ORF_ID e_value Gene_name EC_number CAZy COGs Description
DBHLEIBD_00002 1.6e-197 dtpT U amino acid peptide transporter
DBHLEIBD_00003 1.1e-07
DBHLEIBD_00005 1e-89 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DBHLEIBD_00006 4.9e-96 gntR1 K UbiC transcription regulator-associated domain protein
DBHLEIBD_00007 1.4e-90 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
DBHLEIBD_00008 9.5e-243 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DBHLEIBD_00009 1.8e-129 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
DBHLEIBD_00010 3.7e-251 yhgF K Tex-like protein N-terminal domain protein
DBHLEIBD_00011 3e-43 ydcK S Belongs to the SprT family
DBHLEIBD_00013 3.5e-116 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DBHLEIBD_00014 1e-128 mleP2 S Sodium Bile acid symporter family
DBHLEIBD_00015 2.9e-85 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DBHLEIBD_00016 1e-33 S Enterocin A Immunity
DBHLEIBD_00017 5.8e-223 pepC 3.4.22.40 E Peptidase C1-like family
DBHLEIBD_00018 8.1e-18 HA62_12640 S GCN5-related N-acetyl-transferase
DBHLEIBD_00019 4e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
DBHLEIBD_00020 3.5e-223 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DBHLEIBD_00021 8.2e-154 yacL S domain protein
DBHLEIBD_00022 2.9e-247 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DBHLEIBD_00023 1.1e-206 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
DBHLEIBD_00024 3.8e-56 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DBHLEIBD_00025 1.2e-108 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DBHLEIBD_00026 7e-71 yacP S YacP-like NYN domain
DBHLEIBD_00027 3.1e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
DBHLEIBD_00028 2.6e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
DBHLEIBD_00029 7.7e-84 nusG K Participates in transcription elongation, termination and antitermination
DBHLEIBD_00030 5e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DBHLEIBD_00031 1.6e-115 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
DBHLEIBD_00032 1.7e-74 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DBHLEIBD_00033 2.6e-48 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
DBHLEIBD_00034 1.6e-55
DBHLEIBD_00035 2.7e-301 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DBHLEIBD_00036 1e-160 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DBHLEIBD_00037 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DBHLEIBD_00038 4.8e-45 nrdI F NrdI Flavodoxin like
DBHLEIBD_00039 1.2e-27 nrdH O Glutaredoxin
DBHLEIBD_00040 6.4e-76 rsmC 2.1.1.172 J Methyltransferase
DBHLEIBD_00041 3.3e-62 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
DBHLEIBD_00042 4.6e-212 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DBHLEIBD_00043 7e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DBHLEIBD_00044 2.2e-97 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DBHLEIBD_00045 7.1e-29 yaaL S Protein of unknown function (DUF2508)
DBHLEIBD_00046 8.1e-66 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DBHLEIBD_00047 3e-83 holB 2.7.7.7 L DNA polymerase III
DBHLEIBD_00048 1.4e-40 yabA L Involved in initiation control of chromosome replication
DBHLEIBD_00049 2.1e-96 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DBHLEIBD_00050 7.2e-82 fat 3.1.2.21 I Acyl-ACP thioesterase
DBHLEIBD_00051 1.2e-140 ansA 3.5.1.1 EJ Asparaginase
DBHLEIBD_00052 8.2e-70 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
DBHLEIBD_00053 1.1e-28 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
DBHLEIBD_00054 9.2e-160 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DBHLEIBD_00055 2.6e-256 uup S ABC transporter, ATP-binding protein
DBHLEIBD_00056 9.7e-99 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DBHLEIBD_00057 1.3e-31 S CAAX protease self-immunity
DBHLEIBD_00058 2.4e-33 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DBHLEIBD_00059 1.1e-271 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
DBHLEIBD_00060 5.7e-269 aha1 P COG COG0474 Cation transport ATPase
DBHLEIBD_00061 4.9e-297 ydaO E amino acid
DBHLEIBD_00062 1.6e-157 tagO 2.7.8.33, 2.7.8.35 M transferase
DBHLEIBD_00063 1.9e-128 comFA L Helicase C-terminal domain protein
DBHLEIBD_00064 3e-50 comFC S Competence protein
DBHLEIBD_00065 2.1e-81 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DBHLEIBD_00066 9.1e-95 yeaN P Major Facilitator Superfamily
DBHLEIBD_00067 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DBHLEIBD_00068 4.9e-164 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DBHLEIBD_00069 9.1e-68 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
DBHLEIBD_00070 1.3e-85 K response regulator
DBHLEIBD_00071 5.3e-86 phoR 2.7.13.3 T Histidine kinase
DBHLEIBD_00072 4.1e-08 KT PspC domain protein
DBHLEIBD_00073 3.5e-26 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
DBHLEIBD_00074 7.4e-132 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DBHLEIBD_00075 1.1e-112 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DBHLEIBD_00076 6.1e-273 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
DBHLEIBD_00077 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
DBHLEIBD_00078 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
DBHLEIBD_00079 1.1e-83 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
DBHLEIBD_00080 3.8e-79 ylbE GM NAD dependent epimerase dehydratase family protein
DBHLEIBD_00081 7.5e-126 rapZ S Displays ATPase and GTPase activities
DBHLEIBD_00082 6.3e-153 ybhK S Required for morphogenesis under gluconeogenic growth conditions
DBHLEIBD_00083 1.8e-149 whiA K May be required for sporulation
DBHLEIBD_00084 1.1e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DBHLEIBD_00086 2.7e-135 cggR K Putative sugar-binding domain
DBHLEIBD_00087 6.1e-180 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
DBHLEIBD_00088 1.1e-207 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
DBHLEIBD_00089 2.3e-128 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DBHLEIBD_00090 9.5e-234 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DBHLEIBD_00091 1.4e-131 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DBHLEIBD_00092 7.2e-103 K response regulator
DBHLEIBD_00093 1.8e-169 T PhoQ Sensor
DBHLEIBD_00094 1.1e-145 lmrP E Major Facilitator Superfamily
DBHLEIBD_00095 1e-178 clcA P chloride
DBHLEIBD_00096 2.8e-19 secG U Preprotein translocase
DBHLEIBD_00097 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
DBHLEIBD_00098 6.9e-70 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
DBHLEIBD_00099 3.1e-42 yxjI
DBHLEIBD_00100 2.4e-116 ycsE S Sucrose-6F-phosphate phosphohydrolase
DBHLEIBD_00101 8.9e-106 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DBHLEIBD_00102 2e-143 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
DBHLEIBD_00103 4.2e-56 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
DBHLEIBD_00104 3e-69 dnaQ 2.7.7.7 L DNA polymerase III
DBHLEIBD_00105 6e-115 murB 1.3.1.98 M Cell wall formation
DBHLEIBD_00106 2.4e-71 S Protein of unknown function (DUF1361)
DBHLEIBD_00107 8.5e-127 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DBHLEIBD_00108 5.3e-68 ybbR S YbbR-like protein
DBHLEIBD_00109 2.6e-226 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DBHLEIBD_00110 5.8e-29 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
DBHLEIBD_00111 4.9e-129 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
DBHLEIBD_00112 2.3e-19 cutC P Participates in the control of copper homeostasis
DBHLEIBD_00114 2.9e-94 S Bacterial membrane protein, YfhO
DBHLEIBD_00115 4.8e-198 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DBHLEIBD_00116 1.7e-163 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
DBHLEIBD_00117 4.9e-61 ybaK J Aminoacyl-tRNA editing domain
DBHLEIBD_00118 2.2e-98 rrmA 2.1.1.187 H Methyltransferase
DBHLEIBD_00119 4.4e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
DBHLEIBD_00120 6.8e-288 ftsK D Belongs to the FtsK SpoIIIE SftA family
DBHLEIBD_00121 2e-108 ymfF S Peptidase M16 inactive domain protein
DBHLEIBD_00122 9.3e-149 ymfH S Peptidase M16
DBHLEIBD_00123 4.9e-91 IQ Enoyl-(Acyl carrier protein) reductase
DBHLEIBD_00124 8.5e-64 ymfM S Helix-turn-helix domain
DBHLEIBD_00125 8e-84 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DBHLEIBD_00126 2.3e-159 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DBHLEIBD_00127 7.6e-182 rny S Endoribonuclease that initiates mRNA decay
DBHLEIBD_00128 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DBHLEIBD_00129 2.2e-226 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DBHLEIBD_00130 1.6e-71 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
DBHLEIBD_00131 8.2e-153 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
DBHLEIBD_00132 7.9e-183 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DBHLEIBD_00133 7.8e-208 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
DBHLEIBD_00134 1.4e-12 yajC U Preprotein translocase
DBHLEIBD_00136 4.3e-61 uspA T universal stress protein
DBHLEIBD_00138 2e-208 yfnA E Amino Acid
DBHLEIBD_00139 6.9e-117 lutA C Cysteine-rich domain
DBHLEIBD_00140 1.1e-244 lutB C 4Fe-4S dicluster domain
DBHLEIBD_00141 1.6e-65 yrjD S LUD domain
DBHLEIBD_00142 3.9e-146 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DBHLEIBD_00143 7.5e-13
DBHLEIBD_00144 1.2e-121 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
DBHLEIBD_00145 6.7e-187 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
DBHLEIBD_00146 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DBHLEIBD_00147 2.1e-36 yrzL S Belongs to the UPF0297 family
DBHLEIBD_00148 2.3e-59 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DBHLEIBD_00149 1.9e-33 yrzB S Belongs to the UPF0473 family
DBHLEIBD_00150 1.4e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
DBHLEIBD_00151 1.6e-17 cvpA S Colicin V production protein
DBHLEIBD_00152 7.2e-309 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
DBHLEIBD_00153 9.9e-41 trxA O Belongs to the thioredoxin family
DBHLEIBD_00154 1.1e-60 yslB S Protein of unknown function (DUF2507)
DBHLEIBD_00155 5.5e-72 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DBHLEIBD_00156 4.4e-41 S Phosphoesterase
DBHLEIBD_00159 1.3e-139 hprA 1.1.1.29 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DBHLEIBD_00160 2.8e-305 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
DBHLEIBD_00161 2.2e-214 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DBHLEIBD_00162 8.1e-199 oatA I Acyltransferase
DBHLEIBD_00163 1.4e-16
DBHLEIBD_00165 8.3e-139 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
DBHLEIBD_00166 1.7e-100 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
DBHLEIBD_00167 9.9e-218 recJ L Single-stranded-DNA-specific exonuclease RecJ
DBHLEIBD_00168 9.6e-81 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DBHLEIBD_00169 8.4e-298 S membrane
DBHLEIBD_00170 8.9e-279 pbp2b 3.4.16.4 M Penicillin-binding Protein
DBHLEIBD_00172 1.8e-45 yviA S Protein of unknown function (DUF421)
DBHLEIBD_00175 5e-124 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
DBHLEIBD_00176 5e-199 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
DBHLEIBD_00177 1.2e-52 tag 3.2.2.20 L glycosylase
DBHLEIBD_00178 3.2e-73 usp6 T universal stress protein
DBHLEIBD_00180 5.8e-188 rarA L recombination factor protein RarA
DBHLEIBD_00181 5.9e-24 yueI S Protein of unknown function (DUF1694)
DBHLEIBD_00182 7.5e-101 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DBHLEIBD_00183 1.6e-55 ytsP 1.8.4.14 T GAF domain-containing protein
DBHLEIBD_00184 1.2e-172 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DBHLEIBD_00185 2.2e-162 iscS2 2.8.1.7 E Aminotransferase class V
DBHLEIBD_00186 4.7e-195 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DBHLEIBD_00187 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
DBHLEIBD_00188 8.1e-137 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
DBHLEIBD_00189 6.2e-80 radC L DNA repair protein
DBHLEIBD_00190 4.5e-21 K Cold shock
DBHLEIBD_00191 3.6e-156 mreB D cell shape determining protein MreB
DBHLEIBD_00192 2.1e-88 mreC M Involved in formation and maintenance of cell shape
DBHLEIBD_00193 4.4e-54 mreD M rod shape-determining protein MreD
DBHLEIBD_00194 3.2e-76 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
DBHLEIBD_00195 3.1e-126 minD D Belongs to the ParA family
DBHLEIBD_00196 1.9e-94 glnP P ABC transporter permease
DBHLEIBD_00197 1.1e-89 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
DBHLEIBD_00198 1.4e-108 aatB ET ABC transporter substrate-binding protein
DBHLEIBD_00199 7.5e-100 D Alpha beta
DBHLEIBD_00201 2.7e-155 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
DBHLEIBD_00202 4.5e-08 S Protein of unknown function (DUF3397)
DBHLEIBD_00203 5.2e-64 mraZ K Belongs to the MraZ family
DBHLEIBD_00204 3.6e-142 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
DBHLEIBD_00205 2.5e-11 ftsL D cell division protein FtsL
DBHLEIBD_00206 6.9e-282 ftsI 3.4.16.4 M Penicillin-binding Protein
DBHLEIBD_00207 8.7e-136 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DBHLEIBD_00208 2.2e-185 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DBHLEIBD_00209 6.8e-153 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DBHLEIBD_00210 5.7e-62 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
DBHLEIBD_00211 5.2e-190 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
DBHLEIBD_00212 2.9e-179 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DBHLEIBD_00213 5e-33 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
DBHLEIBD_00214 3e-19 yggT S YGGT family
DBHLEIBD_00215 7.7e-82 ylmH S S4 domain protein
DBHLEIBD_00216 5.1e-62 divIVA D DivIVA domain protein
DBHLEIBD_00217 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DBHLEIBD_00218 4.4e-91 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
DBHLEIBD_00219 3.3e-74 draG O ADP-ribosylglycohydrolase
DBHLEIBD_00221 9.6e-85 2.7.7.12 C Domain of unknown function (DUF4931)
DBHLEIBD_00222 4.8e-93 T Calcineurin-like phosphoesterase superfamily domain
DBHLEIBD_00223 2.1e-48 lytE M LysM domain protein
DBHLEIBD_00224 2.3e-19 glpE P Rhodanese Homology Domain
DBHLEIBD_00225 5.7e-29 xlyB 3.5.1.28 CBM50 M LysM domain
DBHLEIBD_00226 2.6e-159 asnA 6.3.1.1 F aspartate--ammonia ligase
DBHLEIBD_00227 3e-193 cydA 1.10.3.14 C ubiquinol oxidase
DBHLEIBD_00228 5.6e-141 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
DBHLEIBD_00229 7.8e-204 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
DBHLEIBD_00230 3.6e-220 cydD CO ABC transporter transmembrane region
DBHLEIBD_00231 6.2e-97 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
DBHLEIBD_00232 3.3e-105 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
DBHLEIBD_00233 2.5e-156 ndh 1.6.99.3 C NADH dehydrogenase
DBHLEIBD_00234 3.7e-11 pbuO_1 S Permease family
DBHLEIBD_00235 1.8e-124 pbuO_1 S Permease family
DBHLEIBD_00236 8.1e-43 2.7.7.65 T GGDEF domain
DBHLEIBD_00237 1.7e-129 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
DBHLEIBD_00238 9.3e-182
DBHLEIBD_00239 2.6e-206 S Protein conserved in bacteria
DBHLEIBD_00240 7.7e-201 ydaM M Glycosyl transferase family group 2
DBHLEIBD_00241 0.0 ydaN S Bacterial cellulose synthase subunit
DBHLEIBD_00242 2.4e-113 2.7.7.65 T diguanylate cyclase activity
DBHLEIBD_00243 1.7e-38 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
DBHLEIBD_00244 1.9e-50 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
DBHLEIBD_00245 5.9e-308 L Helicase C-terminal domain protein
DBHLEIBD_00246 0.0 rafA 3.2.1.22 G alpha-galactosidase
DBHLEIBD_00247 8.9e-54 S Membrane
DBHLEIBD_00248 3.5e-64 K helix_turn_helix, arabinose operon control protein
DBHLEIBD_00249 2.3e-45
DBHLEIBD_00250 5e-204 pipD E Dipeptidase
DBHLEIBD_00251 1.1e-23 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
DBHLEIBD_00252 2.4e-189 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
DBHLEIBD_00253 3e-61 speG J Acetyltransferase (GNAT) domain
DBHLEIBD_00254 5.1e-113 yitU 3.1.3.104 S hydrolase
DBHLEIBD_00255 1.8e-83 yjfP S COG1073 Hydrolases of the alpha beta superfamily
DBHLEIBD_00256 4.8e-81
DBHLEIBD_00257 3.8e-177 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
DBHLEIBD_00258 6.7e-42 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
DBHLEIBD_00259 1.8e-48 cps4C M Chain length determinant protein
DBHLEIBD_00260 9.4e-65 cpsD D AAA domain
DBHLEIBD_00261 6e-89 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM CoA-binding domain
DBHLEIBD_00262 9.8e-127 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
DBHLEIBD_00263 3.8e-165 2.6.1.102 M Belongs to the DegT DnrJ EryC1 family
DBHLEIBD_00264 4.8e-77 epsL M Bacterial sugar transferase
DBHLEIBD_00265 2.2e-25 pglD 2.3.1.203 S Bacterial transferase hexapeptide (six repeats)
DBHLEIBD_00266 1.9e-123 2.4.1.52 GT4 M Glycosyl transferases group 1
DBHLEIBD_00267 8.1e-80 gtf1 2.4.1.52 GT4 M glycosyl transferase group 1
DBHLEIBD_00269 9.3e-60 gtf1 2.4.1.52 GT4 M glycosyl transferase group 1
DBHLEIBD_00270 1.3e-74 M Glycosyltransferase Family 4
DBHLEIBD_00271 1.7e-42 GT2 V Glycosyl transferase, family 2
DBHLEIBD_00272 2.5e-57 pglI 2.4.1.293 GT2 M Glycosyltransferase like family 2
DBHLEIBD_00274 1.6e-52
DBHLEIBD_00275 8.8e-116 S Glycosyltransferase WbsX
DBHLEIBD_00276 4.5e-61 cps1B GT2,GT4 M Glycosyl transferases group 1
DBHLEIBD_00277 6.9e-103 cps2I S Psort location CytoplasmicMembrane, score
DBHLEIBD_00278 6.1e-146 lspL 5.1.3.6 GM RmlD substrate binding domain
DBHLEIBD_00279 9.8e-180 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DBHLEIBD_00280 6.9e-65 M Glycosyl transferases group 1
DBHLEIBD_00281 5.6e-126 M Glycosyl transferases group 1
DBHLEIBD_00284 7.5e-83 qorB 1.6.5.2 GM NmrA-like family
DBHLEIBD_00285 3.6e-39 K Transcriptional regulator
DBHLEIBD_00286 5e-71 1.1.1.1 C Zinc-binding dehydrogenase
DBHLEIBD_00288 5.7e-41 S Protein of unknown function (DUF1211)
DBHLEIBD_00289 7.3e-27 ybl78 L Conserved phage C-terminus (Phg_2220_C)
DBHLEIBD_00291 6.9e-39 wecD M Acetyltransferase (GNAT) family
DBHLEIBD_00292 1.6e-65 H Methyltransferase domain
DBHLEIBD_00294 2.9e-16 K DNA-templated transcription, initiation
DBHLEIBD_00296 2.2e-08 S Protein of unknown function (DUF2922)
DBHLEIBD_00299 4.9e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
DBHLEIBD_00300 2.9e-27 ysxB J Cysteine protease Prp
DBHLEIBD_00301 1.6e-42 rpmA J Belongs to the bacterial ribosomal protein bL27 family
DBHLEIBD_00302 1e-12
DBHLEIBD_00305 3.1e-71
DBHLEIBD_00306 1.4e-101 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
DBHLEIBD_00307 2.5e-177 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
DBHLEIBD_00308 1e-122 xerC D Belongs to the 'phage' integrase family. XerC subfamily
DBHLEIBD_00309 7e-79 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DBHLEIBD_00310 7.8e-218 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DBHLEIBD_00311 2.3e-36 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DBHLEIBD_00312 1.2e-58 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DBHLEIBD_00313 1.1e-56 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DBHLEIBD_00314 6.4e-99 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
DBHLEIBD_00315 1.5e-58 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DBHLEIBD_00316 7e-51 yeaL S Protein of unknown function (DUF441)
DBHLEIBD_00317 9.6e-126 cvfB S S1 domain
DBHLEIBD_00318 9.6e-113 xerD D recombinase XerD
DBHLEIBD_00319 3.8e-294 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
DBHLEIBD_00320 1.8e-76 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
DBHLEIBD_00321 2.8e-188 nhaC C Na H antiporter NhaC
DBHLEIBD_00322 6e-65 ypsA S Belongs to the UPF0398 family
DBHLEIBD_00323 1.2e-196 ade 3.5.4.2 F Adenine deaminase C-terminal domain
DBHLEIBD_00325 6.3e-73 2.3.1.178 M GNAT acetyltransferase
DBHLEIBD_00326 6.7e-68 maa 2.3.1.79 S Maltose acetyltransferase
DBHLEIBD_00327 2.8e-56 3.6.1.27 I Acid phosphatase homologues
DBHLEIBD_00328 1.1e-80 XK27_07525 3.6.1.55 F Hydrolase, nudix family
DBHLEIBD_00330 2.2e-68 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DBHLEIBD_00331 9.9e-110 pepE 3.4.13.21 E Alpha/beta hydrolase of unknown function (DUF915)
DBHLEIBD_00332 5.9e-38 K Transcriptional regulator
DBHLEIBD_00333 5.9e-53 EGP Major Facilitator Superfamily
DBHLEIBD_00334 3.1e-167 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
DBHLEIBD_00335 3.3e-281 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
DBHLEIBD_00336 7.6e-213 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
DBHLEIBD_00337 2.8e-186 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
DBHLEIBD_00339 4.3e-88 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DBHLEIBD_00340 2.2e-44
DBHLEIBD_00341 8.4e-121 ica2 GT2 M Glycosyl transferase family group 2
DBHLEIBD_00342 7.9e-45 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
DBHLEIBD_00343 6.4e-221 mntH P H( )-stimulated, divalent metal cation uptake system
DBHLEIBD_00344 7.6e-61 ypbB 5.1.3.1 S Helix-turn-helix domain
DBHLEIBD_00345 2e-128 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
DBHLEIBD_00346 7.7e-12 M Lysin motif
DBHLEIBD_00347 4.9e-85 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
DBHLEIBD_00348 4.4e-83 lytH 3.5.1.28 M Ami_3
DBHLEIBD_00349 5.4e-154 phoH T phosphate starvation-inducible protein PhoH
DBHLEIBD_00350 1.9e-59 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DBHLEIBD_00351 3.6e-30 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
DBHLEIBD_00352 1.3e-154 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DBHLEIBD_00353 6.9e-91 recO L Involved in DNA repair and RecF pathway recombination
DBHLEIBD_00354 2.6e-07 dltX S D-Ala-teichoic acid biosynthesis protein
DBHLEIBD_00355 3.4e-219 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DBHLEIBD_00356 2e-174 dltB M MBOAT, membrane-bound O-acyltransferase family
DBHLEIBD_00357 4.9e-29 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DBHLEIBD_00358 1.5e-151 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DBHLEIBD_00359 5.3e-58 arsC 1.20.4.1 T Low molecular weight phosphatase family
DBHLEIBD_00360 2.7e-171 rpsA 1.17.7.4 J Ribosomal protein S1
DBHLEIBD_00361 5.9e-228 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
DBHLEIBD_00362 8.5e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
DBHLEIBD_00364 1.8e-22 K Acetyltransferase (GNAT) domain
DBHLEIBD_00365 3.7e-112 natA S Domain of unknown function (DUF4162)
DBHLEIBD_00366 6.5e-80 natB CP ABC-type Na efflux pump, permease component
DBHLEIBD_00367 7e-95 EG EamA-like transporter family
DBHLEIBD_00368 4.5e-80 yjjH S Calcineurin-like phosphoesterase
DBHLEIBD_00369 1.3e-187 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DBHLEIBD_00370 2.4e-40 6.3.3.2 S ASCH
DBHLEIBD_00371 2.5e-69 lepB 3.4.21.89 U Signal peptidase, peptidase S26
DBHLEIBD_00372 8.2e-117 degV S EDD domain protein, DegV family
DBHLEIBD_00373 8.9e-40 K Transcriptional regulator
DBHLEIBD_00374 2.7e-201 FbpA K Fibronectin-binding protein
DBHLEIBD_00375 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DBHLEIBD_00376 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DBHLEIBD_00377 4.2e-83 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
DBHLEIBD_00378 1e-39 ypaA S Protein of unknown function (DUF1304)
DBHLEIBD_00380 6.3e-310 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
DBHLEIBD_00381 1.5e-167 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
DBHLEIBD_00382 0.0 dnaE 2.7.7.7 L DNA polymerase
DBHLEIBD_00383 4.3e-15 S Protein of unknown function (DUF2929)
DBHLEIBD_00384 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
DBHLEIBD_00385 4.3e-203 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
DBHLEIBD_00386 1.4e-40 XK27_04120 S Putative amino acid metabolism
DBHLEIBD_00387 4.6e-160 iscS 2.8.1.7 E Aminotransferase class V
DBHLEIBD_00388 4.6e-91 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DBHLEIBD_00390 2.6e-81 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
DBHLEIBD_00391 1.8e-128 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DBHLEIBD_00392 2.5e-160 nhaC C Na H antiporter NhaC
DBHLEIBD_00393 7e-127 corA P CorA-like Mg2+ transporter protein
DBHLEIBD_00394 1.5e-298 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
DBHLEIBD_00395 6.9e-205 hisS 6.1.1.21 J histidyl-tRNA synthetase
DBHLEIBD_00396 2.8e-150 S Tetratricopeptide repeat protein
DBHLEIBD_00397 4.9e-136 EG EamA-like transporter family
DBHLEIBD_00398 2.5e-70 alkD L DNA alkylation repair enzyme
DBHLEIBD_00399 6.5e-184 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
DBHLEIBD_00400 1.3e-103 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DBHLEIBD_00401 1e-77 trmK 2.1.1.217 S SAM-dependent methyltransferase
DBHLEIBD_00402 4.3e-149 EGP Sugar (and other) transporter
DBHLEIBD_00405 6.1e-39
DBHLEIBD_00406 5.9e-257 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
DBHLEIBD_00407 3.3e-22 S Family of unknown function (DUF5322)
DBHLEIBD_00408 1.4e-36 rnhA 3.1.26.4 L Ribonuclease HI
DBHLEIBD_00409 2.7e-173 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
DBHLEIBD_00410 1.1e-35 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
DBHLEIBD_00412 2.4e-88 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
DBHLEIBD_00413 1.8e-172 patA 2.6.1.1 E Aminotransferase
DBHLEIBD_00414 8.6e-115 glcR K DeoR C terminal sensor domain
DBHLEIBD_00415 8.3e-144 ppaC 3.6.1.1 C inorganic pyrophosphatase
DBHLEIBD_00416 1.6e-134 K Transcriptional regulator
DBHLEIBD_00417 9.7e-88 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DBHLEIBD_00418 1.8e-85 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
DBHLEIBD_00419 2.1e-189 carB 6.3.5.5 F Carbamoyl-phosphate synthase
DBHLEIBD_00420 2.2e-114 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
DBHLEIBD_00421 3.5e-204 pyrP F Permease
DBHLEIBD_00422 1.3e-75 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DBHLEIBD_00423 3.6e-128 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
DBHLEIBD_00424 2.3e-43 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DBHLEIBD_00425 2.5e-56 3.1.3.18 J HAD-hyrolase-like
DBHLEIBD_00426 2.3e-54 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
DBHLEIBD_00427 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DBHLEIBD_00428 2.2e-78 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
DBHLEIBD_00429 1.5e-118 prmA J Ribosomal protein L11 methyltransferase
DBHLEIBD_00430 3.8e-42 XK27_03960 S Protein of unknown function (DUF3013)
DBHLEIBD_00431 1.5e-143 iunH2 3.2.2.1 F nucleoside hydrolase
DBHLEIBD_00432 6.4e-12
DBHLEIBD_00433 1.7e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DBHLEIBD_00434 1.8e-97 udk 2.7.1.48 F Cytidine monophosphokinase
DBHLEIBD_00435 1.2e-128 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DBHLEIBD_00436 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DBHLEIBD_00437 7.4e-173 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DBHLEIBD_00438 6.9e-43 yodB K Transcriptional regulator, HxlR family
DBHLEIBD_00439 3.6e-67 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
DBHLEIBD_00440 1.7e-86 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DBHLEIBD_00443 1.7e-15
DBHLEIBD_00445 1.2e-277 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
DBHLEIBD_00446 4.3e-41 S Repeat protein
DBHLEIBD_00447 8.1e-101 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
DBHLEIBD_00448 6.7e-72 csm6 S Psort location Cytoplasmic, score
DBHLEIBD_00449 1.1e-31 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DBHLEIBD_00450 1.9e-87 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DBHLEIBD_00451 5e-70 csm5 L RAMP superfamily
DBHLEIBD_00452 5.1e-61 csm4 L CRISPR-associated RAMP protein, Csm4 family
DBHLEIBD_00453 9.8e-70 csm3 L RAMP superfamily
DBHLEIBD_00454 6e-29 csm2 L Csm2 Type III-A
DBHLEIBD_00455 2.5e-205 csm1 S CRISPR-associated protein Csm1 family
DBHLEIBD_00456 6.5e-34 cas6 S Pfam:DUF2276
DBHLEIBD_00457 1.5e-205 G PTS system Galactitol-specific IIC component
DBHLEIBD_00458 5.6e-210 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DBHLEIBD_00459 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DBHLEIBD_00460 3.3e-86 dprA LU DNA protecting protein DprA
DBHLEIBD_00461 4.9e-97 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DBHLEIBD_00462 2.1e-133 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DBHLEIBD_00463 3.6e-24 yozE S Belongs to the UPF0346 family
DBHLEIBD_00464 1.2e-53 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
DBHLEIBD_00465 2.9e-80 ypmR E GDSL-like Lipase/Acylhydrolase
DBHLEIBD_00467 2.3e-112 S Aldo keto reductase
DBHLEIBD_00468 2.7e-34 K helix_turn_helix, mercury resistance
DBHLEIBD_00469 3.4e-131 yvgN C Aldo keto reductase
DBHLEIBD_00470 1.2e-56 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DBHLEIBD_00471 2.6e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DBHLEIBD_00472 5e-276 yfmR S ABC transporter, ATP-binding protein
DBHLEIBD_00473 3e-133 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
DBHLEIBD_00474 5.3e-107 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
DBHLEIBD_00475 1.3e-106 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
DBHLEIBD_00476 1.8e-68 xerD L Phage integrase, N-terminal SAM-like domain
DBHLEIBD_00478 1.8e-56 yqeY S YqeY-like protein
DBHLEIBD_00479 4.7e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
DBHLEIBD_00480 1.1e-115 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
DBHLEIBD_00483 6.8e-101 epsJ1 M Glycosyltransferase like family 2
DBHLEIBD_00484 8e-87 M Glycosyltransferase sugar-binding region containing DXD motif
DBHLEIBD_00485 4.4e-90 M transferase activity, transferring glycosyl groups
DBHLEIBD_00486 9.6e-126 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
DBHLEIBD_00487 2.2e-77 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DBHLEIBD_00488 2.2e-82 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DBHLEIBD_00489 8.5e-56 dnaD L DnaD domain protein
DBHLEIBD_00490 7.6e-236 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
DBHLEIBD_00491 5.8e-142 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
DBHLEIBD_00492 1.9e-33 ypmB S Protein conserved in bacteria
DBHLEIBD_00493 3.1e-226 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
DBHLEIBD_00494 4e-93 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
DBHLEIBD_00495 3.7e-118 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
DBHLEIBD_00496 1.9e-136 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
DBHLEIBD_00497 1.3e-113 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
DBHLEIBD_00498 3.5e-103 holA 2.7.7.7 L DNA polymerase III delta subunit
DBHLEIBD_00499 9.4e-157 comEC S Competence protein ComEC
DBHLEIBD_00500 2e-69 comEB 3.5.4.12 F ComE operon protein 2
DBHLEIBD_00501 1.2e-49 comEA L Competence protein ComEA
DBHLEIBD_00502 4.2e-266 argS 6.1.1.19 J Arginyl-tRNA synthetase
DBHLEIBD_00503 4e-58 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
DBHLEIBD_00504 2.9e-20
DBHLEIBD_00506 3e-122 K LysR substrate binding domain
DBHLEIBD_00507 7.5e-195 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DBHLEIBD_00508 2.2e-108 S Acyltransferase family
DBHLEIBD_00509 6.4e-163 purD 6.3.4.13 F Belongs to the GARS family
DBHLEIBD_00510 1.4e-233 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
DBHLEIBD_00511 5.2e-75 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DBHLEIBD_00512 5.3e-139 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
DBHLEIBD_00513 2.1e-226 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DBHLEIBD_00514 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DBHLEIBD_00515 1.2e-102 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DBHLEIBD_00516 2.2e-30 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DBHLEIBD_00517 2.2e-96 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
DBHLEIBD_00518 2.4e-131 ylbL T Belongs to the peptidase S16 family
DBHLEIBD_00519 4e-49 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DBHLEIBD_00520 8e-73 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
DBHLEIBD_00521 1.1e-17 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
DBHLEIBD_00522 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DBHLEIBD_00523 2.3e-101 ftsW D Belongs to the SEDS family
DBHLEIBD_00524 3.6e-147 manN G system, mannose fructose sorbose family IID component
DBHLEIBD_00525 3.2e-115 manY G PTS system
DBHLEIBD_00526 1.6e-148 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
DBHLEIBD_00527 0.0 typA T GTP-binding protein TypA
DBHLEIBD_00528 2.2e-76 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
DBHLEIBD_00529 1.5e-24 yktA S Belongs to the UPF0223 family
DBHLEIBD_00530 4.1e-31 1.1.1.27 C L-malate dehydrogenase activity
DBHLEIBD_00531 6.3e-86 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DBHLEIBD_00532 5.5e-25
DBHLEIBD_00533 5e-23 ykzG S Belongs to the UPF0356 family
DBHLEIBD_00534 2.5e-300 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DBHLEIBD_00535 9.5e-248 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DBHLEIBD_00536 1e-197 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DBHLEIBD_00537 6e-196 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
DBHLEIBD_00538 8e-216 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DBHLEIBD_00539 1.6e-22 S Tetratricopeptide repeat
DBHLEIBD_00540 3.2e-266 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DBHLEIBD_00541 6.9e-116 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DBHLEIBD_00542 5.6e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DBHLEIBD_00543 1.8e-32 rpsT J Binds directly to 16S ribosomal RNA
DBHLEIBD_00544 3e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
DBHLEIBD_00545 3.7e-199 yfnA E amino acid
DBHLEIBD_00546 1.3e-40 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
DBHLEIBD_00547 1.9e-114 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
DBHLEIBD_00548 2.5e-57 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DBHLEIBD_00549 1.1e-26 ylqC S Belongs to the UPF0109 family
DBHLEIBD_00550 3.6e-42 rpsP J Belongs to the bacterial ribosomal protein bS16 family
DBHLEIBD_00551 5e-204 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DBHLEIBD_00552 1.2e-39 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DBHLEIBD_00553 1.4e-146 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DBHLEIBD_00554 1.1e-209 smc D Required for chromosome condensation and partitioning
DBHLEIBD_00555 3.9e-101 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
DBHLEIBD_00556 7e-26 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
DBHLEIBD_00557 1.8e-139 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
DBHLEIBD_00558 2.2e-245 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DBHLEIBD_00559 3.3e-239 yloV S DAK2 domain fusion protein YloV
DBHLEIBD_00560 4.5e-53 asp S Asp23 family, cell envelope-related function
DBHLEIBD_00561 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
DBHLEIBD_00562 3.5e-59 thiN 2.7.6.2 H thiamine pyrophosphokinase
DBHLEIBD_00563 8.4e-109 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
DBHLEIBD_00564 1.8e-192 KLT serine threonine protein kinase
DBHLEIBD_00565 1.9e-90 stp 3.1.3.16 T phosphatase
DBHLEIBD_00566 2e-154 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DBHLEIBD_00567 1.5e-140 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DBHLEIBD_00568 1.9e-288 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DBHLEIBD_00569 7.5e-121 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DBHLEIBD_00570 2.5e-21 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
DBHLEIBD_00571 1.1e-102 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
DBHLEIBD_00572 1.9e-94 2.7.1.89 M Phosphotransferase enzyme family
DBHLEIBD_00573 3.5e-26 arsC 1.20.4.1 P Belongs to the ArsC family
DBHLEIBD_00574 1e-186 rodA D Belongs to the SEDS family
DBHLEIBD_00575 1.3e-13 S Protein of unknown function (DUF2969)
DBHLEIBD_00576 9e-27 yidD S Could be involved in insertion of integral membrane proteins into the membrane
DBHLEIBD_00577 1.3e-166 mbl D Cell shape determining protein MreB Mrl
DBHLEIBD_00578 1.8e-195 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DBHLEIBD_00579 4.1e-15 ywzB S Protein of unknown function (DUF1146)
DBHLEIBD_00580 3e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
DBHLEIBD_00581 1.7e-236 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DBHLEIBD_00582 1.3e-141 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DBHLEIBD_00583 6.3e-266 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DBHLEIBD_00584 7e-58 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DBHLEIBD_00585 2.4e-39 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DBHLEIBD_00586 1.8e-15 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DBHLEIBD_00587 2.6e-97 atpB C it plays a direct role in the translocation of protons across the membrane
DBHLEIBD_00588 5e-100 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DBHLEIBD_00589 7.7e-135 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
DBHLEIBD_00590 1.4e-89 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
DBHLEIBD_00591 1.3e-177 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DBHLEIBD_00592 6.8e-86 tdk 2.7.1.21 F thymidine kinase
DBHLEIBD_00593 3e-219 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
DBHLEIBD_00594 3.5e-110 cobQ S glutamine amidotransferase
DBHLEIBD_00595 2e-111 ampC V Beta-lactamase
DBHLEIBD_00596 1.5e-31
DBHLEIBD_00597 2.6e-119 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
DBHLEIBD_00598 4.6e-205 glnP P ABC transporter
DBHLEIBD_00600 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
DBHLEIBD_00601 1.2e-160 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
DBHLEIBD_00602 1.5e-274 dnaK O Heat shock 70 kDa protein
DBHLEIBD_00603 4.2e-56 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DBHLEIBD_00604 1.4e-131 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
DBHLEIBD_00605 1.1e-95 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
DBHLEIBD_00606 3.1e-119 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DBHLEIBD_00607 1.3e-55 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DBHLEIBD_00608 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DBHLEIBD_00609 3.4e-25 ylxQ J ribosomal protein
DBHLEIBD_00610 1.2e-38 ylxR K Protein of unknown function (DUF448)
DBHLEIBD_00611 3.7e-170 nusA K Participates in both transcription termination and antitermination
DBHLEIBD_00612 2.7e-66 rimP J Required for maturation of 30S ribosomal subunits
DBHLEIBD_00613 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DBHLEIBD_00614 1e-259 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
DBHLEIBD_00615 2e-156 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
DBHLEIBD_00616 5.1e-102 cdsA 2.7.7.41 S Belongs to the CDS family
DBHLEIBD_00617 1.7e-105 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DBHLEIBD_00618 2.5e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
DBHLEIBD_00619 8.3e-115 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
DBHLEIBD_00620 2.7e-48 S Domain of unknown function (DUF956)
DBHLEIBD_00621 4.4e-37 ogt 2.1.1.63 H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DBHLEIBD_00623 2e-247 glnA 6.3.1.2 E glutamine synthetase
DBHLEIBD_00624 1.3e-45 glnR K Transcriptional regulator
DBHLEIBD_00625 3.6e-206 ynbB 4.4.1.1 P aluminum resistance
DBHLEIBD_00626 3.9e-109 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DBHLEIBD_00627 9.7e-17 WQ51_02665 S Protein of unknown function (DUF3042)
DBHLEIBD_00628 2.7e-46 yqhL P Rhodanese-like protein
DBHLEIBD_00629 6.2e-158 glk 2.7.1.2 G Glucokinase
DBHLEIBD_00630 1.5e-25 yqgQ S Bacterial protein of unknown function (DUF910)
DBHLEIBD_00631 2.4e-68 gluP 3.4.21.105 S Peptidase, S54 family
DBHLEIBD_00632 1.6e-38 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DBHLEIBD_00633 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
DBHLEIBD_00634 1.3e-19 D nuclear chromosome segregation
DBHLEIBD_00635 2.5e-75 yciQ P membrane protein (DUF2207)
DBHLEIBD_00636 2.1e-43 MA20_27270 S mazG nucleotide pyrophosphohydrolase
DBHLEIBD_00637 1.6e-92 engB D Necessary for normal cell division and for the maintenance of normal septation
DBHLEIBD_00638 2.9e-26 yneF S UPF0154 protein
DBHLEIBD_00639 2.2e-30 ynzC S UPF0291 protein
DBHLEIBD_00640 2.5e-83 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DBHLEIBD_00641 8.7e-176 recN L May be involved in recombinational repair of damaged DNA
DBHLEIBD_00642 6.6e-49 argR K Regulates arginine biosynthesis genes
DBHLEIBD_00643 1.2e-120 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
DBHLEIBD_00644 1.6e-83 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
DBHLEIBD_00645 9.6e-17 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DBHLEIBD_00646 9.9e-146 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DBHLEIBD_00647 2.3e-103 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DBHLEIBD_00648 5.5e-36 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DBHLEIBD_00649 3.7e-46 yqhY S Asp23 family, cell envelope-related function
DBHLEIBD_00650 2.1e-94 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DBHLEIBD_00651 1.3e-41 dut S dUTPase
DBHLEIBD_00652 5.5e-117
DBHLEIBD_00653 7.3e-105
DBHLEIBD_00654 4.7e-136 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
DBHLEIBD_00655 1.6e-23 acyP 3.6.1.7 C Belongs to the acylphosphatase family
DBHLEIBD_00656 5.1e-117 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DBHLEIBD_00657 6.6e-167 arlS 2.7.13.3 T Histidine kinase
DBHLEIBD_00658 3.1e-111 K response regulator
DBHLEIBD_00660 6.6e-107 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
DBHLEIBD_00661 3.5e-225 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DBHLEIBD_00662 7.1e-158 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DBHLEIBD_00663 1.4e-57 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DBHLEIBD_00664 3.4e-92 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
DBHLEIBD_00665 6.9e-37
DBHLEIBD_00666 1.4e-127 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DBHLEIBD_00667 1.9e-128 rpsB J Belongs to the universal ribosomal protein uS2 family
DBHLEIBD_00668 1.5e-27 yazA L GIY-YIG catalytic domain protein
DBHLEIBD_00669 8.5e-94 yabB 2.1.1.223 L Methyltransferase small domain
DBHLEIBD_00670 4e-89 plsC 2.3.1.51 I Acyltransferase
DBHLEIBD_00671 1.9e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
DBHLEIBD_00672 2e-57 yceD S Uncharacterized ACR, COG1399
DBHLEIBD_00673 2.5e-121 ylbM S Belongs to the UPF0348 family
DBHLEIBD_00674 1.5e-82 H Nodulation protein S (NodS)
DBHLEIBD_00675 1.5e-48 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
DBHLEIBD_00676 2.6e-69 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
DBHLEIBD_00677 3.5e-77 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DBHLEIBD_00678 6e-30 yhbY J RNA-binding protein
DBHLEIBD_00679 6.7e-180 yqeH S Ribosome biogenesis GTPase YqeH
DBHLEIBD_00680 1.2e-70 yqeG S HAD phosphatase, family IIIA
DBHLEIBD_00681 2.2e-52 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DBHLEIBD_00682 1.4e-24 rpmI J Belongs to the bacterial ribosomal protein bL35 family
DBHLEIBD_00683 1.3e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DBHLEIBD_00684 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DBHLEIBD_00685 1.3e-107 dnaI L Primosomal protein DnaI
DBHLEIBD_00686 3.6e-79 dnaB L replication initiation and membrane attachment
DBHLEIBD_00687 6.1e-66 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DBHLEIBD_00688 1.6e-50 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DBHLEIBD_00689 4.3e-107 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
DBHLEIBD_00690 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DBHLEIBD_00691 6.7e-69 ybhL S Belongs to the BI1 family
DBHLEIBD_00692 2.5e-61 phaJ I N-terminal half of MaoC dehydratase
DBHLEIBD_00693 7.6e-223 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
DBHLEIBD_00694 1.2e-239 sftA D Belongs to the FtsK SpoIIIE SftA family
DBHLEIBD_00695 4e-76 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DBHLEIBD_00696 4e-45 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
DBHLEIBD_00698 3.9e-100 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
DBHLEIBD_00699 1.6e-98 ytmP 2.7.1.89 M Choline/ethanolamine kinase
DBHLEIBD_00700 6.4e-72 ecsB U ABC transporter
DBHLEIBD_00701 1.3e-94 ecsA V ABC transporter, ATP-binding protein
DBHLEIBD_00702 2.7e-52 hit FG histidine triad
DBHLEIBD_00704 3.3e-113 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
DBHLEIBD_00705 8.6e-128 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
DBHLEIBD_00706 2e-21 yheA S Belongs to the UPF0342 family
DBHLEIBD_00707 3e-285 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
DBHLEIBD_00709 1.5e-86 ykuT M mechanosensitive ion channel
DBHLEIBD_00710 5.4e-177 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
DBHLEIBD_00711 3.9e-61 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
DBHLEIBD_00712 5.8e-45 ykuL S CBS domain
DBHLEIBD_00713 5.7e-119 gla U Major intrinsic protein
DBHLEIBD_00714 1.8e-301 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
DBHLEIBD_00715 3.1e-240 pgi 5.3.1.9 G Belongs to the GPI family
DBHLEIBD_00716 5.1e-231 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DBHLEIBD_00717 5.5e-109 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
DBHLEIBD_00718 4.4e-101 accA 2.1.3.15, 6.4.1.2 I alpha subunit
DBHLEIBD_00719 2.7e-125 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DBHLEIBD_00720 9.3e-216 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
DBHLEIBD_00721 3.9e-64 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
DBHLEIBD_00722 4.6e-47 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
DBHLEIBD_00723 2.1e-195 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
DBHLEIBD_00724 1.1e-98 IQ reductase
DBHLEIBD_00725 2.9e-104 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
DBHLEIBD_00726 2.2e-27 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
DBHLEIBD_00727 2.9e-102 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DBHLEIBD_00728 4.2e-61 marR K Transcriptional regulator, MarR family
DBHLEIBD_00729 3.4e-66 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
DBHLEIBD_00730 5.2e-36
DBHLEIBD_00732 3e-193 pepV 3.5.1.18 E dipeptidase PepV
DBHLEIBD_00733 1.2e-80 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DBHLEIBD_00734 4e-61 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
DBHLEIBD_00735 6.4e-187 ytgP S Polysaccharide biosynthesis protein
DBHLEIBD_00736 2.4e-192 cycA E Amino acid permease
DBHLEIBD_00737 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
DBHLEIBD_00738 7.4e-177 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DBHLEIBD_00741 4.8e-190 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DBHLEIBD_00742 5.5e-243 lysP E amino acid
DBHLEIBD_00743 6.8e-69 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
DBHLEIBD_00744 7.3e-271 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
DBHLEIBD_00745 3.2e-14 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DBHLEIBD_00746 9.4e-57 lssY 3.6.1.27 I phosphatidate phosphatase activity
DBHLEIBD_00747 4.5e-83 lysR5 K LysR substrate binding domain
DBHLEIBD_00748 1.7e-119 yxaA S membrane transporter protein
DBHLEIBD_00749 2.6e-32 ywjH S Protein of unknown function (DUF1634)
DBHLEIBD_00750 4.3e-123 brpA K Cell envelope-like function transcriptional attenuator common domain protein
DBHLEIBD_00751 1.7e-225 pipD E Dipeptidase
DBHLEIBD_00752 7.5e-20 K helix_turn_helix multiple antibiotic resistance protein
DBHLEIBD_00753 1.3e-164 EGP Major facilitator Superfamily
DBHLEIBD_00754 5.6e-82 S L,D-transpeptidase catalytic domain
DBHLEIBD_00755 7.8e-141 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
DBHLEIBD_00756 1.5e-144 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DBHLEIBD_00757 7.2e-27 ydiI Q Thioesterase superfamily
DBHLEIBD_00758 4.7e-56 yfeJ 6.3.5.2 F glutamine amidotransferase
DBHLEIBD_00759 9.6e-148 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
DBHLEIBD_00760 1.9e-113 degV S EDD domain protein, DegV family
DBHLEIBD_00761 3.7e-135 cadA P P-type ATPase
DBHLEIBD_00762 3.1e-88 cadA P P-type ATPase
DBHLEIBD_00763 1.8e-254 E Amino acid permease
DBHLEIBD_00764 6e-83 S Membrane
DBHLEIBD_00765 2e-49 cps3F
DBHLEIBD_00766 2.3e-300 fruA 2.7.1.202 GT Phosphotransferase System
DBHLEIBD_00767 4.5e-150 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
DBHLEIBD_00768 2.2e-86 fruR K DeoR C terminal sensor domain
DBHLEIBD_00769 3e-219 XK27_08635 S UPF0210 protein
DBHLEIBD_00770 4.1e-27 gcvR T Belongs to the UPF0237 family
DBHLEIBD_00771 6.1e-39
DBHLEIBD_00772 1.4e-76 E GDSL-like Lipase/Acylhydrolase family
DBHLEIBD_00773 9.2e-56 S Protein of unknown function (DUF975)
DBHLEIBD_00774 1.2e-148 lplA 6.3.1.20 H Lipoate-protein ligase
DBHLEIBD_00775 1.5e-229 lpdA 1.8.1.4 C Dehydrogenase
DBHLEIBD_00776 9e-181 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
DBHLEIBD_00777 5.7e-167 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
DBHLEIBD_00778 4.7e-178 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
DBHLEIBD_00779 1.3e-06 M MucBP domain
DBHLEIBD_00782 8.2e-219 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
DBHLEIBD_00783 1.2e-47 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
DBHLEIBD_00784 6.6e-69 coiA 3.6.4.12 S Competence protein
DBHLEIBD_00785 1.2e-229 pepF E oligoendopeptidase F
DBHLEIBD_00786 2.3e-41 yjbH Q Thioredoxin
DBHLEIBD_00787 1.9e-97 pstS P Phosphate
DBHLEIBD_00788 1.6e-118 pstC P probably responsible for the translocation of the substrate across the membrane
DBHLEIBD_00789 3.9e-122 pstA P Phosphate transport system permease protein PstA
DBHLEIBD_00790 2.7e-114 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DBHLEIBD_00791 4.7e-116 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DBHLEIBD_00792 3.6e-56 P Plays a role in the regulation of phosphate uptake
DBHLEIBD_00793 1.8e-148 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
DBHLEIBD_00794 1.1e-79 S VIT family
DBHLEIBD_00795 9.4e-84 S membrane
DBHLEIBD_00796 1.1e-39 M1-874 K Domain of unknown function (DUF1836)
DBHLEIBD_00797 1.8e-65 hly S protein, hemolysin III
DBHLEIBD_00798 7.1e-35 K helix_turn_helix, Arsenical Resistance Operon Repressor
DBHLEIBD_00799 1.3e-74 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DBHLEIBD_00802 5.1e-14
DBHLEIBD_00803 1.3e-172 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
DBHLEIBD_00804 1.3e-158 ccpA K catabolite control protein A
DBHLEIBD_00805 1.1e-41 S VanZ like family
DBHLEIBD_00806 1.5e-119 yebC K Transcriptional regulatory protein
DBHLEIBD_00807 2.3e-101 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DBHLEIBD_00808 1.1e-120 comGA NU Type II IV secretion system protein
DBHLEIBD_00809 3.4e-98 comGB NU type II secretion system
DBHLEIBD_00810 1.8e-26 comGC U competence protein ComGC
DBHLEIBD_00811 5e-14
DBHLEIBD_00813 1.6e-10 S Putative Competence protein ComGF
DBHLEIBD_00815 5.8e-98 ytxK 2.1.1.72 L N-6 DNA Methylase
DBHLEIBD_00816 1.7e-182 cycA E Amino acid permease
DBHLEIBD_00817 3e-57 S Calcineurin-like phosphoesterase
DBHLEIBD_00818 1.9e-53 yutD S Protein of unknown function (DUF1027)
DBHLEIBD_00819 2.9e-113 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
DBHLEIBD_00820 4.6e-32 S Protein of unknown function (DUF1461)
DBHLEIBD_00821 3e-92 dedA S SNARE associated Golgi protein
DBHLEIBD_00822 5.1e-94 trxB2 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
DBHLEIBD_00823 1.1e-49 yugI 5.3.1.9 J general stress protein
DBHLEIBD_00824 1.4e-260 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
DBHLEIBD_00825 2.1e-177 proV E ABC transporter, ATP-binding protein
DBHLEIBD_00826 1.3e-246 gshR 1.8.1.7 C Glutathione reductase
DBHLEIBD_00827 6.5e-102 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
DBHLEIBD_00828 9.4e-101
DBHLEIBD_00829 2.5e-38 S RelB antitoxin
DBHLEIBD_00830 4.8e-30
DBHLEIBD_00832 2e-09 S Domain of unknown function (DUF4176)
DBHLEIBD_00835 1.7e-96 norB EGP Major Facilitator
DBHLEIBD_00836 2.8e-102 tag 3.2.2.20 L Methyladenine glycosylase
DBHLEIBD_00837 6.7e-235 stp_1 EGP Major facilitator Superfamily
DBHLEIBD_00838 8.2e-72 H ThiF family
DBHLEIBD_00839 8.3e-207 arsR K DNA-binding transcription factor activity
DBHLEIBD_00840 8.9e-96 K Transcriptional regulator
DBHLEIBD_00841 2.5e-31 L Transposase
DBHLEIBD_00842 9.2e-50 L Transposase and inactivated derivatives IS30 family
DBHLEIBD_00843 1.2e-46 S Signal peptide protein, YSIRK family
DBHLEIBD_00844 5.1e-77 K response regulator
DBHLEIBD_00845 1.3e-89 saeS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
DBHLEIBD_00846 1.5e-23 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DBHLEIBD_00847 8e-111 L hmm pf00665
DBHLEIBD_00848 1.8e-96 pncA Q Isochorismatase family
DBHLEIBD_00849 6.2e-271 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DBHLEIBD_00850 3.1e-130 3.6.1.13, 3.6.1.55 F NUDIX domain
DBHLEIBD_00851 2.4e-98 M hydrolase, family 25
DBHLEIBD_00852 2.7e-21 S Bacteriophage holin of superfamily 6 (Holin_LLH)
DBHLEIBD_00859 1.5e-21
DBHLEIBD_00861 7.7e-122 rny D peptidase
DBHLEIBD_00862 6e-77 S Phage tail protein
DBHLEIBD_00863 2e-305 M Phage tail tape measure protein TP901
DBHLEIBD_00865 1.3e-16 S Phage tail assembly chaperone proteins, TAC
DBHLEIBD_00866 3.5e-78 S Phage tail tube protein
DBHLEIBD_00867 3e-55 S Protein of unknown function (DUF806)
DBHLEIBD_00868 1.4e-53 S Bacteriophage HK97-gp10, putative tail-component
DBHLEIBD_00869 5.1e-57 S Phage head-tail joining protein
DBHLEIBD_00870 2.4e-21 S Phage gp6-like head-tail connector protein
DBHLEIBD_00871 2.3e-194 S Phage capsid family
DBHLEIBD_00872 6.6e-112 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
DBHLEIBD_00873 1e-207 S Phage portal protein
DBHLEIBD_00875 0.0 S Phage Terminase
DBHLEIBD_00876 1.6e-79 L Phage terminase, small subunit
DBHLEIBD_00877 9.8e-84 L HNH nucleases
DBHLEIBD_00880 1.5e-28 S Predicted membrane protein (DUF2335)
DBHLEIBD_00882 8.8e-35 arpU S Phage transcriptional regulator, ArpU family
DBHLEIBD_00890 2.2e-70
DBHLEIBD_00891 1.6e-25
DBHLEIBD_00894 2.8e-28 S Phage replisome organizer, N-terminal domain protein
DBHLEIBD_00895 1.7e-54 S Putative HNHc nuclease
DBHLEIBD_00900 4.2e-45 S DNA binding
DBHLEIBD_00901 3.4e-29 XK27_07105 K Helix-turn-helix XRE-family like proteins
DBHLEIBD_00902 1e-22 K Cro/C1-type HTH DNA-binding domain
DBHLEIBD_00904 2e-16
DBHLEIBD_00907 2e-37 K Helix-turn-helix domain
DBHLEIBD_00908 2.3e-13 S Pfam:DUF955
DBHLEIBD_00911 2.6e-27 S Domain of unknown function (DUF4352)
DBHLEIBD_00912 2.2e-31
DBHLEIBD_00913 2.6e-24 S Domain of unknown function (DUF4393)
DBHLEIBD_00915 9.7e-23
DBHLEIBD_00916 1.9e-31 S ParE toxin of type II toxin-antitoxin system, parDE
DBHLEIBD_00917 6.6e-90 sip L Belongs to the 'phage' integrase family
DBHLEIBD_00918 6.2e-48 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
DBHLEIBD_00919 7.6e-55 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
DBHLEIBD_00920 4.9e-148 D CobQ CobB MinD ParA nucleotide binding domain protein
DBHLEIBD_00921 8.5e-35
DBHLEIBD_00922 1.9e-168 repA S Replication initiator protein A
DBHLEIBD_00923 3.5e-132 S Fic/DOC family
DBHLEIBD_00924 1.1e-39 relB L Addiction module antitoxin, RelB DinJ family
DBHLEIBD_00925 1.2e-25
DBHLEIBD_00926 9.2e-116 S protein conserved in bacteria
DBHLEIBD_00927 6.8e-41
DBHLEIBD_00928 5.5e-27
DBHLEIBD_00929 0.0 L MobA MobL family protein
DBHLEIBD_00930 1.5e-42 hxlR K Transcriptional regulator, HxlR family
DBHLEIBD_00931 1.1e-194 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
DBHLEIBD_00932 2.5e-93
DBHLEIBD_00933 1.6e-75 cylA V abc transporter atp-binding protein
DBHLEIBD_00934 9.1e-60 cylB V ABC-2 type transporter
DBHLEIBD_00935 7e-27 K COG3279 Response regulator of the LytR AlgR family
DBHLEIBD_00936 1.4e-10 S Protein of unknown function (DUF3021)
DBHLEIBD_00937 3.9e-156 L Transposase
DBHLEIBD_00938 1.9e-168 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
DBHLEIBD_00939 4.7e-210 glnP P ABC transporter
DBHLEIBD_00941 1.1e-59 uspA T Universal stress protein family
DBHLEIBD_00942 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
DBHLEIBD_00943 1.1e-25
DBHLEIBD_00944 1.4e-200 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
DBHLEIBD_00945 8e-110 puuD S peptidase C26
DBHLEIBD_00946 1.4e-83 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DBHLEIBD_00947 3.3e-150 lsa S ABC transporter
DBHLEIBD_00948 9.4e-149 mepA V MATE efflux family protein
DBHLEIBD_00949 2.2e-201 argH 4.3.2.1 E argininosuccinate lyase
DBHLEIBD_00950 1.7e-197 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
DBHLEIBD_00951 3.4e-150 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
DBHLEIBD_00952 9.9e-127 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DBHLEIBD_00953 4.7e-103 pfoS S Phosphotransferase system, EIIC
DBHLEIBD_00957 3.4e-149 cbiO2 P ABC transporter
DBHLEIBD_00958 3e-156 P ABC transporter
DBHLEIBD_00959 4.8e-132 cbiQ P Cobalt transport protein
DBHLEIBD_00960 2.2e-89 2.7.7.65 T phosphorelay sensor kinase activity
DBHLEIBD_00961 1.8e-106 L PLD-like domain
DBHLEIBD_00963 1.4e-09 tcdC
DBHLEIBD_00966 3.1e-233 tetP J elongation factor G
DBHLEIBD_00967 1.6e-31 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DBHLEIBD_00969 6.9e-217 yjeM E Amino Acid
DBHLEIBD_00970 1.5e-56 yphA GM NAD dependent epimerase/dehydratase family
DBHLEIBD_00971 4.3e-75 K Helix-turn-helix domain, rpiR family
DBHLEIBD_00972 2.5e-92 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
DBHLEIBD_00973 1.3e-127 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
DBHLEIBD_00974 6.5e-90 nanK GK ROK family
DBHLEIBD_00975 1.1e-53 ndk 2.7.4.6 F Belongs to the NDK family
DBHLEIBD_00976 4e-64 G Xylose isomerase domain protein TIM barrel
DBHLEIBD_00977 5.6e-153 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
DBHLEIBD_00978 7.8e-208 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DBHLEIBD_00979 1.1e-73 sdaAB 4.3.1.17 E Serine dehydratase beta chain
DBHLEIBD_00980 4.7e-112 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
DBHLEIBD_00981 7.7e-41 S Iron-sulfur cluster assembly protein
DBHLEIBD_00982 1.3e-66 S Protein of unknown function (DUF1440)
DBHLEIBD_00983 1.7e-81 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
DBHLEIBD_00984 5.9e-187 mtnE 2.6.1.83 E Aminotransferase
DBHLEIBD_00986 2.7e-15
DBHLEIBD_00987 1e-87 S Haloacid dehalogenase-like hydrolase
DBHLEIBD_00990 2.9e-71 xerD L Phage integrase, N-terminal SAM-like domain
DBHLEIBD_00991 6.3e-266 fbp 3.1.3.11 G phosphatase activity
DBHLEIBD_00993 9.2e-32 tonB M YSIRK type signal peptide
DBHLEIBD_00996 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
DBHLEIBD_00997 3e-98 fabK 1.3.1.9 S Nitronate monooxygenase
DBHLEIBD_00998 1.1e-21 S Phage minor capsid protein 2
DBHLEIBD_01003 4.3e-07
DBHLEIBD_01006 1.7e-52 M Phage tail tape measure protein TP901
DBHLEIBD_01007 1e-26 M by MetaGeneAnnotator
DBHLEIBD_01008 5.2e-110 IQ NAD dependent epimerase/dehydratase family
DBHLEIBD_01009 1.7e-103 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
DBHLEIBD_01010 4.5e-43 gutM K Glucitol operon activator protein (GutM)
DBHLEIBD_01011 4.8e-83 srlA G PTS system enzyme II sorbitol-specific factor
DBHLEIBD_01012 2.7e-135 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
DBHLEIBD_01013 2.4e-36 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
DBHLEIBD_01014 2.8e-64 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
DBHLEIBD_01015 4.2e-117 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
DBHLEIBD_01016 7.3e-136 pfoS S Phosphotransferase system, EIIC
DBHLEIBD_01017 1.6e-26 K Helix-turn-helix XRE-family like proteins
DBHLEIBD_01018 5.3e-24 S protein encoded in hypervariable junctions of pilus gene clusters
DBHLEIBD_01019 2.9e-224 E ABC transporter, substratebinding protein
DBHLEIBD_01020 4e-115 sufC O FeS assembly ATPase SufC
DBHLEIBD_01021 1.1e-143 sufD O FeS assembly protein SufD
DBHLEIBD_01022 1.1e-146 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DBHLEIBD_01023 4.9e-41 nifU C SUF system FeS assembly protein, NifU family
DBHLEIBD_01024 9.4e-240 sufB O assembly protein SufB
DBHLEIBD_01025 7.2e-45 S VIT family
DBHLEIBD_01026 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
DBHLEIBD_01027 1.5e-136 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DBHLEIBD_01028 4.7e-112 rssA S Phospholipase, patatin family
DBHLEIBD_01029 3.1e-15
DBHLEIBD_01031 2.8e-38
DBHLEIBD_01032 1.5e-57 S Region found in RelA / SpoT proteins
DBHLEIBD_01033 8.5e-70 S Protein of unknown function (DUF4065)
DBHLEIBD_01034 2.1e-87 S Fic/DOC family
DBHLEIBD_01035 2.2e-11 S sequence-specific DNA binding
DBHLEIBD_01036 1.7e-11 3.4.21.88 K Peptidase S24-like
DBHLEIBD_01041 1.4e-09 S Arc-like DNA binding domain
DBHLEIBD_01042 1.3e-20 S Replication initiator protein A (RepA) N-terminus
DBHLEIBD_01047 1.1e-08
DBHLEIBD_01052 7.5e-20
DBHLEIBD_01053 1.9e-11 polC 2.7.7.7 L BRCA1 C Terminus (BRCT) domain
DBHLEIBD_01057 2.4e-63 ruvB 3.6.4.12 L four-way junction helicase activity
DBHLEIBD_01059 5.1e-18 ps301 K PFAM helix-turn-helix domain protein
DBHLEIBD_01063 1.1e-77 S Fic/DOC family
DBHLEIBD_01064 6.2e-31 bcgIB 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
DBHLEIBD_01065 1.2e-185 bcgIB 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
DBHLEIBD_01067 5.2e-67 D nuclear chromosome segregation
DBHLEIBD_01068 7.5e-08
DBHLEIBD_01069 1.2e-61 gepA K Protein of unknown function (DUF4065)
DBHLEIBD_01070 1.6e-28
DBHLEIBD_01071 7e-56 Z012_06740 S Fic/DOC family
DBHLEIBD_01073 3.4e-09 XK27_00515 D Cell surface antigen C-terminus
DBHLEIBD_01074 2e-81 pac DM Glucan-binding protein C
DBHLEIBD_01075 3.4e-11 D Antitoxin component of a toxin-antitoxin (TA) module
DBHLEIBD_01076 3.5e-22 S PIN domain
DBHLEIBD_01077 3.2e-212 V N-6 DNA Methylase
DBHLEIBD_01078 6.6e-43 3.1.21.3 V type I restriction modification DNA specificity domain
DBHLEIBD_01080 1e-68
DBHLEIBD_01081 7.2e-44 L Protein of unknown function (DUF3991)
DBHLEIBD_01082 7.1e-165 topA2 5.99.1.2 G Topoisomerase IA
DBHLEIBD_01085 3.8e-140 clpB O Belongs to the ClpA ClpB family
DBHLEIBD_01089 8.4e-219 U TraM recognition site of TraD and TraG
DBHLEIBD_01090 3.4e-77
DBHLEIBD_01092 8.7e-26
DBHLEIBD_01093 4.5e-192 U type IV secretory pathway VirB4
DBHLEIBD_01095 4.1e-31 M CHAP domain
DBHLEIBD_01096 4.3e-19 NU amidase activity
DBHLEIBD_01099 6.5e-07
DBHLEIBD_01100 1.8e-42 sip L Belongs to the 'phage' integrase family
DBHLEIBD_01101 2.7e-30
DBHLEIBD_01102 1.7e-79 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
DBHLEIBD_01103 1.2e-99 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DBHLEIBD_01104 6.8e-79 yvfR V ABC transporter
DBHLEIBD_01105 2.7e-52 yvfS V ABC-2 type transporter
DBHLEIBD_01106 3.2e-57 salK 2.7.13.3 T Histidine kinase
DBHLEIBD_01107 2.4e-75 desR K helix_turn_helix, Lux Regulon
DBHLEIBD_01108 8.7e-39 ptp3 3.1.3.48 T Tyrosine phosphatase family
DBHLEIBD_01109 8.2e-13 ptp3 3.1.3.48 T Tyrosine phosphatase family
DBHLEIBD_01110 3.4e-103 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
DBHLEIBD_01115 1.4e-32 S Domain of unknown function (DUF4417)
DBHLEIBD_01116 1.1e-142 xerS L Phage integrase family
DBHLEIBD_01117 2e-71 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
DBHLEIBD_01118 6.5e-138 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DBHLEIBD_01119 1.6e-217 1.3.5.4 C FAD binding domain
DBHLEIBD_01120 5e-116 IQ Enoyl-(Acyl carrier protein) reductase
DBHLEIBD_01121 4.7e-138 G Xylose isomerase-like TIM barrel
DBHLEIBD_01122 3.7e-72 K Transcriptional regulator, LysR family
DBHLEIBD_01123 4.1e-98 EGP Major Facilitator Superfamily
DBHLEIBD_01124 2.6e-129 EGP Major Facilitator Superfamily
DBHLEIBD_01125 2.4e-35 L Integrase core domain
DBHLEIBD_01126 1.4e-41 L Integrase core domain
DBHLEIBD_01127 1.3e-20 L PFAM transposase IS3 IS911 family protein
DBHLEIBD_01128 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
DBHLEIBD_01129 1.7e-32 P Heavy-metal-associated domain
DBHLEIBD_01130 8.7e-31 tnp L Transposase IS66 family
DBHLEIBD_01131 5e-18 tnp
DBHLEIBD_01132 1.1e-42 L hmm pf00665
DBHLEIBD_01133 1.1e-124 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
DBHLEIBD_01134 4.6e-84 dps P Ferritin-like domain
DBHLEIBD_01135 1.1e-157 L transposase, IS605 OrfB family
DBHLEIBD_01136 2.5e-58 tlpA2 L Transposase IS200 like
DBHLEIBD_01137 4.1e-53 1.14.12.17 C Oxidoreductase NAD-binding domain
DBHLEIBD_01138 0.0 O Belongs to the peptidase S8 family
DBHLEIBD_01139 1e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
DBHLEIBD_01141 7.9e-44 yjaB_1 K Acetyltransferase (GNAT) domain
DBHLEIBD_01142 4.5e-80 yitS S EDD domain protein, DegV family
DBHLEIBD_01143 1.1e-57 racA K Domain of unknown function (DUF1836)
DBHLEIBD_01144 3.6e-116 queH 1.17.99.6, 3.1.26.4 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DBHLEIBD_01145 3.3e-147 ald 1.4.1.1 C Belongs to the AlaDH PNT family
DBHLEIBD_01146 7.3e-168 potE2 E amino acid
DBHLEIBD_01150 2.3e-07 S zinc-finger-containing domain
DBHLEIBD_01151 3.5e-157 spoVK O stage V sporulation protein K
DBHLEIBD_01154 5.5e-27
DBHLEIBD_01157 1.5e-14
DBHLEIBD_01158 1.5e-92 pstS P T5orf172
DBHLEIBD_01159 4.5e-256 yeeB L DEAD-like helicases superfamily
DBHLEIBD_01160 4.3e-222 yeeA V Type II restriction enzyme, methylase subunits
DBHLEIBD_01161 1.8e-14 yeeA V Type II restriction enzyme, methylase subunits
DBHLEIBD_01162 3.4e-59 yeeA V Type II restriction enzyme, methylase subunits
DBHLEIBD_01163 1.1e-64
DBHLEIBD_01164 4.4e-62
DBHLEIBD_01165 7.1e-161 L T/G mismatch-specific endonuclease activity
DBHLEIBD_01167 2.6e-56 hsdM 2.1.1.72 V type I restriction-modification system
DBHLEIBD_01168 1.1e-18 3.1.21.3 V Type I restriction modification DNA specificity domain
DBHLEIBD_01169 4e-106 L Belongs to the 'phage' integrase family
DBHLEIBD_01170 1.7e-19 S YjcQ protein
DBHLEIBD_01172 1.3e-108 rhaD 4.1.2.17, 4.1.2.19 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
DBHLEIBD_01173 2.2e-219 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
DBHLEIBD_01174 4e-40 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
DBHLEIBD_01175 3.7e-215 rhaB 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
DBHLEIBD_01176 1.5e-188 iolF EGP Major facilitator Superfamily
DBHLEIBD_01177 4.8e-76 rhaR K helix_turn_helix, arabinose operon control protein
DBHLEIBD_01178 4.2e-12 S Membrane
DBHLEIBD_01179 6.1e-181 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
DBHLEIBD_01180 1.5e-56 yvbG U MarC family integral membrane protein
DBHLEIBD_01181 4.2e-15 2.7.1.194, 2.7.1.202 GKT COG3711 Transcriptional antiterminator
DBHLEIBD_01182 1.2e-28 yedF O Belongs to the sulfur carrier protein TusA family
DBHLEIBD_01183 4.9e-149 yedE S Sulphur transport
DBHLEIBD_01184 7e-101 selD 2.7.9.3 E Synthesizes selenophosphate from selenide and ATP
DBHLEIBD_01185 2.4e-176 rnfC C RnfC Barrel sandwich hybrid domain
DBHLEIBD_01186 9e-29 yitW S Iron-sulfur cluster assembly protein
DBHLEIBD_01187 2.4e-110 selA 2.9.1.1 H Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis
DBHLEIBD_01188 1.1e-110 sufS 2.8.1.7, 4.4.1.16 E Serine hydroxymethyltransferase
DBHLEIBD_01189 1.4e-137 selB J Elongation factor SelB, winged helix
DBHLEIBD_01190 2.9e-07 S Protein of unknown function (DUF3343)
DBHLEIBD_01191 1.2e-48 yedF O Belongs to the sulfur carrier protein TusA family
DBHLEIBD_01192 7.7e-222 ybeC E amino acid
DBHLEIBD_01193 2.2e-93 XK27_00825 S Sulfite exporter TauE/SafE
DBHLEIBD_01194 1.7e-142 5.1.1.4 E Proline racemase
DBHLEIBD_01195 2.7e-66 3.5.1.1 EJ Glycine/sarcosine/betaine reductase component B subunits
DBHLEIBD_01196 8e-73 prdD S An automated process has identified a potential problem with this gene model
DBHLEIBD_01197 4.3e-31 S the current gene model (or a revised gene model) may contain a premature stop
DBHLEIBD_01198 4.5e-66 prdB 1.21.4.1, 1.21.4.2 S the current gene model (or a revised gene model) may contain a premature stop
DBHLEIBD_01199 7.1e-26 S Psort location Cytoplasmic, score
DBHLEIBD_01200 5.2e-233 prdA 1.21.4.1 EJ Glycine/sarcosine/betaine reductase component B subunits
DBHLEIBD_01202 5e-116 ynjE 2.8.1.11 P Rhodanese Homology Domain
DBHLEIBD_01203 5.4e-17 yeeD O Belongs to the sulfur carrier protein TusA family
DBHLEIBD_01204 3.1e-62 yeeE S Sulphur transport
DBHLEIBD_01205 8.8e-105 yraQ S Predicted permease
DBHLEIBD_01206 1.4e-124 yvgN C Aldo keto reductase
DBHLEIBD_01210 3.4e-16
DBHLEIBD_01213 5.8e-21 M domain protein
DBHLEIBD_01214 1.7e-30 agrA KT Response regulator of the LytR AlgR family
DBHLEIBD_01215 6.7e-43 blpH 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
DBHLEIBD_01216 0.0 pepN 3.4.11.2 E aminopeptidase
DBHLEIBD_01217 6.4e-36
DBHLEIBD_01219 7.6e-125 D CobQ CobB MinD ParA nucleotide binding domain protein
DBHLEIBD_01220 6e-17 bglG K antiterminator
DBHLEIBD_01221 7.1e-90 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
DBHLEIBD_01222 3.2e-171 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DBHLEIBD_01223 5.1e-38 S Replication initiator protein A (RepA) N-terminus
DBHLEIBD_01224 9.4e-109 L Initiator Replication protein
DBHLEIBD_01225 6.1e-08 yokH G regulation of fungal-type cell wall biogenesis
DBHLEIBD_01227 6.5e-12 L PLD-like domain
DBHLEIBD_01228 3.5e-23 L PLD-like domain
DBHLEIBD_01229 3.5e-182 L Probable transposase
DBHLEIBD_01230 4.6e-79
DBHLEIBD_01231 4.3e-258 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
DBHLEIBD_01232 5.7e-80 K SIR2-like domain
DBHLEIBD_01233 3.8e-22
DBHLEIBD_01234 8e-112 K IrrE N-terminal-like domain
DBHLEIBD_01235 4.1e-18
DBHLEIBD_01236 8.5e-64 V HNH endonuclease
DBHLEIBD_01240 2.1e-07
DBHLEIBD_01244 1.6e-75 xerC L Belongs to the 'phage' integrase family
DBHLEIBD_01245 3.6e-28 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
DBHLEIBD_01246 8.4e-38 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
DBHLEIBD_01247 2.5e-58 cpsF M Oligosaccharide biosynthesis protein Alg14 like
DBHLEIBD_01248 2e-91 rfbP M Bacterial sugar transferase
DBHLEIBD_01249 2.7e-144 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DBHLEIBD_01250 4.2e-101 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
DBHLEIBD_01251 1.6e-164 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
DBHLEIBD_01252 4e-129 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
DBHLEIBD_01254 6.2e-64 rny D Peptidase family M23
DBHLEIBD_01255 5.2e-43 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
DBHLEIBD_01256 6.9e-92 M Core-2/I-Branching enzyme
DBHLEIBD_01257 1.3e-76 waaB GT4 M Glycosyl transferases group 1
DBHLEIBD_01258 3.4e-93 M transferase activity, transferring glycosyl groups
DBHLEIBD_01259 1.1e-57 cps3F
DBHLEIBD_01260 2.4e-73 M LicD family
DBHLEIBD_01261 8.5e-64 M Glycosyltransferase like family 2
DBHLEIBD_01264 1e-43 S Peptidase_C39 like family
DBHLEIBD_01265 7.3e-38 S Acyltransferase family
DBHLEIBD_01266 1.2e-194 glf 5.4.99.9 M UDP-galactopyranose mutase
DBHLEIBD_01267 1.8e-153 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
DBHLEIBD_01269 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
DBHLEIBD_01270 7.3e-161 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
DBHLEIBD_01271 5.6e-97 dacA 3.4.16.4 M Belongs to the peptidase S11 family
DBHLEIBD_01272 1.9e-67 XK27_09620 S NADPH-dependent FMN reductase
DBHLEIBD_01273 7e-157 XK27_09615 S reductase
DBHLEIBD_01274 7.5e-39 2.7.7.65 T phosphorelay sensor kinase activity
DBHLEIBD_01275 1.8e-135 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
DBHLEIBD_01276 6.9e-77 S Psort location CytoplasmicMembrane, score
DBHLEIBD_01277 3.6e-14
DBHLEIBD_01278 3.5e-131 S Bacterial membrane protein YfhO
DBHLEIBD_01279 4.1e-177 thrC 4.2.3.1 E Threonine synthase
DBHLEIBD_01280 2.9e-126 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
DBHLEIBD_01281 1.2e-167 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
DBHLEIBD_01282 9.5e-89 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
DBHLEIBD_01283 2.2e-177 licA 2.7.1.89 M Choline/ethanolamine kinase
DBHLEIBD_01284 1.9e-84 M Nucleotidyl transferase
DBHLEIBD_01285 1.1e-150 M BCCT, betaine/carnitine/choline family transporter
DBHLEIBD_01286 5.9e-56 S peptidoglycan catabolic process
DBHLEIBD_01287 3.3e-21 XK27_08315 M Sulfatase
DBHLEIBD_01288 1.2e-167 XK27_08315 M Sulfatase
DBHLEIBD_01290 2.5e-167 mdtG EGP Major facilitator Superfamily
DBHLEIBD_01291 2.9e-251 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
DBHLEIBD_01292 5.7e-84 treR K UTRA
DBHLEIBD_01293 9.5e-259 treB G phosphotransferase system
DBHLEIBD_01294 4.6e-63 3.1.3.73 G phosphoglycerate mutase
DBHLEIBD_01295 7e-82 pncA Q isochorismatase
DBHLEIBD_01296 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
DBHLEIBD_01297 3.4e-103 ydhQ K UbiC transcription regulator-associated domain protein
DBHLEIBD_01298 1.7e-171 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
DBHLEIBD_01299 1.3e-41 K Transcriptional regulator, HxlR family
DBHLEIBD_01300 3.7e-164 C Luciferase-like monooxygenase
DBHLEIBD_01301 4.3e-66 1.5.1.38 S NADPH-dependent FMN reductase
DBHLEIBD_01302 4.4e-117 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
DBHLEIBD_01303 4.4e-75 L haloacid dehalogenase-like hydrolase
DBHLEIBD_01304 1.2e-60 EG EamA-like transporter family
DBHLEIBD_01305 4e-118 K AI-2E family transporter
DBHLEIBD_01306 1.2e-171 malY 4.4.1.8 E Aminotransferase, class I
DBHLEIBD_01307 6e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DBHLEIBD_01308 2.3e-59 yfjR K WYL domain
DBHLEIBD_01309 4e-11 S Mor transcription activator family
DBHLEIBD_01311 8.1e-09 S zinc-ribbon domain
DBHLEIBD_01316 9.2e-91 V domain protein
DBHLEIBD_01317 4.9e-119 xth 3.1.11.2 L exodeoxyribonuclease III
DBHLEIBD_01318 3.5e-17
DBHLEIBD_01319 1.9e-104 azlC E AzlC protein
DBHLEIBD_01320 1.3e-38 azlD S branched-chain amino acid
DBHLEIBD_01321 2.1e-66 I alpha/beta hydrolase fold
DBHLEIBD_01322 3.1e-25
DBHLEIBD_01323 2.1e-58 3.6.1.27 I phosphatase
DBHLEIBD_01324 3.1e-23
DBHLEIBD_01325 3.1e-95 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
DBHLEIBD_01326 8.3e-90 sirR K Helix-turn-helix diphteria tox regulatory element
DBHLEIBD_01327 3.1e-27 cspC K Cold shock protein
DBHLEIBD_01328 4.3e-82 thrE S Putative threonine/serine exporter
DBHLEIBD_01329 1.3e-49 S Threonine/Serine exporter, ThrE
DBHLEIBD_01330 3.7e-125 brpA K Cell envelope-like function transcriptional attenuator common domain protein
DBHLEIBD_01331 3.8e-87 S Sucrose-6F-phosphate phosphohydrolase
DBHLEIBD_01332 1.9e-34 trxA O Belongs to the thioredoxin family
DBHLEIBD_01333 2.7e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DBHLEIBD_01334 8.8e-22 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DBHLEIBD_01335 1.5e-65 degV S Uncharacterised protein, DegV family COG1307
DBHLEIBD_01337 4.3e-54 queT S QueT transporter
DBHLEIBD_01338 2.5e-33 XK27_01315 S Protein of unknown function (DUF2829)
DBHLEIBD_01339 1.4e-101 IQ Enoyl-(Acyl carrier protein) reductase
DBHLEIBD_01340 3e-111 argE 3.5.1.18 E Peptidase dimerisation domain
DBHLEIBD_01341 1.9e-174 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
DBHLEIBD_01342 4.6e-94 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
DBHLEIBD_01343 5e-87 S Alpha beta hydrolase
DBHLEIBD_01344 1.2e-43 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DBHLEIBD_01345 4.7e-140 V MatE
DBHLEIBD_01346 5.2e-156 gmuE 2.7.1.2, 2.7.1.4 GK ROK family
DBHLEIBD_01347 2e-64 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DBHLEIBD_01348 3.3e-97 V ABC transporter
DBHLEIBD_01349 1.6e-131 bacI V MacB-like periplasmic core domain
DBHLEIBD_01350 6.9e-74 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
DBHLEIBD_01351 3.7e-26
DBHLEIBD_01352 9.3e-181 yhdP S Transporter associated domain
DBHLEIBD_01353 6e-79 ptp2 3.1.3.48 T Tyrosine phosphatase family
DBHLEIBD_01354 0.0 L Helicase C-terminal domain protein
DBHLEIBD_01355 3.6e-250 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
DBHLEIBD_01356 6.3e-212 yfnA E Amino Acid
DBHLEIBD_01357 5.4e-53 zur P Belongs to the Fur family
DBHLEIBD_01358 3e-12 3.2.1.14 GH18
DBHLEIBD_01359 2.5e-97
DBHLEIBD_01360 1.3e-09
DBHLEIBD_01361 1.3e-102 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
DBHLEIBD_01362 1.9e-99 glnH ET ABC transporter
DBHLEIBD_01363 1.2e-85 gluC P ABC transporter permease
DBHLEIBD_01364 9.6e-78 glnP P ABC transporter permease
DBHLEIBD_01365 3.8e-182 steT E amino acid
DBHLEIBD_01366 6.5e-21 K Acetyltransferase (GNAT) domain
DBHLEIBD_01367 2.7e-145 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
DBHLEIBD_01368 2.6e-54 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
DBHLEIBD_01369 6.5e-79 K rpiR family
DBHLEIBD_01370 4.3e-167 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DBHLEIBD_01371 2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
DBHLEIBD_01372 4.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DBHLEIBD_01373 1e-100 rplD J Forms part of the polypeptide exit tunnel
DBHLEIBD_01374 2.9e-39 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
DBHLEIBD_01375 1.4e-142 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DBHLEIBD_01376 1e-44 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DBHLEIBD_01377 1.5e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DBHLEIBD_01378 5.2e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DBHLEIBD_01379 6.2e-73 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DBHLEIBD_01380 9e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
DBHLEIBD_01381 8e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DBHLEIBD_01382 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DBHLEIBD_01383 7e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DBHLEIBD_01384 1.3e-91 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DBHLEIBD_01385 4.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DBHLEIBD_01386 2.5e-65 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DBHLEIBD_01387 3.2e-87 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DBHLEIBD_01388 9.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DBHLEIBD_01389 1.3e-82 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DBHLEIBD_01390 2.1e-22 rpmD J Ribosomal protein L30
DBHLEIBD_01391 1e-67 rplO J Binds to the 23S rRNA
DBHLEIBD_01392 1.7e-206 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
DBHLEIBD_01393 4.4e-107 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
DBHLEIBD_01394 4.8e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DBHLEIBD_01395 2.5e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
DBHLEIBD_01396 4.4e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DBHLEIBD_01397 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DBHLEIBD_01398 1.7e-155 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DBHLEIBD_01399 4.8e-53 rplQ J Ribosomal protein L17
DBHLEIBD_01400 4e-100 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DBHLEIBD_01401 1.5e-110 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DBHLEIBD_01402 4.1e-107 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DBHLEIBD_01403 5.5e-125 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
DBHLEIBD_01404 5.5e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DBHLEIBD_01405 1.1e-60 rpsI J Belongs to the universal ribosomal protein uS9 family
DBHLEIBD_01406 1.4e-30
DBHLEIBD_01407 1.2e-245 yjbQ P TrkA C-terminal domain protein
DBHLEIBD_01408 0.0 helD 3.6.4.12 L DNA helicase
DBHLEIBD_01409 2.3e-87 devA 3.6.3.25 V ABC transporter, ATP-binding protein
DBHLEIBD_01410 9.6e-112 hrtB V ABC transporter permease
DBHLEIBD_01411 4.6e-35 ygfC K Bacterial regulatory proteins, tetR family
DBHLEIBD_01412 2.4e-85 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DBHLEIBD_01413 2.5e-277 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
DBHLEIBD_01414 4.6e-36 M LysM domain protein
DBHLEIBD_01415 3.4e-115 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
DBHLEIBD_01416 3.5e-101 sbcC L Putative exonuclease SbcCD, C subunit
DBHLEIBD_01417 9.9e-58 S LexA-binding, inner membrane-associated putative hydrolase
DBHLEIBD_01418 5.5e-53 perR P Belongs to the Fur family
DBHLEIBD_01419 2.9e-208 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DBHLEIBD_01420 1.4e-141 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DBHLEIBD_01421 2.5e-86 S (CBS) domain
DBHLEIBD_01422 3.6e-158 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
DBHLEIBD_01423 5.5e-74 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
DBHLEIBD_01424 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DBHLEIBD_01425 6.6e-141 yabM S Polysaccharide biosynthesis protein
DBHLEIBD_01426 3.6e-31 yabO J S4 domain protein
DBHLEIBD_01427 1e-21 divIC D Septum formation initiator
DBHLEIBD_01428 1.1e-40 yabR J RNA binding
DBHLEIBD_01429 3.6e-95 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
DBHLEIBD_01430 1.5e-76 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
DBHLEIBD_01431 2.3e-282 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DBHLEIBD_01433 2.5e-13
DBHLEIBD_01435 2.5e-132 S D5 N terminal like
DBHLEIBD_01436 8.2e-44 L DNA replication protein
DBHLEIBD_01446 2.5e-34 K Helix-turn-helix XRE-family like proteins
DBHLEIBD_01447 7.6e-09 E IrrE N-terminal-like domain
DBHLEIBD_01448 1.1e-69 sip L Belongs to the 'phage' integrase family
DBHLEIBD_01449 1.2e-29 sip L Belongs to the 'phage' integrase family
DBHLEIBD_01450 2e-131 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DBHLEIBD_01451 6.1e-169 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DBHLEIBD_01452 5.1e-260 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
DBHLEIBD_01453 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
DBHLEIBD_01454 6.8e-26 ykuJ S Protein of unknown function (DUF1797)
DBHLEIBD_01455 1.3e-129 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DBHLEIBD_01456 1.3e-126 cpoA GT4 M Glycosyltransferase, group 1 family protein
DBHLEIBD_01457 1.1e-161 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
DBHLEIBD_01458 2.4e-285 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DBHLEIBD_01459 9.7e-37 ptsH G phosphocarrier protein HPR
DBHLEIBD_01460 1.5e-15
DBHLEIBD_01461 0.0 clpE O Belongs to the ClpA ClpB family
DBHLEIBD_01462 1.9e-22 XK27_09445 S Domain of unknown function (DUF1827)
DBHLEIBD_01463 1.1e-104 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
DBHLEIBD_01464 0.0 rafA 3.2.1.22 G alpha-galactosidase
DBHLEIBD_01465 8.3e-202 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
DBHLEIBD_01466 1.6e-156 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
DBHLEIBD_01467 4.5e-179 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DBHLEIBD_01468 2.2e-110 galR K Transcriptional regulator
DBHLEIBD_01469 1.5e-58 lacS G Transporter
DBHLEIBD_01470 1.8e-206 lacS G Transporter
DBHLEIBD_01471 0.0 lacL 3.2.1.23 G -beta-galactosidase
DBHLEIBD_01472 7.5e-278 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DBHLEIBD_01473 1e-108 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
DBHLEIBD_01474 6.5e-158 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
DBHLEIBD_01475 6.9e-92 yueF S AI-2E family transporter
DBHLEIBD_01476 2.6e-97 ygaC J Belongs to the UPF0374 family
DBHLEIBD_01477 4.7e-191 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DBHLEIBD_01478 4.2e-67 recX 2.4.1.337 GT4 S Regulatory protein RecX
DBHLEIBD_01479 1.8e-19 sigH K DNA-templated transcription, initiation
DBHLEIBD_01480 7e-23 S Cytochrome B5
DBHLEIBD_01481 7.3e-47 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain (presumed)
DBHLEIBD_01482 4.4e-60
DBHLEIBD_01483 1.4e-42 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
DBHLEIBD_01484 6.6e-156 nrnB S DHHA1 domain
DBHLEIBD_01485 1.5e-91 yunF F Protein of unknown function DUF72
DBHLEIBD_01486 2e-48 ndoA L Toxic component of a toxin-antitoxin (TA) module
DBHLEIBD_01487 5.4e-13
DBHLEIBD_01488 8.2e-146 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DBHLEIBD_01489 1e-29 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
DBHLEIBD_01490 4.5e-208 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
DBHLEIBD_01491 5.3e-179 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
DBHLEIBD_01492 4.9e-65 S Uncharacterized protein conserved in bacteria (DUF2263)
DBHLEIBD_01493 3.5e-180 pbuG S permease
DBHLEIBD_01495 8e-79 S Cell surface protein
DBHLEIBD_01497 9.9e-258 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
DBHLEIBD_01498 2.8e-61
DBHLEIBD_01499 3.6e-41 rpmE2 J Ribosomal protein L31
DBHLEIBD_01500 3.1e-189 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DBHLEIBD_01501 4.6e-201 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DBHLEIBD_01504 5.2e-287 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
DBHLEIBD_01505 9.9e-42 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
DBHLEIBD_01506 9.1e-32 ywiB S Domain of unknown function (DUF1934)
DBHLEIBD_01507 3.4e-86 yfeJ 6.3.5.2 F glutamine amidotransferase
DBHLEIBD_01508 4.3e-205 ywfO S HD domain protein
DBHLEIBD_01509 4e-89 S hydrolase
DBHLEIBD_01510 6.5e-98 ydcZ S Putative inner membrane exporter, YdcZ
DBHLEIBD_01511 3.7e-22
DBHLEIBD_01512 1.7e-71
DBHLEIBD_01514 4.1e-39 L COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
DBHLEIBD_01516 4.3e-12
DBHLEIBD_01517 1.1e-55 spoVK O ATPase family associated with various cellular activities (AAA)
DBHLEIBD_01519 2.6e-87 S overlaps another CDS with the same product name
DBHLEIBD_01520 1.8e-124 S overlaps another CDS with the same product name
DBHLEIBD_01521 1.7e-99 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
DBHLEIBD_01522 2.2e-27 ytkL S Belongs to the UPF0173 family
DBHLEIBD_01523 3.6e-24 ytkL S Belongs to the UPF0173 family
DBHLEIBD_01524 3.9e-290 ybiT S ABC transporter, ATP-binding protein
DBHLEIBD_01525 1.5e-77 2.4.2.3 F Phosphorylase superfamily
DBHLEIBD_01526 9e-26
DBHLEIBD_01527 3.1e-113 dkg S reductase
DBHLEIBD_01529 2.5e-20 rimL 1.1.1.25 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DBHLEIBD_01530 2.3e-168 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DBHLEIBD_01531 1.5e-192 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DBHLEIBD_01532 2.1e-46 EGP Transmembrane secretion effector
DBHLEIBD_01533 5.2e-137 purR 2.4.2.7 F pur operon repressor
DBHLEIBD_01534 9.6e-52 adhR K helix_turn_helix, mercury resistance
DBHLEIBD_01535 3.9e-185 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DBHLEIBD_01536 6e-40 2.4.1.9 GH68 M MucBP domain
DBHLEIBD_01537 1.8e-155 amtB P ammonium transporter
DBHLEIBD_01538 3.7e-117 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DBHLEIBD_01539 6.6e-46 argR K Regulates arginine biosynthesis genes
DBHLEIBD_01540 1e-132 arcT 2.6.1.1 E Cys/Met metabolism PLP-dependent enzyme
DBHLEIBD_01541 5.7e-91 S Alpha/beta hydrolase of unknown function (DUF915)
DBHLEIBD_01542 1.2e-22 veg S Biofilm formation stimulator VEG
DBHLEIBD_01543 1.4e-132 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
DBHLEIBD_01544 3.4e-87 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DBHLEIBD_01545 1.7e-102 tatD L hydrolase, TatD family
DBHLEIBD_01546 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DBHLEIBD_01547 3.3e-127
DBHLEIBD_01548 1.8e-152 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
DBHLEIBD_01549 4.2e-43 VPA1512 ET Bacterial extracellular solute-binding proteins, family 3
DBHLEIBD_01550 3.9e-31 K Transcriptional regulator
DBHLEIBD_01551 2.4e-105 ybhR V ABC transporter
DBHLEIBD_01552 3.2e-82 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
DBHLEIBD_01553 5.5e-103 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
DBHLEIBD_01554 2.3e-171 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
DBHLEIBD_01555 9.3e-128 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DBHLEIBD_01556 1.4e-269 helD 3.6.4.12 L DNA helicase
DBHLEIBD_01558 1.3e-114 htpX O Belongs to the peptidase M48B family
DBHLEIBD_01559 3e-72 lemA S LemA family
DBHLEIBD_01560 1.1e-54 L phosphatase homologous to the C-terminal domain of histone macroH2A1
DBHLEIBD_01561 1.1e-45 yjcF K protein acetylation
DBHLEIBD_01563 3.3e-253 yfiC V ABC transporter
DBHLEIBD_01564 7.6e-223 lmrA V ABC transporter, ATP-binding protein
DBHLEIBD_01565 7.6e-35 K Bacterial regulatory proteins, tetR family
DBHLEIBD_01566 3.1e-244 yhcA V ABC transporter, ATP-binding protein
DBHLEIBD_01567 1.7e-222 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DBHLEIBD_01568 1e-146 G Transporter, major facilitator family protein
DBHLEIBD_01569 2.5e-89 lacX 5.1.3.3 G Aldose 1-epimerase
DBHLEIBD_01570 3.3e-142 hpk31 2.7.13.3 T Histidine kinase
DBHLEIBD_01571 1.4e-111 K response regulator
DBHLEIBD_01572 9.8e-89 patB 4.4.1.8 E Aminotransferase, class I
DBHLEIBD_01573 9e-93 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
DBHLEIBD_01574 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DBHLEIBD_01575 1.3e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
DBHLEIBD_01576 6.1e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DBHLEIBD_01577 1.9e-23 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
DBHLEIBD_01578 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DBHLEIBD_01579 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DBHLEIBD_01580 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
DBHLEIBD_01581 1.6e-55 ctsR K Belongs to the CtsR family
DBHLEIBD_01583 2.5e-119 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
DBHLEIBD_01584 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
DBHLEIBD_01585 1.7e-159 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
DBHLEIBD_01586 7.2e-186 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
DBHLEIBD_01587 1.7e-131 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
DBHLEIBD_01595 3.2e-92 yihY S Belongs to the UPF0761 family
DBHLEIBD_01596 6.2e-12 mltD CBM50 M Lysin motif
DBHLEIBD_01597 1.2e-152 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
DBHLEIBD_01598 1.2e-143 map 3.4.11.18 E Methionine Aminopeptidase
DBHLEIBD_01599 5.1e-54 fld C Flavodoxin
DBHLEIBD_01600 8.7e-53 gtcA S Teichoic acid glycosylation protein
DBHLEIBD_01601 0.0 S Bacterial membrane protein YfhO
DBHLEIBD_01602 5.2e-120 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
DBHLEIBD_01603 6.4e-122 S Sulfite exporter TauE/SafE
DBHLEIBD_01604 1.1e-70 K Sugar-specific transcriptional regulator TrmB
DBHLEIBD_01605 1.6e-168 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
DBHLEIBD_01606 1.3e-181 pepS E Thermophilic metalloprotease (M29)
DBHLEIBD_01607 2.2e-264 E Amino acid permease
DBHLEIBD_01608 4.1e-84 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
DBHLEIBD_01609 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
DBHLEIBD_01610 7.7e-79 galM 5.1.3.3 G Aldose 1-epimerase
DBHLEIBD_01611 3.8e-214 malT G Transporter, major facilitator family protein
DBHLEIBD_01612 1.2e-100 malR K Transcriptional regulator, LacI family
DBHLEIBD_01613 1.3e-279 kup P Transport of potassium into the cell
DBHLEIBD_01615 2e-20 S Domain of unknown function (DUF3284)
DBHLEIBD_01616 3.9e-160 yfmL L DEAD DEAH box helicase
DBHLEIBD_01617 5.4e-128 mocA S Oxidoreductase
DBHLEIBD_01618 3.4e-24 S Domain of unknown function (DUF4828)
DBHLEIBD_01619 1.5e-176 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
DBHLEIBD_01620 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
DBHLEIBD_01621 4.7e-194 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
DBHLEIBD_01622 3.1e-119 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
DBHLEIBD_01623 4e-156 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DBHLEIBD_01624 1.8e-265 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DBHLEIBD_01625 2.1e-220 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
DBHLEIBD_01626 2.2e-42 O ADP-ribosylglycohydrolase
DBHLEIBD_01627 4.6e-220 gdhA 1.4.1.4 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
DBHLEIBD_01628 3.8e-209 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
DBHLEIBD_01629 2.2e-34 K Acetyltransferase (GNAT) domain
DBHLEIBD_01630 1.7e-40
DBHLEIBD_01632 3.2e-160 mgtE P Acts as a magnesium transporter
DBHLEIBD_01633 7.6e-94 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
DBHLEIBD_01634 7.6e-117 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DBHLEIBD_01635 2.5e-94 yjbM 2.7.6.5 S RelA SpoT domain protein
DBHLEIBD_01636 9e-255 topB 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
DBHLEIBD_01637 3e-37 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
DBHLEIBD_01638 2.2e-193 pbuX F xanthine permease
DBHLEIBD_01639 9.7e-74 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
DBHLEIBD_01640 1.6e-61 acmC 3.2.1.96 NU mannosyl-glycoprotein
DBHLEIBD_01641 1.6e-63 S ECF transporter, substrate-specific component
DBHLEIBD_01642 1.6e-13 mleP S Sodium Bile acid symporter family
DBHLEIBD_01643 5.8e-249 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
DBHLEIBD_01644 2.4e-71 mleR K LysR family
DBHLEIBD_01645 3.6e-57 K transcriptional
DBHLEIBD_01646 3.8e-40 K Bacterial regulatory proteins, tetR family
DBHLEIBD_01647 8e-60 T Belongs to the universal stress protein A family
DBHLEIBD_01648 1.5e-42 K Copper transport repressor CopY TcrY
DBHLEIBD_01649 2.5e-34 3.2.1.18 GH33 M Rib/alpha-like repeat
DBHLEIBD_01650 4.2e-95 ypuA S Protein of unknown function (DUF1002)
DBHLEIBD_01651 1.5e-61 dedA 3.1.3.1 S SNARE associated Golgi protein
DBHLEIBD_01652 8.2e-160 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DBHLEIBD_01653 4.4e-18 yncA 2.3.1.79 S Maltose acetyltransferase
DBHLEIBD_01654 3.1e-206 yflS P Sodium:sulfate symporter transmembrane region
DBHLEIBD_01655 1.4e-198 frdC 1.3.5.4 C FAD binding domain
DBHLEIBD_01656 1.3e-236 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
DBHLEIBD_01657 1.5e-14 ybaN S Protein of unknown function (DUF454)
DBHLEIBD_01658 1.1e-176 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
DBHLEIBD_01659 1.5e-57 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
DBHLEIBD_01660 1.6e-96 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DBHLEIBD_01661 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
DBHLEIBD_01662 1.1e-71 ywlG S Belongs to the UPF0340 family
DBHLEIBD_01663 2.8e-157 C Oxidoreductase
DBHLEIBD_01664 1.1e-175 spoVK O PFAM ATPase family associated with various cellular activities (AAA)
DBHLEIBD_01665 8.1e-228 yfjM S Protein of unknown function DUF262
DBHLEIBD_01666 9e-75 S Domain of unknown function (DUF3841)
DBHLEIBD_01667 4.3e-57 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
DBHLEIBD_01668 8.4e-75 S Domain of unknown function (DUF4343)
DBHLEIBD_01669 5.7e-09
DBHLEIBD_01670 1.6e-14
DBHLEIBD_01671 1.9e-121 L Mrr N-terminal domain
DBHLEIBD_01672 2.6e-56 S UPF0489 domain
DBHLEIBD_01674 4.4e-34 3.1.21.3 V Type I restriction modification DNA specificity domain
DBHLEIBD_01675 5.1e-24
DBHLEIBD_01676 0.0 3.1.11.5 L Psort location Cytoplasmic, score 8.87
DBHLEIBD_01677 2.1e-48 L COG COG1961 Site-specific recombinases, DNA invertase Pin homologs
DBHLEIBD_01678 1.2e-52 L Resolvase, N terminal domain
DBHLEIBD_01679 2.2e-209 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DBHLEIBD_01680 3.4e-146 yegS 2.7.1.107 G Lipid kinase
DBHLEIBD_01681 1.9e-256 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DBHLEIBD_01682 1.8e-233 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
DBHLEIBD_01683 7.6e-38 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DBHLEIBD_01684 3.5e-160 camS S sex pheromone
DBHLEIBD_01685 1.1e-278 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DBHLEIBD_01686 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
DBHLEIBD_01687 3.8e-146 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DBHLEIBD_01694 6.3e-54 S Protein of unknown function (DUF4256)
DBHLEIBD_01695 8.2e-127 metQ M Belongs to the nlpA lipoprotein family
DBHLEIBD_01696 2.4e-31 metI U ABC transporter permease
DBHLEIBD_01697 6.2e-151 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DBHLEIBD_01699 1e-261 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
DBHLEIBD_01700 8.1e-172 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
DBHLEIBD_01701 1e-106 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
DBHLEIBD_01702 3.7e-82 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
DBHLEIBD_01703 3e-84 drgA C nitroreductase
DBHLEIBD_01704 5.7e-134 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
DBHLEIBD_01705 1.3e-69 metI P ABC transporter permease
DBHLEIBD_01706 2.6e-149 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DBHLEIBD_01707 1.8e-108 metQ1 P Belongs to the nlpA lipoprotein family
DBHLEIBD_01708 2.7e-144 2.1.1.14 E methionine synthase, vitamin-B12 independent
DBHLEIBD_01709 1e-45 yphJ 4.1.1.44 S decarboxylase
DBHLEIBD_01710 1.4e-58 yphH S Cupin domain
DBHLEIBD_01711 5.7e-48 C Flavodoxin
DBHLEIBD_01712 2.7e-56 S CAAX protease self-immunity
DBHLEIBD_01713 1.5e-102 pgm3 G phosphoglycerate mutase
DBHLEIBD_01714 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
DBHLEIBD_01715 1.4e-224 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DBHLEIBD_01716 1.1e-54 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DBHLEIBD_01717 4.4e-67 M ErfK YbiS YcfS YnhG
DBHLEIBD_01718 3.9e-107 XK27_08845 S ABC transporter, ATP-binding protein
DBHLEIBD_01719 4.3e-113 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
DBHLEIBD_01720 3.5e-132 ABC-SBP S ABC transporter
DBHLEIBD_01721 1.7e-159 potD P ABC transporter
DBHLEIBD_01722 1.7e-103 potC U Binding-protein-dependent transport system inner membrane component
DBHLEIBD_01723 1.5e-120 potB P ABC transporter permease
DBHLEIBD_01724 8.2e-167 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
DBHLEIBD_01725 1.4e-98 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
DBHLEIBD_01726 2.2e-260 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
DBHLEIBD_01727 1.5e-235 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DBHLEIBD_01728 3.9e-13 S Enterocin A Immunity
DBHLEIBD_01730 2.2e-16 pspC KT PspC domain
DBHLEIBD_01731 4.1e-16 S Putative adhesin
DBHLEIBD_01732 4.2e-19 XK27_06920 S Protein of unknown function (DUF1700)
DBHLEIBD_01733 1.3e-38 K transcriptional regulator PadR family
DBHLEIBD_01734 1.5e-46 S CRISPR-associated protein (Cas_Csn2)
DBHLEIBD_01735 6.5e-37 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DBHLEIBD_01736 7.2e-108 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DBHLEIBD_01737 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
DBHLEIBD_01738 1e-47 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
DBHLEIBD_01739 3.1e-75 ung2 3.2.2.27 L Uracil-DNA glycosylase
DBHLEIBD_01740 1.9e-164 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DBHLEIBD_01741 1.4e-129 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DBHLEIBD_01742 2.7e-70 mltD CBM50 M NlpC P60 family protein
DBHLEIBD_01743 3.2e-52 manO S Domain of unknown function (DUF956)
DBHLEIBD_01744 1e-146 manN G system, mannose fructose sorbose family IID component
DBHLEIBD_01745 6.4e-116 manY G PTS system sorbose-specific iic component
DBHLEIBD_01746 5.3e-152 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
DBHLEIBD_01747 2.6e-79 rbsB G sugar-binding domain protein
DBHLEIBD_01748 1.2e-103 baeS T Histidine kinase
DBHLEIBD_01749 3e-79 baeR K Bacterial regulatory proteins, luxR family
DBHLEIBD_01750 2.6e-119 G Bacterial extracellular solute-binding protein
DBHLEIBD_01751 2.3e-39 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DBHLEIBD_01752 4.2e-32 merR K MerR HTH family regulatory protein
DBHLEIBD_01753 2.7e-197 lmrB EGP Major facilitator Superfamily
DBHLEIBD_01754 1.3e-32 S Domain of unknown function (DUF4811)
DBHLEIBD_01755 8.2e-84 G Phosphoglycerate mutase family
DBHLEIBD_01756 5e-60 yceE S haloacid dehalogenase-like hydrolase
DBHLEIBD_01757 8.4e-73 glcR K DeoR C terminal sensor domain
DBHLEIBD_01758 2.4e-93 dacA 3.4.16.4 M Belongs to the peptidase S11 family
DBHLEIBD_01759 1.1e-182 lmrB EGP Major facilitator Superfamily
DBHLEIBD_01760 1.1e-282 fruA 3.2.1.1, 3.2.1.65, 3.2.1.80 GH13,GH32 GN Fructan beta-fructosidase
DBHLEIBD_01761 3.3e-52 bioY S BioY family
DBHLEIBD_01762 9.9e-93 S Predicted membrane protein (DUF2207)
DBHLEIBD_01763 1.4e-19
DBHLEIBD_01764 4e-38 M Glycosyltransferase like family 2
DBHLEIBD_01765 1.7e-53 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
DBHLEIBD_01766 1.7e-58 ktrA P TrkA-N domain
DBHLEIBD_01767 1.6e-114 ntpJ P Potassium uptake protein
DBHLEIBD_01768 7.7e-183 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
DBHLEIBD_01769 5.2e-281 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
DBHLEIBD_01770 1.2e-216 scrB 3.2.1.26 GH32 G invertase
DBHLEIBD_01771 2.3e-147 scrR K helix_turn _helix lactose operon repressor
DBHLEIBD_01772 7.2e-38 L hmm pf00665
DBHLEIBD_01773 1.8e-49 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
DBHLEIBD_01774 8.7e-51 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
DBHLEIBD_01775 3.4e-275 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
DBHLEIBD_01776 3.9e-133 coaA 2.7.1.33 F Pantothenic acid kinase
DBHLEIBD_01777 1.7e-44 E GDSL-like Lipase/Acylhydrolase
DBHLEIBD_01778 2.3e-112 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
DBHLEIBD_01779 1.6e-189 glnPH2 P ABC transporter permease
DBHLEIBD_01780 2.1e-213 yjeM E Amino Acid
DBHLEIBD_01781 3.9e-32 yvdC S MazG nucleotide pyrophosphohydrolase domain
DBHLEIBD_01782 2.5e-137 tetA EGP Major facilitator Superfamily
DBHLEIBD_01783 1.3e-62 S Glycosyltransferase like family 2
DBHLEIBD_01784 1.5e-117 cps1D M Domain of unknown function (DUF4422)
DBHLEIBD_01785 2.1e-37 S CAAX protease self-immunity
DBHLEIBD_01786 9.1e-89 yvyE 3.4.13.9 S YigZ family
DBHLEIBD_01787 2.3e-58 S Haloacid dehalogenase-like hydrolase
DBHLEIBD_01788 4.5e-154 EGP Major facilitator Superfamily
DBHLEIBD_01790 1.5e-67 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
DBHLEIBD_01791 2.1e-27 yraB K transcriptional regulator
DBHLEIBD_01792 2.9e-89 S NADPH-dependent FMN reductase
DBHLEIBD_01793 8.8e-102 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
DBHLEIBD_01794 1.5e-55 S ECF transporter, substrate-specific component
DBHLEIBD_01795 2.8e-103 znuB U ABC 3 transport family
DBHLEIBD_01796 2.9e-98 fhuC P ABC transporter
DBHLEIBD_01797 1e-103 psaA P Belongs to the bacterial solute-binding protein 9 family
DBHLEIBD_01798 1.5e-38
DBHLEIBD_01799 7.3e-14 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
DBHLEIBD_01800 4.2e-53 XK27_01040 S Protein of unknown function (DUF1129)
DBHLEIBD_01801 2.4e-190 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
DBHLEIBD_01802 1.8e-24 yyzM S Bacterial protein of unknown function (DUF951)
DBHLEIBD_01803 9.1e-108 spo0J K Belongs to the ParB family
DBHLEIBD_01804 6.5e-118 soj D Sporulation initiation inhibitor
DBHLEIBD_01805 9.5e-68 noc K Belongs to the ParB family
DBHLEIBD_01806 3.6e-102 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
DBHLEIBD_01807 1.2e-126 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
DBHLEIBD_01808 1.2e-108 3.1.4.46 C phosphodiesterase
DBHLEIBD_01809 0.0 pacL 3.6.3.8 P P-type ATPase
DBHLEIBD_01810 1.5e-60 yvdD 3.2.2.10 S Possible lysine decarboxylase
DBHLEIBD_01811 6.8e-72 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
DBHLEIBD_01813 5.2e-63 srtA 3.4.22.70 M sortase family
DBHLEIBD_01814 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
DBHLEIBD_01815 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
DBHLEIBD_01816 3.7e-34
DBHLEIBD_01817 4.5e-140 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DBHLEIBD_01818 4e-157 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DBHLEIBD_01819 6.6e-97 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DBHLEIBD_01820 1.1e-157 manA 5.3.1.8 G mannose-6-phosphate isomerase
DBHLEIBD_01821 4.3e-39 ybjQ S Belongs to the UPF0145 family
DBHLEIBD_01822 5.7e-08
DBHLEIBD_01823 1.8e-95 V ABC transporter, ATP-binding protein
DBHLEIBD_01824 4e-41 gntR1 K Transcriptional regulator, GntR family
DBHLEIBD_01825 2.4e-185 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
DBHLEIBD_01826 2.8e-65 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DBHLEIBD_01827 1.1e-261 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
DBHLEIBD_01828 2.2e-107 terC P Integral membrane protein TerC family
DBHLEIBD_01829 2.1e-38 K Transcriptional regulator
DBHLEIBD_01830 5.7e-96 tcyA ET Belongs to the bacterial solute-binding protein 3 family
DBHLEIBD_01831 2e-100 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
DBHLEIBD_01832 4.5e-102 tcyB E ABC transporter
DBHLEIBD_01834 2.3e-302 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
DBHLEIBD_01835 4e-210 mtlR K Mga helix-turn-helix domain
DBHLEIBD_01836 3e-164 yjcE P Sodium proton antiporter
DBHLEIBD_01837 5.5e-103 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
DBHLEIBD_01838 1.4e-49 dhaM 2.7.1.121 S PTS system fructose IIA component
DBHLEIBD_01839 3.3e-69 dhaL 2.7.1.121 S Dak2
DBHLEIBD_01840 7.6e-151 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
DBHLEIBD_01841 1.9e-114 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
DBHLEIBD_01842 1.7e-61 K Bacterial regulatory proteins, tetR family
DBHLEIBD_01843 1.9e-208 brnQ U Component of the transport system for branched-chain amino acids
DBHLEIBD_01845 7e-110 endA F DNA RNA non-specific endonuclease
DBHLEIBD_01846 1.8e-75 XK27_02070 S Nitroreductase family
DBHLEIBD_01847 2.4e-193 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
DBHLEIBD_01848 3.5e-33 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
DBHLEIBD_01849 6.8e-293 lai 4.2.1.53 S Myosin-crossreactive antigen
DBHLEIBD_01850 2.1e-113 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
DBHLEIBD_01851 1e-57 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
DBHLEIBD_01852 5.1e-77 azlC E branched-chain amino acid
DBHLEIBD_01853 4.4e-31 azlD S Branched-chain amino acid transport protein (AzlD)
DBHLEIBD_01854 1.5e-56 ohrR K helix_turn_helix multiple antibiotic resistance protein
DBHLEIBD_01855 1.6e-55 jag S R3H domain protein
DBHLEIBD_01856 2.2e-125 sip L Belongs to the 'phage' integrase family
DBHLEIBD_01857 4.2e-24 K Cro/C1-type HTH DNA-binding domain
DBHLEIBD_01858 5.3e-08 S Helix-turn-helix domain
DBHLEIBD_01859 1.6e-30 S Phage regulatory protein Rha (Phage_pRha)
DBHLEIBD_01860 4.5e-53 K Transcriptional regulator C-terminal region
DBHLEIBD_01861 2.7e-44 thiT S Thiamine transporter protein (Thia_YuaJ)
DBHLEIBD_01862 2e-285 pepO 3.4.24.71 O Peptidase family M13
DBHLEIBD_01863 5e-111 dat 2.6.1.21 EH PFAM aminotransferase, class IV
DBHLEIBD_01864 2.1e-07 yvaZ S SdpI/YhfL protein family
DBHLEIBD_01865 6.6e-71 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
DBHLEIBD_01866 6.7e-47 hmpT S ECF-type riboflavin transporter, S component
DBHLEIBD_01867 1.3e-40 wecD K Acetyltransferase GNAT Family
DBHLEIBD_01869 1.3e-37 aguA_2 3.5.3.12 E Porphyromonas-type peptidyl-arginine deiminase
DBHLEIBD_01870 7.6e-58 XK27_06780 V ABC transporter permease
DBHLEIBD_01871 1.2e-179 XK27_06780 V ABC transporter permease
DBHLEIBD_01872 1.2e-94 XK27_06785 V ABC transporter, ATP-binding protein
DBHLEIBD_01873 3.2e-34 tetR K transcriptional regulator
DBHLEIBD_01874 1.1e-18
DBHLEIBD_01875 2e-12 3.1.3.48 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DBHLEIBD_01877 9.8e-72 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DBHLEIBD_01878 8.4e-119 ytbE S reductase
DBHLEIBD_01879 4.2e-43 ytcD K HxlR-like helix-turn-helix
DBHLEIBD_01880 1.9e-101 ybbM S Uncharacterised protein family (UPF0014)
DBHLEIBD_01881 2.6e-67 ybbL S ABC transporter
DBHLEIBD_01882 6.2e-163 oxlT P Major Facilitator Superfamily
DBHLEIBD_01883 6.2e-53 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DBHLEIBD_01884 4.1e-47 S Short repeat of unknown function (DUF308)
DBHLEIBD_01885 3e-30 tetR K Transcriptional regulator C-terminal region
DBHLEIBD_01886 1.2e-150 yfeX P Peroxidase
DBHLEIBD_01887 8.6e-17 S Protein of unknown function (DUF3021)
DBHLEIBD_01888 4.5e-39 K LytTr DNA-binding domain
DBHLEIBD_01889 9e-114 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
DBHLEIBD_01890 3.2e-208 mmuP E amino acid
DBHLEIBD_01891 9.2e-16 psiE S Phosphate-starvation-inducible E
DBHLEIBD_01892 2.2e-155 oppF P Belongs to the ABC transporter superfamily
DBHLEIBD_01893 1.3e-180 oppD P Belongs to the ABC transporter superfamily
DBHLEIBD_01894 4.4e-170 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
DBHLEIBD_01895 4.6e-142 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
DBHLEIBD_01896 4.7e-203 oppA E ABC transporter, substratebinding protein
DBHLEIBD_01897 2.3e-217 yifK E Amino acid permease
DBHLEIBD_01898 1.1e-85 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DBHLEIBD_01899 3.9e-57 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
DBHLEIBD_01900 1.4e-65 pgm3 G phosphoglycerate mutase family
DBHLEIBD_01901 2.1e-250 ctpA 3.6.3.54 P P-type ATPase
DBHLEIBD_01902 3.3e-21 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
DBHLEIBD_01903 1.5e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
DBHLEIBD_01904 8.2e-149 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
DBHLEIBD_01905 1.2e-21 K transcriptional regulator
DBHLEIBD_01906 5e-77 hchA S intracellular protease amidase
DBHLEIBD_01907 2.8e-135 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
DBHLEIBD_01908 1.8e-112 lacI3 K helix_turn _helix lactose operon repressor
DBHLEIBD_01909 4.2e-231 malL 3.2.1.10 GH13 G Psort location Cytoplasmic, score
DBHLEIBD_01910 7.5e-39 2.7.1.191 G PTS system fructose IIA component
DBHLEIBD_01911 3.2e-123 G PTS system mannose/fructose/sorbose family IID component
DBHLEIBD_01912 4.4e-101 G PTS system sorbose-specific iic component
DBHLEIBD_01913 5.8e-64 2.7.1.191 G PTS system sorbose subfamily IIB component
DBHLEIBD_01914 1.9e-80 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
DBHLEIBD_01915 4.3e-140 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
DBHLEIBD_01916 9.9e-201 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
DBHLEIBD_01917 2.9e-117 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
DBHLEIBD_01918 9e-198 1.3.5.4 C FMN_bind
DBHLEIBD_01919 1.7e-56 3.1.3.48 K Transcriptional regulator
DBHLEIBD_01920 1.2e-159 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
DBHLEIBD_01921 5.3e-197 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
DBHLEIBD_01922 2.4e-73 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
DBHLEIBD_01923 1.1e-129 yxjG 2.1.1.14 E Cobalamin-independent synthase, Catalytic domain
DBHLEIBD_01924 2.7e-100 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
DBHLEIBD_01925 2.5e-82 S Belongs to the UPF0246 family
DBHLEIBD_01928 1.6e-59 ykhA 3.1.2.20 I Thioesterase superfamily
DBHLEIBD_01929 1.5e-156 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
DBHLEIBD_01931 9.6e-231 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DBHLEIBD_01932 4e-64 C FMN binding
DBHLEIBD_01933 1.4e-206 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
DBHLEIBD_01934 2.9e-57 rplI J Binds to the 23S rRNA
DBHLEIBD_01935 1.1e-262 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
DBHLEIBD_01936 6.1e-07
DBHLEIBD_01940 7.8e-136 S interspecies interaction between organisms
DBHLEIBD_01941 1.2e-207 G glycerol-3-phosphate transporter
DBHLEIBD_01942 5.8e-72 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DBHLEIBD_01943 4.8e-145 htrA 3.4.21.107 O serine protease
DBHLEIBD_01944 2.2e-116 vicX 3.1.26.11 S domain protein
DBHLEIBD_01945 6.8e-30 yyaQ S YjbR
DBHLEIBD_01946 5.6e-80 yycI S YycH protein
DBHLEIBD_01947 7.9e-103 yycH S YycH protein
DBHLEIBD_01948 1.5e-272 vicK 2.7.13.3 T Histidine kinase
DBHLEIBD_01949 9e-114 K response regulator
DBHLEIBD_01950 6.1e-106 yxeH S hydrolase
DBHLEIBD_01951 1e-227 V ABC transporter transmembrane region
DBHLEIBD_01952 6.9e-216 XK27_09600 V ABC transporter, ATP-binding protein
DBHLEIBD_01953 7.1e-32 K Transcriptional regulator, MarR family
DBHLEIBD_01954 8.9e-174 S Putative peptidoglycan binding domain
DBHLEIBD_01955 3.8e-62 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
DBHLEIBD_01956 3.6e-138 gldA 1.1.1.6 C Iron-containing alcohol dehydrogenase
DBHLEIBD_01957 1.5e-179 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
DBHLEIBD_01958 3.1e-106 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
DBHLEIBD_01959 2.1e-223 pepF E Oligopeptidase F
DBHLEIBD_01960 3.7e-96 yicL EG EamA-like transporter family
DBHLEIBD_01961 7e-69 2.3.1.178 J Acetyltransferase (GNAT) domain
DBHLEIBD_01962 1e-166 yjjP S Putative threonine/serine exporter
DBHLEIBD_01963 1.7e-24 S PFAM Archaeal ATPase
DBHLEIBD_01964 5.7e-59 S PFAM Archaeal ATPase
DBHLEIBD_01965 1.3e-169 ydfJ EGP Sugar (and other) transporter
DBHLEIBD_01966 2.6e-138 rspB 1.1.1.380 C Zinc-binding dehydrogenase
DBHLEIBD_01967 1.5e-173 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
DBHLEIBD_01968 2.5e-207 mtlD 1.1.1.17, 1.1.1.57 G Mannitol dehydrogenase C-terminal domain
DBHLEIBD_01969 1.5e-49 kdgR K FCD domain
DBHLEIBD_01970 6.5e-113 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
DBHLEIBD_01971 3.3e-62 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
DBHLEIBD_01972 4.8e-109 glcU U sugar transport
DBHLEIBD_01973 1e-14 yobS K transcriptional regulator
DBHLEIBD_01974 2e-153 mdtG EGP Major facilitator Superfamily
DBHLEIBD_01975 1.2e-105 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
DBHLEIBD_01976 4.2e-223 yxbA 6.3.1.12 S ATP-grasp enzyme
DBHLEIBD_01977 2.8e-229 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DBHLEIBD_01978 9.5e-18 yneR
DBHLEIBD_01979 2.8e-247 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
DBHLEIBD_01980 1.6e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
DBHLEIBD_01981 5.1e-59 yiiE S Protein of unknown function (DUF1211)
DBHLEIBD_01982 0.0 asnB 6.3.5.4 E Asparagine synthase
DBHLEIBD_01983 7.4e-64 D peptidase
DBHLEIBD_01984 7.3e-117 S Glycosyl transferase family 2
DBHLEIBD_01985 2.4e-108 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
DBHLEIBD_01986 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DBHLEIBD_01987 3.3e-63 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
DBHLEIBD_01988 4.8e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
DBHLEIBD_01989 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DBHLEIBD_01990 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DBHLEIBD_01991 1.2e-152 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DBHLEIBD_01992 9e-20 yaaA S S4 domain protein YaaA
DBHLEIBD_01993 8.6e-159 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
DBHLEIBD_01994 2.1e-204 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DBHLEIBD_01995 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
DBHLEIBD_01996 2.2e-49 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
DBHLEIBD_01997 3.1e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DBHLEIBD_01998 1.1e-199 nupG F Nucleoside
DBHLEIBD_01999 1.3e-121 MA20_14895 S Conserved hypothetical protein 698
DBHLEIBD_02000 1.7e-53 K LysR substrate binding domain
DBHLEIBD_02001 9.6e-09
DBHLEIBD_02002 3.2e-67 yxkH G Polysaccharide deacetylase
DBHLEIBD_02003 9e-30 yqkB S Belongs to the HesB IscA family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)