ORF_ID e_value Gene_name EC_number CAZy COGs Description
JOAHLMEO_00001 5.8e-227 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
JOAHLMEO_00002 4.6e-39 yugE S Domain of unknown function (DUF1871)
JOAHLMEO_00003 3.2e-155 yugF I Hydrolase
JOAHLMEO_00004 1.6e-85 alaR K Transcriptional regulator
JOAHLMEO_00005 2.1e-199 yugH 2.6.1.1 E Aminotransferase
JOAHLMEO_00006 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
JOAHLMEO_00007 4e-34 yuzA S Domain of unknown function (DUF378)
JOAHLMEO_00008 6.4e-226 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
JOAHLMEO_00009 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JOAHLMEO_00010 7.7e-304 yngK T Glycosyl hydrolase-like 10
JOAHLMEO_00012 9e-26 S Family of unknown function (DUF5367)
JOAHLMEO_00013 9.8e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
JOAHLMEO_00014 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
JOAHLMEO_00015 1.6e-249 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
JOAHLMEO_00016 2.2e-295 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JOAHLMEO_00017 1.4e-95 ywqN S NAD(P)H-dependent
JOAHLMEO_00019 7.6e-89 ywrA P COG2059 Chromate transport protein ChrA
JOAHLMEO_00020 3.5e-103 ywrB P Chromate transporter
JOAHLMEO_00021 8e-82 ywrC K Transcriptional regulator
JOAHLMEO_00022 2.2e-309 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
JOAHLMEO_00023 5e-54 S Domain of unknown function (DUF4181)
JOAHLMEO_00024 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JOAHLMEO_00025 1.6e-54 yphP S Belongs to the UPF0403 family
JOAHLMEO_00026 1e-142 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
JOAHLMEO_00027 2.5e-112 ypjP S YpjP-like protein
JOAHLMEO_00028 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
JOAHLMEO_00029 6.9e-155 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JOAHLMEO_00030 5.7e-94 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JOAHLMEO_00031 1.4e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
JOAHLMEO_00032 4.2e-110 hlyIII S protein, Hemolysin III
JOAHLMEO_00033 4.9e-38 pspF K Transcriptional regulator
JOAHLMEO_00034 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JOAHLMEO_00035 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
JOAHLMEO_00036 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
JOAHLMEO_00037 1.5e-49 yabP S Sporulation protein YabP
JOAHLMEO_00038 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
JOAHLMEO_00039 9.5e-243 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
JOAHLMEO_00040 2.1e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JOAHLMEO_00041 1.5e-92 spoVT K stage V sporulation protein
JOAHLMEO_00042 7.8e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
JOAHLMEO_00043 1.6e-166 yvgK P COG1910 Periplasmic molybdate-binding protein domain
JOAHLMEO_00044 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
JOAHLMEO_00045 3.9e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
JOAHLMEO_00046 7.4e-130 MA20_18170 S membrane transporter protein
JOAHLMEO_00047 3e-284 uxaA 4.2.1.7, 4.4.1.24 G Altronate
JOAHLMEO_00048 7.3e-280 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
JOAHLMEO_00049 1.4e-101 exuR K transcriptional
JOAHLMEO_00050 2.1e-210 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
JOAHLMEO_00051 1.3e-81 mhqR K transcriptional
JOAHLMEO_00052 6.9e-26 ykoL
JOAHLMEO_00053 5.9e-18
JOAHLMEO_00054 1.4e-53 tnrA K transcriptional
JOAHLMEO_00055 2.2e-222 mgtE P Acts as a magnesium transporter
JOAHLMEO_00058 4.9e-85 ykoJ S Peptidase propeptide and YPEB domain
JOAHLMEO_00059 2.4e-111 ykoI S Peptidase propeptide and YPEB domain
JOAHLMEO_00060 1.8e-240 ykoH 2.7.13.3 T Histidine kinase
JOAHLMEO_00061 1.8e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JOAHLMEO_00062 5.7e-109 ykoF S YKOF-related Family
JOAHLMEO_00063 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
JOAHLMEO_00064 6.8e-306 P ABC transporter, ATP-binding protein
JOAHLMEO_00065 2.9e-134 ykoC P Cobalt transport protein
JOAHLMEO_00066 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
JOAHLMEO_00067 1.5e-175 isp O Belongs to the peptidase S8 family
JOAHLMEO_00068 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JOAHLMEO_00069 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
JOAHLMEO_00070 8.4e-72 ohrB O Organic hydroperoxide resistance protein
JOAHLMEO_00071 1.7e-73 ohrR K COG1846 Transcriptional regulators
JOAHLMEO_00072 1.3e-70 ohrA O Organic hydroperoxide resistance protein
JOAHLMEO_00073 1.5e-225 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JOAHLMEO_00074 2e-200 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JOAHLMEO_00075 8.6e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
JOAHLMEO_00076 9.1e-50 ykkD P Multidrug resistance protein
JOAHLMEO_00077 1.7e-54 ykkC P Multidrug resistance protein
JOAHLMEO_00078 1.6e-96 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
JOAHLMEO_00079 2.6e-97 ykkA S Protein of unknown function (DUF664)
JOAHLMEO_00080 3.9e-128 ykjA S Protein of unknown function (DUF421)
JOAHLMEO_00081 1.5e-09
JOAHLMEO_00082 8.1e-224 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JOAHLMEO_00083 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
JOAHLMEO_00084 2.5e-158 ykgA E Amidinotransferase
JOAHLMEO_00085 3.6e-204 pgl 3.1.1.31 G 6-phosphogluconolactonase
JOAHLMEO_00086 8.5e-187 ykfD E Belongs to the ABC transporter superfamily
JOAHLMEO_00087 1.5e-169 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
JOAHLMEO_00088 4.8e-199 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
JOAHLMEO_00089 7.6e-177 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
JOAHLMEO_00091 0.0 dppE E ABC transporter substrate-binding protein
JOAHLMEO_00092 2.7e-188 dppD P Belongs to the ABC transporter superfamily
JOAHLMEO_00093 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JOAHLMEO_00094 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JOAHLMEO_00095 3.3e-152 dppA E D-aminopeptidase
JOAHLMEO_00096 6.3e-135 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
JOAHLMEO_00097 2.6e-210 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JOAHLMEO_00098 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
JOAHLMEO_00099 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JOAHLMEO_00101 6.7e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
JOAHLMEO_00102 4.7e-233 steT E amino acid
JOAHLMEO_00103 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
JOAHLMEO_00104 5.8e-175 pit P phosphate transporter
JOAHLMEO_00105 5.2e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
JOAHLMEO_00106 6.7e-23 spoIISB S Stage II sporulation protein SB
JOAHLMEO_00107 4.5e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
JOAHLMEO_00108 2.7e-39 xhlB S SPP1 phage holin
JOAHLMEO_00109 6.2e-39 xhlA S Haemolysin XhlA
JOAHLMEO_00110 7.5e-152 xepA
JOAHLMEO_00111 5.5e-22 xkdX
JOAHLMEO_00112 2.7e-44 xkdW S XkdW protein
JOAHLMEO_00113 7.2e-179
JOAHLMEO_00114 1.9e-40
JOAHLMEO_00115 1.9e-101 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
JOAHLMEO_00116 9.6e-189 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
JOAHLMEO_00117 4.1e-69 xkdS S Protein of unknown function (DUF2634)
JOAHLMEO_00118 1e-38 xkdR S Protein of unknown function (DUF2577)
JOAHLMEO_00119 3.1e-181 yqbQ 3.2.1.96 G NLP P60 protein
JOAHLMEO_00120 2.7e-118 xkdP S Lysin motif
JOAHLMEO_00121 2.3e-275 xkdO L Transglycosylase SLT domain
JOAHLMEO_00122 1.4e-75 S Phage XkdN-like tail assembly chaperone protein, TAC
JOAHLMEO_00123 1e-75 xkdM S Phage tail tube protein
JOAHLMEO_00124 9.3e-256 xkdK S Phage tail sheath C-terminal domain
JOAHLMEO_00125 1.9e-77 xkdJ
JOAHLMEO_00126 1.1e-86 xkdI S Bacteriophage HK97-gp10, putative tail-component
JOAHLMEO_00127 7.3e-64 yqbH S Domain of unknown function (DUF3599)
JOAHLMEO_00128 6.7e-63 yqbG S Protein of unknown function (DUF3199)
JOAHLMEO_00129 1.7e-168 xkdG S Phage capsid family
JOAHLMEO_00130 5.9e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
JOAHLMEO_00131 3.4e-280 yqbA S portal protein
JOAHLMEO_00132 1.3e-251 xtmB S phage terminase, large subunit
JOAHLMEO_00133 1.4e-139 xtmA L phage terminase small subunit
JOAHLMEO_00134 3.5e-83 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
JOAHLMEO_00135 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
JOAHLMEO_00138 4.1e-118 xkdC L Bacterial dnaA protein
JOAHLMEO_00139 3.9e-156 xkdB K sequence-specific DNA binding
JOAHLMEO_00141 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
JOAHLMEO_00142 2.3e-110 xkdA E IrrE N-terminal-like domain
JOAHLMEO_00143 4.4e-160 ydbD P Catalase
JOAHLMEO_00144 1.8e-110 yjqB S Pfam:DUF867
JOAHLMEO_00145 1.8e-60 yjqA S Bacterial PH domain
JOAHLMEO_00146 2e-169 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
JOAHLMEO_00147 5.3e-40 S YCII-related domain
JOAHLMEO_00149 1e-212 S response regulator aspartate phosphatase
JOAHLMEO_00150 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
JOAHLMEO_00151 2.3e-78 yjoA S DinB family
JOAHLMEO_00152 0.0 L HKD family nuclease
JOAHLMEO_00153 3.5e-59 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
JOAHLMEO_00154 7.8e-115 L COG1112 Superfamily I DNA and RNA helicases and helicase subunits
JOAHLMEO_00155 2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
JOAHLMEO_00156 1.6e-272 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
JOAHLMEO_00157 5.4e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
JOAHLMEO_00158 5e-78 VY92_01935 K acetyltransferase
JOAHLMEO_00159 3.2e-44 aprE 3.4.21.62 O Belongs to the peptidase S8 family
JOAHLMEO_00160 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
JOAHLMEO_00161 6e-112 yjbE P Integral membrane protein TerC family
JOAHLMEO_00162 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
JOAHLMEO_00163 4.9e-41 ybyB
JOAHLMEO_00164 7.1e-211 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
JOAHLMEO_00166 1.9e-115 kapD L the KinA pathway to sporulation
JOAHLMEO_00167 7.4e-70 kapB G Kinase associated protein B
JOAHLMEO_00168 4.6e-233 T PhoQ Sensor
JOAHLMEO_00169 6.7e-181 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
JOAHLMEO_00170 3.2e-178 oxyR3 K LysR substrate binding domain
JOAHLMEO_00171 9e-144 yafE Q ubiE/COQ5 methyltransferase family
JOAHLMEO_00172 3.1e-235 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JOAHLMEO_00173 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JOAHLMEO_00174 1e-10 M Glycosyltransferase like family 2
JOAHLMEO_00179 2e-08
JOAHLMEO_00186 1.3e-09
JOAHLMEO_00187 7.8e-08
JOAHLMEO_00188 1e-199 pbuE EGP Major facilitator Superfamily
JOAHLMEO_00189 9.4e-98 ydhK M Protein of unknown function (DUF1541)
JOAHLMEO_00190 1.5e-180 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
JOAHLMEO_00191 9.5e-83 K Acetyltransferase (GNAT) domain
JOAHLMEO_00193 1.9e-67 frataxin S Domain of unknown function (DU1801)
JOAHLMEO_00194 9e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
JOAHLMEO_00195 6.7e-125
JOAHLMEO_00196 7e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
JOAHLMEO_00197 1.1e-242 ydhD M Glycosyl hydrolase
JOAHLMEO_00198 6.5e-122 ydhC K FCD
JOAHLMEO_00199 1.2e-121 ydhB S membrane transporter protein
JOAHLMEO_00200 2.2e-208 tcaB EGP Major facilitator Superfamily
JOAHLMEO_00201 2.4e-69 ydgJ K Winged helix DNA-binding domain
JOAHLMEO_00202 4e-113 drgA C nitroreductase
JOAHLMEO_00203 0.0 ydgH S drug exporters of the RND superfamily
JOAHLMEO_00204 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
JOAHLMEO_00205 1.4e-87 dinB S DinB family
JOAHLMEO_00206 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
JOAHLMEO_00207 1.9e-300 expZ S ABC transporter
JOAHLMEO_00208 5.5e-83 yycN 2.3.1.128 K Acetyltransferase
JOAHLMEO_00209 1.4e-51 S DoxX-like family
JOAHLMEO_00210 9e-99 K Bacterial regulatory proteins, tetR family
JOAHLMEO_00211 2.5e-32 ydgB S Spore germination protein gerPA/gerPF
JOAHLMEO_00212 9.8e-36 ydgA S Spore germination protein gerPA/gerPF
JOAHLMEO_00213 5.9e-68 cotP O Belongs to the small heat shock protein (HSP20) family
JOAHLMEO_00214 5.8e-121 ydfS S Protein of unknown function (DUF421)
JOAHLMEO_00215 1.7e-89 ydfR S Protein of unknown function (DUF421)
JOAHLMEO_00217 4.4e-30
JOAHLMEO_00218 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
JOAHLMEO_00219 1.7e-54 traF CO Thioredoxin
JOAHLMEO_00220 8.8e-63 mhqP S DoxX
JOAHLMEO_00221 7.6e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
JOAHLMEO_00222 4.4e-21 ydfN C nitroreductase
JOAHLMEO_00223 2.5e-56 ydfN C nitroreductase
JOAHLMEO_00224 6.6e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JOAHLMEO_00225 4.3e-144 K Bacterial transcription activator, effector binding domain
JOAHLMEO_00226 2.7e-115 S Protein of unknown function (DUF554)
JOAHLMEO_00227 1.1e-172 S Alpha/beta hydrolase family
JOAHLMEO_00228 0.0 ydfJ S drug exporters of the RND superfamily
JOAHLMEO_00229 5.5e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JOAHLMEO_00230 5e-178 ydfH 2.7.13.3 T Histidine kinase
JOAHLMEO_00232 5e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JOAHLMEO_00233 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
JOAHLMEO_00234 1.2e-114 ydfE S Flavin reductase like domain
JOAHLMEO_00235 4.6e-274 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JOAHLMEO_00236 3.2e-148 ydfC EG EamA-like transporter family
JOAHLMEO_00237 3.4e-122 T Transcriptional regulatory protein, C terminal
JOAHLMEO_00238 1.7e-212 T GHKL domain
JOAHLMEO_00239 1.5e-158
JOAHLMEO_00240 7e-123 nodB1 G deacetylase
JOAHLMEO_00241 8.3e-149 lytR K Transcriptional regulator
JOAHLMEO_00242 3.7e-145 ydfB J GNAT acetyltransferase
JOAHLMEO_00243 4.8e-230 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JOAHLMEO_00244 6.3e-57 arsR K transcriptional
JOAHLMEO_00245 3.2e-104 ydeS K Transcriptional regulator
JOAHLMEO_00246 1.9e-185 ydeR EGP Major facilitator Superfamily
JOAHLMEO_00247 8.6e-110 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
JOAHLMEO_00248 4.8e-69 ydeP K Transcriptional regulator
JOAHLMEO_00249 2.3e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
JOAHLMEO_00250 3e-56 K HxlR-like helix-turn-helix
JOAHLMEO_00251 1.8e-104 ydeN S Serine hydrolase
JOAHLMEO_00252 6e-73 maoC I N-terminal half of MaoC dehydratase
JOAHLMEO_00253 7.8e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JOAHLMEO_00254 1.8e-153 ydeK EG -transporter
JOAHLMEO_00255 8.8e-85 K Transcriptional regulator C-terminal region
JOAHLMEO_00256 3.7e-15 ptsH G PTS HPr component phosphorylation site
JOAHLMEO_00257 2.8e-30 S SNARE associated Golgi protein
JOAHLMEO_00258 8.5e-98
JOAHLMEO_00259 5.1e-102 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
JOAHLMEO_00260 6.1e-45 ydeH
JOAHLMEO_00261 2.3e-216 ydeG EGP Major facilitator superfamily
JOAHLMEO_00262 6.2e-260 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JOAHLMEO_00263 4.5e-163 ydeE K AraC family transcriptional regulator
JOAHLMEO_00264 8.3e-171 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
JOAHLMEO_00265 2.4e-161 rhaS5 K AraC-like ligand binding domain
JOAHLMEO_00266 1.2e-142 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
JOAHLMEO_00267 2.3e-78 carD K Transcription factor
JOAHLMEO_00268 8.7e-30 cspL K Cold shock
JOAHLMEO_00269 2.4e-192 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
JOAHLMEO_00270 9.6e-40
JOAHLMEO_00271 3.4e-33 K Helix-turn-helix XRE-family like proteins
JOAHLMEO_00272 2.1e-46 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
JOAHLMEO_00273 5e-47 ydeH
JOAHLMEO_00274 6.9e-208 msbA2 3.6.3.44 V ABC transporter
JOAHLMEO_00275 5.8e-211 KLT Protein kinase domain
JOAHLMEO_00282 1.3e-115 KLT Protein kinase domain
JOAHLMEO_00285 1.9e-156 yyaD S Membrane
JOAHLMEO_00286 2.9e-116 yknT
JOAHLMEO_00287 1.1e-119 yuxJ EGP Major facilitator Superfamily
JOAHLMEO_00291 2e-08
JOAHLMEO_00298 7.8e-08
JOAHLMEO_00299 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
JOAHLMEO_00300 6.3e-75 yuxK S protein conserved in bacteria
JOAHLMEO_00301 6.3e-78 yufK S Family of unknown function (DUF5366)
JOAHLMEO_00302 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
JOAHLMEO_00303 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
JOAHLMEO_00304 5.8e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
JOAHLMEO_00305 1e-271 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
JOAHLMEO_00306 2.5e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
JOAHLMEO_00307 7.8e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
JOAHLMEO_00308 8.2e-233 maeN C COG3493 Na citrate symporter
JOAHLMEO_00309 5e-15
JOAHLMEO_00310 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
JOAHLMEO_00311 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
JOAHLMEO_00312 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
JOAHLMEO_00313 2.1e-261 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
JOAHLMEO_00314 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
JOAHLMEO_00315 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
JOAHLMEO_00316 5.7e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
JOAHLMEO_00317 2.3e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
JOAHLMEO_00318 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JOAHLMEO_00319 0.0 comP 2.7.13.3 T Histidine kinase
JOAHLMEO_00321 3e-147 comQ H Polyprenyl synthetase
JOAHLMEO_00323 8.5e-23 yuzC
JOAHLMEO_00324 1.1e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
JOAHLMEO_00325 1.4e-265 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JOAHLMEO_00326 1.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
JOAHLMEO_00327 7.9e-67 yueI S Protein of unknown function (DUF1694)
JOAHLMEO_00328 2.8e-38 yueH S YueH-like protein
JOAHLMEO_00329 6.6e-31 yueG S Spore germination protein gerPA/gerPF
JOAHLMEO_00330 3.2e-190 yueF S transporter activity
JOAHLMEO_00331 2.9e-24 S Protein of unknown function (DUF2642)
JOAHLMEO_00332 4.8e-96 yueE S phosphohydrolase
JOAHLMEO_00333 1.7e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JOAHLMEO_00334 3.3e-64 yueC S Family of unknown function (DUF5383)
JOAHLMEO_00335 0.0 esaA S type VII secretion protein EsaA
JOAHLMEO_00336 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
JOAHLMEO_00337 5.2e-211 essB S WXG100 protein secretion system (Wss), protein YukC
JOAHLMEO_00338 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
JOAHLMEO_00339 2.8e-45 esxA S Belongs to the WXG100 family
JOAHLMEO_00340 1.9e-228 yukF QT Transcriptional regulator
JOAHLMEO_00341 3e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
JOAHLMEO_00342 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
JOAHLMEO_00343 5e-36 mbtH S MbtH-like protein
JOAHLMEO_00344 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JOAHLMEO_00345 9.3e-175 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
JOAHLMEO_00346 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
JOAHLMEO_00347 2.5e-225 entC 5.4.4.2 HQ Isochorismate synthase
JOAHLMEO_00348 7.3e-141 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JOAHLMEO_00349 3.9e-167 besA S Putative esterase
JOAHLMEO_00350 2.4e-120 yuiH S Oxidoreductase molybdopterin binding domain
JOAHLMEO_00351 5.7e-93 bioY S Biotin biosynthesis protein
JOAHLMEO_00352 3.9e-211 yuiF S antiporter
JOAHLMEO_00353 5.8e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JOAHLMEO_00354 1.2e-77 yuiD S protein conserved in bacteria
JOAHLMEO_00355 1e-116 yuiC S protein conserved in bacteria
JOAHLMEO_00356 8.4e-27 yuiB S Putative membrane protein
JOAHLMEO_00357 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
JOAHLMEO_00358 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
JOAHLMEO_00360 1e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
JOAHLMEO_00361 4.2e-115 paiB K Putative FMN-binding domain
JOAHLMEO_00362 6.1e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JOAHLMEO_00363 3.7e-63 erpA S Belongs to the HesB IscA family
JOAHLMEO_00364 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JOAHLMEO_00365 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JOAHLMEO_00366 3.2e-39 yuzB S Belongs to the UPF0349 family
JOAHLMEO_00367 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
JOAHLMEO_00368 1.1e-55 yuzD S protein conserved in bacteria
JOAHLMEO_00369 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
JOAHLMEO_00370 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
JOAHLMEO_00371 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
JOAHLMEO_00372 3.4e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JOAHLMEO_00373 4.6e-241 hom 1.1.1.3 E homoserine dehydrogenase
JOAHLMEO_00374 1e-198 yutH S Spore coat protein
JOAHLMEO_00376 2e-08
JOAHLMEO_00383 2.6e-169 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
JOAHLMEO_00384 1.3e-232 purD 6.3.4.13 F Belongs to the GARS family
JOAHLMEO_00385 3.3e-71 K helix_turn_helix ASNC type
JOAHLMEO_00386 4.1e-226 yjeH E Amino acid permease
JOAHLMEO_00387 6e-27 S Protein of unknown function (DUF2892)
JOAHLMEO_00388 0.0 yerA 3.5.4.2 F adenine deaminase
JOAHLMEO_00389 2.4e-189 yerB S Protein of unknown function (DUF3048) C-terminal domain
JOAHLMEO_00390 4.8e-51 yerC S protein conserved in bacteria
JOAHLMEO_00391 5.7e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
JOAHLMEO_00393 1.9e-124 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
JOAHLMEO_00394 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
JOAHLMEO_00395 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JOAHLMEO_00396 7e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
JOAHLMEO_00397 1e-195 yerI S homoserine kinase type II (protein kinase fold)
JOAHLMEO_00398 1.6e-123 sapB S MgtC SapB transporter
JOAHLMEO_00399 3.2e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JOAHLMEO_00400 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JOAHLMEO_00401 3.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
JOAHLMEO_00402 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JOAHLMEO_00403 8.7e-148 yerO K Transcriptional regulator
JOAHLMEO_00404 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JOAHLMEO_00405 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
JOAHLMEO_00406 1.4e-256 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JOAHLMEO_00407 3.9e-09
JOAHLMEO_00408 7.8e-100
JOAHLMEO_00410 5.3e-100 S response regulator aspartate phosphatase
JOAHLMEO_00412 3.5e-27
JOAHLMEO_00413 1.2e-167 yobL S Bacterial EndoU nuclease
JOAHLMEO_00414 1.8e-176 3.4.24.40 CO amine dehydrogenase activity
JOAHLMEO_00415 5.2e-39
JOAHLMEO_00416 2.2e-210 S Tetratricopeptide repeat
JOAHLMEO_00418 2.7e-126 yeeN K transcriptional regulatory protein
JOAHLMEO_00420 9.4e-101 dhaR3 K Transcriptional regulator
JOAHLMEO_00421 1.8e-80 yesE S SnoaL-like domain
JOAHLMEO_00422 3.8e-143 yesF GM NAD(P)H-binding
JOAHLMEO_00423 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
JOAHLMEO_00424 1.5e-45 cotJB S CotJB protein
JOAHLMEO_00425 5.2e-104 cotJC P Spore Coat
JOAHLMEO_00426 1.3e-101 yesJ K Acetyltransferase (GNAT) family
JOAHLMEO_00428 5.4e-102 yesL S Protein of unknown function, DUF624
JOAHLMEO_00429 0.0 yesM 2.7.13.3 T Histidine kinase
JOAHLMEO_00430 1.6e-202 yesN K helix_turn_helix, arabinose operon control protein
JOAHLMEO_00431 3.3e-247 yesO G Bacterial extracellular solute-binding protein
JOAHLMEO_00432 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
JOAHLMEO_00433 7.7e-163 yesQ P Binding-protein-dependent transport system inner membrane component
JOAHLMEO_00434 1e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
JOAHLMEO_00435 0.0 yesS K Transcriptional regulator
JOAHLMEO_00436 7.2e-132 E GDSL-like Lipase/Acylhydrolase
JOAHLMEO_00437 8.7e-127 yesU S Domain of unknown function (DUF1961)
JOAHLMEO_00438 1e-113 yesV S Protein of unknown function, DUF624
JOAHLMEO_00439 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
JOAHLMEO_00440 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
JOAHLMEO_00441 1.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
JOAHLMEO_00442 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
JOAHLMEO_00443 0.0 yetA
JOAHLMEO_00444 6.9e-289 lplA G Bacterial extracellular solute-binding protein
JOAHLMEO_00445 1.9e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
JOAHLMEO_00446 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
JOAHLMEO_00447 3.2e-253 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
JOAHLMEO_00448 4e-122 yetF S membrane
JOAHLMEO_00449 8.2e-54 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
JOAHLMEO_00450 5.7e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JOAHLMEO_00451 6.4e-35
JOAHLMEO_00452 2.4e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
JOAHLMEO_00453 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
JOAHLMEO_00454 9.1e-105 yetJ S Belongs to the BI1 family
JOAHLMEO_00455 6.2e-53 yetL K helix_turn_helix multiple antibiotic resistance protein
JOAHLMEO_00456 3.1e-198 yetN S Protein of unknown function (DUF3900)
JOAHLMEO_00458 4.1e-226 exuT G Sugar (and other) transporter
JOAHLMEO_00459 4.1e-150 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JOAHLMEO_00460 2.6e-213 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
JOAHLMEO_00461 6.1e-188 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
JOAHLMEO_00462 2.1e-188 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
JOAHLMEO_00463 9.2e-248 yjmB G symporter YjmB
JOAHLMEO_00464 2.3e-278 uxaC 5.3.1.12 G glucuronate isomerase
JOAHLMEO_00465 2.9e-218 yjlD 1.6.99.3 C NADH dehydrogenase
JOAHLMEO_00466 7.1e-66 yjlC S Protein of unknown function (DUF1641)
JOAHLMEO_00467 4e-92 yjlB S Cupin domain
JOAHLMEO_00468 1.3e-134 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
JOAHLMEO_00469 9.5e-122 ybbM S transport system, permease component
JOAHLMEO_00470 4.9e-140 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
JOAHLMEO_00471 1.4e-29
JOAHLMEO_00472 6.5e-218 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
JOAHLMEO_00473 1.4e-223 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
JOAHLMEO_00475 2.5e-112 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
JOAHLMEO_00476 7.7e-10 S Domain of unknown function (DUF4352)
JOAHLMEO_00477 3.7e-94 yjgD S Protein of unknown function (DUF1641)
JOAHLMEO_00478 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
JOAHLMEO_00479 4.4e-103 yjgB S Domain of unknown function (DUF4309)
JOAHLMEO_00480 4.9e-34 T PhoQ Sensor
JOAHLMEO_00481 2.1e-168 yjfC O Predicted Zn-dependent protease (DUF2268)
JOAHLMEO_00482 2.3e-20 yjfB S Putative motility protein
JOAHLMEO_00483 1.8e-81 S Protein of unknown function (DUF2690)
JOAHLMEO_00484 1.1e-264 xynD 3.5.1.104 G Polysaccharide deacetylase
JOAHLMEO_00486 5.6e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
JOAHLMEO_00487 1e-51 yjdJ S Domain of unknown function (DUF4306)
JOAHLMEO_00488 7.1e-29 S Domain of unknown function (DUF4177)
JOAHLMEO_00489 1.1e-78 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JOAHLMEO_00491 2.1e-88 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
JOAHLMEO_00492 2.2e-48 yjdF S Protein of unknown function (DUF2992)
JOAHLMEO_00493 2.8e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
JOAHLMEO_00494 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
JOAHLMEO_00495 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
JOAHLMEO_00497 4.6e-140 IQ Enoyl-(Acyl carrier protein) reductase
JOAHLMEO_00498 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
JOAHLMEO_00499 3.4e-179 S response regulator aspartate phosphatase
JOAHLMEO_00501 7.4e-70 KLT Protein tyrosine kinase
JOAHLMEO_00502 1.9e-126 M nucleic acid phosphodiester bond hydrolysis
JOAHLMEO_00503 1.3e-48
JOAHLMEO_00505 9.5e-209 yjcL S Protein of unknown function (DUF819)
JOAHLMEO_00506 1.7e-96 rimJ 2.3.1.128 J Alanine acetyltransferase
JOAHLMEO_00507 6.5e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
JOAHLMEO_00508 1.5e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
JOAHLMEO_00509 1.5e-135 yjcH P COG2382 Enterochelin esterase and related enzymes
JOAHLMEO_00510 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
JOAHLMEO_00511 1.4e-69 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JOAHLMEO_00512 4.3e-48
JOAHLMEO_00513 2.4e-39 S LXG domain of WXG superfamily
JOAHLMEO_00514 1e-30
JOAHLMEO_00515 0.0 yjcD 3.6.4.12 L DNA helicase
JOAHLMEO_00516 2.9e-38 spoVIF S Stage VI sporulation protein F
JOAHLMEO_00519 1.3e-55 yjcA S Protein of unknown function (DUF1360)
JOAHLMEO_00520 2.3e-55 cotV S Spore Coat Protein X and V domain
JOAHLMEO_00521 8.5e-32 cotW
JOAHLMEO_00522 6.4e-77 cotX S Spore Coat Protein X and V domain
JOAHLMEO_00523 3.4e-96 cotY S Spore coat protein Z
JOAHLMEO_00524 5.2e-83 cotZ S Spore coat protein
JOAHLMEO_00525 5.9e-54 yjbX S Spore coat protein
JOAHLMEO_00526 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
JOAHLMEO_00527 6.9e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
JOAHLMEO_00528 1.9e-186 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
JOAHLMEO_00529 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
JOAHLMEO_00530 1.5e-29 thiS H thiamine diphosphate biosynthetic process
JOAHLMEO_00531 1.7e-215 thiO 1.4.3.19 E Glycine oxidase
JOAHLMEO_00532 1.6e-106 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
JOAHLMEO_00533 7.6e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JOAHLMEO_00534 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
JOAHLMEO_00535 2.5e-127 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
JOAHLMEO_00536 2.3e-159 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JOAHLMEO_00537 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JOAHLMEO_00538 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
JOAHLMEO_00539 7.1e-62 yjbL S Belongs to the UPF0738 family
JOAHLMEO_00540 1.2e-100 yjbK S protein conserved in bacteria
JOAHLMEO_00541 1.4e-88 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
JOAHLMEO_00542 3.7e-72 yjbI S Bacterial-like globin
JOAHLMEO_00543 1.2e-168 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
JOAHLMEO_00545 1.8e-20
JOAHLMEO_00546 0.0 pepF E oligoendopeptidase F
JOAHLMEO_00547 7.8e-08
JOAHLMEO_00550 4.8e-16 rsgI S Anti-sigma factor N-terminus
JOAHLMEO_00551 1.9e-26 sspD S small acid-soluble spore protein
JOAHLMEO_00552 5.6e-124 ykrK S Domain of unknown function (DUF1836)
JOAHLMEO_00553 3.5e-155 htpX O Belongs to the peptidase M48B family
JOAHLMEO_00554 2.2e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
JOAHLMEO_00555 1.2e-10 ydfR S Protein of unknown function (DUF421)
JOAHLMEO_00556 4.1e-18 ykzE
JOAHLMEO_00557 2.7e-188 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
JOAHLMEO_00558 0.0 kinE 2.7.13.3 T Histidine kinase
JOAHLMEO_00559 1.2e-88 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JOAHLMEO_00561 2.2e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JOAHLMEO_00562 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
JOAHLMEO_00563 8.6e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
JOAHLMEO_00564 3.1e-231 mtnE 2.6.1.83 E Aminotransferase
JOAHLMEO_00565 6.5e-229 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
JOAHLMEO_00566 8.3e-136 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
JOAHLMEO_00567 8e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
JOAHLMEO_00568 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
JOAHLMEO_00569 2.9e-51 XK27_09985 S Protein of unknown function (DUF1232)
JOAHLMEO_00570 7.5e-10 S Spo0E like sporulation regulatory protein
JOAHLMEO_00571 4.9e-62 eag
JOAHLMEO_00572 4.8e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
JOAHLMEO_00573 1.3e-75 ykvE K transcriptional
JOAHLMEO_00574 2.5e-125 motB N Flagellar motor protein
JOAHLMEO_00575 1e-137 motA N flagellar motor
JOAHLMEO_00576 0.0 clpE O Belongs to the ClpA ClpB family
JOAHLMEO_00577 3.3e-181 ykvI S membrane
JOAHLMEO_00578 2.1e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JOAHLMEO_00579 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
JOAHLMEO_00580 4.9e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
JOAHLMEO_00581 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JOAHLMEO_00582 3.8e-60 ykvN K HxlR-like helix-turn-helix
JOAHLMEO_00583 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
JOAHLMEO_00584 1.2e-213 ykvP 3.5.1.28 M Glycosyl transferases group 1
JOAHLMEO_00585 3.5e-35 3.5.1.104 M LysM domain
JOAHLMEO_00586 5.3e-162 G Glycosyl hydrolases family 18
JOAHLMEO_00587 5.6e-46 ykvR S Protein of unknown function (DUF3219)
JOAHLMEO_00588 6e-25 ykvS S protein conserved in bacteria
JOAHLMEO_00589 2.8e-28
JOAHLMEO_00590 3.1e-102 ykvT 3.5.1.28 M Cell Wall Hydrolase
JOAHLMEO_00591 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JOAHLMEO_00592 4.9e-90 stoA CO thiol-disulfide
JOAHLMEO_00593 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
JOAHLMEO_00594 2.3e-09
JOAHLMEO_00595 2.5e-208 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
JOAHLMEO_00596 4.9e-179 ykvZ 5.1.1.1 K Transcriptional regulator
JOAHLMEO_00598 7.6e-128 glcT K antiterminator
JOAHLMEO_00599 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JOAHLMEO_00600 2.1e-39 ptsH G phosphocarrier protein HPr
JOAHLMEO_00601 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JOAHLMEO_00602 7.2e-39 splA S Transcriptional regulator
JOAHLMEO_00603 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
JOAHLMEO_00604 2.7e-126 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JOAHLMEO_00605 1.3e-255 mcpC NT chemotaxis protein
JOAHLMEO_00606 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
JOAHLMEO_00607 4.6e-14 vgb H Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
JOAHLMEO_00608 1.8e-123 ykwD J protein with SCP PR1 domains
JOAHLMEO_00609 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
JOAHLMEO_00610 0.0 pilS 2.7.13.3 T Histidine kinase
JOAHLMEO_00611 6.3e-221 patA 2.6.1.1 E Aminotransferase
JOAHLMEO_00612 2.2e-15
JOAHLMEO_00613 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
JOAHLMEO_00614 4.9e-84 ykyB S YkyB-like protein
JOAHLMEO_00615 2.8e-238 ykuC EGP Major facilitator Superfamily
JOAHLMEO_00616 1.8e-87 ykuD S protein conserved in bacteria
JOAHLMEO_00617 4.7e-165 ykuE S Metallophosphoesterase
JOAHLMEO_00618 2.9e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JOAHLMEO_00619 5.2e-234 ykuI T Diguanylate phosphodiesterase
JOAHLMEO_00620 3.9e-37 ykuJ S protein conserved in bacteria
JOAHLMEO_00621 4.4e-94 ykuK S Ribonuclease H-like
JOAHLMEO_00622 3.9e-27 ykzF S Antirepressor AbbA
JOAHLMEO_00623 1.6e-76 ykuL S CBS domain
JOAHLMEO_00624 3.5e-168 ccpC K Transcriptional regulator
JOAHLMEO_00625 2.9e-84 fld C Flavodoxin domain
JOAHLMEO_00626 8.8e-175 ykuO
JOAHLMEO_00627 4.3e-77 fld C Flavodoxin
JOAHLMEO_00628 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
JOAHLMEO_00629 1.2e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
JOAHLMEO_00630 9e-37 ykuS S Belongs to the UPF0180 family
JOAHLMEO_00631 8.8e-142 ykuT M Mechanosensitive ion channel
JOAHLMEO_00632 3.9e-101 ykuU O Alkyl hydroperoxide reductase
JOAHLMEO_00633 1.4e-80 ykuV CO thiol-disulfide
JOAHLMEO_00634 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
JOAHLMEO_00635 1.1e-220 ylbJ S Sporulation integral membrane protein YlbJ
JOAHLMEO_00636 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JOAHLMEO_00637 1.2e-97 rsmD 2.1.1.171 L Methyltransferase
JOAHLMEO_00638 7.5e-39 ylbG S UPF0298 protein
JOAHLMEO_00639 1.8e-75 ylbF S Belongs to the UPF0342 family
JOAHLMEO_00640 1.5e-36 ylbE S YlbE-like protein
JOAHLMEO_00641 3.4e-62 ylbD S Putative coat protein
JOAHLMEO_00642 9.6e-200 ylbC S protein with SCP PR1 domains
JOAHLMEO_00643 2.6e-74 ylbB T COG0517 FOG CBS domain
JOAHLMEO_00644 2e-61 ylbA S YugN-like family
JOAHLMEO_00645 4.4e-166 ctaG S cytochrome c oxidase
JOAHLMEO_00646 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
JOAHLMEO_00647 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
JOAHLMEO_00648 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JOAHLMEO_00649 5.2e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
JOAHLMEO_00650 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
JOAHLMEO_00651 6.5e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
JOAHLMEO_00652 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JOAHLMEO_00653 7.2e-212 ftsW D Belongs to the SEDS family
JOAHLMEO_00654 8.7e-44 ylaN S Belongs to the UPF0358 family
JOAHLMEO_00655 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
JOAHLMEO_00656 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JOAHLMEO_00657 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
JOAHLMEO_00658 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
JOAHLMEO_00659 2.5e-32 ylaI S protein conserved in bacteria
JOAHLMEO_00660 4.2e-47 ylaH S YlaH-like protein
JOAHLMEO_00661 0.0 typA T GTP-binding protein TypA
JOAHLMEO_00662 8.2e-22 S Family of unknown function (DUF5325)
JOAHLMEO_00663 2.6e-37 ylaE
JOAHLMEO_00664 1.6e-11 sigC S Putative zinc-finger
JOAHLMEO_00665 1.5e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
JOAHLMEO_00666 3e-41 ylaB
JOAHLMEO_00667 0.0 ylaA
JOAHLMEO_00668 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
JOAHLMEO_00669 2.7e-171 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JOAHLMEO_00670 2e-77 ykzC S Acetyltransferase (GNAT) family
JOAHLMEO_00671 1.8e-150 suhB 3.1.3.25 G Inositol monophosphatase
JOAHLMEO_00672 7.1e-26 ykzI
JOAHLMEO_00673 1.3e-116 yktB S Belongs to the UPF0637 family
JOAHLMEO_00674 1.6e-42 yktA S Belongs to the UPF0223 family
JOAHLMEO_00675 7.7e-277 speA 4.1.1.19 E Arginine
JOAHLMEO_00676 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
JOAHLMEO_00677 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
JOAHLMEO_00678 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
JOAHLMEO_00679 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
JOAHLMEO_00680 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
JOAHLMEO_00681 2e-115 recN L Putative cell-wall binding lipoprotein
JOAHLMEO_00683 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
JOAHLMEO_00684 5.5e-147 ykrA S hydrolases of the HAD superfamily
JOAHLMEO_00685 8.2e-31 ykzG S Belongs to the UPF0356 family
JOAHLMEO_00686 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JOAHLMEO_00687 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JOAHLMEO_00688 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
JOAHLMEO_00689 1.6e-162 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
JOAHLMEO_00690 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
JOAHLMEO_00691 1.5e-43 abrB K of stationary sporulation gene expression
JOAHLMEO_00692 1.7e-182 mreB D Rod-share determining protein MreBH
JOAHLMEO_00693 1.1e-12 S Uncharacterized protein YkpC
JOAHLMEO_00694 1.3e-237 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
JOAHLMEO_00695 2.6e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JOAHLMEO_00696 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
JOAHLMEO_00697 8.1e-39 ykoA
JOAHLMEO_00698 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
JOAHLMEO_00699 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
JOAHLMEO_00700 5.3e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
JOAHLMEO_00701 3.1e-136 fruR K Transcriptional regulator
JOAHLMEO_00702 1.6e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
JOAHLMEO_00703 1e-122 macB V ABC transporter, ATP-binding protein
JOAHLMEO_00704 4.7e-157 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JOAHLMEO_00705 3.6e-115 yknW S Yip1 domain
JOAHLMEO_00706 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
JOAHLMEO_00707 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
JOAHLMEO_00708 8.3e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JOAHLMEO_00709 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
JOAHLMEO_00710 1.6e-91 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
JOAHLMEO_00711 1.9e-242 moeA 2.10.1.1 H molybdopterin
JOAHLMEO_00712 1.3e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
JOAHLMEO_00713 3.3e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
JOAHLMEO_00714 1.1e-40 yozN
JOAHLMEO_00715 1.9e-36 yocN
JOAHLMEO_00716 4.2e-56 yozO S Bacterial PH domain
JOAHLMEO_00717 2.7e-31 yozC
JOAHLMEO_00718 5.2e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
JOAHLMEO_00719 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
JOAHLMEO_00720 6e-165 sodA 1.15.1.1 P Superoxide dismutase
JOAHLMEO_00721 6.4e-230 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
JOAHLMEO_00722 1.9e-167 yocS S -transporter
JOAHLMEO_00723 1.6e-193 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
JOAHLMEO_00724 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
JOAHLMEO_00725 0.0 yojO P Von Willebrand factor
JOAHLMEO_00726 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
JOAHLMEO_00727 6.6e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JOAHLMEO_00728 1.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
JOAHLMEO_00729 1.8e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
JOAHLMEO_00730 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JOAHLMEO_00732 9.4e-245 norM V Multidrug efflux pump
JOAHLMEO_00733 4.2e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
JOAHLMEO_00734 2.1e-125 yojG S deacetylase
JOAHLMEO_00735 8.2e-60 yojF S Protein of unknown function (DUF1806)
JOAHLMEO_00736 1.5e-43
JOAHLMEO_00737 4.3e-161 rarD S -transporter
JOAHLMEO_00738 1.3e-60 yozR S COG0071 Molecular chaperone (small heat shock protein)
JOAHLMEO_00739 3.4e-09
JOAHLMEO_00740 1e-206 gntP EG COG2610 H gluconate symporter and related permeases
JOAHLMEO_00741 8e-64 yodA S tautomerase
JOAHLMEO_00742 7.4e-55 yodB K transcriptional
JOAHLMEO_00743 9.1e-107 yodC C nitroreductase
JOAHLMEO_00744 2.1e-111 mhqD S Carboxylesterase
JOAHLMEO_00745 7.9e-171 yodE E COG0346 Lactoylglutathione lyase and related lyases
JOAHLMEO_00746 6.2e-28 S Protein of unknown function (DUF3311)
JOAHLMEO_00747 1.2e-269 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JOAHLMEO_00748 9.7e-253 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
JOAHLMEO_00749 6.3e-128 yodH Q Methyltransferase
JOAHLMEO_00750 1.5e-23 yodI
JOAHLMEO_00751 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
JOAHLMEO_00752 4.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
JOAHLMEO_00753 5.3e-09
JOAHLMEO_00754 3.6e-54 yodL S YodL-like
JOAHLMEO_00755 2e-106 yodM 3.6.1.27 I Acid phosphatase homologues
JOAHLMEO_00756 2.8e-24 yozD S YozD-like protein
JOAHLMEO_00758 6e-123 yodN
JOAHLMEO_00759 1.4e-36 yozE S Belongs to the UPF0346 family
JOAHLMEO_00760 2.9e-47 yokU S YokU-like protein, putative antitoxin
JOAHLMEO_00761 3.9e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
JOAHLMEO_00762 2.3e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
JOAHLMEO_00763 4.6e-257 yodQ 3.5.1.16 E Acetylornithine deacetylase
JOAHLMEO_00764 2.3e-116 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
JOAHLMEO_00765 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JOAHLMEO_00766 1.5e-247 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JOAHLMEO_00768 4.1e-144 yiiD K acetyltransferase
JOAHLMEO_00769 4.7e-254 cgeD M maturation of the outermost layer of the spore
JOAHLMEO_00770 1e-37 cgeC
JOAHLMEO_00771 1.2e-65 cgeA
JOAHLMEO_00772 6.9e-186 cgeB S Spore maturation protein
JOAHLMEO_00773 8.3e-210 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
JOAHLMEO_00774 4.3e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
JOAHLMEO_00775 1.1e-77 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
JOAHLMEO_00776 1.3e-101 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JOAHLMEO_00777 1.6e-70 ypoP K transcriptional
JOAHLMEO_00778 1.7e-222 mepA V MATE efflux family protein
JOAHLMEO_00779 1.2e-28 ypmT S Uncharacterized ympT
JOAHLMEO_00780 1.1e-98 ypmS S protein conserved in bacteria
JOAHLMEO_00781 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
JOAHLMEO_00782 4.6e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
JOAHLMEO_00783 8.9e-40 ypmP S Protein of unknown function (DUF2535)
JOAHLMEO_00784 3.5e-241 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JOAHLMEO_00785 1.6e-110 K COG1802 Transcriptional regulators
JOAHLMEO_00786 2.7e-180 yjlA EG Putative multidrug resistance efflux transporter
JOAHLMEO_00788 7.5e-80 S Protein of unknown function with HXXEE motif
JOAHLMEO_00789 1.5e-97 ywrO S Flavodoxin-like fold
JOAHLMEO_00790 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JOAHLMEO_00791 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
JOAHLMEO_00792 4.1e-130 yqeB
JOAHLMEO_00793 1.2e-168 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
JOAHLMEO_00794 1.8e-105 yqeD S SNARE associated Golgi protein
JOAHLMEO_00795 4.1e-133 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
JOAHLMEO_00796 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
JOAHLMEO_00798 5.3e-95 yqeG S hydrolase of the HAD superfamily
JOAHLMEO_00799 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
JOAHLMEO_00800 2.3e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JOAHLMEO_00801 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
JOAHLMEO_00802 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JOAHLMEO_00803 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
JOAHLMEO_00804 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
JOAHLMEO_00805 1.1e-138 yqeM Q Methyltransferase
JOAHLMEO_00806 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JOAHLMEO_00807 2.1e-103 wza L COG1555 DNA uptake protein and related DNA-binding proteins
JOAHLMEO_00808 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
JOAHLMEO_00809 0.0 comEC S Competence protein ComEC
JOAHLMEO_00810 4.1e-15 S YqzM-like protein
JOAHLMEO_00811 2.8e-188 holA 2.7.7.7 L DNA polymerase III delta subunit
JOAHLMEO_00812 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
JOAHLMEO_00813 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
JOAHLMEO_00814 1.5e-222 spoIIP M stage II sporulation protein P
JOAHLMEO_00815 7.2e-53 yqxA S Protein of unknown function (DUF3679)
JOAHLMEO_00816 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
JOAHLMEO_00817 4.5e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
JOAHLMEO_00818 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
JOAHLMEO_00819 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JOAHLMEO_00820 0.0 dnaK O Heat shock 70 kDa protein
JOAHLMEO_00821 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
JOAHLMEO_00822 2.7e-174 prmA J Methylates ribosomal protein L11
JOAHLMEO_00823 1.8e-139 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
JOAHLMEO_00824 1e-259 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
JOAHLMEO_00825 5.1e-154 yqeW P COG1283 Na phosphate symporter
JOAHLMEO_00826 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
JOAHLMEO_00827 2.5e-61 yqeY S Yqey-like protein
JOAHLMEO_00828 4.5e-228 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
JOAHLMEO_00829 3.7e-121 yqfA S UPF0365 protein
JOAHLMEO_00830 1.3e-24 yqfB
JOAHLMEO_00831 2.7e-45 yqfC S sporulation protein YqfC
JOAHLMEO_00832 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
JOAHLMEO_00833 4.2e-175 phoH T Phosphate starvation-inducible protein PhoH
JOAHLMEO_00835 0.0 yqfF S membrane-associated HD superfamily hydrolase
JOAHLMEO_00836 6.7e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JOAHLMEO_00837 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
JOAHLMEO_00838 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
JOAHLMEO_00839 8.4e-165 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JOAHLMEO_00840 8.4e-19 S YqzL-like protein
JOAHLMEO_00841 6.9e-144 recO L Involved in DNA repair and RecF pathway recombination
JOAHLMEO_00842 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
JOAHLMEO_00843 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
JOAHLMEO_00844 4.5e-112 ccpN K CBS domain
JOAHLMEO_00845 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
JOAHLMEO_00846 4.5e-88 yaiI S Belongs to the UPF0178 family
JOAHLMEO_00847 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
JOAHLMEO_00848 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
JOAHLMEO_00849 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
JOAHLMEO_00850 1.5e-115 trmK 2.1.1.217 S SAM-dependent methyltransferase
JOAHLMEO_00851 1.9e-211 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JOAHLMEO_00852 1.6e-38 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JOAHLMEO_00853 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
JOAHLMEO_00854 7e-138 srfAD Q thioesterase
JOAHLMEO_00855 3.7e-224 EGP Major Facilitator Superfamily
JOAHLMEO_00856 1.2e-84 S YcxB-like protein
JOAHLMEO_00857 9.3e-159 ycxC EG EamA-like transporter family
JOAHLMEO_00858 6.2e-249 ycxD K GntR family transcriptional regulator
JOAHLMEO_00859 4.7e-112 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
JOAHLMEO_00860 9.7e-115 yczE S membrane
JOAHLMEO_00861 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
JOAHLMEO_00862 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
JOAHLMEO_00863 1.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
JOAHLMEO_00864 1.9e-161 bsdA K LysR substrate binding domain
JOAHLMEO_00865 3.7e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
JOAHLMEO_00866 4.5e-282 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
JOAHLMEO_00867 8.9e-39 bsdD 4.1.1.61 S response to toxic substance
JOAHLMEO_00868 2.5e-80 yclD
JOAHLMEO_00869 7.8e-157 yclE 3.4.11.5 S Alpha beta hydrolase
JOAHLMEO_00870 2.3e-265 dtpT E amino acid peptide transporter
JOAHLMEO_00871 2.7e-300 yclG M Pectate lyase superfamily protein
JOAHLMEO_00873 2.4e-279 gerKA EG Spore germination protein
JOAHLMEO_00874 6.3e-232 gerKC S spore germination
JOAHLMEO_00875 3.8e-199 gerKB F Spore germination protein
JOAHLMEO_00876 7.3e-121 yclH P ABC transporter
JOAHLMEO_00877 6.2e-202 yclI V ABC transporter (permease) YclI
JOAHLMEO_00878 6.8e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JOAHLMEO_00879 3.1e-259 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
JOAHLMEO_00880 1.3e-77 S aspartate phosphatase
JOAHLMEO_00884 2.6e-250 lysC 2.7.2.4 E Belongs to the aspartokinase family
JOAHLMEO_00885 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOAHLMEO_00886 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOAHLMEO_00887 1.3e-134 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
JOAHLMEO_00888 9.4e-167 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
JOAHLMEO_00889 1.2e-250 ycnB EGP Major facilitator Superfamily
JOAHLMEO_00890 6.5e-154 ycnC K Transcriptional regulator
JOAHLMEO_00891 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
JOAHLMEO_00892 1.6e-45 ycnE S Monooxygenase
JOAHLMEO_00893 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
JOAHLMEO_00894 7.3e-272 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JOAHLMEO_00895 4.8e-246 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JOAHLMEO_00896 1.3e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
JOAHLMEO_00897 6.1e-149 glcU U Glucose uptake
JOAHLMEO_00898 6e-143 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JOAHLMEO_00899 1.4e-99 ycnI S protein conserved in bacteria
JOAHLMEO_00900 5.5e-308 ycnJ P protein, homolog of Cu resistance protein CopC
JOAHLMEO_00901 7.3e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
JOAHLMEO_00902 3.4e-53
JOAHLMEO_00903 7.4e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
JOAHLMEO_00904 5.7e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
JOAHLMEO_00905 1.5e-208 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
JOAHLMEO_00906 4.2e-200 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
JOAHLMEO_00908 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
JOAHLMEO_00909 7e-107 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
JOAHLMEO_00910 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
JOAHLMEO_00912 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
JOAHLMEO_00913 1.7e-13 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
JOAHLMEO_00914 4.4e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
JOAHLMEO_00915 1.3e-134 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
JOAHLMEO_00916 5.9e-288 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
JOAHLMEO_00917 3.6e-232 nrnB S phosphohydrolase (DHH superfamily)
JOAHLMEO_00918 5.5e-104 yngC S membrane-associated protein
JOAHLMEO_00919 5.9e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
JOAHLMEO_00920 8.5e-78 yngA S membrane
JOAHLMEO_00921 1.7e-295 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
JOAHLMEO_00922 4.2e-247 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
JOAHLMEO_00924 4.9e-295 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
JOAHLMEO_00925 1.2e-250 agcS E Sodium alanine symporter
JOAHLMEO_00926 1.3e-57 ynfC
JOAHLMEO_00927 2.3e-12
JOAHLMEO_00928 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JOAHLMEO_00929 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JOAHLMEO_00930 6.6e-69 yccU S CoA-binding protein
JOAHLMEO_00931 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
JOAHLMEO_00932 4.1e-49 yneR S Belongs to the HesB IscA family
JOAHLMEO_00933 1.3e-53 yneQ
JOAHLMEO_00934 1.2e-73 yneP S Thioesterase-like superfamily
JOAHLMEO_00935 3.9e-35 tlp S Belongs to the Tlp family
JOAHLMEO_00936 3.1e-08 sspN S Small acid-soluble spore protein N family
JOAHLMEO_00938 2.9e-90 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JOAHLMEO_00939 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JOAHLMEO_00940 2.2e-14 sspO S Belongs to the SspO family
JOAHLMEO_00941 3.9e-19 sspP S Belongs to the SspP family
JOAHLMEO_00942 5.9e-64 hspX O Spore coat protein
JOAHLMEO_00943 4.2e-74 yneK S Protein of unknown function (DUF2621)
JOAHLMEO_00944 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
JOAHLMEO_00945 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
JOAHLMEO_00946 6e-126 ccdA O cytochrome c biogenesis protein
JOAHLMEO_00947 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
JOAHLMEO_00948 1.8e-28 yneF S UPF0154 protein
JOAHLMEO_00949 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
JOAHLMEO_00950 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JOAHLMEO_00951 4.8e-32 ynzC S UPF0291 protein
JOAHLMEO_00952 2.1e-109 yneB L resolvase
JOAHLMEO_00953 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
JOAHLMEO_00954 9.9e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JOAHLMEO_00955 5.8e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
JOAHLMEO_00956 5.8e-74 yndM S Protein of unknown function (DUF2512)
JOAHLMEO_00957 3.6e-137 yndL S Replication protein
JOAHLMEO_00959 3e-306 yndJ S YndJ-like protein
JOAHLMEO_00960 7.1e-115 yndH S Domain of unknown function (DUF4166)
JOAHLMEO_00961 1.7e-148 yndG S DoxX-like family
JOAHLMEO_00962 1.4e-215 gerLC S Spore germination protein
JOAHLMEO_00963 1.2e-194 gerAB U Spore germination
JOAHLMEO_00964 4.5e-283 gerAA EG Spore germination protein
JOAHLMEO_00967 1.5e-79 yndB S Activator of Hsp90 ATPase homolog 1-like protein
JOAHLMEO_00968 5.3e-71
JOAHLMEO_00969 7.9e-25 tatA U protein secretion
JOAHLMEO_00972 1.2e-127 S Domain of unknown function, YrpD
JOAHLMEO_00973 8.6e-164 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JOAHLMEO_00976 5.2e-15
JOAHLMEO_00977 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
JOAHLMEO_00978 5e-81 yncE S Protein of unknown function (DUF2691)
JOAHLMEO_00980 3.8e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JOAHLMEO_00981 4.7e-255 iolT EGP Major facilitator Superfamily
JOAHLMEO_00982 1.2e-112 yokF 3.1.31.1 L RNA catabolic process
JOAHLMEO_00983 1.8e-289 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
JOAHLMEO_00984 1.6e-260 xylA 5.3.1.5 G Belongs to the xylose isomerase family
JOAHLMEO_00985 2.3e-212 xylR GK ROK family
JOAHLMEO_00986 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
JOAHLMEO_00987 2.3e-254 xynT G MFS/sugar transport protein
JOAHLMEO_00988 5.5e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
JOAHLMEO_00991 3.1e-121 ynaE S Domain of unknown function (DUF3885)
JOAHLMEO_00992 2.5e-97 ynaD J Acetyltransferase (GNAT) domain
JOAHLMEO_00993 8.3e-12 S Protein of unknown function (DUF1433)
JOAHLMEO_00994 9.6e-141 ynaC
JOAHLMEO_00995 8.9e-90 G SMI1-KNR4 cell-wall
JOAHLMEO_00996 3.2e-37
JOAHLMEO_00997 4.6e-31
JOAHLMEO_00998 3.8e-10
JOAHLMEO_01001 4.2e-17 S Terminase
JOAHLMEO_01002 1.7e-77 L phage terminase small subunit
JOAHLMEO_01006 3e-08 KLT serine threonine protein kinase
JOAHLMEO_01007 7.5e-59
JOAHLMEO_01009 1.5e-15
JOAHLMEO_01010 1.1e-64
JOAHLMEO_01011 7e-261 glnA 6.3.1.2 E glutamine synthetase
JOAHLMEO_01012 1.1e-68 glnR K transcriptional
JOAHLMEO_01013 3.7e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
JOAHLMEO_01014 5.1e-229 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JOAHLMEO_01015 1.7e-176 spoVK O stage V sporulation protein K
JOAHLMEO_01016 1.4e-115 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
JOAHLMEO_01017 2e-109 ymaB
JOAHLMEO_01018 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JOAHLMEO_01019 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JOAHLMEO_01020 7.4e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
JOAHLMEO_01021 4.5e-22 ymzA
JOAHLMEO_01022 9.7e-16
JOAHLMEO_01023 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
JOAHLMEO_01024 1.3e-173 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JOAHLMEO_01025 1e-45 ymaF S YmaF family
JOAHLMEO_01027 5.4e-50 ebrA P Small Multidrug Resistance protein
JOAHLMEO_01028 1.4e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
JOAHLMEO_01029 1.3e-78 ymaD O redox protein, regulator of disulfide bond formation
JOAHLMEO_01030 2.1e-126 ymaC S Replication protein
JOAHLMEO_01031 1.9e-07 K Transcriptional regulator
JOAHLMEO_01032 5e-251 aprX O Belongs to the peptidase S8 family
JOAHLMEO_01033 6.2e-162 ymaE S Metallo-beta-lactamase superfamily
JOAHLMEO_01034 2e-61 ymzB
JOAHLMEO_01035 1.8e-231 cypA C Cytochrome P450
JOAHLMEO_01036 0.0 pks13 HQ Beta-ketoacyl synthase
JOAHLMEO_01037 0.0 dhbF IQ polyketide synthase
JOAHLMEO_01038 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
JOAHLMEO_01039 0.0 pfaA Q Polyketide synthase of type I
JOAHLMEO_01040 0.0 rhiB IQ polyketide synthase
JOAHLMEO_01041 6.1e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
JOAHLMEO_01042 2.7e-140 pksH 4.2.1.18 I enoyl-CoA hydratase
JOAHLMEO_01043 1.5e-244 pksG 2.3.3.10 I synthase
JOAHLMEO_01044 2.8e-235 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
JOAHLMEO_01045 1.4e-37 acpK IQ Phosphopantetheine attachment site
JOAHLMEO_01046 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
JOAHLMEO_01047 6.6e-184 pksD Q Acyl transferase domain
JOAHLMEO_01048 2.2e-162 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
JOAHLMEO_01049 4.7e-128 pksB 3.1.2.6 S Polyketide biosynthesis
JOAHLMEO_01050 2.2e-108 pksA K Transcriptional regulator
JOAHLMEO_01051 5.1e-96 ymcC S Membrane
JOAHLMEO_01053 4.1e-67 S Regulatory protein YrvL
JOAHLMEO_01054 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JOAHLMEO_01055 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JOAHLMEO_01056 2.2e-88 cotE S Spore coat protein
JOAHLMEO_01057 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
JOAHLMEO_01058 5e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JOAHLMEO_01059 7.2e-217 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
JOAHLMEO_01060 3.3e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
JOAHLMEO_01061 1.2e-36 spoVS S Stage V sporulation protein S
JOAHLMEO_01062 1.9e-152 ymdB S protein conserved in bacteria
JOAHLMEO_01063 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
JOAHLMEO_01064 8.8e-215 pbpX V Beta-lactamase
JOAHLMEO_01065 2e-116 ywqC M biosynthesis protein
JOAHLMEO_01066 1.2e-17
JOAHLMEO_01067 7.8e-307 ywqB S SWIM zinc finger
JOAHLMEO_01068 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
JOAHLMEO_01069 1.5e-155 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
JOAHLMEO_01070 5.7e-138 glcR K COG1349 Transcriptional regulators of sugar metabolism
JOAHLMEO_01071 4.9e-57 ssbB L Single-stranded DNA-binding protein
JOAHLMEO_01072 3.8e-66 ywpG
JOAHLMEO_01073 4e-66 ywpF S YwpF-like protein
JOAHLMEO_01074 3e-84 srtA 3.4.22.70 M Sortase family
JOAHLMEO_01075 0.0 M1-568 M cell wall anchor domain
JOAHLMEO_01076 2.6e-173 M1-574 T Transcriptional regulatory protein, C terminal
JOAHLMEO_01077 0.0 ywpD T PhoQ Sensor
JOAHLMEO_01078 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
JOAHLMEO_01079 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
JOAHLMEO_01080 7.5e-197 S aspartate phosphatase
JOAHLMEO_01081 1.1e-139 flhP N flagellar basal body
JOAHLMEO_01082 1.7e-124 flhO N flagellar basal body
JOAHLMEO_01083 3.5e-180 mbl D Rod shape-determining protein
JOAHLMEO_01084 3e-44 spoIIID K Stage III sporulation protein D
JOAHLMEO_01085 2.1e-70 ywoH K COG1846 Transcriptional regulators
JOAHLMEO_01086 1.1e-209 ywoG EGP Major facilitator Superfamily
JOAHLMEO_01088 1.3e-225 ywoF P Right handed beta helix region
JOAHLMEO_01089 7.5e-280 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
JOAHLMEO_01090 9.1e-240 ywoD EGP Major facilitator superfamily
JOAHLMEO_01091 6.8e-104 phzA Q Isochorismatase family
JOAHLMEO_01092 5.7e-77
JOAHLMEO_01093 3.3e-225 amt P Ammonium transporter
JOAHLMEO_01094 1.6e-58 nrgB K Belongs to the P(II) protein family
JOAHLMEO_01095 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
JOAHLMEO_01096 7.8e-73 ywnJ S VanZ like family
JOAHLMEO_01097 2.6e-115 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
JOAHLMEO_01098 2.7e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
JOAHLMEO_01099 9.5e-12 ywnC S Family of unknown function (DUF5362)
JOAHLMEO_01100 2.9e-70 ywnF S Family of unknown function (DUF5392)
JOAHLMEO_01101 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JOAHLMEO_01102 2.6e-143 mta K transcriptional
JOAHLMEO_01103 1.7e-58 ywnC S Family of unknown function (DUF5362)
JOAHLMEO_01104 5.3e-113 ywnB S NAD(P)H-binding
JOAHLMEO_01105 1.7e-64 ywnA K Transcriptional regulator
JOAHLMEO_01106 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
JOAHLMEO_01107 6.5e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
JOAHLMEO_01108 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
JOAHLMEO_01109 3.8e-11 csbD K CsbD-like
JOAHLMEO_01110 3e-84 ywmF S Peptidase M50
JOAHLMEO_01111 7.9e-104 S response regulator aspartate phosphatase
JOAHLMEO_01112 1.1e-189 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JOAHLMEO_01113 9.9e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JOAHLMEO_01115 2.1e-120 ywmD S protein containing a von Willebrand factor type A (vWA) domain
JOAHLMEO_01116 1.9e-121 ywmC S protein containing a von Willebrand factor type A (vWA) domain
JOAHLMEO_01117 3.5e-175 spoIID D Stage II sporulation protein D
JOAHLMEO_01118 6.1e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JOAHLMEO_01120 6.7e-41 ytzC S Protein of unknown function (DUF2524)
JOAHLMEO_01121 3.1e-189 yhcC S Fe-S oxidoreductase
JOAHLMEO_01122 9.7e-106 ytqB J Putative rRNA methylase
JOAHLMEO_01123 2.8e-215 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
JOAHLMEO_01124 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
JOAHLMEO_01125 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JOAHLMEO_01126 2.4e-256 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
JOAHLMEO_01127 0.0 asnB 6.3.5.4 E Asparagine synthase
JOAHLMEO_01128 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JOAHLMEO_01129 8.8e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JOAHLMEO_01130 1.2e-38 ytmB S Protein of unknown function (DUF2584)
JOAHLMEO_01131 5.2e-147 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
JOAHLMEO_01132 8e-188 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
JOAHLMEO_01133 1.4e-144 ytlC P ABC transporter
JOAHLMEO_01134 6.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
JOAHLMEO_01135 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
JOAHLMEO_01136 7.8e-62 ytkC S Bacteriophage holin family
JOAHLMEO_01137 2.1e-76 dps P Belongs to the Dps family
JOAHLMEO_01139 2.4e-72 ytkA S YtkA-like
JOAHLMEO_01140 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
JOAHLMEO_01141 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
JOAHLMEO_01142 6.1e-41 rpmE2 J Ribosomal protein L31
JOAHLMEO_01143 4e-248 cydA 1.10.3.14 C oxidase, subunit
JOAHLMEO_01144 3.6e-188 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
JOAHLMEO_01145 1.1e-24 S Domain of Unknown Function (DUF1540)
JOAHLMEO_01146 2.6e-150 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
JOAHLMEO_01147 4.4e-231 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
JOAHLMEO_01148 6.1e-137 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
JOAHLMEO_01149 3.9e-170 troA P Belongs to the bacterial solute-binding protein 9 family
JOAHLMEO_01150 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
JOAHLMEO_01151 6.7e-273 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
JOAHLMEO_01152 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JOAHLMEO_01153 1.4e-153 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
JOAHLMEO_01154 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JOAHLMEO_01155 1.6e-271 menF 5.4.4.2 HQ Isochorismate synthase
JOAHLMEO_01156 2.6e-132 dksA T COG1734 DnaK suppressor protein
JOAHLMEO_01157 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
JOAHLMEO_01158 3.7e-243 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JOAHLMEO_01159 6.9e-178 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
JOAHLMEO_01160 1e-234 ytcC M Glycosyltransferase Family 4
JOAHLMEO_01162 2.5e-205 cotS S Seems to be required for the assembly of the CotSA protein in spores
JOAHLMEO_01163 1.8e-217 cotSA M Glycosyl transferases group 1
JOAHLMEO_01164 3.7e-204 cotI S Spore coat protein
JOAHLMEO_01165 4.9e-76 tspO T membrane
JOAHLMEO_01166 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
JOAHLMEO_01167 7.6e-285 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
JOAHLMEO_01168 4.9e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
JOAHLMEO_01169 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JOAHLMEO_01170 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JOAHLMEO_01178 1.8e-33
JOAHLMEO_01179 1e-144 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
JOAHLMEO_01180 1.6e-36 crh G Phosphocarrier protein Chr
JOAHLMEO_01181 1.4e-170 whiA K May be required for sporulation
JOAHLMEO_01182 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
JOAHLMEO_01183 5.7e-166 rapZ S Displays ATPase and GTPase activities
JOAHLMEO_01184 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
JOAHLMEO_01185 1.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
JOAHLMEO_01186 4.3e-99 usp CBM50 M protein conserved in bacteria
JOAHLMEO_01187 7.6e-277 S COG0457 FOG TPR repeat
JOAHLMEO_01188 0.0 msbA2 3.6.3.44 V ABC transporter
JOAHLMEO_01190 2.9e-252
JOAHLMEO_01191 1.1e-77
JOAHLMEO_01192 9.8e-112 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
JOAHLMEO_01193 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
JOAHLMEO_01194 3.8e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JOAHLMEO_01195 4.4e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JOAHLMEO_01196 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
JOAHLMEO_01197 8.4e-227 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JOAHLMEO_01198 4.8e-114 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
JOAHLMEO_01199 2.9e-218 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JOAHLMEO_01200 4.5e-140 yvpB NU protein conserved in bacteria
JOAHLMEO_01201 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
JOAHLMEO_01202 8.7e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
JOAHLMEO_01203 1.9e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
JOAHLMEO_01204 1.1e-159 yvoD P COG0370 Fe2 transport system protein B
JOAHLMEO_01205 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JOAHLMEO_01206 4.9e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JOAHLMEO_01207 8.3e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
JOAHLMEO_01208 9.8e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
JOAHLMEO_01209 3.6e-134 yvoA K transcriptional
JOAHLMEO_01210 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
JOAHLMEO_01211 1.2e-50 yvlD S Membrane
JOAHLMEO_01212 2.6e-26 pspB KT PspC domain
JOAHLMEO_01213 9.2e-166 yvlB S Putative adhesin
JOAHLMEO_01214 8e-49 yvlA
JOAHLMEO_01215 5.7e-33 yvkN
JOAHLMEO_01216 1.2e-114 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JOAHLMEO_01217 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
JOAHLMEO_01218 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
JOAHLMEO_01219 1.2e-30 csbA S protein conserved in bacteria
JOAHLMEO_01220 0.0 yvkC 2.7.9.2 GT Phosphotransferase
JOAHLMEO_01221 1e-99 yvkB K Transcriptional regulator
JOAHLMEO_01222 2.8e-225 yvkA EGP Major facilitator Superfamily
JOAHLMEO_01223 3.2e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JOAHLMEO_01224 5.3e-56 swrA S Swarming motility protein
JOAHLMEO_01225 5.8e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
JOAHLMEO_01226 5.3e-66 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
JOAHLMEO_01227 1e-113 hpr K Negative regulator of protease production and sporulation
JOAHLMEO_01228 1.3e-54 yhaI S Protein of unknown function (DUF1878)
JOAHLMEO_01229 8.7e-90 yhaK S Putative zincin peptidase
JOAHLMEO_01230 1e-119 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
JOAHLMEO_01231 1.6e-21 yhaL S Sporulation protein YhaL
JOAHLMEO_01232 5.8e-177 yhaM L Shows a 3'-5' exoribonuclease activity
JOAHLMEO_01233 0.0 yhaN L AAA domain
JOAHLMEO_01234 1.8e-223 yhaO L DNA repair exonuclease
JOAHLMEO_01235 1.2e-214 yhaP CP COG1668 ABC-type Na efflux pump, permease component
JOAHLMEO_01236 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
JOAHLMEO_01237 2.4e-26 S YhzD-like protein
JOAHLMEO_01238 5.5e-131 yhaR 5.3.3.18 I enoyl-CoA hydratase
JOAHLMEO_01240 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
JOAHLMEO_01241 1.1e-207 yhaU P COG0475 Kef-type K transport systems, membrane components
JOAHLMEO_01242 1.9e-291 hemZ H coproporphyrinogen III oxidase
JOAHLMEO_01243 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
JOAHLMEO_01244 2.2e-204 yhaZ L DNA alkylation repair enzyme
JOAHLMEO_01245 9.5e-48 yheA S Belongs to the UPF0342 family
JOAHLMEO_01246 2.2e-202 yheB S Belongs to the UPF0754 family
JOAHLMEO_01247 4.3e-216 yheC HJ YheC/D like ATP-grasp
JOAHLMEO_01248 3.3e-266 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
JOAHLMEO_01249 1.3e-36 yheE S Family of unknown function (DUF5342)
JOAHLMEO_01250 6.3e-28 sspB S spore protein
JOAHLMEO_01251 1.5e-109 yheG GM NAD(P)H-binding
JOAHLMEO_01252 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
JOAHLMEO_01253 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
JOAHLMEO_01254 1.7e-83 nhaX T Belongs to the universal stress protein A family
JOAHLMEO_01255 1.3e-230 nhaC C Na H antiporter
JOAHLMEO_01256 9e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
JOAHLMEO_01257 2.1e-146 yheN G deacetylase
JOAHLMEO_01258 5e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
JOAHLMEO_01259 5.2e-201 yhdY M Mechanosensitive ion channel
JOAHLMEO_01261 2.3e-133 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
JOAHLMEO_01262 4.3e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JOAHLMEO_01263 1.7e-44 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JOAHLMEO_01264 3.3e-245 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
JOAHLMEO_01265 2.8e-221 yhdR 2.6.1.1 E Aminotransferase
JOAHLMEO_01266 4.7e-74 cueR K transcriptional
JOAHLMEO_01267 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
JOAHLMEO_01268 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
JOAHLMEO_01269 4.4e-191 yhdN C Aldo keto reductase
JOAHLMEO_01270 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
JOAHLMEO_01271 6.6e-201 yhdL S Sigma factor regulator N-terminal
JOAHLMEO_01272 8.1e-45 yhdK S Sigma-M inhibitor protein
JOAHLMEO_01273 2.6e-76 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JOAHLMEO_01274 2.4e-267 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JOAHLMEO_01275 1.5e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
JOAHLMEO_01276 3.4e-250 yhdG E amino acid
JOAHLMEO_01277 1.3e-110 yrkJ S membrane transporter protein
JOAHLMEO_01278 1.6e-35 yrkI O Belongs to the sulfur carrier protein TusA family
JOAHLMEO_01279 1.1e-203 yrkH P Rhodanese Homology Domain
JOAHLMEO_01280 2.2e-29 perX S DsrE/DsrF-like family
JOAHLMEO_01281 1.4e-98 yrkF OP Belongs to the sulfur carrier protein TusA family
JOAHLMEO_01282 4e-46 P Rhodanese Homology Domain
JOAHLMEO_01283 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
JOAHLMEO_01284 7.8e-39 yrkD S protein conserved in bacteria
JOAHLMEO_01285 5e-21
JOAHLMEO_01286 8.4e-107 yrkC G Cupin domain
JOAHLMEO_01288 1.1e-147 bltR K helix_turn_helix, mercury resistance
JOAHLMEO_01289 3e-210 blt EGP Major facilitator Superfamily
JOAHLMEO_01290 4.5e-82 bltD 2.3.1.57 K FR47-like protein
JOAHLMEO_01291 5.1e-232 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
JOAHLMEO_01292 3.9e-16 S YrzO-like protein
JOAHLMEO_01293 3.3e-164 yrdR EG EamA-like transporter family
JOAHLMEO_01294 1.9e-158 yrdQ K Transcriptional regulator
JOAHLMEO_01295 7.3e-197 trkA P Oxidoreductase
JOAHLMEO_01296 6.5e-144 czcD P COG1230 Co Zn Cd efflux system component
JOAHLMEO_01297 2.5e-65 yodA S tautomerase
JOAHLMEO_01298 1.5e-161 gltR K LysR substrate binding domain
JOAHLMEO_01299 3.2e-229 brnQ E Component of the transport system for branched-chain amino acids
JOAHLMEO_01300 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
JOAHLMEO_01301 3.3e-138 azlC E AzlC protein
JOAHLMEO_01302 6.3e-79 bkdR K helix_turn_helix ASNC type
JOAHLMEO_01303 1.9e-40 yrdF K ribonuclease inhibitor
JOAHLMEO_01304 1.3e-221 cypA C Cytochrome P450
JOAHLMEO_01305 1.2e-25 K Acetyltransferase (GNAT) family
JOAHLMEO_01307 6.7e-64 K Transcriptional regulator
JOAHLMEO_01308 4.9e-163 scrR K transcriptional
JOAHLMEO_01309 2.6e-228 msmE G Bacterial extracellular solute-binding protein
JOAHLMEO_01310 3.9e-149 msmF P Binding-protein-dependent transport system inner membrane component
JOAHLMEO_01311 1.1e-139 msmG P PFAM binding-protein-dependent transport systems inner membrane component
JOAHLMEO_01312 2.1e-198 rafB P LacY proton/sugar symporter
JOAHLMEO_01313 1.1e-251 cscA 3.2.1.26 GH32 G invertase
JOAHLMEO_01314 6.5e-130 2.7.1.4 G Belongs to the carbohydrate kinase PfkB family
JOAHLMEO_01315 7.2e-74 maa 2.3.1.79 S COG0110 Acetyltransferase (isoleucine patch superfamily)
JOAHLMEO_01316 4.5e-100 yrdC 3.5.1.19 Q Isochorismatase family
JOAHLMEO_01317 4e-55 S Protein of unknown function (DUF2568)
JOAHLMEO_01319 3.2e-89 yrdA S DinB family
JOAHLMEO_01320 5e-167 aadK G Streptomycin adenylyltransferase
JOAHLMEO_01321 4.2e-192 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
JOAHLMEO_01322 3.8e-145 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
JOAHLMEO_01323 1.6e-123 yrpD S Domain of unknown function, YrpD
JOAHLMEO_01324 1.9e-98 flr S Flavin reductase like domain
JOAHLMEO_01325 7.2e-118 bmrR K helix_turn_helix, mercury resistance
JOAHLMEO_01326 2.8e-49 yjbR S YjbR
JOAHLMEO_01327 1.1e-112 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
JOAHLMEO_01328 5.9e-94 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
JOAHLMEO_01329 1.7e-187 yrpG C Aldo/keto reductase family
JOAHLMEO_01330 2.1e-154 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
JOAHLMEO_01331 3.2e-68 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JOAHLMEO_01332 2.1e-76 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JOAHLMEO_01333 1.2e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
JOAHLMEO_01334 3.8e-162 citR K Transcriptional regulator
JOAHLMEO_01335 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
JOAHLMEO_01336 4.7e-252 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
JOAHLMEO_01337 2.1e-276 ycgB S Stage V sporulation protein R
JOAHLMEO_01338 3.1e-236 ygxB M Conserved TM helix
JOAHLMEO_01339 1e-75 nsrR K Transcriptional regulator
JOAHLMEO_01340 2.5e-187 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
JOAHLMEO_01341 1.8e-53 yhdC S Protein of unknown function (DUF3889)
JOAHLMEO_01342 1.2e-38 yhdB S YhdB-like protein
JOAHLMEO_01343 3.6e-83 azr 1.7.1.6 S NADPH-dependent FMN reductase
JOAHLMEO_01344 3.2e-110 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JOAHLMEO_01345 2.7e-213 yhcY 2.7.13.3 T Histidine kinase
JOAHLMEO_01346 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
JOAHLMEO_01347 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JOAHLMEO_01348 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JOAHLMEO_01349 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
JOAHLMEO_01350 1.2e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
JOAHLMEO_01351 6e-260 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JOAHLMEO_01352 4.6e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
JOAHLMEO_01353 4.6e-120 yhcW 5.4.2.6 S hydrolase
JOAHLMEO_01354 9.9e-68 yhcV S COG0517 FOG CBS domain
JOAHLMEO_01355 2.1e-67 yhcU S Family of unknown function (DUF5365)
JOAHLMEO_01356 3.3e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JOAHLMEO_01357 5.4e-104 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
JOAHLMEO_01358 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
JOAHLMEO_01359 5.2e-100 yhcQ M Spore coat protein
JOAHLMEO_01360 2.5e-167 yhcP
JOAHLMEO_01361 6e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
JOAHLMEO_01362 1.1e-40 yhcM
JOAHLMEO_01363 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
JOAHLMEO_01364 2.9e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
JOAHLMEO_01365 3.1e-150 metQ M Belongs to the nlpA lipoprotein family
JOAHLMEO_01366 1e-30 cspB K Cold-shock protein
JOAHLMEO_01367 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
JOAHLMEO_01368 7.7e-166 yhcH V ABC transporter, ATP-binding protein
JOAHLMEO_01369 4e-122 yhcG V ABC transporter, ATP-binding protein
JOAHLMEO_01370 1.9e-59 yhcF K Transcriptional regulator
JOAHLMEO_01371 1.3e-54
JOAHLMEO_01372 2.8e-37 yhcC
JOAHLMEO_01373 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
JOAHLMEO_01374 3.1e-271 yhcA EGP Major facilitator Superfamily
JOAHLMEO_01375 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
JOAHLMEO_01376 2.2e-76 yhbI K DNA-binding transcription factor activity
JOAHLMEO_01377 2.5e-225 yhbH S Belongs to the UPF0229 family
JOAHLMEO_01378 1.6e-55 prkA T Ser protein kinase
JOAHLMEO_01380 1.3e-270 C Fe-S oxidoreductases
JOAHLMEO_01381 1e-07 S Bacteriocin subtilosin A
JOAHLMEO_01382 4.7e-73 ywiB S protein conserved in bacteria
JOAHLMEO_01383 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
JOAHLMEO_01384 1.3e-213 narK P COG2223 Nitrate nitrite transporter
JOAHLMEO_01385 2.6e-129 fnr K helix_turn_helix, cAMP Regulatory protein
JOAHLMEO_01386 1.7e-139 ywiC S YwiC-like protein
JOAHLMEO_01387 4.5e-85 arfM T cyclic nucleotide binding
JOAHLMEO_01388 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JOAHLMEO_01389 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
JOAHLMEO_01390 2.1e-94 narJ 1.7.5.1 C nitrate reductase
JOAHLMEO_01391 1.5e-123 narI 1.7.5.1 C nitrate reductase, gamma
JOAHLMEO_01392 6.4e-287 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JOAHLMEO_01393 0.0 ywjA V ABC transporter
JOAHLMEO_01394 5e-93 ywjB H RibD C-terminal domain
JOAHLMEO_01395 2.7e-42 ywjC
JOAHLMEO_01396 1.2e-182 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
JOAHLMEO_01397 4.4e-222 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
JOAHLMEO_01398 0.0 fadF C COG0247 Fe-S oxidoreductase
JOAHLMEO_01399 1.4e-209 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
JOAHLMEO_01400 4.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
JOAHLMEO_01401 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
JOAHLMEO_01402 1.8e-90 ywjG S Domain of unknown function (DUF2529)
JOAHLMEO_01403 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
JOAHLMEO_01404 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
JOAHLMEO_01405 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JOAHLMEO_01406 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JOAHLMEO_01407 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
JOAHLMEO_01408 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JOAHLMEO_01409 1.1e-32 rpmE J Binds the 23S rRNA
JOAHLMEO_01410 5.4e-104 tdk 2.7.1.21 F thymidine kinase
JOAHLMEO_01411 0.0 sfcA 1.1.1.38 C malic enzyme
JOAHLMEO_01412 8.6e-160 ywkB S Membrane transport protein
JOAHLMEO_01413 3.5e-89 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
JOAHLMEO_01414 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JOAHLMEO_01415 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JOAHLMEO_01416 6.6e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
JOAHLMEO_01418 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
JOAHLMEO_01419 6.1e-112 spoIIR S stage II sporulation protein R
JOAHLMEO_01420 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
JOAHLMEO_01421 2.6e-194 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
JOAHLMEO_01422 1.7e-91 mntP P Probably functions as a manganese efflux pump
JOAHLMEO_01423 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JOAHLMEO_01424 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
JOAHLMEO_01425 7.2e-95 ywlG S Belongs to the UPF0340 family
JOAHLMEO_01426 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
JOAHLMEO_01427 2e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JOAHLMEO_01428 3.5e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
JOAHLMEO_01429 1e-108 yttP K Transcriptional regulator
JOAHLMEO_01430 2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
JOAHLMEO_01431 8.2e-310 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
JOAHLMEO_01432 1.3e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JOAHLMEO_01434 6.7e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JOAHLMEO_01435 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
JOAHLMEO_01436 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
JOAHLMEO_01437 3.5e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
JOAHLMEO_01438 6.1e-224 acuC BQ histone deacetylase
JOAHLMEO_01439 4e-125 motS N Flagellar motor protein
JOAHLMEO_01440 2.1e-146 motA N flagellar motor
JOAHLMEO_01441 3.8e-182 ccpA K catabolite control protein A
JOAHLMEO_01442 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
JOAHLMEO_01443 6.3e-54 ytxJ O Protein of unknown function (DUF2847)
JOAHLMEO_01444 6.6e-17 ytxH S COG4980 Gas vesicle protein
JOAHLMEO_01445 2.8e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JOAHLMEO_01446 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
JOAHLMEO_01447 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
JOAHLMEO_01448 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JOAHLMEO_01449 9.8e-149 ytpQ S Belongs to the UPF0354 family
JOAHLMEO_01450 1.3e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
JOAHLMEO_01451 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
JOAHLMEO_01452 4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
JOAHLMEO_01453 2.2e-51 ytzB S small secreted protein
JOAHLMEO_01454 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
JOAHLMEO_01455 2.7e-149 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
JOAHLMEO_01456 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
JOAHLMEO_01457 2e-45 ytzH S YtzH-like protein
JOAHLMEO_01458 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
JOAHLMEO_01459 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
JOAHLMEO_01460 6.6e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
JOAHLMEO_01461 2.9e-165 ytlQ
JOAHLMEO_01462 7.5e-100 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JOAHLMEO_01463 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
JOAHLMEO_01464 1.5e-269 pepV 3.5.1.18 E Dipeptidase
JOAHLMEO_01465 7.2e-226 pbuO S permease
JOAHLMEO_01466 3.8e-202 ythQ U Bacterial ABC transporter protein EcsB
JOAHLMEO_01467 1.3e-131 ythP V ABC transporter
JOAHLMEO_01468 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
JOAHLMEO_01469 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
JOAHLMEO_01470 1.5e-292 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JOAHLMEO_01471 4.6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
JOAHLMEO_01472 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
JOAHLMEO_01473 1.6e-140 ybbA S Putative esterase
JOAHLMEO_01474 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOAHLMEO_01475 1.8e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOAHLMEO_01476 1.6e-153 feuA P Iron-uptake system-binding protein
JOAHLMEO_01477 3e-303 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
JOAHLMEO_01478 2.7e-238 ybbC 3.2.1.52 S protein conserved in bacteria
JOAHLMEO_01479 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
JOAHLMEO_01480 1.6e-252 yfeW 3.4.16.4 V Belongs to the UPF0214 family
JOAHLMEO_01481 2e-231 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JOAHLMEO_01482 1.2e-149 ybbH K transcriptional
JOAHLMEO_01483 9.7e-161 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JOAHLMEO_01484 1.9e-86 ybbJ J acetyltransferase
JOAHLMEO_01485 9.6e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
JOAHLMEO_01491 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
JOAHLMEO_01492 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
JOAHLMEO_01493 6.1e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JOAHLMEO_01494 3e-225 ybbR S protein conserved in bacteria
JOAHLMEO_01495 7.9e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JOAHLMEO_01496 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
JOAHLMEO_01497 4.3e-169 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JOAHLMEO_01498 3.8e-119 adaA 3.2.2.21 K Transcriptional regulator
JOAHLMEO_01499 2.6e-97 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JOAHLMEO_01500 2.2e-271 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
JOAHLMEO_01501 0.0 ybcC S Belongs to the UPF0753 family
JOAHLMEO_01502 3.6e-91 can 4.2.1.1 P carbonic anhydrase
JOAHLMEO_01504 8.7e-47
JOAHLMEO_01505 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
JOAHLMEO_01506 5.1e-50 ybzH K Helix-turn-helix domain
JOAHLMEO_01507 6.5e-202 ybcL EGP Major facilitator Superfamily
JOAHLMEO_01508 4.9e-57
JOAHLMEO_01509 3.4e-180 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
JOAHLMEO_01510 1.3e-122 T Transcriptional regulatory protein, C terminal
JOAHLMEO_01511 2.9e-171 T His Kinase A (phospho-acceptor) domain
JOAHLMEO_01513 4.5e-135 KLT Protein tyrosine kinase
JOAHLMEO_01514 1.3e-151 ybdN
JOAHLMEO_01515 8.8e-215 ybdO S Domain of unknown function (DUF4885)
JOAHLMEO_01516 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
JOAHLMEO_01517 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
JOAHLMEO_01518 4.9e-30 ybxH S Family of unknown function (DUF5370)
JOAHLMEO_01519 2.8e-148 ybxI 3.5.2.6 V beta-lactamase
JOAHLMEO_01520 7.8e-08
JOAHLMEO_01522 4.9e-179 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JOAHLMEO_01523 5.2e-84 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
JOAHLMEO_01524 4.5e-126 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
JOAHLMEO_01525 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
JOAHLMEO_01526 1.4e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JOAHLMEO_01527 0.0 ydiF S ABC transporter
JOAHLMEO_01528 7.2e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
JOAHLMEO_01529 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JOAHLMEO_01530 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
JOAHLMEO_01531 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JOAHLMEO_01532 2.9e-27 ydiK S Domain of unknown function (DUF4305)
JOAHLMEO_01533 7.9e-129 ydiL S CAAX protease self-immunity
JOAHLMEO_01534 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JOAHLMEO_01535 2.8e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
JOAHLMEO_01536 2.4e-24 S SMI1-KNR4 cell-wall
JOAHLMEO_01537 2.9e-17 3.1.21.3 V Type I restriction modification DNA specificity domain
JOAHLMEO_01542 9.3e-61 V abc transporter atp-binding protein
JOAHLMEO_01543 0.0 K NB-ARC domain
JOAHLMEO_01544 4.7e-199 gutB 1.1.1.14 E Dehydrogenase
JOAHLMEO_01545 9.6e-253 gutA G MFS/sugar transport protein
JOAHLMEO_01546 6.8e-173 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
JOAHLMEO_01547 2.5e-113 pspA KT Phage shock protein A
JOAHLMEO_01548 1.7e-177 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JOAHLMEO_01549 6.5e-134 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
JOAHLMEO_01550 4.1e-149 ydjI S virion core protein (lumpy skin disease virus)
JOAHLMEO_01551 6.7e-195 S Ion transport 2 domain protein
JOAHLMEO_01552 1.7e-257 iolT EGP Major facilitator Superfamily
JOAHLMEO_01553 3.4e-194 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
JOAHLMEO_01554 4.5e-64 ydjM M Lytic transglycolase
JOAHLMEO_01555 1.2e-154 ydjN U Involved in the tonB-independent uptake of proteins
JOAHLMEO_01557 1.2e-34 ydjO S Cold-inducible protein YdjO
JOAHLMEO_01558 3.1e-158 ydjP I Alpha/beta hydrolase family
JOAHLMEO_01559 1.9e-178 yeaA S Protein of unknown function (DUF4003)
JOAHLMEO_01560 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
JOAHLMEO_01561 9.7e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
JOAHLMEO_01562 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JOAHLMEO_01563 2.1e-174 yeaC S COG0714 MoxR-like ATPases
JOAHLMEO_01564 7.1e-220 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
JOAHLMEO_01565 0.0 yebA E COG1305 Transglutaminase-like enzymes
JOAHLMEO_01566 1.5e-169 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
JOAHLMEO_01567 4.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JOAHLMEO_01568 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
JOAHLMEO_01569 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JOAHLMEO_01570 1.1e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
JOAHLMEO_01571 1.1e-107 ytaF P Probably functions as a manganese efflux pump
JOAHLMEO_01572 4.9e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JOAHLMEO_01573 8.9e-161 ytbE S reductase
JOAHLMEO_01574 2.4e-204 ytbD EGP Major facilitator Superfamily
JOAHLMEO_01575 9.9e-67 ytcD K Transcriptional regulator
JOAHLMEO_01576 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
JOAHLMEO_01577 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JOAHLMEO_01578 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JOAHLMEO_01579 3.8e-265 dnaB L Membrane attachment protein
JOAHLMEO_01580 1.1e-172 dnaI L Primosomal protein DnaI
JOAHLMEO_01581 1.1e-107 ytxB S SNARE associated Golgi protein
JOAHLMEO_01582 3.5e-157 ytxC S YtxC-like family
JOAHLMEO_01584 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JOAHLMEO_01585 1.5e-146 ysaA S HAD-hyrolase-like
JOAHLMEO_01586 0.0 lytS 2.7.13.3 T Histidine kinase
JOAHLMEO_01587 7e-130 lytT T COG3279 Response regulator of the LytR AlgR family
JOAHLMEO_01588 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
JOAHLMEO_01589 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
JOAHLMEO_01591 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JOAHLMEO_01592 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
JOAHLMEO_01593 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JOAHLMEO_01594 7.5e-45 ysdA S Membrane
JOAHLMEO_01595 9.2e-68 ysdB S Sigma-w pathway protein YsdB
JOAHLMEO_01596 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
JOAHLMEO_01597 3.1e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
JOAHLMEO_01598 6e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
JOAHLMEO_01599 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
JOAHLMEO_01600 2.4e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
JOAHLMEO_01601 4.7e-143 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
JOAHLMEO_01602 6.3e-221 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
JOAHLMEO_01603 5.8e-252 araN G carbohydrate transport
JOAHLMEO_01604 1.4e-167 araP G carbohydrate transport
JOAHLMEO_01605 2.9e-143 araQ G transport system permease
JOAHLMEO_01606 2.3e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
JOAHLMEO_01607 0.0 cstA T Carbon starvation protein
JOAHLMEO_01608 9.6e-54 ysfE 4.4.1.5 E Glyoxalase-like domain
JOAHLMEO_01609 8.9e-256 glcF C Glycolate oxidase
JOAHLMEO_01610 2e-261 glcD 1.1.3.15 C Glycolate oxidase subunit
JOAHLMEO_01611 7.3e-203 ysfB KT regulator
JOAHLMEO_01612 2.6e-32 sspI S Belongs to the SspI family
JOAHLMEO_01613 1.6e-132 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JOAHLMEO_01614 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JOAHLMEO_01615 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JOAHLMEO_01616 4e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JOAHLMEO_01617 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JOAHLMEO_01618 1.7e-85 cvpA S membrane protein, required for colicin V production
JOAHLMEO_01619 0.0 polX L COG1796 DNA polymerase IV (family X)
JOAHLMEO_01620 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
JOAHLMEO_01621 7.3e-68 yshE S membrane
JOAHLMEO_01622 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
JOAHLMEO_01623 4e-99 fadR K Transcriptional regulator
JOAHLMEO_01624 1.6e-135 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
JOAHLMEO_01625 4.5e-135 etfB C Electron transfer flavoprotein
JOAHLMEO_01626 6.7e-176 etfA C Electron transfer flavoprotein
JOAHLMEO_01628 2.9e-300 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
JOAHLMEO_01629 2e-52 trxA O Belongs to the thioredoxin family
JOAHLMEO_01630 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
JOAHLMEO_01631 6.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
JOAHLMEO_01632 1.2e-79 yslB S Protein of unknown function (DUF2507)
JOAHLMEO_01633 2.4e-107 sdhC C succinate dehydrogenase
JOAHLMEO_01634 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
JOAHLMEO_01635 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
JOAHLMEO_01636 5.5e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
JOAHLMEO_01637 3.3e-30 gerE K Transcriptional regulator
JOAHLMEO_01638 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
JOAHLMEO_01639 2.1e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
JOAHLMEO_01640 3.8e-196 gerM S COG5401 Spore germination protein
JOAHLMEO_01641 3.4e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JOAHLMEO_01642 4.5e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JOAHLMEO_01643 2.6e-91 ysnB S Phosphoesterase
JOAHLMEO_01645 1e-132 ysnF S protein conserved in bacteria
JOAHLMEO_01646 1.5e-135 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
JOAHLMEO_01647 1.4e-75 ysnE K acetyltransferase
JOAHLMEO_01649 0.0 ilvB 2.2.1.6 E Acetolactate synthase
JOAHLMEO_01650 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
JOAHLMEO_01651 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JOAHLMEO_01652 1.6e-288 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JOAHLMEO_01653 5.7e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
JOAHLMEO_01654 8.2e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JOAHLMEO_01655 4e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JOAHLMEO_01656 1.2e-185 ysoA H Tetratricopeptide repeat
JOAHLMEO_01657 4.1e-226 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
JOAHLMEO_01658 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JOAHLMEO_01659 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
JOAHLMEO_01660 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JOAHLMEO_01661 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
JOAHLMEO_01662 1.4e-89 ysxD
JOAHLMEO_01663 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JOAHLMEO_01664 3.6e-146 hemX O cytochrome C
JOAHLMEO_01665 3.3e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
JOAHLMEO_01666 8.4e-145 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
JOAHLMEO_01667 2.8e-182 hemB 4.2.1.24 H Belongs to the ALAD family
JOAHLMEO_01668 1.5e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
JOAHLMEO_01669 6.4e-222 spoVID M stage VI sporulation protein D
JOAHLMEO_01670 1.5e-197 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JOAHLMEO_01671 1.6e-25
JOAHLMEO_01672 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
JOAHLMEO_01673 4.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
JOAHLMEO_01674 1.5e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
JOAHLMEO_01675 7.3e-162 spoIIB S Sporulation related domain
JOAHLMEO_01676 8.3e-102 maf D septum formation protein Maf
JOAHLMEO_01677 5.9e-126 radC E Belongs to the UPF0758 family
JOAHLMEO_01678 1.8e-184 mreB D Rod shape-determining protein MreB
JOAHLMEO_01679 1.1e-156 mreC M Involved in formation and maintenance of cell shape
JOAHLMEO_01680 1.4e-84 mreD M shape-determining protein
JOAHLMEO_01681 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
JOAHLMEO_01682 2.5e-144 minD D Belongs to the ParA family
JOAHLMEO_01683 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
JOAHLMEO_01684 5.9e-160 spoIVFB S Stage IV sporulation protein
JOAHLMEO_01685 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
JOAHLMEO_01686 4.1e-56 ysxB J ribosomal protein
JOAHLMEO_01687 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
JOAHLMEO_01688 1.9e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
JOAHLMEO_01689 5.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JOAHLMEO_01690 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
JOAHLMEO_01691 1.3e-162 pheA 4.2.1.51 E Prephenate dehydratase
JOAHLMEO_01692 5.1e-93 niaR S small molecule binding protein (contains 3H domain)
JOAHLMEO_01693 3.1e-228 nifS 2.8.1.7 E Cysteine desulfurase
JOAHLMEO_01694 3.9e-298 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
JOAHLMEO_01695 7.3e-158 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
JOAHLMEO_01696 5.4e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JOAHLMEO_01697 4.8e-157 safA M spore coat assembly protein SafA
JOAHLMEO_01698 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
JOAHLMEO_01699 3.6e-126 yebC K transcriptional regulatory protein
JOAHLMEO_01700 2.2e-260 alsT E Sodium alanine symporter
JOAHLMEO_01701 1.2e-50 S Family of unknown function (DUF5412)
JOAHLMEO_01703 7.2e-118 yrzF T serine threonine protein kinase
JOAHLMEO_01704 1.1e-192 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
JOAHLMEO_01705 5.3e-253 csbX EGP Major facilitator Superfamily
JOAHLMEO_01706 4.8e-93 bofC S BofC C-terminal domain
JOAHLMEO_01707 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
JOAHLMEO_01708 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
JOAHLMEO_01709 6.9e-19 yrzS S Protein of unknown function (DUF2905)
JOAHLMEO_01710 7.5e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JOAHLMEO_01711 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
JOAHLMEO_01712 8e-39 yajC U Preprotein translocase subunit YajC
JOAHLMEO_01713 1.2e-74 yrzE S Protein of unknown function (DUF3792)
JOAHLMEO_01714 9.2e-113 yrbG S membrane
JOAHLMEO_01715 8.2e-269 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JOAHLMEO_01716 1.6e-48 yrzD S Post-transcriptional regulator
JOAHLMEO_01717 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JOAHLMEO_01718 1.9e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
JOAHLMEO_01719 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
JOAHLMEO_01720 6.6e-229 ylbM S Belongs to the UPF0348 family
JOAHLMEO_01722 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
JOAHLMEO_01723 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
JOAHLMEO_01724 2.2e-73 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
JOAHLMEO_01725 1.5e-88 ylbP K n-acetyltransferase
JOAHLMEO_01726 8.9e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JOAHLMEO_01727 1.2e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
JOAHLMEO_01728 2.9e-78 mraZ K Belongs to the MraZ family
JOAHLMEO_01729 1.6e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
JOAHLMEO_01730 3.7e-44 ftsL D Essential cell division protein
JOAHLMEO_01731 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
JOAHLMEO_01732 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
JOAHLMEO_01733 1.2e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JOAHLMEO_01734 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JOAHLMEO_01735 1.3e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JOAHLMEO_01736 5.7e-186 spoVE D Belongs to the SEDS family
JOAHLMEO_01737 4.3e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JOAHLMEO_01738 5.3e-167 murB 1.3.1.98 M cell wall formation
JOAHLMEO_01739 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
JOAHLMEO_01740 4.1e-103 ylxW S protein conserved in bacteria
JOAHLMEO_01741 2.8e-117 ylxX S protein conserved in bacteria
JOAHLMEO_01742 6.2e-58 sbp S small basic protein
JOAHLMEO_01743 1.2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
JOAHLMEO_01744 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JOAHLMEO_01745 0.0 bpr O COG1404 Subtilisin-like serine proteases
JOAHLMEO_01746 4.1e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
JOAHLMEO_01747 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JOAHLMEO_01748 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JOAHLMEO_01749 2.4e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
JOAHLMEO_01750 6.8e-253 argE 3.5.1.16 E Acetylornithine deacetylase
JOAHLMEO_01751 2.4e-37 ylmC S sporulation protein
JOAHLMEO_01752 2.4e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
JOAHLMEO_01753 6.5e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JOAHLMEO_01754 5.1e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
JOAHLMEO_01755 1.6e-39 yggT S membrane
JOAHLMEO_01756 2e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
JOAHLMEO_01757 2.6e-67 divIVA D Cell division initiation protein
JOAHLMEO_01758 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JOAHLMEO_01759 1.3e-63 dksA T COG1734 DnaK suppressor protein
JOAHLMEO_01760 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JOAHLMEO_01761 1.2e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JOAHLMEO_01762 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JOAHLMEO_01763 1.6e-168 yugK C Dehydrogenase
JOAHLMEO_01764 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
JOAHLMEO_01766 1.7e-72 yugN S YugN-like family
JOAHLMEO_01767 2.2e-182 yugO P COG1226 Kef-type K transport systems
JOAHLMEO_01768 3.2e-53 mstX S Membrane-integrating protein Mistic
JOAHLMEO_01769 2.3e-38
JOAHLMEO_01770 1.4e-116 yugP S Zn-dependent protease
JOAHLMEO_01771 2.9e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
JOAHLMEO_01772 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
JOAHLMEO_01773 4.1e-71 yugU S Uncharacterised protein family UPF0047
JOAHLMEO_01774 1e-35
JOAHLMEO_01775 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
JOAHLMEO_01776 3.5e-224 mcpA NT chemotaxis protein
JOAHLMEO_01777 2.8e-221 mcpA NT chemotaxis protein
JOAHLMEO_01778 5.2e-292 mcpA NT chemotaxis protein
JOAHLMEO_01779 7.3e-238 mcpA NT chemotaxis protein
JOAHLMEO_01780 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
JOAHLMEO_01781 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
JOAHLMEO_01782 3.3e-272 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
JOAHLMEO_01783 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
JOAHLMEO_01784 1.3e-248 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
JOAHLMEO_01785 3.7e-182 ygjR S Oxidoreductase
JOAHLMEO_01786 3.7e-189 yubA S transporter activity
JOAHLMEO_01787 5.9e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
JOAHLMEO_01789 3.2e-86 cdoA 1.13.11.20 S Cysteine dioxygenase type I
JOAHLMEO_01790 4.9e-274 yubD P Major Facilitator Superfamily
JOAHLMEO_01791 3.2e-152 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
JOAHLMEO_01792 1e-38 yiaA S yiaA/B two helix domain
JOAHLMEO_01793 6e-236 ktrB P Potassium
JOAHLMEO_01794 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
JOAHLMEO_01795 2.2e-91 yuaB
JOAHLMEO_01796 5.5e-95 yuaC K Belongs to the GbsR family
JOAHLMEO_01797 5.2e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
JOAHLMEO_01798 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
JOAHLMEO_01799 1.1e-106 yuaD
JOAHLMEO_01800 3.9e-84 yuaE S DinB superfamily
JOAHLMEO_01801 4.2e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
JOAHLMEO_01802 7e-188 yuaG 3.4.21.72 S protein conserved in bacteria
JOAHLMEO_01803 5.5e-92 M1-753 M FR47-like protein
JOAHLMEO_01804 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
JOAHLMEO_01805 1.3e-63 hxlR K transcriptional
JOAHLMEO_01806 3.1e-105 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
JOAHLMEO_01807 1.9e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
JOAHLMEO_01808 7.3e-186 tlpC 2.7.13.3 NT chemotaxis protein
JOAHLMEO_01809 7.8e-71 nucA M Deoxyribonuclease NucA/NucB
JOAHLMEO_01810 5e-69 nin S Competence protein J (ComJ)
JOAHLMEO_01811 5.5e-296 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JOAHLMEO_01812 2.7e-121 S AAA domain
JOAHLMEO_01813 9.3e-24
JOAHLMEO_01814 5.7e-39 K MarR family
JOAHLMEO_01815 2.3e-51 yckD S Protein of unknown function (DUF2680)
JOAHLMEO_01816 2.6e-35 yckC S membrane
JOAHLMEO_01818 4e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
JOAHLMEO_01819 5.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
JOAHLMEO_01820 2e-227 yciC S GTPases (G3E family)
JOAHLMEO_01821 3.9e-107 yciB M ErfK YbiS YcfS YnhG
JOAHLMEO_01822 9.3e-172 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
JOAHLMEO_01823 1.7e-221 nasA P COG2223 Nitrate nitrite transporter
JOAHLMEO_01824 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
JOAHLMEO_01825 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JOAHLMEO_01826 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JOAHLMEO_01827 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
JOAHLMEO_01828 1.4e-275 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
JOAHLMEO_01829 9.3e-189 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
JOAHLMEO_01830 5.9e-160 I alpha/beta hydrolase fold
JOAHLMEO_01831 1.2e-139 ycgR S permeases
JOAHLMEO_01832 2.8e-146 ycgQ S membrane
JOAHLMEO_01833 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
JOAHLMEO_01834 2e-261 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JOAHLMEO_01835 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
JOAHLMEO_01836 5.1e-170 ycgM E Proline dehydrogenase
JOAHLMEO_01837 1.1e-144 ycgL S Predicted nucleotidyltransferase
JOAHLMEO_01838 5.2e-47 recJ L Single-stranded-DNA-specific exonuclease RecJ
JOAHLMEO_01839 2.3e-90 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JOAHLMEO_01840 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JOAHLMEO_01841 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
JOAHLMEO_01842 2.2e-261 lytH 3.5.1.28 M COG3103 SH3 domain protein
JOAHLMEO_01844 1.3e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
JOAHLMEO_01845 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JOAHLMEO_01846 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
JOAHLMEO_01847 3.3e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
JOAHLMEO_01848 1.2e-70 cymR K Transcriptional regulator
JOAHLMEO_01849 2.6e-211 iscS 2.8.1.7 E Cysteine desulfurase
JOAHLMEO_01850 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
JOAHLMEO_01851 1.4e-15 S COG0457 FOG TPR repeat
JOAHLMEO_01852 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
JOAHLMEO_01853 3.9e-81 yrrD S protein conserved in bacteria
JOAHLMEO_01854 9.8e-31 yrzR
JOAHLMEO_01855 8e-08 S Protein of unknown function (DUF3918)
JOAHLMEO_01856 7.6e-107 glnP P ABC transporter
JOAHLMEO_01857 1.8e-108 gluC P ABC transporter
JOAHLMEO_01858 4.3e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
JOAHLMEO_01859 1.2e-129 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
JOAHLMEO_01860 2.7e-170 yrrI S AI-2E family transporter
JOAHLMEO_01861 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JOAHLMEO_01862 1.7e-41 yrzL S Belongs to the UPF0297 family
JOAHLMEO_01863 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JOAHLMEO_01864 1.2e-45 yrzB S Belongs to the UPF0473 family
JOAHLMEO_01865 3.7e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JOAHLMEO_01866 2.9e-119 yrrM 2.1.1.104 S O-methyltransferase
JOAHLMEO_01867 4.3e-172 yegQ O Peptidase U32
JOAHLMEO_01868 2.7e-246 yegQ O COG0826 Collagenase and related proteases
JOAHLMEO_01869 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
JOAHLMEO_01870 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
JOAHLMEO_01871 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
JOAHLMEO_01872 4.2e-63 yrrS S Protein of unknown function (DUF1510)
JOAHLMEO_01873 1e-25 yrzA S Protein of unknown function (DUF2536)
JOAHLMEO_01874 8.4e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
JOAHLMEO_01875 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JOAHLMEO_01876 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
JOAHLMEO_01877 5.9e-208 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
JOAHLMEO_01878 4.6e-35 yrhC S YrhC-like protein
JOAHLMEO_01879 7e-84 L Belongs to the 'phage' integrase family
JOAHLMEO_01880 7e-39 immA E Pfam:DUF955
JOAHLMEO_01881 1.4e-28 yvaO K Transcriptional
JOAHLMEO_01892 8.9e-83 ydcK S Belongs to the SprT family
JOAHLMEO_01893 0.0 yhgF K COG2183 Transcriptional accessory protein
JOAHLMEO_01894 1.1e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
JOAHLMEO_01895 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JOAHLMEO_01896 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
JOAHLMEO_01897 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
JOAHLMEO_01898 7.1e-189 rsbU 3.1.3.3 KT phosphatase
JOAHLMEO_01899 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
JOAHLMEO_01900 5.2e-57 rsbS T antagonist
JOAHLMEO_01901 1.3e-143 rsbR T Positive regulator of sigma-B
JOAHLMEO_01902 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
JOAHLMEO_01903 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
JOAHLMEO_01904 1.9e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JOAHLMEO_01905 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
JOAHLMEO_01906 8e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
JOAHLMEO_01907 5.8e-106 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
JOAHLMEO_01908 5.1e-260 ydbT S Membrane
JOAHLMEO_01909 2.1e-82 ydbS S Bacterial PH domain
JOAHLMEO_01910 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
JOAHLMEO_01911 6.7e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
JOAHLMEO_01912 1.1e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
JOAHLMEO_01913 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
JOAHLMEO_01914 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JOAHLMEO_01915 2.2e-07 S Fur-regulated basic protein A
JOAHLMEO_01916 1.1e-18 S Fur-regulated basic protein B
JOAHLMEO_01917 8.3e-218 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
JOAHLMEO_01918 2.7e-52 ydbL
JOAHLMEO_01919 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
JOAHLMEO_01920 1.8e-170 ydbJ V ABC transporter, ATP-binding protein
JOAHLMEO_01921 4.4e-181 ydbI S AI-2E family transporter
JOAHLMEO_01922 1.4e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
JOAHLMEO_01923 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
JOAHLMEO_01924 1.5e-294 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
JOAHLMEO_01925 6.7e-198 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
JOAHLMEO_01926 1.8e-153 ydbD P Catalase
JOAHLMEO_01927 4.1e-62 ydbC S Domain of unknown function (DUF4937
JOAHLMEO_01928 8.9e-59 ydbB G Cupin domain
JOAHLMEO_01930 1.2e-146 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
JOAHLMEO_01931 1.6e-76 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
JOAHLMEO_01933 1.3e-224 mntH P H( )-stimulated, divalent metal cation uptake system
JOAHLMEO_01934 6.4e-41 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JOAHLMEO_01935 1.8e-150 S Alpha beta hydrolase
JOAHLMEO_01936 2.2e-60 T sh3 domain protein
JOAHLMEO_01937 5.4e-61 T sh3 domain protein
JOAHLMEO_01939 3e-63 E Glyoxalase-like domain
JOAHLMEO_01940 2.6e-36 yraG
JOAHLMEO_01941 6.4e-63 yraF M Spore coat protein
JOAHLMEO_01942 5.1e-220 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
JOAHLMEO_01943 7.5e-26 yraE
JOAHLMEO_01944 3.3e-49 yraD M Spore coat protein
JOAHLMEO_01945 4.3e-47 yraB K helix_turn_helix, mercury resistance
JOAHLMEO_01946 2.8e-196 adhA 1.1.1.1 C alcohol dehydrogenase
JOAHLMEO_01947 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
JOAHLMEO_01948 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
JOAHLMEO_01949 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
JOAHLMEO_01950 2.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
JOAHLMEO_01951 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
JOAHLMEO_01952 1.5e-74 levD 2.7.1.202 G PTS system fructose IIA component
JOAHLMEO_01953 0.0 levR K PTS system fructose IIA component
JOAHLMEO_01954 6.6e-254 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
JOAHLMEO_01955 1.1e-105 yrhP E LysE type translocator
JOAHLMEO_01956 7e-150 yrhO K Archaeal transcriptional regulator TrmB
JOAHLMEO_01957 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
JOAHLMEO_01958 5.5e-150 rsiV S Protein of unknown function (DUF3298)
JOAHLMEO_01959 0.0 yrhL I Acyltransferase family
JOAHLMEO_01960 9.1e-44 yrhK S YrhK-like protein
JOAHLMEO_01961 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
JOAHLMEO_01962 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
JOAHLMEO_01963 1.1e-95 yrhH Q methyltransferase
JOAHLMEO_01965 3e-142 focA P Formate nitrite
JOAHLMEO_01966 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
JOAHLMEO_01967 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
JOAHLMEO_01968 5.4e-78 yrhD S Protein of unknown function (DUF1641)
JOAHLMEO_01969 1.9e-34 C Domain of unknown function (DUF4145)
JOAHLMEO_01971 4.9e-64 S response regulator aspartate phosphatase
JOAHLMEO_01972 8.2e-268 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
JOAHLMEO_01973 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
JOAHLMEO_01974 1e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
JOAHLMEO_01975 1.9e-172 yfnG 4.2.1.45 M dehydratase
JOAHLMEO_01976 5.4e-180 yfnF M Nucleotide-diphospho-sugar transferase
JOAHLMEO_01977 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
JOAHLMEO_01978 3.9e-189 yfnD M Nucleotide-diphospho-sugar transferase
JOAHLMEO_01979 1.7e-205 fsr P COG0477 Permeases of the major facilitator superfamily
JOAHLMEO_01980 2.5e-132 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
JOAHLMEO_01981 1.4e-240 yfnA E amino acid
JOAHLMEO_01982 9e-278 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
JOAHLMEO_01983 1.1e-113 yfmS NT chemotaxis protein
JOAHLMEO_01984 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
JOAHLMEO_01985 5.2e-75 yfmQ S Uncharacterised protein from bacillus cereus group
JOAHLMEO_01986 9e-69 yfmP K transcriptional
JOAHLMEO_01987 9.5e-209 yfmO EGP Major facilitator Superfamily
JOAHLMEO_01988 7.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
JOAHLMEO_01989 5e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
JOAHLMEO_01990 6.8e-75 yfmK 2.3.1.128 K acetyltransferase
JOAHLMEO_01991 6.7e-187 yfmJ S N-terminal domain of oxidoreductase
JOAHLMEO_01992 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
JOAHLMEO_01993 3.6e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOAHLMEO_01994 6.2e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOAHLMEO_01995 1.2e-166 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
JOAHLMEO_01996 2.6e-24 S Protein of unknown function (DUF3212)
JOAHLMEO_01997 7.6e-58 yflT S Heat induced stress protein YflT
JOAHLMEO_01998 2.5e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
JOAHLMEO_01999 5.5e-235 yflS P Sodium:sulfate symporter transmembrane region
JOAHLMEO_02000 4.1e-287 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
JOAHLMEO_02001 2.4e-116 citT T response regulator
JOAHLMEO_02002 1.1e-178 yflP S Tripartite tricarboxylate transporter family receptor
JOAHLMEO_02003 1.9e-226 citM C Citrate transporter
JOAHLMEO_02004 2.1e-151 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
JOAHLMEO_02005 5.2e-90
JOAHLMEO_02006 2.7e-55
JOAHLMEO_02007 6.9e-207 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
JOAHLMEO_02008 2.9e-89 ggaA M Glycosyltransferase like family 2
JOAHLMEO_02009 2.5e-145 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JOAHLMEO_02010 9.5e-57 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
JOAHLMEO_02011 7.8e-87 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
JOAHLMEO_02012 1.5e-105 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JOAHLMEO_02013 2.6e-105 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
JOAHLMEO_02014 4e-147 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
JOAHLMEO_02015 2.2e-88 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
JOAHLMEO_02016 2.5e-192 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
JOAHLMEO_02017 3.4e-214 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
JOAHLMEO_02018 2.3e-189 pmi 5.3.1.8 G mannose-6-phosphate isomerase
JOAHLMEO_02019 1.5e-264 gerBA EG Spore germination protein
JOAHLMEO_02020 8.1e-194 gerBB E Spore germination protein
JOAHLMEO_02021 2.2e-207 gerAC S Spore germination protein
JOAHLMEO_02022 7.8e-247 ywtG EGP Major facilitator Superfamily
JOAHLMEO_02023 2.4e-170 ywtF K Transcriptional regulator
JOAHLMEO_02024 9.1e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
JOAHLMEO_02025 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
JOAHLMEO_02026 3.6e-21 ywtC
JOAHLMEO_02027 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
JOAHLMEO_02028 8.6e-70 pgsC S biosynthesis protein
JOAHLMEO_02029 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
JOAHLMEO_02030 5.5e-178 rbsR K transcriptional
JOAHLMEO_02031 8.4e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JOAHLMEO_02032 5.8e-62 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
JOAHLMEO_02033 3.3e-275 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
JOAHLMEO_02034 5.5e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
JOAHLMEO_02035 2.2e-162 yurL 2.7.1.218 G pfkB family carbohydrate kinase
JOAHLMEO_02036 8.1e-168 yurM P COG0395 ABC-type sugar transport system, permease component
JOAHLMEO_02037 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
JOAHLMEO_02038 4.7e-238 yurO G COG1653 ABC-type sugar transport system, periplasmic component
JOAHLMEO_02039 1.3e-182 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
JOAHLMEO_02040 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
JOAHLMEO_02041 8.4e-207 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
JOAHLMEO_02043 1e-41
JOAHLMEO_02044 2.3e-63 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JOAHLMEO_02045 3.5e-271 sufB O FeS cluster assembly
JOAHLMEO_02046 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
JOAHLMEO_02047 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JOAHLMEO_02048 1.4e-245 sufD O assembly protein SufD
JOAHLMEO_02049 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
JOAHLMEO_02050 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JOAHLMEO_02051 7.2e-147 metQ P Belongs to the NlpA lipoprotein family
JOAHLMEO_02052 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
JOAHLMEO_02053 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JOAHLMEO_02054 2.4e-56 yusD S SCP-2 sterol transfer family
JOAHLMEO_02055 5.6e-55 traF CO Thioredoxin
JOAHLMEO_02056 1.6e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
JOAHLMEO_02057 4.1e-39 yusG S Protein of unknown function (DUF2553)
JOAHLMEO_02058 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
JOAHLMEO_02059 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
JOAHLMEO_02060 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
JOAHLMEO_02061 7.9e-216 fadA 2.3.1.16 I Belongs to the thiolase family
JOAHLMEO_02062 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
JOAHLMEO_02063 8.1e-09 S YuzL-like protein
JOAHLMEO_02064 8.4e-165 fadM E Proline dehydrogenase
JOAHLMEO_02065 5.1e-40
JOAHLMEO_02066 5.4e-53 yusN M Coat F domain
JOAHLMEO_02067 2.6e-66 yusO K Iron dependent repressor, N-terminal DNA binding domain
JOAHLMEO_02068 8.5e-293 yusP P Major facilitator superfamily
JOAHLMEO_02069 7.1e-65 yusQ S Tautomerase enzyme
JOAHLMEO_02070 5e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JOAHLMEO_02071 7.4e-158 yusT K LysR substrate binding domain
JOAHLMEO_02072 2.1e-38 yusU S Protein of unknown function (DUF2573)
JOAHLMEO_02073 5.1e-153 yusV 3.6.3.34 HP ABC transporter
JOAHLMEO_02074 1.9e-66 S YusW-like protein
JOAHLMEO_02075 1.1e-298 pepF2 E COG1164 Oligoendopeptidase F
JOAHLMEO_02076 2e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JOAHLMEO_02077 2.7e-79 dps P Ferritin-like domain
JOAHLMEO_02078 5.9e-76 yoaW
JOAHLMEO_02079 3.7e-157 yijE EG EamA-like transporter family
JOAHLMEO_02080 9.6e-158 yoaU K LysR substrate binding domain
JOAHLMEO_02081 8.2e-148 yoaT S Protein of unknown function (DUF817)
JOAHLMEO_02082 4.4e-30 yozG K Transcriptional regulator
JOAHLMEO_02083 3.6e-74 yoaS S Protein of unknown function (DUF2975)
JOAHLMEO_02084 7.1e-172 yoaR V vancomycin resistance protein
JOAHLMEO_02085 3.1e-84
JOAHLMEO_02088 4.6e-232 oxdC 4.1.1.2 G Oxalate decarboxylase
JOAHLMEO_02091 1.2e-131 yoqW S Belongs to the SOS response-associated peptidase family
JOAHLMEO_02092 4.7e-196 pelB 4.2.2.10, 4.2.2.2 G Amb_all
JOAHLMEO_02093 1.5e-110 yoaK S Membrane
JOAHLMEO_02094 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
JOAHLMEO_02095 1.8e-278 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
JOAHLMEO_02096 4.4e-183 mcpU NT methyl-accepting chemotaxis protein
JOAHLMEO_02097 8.2e-37 S Protein of unknown function (DUF4025)
JOAHLMEO_02098 7.7e-13
JOAHLMEO_02099 6.5e-08 ywlA S Uncharacterised protein family (UPF0715)
JOAHLMEO_02100 1.1e-33 yoaF
JOAHLMEO_02101 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JOAHLMEO_02102 1.5e-183 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JOAHLMEO_02103 5.1e-281 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
JOAHLMEO_02104 1.5e-233 yoaB EGP Major facilitator Superfamily
JOAHLMEO_02105 1.7e-93 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
JOAHLMEO_02106 1e-134 yoxB
JOAHLMEO_02107 7.7e-38 yoxC S Bacterial protein of unknown function (DUF948)
JOAHLMEO_02108 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
JOAHLMEO_02109 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
JOAHLMEO_02110 6.2e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JOAHLMEO_02111 1.5e-203 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JOAHLMEO_02112 7.8e-155 gltC K Transcriptional regulator
JOAHLMEO_02113 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
JOAHLMEO_02114 6.1e-12 yqfQ S YqfQ-like protein
JOAHLMEO_02115 1.2e-241 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
JOAHLMEO_02116 4.4e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JOAHLMEO_02117 2.1e-36 yqfT S Protein of unknown function (DUF2624)
JOAHLMEO_02118 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
JOAHLMEO_02119 4.2e-77 zur P Belongs to the Fur family
JOAHLMEO_02120 1e-107 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
JOAHLMEO_02121 4.3e-62 yqfX S membrane
JOAHLMEO_02122 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JOAHLMEO_02123 5.2e-47 yqfZ M LysM domain
JOAHLMEO_02124 3.9e-131 yqgB S Protein of unknown function (DUF1189)
JOAHLMEO_02125 4e-73 yqgC S protein conserved in bacteria
JOAHLMEO_02126 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
JOAHLMEO_02127 2.5e-231 yqgE EGP Major facilitator superfamily
JOAHLMEO_02128 0.0 pbpA 3.4.16.4 M penicillin-binding protein
JOAHLMEO_02129 6.2e-144 pstS P Phosphate
JOAHLMEO_02130 3.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
JOAHLMEO_02131 4.4e-158 pstA P Phosphate transport system permease
JOAHLMEO_02132 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JOAHLMEO_02133 1.4e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JOAHLMEO_02134 1.9e-75 yqzC S YceG-like family
JOAHLMEO_02135 9.2e-51 yqzD
JOAHLMEO_02137 2.3e-196 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
JOAHLMEO_02138 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
JOAHLMEO_02139 7.4e-103 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JOAHLMEO_02140 2.5e-09 yqgO
JOAHLMEO_02141 1.5e-259 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
JOAHLMEO_02142 3.1e-33 yqgQ S Protein conserved in bacteria
JOAHLMEO_02143 5.2e-181 glcK 2.7.1.2 G Glucokinase
JOAHLMEO_02144 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
JOAHLMEO_02145 7.9e-221 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
JOAHLMEO_02146 1.3e-196 yqgU
JOAHLMEO_02147 6.9e-50 yqgV S Thiamine-binding protein
JOAHLMEO_02148 8.9e-23 yqgW S Protein of unknown function (DUF2759)
JOAHLMEO_02149 8e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
JOAHLMEO_02150 1.8e-37 yqgY S Protein of unknown function (DUF2626)
JOAHLMEO_02151 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
JOAHLMEO_02153 8.6e-148 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
JOAHLMEO_02154 1.3e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
JOAHLMEO_02155 7.2e-175 corA P Mg2 transporter protein
JOAHLMEO_02157 1.1e-200 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JOAHLMEO_02158 6.9e-171 comGB NU COG1459 Type II secretory pathway, component PulF
JOAHLMEO_02159 1.5e-46 comGC U Required for transformation and DNA binding
JOAHLMEO_02160 4.9e-70 gspH NU protein transport across the cell outer membrane
JOAHLMEO_02161 4.5e-58 comGE
JOAHLMEO_02162 3.5e-45 comGF U Putative Competence protein ComGF
JOAHLMEO_02163 1.2e-43 S ComG operon protein 7
JOAHLMEO_02164 5.2e-26 yqzE S YqzE-like protein
JOAHLMEO_02165 7.3e-54 yqzG S Protein of unknown function (DUF3889)
JOAHLMEO_02166 3e-115 yqxM
JOAHLMEO_02167 6.7e-59 sipW 3.4.21.89 U Signal peptidase
JOAHLMEO_02168 1.9e-141 tasA S Cell division protein FtsN
JOAHLMEO_02169 1e-54 sinR K transcriptional
JOAHLMEO_02170 1.2e-24 sinI S Anti-repressor SinI
JOAHLMEO_02171 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
JOAHLMEO_02172 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
JOAHLMEO_02173 1.1e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
JOAHLMEO_02174 1.7e-254 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JOAHLMEO_02175 5.3e-286 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JOAHLMEO_02176 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
JOAHLMEO_02177 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
JOAHLMEO_02178 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
JOAHLMEO_02179 1.5e-163 yqhO S esterase of the alpha-beta hydrolase superfamily
JOAHLMEO_02180 2.2e-61 yqhP
JOAHLMEO_02181 3.4e-172 yqhQ S Protein of unknown function (DUF1385)
JOAHLMEO_02182 6.6e-93 yqhR S Conserved membrane protein YqhR
JOAHLMEO_02183 3.6e-76 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
JOAHLMEO_02184 1.4e-171 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
JOAHLMEO_02185 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JOAHLMEO_02186 7.9e-37 yqhV S Protein of unknown function (DUF2619)
JOAHLMEO_02187 3e-170 spoIIIAA S stage III sporulation protein AA
JOAHLMEO_02188 4.1e-84 spoIIIAB S Stage III sporulation protein
JOAHLMEO_02189 7.6e-29 spoIIIAC S stage III sporulation protein AC
JOAHLMEO_02190 2.3e-58 spoIIIAD S Stage III sporulation protein AD
JOAHLMEO_02191 2.9e-197 spoIIIAE S stage III sporulation protein AE
JOAHLMEO_02192 4.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
JOAHLMEO_02193 2.2e-109 spoIIIAG S stage III sporulation protein AG
JOAHLMEO_02194 9.9e-91 spoIIIAH S SpoIIIAH-like protein
JOAHLMEO_02195 1.1e-62 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
JOAHLMEO_02196 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
JOAHLMEO_02197 2.1e-67 yqhY S protein conserved in bacteria
JOAHLMEO_02198 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JOAHLMEO_02199 5.1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JOAHLMEO_02200 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
JOAHLMEO_02201 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
JOAHLMEO_02202 6.5e-162 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
JOAHLMEO_02203 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JOAHLMEO_02204 1.9e-155 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
JOAHLMEO_02205 5.6e-77 argR K Regulates arginine biosynthesis genes
JOAHLMEO_02206 6e-305 recN L May be involved in recombinational repair of damaged DNA
JOAHLMEO_02207 3.1e-237 rseP 3.4.21.116 M Stage IV sporulation protein B
JOAHLMEO_02208 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
JOAHLMEO_02210 4.7e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
JOAHLMEO_02211 6e-27
JOAHLMEO_02212 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
JOAHLMEO_02213 7.9e-129 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
JOAHLMEO_02214 3.5e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
JOAHLMEO_02215 9.8e-155 hbdA 1.1.1.157 I Dehydrogenase
JOAHLMEO_02216 8.2e-210 mmgC I acyl-CoA dehydrogenase
JOAHLMEO_02217 4.9e-207 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
JOAHLMEO_02218 6.3e-276 prpD 4.2.1.79 S 2-methylcitrate dehydratase
JOAHLMEO_02219 1.1e-159 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JOAHLMEO_02220 4e-34 yqzF S Protein of unknown function (DUF2627)
JOAHLMEO_02221 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
JOAHLMEO_02222 1e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
JOAHLMEO_02223 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
JOAHLMEO_02224 2.7e-202 buk 2.7.2.7 C Belongs to the acetokinase family
JOAHLMEO_02225 1.3e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
JOAHLMEO_02226 4.7e-185 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
JOAHLMEO_02227 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
JOAHLMEO_02228 2.6e-220 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
JOAHLMEO_02229 5.8e-152 bmrR K helix_turn_helix, mercury resistance
JOAHLMEO_02230 5.1e-207 norA EGP Major facilitator Superfamily
JOAHLMEO_02231 1.7e-165 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
JOAHLMEO_02232 9.3e-77 yqiW S Belongs to the UPF0403 family
JOAHLMEO_02233 4.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
JOAHLMEO_02234 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
JOAHLMEO_02235 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
JOAHLMEO_02236 1.2e-172 yqjA S Putative aromatic acid exporter C-terminal domain
JOAHLMEO_02237 3.4e-97 yqjB S protein conserved in bacteria
JOAHLMEO_02239 3e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
JOAHLMEO_02240 4.5e-288 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
JOAHLMEO_02241 6.2e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
JOAHLMEO_02242 2.7e-137 yqjF S Uncharacterized conserved protein (COG2071)
JOAHLMEO_02243 5.5e-139 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JOAHLMEO_02244 3.4e-24 yqzJ
JOAHLMEO_02245 1.8e-234 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JOAHLMEO_02246 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JOAHLMEO_02247 5.2e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JOAHLMEO_02248 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
JOAHLMEO_02249 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
JOAHLMEO_02250 1.1e-144 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
JOAHLMEO_02251 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
JOAHLMEO_02252 0.0 rocB E arginine degradation protein
JOAHLMEO_02253 1.5e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JOAHLMEO_02254 8.3e-179 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
JOAHLMEO_02255 7.8e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
JOAHLMEO_02256 4.6e-260 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
JOAHLMEO_02257 1.2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
JOAHLMEO_02258 5.7e-70 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JOAHLMEO_02260 1.1e-220 yqjV G Major Facilitator Superfamily
JOAHLMEO_02262 2.9e-237 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JOAHLMEO_02263 2.2e-49 S YolD-like protein
JOAHLMEO_02264 1.1e-86 yqjY K acetyltransferase
JOAHLMEO_02265 2e-58 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
JOAHLMEO_02266 1.3e-193 yqkA K GrpB protein
JOAHLMEO_02267 2.8e-54 yqkB S Belongs to the HesB IscA family
JOAHLMEO_02268 9.4e-39 yqkC S Protein of unknown function (DUF2552)
JOAHLMEO_02269 1.9e-172 yqkD S COG1073 Hydrolases of the alpha beta superfamily
JOAHLMEO_02270 1.3e-10 yqkE S Protein of unknown function (DUF3886)
JOAHLMEO_02271 1.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
JOAHLMEO_02273 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
JOAHLMEO_02274 5.1e-223 yqxK 3.6.4.12 L DNA helicase
JOAHLMEO_02275 4.5e-58 ansR K Transcriptional regulator
JOAHLMEO_02276 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
JOAHLMEO_02277 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
JOAHLMEO_02278 1.1e-227 mleN C Na H antiporter
JOAHLMEO_02279 5.5e-242 mleA 1.1.1.38 C malic enzyme
JOAHLMEO_02280 1.2e-29 yqkK
JOAHLMEO_02281 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
JOAHLMEO_02282 2.4e-80 fur P Belongs to the Fur family
JOAHLMEO_02283 3.7e-37 S Protein of unknown function (DUF4227)
JOAHLMEO_02284 2.6e-166 xerD L recombinase XerD
JOAHLMEO_02285 3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
JOAHLMEO_02286 2.9e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JOAHLMEO_02287 3.4e-211 dacF 3.4.16.4 M Belongs to the peptidase S11 family
JOAHLMEO_02288 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
JOAHLMEO_02289 2.3e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
JOAHLMEO_02290 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JOAHLMEO_02291 9.6e-112 spoVAA S Stage V sporulation protein AA
JOAHLMEO_02292 1e-67 spoVAB S Stage V sporulation protein AB
JOAHLMEO_02293 2.3e-78 spoVAC S stage V sporulation protein AC
JOAHLMEO_02294 6.5e-16 S Small spore protein J (Spore_SspJ)
JOAHLMEO_02295 4.1e-235 yvsH E Arginine ornithine antiporter
JOAHLMEO_02296 8.5e-176 fhuD P ABC transporter
JOAHLMEO_02297 3e-182 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOAHLMEO_02298 6.9e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOAHLMEO_02299 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
JOAHLMEO_02300 2e-174 M Efflux transporter rnd family, mfp subunit
JOAHLMEO_02301 2.1e-123 macB V ABC transporter, ATP-binding protein
JOAHLMEO_02302 4e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
JOAHLMEO_02303 3.8e-64 yvrL S Regulatory protein YrvL
JOAHLMEO_02304 8.1e-229 oxdC 4.1.1.2 G Oxalate decarboxylase
JOAHLMEO_02305 2.4e-19 S YvrJ protein family
JOAHLMEO_02306 9.5e-98 yvrI K RNA polymerase
JOAHLMEO_02307 7.2e-23
JOAHLMEO_02308 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JOAHLMEO_02309 0.0 T PhoQ Sensor
JOAHLMEO_02310 2.2e-170 yvrE G SMP-30/Gluconolaconase/LRE-like region
JOAHLMEO_02311 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JOAHLMEO_02312 1e-168 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
JOAHLMEO_02313 7.7e-186 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOAHLMEO_02314 1.4e-245 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
JOAHLMEO_02315 1.4e-99 yvqK 2.5.1.17 S Adenosyltransferase
JOAHLMEO_02316 4.8e-227 yvqJ EGP Major facilitator Superfamily
JOAHLMEO_02317 6.2e-61 liaI S membrane
JOAHLMEO_02318 2.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
JOAHLMEO_02319 1.8e-119 liaG S Putative adhesin
JOAHLMEO_02320 5.6e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
JOAHLMEO_02321 7.9e-186 vraS 2.7.13.3 T Histidine kinase
JOAHLMEO_02322 6.6e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JOAHLMEO_02323 4.1e-185 gerAC S Spore germination B3/ GerAC like, C-terminal
JOAHLMEO_02324 4.2e-195 gerAB E Spore germination protein
JOAHLMEO_02325 1.2e-245 gerAA EG Spore germination protein
JOAHLMEO_02326 2.3e-24 S Protein of unknown function (DUF3970)
JOAHLMEO_02327 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
JOAHLMEO_02328 1.3e-157 yuxN K Transcriptional regulator
JOAHLMEO_02329 1.2e-160 cssS 2.7.13.3 T PhoQ Sensor
JOAHLMEO_02330 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
JOAHLMEO_02331 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
JOAHLMEO_02332 1.2e-84 gerD
JOAHLMEO_02333 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
JOAHLMEO_02334 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
JOAHLMEO_02335 9.7e-66 ybaK S Protein of unknown function (DUF2521)
JOAHLMEO_02336 4.1e-144 ybaJ Q Methyltransferase domain
JOAHLMEO_02337 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
JOAHLMEO_02338 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JOAHLMEO_02339 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
JOAHLMEO_02340 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JOAHLMEO_02341 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JOAHLMEO_02342 5.6e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JOAHLMEO_02343 3.6e-58 rplQ J Ribosomal protein L17
JOAHLMEO_02344 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JOAHLMEO_02345 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JOAHLMEO_02346 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JOAHLMEO_02347 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
JOAHLMEO_02348 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JOAHLMEO_02349 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
JOAHLMEO_02350 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
JOAHLMEO_02351 5.5e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
JOAHLMEO_02352 1.8e-72 rplO J binds to the 23S rRNA
JOAHLMEO_02353 1.9e-23 rpmD J Ribosomal protein L30
JOAHLMEO_02354 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JOAHLMEO_02355 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JOAHLMEO_02356 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JOAHLMEO_02357 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JOAHLMEO_02358 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JOAHLMEO_02359 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JOAHLMEO_02360 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JOAHLMEO_02361 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JOAHLMEO_02362 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JOAHLMEO_02363 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
JOAHLMEO_02364 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JOAHLMEO_02365 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JOAHLMEO_02366 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JOAHLMEO_02367 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JOAHLMEO_02368 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JOAHLMEO_02369 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
JOAHLMEO_02370 3e-105 rplD J Forms part of the polypeptide exit tunnel
JOAHLMEO_02371 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JOAHLMEO_02372 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
JOAHLMEO_02373 4.5e-185 ybaC 3.4.11.5 S Alpha/beta hydrolase family
JOAHLMEO_02374 8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JOAHLMEO_02375 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JOAHLMEO_02376 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
JOAHLMEO_02377 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JOAHLMEO_02378 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
JOAHLMEO_02379 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JOAHLMEO_02380 9e-61 J tRNA cytidylyltransferase activity
JOAHLMEO_02381 2.6e-30 K Cro/C1-type HTH DNA-binding domain
JOAHLMEO_02382 4.7e-37 KLT RIO1 family
JOAHLMEO_02385 7.4e-121 isp O Subtilase family
JOAHLMEO_02386 6.8e-76
JOAHLMEO_02387 7.4e-23 1.15.1.2 C Rubrerythrin
JOAHLMEO_02389 6.9e-54 yoqW S Belongs to the SOS response-associated peptidase family
JOAHLMEO_02390 1.8e-95 S aspartate phosphatase
JOAHLMEO_02392 9e-19
JOAHLMEO_02393 4.4e-17 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
JOAHLMEO_02394 1e-99 yokH G SMI1 / KNR4 family
JOAHLMEO_02395 6.8e-278 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
JOAHLMEO_02396 4.2e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
JOAHLMEO_02397 1.1e-135 yobQ K helix_turn_helix, arabinose operon control protein
JOAHLMEO_02398 5.3e-141 yobR 2.3.1.1 J FR47-like protein
JOAHLMEO_02399 1.5e-95 yobS K Transcriptional regulator
JOAHLMEO_02400 7.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
JOAHLMEO_02401 3.2e-86 yobU K Bacterial transcription activator, effector binding domain
JOAHLMEO_02402 1.5e-172 yobV K WYL domain
JOAHLMEO_02403 2e-92 yobW
JOAHLMEO_02404 1e-51 czrA K transcriptional
JOAHLMEO_02405 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
JOAHLMEO_02406 1.5e-92 yozB S membrane
JOAHLMEO_02407 1.1e-144
JOAHLMEO_02408 1.5e-91 yocC
JOAHLMEO_02409 7.9e-185 yocD 3.4.17.13 V peptidase S66
JOAHLMEO_02410 1.2e-202 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
JOAHLMEO_02411 7.1e-198 desK 2.7.13.3 T Histidine kinase
JOAHLMEO_02412 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JOAHLMEO_02413 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
JOAHLMEO_02414 0.0 recQ 3.6.4.12 L DNA helicase
JOAHLMEO_02415 2.3e-113 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JOAHLMEO_02416 3.3e-83 dksA T general stress protein
JOAHLMEO_02417 5.4e-53 yocL
JOAHLMEO_02418 6.2e-32
JOAHLMEO_02419 3e-50 yocM O Belongs to the small heat shock protein (HSP20) family
JOAHLMEO_02420 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
JOAHLMEO_02422 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
JOAHLMEO_02423 1.8e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JOAHLMEO_02424 6.3e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
JOAHLMEO_02425 1.3e-185 ptxS K transcriptional
JOAHLMEO_02426 8.4e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
JOAHLMEO_02427 1.7e-102 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
JOAHLMEO_02428 5.6e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
JOAHLMEO_02429 1.1e-291 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
JOAHLMEO_02430 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
JOAHLMEO_02431 1e-224 pbuX F xanthine
JOAHLMEO_02432 7.7e-205 bcsA Q Naringenin-chalcone synthase
JOAHLMEO_02433 5.1e-87 ypbQ S protein conserved in bacteria
JOAHLMEO_02434 0.0 ypbR S Dynamin family
JOAHLMEO_02435 1e-38 ypbS S Protein of unknown function (DUF2533)
JOAHLMEO_02436 2e-07
JOAHLMEO_02437 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
JOAHLMEO_02439 2.1e-67 rnhA 3.1.26.4 L Ribonuclease
JOAHLMEO_02440 1e-105 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JOAHLMEO_02441 4.7e-135 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
JOAHLMEO_02442 3e-29 ypeQ S Zinc-finger
JOAHLMEO_02443 8.1e-31 S Protein of unknown function (DUF2564)
JOAHLMEO_02444 3.8e-16 degR
JOAHLMEO_02445 7.9e-31 cspD K Cold-shock protein
JOAHLMEO_02446 5.9e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
JOAHLMEO_02448 8.1e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JOAHLMEO_02449 1.1e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
JOAHLMEO_02450 1.3e-103 ypgQ S phosphohydrolase
JOAHLMEO_02451 5.8e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
JOAHLMEO_02452 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
JOAHLMEO_02453 7e-45 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JOAHLMEO_02454 4.3e-138 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
JOAHLMEO_02455 5.3e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
JOAHLMEO_02456 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
JOAHLMEO_02457 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
JOAHLMEO_02458 2.8e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JOAHLMEO_02459 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
JOAHLMEO_02460 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
JOAHLMEO_02461 1.1e-19 yxzF
JOAHLMEO_02462 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
JOAHLMEO_02463 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
JOAHLMEO_02464 7.3e-209 yxlH EGP Major facilitator Superfamily
JOAHLMEO_02465 1.2e-138 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
JOAHLMEO_02466 4.8e-165 yxlF V ABC transporter, ATP-binding protein
JOAHLMEO_02467 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
JOAHLMEO_02468 1.4e-30
JOAHLMEO_02469 3.9e-48 yxlC S Family of unknown function (DUF5345)
JOAHLMEO_02470 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
JOAHLMEO_02471 1.1e-253 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
JOAHLMEO_02472 7e-158 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JOAHLMEO_02473 0.0 cydD V ATP-binding protein
JOAHLMEO_02474 1.4e-309 cydD V ATP-binding
JOAHLMEO_02475 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
JOAHLMEO_02476 1.4e-267 cydA 1.10.3.14 C oxidase, subunit
JOAHLMEO_02477 4.2e-229 cimH C COG3493 Na citrate symporter
JOAHLMEO_02478 9.4e-311 3.4.24.84 O Peptidase family M48
JOAHLMEO_02480 2.1e-154 yxkH G Polysaccharide deacetylase
JOAHLMEO_02481 5.9e-205 msmK P Belongs to the ABC transporter superfamily
JOAHLMEO_02482 4.7e-38 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
JOAHLMEO_02483 2.5e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
JOAHLMEO_02484 3.3e-74 yutE S Protein of unknown function DUF86
JOAHLMEO_02485 9.7e-48 yutD S protein conserved in bacteria
JOAHLMEO_02486 8.3e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
JOAHLMEO_02487 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JOAHLMEO_02488 8.4e-195 lytH M Peptidase, M23
JOAHLMEO_02489 3.2e-133 yunB S Sporulation protein YunB (Spo_YunB)
JOAHLMEO_02490 5.3e-47 yunC S Domain of unknown function (DUF1805)
JOAHLMEO_02491 4.9e-265 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
JOAHLMEO_02492 7.2e-139 yunE S membrane transporter protein
JOAHLMEO_02493 4.3e-171 yunF S Protein of unknown function DUF72
JOAHLMEO_02494 3.1e-59 yunG
JOAHLMEO_02495 4.7e-257 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
JOAHLMEO_02496 2.4e-300 pucR QT COG2508 Regulator of polyketide synthase expression
JOAHLMEO_02497 5.5e-229 pbuX F Permease family
JOAHLMEO_02498 1.9e-223 pbuX F xanthine
JOAHLMEO_02499 6e-277 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
JOAHLMEO_02500 3.2e-56 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
JOAHLMEO_02502 2.8e-96 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
JOAHLMEO_02503 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
JOAHLMEO_02504 5.2e-145 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
JOAHLMEO_02505 1.7e-108 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
JOAHLMEO_02506 8.8e-184 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JOAHLMEO_02507 1e-237 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
JOAHLMEO_02508 7.5e-233 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
JOAHLMEO_02509 1.2e-168 bsn L Ribonuclease
JOAHLMEO_02510 1.7e-204 msmX P Belongs to the ABC transporter superfamily
JOAHLMEO_02511 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JOAHLMEO_02512 2.4e-39 yabK S Peptide ABC transporter permease
JOAHLMEO_02513 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
JOAHLMEO_02514 8.7e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JOAHLMEO_02515 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JOAHLMEO_02516 1.9e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JOAHLMEO_02517 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
JOAHLMEO_02518 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
JOAHLMEO_02519 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
JOAHLMEO_02520 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JOAHLMEO_02521 7.8e-39 veg S protein conserved in bacteria
JOAHLMEO_02522 4.7e-136 yabG S peptidase
JOAHLMEO_02523 1.2e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
JOAHLMEO_02524 1.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JOAHLMEO_02525 2e-167 rpfB GH23 T protein conserved in bacteria
JOAHLMEO_02526 7.6e-143 tatD L hydrolase, TatD
JOAHLMEO_02527 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JOAHLMEO_02528 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
JOAHLMEO_02529 1.2e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JOAHLMEO_02530 1.5e-49 yazA L endonuclease containing a URI domain
JOAHLMEO_02531 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
JOAHLMEO_02532 4.8e-31 yabA L Involved in initiation control of chromosome replication
JOAHLMEO_02533 6.1e-146 yaaT S stage 0 sporulation protein
JOAHLMEO_02534 1.1e-181 holB 2.7.7.7 L DNA polymerase III
JOAHLMEO_02535 1.5e-71 yaaR S protein conserved in bacteria
JOAHLMEO_02536 2.2e-54 yaaQ S protein conserved in bacteria
JOAHLMEO_02537 2.4e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JOAHLMEO_02538 6e-274 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
JOAHLMEO_02539 9.9e-203 yaaN P Belongs to the TelA family
JOAHLMEO_02540 5.8e-101 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
JOAHLMEO_02541 3.4e-31 csfB S Inhibitor of sigma-G Gin
JOAHLMEO_02542 1.5e-104 iolF EGP Major facilitator Superfamily
JOAHLMEO_02543 2e-194 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
JOAHLMEO_02544 8.6e-167 iolH G Xylose isomerase-like TIM barrel
JOAHLMEO_02545 2.1e-138 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
JOAHLMEO_02546 2.3e-159 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
JOAHLMEO_02547 5.5e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JOAHLMEO_02548 2.9e-179 T PhoQ Sensor
JOAHLMEO_02549 2.6e-138 yxdL V ABC transporter, ATP-binding protein
JOAHLMEO_02550 0.0 yxdM V ABC transporter (permease)
JOAHLMEO_02551 1.5e-58 yxeA S Protein of unknown function (DUF1093)
JOAHLMEO_02552 5.6e-175 fhuD P ABC transporter
JOAHLMEO_02553 8.5e-69
JOAHLMEO_02554 5.6e-16 yxeD
JOAHLMEO_02555 1.3e-20 yxeE
JOAHLMEO_02558 6.2e-151 yidA S hydrolases of the HAD superfamily
JOAHLMEO_02559 7.7e-188 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
JOAHLMEO_02560 4.1e-253 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JOAHLMEO_02561 2.9e-90 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JOAHLMEO_02562 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
JOAHLMEO_02563 4.5e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
JOAHLMEO_02564 9.1e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
JOAHLMEO_02565 4e-212 yxeP 3.5.1.47 E hydrolase activity
JOAHLMEO_02566 3.6e-249 yxeQ S MmgE/PrpD family
JOAHLMEO_02567 8.6e-196 eutH E Ethanolamine utilisation protein, EutH
JOAHLMEO_02568 5.7e-152 yxxB S Domain of Unknown Function (DUF1206)
JOAHLMEO_02572 6.9e-68 V ATPases associated with a variety of cellular activities
JOAHLMEO_02574 7.7e-61
JOAHLMEO_02575 1e-102 vpr O Belongs to the peptidase S8 family
JOAHLMEO_02576 5.2e-184 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JOAHLMEO_02577 2.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
JOAHLMEO_02578 2.9e-202 rodA D Belongs to the SEDS family
JOAHLMEO_02579 5.2e-204 S Acetyltransferase
JOAHLMEO_02580 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
JOAHLMEO_02581 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
JOAHLMEO_02582 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
JOAHLMEO_02583 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JOAHLMEO_02584 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
JOAHLMEO_02585 1e-35 ywzA S membrane
JOAHLMEO_02586 1.5e-299 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
JOAHLMEO_02587 4.9e-226 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JOAHLMEO_02588 9.5e-60 gtcA S GtrA-like protein
JOAHLMEO_02589 1.1e-121 ywcC K transcriptional regulator
JOAHLMEO_02591 1.7e-48 ywcB S Protein of unknown function, DUF485
JOAHLMEO_02592 3.1e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JOAHLMEO_02593 7.9e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
JOAHLMEO_02594 1.9e-223 ywbN P Dyp-type peroxidase family protein
JOAHLMEO_02595 3.2e-185 ycdO P periplasmic lipoprotein involved in iron transport
JOAHLMEO_02596 1.2e-250 P COG0672 High-affinity Fe2 Pb2 permease
JOAHLMEO_02597 5.5e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
JOAHLMEO_02598 4e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JOAHLMEO_02599 4.3e-153 ywbI K Transcriptional regulator
JOAHLMEO_02600 1.1e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
JOAHLMEO_02601 4e-111 ywbG M effector of murein hydrolase
JOAHLMEO_02602 2.9e-205 ywbF EGP Major facilitator Superfamily
JOAHLMEO_02603 6.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
JOAHLMEO_02604 1.1e-59 ywbD 2.1.1.191 J Methyltransferase
JOAHLMEO_02605 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JOAHLMEO_02606 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
JOAHLMEO_02607 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JOAHLMEO_02608 1.9e-124 ymfM S protein conserved in bacteria
JOAHLMEO_02609 2.7e-143 ymfK S Protein of unknown function (DUF3388)
JOAHLMEO_02610 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
JOAHLMEO_02611 7.8e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
JOAHLMEO_02612 3.9e-240 ymfH S zinc protease
JOAHLMEO_02613 2.7e-233 ymfF S Peptidase M16
JOAHLMEO_02614 3.8e-205 ymfD EGP Major facilitator Superfamily
JOAHLMEO_02615 4e-133 ymfC K Transcriptional regulator
JOAHLMEO_02616 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
JOAHLMEO_02617 2.9e-31 S YlzJ-like protein
JOAHLMEO_02618 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
JOAHLMEO_02619 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JOAHLMEO_02620 3.4e-155 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JOAHLMEO_02621 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
JOAHLMEO_02622 4.1e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JOAHLMEO_02623 4.8e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
JOAHLMEO_02624 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
JOAHLMEO_02625 2.6e-42 ymxH S YlmC YmxH family
JOAHLMEO_02626 4.4e-233 pepR S Belongs to the peptidase M16 family
JOAHLMEO_02627 2.8e-179 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
JOAHLMEO_02628 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
JOAHLMEO_02629 2.6e-144 pyrP F Xanthine uracil
JOAHLMEO_02630 3.4e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
JOAHLMEO_02631 9.2e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
JOAHLMEO_02632 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
JOAHLMEO_02633 0.0 carB 6.3.5.5 F Belongs to the CarB family
JOAHLMEO_02634 1.3e-142 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
JOAHLMEO_02635 4.6e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
JOAHLMEO_02636 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
JOAHLMEO_02637 5.6e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JOAHLMEO_02639 7.7e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
JOAHLMEO_02640 4.1e-179 cysP P phosphate transporter
JOAHLMEO_02641 5e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
JOAHLMEO_02642 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
JOAHLMEO_02643 2.4e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
JOAHLMEO_02644 7.1e-144 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
JOAHLMEO_02645 8.2e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
JOAHLMEO_02646 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
JOAHLMEO_02647 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
JOAHLMEO_02648 2.4e-156 yloC S stress-induced protein
JOAHLMEO_02649 1.5e-40 ylzA S Belongs to the UPF0296 family
JOAHLMEO_02650 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
JOAHLMEO_02651 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
JOAHLMEO_02652 1.4e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JOAHLMEO_02653 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JOAHLMEO_02654 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
JOAHLMEO_02655 8e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JOAHLMEO_02656 1.9e-250 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JOAHLMEO_02657 5.3e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
JOAHLMEO_02658 1.6e-140 stp 3.1.3.16 T phosphatase
JOAHLMEO_02659 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
JOAHLMEO_02660 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
JOAHLMEO_02661 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
JOAHLMEO_02662 1e-119 thiN 2.7.6.2 H thiamine pyrophosphokinase
JOAHLMEO_02663 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
JOAHLMEO_02664 5.5e-59 asp S protein conserved in bacteria
JOAHLMEO_02665 1.6e-299 yloV S kinase related to dihydroxyacetone kinase
JOAHLMEO_02666 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
JOAHLMEO_02667 1.6e-155 sdaAA 4.3.1.17 E L-serine dehydratase
JOAHLMEO_02668 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JOAHLMEO_02669 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
JOAHLMEO_02670 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
JOAHLMEO_02671 1e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
JOAHLMEO_02672 5.1e-128 IQ reductase
JOAHLMEO_02673 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
JOAHLMEO_02674 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
JOAHLMEO_02675 0.0 smc D Required for chromosome condensation and partitioning
JOAHLMEO_02676 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
JOAHLMEO_02677 2.9e-87
JOAHLMEO_02678 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JOAHLMEO_02679 1e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JOAHLMEO_02680 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
JOAHLMEO_02681 4.5e-36 ylqC S Belongs to the UPF0109 family
JOAHLMEO_02682 1.4e-60 ylqD S YlqD protein
JOAHLMEO_02683 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JOAHLMEO_02684 4.6e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
JOAHLMEO_02685 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
JOAHLMEO_02686 2.3e-156 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JOAHLMEO_02687 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JOAHLMEO_02688 1.1e-285 ylqG
JOAHLMEO_02689 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
JOAHLMEO_02690 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
JOAHLMEO_02691 3.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JOAHLMEO_02692 5.7e-166 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
JOAHLMEO_02693 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JOAHLMEO_02694 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JOAHLMEO_02695 2.5e-169 xerC L tyrosine recombinase XerC
JOAHLMEO_02696 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JOAHLMEO_02697 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JOAHLMEO_02698 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JOAHLMEO_02699 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
JOAHLMEO_02700 9.9e-74 flgC N Belongs to the flagella basal body rod proteins family
JOAHLMEO_02701 1.9e-31 fliE N Flagellar hook-basal body
JOAHLMEO_02702 2.4e-255 fliF N The M ring may be actively involved in energy transduction
JOAHLMEO_02703 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
JOAHLMEO_02704 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
JOAHLMEO_02705 1.6e-241 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
JOAHLMEO_02706 1.5e-69 fliJ N Flagellar biosynthesis chaperone
JOAHLMEO_02707 2.2e-36 ylxF S MgtE intracellular N domain
JOAHLMEO_02708 4.9e-215 fliK N Flagellar hook-length control protein
JOAHLMEO_02709 2.3e-72 flgD N Flagellar basal body rod modification protein
JOAHLMEO_02710 1.9e-136 flgG N Flagellar basal body rod
JOAHLMEO_02711 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
JOAHLMEO_02712 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
JOAHLMEO_02713 1e-183 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JOAHLMEO_02714 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
JOAHLMEO_02715 1.9e-94 fliZ N Flagellar biosynthesis protein, FliO
JOAHLMEO_02716 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
JOAHLMEO_02717 2.2e-36 fliQ N Role in flagellar biosynthesis
JOAHLMEO_02718 3.6e-132 fliR N Flagellar biosynthetic protein FliR
JOAHLMEO_02719 4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JOAHLMEO_02720 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JOAHLMEO_02721 5.7e-200 flhF N Flagellar biosynthesis regulator FlhF
JOAHLMEO_02722 1.7e-157 flhG D Belongs to the ParA family
JOAHLMEO_02723 2.2e-196 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
JOAHLMEO_02724 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
JOAHLMEO_02725 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
JOAHLMEO_02726 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
JOAHLMEO_02727 4.3e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
JOAHLMEO_02728 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JOAHLMEO_02729 5.3e-76 ylxL
JOAHLMEO_02730 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
JOAHLMEO_02731 4.1e-156 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JOAHLMEO_02732 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
JOAHLMEO_02733 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
JOAHLMEO_02734 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JOAHLMEO_02735 2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
JOAHLMEO_02736 1.7e-215 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
JOAHLMEO_02737 7.7e-233 rasP M zinc metalloprotease
JOAHLMEO_02738 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
JOAHLMEO_02739 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JOAHLMEO_02740 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
JOAHLMEO_02741 1.1e-203 nusA K Participates in both transcription termination and antitermination
JOAHLMEO_02742 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
JOAHLMEO_02743 3.1e-47 ylxQ J ribosomal protein
JOAHLMEO_02744 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JOAHLMEO_02745 3.9e-44 ylxP S protein conserved in bacteria
JOAHLMEO_02746 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JOAHLMEO_02747 5.6e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JOAHLMEO_02748 6.7e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
JOAHLMEO_02749 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JOAHLMEO_02750 1.9e-08 fliT S bacterial-type flagellum organization
JOAHLMEO_02751 6.5e-69 fliS N flagellar protein FliS
JOAHLMEO_02752 2e-256 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JOAHLMEO_02753 1.2e-55 flaG N flagellar protein FlaG
JOAHLMEO_02754 7.7e-80 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JOAHLMEO_02755 4.4e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
JOAHLMEO_02756 1.2e-71 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
JOAHLMEO_02757 4.8e-49 yviE
JOAHLMEO_02758 7.8e-155 flgL N Belongs to the bacterial flagellin family
JOAHLMEO_02759 2.5e-262 flgK N flagellar hook-associated protein
JOAHLMEO_02760 2.7e-77 flgN NOU FlgN protein
JOAHLMEO_02761 2.3e-38 flgM KNU Negative regulator of flagellin synthesis
JOAHLMEO_02762 2e-73 yvyF S flagellar protein
JOAHLMEO_02763 3.6e-126 comFC S Phosphoribosyl transferase domain
JOAHLMEO_02764 3.7e-45 comFB S Late competence development protein ComFB
JOAHLMEO_02765 9e-267 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JOAHLMEO_02766 2.1e-154 degV S protein conserved in bacteria
JOAHLMEO_02767 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JOAHLMEO_02768 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
JOAHLMEO_02769 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
JOAHLMEO_02770 6e-163 yvhJ K Transcriptional regulator
JOAHLMEO_02771 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
JOAHLMEO_02772 5.6e-233 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
JOAHLMEO_02773 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
JOAHLMEO_02774 1.5e-113 tuaF M protein involved in exopolysaccharide biosynthesis
JOAHLMEO_02775 3.5e-261 tuaE M Teichuronic acid biosynthesis protein
JOAHLMEO_02776 4.2e-256 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JOAHLMEO_02777 4e-220 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
JOAHLMEO_02778 4.4e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JOAHLMEO_02779 1.5e-92 tcyM U Binding-protein-dependent transport system inner membrane component
JOAHLMEO_02780 3.3e-141 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
JOAHLMEO_02781 9.9e-183 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JOAHLMEO_02782 1.2e-45 ytnI O COG0695 Glutaredoxin and related proteins
JOAHLMEO_02783 4.9e-254 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JOAHLMEO_02784 1.2e-126 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
JOAHLMEO_02785 8.7e-237 ytnL 3.5.1.47 E hydrolase activity
JOAHLMEO_02786 2.7e-155 ytnM S membrane transporter protein
JOAHLMEO_02787 8e-241 ytoI K transcriptional regulator containing CBS domains
JOAHLMEO_02788 2.4e-47 ytpI S YtpI-like protein
JOAHLMEO_02789 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
JOAHLMEO_02790 9.2e-29
JOAHLMEO_02791 8.2e-69 ytrI
JOAHLMEO_02792 3.2e-56 ytrH S Sporulation protein YtrH
JOAHLMEO_02793 0.0 dnaE 2.7.7.7 L DNA polymerase
JOAHLMEO_02794 3.4e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
JOAHLMEO_02795 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JOAHLMEO_02796 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
JOAHLMEO_02797 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
JOAHLMEO_02798 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
JOAHLMEO_02799 1.1e-62 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
JOAHLMEO_02800 3.4e-192 ytvI S sporulation integral membrane protein YtvI
JOAHLMEO_02801 4.7e-71 yeaL S membrane
JOAHLMEO_02802 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
JOAHLMEO_02803 4.1e-242 icd 1.1.1.42 C isocitrate
JOAHLMEO_02804 5.7e-54 K TipAS antibiotic-recognition domain
JOAHLMEO_02805 6.9e-123
JOAHLMEO_02806 2.3e-66 yybH S SnoaL-like domain
JOAHLMEO_02807 1.4e-121 yybG S Pentapeptide repeat-containing protein
JOAHLMEO_02808 2.3e-218 ynfM EGP Major facilitator Superfamily
JOAHLMEO_02809 4.5e-163 yybE K Transcriptional regulator
JOAHLMEO_02810 5e-78 yjcF S Acetyltransferase (GNAT) domain
JOAHLMEO_02811 1.6e-74 yybC
JOAHLMEO_02812 3.6e-125 S Metallo-beta-lactamase superfamily
JOAHLMEO_02813 5.6e-77 yybA 2.3.1.57 K transcriptional
JOAHLMEO_02814 7.6e-71 yjcF S Acetyltransferase (GNAT) domain
JOAHLMEO_02815 7.4e-93 yyaS S Membrane
JOAHLMEO_02817 2.6e-28 yyaL O Highly conserved protein containing a thioredoxin domain
JOAHLMEO_02818 1.8e-65 S Putative inner membrane exporter, YdcZ
JOAHLMEO_02819 9.7e-63 S Putative inner membrane exporter, YdcZ
JOAHLMEO_02820 9.1e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
JOAHLMEO_02821 5.1e-61 yyaN K MerR HTH family regulatory protein
JOAHLMEO_02822 1.2e-158 yyaM EG EamA-like transporter family
JOAHLMEO_02823 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
JOAHLMEO_02824 3.4e-166 yyaK S CAAX protease self-immunity
JOAHLMEO_02825 1.8e-243 EGP Major facilitator superfamily
JOAHLMEO_02826 2.8e-94 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
JOAHLMEO_02827 8.4e-66 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JOAHLMEO_02828 3.7e-176 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
JOAHLMEO_02829 5.8e-143 xth 3.1.11.2 L exodeoxyribonuclease III
JOAHLMEO_02830 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JOAHLMEO_02831 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
JOAHLMEO_02832 2.1e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
JOAHLMEO_02833 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
JOAHLMEO_02834 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JOAHLMEO_02835 2.9e-27 ywdA
JOAHLMEO_02836 1.7e-145 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
JOAHLMEO_02837 7.2e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
JOAHLMEO_02838 4.2e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JOAHLMEO_02839 2.7e-260 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
JOAHLMEO_02840 1.7e-48 ywdI S Family of unknown function (DUF5327)
JOAHLMEO_02841 4.6e-236 ywdJ F Xanthine uracil
JOAHLMEO_02842 4.3e-59 ywdK S small membrane protein
JOAHLMEO_02843 1.4e-74 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
JOAHLMEO_02844 6.9e-144 spsA M Spore Coat
JOAHLMEO_02845 3.1e-267 spsB M Capsule polysaccharide biosynthesis protein
JOAHLMEO_02846 6.7e-223 spsC E Belongs to the DegT DnrJ EryC1 family
JOAHLMEO_02847 5.8e-163 spsD 2.3.1.210 K Spore Coat
JOAHLMEO_02848 7.1e-214 spsE 2.5.1.56 M acid synthase
JOAHLMEO_02849 4.5e-129 spsF M Spore Coat
JOAHLMEO_02850 1.1e-184 spsG M Spore Coat
JOAHLMEO_02851 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JOAHLMEO_02852 8.7e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
JOAHLMEO_02853 5.8e-160 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
JOAHLMEO_02854 1.3e-86 spsL 5.1.3.13 M Spore Coat
JOAHLMEO_02855 1.2e-77
JOAHLMEO_02856 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
JOAHLMEO_02857 6e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
JOAHLMEO_02858 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
JOAHLMEO_02859 7.3e-155 yycI S protein conserved in bacteria
JOAHLMEO_02860 2.9e-257 yycH S protein conserved in bacteria
JOAHLMEO_02861 0.0 vicK 2.7.13.3 T Histidine kinase
JOAHLMEO_02862 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JOAHLMEO_02867 5.1e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JOAHLMEO_02868 2.6e-76 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JOAHLMEO_02869 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
JOAHLMEO_02870 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
JOAHLMEO_02872 1.9e-15 yycC K YycC-like protein
JOAHLMEO_02873 2.5e-220 yeaN P COG2807 Cyanate permease
JOAHLMEO_02874 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JOAHLMEO_02875 2.2e-73 rplI J binds to the 23S rRNA
JOAHLMEO_02876 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
JOAHLMEO_02877 1.9e-159 yybS S membrane
JOAHLMEO_02879 3.9e-84 cotF M Spore coat protein
JOAHLMEO_02880 1.7e-66 ydeP3 K Transcriptional regulator
JOAHLMEO_02881 3.3e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
JOAHLMEO_02882 5.6e-61
JOAHLMEO_02884 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
JOAHLMEO_02892 2e-08
JOAHLMEO_02896 1.7e-142 spo0M S COG4326 Sporulation control protein
JOAHLMEO_02897 4.4e-26
JOAHLMEO_02898 5e-133 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
JOAHLMEO_02899 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JOAHLMEO_02900 1.3e-262 ygaK C Berberine and berberine like
JOAHLMEO_02902 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
JOAHLMEO_02903 3.3e-138 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
JOAHLMEO_02904 4.3e-170 ssuA M Sulfonate ABC transporter
JOAHLMEO_02905 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
JOAHLMEO_02906 9e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
JOAHLMEO_02908 5e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JOAHLMEO_02909 2.6e-77 ygaO
JOAHLMEO_02910 4.4e-29 K Transcriptional regulator
JOAHLMEO_02912 8.7e-113 yhzB S B3/4 domain
JOAHLMEO_02913 6.6e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JOAHLMEO_02914 3.1e-175 yhbB S Putative amidase domain
JOAHLMEO_02915 9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
JOAHLMEO_02916 7.9e-109 yhbD K Protein of unknown function (DUF4004)
JOAHLMEO_02917 1e-64 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
JOAHLMEO_02918 3e-69 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
JOAHLMEO_02919 1.8e-23 ycsF S Belongs to the UPF0271 (lamB) family
JOAHLMEO_02920 2.1e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
JOAHLMEO_02921 4.8e-148 ycsI S Belongs to the D-glutamate cyclase family
JOAHLMEO_02922 3e-133 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
JOAHLMEO_02923 1.1e-184 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
JOAHLMEO_02924 2.7e-132 kipR K Transcriptional regulator
JOAHLMEO_02925 3.5e-117 ycsK E anatomical structure formation involved in morphogenesis
JOAHLMEO_02927 1.4e-49 yczJ S biosynthesis
JOAHLMEO_02928 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
JOAHLMEO_02929 8.1e-176 ydhF S Oxidoreductase
JOAHLMEO_02930 0.0 mtlR K transcriptional regulator, MtlR
JOAHLMEO_02931 2.3e-292 ydaB IQ acyl-CoA ligase
JOAHLMEO_02932 3.4e-98 ydaC Q Methyltransferase domain
JOAHLMEO_02933 4.1e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JOAHLMEO_02934 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
JOAHLMEO_02935 1.5e-100 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
JOAHLMEO_02936 6.8e-77 ydaG 1.4.3.5 S general stress protein
JOAHLMEO_02937 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
JOAHLMEO_02938 3.6e-45 ydzA EGP Major facilitator Superfamily
JOAHLMEO_02939 2.5e-74 lrpC K Transcriptional regulator
JOAHLMEO_02940 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JOAHLMEO_02941 2.1e-207 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
JOAHLMEO_02942 0.0 wapA M COG3209 Rhs family protein
JOAHLMEO_02945 1.3e-61 S Protein of unknown function (DUF2812)
JOAHLMEO_02946 5.5e-53 padR K Transcriptional regulator PadR-like family
JOAHLMEO_02947 2.5e-214 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
JOAHLMEO_02948 2.8e-263 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
JOAHLMEO_02949 7.3e-231 yxiO S COG2270 Permeases of the major facilitator superfamily
JOAHLMEO_02950 1.7e-93
JOAHLMEO_02951 3.1e-150 licT K transcriptional antiterminator
JOAHLMEO_02952 1.1e-143 exoK GH16 M licheninase activity
JOAHLMEO_02953 6.6e-224 citH C Citrate transporter
JOAHLMEO_02954 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
JOAHLMEO_02955 3e-47 yxiS
JOAHLMEO_02956 1.2e-104 T Domain of unknown function (DUF4163)
JOAHLMEO_02957 4.1e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JOAHLMEO_02958 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
JOAHLMEO_02959 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JOAHLMEO_02960 4.1e-30 yazB K transcriptional
JOAHLMEO_02961 7.4e-86 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JOAHLMEO_02962 3.8e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JOAHLMEO_02963 5.9e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JOAHLMEO_02964 8.7e-167 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
JOAHLMEO_02965 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
JOAHLMEO_02966 1.7e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JOAHLMEO_02967 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
JOAHLMEO_02968 8.5e-151 yacD 5.2.1.8 O peptidyl-prolyl isomerase
JOAHLMEO_02969 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JOAHLMEO_02970 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JOAHLMEO_02971 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JOAHLMEO_02972 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
JOAHLMEO_02973 1.9e-272 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
JOAHLMEO_02974 3.7e-185 KLT serine threonine protein kinase
JOAHLMEO_02975 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
JOAHLMEO_02976 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
JOAHLMEO_02979 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
JOAHLMEO_02980 1.1e-44 divIC D Septum formation initiator
JOAHLMEO_02981 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JOAHLMEO_02982 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JOAHLMEO_02983 1.8e-37 yaaB S Domain of unknown function (DUF370)
JOAHLMEO_02984 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JOAHLMEO_02985 2.4e-33 yaaA S S4 domain
JOAHLMEO_02986 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
JOAHLMEO_02987 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JOAHLMEO_02988 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
JOAHLMEO_02989 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JOAHLMEO_02990 6.5e-108 jag S single-stranded nucleic acid binding R3H
JOAHLMEO_02991 8.3e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JOAHLMEO_02992 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
JOAHLMEO_02993 7e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
JOAHLMEO_02994 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
JOAHLMEO_02995 8.2e-73 S Bacterial PH domain
JOAHLMEO_02996 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
JOAHLMEO_02997 2.1e-149 spo0J K Belongs to the ParB family
JOAHLMEO_02998 1.6e-111 yyaC S Sporulation protein YyaC
JOAHLMEO_02999 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JOAHLMEO_03000 5.3e-210 yjbB EGP Major Facilitator Superfamily
JOAHLMEO_03001 5.5e-172 oppF E Belongs to the ABC transporter superfamily
JOAHLMEO_03002 6.8e-198 oppD P Belongs to the ABC transporter superfamily
JOAHLMEO_03003 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JOAHLMEO_03004 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JOAHLMEO_03005 0.0 oppA E ABC transporter substrate-binding protein
JOAHLMEO_03006 2.3e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
JOAHLMEO_03007 1.9e-146 yjbA S Belongs to the UPF0736 family
JOAHLMEO_03008 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JOAHLMEO_03009 7.7e-169 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JOAHLMEO_03010 2.4e-287 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
JOAHLMEO_03011 3.6e-185 appF E Belongs to the ABC transporter superfamily
JOAHLMEO_03012 1.8e-184 appD P Belongs to the ABC transporter superfamily
JOAHLMEO_03013 1.6e-148 yjaZ O Zn-dependent protease
JOAHLMEO_03014 5.2e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
JOAHLMEO_03015 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JOAHLMEO_03016 5e-21 yjzB
JOAHLMEO_03017 7.3e-26 comZ S ComZ
JOAHLMEO_03018 2.5e-183 med S Transcriptional activator protein med
JOAHLMEO_03019 5.3e-101 yjaV
JOAHLMEO_03020 1.1e-141 yjaU I carboxylic ester hydrolase activity
JOAHLMEO_03021 2.3e-16 yjzD S Protein of unknown function (DUF2929)
JOAHLMEO_03022 9.5e-28 yjzC S YjzC-like protein
JOAHLMEO_03023 8.6e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JOAHLMEO_03024 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
JOAHLMEO_03025 7.4e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
JOAHLMEO_03026 7.8e-216 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
JOAHLMEO_03027 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
JOAHLMEO_03028 2.2e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JOAHLMEO_03029 4.7e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JOAHLMEO_03030 1.7e-88 norB G Major Facilitator Superfamily
JOAHLMEO_03031 9.8e-269 yitY C D-arabinono-1,4-lactone oxidase
JOAHLMEO_03032 1.5e-22 pilT S Proteolipid membrane potential modulator
JOAHLMEO_03033 1.4e-50 yitW S metal-sulfur cluster biosynthetic enzyme
JOAHLMEO_03034 1e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
JOAHLMEO_03035 1.9e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
JOAHLMEO_03037 1.2e-17 S Protein of unknown function (DUF3813)
JOAHLMEO_03038 5e-73 ipi S Intracellular proteinase inhibitor
JOAHLMEO_03039 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
JOAHLMEO_03040 9.3e-158 yitS S protein conserved in bacteria
JOAHLMEO_03041 3.2e-308 nprB 3.4.24.28 E Peptidase M4
JOAHLMEO_03042 1.4e-44 yitR S Domain of unknown function (DUF3784)
JOAHLMEO_03043 2.9e-94
JOAHLMEO_03044 1e-57 K Transcriptional regulator PadR-like family
JOAHLMEO_03045 1.5e-97 S Sporulation delaying protein SdpA
JOAHLMEO_03046 2.3e-170
JOAHLMEO_03047 8.5e-94
JOAHLMEO_03048 3.4e-160 cvfB S protein conserved in bacteria
JOAHLMEO_03049 1.9e-54 yajQ S Belongs to the UPF0234 family
JOAHLMEO_03050 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
JOAHLMEO_03051 1.6e-71 yjcF S Acetyltransferase (GNAT) domain
JOAHLMEO_03052 1.3e-156 yitH K Acetyltransferase (GNAT) domain
JOAHLMEO_03053 1.5e-228 yitG EGP Major facilitator Superfamily
JOAHLMEO_03054 1e-220 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
JOAHLMEO_03055 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
JOAHLMEO_03056 3.5e-140 yitD 4.4.1.19 S synthase
JOAHLMEO_03057 2.4e-119 comB 3.1.3.71 H Belongs to the ComB family
JOAHLMEO_03058 1.3e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
JOAHLMEO_03059 1.1e-228 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
JOAHLMEO_03060 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
JOAHLMEO_03061 2.7e-154 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
JOAHLMEO_03062 1.2e-35 mcbG S Pentapeptide repeats (9 copies)
JOAHLMEO_03063 2.3e-273 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JOAHLMEO_03064 3e-105 argO S Lysine exporter protein LysE YggA
JOAHLMEO_03065 1.8e-92 yisT S DinB family
JOAHLMEO_03066 8.8e-195 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
JOAHLMEO_03067 1.5e-183 purR K helix_turn _helix lactose operon repressor
JOAHLMEO_03068 1.2e-160 yisR K Transcriptional regulator
JOAHLMEO_03069 1.1e-240 yisQ V Mate efflux family protein
JOAHLMEO_03070 1.3e-116 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
JOAHLMEO_03071 0.0 asnO 6.3.5.4 E Asparagine synthase
JOAHLMEO_03072 2.2e-99 yisN S Protein of unknown function (DUF2777)
JOAHLMEO_03073 0.0 wprA O Belongs to the peptidase S8 family
JOAHLMEO_03074 3.9e-57 yisL S UPF0344 protein
JOAHLMEO_03075 2.1e-171 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
JOAHLMEO_03076 6.5e-173 cotH M Spore Coat
JOAHLMEO_03077 1.5e-22 yisI S Spo0E like sporulation regulatory protein
JOAHLMEO_03078 1.9e-33 gerPA S Spore germination protein
JOAHLMEO_03079 4e-34 gerPB S cell differentiation
JOAHLMEO_03080 5.3e-54 gerPC S Spore germination protein
JOAHLMEO_03081 1.1e-23 gerPD S Spore germination protein
JOAHLMEO_03082 5.3e-63 gerPE S Spore germination protein GerPE
JOAHLMEO_03083 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
JOAHLMEO_03084 1.1e-49 yisB V COG1403 Restriction endonuclease
JOAHLMEO_03085 0.0 sbcC L COG0419 ATPase involved in DNA repair
JOAHLMEO_03086 2e-219 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
JOAHLMEO_03087 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
JOAHLMEO_03088 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
JOAHLMEO_03089 6.4e-78 yhjR S Rubrerythrin
JOAHLMEO_03090 0.0 S Sugar transport-related sRNA regulator N-term
JOAHLMEO_03091 4.9e-213 EGP Transmembrane secretion effector
JOAHLMEO_03092 4.2e-201 abrB S membrane
JOAHLMEO_03093 4.5e-188 yhjM 5.1.1.1 K Transcriptional regulator
JOAHLMEO_03094 1.8e-253 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
JOAHLMEO_03095 5.8e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
JOAHLMEO_03096 2.7e-199 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
JOAHLMEO_03097 2.5e-212 glcP G Major Facilitator Superfamily
JOAHLMEO_03100 3.5e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
JOAHLMEO_03101 2.1e-277 yhjG CH FAD binding domain
JOAHLMEO_03102 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
JOAHLMEO_03103 9.1e-110 yhjE S SNARE associated Golgi protein
JOAHLMEO_03104 2.5e-59 yhjD
JOAHLMEO_03105 4.5e-26 yhjC S Protein of unknown function (DUF3311)
JOAHLMEO_03106 5.7e-264 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JOAHLMEO_03107 8.1e-39 yhjA S Excalibur calcium-binding domain
JOAHLMEO_03108 1.4e-167 IQ Enoyl-(Acyl carrier protein) reductase
JOAHLMEO_03109 4.2e-109 comK K Competence transcription factor
JOAHLMEO_03110 1.3e-32 yhzC S IDEAL
JOAHLMEO_03111 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JOAHLMEO_03112 4.4e-299 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
JOAHLMEO_03113 1.4e-181 hemAT NT chemotaxis protein
JOAHLMEO_03114 5e-91 bioY S BioY family
JOAHLMEO_03115 9.6e-272 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
JOAHLMEO_03116 6.5e-196 vraB 2.3.1.9 I Belongs to the thiolase family
JOAHLMEO_03117 2.1e-108 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
JOAHLMEO_03118 7.2e-75 yfmC M Periplasmic binding protein
JOAHLMEO_03119 1.4e-178 ytfP S HI0933-like protein
JOAHLMEO_03120 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
JOAHLMEO_03121 3.1e-26 yteV S Sporulation protein Cse60
JOAHLMEO_03122 5.3e-116 yteU S Integral membrane protein
JOAHLMEO_03123 1.3e-256 yteT S Oxidoreductase family, C-terminal alpha/beta domain
JOAHLMEO_03124 6.2e-70 yteS G transport
JOAHLMEO_03125 5.2e-217 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
JOAHLMEO_03126 7.5e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
JOAHLMEO_03127 0.0 ytdP K Transcriptional regulator
JOAHLMEO_03128 8.9e-289 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
JOAHLMEO_03129 2e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
JOAHLMEO_03130 2.8e-137 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
JOAHLMEO_03131 8.3e-221 bioI 1.14.14.46 C Cytochrome P450
JOAHLMEO_03132 1.2e-188 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JOAHLMEO_03133 1.7e-125 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JOAHLMEO_03134 4.5e-211 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
JOAHLMEO_03135 2.7e-260 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
JOAHLMEO_03136 4.4e-140 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
JOAHLMEO_03137 8e-145 ytaP S Acetyl xylan esterase (AXE1)
JOAHLMEO_03138 6.8e-08
JOAHLMEO_03139 9.9e-34
JOAHLMEO_03141 3.7e-34 S Bacterial protein of unknown function (DUF961)
JOAHLMEO_03143 7.9e-266 ydcQ D Ftsk spoiiie family protein
JOAHLMEO_03144 2.3e-198 nicK L Replication initiation factor
JOAHLMEO_03145 3.8e-34
JOAHLMEO_03148 3.3e-160 yddB S Conjugative transposon protein TcpC
JOAHLMEO_03149 3e-40 yddC
JOAHLMEO_03150 6.9e-95 yddD S TcpE family
JOAHLMEO_03151 0.0 yddE S AAA-like domain
JOAHLMEO_03152 1.3e-54 S Domain of unknown function (DUF1874)
JOAHLMEO_03153 0.0 yddG S maturation of SSU-rRNA
JOAHLMEO_03154 3.2e-186 yddH CBM50 M Lysozyme-like
JOAHLMEO_03155 1.3e-82 yddI
JOAHLMEO_03156 9.6e-62 S Domain of unknown function with cystatin-like fold (DUF4467)
JOAHLMEO_03157 2e-65 S Domain of unknown function (DUF1837)
JOAHLMEO_03158 5.6e-182 L DEAD-like helicases superfamily
JOAHLMEO_03159 5.6e-32 KLT Protein tyrosine kinase
JOAHLMEO_03160 7.6e-67 ywbC 4.4.1.5 E glyoxalase
JOAHLMEO_03161 1.8e-124 ywbB S Protein of unknown function (DUF2711)
JOAHLMEO_03162 3e-243 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JOAHLMEO_03163 6.4e-271 epr 3.4.21.62 O Belongs to the peptidase S8 family
JOAHLMEO_03164 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JOAHLMEO_03165 2e-152 sacY K transcriptional antiterminator
JOAHLMEO_03166 2.2e-167 gspA M General stress
JOAHLMEO_03167 3.7e-123 ywaF S Integral membrane protein
JOAHLMEO_03168 2.3e-87 ywaE K Transcriptional regulator
JOAHLMEO_03169 2.9e-232 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JOAHLMEO_03170 2.2e-249 ywaD 3.4.11.10, 3.4.11.6 S PA domain
JOAHLMEO_03171 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
JOAHLMEO_03172 3.5e-166 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
JOAHLMEO_03173 2.4e-289 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JOAHLMEO_03174 1.2e-232 dltB M membrane protein involved in D-alanine export
JOAHLMEO_03175 7.3e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JOAHLMEO_03176 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JOAHLMEO_03177 1.1e-09 S YyzF-like protein
JOAHLMEO_03178 5.7e-68
JOAHLMEO_03179 1.1e-233 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
JOAHLMEO_03181 2.8e-30 yycQ S Protein of unknown function (DUF2651)
JOAHLMEO_03182 3.5e-208 yycP
JOAHLMEO_03183 2.1e-129 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
JOAHLMEO_03184 1.1e-83 yycN 2.3.1.128 K Acetyltransferase
JOAHLMEO_03185 1.5e-187 S aspartate phosphatase
JOAHLMEO_03187 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
JOAHLMEO_03188 1.4e-254 rocE E amino acid
JOAHLMEO_03189 7.3e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
JOAHLMEO_03190 5.8e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
JOAHLMEO_03191 4.4e-171 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
JOAHLMEO_03192 1.5e-94 K PFAM response regulator receiver
JOAHLMEO_03193 8.8e-74 S Peptidase propeptide and YPEB domain
JOAHLMEO_03194 2.1e-16 S Peptidase propeptide and YPEB domain
JOAHLMEO_03195 4.9e-199 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JOAHLMEO_03196 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JOAHLMEO_03197 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
JOAHLMEO_03198 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JOAHLMEO_03199 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
JOAHLMEO_03200 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
JOAHLMEO_03201 4.4e-115 sigH K Belongs to the sigma-70 factor family
JOAHLMEO_03202 1.2e-88 yacP S RNA-binding protein containing a PIN domain
JOAHLMEO_03203 2.6e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JOAHLMEO_03204 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JOAHLMEO_03205 1.6e-271 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
JOAHLMEO_03206 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
JOAHLMEO_03207 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JOAHLMEO_03208 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
JOAHLMEO_03209 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
JOAHLMEO_03210 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
JOAHLMEO_03211 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
JOAHLMEO_03212 6.2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JOAHLMEO_03213 0.0 clpC O Belongs to the ClpA ClpB family
JOAHLMEO_03214 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
JOAHLMEO_03215 1.7e-57 mcsA 2.7.14.1 S protein with conserved CXXC pairs
JOAHLMEO_03216 2.9e-76 ctsR K Belongs to the CtsR family
JOAHLMEO_03217 4.3e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
JOAHLMEO_03218 7.3e-127 gntR K transcriptional
JOAHLMEO_03219 8.6e-303 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
JOAHLMEO_03220 3.8e-230 gntP EG COG2610 H gluconate symporter and related permeases
JOAHLMEO_03221 4.2e-272 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JOAHLMEO_03222 3.6e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
JOAHLMEO_03223 3.8e-287 ahpF O Alkyl hydroperoxide reductase
JOAHLMEO_03224 8.1e-188 wgaE S Polysaccharide pyruvyl transferase
JOAHLMEO_03225 2.4e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JOAHLMEO_03226 3.2e-25 bglF G phosphotransferase system
JOAHLMEO_03227 1.5e-18 bglF G phosphotransferase system
JOAHLMEO_03228 1.9e-124 yydK K Transcriptional regulator
JOAHLMEO_03229 7.6e-13
JOAHLMEO_03230 8.9e-117 S ABC-2 family transporter protein
JOAHLMEO_03231 1.6e-109 prrC P ABC transporter
JOAHLMEO_03232 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
JOAHLMEO_03233 7.4e-250 lysP E amino acid
JOAHLMEO_03234 6e-206 ywfA EGP Major facilitator Superfamily
JOAHLMEO_03235 7.3e-112 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
JOAHLMEO_03236 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
JOAHLMEO_03237 5.1e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JOAHLMEO_03238 3e-270 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
JOAHLMEO_03239 1.9e-209 bacE EGP Major facilitator Superfamily
JOAHLMEO_03240 1.5e-230 ywfG 2.6.1.83 E Aminotransferase class I and II
JOAHLMEO_03241 8.3e-137 IQ Enoyl-(Acyl carrier protein) reductase
JOAHLMEO_03242 3.3e-146 ywfI C May function as heme-dependent peroxidase
JOAHLMEO_03243 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
JOAHLMEO_03244 7.1e-156 cysL K Transcriptional regulator
JOAHLMEO_03245 8.7e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
JOAHLMEO_03246 2.2e-157 ywfM EG EamA-like transporter family
JOAHLMEO_03247 1e-110 rsfA_1
JOAHLMEO_03248 3.1e-36 ywzC S Belongs to the UPF0741 family
JOAHLMEO_03249 1.1e-255 ywfO S COG1078 HD superfamily phosphohydrolases
JOAHLMEO_03250 8.9e-79 T HPP family
JOAHLMEO_03251 1.5e-245 csbC EGP Major facilitator Superfamily
JOAHLMEO_03252 0.0 htpG O Molecular chaperone. Has ATPase activity
JOAHLMEO_03254 8.2e-151 IQ Enoyl-(Acyl carrier protein) reductase
JOAHLMEO_03255 6.2e-197 yxbF K Bacterial regulatory proteins, tetR family
JOAHLMEO_03256 1.7e-246 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
JOAHLMEO_03258 3.7e-91 S PQQ-like domain
JOAHLMEO_03259 1.1e-63 S Family of unknown function (DUF5391)
JOAHLMEO_03260 1.4e-75 yxaI S membrane protein domain
JOAHLMEO_03261 4.6e-227 P Protein of unknown function (DUF418)
JOAHLMEO_03262 6.4e-198 yxaG 1.13.11.24 S AraC-like ligand binding domain
JOAHLMEO_03263 2.7e-100 yxaF K Transcriptional regulator
JOAHLMEO_03264 1.2e-199 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JOAHLMEO_03265 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
JOAHLMEO_03266 5.2e-50 S LrgA family
JOAHLMEO_03267 3.4e-118 yxaC M effector of murein hydrolase
JOAHLMEO_03268 5e-90 yxaB GM Polysaccharide pyruvyl transferase
JOAHLMEO_03269 5.4e-101 yhgD K Transcriptional regulator
JOAHLMEO_03270 6.5e-265 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JOAHLMEO_03271 1.8e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
JOAHLMEO_03272 2.6e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JOAHLMEO_03273 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JOAHLMEO_03274 2.9e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
JOAHLMEO_03275 1.4e-15 1.15.1.2 C Rubrerythrin
JOAHLMEO_03276 1.6e-231 yhfA C membrane
JOAHLMEO_03277 2.8e-229 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
JOAHLMEO_03278 6.9e-114 ecsC S EcsC protein family
JOAHLMEO_03279 1.7e-213 ecsB U ABC transporter
JOAHLMEO_03280 4.6e-137 ecsA V transporter (ATP-binding protein)
JOAHLMEO_03281 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
JOAHLMEO_03282 2.4e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JOAHLMEO_03283 3.6e-80 trpP S Tryptophan transporter TrpP
JOAHLMEO_03284 5.4e-21
JOAHLMEO_03285 7e-39 yhaH S YtxH-like protein
JOAHLMEO_03286 3.3e-26
JOAHLMEO_03287 8e-28 KT COG4219 Antirepressor regulating drug resistance
JOAHLMEO_03288 7.4e-172 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
JOAHLMEO_03289 3.8e-114 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JOAHLMEO_03290 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JOAHLMEO_03291 1.3e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
JOAHLMEO_03292 4.4e-250 lysP E amino acid
JOAHLMEO_03293 1.7e-179 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
JOAHLMEO_03294 1.2e-233 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
JOAHLMEO_03295 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JOAHLMEO_03296 1.3e-282 hutH 4.3.1.3 E Histidine ammonia-lyase
JOAHLMEO_03297 1.9e-77 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
JOAHLMEO_03298 1.3e-276 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
JOAHLMEO_03299 6.9e-57 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
JOAHLMEO_03300 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
JOAHLMEO_03302 2.3e-173 S Patatin-like phospholipase
JOAHLMEO_03303 9.8e-93 yvdQ S Protein of unknown function (DUF3231)
JOAHLMEO_03304 7.1e-50 sugE P Small Multidrug Resistance protein
JOAHLMEO_03305 1.5e-50 ykkC P Small Multidrug Resistance protein
JOAHLMEO_03306 1.3e-105 yvdT K Transcriptional regulator
JOAHLMEO_03307 1.8e-295 yveA E amino acid
JOAHLMEO_03308 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
JOAHLMEO_03309 1.7e-273 sacB 2.4.1.10 GH68 M levansucrase activity
JOAHLMEO_03310 9.3e-66
JOAHLMEO_03311 5.1e-259 pbpE V Beta-lactamase
JOAHLMEO_03312 4e-127 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
JOAHLMEO_03313 2.1e-71 MA20_18690 S Protein of unknown function (DUF3237)
JOAHLMEO_03314 1.7e-92 padC Q Phenolic acid decarboxylase
JOAHLMEO_03315 8.2e-279 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
JOAHLMEO_03316 6.3e-76 slr K transcriptional
JOAHLMEO_03317 8.9e-122 ywqC M biosynthesis protein
JOAHLMEO_03318 6.6e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
JOAHLMEO_03319 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
JOAHLMEO_03320 2.5e-222 epsD GT4 M Glycosyl transferase 4-like
JOAHLMEO_03321 1.6e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
JOAHLMEO_03322 4.6e-216 epsF GT4 M Glycosyl transferases group 1
JOAHLMEO_03323 4.8e-207 epsG S EpsG family
JOAHLMEO_03324 6.4e-193 epsH GT2 S Glycosyltransferase like family 2
JOAHLMEO_03325 3.5e-202 epsI GM pyruvyl transferase
JOAHLMEO_03326 4.9e-193 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
JOAHLMEO_03327 2.7e-256 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JOAHLMEO_03328 5.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
JOAHLMEO_03329 2.6e-51 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
JOAHLMEO_03330 2.6e-219 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
JOAHLMEO_03331 2.3e-184 yvfF GM Exopolysaccharide biosynthesis protein
JOAHLMEO_03332 1e-31 yvfG S YvfG protein
JOAHLMEO_03333 5.2e-240 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
JOAHLMEO_03334 1.7e-307 yvfH C L-lactate permease
JOAHLMEO_03335 1e-112 yvfI K COG2186 Transcriptional regulators
JOAHLMEO_03336 1.8e-184 lacR K Transcriptional regulator
JOAHLMEO_03337 1.4e-229 cycB G COG2182 Maltose-binding periplasmic proteins domains
JOAHLMEO_03338 9.3e-231 malC P COG1175 ABC-type sugar transport systems, permease components
JOAHLMEO_03339 2.7e-149 ganQ P transport
JOAHLMEO_03340 0.0 lacA 3.2.1.23 G beta-galactosidase
JOAHLMEO_03341 1.2e-249 galA 3.2.1.89 G arabinogalactan
JOAHLMEO_03342 7.2e-196 rsbU 3.1.3.3 T response regulator
JOAHLMEO_03343 1.4e-155 rsbQ S Alpha/beta hydrolase family
JOAHLMEO_03344 2.4e-159 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
JOAHLMEO_03345 4e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
JOAHLMEO_03346 1.3e-194 desK 2.7.13.3 T Histidine kinase
JOAHLMEO_03347 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JOAHLMEO_03348 1e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
JOAHLMEO_03349 2.7e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
JOAHLMEO_03350 1.5e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
JOAHLMEO_03351 7.5e-194 yvbX S Glycosyl hydrolase
JOAHLMEO_03352 4.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
JOAHLMEO_03353 2.3e-154 yvbV EG EamA-like transporter family
JOAHLMEO_03354 5.1e-159 yvbU K Transcriptional regulator
JOAHLMEO_03355 4.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JOAHLMEO_03356 5.5e-203 araR K transcriptional
JOAHLMEO_03357 1.6e-252 araE EGP Major facilitator Superfamily
JOAHLMEO_03358 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
JOAHLMEO_03359 1.8e-184 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
JOAHLMEO_03360 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
JOAHLMEO_03361 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
JOAHLMEO_03362 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
JOAHLMEO_03363 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
JOAHLMEO_03364 8.8e-78 yvbK 3.1.3.25 K acetyltransferase
JOAHLMEO_03365 4.3e-253 tcaA S response to antibiotic
JOAHLMEO_03366 7.5e-121 exoY M Membrane
JOAHLMEO_03367 8.6e-113 yvbH S YvbH-like oligomerisation region
JOAHLMEO_03368 6.4e-103 yvbG U UPF0056 membrane protein
JOAHLMEO_03369 3.5e-97 yvbF K Belongs to the GbsR family
JOAHLMEO_03370 4.4e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
JOAHLMEO_03371 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
JOAHLMEO_03372 1.8e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
JOAHLMEO_03373 1.1e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
JOAHLMEO_03374 3.3e-60 yvbF K Belongs to the GbsR family
JOAHLMEO_03375 5.7e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
JOAHLMEO_03376 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
JOAHLMEO_03377 8e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
JOAHLMEO_03378 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
JOAHLMEO_03379 2e-63 NT chemotaxis protein
JOAHLMEO_03380 2.2e-54 yodB K transcriptional
JOAHLMEO_03381 9.8e-68 yvaO K Cro/C1-type HTH DNA-binding domain
JOAHLMEO_03382 1.2e-68 K transcriptional
JOAHLMEO_03383 9.8e-36 yvzC K Transcriptional
JOAHLMEO_03384 3.1e-152 yvaM S Serine aminopeptidase, S33
JOAHLMEO_03385 2.4e-23 secG U Preprotein translocase subunit SecG
JOAHLMEO_03386 5.6e-143 est 3.1.1.1 S Carboxylesterase
JOAHLMEO_03387 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
JOAHLMEO_03388 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JOAHLMEO_03390 2.6e-130 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JOAHLMEO_03391 1.3e-94 K Bacterial regulatory proteins, tetR family
JOAHLMEO_03392 5.3e-54 yvaE P Small Multidrug Resistance protein
JOAHLMEO_03393 9.7e-73 yvaD S Family of unknown function (DUF5360)
JOAHLMEO_03394 0.0 yvaC S Fusaric acid resistance protein-like
JOAHLMEO_03395 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JOAHLMEO_03396 2.8e-196 yvaA 1.1.1.371 S Oxidoreductase
JOAHLMEO_03397 2.2e-48 csoR S transcriptional
JOAHLMEO_03398 5.9e-29 copZ P Copper resistance protein CopZ
JOAHLMEO_03399 0.0 copA 3.6.3.54 P P-type ATPase
JOAHLMEO_03400 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
JOAHLMEO_03401 1.4e-103 bdbD O Thioredoxin
JOAHLMEO_03402 7.2e-71 bdbC O Required for disulfide bond formation in some proteins
JOAHLMEO_03403 1.6e-106 yvgT S membrane
JOAHLMEO_03405 0.0 helD 3.6.4.12 L DNA helicase
JOAHLMEO_03406 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JOAHLMEO_03407 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
JOAHLMEO_03408 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
JOAHLMEO_03409 2.1e-85 yvgO
JOAHLMEO_03410 5.9e-157 yvgN S reductase
JOAHLMEO_03411 4.9e-99 modB P COG4149 ABC-type molybdate transport system, permease component
JOAHLMEO_03412 7e-141 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
JOAHLMEO_03413 1e-211 pbuG S permease
JOAHLMEO_03414 8.9e-118 yebC M Membrane
JOAHLMEO_03416 8.9e-93 yebE S UPF0316 protein
JOAHLMEO_03417 8e-28 yebG S NETI protein
JOAHLMEO_03418 1.3e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JOAHLMEO_03419 1.3e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JOAHLMEO_03420 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JOAHLMEO_03421 1.4e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
JOAHLMEO_03422 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JOAHLMEO_03423 3.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JOAHLMEO_03424 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JOAHLMEO_03425 3.6e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JOAHLMEO_03426 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
JOAHLMEO_03427 2.4e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JOAHLMEO_03428 1e-181 yaaC S YaaC-like Protein
JOAHLMEO_03429 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
JOAHLMEO_03430 1.2e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
JOAHLMEO_03431 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JOAHLMEO_03432 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JOAHLMEO_03433 3.6e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JOAHLMEO_03434 1.3e-09
JOAHLMEO_03435 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
JOAHLMEO_03436 1e-113 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
JOAHLMEO_03437 1.2e-212 yaaH M Glycoside Hydrolase Family
JOAHLMEO_03438 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
JOAHLMEO_03439 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
JOAHLMEO_03440 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JOAHLMEO_03441 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JOAHLMEO_03442 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JOAHLMEO_03443 7.9e-32 yaaL S Protein of unknown function (DUF2508)
JOAHLMEO_03444 8.2e-36 bofA S Sigma-K factor-processing regulatory protein BofA
JOAHLMEO_03445 1.7e-25 S Tetratricopeptide repeat
JOAHLMEO_03449 1.5e-09 ywlA S Uncharacterised protein family (UPF0715)
JOAHLMEO_03455 6.2e-49 FG Scavenger mRNA decapping enzyme C-term binding
JOAHLMEO_03457 1.8e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
JOAHLMEO_03458 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
JOAHLMEO_03462 5.9e-166 bla 3.5.2.6 V beta-lactamase
JOAHLMEO_03463 8.6e-116 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
JOAHLMEO_03464 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
JOAHLMEO_03465 1.1e-144 tcyK M Bacterial periplasmic substrate-binding proteins
JOAHLMEO_03466 2.1e-151 tcyK ET Bacterial periplasmic substrate-binding proteins
JOAHLMEO_03467 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
JOAHLMEO_03468 1.9e-172 ytlI K LysR substrate binding domain
JOAHLMEO_03469 1.7e-130 ytkL S Belongs to the UPF0173 family
JOAHLMEO_03470 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JOAHLMEO_03472 7.5e-266 argH 4.3.2.1 E argininosuccinate lyase
JOAHLMEO_03473 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
JOAHLMEO_03474 1.4e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
JOAHLMEO_03475 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JOAHLMEO_03476 7e-165 ytxK 2.1.1.72 L DNA methylase
JOAHLMEO_03477 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JOAHLMEO_03478 8.7e-70 ytfJ S Sporulation protein YtfJ
JOAHLMEO_03479 2.1e-115 ytfI S Protein of unknown function (DUF2953)
JOAHLMEO_03480 8.5e-87 yteJ S RDD family
JOAHLMEO_03481 1.6e-21 sppA OU signal peptide peptidase SppA
JOAHLMEO_03482 7.7e-55 ytvB S Protein of unknown function (DUF4257)
JOAHLMEO_03483 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
JOAHLMEO_03484 3.9e-210 yttB EGP Major facilitator Superfamily
JOAHLMEO_03485 3.9e-43 yttA 2.7.13.3 S Pfam Transposase IS66
JOAHLMEO_03486 0.0 bceB V ABC transporter (permease)
JOAHLMEO_03487 7.3e-138 bceA V ABC transporter, ATP-binding protein
JOAHLMEO_03488 3.6e-185 T PhoQ Sensor
JOAHLMEO_03489 1.5e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JOAHLMEO_03490 2.3e-232 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
JOAHLMEO_03491 9.1e-127 ytrE V ABC transporter, ATP-binding protein
JOAHLMEO_03492 2.6e-148
JOAHLMEO_03493 6.1e-153 P ABC-2 family transporter protein
JOAHLMEO_03494 2.1e-160 ytrB P abc transporter atp-binding protein
JOAHLMEO_03495 7.6e-52 ytrA K GntR family transcriptional regulator
JOAHLMEO_03496 2.3e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
JOAHLMEO_03497 6.7e-184 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
JOAHLMEO_03498 4.8e-154 gltR1 K Transcriptional regulator
JOAHLMEO_03499 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
JOAHLMEO_03500 3e-34 yoeD G Helix-turn-helix domain
JOAHLMEO_03501 2.2e-96 L Integrase
JOAHLMEO_03503 3.1e-98 yoeB S IseA DL-endopeptidase inhibitor
JOAHLMEO_03504 2.3e-246 yoeA V MATE efflux family protein
JOAHLMEO_03505 1.4e-186 yoxA 5.1.3.3 G Aldose 1-epimerase
JOAHLMEO_03506 6.8e-273 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
JOAHLMEO_03507 1.9e-36 aprE 3.4.21.62 O Belongs to the peptidase S8 family
JOAHLMEO_03508 2.7e-241 yhfN 3.4.24.84 O Peptidase M48
JOAHLMEO_03509 1.3e-64 yhfM
JOAHLMEO_03510 1e-298 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
JOAHLMEO_03511 7.2e-110 yhfK GM NmrA-like family
JOAHLMEO_03512 2.2e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
JOAHLMEO_03513 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
JOAHLMEO_03514 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
JOAHLMEO_03515 1.1e-71 3.4.13.21 S ASCH
JOAHLMEO_03516 2.3e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
JOAHLMEO_03517 1.1e-136 yhfC S Putative membrane peptidase family (DUF2324)
JOAHLMEO_03518 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JOAHLMEO_03519 2e-138 yhgE S YhgE Pip N-terminal domain protein
JOAHLMEO_03520 6.2e-79 yffB K Transcriptional regulator
JOAHLMEO_03521 5.2e-238 mmr U Major Facilitator Superfamily
JOAHLMEO_03523 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JOAHLMEO_03524 3.3e-71 ywhA K Transcriptional regulator
JOAHLMEO_03525 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
JOAHLMEO_03526 5.1e-119 ywhC S Peptidase family M50
JOAHLMEO_03527 2e-94 ywhD S YwhD family
JOAHLMEO_03528 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JOAHLMEO_03529 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JOAHLMEO_03530 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
JOAHLMEO_03531 2.8e-28 ywhH S Aminoacyl-tRNA editing domain
JOAHLMEO_03533 7.5e-86 S aspartate phosphatase
JOAHLMEO_03534 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JOAHLMEO_03535 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JOAHLMEO_03536 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JOAHLMEO_03537 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
JOAHLMEO_03538 5.4e-110 ykoX S membrane-associated protein
JOAHLMEO_03539 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
JOAHLMEO_03540 1e-159 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
JOAHLMEO_03541 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
JOAHLMEO_03542 8.2e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
JOAHLMEO_03543 0.0 ykoS
JOAHLMEO_03544 2.1e-154 ykoQ S Calcineurin-like phosphoesterase superfamily domain
JOAHLMEO_03545 3.7e-99 ykoP G polysaccharide deacetylase
JOAHLMEO_03546 2.2e-57 spoVAEB S stage V sporulation protein
JOAHLMEO_03547 3.1e-110 spoVAEA S stage V sporulation protein
JOAHLMEO_03548 1.4e-273 spoVAF EG Stage V sporulation protein AF
JOAHLMEO_03549 3.4e-255 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
JOAHLMEO_03550 3.6e-149 ypuA S Secreted protein
JOAHLMEO_03551 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JOAHLMEO_03554 3.1e-16 S SNARE associated Golgi protein
JOAHLMEO_03555 6.6e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
JOAHLMEO_03556 1.4e-98 sipT 3.4.21.89 U Belongs to the peptidase S26 family
JOAHLMEO_03557 7.8e-55 ypuD
JOAHLMEO_03558 1.1e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JOAHLMEO_03559 3.3e-115 ribE 2.5.1.9 H Riboflavin synthase
JOAHLMEO_03560 2.9e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JOAHLMEO_03561 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
JOAHLMEO_03562 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JOAHLMEO_03563 2.3e-90 ypuF S Domain of unknown function (DUF309)
JOAHLMEO_03564 4.9e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JOAHLMEO_03565 5.4e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JOAHLMEO_03566 4e-98 ypuI S Protein of unknown function (DUF3907)
JOAHLMEO_03567 4.7e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
JOAHLMEO_03568 3.5e-103 spmA S Spore maturation protein
JOAHLMEO_03569 1.9e-87 spmB S Spore maturation protein
JOAHLMEO_03570 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
JOAHLMEO_03571 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
JOAHLMEO_03572 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
JOAHLMEO_03573 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
JOAHLMEO_03574 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JOAHLMEO_03575 0.0 resE 2.7.13.3 T Histidine kinase
JOAHLMEO_03576 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
JOAHLMEO_03577 1.3e-196 rsiX
JOAHLMEO_03578 1e-131 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
JOAHLMEO_03579 7.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JOAHLMEO_03580 1e-83 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JOAHLMEO_03581 4.7e-41 fer C Ferredoxin
JOAHLMEO_03582 2.7e-199 ypbB 5.1.3.1 S protein conserved in bacteria
JOAHLMEO_03583 9.2e-286 recQ 3.6.4.12 L DNA helicase
JOAHLMEO_03584 1.1e-99 ypbD S metal-dependent membrane protease
JOAHLMEO_03585 8.6e-75 ypbE M Lysin motif
JOAHLMEO_03586 2.8e-81 ypbF S Protein of unknown function (DUF2663)
JOAHLMEO_03587 2e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
JOAHLMEO_03588 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
JOAHLMEO_03589 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
JOAHLMEO_03590 6.2e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
JOAHLMEO_03591 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
JOAHLMEO_03592 3.3e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
JOAHLMEO_03593 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
JOAHLMEO_03594 3.9e-111 ypfA M Flagellar protein YcgR
JOAHLMEO_03595 4.1e-23 S Family of unknown function (DUF5359)
JOAHLMEO_03596 6.1e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
JOAHLMEO_03597 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
JOAHLMEO_03598 7.2e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
JOAHLMEO_03599 1e-07 S YpzI-like protein
JOAHLMEO_03600 6.7e-102 yphA
JOAHLMEO_03601 3.3e-161 seaA S YIEGIA protein
JOAHLMEO_03602 2.1e-28 ypzH
JOAHLMEO_03603 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
JOAHLMEO_03604 5.6e-181 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
JOAHLMEO_03605 1.2e-18 yphE S Protein of unknown function (DUF2768)
JOAHLMEO_03606 6.6e-136 yphF
JOAHLMEO_03607 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JOAHLMEO_03608 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
JOAHLMEO_03609 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
JOAHLMEO_03610 5e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
JOAHLMEO_03611 1.3e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
JOAHLMEO_03612 7.2e-132 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
JOAHLMEO_03613 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
JOAHLMEO_03614 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
JOAHLMEO_03615 1.1e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
JOAHLMEO_03616 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JOAHLMEO_03617 2.2e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JOAHLMEO_03618 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
JOAHLMEO_03619 2.8e-293 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JOAHLMEO_03620 6.1e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JOAHLMEO_03621 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
JOAHLMEO_03622 3e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
JOAHLMEO_03623 1.3e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
JOAHLMEO_03624 2.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
JOAHLMEO_03625 1.4e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JOAHLMEO_03626 2.6e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
JOAHLMEO_03627 1.1e-234 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
JOAHLMEO_03628 5.9e-233 S COG0457 FOG TPR repeat
JOAHLMEO_03629 1.1e-98 ypiB S Belongs to the UPF0302 family
JOAHLMEO_03630 2.1e-76 ypiF S Protein of unknown function (DUF2487)
JOAHLMEO_03631 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
JOAHLMEO_03632 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
JOAHLMEO_03633 4.3e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
JOAHLMEO_03634 6.8e-99 ypjA S membrane
JOAHLMEO_03635 1e-142 ypjB S sporulation protein
JOAHLMEO_03636 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
JOAHLMEO_03637 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
JOAHLMEO_03638 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
JOAHLMEO_03639 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
JOAHLMEO_03640 1.7e-128 bshB1 S proteins, LmbE homologs
JOAHLMEO_03641 2.6e-208 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
JOAHLMEO_03642 3e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
JOAHLMEO_03643 4.3e-183 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
JOAHLMEO_03644 1.2e-149 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
JOAHLMEO_03645 4.7e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JOAHLMEO_03646 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JOAHLMEO_03647 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
JOAHLMEO_03648 6.7e-23 ypmA S Protein of unknown function (DUF4264)
JOAHLMEO_03649 2.2e-79 ypmB S protein conserved in bacteria
JOAHLMEO_03650 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
JOAHLMEO_03651 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
JOAHLMEO_03652 6.3e-128 dnaD L DNA replication protein DnaD
JOAHLMEO_03653 8.3e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JOAHLMEO_03654 1.8e-92 ypoC
JOAHLMEO_03655 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
JOAHLMEO_03656 4.6e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
JOAHLMEO_03657 1.8e-186 yppC S Protein of unknown function (DUF2515)
JOAHLMEO_03660 1.5e-11 yppE S Bacterial domain of unknown function (DUF1798)
JOAHLMEO_03662 1e-47 yppG S YppG-like protein
JOAHLMEO_03663 5.6e-71 hspX O Belongs to the small heat shock protein (HSP20) family
JOAHLMEO_03664 3.3e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
JOAHLMEO_03665 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
JOAHLMEO_03666 5.6e-236 yprB L RNase_H superfamily
JOAHLMEO_03667 9.7e-92 ypsA S Belongs to the UPF0398 family
JOAHLMEO_03668 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
JOAHLMEO_03669 2.1e-67 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
JOAHLMEO_03670 5.6e-141 yvcR V ABC transporter, ATP-binding protein
JOAHLMEO_03671 0.0 yxdM V ABC transporter (permease)
JOAHLMEO_03672 2.5e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JOAHLMEO_03673 1.1e-104 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
JOAHLMEO_03674 2.8e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
JOAHLMEO_03675 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
JOAHLMEO_03676 8.1e-105 yvdD 3.2.2.10 S Belongs to the LOG family
JOAHLMEO_03677 5.1e-173 yvdE K Transcriptional regulator
JOAHLMEO_03678 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
JOAHLMEO_03679 4e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
JOAHLMEO_03681 5.4e-100 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
JOAHLMEO_03682 2.7e-88 M Glycosyltransferase like family 2
JOAHLMEO_03683 6.5e-215 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
JOAHLMEO_03684 2.7e-158 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
JOAHLMEO_03685 1e-11
JOAHLMEO_03686 0.0 lytB 3.5.1.28 D Stage II sporulation protein
JOAHLMEO_03687 3.5e-208 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
JOAHLMEO_03688 3.5e-112 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
JOAHLMEO_03689 9.6e-92 batE T Sh3 type 3 domain protein
JOAHLMEO_03690 8e-48 ywsA S Protein of unknown function (DUF3892)
JOAHLMEO_03691 1.3e-96 ywrO S NADPH-quinone reductase (modulator of drug activity B)
JOAHLMEO_03692 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
JOAHLMEO_03693 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
JOAHLMEO_03694 1.1e-169 alsR K LysR substrate binding domain
JOAHLMEO_03695 1.4e-218 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JOAHLMEO_03696 5.4e-124 ywrJ
JOAHLMEO_03697 1.8e-122 cotB
JOAHLMEO_03698 1.8e-206 cotH M Spore Coat
JOAHLMEO_03699 1.1e-12
JOAHLMEO_03700 2.2e-25 yfkQ EG Spore germination protein
JOAHLMEO_03701 1.1e-251 agcS_1 E Sodium alanine symporter
JOAHLMEO_03702 6e-67 yhdN S Domain of unknown function (DUF1992)
JOAHLMEO_03703 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
JOAHLMEO_03704 2e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
JOAHLMEO_03705 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
JOAHLMEO_03706 2.4e-50 yflH S Protein of unknown function (DUF3243)
JOAHLMEO_03707 4.1e-19 yflI
JOAHLMEO_03708 4e-18 yflJ S Protein of unknown function (DUF2639)
JOAHLMEO_03709 1.3e-122 yflK S protein conserved in bacteria
JOAHLMEO_03710 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
JOAHLMEO_03711 1.5e-216 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
JOAHLMEO_03712 1.3e-151 ydaK T Diguanylate cyclase, GGDEF domain
JOAHLMEO_03713 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
JOAHLMEO_03714 4.5e-233 ydaM M Glycosyl transferase family group 2
JOAHLMEO_03715 0.0 ydaN S Bacterial cellulose synthase subunit
JOAHLMEO_03716 0.0 ydaO E amino acid
JOAHLMEO_03717 3.6e-76 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
JOAHLMEO_03718 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
JOAHLMEO_03720 2.1e-39
JOAHLMEO_03721 2.5e-90 S CGNR zinc finger
JOAHLMEO_03722 8.3e-48 yxcD S Protein of unknown function (DUF2653)
JOAHLMEO_03724 3.2e-175 iolS C Aldo keto reductase
JOAHLMEO_03725 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
JOAHLMEO_03726 2e-280 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
JOAHLMEO_03727 3.3e-152 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
JOAHLMEO_03728 2.5e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
JOAHLMEO_03729 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
JOAHLMEO_03730 1.6e-171 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
JOAHLMEO_03731 1.1e-118 K Transcriptional regulator
JOAHLMEO_03732 7.2e-127 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
JOAHLMEO_03733 4.4e-99
JOAHLMEO_03735 8.2e-50
JOAHLMEO_03736 4.7e-48
JOAHLMEO_03737 3.7e-250 ywqJ S Pre-toxin TG
JOAHLMEO_03738 2e-37 ywqI S Family of unknown function (DUF5344)
JOAHLMEO_03739 7.7e-20 S Domain of unknown function (DUF5082)
JOAHLMEO_03740 4.9e-153 ywqG S Domain of unknown function (DUF1963)
JOAHLMEO_03741 1.8e-245 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JOAHLMEO_03742 1.3e-137 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
JOAHLMEO_03743 1.6e-61 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
JOAHLMEO_03744 1.3e-32 ywzB S membrane
JOAHLMEO_03745 4.1e-86 ywmA
JOAHLMEO_03746 8.5e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
JOAHLMEO_03747 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JOAHLMEO_03748 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JOAHLMEO_03749 1e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JOAHLMEO_03750 5.9e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JOAHLMEO_03751 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JOAHLMEO_03752 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JOAHLMEO_03753 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
JOAHLMEO_03754 2.5e-62 atpI S ATP synthase
JOAHLMEO_03755 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JOAHLMEO_03756 8.4e-122 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JOAHLMEO_03757 2.3e-20 S Domain of unknown function (DUF5082)
JOAHLMEO_03758 1.4e-38 yxiC S Family of unknown function (DUF5344)
JOAHLMEO_03759 2.1e-211 S nuclease activity
JOAHLMEO_03760 4.1e-21 S Immunity protein 8
JOAHLMEO_03761 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JOAHLMEO_03762 4e-278 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JOAHLMEO_03763 5.4e-72 yxiE T Belongs to the universal stress protein A family
JOAHLMEO_03764 2.3e-165 yxxF EG EamA-like transporter family
JOAHLMEO_03765 2.2e-271 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
JOAHLMEO_03766 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
JOAHLMEO_03767 1.4e-73 yxkC S Domain of unknown function (DUF4352)
JOAHLMEO_03768 3.9e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
JOAHLMEO_03769 2e-77 S Protein of unknown function (DUF1453)
JOAHLMEO_03770 2e-190 yxjM T Signal transduction histidine kinase
JOAHLMEO_03771 3.4e-115 K helix_turn_helix, Lux Regulon
JOAHLMEO_03772 1e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
JOAHLMEO_03774 1.5e-103 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JOAHLMEO_03776 3.1e-107 tmrB S AAA domain
JOAHLMEO_03777 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
JOAHLMEO_03778 2.4e-112 ycgI S Domain of unknown function (DUF1989)
JOAHLMEO_03779 4e-248 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
JOAHLMEO_03780 8.4e-150 yqcI S YqcI/YcgG family
JOAHLMEO_03781 6.8e-113 ycgF E Lysine exporter protein LysE YggA
JOAHLMEO_03782 1.3e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
JOAHLMEO_03783 1.1e-262 mdr EGP Major facilitator Superfamily
JOAHLMEO_03784 8e-291 lctP C L-lactate permease
JOAHLMEO_03785 4.7e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
JOAHLMEO_03786 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
JOAHLMEO_03787 4.5e-80 ycgB
JOAHLMEO_03788 3.6e-255 ycgA S Membrane
JOAHLMEO_03789 4.7e-213 amhX S amidohydrolase
JOAHLMEO_03790 5.3e-164 opuAC E glycine betaine
JOAHLMEO_03791 1.3e-127 opuAB P glycine betaine
JOAHLMEO_03792 2.5e-228 proV 3.6.3.32 E glycine betaine
JOAHLMEO_03793 6.1e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
JOAHLMEO_03794 1.2e-200 yceJ EGP Uncharacterised MFS-type transporter YbfB
JOAHLMEO_03795 8.7e-218 naiP P Uncharacterised MFS-type transporter YbfB
JOAHLMEO_03796 2e-192 yceH P Belongs to the TelA family
JOAHLMEO_03797 0.0 yceG S Putative component of 'biosynthetic module'
JOAHLMEO_03798 6.3e-137 terC P Protein of unknown function (DUF475)
JOAHLMEO_03799 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
JOAHLMEO_03800 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
JOAHLMEO_03801 7.4e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
JOAHLMEO_03802 1.6e-185 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JOAHLMEO_03803 1.9e-134 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
JOAHLMEO_03804 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
JOAHLMEO_03805 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
JOAHLMEO_03806 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
JOAHLMEO_03807 6.8e-139 IQ Enoyl-(Acyl carrier protein) reductase
JOAHLMEO_03808 1.2e-173 S response regulator aspartate phosphatase
JOAHLMEO_03809 1.3e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
JOAHLMEO_03810 2.2e-255 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
JOAHLMEO_03811 1.7e-273 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
JOAHLMEO_03812 6.6e-177 ycdA S Domain of unknown function (DUF5105)
JOAHLMEO_03813 5e-173 yccK C Aldo keto reductase
JOAHLMEO_03814 6e-200 natB CP ABC-2 family transporter protein
JOAHLMEO_03815 2.9e-131 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
JOAHLMEO_03816 4.5e-126 lytR_2 T LytTr DNA-binding domain
JOAHLMEO_03817 2.9e-155 2.7.13.3 T GHKL domain
JOAHLMEO_03818 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
JOAHLMEO_03819 1e-55 S RDD family
JOAHLMEO_03820 7.3e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
JOAHLMEO_03821 5.3e-201 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
JOAHLMEO_03822 7.7e-100 yxaF K Transcriptional regulator
JOAHLMEO_03823 7.6e-229 lmrB EGP the major facilitator superfamily
JOAHLMEO_03824 9.5e-203 ycbU E Selenocysteine lyase
JOAHLMEO_03825 5.9e-120 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JOAHLMEO_03826 2.6e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JOAHLMEO_03827 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
JOAHLMEO_03828 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
JOAHLMEO_03829 6.2e-134 ycbR T vWA found in TerF C terminus
JOAHLMEO_03830 2.2e-78 sleB 3.5.1.28 M Cell wall
JOAHLMEO_03831 4.1e-52 ycbP S Protein of unknown function (DUF2512)
JOAHLMEO_03832 3.3e-113 S ABC-2 family transporter protein
JOAHLMEO_03833 5.9e-166 ycbN V ABC transporter, ATP-binding protein
JOAHLMEO_03834 2.9e-168 T PhoQ Sensor
JOAHLMEO_03835 1.9e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JOAHLMEO_03836 6e-129 eamA1 EG spore germination
JOAHLMEO_03837 2.2e-27 eamA1 EG spore germination
JOAHLMEO_03838 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
JOAHLMEO_03839 2.9e-173 ycbJ S Macrolide 2'-phosphotransferase
JOAHLMEO_03840 3.5e-296 garD 4.2.1.42, 4.2.1.7 G Altronate
JOAHLMEO_03841 2.1e-123 ycbG K FCD
JOAHLMEO_03842 1.5e-269 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
JOAHLMEO_03843 2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
JOAHLMEO_03844 3.1e-273 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
JOAHLMEO_03845 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
JOAHLMEO_03846 9e-170 glnL T Regulator
JOAHLMEO_03847 4.2e-229 phoQ 2.7.13.3 T Histidine kinase
JOAHLMEO_03848 2.9e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
JOAHLMEO_03849 4.8e-255 agcS E Sodium alanine symporter
JOAHLMEO_03850 2.4e-178 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
JOAHLMEO_03851 8.2e-260 mmuP E amino acid
JOAHLMEO_03852 4.6e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
JOAHLMEO_03854 4.9e-128 K UTRA
JOAHLMEO_03855 2e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
JOAHLMEO_03856 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JOAHLMEO_03857 1.1e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
JOAHLMEO_03858 3.3e-191 yceA S Belongs to the UPF0176 family
JOAHLMEO_03859 2.1e-252 S Erythromycin esterase
JOAHLMEO_03860 4.6e-45 ybfN
JOAHLMEO_03861 8.1e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
JOAHLMEO_03862 2.7e-85 ybfM S SNARE associated Golgi protein
JOAHLMEO_03863 9.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JOAHLMEO_03864 4.1e-164 S Alpha/beta hydrolase family
JOAHLMEO_03866 6.9e-178 mpr 3.4.21.19 M Belongs to the peptidase S1B family
JOAHLMEO_03867 2e-211 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
JOAHLMEO_03868 2.6e-144 msmR K AraC-like ligand binding domain
JOAHLMEO_03869 2.4e-159 ybfH EG EamA-like transporter family
JOAHLMEO_03870 0.0 ybfG M Domain of unknown function (DUF1906)
JOAHLMEO_03872 1.6e-222 ybfB G COG0477 Permeases of the major facilitator superfamily
JOAHLMEO_03873 8.2e-168 ybfA 3.4.15.5 K FR47-like protein
JOAHLMEO_03874 1.5e-34 S Protein of unknown function (DUF2651)
JOAHLMEO_03875 7.3e-258 glpT G -transporter
JOAHLMEO_03876 1.8e-164 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
JOAHLMEO_03877 6.1e-35 ybeC E amino acid
JOAHLMEO_03878 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JOAHLMEO_03879 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JOAHLMEO_03880 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
JOAHLMEO_03881 2.8e-64 yngL S Protein of unknown function (DUF1360)
JOAHLMEO_03882 4.6e-157 ydhU P Catalase
JOAHLMEO_03883 1.7e-212 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
JOAHLMEO_03884 1.7e-184 manA 5.3.1.8 G mannose-6-phosphate isomerase
JOAHLMEO_03885 5.2e-167 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
JOAHLMEO_03886 6.2e-131 ydhQ K UTRA
JOAHLMEO_03887 5.2e-283 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JOAHLMEO_03888 2.2e-238 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JOAHLMEO_03889 1.3e-49 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
JOAHLMEO_03890 1.2e-46 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
JOAHLMEO_03891 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
JOAHLMEO_03892 2.1e-51 ytwF P Sulfurtransferase
JOAHLMEO_03893 2.2e-251 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
JOAHLMEO_03894 4.4e-144 amyC P ABC transporter (permease)
JOAHLMEO_03895 6.2e-168 amyD P ABC transporter
JOAHLMEO_03896 7.5e-244 msmE G Bacterial extracellular solute-binding protein
JOAHLMEO_03897 5.6e-189 msmR K Transcriptional regulator
JOAHLMEO_03898 7.1e-158 rlmA 2.1.1.187 Q Methyltransferase domain
JOAHLMEO_03899 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
JOAHLMEO_03900 2e-129 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JOAHLMEO_03901 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
JOAHLMEO_03902 1.8e-136 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
JOAHLMEO_03903 2.2e-218 yxjG 2.1.1.14 E Methionine synthase
JOAHLMEO_03904 1.6e-218 yxjG 2.1.1.14 E Methionine synthase
JOAHLMEO_03905 1.7e-51 yxjI S LURP-one-related
JOAHLMEO_03906 5.4e-147 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JOAHLMEO_03907 0.0 ytcJ S amidohydrolase
JOAHLMEO_03908 8.6e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
JOAHLMEO_03909 2e-29 sspB S spore protein
JOAHLMEO_03910 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JOAHLMEO_03911 3.5e-208 iscS2 2.8.1.7 E Cysteine desulfurase
JOAHLMEO_03912 5.6e-197 ywhK CO amine dehydrogenase activity
JOAHLMEO_03913 1.4e-243 ywhL CO amine dehydrogenase activity
JOAHLMEO_03915 1.5e-247 L Peptidase, M16
JOAHLMEO_03916 3.6e-216 2.7.1.26, 2.7.7.2 L Peptidase, M16
JOAHLMEO_03917 7.2e-234 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
JOAHLMEO_03918 1.9e-49 cbiO V ABC transporter
JOAHLMEO_03919 1.6e-123 ftsE D cell division ATP-binding protein FtsE
JOAHLMEO_03920 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
JOAHLMEO_03921 9.3e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
JOAHLMEO_03922 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JOAHLMEO_03923 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
JOAHLMEO_03924 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JOAHLMEO_03925 4.6e-51
JOAHLMEO_03926 3.9e-254 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JOAHLMEO_03927 3.3e-138 focA P Formate/nitrite transporter
JOAHLMEO_03928 7e-150 sacT K transcriptional antiterminator
JOAHLMEO_03931 2e-244 malC P COG1175 ABC-type sugar transport systems, permease components
JOAHLMEO_03932 3.9e-148 malD P transport
JOAHLMEO_03933 1.1e-153 malA S Protein of unknown function (DUF1189)
JOAHLMEO_03934 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
JOAHLMEO_03935 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
JOAHLMEO_03936 6.7e-167 ygxA S Nucleotidyltransferase-like
JOAHLMEO_03937 9.5e-56 ygzB S UPF0295 protein
JOAHLMEO_03938 4e-80 perR P Belongs to the Fur family
JOAHLMEO_03939 8.2e-87 bcp 1.11.1.15 O Peroxiredoxin
JOAHLMEO_03940 7.6e-244 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
JOAHLMEO_03941 3.3e-179 ygaE S Membrane
JOAHLMEO_03942 1.8e-301 ygaD V ABC transporter
JOAHLMEO_03943 1.3e-104 ygaC J Belongs to the UPF0374 family
JOAHLMEO_03944 1.5e-37 ygaB S YgaB-like protein
JOAHLMEO_03945 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
JOAHLMEO_03946 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JOAHLMEO_03947 6.9e-36 yfhS
JOAHLMEO_03948 3.3e-210 mutY L A G-specific
JOAHLMEO_03949 1.2e-185 yfhP S membrane-bound metal-dependent
JOAHLMEO_03950 0.0 yfhO S Bacterial membrane protein YfhO
JOAHLMEO_03951 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
JOAHLMEO_03952 1.3e-170 yfhM S Alpha beta hydrolase
JOAHLMEO_03953 1e-47 yfhL S SdpI/YhfL protein family
JOAHLMEO_03954 1.2e-88 batE T Bacterial SH3 domain homologues
JOAHLMEO_03955 1.3e-44 yfhJ S WVELL protein
JOAHLMEO_03956 6.2e-20 sspK S reproduction
JOAHLMEO_03957 3.6e-208 yfhI EGP Major facilitator Superfamily
JOAHLMEO_03958 1.7e-51 yfhH S Protein of unknown function (DUF1811)
JOAHLMEO_03959 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
JOAHLMEO_03960 3.2e-172 yfhF S nucleoside-diphosphate sugar epimerase
JOAHLMEO_03962 4e-24 yfhD S YfhD-like protein
JOAHLMEO_03963 4.4e-106 yfhC C nitroreductase
JOAHLMEO_03964 1.1e-166 yfhB 5.3.3.17 S PhzF family
JOAHLMEO_03965 1.2e-170 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOAHLMEO_03966 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOAHLMEO_03967 5.7e-175 yfiY P ABC transporter substrate-binding protein
JOAHLMEO_03968 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JOAHLMEO_03969 4.9e-79 yfiV K transcriptional
JOAHLMEO_03970 2.9e-282 yfiU EGP Major facilitator Superfamily
JOAHLMEO_03971 2.4e-98 yfiT S Belongs to the metal hydrolase YfiT family
JOAHLMEO_03972 5.3e-218 yfiS EGP Major facilitator Superfamily
JOAHLMEO_03973 2e-109 yfiR K Transcriptional regulator
JOAHLMEO_03974 4.5e-197 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
JOAHLMEO_03975 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
JOAHLMEO_03976 8.3e-99 padR K transcriptional
JOAHLMEO_03977 1.4e-67 J Acetyltransferase (GNAT) domain
JOAHLMEO_03978 6.4e-202 V COG0842 ABC-type multidrug transport system, permease component
JOAHLMEO_03979 1.2e-203 V ABC-2 family transporter protein
JOAHLMEO_03980 7.1e-167 V ABC transporter, ATP-binding protein
JOAHLMEO_03981 1e-111 KT LuxR family transcriptional regulator
JOAHLMEO_03982 8.2e-192 yxjM T Histidine kinase
JOAHLMEO_03983 5.7e-230 S Oxidoreductase
JOAHLMEO_03984 1.4e-178 G Xylose isomerase
JOAHLMEO_03985 1.9e-08 iolT EGP Major facilitator Superfamily
JOAHLMEO_03986 7.9e-166 K AraC-like ligand binding domain
JOAHLMEO_03987 9.7e-163 yfiE 1.13.11.2 S glyoxalase
JOAHLMEO_03988 9.8e-65 mhqP S DoxX
JOAHLMEO_03989 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
JOAHLMEO_03990 5.4e-306 yfiB3 V ABC transporter
JOAHLMEO_03991 0.0 yobO M COG5434 Endopolygalacturonase
JOAHLMEO_03992 1.2e-294 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JOAHLMEO_03993 4.6e-140 glvR K Helix-turn-helix domain, rpiR family
JOAHLMEO_03994 4.9e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
JOAHLMEO_03995 2.6e-44 yfjA S Belongs to the WXG100 family
JOAHLMEO_03996 1.4e-170 yfjB
JOAHLMEO_03997 1.2e-124 yfjC
JOAHLMEO_03998 4e-85 S Family of unknown function (DUF5381)
JOAHLMEO_03999 5.2e-56 yfjF S UPF0060 membrane protein
JOAHLMEO_04000 1.3e-24 sspH S Belongs to the SspH family
JOAHLMEO_04001 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
JOAHLMEO_04002 1.2e-255 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
JOAHLMEO_04003 3.2e-196 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
JOAHLMEO_04004 1.5e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
JOAHLMEO_04005 4.4e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
JOAHLMEO_04006 1.7e-29 yfjL
JOAHLMEO_04007 9.6e-85 yfjM S Psort location Cytoplasmic, score
JOAHLMEO_04008 2.4e-189 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JOAHLMEO_04009 6.3e-42 S YfzA-like protein
JOAHLMEO_04010 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JOAHLMEO_04011 1.3e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JOAHLMEO_04012 1.7e-184 corA P Mediates influx of magnesium ions
JOAHLMEO_04013 1.6e-149 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
JOAHLMEO_04014 1.7e-153 pdaA G deacetylase
JOAHLMEO_04015 1.1e-26 yfjT
JOAHLMEO_04016 5.4e-222 yfkA S YfkB-like domain
JOAHLMEO_04017 1.3e-148 yfkC M Mechanosensitive ion channel
JOAHLMEO_04018 1.2e-146 yfkD S YfkD-like protein
JOAHLMEO_04019 6.1e-183 cax P COG0387 Ca2 H antiporter
JOAHLMEO_04020 4.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
JOAHLMEO_04021 5e-08
JOAHLMEO_04022 1.3e-143 yihY S Belongs to the UPF0761 family
JOAHLMEO_04023 4.1e-50 yfkI S gas vesicle protein
JOAHLMEO_04024 1.2e-82 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JOAHLMEO_04025 1.3e-28 yfkK S Belongs to the UPF0435 family
JOAHLMEO_04026 1.3e-205 ydiM EGP Major facilitator Superfamily
JOAHLMEO_04027 3.6e-88 yfkM 1.11.1.6, 3.5.1.124 S protease
JOAHLMEO_04028 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
JOAHLMEO_04029 1.1e-124 yfkO C nitroreductase
JOAHLMEO_04030 1.1e-132 treR K transcriptional
JOAHLMEO_04031 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
JOAHLMEO_04032 4.4e-74 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)