPGOO_00762 2.3e-229 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
MDNLPGOO_00763 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MDNLPGOO_00764 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MDNLPGOO_00765 8e-82 rimP J Required for maturation of 30S ribosomal subunits
MDNLPGOO_00766 7.5e-214 nusA K Participates in both transcription termination and antitermination
MDNLPGOO_00767 1.5e-46 ylxR K Protein of unknown function (DUF448)
MDNLPGOO_00768 7.1e-47 rplGA J ribosomal protein
MDNLPGOO_00769 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MDNLPGOO_00770 3.5e-61 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MDNLPGOO_00771 6.3e-165 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MDNLPGOO_00772 1.1e-172 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MDNLPGOO_00773 3.7e-274 lsa S ABC transporter
MDNLPGOO_00774 1.1e-94 S GyrI-like small molecule binding domain
MDNLPGOO_00775 9.4e-192 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MDNLPGOO_00776 8.5e-78 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MDNLPGOO_00777 0.0 dnaK O Heat shock 70 kDa protein
MDNLPGOO_00778 3.7e-173 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MDNLPGOO_00779 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MDNLPGOO_00780 6.7e-122 srtA 3.4.22.70 M sortase family
MDNLPGOO_00781 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MDNLPGOO_00782 7e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MDNLPGOO_00783 1.3e-274 yjeM E Amino Acid
MDNLPGOO_00784 3.4e-280 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MDNLPGOO_00785 4.2e-183 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MDNLPGOO_00786 4.5e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MDNLPGOO_00787 1.9e-250 G Major Facilitator
MDNLPGOO_00788 0.0 mgtA 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
MDNLPGOO_00789 9e-153 lysR5 K LysR substrate binding domain
MDNLPGOO_00790 2.6e-41 L Helix-turn-helix domain
MDNLPGOO_00791 3.1e-102 L PFAM Integrase catalytic region
MDNLPGOO_00793 5e-102 3.6.1.27 I Acid phosphatase homologues
MDNLPGOO_00794 6.2e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MDNLPGOO_00795 4.4e-11 S Sugar efflux transporter for intercellular exchange
MDNLPGOO_00796 3.3e-305 ybiT S ABC transporter, ATP-binding protein
MDNLPGOO_00797 3.2e-186 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MDNLPGOO_00798 2.8e-46 K Helix-turn-helix domain
MDNLPGOO_00799 4.4e-139 F DNA/RNA non-specific endonuclease
MDNLPGOO_00800 2.3e-53 L nuclease
MDNLPGOO_00801 1.1e-153 metQ1 P Belongs to the nlpA lipoprotein family
MDNLPGOO_00802 2.5e-184 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MDNLPGOO_00803 1.8e-66 metI P ABC transporter permease
MDNLPGOO_00804 1e-265 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MDNLPGOO_00805 3.7e-257 frdC 1.3.5.4 C FAD binding domain
MDNLPGOO_00806 8.3e-168 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MDNLPGOO_00807 7.3e-245 yjjP S Putative threonine/serine exporter
MDNLPGOO_00808 2.1e-188 ansA 3.5.1.1 EJ L-asparaginase, type I
MDNLPGOO_00809 0.0 aha1 P E1-E2 ATPase
MDNLPGOO_00810 6.5e-304 S Bacterial membrane protein, YfhO
MDNLPGOO_00811 3.4e-67 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MDNLPGOO_00812 1.4e-170 prmA J Ribosomal protein L11 methyltransferase
MDNLPGOO_00813 3e-63
MDNLPGOO_00814 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MDNLPGOO_00815 1.3e-73 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MDNLPGOO_00816 8.9e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
MDNLPGOO_00817 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MDNLPGOO_00818 8.3e-221 patA 2.6.1.1 E Aminotransferase
MDNLPGOO_00819 4.3e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MDNLPGOO_00820 1.7e-134 E GDSL-like Lipase/Acylhydrolase family
MDNLPGOO_00822 1.6e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MDNLPGOO_00823 4.5e-155 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MDNLPGOO_00824 2.7e-120 sdaAB 4.3.1.17 E Serine dehydratase beta chain
MDNLPGOO_00825 3.6e-152 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MDNLPGOO_00826 4.9e-51 S Iron-sulfur cluster assembly protein
MDNLPGOO_00827 7.3e-155 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MDNLPGOO_00828 1.5e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MDNLPGOO_00829 2.9e-33 yqeY S YqeY-like protein
MDNLPGOO_00830 2e-172 phoH T phosphate starvation-inducible protein PhoH
MDNLPGOO_00831 2.4e-79 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MDNLPGOO_00832 4.8e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MDNLPGOO_00833 4.4e-135 recO L Involved in DNA repair and RecF pathway recombination
MDNLPGOO_00834 2.7e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MDNLPGOO_00835 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MDNLPGOO_00836 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MDNLPGOO_00837 6.4e-199 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MDNLPGOO_00838 1.1e-113
MDNLPGOO_00839 6.1e-88
MDNLPGOO_00841 9.2e-174 M domain protein
MDNLPGOO_00842 8e-157 S DNA/RNA non-specific endonuclease
MDNLPGOO_00843 3.8e-114 papP P ABC transporter, permease protein
MDNLPGOO_00844 1.7e-106 P ABC transporter permease
MDNLPGOO_00845 3.4e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MDNLPGOO_00846 1.2e-136 cjaA ET ABC transporter substrate-binding protein
MDNLPGOO_00847 9e-111 trmK 2.1.1.217 S SAM-dependent methyltransferase
MDNLPGOO_00848 4.3e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MDNLPGOO_00849 4.6e-246 pepT 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MDNLPGOO_00850 2.4e-57 yvoA_1 K Transcriptional regulator, GntR family
MDNLPGOO_00851 6.9e-122 skfE V ATPases associated with a variety of cellular activities
MDNLPGOO_00852 2.4e-142
MDNLPGOO_00853 5.8e-136
MDNLPGOO_00854 4.7e-22
MDNLPGOO_00855 7e-101 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MDNLPGOO_00856 9.5e-127
MDNLPGOO_00857 5.3e-173
MDNLPGOO_00858 1.6e-263 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
MDNLPGOO_00859 1.5e-50 ybjQ S Belongs to the UPF0145 family
MDNLPGOO_00860 3.9e-166 XK27_05540 S DUF218 domain
MDNLPGOO_00861 1.1e-144 yxeH S hydrolase
MDNLPGOO_00862 1.2e-296 I Protein of unknown function (DUF2974)
MDNLPGOO_00863 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MDNLPGOO_00864 3.8e-128 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MDNLPGOO_00865 8.3e-168 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MDNLPGOO_00866 8.7e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MDNLPGOO_00867 2e-180 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MDNLPGOO_00868 9.2e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MDNLPGOO_00869 5.6e-208 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MDNLPGOO_00870 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MDNLPGOO_00871 1.8e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MDNLPGOO_00872 1.6e-105 pncA Q Isochorismatase family
MDNLPGOO_00873 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MDNLPGOO_00874 1.3e-144 M Glycosyl transferases group 1
MDNLPGOO_00875 4.1e-08
MDNLPGOO_00876 0.0 pepO 3.4.24.71 O Peptidase family M13
MDNLPGOO_00877 1.5e-10 drgA C nitroreductase
MDNLPGOO_00878 1.4e-53 drgA C nitroreductase
MDNLPGOO_00879 4.9e-28 S SnoaL-like domain
MDNLPGOO_00880 7.7e-200 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MDNLPGOO_00881 6.2e-133 qmcA O prohibitin homologues
MDNLPGOO_00882 1.6e-182 P ABC transporter
MDNLPGOO_00883 4.3e-281 V ABC-type multidrug transport system, ATPase and permease components
MDNLPGOO_00884 3.8e-62
MDNLPGOO_00885 3e-67 C nitroreductase
MDNLPGOO_00886 1.1e-175 V ABC transporter transmembrane region
MDNLPGOO_00887 2e-68 V ABC transporter transmembrane region
MDNLPGOO_00888 5.4e-23
MDNLPGOO_00889 7.7e-105 speG J Acetyltransferase (GNAT) domain
MDNLPGOO_00890 1.9e-56
MDNLPGOO_00891 3.9e-70 K Acetyltransferase (GNAT) domain
MDNLPGOO_00892 2.4e-80 FG HIT domain
MDNLPGOO_00893 8.2e-87 S Protein of unknown function (DUF2785)
MDNLPGOO_00894 5.2e-47 S MazG-like family
MDNLPGOO_00895 3.2e-59
MDNLPGOO_00896 1.4e-118 3.1.3.48 T Tyrosine phosphatase family
MDNLPGOO_00897 2.9e-39
MDNLPGOO_00898 4.3e-255 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MDNLPGOO_00899 1.4e-09 aroD S Serine hydrolase (FSH1)
MDNLPGOO_00900 3.5e-91 aroD S Serine hydrolase (FSH1)
MDNLPGOO_00901 8.7e-88 rimL J Acetyltransferase (GNAT) domain
MDNLPGOO_00902 7.1e-86 2.3.1.57 K Acetyltransferase (GNAT) family
MDNLPGOO_00903 2e-26
MDNLPGOO_00904 1.9e-79
MDNLPGOO_00906 1.3e-45 3.6.1.55 F NUDIX domain
MDNLPGOO_00907 2.3e-115 2.4.2.3 F Phosphorylase superfamily
MDNLPGOO_00908 3.1e-139 2.4.2.3 F Phosphorylase superfamily
MDNLPGOO_00909 5.8e-74 6.3.3.2 S ASCH
MDNLPGOO_00910 1.9e-40 5.4.2.11 G Phosphoglycerate mutase family
MDNLPGOO_00911 4.2e-28 5.4.2.11 G Phosphoglycerate mutase family
MDNLPGOO_00912 4.6e-149 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MDNLPGOO_00913 1.4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MDNLPGOO_00914 2.1e-160 rbsU U ribose uptake protein RbsU
MDNLPGOO_00915 2.2e-148 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
MDNLPGOO_00916 3e-202 G Transmembrane secretion effector
MDNLPGOO_00917 4.3e-281 V ABC-type multidrug transport system, ATPase and permease components
MDNLPGOO_00918 9.5e-273 V ABC-type multidrug transport system, ATPase and permease components
MDNLPGOO_00919 1.4e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MDNLPGOO_00920 4.3e-200 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
MDNLPGOO_00921 8.1e-174 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
MDNLPGOO_00922 2.2e-165 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
MDNLPGOO_00923 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MDNLPGOO_00924 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MDNLPGOO_00925 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MDNLPGOO_00926 4.5e-88 ypmB S Protein conserved in bacteria
MDNLPGOO_00927 1.2e-257 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
MDNLPGOO_00928 2e-112 dnaD L DnaD domain protein
MDNLPGOO_00929 3.6e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MDNLPGOO_00930 2.6e-41 L Helix-turn-helix domain
MDNLPGOO_00931 3.1e-102 L PFAM Integrase catalytic region
MDNLPGOO_00932 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
MDNLPGOO_00933 6.6e-113 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MDNLPGOO_00934 5.1e-104 ypsA S Belongs to the UPF0398 family
MDNLPGOO_00935 4.9e-70 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MDNLPGOO_00936 1.1e-214 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MDNLPGOO_00937 5.9e-238 cpdA S Calcineurin-like phosphoesterase
MDNLPGOO_00938 1.1e-208 I transferase activity, transferring acyl groups other than amino-acyl groups
MDNLPGOO_00939 6.5e-173 degV S DegV family
MDNLPGOO_00940 1.6e-55
MDNLPGOO_00941 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
MDNLPGOO_00942 3.7e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MDNLPGOO_00943 2.5e-169 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MDNLPGOO_00944 4.5e-194 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MDNLPGOO_00945 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
MDNLPGOO_00946 0.0 FbpA K Fibronectin-binding protein
MDNLPGOO_00947 9.3e-63
MDNLPGOO_00948 2.2e-162 degV S EDD domain protein, DegV family
MDNLPGOO_00949 2.5e-150
MDNLPGOO_00950 2.8e-109 K Transcriptional regulator
MDNLPGOO_00951 8.6e-20 K Transcriptional regulator
MDNLPGOO_00952 2.9e-201 xerS L Belongs to the 'phage' integrase family
MDNLPGOO_00953 8.8e-122 yoaK S Protein of unknown function (DUF1275)
MDNLPGOO_00954 1.3e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MDNLPGOO_00955 2.1e-227 L COG3547 Transposase and inactivated derivatives
MDNLPGOO_00956 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
MDNLPGOO_00957 2.8e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
MDNLPGOO_00958 2.6e-100 K Transcriptional regulator
MDNLPGOO_00959 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MDNLPGOO_00960 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MDNLPGOO_00961 3.7e-114 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MDNLPGOO_00962 7.8e-106 lacA 2.3.1.79 S Transferase hexapeptide repeat
MDNLPGOO_00963 5.9e-22 akr5f 1.1.1.346 S reductase
MDNLPGOO_00964 3.7e-45 akr5f 1.1.1.346 S reductase
MDNLPGOO_00965 1.3e-23 akr5f 1.1.1.346 S reductase
MDNLPGOO_00966 2e-88 ybhL S Belongs to the BI1 family
MDNLPGOO_00967 6.5e-32
MDNLPGOO_00968 2e-13 4.1.1.45 S Amidohydrolase
MDNLPGOO_00969 3.1e-234 yrvN L AAA C-terminal domain
MDNLPGOO_00970 1e-111 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
MDNLPGOO_00971 3.8e-79 K GNAT family
MDNLPGOO_00972 1.3e-35 XK27_00915 C Luciferase-like monooxygenase
MDNLPGOO_00973 1.1e-50 XK27_00915 C Luciferase-like monooxygenase
MDNLPGOO_00975 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
MDNLPGOO_00976 1.8e-73 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
MDNLPGOO_00977 2e-153 L Belongs to the 'phage' integrase family
MDNLPGOO_00978 1.4e-63 3.1.21.3 V Type I restriction modification DNA specificity domain
MDNLPGOO_00979 8.6e-309 hsdM 2.1.1.72 V type I restriction-modification system
MDNLPGOO_00980 5.4e-150 L helicase
MDNLPGOO_00981 0.0 S Protein of unknown function DUF262
MDNLPGOO_00982 1.7e-159
MDNLPGOO_00983 6.8e-140 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
MDNLPGOO_00984 9.7e-63 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
MDNLPGOO_00985 6.2e-43 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
MDNLPGOO_00986 3.2e-29 yphH S Cupin domain
MDNLPGOO_00987 2.5e-86 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MDNLPGOO_00988 6.4e-54 1.14.99.57 S Antibiotic biosynthesis monooxygenase
MDNLPGOO_00990 1.3e-175 XK27_00915 C Luciferase-like monooxygenase
MDNLPGOO_00991 0.0 uvrA3 L excinuclease ABC, A subunit
MDNLPGOO_00992 2e-136 S PFAM Archaeal ATPase
MDNLPGOO_00993 9.2e-29 S PFAM Archaeal ATPase
MDNLPGOO_00994 1e-38 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
MDNLPGOO_00995 2.5e-135 H Nodulation protein S (NodS)
MDNLPGOO_00996 4.1e-105 mntH P H( )-stimulated, divalent metal cation uptake system
MDNLPGOO_00997 3.2e-93 mntH P H( )-stimulated, divalent metal cation uptake system
MDNLPGOO_00998 6.2e-54 yitW S Iron-sulfur cluster assembly protein
MDNLPGOO_00999 3.4e-274 sufB O assembly protein SufB
MDNLPGOO_01000 6.1e-79 nifU C SUF system FeS assembly protein, NifU family
MDNLPGOO_01001 2.1e-230 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MDNLPGOO_01002 7.8e-227 sufD O FeS assembly protein SufD
MDNLPGOO_01003 1.4e-144 sufC O FeS assembly ATPase SufC
MDNLPGOO_01004 2e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MDNLPGOO_01005 9.4e-167 aspC 2.6.1.1 E Aminotransferase
MDNLPGOO_01006 3.5e-146 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MDNLPGOO_01007 2.2e-165 L Transposase
MDNLPGOO_01008 1.4e-23
MDNLPGOO_01009 1.6e-63 L PFAM IS66 Orf2 family protein
MDNLPGOO_01010 8.7e-34 S Transposase C of IS166 homeodomain
MDNLPGOO_01011 3.7e-246 L Transposase IS66 family
MDNLPGOO_01012 0.0 UW LPXTG-motif cell wall anchor domain protein
MDNLPGOO_01013 4.3e-63 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MDNLPGOO_01014 5.6e-245 brnQ U Component of the transport system for branched-chain amino acids
MDNLPGOO_01015 1.6e-60 S Putative adhesin
MDNLPGOO_01016 3.1e-37 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
MDNLPGOO_01017 5.2e-11 S Peptidase propeptide and YPEB domain
MDNLPGOO_01018 5.7e-60 S Peptidase propeptide and YPEB domain
MDNLPGOO_01019 6.1e-52 T Transcriptional regulatory protein, C terminal
MDNLPGOO_01020 4.6e-199 L COG2826 Transposase and inactivated derivatives, IS30 family
MDNLPGOO_01021 2.6e-117 3.6.1.55 F NUDIX domain
MDNLPGOO_01022 2.4e-107 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MDNLPGOO_01024 2.2e-31 S reductase
MDNLPGOO_01025 1e-128 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
MDNLPGOO_01026 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MDNLPGOO_01027 4.5e-82 XK26_02160 S Pyridoxamine 5'-phosphate oxidase
MDNLPGOO_01028 1.3e-177 MA20_14895 S Conserved hypothetical protein 698
MDNLPGOO_01029 1.5e-203 L Putative transposase DNA-binding domain
MDNLPGOO_01030 7.2e-72
MDNLPGOO_01032 1.2e-100 S LexA-binding, inner membrane-associated putative hydrolase
MDNLPGOO_01033 1.4e-94 K LysR substrate binding domain
MDNLPGOO_01034 3.2e-177 lacX 5.1.3.3 G Aldose 1-epimerase
MDNLPGOO_01035 2.4e-251 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MDNLPGOO_01036 4.3e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MDNLPGOO_01037 7.5e-169 xerC D Phage integrase, N-terminal SAM-like domain
MDNLPGOO_01038 2.6e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MDNLPGOO_01039 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MDNLPGOO_01040 2.6e-152 dprA LU DNA protecting protein DprA
MDNLPGOO_01041 1.4e-133 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MDNLPGOO_01042 2.7e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MDNLPGOO_01043 1.5e-261 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
MDNLPGOO_01044 1.6e-35 yozE S Belongs to the UPF0346 family
MDNLPGOO_01045 6.3e-146 DegV S Uncharacterised protein, DegV family COG1307
MDNLPGOO_01046 5.8e-115 hlyIII S protein, hemolysin III
MDNLPGOO_01047 1.1e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MDNLPGOO_01048 1.9e-161 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MDNLPGOO_01049 1e-61 2.5.1.74 H UbiA prenyltransferase family
MDNLPGOO_01050 0.0 L Helicase C-terminal domain protein
MDNLPGOO_01051 3.7e-54 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
MDNLPGOO_01052 6.3e-19
MDNLPGOO_01053 4.6e-124 K SIR2-like domain
MDNLPGOO_01054 4.8e-125 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
MDNLPGOO_01055 9e-254 hsdM 2.1.1.72 V type I restriction-modification system
MDNLPGOO_01056 1.5e-42 S RloB-like protein
MDNLPGOO_01057 4.1e-136 S AAA domain, putative AbiEii toxin, Type IV TA system
MDNLPGOO_01058 0.0 hsdR 3.1.21.3 L DEAD/DEAH box helicase
MDNLPGOO_01059 3.6e-230 S Tetratricopeptide repeat protein
MDNLPGOO_01060 6.7e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MDNLPGOO_01061 5.3e-245 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MDNLPGOO_01062 4.3e-217 rpsA 1.17.7.4 J Ribosomal protein S1
MDNLPGOO_01063 2.1e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MDNLPGOO_01064 7.8e-95 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MDNLPGOO_01065 4.3e-61 M Lysin motif
MDNLPGOO_01066 1.2e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MDNLPGOO_01067 1.7e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MDNLPGOO_01068 1.4e-133 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MDNLPGOO_01069 2e-61 ribT K acetyltransferase
MDNLPGOO_01070 7e-164 xerD D recombinase XerD
MDNLPGOO_01071 4.4e-166 cvfB S S1 domain
MDNLPGOO_01072 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MDNLPGOO_01073 4e-181 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MDNLPGOO_01074 0.0 dnaE 2.7.7.7 L DNA polymerase
MDNLPGOO_01075 2e-26 S Protein of unknown function (DUF2929)
MDNLPGOO_01076 2.7e-304 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
MDNLPGOO_01077 1e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MDNLPGOO_01078 7.5e-47 yrvD S Lipopolysaccharide assembly protein A domain
MDNLPGOO_01079 1.8e-142 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MDNLPGOO_01080 1.2e-177 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MDNLPGOO_01081 0.0 oatA I Acyltransferase
MDNLPGOO_01082 2.7e-241 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MDNLPGOO_01083 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MDNLPGOO_01084 2.7e-174 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
MDNLPGOO_01085 1e-89 dedA 3.1.3.1 S SNARE associated Golgi protein
MDNLPGOO_01086 4.8e-148 xerD L Phage integrase, N-terminal SAM-like domain
MDNLPGOO_01087 1.9e-98 GM NmrA-like family
MDNLPGOO_01088 1.3e-85 yagE E amino acid
MDNLPGOO_01090 4.1e-86 S Rib/alpha-like repeat
MDNLPGOO_01091 1.1e-65 S Domain of unknown function DUF1828
MDNLPGOO_01092 1e-66
MDNLPGOO_01093 2.3e-198 L COG2826 Transposase and inactivated derivatives, IS30 family
MDNLPGOO_01094 1.3e-34
MDNLPGOO_01095 1.1e-77 mutT 3.6.1.55 F NUDIX domain
MDNLPGOO_01096 1.4e-65
MDNLPGOO_01099 4.3e-60
MDNLPGOO_01100 2.5e-74
MDNLPGOO_01101 4.5e-61
MDNLPGOO_01102 8.9e-63 S Phage gp6-like head-tail connector protein
MDNLPGOO_01103 1.9e-26
MDNLPGOO_01104 2.1e-227 L COG3547 Transposase and inactivated derivatives
MDNLPGOO_01105 1.3e-17 S YjcQ protein
MDNLPGOO_01107 6.7e-129 S Phage Mu protein F like protein
MDNLPGOO_01109 9.6e-147 S Phage integrase family
MDNLPGOO_01110 1.2e-139 dnaQ 2.7.7.7 L CRISPR-associated protein (Cas_Cas2CT1978)
MDNLPGOO_01111 3.5e-166 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MDNLPGOO_01112 2.7e-117 casE S CRISPR_assoc
MDNLPGOO_01113 2.4e-66 casD S CRISPR-associated protein (Cas_Cas5)
MDNLPGOO_01114 7.5e-115 casC L CT1975-like protein
MDNLPGOO_01115 5.5e-32 casB S CRISPR-associated protein Cse2 (CRISPR_cse2)
MDNLPGOO_01116 1.6e-145 casA L the current gene model (or a revised gene model) may contain a frame shift
MDNLPGOO_01117 3.4e-286 cas3 L CRISPR-associated helicase cas3
MDNLPGOO_01118 1.8e-143 htpX O Peptidase family M48
MDNLPGOO_01119 3.7e-70 S HIRAN
MDNLPGOO_01121 6.9e-203 L COG2826 Transposase and inactivated derivatives, IS30 family
MDNLPGOO_01124 6.7e-89 KQ helix_turn_helix, mercury resistance
MDNLPGOO_01125 7.2e-93 KQ helix_turn_helix, mercury resistance
MDNLPGOO_01126 0.0 O Subtilase family
MDNLPGOO_01127 5.6e-189 O Holliday junction DNA helicase ruvB N-terminus
MDNLPGOO_01128 2.6e-225
MDNLPGOO_01129 6.9e-72 L COG3547 Transposase and inactivated derivatives
MDNLPGOO_01130 3.8e-156
MDNLPGOO_01131 8.6e-230 L Transposase DDE domain
MDNLPGOO_01133 4.6e-199 L COG2826 Transposase and inactivated derivatives, IS30 family
MDNLPGOO_01134 1.4e-82 S AAA ATPase domain
MDNLPGOO_01135 7.7e-188 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MDNLPGOO_01136 6.7e-118 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MDNLPGOO_01137 2.2e-165 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MDNLPGOO_01138 7.8e-207 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MDNLPGOO_01139 4.6e-14 U protein tetramerization
MDNLPGOO_01141 4.1e-21
MDNLPGOO_01142 3.4e-219 KQ helix_turn_helix, mercury resistance
MDNLPGOO_01144 6.4e-94 prrC S Protein conserved in bacteria
MDNLPGOO_01145 1.4e-39 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MDNLPGOO_01146 1.2e-35 S Protein of unknown function (DUF3037)
MDNLPGOO_01147 1e-31
MDNLPGOO_01149 4.3e-173 L AAA domain
MDNLPGOO_01150 1.2e-123 L AAA domain
MDNLPGOO_01151 3.6e-25 S dextransucrase activity
MDNLPGOO_01152 1.1e-153 caiT U Belongs to the BCCT transporter (TC 2.A.15) family
MDNLPGOO_01153 2.8e-78 M Nucleotidyl transferase
MDNLPGOO_01154 1.6e-196 licA 2.7.1.89 M Nucleotidyl transferase
MDNLPGOO_01155 3.2e-12 S dextransucrase activity
MDNLPGOO_01156 1.1e-169 S Membrane protein involved in the export of O-antigen and teichoic acid
MDNLPGOO_01157 4e-218 1.1.1.22 M UDP binding domain
MDNLPGOO_01158 1.9e-22 cysE_1 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
MDNLPGOO_01159 2.8e-33
MDNLPGOO_01160 6.8e-54 S Glycosyltransferase like family 2
MDNLPGOO_01161 2e-208 glf 5.4.99.9 M UDP-galactopyranose mutase
MDNLPGOO_01162 3.5e-77 licD M LicD family
MDNLPGOO_01163 1.7e-88 glfT1 1.1.1.133 S Glycosyltransferase like family 2
MDNLPGOO_01164 6.1e-109 M Glycosyltransferase
MDNLPGOO_01165 3.4e-95 S Glycosyltransferase like family 2
MDNLPGOO_01166 2.1e-132 cps1D M Domain of unknown function (DUF4422)
MDNLPGOO_01167 3e-119 rfbP M Bacterial sugar transferase
MDNLPGOO_01168 3e-139 ywqE 3.1.3.48 GM PHP domain protein
MDNLPGOO_01169 1.4e-123 ywqD 2.7.10.1 D Capsular exopolysaccharide family
MDNLPGOO_01170 3.1e-132 epsB M biosynthesis protein
MDNLPGOO_01171 2.6e-151 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MDNLPGOO_01172 3.8e-42 K DNA-templated transcription, initiation
MDNLPGOO_01173 1.6e-62 frnE Q DSBA-like thioredoxin domain
MDNLPGOO_01174 3.8e-216
MDNLPGOO_01175 2.2e-08 S Domain of unknown function (DUF4767)
MDNLPGOO_01176 7.6e-77 frnE Q DSBA-like thioredoxin domain
MDNLPGOO_01177 9.2e-17 frnE Q DSBA-like thioredoxin domain
MDNLPGOO_01178 1.6e-75
MDNLPGOO_01179 1.8e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MDNLPGOO_01180 1.9e-101 engB D Necessary for normal cell division and for the maintenance of normal septation
MDNLPGOO_01181 5e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MDNLPGOO_01182 2.7e-204 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MDNLPGOO_01183 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MDNLPGOO_01184 1.4e-158
MDNLPGOO_01185 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MDNLPGOO_01186 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MDNLPGOO_01187 7.5e-34 rpsT J Binds directly to 16S ribosomal RNA
MDNLPGOO_01188 3.4e-175 holA 2.7.7.7 L DNA polymerase III delta subunit
MDNLPGOO_01189 0.0 comEC S Competence protein ComEC
MDNLPGOO_01190 5.9e-78 comEA L Competence protein ComEA
MDNLPGOO_01191 6.9e-184 ylbL T Belongs to the peptidase S16 family
MDNLPGOO_01192 6.2e-85 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MDNLPGOO_01193 1.6e-94 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
MDNLPGOO_01194 7.4e-50 ylbG S UPF0298 protein
MDNLPGOO_01195 7.3e-209 ftsW D Belongs to the SEDS family
MDNLPGOO_01196 0.0 typA T GTP-binding protein TypA
MDNLPGOO_01197 5.2e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MDNLPGOO_01198 2.3e-34 ykzG S Belongs to the UPF0356 family
MDNLPGOO_01199 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MDNLPGOO_01200 6.9e-39 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
MDNLPGOO_01201 9.7e-18 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
MDNLPGOO_01202 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MDNLPGOO_01203 3.7e-114 S Repeat protein
MDNLPGOO_01204 1.7e-122 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
MDNLPGOO_01205 1.5e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MDNLPGOO_01206 2.8e-57 XK27_04120 S Putative amino acid metabolism
MDNLPGOO_01207 4e-212 iscS 2.8.1.7 E Aminotransferase class V
MDNLPGOO_01208 2e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MDNLPGOO_01209 5.1e-31
MDNLPGOO_01210 4.8e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
MDNLPGOO_01211 2.3e-33 cspA K 'Cold-shock' DNA-binding domain
MDNLPGOO_01212 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MDNLPGOO_01213 5.3e-115 gpsB D DivIVA domain protein
MDNLPGOO_01214 1.1e-144 ylmH S S4 domain protein
MDNLPGOO_01215 1.3e-26 yggT S YGGT family
MDNLPGOO_01216 1.3e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MDNLPGOO_01217 1.5e-242 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MDNLPGOO_01218 6e-239 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MDNLPGOO_01219 8.4e-151 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MDNLPGOO_01220 2.6e-208 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MDNLPGOO_01221 3.4e-258 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MDNLPGOO_01222 7.7e-177 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MDNLPGOO_01223 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
MDNLPGOO_01224 1.4e-54 ftsL D Cell division protein FtsL
MDNLPGOO_01225 7.1e-178 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MDNLPGOO_01226 4.1e-77 mraZ K Belongs to the MraZ family
MDNLPGOO_01227 4.6e-52 S Protein of unknown function (DUF3397)
MDNLPGOO_01228 3.6e-13 S Protein of unknown function (DUF4044)
MDNLPGOO_01229 1.7e-93 mreD
MDNLPGOO_01230 4.4e-139 mreC M Involved in formation and maintenance of cell shape
MDNLPGOO_01231 2.7e-164 mreB D cell shape determining protein MreB
MDNLPGOO_01232 2.1e-111 radC L DNA repair protein
MDNLPGOO_01233 3e-122 S Haloacid dehalogenase-like hydrolase
MDNLPGOO_01234 2.5e-231 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MDNLPGOO_01235 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MDNLPGOO_01236 0.0 3.6.3.8 P P-type ATPase
MDNLPGOO_01237 1e-172 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
MDNLPGOO_01238 2.6e-121 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MDNLPGOO_01239 3.2e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MDNLPGOO_01240 6.6e-215 iscS2 2.8.1.7 E Aminotransferase class V
MDNLPGOO_01241 4.6e-289 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MDNLPGOO_01243 1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MDNLPGOO_01244 1.7e-81 yueI S Protein of unknown function (DUF1694)
MDNLPGOO_01245 6.4e-235 rarA L recombination factor protein RarA
MDNLPGOO_01247 5.2e-81 usp6 T universal stress protein
MDNLPGOO_01248 1.2e-222 rodA D Belongs to the SEDS family
MDNLPGOO_01249 6.6e-34 S Protein of unknown function (DUF2969)
MDNLPGOO_01250 2.6e-51 yidD S Could be involved in insertion of integral membrane proteins into the membrane
MDNLPGOO_01251 6.8e-13 S DNA-directed RNA polymerase subunit beta
MDNLPGOO_01252 1.7e-179 mbl D Cell shape determining protein MreB Mrl
MDNLPGOO_01253 2.4e-31 ywzB S Protein of unknown function (DUF1146)
MDNLPGOO_01254 1.1e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MDNLPGOO_01255 2.8e-247 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MDNLPGOO_01256 1.2e-169 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MDNLPGOO_01257 6.7e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MDNLPGOO_01258 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MDNLPGOO_01259 3.1e-52 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MDNLPGOO_01260 4.7e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MDNLPGOO_01261 5e-128 atpB C it plays a direct role in the translocation of protons across the membrane
MDNLPGOO_01262 2.6e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MDNLPGOO_01263 2e-183 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MDNLPGOO_01264 5.1e-156 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MDNLPGOO_01265 5e-196 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MDNLPGOO_01266 2.7e-111 tdk 2.7.1.21 F thymidine kinase
MDNLPGOO_01267 8.7e-259 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
MDNLPGOO_01268 1e-190 ampC V Beta-lactamase
MDNLPGOO_01269 3e-106 sip L Belongs to the 'phage' integrase family
MDNLPGOO_01270 4.7e-25 K Transcriptional
MDNLPGOO_01271 4.3e-10 S Helix-turn-helix domain
MDNLPGOO_01274 5e-28
MDNLPGOO_01275 4.2e-139 S DNA primase
MDNLPGOO_01277 4.3e-11
MDNLPGOO_01278 1.5e-10 S Transcriptional regulator, RinA family
MDNLPGOO_01281 1.8e-67
MDNLPGOO_01282 1.7e-52 EGP Major facilitator Superfamily
MDNLPGOO_01283 1.3e-77 EGP Major facilitator Superfamily
MDNLPGOO_01284 5.7e-45 EGP Major facilitator Superfamily
MDNLPGOO_01285 1.9e-261 pgi 5.3.1.9 G Belongs to the GPI family
MDNLPGOO_01286 1.4e-104 vanZ V VanZ like family
MDNLPGOO_01287 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MDNLPGOO_01288 8.7e-265 T PhoQ Sensor
MDNLPGOO_01289 2.9e-128 K Transcriptional regulatory protein, C terminal
MDNLPGOO_01290 3e-66 S SdpI/YhfL protein family
MDNLPGOO_01291 6.4e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
MDNLPGOO_01292 3.1e-212 patB 4.4.1.8 E Aminotransferase, class I
MDNLPGOO_01293 7.6e-23 M Protein of unknown function (DUF3737)
MDNLPGOO_01294 2.1e-57 M Protein of unknown function (DUF3737)
MDNLPGOO_01295 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
MDNLPGOO_01297 5.6e-225 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MDNLPGOO_01298 4.6e-180 ytxK 2.1.1.72 L N-6 DNA Methylase
MDNLPGOO_01299 4e-84 comGF U Putative Competence protein ComGF
MDNLPGOO_01301 7e-58
MDNLPGOO_01302 2.8e-40 comGC U Required for transformation and DNA binding
MDNLPGOO_01303 1.9e-173 comGB NU type II secretion system
MDNLPGOO_01304 1.4e-178 comGA NU Type II IV secretion system protein
MDNLPGOO_01305 1.5e-132 yebC K Transcriptional regulatory protein
MDNLPGOO_01306 4.7e-96 S VanZ like family
MDNLPGOO_01307 1.5e-214 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MDNLPGOO_01308 1e-162 znuA P Belongs to the bacterial solute-binding protein 9 family
MDNLPGOO_01309 1.5e-141 yisY 1.11.1.10 S Alpha/beta hydrolase family
MDNLPGOO_01310 3.8e-112
MDNLPGOO_01311 3e-194 S Putative adhesin
MDNLPGOO_01312 5.9e-61 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MDNLPGOO_01313 7.7e-67 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MDNLPGOO_01314 1.7e-148 S Sucrose-6F-phosphate phosphohydrolase
MDNLPGOO_01315 4.5e-255 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MDNLPGOO_01316 1.4e-170 ybbR S YbbR-like protein
MDNLPGOO_01317 6.5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MDNLPGOO_01318 4.3e-208 potD P ABC transporter
MDNLPGOO_01319 2.9e-137 potC P ABC transporter permease
MDNLPGOO_01320 2.1e-130 potB P ABC transporter permease
MDNLPGOO_01321 2.7e-202 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MDNLPGOO_01322 9e-167 murB 1.3.1.98 M Cell wall formation
MDNLPGOO_01323 1.2e-99 dnaQ 2.7.7.7 L DNA polymerase III
MDNLPGOO_01324 2.2e-84 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
MDNLPGOO_01325 1.2e-177 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MDNLPGOO_01326 2.8e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MDNLPGOO_01327 6.3e-154 ycsE S Sucrose-6F-phosphate phosphohydrolase
MDNLPGOO_01328 5.8e-94
MDNLPGOO_01329 7.1e-77
MDNLPGOO_01330 1.4e-104 3.2.2.20 K acetyltransferase
MDNLPGOO_01331 2.5e-77 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MDNLPGOO_01332 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MDNLPGOO_01333 1.9e-28 secG U Preprotein translocase
MDNLPGOO_01334 4e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MDNLPGOO_01335 1.1e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MDNLPGOO_01336 1e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MDNLPGOO_01337 3.2e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MDNLPGOO_01338 1.4e-187 cggR K Putative sugar-binding domain
MDNLPGOO_01340 2.2e-276 ycaM E amino acid
MDNLPGOO_01341 2.1e-100 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MDNLPGOO_01342 1.1e-170 whiA K May be required for sporulation
MDNLPGOO_01343 2.2e-193 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MDNLPGOO_01344 1e-159 rapZ S Displays ATPase and GTPase activities
MDNLPGOO_01345 8.1e-91 S Short repeat of unknown function (DUF308)
MDNLPGOO_01346 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MDNLPGOO_01347 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MDNLPGOO_01348 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MDNLPGOO_01349 3.1e-189 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
MDNLPGOO_01350 5.2e-257 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MDNLPGOO_01351 3.5e-224 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MDNLPGOO_01352 0.0 lacZ 3.2.1.23 G -beta-galactosidase
MDNLPGOO_01353 0.0 lacS G Transporter
MDNLPGOO_01354 2.8e-185 lacR K Transcriptional regulator
MDNLPGOO_01355 3.9e-286 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
MDNLPGOO_01356 1.3e-176 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
MDNLPGOO_01357 7.2e-186 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MDNLPGOO_01358 5.6e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MDNLPGOO_01359 8.2e-185 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MDNLPGOO_01360 9.5e-155 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MDNLPGOO_01361 2.6e-172 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MDNLPGOO_01363 1.2e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MDNLPGOO_01364 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MDNLPGOO_01365 1.3e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MDNLPGOO_01366 5.9e-123 comFC S Competence protein
MDNLPGOO_01367 1.4e-220 comFA L Helicase C-terminal domain protein
MDNLPGOO_01368 1.6e-117 yvyE 3.4.13.9 S YigZ family
MDNLPGOO_01369 3.5e-192 tagO 2.7.8.33, 2.7.8.35 M transferase
MDNLPGOO_01370 1e-197 rny S Endoribonuclease that initiates mRNA decay
MDNLPGOO_01371 1.8e-193 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MDNLPGOO_01372 3e-96 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MDNLPGOO_01373 2.3e-121 ymfM S Helix-turn-helix domain
MDNLPGOO_01374 6e-129 IQ Enoyl-(Acyl carrier protein) reductase
MDNLPGOO_01375 1.8e-226 S Peptidase M16
MDNLPGOO_01376 1.5e-225 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
MDNLPGOO_01377 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MDNLPGOO_01378 4.3e-74 WQ51_03320 S Protein of unknown function (DUF1149)
MDNLPGOO_01379 4.6e-105 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MDNLPGOO_01380 2.8e-205 yubA S AI-2E family transporter
MDNLPGOO_01381 8.6e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
MDNLPGOO_01382 1.1e-200 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
MDNLPGOO_01383 8.3e-232 N Uncharacterized conserved protein (DUF2075)
MDNLPGOO_01384 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
MDNLPGOO_01385 1.4e-167 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MDNLPGOO_01386 2e-149 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MDNLPGOO_01387 5.2e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
MDNLPGOO_01388 1.4e-107 yjbK S CYTH
MDNLPGOO_01389 1.4e-102 yjbH Q Thioredoxin
MDNLPGOO_01390 2.8e-157 coiA 3.6.4.12 S Competence protein
MDNLPGOO_01391 2.1e-117 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MDNLPGOO_01392 4e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MDNLPGOO_01393 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MDNLPGOO_01394 4.2e-40 ptsH G phosphocarrier protein HPR
MDNLPGOO_01395 1.7e-24
MDNLPGOO_01396 0.0 clpE O Belongs to the ClpA ClpB family
MDNLPGOO_01397 1.1e-43 XK27_09445 S Domain of unknown function (DUF1827)
MDNLPGOO_01398 6.7e-303 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MDNLPGOO_01399 1.8e-156 hlyX S Transporter associated domain
MDNLPGOO_01400 8.8e-78
MDNLPGOO_01401 3.9e-87
MDNLPGOO_01402 2e-111 ygaC J Belongs to the UPF0374 family
MDNLPGOO_01403 5.6e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
MDNLPGOO_01404 1.1e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MDNLPGOO_01405 5.4e-217 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
MDNLPGOO_01406 4.9e-216 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
MDNLPGOO_01407 2.4e-212 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
MDNLPGOO_01408 2.8e-179 D Alpha beta
MDNLPGOO_01410 4e-150 S haloacid dehalogenase-like hydrolase
MDNLPGOO_01411 3.7e-205 EGP Major facilitator Superfamily
MDNLPGOO_01412 3.3e-258 glnA 6.3.1.2 E glutamine synthetase
MDNLPGOO_01413 5.3e-167 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MDNLPGOO_01414 8.1e-19 S Protein of unknown function (DUF3042)
MDNLPGOO_01415 4.4e-57 yqhL P Rhodanese-like protein
MDNLPGOO_01416 7.9e-35 yqgQ S Bacterial protein of unknown function (DUF910)
MDNLPGOO_01417 7.9e-115 gluP 3.4.21.105 S Rhomboid family
MDNLPGOO_01418 6e-89 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MDNLPGOO_01419 7.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MDNLPGOO_01420 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
MDNLPGOO_01421 0.0 S membrane
MDNLPGOO_01422 6.9e-65 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MDNLPGOO_01423 1.5e-200 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MDNLPGOO_01424 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MDNLPGOO_01425 1.3e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MDNLPGOO_01426 6.2e-63 yodB K Transcriptional regulator, HxlR family
MDNLPGOO_01427 1.7e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDNLPGOO_01428 5.5e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MDNLPGOO_01429 3.2e-162 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MDNLPGOO_01430 2.9e-266 arlS 2.7.13.3 T Histidine kinase
MDNLPGOO_01431 3.2e-130 K response regulator
MDNLPGOO_01432 2.2e-91 yceD S Uncharacterized ACR, COG1399
MDNLPGOO_01433 6.6e-215 ylbM S Belongs to the UPF0348 family
MDNLPGOO_01434 3.7e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MDNLPGOO_01435 3.9e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
MDNLPGOO_01436 4.5e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MDNLPGOO_01437 1e-209 yqeH S Ribosome biogenesis GTPase YqeH
MDNLPGOO_01438 4e-87 yqeG S HAD phosphatase, family IIIA
MDNLPGOO_01439 8.7e-129 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MDNLPGOO_01440 6.6e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MDNLPGOO_01441 2.4e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MDNLPGOO_01442 4e-87 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MDNLPGOO_01443 7e-29 S Protein of unknown function (DUF3021)
MDNLPGOO_01444 2.3e-31 K LytTr DNA-binding domain
MDNLPGOO_01445 2.1e-227 L COG3547 Transposase and inactivated derivatives
MDNLPGOO_01446 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MDNLPGOO_01447 1.4e-159 dnaI L Primosomal protein DnaI
MDNLPGOO_01448 1.9e-242 dnaB L Replication initiation and membrane attachment
MDNLPGOO_01449 2.3e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MDNLPGOO_01450 6.6e-102 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MDNLPGOO_01451 2.2e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MDNLPGOO_01452 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MDNLPGOO_01453 2e-49
MDNLPGOO_01454 4.4e-152 levD G PTS system mannose/fructose/sorbose family IID component
MDNLPGOO_01455 9.2e-137 M PTS system sorbose-specific iic component
MDNLPGOO_01456 2.1e-93 2.7.1.191 G PTS system sorbose subfamily IIB component
MDNLPGOO_01457 1.4e-72 levA G PTS system fructose IIA component
MDNLPGOO_01458 3.1e-165 rbsB G Periplasmic binding protein domain
MDNLPGOO_01459 2e-215 baeS F Sensor histidine kinase
MDNLPGOO_01460 3.1e-116 baeR K helix_turn_helix, Lux Regulon
MDNLPGOO_01461 3.3e-231 G Bacterial extracellular solute-binding protein
MDNLPGOO_01462 5.5e-127 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MDNLPGOO_01463 6.3e-115 K UTRA
MDNLPGOO_01464 1.1e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MDNLPGOO_01466 1.6e-64 cutC P Participates in the control of copper homeostasis
MDNLPGOO_01467 1.5e-120 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MDNLPGOO_01468 6.2e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MDNLPGOO_01469 9.8e-12
MDNLPGOO_01470 8e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MDNLPGOO_01471 2e-222 ecsB U ABC transporter
MDNLPGOO_01472 1.4e-133 ecsA V ABC transporter, ATP-binding protein
MDNLPGOO_01473 9.2e-77 hit FG Scavenger mRNA decapping enzyme C-term binding
MDNLPGOO_01474 2e-51
MDNLPGOO_01475 2.8e-23 S YtxH-like protein
MDNLPGOO_01476 3e-146 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MDNLPGOO_01477 2.5e-183 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
MDNLPGOO_01478 0.0 L AAA domain
MDNLPGOO_01479 2.7e-214 yhaO L Ser Thr phosphatase family protein
MDNLPGOO_01480 3.6e-55 yheA S Belongs to the UPF0342 family
MDNLPGOO_01481 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MDNLPGOO_01482 5.5e-158 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MDNLPGOO_01484 2.3e-11 adk 2.7.4.3 F adenylate kinase activity
MDNLPGOO_01485 3.3e-141 neo 2.7.1.87, 2.7.1.95 F Belongs to the aminoglycoside phosphotransferase family
MDNLPGOO_01486 3.6e-188 V Beta-lactamase
MDNLPGOO_01487 1.4e-24 ung2 3.2.2.27 L Uracil-DNA glycosylase
MDNLPGOO_01488 1.3e-111 L Resolvase, N terminal domain
MDNLPGOO_01489 1.1e-253 L Probable transposase
MDNLPGOO_01490 2.9e-111 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
MDNLPGOO_01491 1.2e-94 dps P Belongs to the Dps family
MDNLPGOO_01492 4.5e-32 copZ C Heavy-metal-associated domain
MDNLPGOO_01493 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
MDNLPGOO_01494 3.6e-55
MDNLPGOO_01496 2.4e-35 3.1.21.3 V Type I restriction modification DNA specificity domain
MDNLPGOO_01497 1.4e-56 yybR K HxlR-like helix-turn-helix
MDNLPGOO_01498 3.2e-59 algA G Cupin domain
MDNLPGOO_01501 0.0 S Protein of unknown function DUF262
MDNLPGOO_01502 0.0 L Type III restriction enzyme, res subunit
MDNLPGOO_01503 6.9e-115 2.1.1.72, 3.1.21.4 L site-specific DNA-methyltransferase (adenine-specific) activity
MDNLPGOO_01504 4.4e-87 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
MDNLPGOO_01505 4.8e-20 K Cro/C1-type HTH DNA-binding domain
MDNLPGOO_01506 1e-22 L ATPase involved in DNA repair
MDNLPGOO_01507 3e-24 L AAA domain
MDNLPGOO_01508 3.7e-125 L Mrr N-terminal domain
MDNLPGOO_01509 3e-251 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MDNLPGOO_01510 1.1e-119 spaE S ABC-2 family transporter protein
MDNLPGOO_01511 1.4e-127 mutF V ABC transporter, ATP-binding protein
MDNLPGOO_01512 6.6e-230 nhaC C Na H antiporter NhaC
MDNLPGOO_01513 1.6e-205 L Putative transposase DNA-binding domain
MDNLPGOO_01514 1e-71 salL 2.5.1.63, 2.5.1.94 K S-adenosyl-l-methionine hydroxide adenosyltransferase
MDNLPGOO_01515 7.4e-95 S UPF0397 protein
MDNLPGOO_01516 0.0 ykoD P ABC transporter, ATP-binding protein
MDNLPGOO_01517 3.1e-142 cbiQ P cobalt transport
MDNLPGOO_01518 1.8e-117 ybhL S Belongs to the BI1 family
MDNLPGOO_01519 1.5e-141 GT2,GT4 M family 8
MDNLPGOO_01520 3.4e-149 S hydrolase
MDNLPGOO_01522 8.4e-165 yegS 2.7.1.107 G Lipid kinase
MDNLPGOO_01523 6e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MDNLPGOO_01524 2.4e-270 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MDNLPGOO_01525 1.3e-48 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MDNLPGOO_01526 2.2e-207 camS S sex pheromone
MDNLPGOO_01527 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MDNLPGOO_01528 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MDNLPGOO_01529 7e-110 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
MDNLPGOO_01530 3.1e-102 S ECF transporter, substrate-specific component
MDNLPGOO_01532 2.6e-82 ydcK S Belongs to the SprT family
MDNLPGOO_01533 4.2e-132 M Glycosyltransferase sugar-binding region containing DXD motif
MDNLPGOO_01534 2.6e-253 epsU S Polysaccharide biosynthesis protein
MDNLPGOO_01535 2.7e-224 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MDNLPGOO_01536 0.0 pacL 3.6.3.8 P P-type ATPase
MDNLPGOO_01537 2e-296 spoVK O ATPase family associated with various cellular activities (AAA)
MDNLPGOO_01538 5.2e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MDNLPGOO_01539 9.8e-280 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MDNLPGOO_01540 3.8e-145 S Glycosyltransferase like family 2
MDNLPGOO_01541 2.8e-147 S Glycosyltransferase like family 2
MDNLPGOO_01542 2e-200 csaB M Glycosyl transferases group 1
MDNLPGOO_01543 8.5e-131 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MDNLPGOO_01544 7.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
MDNLPGOO_01545 8e-123 gntR1 K UTRA
MDNLPGOO_01546 1.5e-187
MDNLPGOO_01547 6e-51 P Rhodanese Homology Domain
MDNLPGOO_01550 9.9e-166 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
MDNLPGOO_01551 4.5e-112 K SIS domain
MDNLPGOO_01552 1.1e-57 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
MDNLPGOO_01553 1.6e-169 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
MDNLPGOO_01554 2.3e-19 yjgN S Bacterial protein of unknown function (DUF898)
MDNLPGOO_01556 3.3e-81 M LysM domain protein
MDNLPGOO_01557 3.2e-112 M LysM domain protein
MDNLPGOO_01558 8.9e-29 S Putative ABC-transporter type IV
MDNLPGOO_01559 7.5e-57 psiE S Phosphate-starvation-inducible E
MDNLPGOO_01560 6.7e-90 K acetyltransferase
MDNLPGOO_01561 6.6e-141 L Belongs to the 'phage' integrase family
MDNLPGOO_01562 1.2e-10
MDNLPGOO_01563 2.3e-118 repB EP Plasmid replication protein
MDNLPGOO_01565 1.1e-06
MDNLPGOO_01566 1.7e-132 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MDNLPGOO_01567 1.3e-27
MDNLPGOO_01569 1.3e-21
MDNLPGOO_01571 4.4e-10 S Bacteriophage abortive infection AbiH
MDNLPGOO_01572 4.6e-199 L COG2826 Transposase and inactivated derivatives, IS30 family
MDNLPGOO_01574 1.9e-47 dcm 2.1.1.37 H cytosine-specific methyltransferase
MDNLPGOO_01575 1.4e-125 M domain protein
MDNLPGOO_01577 4.9e-69
MDNLPGOO_01579 6.3e-162 yvgN C Aldo keto reductase
MDNLPGOO_01580 3.5e-244 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
MDNLPGOO_01581 1.1e-77 S Uncharacterized protein conserved in bacteria (DUF2263)
MDNLPGOO_01582 1.7e-190 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MDNLPGOO_01583 0.0 lhr L DEAD DEAH box helicase
MDNLPGOO_01584 2.8e-249 P P-loop Domain of unknown function (DUF2791)
MDNLPGOO_01585 0.0 S TerB-C domain
MDNLPGOO_01586 5.8e-105 4.1.1.44 S Carboxymuconolactone decarboxylase family
MDNLPGOO_01588 7e-66
MDNLPGOO_01589 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MDNLPGOO_01590 1.8e-243 cycA E Amino acid permease
MDNLPGOO_01592 2.5e-15 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
MDNLPGOO_01593 9.1e-23 S ORF located using Blastx
MDNLPGOO_01594 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MDNLPGOO_01595 1.9e-181 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MDNLPGOO_01596 1.4e-195 cpoA GT4 M Glycosyltransferase, group 1 family protein
MDNLPGOO_01597 7.1e-217 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
MDNLPGOO_01609 1.3e-47
MDNLPGOO_01626 2.5e-15 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
MDNLPGOO_01627 9.1e-23 S ORF located using Blastx
MDNLPGOO_01628 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MDNLPGOO_01629 1.9e-181 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MDNLPGOO_01630 1.4e-195 cpoA GT4 M Glycosyltransferase, group 1 family protein
MDNLPGOO_01631 7.1e-217 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
MDNLPGOO_01643 1.3e-47
MDNLPGOO_01660 2.5e-15 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
MDNLPGOO_01661 9.1e-23 S ORF located using Blastx
MDNLPGOO_01662 4.2e-218 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MDNLPGOO_01663 1.2e-100 J Acetyltransferase (GNAT) domain
MDNLPGOO_01664 5.3e-107 yjbF S SNARE associated Golgi protein
MDNLPGOO_01665 5e-153 I alpha/beta hydrolase fold
MDNLPGOO_01666 2.8e-154 hipB K Helix-turn-helix
MDNLPGOO_01667 9.2e-256 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
MDNLPGOO_01668 8.2e-177
MDNLPGOO_01669 3.2e-124 S SNARE associated Golgi protein
MDNLPGOO_01670 1.5e-141 cof S haloacid dehalogenase-like hydrolase
MDNLPGOO_01671 0.0 ydgH S MMPL family
MDNLPGOO_01672 2.3e-96 yobS K Bacterial regulatory proteins, tetR family
MDNLPGOO_01673 3.8e-160 3.5.2.6 V Beta-lactamase enzyme family
MDNLPGOO_01674 2e-166 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
MDNLPGOO_01675 6.5e-78 yjcF S Acetyltransferase (GNAT) domain
MDNLPGOO_01676 4.1e-87 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
MDNLPGOO_01677 4.1e-75 yybA 2.3.1.57 K Transcriptional regulator
MDNLPGOO_01678 3.4e-48 ypaA S Protein of unknown function (DUF1304)
MDNLPGOO_01679 1.8e-237 G Bacterial extracellular solute-binding protein
MDNLPGOO_01680 1.8e-248 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
MDNLPGOO_01681 1.2e-146 gtsC P Binding-protein-dependent transport system inner membrane component
MDNLPGOO_01682 2.1e-157 gtsB P ABC-type sugar transport systems, permease components
MDNLPGOO_01683 4.6e-202 malK P ATPases associated with a variety of cellular activities
MDNLPGOO_01684 4e-275 pipD E Dipeptidase
MDNLPGOO_01685 6.4e-202 L Putative transposase DNA-binding domain
MDNLPGOO_01686 7.4e-155 endA F DNA RNA non-specific endonuclease
MDNLPGOO_01687 9e-158 dkg S reductase
MDNLPGOO_01688 3e-181 dnaQ 2.7.7.7 L EXOIII
MDNLPGOO_01689 5.7e-149 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MDNLPGOO_01690 3.7e-111 yviA S Protein of unknown function (DUF421)
MDNLPGOO_01691 8.3e-73 S Protein of unknown function (DUF3290)
MDNLPGOO_01692 3.2e-239 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MDNLPGOO_01693 4.3e-92 S PAS domain
MDNLPGOO_01694 2e-143 pnuC H nicotinamide mononucleotide transporter
MDNLPGOO_01695 9.8e-43 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MDNLPGOO_01696 9e-133 S PAS domain
MDNLPGOO_01697 2e-234 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MDNLPGOO_01698 1.1e-46 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
MDNLPGOO_01699 4.4e-43 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
MDNLPGOO_01700 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MDNLPGOO_01701 1.2e-132 ksgA 2.1.1.182, 2.1.1.184 J Ribosomal RNA adenine dimethylase
MDNLPGOO_01702 1.6e-26 S Omega Transcriptional Repressor
MDNLPGOO_01703 1.9e-144 G PTS system mannose/fructose/sorbose family IID component
MDNLPGOO_01704 3.6e-127 G PTS system sorbose-specific iic component
MDNLPGOO_01705 3e-162 2.7.1.191 G PTS system sorbose subfamily IIB component
MDNLPGOO_01706 0.0 oppA E ABC transporter substrate-binding protein
MDNLPGOO_01707 1.8e-151 EG EamA-like transporter family
MDNLPGOO_01708 1.4e-270 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MDNLPGOO_01709 2e-151 bglP 2.7.1.211 G phosphotransferase system
MDNLPGOO_01710 6e-123 licT K CAT RNA binding domain
MDNLPGOO_01711 8.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MDNLPGOO_01712 1.9e-163 coaA 2.7.1.33 F Pantothenic acid kinase
MDNLPGOO_01713 2.3e-104 E GDSL-like Lipase/Acylhydrolase
MDNLPGOO_01714 4.8e-123 yvpB S Peptidase_C39 like family
MDNLPGOO_01715 0.0 helD 3.6.4.12 L DNA helicase
MDNLPGOO_01716 5.1e-116 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
MDNLPGOO_01718 0.0 3.6.3.8 P ATPase, P-type (transporting), HAD superfamily, subfamily IC
MDNLPGOO_01719 4.3e-130 rpiR1 K Helix-turn-helix domain, rpiR family
MDNLPGOO_01720 3.1e-127 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MDNLPGOO_01721 1.3e-49 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
MDNLPGOO_01722 1.6e-24 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
MDNLPGOO_01723 1.1e-41
MDNLPGOO_01724 2.8e-26
MDNLPGOO_01725 1e-124 pgm3 G Phosphoglycerate mutase family
MDNLPGOO_01726 1.2e-306 V FtsX-like permease family
MDNLPGOO_01727 6.3e-134 cysA V ABC transporter, ATP-binding protein
MDNLPGOO_01728 6.9e-278 E amino acid
MDNLPGOO_01729 7.7e-121 V ABC-2 type transporter
MDNLPGOO_01730 4.2e-122 V Transport permease protein
MDNLPGOO_01731 7e-136 V ABC transporter
MDNLPGOO_01732 1.3e-74
MDNLPGOO_01734 1.2e-228 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MDNLPGOO_01735 1.6e-227 S Putative peptidoglycan binding domain
MDNLPGOO_01736 8.8e-112 M NlpC P60 family protein
MDNLPGOO_01737 7.1e-98 gmk2 2.7.4.8 F Guanylate kinase
MDNLPGOO_01738 5.3e-44
MDNLPGOO_01739 4.3e-262 S O-antigen ligase like membrane protein
MDNLPGOO_01740 4.5e-109
MDNLPGOO_01741 2.5e-80 nrdI F Belongs to the NrdI family
MDNLPGOO_01742 1.8e-173 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MDNLPGOO_01743 2.6e-80
MDNLPGOO_01744 3.3e-28 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
MDNLPGOO_01745 3.2e-37
MDNLPGOO_01746 3.1e-78 S Threonine/Serine exporter, ThrE
MDNLPGOO_01747 9.2e-136 thrE S Putative threonine/serine exporter
MDNLPGOO_01748 1.7e-282 S ABC transporter
MDNLPGOO_01749 1.4e-60
MDNLPGOO_01750 1.5e-37
MDNLPGOO_01751 1.2e-208 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MDNLPGOO_01752 0.0 pepF E oligoendopeptidase F
MDNLPGOO_01753 2e-256 lctP C L-lactate permease
MDNLPGOO_01754 1.5e-133 znuB U ABC 3 transport family
MDNLPGOO_01755 3.8e-114 fhuC P ABC transporter
MDNLPGOO_01756 3e-154 psaA P Belongs to the bacterial solute-binding protein 9 family
MDNLPGOO_01757 2.1e-42 K helix_turn_helix, Arsenical Resistance Operon Repressor
MDNLPGOO_01758 1.5e-138 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
MDNLPGOO_01759 7.8e-148 2.7.7.7 M domain protein
MDNLPGOO_01760 9.1e-73 2.7.7.7 M domain protein
MDNLPGOO_01761 0.0 fruA 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
MDNLPGOO_01762 4.5e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MDNLPGOO_01763 4.4e-135 fruR K DeoR C terminal sensor domain
MDNLPGOO_01764 3.1e-102 L PFAM Integrase catalytic region
MDNLPGOO_01765 2.6e-41 L Helix-turn-helix domain
MDNLPGOO_01766 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
MDNLPGOO_01767 4e-218 natB CP ABC-2 family transporter protein
MDNLPGOO_01768 4.4e-166 natA S ABC transporter, ATP-binding protein
MDNLPGOO_01769 3.4e-143 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
MDNLPGOO_01770 1.1e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MDNLPGOO_01771 2.7e-200 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
MDNLPGOO_01772 7.4e-121 K response regulator
MDNLPGOO_01773 0.0 V ABC transporter
MDNLPGOO_01774 8.7e-296 V ABC transporter, ATP-binding protein
MDNLPGOO_01775 5e-148 XK27_01040 S Protein of unknown function (DUF1129)
MDNLPGOO_01776 3.4e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MDNLPGOO_01777 2.9e-43 yyzM S Bacterial protein of unknown function (DUF951)
MDNLPGOO_01778 1.6e-152 spo0J K Belongs to the ParB family
MDNLPGOO_01779 9.7e-138 soj D Sporulation initiation inhibitor
MDNLPGOO_01780 2e-142 noc K Belongs to the ParB family
MDNLPGOO_01781 1.5e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
MDNLPGOO_01782 7.1e-95 cvpA S Colicin V production protein
MDNLPGOO_01783 3.6e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MDNLPGOO_01784 1.4e-147 3.1.3.48 T Tyrosine phosphatase family
MDNLPGOO_01785 1.1e-200 4.2.1.126 S Bacterial protein of unknown function (DUF871)
MDNLPGOO_01786 1.4e-98 azr 1.5.1.36 S NADPH-dependent FMN reductase
MDNLPGOO_01787 2.1e-94 nqr 1.5.1.36 S reductase
MDNLPGOO_01788 4.6e-106 K WHG domain
MDNLPGOO_01789 3e-37
MDNLPGOO_01790 1.2e-266 pipD E Dipeptidase
MDNLPGOO_01791 1.8e-57 arbB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MDNLPGOO_01792 1.3e-19 K CAT RNA binding domain
MDNLPGOO_01793 1.5e-10 K CAT RNA binding domain
MDNLPGOO_01794 3e-114 devA 3.6.3.25 V ABC transporter, ATP-binding protein
MDNLPGOO_01795 4.5e-178 hrtB V ABC transporter permease
MDNLPGOO_01796 1e-85 ygfC K Bacterial regulatory proteins, tetR family
MDNLPGOO_01797 5.6e-109 G phosphoglycerate mutase
MDNLPGOO_01798 3.6e-114 G Phosphoglycerate mutase family
MDNLPGOO_01799 4e-136 aroD S Alpha/beta hydrolase family
MDNLPGOO_01800 3.6e-137 S Belongs to the UPF0246 family
MDNLPGOO_01801 4.2e-51
MDNLPGOO_01802 1.1e-124
MDNLPGOO_01803 2.1e-155 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MDNLPGOO_01804 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
MDNLPGOO_01805 6e-123 3.4.16.4, 3.5.2.6 V Beta-lactamase enzyme family
MDNLPGOO_01806 6.9e-153 ybbH_2 K Helix-turn-helix domain, rpiR family
MDNLPGOO_01807 4.1e-152 2.7.7.12 C Domain of unknown function (DUF4931)
MDNLPGOO_01808 2.6e-68 aroD 1.1.1.25, 4.2.1.10 E 3-dehydroquinate dehydratase activity
MDNLPGOO_01809 3.2e-153
MDNLPGOO_01810 1.1e-215 mdtG EGP Major facilitator Superfamily
MDNLPGOO_01811 9.2e-124 puuD S peptidase C26
MDNLPGOO_01812 7.1e-292 V ABC transporter transmembrane region
MDNLPGOO_01813 3e-87 ymdB S Macro domain protein
MDNLPGOO_01814 0.0 scrA 2.7.1.199, 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
MDNLPGOO_01815 3e-297 scrB 3.2.1.26 GH32 G invertase
MDNLPGOO_01816 3.6e-185 scrR K Transcriptional regulator, LacI family
MDNLPGOO_01817 2.7e-143 ptp2 3.1.3.48 T Tyrosine phosphatase family
MDNLPGOO_01818 4.6e-146 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MDNLPGOO_01819 2.1e-131 cobQ S glutamine amidotransferase
MDNLPGOO_01820 2.4e-256 yfnA E Amino Acid
MDNLPGOO_01821 4e-159 EG EamA-like transporter family
MDNLPGOO_01822 8.4e-190 asnA 6.3.1.1 F aspartate--ammonia ligase
MDNLPGOO_01823 5e-233 steT_1 E amino acid
MDNLPGOO_01824 3.8e-136 puuD S peptidase C26
MDNLPGOO_01825 7.3e-220 yifK E Amino acid permease
MDNLPGOO_01826 7.4e-253 yifK E Amino acid permease
MDNLPGOO_01827 1.1e-64 manO S Domain of unknown function (DUF956)
MDNLPGOO_01828 4.9e-168 manN G system, mannose fructose sorbose family IID component
MDNLPGOO_01829 3.7e-124 manY G PTS system
MDNLPGOO_01830 3.4e-183 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
MDNLPGOO_01832 2.5e-15 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
MDNLPGOO_01833 9.1e-23 S ORF located using Blastx
MDNLPGOO_01836 1.5e-250 yfnA E Amino Acid
MDNLPGOO_01837 0.0 clpE2 O AAA domain (Cdc48 subfamily)
MDNLPGOO_01838 3.9e-170 S Alpha/beta hydrolase of unknown function (DUF915)
MDNLPGOO_01839 2.6e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDNLPGOO_01840 7.8e-38
MDNLPGOO_01841 3.4e-214 lmrP E Major Facilitator Superfamily
MDNLPGOO_01842 3.4e-138 pbpX2 V Beta-lactamase
MDNLPGOO_01843 1.4e-250 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MDNLPGOO_01844 3.3e-36 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDNLPGOO_01845 3.3e-233 dltB M MBOAT, membrane-bound O-acyltransferase family
MDNLPGOO_01846 3.4e-288 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDNLPGOO_01848 6.6e-39
MDNLPGOO_01849 8.3e-202 ywhK S Membrane
MDNLPGOO_01851 5.8e-25
MDNLPGOO_01852 5.1e-76 ykuL S (CBS) domain
MDNLPGOO_01853 0.0 cadA P P-type ATPase
MDNLPGOO_01854 5.3e-196 napA P Sodium/hydrogen exchanger family
MDNLPGOO_01855 1e-58 S Putative adhesin
MDNLPGOO_01856 5.2e-263 V ABC transporter transmembrane region
MDNLPGOO_01857 2e-129 mutR K Helix-turn-helix XRE-family like proteins
MDNLPGOO_01858 1e-26
MDNLPGOO_01859 2.2e-59 dam 2.1.1.72 H Site-specific DNA-methyltransferase (adenine-specific)
MDNLPGOO_01860 6.7e-99 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
MDNLPGOO_01861 1.1e-113 K Transcriptional regulator
MDNLPGOO_01862 4.2e-292 M Exporter of polyketide antibiotics
MDNLPGOO_01863 7.4e-169 yjjC V ABC transporter
MDNLPGOO_01864 4.8e-104 L Resolvase, N terminal domain
MDNLPGOO_01865 1.1e-253 L Probable transposase
MDNLPGOO_01866 5.8e-17 ropB K Transcriptional regulator
MDNLPGOO_01867 6.7e-116 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MDNLPGOO_01868 9.5e-156 S Protein of unknown function (DUF979)
MDNLPGOO_01869 9.5e-113 S Protein of unknown function (DUF969)
MDNLPGOO_01870 1.4e-18 S Protein of unknown function (DUF805)
MDNLPGOO_01871 1.2e-16
MDNLPGOO_01872 6.5e-08
MDNLPGOO_01873 1e-265 G PTS system Galactitol-specific IIC component
MDNLPGOO_01874 1.8e-92 S Protein of unknown function (DUF1440)
MDNLPGOO_01875 2.1e-101 S CAAX protease self-immunity
MDNLPGOO_01876 5.8e-200 S DUF218 domain
MDNLPGOO_01877 0.0 macB_3 V ABC transporter, ATP-binding protein
MDNLPGOO_01878 7.3e-269 cydA 1.10.3.14 C ubiquinol oxidase
MDNLPGOO_01879 9.4e-181 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
MDNLPGOO_01880 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MDNLPGOO_01881 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MDNLPGOO_01882 4.2e-172 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
MDNLPGOO_01883 7.9e-225 G Bacterial extracellular solute-binding protein
MDNLPGOO_01884 1.9e-167 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
MDNLPGOO_01885 4.3e-192 tcsA S ABC transporter substrate-binding protein PnrA-like
MDNLPGOO_01886 2.1e-151 blaA6 V Beta-lactamase
MDNLPGOO_01887 4.4e-63 pts29C 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDNLPGOO_01888 9.8e-35 3.5.2.6 V Beta-lactamase enzyme family
MDNLPGOO_01889 3.2e-132 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MDNLPGOO_01890 3.8e-39 S membrane transporter protein
MDNLPGOO_01891 1.6e-157 yeaE S Aldo/keto reductase family
MDNLPGOO_01892 5.1e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MDNLPGOO_01893 2.5e-118 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
MDNLPGOO_01894 3.5e-123 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
MDNLPGOO_01895 1.5e-236 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
MDNLPGOO_01896 3e-232 pbuG S permease
MDNLPGOO_01897 1.6e-126 K helix_turn_helix, mercury resistance
MDNLPGOO_01898 4.4e-231 pbuG S permease
MDNLPGOO_01899 1.7e-45 I bis(5'-adenosyl)-triphosphatase activity
MDNLPGOO_01900 1.2e-225 pbuG S permease
MDNLPGOO_01901 6.4e-71 K Bacteriophage CI repressor helix-turn-helix domain
MDNLPGOO_01902 1.5e-68 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
MDNLPGOO_01903 1.9e-87
MDNLPGOO_01904 1.4e-90
MDNLPGOO_01905 2.1e-73 atkY K Penicillinase repressor
MDNLPGOO_01906 7.8e-64 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MDNLPGOO_01907 1.1e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MDNLPGOO_01908 0.0 copA 3.6.3.54 P P-type ATPase
MDNLPGOO_01909 2.6e-277 E Amino acid permease
MDNLPGOO_01910 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
MDNLPGOO_01911 3.2e-247 ynbB 4.4.1.1 P aluminum resistance
MDNLPGOO_01912 2.1e-227 L COG3547 Transposase and inactivated derivatives
MDNLPGOO_01913 3.1e-62 K Acetyltransferase (GNAT) domain
MDNLPGOO_01914 6.9e-203 L COG2826 Transposase and inactivated derivatives, IS30 family
MDNLPGOO_01915 3.7e-225 EGP Sugar (and other) transporter
MDNLPGOO_01916 4.3e-65 S Iron-sulphur cluster biosynthesis
MDNLPGOO_01917 4.6e-199 L COG2826 Transposase and inactivated derivatives, IS30 family
MDNLPGOO_01918 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MDNLPGOO_01919 1.6e-264 clcA P chloride
MDNLPGOO_01920 1.5e-269 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MDNLPGOO_01921 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MDNLPGOO_01922 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MDNLPGOO_01923 1.4e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MDNLPGOO_01924 6.2e-149 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MDNLPGOO_01925 3.5e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MDNLPGOO_01926 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
MDNLPGOO_01927 2.6e-92 L Helix-turn-helix domain of transposase family ISL3
MDNLPGOO_01928 3.4e-109 L Transposase
MDNLPGOO_01930 9e-94 S Cell surface protein
MDNLPGOO_01932 7.5e-07
MDNLPGOO_01933 3.5e-68 S Lysin motif
MDNLPGOO_01934 4.6e-124 L Replication initiation factor
MDNLPGOO_01935 2.2e-33 L Single-strand binding protein family
MDNLPGOO_01936 7e-89 L Phage integrase, N-terminal SAM-like domain
MDNLPGOO_01938 1.6e-11 S Protein of unknown function (DUF2922)
MDNLPGOO_01940 1.8e-08
MDNLPGOO_01942 1.5e-44 copA 3.6.3.54 P P-type ATPase
MDNLPGOO_01943 2.6e-140 XK27_05540 S DUF218 domain
MDNLPGOO_01944 1.9e-134 ropB K Helix-turn-helix XRE-family like proteins
MDNLPGOO_01945 0.0 pepO 3.4.24.71 O Peptidase family M13
MDNLPGOO_01946 0.0 3.5.1.28 UW LPXTG-motif cell wall anchor domain protein
MDNLPGOO_01947 4.7e-241 L Transposase IS66 family
MDNLPGOO_01948 1.9e-33 S Transposase C of IS166 homeodomain
MDNLPGOO_01949 2.3e-62 L PFAM IS66 Orf2 family protein
MDNLPGOO_01950 1.5e-22
MDNLPGOO_01951 7.1e-200 L COG2826 Transposase and inactivated derivatives, IS30 family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)