ORF_ID e_value Gene_name EC_number CAZy COGs Description
LEKHBMCO_00002 1.6e-197 dtpT U amino acid peptide transporter
LEKHBMCO_00003 1.1e-07
LEKHBMCO_00005 2.3e-89 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LEKHBMCO_00006 4.9e-96 gntR1 K UbiC transcription regulator-associated domain protein
LEKHBMCO_00007 2.5e-90 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
LEKHBMCO_00008 3.3e-243 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LEKHBMCO_00009 4e-129 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LEKHBMCO_00010 8.2e-251 yhgF K Tex-like protein N-terminal domain protein
LEKHBMCO_00011 7.2e-45 ydcK S Belongs to the SprT family
LEKHBMCO_00013 1.3e-115 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LEKHBMCO_00014 5.9e-129 mleP2 S Sodium Bile acid symporter family
LEKHBMCO_00015 4.9e-85 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LEKHBMCO_00016 1e-33 S Enterocin A Immunity
LEKHBMCO_00017 7.6e-223 pepC 3.4.22.40 E Peptidase C1-like family
LEKHBMCO_00018 4.3e-19 HA62_12640 S GCN5-related N-acetyl-transferase
LEKHBMCO_00019 4e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
LEKHBMCO_00020 1.1e-224 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LEKHBMCO_00021 8.2e-154 yacL S domain protein
LEKHBMCO_00022 1.4e-246 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LEKHBMCO_00023 1.8e-206 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
LEKHBMCO_00024 6.4e-56 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LEKHBMCO_00025 3.2e-109 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LEKHBMCO_00026 5.4e-71 yacP S YacP-like NYN domain
LEKHBMCO_00027 2.1e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
LEKHBMCO_00028 2.6e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LEKHBMCO_00029 7.7e-84 nusG K Participates in transcription elongation, termination and antitermination
LEKHBMCO_00030 5e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LEKHBMCO_00031 1.6e-115 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LEKHBMCO_00032 7.6e-75 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LEKHBMCO_00033 2.6e-48 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LEKHBMCO_00034 1.4e-54
LEKHBMCO_00035 2.1e-301 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LEKHBMCO_00036 1e-160 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LEKHBMCO_00037 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LEKHBMCO_00038 4.8e-45 nrdI F NrdI Flavodoxin like
LEKHBMCO_00039 1.2e-27 nrdH O Glutaredoxin
LEKHBMCO_00040 1.1e-75 rsmC 2.1.1.172 J Methyltransferase
LEKHBMCO_00041 3.3e-62 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LEKHBMCO_00042 1.3e-209 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LEKHBMCO_00043 1.4e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LEKHBMCO_00044 2.2e-97 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LEKHBMCO_00045 9.2e-29 yaaL S Protein of unknown function (DUF2508)
LEKHBMCO_00046 1.4e-65 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LEKHBMCO_00047 3.9e-83 holB 2.7.7.7 L DNA polymerase III
LEKHBMCO_00048 1.4e-40 yabA L Involved in initiation control of chromosome replication
LEKHBMCO_00049 2.4e-92 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LEKHBMCO_00050 4.7e-81 fat 3.1.2.21 I Acyl-ACP thioesterase
LEKHBMCO_00051 3.5e-140 ansA 3.5.1.1 EJ Asparaginase
LEKHBMCO_00052 3.7e-70 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
LEKHBMCO_00053 4.3e-28 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
LEKHBMCO_00054 8.4e-161 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LEKHBMCO_00055 3.4e-256 uup S ABC transporter, ATP-binding protein
LEKHBMCO_00056 2.8e-98 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LEKHBMCO_00057 1.4e-33 S CAAX protease self-immunity
LEKHBMCO_00058 2.4e-33 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LEKHBMCO_00059 1.3e-272 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LEKHBMCO_00060 2.5e-269 aha1 P COG COG0474 Cation transport ATPase
LEKHBMCO_00061 1.2e-295 ydaO E amino acid
LEKHBMCO_00062 1.6e-157 tagO 2.7.8.33, 2.7.8.35 M transferase
LEKHBMCO_00063 3.2e-128 comFA L Helicase C-terminal domain protein
LEKHBMCO_00064 5.6e-44 comFC S Competence protein
LEKHBMCO_00065 6e-81 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LEKHBMCO_00066 7e-95 yeaN P Major Facilitator Superfamily
LEKHBMCO_00067 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LEKHBMCO_00068 2.2e-164 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LEKHBMCO_00069 9.1e-68 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
LEKHBMCO_00070 6e-86 K response regulator
LEKHBMCO_00071 1.2e-85 phoR 2.7.13.3 T Histidine kinase
LEKHBMCO_00072 2.4e-08 pspC KT PspC domain
LEKHBMCO_00073 1.6e-26 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
LEKHBMCO_00074 8.7e-133 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LEKHBMCO_00075 1.1e-112 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LEKHBMCO_00076 6.1e-273 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
LEKHBMCO_00077 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LEKHBMCO_00078 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LEKHBMCO_00079 1.1e-83 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LEKHBMCO_00080 5e-79 ylbE GM NAD dependent epimerase dehydratase family protein
LEKHBMCO_00081 7.5e-126 rapZ S Displays ATPase and GTPase activities
LEKHBMCO_00082 8.2e-153 ybhK S Required for morphogenesis under gluconeogenic growth conditions
LEKHBMCO_00083 1.8e-149 whiA K May be required for sporulation
LEKHBMCO_00084 1.1e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LEKHBMCO_00086 1.1e-136 cggR K Putative sugar-binding domain
LEKHBMCO_00087 6.1e-180 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LEKHBMCO_00088 1.3e-208 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
LEKHBMCO_00089 2.3e-128 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LEKHBMCO_00090 9.5e-234 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LEKHBMCO_00091 2.2e-132 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LEKHBMCO_00092 5e-104 K response regulator
LEKHBMCO_00093 1.8e-169 T PhoQ Sensor
LEKHBMCO_00094 6.7e-146 lmrP E Major Facilitator Superfamily
LEKHBMCO_00095 1.2e-179 clcA P chloride
LEKHBMCO_00096 2.8e-19 secG U Preprotein translocase
LEKHBMCO_00097 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LEKHBMCO_00098 6.9e-70 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
LEKHBMCO_00099 9.1e-42 yxjI
LEKHBMCO_00100 2.4e-116 ycsE S Sucrose-6F-phosphate phosphohydrolase
LEKHBMCO_00101 5.2e-106 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LEKHBMCO_00102 2e-143 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
LEKHBMCO_00103 3.2e-56 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
LEKHBMCO_00104 1.9e-68 dnaQ 2.7.7.7 L DNA polymerase III
LEKHBMCO_00105 3.5e-115 murB 1.3.1.98 M Cell wall formation
LEKHBMCO_00106 2.4e-71 S Protein of unknown function (DUF1361)
LEKHBMCO_00107 8.5e-127 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LEKHBMCO_00108 5.3e-68 ybbR S YbbR-like protein
LEKHBMCO_00109 2.6e-226 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LEKHBMCO_00110 7.5e-29 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
LEKHBMCO_00111 5.3e-131 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
LEKHBMCO_00112 3.2e-21 cutC P Participates in the control of copper homeostasis
LEKHBMCO_00113 4e-197 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LEKHBMCO_00114 5.9e-164 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LEKHBMCO_00115 4.9e-61 ybaK J Aminoacyl-tRNA editing domain
LEKHBMCO_00116 1.7e-98 rrmA 2.1.1.187 H Methyltransferase
LEKHBMCO_00117 4.4e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LEKHBMCO_00118 1.6e-284 ftsK D Belongs to the FtsK SpoIIIE SftA family
LEKHBMCO_00119 3.5e-108 ymfF S Peptidase M16 inactive domain protein
LEKHBMCO_00120 3.9e-147 ymfH S Peptidase M16
LEKHBMCO_00121 8.4e-91 IQ Enoyl-(Acyl carrier protein) reductase
LEKHBMCO_00122 2.9e-64 ymfM S Helix-turn-helix domain
LEKHBMCO_00123 4.3e-85 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LEKHBMCO_00124 5.1e-159 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LEKHBMCO_00125 2.6e-182 rny S Endoribonuclease that initiates mRNA decay
LEKHBMCO_00126 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LEKHBMCO_00127 6e-224 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LEKHBMCO_00128 7.3e-72 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LEKHBMCO_00129 6.3e-153 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LEKHBMCO_00130 2.1e-183 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LEKHBMCO_00131 2.9e-207 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LEKHBMCO_00132 1.8e-12 yajC U Preprotein translocase
LEKHBMCO_00134 4.3e-61 uspA T universal stress protein
LEKHBMCO_00136 2e-208 yfnA E Amino Acid
LEKHBMCO_00137 6.9e-117 lutA C Cysteine-rich domain
LEKHBMCO_00138 3.1e-244 lutB C 4Fe-4S dicluster domain
LEKHBMCO_00139 1.9e-66 yrjD S LUD domain
LEKHBMCO_00140 1e-146 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LEKHBMCO_00141 7.5e-13
LEKHBMCO_00142 2.7e-121 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
LEKHBMCO_00143 3.9e-187 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LEKHBMCO_00144 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LEKHBMCO_00145 2.1e-36 yrzL S Belongs to the UPF0297 family
LEKHBMCO_00146 2.3e-59 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LEKHBMCO_00147 1.9e-33 yrzB S Belongs to the UPF0473 family
LEKHBMCO_00148 1.4e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LEKHBMCO_00149 9.5e-18 cvpA S Colicin V production protein
LEKHBMCO_00150 1.4e-309 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LEKHBMCO_00151 9.9e-41 trxA O Belongs to the thioredoxin family
LEKHBMCO_00152 2.4e-33 yslB S Protein of unknown function (DUF2507)
LEKHBMCO_00153 2.2e-73 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LEKHBMCO_00154 5.1e-42 S Phosphoesterase
LEKHBMCO_00157 1.2e-140 hprA 1.1.1.29 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEKHBMCO_00158 2.8e-305 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LEKHBMCO_00159 2.2e-214 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LEKHBMCO_00160 4.8e-199 oatA I Acyltransferase
LEKHBMCO_00161 1.4e-16
LEKHBMCO_00163 8.9e-141 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LEKHBMCO_00164 6.5e-100 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
LEKHBMCO_00165 5.2e-219 recJ L Single-stranded-DNA-specific exonuclease RecJ
LEKHBMCO_00166 1.3e-80 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LEKHBMCO_00167 1.2e-296 S membrane
LEKHBMCO_00168 1.5e-278 pbp2b 3.4.16.4 M Penicillin-binding Protein
LEKHBMCO_00169 1.8e-27 S Protein of unknown function (DUF3290)
LEKHBMCO_00170 3.3e-75 yviA S Protein of unknown function (DUF421)
LEKHBMCO_00172 4.5e-125 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
LEKHBMCO_00173 7.7e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
LEKHBMCO_00174 1.1e-53 tag 3.2.2.20 L glycosylase
LEKHBMCO_00175 6e-72 usp6 T universal stress protein
LEKHBMCO_00177 5.1e-184 rarA L recombination factor protein RarA
LEKHBMCO_00178 3.4e-24 yueI S Protein of unknown function (DUF1694)
LEKHBMCO_00179 7.5e-101 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LEKHBMCO_00180 4.2e-56 ytsP 1.8.4.14 T GAF domain-containing protein
LEKHBMCO_00181 5.8e-175 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LEKHBMCO_00182 6.4e-162 iscS2 2.8.1.7 E Aminotransferase class V
LEKHBMCO_00183 1.9e-196 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LEKHBMCO_00184 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LEKHBMCO_00185 3.7e-137 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
LEKHBMCO_00186 8.1e-80 radC L DNA repair protein
LEKHBMCO_00187 4.5e-21 K Cold shock
LEKHBMCO_00188 3.6e-156 mreB D cell shape determining protein MreB
LEKHBMCO_00189 2.1e-88 mreC M Involved in formation and maintenance of cell shape
LEKHBMCO_00190 2e-54 mreD M rod shape-determining protein MreD
LEKHBMCO_00191 8.3e-77 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
LEKHBMCO_00192 1.8e-126 minD D Belongs to the ParA family
LEKHBMCO_00193 1.9e-94 glnP P ABC transporter permease
LEKHBMCO_00194 1.8e-89 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
LEKHBMCO_00195 3.7e-109 aatB ET ABC transporter substrate-binding protein
LEKHBMCO_00196 9.8e-100 D Alpha beta
LEKHBMCO_00198 1.2e-155 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
LEKHBMCO_00199 2.9e-07 S Protein of unknown function (DUF3397)
LEKHBMCO_00200 1.5e-55 mraZ K Belongs to the MraZ family
LEKHBMCO_00201 8e-142 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LEKHBMCO_00202 2.5e-11 ftsL D cell division protein FtsL
LEKHBMCO_00203 4e-282 ftsI 3.4.16.4 M Penicillin-binding Protein
LEKHBMCO_00204 8.7e-136 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LEKHBMCO_00205 2.2e-185 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LEKHBMCO_00206 1.8e-153 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LEKHBMCO_00207 1.3e-61 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LEKHBMCO_00208 5.2e-190 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LEKHBMCO_00209 9.8e-180 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LEKHBMCO_00210 5e-33 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LEKHBMCO_00211 3e-19 yggT S YGGT family
LEKHBMCO_00212 1.7e-81 ylmH S S4 domain protein
LEKHBMCO_00213 8.6e-62 divIVA D DivIVA domain protein
LEKHBMCO_00214 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LEKHBMCO_00215 1.3e-58 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LEKHBMCO_00216 2.2e-29 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LEKHBMCO_00217 4.4e-74 draG O ADP-ribosylglycohydrolase
LEKHBMCO_00219 5.7e-85 2.7.7.12 C Domain of unknown function (DUF4931)
LEKHBMCO_00220 1.4e-92 T Calcineurin-like phosphoesterase superfamily domain
LEKHBMCO_00221 5.5e-49 lytE M LysM domain protein
LEKHBMCO_00222 5e-19 glpE P Rhodanese Homology Domain
LEKHBMCO_00223 2.4e-27 xlyB 3.5.1.28 CBM50 M LysM domain
LEKHBMCO_00224 6.9e-160 asnA 6.3.1.1 F aspartate--ammonia ligase
LEKHBMCO_00225 7.9e-194 cydA 1.10.3.14 C ubiquinol oxidase
LEKHBMCO_00226 2.5e-141 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
LEKHBMCO_00227 2.7e-204 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
LEKHBMCO_00228 3.6e-220 cydD CO ABC transporter transmembrane region
LEKHBMCO_00229 1.1e-96 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LEKHBMCO_00230 1.5e-105 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
LEKHBMCO_00231 8.6e-157 ndh 1.6.99.3 C NADH dehydrogenase
LEKHBMCO_00232 1.5e-146 pbuO_1 S Permease family
LEKHBMCO_00234 2.4e-32 2.7.7.65 T GGDEF domain
LEKHBMCO_00235 1.7e-129 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
LEKHBMCO_00236 6.5e-183
LEKHBMCO_00237 5.8e-206 S Protein conserved in bacteria
LEKHBMCO_00238 1.2e-201 ydaM M Glycosyl transferase family group 2
LEKHBMCO_00239 0.0 ydaN S Bacterial cellulose synthase subunit
LEKHBMCO_00240 2.4e-113 2.7.7.65 T diguanylate cyclase activity
LEKHBMCO_00241 3.8e-38 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
LEKHBMCO_00242 1.9e-50 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
LEKHBMCO_00243 6.9e-309 L Helicase C-terminal domain protein
LEKHBMCO_00244 0.0 rafA 3.2.1.22 G alpha-galactosidase
LEKHBMCO_00245 8.9e-54 S Membrane
LEKHBMCO_00246 3.5e-64 K helix_turn_helix, arabinose operon control protein
LEKHBMCO_00247 1.5e-44
LEKHBMCO_00248 1.3e-204 pipD E Dipeptidase
LEKHBMCO_00249 1.1e-23 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
LEKHBMCO_00250 2e-191 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LEKHBMCO_00251 4.5e-60 speG J Acetyltransferase (GNAT) domain
LEKHBMCO_00252 2.3e-113 yitU 3.1.3.104 S hydrolase
LEKHBMCO_00253 1.6e-79 yjfP S COG1073 Hydrolases of the alpha beta superfamily
LEKHBMCO_00254 4.8e-81
LEKHBMCO_00255 2e-178 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
LEKHBMCO_00256 6.7e-42 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
LEKHBMCO_00257 1.4e-48 cps4C M Chain length determinant protein
LEKHBMCO_00258 9.4e-65 cpsD D AAA domain
LEKHBMCO_00259 1.2e-221 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 M Psort location CytoplasmicMembrane, score
LEKHBMCO_00260 2e-166 2.6.1.102 M Belongs to the DegT DnrJ EryC1 family
LEKHBMCO_00261 4.8e-77 epsL M Bacterial sugar transferase
LEKHBMCO_00262 2.2e-25 pglD 2.3.1.203 S Bacterial transferase hexapeptide (six repeats)
LEKHBMCO_00263 5.3e-121 2.4.1.52 GT4 M Glycosyl transferases group 1
LEKHBMCO_00264 1.8e-79 gtf1 2.4.1.52 GT4 M glycosyl transferase group 1
LEKHBMCO_00265 1.5e-75 M Glycosyltransferase Family 4
LEKHBMCO_00266 1e-42 GT2 V Glycosyl transferase, family 2
LEKHBMCO_00267 2.5e-57 pglI 2.4.1.293 GT2 M Glycosyltransferase like family 2
LEKHBMCO_00269 2.7e-52
LEKHBMCO_00270 2.3e-116 S Glycosyltransferase WbsX
LEKHBMCO_00271 3.5e-61 cps1B GT2,GT4 M Glycosyl transferases group 1
LEKHBMCO_00272 7.4e-95 cps2I S Psort location CytoplasmicMembrane, score
LEKHBMCO_00273 5.5e-147 lspL 5.1.3.6 GM RmlD substrate binding domain
LEKHBMCO_00274 3.7e-179 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LEKHBMCO_00275 3.4e-64 M Glycosyl transferases group 1
LEKHBMCO_00276 5.6e-126 M Glycosyl transferases group 1
LEKHBMCO_00279 3.4e-83 qorB 1.6.5.2 GM NmrA-like family
LEKHBMCO_00280 2.1e-39 K Transcriptional regulator
LEKHBMCO_00281 4.5e-30 S CHY zinc finger
LEKHBMCO_00282 1.9e-85 1.1.1.1 C Zinc-binding dehydrogenase
LEKHBMCO_00284 4.4e-41 S Protein of unknown function (DUF1211)
LEKHBMCO_00285 1.4e-25 ybl78 L Conserved phage C-terminus (Phg_2220_C)
LEKHBMCO_00287 2.5e-41 wecD M Acetyltransferase (GNAT) family
LEKHBMCO_00288 3.8e-75 cps2D 5.1.3.2 M RmlD substrate binding domain
LEKHBMCO_00289 9.5e-66 H Methyltransferase domain
LEKHBMCO_00291 1.3e-16 K DNA-templated transcription, initiation
LEKHBMCO_00293 2.2e-08 S Protein of unknown function (DUF2922)
LEKHBMCO_00296 8.3e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
LEKHBMCO_00297 1e-27 ysxB J Cysteine protease Prp
LEKHBMCO_00298 1.6e-42 rpmA J Belongs to the bacterial ribosomal protein bL27 family
LEKHBMCO_00299 4.7e-09 M LysM domain
LEKHBMCO_00302 9.7e-73
LEKHBMCO_00303 1.2e-100 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
LEKHBMCO_00304 1.3e-178 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
LEKHBMCO_00305 6e-123 xerC D Belongs to the 'phage' integrase family. XerC subfamily
LEKHBMCO_00306 7e-79 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LEKHBMCO_00307 7.8e-218 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LEKHBMCO_00308 4.6e-37 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LEKHBMCO_00309 4.5e-58 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LEKHBMCO_00310 1.1e-56 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LEKHBMCO_00311 5.8e-100 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LEKHBMCO_00312 4.5e-58 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LEKHBMCO_00313 1.3e-42 yeaL S Protein of unknown function (DUF441)
LEKHBMCO_00314 4.8e-125 cvfB S S1 domain
LEKHBMCO_00315 7.3e-113 xerD D recombinase XerD
LEKHBMCO_00316 1.1e-293 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
LEKHBMCO_00317 1.8e-76 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LEKHBMCO_00318 4.4e-189 nhaC C Na H antiporter NhaC
LEKHBMCO_00319 1e-64 ypsA S Belongs to the UPF0398 family
LEKHBMCO_00320 1.2e-196 ade 3.5.4.2 F Adenine deaminase C-terminal domain
LEKHBMCO_00322 4.4e-74 2.3.1.178 M GNAT acetyltransferase
LEKHBMCO_00323 2.3e-68 maa 2.3.1.79 S Maltose acetyltransferase
LEKHBMCO_00324 2.8e-56 3.6.1.27 I Acid phosphatase homologues
LEKHBMCO_00325 4.9e-22 XK27_07525 3.6.1.55 F Hydrolase of X-linked nucleoside diphosphate N terminal
LEKHBMCO_00327 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
LEKHBMCO_00328 5.2e-202 hsdM 2.1.1.72 V type I restriction-modification system
LEKHBMCO_00329 7e-27 L PFAM transposase IS200-family protein
LEKHBMCO_00330 5e-74 sdaAB 4.3.1.17 E Serine dehydratase beta chain
LEKHBMCO_00331 4.7e-112 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
LEKHBMCO_00332 7.7e-41 S Iron-sulfur cluster assembly protein
LEKHBMCO_00333 1.3e-66 S Protein of unknown function (DUF1440)
LEKHBMCO_00334 7.7e-82 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
LEKHBMCO_00335 9.2e-188 mtnE 2.6.1.83 E Aminotransferase
LEKHBMCO_00337 2.7e-15
LEKHBMCO_00338 6.6e-87 S Haloacid dehalogenase-like hydrolase
LEKHBMCO_00339 1.1e-37 blpT
LEKHBMCO_00342 5.5e-08
LEKHBMCO_00344 1.1e-16
LEKHBMCO_00349 6.6e-13 2.7.13.3 T GHKL domain
LEKHBMCO_00350 4.7e-23 2.7.13.3 T GHKL domain
LEKHBMCO_00351 1.3e-55 K LytTr DNA-binding domain
LEKHBMCO_00356 1.4e-70 xerD L Phage integrase, N-terminal SAM-like domain
LEKHBMCO_00357 4.8e-266 fbp 3.1.3.11 G phosphatase activity
LEKHBMCO_00358 1.9e-20 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LEKHBMCO_00359 6.2e-171 tonB M YSIRK type signal peptide
LEKHBMCO_00360 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
LEKHBMCO_00361 3e-98 fabK 1.3.1.9 S Nitronate monooxygenase
LEKHBMCO_00362 4.7e-163 ytbD EGP Major facilitator Superfamily
LEKHBMCO_00363 4e-110 IQ NAD dependent epimerase/dehydratase family
LEKHBMCO_00364 5.8e-104 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
LEKHBMCO_00365 4.5e-43 gutM K Glucitol operon activator protein (GutM)
LEKHBMCO_00366 4.8e-83 srlA G PTS system enzyme II sorbitol-specific factor
LEKHBMCO_00367 1.4e-136 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
LEKHBMCO_00368 2.4e-36 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
LEKHBMCO_00369 9.1e-63 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
LEKHBMCO_00370 5.5e-117 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
LEKHBMCO_00371 3.3e-136 pfoS S Phosphotransferase system, EIIC
LEKHBMCO_00373 2.6e-207 spaB S Lantibiotic dehydratase, C terminus
LEKHBMCO_00374 4.3e-184 spaT V ATPases associated with a variety of cellular activities
LEKHBMCO_00375 4.9e-75 spaC2 V Lanthionine synthetase C-like protein
LEKHBMCO_00376 8.8e-90 KT Transcriptional regulatory protein, C terminal
LEKHBMCO_00377 2.9e-105 2.7.13.3 T His Kinase A (phosphoacceptor) domain
LEKHBMCO_00378 6.9e-68 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
LEKHBMCO_00379 9.6e-47 V ABC-2 family transporter protein
LEKHBMCO_00381 2.5e-27 K Helix-turn-helix XRE-family like proteins
LEKHBMCO_00382 7.7e-20 S protein encoded in hypervariable junctions of pilus gene clusters
LEKHBMCO_00384 4.9e-224 E ABC transporter, substratebinding protein
LEKHBMCO_00385 3.6e-116 sufC O FeS assembly ATPase SufC
LEKHBMCO_00386 2.1e-142 sufD O FeS assembly protein SufD
LEKHBMCO_00387 3.3e-148 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LEKHBMCO_00388 4.9e-41 nifU C SUF system FeS assembly protein, NifU family
LEKHBMCO_00389 9.4e-240 sufB O assembly protein SufB
LEKHBMCO_00390 3.3e-45 S VIT family
LEKHBMCO_00391 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
LEKHBMCO_00392 1.5e-136 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LEKHBMCO_00393 2.1e-112 rssA S Phospholipase, patatin family
LEKHBMCO_00394 8.2e-16
LEKHBMCO_00395 1.5e-29
LEKHBMCO_00396 2.3e-79 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
LEKHBMCO_00397 1.2e-99 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LEKHBMCO_00398 1.8e-08 K transcriptional
LEKHBMCO_00399 5.2e-11 S Protein of unknown function (DUF805)
LEKHBMCO_00401 1.5e-78 yvfR V ABC transporter
LEKHBMCO_00402 1.9e-53 yvfS V ABC-2 type transporter
LEKHBMCO_00403 5.4e-57 salK 2.7.13.3 T Histidine kinase
LEKHBMCO_00404 2.4e-75 desR K helix_turn_helix, Lux Regulon
LEKHBMCO_00405 1.4e-70 ptp3 3.1.3.48 T Tyrosine phosphatase family
LEKHBMCO_00406 1.6e-90 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
LEKHBMCO_00410 1.1e-142 xerS L Phage integrase family
LEKHBMCO_00411 3.8e-70 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
LEKHBMCO_00412 6.5e-138 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LEKHBMCO_00413 1.6e-217 1.3.5.4 C FAD binding domain
LEKHBMCO_00414 4.6e-117 IQ Enoyl-(Acyl carrier protein) reductase
LEKHBMCO_00415 1.6e-138 G Xylose isomerase-like TIM barrel
LEKHBMCO_00416 1.3e-72 K Transcriptional regulator, LysR family
LEKHBMCO_00417 1.4e-98 EGP Major Facilitator Superfamily
LEKHBMCO_00418 7.5e-129 EGP Major Facilitator Superfamily
LEKHBMCO_00419 2.7e-81 L Integrase core domain
LEKHBMCO_00420 1.8e-20 L PFAM transposase IS3 IS911 family protein
LEKHBMCO_00421 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
LEKHBMCO_00422 1.7e-32 P Heavy-metal-associated domain
LEKHBMCO_00423 7.1e-17 tnp L Transposase IS66 family
LEKHBMCO_00424 8.8e-50 yugI 5.3.1.9 J general stress protein
LEKHBMCO_00425 2.7e-95 trxB2 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
LEKHBMCO_00426 3e-92 dedA S SNARE associated Golgi protein
LEKHBMCO_00427 7.8e-32 S Protein of unknown function (DUF1461)
LEKHBMCO_00428 2.9e-113 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LEKHBMCO_00429 1.9e-53 yutD S Protein of unknown function (DUF1027)
LEKHBMCO_00430 3e-57 S Calcineurin-like phosphoesterase
LEKHBMCO_00431 9.3e-184 cycA E Amino acid permease
LEKHBMCO_00432 7.6e-98 ytxK 2.1.1.72 L N-6 DNA Methylase
LEKHBMCO_00434 5.5e-11 S Putative Competence protein ComGF
LEKHBMCO_00436 1.5e-13
LEKHBMCO_00437 1.2e-27 comGC U competence protein ComGC
LEKHBMCO_00438 5.7e-98 comGB NU type II secretion system
LEKHBMCO_00439 4.7e-121 comGA NU Type II IV secretion system protein
LEKHBMCO_00440 2.1e-102 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LEKHBMCO_00441 1.5e-119 yebC K Transcriptional regulatory protein
LEKHBMCO_00442 3.7e-42 S VanZ like family
LEKHBMCO_00443 1.3e-158 ccpA K catabolite control protein A
LEKHBMCO_00444 2.5e-171 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
LEKHBMCO_00445 1.5e-13
LEKHBMCO_00448 5.9e-75 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LEKHBMCO_00449 7.1e-35 K helix_turn_helix, Arsenical Resistance Operon Repressor
LEKHBMCO_00450 5.2e-65 hly S protein, hemolysin III
LEKHBMCO_00451 7.3e-41 M1-874 K Domain of unknown function (DUF1836)
LEKHBMCO_00452 9.4e-84 S membrane
LEKHBMCO_00453 1.1e-79 S VIT family
LEKHBMCO_00454 1.8e-148 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
LEKHBMCO_00455 7.9e-56 P Plays a role in the regulation of phosphate uptake
LEKHBMCO_00456 1.8e-115 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LEKHBMCO_00457 2.7e-114 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LEKHBMCO_00458 1.1e-121 pstA P Phosphate transport system permease protein PstA
LEKHBMCO_00459 4.1e-119 pstC P probably responsible for the translocation of the substrate across the membrane
LEKHBMCO_00460 3.2e-97 pstS P Phosphate
LEKHBMCO_00461 1.3e-41 yjbH Q Thioredoxin
LEKHBMCO_00462 1.5e-232 pepF E oligoendopeptidase F
LEKHBMCO_00463 1.1e-68 coiA 3.6.4.12 S Competence protein
LEKHBMCO_00464 3.5e-47 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
LEKHBMCO_00465 6.3e-115 S N-acetylmuramoyl-L-alanine amidase activity
LEKHBMCO_00466 1.5e-19 S Bacteriophage holin of superfamily 6 (Holin_LLH)
LEKHBMCO_00471 2.2e-71 S Domain of unknown function (DUF2479)
LEKHBMCO_00473 2.4e-59 M Prophage endopeptidase tail
LEKHBMCO_00474 2.7e-61 S Phage tail protein
LEKHBMCO_00475 4.4e-110 S peptidoglycan catabolic process
LEKHBMCO_00476 2.8e-39 S Bacteriophage Gp15 protein
LEKHBMCO_00478 7.5e-38 N domain, Protein
LEKHBMCO_00479 4.2e-15 S Minor capsid protein from bacteriophage
LEKHBMCO_00480 7.9e-16 S Minor capsid protein
LEKHBMCO_00481 2.6e-29 S Minor capsid protein
LEKHBMCO_00482 2e-14
LEKHBMCO_00483 2.5e-97 S T=7 icosahedral viral capsid
LEKHBMCO_00484 2.1e-25 S Phage minor structural protein GP20
LEKHBMCO_00486 1.4e-95 S Phage minor capsid protein 2
LEKHBMCO_00487 1.1e-143 S Phage portal protein, SPP1 Gp6-like
LEKHBMCO_00488 3.8e-166 S Terminase RNAseH like domain
LEKHBMCO_00489 5.3e-41
LEKHBMCO_00491 8.5e-11 arpU S Phage transcriptional regulator, ArpU family
LEKHBMCO_00497 6e-72 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
LEKHBMCO_00499 8.5e-59 L Belongs to the 'phage' integrase family
LEKHBMCO_00500 9.5e-18 S HNH endonuclease
LEKHBMCO_00501 8.2e-09
LEKHBMCO_00504 3.1e-41 S Protein of unknown function (DUF1064)
LEKHBMCO_00506 1.8e-40 S Protein of unknown function (DUF1064)
LEKHBMCO_00507 8.3e-19
LEKHBMCO_00508 2.8e-123 dnaB 3.6.4.12 L DnaB-like helicase C terminal domain
LEKHBMCO_00509 1e-37 S calcium ion binding
LEKHBMCO_00510 3e-90 S Putative HNHc nuclease
LEKHBMCO_00511 1.2e-34 S Protein of unknown function (DUF669)
LEKHBMCO_00512 7.3e-73 S AAA domain
LEKHBMCO_00513 1.9e-26 S Bacteriophage Mu Gam like protein
LEKHBMCO_00519 6.6e-19
LEKHBMCO_00520 1.4e-15 S Hypothetical protein (DUF2513)
LEKHBMCO_00523 3.7e-12 K Cro/C1-type HTH DNA-binding domain
LEKHBMCO_00524 1.7e-43 K addiction module antidote protein HigA
LEKHBMCO_00525 1.7e-39 E IrrE N-terminal-like domain
LEKHBMCO_00526 5.2e-168 J Domain of unknown function (DUF4041)
LEKHBMCO_00527 3.5e-26 L PFAM transposase IS200-family protein
LEKHBMCO_00528 3.6e-69 L HTH-like domain
LEKHBMCO_00529 5.9e-30 L Helix-turn-helix domain
LEKHBMCO_00530 4.2e-208 G glycerol-3-phosphate transporter
LEKHBMCO_00531 1.7e-46 3.6.4.12 S PD-(D/E)XK nuclease family transposase
LEKHBMCO_00532 5.9e-88 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
LEKHBMCO_00533 3.3e-25 K MarR family transcriptional regulator
LEKHBMCO_00534 4.4e-40 1.6.5.2 GM NAD(P)H-binding
LEKHBMCO_00535 1.5e-72 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LEKHBMCO_00536 3.7e-145 htrA 3.4.21.107 O serine protease
LEKHBMCO_00537 1.3e-116 vicX 3.1.26.11 S domain protein
LEKHBMCO_00538 1.8e-30 yyaQ S YjbR
LEKHBMCO_00539 5.6e-80 yycI S YycH protein
LEKHBMCO_00540 6e-103 yycH S YycH protein
LEKHBMCO_00541 1.1e-272 vicK 2.7.13.3 T Histidine kinase
LEKHBMCO_00542 9e-114 K response regulator
LEKHBMCO_00543 6.3e-85 yxeH S hydrolase
LEKHBMCO_00545 1.1e-96 S Domain of unknown function DUF87
LEKHBMCO_00547 1.1e-229 V ABC transporter transmembrane region
LEKHBMCO_00548 3.1e-216 XK27_09600 V ABC transporter, ATP-binding protein
LEKHBMCO_00549 1.2e-31 K Transcriptional regulator, MarR family
LEKHBMCO_00550 2.9e-172 S Putative peptidoglycan binding domain
LEKHBMCO_00552 4e-23 relB L RelB antitoxin
LEKHBMCO_00553 8.4e-62 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
LEKHBMCO_00554 1.1e-139 gldA 1.1.1.6 C Iron-containing alcohol dehydrogenase
LEKHBMCO_00555 4.4e-179 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
LEKHBMCO_00556 1.7e-95 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
LEKHBMCO_00557 6e-08 mccA 2.5.1.134, 2.5.1.47 E Pyridoxal-phosphate dependent enzyme
LEKHBMCO_00558 1.8e-222 pepF E Oligopeptidase F
LEKHBMCO_00559 2.2e-96 yicL EG EamA-like transporter family
LEKHBMCO_00560 2.4e-69 2.3.1.178 J Acetyltransferase (GNAT) domain
LEKHBMCO_00561 4.4e-170 yjjP S Putative threonine/serine exporter
LEKHBMCO_00562 2.8e-109 glcU U sugar transport
LEKHBMCO_00563 3.8e-14 yobS K transcriptional regulator
LEKHBMCO_00564 3.8e-152 mdtG EGP Major facilitator Superfamily
LEKHBMCO_00565 3.1e-106 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
LEKHBMCO_00566 2.2e-224 yxbA 6.3.1.12 S ATP-grasp enzyme
LEKHBMCO_00567 5.7e-230 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LEKHBMCO_00568 3.6e-17 yneR
LEKHBMCO_00569 7.4e-248 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
LEKHBMCO_00570 1.6e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LEKHBMCO_00571 3.3e-12 yiiE S Protein of unknown function (DUF1211)
LEKHBMCO_00572 3.7e-37 yiiE S Protein of unknown function (DUF1211)
LEKHBMCO_00573 0.0 asnB 6.3.5.4 E Asparagine synthase
LEKHBMCO_00574 7.4e-64 D peptidase
LEKHBMCO_00575 3.6e-116 S Glycosyl transferase family 2
LEKHBMCO_00576 2.5e-110 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
LEKHBMCO_00577 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LEKHBMCO_00578 2.4e-58 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LEKHBMCO_00579 4.8e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
LEKHBMCO_00580 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LEKHBMCO_00581 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LEKHBMCO_00582 9.3e-153 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LEKHBMCO_00583 9e-20 yaaA S S4 domain protein YaaA
LEKHBMCO_00584 3.9e-159 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LEKHBMCO_00585 2.1e-204 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LEKHBMCO_00586 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
LEKHBMCO_00587 2.2e-49 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LEKHBMCO_00588 1.8e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LEKHBMCO_00589 1.1e-199 nupG F Nucleoside
LEKHBMCO_00590 1.5e-122 MA20_14895 S Conserved hypothetical protein 698
LEKHBMCO_00591 4.9e-53 K LysR substrate binding domain
LEKHBMCO_00592 9.6e-09
LEKHBMCO_00593 2.3e-65 yxkH G Polysaccharide deacetylase
LEKHBMCO_00594 2.6e-29 yqkB S Belongs to the HesB IscA family
LEKHBMCO_00595 0.0 pacL 3.6.3.8 P P-type ATPase
LEKHBMCO_00596 2.4e-109 3.1.4.46 C phosphodiesterase
LEKHBMCO_00597 1.2e-126 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
LEKHBMCO_00598 2.4e-101 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
LEKHBMCO_00599 1.4e-81 noc K Belongs to the ParB family
LEKHBMCO_00600 6.5e-118 soj D Sporulation initiation inhibitor
LEKHBMCO_00601 1.8e-108 spo0J K Belongs to the ParB family
LEKHBMCO_00602 3.4e-23 yyzM S Bacterial protein of unknown function (DUF951)
LEKHBMCO_00603 5.4e-190 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LEKHBMCO_00604 6.5e-54 XK27_01040 S Protein of unknown function (DUF1129)
LEKHBMCO_00605 7.6e-38
LEKHBMCO_00606 1e-103 psaA P Belongs to the bacterial solute-binding protein 9 family
LEKHBMCO_00607 1e-98 fhuC P ABC transporter
LEKHBMCO_00608 2.5e-96 znuB U ABC 3 transport family
LEKHBMCO_00609 1.5e-55 S ECF transporter, substrate-specific component
LEKHBMCO_00610 1e-102 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
LEKHBMCO_00611 1.7e-89 S NADPH-dependent FMN reductase
LEKHBMCO_00612 1.2e-27 yraB K transcriptional regulator
LEKHBMCO_00613 5.3e-68 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
LEKHBMCO_00615 2.9e-153 EGP Major facilitator Superfamily
LEKHBMCO_00616 2.3e-58 S Haloacid dehalogenase-like hydrolase
LEKHBMCO_00617 9.1e-89 yvyE 3.4.13.9 S YigZ family
LEKHBMCO_00618 3e-39 S CAAX protease self-immunity
LEKHBMCO_00619 2.6e-117 cps1D M Domain of unknown function (DUF4422)
LEKHBMCO_00620 2.5e-61 S Glycosyltransferase like family 2
LEKHBMCO_00621 1.3e-75 S Glycosyltransferase like family 2
LEKHBMCO_00622 1.2e-144 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LEKHBMCO_00623 4.2e-101 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
LEKHBMCO_00624 6.2e-164 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LEKHBMCO_00625 9.9e-128 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LEKHBMCO_00626 9.4e-118 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
LEKHBMCO_00627 9.8e-27 S zinc-ribbon domain
LEKHBMCO_00628 2e-80 S response to antibiotic
LEKHBMCO_00629 1.4e-31 G Glycosyltransferase Family 4
LEKHBMCO_00630 6.8e-47 2.3.1.79 S Hexapeptide repeat of succinyl-transferase
LEKHBMCO_00631 3.7e-84 M Glycosyl transferase family 2
LEKHBMCO_00632 2.2e-39 M Glycosyl transferase family 2
LEKHBMCO_00633 7.3e-46 S Glycosyl transferase family 2
LEKHBMCO_00635 1.3e-42 M Glycosyltransferase like family 2
LEKHBMCO_00636 5.8e-26 S Acetyltransferase (Isoleucine patch superfamily)
LEKHBMCO_00637 6.3e-130 S Membrane protein involved in the export of O-antigen and teichoic acid
LEKHBMCO_00638 3e-41 S Acyltransferase family
LEKHBMCO_00639 1.2e-43
LEKHBMCO_00640 3.2e-214 ugd 1.1.1.22 M UDP binding domain
LEKHBMCO_00641 2.6e-77 epsB M biosynthesis protein
LEKHBMCO_00642 9.3e-82 ywqD 2.7.10.1 D Capsular exopolysaccharide family
LEKHBMCO_00643 1.6e-111 ywqE 3.1.3.48 GM PHP domain protein
LEKHBMCO_00644 1.8e-125 brpA K Cell envelope-like function transcriptional attenuator common domain protein
LEKHBMCO_00645 2e-91 rfbP M Bacterial sugar transferase
LEKHBMCO_00646 1.8e-95 M Core-2/I-Branching enzyme
LEKHBMCO_00647 1.6e-194 glf 5.4.99.9 M UDP-galactopyranose mutase
LEKHBMCO_00648 3.7e-65 S Glycosyltransferase like family 2
LEKHBMCO_00649 2e-160 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
LEKHBMCO_00650 5.8e-57 cps3F
LEKHBMCO_00651 9.8e-74 M transferase activity, transferring glycosyl groups
LEKHBMCO_00652 2e-69 rny D Peptidase family M23
LEKHBMCO_00654 3.4e-19 tnp
LEKHBMCO_00655 5.8e-44 L hmm pf00665
LEKHBMCO_00656 1.1e-98 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
LEKHBMCO_00657 1.2e-84 dps P Ferritin-like domain
LEKHBMCO_00658 2e-159 L transposase, IS605 OrfB family
LEKHBMCO_00659 1.2e-57 tlpA2 L Transposase IS200 like
LEKHBMCO_00660 4.1e-53 1.14.12.17 C Oxidoreductase NAD-binding domain
LEKHBMCO_00662 9e-102 qmcA O prohibitin homologues
LEKHBMCO_00663 4.7e-26 S protein encoded in hypervariable junctions of pilus gene clusters
LEKHBMCO_00664 0.0 O Belongs to the peptidase S8 family
LEKHBMCO_00665 1e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LEKHBMCO_00666 7.3e-118 O AAA domain (Cdc48 subfamily)
LEKHBMCO_00667 4.1e-67
LEKHBMCO_00668 4.2e-89 hsdS 3.1.21.3 L Type I restriction modification DNA specificity domain
LEKHBMCO_00669 4e-225 hsdM 2.1.1.72 V type I restriction-modification system
LEKHBMCO_00670 2.4e-286 hsdR 3.1.21.3 L DEAD/DEAH box helicase
LEKHBMCO_00671 4.4e-07
LEKHBMCO_00672 1.1e-45 yjaB_1 K Acetyltransferase (GNAT) domain
LEKHBMCO_00673 3.5e-80 yitS S EDD domain protein, DegV family
LEKHBMCO_00674 1.9e-57 racA K Domain of unknown function (DUF1836)
LEKHBMCO_00675 6.1e-116 queH 1.17.99.6, 3.1.26.4 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LEKHBMCO_00676 2.7e-48 ald 1.4.1.1 C Belongs to the AlaDH PNT family
LEKHBMCO_00677 5.4e-87 ald 1.4.1.1 C Belongs to the AlaDH PNT family
LEKHBMCO_00678 1.3e-161 potE2 E amino acid
LEKHBMCO_00681 4.6e-24
LEKHBMCO_00682 6.9e-15
LEKHBMCO_00683 7.4e-92 pstS P T5orf172
LEKHBMCO_00684 1.8e-257 yeeB L DEAD-like helicases superfamily
LEKHBMCO_00685 6.9e-206 yeeA V Type II restriction enzyme, methylase subunits
LEKHBMCO_00690 2.4e-19 M domain protein
LEKHBMCO_00692 4.5e-22 agrA KT Response regulator of the LytR AlgR family
LEKHBMCO_00693 4.1e-44 blpH 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
LEKHBMCO_00695 0.0 pepN 3.4.11.2 E aminopeptidase
LEKHBMCO_00696 1.9e-35
LEKHBMCO_00698 7.6e-125 D CobQ CobB MinD ParA nucleotide binding domain protein
LEKHBMCO_00699 2.7e-64 licT K transcriptional antiterminator
LEKHBMCO_00700 1.3e-202 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G Pts system
LEKHBMCO_00701 3.5e-173 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LEKHBMCO_00702 1.7e-38 S Replication initiator protein A (RepA) N-terminus
LEKHBMCO_00703 9.4e-109 L Initiator Replication protein
LEKHBMCO_00704 6.1e-08 yokH G regulation of fungal-type cell wall biogenesis
LEKHBMCO_00706 6.5e-12 L PLD-like domain
LEKHBMCO_00707 3.5e-23 L PLD-like domain
LEKHBMCO_00708 3.6e-73 L HTH-like domain
LEKHBMCO_00709 2.6e-30 L Helix-turn-helix domain
LEKHBMCO_00710 6.1e-107 L PLD-like domain
LEKHBMCO_00712 1.3e-10 tcdC
LEKHBMCO_00714 8.8e-231 tetP J elongation factor G
LEKHBMCO_00715 1.2e-31 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LEKHBMCO_00717 2e-216 yjeM E Amino Acid
LEKHBMCO_00718 5.3e-62 yphA GM NAD dependent epimerase/dehydratase family
LEKHBMCO_00719 1.5e-75 K Helix-turn-helix domain, rpiR family
LEKHBMCO_00720 2.5e-92 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
LEKHBMCO_00721 2.3e-127 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
LEKHBMCO_00722 2.2e-90 nanK GK ROK family
LEKHBMCO_00723 3.8e-54 ndk 2.7.4.6 F Belongs to the NDK family
LEKHBMCO_00724 5.7e-63 G Xylose isomerase domain protein TIM barrel
LEKHBMCO_00725 1.1e-153 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LEKHBMCO_00726 1.3e-199 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LEKHBMCO_00727 8.1e-136 tetA EGP Major facilitator Superfamily
LEKHBMCO_00728 1.8e-32 yvdC S MazG nucleotide pyrophosphohydrolase domain
LEKHBMCO_00729 2.5e-214 yjeM E Amino Acid
LEKHBMCO_00730 1.9e-190 glnPH2 P ABC transporter permease
LEKHBMCO_00731 2.3e-112 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
LEKHBMCO_00732 6.3e-44 E GDSL-like Lipase/Acylhydrolase
LEKHBMCO_00733 1e-133 coaA 2.7.1.33 F Pantothenic acid kinase
LEKHBMCO_00734 7.6e-275 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
LEKHBMCO_00735 3.3e-82
LEKHBMCO_00736 8.5e-34 S Predicted membrane protein (DUF2142)
LEKHBMCO_00737 8.5e-115 rfbJ M Glycosyl transferase family 2
LEKHBMCO_00738 2.1e-30 gtcA S Teichoic acid glycosylation protein
LEKHBMCO_00739 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
LEKHBMCO_00740 1.2e-160 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LEKHBMCO_00741 4.7e-96 dacA 3.4.16.4 M Belongs to the peptidase S11 family
LEKHBMCO_00742 5.4e-67 XK27_09620 S NADPH-dependent FMN reductase
LEKHBMCO_00743 2.7e-156 XK27_09615 S reductase
LEKHBMCO_00744 3e-10 2.7.7.65 T phosphorelay sensor kinase activity
LEKHBMCO_00745 3.3e-146 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
LEKHBMCO_00746 1.5e-55 S Psort location CytoplasmicMembrane, score
LEKHBMCO_00747 3.6e-14
LEKHBMCO_00748 1.7e-39 S Bacterial membrane protein, YfhO
LEKHBMCO_00749 8.5e-22 S Bacterial membrane protein, YfhO
LEKHBMCO_00750 8.8e-102 S Bacterial membrane protein, YfhO
LEKHBMCO_00751 3.2e-129 S Bacterial membrane protein YfhO
LEKHBMCO_00752 1.3e-147 XK27_08315 M Sulfatase
LEKHBMCO_00753 1e-147 scrR K helix_turn _helix lactose operon repressor
LEKHBMCO_00754 1.4e-217 scrB 3.2.1.26 GH32 G invertase
LEKHBMCO_00755 6.1e-282 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
LEKHBMCO_00756 2e-183 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
LEKHBMCO_00757 2.1e-114 ntpJ P Potassium uptake protein
LEKHBMCO_00758 2.2e-58 ktrA P TrkA-N domain
LEKHBMCO_00759 5.7e-54 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
LEKHBMCO_00760 1.1e-43 K helix_turn_helix isocitrate lyase regulation
LEKHBMCO_00761 5.3e-120 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEKHBMCO_00762 1.4e-102 pfoS S Phosphotransferase system, EIIC
LEKHBMCO_00763 1.4e-19
LEKHBMCO_00764 2e-93 S Predicted membrane protein (DUF2207)
LEKHBMCO_00765 1.2e-54 bioY S BioY family
LEKHBMCO_00766 5.7e-184 lmrB EGP Major facilitator Superfamily
LEKHBMCO_00767 2.5e-95 dacA 3.4.16.4 M Belongs to the peptidase S11 family
LEKHBMCO_00768 7.6e-74 glcR K DeoR C terminal sensor domain
LEKHBMCO_00769 1e-60 yceE S haloacid dehalogenase-like hydrolase
LEKHBMCO_00770 1.9e-41 S CAAX protease self-immunity
LEKHBMCO_00771 1.2e-33 S Domain of unknown function (DUF4811)
LEKHBMCO_00772 2.1e-197 lmrB EGP Major facilitator Superfamily
LEKHBMCO_00773 4.2e-32 merR K MerR HTH family regulatory protein
LEKHBMCO_00774 1.8e-39 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEKHBMCO_00775 1.2e-58 S Protein of unknown function (DUF554)
LEKHBMCO_00776 3.3e-259 treB G phosphotransferase system
LEKHBMCO_00777 5.7e-84 treR K UTRA
LEKHBMCO_00778 6.3e-251 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
LEKHBMCO_00779 6.4e-168 mdtG EGP Major facilitator Superfamily
LEKHBMCO_00781 5.7e-194 XK27_08315 M Sulfatase
LEKHBMCO_00782 5e-57 S peptidoglycan catabolic process
LEKHBMCO_00783 5.6e-89 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LEKHBMCO_00784 1.5e-167 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
LEKHBMCO_00785 2.4e-128 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
LEKHBMCO_00786 4.1e-177 thrC 4.2.3.1 E Threonine synthase
LEKHBMCO_00787 6e-82 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LEKHBMCO_00788 2.2e-122 yvgN C Aldo keto reductase
LEKHBMCO_00789 2.2e-70 K DeoR C terminal sensor domain
LEKHBMCO_00790 6.8e-46 pts36A 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LEKHBMCO_00791 6.9e-42 sgcB 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
LEKHBMCO_00792 1.2e-216 pts36C G PTS system sugar-specific permease component
LEKHBMCO_00794 2.3e-104 4.1.2.17 G Class II Aldolase and Adducin N-terminal domain
LEKHBMCO_00796 5.4e-58 S COG NOG19168 non supervised orthologous group
LEKHBMCO_00797 4.9e-190 XK27_11280 S Psort location CytoplasmicMembrane, score
LEKHBMCO_00798 7.1e-15 L Plasmid pRiA4b ORF-3-like protein
LEKHBMCO_00799 9e-106 L Belongs to the 'phage' integrase family
LEKHBMCO_00800 5.6e-18 3.1.21.3 V Type I restriction modification DNA specificity domain
LEKHBMCO_00801 6.6e-60 hsdM 2.1.1.72 V type I restriction-modification system
LEKHBMCO_00803 2.3e-125 L T/G mismatch-specific endonuclease activity
LEKHBMCO_00804 4.5e-20 L T/G mismatch-specific endonuclease activity
LEKHBMCO_00808 7.4e-177 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LEKHBMCO_00809 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
LEKHBMCO_00810 9.7e-194 cycA E Amino acid permease
LEKHBMCO_00811 8.3e-187 ytgP S Polysaccharide biosynthesis protein
LEKHBMCO_00812 1.1e-61 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LEKHBMCO_00813 1.2e-80 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LEKHBMCO_00814 5.1e-193 pepV 3.5.1.18 E dipeptidase PepV
LEKHBMCO_00815 3.3e-182 S Protein of unknown function DUF262
LEKHBMCO_00817 3e-36
LEKHBMCO_00818 1.3e-65 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LEKHBMCO_00819 4.2e-61 marR K Transcriptional regulator, MarR family
LEKHBMCO_00820 6.4e-102 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LEKHBMCO_00821 2.2e-27 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
LEKHBMCO_00822 6.5e-104 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
LEKHBMCO_00823 1.4e-98 IQ reductase
LEKHBMCO_00824 1.8e-194 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LEKHBMCO_00825 7.9e-47 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LEKHBMCO_00826 1.5e-63 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LEKHBMCO_00827 9.3e-216 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
LEKHBMCO_00828 2.7e-125 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LEKHBMCO_00829 2.3e-102 accA 2.1.3.15, 6.4.1.2 I alpha subunit
LEKHBMCO_00830 5.5e-109 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
LEKHBMCO_00831 1.6e-229 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LEKHBMCO_00832 3.1e-240 pgi 5.3.1.9 G Belongs to the GPI family
LEKHBMCO_00833 2.7e-302 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
LEKHBMCO_00834 5.7e-119 gla U Major intrinsic protein
LEKHBMCO_00835 9.9e-45 ykuL S CBS domain
LEKHBMCO_00836 1.5e-60 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LEKHBMCO_00837 4.1e-177 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LEKHBMCO_00838 6.2e-88 ykuT M mechanosensitive ion channel
LEKHBMCO_00840 1e-285 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LEKHBMCO_00841 2e-21 yheA S Belongs to the UPF0342 family
LEKHBMCO_00842 5e-128 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
LEKHBMCO_00843 6.6e-114 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LEKHBMCO_00845 5.4e-53 hit FG histidine triad
LEKHBMCO_00846 2.8e-94 ecsA V ABC transporter, ATP-binding protein
LEKHBMCO_00847 1.3e-72 ecsB U ABC transporter
LEKHBMCO_00848 1.6e-98 ytmP 2.7.1.89 M Choline/ethanolamine kinase
LEKHBMCO_00849 7.9e-101 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LEKHBMCO_00850 4e-45 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
LEKHBMCO_00851 6.8e-76 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LEKHBMCO_00852 9e-240 sftA D Belongs to the FtsK SpoIIIE SftA family
LEKHBMCO_00853 7.6e-223 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
LEKHBMCO_00854 2.5e-61 phaJ I N-terminal half of MaoC dehydratase
LEKHBMCO_00855 6.7e-69 ybhL S Belongs to the BI1 family
LEKHBMCO_00856 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LEKHBMCO_00857 3.3e-107 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LEKHBMCO_00858 2.1e-50 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LEKHBMCO_00859 6.1e-66 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LEKHBMCO_00860 1.6e-79 dnaB L replication initiation and membrane attachment
LEKHBMCO_00861 2.2e-107 dnaI L Primosomal protein DnaI
LEKHBMCO_00862 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LEKHBMCO_00863 1.3e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LEKHBMCO_00864 1.4e-24 rpmI J Belongs to the bacterial ribosomal protein bL35 family
LEKHBMCO_00865 7.7e-53 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LEKHBMCO_00866 2.5e-71 yqeG S HAD phosphatase, family IIIA
LEKHBMCO_00867 7.9e-181 yqeH S Ribosome biogenesis GTPase YqeH
LEKHBMCO_00868 1e-29 yhbY J RNA-binding protein
LEKHBMCO_00869 2.7e-77 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LEKHBMCO_00870 1.2e-71 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
LEKHBMCO_00871 1.5e-48 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LEKHBMCO_00872 4.2e-82 H Nodulation protein S (NodS)
LEKHBMCO_00873 1.3e-122 ylbM S Belongs to the UPF0348 family
LEKHBMCO_00874 2e-57 yceD S Uncharacterized ACR, COG1399
LEKHBMCO_00875 1.9e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
LEKHBMCO_00876 8.8e-89 plsC 2.3.1.51 I Acyltransferase
LEKHBMCO_00877 2.1e-92 yabB 2.1.1.223 L Methyltransferase small domain
LEKHBMCO_00878 1.5e-27 yazA L GIY-YIG catalytic domain protein
LEKHBMCO_00879 1.9e-128 rpsB J Belongs to the universal ribosomal protein uS2 family
LEKHBMCO_00880 2.7e-128 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LEKHBMCO_00881 6.9e-37
LEKHBMCO_00882 3.4e-92 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
LEKHBMCO_00883 4.1e-57 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LEKHBMCO_00884 3.8e-159 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LEKHBMCO_00885 7.9e-225 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LEKHBMCO_00886 8.6e-107 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
LEKHBMCO_00888 3.1e-111 K response regulator
LEKHBMCO_00889 5e-167 arlS 2.7.13.3 T Histidine kinase
LEKHBMCO_00890 1.6e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LEKHBMCO_00891 9.7e-24 acyP 3.6.1.7 C Belongs to the acylphosphatase family
LEKHBMCO_00892 4.3e-137 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
LEKHBMCO_00893 7.3e-105
LEKHBMCO_00894 7.2e-117
LEKHBMCO_00895 1.3e-41 dut S dUTPase
LEKHBMCO_00896 2.1e-94 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LEKHBMCO_00897 3.7e-46 yqhY S Asp23 family, cell envelope-related function
LEKHBMCO_00898 1.9e-36 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LEKHBMCO_00899 1.7e-103 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LEKHBMCO_00900 1.2e-146 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LEKHBMCO_00901 1.2e-16 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LEKHBMCO_00902 4.7e-83 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LEKHBMCO_00903 1.2e-120 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
LEKHBMCO_00904 6.6e-49 argR K Regulates arginine biosynthesis genes
LEKHBMCO_00905 2.1e-177 recN L May be involved in recombinational repair of damaged DNA
LEKHBMCO_00906 7.2e-83 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LEKHBMCO_00907 2.2e-30 ynzC S UPF0291 protein
LEKHBMCO_00908 7.7e-27 yneF S UPF0154 protein
LEKHBMCO_00909 1.8e-91 engB D Necessary for normal cell division and for the maintenance of normal septation
LEKHBMCO_00910 5.4e-44 MA20_27270 S mazG nucleotide pyrophosphohydrolase
LEKHBMCO_00911 1.2e-74 yciQ P membrane protein (DUF2207)
LEKHBMCO_00912 3e-19 D nuclear chromosome segregation
LEKHBMCO_00913 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
LEKHBMCO_00914 1.6e-38 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LEKHBMCO_00915 7.4e-70 gluP 3.4.21.105 S Peptidase, S54 family
LEKHBMCO_00916 1.5e-25 yqgQ S Bacterial protein of unknown function (DUF910)
LEKHBMCO_00917 4.7e-158 glk 2.7.1.2 G Glucokinase
LEKHBMCO_00918 2.7e-46 yqhL P Rhodanese-like protein
LEKHBMCO_00919 9.7e-17 WQ51_02665 S Protein of unknown function (DUF3042)
LEKHBMCO_00920 3.5e-110 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LEKHBMCO_00921 1.8e-205 ynbB 4.4.1.1 P aluminum resistance
LEKHBMCO_00922 1.3e-45 glnR K Transcriptional regulator
LEKHBMCO_00923 2e-247 glnA 6.3.1.2 E glutamine synthetase
LEKHBMCO_00925 7.6e-37 ogt 2.1.1.63 H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LEKHBMCO_00926 2.7e-48 S Domain of unknown function (DUF956)
LEKHBMCO_00927 6.3e-115 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
LEKHBMCO_00928 7.2e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LEKHBMCO_00929 3.8e-105 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LEKHBMCO_00930 5.1e-102 cdsA 2.7.7.41 S Belongs to the CDS family
LEKHBMCO_00931 4.1e-157 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
LEKHBMCO_00932 5.9e-260 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LEKHBMCO_00933 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LEKHBMCO_00934 2.7e-66 rimP J Required for maturation of 30S ribosomal subunits
LEKHBMCO_00935 4.8e-170 nusA K Participates in both transcription termination and antitermination
LEKHBMCO_00936 1.4e-39 ylxR K Protein of unknown function (DUF448)
LEKHBMCO_00937 6.8e-26 ylxQ J ribosomal protein
LEKHBMCO_00938 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LEKHBMCO_00939 2.2e-55 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LEKHBMCO_00940 1.4e-119 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LEKHBMCO_00941 2.5e-95 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
LEKHBMCO_00942 1.4e-131 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LEKHBMCO_00943 4.2e-56 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LEKHBMCO_00944 1.5e-274 dnaK O Heat shock 70 kDa protein
LEKHBMCO_00945 1.2e-160 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LEKHBMCO_00946 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LEKHBMCO_00948 9.2e-206 glnP P ABC transporter
LEKHBMCO_00949 2.6e-119 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
LEKHBMCO_00950 1.5e-31
LEKHBMCO_00951 2e-111 ampC V Beta-lactamase
LEKHBMCO_00952 3.5e-110 cobQ S glutamine amidotransferase
LEKHBMCO_00953 4.7e-220 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
LEKHBMCO_00954 6.8e-86 tdk 2.7.1.21 F thymidine kinase
LEKHBMCO_00955 2.3e-177 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LEKHBMCO_00956 1.4e-89 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LEKHBMCO_00957 7.7e-135 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LEKHBMCO_00958 5e-100 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LEKHBMCO_00959 4.5e-97 atpB C it plays a direct role in the translocation of protons across the membrane
LEKHBMCO_00960 1.8e-15 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LEKHBMCO_00961 2.4e-39 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LEKHBMCO_00962 2.7e-57 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LEKHBMCO_00963 6.3e-266 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LEKHBMCO_00964 1.3e-141 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LEKHBMCO_00965 4.8e-236 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LEKHBMCO_00966 3.9e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
LEKHBMCO_00967 4.1e-15 ywzB S Protein of unknown function (DUF1146)
LEKHBMCO_00968 2.7e-196 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LEKHBMCO_00969 3.4e-167 mbl D Cell shape determining protein MreB Mrl
LEKHBMCO_00970 1.2e-26 yidD S Could be involved in insertion of integral membrane proteins into the membrane
LEKHBMCO_00971 1.8e-12 S Protein of unknown function (DUF2969)
LEKHBMCO_00972 6.1e-187 rodA D Belongs to the SEDS family
LEKHBMCO_00973 3.5e-26 arsC 1.20.4.1 P Belongs to the ArsC family
LEKHBMCO_00974 5.6e-94 2.7.1.89 M Phosphotransferase enzyme family
LEKHBMCO_00975 1.1e-102 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
LEKHBMCO_00976 2.5e-21 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LEKHBMCO_00977 4.4e-121 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LEKHBMCO_00978 2.4e-288 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LEKHBMCO_00979 5.8e-140 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LEKHBMCO_00980 2.2e-153 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LEKHBMCO_00981 3.3e-90 stp 3.1.3.16 T phosphatase
LEKHBMCO_00982 3.4e-191 KLT serine threonine protein kinase
LEKHBMCO_00983 1.8e-111 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LEKHBMCO_00984 3.8e-58 thiN 2.7.6.2 H thiamine pyrophosphokinase
LEKHBMCO_00985 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
LEKHBMCO_00986 4.5e-53 asp S Asp23 family, cell envelope-related function
LEKHBMCO_00987 2.8e-238 yloV S DAK2 domain fusion protein YloV
LEKHBMCO_00988 3.3e-246 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LEKHBMCO_00989 1.6e-140 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LEKHBMCO_00990 7e-26 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
LEKHBMCO_00991 1.1e-100 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LEKHBMCO_00992 4.7e-211 smc D Required for chromosome condensation and partitioning
LEKHBMCO_00993 9.1e-149 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LEKHBMCO_00994 7e-40 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LEKHBMCO_00995 5e-204 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LEKHBMCO_00996 3.6e-42 rpsP J Belongs to the bacterial ribosomal protein bS16 family
LEKHBMCO_00997 1.1e-26 ylqC S Belongs to the UPF0109 family
LEKHBMCO_00998 1.9e-57 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LEKHBMCO_00999 7.3e-114 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
LEKHBMCO_01000 5.7e-61 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
LEKHBMCO_01001 7e-198 yfnA E amino acid
LEKHBMCO_01002 3e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LEKHBMCO_01003 1.8e-32 rpsT J Binds directly to 16S ribosomal RNA
LEKHBMCO_01004 5.6e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LEKHBMCO_01005 1.2e-115 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LEKHBMCO_01006 1.4e-266 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LEKHBMCO_01007 6.1e-19 S Tetratricopeptide repeat
LEKHBMCO_01008 1.4e-215 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LEKHBMCO_01009 6e-196 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LEKHBMCO_01010 1e-197 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LEKHBMCO_01011 2.3e-249 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LEKHBMCO_01012 1.5e-300 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LEKHBMCO_01013 5e-23 ykzG S Belongs to the UPF0356 family
LEKHBMCO_01014 1.6e-24
LEKHBMCO_01015 2.2e-86 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LEKHBMCO_01016 3.7e-32 1.1.1.27 C L-malate dehydrogenase activity
LEKHBMCO_01017 1.7e-23 yktA S Belongs to the UPF0223 family
LEKHBMCO_01018 9.7e-77 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
LEKHBMCO_01019 0.0 typA T GTP-binding protein TypA
LEKHBMCO_01020 6e-148 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
LEKHBMCO_01021 7e-115 manY G PTS system
LEKHBMCO_01022 3.3e-148 manN G system, mannose fructose sorbose family IID component
LEKHBMCO_01023 1.6e-102 ftsW D Belongs to the SEDS family
LEKHBMCO_01024 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LEKHBMCO_01025 1.1e-17 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
LEKHBMCO_01026 7.2e-74 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
LEKHBMCO_01027 4e-49 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LEKHBMCO_01028 2.4e-131 ylbL T Belongs to the peptidase S16 family
LEKHBMCO_01029 2.2e-96 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
LEKHBMCO_01030 2.2e-30 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LEKHBMCO_01031 6.8e-103 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LEKHBMCO_01032 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LEKHBMCO_01033 2.1e-226 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LEKHBMCO_01034 2.4e-139 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
LEKHBMCO_01035 5.2e-75 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LEKHBMCO_01036 8.5e-234 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
LEKHBMCO_01037 1e-152 purD 6.3.4.13 F Belongs to the GARS family
LEKHBMCO_01038 1.5e-93 S Acyltransferase family
LEKHBMCO_01039 2.2e-194 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LEKHBMCO_01040 3.9e-122 K LysR substrate binding domain
LEKHBMCO_01042 2.2e-20
LEKHBMCO_01043 6.2e-59 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
LEKHBMCO_01044 5.8e-268 argS 6.1.1.19 J Arginyl-tRNA synthetase
LEKHBMCO_01045 1.4e-50 comEA L Competence protein ComEA
LEKHBMCO_01046 2e-69 comEB 3.5.4.12 F ComE operon protein 2
LEKHBMCO_01047 8.1e-152 comEC S Competence protein ComEC
LEKHBMCO_01048 9.3e-104 holA 2.7.7.7 L DNA polymerase III delta subunit
LEKHBMCO_01049 1.3e-113 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LEKHBMCO_01050 3e-137 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
LEKHBMCO_01051 2.8e-118 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
LEKHBMCO_01052 8.1e-94 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
LEKHBMCO_01053 1.5e-228 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
LEKHBMCO_01054 1.8e-36 ypmB S Protein conserved in bacteria
LEKHBMCO_01055 4e-143 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
LEKHBMCO_01056 1e-235 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
LEKHBMCO_01057 5.1e-56 dnaD L DnaD domain protein
LEKHBMCO_01058 4.4e-83 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LEKHBMCO_01059 1.5e-78 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LEKHBMCO_01060 9.6e-126 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LEKHBMCO_01061 1.9e-93 M transferase activity, transferring glycosyl groups
LEKHBMCO_01062 1.4e-83 M Glycosyltransferase sugar-binding region containing DXD motif
LEKHBMCO_01063 1.3e-99 epsJ1 M Glycosyltransferase like family 2
LEKHBMCO_01066 1.1e-115 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
LEKHBMCO_01067 4.7e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
LEKHBMCO_01068 2e-55 yqeY S YqeY-like protein
LEKHBMCO_01070 3.9e-68 xerD L Phage integrase, N-terminal SAM-like domain
LEKHBMCO_01071 1e-106 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LEKHBMCO_01072 1.1e-107 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LEKHBMCO_01073 6.6e-133 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LEKHBMCO_01074 2.9e-276 yfmR S ABC transporter, ATP-binding protein
LEKHBMCO_01075 4.4e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LEKHBMCO_01076 3.2e-57 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LEKHBMCO_01077 2.5e-134 yvgN C Aldo keto reductase
LEKHBMCO_01078 2.4e-35 K helix_turn_helix, mercury resistance
LEKHBMCO_01079 1.3e-102 S Aldo keto reductase
LEKHBMCO_01081 7.2e-79 ypmR E GDSL-like Lipase/Acylhydrolase
LEKHBMCO_01082 5.7e-53 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
LEKHBMCO_01083 3.6e-24 yozE S Belongs to the UPF0346 family
LEKHBMCO_01084 4.7e-133 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LEKHBMCO_01085 8.3e-97 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LEKHBMCO_01086 6.2e-85 dprA LU DNA protecting protein DprA
LEKHBMCO_01087 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LEKHBMCO_01088 9.5e-210 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LEKHBMCO_01089 5.8e-205 G PTS system Galactitol-specific IIC component
LEKHBMCO_01090 2.3e-81 K Bacterial regulatory proteins, tetR family
LEKHBMCO_01091 3.3e-129 yjjC V ATPases associated with a variety of cellular activities
LEKHBMCO_01092 1.1e-202 M Exporter of polyketide antibiotics
LEKHBMCO_01093 4e-100 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
LEKHBMCO_01094 2.3e-34 S Repeat protein
LEKHBMCO_01095 5.8e-277 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LEKHBMCO_01097 3e-119 L Belongs to the 'phage' integrase family
LEKHBMCO_01098 4.7e-14
LEKHBMCO_01100 3.6e-10
LEKHBMCO_01103 1.4e-12 M Host cell surface-exposed lipoprotein
LEKHBMCO_01104 4e-25 polC_1 2.7.7.7 L 3' exoribonuclease, RNase T-like
LEKHBMCO_01105 5.3e-11
LEKHBMCO_01106 8.6e-19 L nuclease
LEKHBMCO_01107 4e-16 E IrrE N-terminal-like domain
LEKHBMCO_01108 2.6e-25 K Helix-turn-helix XRE-family like proteins
LEKHBMCO_01110 3.9e-14 K Helix-turn-helix XRE-family like proteins
LEKHBMCO_01111 5.2e-35 K Phage regulatory protein
LEKHBMCO_01113 4.8e-19 S Domain of unknown function (DUF771)
LEKHBMCO_01118 3.1e-120 L snf2 family
LEKHBMCO_01120 3.1e-18
LEKHBMCO_01121 4.6e-25 L VRR_NUC
LEKHBMCO_01122 2.6e-124 L AAA domain
LEKHBMCO_01123 2.4e-35 S Protein of unknown function (DUF669)
LEKHBMCO_01124 3.1e-176 polB 2.7.7.7 L DNA polymerase elongation subunit (Family B)
LEKHBMCO_01125 5.5e-158 L Phage plasmid primase, P4 family
LEKHBMCO_01129 4.1e-08
LEKHBMCO_01130 5e-28 S HNH endonuclease
LEKHBMCO_01131 1.7e-59 L Belongs to the 'phage' integrase family
LEKHBMCO_01133 9.6e-70 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
LEKHBMCO_01142 9.3e-18
LEKHBMCO_01144 1.7e-22 L HNH nucleases
LEKHBMCO_01145 4.2e-32 L Phage terminase, small subunit
LEKHBMCO_01146 8.5e-211 S Phage Terminase
LEKHBMCO_01147 1.6e-105 S Phage portal protein, HK97 family
LEKHBMCO_01148 8.9e-72 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
LEKHBMCO_01149 3.3e-94 S Phage capsid family
LEKHBMCO_01150 2.6e-12 L Phage gp6-like head-tail connector protein
LEKHBMCO_01152 1.7e-11 S Bacteriophage HK97-gp10, putative tail-component
LEKHBMCO_01154 2.1e-24 S Phage tail tube protein
LEKHBMCO_01156 1.3e-98 M Phage tail tape measure protein TP901
LEKHBMCO_01157 4e-89 S Phage tail protein
LEKHBMCO_01158 1.4e-270 rny D peptidase
LEKHBMCO_01159 4.6e-100 M Prophage endopeptidase tail
LEKHBMCO_01161 1.1e-22 S Calcineurin-like phosphoesterase
LEKHBMCO_01162 1.2e-149 cbiO2 P ABC transporter
LEKHBMCO_01163 1.3e-156 P ABC transporter
LEKHBMCO_01164 1.3e-132 cbiQ P Cobalt transport protein
LEKHBMCO_01165 8.5e-89 2.7.7.65 T phosphorelay sensor kinase activity
LEKHBMCO_01166 0.0 M Cna protein B-type domain
LEKHBMCO_01167 1.1e-258 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
LEKHBMCO_01168 4.6e-79
LEKHBMCO_01169 1.1e-47 L Transposase
LEKHBMCO_01170 2.5e-158 L Transposase
LEKHBMCO_01171 1.4e-10 S Protein of unknown function (DUF3021)
LEKHBMCO_01172 7e-27 K LytTr DNA-binding domain
LEKHBMCO_01173 4.1e-60 cylB V ABC-2 type transporter
LEKHBMCO_01174 2.4e-76 cylA V abc transporter atp-binding protein
LEKHBMCO_01175 1.9e-168 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
LEKHBMCO_01176 2.5e-211 glnP P ABC transporter
LEKHBMCO_01178 6.6e-60 uspA T Universal stress protein family
LEKHBMCO_01179 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
LEKHBMCO_01180 1.1e-25
LEKHBMCO_01181 2.2e-201 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
LEKHBMCO_01182 8e-110 puuD S peptidase C26
LEKHBMCO_01183 5.2e-83 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LEKHBMCO_01184 4.3e-150 lsa S ABC transporter
LEKHBMCO_01185 7.2e-149 mepA V MATE efflux family protein
LEKHBMCO_01186 0.0 L MobA MobL family protein
LEKHBMCO_01187 4.8e-23
LEKHBMCO_01188 4e-41
LEKHBMCO_01189 4.9e-72 S protein conserved in bacteria
LEKHBMCO_01190 4.1e-29 S protein conserved in bacteria
LEKHBMCO_01191 8.3e-27
LEKHBMCO_01192 4.3e-43 relB L Addiction module antitoxin, RelB DinJ family
LEKHBMCO_01193 1.1e-138 S Fic/DOC family
LEKHBMCO_01194 4.9e-25
LEKHBMCO_01195 6.2e-186 repA S Replication initiator protein A
LEKHBMCO_01196 8.5e-35
LEKHBMCO_01197 4.9e-148 D CobQ CobB MinD ParA nucleotide binding domain protein
LEKHBMCO_01198 7.6e-55 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
LEKHBMCO_01199 1.2e-48 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
LEKHBMCO_01200 2.5e-38 S RelB antitoxin
LEKHBMCO_01201 1.1e-288 norB EGP Major Facilitator
LEKHBMCO_01202 3e-99 K Bacterial regulatory proteins, tetR family
LEKHBMCO_01203 3.2e-103 pncA Q Isochorismatase family
LEKHBMCO_01204 1.8e-270 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LEKHBMCO_01205 1.1e-130 3.6.1.13, 3.6.1.55 F NUDIX domain
LEKHBMCO_01206 8.5e-64 V HNH endonuclease
LEKHBMCO_01208 8.3e-164 C Luciferase-like monooxygenase
LEKHBMCO_01209 3.6e-41 K Transcriptional regulator, HxlR family
LEKHBMCO_01210 1.7e-171 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LEKHBMCO_01211 1.2e-103 ydhQ K UbiC transcription regulator-associated domain protein
LEKHBMCO_01212 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
LEKHBMCO_01213 2.4e-82 pncA Q isochorismatase
LEKHBMCO_01214 3.5e-63 3.1.3.73 G phosphoglycerate mutase
LEKHBMCO_01215 1.6e-100 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
LEKHBMCO_01216 5.8e-247 gshR 1.8.1.7 C Glutathione reductase
LEKHBMCO_01217 4.9e-179 proV E ABC transporter, ATP-binding protein
LEKHBMCO_01218 8.5e-182 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LEKHBMCO_01219 9.1e-76 3.1.21.3 V Type I restriction modification DNA specificity domain
LEKHBMCO_01220 1.6e-131 L Belongs to the 'phage' integrase family
LEKHBMCO_01221 1.2e-36 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
LEKHBMCO_01223 9.5e-10 hol S Bacteriophage holin
LEKHBMCO_01224 1.9e-130 lys 3.5.1.104 M Glycosyl hydrolases family 25
LEKHBMCO_01225 1.5e-46
LEKHBMCO_01226 3.3e-64
LEKHBMCO_01227 1.4e-218 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
LEKHBMCO_01231 4.7e-07
LEKHBMCO_01232 3.9e-263 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
LEKHBMCO_01233 1.7e-54 rplI J Binds to the 23S rRNA
LEKHBMCO_01234 1.3e-204 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
LEKHBMCO_01235 5.3e-64 C FMN binding
LEKHBMCO_01236 1.6e-230 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LEKHBMCO_01238 8.7e-157 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LEKHBMCO_01239 3.5e-59 ykhA 3.1.2.20 I Thioesterase superfamily
LEKHBMCO_01240 5.6e-10 S CAAX protease self-immunity
LEKHBMCO_01241 8.1e-81 S Belongs to the UPF0246 family
LEKHBMCO_01242 1.6e-100 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
LEKHBMCO_01243 9.3e-129 yxjG 2.1.1.14 E Cobalamin-independent synthase, Catalytic domain
LEKHBMCO_01244 3.7e-74 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
LEKHBMCO_01245 4.5e-196 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
LEKHBMCO_01246 3.8e-161 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
LEKHBMCO_01247 2.2e-56 3.1.3.48 K Transcriptional regulator
LEKHBMCO_01248 1.5e-197 1.3.5.4 C FMN_bind
LEKHBMCO_01249 6.5e-117 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
LEKHBMCO_01250 2e-201 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
LEKHBMCO_01251 2.8e-139 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
LEKHBMCO_01252 1.9e-80 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
LEKHBMCO_01253 2e-64 2.7.1.191 G PTS system sorbose subfamily IIB component
LEKHBMCO_01254 4.4e-101 G PTS system sorbose-specific iic component
LEKHBMCO_01255 2.4e-123 G PTS system mannose/fructose/sorbose family IID component
LEKHBMCO_01256 2e-39 2.7.1.191 G PTS system fructose IIA component
LEKHBMCO_01257 2.7e-230 malL 3.2.1.10 GH13 G Psort location Cytoplasmic, score
LEKHBMCO_01258 3.1e-112 lacI3 K helix_turn _helix lactose operon repressor
LEKHBMCO_01259 2.8e-135 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
LEKHBMCO_01260 5e-77 hchA S intracellular protease amidase
LEKHBMCO_01261 1.2e-21 K transcriptional regulator
LEKHBMCO_01262 5.6e-150 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
LEKHBMCO_01263 1.5e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
LEKHBMCO_01264 3.3e-21 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
LEKHBMCO_01265 1.5e-251 ctpA 3.6.3.54 P P-type ATPase
LEKHBMCO_01266 5e-66 pgm3 G phosphoglycerate mutase family
LEKHBMCO_01267 8.2e-55 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
LEKHBMCO_01268 1.1e-85 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LEKHBMCO_01269 9.1e-219 yifK E Amino acid permease
LEKHBMCO_01270 1.4e-202 oppA E ABC transporter, substratebinding protein
LEKHBMCO_01271 1e-141 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEKHBMCO_01272 5.8e-170 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEKHBMCO_01273 1.3e-180 oppD P Belongs to the ABC transporter superfamily
LEKHBMCO_01274 4.1e-154 oppF P Belongs to the ABC transporter superfamily
LEKHBMCO_01275 1.2e-15 psiE S Phosphate-starvation-inducible E
LEKHBMCO_01276 2.2e-209 mmuP E amino acid
LEKHBMCO_01277 7.6e-113 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
LEKHBMCO_01278 4.5e-39 K LytTr DNA-binding domain
LEKHBMCO_01279 2.5e-16 S Protein of unknown function (DUF3021)
LEKHBMCO_01280 1.2e-150 yfeX P Peroxidase
LEKHBMCO_01281 1.8e-30 tetR K Transcriptional regulator C-terminal region
LEKHBMCO_01282 3.1e-47 S Short repeat of unknown function (DUF308)
LEKHBMCO_01283 6.2e-53 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LEKHBMCO_01284 8.1e-163 oxlT P Major Facilitator Superfamily
LEKHBMCO_01285 2e-67 ybbL S ABC transporter
LEKHBMCO_01286 1.9e-101 ybbM S Uncharacterised protein family (UPF0014)
LEKHBMCO_01287 4.2e-43 ytcD K HxlR-like helix-turn-helix
LEKHBMCO_01288 6.9e-121 ytbE S reductase
LEKHBMCO_01289 7.5e-72 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEKHBMCO_01291 6.4e-96 XK27_06785 V ABC transporter, ATP-binding protein
LEKHBMCO_01292 3.1e-149 XK27_06780 V ABC transporter permease
LEKHBMCO_01293 1.9e-95 XK27_06780 V ABC transporter permease
LEKHBMCO_01295 5.1e-42 wecD K Acetyltransferase GNAT Family
LEKHBMCO_01296 3.9e-47 hmpT S ECF-type riboflavin transporter, S component
LEKHBMCO_01297 2.1e-69 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
LEKHBMCO_01298 2.9e-09 S SdpI/YhfL protein family
LEKHBMCO_01299 1.7e-111 dat 2.6.1.21 EH PFAM aminotransferase, class IV
LEKHBMCO_01300 3.4e-285 pepO 3.4.24.71 O Peptidase family M13
LEKHBMCO_01301 7.7e-44 thiT S Thiamine transporter protein (Thia_YuaJ)
LEKHBMCO_01302 6.9e-54 K Transcriptional regulator C-terminal region
LEKHBMCO_01303 1.8e-48 jag S R3H domain protein
LEKHBMCO_01304 1.5e-56 ohrR K helix_turn_helix multiple antibiotic resistance protein
LEKHBMCO_01305 2e-31 azlD S Branched-chain amino acid transport protein (AzlD)
LEKHBMCO_01306 2e-76 azlC E branched-chain amino acid
LEKHBMCO_01307 5.5e-59 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
LEKHBMCO_01308 9.4e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
LEKHBMCO_01309 4.7e-294 lai 4.2.1.53 S Myosin-crossreactive antigen
LEKHBMCO_01310 3.8e-33 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
LEKHBMCO_01311 1.1e-193 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
LEKHBMCO_01312 4.1e-75 XK27_02070 S Nitroreductase family
LEKHBMCO_01313 1.7e-111 endA F DNA RNA non-specific endonuclease
LEKHBMCO_01315 5.9e-210 brnQ U Component of the transport system for branched-chain amino acids
LEKHBMCO_01316 6.5e-61 K Bacterial regulatory proteins, tetR family
LEKHBMCO_01317 1.9e-114 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
LEKHBMCO_01318 2e-151 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
LEKHBMCO_01319 9.5e-69 dhaL 2.7.1.121 S Dak2
LEKHBMCO_01320 4e-49 dhaM 2.7.1.121 S PTS system fructose IIA component
LEKHBMCO_01321 8.4e-104 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
LEKHBMCO_01322 9.8e-177 yjcE P Sodium proton antiporter
LEKHBMCO_01323 4e-210 mtlR K Mga helix-turn-helix domain
LEKHBMCO_01324 5.9e-303 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LEKHBMCO_01325 6.1e-188 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
LEKHBMCO_01326 3.8e-34 ponA V the current gene model (or a revised gene model) may contain a frame shift
LEKHBMCO_01328 4.5e-102 tcyB E ABC transporter
LEKHBMCO_01329 4.1e-101 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
LEKHBMCO_01330 1.3e-95 tcyA ET Belongs to the bacterial solute-binding protein 3 family
LEKHBMCO_01331 1.6e-38 K Transcriptional regulator
LEKHBMCO_01332 2.2e-107 terC P Integral membrane protein TerC family
LEKHBMCO_01333 4.2e-261 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
LEKHBMCO_01334 2.8e-65 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEKHBMCO_01335 6.4e-186 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
LEKHBMCO_01336 1.1e-41 gntR1 K Transcriptional regulator, GntR family
LEKHBMCO_01337 8e-96 V ABC transporter, ATP-binding protein
LEKHBMCO_01338 2.5e-08
LEKHBMCO_01339 1.1e-39 ybjQ S Belongs to the UPF0145 family
LEKHBMCO_01340 4.7e-158 manA 5.3.1.8 G mannose-6-phosphate isomerase
LEKHBMCO_01341 1.5e-96 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LEKHBMCO_01342 7.5e-156 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LEKHBMCO_01343 1.8e-141 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LEKHBMCO_01344 1.1e-33
LEKHBMCO_01345 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
LEKHBMCO_01346 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
LEKHBMCO_01347 2.3e-63 srtA 3.4.22.70 M sortase family
LEKHBMCO_01349 1.8e-72 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
LEKHBMCO_01350 7.9e-62 yvdD 3.2.2.10 S Possible lysine decarboxylase
LEKHBMCO_01351 4.5e-218 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
LEKHBMCO_01352 3e-95 L Transposase IS66 family
LEKHBMCO_01353 1.9e-48 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain protein
LEKHBMCO_01354 6.4e-44 XK27_01125 L PFAM IS66 Orf2 family protein
LEKHBMCO_01356 1e-40 sip L Belongs to the 'phage' integrase family
LEKHBMCO_01357 9.7e-69 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEKHBMCO_01358 9.9e-110 pepE 3.4.13.21 E Alpha/beta hydrolase of unknown function (DUF915)
LEKHBMCO_01359 2.7e-72 K Transcriptional regulator
LEKHBMCO_01360 1.1e-124 akr5f 1.1.1.346 S reductase
LEKHBMCO_01361 3.3e-117 EGP Major Facilitator Superfamily
LEKHBMCO_01362 3.7e-168 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
LEKHBMCO_01363 8.1e-280 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
LEKHBMCO_01364 1.3e-212 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LEKHBMCO_01365 2.8e-186 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LEKHBMCO_01367 2.8e-91 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LEKHBMCO_01368 4.8e-44
LEKHBMCO_01369 7.1e-120 ica2 GT2 M Glycosyl transferase family group 2
LEKHBMCO_01370 1.3e-44 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
LEKHBMCO_01371 2.9e-221 mntH P H( )-stimulated, divalent metal cation uptake system
LEKHBMCO_01372 7.1e-59 ypbB 5.1.3.1 S Helix-turn-helix domain
LEKHBMCO_01373 2e-128 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
LEKHBMCO_01374 5.9e-12 M Lysin motif
LEKHBMCO_01375 2e-86 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
LEKHBMCO_01376 7.5e-83 lytH 3.5.1.28 M Ami_3
LEKHBMCO_01377 3.5e-153 phoH T phosphate starvation-inducible protein PhoH
LEKHBMCO_01378 3e-60 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LEKHBMCO_01379 3.6e-30 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
LEKHBMCO_01380 1e-154 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LEKHBMCO_01381 4.5e-90 recO L Involved in DNA repair and RecF pathway recombination
LEKHBMCO_01382 2.6e-07 dltX S D-Ala-teichoic acid biosynthesis protein
LEKHBMCO_01383 3.2e-217 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEKHBMCO_01384 4.1e-175 dltB M MBOAT, membrane-bound O-acyltransferase family
LEKHBMCO_01385 4.9e-29 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEKHBMCO_01386 2e-151 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LEKHBMCO_01387 9.1e-58 arsC 1.20.4.1 T Low molecular weight phosphatase family
LEKHBMCO_01388 2.7e-171 rpsA 1.17.7.4 J Ribosomal protein S1
LEKHBMCO_01389 7.7e-228 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
LEKHBMCO_01390 8.5e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LEKHBMCO_01392 4.8e-23 K Acetyltransferase (GNAT) domain
LEKHBMCO_01393 6.2e-112 natA S Domain of unknown function (DUF4162)
LEKHBMCO_01394 2.3e-85 natB CP ABC-type Na efflux pump, permease component
LEKHBMCO_01395 3.1e-95 EG EamA-like transporter family
LEKHBMCO_01396 1.7e-79 yjjH S Calcineurin-like phosphoesterase
LEKHBMCO_01397 5.7e-188 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LEKHBMCO_01398 2.4e-40 6.3.3.2 S ASCH
LEKHBMCO_01399 7.8e-71 lepB 3.4.21.89 U Signal peptidase, peptidase S26
LEKHBMCO_01400 1.1e-116 degV S EDD domain protein, DegV family
LEKHBMCO_01401 3.1e-40 K Transcriptional regulator
LEKHBMCO_01402 1.2e-196 FbpA K Fibronectin-binding protein
LEKHBMCO_01403 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LEKHBMCO_01404 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LEKHBMCO_01405 3.2e-83 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LEKHBMCO_01406 1e-39 ypaA S Protein of unknown function (DUF1304)
LEKHBMCO_01408 2.4e-309 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
LEKHBMCO_01409 1.9e-167 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LEKHBMCO_01410 0.0 dnaE 2.7.7.7 L DNA polymerase
LEKHBMCO_01411 4.3e-15 S Protein of unknown function (DUF2929)
LEKHBMCO_01412 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
LEKHBMCO_01413 4.3e-203 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LEKHBMCO_01414 3.7e-41 XK27_04120 S Putative amino acid metabolism
LEKHBMCO_01415 2.9e-154 iscS 2.8.1.7 E Aminotransferase class V
LEKHBMCO_01416 7.2e-92 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LEKHBMCO_01418 5.8e-81 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
LEKHBMCO_01419 1.5e-130 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LEKHBMCO_01420 8.5e-161 nhaC C Na H antiporter NhaC
LEKHBMCO_01421 7e-127 corA P CorA-like Mg2+ transporter protein
LEKHBMCO_01422 1.6e-297 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
LEKHBMCO_01423 6.9e-205 hisS 6.1.1.21 J histidyl-tRNA synthetase
LEKHBMCO_01424 3.6e-150 S Tetratricopeptide repeat protein
LEKHBMCO_01425 3.8e-136 EG EamA-like transporter family
LEKHBMCO_01426 4.2e-73 alkD L DNA alkylation repair enzyme
LEKHBMCO_01427 1.9e-183 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
LEKHBMCO_01428 4.8e-103 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LEKHBMCO_01429 6e-78 trmK 2.1.1.217 S SAM-dependent methyltransferase
LEKHBMCO_01430 2.5e-149 EGP Sugar (and other) transporter
LEKHBMCO_01433 1.8e-38
LEKHBMCO_01434 3.8e-256 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
LEKHBMCO_01435 6.2e-21 S Family of unknown function (DUF5322)
LEKHBMCO_01436 1.8e-36 rnhA 3.1.26.4 L Ribonuclease HI
LEKHBMCO_01437 2.7e-173 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
LEKHBMCO_01438 1.1e-35 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LEKHBMCO_01440 2.4e-88 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
LEKHBMCO_01441 4.5e-171 patA 2.6.1.1 E Aminotransferase
LEKHBMCO_01442 8.6e-115 glcR K DeoR C terminal sensor domain
LEKHBMCO_01443 6.3e-144 ppaC 3.6.1.1 C inorganic pyrophosphatase
LEKHBMCO_01444 1.2e-134 K Transcriptional regulator
LEKHBMCO_01445 2.3e-89 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LEKHBMCO_01446 1.5e-84 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LEKHBMCO_01447 5.9e-192 carB 6.3.5.5 F Carbamoyl-phosphate synthase
LEKHBMCO_01448 4.3e-115 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
LEKHBMCO_01449 2.7e-204 pyrP F Permease
LEKHBMCO_01450 1.3e-75 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LEKHBMCO_01451 7.3e-129 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LEKHBMCO_01452 5.2e-43 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LEKHBMCO_01453 6.7e-57 3.1.3.18 J HAD-hyrolase-like
LEKHBMCO_01454 1.7e-54 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LEKHBMCO_01455 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LEKHBMCO_01456 3.1e-77 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LEKHBMCO_01457 5.8e-118 prmA J Ribosomal protein L11 methyltransferase
LEKHBMCO_01458 7.6e-43 XK27_03960 S Protein of unknown function (DUF3013)
LEKHBMCO_01459 1.5e-143 iunH2 3.2.2.1 F nucleoside hydrolase
LEKHBMCO_01460 6.4e-12
LEKHBMCO_01461 6.5e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LEKHBMCO_01462 1.8e-97 udk 2.7.1.48 F Cytidine monophosphokinase
LEKHBMCO_01463 9.3e-129 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LEKHBMCO_01464 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LEKHBMCO_01465 7.4e-173 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LEKHBMCO_01466 9.1e-43 yodB K Transcriptional regulator, HxlR family
LEKHBMCO_01467 2.1e-67 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
LEKHBMCO_01468 5.9e-87 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LEKHBMCO_01471 1.7e-15
LEKHBMCO_01472 5.1e-260 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
LEKHBMCO_01473 1.6e-169 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LEKHBMCO_01474 7.8e-131 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LEKHBMCO_01475 3e-282 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LEKHBMCO_01476 1.5e-76 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
LEKHBMCO_01477 1.9e-96 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LEKHBMCO_01478 1.1e-40 yabR J RNA binding
LEKHBMCO_01479 1e-21 divIC D Septum formation initiator
LEKHBMCO_01480 3.6e-31 yabO J S4 domain protein
LEKHBMCO_01481 1.2e-139 yabM S Polysaccharide biosynthesis protein
LEKHBMCO_01482 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LEKHBMCO_01483 2.2e-75 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LEKHBMCO_01484 4.8e-158 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
LEKHBMCO_01485 2.5e-86 S (CBS) domain
LEKHBMCO_01486 1.4e-141 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LEKHBMCO_01487 3.2e-207 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LEKHBMCO_01488 7.2e-53 perR P Belongs to the Fur family
LEKHBMCO_01489 7.6e-58 S LexA-binding, inner membrane-associated putative hydrolase
LEKHBMCO_01490 7.9e-106 sbcC L Putative exonuclease SbcCD, C subunit
LEKHBMCO_01491 9.8e-115 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
LEKHBMCO_01492 4.4e-34 M LysM domain protein
LEKHBMCO_01493 1.1e-277 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
LEKHBMCO_01494 1.4e-85 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
LEKHBMCO_01495 1.9e-33 ygfC K transcriptional regulator (TetR family)
LEKHBMCO_01496 2.6e-109 hrtB V ABC transporter permease
LEKHBMCO_01497 4e-87 devA 3.6.3.25 V ABC transporter, ATP-binding protein
LEKHBMCO_01498 0.0 helD 3.6.4.12 L DNA helicase
LEKHBMCO_01499 3.1e-246 yjbQ P TrkA C-terminal domain protein
LEKHBMCO_01500 5.7e-28
LEKHBMCO_01501 1.1e-60 rpsI J Belongs to the universal ribosomal protein uS9 family
LEKHBMCO_01502 5.5e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LEKHBMCO_01503 2.5e-125 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LEKHBMCO_01504 2.8e-108 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LEKHBMCO_01505 6.7e-111 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LEKHBMCO_01506 1.8e-100 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LEKHBMCO_01507 4.8e-53 rplQ J Ribosomal protein L17
LEKHBMCO_01508 1.3e-155 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEKHBMCO_01509 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LEKHBMCO_01510 4.4e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LEKHBMCO_01511 2.5e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
LEKHBMCO_01512 4.8e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LEKHBMCO_01513 3.4e-107 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LEKHBMCO_01514 4.4e-207 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LEKHBMCO_01515 1e-67 rplO J Binds to the 23S rRNA
LEKHBMCO_01516 2.1e-22 rpmD J Ribosomal protein L30
LEKHBMCO_01517 1.3e-82 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LEKHBMCO_01518 9.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LEKHBMCO_01519 3.2e-87 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LEKHBMCO_01520 2.5e-65 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LEKHBMCO_01521 4.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LEKHBMCO_01522 1.3e-91 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LEKHBMCO_01523 7e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LEKHBMCO_01524 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LEKHBMCO_01525 8e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LEKHBMCO_01526 9e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
LEKHBMCO_01527 6.2e-73 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LEKHBMCO_01528 5.2e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LEKHBMCO_01529 1.5e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LEKHBMCO_01530 1e-44 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LEKHBMCO_01531 4.1e-142 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LEKHBMCO_01532 2.9e-39 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LEKHBMCO_01533 1e-100 rplD J Forms part of the polypeptide exit tunnel
LEKHBMCO_01534 4.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LEKHBMCO_01535 2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
LEKHBMCO_01536 4.3e-167 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LEKHBMCO_01537 2.5e-78 K rpiR family
LEKHBMCO_01538 2.6e-54 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
LEKHBMCO_01539 3.2e-146 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
LEKHBMCO_01540 6.5e-21 K Acetyltransferase (GNAT) domain
LEKHBMCO_01541 9e-184 steT E amino acid
LEKHBMCO_01542 9.6e-78 glnP P ABC transporter permease
LEKHBMCO_01543 1.2e-85 gluC P ABC transporter permease
LEKHBMCO_01544 1.9e-99 glnH ET ABC transporter
LEKHBMCO_01545 3.7e-102 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
LEKHBMCO_01546 1.3e-09
LEKHBMCO_01547 5e-98
LEKHBMCO_01548 3e-12 3.2.1.14 GH18
LEKHBMCO_01549 5.4e-53 zur P Belongs to the Fur family
LEKHBMCO_01550 6.3e-212 yfnA E Amino Acid
LEKHBMCO_01551 9.6e-251 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LEKHBMCO_01552 0.0 L Helicase C-terminal domain protein
LEKHBMCO_01553 2.7e-79 ptp2 3.1.3.48 T Tyrosine phosphatase family
LEKHBMCO_01554 4.6e-180 yhdP S Transporter associated domain
LEKHBMCO_01555 4.8e-26
LEKHBMCO_01556 3.7e-75 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LEKHBMCO_01557 1.3e-131 bacI V MacB-like periplasmic core domain
LEKHBMCO_01558 9.6e-97 V ABC transporter
LEKHBMCO_01559 2.2e-63 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LEKHBMCO_01560 1.4e-156 gmuE 2.7.1.2, 2.7.1.4 GK ROK family
LEKHBMCO_01561 3.6e-140 V MatE
LEKHBMCO_01562 1.6e-43 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEKHBMCO_01563 5e-87 S Alpha beta hydrolase
LEKHBMCO_01564 1.6e-94 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LEKHBMCO_01565 2.5e-174 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
LEKHBMCO_01566 4.6e-112 argE 3.5.1.18 E Peptidase dimerisation domain
LEKHBMCO_01567 1.1e-101 IQ Enoyl-(Acyl carrier protein) reductase
LEKHBMCO_01568 2.5e-33 XK27_01315 S Protein of unknown function (DUF2829)
LEKHBMCO_01569 4.3e-54 queT S QueT transporter
LEKHBMCO_01571 7.3e-65 degV S Uncharacterised protein, DegV family COG1307
LEKHBMCO_01572 2e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LEKHBMCO_01573 2.7e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LEKHBMCO_01574 1.9e-34 trxA O Belongs to the thioredoxin family
LEKHBMCO_01575 4.9e-87 S Sucrose-6F-phosphate phosphohydrolase
LEKHBMCO_01576 3.2e-121 brpA K Cell envelope-like function transcriptional attenuator common domain protein
LEKHBMCO_01577 2.8e-49 S Threonine/Serine exporter, ThrE
LEKHBMCO_01578 1.3e-81 thrE S Putative threonine/serine exporter
LEKHBMCO_01579 3.1e-27 cspC K Cold shock protein
LEKHBMCO_01580 8.3e-90 sirR K Helix-turn-helix diphteria tox regulatory element
LEKHBMCO_01581 2.9e-93 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
LEKHBMCO_01582 5.4e-23
LEKHBMCO_01583 5.6e-59 3.6.1.27 I phosphatase
LEKHBMCO_01584 3.1e-25
LEKHBMCO_01585 2.4e-65 I alpha/beta hydrolase fold
LEKHBMCO_01586 1.3e-38 azlD S branched-chain amino acid
LEKHBMCO_01587 1.1e-104 azlC E AzlC protein
LEKHBMCO_01588 1.6e-17
LEKHBMCO_01589 1.3e-119 xth 3.1.11.2 L exodeoxyribonuclease III
LEKHBMCO_01590 3.8e-99 V domain protein
LEKHBMCO_01591 3.9e-10
LEKHBMCO_01595 6.2e-43 S virion core protein, lumpy skin disease virus
LEKHBMCO_01596 2.1e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LEKHBMCO_01597 1.3e-173 malY 4.4.1.8 E Aminotransferase, class I
LEKHBMCO_01598 5.3e-118 K AI-2E family transporter
LEKHBMCO_01599 4e-61 EG EamA-like transporter family
LEKHBMCO_01600 3.9e-76 L haloacid dehalogenase-like hydrolase
LEKHBMCO_01601 5.8e-117 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
LEKHBMCO_01602 9.1e-67 1.5.1.38 S NADPH-dependent FMN reductase
LEKHBMCO_01609 5.1e-08
LEKHBMCO_01614 4.2e-145 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LEKHBMCO_01615 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
LEKHBMCO_01616 1.3e-279 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LEKHBMCO_01617 9.3e-161 camS S sex pheromone
LEKHBMCO_01618 7.6e-38 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LEKHBMCO_01619 4e-233 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LEKHBMCO_01620 2.8e-255 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LEKHBMCO_01621 9.8e-146 yegS 2.7.1.107 G Lipid kinase
LEKHBMCO_01622 9.9e-210 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LEKHBMCO_01623 1.4e-121 L Mrr N-terminal domain
LEKHBMCO_01624 1.3e-17
LEKHBMCO_01625 1.3e-75 K phage regulatory protein, rha family
LEKHBMCO_01626 3e-22
LEKHBMCO_01627 4.1e-16
LEKHBMCO_01628 9.1e-78 L AAA domain
LEKHBMCO_01629 5.4e-19 K Cro/C1-type HTH DNA-binding domain
LEKHBMCO_01630 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
LEKHBMCO_01631 6.5e-162 hsdM 2.1.1.72 V cog cog0286
LEKHBMCO_01632 3.2e-37 hsdM 2.1.1.72 V type I restriction-modification system
LEKHBMCO_01633 4.5e-86 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain protein
LEKHBMCO_01634 8.3e-126 S Bacteriophage abortive infection AbiH
LEKHBMCO_01637 1.6e-174 spoVK O ATPase family associated with various cellular activities (AAA)
LEKHBMCO_01638 3.5e-50 K Cro/C1-type HTH DNA-binding domain
LEKHBMCO_01640 5.2e-65 S Acetyltransferase (GNAT) domain
LEKHBMCO_01641 5.1e-72 ywlG S Belongs to the UPF0340 family
LEKHBMCO_01642 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
LEKHBMCO_01643 2.8e-96 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LEKHBMCO_01644 8.8e-58 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LEKHBMCO_01645 8.2e-177 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
LEKHBMCO_01646 2e-14 ybaN S Protein of unknown function (DUF454)
LEKHBMCO_01647 3.9e-238 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LEKHBMCO_01648 5.5e-200 frdC 1.3.5.4 C FAD binding domain
LEKHBMCO_01649 5.3e-206 yflS P Sodium:sulfate symporter transmembrane region
LEKHBMCO_01650 7.9e-36 yncA 2.3.1.79 S Maltose acetyltransferase
LEKHBMCO_01651 1.4e-162 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LEKHBMCO_01652 8.4e-60 dedA 3.1.3.1 S SNARE associated Golgi protein
LEKHBMCO_01653 1.9e-95 ypuA S Protein of unknown function (DUF1002)
LEKHBMCO_01655 1.4e-113 3.2.1.18 GH33 M Rib/alpha-like repeat
LEKHBMCO_01656 2.1e-116 3.2.1.18 GH33 M Rib/alpha-like repeat
LEKHBMCO_01657 8.1e-44 K Copper transport repressor CopY TcrY
LEKHBMCO_01658 6.1e-60 T Belongs to the universal stress protein A family
LEKHBMCO_01659 5.9e-41 K Bacterial regulatory proteins, tetR family
LEKHBMCO_01660 1.1e-56 K transcriptional
LEKHBMCO_01661 1.8e-71 mleR K LysR family
LEKHBMCO_01662 1.7e-248 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
LEKHBMCO_01663 1.8e-125 mleP S Sodium Bile acid symporter family
LEKHBMCO_01664 5.5e-64 S ECF transporter, substrate-specific component
LEKHBMCO_01665 1.6e-61 acmC 3.2.1.96 NU mannosyl-glycoprotein
LEKHBMCO_01666 9.7e-74 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LEKHBMCO_01667 6.3e-193 pbuX F xanthine permease
LEKHBMCO_01668 1.7e-35 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
LEKHBMCO_01669 4.5e-254 topB 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
LEKHBMCO_01670 2.5e-94 yjbM 2.7.6.5 S RelA SpoT domain protein
LEKHBMCO_01671 1.3e-116 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LEKHBMCO_01672 7.6e-94 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
LEKHBMCO_01673 6.1e-159 mgtE P Acts as a magnesium transporter
LEKHBMCO_01675 1.7e-40
LEKHBMCO_01676 9.7e-35 K GNAT family
LEKHBMCO_01677 6.4e-209 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
LEKHBMCO_01678 5.5e-221 gdhA 1.4.1.4 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
LEKHBMCO_01679 4.9e-42 O ADP-ribosylglycohydrolase
LEKHBMCO_01680 3.6e-220 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
LEKHBMCO_01681 1.1e-265 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LEKHBMCO_01682 1.2e-160 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LEKHBMCO_01683 1.4e-119 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
LEKHBMCO_01684 1.4e-193 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
LEKHBMCO_01685 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
LEKHBMCO_01686 3.6e-175 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
LEKHBMCO_01687 2e-24 S Domain of unknown function (DUF4828)
LEKHBMCO_01688 3.5e-127 mocA S Oxidoreductase
LEKHBMCO_01689 5.2e-160 yfmL L DEAD DEAH box helicase
LEKHBMCO_01690 2e-20 S Domain of unknown function (DUF3284)
LEKHBMCO_01692 2.3e-279 kup P Transport of potassium into the cell
LEKHBMCO_01693 4.2e-101 malR K Transcriptional regulator, LacI family
LEKHBMCO_01694 4.3e-213 malT G Transporter, major facilitator family protein
LEKHBMCO_01695 2.9e-78 galM 5.1.3.3 G Aldose 1-epimerase
LEKHBMCO_01696 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
LEKHBMCO_01697 4.9e-85 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
LEKHBMCO_01698 3e-266 E Amino acid permease
LEKHBMCO_01699 3.5e-182 pepS E Thermophilic metalloprotease (M29)
LEKHBMCO_01700 9.3e-169 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LEKHBMCO_01701 3.1e-70 K Sugar-specific transcriptional regulator TrmB
LEKHBMCO_01702 1.7e-122 S Sulfite exporter TauE/SafE
LEKHBMCO_01703 5.2e-120 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
LEKHBMCO_01704 0.0 S Bacterial membrane protein YfhO
LEKHBMCO_01705 8.7e-53 gtcA S Teichoic acid glycosylation protein
LEKHBMCO_01706 5.1e-54 fld C Flavodoxin
LEKHBMCO_01707 3.5e-143 map 3.4.11.18 E Methionine Aminopeptidase
LEKHBMCO_01708 1.2e-152 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
LEKHBMCO_01709 2.8e-12 mltD CBM50 M Lysin motif
LEKHBMCO_01710 2.9e-93 yihY S Belongs to the UPF0761 family
LEKHBMCO_01711 9e-120 G Bacterial extracellular solute-binding protein
LEKHBMCO_01712 3e-79 baeR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LEKHBMCO_01713 1.6e-100 baeS T Histidine kinase
LEKHBMCO_01714 7e-80 rbsB G sugar-binding domain protein
LEKHBMCO_01715 9e-152 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
LEKHBMCO_01716 6.4e-116 manY G PTS system sorbose-specific iic component
LEKHBMCO_01717 2.1e-147 manN G system, mannose fructose sorbose family IID component
LEKHBMCO_01718 3.2e-52 manO S Domain of unknown function (DUF956)
LEKHBMCO_01719 8.2e-72 mltD CBM50 M NlpC P60 family protein
LEKHBMCO_01720 4.7e-130 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LEKHBMCO_01721 1.6e-163 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEKHBMCO_01722 2.4e-75 ung2 3.2.2.27 L Uracil-DNA glycosylase
LEKHBMCO_01723 1e-47 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
LEKHBMCO_01724 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
LEKHBMCO_01725 3e-106 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LEKHBMCO_01726 6.5e-37 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LEKHBMCO_01727 2e-46 S CRISPR-associated protein (Cas_Csn2)
LEKHBMCO_01728 7.8e-38 K transcriptional regulator PadR family
LEKHBMCO_01729 3.2e-19 XK27_06920 S Protein of unknown function (DUF1700)
LEKHBMCO_01730 1.2e-15 S Putative adhesin
LEKHBMCO_01731 2.2e-16 pspC KT PspC domain
LEKHBMCO_01733 5.1e-13 S Enterocin A Immunity
LEKHBMCO_01734 4e-236 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LEKHBMCO_01735 1.3e-260 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
LEKHBMCO_01736 4.3e-100 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
LEKHBMCO_01737 1.1e-166 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
LEKHBMCO_01738 1.5e-120 potB P ABC transporter permease
LEKHBMCO_01739 4.5e-104 potC U Binding-protein-dependent transport system inner membrane component
LEKHBMCO_01740 1.3e-159 potD P ABC transporter
LEKHBMCO_01741 3.5e-132 ABC-SBP S ABC transporter
LEKHBMCO_01742 3.3e-113 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
LEKHBMCO_01743 6.7e-107 XK27_08845 S ABC transporter, ATP-binding protein
LEKHBMCO_01744 2.8e-66 M ErfK YbiS YcfS YnhG
LEKHBMCO_01745 1.2e-53 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LEKHBMCO_01746 4.2e-224 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LEKHBMCO_01747 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LEKHBMCO_01748 1.2e-102 pgm3 G phosphoglycerate mutase
LEKHBMCO_01749 4.7e-56 S CAAX protease self-immunity
LEKHBMCO_01750 2.2e-47 C Flavodoxin
LEKHBMCO_01751 9.7e-60 yphH S Cupin domain
LEKHBMCO_01752 3.6e-46 yphJ 4.1.1.44 S decarboxylase
LEKHBMCO_01753 2.9e-143 E methionine synthase, vitamin-B12 independent
LEKHBMCO_01754 7.4e-107 metQ1 P Belongs to the nlpA lipoprotein family
LEKHBMCO_01755 1.5e-149 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LEKHBMCO_01756 2.7e-70 metI P ABC transporter permease
LEKHBMCO_01757 3.3e-134 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
LEKHBMCO_01758 3e-84 drgA C nitroreductase
LEKHBMCO_01759 2.5e-83 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
LEKHBMCO_01760 1.7e-106 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
LEKHBMCO_01761 8.1e-172 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
LEKHBMCO_01762 4.8e-264 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
LEKHBMCO_01764 2.3e-150 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LEKHBMCO_01765 2.4e-31 metI U ABC transporter permease
LEKHBMCO_01766 2.5e-128 metQ M Belongs to the nlpA lipoprotein family
LEKHBMCO_01767 1.8e-53 S Protein of unknown function (DUF4256)
LEKHBMCO_01770 4.7e-178 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
LEKHBMCO_01771 5.7e-167 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
LEKHBMCO_01772 4.5e-180 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LEKHBMCO_01773 4e-230 lpdA 1.8.1.4 C Dehydrogenase
LEKHBMCO_01774 2.1e-148 lplA 6.3.1.20 H Lipoate-protein ligase
LEKHBMCO_01775 9.2e-56 S Protein of unknown function (DUF975)
LEKHBMCO_01776 5.7e-78 E GDSL-like Lipase/Acylhydrolase family
LEKHBMCO_01777 1.4e-38
LEKHBMCO_01778 4.1e-27 gcvR T Belongs to the UPF0237 family
LEKHBMCO_01779 2.1e-220 XK27_08635 S UPF0210 protein
LEKHBMCO_01780 4.5e-87 fruR K DeoR C terminal sensor domain
LEKHBMCO_01781 4.1e-151 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
LEKHBMCO_01782 4.9e-16 fruA 2.7.1.202 GT Phosphotransferase System
LEKHBMCO_01783 5.5e-144 dapE 3.5.1.18 E Peptidase dimerisation domain
LEKHBMCO_01784 1e-149 E glutamate:sodium symporter activity
LEKHBMCO_01785 1.2e-145 Q Imidazolonepropionase and related amidohydrolases
LEKHBMCO_01786 9.1e-50 cps3F
LEKHBMCO_01787 3e-82 S Membrane
LEKHBMCO_01788 1.8e-254 E Amino acid permease
LEKHBMCO_01789 7.3e-99 cadA P P-type ATPase
LEKHBMCO_01790 7.8e-107 cadA P P-type ATPase
LEKHBMCO_01791 6.4e-114 degV S EDD domain protein, DegV family
LEKHBMCO_01792 1.1e-148 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
LEKHBMCO_01793 1.2e-56 yfeJ 6.3.5.2 F glutamine amidotransferase
LEKHBMCO_01794 7.2e-27 ydiI Q Thioesterase superfamily
LEKHBMCO_01795 1.5e-144 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LEKHBMCO_01796 3.5e-141 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
LEKHBMCO_01797 5.6e-82 S L,D-transpeptidase catalytic domain
LEKHBMCO_01798 8.8e-166 EGP Major facilitator Superfamily
LEKHBMCO_01799 2.3e-21 K helix_turn_helix multiple antibiotic resistance protein
LEKHBMCO_01800 1.7e-225 pipD E Dipeptidase
LEKHBMCO_01801 4.1e-126 brpA K Cell envelope-like function transcriptional attenuator common domain protein
LEKHBMCO_01802 2.6e-32 ywjH S Protein of unknown function (DUF1634)
LEKHBMCO_01803 6.5e-119 yxaA S membrane transporter protein
LEKHBMCO_01804 1.7e-82 lysR5 K LysR substrate binding domain
LEKHBMCO_01805 8e-56 lssY 3.6.1.27 I phosphatidate phosphatase activity
LEKHBMCO_01806 3.2e-14 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LEKHBMCO_01807 3.3e-271 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
LEKHBMCO_01808 2.3e-69 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
LEKHBMCO_01809 1.9e-243 lysP E amino acid
LEKHBMCO_01810 4.8e-190 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LEKHBMCO_01822 2.1e-07
LEKHBMCO_01824 2.2e-131 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
LEKHBMCO_01825 1.4e-186 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LEKHBMCO_01826 3.7e-159 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
LEKHBMCO_01827 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
LEKHBMCO_01828 2.5e-119 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LEKHBMCO_01830 1.6e-55 ctsR K Belongs to the CtsR family
LEKHBMCO_01831 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
LEKHBMCO_01832 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEKHBMCO_01833 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEKHBMCO_01834 3.3e-23 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
LEKHBMCO_01835 6.1e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LEKHBMCO_01836 1.3e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LEKHBMCO_01837 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LEKHBMCO_01838 1.3e-91 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
LEKHBMCO_01839 1.2e-89 patB 4.4.1.8 E Aminotransferase, class I
LEKHBMCO_01840 2.5e-113 K response regulator
LEKHBMCO_01841 3.3e-142 hpk31 2.7.13.3 T Histidine kinase
LEKHBMCO_01842 2.2e-90 lacX 5.1.3.3 G Aldose 1-epimerase
LEKHBMCO_01843 1.9e-20 G Transporter, major facilitator family protein
LEKHBMCO_01844 4.3e-116 G Transporter, major facilitator family protein
LEKHBMCO_01845 7e-224 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LEKHBMCO_01846 1.1e-244 yhcA V ABC transporter, ATP-binding protein
LEKHBMCO_01847 5.8e-35 K Bacterial regulatory proteins, tetR family
LEKHBMCO_01848 4.6e-37 lmrA V ABC transporter, ATP-binding protein
LEKHBMCO_01849 1.6e-172 lmrA V ABC transporter, ATP-binding protein
LEKHBMCO_01850 3.3e-253 yfiC V ABC transporter
LEKHBMCO_01852 3.2e-45 yjcF K protein acetylation
LEKHBMCO_01853 1.1e-54 L phosphatase homologous to the C-terminal domain of histone macroH2A1
LEKHBMCO_01854 1.5e-71 lemA S LemA family
LEKHBMCO_01855 1.3e-114 htpX O Belongs to the peptidase M48B family
LEKHBMCO_01857 2.3e-272 helD 3.6.4.12 L DNA helicase
LEKHBMCO_01858 9.3e-128 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LEKHBMCO_01859 2.3e-171 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
LEKHBMCO_01860 9.4e-103 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
LEKHBMCO_01861 8.4e-83 ybhF_2 V abc transporter atp-binding protein
LEKHBMCO_01862 3.5e-104 ybhR V ABC transporter
LEKHBMCO_01863 8.7e-31 K Transcriptional regulator
LEKHBMCO_01864 7.2e-43 VPA1512 ET Bacterial extracellular solute-binding proteins, family 3
LEKHBMCO_01865 2.1e-153 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
LEKHBMCO_01866 4.3e-127
LEKHBMCO_01867 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LEKHBMCO_01868 8.3e-105 tatD L hydrolase, TatD family
LEKHBMCO_01869 1.7e-86 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LEKHBMCO_01870 7.5e-134 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LEKHBMCO_01871 1.2e-22 veg S Biofilm formation stimulator VEG
LEKHBMCO_01872 1.7e-90 S Alpha/beta hydrolase of unknown function (DUF915)
LEKHBMCO_01873 4.2e-134 arcT 2.6.1.1 E Cys/Met metabolism PLP-dependent enzyme
LEKHBMCO_01874 6.6e-46 argR K Regulates arginine biosynthesis genes
LEKHBMCO_01875 2.8e-117 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LEKHBMCO_01876 1.3e-155 amtB P ammonium transporter
LEKHBMCO_01878 9.2e-84 sip L Belongs to the 'phage' integrase family
LEKHBMCO_01880 2e-61
LEKHBMCO_01881 8.8e-38 XK27_10050 K Peptidase S24-like
LEKHBMCO_01885 1.5e-16
LEKHBMCO_01888 1.7e-14 cro K Helix-turn-helix XRE-family like proteins
LEKHBMCO_01889 4.6e-81 S DNA binding
LEKHBMCO_01894 1.7e-54 S Putative HNHc nuclease
LEKHBMCO_01895 2.8e-28 S Phage replisome organizer, N-terminal domain protein
LEKHBMCO_01898 1.6e-25
LEKHBMCO_01899 2.2e-70
LEKHBMCO_01907 2.4e-32 arpU S Phage transcriptional regulator, ArpU family
LEKHBMCO_01908 3.1e-54 V Abi-like protein
LEKHBMCO_01909 4.5e-08
LEKHBMCO_01913 8.4e-45 S HicB_like antitoxin of bacterial toxin-antitoxin system
LEKHBMCO_01914 7.1e-12 S HicA toxin of bacterial toxin-antitoxin,
LEKHBMCO_01915 4.4e-21
LEKHBMCO_01916 1.8e-87 L HNH nucleases
LEKHBMCO_01917 2.3e-78 L Phage terminase, small subunit
LEKHBMCO_01918 0.0 S Phage Terminase
LEKHBMCO_01920 3.2e-193 S Phage portal protein
LEKHBMCO_01921 1.8e-114 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
LEKHBMCO_01922 1e-197 S Phage capsid family
LEKHBMCO_01923 7e-21 S Phage gp6-like head-tail connector protein
LEKHBMCO_01924 4.2e-51 S Phage head-tail joining protein
LEKHBMCO_01925 4.1e-53 S Bacteriophage HK97-gp10, putative tail-component
LEKHBMCO_01926 3e-55 S Protein of unknown function (DUF806)
LEKHBMCO_01927 3.5e-78 S Phage tail tube protein
LEKHBMCO_01928 1.3e-16 S Phage tail assembly chaperone proteins, TAC
LEKHBMCO_01930 1.3e-283 M Phage tail tape measure protein TP901
LEKHBMCO_01931 6e-77 S Phage tail protein
LEKHBMCO_01932 1.1e-120 rny D peptidase
LEKHBMCO_01934 1.5e-21
LEKHBMCO_01939 6.5e-20 S Bacteriophage holin of superfamily 6 (Holin_LLH)
LEKHBMCO_01940 2.4e-98 M hydrolase, family 25
LEKHBMCO_01941 2.2e-201 argH 4.3.2.1 E argininosuccinate lyase
LEKHBMCO_01942 1.9e-196 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
LEKHBMCO_01943 6.2e-152 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
LEKHBMCO_01944 2.2e-126 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEKHBMCO_01945 2.5e-104 pfoS S Phosphotransferase system, EIIC
LEKHBMCO_01946 3.9e-185 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LEKHBMCO_01947 6.6e-53 adhR K helix_turn_helix, mercury resistance
LEKHBMCO_01948 5.2e-137 purR 2.4.2.7 F pur operon repressor
LEKHBMCO_01949 2.1e-46 EGP Transmembrane secretion effector
LEKHBMCO_01950 1.1e-192 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LEKHBMCO_01951 2.5e-167 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LEKHBMCO_01952 7.7e-19 rimL 1.1.1.25 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LEKHBMCO_01953 7.6e-112 dkg S reductase
LEKHBMCO_01954 1.1e-23
LEKHBMCO_01955 1e-78 2.4.2.3 F Phosphorylase superfamily
LEKHBMCO_01956 2e-289 ybiT S ABC transporter, ATP-binding protein
LEKHBMCO_01957 1.1e-62 bCE_4747 S Beta-lactamase superfamily domain
LEKHBMCO_01958 1.9e-98 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LEKHBMCO_01959 1.6e-125 S overlaps another CDS with the same product name
LEKHBMCO_01960 2.2e-86 S overlaps another CDS with the same product name
LEKHBMCO_01962 3e-56 spoVK O ATPase family associated with various cellular activities (AAA)
LEKHBMCO_01963 2.3e-22
LEKHBMCO_01964 1.1e-39 L COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
LEKHBMCO_01966 1.3e-63
LEKHBMCO_01967 2e-105 ydcZ S Putative inner membrane exporter, YdcZ
LEKHBMCO_01968 7.5e-88 S hydrolase
LEKHBMCO_01969 7.7e-80 ywfO S HD domain protein
LEKHBMCO_01970 2.4e-112 ywfO S HD domain protein
LEKHBMCO_01971 2e-86 yfeJ 6.3.5.2 F glutamine amidotransferase
LEKHBMCO_01972 1.8e-32 ywiB S Domain of unknown function (DUF1934)
LEKHBMCO_01973 1e-41 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LEKHBMCO_01974 1.2e-288 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LEKHBMCO_01976 1e-200 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LEKHBMCO_01977 5.3e-189 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LEKHBMCO_01978 3.6e-41 rpmE2 J Ribosomal protein L31
LEKHBMCO_01979 6.3e-61
LEKHBMCO_01980 6.4e-257 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
LEKHBMCO_01982 1.8e-78 S Cell surface protein
LEKHBMCO_01984 1.2e-180 pbuG S permease
LEKHBMCO_01985 2.6e-84 dacA 3.4.16.4 M Belongs to the peptidase S11 family
LEKHBMCO_01987 7.7e-61 M ErfK YbiS YcfS YnhG
LEKHBMCO_01988 4.9e-65 S Uncharacterized protein conserved in bacteria (DUF2263)
LEKHBMCO_01989 4.1e-179 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LEKHBMCO_01990 3.4e-208 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LEKHBMCO_01991 1.6e-30 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LEKHBMCO_01992 4.8e-146 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LEKHBMCO_01993 5.4e-13
LEKHBMCO_01994 3.4e-48 ndoA L Toxic component of a toxin-antitoxin (TA) module
LEKHBMCO_01995 1.5e-91 yunF F Protein of unknown function DUF72
LEKHBMCO_01996 6.6e-156 nrnB S DHHA1 domain
LEKHBMCO_01997 1.3e-43 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
LEKHBMCO_01998 7.6e-60
LEKHBMCO_01999 2.3e-48 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain (presumed)
LEKHBMCO_02000 7e-23 S Cytochrome B5
LEKHBMCO_02001 1.1e-19 yvrI K RNA polymerase sigma factor, sigma-70 family
LEKHBMCO_02002 2.9e-68 recX 2.4.1.337 GT4 S Regulatory protein RecX
LEKHBMCO_02003 9.4e-192 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LEKHBMCO_02004 2.6e-97 ygaC J Belongs to the UPF0374 family
LEKHBMCO_02005 3.4e-91 yueF S AI-2E family transporter
LEKHBMCO_02006 6.5e-158 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
LEKHBMCO_02007 1.4e-108 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
LEKHBMCO_02008 5.2e-279 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LEKHBMCO_02009 0.0 lacL 3.2.1.23 G -beta-galactosidase
LEKHBMCO_02010 4e-289 lacS G Transporter
LEKHBMCO_02011 5.9e-111 galR K Transcriptional regulator
LEKHBMCO_02012 7.7e-179 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LEKHBMCO_02013 2.3e-163 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LEKHBMCO_02014 1.6e-200 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
LEKHBMCO_02015 0.0 rafA 3.2.1.22 G alpha-galactosidase
LEKHBMCO_02016 2.9e-105 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
LEKHBMCO_02017 6.6e-23 XK27_09445 S Domain of unknown function (DUF1827)
LEKHBMCO_02018 0.0 clpE O Belongs to the ClpA ClpB family
LEKHBMCO_02019 1.5e-15
LEKHBMCO_02020 9.7e-37 ptsH G phosphocarrier protein HPR
LEKHBMCO_02021 1.2e-284 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LEKHBMCO_02022 8.8e-162 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
LEKHBMCO_02023 5.4e-128 cpoA GT4 M Glycosyltransferase, group 1 family protein
LEKHBMCO_02024 1.7e-129 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LEKHBMCO_02025 6.8e-26 ykuJ S Protein of unknown function (DUF1797)
LEKHBMCO_02026 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)