ORF_ID e_value Gene_name EC_number CAZy COGs Description
MNLFNLIM_00001 7e-51 yeaL S Protein of unknown function (DUF441)
MNLFNLIM_00002 1.5e-58 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MNLFNLIM_00003 5.8e-100 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MNLFNLIM_00004 1.1e-56 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MNLFNLIM_00005 4.5e-58 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MNLFNLIM_00006 2.3e-36 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MNLFNLIM_00007 7.8e-218 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MNLFNLIM_00008 7e-79 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MNLFNLIM_00009 1e-122 xerC D Belongs to the 'phage' integrase family. XerC subfamily
MNLFNLIM_00010 2.5e-177 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
MNLFNLIM_00011 1.4e-101 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
MNLFNLIM_00012 3.1e-71
MNLFNLIM_00015 1e-12
MNLFNLIM_00016 1.6e-42 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MNLFNLIM_00017 2.9e-27 ysxB J Cysteine protease Prp
MNLFNLIM_00018 4.9e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
MNLFNLIM_00021 2.2e-08 S Protein of unknown function (DUF2922)
MNLFNLIM_00023 2.9e-16 K DNA-templated transcription, initiation
MNLFNLIM_00025 1.6e-65 H Methyltransferase domain
MNLFNLIM_00026 6.9e-39 wecD M Acetyltransferase (GNAT) family
MNLFNLIM_00028 7.3e-27 ybl78 L Conserved phage C-terminus (Phg_2220_C)
MNLFNLIM_00029 5.7e-41 S Protein of unknown function (DUF1211)
MNLFNLIM_00031 5e-71 1.1.1.1 C Zinc-binding dehydrogenase
MNLFNLIM_00032 3.6e-39 K Transcriptional regulator
MNLFNLIM_00033 7.5e-83 qorB 1.6.5.2 GM NmrA-like family
MNLFNLIM_00036 5.6e-126 M Glycosyl transferases group 1
MNLFNLIM_00037 6.9e-65 M Glycosyl transferases group 1
MNLFNLIM_00038 9.8e-180 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MNLFNLIM_00039 6.1e-146 lspL 5.1.3.6 GM RmlD substrate binding domain
MNLFNLIM_00040 6.9e-103 cps2I S Psort location CytoplasmicMembrane, score
MNLFNLIM_00041 4.5e-61 cps1B GT2,GT4 M Glycosyl transferases group 1
MNLFNLIM_00042 8.8e-116 S Glycosyltransferase WbsX
MNLFNLIM_00043 1.6e-52
MNLFNLIM_00045 2.5e-57 pglI 2.4.1.293 GT2 M Glycosyltransferase like family 2
MNLFNLIM_00046 1.7e-42 GT2 V Glycosyl transferase, family 2
MNLFNLIM_00047 4.4e-75 M Glycosyltransferase Family 4
MNLFNLIM_00048 9.3e-60 gtf1 2.4.1.52 GT4 M glycosyl transferase group 1
MNLFNLIM_00050 8.1e-80 gtf1 2.4.1.52 GT4 M glycosyl transferase group 1
MNLFNLIM_00051 1.9e-123 2.4.1.52 GT4 M Glycosyl transferases group 1
MNLFNLIM_00052 2.2e-25 pglD 2.3.1.203 S Bacterial transferase hexapeptide (six repeats)
MNLFNLIM_00053 4.8e-77 epsL M Bacterial sugar transferase
MNLFNLIM_00054 3.8e-165 2.6.1.102 M Belongs to the DegT DnrJ EryC1 family
MNLFNLIM_00055 9.8e-127 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
MNLFNLIM_00056 4.9e-89 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM CoA-binding domain
MNLFNLIM_00057 9.4e-65 cpsD D AAA domain
MNLFNLIM_00058 1.8e-48 cps4C M Chain length determinant protein
MNLFNLIM_00059 6.7e-42 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
MNLFNLIM_00060 8.5e-177 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
MNLFNLIM_00061 4.8e-81
MNLFNLIM_00062 1.8e-83 yjfP S COG1073 Hydrolases of the alpha beta superfamily
MNLFNLIM_00063 5.1e-113 yitU 3.1.3.104 S hydrolase
MNLFNLIM_00064 3e-61 speG J Acetyltransferase (GNAT) domain
MNLFNLIM_00065 2.4e-189 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MNLFNLIM_00066 1.1e-23 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
MNLFNLIM_00067 1.9e-203 pipD E Dipeptidase
MNLFNLIM_00068 2.3e-45
MNLFNLIM_00069 3.5e-64 K helix_turn_helix, arabinose operon control protein
MNLFNLIM_00070 8.9e-54 S Membrane
MNLFNLIM_00071 0.0 rafA 3.2.1.22 G alpha-galactosidase
MNLFNLIM_00072 5.9e-308 L Helicase C-terminal domain protein
MNLFNLIM_00073 1.9e-50 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
MNLFNLIM_00074 1.7e-38 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
MNLFNLIM_00075 2.4e-113 2.7.7.65 T diguanylate cyclase activity
MNLFNLIM_00076 0.0 ydaN S Bacterial cellulose synthase subunit
MNLFNLIM_00077 7.7e-201 ydaM M Glycosyl transferase family group 2
MNLFNLIM_00078 2.6e-206 S Protein conserved in bacteria
MNLFNLIM_00079 9.3e-182
MNLFNLIM_00080 1.7e-129 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
MNLFNLIM_00081 8.1e-43 2.7.7.65 T GGDEF domain
MNLFNLIM_00082 1.8e-124 pbuO_1 S Permease family
MNLFNLIM_00083 3.7e-11 pbuO_1 S Permease family
MNLFNLIM_00084 2.5e-156 ndh 1.6.99.3 C NADH dehydrogenase
MNLFNLIM_00085 3.3e-105 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
MNLFNLIM_00086 6.2e-97 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MNLFNLIM_00087 3.6e-220 cydD CO ABC transporter transmembrane region
MNLFNLIM_00088 7.8e-204 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MNLFNLIM_00089 5.6e-141 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
MNLFNLIM_00090 3e-193 cydA 1.10.3.14 C ubiquinol oxidase
MNLFNLIM_00091 2.6e-159 asnA 6.3.1.1 F aspartate--ammonia ligase
MNLFNLIM_00092 5.7e-29 xlyB 3.5.1.28 CBM50 M LysM domain
MNLFNLIM_00093 2.3e-19 glpE P Rhodanese Homology Domain
MNLFNLIM_00094 2.1e-48 lytE M LysM domain protein
MNLFNLIM_00095 4.8e-93 T Calcineurin-like phosphoesterase superfamily domain
MNLFNLIM_00096 9.6e-85 2.7.7.12 C Domain of unknown function (DUF4931)
MNLFNLIM_00098 3.3e-74 draG O ADP-ribosylglycohydrolase
MNLFNLIM_00099 4.4e-91 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MNLFNLIM_00100 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MNLFNLIM_00101 5.1e-62 divIVA D DivIVA domain protein
MNLFNLIM_00102 7.7e-82 ylmH S S4 domain protein
MNLFNLIM_00103 3e-19 yggT S YGGT family
MNLFNLIM_00104 5e-33 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MNLFNLIM_00105 2.9e-179 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MNLFNLIM_00106 1.6e-191 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MNLFNLIM_00107 5.7e-62 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MNLFNLIM_00108 6.8e-153 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MNLFNLIM_00109 2.9e-185 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MNLFNLIM_00110 8.7e-136 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MNLFNLIM_00111 6.9e-282 ftsI 3.4.16.4 M Penicillin-binding Protein
MNLFNLIM_00112 2.5e-11 ftsL D cell division protein FtsL
MNLFNLIM_00113 3.6e-142 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MNLFNLIM_00114 5.2e-64 mraZ K Belongs to the MraZ family
MNLFNLIM_00115 5.8e-08 S Protein of unknown function (DUF3397)
MNLFNLIM_00116 2.7e-155 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
MNLFNLIM_00118 7.5e-100 D Alpha beta
MNLFNLIM_00119 1.4e-108 aatB ET ABC transporter substrate-binding protein
MNLFNLIM_00120 1.1e-89 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MNLFNLIM_00121 1.9e-94 glnP P ABC transporter permease
MNLFNLIM_00122 3.1e-126 minD D Belongs to the ParA family
MNLFNLIM_00123 3.2e-76 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MNLFNLIM_00124 4.4e-54 mreD M rod shape-determining protein MreD
MNLFNLIM_00125 2.1e-88 mreC M Involved in formation and maintenance of cell shape
MNLFNLIM_00126 3.6e-156 mreB D cell shape determining protein MreB
MNLFNLIM_00127 4.5e-21 K Cold shock
MNLFNLIM_00128 6.2e-80 radC L DNA repair protein
MNLFNLIM_00129 2.4e-136 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MNLFNLIM_00130 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MNLFNLIM_00131 4.2e-196 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MNLFNLIM_00132 2.2e-162 iscS2 2.8.1.7 E Aminotransferase class V
MNLFNLIM_00133 9.3e-173 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MNLFNLIM_00134 1.6e-55 ytsP 1.8.4.14 T GAF domain-containing protein
MNLFNLIM_00135 7.5e-101 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MNLFNLIM_00136 5.9e-24 yueI S Protein of unknown function (DUF1694)
MNLFNLIM_00137 5.8e-188 rarA L recombination factor protein RarA
MNLFNLIM_00139 3.2e-73 usp6 T universal stress protein
MNLFNLIM_00140 1.2e-52 tag 3.2.2.20 L glycosylase
MNLFNLIM_00141 5e-199 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MNLFNLIM_00142 5e-124 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MNLFNLIM_00145 1.8e-45 yviA S Protein of unknown function (DUF421)
MNLFNLIM_00147 2.6e-278 pbp2b 3.4.16.4 M Penicillin-binding Protein
MNLFNLIM_00148 8.4e-298 S membrane
MNLFNLIM_00149 9.6e-81 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MNLFNLIM_00150 9.9e-218 recJ L Single-stranded-DNA-specific exonuclease RecJ
MNLFNLIM_00151 1.7e-100 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
MNLFNLIM_00152 9.8e-140 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MNLFNLIM_00154 1.4e-16
MNLFNLIM_00155 8.1e-199 oatA I Acyltransferase
MNLFNLIM_00156 2.2e-214 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MNLFNLIM_00157 2.8e-305 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MNLFNLIM_00158 1.2e-140 hprA 1.1.1.29 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MNLFNLIM_00161 4.4e-41 S Phosphoesterase
MNLFNLIM_00162 5.5e-72 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MNLFNLIM_00163 1.1e-60 yslB S Protein of unknown function (DUF2507)
MNLFNLIM_00164 6.4e-40 trxA O Belongs to the thioredoxin family
MNLFNLIM_00165 7.2e-309 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MNLFNLIM_00166 1.6e-17 cvpA S Colicin V production protein
MNLFNLIM_00167 1.4e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MNLFNLIM_00168 1.9e-33 yrzB S Belongs to the UPF0473 family
MNLFNLIM_00169 2.3e-59 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MNLFNLIM_00170 2.1e-36 yrzL S Belongs to the UPF0297 family
MNLFNLIM_00171 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MNLFNLIM_00172 6.7e-187 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MNLFNLIM_00173 1.2e-121 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
MNLFNLIM_00174 7.5e-13
MNLFNLIM_00175 3.9e-146 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MNLFNLIM_00176 1.4e-64 yrjD S LUD domain
MNLFNLIM_00177 1.1e-244 lutB C 4Fe-4S dicluster domain
MNLFNLIM_00178 6.9e-117 lutA C Cysteine-rich domain
MNLFNLIM_00179 2e-208 yfnA E Amino Acid
MNLFNLIM_00181 4.3e-61 uspA T universal stress protein
MNLFNLIM_00183 1.4e-12 yajC U Preprotein translocase
MNLFNLIM_00184 7.8e-208 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MNLFNLIM_00185 7.9e-183 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MNLFNLIM_00186 8.2e-153 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MNLFNLIM_00187 3.6e-71 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MNLFNLIM_00188 9.6e-211 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MNLFNLIM_00189 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MNLFNLIM_00190 7.6e-182 rny S Endoribonuclease that initiates mRNA decay
MNLFNLIM_00191 2.3e-159 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MNLFNLIM_00192 8e-84 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MNLFNLIM_00193 8.5e-64 ymfM S Helix-turn-helix domain
MNLFNLIM_00194 4.9e-91 IQ Enoyl-(Acyl carrier protein) reductase
MNLFNLIM_00195 9.3e-149 ymfH S Peptidase M16
MNLFNLIM_00196 2e-108 ymfF S Peptidase M16 inactive domain protein
MNLFNLIM_00197 6.8e-288 ftsK D Belongs to the FtsK SpoIIIE SftA family
MNLFNLIM_00198 4.4e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MNLFNLIM_00199 5.8e-99 rrmA 2.1.1.187 H Methyltransferase
MNLFNLIM_00200 4.9e-61 ybaK J Aminoacyl-tRNA editing domain
MNLFNLIM_00201 1.7e-163 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MNLFNLIM_00202 4.8e-198 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MNLFNLIM_00203 2.9e-94 S Bacterial membrane protein, YfhO
MNLFNLIM_00205 2.3e-19 cutC P Participates in the control of copper homeostasis
MNLFNLIM_00206 4.9e-129 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
MNLFNLIM_00207 5.8e-29 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
MNLFNLIM_00208 2.6e-226 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MNLFNLIM_00209 5.3e-68 ybbR S YbbR-like protein
MNLFNLIM_00210 8.5e-127 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MNLFNLIM_00211 2.4e-71 S Protein of unknown function (DUF1361)
MNLFNLIM_00212 6e-115 murB 1.3.1.98 M Cell wall formation
MNLFNLIM_00213 3e-69 dnaQ 2.7.7.7 L DNA polymerase III
MNLFNLIM_00214 4.2e-56 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
MNLFNLIM_00215 2e-143 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MNLFNLIM_00216 8.9e-106 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MNLFNLIM_00217 2.4e-116 ycsE S Sucrose-6F-phosphate phosphohydrolase
MNLFNLIM_00218 3.1e-42 yxjI
MNLFNLIM_00219 6.9e-70 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MNLFNLIM_00220 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MNLFNLIM_00221 2.8e-19 secG U Preprotein translocase
MNLFNLIM_00222 1e-178 clcA P chloride
MNLFNLIM_00223 1.1e-145 lmrP E Major Facilitator Superfamily
MNLFNLIM_00224 5.4e-169 T PhoQ Sensor
MNLFNLIM_00225 7.2e-103 K response regulator
MNLFNLIM_00226 1.4e-131 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MNLFNLIM_00227 9.5e-234 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MNLFNLIM_00228 2.3e-128 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MNLFNLIM_00229 1.1e-207 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MNLFNLIM_00230 6.1e-180 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MNLFNLIM_00231 2.7e-135 cggR K Putative sugar-binding domain
MNLFNLIM_00233 1.1e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MNLFNLIM_00234 1.8e-149 whiA K May be required for sporulation
MNLFNLIM_00235 6.3e-153 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MNLFNLIM_00236 7.5e-126 rapZ S Displays ATPase and GTPase activities
MNLFNLIM_00237 1.3e-79 ylbE GM NAD dependent epimerase dehydratase family protein
MNLFNLIM_00238 1.1e-83 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MNLFNLIM_00239 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MNLFNLIM_00240 2.5e-83 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MNLFNLIM_00241 3.4e-07 fhaB M translation initiation factor activity
MNLFNLIM_00242 1.5e-42 K Copper transport repressor CopY TcrY
MNLFNLIM_00243 1.2e-45 T Belongs to the universal stress protein A family
MNLFNLIM_00244 3.8e-40 K Bacterial regulatory proteins, tetR family
MNLFNLIM_00245 1.8e-31 K transcriptional
MNLFNLIM_00246 2.4e-71 mleR K LysR family
MNLFNLIM_00247 5.8e-249 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
MNLFNLIM_00248 1.6e-13 mleP S Sodium Bile acid symporter family
MNLFNLIM_00249 1.6e-63 S ECF transporter, substrate-specific component
MNLFNLIM_00250 1.6e-61 acmC 3.2.1.96 NU mannosyl-glycoprotein
MNLFNLIM_00251 9.7e-74 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MNLFNLIM_00252 1.7e-193 pbuX F xanthine permease
MNLFNLIM_00253 3e-37 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
MNLFNLIM_00254 9e-255 topB 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MNLFNLIM_00255 2.5e-94 yjbM 2.7.6.5 S RelA SpoT domain protein
MNLFNLIM_00256 7.6e-117 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MNLFNLIM_00257 7.6e-94 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
MNLFNLIM_00258 3.2e-160 mgtE P Acts as a magnesium transporter
MNLFNLIM_00260 1.7e-40
MNLFNLIM_00261 2.2e-34 K Acetyltransferase (GNAT) domain
MNLFNLIM_00262 3.8e-209 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
MNLFNLIM_00263 4.6e-220 gdhA 1.4.1.4 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
MNLFNLIM_00264 2.2e-42 O ADP-ribosylglycohydrolase
MNLFNLIM_00265 2.1e-220 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
MNLFNLIM_00266 6.2e-266 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MNLFNLIM_00267 4e-156 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MNLFNLIM_00268 3.1e-119 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
MNLFNLIM_00269 4.7e-194 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
MNLFNLIM_00270 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MNLFNLIM_00271 1.5e-176 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
MNLFNLIM_00272 3.4e-24 S Domain of unknown function (DUF4828)
MNLFNLIM_00273 5.4e-128 mocA S Oxidoreductase
MNLFNLIM_00274 3.9e-160 yfmL L DEAD DEAH box helicase
MNLFNLIM_00275 2e-20 S Domain of unknown function (DUF3284)
MNLFNLIM_00277 3e-279 kup P Transport of potassium into the cell
MNLFNLIM_00278 1.2e-100 malR K Transcriptional regulator, LacI family
MNLFNLIM_00279 3.8e-214 malT G Transporter, major facilitator family protein
MNLFNLIM_00280 7.7e-79 galM 5.1.3.3 G Aldose 1-epimerase
MNLFNLIM_00281 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
MNLFNLIM_00282 4.1e-84 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
MNLFNLIM_00283 2.2e-264 E Amino acid permease
MNLFNLIM_00284 1.3e-181 pepS E Thermophilic metalloprotease (M29)
MNLFNLIM_00285 2.1e-168 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MNLFNLIM_00286 1.1e-70 K Sugar-specific transcriptional regulator TrmB
MNLFNLIM_00287 6.4e-122 S Sulfite exporter TauE/SafE
MNLFNLIM_00288 5.2e-120 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
MNLFNLIM_00289 0.0 S Bacterial membrane protein YfhO
MNLFNLIM_00290 8.7e-53 gtcA S Teichoic acid glycosylation protein
MNLFNLIM_00291 5.1e-54 fld C Flavodoxin
MNLFNLIM_00292 7.8e-136 S interspecies interaction between organisms
MNLFNLIM_00293 1.2e-207 G glycerol-3-phosphate transporter
MNLFNLIM_00294 5.8e-72 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MNLFNLIM_00295 4.8e-145 htrA 3.4.21.107 O serine protease
MNLFNLIM_00296 2.2e-116 vicX 3.1.26.11 S domain protein
MNLFNLIM_00297 1e-15 yjbR S protein conserved in bacteria
MNLFNLIM_00299 5.6e-80 yycI S YycH protein
MNLFNLIM_00300 7.9e-103 yycH S YycH protein
MNLFNLIM_00301 1.5e-272 vicK 2.7.13.3 T Histidine kinase
MNLFNLIM_00302 9e-114 K response regulator
MNLFNLIM_00303 6.1e-106 yxeH S hydrolase
MNLFNLIM_00304 3.8e-227 V ABC transporter transmembrane region
MNLFNLIM_00305 1.1e-216 XK27_09600 V ABC transporter, ATP-binding protein
MNLFNLIM_00306 7.1e-32 K Transcriptional regulator, MarR family
MNLFNLIM_00307 8.9e-174 S Putative peptidoglycan binding domain
MNLFNLIM_00308 3.8e-62 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MNLFNLIM_00309 3.6e-138 gldA 1.1.1.6 C Iron-containing alcohol dehydrogenase
MNLFNLIM_00310 1.5e-179 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MNLFNLIM_00311 3.1e-106 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MNLFNLIM_00312 4.2e-224 pepF E Oligopeptidase F
MNLFNLIM_00313 3.7e-96 yicL EG EamA-like transporter family
MNLFNLIM_00314 7e-69 2.3.1.178 J Acetyltransferase (GNAT) domain
MNLFNLIM_00315 1e-166 yjjP S Putative threonine/serine exporter
MNLFNLIM_00316 2.9e-24 S PFAM Archaeal ATPase
MNLFNLIM_00317 2.2e-58 S PFAM Archaeal ATPase
MNLFNLIM_00318 2.7e-170 ydfJ EGP Sugar (and other) transporter
MNLFNLIM_00319 2.6e-138 rspB 1.1.1.380 C Zinc-binding dehydrogenase
MNLFNLIM_00320 1.5e-173 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
MNLFNLIM_00321 2.5e-207 mtlD 1.1.1.17, 1.1.1.57 G Mannitol dehydrogenase C-terminal domain
MNLFNLIM_00322 1.5e-49 kdgR K FCD domain
MNLFNLIM_00323 1e-113 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
MNLFNLIM_00324 3.3e-62 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
MNLFNLIM_00325 4.8e-109 glcU U sugar transport
MNLFNLIM_00326 1e-14 yobS K transcriptional regulator
MNLFNLIM_00327 2e-153 mdtG EGP Major facilitator Superfamily
MNLFNLIM_00328 1.2e-105 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
MNLFNLIM_00329 4.2e-223 yxbA 6.3.1.12 S ATP-grasp enzyme
MNLFNLIM_00330 2.8e-229 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MNLFNLIM_00331 9.5e-18 yneR
MNLFNLIM_00332 2.8e-247 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MNLFNLIM_00333 1.6e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MNLFNLIM_00334 5.1e-59 yiiE S Protein of unknown function (DUF1211)
MNLFNLIM_00335 0.0 asnB 6.3.5.4 E Asparagine synthase
MNLFNLIM_00336 7.4e-64 D peptidase
MNLFNLIM_00337 7.3e-117 S Glycosyl transferase family 2
MNLFNLIM_00338 2.4e-108 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
MNLFNLIM_00339 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MNLFNLIM_00340 3.3e-63 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MNLFNLIM_00341 4.8e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
MNLFNLIM_00342 2.6e-256 uup S ABC transporter, ATP-binding protein
MNLFNLIM_00343 9.2e-160 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MNLFNLIM_00344 1.1e-28 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
MNLFNLIM_00345 8.2e-70 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
MNLFNLIM_00346 1.2e-140 ansA 3.5.1.1 EJ Asparaginase
MNLFNLIM_00347 7.2e-82 fat 3.1.2.21 I Acyl-ACP thioesterase
MNLFNLIM_00348 2.1e-96 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MNLFNLIM_00349 1.4e-40 yabA L Involved in initiation control of chromosome replication
MNLFNLIM_00350 3e-83 holB 2.7.7.7 L DNA polymerase III
MNLFNLIM_00351 8.1e-66 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MNLFNLIM_00352 7.1e-29 yaaL S Protein of unknown function (DUF2508)
MNLFNLIM_00353 2.2e-97 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MNLFNLIM_00354 7e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MNLFNLIM_00355 4.6e-212 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MNLFNLIM_00356 3.3e-62 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MNLFNLIM_00357 6.4e-76 rsmC 2.1.1.172 J Methyltransferase
MNLFNLIM_00358 1.2e-27 nrdH O Glutaredoxin
MNLFNLIM_00359 4.8e-45 nrdI F NrdI Flavodoxin like
MNLFNLIM_00360 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MNLFNLIM_00361 3.9e-160 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MNLFNLIM_00362 2.7e-301 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MNLFNLIM_00363 1.1e-54
MNLFNLIM_00364 2.6e-48 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MNLFNLIM_00365 1.7e-74 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MNLFNLIM_00366 1.6e-115 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MNLFNLIM_00367 5e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MNLFNLIM_00368 7.7e-84 nusG K Participates in transcription elongation, termination and antitermination
MNLFNLIM_00369 2.6e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MNLFNLIM_00370 3.1e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MNLFNLIM_00371 7.8e-64 yacP S YacP-like NYN domain
MNLFNLIM_00372 1.2e-108 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MNLFNLIM_00373 3.8e-56 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MNLFNLIM_00374 1.1e-206 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MNLFNLIM_00375 3.2e-246 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MNLFNLIM_00376 8.2e-154 yacL S domain protein
MNLFNLIM_00377 3.5e-223 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MNLFNLIM_00378 4e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
MNLFNLIM_00379 8.1e-18 HA62_12640 S GCN5-related N-acetyl-transferase
MNLFNLIM_00380 5.8e-223 pepC 3.4.22.40 E Peptidase C1-like family
MNLFNLIM_00381 1e-33 S Enterocin A Immunity
MNLFNLIM_00382 2.9e-85 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MNLFNLIM_00383 1e-128 mleP2 S Sodium Bile acid symporter family
MNLFNLIM_00384 3.5e-116 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MNLFNLIM_00386 1.5e-42 ydcK S Belongs to the SprT family
MNLFNLIM_00387 1.1e-250 yhgF K Tex-like protein N-terminal domain protein
MNLFNLIM_00388 1.8e-129 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MNLFNLIM_00389 9.5e-243 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MNLFNLIM_00390 1.4e-90 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MNLFNLIM_00391 4.9e-96 gntR1 K UbiC transcription regulator-associated domain protein
MNLFNLIM_00392 1e-89 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MNLFNLIM_00394 1.1e-07
MNLFNLIM_00395 1.6e-197 dtpT U amino acid peptide transporter
MNLFNLIM_00398 5.9e-94 L PLD-like domain
MNLFNLIM_00400 3.1e-09 tcdC
MNLFNLIM_00402 3.1e-233 tetP J elongation factor G
MNLFNLIM_00403 1.6e-31 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MNLFNLIM_00405 6.9e-217 yjeM E Amino Acid
MNLFNLIM_00406 1.5e-56 yphA GM NAD dependent epimerase/dehydratase family
MNLFNLIM_00407 4.3e-75 K Helix-turn-helix domain, rpiR family
MNLFNLIM_00408 2.5e-92 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MNLFNLIM_00409 1.3e-127 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
MNLFNLIM_00410 6.5e-90 nanK GK ROK family
MNLFNLIM_00411 1.1e-53 ndk 2.7.4.6 F Belongs to the NDK family
MNLFNLIM_00412 4e-64 G Xylose isomerase domain protein TIM barrel
MNLFNLIM_00413 5.6e-153 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MNLFNLIM_00414 7.8e-208 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MNLFNLIM_00415 1.1e-73 sdaAB 4.3.1.17 E Serine dehydratase beta chain
MNLFNLIM_00416 4.7e-112 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MNLFNLIM_00417 7.7e-41 S Iron-sulfur cluster assembly protein
MNLFNLIM_00418 1.3e-66 S Protein of unknown function (DUF1440)
MNLFNLIM_00419 1.7e-81 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
MNLFNLIM_00420 5.9e-187 mtnE 2.6.1.83 E Aminotransferase
MNLFNLIM_00422 2.7e-15
MNLFNLIM_00423 1e-87 S Haloacid dehalogenase-like hydrolase
MNLFNLIM_00426 2.9e-71 xerD L Phage integrase, N-terminal SAM-like domain
MNLFNLIM_00427 6.3e-266 fbp 3.1.3.11 G phosphatase activity
MNLFNLIM_00429 9.2e-32 tonB M YSIRK type signal peptide
MNLFNLIM_00432 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MNLFNLIM_00433 3e-98 fabK 1.3.1.9 S Nitronate monooxygenase
MNLFNLIM_00434 1.1e-21 S Phage minor capsid protein 2
MNLFNLIM_00442 1.7e-52 M Phage tail tape measure protein TP901
MNLFNLIM_00443 1e-26 M by MetaGeneAnnotator
MNLFNLIM_00444 5.2e-110 IQ NAD dependent epimerase/dehydratase family
MNLFNLIM_00445 1.7e-103 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
MNLFNLIM_00446 4.5e-43 gutM K Glucitol operon activator protein (GutM)
MNLFNLIM_00447 4.8e-83 srlA G PTS system enzyme II sorbitol-specific factor
MNLFNLIM_00448 6e-135 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
MNLFNLIM_00449 2.4e-36 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
MNLFNLIM_00450 4.8e-190 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MNLFNLIM_00451 9.4e-243 lysP E amino acid
MNLFNLIM_00452 6.8e-69 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
MNLFNLIM_00453 7.3e-271 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MNLFNLIM_00454 3.2e-14 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MNLFNLIM_00455 9.4e-57 lssY 3.6.1.27 I phosphatidate phosphatase activity
MNLFNLIM_00456 4.5e-83 lysR5 K LysR substrate binding domain
MNLFNLIM_00457 1.7e-119 yxaA S membrane transporter protein
MNLFNLIM_00458 2.6e-32 ywjH S Protein of unknown function (DUF1634)
MNLFNLIM_00459 4.3e-123 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MNLFNLIM_00460 1.7e-225 pipD E Dipeptidase
MNLFNLIM_00461 7.5e-20 K helix_turn_helix multiple antibiotic resistance protein
MNLFNLIM_00462 1.3e-164 EGP Major facilitator Superfamily
MNLFNLIM_00463 5.6e-82 S L,D-transpeptidase catalytic domain
MNLFNLIM_00464 7.8e-141 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MNLFNLIM_00465 7.4e-144 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MNLFNLIM_00466 7.2e-27 ydiI Q Thioesterase superfamily
MNLFNLIM_00467 4.7e-56 yfeJ 6.3.5.2 F glutamine amidotransferase
MNLFNLIM_00468 9.6e-148 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
MNLFNLIM_00469 1.9e-113 degV S EDD domain protein, DegV family
MNLFNLIM_00470 3.7e-135 cadA P P-type ATPase
MNLFNLIM_00471 3.1e-88 cadA P P-type ATPase
MNLFNLIM_00472 2.9e-249 E Amino acid permease
MNLFNLIM_00473 6e-83 S Membrane
MNLFNLIM_00474 2e-49 cps3F
MNLFNLIM_00475 2.3e-300 fruA 2.7.1.202 GT Phosphotransferase System
MNLFNLIM_00476 4.5e-150 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MNLFNLIM_00477 2.2e-86 fruR K DeoR C terminal sensor domain
MNLFNLIM_00478 8.8e-219 XK27_08635 S UPF0210 protein
MNLFNLIM_00479 4.1e-27 gcvR T Belongs to the UPF0237 family
MNLFNLIM_00480 6.1e-39
MNLFNLIM_00481 1.4e-76 E GDSL-like Lipase/Acylhydrolase family
MNLFNLIM_00482 9.2e-56 S Protein of unknown function (DUF975)
MNLFNLIM_00483 1.2e-148 lplA 6.3.1.20 H Lipoate-protein ligase
MNLFNLIM_00484 1.5e-229 lpdA 1.8.1.4 C Dehydrogenase
MNLFNLIM_00485 9e-181 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MNLFNLIM_00486 5.7e-167 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
MNLFNLIM_00487 4.7e-178 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
MNLFNLIM_00488 7.9e-07 M Cell surface protein
MNLFNLIM_00489 9.1e-170 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
MNLFNLIM_00490 1.2e-47 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MNLFNLIM_00491 6.6e-69 coiA 3.6.4.12 S Competence protein
MNLFNLIM_00492 1.2e-229 pepF E oligoendopeptidase F
MNLFNLIM_00493 2.3e-41 yjbH Q Thioredoxin
MNLFNLIM_00494 1.9e-97 pstS P Phosphate
MNLFNLIM_00495 1.6e-118 pstC P probably responsible for the translocation of the substrate across the membrane
MNLFNLIM_00496 3.9e-122 pstA P Phosphate transport system permease protein PstA
MNLFNLIM_00497 2.7e-114 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MNLFNLIM_00498 4.7e-116 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MNLFNLIM_00499 3.6e-56 P Plays a role in the regulation of phosphate uptake
MNLFNLIM_00500 1.8e-148 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
MNLFNLIM_00501 1.1e-79 S VIT family
MNLFNLIM_00502 9.4e-84 S membrane
MNLFNLIM_00503 1.2e-17 M1-874 K Domain of unknown function (DUF1836)
MNLFNLIM_00504 1.8e-65 hly S protein, hemolysin III
MNLFNLIM_00505 7.1e-35 K helix_turn_helix, Arsenical Resistance Operon Repressor
MNLFNLIM_00506 1.3e-74 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MNLFNLIM_00509 5.1e-14
MNLFNLIM_00510 1.3e-172 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MNLFNLIM_00511 1.3e-158 ccpA K catabolite control protein A
MNLFNLIM_00512 1.1e-41 S VanZ like family
MNLFNLIM_00513 1.5e-119 yebC K Transcriptional regulatory protein
MNLFNLIM_00514 2.3e-101 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MNLFNLIM_00515 1.1e-120 comGA NU Type II IV secretion system protein
MNLFNLIM_00516 1.8e-85 comGB NU type II secretion system
MNLFNLIM_00517 1.8e-26 comGC U competence protein ComGC
MNLFNLIM_00518 5e-14
MNLFNLIM_00520 1.6e-10 S Putative Competence protein ComGF
MNLFNLIM_00522 5.8e-98 ytxK 2.1.1.72 L N-6 DNA Methylase
MNLFNLIM_00523 1.7e-182 cycA E Amino acid permease
MNLFNLIM_00524 3e-57 S Calcineurin-like phosphoesterase
MNLFNLIM_00525 1.9e-53 yutD S Protein of unknown function (DUF1027)
MNLFNLIM_00526 2.9e-113 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MNLFNLIM_00527 4.6e-32 S Protein of unknown function (DUF1461)
MNLFNLIM_00528 3e-92 dedA S SNARE associated Golgi protein
MNLFNLIM_00529 2.3e-94 trxB2 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
MNLFNLIM_00530 1.1e-49 yugI 5.3.1.9 J general stress protein
MNLFNLIM_00531 2.3e-147 scrR K helix_turn _helix lactose operon repressor
MNLFNLIM_00532 1.2e-216 scrB 3.2.1.26 GH32 G invertase
MNLFNLIM_00533 5.2e-281 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
MNLFNLIM_00534 7.7e-183 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
MNLFNLIM_00535 1.6e-114 ntpJ P Potassium uptake protein
MNLFNLIM_00536 9.7e-59 ktrA P TrkA-N domain
MNLFNLIM_00537 1.7e-53 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
MNLFNLIM_00538 4e-38 M Glycosyltransferase like family 2
MNLFNLIM_00539 1.4e-19
MNLFNLIM_00540 2.3e-62 S Predicted membrane protein (DUF2207)
MNLFNLIM_00541 1.2e-19 S Predicted membrane protein (DUF2207)
MNLFNLIM_00542 3.3e-52 bioY S BioY family
MNLFNLIM_00543 2.8e-281 fruA 3.2.1.1, 3.2.1.65, 3.2.1.80 GH13,GH32 GN Fructan beta-fructosidase
MNLFNLIM_00544 1.1e-182 lmrB EGP Major facilitator Superfamily
MNLFNLIM_00545 2.4e-93 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MNLFNLIM_00546 8.4e-73 glcR K DeoR C terminal sensor domain
MNLFNLIM_00547 5e-60 yceE S haloacid dehalogenase-like hydrolase
MNLFNLIM_00548 6.9e-83 G Phosphoglycerate mutase family
MNLFNLIM_00549 1.3e-32 S Domain of unknown function (DUF4811)
MNLFNLIM_00550 2.7e-197 lmrB EGP Major facilitator Superfamily
MNLFNLIM_00551 4.2e-32 merR K MerR HTH family regulatory protein
MNLFNLIM_00552 2.3e-39 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MNLFNLIM_00553 5.3e-120 G Bacterial extracellular solute-binding protein
MNLFNLIM_00554 3e-79 baeR K Bacterial regulatory proteins, luxR family
MNLFNLIM_00555 1.2e-103 baeS T Histidine kinase
MNLFNLIM_00556 2.6e-79 rbsB G sugar-binding domain protein
MNLFNLIM_00557 5.3e-152 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
MNLFNLIM_00558 6.4e-116 manY G PTS system sorbose-specific iic component
MNLFNLIM_00559 3.9e-143 manN G system, mannose fructose sorbose family IID component
MNLFNLIM_00560 3.2e-52 manO S Domain of unknown function (DUF956)
MNLFNLIM_00561 4.2e-95 ypuA S Protein of unknown function (DUF1002)
MNLFNLIM_00562 1.5e-61 dedA 3.1.3.1 S SNARE associated Golgi protein
MNLFNLIM_00563 1.4e-159 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MNLFNLIM_00564 4.4e-18 yncA 2.3.1.79 S Maltose acetyltransferase
MNLFNLIM_00565 1.1e-206 yflS P Sodium:sulfate symporter transmembrane region
MNLFNLIM_00566 1.4e-198 frdC 1.3.5.4 C FAD binding domain
MNLFNLIM_00567 1.3e-236 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MNLFNLIM_00568 1.5e-14 ybaN S Protein of unknown function (DUF454)
MNLFNLIM_00569 1.1e-176 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
MNLFNLIM_00570 1.5e-57 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MNLFNLIM_00571 1.6e-96 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MNLFNLIM_00572 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
MNLFNLIM_00573 1.1e-71 ywlG S Belongs to the UPF0340 family
MNLFNLIM_00574 2.8e-157 C Oxidoreductase
MNLFNLIM_00575 2.5e-175 spoVK O PFAM ATPase family associated with various cellular activities (AAA)
MNLFNLIM_00576 8.1e-228 yfjM S Protein of unknown function DUF262
MNLFNLIM_00577 9e-75 S Domain of unknown function (DUF3841)
MNLFNLIM_00578 1.5e-57 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
MNLFNLIM_00579 8.4e-75 S Domain of unknown function (DUF4343)
MNLFNLIM_00580 5.7e-09
MNLFNLIM_00581 1.6e-14
MNLFNLIM_00582 1.9e-121 L Mrr N-terminal domain
MNLFNLIM_00583 2.6e-56 S UPF0489 domain
MNLFNLIM_00585 4.4e-34 3.1.21.3 V Type I restriction modification DNA specificity domain
MNLFNLIM_00586 5.1e-24
MNLFNLIM_00587 1.3e-11 arpU S Phage transcriptional regulator, ArpU family
MNLFNLIM_00589 2.8e-53
MNLFNLIM_00590 1.1e-165 S Terminase RNAseH like domain
MNLFNLIM_00591 3.4e-142 S Phage portal protein, SPP1 Gp6-like
MNLFNLIM_00592 9.6e-94 S Phage minor capsid protein 2
MNLFNLIM_00596 3.5e-20 S Phage minor structural protein GP20
MNLFNLIM_00597 4.3e-97 S T=7 icosahedral viral capsid
MNLFNLIM_00598 8.9e-15
MNLFNLIM_00599 9.7e-29 S Minor capsid protein
MNLFNLIM_00600 7.9e-16 S Minor capsid protein
MNLFNLIM_00601 7.6e-17 S Minor capsid protein from bacteriophage
MNLFNLIM_00602 3.4e-38 N domain, Protein
MNLFNLIM_00604 2.4e-38 S Bacteriophage Gp15 protein
MNLFNLIM_00605 2.2e-106 M Phage tail tape measure protein TP901
MNLFNLIM_00606 8.7e-60 S Phage tail protein
MNLFNLIM_00607 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MNLFNLIM_00608 1.2e-152 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MNLFNLIM_00609 9e-20 yaaA S S4 domain protein YaaA
MNLFNLIM_00610 8.6e-159 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MNLFNLIM_00611 2.1e-204 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MNLFNLIM_00612 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
MNLFNLIM_00613 2.2e-49 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MNLFNLIM_00614 3.1e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MNLFNLIM_00615 1.1e-199 nupG F Nucleoside
MNLFNLIM_00616 1.3e-121 MA20_14895 S Conserved hypothetical protein 698
MNLFNLIM_00617 1.9e-52 K LysR substrate binding domain
MNLFNLIM_00618 9.6e-09
MNLFNLIM_00619 3.2e-67 yxkH G Polysaccharide deacetylase
MNLFNLIM_00620 9e-30 yqkB S Belongs to the HesB IscA family
MNLFNLIM_00625 7.4e-177 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MNLFNLIM_00626 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MNLFNLIM_00627 2.4e-192 cycA E Amino acid permease
MNLFNLIM_00628 6.4e-187 ytgP S Polysaccharide biosynthesis protein
MNLFNLIM_00629 4e-61 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MNLFNLIM_00630 3.5e-80 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MNLFNLIM_00631 3e-193 pepV 3.5.1.18 E dipeptidase PepV
MNLFNLIM_00633 5.2e-36
MNLFNLIM_00634 3.4e-66 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MNLFNLIM_00635 4.2e-61 marR K Transcriptional regulator, MarR family
MNLFNLIM_00636 2.9e-102 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MNLFNLIM_00637 2.2e-27 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MNLFNLIM_00638 2.9e-104 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
MNLFNLIM_00639 1.1e-98 IQ reductase
MNLFNLIM_00640 2.1e-195 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MNLFNLIM_00641 4.6e-47 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MNLFNLIM_00642 3.9e-64 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MNLFNLIM_00643 9.3e-216 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
MNLFNLIM_00644 2.7e-125 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MNLFNLIM_00645 4.4e-101 accA 2.1.3.15, 6.4.1.2 I alpha subunit
MNLFNLIM_00646 5.5e-109 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
MNLFNLIM_00647 5.1e-231 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MNLFNLIM_00648 3.1e-240 pgi 5.3.1.9 G Belongs to the GPI family
MNLFNLIM_00649 1.8e-301 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MNLFNLIM_00650 5.7e-119 gla U Major intrinsic protein
MNLFNLIM_00651 5.8e-45 ykuL S CBS domain
MNLFNLIM_00652 3.9e-61 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MNLFNLIM_00653 5.4e-177 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MNLFNLIM_00654 1.5e-86 ykuT M mechanosensitive ion channel
MNLFNLIM_00656 3e-285 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MNLFNLIM_00657 2e-21 yheA S Belongs to the UPF0342 family
MNLFNLIM_00658 8.6e-128 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
MNLFNLIM_00659 3.3e-113 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MNLFNLIM_00661 2.7e-52 hit FG histidine triad
MNLFNLIM_00662 1.3e-94 ecsA V ABC transporter, ATP-binding protein
MNLFNLIM_00663 6.4e-72 ecsB U ABC transporter
MNLFNLIM_00664 1.6e-98 ytmP 2.7.1.89 M Choline/ethanolamine kinase
MNLFNLIM_00665 3.9e-100 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MNLFNLIM_00667 4e-45 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MNLFNLIM_00668 4e-76 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MNLFNLIM_00669 1.2e-239 sftA D Belongs to the FtsK SpoIIIE SftA family
MNLFNLIM_00670 7.6e-223 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MNLFNLIM_00671 2.5e-61 phaJ I N-terminal half of MaoC dehydratase
MNLFNLIM_00672 6.7e-69 ybhL S Belongs to the BI1 family
MNLFNLIM_00673 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MNLFNLIM_00674 4.3e-107 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MNLFNLIM_00675 1.6e-50 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MNLFNLIM_00676 6.1e-66 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MNLFNLIM_00677 4.7e-79 dnaB L replication initiation and membrane attachment
MNLFNLIM_00678 1.3e-107 dnaI L Primosomal protein DnaI
MNLFNLIM_00679 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MNLFNLIM_00680 1.3e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MNLFNLIM_00681 1.4e-24 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MNLFNLIM_00682 2.2e-52 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MNLFNLIM_00683 1.2e-70 yqeG S HAD phosphatase, family IIIA
MNLFNLIM_00684 6.7e-180 yqeH S Ribosome biogenesis GTPase YqeH
MNLFNLIM_00685 6e-30 yhbY J RNA-binding protein
MNLFNLIM_00686 3.5e-77 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MNLFNLIM_00687 2.6e-69 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
MNLFNLIM_00688 1.5e-48 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MNLFNLIM_00689 1.5e-82 H Nodulation protein S (NodS)
MNLFNLIM_00690 1.1e-121 ylbM S Belongs to the UPF0348 family
MNLFNLIM_00691 2e-57 yceD S Uncharacterized ACR, COG1399
MNLFNLIM_00692 1.9e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MNLFNLIM_00693 4e-89 plsC 2.3.1.51 I Acyltransferase
MNLFNLIM_00694 8.5e-94 yabB 2.1.1.223 L Methyltransferase small domain
MNLFNLIM_00695 1.5e-27 yazA L GIY-YIG catalytic domain protein
MNLFNLIM_00696 1.9e-128 rpsB J Belongs to the universal ribosomal protein uS2 family
MNLFNLIM_00697 1.4e-127 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MNLFNLIM_00698 6.9e-37
MNLFNLIM_00699 5.6e-54 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
MNLFNLIM_00700 2.6e-17 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
MNLFNLIM_00701 3.1e-57 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MNLFNLIM_00702 7.1e-158 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MNLFNLIM_00703 2.5e-184 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MNLFNLIM_00704 6.6e-107 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MNLFNLIM_00706 3.1e-111 K response regulator
MNLFNLIM_00707 3.9e-167 arlS 2.7.13.3 T Histidine kinase
MNLFNLIM_00708 5.1e-117 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MNLFNLIM_00709 1.6e-23 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MNLFNLIM_00710 4.7e-136 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
MNLFNLIM_00711 7.3e-105
MNLFNLIM_00712 5.5e-117
MNLFNLIM_00713 1.3e-41 dut S dUTPase
MNLFNLIM_00714 2.8e-94 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MNLFNLIM_00715 3.7e-46 yqhY S Asp23 family, cell envelope-related function
MNLFNLIM_00716 5.5e-36 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MNLFNLIM_00717 2.3e-103 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MNLFNLIM_00718 9.9e-146 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MNLFNLIM_00719 9.6e-17 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MNLFNLIM_00720 1.6e-83 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MNLFNLIM_00721 1.2e-120 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MNLFNLIM_00722 6.6e-49 argR K Regulates arginine biosynthesis genes
MNLFNLIM_00723 8.7e-176 recN L May be involved in recombinational repair of damaged DNA
MNLFNLIM_00724 2.5e-83 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MNLFNLIM_00725 2.2e-30 ynzC S UPF0291 protein
MNLFNLIM_00726 2.9e-26 yneF S UPF0154 protein
MNLFNLIM_00727 1.6e-92 engB D Necessary for normal cell division and for the maintenance of normal septation
MNLFNLIM_00728 2.1e-43 MA20_27270 S mazG nucleotide pyrophosphohydrolase
MNLFNLIM_00729 2.5e-75 yciQ P membrane protein (DUF2207)
MNLFNLIM_00730 1.3e-19 D nuclear chromosome segregation
MNLFNLIM_00731 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MNLFNLIM_00732 1.6e-38 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MNLFNLIM_00733 2.4e-68 gluP 3.4.21.105 S Peptidase, S54 family
MNLFNLIM_00734 1.5e-25 yqgQ S Bacterial protein of unknown function (DUF910)
MNLFNLIM_00735 6.2e-158 glk 2.7.1.2 G Glucokinase
MNLFNLIM_00736 2.7e-46 yqhL P Rhodanese-like protein
MNLFNLIM_00737 9.7e-17 WQ51_02665 S Protein of unknown function (DUF3042)
MNLFNLIM_00738 3.9e-109 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MNLFNLIM_00739 3.6e-206 ynbB 4.4.1.1 P aluminum resistance
MNLFNLIM_00740 1.3e-45 glnR K Transcriptional regulator
MNLFNLIM_00741 2e-247 glnA 6.3.1.2 E glutamine synthetase
MNLFNLIM_00743 4.4e-37 ogt 2.1.1.63 H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MNLFNLIM_00744 2.7e-48 S Domain of unknown function (DUF956)
MNLFNLIM_00745 8.3e-115 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MNLFNLIM_00746 2.5e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MNLFNLIM_00747 1.7e-105 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MNLFNLIM_00748 5.1e-102 cdsA 2.7.7.41 S Belongs to the CDS family
MNLFNLIM_00749 2e-156 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
MNLFNLIM_00750 1e-259 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MNLFNLIM_00751 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MNLFNLIM_00752 2.7e-66 rimP J Required for maturation of 30S ribosomal subunits
MNLFNLIM_00753 3.7e-170 nusA K Participates in both transcription termination and antitermination
MNLFNLIM_00754 1.2e-38 ylxR K Protein of unknown function (DUF448)
MNLFNLIM_00755 3.4e-25 ylxQ J ribosomal protein
MNLFNLIM_00756 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MNLFNLIM_00757 1.3e-55 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MNLFNLIM_00758 3.1e-119 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MNLFNLIM_00759 1.1e-95 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MNLFNLIM_00760 1.4e-131 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MNLFNLIM_00761 4.2e-56 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MNLFNLIM_00762 5.9e-274 dnaK O Heat shock 70 kDa protein
MNLFNLIM_00763 1.2e-160 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MNLFNLIM_00764 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MNLFNLIM_00766 4.6e-205 glnP P ABC transporter
MNLFNLIM_00767 2.6e-119 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MNLFNLIM_00768 1.5e-31
MNLFNLIM_00769 2e-111 ampC V Beta-lactamase
MNLFNLIM_00770 3.5e-110 cobQ S glutamine amidotransferase
MNLFNLIM_00771 3e-219 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
MNLFNLIM_00772 3.1e-80 tdk 2.7.1.21 F thymidine kinase
MNLFNLIM_00773 1.3e-177 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MNLFNLIM_00774 1.4e-89 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MNLFNLIM_00775 7.7e-135 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MNLFNLIM_00776 1.1e-99 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MNLFNLIM_00777 2.6e-97 atpB C it plays a direct role in the translocation of protons across the membrane
MNLFNLIM_00778 1.8e-15 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MNLFNLIM_00779 2.4e-39 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MNLFNLIM_00780 7e-58 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MNLFNLIM_00781 6.3e-266 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MNLFNLIM_00782 1.3e-141 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MNLFNLIM_00783 1.7e-236 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MNLFNLIM_00784 3e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MNLFNLIM_00785 4.1e-15 ywzB S Protein of unknown function (DUF1146)
MNLFNLIM_00786 1.8e-195 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MNLFNLIM_00787 1.3e-166 mbl D Cell shape determining protein MreB Mrl
MNLFNLIM_00788 9e-27 yidD S Could be involved in insertion of integral membrane proteins into the membrane
MNLFNLIM_00789 1.3e-13 S Protein of unknown function (DUF2969)
MNLFNLIM_00790 1e-186 rodA D Belongs to the SEDS family
MNLFNLIM_00791 3.5e-26 arsC 1.20.4.1 P Belongs to the ArsC family
MNLFNLIM_00792 1.9e-94 2.7.1.89 M Phosphotransferase enzyme family
MNLFNLIM_00793 1.1e-102 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MNLFNLIM_00794 2.5e-21 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MNLFNLIM_00795 7.5e-121 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MNLFNLIM_00796 1.9e-288 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MNLFNLIM_00797 1.5e-140 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MNLFNLIM_00798 2e-154 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MNLFNLIM_00799 1.8e-23 stp 3.1.3.16 T phosphatase
MNLFNLIM_00800 1.8e-46 stp 3.1.3.16 T phosphatase
MNLFNLIM_00801 1.8e-192 KLT serine threonine protein kinase
MNLFNLIM_00802 8.4e-109 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MNLFNLIM_00803 3.5e-59 thiN 2.7.6.2 H thiamine pyrophosphokinase
MNLFNLIM_00804 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MNLFNLIM_00805 4.5e-53 asp S Asp23 family, cell envelope-related function
MNLFNLIM_00806 3.3e-239 yloV S DAK2 domain fusion protein YloV
MNLFNLIM_00807 2.2e-245 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MNLFNLIM_00808 1.8e-139 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MNLFNLIM_00809 7e-26 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MNLFNLIM_00810 3.9e-101 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MNLFNLIM_00811 5.2e-210 smc D Required for chromosome condensation and partitioning
MNLFNLIM_00812 5.5e-146 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MNLFNLIM_00813 1.2e-39 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MNLFNLIM_00814 5e-204 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MNLFNLIM_00815 3.6e-42 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MNLFNLIM_00816 1.1e-26 ylqC S Belongs to the UPF0109 family
MNLFNLIM_00817 2.5e-57 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MNLFNLIM_00818 1.9e-114 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MNLFNLIM_00819 3.3e-61 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
MNLFNLIM_00820 3.7e-199 yfnA E amino acid
MNLFNLIM_00821 3e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MNLFNLIM_00822 1.8e-32 rpsT J Binds directly to 16S ribosomal RNA
MNLFNLIM_00823 5.6e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MNLFNLIM_00824 6.9e-116 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MNLFNLIM_00825 1.2e-265 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MNLFNLIM_00826 1.6e-22 S Tetratricopeptide repeat
MNLFNLIM_00827 8e-216 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MNLFNLIM_00828 6e-196 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MNLFNLIM_00829 1e-197 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MNLFNLIM_00830 9.5e-248 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MNLFNLIM_00831 2.5e-300 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MNLFNLIM_00832 5e-23 ykzG S Belongs to the UPF0356 family
MNLFNLIM_00833 5.5e-25
MNLFNLIM_00834 6.3e-86 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MNLFNLIM_00835 4.1e-31 1.1.1.27 C L-malate dehydrogenase activity
MNLFNLIM_00836 1.5e-24 yktA S Belongs to the UPF0223 family
MNLFNLIM_00837 2.2e-76 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
MNLFNLIM_00838 0.0 typA T GTP-binding protein TypA
MNLFNLIM_00839 1.6e-148 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
MNLFNLIM_00840 3.2e-115 manY G PTS system
MNLFNLIM_00841 4.7e-147 manN G system, mannose fructose sorbose family IID component
MNLFNLIM_00842 2.3e-101 ftsW D Belongs to the SEDS family
MNLFNLIM_00843 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MNLFNLIM_00844 1.1e-17 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
MNLFNLIM_00845 8e-73 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
MNLFNLIM_00846 4e-49 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MNLFNLIM_00847 2.4e-131 ylbL T Belongs to the peptidase S16 family
MNLFNLIM_00848 2.2e-96 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MNLFNLIM_00849 2.2e-30 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MNLFNLIM_00850 1.2e-102 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MNLFNLIM_00851 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MNLFNLIM_00852 2.1e-226 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MNLFNLIM_00853 5.3e-139 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MNLFNLIM_00854 5.2e-75 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MNLFNLIM_00855 1.4e-233 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MNLFNLIM_00856 6.4e-163 purD 6.3.4.13 F Belongs to the GARS family
MNLFNLIM_00857 5.6e-24 S Acyltransferase family
MNLFNLIM_00858 1.3e-93 sip L Phage integrase, N-terminal SAM-like domain
MNLFNLIM_00859 1.6e-29
MNLFNLIM_00860 4.8e-29 S Domain of unknown function (DUF4352)
MNLFNLIM_00861 1.1e-29 E Zn peptidase
MNLFNLIM_00862 1.6e-20 xre K Helix-turn-helix domain
MNLFNLIM_00864 2.6e-08 K Phage regulatory protein
MNLFNLIM_00865 7.5e-77 K Phage regulatory protein
MNLFNLIM_00866 1.8e-16 S Hypothetical protein (DUF2513)
MNLFNLIM_00867 8.6e-32 K Phage antirepressor protein KilAC domain
MNLFNLIM_00869 4.1e-07
MNLFNLIM_00873 1.8e-77 recT L RecT family
MNLFNLIM_00874 2.8e-87 S PDDEXK-like domain of unknown function (DUF3799)
MNLFNLIM_00877 3.6e-45 ybl78 L DnaD domain protein
MNLFNLIM_00878 3.2e-30 dnaC L IstB-like ATP binding protein
MNLFNLIM_00879 3.1e-26 S sequence-specific DNA binding
MNLFNLIM_00882 2.7e-25 rusA L Endodeoxyribonuclease RusA
MNLFNLIM_00883 5.7e-27 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
MNLFNLIM_00884 1.5e-61 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
MNLFNLIM_00896 2.5e-63 V HNH endonuclease
MNLFNLIM_00897 1.1e-130 3.6.1.13, 3.6.1.55 F NUDIX domain
MNLFNLIM_00898 4e-270 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MNLFNLIM_00899 2.7e-102 pncA Q Isochorismatase family
MNLFNLIM_00901 3e-99 K Bacterial regulatory proteins, tetR family
MNLFNLIM_00902 2.9e-289 norB EGP Major Facilitator
MNLFNLIM_00903 2.5e-38 S RelB antitoxin
MNLFNLIM_00904 5.7e-104
MNLFNLIM_00905 1.6e-100 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
MNLFNLIM_00906 2.6e-247 gshR 1.8.1.7 C Glutathione reductase
MNLFNLIM_00907 2.1e-177 proV E ABC transporter, ATP-binding protein
MNLFNLIM_00908 4.4e-262 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MNLFNLIM_00909 3.8e-146 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MNLFNLIM_00910 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MNLFNLIM_00911 1.1e-278 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MNLFNLIM_00912 3.5e-160 camS S sex pheromone
MNLFNLIM_00913 7.6e-38 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MNLFNLIM_00914 1.8e-233 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MNLFNLIM_00915 1.9e-256 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MNLFNLIM_00916 3.4e-146 yegS 2.7.1.107 G Lipid kinase
MNLFNLIM_00917 2.2e-209 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MNLFNLIM_00918 1.2e-52 L Resolvase, N terminal domain
MNLFNLIM_00919 2.1e-48 L COG COG1961 Site-specific recombinases, DNA invertase Pin homologs
MNLFNLIM_00925 1.9e-15
MNLFNLIM_00926 1.5e-44 S magnesium ion binding
MNLFNLIM_00927 3.2e-12 L Primase C terminal 2 (PriCT-2)
MNLFNLIM_00928 9.5e-305 L Primase C terminal 2 (PriCT-2)
MNLFNLIM_00929 1.2e-262 L Helicase C-terminal domain protein
MNLFNLIM_00930 5.8e-79
MNLFNLIM_00931 7.4e-39
MNLFNLIM_00932 1.9e-49
MNLFNLIM_00933 1.1e-102 S AAA domain
MNLFNLIM_00934 3.9e-163 D AAA domain
MNLFNLIM_00939 6.6e-19
MNLFNLIM_00940 1.1e-42 K addiction module antidote protein HigA
MNLFNLIM_00941 1.7e-39 E IrrE N-terminal-like domain
MNLFNLIM_00942 5.2e-92 J Domain of unknown function (DUF4041)
MNLFNLIM_00943 3.5e-64 J Domain of unknown function (DUF4041)
MNLFNLIM_00944 1.8e-81 sip L Belongs to the 'phage' integrase family
MNLFNLIM_00945 2.1e-81 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MNLFNLIM_00946 1.2e-94 yeaN P Major Facilitator Superfamily
MNLFNLIM_00947 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MNLFNLIM_00948 4.9e-164 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MNLFNLIM_00949 9.1e-68 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
MNLFNLIM_00950 1.3e-85 K response regulator
MNLFNLIM_00951 5.3e-86 phoR 2.7.13.3 T Histidine kinase
MNLFNLIM_00952 4.1e-08 KT PspC domain protein
MNLFNLIM_00953 3.5e-26 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
MNLFNLIM_00954 7.4e-132 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MNLFNLIM_00955 1.1e-112 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MNLFNLIM_00956 6.1e-273 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MNLFNLIM_00957 4.5e-53 K Transcriptional regulator C-terminal region
MNLFNLIM_00958 6.1e-44 thiT S Thiamine transporter protein (Thia_YuaJ)
MNLFNLIM_00959 2e-285 pepO 3.4.24.71 O Peptidase family M13
MNLFNLIM_00960 5e-111 dat 2.6.1.21 EH PFAM aminotransferase, class IV
MNLFNLIM_00961 2.1e-07 yvaZ S SdpI/YhfL protein family
MNLFNLIM_00962 6.6e-71 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
MNLFNLIM_00963 6.7e-47 hmpT S ECF-type riboflavin transporter, S component
MNLFNLIM_00964 9.7e-41 wecD K Acetyltransferase GNAT Family
MNLFNLIM_00966 1.3e-37 aguA_2 3.5.3.12 E Porphyromonas-type peptidyl-arginine deiminase
MNLFNLIM_00967 9e-62 XK27_06780 V ABC transporter permease
MNLFNLIM_00968 1.2e-179 XK27_06780 V ABC transporter permease
MNLFNLIM_00969 1.2e-94 XK27_06785 V ABC transporter, ATP-binding protein
MNLFNLIM_00970 3.2e-34 tetR K transcriptional regulator
MNLFNLIM_00971 9.4e-149 mepA V MATE efflux family protein
MNLFNLIM_00972 3.3e-150 lsa S ABC transporter
MNLFNLIM_00973 1.4e-83 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MNLFNLIM_00974 8e-110 puuD S peptidase C26
MNLFNLIM_00975 1.4e-200 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
MNLFNLIM_00976 1.1e-25
MNLFNLIM_00977 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
MNLFNLIM_00978 1.1e-59 uspA T Universal stress protein family
MNLFNLIM_00980 4.7e-210 glnP P ABC transporter
MNLFNLIM_00981 5.4e-168 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MNLFNLIM_00982 9.7e-99 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MNLFNLIM_00983 1.3e-31 S CAAX protease self-immunity
MNLFNLIM_00984 2.4e-33 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MNLFNLIM_00985 1.1e-271 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MNLFNLIM_00986 5.7e-269 aha1 P COG COG0474 Cation transport ATPase
MNLFNLIM_00987 4.9e-297 ydaO E amino acid
MNLFNLIM_00988 1.6e-157 tagO 2.7.8.33, 2.7.8.35 M transferase
MNLFNLIM_00989 1.9e-128 comFA L Helicase C-terminal domain protein
MNLFNLIM_00990 3e-50 comFC S Competence protein
MNLFNLIM_00991 1.2e-48 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
MNLFNLIM_00992 2.6e-55 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
MNLFNLIM_00993 4.9e-148 D CobQ CobB MinD ParA nucleotide binding domain protein
MNLFNLIM_00994 8.5e-35
MNLFNLIM_00995 1.4e-185 repA S Replication initiator protein A
MNLFNLIM_00996 4.9e-25
MNLFNLIM_00997 6.8e-137 S Fic/DOC family
MNLFNLIM_00998 4.3e-43 relB L Addiction module antitoxin, RelB DinJ family
MNLFNLIM_00999 8.3e-27
MNLFNLIM_01000 3.4e-126 S protein conserved in bacteria
MNLFNLIM_01001 4e-41
MNLFNLIM_01002 2.8e-23
MNLFNLIM_01003 0.0 L MobA MobL family protein
MNLFNLIM_01004 5.5e-21
MNLFNLIM_01005 8.2e-59 cvfB S S1 domain
MNLFNLIM_01006 9.6e-113 xerD D recombinase XerD
MNLFNLIM_01007 8.4e-294 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
MNLFNLIM_01008 1.8e-76 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MNLFNLIM_01009 3.4e-189 nhaC C Na H antiporter NhaC
MNLFNLIM_01010 6e-65 ypsA S Belongs to the UPF0398 family
MNLFNLIM_01011 1.2e-196 ade 3.5.4.2 F Adenine deaminase C-terminal domain
MNLFNLIM_01012 5.9e-81 rfbP M Bacterial sugar transferase
MNLFNLIM_01013 2.7e-144 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MNLFNLIM_01014 4.2e-101 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MNLFNLIM_01015 1.6e-164 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MNLFNLIM_01016 4e-129 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MNLFNLIM_01018 6.5e-64 rny D Peptidase family M23
MNLFNLIM_01019 4.2e-117 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
MNLFNLIM_01020 7.3e-136 pfoS S Phosphotransferase system, EIIC
MNLFNLIM_01021 1.6e-26 K Helix-turn-helix XRE-family like proteins
MNLFNLIM_01022 5.3e-24 S protein encoded in hypervariable junctions of pilus gene clusters
MNLFNLIM_01023 2.9e-224 E ABC transporter, substratebinding protein
MNLFNLIM_01024 1.4e-115 sufC O FeS assembly ATPase SufC
MNLFNLIM_01025 1.1e-143 sufD O FeS assembly protein SufD
MNLFNLIM_01026 1.1e-146 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MNLFNLIM_01027 4.9e-41 nifU C SUF system FeS assembly protein, NifU family
MNLFNLIM_01028 9.4e-240 sufB O assembly protein SufB
MNLFNLIM_01029 7.2e-45 S VIT family
MNLFNLIM_01030 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
MNLFNLIM_01031 1.5e-136 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MNLFNLIM_01032 4.7e-112 rssA S Phospholipase, patatin family
MNLFNLIM_01033 3.1e-15
MNLFNLIM_01035 2.8e-38
MNLFNLIM_01036 1.5e-57 S Region found in RelA / SpoT proteins
MNLFNLIM_01037 8.5e-70 S Protein of unknown function (DUF4065)
MNLFNLIM_01038 2.1e-87 S Fic/DOC family
MNLFNLIM_01039 2.2e-11 S sequence-specific DNA binding
MNLFNLIM_01040 1.7e-11 3.4.21.88 K Peptidase S24-like
MNLFNLIM_01045 1.4e-09 S Arc-like DNA binding domain
MNLFNLIM_01047 1.3e-20 S Replication initiator protein A (RepA) N-terminus
MNLFNLIM_01052 1.1e-08
MNLFNLIM_01057 7.5e-20
MNLFNLIM_01058 1.9e-11 polC 2.7.7.7 L BRCA1 C Terminus (BRCT) domain
MNLFNLIM_01062 2.4e-63 ruvB 3.6.4.12 L four-way junction helicase activity
MNLFNLIM_01069 1.1e-77 S Fic/DOC family
MNLFNLIM_01070 3.4e-239 bcgIB 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
MNLFNLIM_01072 5.2e-67 D nuclear chromosome segregation
MNLFNLIM_01073 7.5e-08
MNLFNLIM_01074 1.2e-61 gepA K Protein of unknown function (DUF4065)
MNLFNLIM_01075 1.2e-28
MNLFNLIM_01076 2.4e-56 Z012_06740 S Fic/DOC family
MNLFNLIM_01077 5.9e-84 pspA D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MNLFNLIM_01078 2.6e-11 D Antitoxin component of a toxin-antitoxin (TA) module
MNLFNLIM_01079 3.5e-22 S PIN domain
MNLFNLIM_01081 3.2e-212 V N-6 DNA Methylase
MNLFNLIM_01082 6.6e-43 3.1.21.3 V type I restriction modification DNA specificity domain
MNLFNLIM_01084 4.5e-69
MNLFNLIM_01085 6.7e-51 L Psort location Cytoplasmic, score
MNLFNLIM_01086 7.2e-44 L Protein of unknown function (DUF3991)
MNLFNLIM_01087 7.1e-165 topA2 5.99.1.2 G Topoisomerase IA
MNLFNLIM_01090 1.9e-147 clpB O Belongs to the ClpA ClpB family
MNLFNLIM_01094 8.4e-219 U TraM recognition site of TraD and TraG
MNLFNLIM_01095 3.4e-77
MNLFNLIM_01097 8.7e-26
MNLFNLIM_01098 4.5e-192 U type IV secretory pathway VirB4
MNLFNLIM_01100 1.3e-30 M CHAP domain
MNLFNLIM_01103 6.5e-07
MNLFNLIM_01104 7.1e-23 sip L Belongs to the 'phage' integrase family
MNLFNLIM_01105 1.7e-14 sip L Belongs to the 'phage' integrase family
MNLFNLIM_01106 2.7e-30
MNLFNLIM_01107 1.7e-79 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MNLFNLIM_01108 1.2e-99 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MNLFNLIM_01109 6.8e-79 yvfR V ABC transporter
MNLFNLIM_01110 1.2e-52 yvfS V ABC-2 type transporter
MNLFNLIM_01111 3.2e-57 salK 2.7.13.3 T Histidine kinase
MNLFNLIM_01112 4.9e-76 desR K helix_turn_helix, Lux Regulon
MNLFNLIM_01113 8.7e-39 ptp3 3.1.3.48 T Tyrosine phosphatase family
MNLFNLIM_01114 8.2e-13 ptp3 3.1.3.48 T Tyrosine phosphatase family
MNLFNLIM_01115 3.4e-103 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
MNLFNLIM_01120 1.4e-32 S Domain of unknown function (DUF4417)
MNLFNLIM_01121 1.1e-142 xerS L Phage integrase family
MNLFNLIM_01122 2e-71 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MNLFNLIM_01123 6.5e-138 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MNLFNLIM_01124 1.6e-217 1.3.5.4 C FAD binding domain
MNLFNLIM_01125 5e-116 IQ Enoyl-(Acyl carrier protein) reductase
MNLFNLIM_01126 4.7e-138 G Xylose isomerase-like TIM barrel
MNLFNLIM_01127 3.7e-72 K Transcriptional regulator, LysR family
MNLFNLIM_01128 4.1e-98 EGP Major Facilitator Superfamily
MNLFNLIM_01129 2.6e-129 EGP Major Facilitator Superfamily
MNLFNLIM_01130 2.4e-35 L Integrase core domain
MNLFNLIM_01131 1.4e-41 L Integrase core domain
MNLFNLIM_01132 1.3e-20 L PFAM transposase IS3 IS911 family protein
MNLFNLIM_01133 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
MNLFNLIM_01134 1.7e-32 P Heavy-metal-associated domain
MNLFNLIM_01135 8.7e-31 tnp L Transposase IS66 family
MNLFNLIM_01136 5e-18 tnp
MNLFNLIM_01137 6.2e-43 L hmm pf00665
MNLFNLIM_01138 1.1e-124 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
MNLFNLIM_01139 4.6e-84 dps P Ferritin-like domain
MNLFNLIM_01140 1.1e-157 L transposase, IS605 OrfB family
MNLFNLIM_01141 2.5e-58 tlpA2 L Transposase IS200 like
MNLFNLIM_01142 4.1e-53 1.14.12.17 C Oxidoreductase NAD-binding domain
MNLFNLIM_01143 0.0 O Belongs to the peptidase S8 family
MNLFNLIM_01144 1e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MNLFNLIM_01146 7.9e-44 yjaB_1 K Acetyltransferase (GNAT) domain
MNLFNLIM_01147 4.5e-80 yitS S EDD domain protein, DegV family
MNLFNLIM_01148 1.1e-57 racA K Domain of unknown function (DUF1836)
MNLFNLIM_01149 3.6e-116 queH 1.17.99.6, 3.1.26.4 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MNLFNLIM_01150 3.3e-147 ald 1.4.1.1 C Belongs to the AlaDH PNT family
MNLFNLIM_01151 7.3e-168 potE2 E amino acid
MNLFNLIM_01155 2.3e-07 S zinc-finger-containing domain
MNLFNLIM_01156 2.7e-38 V HNH endonuclease
MNLFNLIM_01157 1.4e-156 spoVK O stage V sporulation protein K
MNLFNLIM_01161 5.5e-27
MNLFNLIM_01163 1.5e-14
MNLFNLIM_01164 1.5e-92 pstS P T5orf172
MNLFNLIM_01165 6.9e-257 yeeB L DEAD-like helicases superfamily
MNLFNLIM_01166 3.5e-89 yeeA V Type II restriction enzyme, methylase subunits
MNLFNLIM_01167 6.7e-215 yeeA V Type II restriction enzyme, methylase subunits
MNLFNLIM_01168 4.6e-66
MNLFNLIM_01169 4.4e-62
MNLFNLIM_01170 7.1e-161 L T/G mismatch-specific endonuclease activity
MNLFNLIM_01172 2.6e-56 hsdM 2.1.1.72 V type I restriction-modification system
MNLFNLIM_01173 1.1e-18 3.1.21.3 V Type I restriction modification DNA specificity domain
MNLFNLIM_01174 4e-106 L Belongs to the 'phage' integrase family
MNLFNLIM_01175 1.7e-19 S YjcQ protein
MNLFNLIM_01177 1.3e-108 rhaD 4.1.2.17, 4.1.2.19 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
MNLFNLIM_01178 2.2e-219 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
MNLFNLIM_01179 4e-40 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
MNLFNLIM_01180 3.7e-215 rhaB 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
MNLFNLIM_01181 1.5e-188 iolF EGP Major facilitator Superfamily
MNLFNLIM_01182 4.8e-76 rhaR K helix_turn_helix, arabinose operon control protein
MNLFNLIM_01183 4.2e-12 S Membrane
MNLFNLIM_01184 6.1e-181 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
MNLFNLIM_01185 1.5e-56 yvbG U MarC family integral membrane protein
MNLFNLIM_01186 4.2e-15 2.7.1.194, 2.7.1.202 GKT COG3711 Transcriptional antiterminator
MNLFNLIM_01187 1.2e-28 yedF O Belongs to the sulfur carrier protein TusA family
MNLFNLIM_01188 4.9e-149 yedE S Sulphur transport
MNLFNLIM_01189 7e-101 selD 2.7.9.3 E Synthesizes selenophosphate from selenide and ATP
MNLFNLIM_01190 2.4e-176 rnfC C RnfC Barrel sandwich hybrid domain
MNLFNLIM_01191 9e-29 yitW S Iron-sulfur cluster assembly protein
MNLFNLIM_01192 2.4e-110 selA 2.9.1.1 H Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis
MNLFNLIM_01193 1.1e-110 sufS 2.8.1.7, 4.4.1.16 E Serine hydroxymethyltransferase
MNLFNLIM_01194 1.4e-137 selB J Elongation factor SelB, winged helix
MNLFNLIM_01195 2.9e-07 S Protein of unknown function (DUF3343)
MNLFNLIM_01196 1.2e-48 yedF O Belongs to the sulfur carrier protein TusA family
MNLFNLIM_01197 7.7e-222 ybeC E amino acid
MNLFNLIM_01198 2.2e-93 XK27_00825 S Sulfite exporter TauE/SafE
MNLFNLIM_01199 1.7e-142 5.1.1.4 E Proline racemase
MNLFNLIM_01200 2.7e-66 3.5.1.1 EJ Glycine/sarcosine/betaine reductase component B subunits
MNLFNLIM_01201 8e-73 prdD S An automated process has identified a potential problem with this gene model
MNLFNLIM_01202 4.3e-31 S the current gene model (or a revised gene model) may contain a premature stop
MNLFNLIM_01203 4.5e-66 prdB 1.21.4.1, 1.21.4.2 S the current gene model (or a revised gene model) may contain a premature stop
MNLFNLIM_01204 7.1e-26 S Psort location Cytoplasmic, score
MNLFNLIM_01205 5.2e-178 prdA 1.21.4.1 EJ Glycine/sarcosine/betaine reductase component B subunits
MNLFNLIM_01206 3.7e-33 prdA 1.21.4.1 EJ Glycine/sarcosine/betaine reductase component B subunits
MNLFNLIM_01208 5e-116 ynjE 2.8.1.11 P Rhodanese Homology Domain
MNLFNLIM_01209 5.4e-17 yeeD O Belongs to the sulfur carrier protein TusA family
MNLFNLIM_01210 3.1e-62 yeeE S Sulphur transport
MNLFNLIM_01211 8.8e-105 yraQ S Predicted permease
MNLFNLIM_01212 1.4e-124 yvgN C Aldo keto reductase
MNLFNLIM_01216 3.4e-16
MNLFNLIM_01219 5.8e-21 M domain protein
MNLFNLIM_01220 1.7e-35 agrA KT Response regulator of the LytR AlgR family
MNLFNLIM_01221 6.7e-43 blpH 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
MNLFNLIM_01222 0.0 pepN 3.4.11.2 E aminopeptidase
MNLFNLIM_01223 4.8e-33
MNLFNLIM_01225 7.6e-125 D CobQ CobB MinD ParA nucleotide binding domain protein
MNLFNLIM_01226 6e-17 bglG K antiterminator
MNLFNLIM_01227 7.1e-90 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MNLFNLIM_01228 3.2e-171 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MNLFNLIM_01229 5.1e-38 S Replication initiator protein A (RepA) N-terminus
MNLFNLIM_01230 2.7e-108 L Initiator Replication protein
MNLFNLIM_01231 6.1e-08 yokH G regulation of fungal-type cell wall biogenesis
MNLFNLIM_01233 6.5e-12 L PLD-like domain
MNLFNLIM_01234 5.8e-09 E IrrE N-terminal-like domain
MNLFNLIM_01235 2.4e-32 K Helix-turn-helix XRE-family like proteins
MNLFNLIM_01236 1.1e-07 K Helix-turn-helix XRE-family like proteins
MNLFNLIM_01244 1.5e-45 L Bifunctional DNA primase/polymerase, N-terminal
MNLFNLIM_01245 9.8e-129 S D5 N terminal like
MNLFNLIM_01246 1.6e-75 xerC L Belongs to the 'phage' integrase family
MNLFNLIM_01247 3.6e-28 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MNLFNLIM_01248 8.4e-38 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MNLFNLIM_01249 2.5e-58 cpsF M Oligosaccharide biosynthesis protein Alg14 like
MNLFNLIM_01250 1.4e-43 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MNLFNLIM_01251 6.9e-92 M Core-2/I-Branching enzyme
MNLFNLIM_01252 1.3e-76 waaB GT4 M Glycosyl transferases group 1
MNLFNLIM_01253 3.2e-92 yihY S Belongs to the UPF0761 family
MNLFNLIM_01254 6.2e-12 mltD CBM50 M Lysin motif
MNLFNLIM_01255 1.2e-152 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MNLFNLIM_01258 5.7e-80 K SIR2-like domain
MNLFNLIM_01259 3.8e-22
MNLFNLIM_01260 7.3e-21 S Prophage endopeptidase tail
MNLFNLIM_01262 2.2e-137 L Transposase
MNLFNLIM_01263 1.1e-47 L Transposase
MNLFNLIM_01264 1.6e-261 3.1.11.5 L Psort location Cytoplasmic, score 8.87
MNLFNLIM_01265 1.4e-114 S N-acetylmuramoyl-L-alanine amidase activity
MNLFNLIM_01266 2.7e-21 S Bacteriophage holin of superfamily 6 (Holin_LLH)
MNLFNLIM_01269 1.7e-131 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MNLFNLIM_01270 7.2e-186 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MNLFNLIM_01271 1.7e-159 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MNLFNLIM_01272 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MNLFNLIM_01273 2.5e-119 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MNLFNLIM_01275 1.6e-55 ctsR K Belongs to the CtsR family
MNLFNLIM_01276 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MNLFNLIM_01277 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MNLFNLIM_01278 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MNLFNLIM_01279 1.9e-23 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
MNLFNLIM_01280 6.1e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MNLFNLIM_01281 1.3e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MNLFNLIM_01282 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MNLFNLIM_01283 9e-93 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MNLFNLIM_01284 6.8e-90 patB 4.4.1.8 E Aminotransferase, class I
MNLFNLIM_01285 1.4e-111 K response regulator
MNLFNLIM_01286 3.3e-142 hpk31 2.7.13.3 T Histidine kinase
MNLFNLIM_01287 2.1e-88 lacX 5.1.3.3 G Aldose 1-epimerase
MNLFNLIM_01288 1e-146 G Transporter, major facilitator family protein
MNLFNLIM_01289 1.7e-222 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MNLFNLIM_01290 3.1e-244 yhcA V ABC transporter, ATP-binding protein
MNLFNLIM_01291 1e-34 K Bacterial regulatory proteins, tetR family
MNLFNLIM_01292 3.4e-223 lmrA V ABC transporter, ATP-binding protein
MNLFNLIM_01293 3.3e-253 yfiC V ABC transporter
MNLFNLIM_01295 1.1e-45 yjcF K protein acetylation
MNLFNLIM_01296 1.1e-54 L phosphatase homologous to the C-terminal domain of histone macroH2A1
MNLFNLIM_01297 3e-72 lemA S LemA family
MNLFNLIM_01298 1.3e-114 htpX O Belongs to the peptidase M48B family
MNLFNLIM_01300 1.4e-269 helD 3.6.4.12 L DNA helicase
MNLFNLIM_01301 9.3e-128 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MNLFNLIM_01302 2.3e-171 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
MNLFNLIM_01303 5.5e-103 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
MNLFNLIM_01304 3.2e-82 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
MNLFNLIM_01305 2.4e-105 ybhR V ABC transporter
MNLFNLIM_01306 3.9e-31 K Transcriptional regulator
MNLFNLIM_01307 4.2e-43 VPA1512 ET Bacterial extracellular solute-binding proteins, family 3
MNLFNLIM_01308 1.8e-152 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
MNLFNLIM_01309 3.3e-127
MNLFNLIM_01310 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MNLFNLIM_01311 1.7e-102 tatD L hydrolase, TatD family
MNLFNLIM_01312 3.4e-87 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MNLFNLIM_01313 1.4e-132 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MNLFNLIM_01314 1.2e-22 veg S Biofilm formation stimulator VEG
MNLFNLIM_01315 5.6e-91 S Alpha/beta hydrolase of unknown function (DUF915)
MNLFNLIM_01316 1e-132 arcT 2.6.1.1 E Cys/Met metabolism PLP-dependent enzyme
MNLFNLIM_01317 6.6e-46 argR K Regulates arginine biosynthesis genes
MNLFNLIM_01318 3.7e-117 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MNLFNLIM_01319 1.8e-155 amtB P ammonium transporter
MNLFNLIM_01320 2.5e-89 sip L Belongs to the 'phage' integrase family
MNLFNLIM_01321 5.6e-31 S ParE toxin of type II toxin-antitoxin system, parDE
MNLFNLIM_01322 9.7e-23
MNLFNLIM_01324 4.8e-76
MNLFNLIM_01325 1e-09
MNLFNLIM_01329 5.7e-37 XK27_10050 K Peptidase S24-like
MNLFNLIM_01333 1.5e-16
MNLFNLIM_01335 1.2e-15 K Cro/C1-type HTH DNA-binding domain
MNLFNLIM_01336 1e-08 cro K Helix-turn-helix XRE-family like proteins
MNLFNLIM_01337 4.6e-81 S DNA binding
MNLFNLIM_01342 1.7e-54 S Putative HNHc nuclease
MNLFNLIM_01343 1.4e-27 S Phage replisome organizer, N-terminal domain protein
MNLFNLIM_01346 1.6e-25
MNLFNLIM_01347 2.2e-70
MNLFNLIM_01357 1.2e-34 arpU S Phage transcriptional regulator, ArpU family
MNLFNLIM_01359 1.7e-28 S Predicted membrane protein (DUF2335)
MNLFNLIM_01362 7.3e-84 L HNH nucleases
MNLFNLIM_01363 2.2e-76 L Phage terminase, small subunit
MNLFNLIM_01364 0.0 S Phage Terminase
MNLFNLIM_01366 5.7e-198 S Phage portal protein
MNLFNLIM_01367 1e-112 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
MNLFNLIM_01368 8.5e-197 S Phage capsid family
MNLFNLIM_01369 6.3e-22 S Phage gp6-like head-tail connector protein
MNLFNLIM_01370 3.3e-56 S Phage head-tail joining protein
MNLFNLIM_01371 4.2e-52 S Bacteriophage HK97-gp10, putative tail-component
MNLFNLIM_01372 3e-55 S Protein of unknown function (DUF806)
MNLFNLIM_01373 1.6e-78 S Phage tail tube protein
MNLFNLIM_01374 9.8e-17 S Phage tail assembly chaperone proteins, TAC
MNLFNLIM_01376 1.1e-306 M Phage tail tape measure protein TP901
MNLFNLIM_01377 4.6e-77 S Phage tail protein
MNLFNLIM_01378 6.8e-118 rny D peptidase
MNLFNLIM_01380 1.9e-27 S Calcineurin-like phosphoesterase
MNLFNLIM_01389 1.3e-105 M Glycosyl hydrolases family 25
MNLFNLIM_01390 1.3e-55 lys 3.5.1.104 M Glycosyl hydrolases family 25
MNLFNLIM_01391 2.2e-201 argH 4.3.2.1 E argininosuccinate lyase
MNLFNLIM_01392 1.7e-197 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MNLFNLIM_01393 3.4e-150 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
MNLFNLIM_01394 8.3e-108 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MNLFNLIM_01395 4.7e-103 pfoS S Phosphotransferase system, EIIC
MNLFNLIM_01396 2.2e-89 2.4.1.9 GH68 M MucBP domain
MNLFNLIM_01397 3.9e-185 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MNLFNLIM_01398 5.6e-52 adhR K helix_turn_helix, mercury resistance
MNLFNLIM_01399 5.2e-137 purR 2.4.2.7 F pur operon repressor
MNLFNLIM_01400 2.1e-46 EGP Transmembrane secretion effector
MNLFNLIM_01401 1.5e-192 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MNLFNLIM_01402 2.3e-168 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MNLFNLIM_01403 2.5e-20 rimL 1.1.1.25 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MNLFNLIM_01405 3.1e-113 dkg S reductase
MNLFNLIM_01406 9e-26
MNLFNLIM_01407 1.5e-77 2.4.2.3 F Phosphorylase superfamily
MNLFNLIM_01408 3.9e-290 ybiT S ABC transporter, ATP-binding protein
MNLFNLIM_01409 5.7e-62 bCE_4747 S Beta-lactamase superfamily domain
MNLFNLIM_01410 1.7e-99 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MNLFNLIM_01411 3e-124 S overlaps another CDS with the same product name
MNLFNLIM_01412 2.6e-87 S overlaps another CDS with the same product name
MNLFNLIM_01414 1.1e-55 spoVK O ATPase family associated with various cellular activities (AAA)
MNLFNLIM_01415 4.3e-12
MNLFNLIM_01417 4.1e-39 L COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
MNLFNLIM_01419 1.7e-71
MNLFNLIM_01420 3.7e-22
MNLFNLIM_01421 3.2e-103 ydcZ S Putative inner membrane exporter, YdcZ
MNLFNLIM_01422 4e-89 S hydrolase
MNLFNLIM_01423 9.5e-205 ywfO S HD domain protein
MNLFNLIM_01424 4.4e-86 yfeJ 6.3.5.2 F glutamine amidotransferase
MNLFNLIM_01425 9.1e-32 ywiB S Domain of unknown function (DUF1934)
MNLFNLIM_01426 9.9e-42 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MNLFNLIM_01427 3.1e-287 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MNLFNLIM_01430 4.6e-201 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MNLFNLIM_01431 3.1e-189 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MNLFNLIM_01432 3.6e-41 rpmE2 J Ribosomal protein L31
MNLFNLIM_01433 2.8e-61
MNLFNLIM_01434 2.6e-258 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
MNLFNLIM_01436 8e-79 S Cell surface protein
MNLFNLIM_01438 3.5e-180 pbuG S permease
MNLFNLIM_01439 4.9e-65 S Uncharacterized protein conserved in bacteria (DUF2263)
MNLFNLIM_01440 5.3e-179 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MNLFNLIM_01441 4.4e-208 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MNLFNLIM_01442 1e-29 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MNLFNLIM_01443 8.2e-146 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MNLFNLIM_01444 5.4e-13
MNLFNLIM_01445 2e-48 ndoA L Toxic component of a toxin-antitoxin (TA) module
MNLFNLIM_01446 1.5e-91 yunF F Protein of unknown function DUF72
MNLFNLIM_01447 6.6e-156 nrnB S DHHA1 domain
MNLFNLIM_01448 1.4e-42 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
MNLFNLIM_01449 3e-43
MNLFNLIM_01450 3.5e-09
MNLFNLIM_01451 7.3e-47 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain (presumed)
MNLFNLIM_01452 7e-23 S Cytochrome B5
MNLFNLIM_01453 1.8e-19 sigH K DNA-templated transcription, initiation
MNLFNLIM_01454 4.2e-67 recX 2.4.1.337 GT4 S Regulatory protein RecX
MNLFNLIM_01455 2.7e-191 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MNLFNLIM_01456 2.6e-97 ygaC J Belongs to the UPF0374 family
MNLFNLIM_01457 6.9e-92 yueF S AI-2E family transporter
MNLFNLIM_01458 6.5e-158 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MNLFNLIM_01459 1e-108 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MNLFNLIM_01460 7.5e-278 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MNLFNLIM_01461 0.0 lacL 3.2.1.23 G -beta-galactosidase
MNLFNLIM_01462 1.8e-206 lacS G Transporter
MNLFNLIM_01463 1.5e-58 lacS G Transporter
MNLFNLIM_01464 5.9e-111 galR K Transcriptional regulator
MNLFNLIM_01465 4.5e-179 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MNLFNLIM_01466 2.3e-163 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MNLFNLIM_01467 8.3e-202 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MNLFNLIM_01468 0.0 rafA 3.2.1.22 G alpha-galactosidase
MNLFNLIM_01469 1.1e-104 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
MNLFNLIM_01470 1.9e-22 XK27_09445 S Domain of unknown function (DUF1827)
MNLFNLIM_01471 0.0 clpE O Belongs to the ClpA ClpB family
MNLFNLIM_01472 1.5e-15
MNLFNLIM_01473 9.7e-37 ptsH G phosphocarrier protein HPR
MNLFNLIM_01474 2.4e-285 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MNLFNLIM_01475 4.4e-161 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
MNLFNLIM_01476 1.3e-126 cpoA GT4 M Glycosyltransferase, group 1 family protein
MNLFNLIM_01477 1.3e-129 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MNLFNLIM_01478 6.8e-26 ykuJ S Protein of unknown function (DUF1797)
MNLFNLIM_01479 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MNLFNLIM_01480 8.5e-89 2.7.7.65 T phosphorelay sensor kinase activity
MNLFNLIM_01482 8e-112 K IrrE N-terminal-like domain
MNLFNLIM_01483 1.2e-191 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
MNLFNLIM_01484 2.4e-19 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MNLFNLIM_01485 3.1e-60 cylB V ABC-2 type transporter
MNLFNLIM_01488 4.6e-79
MNLFNLIM_01491 6.3e-73 2.3.1.178 M GNAT acetyltransferase
MNLFNLIM_01492 6.7e-68 maa 2.3.1.79 S Maltose acetyltransferase
MNLFNLIM_01493 2.8e-56 3.6.1.27 I Acid phosphatase homologues
MNLFNLIM_01494 1.1e-80 XK27_07525 3.6.1.55 F Hydrolase, nudix family
MNLFNLIM_01496 2.2e-68 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MNLFNLIM_01497 9.9e-110 pepE 3.4.13.21 E Alpha/beta hydrolase of unknown function (DUF915)
MNLFNLIM_01498 5.9e-38 K Transcriptional regulator
MNLFNLIM_01499 5.9e-53 EGP Major Facilitator Superfamily
MNLFNLIM_01500 3.1e-167 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MNLFNLIM_01501 3.3e-281 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MNLFNLIM_01502 1.7e-212 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MNLFNLIM_01503 2.8e-186 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MNLFNLIM_01505 2e-94 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MNLFNLIM_01506 2.2e-44
MNLFNLIM_01507 1.1e-120 ica2 GT2 M Glycosyl transferase family group 2
MNLFNLIM_01508 7.9e-45 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
MNLFNLIM_01509 6.4e-221 mntH P H( )-stimulated, divalent metal cation uptake system
MNLFNLIM_01510 7.6e-61 ypbB 5.1.3.1 S Helix-turn-helix domain
MNLFNLIM_01511 2e-128 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
MNLFNLIM_01512 7.7e-12 M Lysin motif
MNLFNLIM_01513 3.7e-85 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MNLFNLIM_01514 4.4e-83 lytH 3.5.1.28 M Ami_3
MNLFNLIM_01515 5.4e-154 phoH T phosphate starvation-inducible protein PhoH
MNLFNLIM_01516 1.9e-59 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MNLFNLIM_01517 3.6e-30 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MNLFNLIM_01518 1.3e-154 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MNLFNLIM_01519 1.5e-90 recO L Involved in DNA repair and RecF pathway recombination
MNLFNLIM_01520 2.6e-07 dltX S D-Ala-teichoic acid biosynthesis protein
MNLFNLIM_01521 3.4e-219 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MNLFNLIM_01522 2e-174 dltB M MBOAT, membrane-bound O-acyltransferase family
MNLFNLIM_01523 4.9e-29 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MNLFNLIM_01524 1.5e-151 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MNLFNLIM_01525 5.3e-58 arsC 1.20.4.1 T Low molecular weight phosphatase family
MNLFNLIM_01526 2.7e-171 rpsA 1.17.7.4 J Ribosomal protein S1
MNLFNLIM_01527 1e-227 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MNLFNLIM_01528 8.5e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MNLFNLIM_01530 1.8e-22 K Acetyltransferase (GNAT) domain
MNLFNLIM_01531 3.7e-112 natA S Domain of unknown function (DUF4162)
MNLFNLIM_01532 6.5e-80 natB CP ABC-type Na efflux pump, permease component
MNLFNLIM_01533 7e-95 EG EamA-like transporter family
MNLFNLIM_01534 4.5e-80 yjjH S Calcineurin-like phosphoesterase
MNLFNLIM_01535 1.3e-187 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MNLFNLIM_01536 2.4e-40 6.3.3.2 S ASCH
MNLFNLIM_01537 2.5e-69 lepB 3.4.21.89 U Signal peptidase, peptidase S26
MNLFNLIM_01538 8.2e-117 degV S EDD domain protein, DegV family
MNLFNLIM_01539 8.9e-40 K Transcriptional regulator
MNLFNLIM_01540 9.4e-202 FbpA K Fibronectin-binding protein
MNLFNLIM_01541 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MNLFNLIM_01542 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MNLFNLIM_01543 4.2e-83 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MNLFNLIM_01544 1e-39 ypaA S Protein of unknown function (DUF1304)
MNLFNLIM_01546 6.3e-310 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MNLFNLIM_01547 1.5e-167 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MNLFNLIM_01548 0.0 dnaE 2.7.7.7 L DNA polymerase
MNLFNLIM_01549 4.3e-15 S Protein of unknown function (DUF2929)
MNLFNLIM_01550 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MNLFNLIM_01551 4.3e-203 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MNLFNLIM_01552 1.4e-40 XK27_04120 S Putative amino acid metabolism
MNLFNLIM_01553 1.7e-159 iscS 2.8.1.7 E Aminotransferase class V
MNLFNLIM_01554 4.6e-91 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MNLFNLIM_01556 2.6e-81 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
MNLFNLIM_01557 3.6e-129 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MNLFNLIM_01558 2.5e-160 nhaC C Na H antiporter NhaC
MNLFNLIM_01559 7e-127 corA P CorA-like Mg2+ transporter protein
MNLFNLIM_01560 1.5e-298 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MNLFNLIM_01561 6.9e-205 hisS 6.1.1.21 J histidyl-tRNA synthetase
MNLFNLIM_01562 2.8e-150 S Tetratricopeptide repeat protein
MNLFNLIM_01563 4.9e-136 EG EamA-like transporter family
MNLFNLIM_01564 2.5e-70 alkD L DNA alkylation repair enzyme
MNLFNLIM_01565 6.5e-184 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MNLFNLIM_01566 1.3e-103 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MNLFNLIM_01567 3e-77 trmK 2.1.1.217 S SAM-dependent methyltransferase
MNLFNLIM_01568 1.1e-149 EGP Sugar (and other) transporter
MNLFNLIM_01571 6.1e-39
MNLFNLIM_01572 5.9e-257 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
MNLFNLIM_01573 3.3e-22 S Family of unknown function (DUF5322)
MNLFNLIM_01574 1.4e-36 rnhA 3.1.26.4 L Ribonuclease HI
MNLFNLIM_01575 2.7e-173 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MNLFNLIM_01576 1.1e-35 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MNLFNLIM_01578 2.4e-88 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MNLFNLIM_01579 1.8e-172 patA 2.6.1.1 E Aminotransferase
MNLFNLIM_01580 8.6e-115 glcR K DeoR C terminal sensor domain
MNLFNLIM_01581 8.3e-144 ppaC 3.6.1.1 C inorganic pyrophosphatase
MNLFNLIM_01582 1.3e-134 K Transcriptional regulator
MNLFNLIM_01583 9.7e-88 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MNLFNLIM_01584 1.8e-85 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MNLFNLIM_01585 1.5e-190 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MNLFNLIM_01586 2.2e-114 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MNLFNLIM_01587 3.5e-204 pyrP F Permease
MNLFNLIM_01588 1.3e-75 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MNLFNLIM_01589 3.6e-128 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MNLFNLIM_01590 2.3e-43 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MNLFNLIM_01591 2.5e-56 3.1.3.18 J HAD-hyrolase-like
MNLFNLIM_01592 2.3e-54 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MNLFNLIM_01593 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MNLFNLIM_01594 2.2e-78 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MNLFNLIM_01595 1.5e-118 prmA J Ribosomal protein L11 methyltransferase
MNLFNLIM_01596 3.8e-42 XK27_03960 S Protein of unknown function (DUF3013)
MNLFNLIM_01597 5.1e-144 iunH2 3.2.2.1 F nucleoside hydrolase
MNLFNLIM_01598 6.4e-12
MNLFNLIM_01599 1.7e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MNLFNLIM_01600 1.8e-97 udk 2.7.1.48 F Cytidine monophosphokinase
MNLFNLIM_01601 1.2e-128 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MNLFNLIM_01602 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MNLFNLIM_01603 7.4e-173 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MNLFNLIM_01604 6.9e-43 yodB K Transcriptional regulator, HxlR family
MNLFNLIM_01605 3.6e-67 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
MNLFNLIM_01606 1.7e-86 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MNLFNLIM_01609 1.7e-15
MNLFNLIM_01611 1.2e-277 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MNLFNLIM_01612 4.3e-41 S Repeat protein
MNLFNLIM_01613 1.6e-56 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
MNLFNLIM_01614 3.3e-71 csm6 S Psort location Cytoplasmic, score
MNLFNLIM_01615 4.1e-31 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MNLFNLIM_01616 1.9e-87 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MNLFNLIM_01617 5e-70 csm5 L RAMP superfamily
MNLFNLIM_01618 5.1e-61 csm4 L CRISPR-associated RAMP protein, Csm4 family
MNLFNLIM_01619 9.8e-70 csm3 L RAMP superfamily
MNLFNLIM_01620 6e-29 csm2 L Csm2 Type III-A
MNLFNLIM_01621 2.5e-205 csm1 S CRISPR-associated protein Csm1 family
MNLFNLIM_01622 6.5e-34 cas6 S Pfam:DUF2276
MNLFNLIM_01623 1.5e-205 G PTS system Galactitol-specific IIC component
MNLFNLIM_01624 5.6e-210 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MNLFNLIM_01625 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MNLFNLIM_01626 3.3e-86 dprA LU DNA protecting protein DprA
MNLFNLIM_01627 4.9e-97 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MNLFNLIM_01628 2.1e-133 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MNLFNLIM_01629 3.6e-24 yozE S Belongs to the UPF0346 family
MNLFNLIM_01630 1.2e-53 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
MNLFNLIM_01631 2.9e-80 ypmR E GDSL-like Lipase/Acylhydrolase
MNLFNLIM_01633 2.3e-112 S Aldo keto reductase
MNLFNLIM_01634 2.7e-34 K helix_turn_helix, mercury resistance
MNLFNLIM_01635 3.4e-131 yvgN C Aldo keto reductase
MNLFNLIM_01636 1.2e-56 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MNLFNLIM_01637 2.6e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MNLFNLIM_01638 7.2e-275 yfmR S ABC transporter, ATP-binding protein
MNLFNLIM_01639 3e-133 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MNLFNLIM_01640 5.3e-107 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MNLFNLIM_01641 1.3e-106 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MNLFNLIM_01642 1.8e-68 xerD L Phage integrase, N-terminal SAM-like domain
MNLFNLIM_01644 1.8e-56 yqeY S YqeY-like protein
MNLFNLIM_01645 4.7e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MNLFNLIM_01646 1.1e-115 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MNLFNLIM_01649 6.8e-101 epsJ1 M Glycosyltransferase like family 2
MNLFNLIM_01650 8e-87 M Glycosyltransferase sugar-binding region containing DXD motif
MNLFNLIM_01651 2.6e-90 M transferase activity, transferring glycosyl groups
MNLFNLIM_01652 9.6e-126 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MNLFNLIM_01653 2.2e-77 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MNLFNLIM_01654 2.2e-82 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MNLFNLIM_01655 8.5e-56 dnaD L DnaD domain protein
MNLFNLIM_01656 7.6e-236 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
MNLFNLIM_01657 5.8e-142 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
MNLFNLIM_01658 1.9e-33 ypmB S Protein conserved in bacteria
MNLFNLIM_01659 3.1e-226 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MNLFNLIM_01660 4e-93 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
MNLFNLIM_01661 2.2e-62 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
MNLFNLIM_01662 1.2e-43 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
MNLFNLIM_01663 1.9e-136 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
MNLFNLIM_01664 1.3e-113 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MNLFNLIM_01665 3.5e-103 holA 2.7.7.7 L DNA polymerase III delta subunit
MNLFNLIM_01666 9.4e-157 comEC S Competence protein ComEC
MNLFNLIM_01667 2e-69 comEB 3.5.4.12 F ComE operon protein 2
MNLFNLIM_01668 1.2e-49 comEA L Competence protein ComEA
MNLFNLIM_01669 4.2e-266 argS 6.1.1.19 J Arginyl-tRNA synthetase
MNLFNLIM_01670 4e-58 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MNLFNLIM_01671 2.9e-20
MNLFNLIM_01673 3e-122 K LysR substrate binding domain
MNLFNLIM_01674 7.5e-195 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MNLFNLIM_01675 1.7e-65 S Acyltransferase family
MNLFNLIM_01676 1.2e-19 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MNLFNLIM_01679 2.1e-07
MNLFNLIM_01680 1.1e-259 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MNLFNLIM_01681 6.1e-169 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MNLFNLIM_01682 2e-131 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MNLFNLIM_01683 3e-282 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MNLFNLIM_01684 1.5e-76 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MNLFNLIM_01685 3.6e-95 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MNLFNLIM_01686 1.1e-40 yabR J RNA binding
MNLFNLIM_01687 1e-21 divIC D Septum formation initiator
MNLFNLIM_01688 3.6e-31 yabO J S4 domain protein
MNLFNLIM_01689 6.6e-141 yabM S Polysaccharide biosynthesis protein
MNLFNLIM_01690 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MNLFNLIM_01691 5.5e-74 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MNLFNLIM_01692 3.6e-158 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MNLFNLIM_01693 2.5e-86 S (CBS) domain
MNLFNLIM_01694 1.4e-141 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MNLFNLIM_01695 2.2e-208 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MNLFNLIM_01696 5.5e-53 perR P Belongs to the Fur family
MNLFNLIM_01697 9.9e-58 S LexA-binding, inner membrane-associated putative hydrolase
MNLFNLIM_01698 2e-60 sbcC L Putative exonuclease SbcCD, C subunit
MNLFNLIM_01699 9.4e-34 sbcC L Putative exonuclease SbcCD, C subunit
MNLFNLIM_01700 8.9e-116 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MNLFNLIM_01701 4.6e-36 M LysM domain protein
MNLFNLIM_01702 2.5e-277 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MNLFNLIM_01703 2.4e-85 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
MNLFNLIM_01704 4.6e-35 ygfC K Bacterial regulatory proteins, tetR family
MNLFNLIM_01705 9.6e-112 hrtB V ABC transporter permease
MNLFNLIM_01706 2.3e-87 devA 3.6.3.25 V ABC transporter, ATP-binding protein
MNLFNLIM_01707 0.0 helD 3.6.4.12 L DNA helicase
MNLFNLIM_01708 1.5e-245 yjbQ P TrkA C-terminal domain protein
MNLFNLIM_01709 8.8e-30
MNLFNLIM_01710 1.1e-60 rpsI J Belongs to the universal ribosomal protein uS9 family
MNLFNLIM_01711 5.5e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MNLFNLIM_01712 5.5e-125 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MNLFNLIM_01713 3.7e-108 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MNLFNLIM_01714 1.1e-110 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MNLFNLIM_01715 4e-100 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MNLFNLIM_01716 4.8e-53 rplQ J Ribosomal protein L17
MNLFNLIM_01717 1.3e-155 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MNLFNLIM_01718 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MNLFNLIM_01719 4.4e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MNLFNLIM_01720 2.5e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MNLFNLIM_01721 4.8e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MNLFNLIM_01722 4.4e-107 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MNLFNLIM_01723 1.7e-206 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MNLFNLIM_01724 1e-67 rplO J Binds to the 23S rRNA
MNLFNLIM_01725 2.1e-22 rpmD J Ribosomal protein L30
MNLFNLIM_01726 1.3e-82 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MNLFNLIM_01727 9.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MNLFNLIM_01728 3.2e-87 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MNLFNLIM_01729 2.5e-65 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MNLFNLIM_01730 4.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MNLFNLIM_01731 1.3e-91 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MNLFNLIM_01732 7e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MNLFNLIM_01733 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MNLFNLIM_01734 8e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MNLFNLIM_01735 9e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
MNLFNLIM_01736 6.2e-73 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MNLFNLIM_01737 5.2e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MNLFNLIM_01738 1.5e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MNLFNLIM_01739 1e-44 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MNLFNLIM_01740 1.4e-142 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MNLFNLIM_01741 2.9e-39 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MNLFNLIM_01742 1e-100 rplD J Forms part of the polypeptide exit tunnel
MNLFNLIM_01743 4.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MNLFNLIM_01744 2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
MNLFNLIM_01745 4.3e-167 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MNLFNLIM_01746 6.5e-79 K rpiR family
MNLFNLIM_01747 2.6e-54 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
MNLFNLIM_01748 2.7e-145 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
MNLFNLIM_01749 6.5e-21 K Acetyltransferase (GNAT) domain
MNLFNLIM_01750 3.8e-182 steT E amino acid
MNLFNLIM_01751 9.6e-78 glnP P ABC transporter permease
MNLFNLIM_01752 1.2e-85 gluC P ABC transporter permease
MNLFNLIM_01753 1.9e-99 glnH ET ABC transporter
MNLFNLIM_01754 1.3e-102 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MNLFNLIM_01755 1.3e-09
MNLFNLIM_01756 2.5e-97
MNLFNLIM_01757 3e-12 3.2.1.14 GH18
MNLFNLIM_01758 5.4e-53 zur P Belongs to the Fur family
MNLFNLIM_01759 6.3e-212 yfnA E Amino Acid
MNLFNLIM_01760 3.6e-250 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MNLFNLIM_01761 0.0 L Helicase C-terminal domain protein
MNLFNLIM_01762 6e-79 ptp2 3.1.3.48 T Tyrosine phosphatase family
MNLFNLIM_01763 9.3e-181 yhdP S Transporter associated domain
MNLFNLIM_01764 9.8e-24
MNLFNLIM_01765 6.9e-74 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MNLFNLIM_01766 1.6e-131 bacI V MacB-like periplasmic core domain
MNLFNLIM_01767 3.3e-97 V ABC transporter
MNLFNLIM_01768 2e-64 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MNLFNLIM_01769 5.2e-156 gmuE 2.7.1.2, 2.7.1.4 GK ROK family
MNLFNLIM_01770 4.7e-140 V MatE
MNLFNLIM_01771 1.2e-43 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MNLFNLIM_01772 5e-87 S Alpha beta hydrolase
MNLFNLIM_01773 4.6e-94 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MNLFNLIM_01774 1.9e-174 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MNLFNLIM_01775 3e-111 argE 3.5.1.18 E Peptidase dimerisation domain
MNLFNLIM_01776 1.4e-101 IQ Enoyl-(Acyl carrier protein) reductase
MNLFNLIM_01777 2.5e-33 XK27_01315 S Protein of unknown function (DUF2829)
MNLFNLIM_01778 4.8e-53 queT S QueT transporter
MNLFNLIM_01780 1.5e-65 degV S Uncharacterised protein, DegV family COG1307
MNLFNLIM_01781 8.8e-22 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MNLFNLIM_01782 2.7e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MNLFNLIM_01783 1.9e-34 trxA O Belongs to the thioredoxin family
MNLFNLIM_01784 3.8e-87 S Sucrose-6F-phosphate phosphohydrolase
MNLFNLIM_01785 2.8e-125 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MNLFNLIM_01786 1.3e-49 S Threonine/Serine exporter, ThrE
MNLFNLIM_01787 4.3e-82 thrE S Putative threonine/serine exporter
MNLFNLIM_01788 3.1e-27 cspC K Cold shock protein
MNLFNLIM_01789 9.1e-89 sirR K Helix-turn-helix diphteria tox regulatory element
MNLFNLIM_01790 3.1e-95 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
MNLFNLIM_01791 3.1e-23
MNLFNLIM_01792 2.1e-58 3.6.1.27 I phosphatase
MNLFNLIM_01793 3.1e-25
MNLFNLIM_01794 2.1e-66 I alpha/beta hydrolase fold
MNLFNLIM_01795 1e-38 azlD S branched-chain amino acid
MNLFNLIM_01796 1.9e-104 azlC E AzlC protein
MNLFNLIM_01797 3.5e-17
MNLFNLIM_01798 4.9e-119 xth 3.1.11.2 L exodeoxyribonuclease III
MNLFNLIM_01799 9.2e-91 V domain protein
MNLFNLIM_01804 8.1e-09 S zinc-ribbon domain
MNLFNLIM_01806 4e-11 S Mor transcription activator family
MNLFNLIM_01807 2.3e-59 yfjR K WYL domain
MNLFNLIM_01808 6e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MNLFNLIM_01809 2.7e-171 malY 4.4.1.8 E Aminotransferase, class I
MNLFNLIM_01810 6.9e-118 K AI-2E family transporter
MNLFNLIM_01811 1.2e-60 EG EamA-like transporter family
MNLFNLIM_01812 4.4e-75 L haloacid dehalogenase-like hydrolase
MNLFNLIM_01813 4.4e-117 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
MNLFNLIM_01814 4.3e-66 1.5.1.38 S NADPH-dependent FMN reductase
MNLFNLIM_01815 3.7e-164 C Luciferase-like monooxygenase
MNLFNLIM_01816 1.3e-41 K Transcriptional regulator, HxlR family
MNLFNLIM_01817 1.7e-171 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MNLFNLIM_01818 3.4e-103 ydhQ K UbiC transcription regulator-associated domain protein
MNLFNLIM_01819 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
MNLFNLIM_01820 7e-82 pncA Q isochorismatase
MNLFNLIM_01821 4.6e-63 3.1.3.73 G phosphoglycerate mutase
MNLFNLIM_01822 9.5e-259 treB G phosphotransferase system
MNLFNLIM_01823 5.7e-84 treR K UTRA
MNLFNLIM_01824 2.2e-251 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
MNLFNLIM_01825 2.5e-167 mdtG EGP Major facilitator Superfamily
MNLFNLIM_01827 2.6e-167 XK27_08315 M Sulfatase
MNLFNLIM_01828 3.3e-21 XK27_08315 M Sulfatase
MNLFNLIM_01829 2.4e-56 S peptidoglycan catabolic process
MNLFNLIM_01831 1.1e-150 M BCCT, betaine/carnitine/choline family transporter
MNLFNLIM_01832 1.5e-84 M Nucleotidyl transferase
MNLFNLIM_01833 7.8e-32 licA 2.7.1.89 M Choline/ethanolamine kinase
MNLFNLIM_01834 1.3e-121 licA 2.7.1.89 M Choline/ethanolamine kinase
MNLFNLIM_01835 9.5e-89 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MNLFNLIM_01836 1.2e-167 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
MNLFNLIM_01837 2.9e-126 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MNLFNLIM_01838 4.1e-177 thrC 4.2.3.1 E Threonine synthase
MNLFNLIM_01839 1.1e-30 S Bacterial membrane protein YfhO
MNLFNLIM_01840 6.8e-103 S Bacterial membrane protein YfhO
MNLFNLIM_01841 3.6e-14
MNLFNLIM_01842 6.9e-77 S Psort location CytoplasmicMembrane, score
MNLFNLIM_01843 1.9e-146 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
MNLFNLIM_01844 7.5e-39 2.7.7.65 T phosphorelay sensor kinase activity
MNLFNLIM_01845 7e-157 XK27_09615 S reductase
MNLFNLIM_01846 3.8e-51 XK27_09620 S NADPH-dependent FMN reductase
MNLFNLIM_01847 5.6e-97 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MNLFNLIM_01848 7.3e-161 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MNLFNLIM_01849 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MNLFNLIM_01851 1.8e-153 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
MNLFNLIM_01852 1.2e-194 glf 5.4.99.9 M UDP-galactopyranose mutase
MNLFNLIM_01853 7.3e-38 S Acyltransferase family
MNLFNLIM_01854 1.2e-43 S Peptidase_C39 like family
MNLFNLIM_01856 8.5e-64 M Glycosyltransferase like family 2
MNLFNLIM_01857 2.4e-73 M LicD family
MNLFNLIM_01858 6.9e-58 cps3F
MNLFNLIM_01859 1.6e-30 S Phage regulatory protein Rha (Phage_pRha)
MNLFNLIM_01860 5.3e-08 S Helix-turn-helix domain
MNLFNLIM_01861 4.2e-24 K Cro/C1-type HTH DNA-binding domain
MNLFNLIM_01862 2.2e-125 sip L Belongs to the 'phage' integrase family
MNLFNLIM_01863 1.6e-55 jag S R3H domain protein
MNLFNLIM_01864 1.5e-56 ohrR K helix_turn_helix multiple antibiotic resistance protein
MNLFNLIM_01865 2.6e-31 azlD S Branched-chain amino acid transport protein (AzlD)
MNLFNLIM_01866 5.1e-77 azlC E branched-chain amino acid
MNLFNLIM_01867 1e-57 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
MNLFNLIM_01868 2.1e-113 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
MNLFNLIM_01869 6.8e-293 lai 4.2.1.53 S Myosin-crossreactive antigen
MNLFNLIM_01870 3.5e-33 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
MNLFNLIM_01871 2.4e-193 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
MNLFNLIM_01872 7e-110 endA F DNA RNA non-specific endonuclease
MNLFNLIM_01874 1.9e-208 brnQ U Component of the transport system for branched-chain amino acids
MNLFNLIM_01875 1.7e-61 K Bacterial regulatory proteins, tetR family
MNLFNLIM_01876 1.9e-114 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
MNLFNLIM_01877 7.6e-151 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
MNLFNLIM_01878 3.3e-69 dhaL 2.7.1.121 S Dak2
MNLFNLIM_01879 1.4e-49 dhaM 2.7.1.121 S PTS system fructose IIA component
MNLFNLIM_01880 5.5e-103 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MNLFNLIM_01881 8.3e-176 yjcE P Sodium proton antiporter
MNLFNLIM_01882 2.6e-162 mtlR K Mga helix-turn-helix domain
MNLFNLIM_01883 7.6e-37 mtlR K Mga helix-turn-helix domain
MNLFNLIM_01884 2.3e-302 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MNLFNLIM_01885 4.5e-102 tcyB E ABC transporter
MNLFNLIM_01886 2e-100 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MNLFNLIM_01887 5.7e-96 tcyA ET Belongs to the bacterial solute-binding protein 3 family
MNLFNLIM_01888 2.1e-38 K Transcriptional regulator
MNLFNLIM_01889 2.2e-107 terC P Integral membrane protein TerC family
MNLFNLIM_01890 1.1e-261 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
MNLFNLIM_01891 2.8e-65 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MNLFNLIM_01892 2.4e-185 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
MNLFNLIM_01893 4e-41 gntR1 K Transcriptional regulator, GntR family
MNLFNLIM_01894 1.8e-95 V ABC transporter, ATP-binding protein
MNLFNLIM_01895 6e-07
MNLFNLIM_01897 1.1e-39 ybjQ S Belongs to the UPF0145 family
MNLFNLIM_01898 1.1e-157 manA 5.3.1.8 G mannose-6-phosphate isomerase
MNLFNLIM_01899 6.6e-97 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MNLFNLIM_01900 4e-157 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MNLFNLIM_01901 4.5e-140 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MNLFNLIM_01902 3.7e-34
MNLFNLIM_01903 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MNLFNLIM_01904 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MNLFNLIM_01905 5.2e-63 srtA 3.4.22.70 M sortase family
MNLFNLIM_01907 6.8e-72 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
MNLFNLIM_01908 3.3e-60 yvdD 3.2.2.10 S Possible lysine decarboxylase
MNLFNLIM_01909 0.0 pacL 3.6.3.8 P P-type ATPase
MNLFNLIM_01910 1.2e-108 3.1.4.46 C phosphodiesterase
MNLFNLIM_01911 1.2e-126 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MNLFNLIM_01912 3.6e-102 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
MNLFNLIM_01913 9.5e-68 noc K Belongs to the ParB family
MNLFNLIM_01914 6.5e-118 soj D Sporulation initiation inhibitor
MNLFNLIM_01915 9.1e-108 spo0J K Belongs to the ParB family
MNLFNLIM_01916 1.8e-24 yyzM S Bacterial protein of unknown function (DUF951)
MNLFNLIM_01917 2.4e-190 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MNLFNLIM_01918 4.2e-53 XK27_01040 S Protein of unknown function (DUF1129)
MNLFNLIM_01919 7.3e-14 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
MNLFNLIM_01920 1.5e-38
MNLFNLIM_01921 1e-103 psaA P Belongs to the bacterial solute-binding protein 9 family
MNLFNLIM_01922 2.9e-98 fhuC P ABC transporter
MNLFNLIM_01923 2.8e-103 znuB U ABC 3 transport family
MNLFNLIM_01924 1.5e-55 S ECF transporter, substrate-specific component
MNLFNLIM_01925 8.8e-102 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MNLFNLIM_01926 2.9e-89 S NADPH-dependent FMN reductase
MNLFNLIM_01927 2.1e-27 yraB K transcriptional regulator
MNLFNLIM_01928 1.5e-67 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
MNLFNLIM_01930 4.5e-154 EGP Major facilitator Superfamily
MNLFNLIM_01931 2.3e-58 S Haloacid dehalogenase-like hydrolase
MNLFNLIM_01932 2.6e-88 yvyE 3.4.13.9 S YigZ family
MNLFNLIM_01933 2.1e-37 S CAAX protease self-immunity
MNLFNLIM_01934 1.5e-117 cps1D M Domain of unknown function (DUF4422)
MNLFNLIM_01935 1.3e-62 S Glycosyltransferase like family 2
MNLFNLIM_01936 2.5e-137 tetA EGP Major facilitator Superfamily
MNLFNLIM_01937 3.9e-32 yvdC S MazG nucleotide pyrophosphohydrolase domain
MNLFNLIM_01938 2.1e-213 yjeM E Amino Acid
MNLFNLIM_01939 3.1e-188 glnPH2 P ABC transporter permease
MNLFNLIM_01940 2.3e-112 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MNLFNLIM_01941 1.7e-44 E GDSL-like Lipase/Acylhydrolase
MNLFNLIM_01942 3.9e-133 coaA 2.7.1.33 F Pantothenic acid kinase
MNLFNLIM_01943 3.4e-275 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MNLFNLIM_01944 8.7e-51 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
MNLFNLIM_01945 1.8e-49 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
MNLFNLIM_01946 7.2e-38 L hmm pf00665
MNLFNLIM_01952 7.9e-07
MNLFNLIM_01953 1.1e-262 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MNLFNLIM_01954 1.7e-54 rplI J Binds to the 23S rRNA
MNLFNLIM_01955 1.4e-206 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MNLFNLIM_01956 4e-64 C FMN binding
MNLFNLIM_01957 9.6e-231 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MNLFNLIM_01959 1.5e-156 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MNLFNLIM_01960 1.6e-59 ykhA 3.1.2.20 I Thioesterase superfamily
MNLFNLIM_01961 1.9e-10 S CAAX protease self-immunity
MNLFNLIM_01962 2.5e-82 S Belongs to the UPF0246 family
MNLFNLIM_01963 3.4e-94 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
MNLFNLIM_01964 1.1e-129 yxjG 2.1.1.14 E Cobalamin-independent synthase, Catalytic domain
MNLFNLIM_01965 2.4e-73 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
MNLFNLIM_01966 1.1e-103 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
MNLFNLIM_01967 2.2e-87 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
MNLFNLIM_01968 1.2e-159 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
MNLFNLIM_01969 1.5e-20 3.1.3.48 K Transcriptional regulator
MNLFNLIM_01970 2.7e-23 3.1.3.48 K Transcriptional regulator
MNLFNLIM_01971 9e-198 1.3.5.4 C FMN_bind
MNLFNLIM_01972 2.9e-117 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
MNLFNLIM_01973 9.9e-201 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
MNLFNLIM_01974 4.3e-140 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MNLFNLIM_01975 1.9e-80 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
MNLFNLIM_01976 5.8e-64 2.7.1.191 G PTS system sorbose subfamily IIB component
MNLFNLIM_01977 4.4e-101 G PTS system sorbose-specific iic component
MNLFNLIM_01978 3.2e-123 G PTS system mannose/fructose/sorbose family IID component
MNLFNLIM_01979 7.5e-39 2.7.1.191 G PTS system fructose IIA component
MNLFNLIM_01980 4.2e-231 malL 3.2.1.10 GH13 G Psort location Cytoplasmic, score
MNLFNLIM_01981 5.3e-112 lacI3 K helix_turn _helix lactose operon repressor
MNLFNLIM_01982 9.2e-65 glpQ 3.1.4.46 C phosphodiesterase
MNLFNLIM_01983 8.1e-46 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
MNLFNLIM_01984 5e-77 hchA S intracellular protease amidase
MNLFNLIM_01985 1.2e-21 K transcriptional regulator
MNLFNLIM_01986 2.8e-149 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MNLFNLIM_01987 1.5e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MNLFNLIM_01988 3.3e-21 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MNLFNLIM_01989 2.1e-250 ctpA 3.6.3.54 P P-type ATPase
MNLFNLIM_01990 1.4e-65 pgm3 G phosphoglycerate mutase family
MNLFNLIM_01991 3.9e-57 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
MNLFNLIM_01992 1.1e-85 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MNLFNLIM_01993 2.3e-217 yifK E Amino acid permease
MNLFNLIM_01994 4.7e-203 oppA E ABC transporter, substratebinding protein
MNLFNLIM_01995 4.6e-142 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
MNLFNLIM_01996 3e-20 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
MNLFNLIM_01997 3.8e-146 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
MNLFNLIM_01998 1.3e-180 oppD P Belongs to the ABC transporter superfamily
MNLFNLIM_01999 2.2e-155 oppF P Belongs to the ABC transporter superfamily
MNLFNLIM_02000 9.2e-16 psiE S Phosphate-starvation-inducible E
MNLFNLIM_02001 3.5e-207 mmuP E amino acid
MNLFNLIM_02002 9e-114 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
MNLFNLIM_02003 4.5e-39 K LytTr DNA-binding domain
MNLFNLIM_02004 8.6e-17 S Protein of unknown function (DUF3021)
MNLFNLIM_02005 1.3e-150 yfeX P Peroxidase
MNLFNLIM_02006 3e-30 tetR K Transcriptional regulator C-terminal region
MNLFNLIM_02007 4.1e-47 S Short repeat of unknown function (DUF308)
MNLFNLIM_02008 6.2e-53 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MNLFNLIM_02009 6.2e-163 oxlT P Major Facilitator Superfamily
MNLFNLIM_02010 2.6e-67 ybbL S ABC transporter
MNLFNLIM_02011 1.9e-101 ybbM S Uncharacterised protein family (UPF0014)
MNLFNLIM_02012 4.2e-43 ytcD K HxlR-like helix-turn-helix
MNLFNLIM_02013 2.4e-118 ytbE S reductase
MNLFNLIM_02014 9.8e-72 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MNLFNLIM_02016 2e-12 3.1.3.48 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MNLFNLIM_02017 2.7e-70 mltD CBM50 M NlpC P60 family protein
MNLFNLIM_02018 1.4e-129 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MNLFNLIM_02019 1.1e-164 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MNLFNLIM_02020 3.1e-75 ung2 3.2.2.27 L Uracil-DNA glycosylase
MNLFNLIM_02021 1e-47 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
MNLFNLIM_02022 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MNLFNLIM_02023 9.4e-108 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MNLFNLIM_02024 6.5e-37 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MNLFNLIM_02025 1.5e-46 S CRISPR-associated protein (Cas_Csn2)
MNLFNLIM_02026 1.3e-38 K transcriptional regulator PadR family
MNLFNLIM_02027 4.2e-19 XK27_06920 S Protein of unknown function (DUF1700)
MNLFNLIM_02028 4.1e-16 S Putative adhesin
MNLFNLIM_02029 2.2e-16 pspC KT PspC domain
MNLFNLIM_02031 3.9e-13 S Enterocin A Immunity
MNLFNLIM_02032 5.2e-236 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MNLFNLIM_02033 7.4e-261 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
MNLFNLIM_02034 2.1e-99 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MNLFNLIM_02035 8.2e-167 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MNLFNLIM_02036 1.5e-120 potB P ABC transporter permease
MNLFNLIM_02037 1.7e-103 potC U Binding-protein-dependent transport system inner membrane component
MNLFNLIM_02038 1.2e-33 potD P ABC transporter
MNLFNLIM_02039 1.3e-116 potD P ABC transporter
MNLFNLIM_02040 3.5e-132 ABC-SBP S ABC transporter
MNLFNLIM_02041 4.3e-113 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
MNLFNLIM_02042 3.9e-107 XK27_08845 S ABC transporter, ATP-binding protein
MNLFNLIM_02043 4.4e-67 M ErfK YbiS YcfS YnhG
MNLFNLIM_02044 1.1e-54 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MNLFNLIM_02045 1.4e-224 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MNLFNLIM_02046 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MNLFNLIM_02047 1.5e-102 pgm3 G phosphoglycerate mutase
MNLFNLIM_02048 2.7e-56 S CAAX protease self-immunity
MNLFNLIM_02049 5.7e-48 C Flavodoxin
MNLFNLIM_02050 1.4e-58 yphH S Cupin domain
MNLFNLIM_02051 1e-45 yphJ 4.1.1.44 S decarboxylase
MNLFNLIM_02052 2e-144 2.1.1.14 E methionine synthase, vitamin-B12 independent
MNLFNLIM_02053 1.8e-108 metQ1 P Belongs to the nlpA lipoprotein family
MNLFNLIM_02054 2.6e-149 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MNLFNLIM_02055 1.3e-69 metI P ABC transporter permease
MNLFNLIM_02056 5.7e-134 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
MNLFNLIM_02057 3e-84 drgA C nitroreductase
MNLFNLIM_02058 3.7e-82 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
MNLFNLIM_02059 1e-106 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
MNLFNLIM_02060 8.1e-172 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MNLFNLIM_02061 6.5e-261 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
MNLFNLIM_02063 6.2e-151 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MNLFNLIM_02064 2.4e-31 metI U ABC transporter permease
MNLFNLIM_02065 8.2e-127 metQ M Belongs to the nlpA lipoprotein family
MNLFNLIM_02066 6.3e-54 S Protein of unknown function (DUF4256)

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)