ORF_ID e_value Gene_name EC_number CAZy COGs Description
NNBOFHNM_00001 1.6e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NNBOFHNM_00002 9.7e-24 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NNBOFHNM_00003 4.3e-137 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
NNBOFHNM_00004 7.3e-105
NNBOFHNM_00005 7.2e-117
NNBOFHNM_00006 1.3e-41 dut S dUTPase
NNBOFHNM_00007 2.1e-94 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NNBOFHNM_00008 3.7e-46 yqhY S Asp23 family, cell envelope-related function
NNBOFHNM_00009 1.9e-36 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NNBOFHNM_00010 1.7e-103 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NNBOFHNM_00011 1.2e-146 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NNBOFHNM_00012 1.2e-16 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NNBOFHNM_00013 4.7e-83 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NNBOFHNM_00014 1.2e-120 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NNBOFHNM_00015 6.6e-49 argR K Regulates arginine biosynthesis genes
NNBOFHNM_00016 4.2e-178 recN L May be involved in recombinational repair of damaged DNA
NNBOFHNM_00017 1.2e-82 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NNBOFHNM_00018 2.2e-30 ynzC S UPF0291 protein
NNBOFHNM_00019 5.9e-27 yneF S UPF0154 protein
NNBOFHNM_00020 1.8e-91 engB D Necessary for normal cell division and for the maintenance of normal septation
NNBOFHNM_00021 5.4e-44 MA20_27270 S mazG nucleotide pyrophosphohydrolase
NNBOFHNM_00022 1.2e-74 yciQ P membrane protein (DUF2207)
NNBOFHNM_00023 3e-19 D nuclear chromosome segregation
NNBOFHNM_00024 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NNBOFHNM_00025 1.6e-38 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NNBOFHNM_00026 7.4e-70 gluP 3.4.21.105 S Peptidase, S54 family
NNBOFHNM_00027 1.5e-25 yqgQ S Bacterial protein of unknown function (DUF910)
NNBOFHNM_00028 4.7e-158 glk 2.7.1.2 G Glucokinase
NNBOFHNM_00029 2.7e-46 yqhL P Rhodanese-like protein
NNBOFHNM_00030 9.7e-17 WQ51_02665 S Protein of unknown function (DUF3042)
NNBOFHNM_00031 1.9e-111 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NNBOFHNM_00032 1.8e-205 ynbB 4.4.1.1 P aluminum resistance
NNBOFHNM_00033 1.3e-45 glnR K Transcriptional regulator
NNBOFHNM_00034 2e-247 glnA 6.3.1.2 E glutamine synthetase
NNBOFHNM_00036 5.8e-37 ogt 2.1.1.63 H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NNBOFHNM_00037 2.7e-48 S Domain of unknown function (DUF956)
NNBOFHNM_00038 6.3e-115 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NNBOFHNM_00039 7.2e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NNBOFHNM_00040 3.8e-105 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NNBOFHNM_00041 5.1e-102 cdsA 2.7.7.41 S Belongs to the CDS family
NNBOFHNM_00042 2.6e-156 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NNBOFHNM_00043 5.9e-260 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NNBOFHNM_00044 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NNBOFHNM_00045 2.7e-66 rimP J Required for maturation of 30S ribosomal subunits
NNBOFHNM_00046 4.8e-170 nusA K Participates in both transcription termination and antitermination
NNBOFHNM_00047 1.4e-39 ylxR K Protein of unknown function (DUF448)
NNBOFHNM_00048 6.8e-26 ylxQ J ribosomal protein
NNBOFHNM_00049 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NNBOFHNM_00050 1.3e-55 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NNBOFHNM_00051 1.4e-119 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NNBOFHNM_00052 2.5e-95 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NNBOFHNM_00053 1.4e-131 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NNBOFHNM_00054 4.2e-56 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NNBOFHNM_00055 1.5e-274 dnaK O Heat shock 70 kDa protein
NNBOFHNM_00056 1.2e-160 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NNBOFHNM_00057 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NNBOFHNM_00059 9.2e-206 glnP P ABC transporter
NNBOFHNM_00060 2.6e-119 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NNBOFHNM_00061 1.5e-31
NNBOFHNM_00062 2e-111 ampC V Beta-lactamase
NNBOFHNM_00063 3.5e-110 cobQ S glutamine amidotransferase
NNBOFHNM_00064 4.7e-220 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
NNBOFHNM_00065 6.8e-86 tdk 2.7.1.21 F thymidine kinase
NNBOFHNM_00066 2.3e-177 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NNBOFHNM_00067 1.4e-89 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NNBOFHNM_00068 7.7e-135 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NNBOFHNM_00069 5e-100 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NNBOFHNM_00070 4.5e-97 atpB C it plays a direct role in the translocation of protons across the membrane
NNBOFHNM_00071 1.8e-15 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NNBOFHNM_00072 2.4e-39 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NNBOFHNM_00073 2.7e-57 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NNBOFHNM_00074 6.3e-266 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NNBOFHNM_00075 1.3e-141 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NNBOFHNM_00076 1.7e-236 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NNBOFHNM_00077 3.9e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NNBOFHNM_00078 4.1e-15 ywzB S Protein of unknown function (DUF1146)
NNBOFHNM_00079 9.3e-197 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NNBOFHNM_00080 3.4e-167 mbl D Cell shape determining protein MreB Mrl
NNBOFHNM_00081 1.2e-26 yidD S Could be involved in insertion of integral membrane proteins into the membrane
NNBOFHNM_00082 1.8e-12 S Protein of unknown function (DUF2969)
NNBOFHNM_00083 6.1e-187 rodA D Belongs to the SEDS family
NNBOFHNM_00084 3.5e-26 arsC 1.20.4.1 P Belongs to the ArsC family
NNBOFHNM_00085 5.6e-94 2.7.1.89 M Phosphotransferase enzyme family
NNBOFHNM_00086 1.1e-102 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NNBOFHNM_00087 1.4e-12 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NNBOFHNM_00088 4.4e-121 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NNBOFHNM_00089 2.7e-287 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NNBOFHNM_00090 5.8e-140 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NNBOFHNM_00091 2.2e-153 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NNBOFHNM_00092 3.3e-90 stp 3.1.3.16 T phosphatase
NNBOFHNM_00093 3.4e-191 KLT serine threonine protein kinase
NNBOFHNM_00094 1.8e-111 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NNBOFHNM_00095 3.8e-58 thiN 2.7.6.2 H thiamine pyrophosphokinase
NNBOFHNM_00096 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NNBOFHNM_00097 4.5e-53 asp S Asp23 family, cell envelope-related function
NNBOFHNM_00098 2.8e-238 yloV S DAK2 domain fusion protein YloV
NNBOFHNM_00099 3.3e-246 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NNBOFHNM_00100 1.6e-140 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NNBOFHNM_00101 7e-26 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NNBOFHNM_00102 1.1e-100 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NNBOFHNM_00103 1.8e-210 smc D Required for chromosome condensation and partitioning
NNBOFHNM_00104 9.1e-149 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NNBOFHNM_00105 7e-40 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NNBOFHNM_00106 5e-204 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NNBOFHNM_00107 3.6e-42 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NNBOFHNM_00108 1.1e-26 ylqC S Belongs to the UPF0109 family
NNBOFHNM_00109 1.9e-57 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NNBOFHNM_00110 7.3e-114 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NNBOFHNM_00111 5.7e-61 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
NNBOFHNM_00112 7e-198 yfnA E amino acid
NNBOFHNM_00113 3e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NNBOFHNM_00114 1.8e-32 rpsT J Binds directly to 16S ribosomal RNA
NNBOFHNM_00115 5.6e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NNBOFHNM_00116 5.3e-116 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NNBOFHNM_00117 3.8e-267 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NNBOFHNM_00118 4e-18 S Tetratricopeptide repeat
NNBOFHNM_00119 1.4e-215 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NNBOFHNM_00120 6e-196 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NNBOFHNM_00121 1e-197 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NNBOFHNM_00122 2.3e-249 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NNBOFHNM_00123 1.5e-300 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NNBOFHNM_00124 5e-23 ykzG S Belongs to the UPF0356 family
NNBOFHNM_00125 1.6e-24
NNBOFHNM_00126 2.2e-86 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NNBOFHNM_00127 1.3e-12 1.1.1.27 C L-malate dehydrogenase activity
NNBOFHNM_00129 1.7e-23 yktA S Belongs to the UPF0223 family
NNBOFHNM_00130 9.7e-77 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
NNBOFHNM_00131 0.0 typA T GTP-binding protein TypA
NNBOFHNM_00132 6e-148 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
NNBOFHNM_00133 7e-115 manY G PTS system
NNBOFHNM_00134 3.3e-148 manN G system, mannose fructose sorbose family IID component
NNBOFHNM_00135 1.6e-102 ftsW D Belongs to the SEDS family
NNBOFHNM_00136 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NNBOFHNM_00137 1.1e-17 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
NNBOFHNM_00138 7.2e-74 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
NNBOFHNM_00139 4e-49 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NNBOFHNM_00140 2.4e-131 ylbL T Belongs to the peptidase S16 family
NNBOFHNM_00141 2.2e-96 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NNBOFHNM_00142 2.2e-30 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NNBOFHNM_00143 6.8e-103 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NNBOFHNM_00144 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NNBOFHNM_00145 2.1e-226 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NNBOFHNM_00146 2.4e-139 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NNBOFHNM_00147 5.2e-75 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NNBOFHNM_00148 8.5e-234 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NNBOFHNM_00149 1e-152 purD 6.3.4.13 F Belongs to the GARS family
NNBOFHNM_00150 1.5e-93 S Acyltransferase family
NNBOFHNM_00151 3e-87 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NNBOFHNM_00152 2.2e-23 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NNBOFHNM_00153 3.9e-122 K LysR substrate binding domain
NNBOFHNM_00155 2.2e-20
NNBOFHNM_00156 6.2e-59 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NNBOFHNM_00157 5.8e-268 argS 6.1.1.19 J Arginyl-tRNA synthetase
NNBOFHNM_00158 1.4e-50 comEA L Competence protein ComEA
NNBOFHNM_00159 2e-69 comEB 3.5.4.12 F ComE operon protein 2
NNBOFHNM_00160 1.4e-155 comEC S Competence protein ComEC
NNBOFHNM_00161 9.3e-104 holA 2.7.7.7 L DNA polymerase III delta subunit
NNBOFHNM_00162 1.3e-113 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NNBOFHNM_00163 3e-137 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
NNBOFHNM_00164 2.8e-118 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NNBOFHNM_00165 8.1e-94 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
NNBOFHNM_00166 2.2e-227 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NNBOFHNM_00167 1.8e-36 ypmB S Protein conserved in bacteria
NNBOFHNM_00168 4e-143 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NNBOFHNM_00169 1e-235 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
NNBOFHNM_00170 5.1e-56 dnaD L DnaD domain protein
NNBOFHNM_00171 4.4e-83 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NNBOFHNM_00172 1.5e-78 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NNBOFHNM_00173 9.6e-126 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NNBOFHNM_00174 1.9e-93 M transferase activity, transferring glycosyl groups
NNBOFHNM_00175 1.4e-83 M Glycosyltransferase sugar-binding region containing DXD motif
NNBOFHNM_00176 1.3e-99 epsJ1 M Glycosyltransferase like family 2
NNBOFHNM_00179 1.1e-115 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NNBOFHNM_00180 4.7e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NNBOFHNM_00181 1.8e-56 yqeY S YqeY-like protein
NNBOFHNM_00183 3.9e-68 xerD L Phage integrase, N-terminal SAM-like domain
NNBOFHNM_00184 1e-106 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NNBOFHNM_00185 1.1e-107 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NNBOFHNM_00186 1.9e-132 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NNBOFHNM_00187 2.9e-276 yfmR S ABC transporter, ATP-binding protein
NNBOFHNM_00188 4.4e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NNBOFHNM_00189 3.2e-57 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NNBOFHNM_00190 2.5e-134 yvgN C Aldo keto reductase
NNBOFHNM_00191 2.4e-35 K helix_turn_helix, mercury resistance
NNBOFHNM_00192 4.8e-102 S Aldo keto reductase
NNBOFHNM_00194 7.2e-79 ypmR E GDSL-like Lipase/Acylhydrolase
NNBOFHNM_00195 5.7e-53 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
NNBOFHNM_00196 3.6e-24 yozE S Belongs to the UPF0346 family
NNBOFHNM_00197 4.7e-133 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NNBOFHNM_00198 1.8e-96 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NNBOFHNM_00199 6.2e-85 dprA LU DNA protecting protein DprA
NNBOFHNM_00200 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NNBOFHNM_00201 2.1e-209 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NNBOFHNM_00202 5.8e-205 G PTS system Galactitol-specific IIC component
NNBOFHNM_00203 6.7e-72 K Bacterial regulatory proteins, tetR family
NNBOFHNM_00204 3.3e-129 yjjC V ATPases associated with a variety of cellular activities
NNBOFHNM_00205 1.1e-202 M Exporter of polyketide antibiotics
NNBOFHNM_00206 4e-100 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
NNBOFHNM_00207 2.3e-34 S Repeat protein
NNBOFHNM_00208 4.5e-277 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NNBOFHNM_00210 1.7e-15
NNBOFHNM_00213 5.9e-87 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NNBOFHNM_00214 2.1e-67 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
NNBOFHNM_00215 9.1e-43 yodB K Transcriptional regulator, HxlR family
NNBOFHNM_00216 7.4e-173 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NNBOFHNM_00217 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NNBOFHNM_00218 9.3e-129 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NNBOFHNM_00219 1.8e-97 udk 2.7.1.48 F Cytidine monophosphokinase
NNBOFHNM_00220 2.2e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NNBOFHNM_00221 6.4e-12
NNBOFHNM_00222 1.5e-143 iunH2 3.2.2.1 F nucleoside hydrolase
NNBOFHNM_00223 7.6e-43 XK27_03960 S Protein of unknown function (DUF3013)
NNBOFHNM_00224 5.8e-118 prmA J Ribosomal protein L11 methyltransferase
NNBOFHNM_00225 3.1e-77 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NNBOFHNM_00226 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NNBOFHNM_00227 1.7e-54 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NNBOFHNM_00228 6.7e-57 3.1.3.18 J HAD-hyrolase-like
NNBOFHNM_00229 5.2e-43 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NNBOFHNM_00230 7.3e-129 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NNBOFHNM_00231 1.3e-75 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NNBOFHNM_00232 2.7e-204 pyrP F Permease
NNBOFHNM_00233 4.3e-115 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NNBOFHNM_00234 5.9e-192 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NNBOFHNM_00235 1.5e-84 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NNBOFHNM_00236 2.3e-89 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NNBOFHNM_00237 9.8e-135 K Transcriptional regulator
NNBOFHNM_00238 6.3e-144 ppaC 3.6.1.1 C inorganic pyrophosphatase
NNBOFHNM_00239 8.6e-115 glcR K DeoR C terminal sensor domain
NNBOFHNM_00240 4.5e-171 patA 2.6.1.1 E Aminotransferase
NNBOFHNM_00241 2.4e-88 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NNBOFHNM_00243 1.1e-35 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NNBOFHNM_00244 2.7e-173 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NNBOFHNM_00245 1.8e-36 rnhA 3.1.26.4 L Ribonuclease HI
NNBOFHNM_00246 6.2e-21 S Family of unknown function (DUF5322)
NNBOFHNM_00247 3.8e-256 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NNBOFHNM_00248 1.8e-38
NNBOFHNM_00251 2.5e-149 EGP Sugar (and other) transporter
NNBOFHNM_00252 6e-78 trmK 2.1.1.217 S SAM-dependent methyltransferase
NNBOFHNM_00253 1.4e-102 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NNBOFHNM_00254 1.9e-183 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NNBOFHNM_00255 4.2e-73 alkD L DNA alkylation repair enzyme
NNBOFHNM_00256 3.8e-136 EG EamA-like transporter family
NNBOFHNM_00257 3.6e-150 S Tetratricopeptide repeat protein
NNBOFHNM_00258 6.9e-205 hisS 6.1.1.21 J histidyl-tRNA synthetase
NNBOFHNM_00259 4.3e-298 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NNBOFHNM_00260 7e-127 corA P CorA-like Mg2+ transporter protein
NNBOFHNM_00261 8.5e-161 nhaC C Na H antiporter NhaC
NNBOFHNM_00262 1.5e-130 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NNBOFHNM_00263 5.8e-81 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
NNBOFHNM_00265 7.2e-92 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NNBOFHNM_00266 2.9e-154 iscS 2.8.1.7 E Aminotransferase class V
NNBOFHNM_00267 3.7e-41 XK27_04120 S Putative amino acid metabolism
NNBOFHNM_00268 4.3e-203 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NNBOFHNM_00269 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NNBOFHNM_00270 4.3e-15 S Protein of unknown function (DUF2929)
NNBOFHNM_00271 0.0 dnaE 2.7.7.7 L DNA polymerase
NNBOFHNM_00272 1.9e-167 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NNBOFHNM_00273 6.3e-310 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NNBOFHNM_00275 1e-39 ypaA S Protein of unknown function (DUF1304)
NNBOFHNM_00276 3.2e-83 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NNBOFHNM_00277 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NNBOFHNM_00278 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NNBOFHNM_00279 1.2e-196 FbpA K Fibronectin-binding protein
NNBOFHNM_00280 3.1e-40 K Transcriptional regulator
NNBOFHNM_00281 2.2e-117 degV S EDD domain protein, DegV family
NNBOFHNM_00282 7.8e-71 lepB 3.4.21.89 U Signal peptidase, peptidase S26
NNBOFHNM_00283 2.4e-40 6.3.3.2 S ASCH
NNBOFHNM_00284 1.1e-186 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NNBOFHNM_00285 1.7e-79 yjjH S Calcineurin-like phosphoesterase
NNBOFHNM_00286 1.2e-91 EG EamA-like transporter family
NNBOFHNM_00287 2.3e-85 natB CP ABC-type Na efflux pump, permease component
NNBOFHNM_00288 6.2e-112 natA S Domain of unknown function (DUF4162)
NNBOFHNM_00289 4.8e-23 K Acetyltransferase (GNAT) domain
NNBOFHNM_00291 8.5e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NNBOFHNM_00292 4.5e-228 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NNBOFHNM_00293 2.7e-171 rpsA 1.17.7.4 J Ribosomal protein S1
NNBOFHNM_00294 9.1e-58 arsC 1.20.4.1 T Low molecular weight phosphatase family
NNBOFHNM_00295 2e-151 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NNBOFHNM_00296 4.9e-29 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNBOFHNM_00297 1.4e-175 dltB M MBOAT, membrane-bound O-acyltransferase family
NNBOFHNM_00298 4.5e-219 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNBOFHNM_00299 2.6e-07 dltX S D-Ala-teichoic acid biosynthesis protein
NNBOFHNM_00300 4.5e-90 recO L Involved in DNA repair and RecF pathway recombination
NNBOFHNM_00301 1e-154 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NNBOFHNM_00302 3.6e-30 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NNBOFHNM_00303 3e-60 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NNBOFHNM_00304 3.5e-153 phoH T phosphate starvation-inducible protein PhoH
NNBOFHNM_00305 7.5e-83 lytH 3.5.1.28 M Ami_3
NNBOFHNM_00306 2e-86 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NNBOFHNM_00307 5.9e-12 M Lysin motif
NNBOFHNM_00308 2e-128 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
NNBOFHNM_00309 7.1e-59 ypbB 5.1.3.1 S Helix-turn-helix domain
NNBOFHNM_00310 2.9e-221 mntH P H( )-stimulated, divalent metal cation uptake system
NNBOFHNM_00311 1.3e-44 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
NNBOFHNM_00312 7.1e-120 ica2 GT2 M Glycosyl transferase family group 2
NNBOFHNM_00313 4.8e-44
NNBOFHNM_00314 7.3e-79 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NNBOFHNM_00316 3e-36
NNBOFHNM_00317 9.8e-66 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NNBOFHNM_00318 4.2e-61 marR K Transcriptional regulator, MarR family
NNBOFHNM_00319 6.4e-102 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NNBOFHNM_00320 2.2e-27 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NNBOFHNM_00321 6.5e-104 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
NNBOFHNM_00322 1.4e-98 IQ reductase
NNBOFHNM_00323 1.8e-194 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NNBOFHNM_00324 8.7e-46 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NNBOFHNM_00325 1.5e-63 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NNBOFHNM_00326 9.3e-216 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
NNBOFHNM_00327 2.7e-125 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NNBOFHNM_00328 2.3e-102 accA 2.1.3.15, 6.4.1.2 I alpha subunit
NNBOFHNM_00329 5.5e-109 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NNBOFHNM_00330 1.5e-230 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NNBOFHNM_00331 3.1e-240 pgi 5.3.1.9 G Belongs to the GPI family
NNBOFHNM_00332 2.7e-302 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NNBOFHNM_00333 3.1e-117 gla U Major intrinsic protein
NNBOFHNM_00334 5.8e-45 ykuL S CBS domain
NNBOFHNM_00335 1.5e-60 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NNBOFHNM_00336 4.1e-177 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NNBOFHNM_00337 2.1e-88 ykuT M mechanosensitive ion channel
NNBOFHNM_00339 1e-285 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NNBOFHNM_00340 2e-21 yheA S Belongs to the UPF0342 family
NNBOFHNM_00341 5e-128 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
NNBOFHNM_00342 6.6e-114 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NNBOFHNM_00344 5.4e-53 hit FG histidine triad
NNBOFHNM_00345 2.8e-94 ecsA V ABC transporter, ATP-binding protein
NNBOFHNM_00346 1.3e-72 ecsB U ABC transporter
NNBOFHNM_00347 1.6e-98 ytmP 2.7.1.89 M Choline/ethanolamine kinase
NNBOFHNM_00348 7.9e-101 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NNBOFHNM_00349 4e-45 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NNBOFHNM_00350 6.8e-76 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NNBOFHNM_00351 9e-240 sftA D Belongs to the FtsK SpoIIIE SftA family
NNBOFHNM_00352 7.6e-223 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NNBOFHNM_00353 2.5e-61 phaJ I N-terminal half of MaoC dehydratase
NNBOFHNM_00354 8.8e-69 ybhL S Belongs to the BI1 family
NNBOFHNM_00355 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NNBOFHNM_00356 3.9e-108 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NNBOFHNM_00357 2.1e-50 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NNBOFHNM_00358 6.1e-66 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NNBOFHNM_00359 1.6e-79 dnaB L replication initiation and membrane attachment
NNBOFHNM_00360 2.2e-107 dnaI L Primosomal protein DnaI
NNBOFHNM_00361 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NNBOFHNM_00362 1.3e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NNBOFHNM_00363 2.9e-25 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NNBOFHNM_00364 7.7e-53 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NNBOFHNM_00365 2.5e-71 yqeG S HAD phosphatase, family IIIA
NNBOFHNM_00366 7.9e-181 yqeH S Ribosome biogenesis GTPase YqeH
NNBOFHNM_00367 1e-29 yhbY J RNA-binding protein
NNBOFHNM_00368 2.7e-77 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NNBOFHNM_00369 7.2e-72 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
NNBOFHNM_00370 1.5e-48 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NNBOFHNM_00371 4.2e-82 H Nodulation protein S (NodS)
NNBOFHNM_00372 1.3e-122 ylbM S Belongs to the UPF0348 family
NNBOFHNM_00373 2e-57 yceD S Uncharacterized ACR, COG1399
NNBOFHNM_00374 1.9e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NNBOFHNM_00375 1.2e-88 plsC 2.3.1.51 I Acyltransferase
NNBOFHNM_00376 1.1e-93 yabB 2.1.1.223 L Methyltransferase small domain
NNBOFHNM_00377 1.5e-27 yazA L GIY-YIG catalytic domain protein
NNBOFHNM_00378 1.9e-128 rpsB J Belongs to the universal ribosomal protein uS2 family
NNBOFHNM_00379 2.7e-128 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NNBOFHNM_00380 5.3e-37
NNBOFHNM_00381 3.4e-92 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NNBOFHNM_00382 4.1e-57 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NNBOFHNM_00383 3.8e-159 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NNBOFHNM_00384 2.7e-225 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NNBOFHNM_00385 2.5e-106 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NNBOFHNM_00387 3.1e-111 K response regulator
NNBOFHNM_00388 5e-167 arlS 2.7.13.3 T Histidine kinase
NNBOFHNM_00390 1.4e-69 rny D Peptidase family M23
NNBOFHNM_00391 3.3e-15 ganB 3.2.1.89 G arabinogalactan
NNBOFHNM_00392 9.8e-74 M transferase activity, transferring glycosyl groups
NNBOFHNM_00393 5.8e-57 cps3F
NNBOFHNM_00394 2e-160 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
NNBOFHNM_00395 3.7e-65 S Glycosyltransferase like family 2
NNBOFHNM_00396 1.6e-194 glf 5.4.99.9 M UDP-galactopyranose mutase
NNBOFHNM_00397 1.8e-95 M Core-2/I-Branching enzyme
NNBOFHNM_00398 2e-91 rfbP M Bacterial sugar transferase
NNBOFHNM_00399 1.8e-125 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NNBOFHNM_00400 1.6e-111 ywqE 3.1.3.48 GM PHP domain protein
NNBOFHNM_00401 9.3e-82 ywqD 2.7.10.1 D Capsular exopolysaccharide family
NNBOFHNM_00402 2.6e-77 epsB M biosynthesis protein
NNBOFHNM_00403 3.2e-214 ugd 1.1.1.22 M UDP binding domain
NNBOFHNM_00404 1e-42
NNBOFHNM_00405 3e-41 S Acyltransferase family
NNBOFHNM_00406 6.3e-130 S Membrane protein involved in the export of O-antigen and teichoic acid
NNBOFHNM_00407 5.8e-26 S Acetyltransferase (Isoleucine patch superfamily)
NNBOFHNM_00408 1.3e-42 M Glycosyltransferase like family 2
NNBOFHNM_00410 7.3e-46 S Glycosyl transferase family 2
NNBOFHNM_00411 8.9e-142 M Glycosyl transferase family 2
NNBOFHNM_00412 6.8e-47 2.3.1.79 S Hexapeptide repeat of succinyl-transferase
NNBOFHNM_00413 6.1e-23 G Glycosyltransferase Family 4
NNBOFHNM_00414 6.6e-85 G Glycosyltransferase Family 4
NNBOFHNM_00415 9.7e-174 rgpAc GT4 M Domain of unknown function (DUF1972)
NNBOFHNM_00417 2e-80 S response to antibiotic
NNBOFHNM_00418 9.8e-27 S zinc-ribbon domain
NNBOFHNM_00419 7.2e-118 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
NNBOFHNM_00420 9.9e-128 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NNBOFHNM_00421 6.2e-164 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NNBOFHNM_00422 4.2e-101 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NNBOFHNM_00423 1.2e-144 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NNBOFHNM_00424 1.3e-75 S Glycosyltransferase like family 2
NNBOFHNM_00425 2.5e-61 S Glycosyltransferase like family 2
NNBOFHNM_00426 2.6e-117 cps1D M Domain of unknown function (DUF4422)
NNBOFHNM_00427 3e-39 S CAAX protease self-immunity
NNBOFHNM_00428 1.2e-88 yvyE 3.4.13.9 S YigZ family
NNBOFHNM_00429 2.3e-58 S Haloacid dehalogenase-like hydrolase
NNBOFHNM_00430 2.9e-153 EGP Major facilitator Superfamily
NNBOFHNM_00432 5.3e-68 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NNBOFHNM_00433 1.2e-27 yraB K transcriptional regulator
NNBOFHNM_00434 9.8e-90 S NADPH-dependent FMN reductase
NNBOFHNM_00435 1e-102 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NNBOFHNM_00436 1.5e-55 S ECF transporter, substrate-specific component
NNBOFHNM_00437 2.5e-96 znuB U ABC 3 transport family
NNBOFHNM_00438 1e-98 fhuC P ABC transporter
NNBOFHNM_00439 1e-103 psaA P Belongs to the bacterial solute-binding protein 9 family
NNBOFHNM_00440 7.6e-38
NNBOFHNM_00441 6.5e-54 XK27_01040 S Protein of unknown function (DUF1129)
NNBOFHNM_00442 5.4e-190 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NNBOFHNM_00443 3.4e-23 yyzM S Bacterial protein of unknown function (DUF951)
NNBOFHNM_00444 1.8e-108 spo0J K Belongs to the ParB family
NNBOFHNM_00445 6.5e-118 soj D Sporulation initiation inhibitor
NNBOFHNM_00446 1.4e-81 noc K Belongs to the ParB family
NNBOFHNM_00447 1.5e-100 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
NNBOFHNM_00448 1.2e-126 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NNBOFHNM_00449 2.4e-109 3.1.4.46 C phosphodiesterase
NNBOFHNM_00450 0.0 pacL 3.6.3.8 P P-type ATPase
NNBOFHNM_00451 8.1e-136 tetA EGP Major facilitator Superfamily
NNBOFHNM_00452 1.8e-32 yvdC S MazG nucleotide pyrophosphohydrolase domain
NNBOFHNM_00453 2.5e-214 yjeM E Amino Acid
NNBOFHNM_00454 1.9e-190 glnPH2 P ABC transporter permease
NNBOFHNM_00455 2.3e-112 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NNBOFHNM_00456 6.3e-44 E GDSL-like Lipase/Acylhydrolase
NNBOFHNM_00457 1e-133 coaA 2.7.1.33 F Pantothenic acid kinase
NNBOFHNM_00458 1.3e-274 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NNBOFHNM_00459 3.3e-82
NNBOFHNM_00460 8.5e-34 S Predicted membrane protein (DUF2142)
NNBOFHNM_00461 5e-115 rfbJ M Glycosyl transferase family 2
NNBOFHNM_00462 2.1e-30 gtcA S Teichoic acid glycosylation protein
NNBOFHNM_00463 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NNBOFHNM_00464 1.2e-160 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NNBOFHNM_00465 4.7e-96 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NNBOFHNM_00466 5.4e-67 XK27_09620 S NADPH-dependent FMN reductase
NNBOFHNM_00467 2.7e-156 XK27_09615 S reductase
NNBOFHNM_00468 1.5e-39 2.7.7.65 T phosphorelay sensor kinase activity
NNBOFHNM_00469 3.3e-146 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
NNBOFHNM_00470 1.5e-55 S Psort location CytoplasmicMembrane, score
NNBOFHNM_00471 3.6e-14
NNBOFHNM_00472 2.9e-44 S Bacterial membrane protein, YfhO
NNBOFHNM_00473 8.5e-22 S Bacterial membrane protein, YfhO
NNBOFHNM_00474 8.8e-102 S Bacterial membrane protein, YfhO
NNBOFHNM_00475 3.2e-129 S Bacterial membrane protein YfhO
NNBOFHNM_00476 9.4e-07 XK27_08315 M Sulfatase
NNBOFHNM_00477 1.7e-145 XK27_08315 M Sulfatase
NNBOFHNM_00478 3.5e-82 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NNBOFHNM_00479 4.1e-177 thrC 4.2.3.1 E Threonine synthase
NNBOFHNM_00480 2.4e-128 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NNBOFHNM_00481 5.2e-168 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
NNBOFHNM_00482 5.6e-89 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NNBOFHNM_00483 5e-57 S peptidoglycan catabolic process
NNBOFHNM_00484 1.5e-194 XK27_08315 M Sulfatase
NNBOFHNM_00486 6.4e-168 mdtG EGP Major facilitator Superfamily
NNBOFHNM_00487 6.3e-251 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
NNBOFHNM_00488 5.7e-84 treR K UTRA
NNBOFHNM_00489 3.3e-259 treB G phosphotransferase system
NNBOFHNM_00490 3.5e-63 3.1.3.73 G phosphoglycerate mutase
NNBOFHNM_00491 2.4e-82 pncA Q isochorismatase
NNBOFHNM_00492 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
NNBOFHNM_00493 1.2e-103 ydhQ K UbiC transcription regulator-associated domain protein
NNBOFHNM_00494 2.9e-171 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NNBOFHNM_00495 3.6e-41 K Transcriptional regulator, HxlR family
NNBOFHNM_00496 8.3e-164 C Luciferase-like monooxygenase
NNBOFHNM_00497 3.6e-125 yvgN C Aldo keto reductase
NNBOFHNM_00498 8.8e-105 yraQ S Predicted permease
NNBOFHNM_00499 3.1e-62 yeeE S Sulphur transport
NNBOFHNM_00500 5.4e-17 yeeD O Belongs to the sulfur carrier protein TusA family
NNBOFHNM_00501 1.5e-115 ynjE 2.8.1.11 P Rhodanese Homology Domain
NNBOFHNM_00503 3.6e-234 prdA 1.21.4.1 EJ Glycine/sarcosine/betaine reductase component B subunits
NNBOFHNM_00504 2.1e-25 S Psort location Cytoplasmic, score
NNBOFHNM_00505 4.5e-66 prdB 1.21.4.1, 1.21.4.2 S the current gene model (or a revised gene model) may contain a premature stop
NNBOFHNM_00506 4.3e-31 S the current gene model (or a revised gene model) may contain a premature stop
NNBOFHNM_00507 6.8e-72 prdD S An automated process has identified a potential problem with this gene model
NNBOFHNM_00508 2.7e-66 3.5.1.1 EJ Glycine/sarcosine/betaine reductase component B subunits
NNBOFHNM_00509 7.8e-143 5.1.1.4 E Proline racemase
NNBOFHNM_00510 2.2e-93 XK27_00825 S Sulfite exporter TauE/SafE
NNBOFHNM_00511 4.1e-223 ybeC E amino acid
NNBOFHNM_00512 1.2e-48 yedF O Belongs to the sulfur carrier protein TusA family
NNBOFHNM_00513 2.9e-07 S Protein of unknown function (DUF3343)
NNBOFHNM_00514 4.8e-138 selB J Elongation factor SelB, winged helix
NNBOFHNM_00515 8.8e-111 sufS 2.8.1.7, 4.4.1.16 E Serine hydroxymethyltransferase
NNBOFHNM_00516 9.1e-110 selA 2.9.1.1 J Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis
NNBOFHNM_00517 6.9e-29 yitW S Iron-sulfur cluster assembly protein
NNBOFHNM_00518 3.4e-175 rnfC C RnfC Barrel sandwich hybrid domain
NNBOFHNM_00519 2.7e-100 selD 2.7.9.3 E Synthesizes selenophosphate from selenide and ATP
NNBOFHNM_00520 1.4e-148 yedE S Sulphur transport
NNBOFHNM_00521 1.2e-28 yedF O Belongs to the sulfur carrier protein TusA family
NNBOFHNM_00522 2.9e-16 2.7.1.194, 2.7.1.202 GKT COG3711 Transcriptional antiterminator
NNBOFHNM_00523 1.8e-57 yvbG U MarC family integral membrane protein
NNBOFHNM_00524 6.1e-181 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
NNBOFHNM_00525 1.9e-49 S Membrane
NNBOFHNM_00526 4.8e-76 rhaR K helix_turn_helix, arabinose operon control protein
NNBOFHNM_00527 1.5e-188 iolF EGP Major facilitator Superfamily
NNBOFHNM_00528 2.9e-215 rhaB 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NNBOFHNM_00529 4e-40 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
NNBOFHNM_00530 2.2e-219 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
NNBOFHNM_00531 1.5e-109 rhaD 4.1.2.17, 4.1.2.19 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
NNBOFHNM_00532 1.7e-19 S YjcQ protein
NNBOFHNM_00533 7.6e-105 L Belongs to the 'phage' integrase family
NNBOFHNM_00534 5.7e-23 3.1.21.3 V Type I restriction modification DNA specificity domain
NNBOFHNM_00535 8.6e-60 hsdM 2.1.1.72 V type I restriction-modification system
NNBOFHNM_00536 4.3e-26 K Cro/C1-type HTH DNA-binding domain
NNBOFHNM_00537 2.6e-80 S Putative inner membrane protein (DUF1819)
NNBOFHNM_00538 6.9e-69 S Domain of unknown function (DUF1788)
NNBOFHNM_00539 0.0 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
NNBOFHNM_00540 0.0 V restriction
NNBOFHNM_00541 4.4e-307 S TIGR02687 family
NNBOFHNM_00542 0.0 3.4.21.53 O Putative ATP-dependent Lon protease
NNBOFHNM_00543 8.4e-50
NNBOFHNM_00544 1.3e-37
NNBOFHNM_00545 1.5e-08
NNBOFHNM_00546 3.5e-16
NNBOFHNM_00547 5e-108 XK27_09655 S Virulence protein RhuM family
NNBOFHNM_00548 4.2e-21 M domain protein
NNBOFHNM_00549 3e-35 agrA KT Response regulator of the LytR AlgR family
NNBOFHNM_00550 6e-44 2.7.13.3 T protein histidine kinase activity
NNBOFHNM_00551 0.0 pepN 3.4.11.2 E aminopeptidase
NNBOFHNM_00552 2.9e-36
NNBOFHNM_00554 7.6e-125 D CobQ CobB MinD ParA nucleotide binding domain protein
NNBOFHNM_00555 6e-17 bglG K antiterminator
NNBOFHNM_00556 8.4e-91 2.7.1.193, 2.7.1.199, 2.7.1.208, 2.7.1.211 G .Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome down-regulated in Spo0A mutant
NNBOFHNM_00557 1.6e-37 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NNBOFHNM_00558 9.7e-128 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NNBOFHNM_00559 3.9e-38 S Replication initiator protein A (RepA) N-terminus
NNBOFHNM_00560 9.4e-109 L Initiator Replication protein
NNBOFHNM_00561 2.3e-07 G SMI1 / KNR4 family (SUKH-1)
NNBOFHNM_00563 3e-39 L PLD-like domain
NNBOFHNM_00564 1.4e-134 L PLD-like domain
NNBOFHNM_00565 6.5e-79 S Fic/DOC family
NNBOFHNM_00566 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
NNBOFHNM_00567 2.2e-60 K DeoR C terminal sensor domain
NNBOFHNM_00568 2.1e-39 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NNBOFHNM_00569 2e-35 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
NNBOFHNM_00570 2.4e-181 gatC G PTS system sugar-specific permease component
NNBOFHNM_00571 1.2e-119 gatD 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
NNBOFHNM_00572 5.3e-166 gutB 1.1.1.1, 1.1.1.14 E Dehydrogenase
NNBOFHNM_00573 2.3e-87 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NNBOFHNM_00574 5.2e-276 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NNBOFHNM_00575 7.6e-232 tetP J elongation factor G
NNBOFHNM_00576 1.6e-31 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NNBOFHNM_00578 1.5e-216 yjeM E Amino Acid
NNBOFHNM_00579 2.1e-58 yphA GM NAD dependent epimerase/dehydratase family
NNBOFHNM_00580 4.3e-75 K Helix-turn-helix domain, rpiR family
NNBOFHNM_00581 3.3e-92 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NNBOFHNM_00582 1.3e-127 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
NNBOFHNM_00583 6.5e-90 nanK GK ROK family
NNBOFHNM_00584 1.9e-53 ndk 2.7.4.6 F Belongs to the NDK family
NNBOFHNM_00585 6.1e-65 G Xylose isomerase domain protein TIM barrel
NNBOFHNM_00586 7.9e-155 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NNBOFHNM_00587 7.8e-208 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NNBOFHNM_00588 1.8e-62 sdaAB 4.3.1.17 E Serine dehydratase beta chain
NNBOFHNM_00589 1.4e-111 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NNBOFHNM_00590 7.7e-41 S Iron-sulfur cluster assembly protein
NNBOFHNM_00591 1.3e-66 S Protein of unknown function (DUF1440)
NNBOFHNM_00592 1.7e-81 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
NNBOFHNM_00593 5.9e-187 mtnE 2.6.1.83 E Aminotransferase
NNBOFHNM_00595 2.7e-15
NNBOFHNM_00596 1e-87 S Haloacid dehalogenase-like hydrolase
NNBOFHNM_00599 8.4e-71 xerD L Phage integrase, N-terminal SAM-like domain
NNBOFHNM_00600 3.1e-265 fbp 3.1.3.11 G phosphatase activity
NNBOFHNM_00602 1.3e-09 ycbI M COG0463 Glycosyltransferases involved in cell wall biogenesis
NNBOFHNM_00604 2.7e-52
NNBOFHNM_00605 2.3e-116 S Glycosyltransferase WbsX
NNBOFHNM_00606 3.5e-61 cps1B GT2,GT4 M Glycosyl transferases group 1
NNBOFHNM_00607 2.2e-104 cps2I S Psort location CytoplasmicMembrane, score
NNBOFHNM_00608 1.6e-146 lspL 5.1.3.6 GM RmlD substrate binding domain
NNBOFHNM_00609 3.7e-179 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NNBOFHNM_00610 3.4e-64 M Glycosyl transferases group 1
NNBOFHNM_00611 5.6e-126 M Glycosyl transferases group 1
NNBOFHNM_00614 3.4e-83 qorB 1.6.5.2 GM NmrA-like family
NNBOFHNM_00615 2.1e-39 K Transcriptional regulator
NNBOFHNM_00616 4.5e-30 S CHY zinc finger
NNBOFHNM_00617 5e-86 1.1.1.1 C Zinc-binding dehydrogenase
NNBOFHNM_00619 4.4e-41 S Protein of unknown function (DUF1211)
NNBOFHNM_00620 1.4e-25 ybl78 L Conserved phage C-terminus (Phg_2220_C)
NNBOFHNM_00622 2.5e-41 wecD M Acetyltransferase (GNAT) family
NNBOFHNM_00623 3.8e-75 cps2D 5.1.3.2 M RmlD substrate binding domain
NNBOFHNM_00624 1.2e-65 H Methyltransferase domain
NNBOFHNM_00626 1.3e-16 K DNA-templated transcription, initiation
NNBOFHNM_00628 2.2e-08 S Protein of unknown function (DUF2922)
NNBOFHNM_00631 8.3e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
NNBOFHNM_00632 1e-27 ysxB J Cysteine protease Prp
NNBOFHNM_00633 1.6e-42 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NNBOFHNM_00634 4.7e-09 M LysM domain
NNBOFHNM_00637 9.7e-73
NNBOFHNM_00638 1.2e-100 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
NNBOFHNM_00639 1.3e-178 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
NNBOFHNM_00640 2.3e-122 xerC D Belongs to the 'phage' integrase family. XerC subfamily
NNBOFHNM_00641 7e-79 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NNBOFHNM_00642 7.8e-218 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NNBOFHNM_00643 4.6e-37 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NNBOFHNM_00644 4.5e-58 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NNBOFHNM_00645 1.1e-56 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NNBOFHNM_00646 5.8e-100 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NNBOFHNM_00647 4.5e-58 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NNBOFHNM_00648 4.1e-51 yeaL S Protein of unknown function (DUF441)
NNBOFHNM_00649 4.8e-125 cvfB S S1 domain
NNBOFHNM_00650 7.3e-113 xerD D recombinase XerD
NNBOFHNM_00651 1.1e-293 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
NNBOFHNM_00652 1.8e-76 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NNBOFHNM_00653 4.4e-189 nhaC C Na H antiporter NhaC
NNBOFHNM_00654 1e-64 ypsA S Belongs to the UPF0398 family
NNBOFHNM_00655 4.6e-196 ade 3.5.4.2 F Adenine deaminase C-terminal domain
NNBOFHNM_00657 4.4e-74 2.3.1.178 M GNAT acetyltransferase
NNBOFHNM_00658 2.3e-68 maa 2.3.1.79 S Maltose acetyltransferase
NNBOFHNM_00659 2.8e-56 3.6.1.27 I Acid phosphatase homologues
NNBOFHNM_00660 4.9e-22 XK27_07525 3.6.1.55 F Hydrolase of X-linked nucleoside diphosphate N terminal
NNBOFHNM_00662 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
NNBOFHNM_00663 5.2e-202 hsdM 2.1.1.72 V type I restriction-modification system
NNBOFHNM_00664 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
NNBOFHNM_00665 1.5e-136 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NNBOFHNM_00666 2.1e-112 rssA S Phospholipase, patatin family
NNBOFHNM_00667 8.2e-16
NNBOFHNM_00668 1.5e-29
NNBOFHNM_00669 2.3e-79 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NNBOFHNM_00670 1.2e-99 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NNBOFHNM_00671 1.8e-08 K transcriptional
NNBOFHNM_00672 3.4e-10 S Protein of unknown function (DUF805)
NNBOFHNM_00675 1.5e-78 yvfR V ABC transporter
NNBOFHNM_00676 1.9e-53 yvfS V ABC-2 type transporter
NNBOFHNM_00677 5.4e-57 salK 2.7.13.3 T Histidine kinase
NNBOFHNM_00678 1.8e-75 desR K helix_turn_helix, Lux Regulon
NNBOFHNM_00679 1.4e-70 ptp3 3.1.3.48 T Tyrosine phosphatase family
NNBOFHNM_00680 1.6e-90 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
NNBOFHNM_00684 1.4e-142 xerS L Phage integrase family
NNBOFHNM_00685 3.8e-70 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NNBOFHNM_00686 2.5e-137 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NNBOFHNM_00687 9.5e-218 1.3.5.4 C FAD binding domain
NNBOFHNM_00688 1e-116 IQ Enoyl-(Acyl carrier protein) reductase
NNBOFHNM_00689 4.7e-138 G Xylose isomerase-like TIM barrel
NNBOFHNM_00690 3.7e-72 K Transcriptional regulator, LysR family
NNBOFHNM_00691 4.1e-98 EGP Major Facilitator Superfamily
NNBOFHNM_00692 2.6e-129 EGP Major Facilitator Superfamily
NNBOFHNM_00693 7e-35 L Integrase core domain
NNBOFHNM_00694 1.4e-41 L Integrase core domain
NNBOFHNM_00695 1.3e-20 L PFAM transposase IS3 IS911 family protein
NNBOFHNM_00696 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
NNBOFHNM_00697 1.7e-32 P Heavy-metal-associated domain
NNBOFHNM_00698 8.7e-31 tnp L Transposase IS66 family
NNBOFHNM_00699 1.7e-18 tnp
NNBOFHNM_00700 1.6e-43 L hmm pf00665
NNBOFHNM_00701 7.3e-124 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
NNBOFHNM_00702 4.6e-84 dps P Ferritin-like domain
NNBOFHNM_00703 1.1e-157 L transposase, IS605 OrfB family
NNBOFHNM_00704 2.5e-58 tlpA2 L Transposase IS200 like
NNBOFHNM_00705 4.1e-53 1.14.12.17 C Oxidoreductase NAD-binding domain
NNBOFHNM_00706 0.0 O Belongs to the peptidase S8 family
NNBOFHNM_00707 1e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NNBOFHNM_00708 3.1e-08
NNBOFHNM_00709 4.3e-09 yjaB_1 K Acetyltransferase (GNAT) domain
NNBOFHNM_00710 1.2e-15 yjaB_1 K Acetyltransferase (GNAT) domain
NNBOFHNM_00715 3.9e-10
NNBOFHNM_00716 3.8e-99 V domain protein
NNBOFHNM_00717 1.3e-119 xth 3.1.11.2 L exodeoxyribonuclease III
NNBOFHNM_00718 1.6e-17
NNBOFHNM_00719 1.1e-104 azlC E AzlC protein
NNBOFHNM_00720 1.3e-38 azlD S branched-chain amino acid
NNBOFHNM_00721 2.4e-65 I alpha/beta hydrolase fold
NNBOFHNM_00722 1.1e-25
NNBOFHNM_00723 1.2e-58 3.6.1.27 I phosphatase
NNBOFHNM_00724 5.4e-23
NNBOFHNM_00725 2.9e-93 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
NNBOFHNM_00726 8.3e-90 sirR K Helix-turn-helix diphteria tox regulatory element
NNBOFHNM_00727 3.1e-27 cspC K Cold shock protein
NNBOFHNM_00728 3.6e-81 thrE S Putative threonine/serine exporter
NNBOFHNM_00729 2.8e-49 S Threonine/Serine exporter, ThrE
NNBOFHNM_00730 3.2e-121 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NNBOFHNM_00731 4.9e-87 S Sucrose-6F-phosphate phosphohydrolase
NNBOFHNM_00732 1.9e-34 trxA O Belongs to the thioredoxin family
NNBOFHNM_00733 2.7e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NNBOFHNM_00734 2e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NNBOFHNM_00735 7.3e-65 degV S Uncharacterised protein, DegV family COG1307
NNBOFHNM_00737 4.3e-54 queT S QueT transporter
NNBOFHNM_00738 2.5e-33 XK27_01315 S Protein of unknown function (DUF2829)
NNBOFHNM_00739 5e-102 IQ Enoyl-(Acyl carrier protein) reductase
NNBOFHNM_00740 4.6e-112 argE 3.5.1.18 E Peptidase dimerisation domain
NNBOFHNM_00741 2.8e-173 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NNBOFHNM_00742 1.6e-94 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NNBOFHNM_00743 5e-87 S Alpha beta hydrolase
NNBOFHNM_00744 5.4e-44 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NNBOFHNM_00745 3.6e-140 V MatE
NNBOFHNM_00746 1.4e-156 gmuE 2.7.1.2, 2.7.1.4 GK ROK family
NNBOFHNM_00747 2.2e-63 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NNBOFHNM_00748 9.6e-97 V ABC transporter
NNBOFHNM_00749 9.6e-132 bacI V MacB-like periplasmic core domain
NNBOFHNM_00750 3.7e-75 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NNBOFHNM_00751 4.8e-26
NNBOFHNM_00752 1.9e-178 yhdP S Transporter associated domain
NNBOFHNM_00753 2.7e-79 ptp2 3.1.3.48 T Tyrosine phosphatase family
NNBOFHNM_00754 0.0 L Helicase C-terminal domain protein
NNBOFHNM_00755 9.6e-251 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NNBOFHNM_00756 8.8e-50 yugI 5.3.1.9 J general stress protein
NNBOFHNM_00757 2.7e-95 trxB2 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
NNBOFHNM_00758 3e-92 dedA S SNARE associated Golgi protein
NNBOFHNM_00759 7.8e-32 S Protein of unknown function (DUF1461)
NNBOFHNM_00760 2.9e-113 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NNBOFHNM_00761 1.9e-53 yutD S Protein of unknown function (DUF1027)
NNBOFHNM_00762 3e-57 S Calcineurin-like phosphoesterase
NNBOFHNM_00763 9.3e-184 cycA E Amino acid permease
NNBOFHNM_00764 9.9e-98 ytxK 2.1.1.72 L N-6 DNA Methylase
NNBOFHNM_00766 5.5e-11 S Putative Competence protein ComGF
NNBOFHNM_00768 1.5e-13
NNBOFHNM_00769 1.2e-27 comGC U competence protein ComGC
NNBOFHNM_00770 4.4e-98 comGB NU type II secretion system
NNBOFHNM_00771 4.7e-121 comGA NU Type II IV secretion system protein
NNBOFHNM_00772 2.1e-102 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NNBOFHNM_00773 1.5e-119 yebC K Transcriptional regulatory protein
NNBOFHNM_00774 3.7e-42 S VanZ like family
NNBOFHNM_00775 1.3e-158 ccpA K catabolite control protein A
NNBOFHNM_00776 1e-172 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NNBOFHNM_00777 1.5e-13
NNBOFHNM_00780 5.9e-75 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NNBOFHNM_00781 7.1e-35 K helix_turn_helix, Arsenical Resistance Operon Repressor
NNBOFHNM_00782 5.2e-65 hly S protein, hemolysin III
NNBOFHNM_00783 7.3e-41 M1-874 K Domain of unknown function (DUF1836)
NNBOFHNM_00784 9.4e-84 S membrane
NNBOFHNM_00785 1.1e-79 S VIT family
NNBOFHNM_00786 1.8e-148 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
NNBOFHNM_00787 7.9e-56 P Plays a role in the regulation of phosphate uptake
NNBOFHNM_00788 1.8e-115 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NNBOFHNM_00789 9.1e-115 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NNBOFHNM_00790 3e-122 pstA P Phosphate transport system permease protein PstA
NNBOFHNM_00791 4.1e-119 pstC P probably responsible for the translocation of the substrate across the membrane
NNBOFHNM_00792 3.2e-97 pstS P Phosphate
NNBOFHNM_00793 1.3e-41 yjbH Q Thioredoxin
NNBOFHNM_00794 1.5e-232 pepF E oligoendopeptidase F
NNBOFHNM_00795 1.1e-68 coiA 3.6.4.12 S Competence protein
NNBOFHNM_00796 2.1e-47 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NNBOFHNM_00797 1.4e-218 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
NNBOFHNM_00799 0.0 L MobA MobL family protein
NNBOFHNM_00800 4.8e-23
NNBOFHNM_00801 4e-41
NNBOFHNM_00802 3.4e-126 S protein conserved in bacteria
NNBOFHNM_00803 8.3e-27
NNBOFHNM_00804 4.3e-43 relB L Addiction module antitoxin, RelB DinJ family
NNBOFHNM_00805 6.8e-137 S Fic/DOC family
NNBOFHNM_00806 4.9e-25
NNBOFHNM_00807 1.1e-132 repA S Replication initiator protein A
NNBOFHNM_00808 9.7e-22
NNBOFHNM_00809 1.4e-147 D CobQ CobB MinD ParA nucleotide binding domain protein
NNBOFHNM_00810 2.8e-28 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
NNBOFHNM_00811 8.2e-36 alkD L DNA alkylation repair enzyme
NNBOFHNM_00812 2.4e-29 alkD L DNA alkylation repair enzyme
NNBOFHNM_00813 1.4e-52 K Psort location Cytoplasmic, score
NNBOFHNM_00814 4.9e-51 yjdF S Protein of unknown function (DUF2992)
NNBOFHNM_00815 1.1e-19 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
NNBOFHNM_00816 1.4e-47 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
NNBOFHNM_00823 1.6e-45
NNBOFHNM_00824 7.1e-34 S RelB antitoxin
NNBOFHNM_00825 9.4e-101
NNBOFHNM_00826 2.8e-87
NNBOFHNM_00827 1.8e-130 3.6.1.13, 3.6.1.55 F NUDIX domain
NNBOFHNM_00828 4e-270 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NNBOFHNM_00829 5e-104 pncA Q Isochorismatase family
NNBOFHNM_00830 1.2e-25
NNBOFHNM_00831 6.5e-102 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
NNBOFHNM_00832 2.6e-247 gshR 1.8.1.7 C Glutathione reductase
NNBOFHNM_00833 4.9e-179 proV E ABC transporter, ATP-binding protein
NNBOFHNM_00834 7e-273 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NNBOFHNM_00835 1.2e-79 cbiO2 P ABC transporter
NNBOFHNM_00836 3.4e-56 cbiO2 P ABC transporter
NNBOFHNM_00837 2.1e-157 P ABC transporter
NNBOFHNM_00838 1.1e-133 cbiQ P Cobalt transport protein
NNBOFHNM_00839 7.7e-90 2.7.7.65 T phosphorelay sensor kinase activity
NNBOFHNM_00840 1.6e-197 dtpT U amino acid peptide transporter
NNBOFHNM_00841 1.1e-07
NNBOFHNM_00843 2.7e-90 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NNBOFHNM_00844 4.9e-96 gntR1 K UbiC transcription regulator-associated domain protein
NNBOFHNM_00845 2.5e-90 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NNBOFHNM_00846 3.3e-243 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NNBOFHNM_00847 1e-129 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NNBOFHNM_00848 8.2e-251 yhgF K Tex-like protein N-terminal domain protein
NNBOFHNM_00849 7.2e-45 ydcK S Belongs to the SprT family
NNBOFHNM_00851 1.3e-115 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NNBOFHNM_00852 5.9e-129 mleP2 S Sodium Bile acid symporter family
NNBOFHNM_00853 4.9e-85 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NNBOFHNM_00854 1e-33 S Enterocin A Immunity
NNBOFHNM_00855 7.6e-223 pepC 3.4.22.40 E Peptidase C1-like family
NNBOFHNM_00856 4.3e-19 HA62_12640 S GCN5-related N-acetyl-transferase
NNBOFHNM_00857 4e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
NNBOFHNM_00858 5.4e-224 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NNBOFHNM_00859 8.2e-154 yacL S domain protein
NNBOFHNM_00860 2.9e-247 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NNBOFHNM_00861 2.4e-206 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NNBOFHNM_00862 6.4e-56 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NNBOFHNM_00863 3.2e-109 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NNBOFHNM_00864 5.4e-71 yacP S YacP-like NYN domain
NNBOFHNM_00865 2.1e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NNBOFHNM_00866 9.9e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NNBOFHNM_00867 7.7e-84 nusG K Participates in transcription elongation, termination and antitermination
NNBOFHNM_00868 5e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NNBOFHNM_00869 1.6e-115 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NNBOFHNM_00870 7.6e-75 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NNBOFHNM_00871 2.6e-48 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NNBOFHNM_00872 1.4e-54
NNBOFHNM_00873 1.6e-301 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NNBOFHNM_00874 1e-160 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NNBOFHNM_00875 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NNBOFHNM_00876 4.8e-45 nrdI F NrdI Flavodoxin like
NNBOFHNM_00877 1.2e-27 nrdH O Glutaredoxin
NNBOFHNM_00878 1.1e-75 rsmC 2.1.1.172 J Methyltransferase
NNBOFHNM_00879 3.3e-62 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NNBOFHNM_00880 4.3e-210 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NNBOFHNM_00881 7e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NNBOFHNM_00882 2.2e-97 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NNBOFHNM_00883 1.4e-65 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NNBOFHNM_00884 3e-83 holB 2.7.7.7 L DNA polymerase III
NNBOFHNM_00885 1.4e-40 yabA L Involved in initiation control of chromosome replication
NNBOFHNM_00886 4.1e-92 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NNBOFHNM_00887 4.7e-81 fat 3.1.2.21 I Acyl-ACP thioesterase
NNBOFHNM_00888 3.5e-140 ansA 3.5.1.1 EJ Asparaginase
NNBOFHNM_00889 3.7e-70 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
NNBOFHNM_00890 4.3e-28 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
NNBOFHNM_00891 8.4e-161 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NNBOFHNM_00892 6.9e-257 uup S ABC transporter, ATP-binding protein
NNBOFHNM_00893 2.8e-98 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NNBOFHNM_00894 1.4e-33 S CAAX protease self-immunity
NNBOFHNM_00895 2.4e-33 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NNBOFHNM_00896 1.3e-272 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NNBOFHNM_00897 2.5e-269 aha1 P COG COG0474 Cation transport ATPase
NNBOFHNM_00898 3.5e-295 ydaO E amino acid
NNBOFHNM_00899 1.6e-157 tagO 2.7.8.33, 2.7.8.35 M transferase
NNBOFHNM_00900 3.2e-128 comFA L Helicase C-terminal domain protein
NNBOFHNM_00901 5.6e-44 comFC S Competence protein
NNBOFHNM_00902 6e-81 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NNBOFHNM_00903 7e-95 yeaN P Major Facilitator Superfamily
NNBOFHNM_00904 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NNBOFHNM_00905 2.2e-164 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NNBOFHNM_00906 9.1e-68 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
NNBOFHNM_00907 6e-86 K response regulator
NNBOFHNM_00908 1.2e-85 phoR 2.7.13.3 T Histidine kinase
NNBOFHNM_00909 2.4e-08 pspC KT PspC domain
NNBOFHNM_00910 1.6e-26 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
NNBOFHNM_00911 8.7e-133 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NNBOFHNM_00912 1.1e-112 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NNBOFHNM_00913 6.1e-273 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NNBOFHNM_00914 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NNBOFHNM_00915 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NNBOFHNM_00916 1.1e-83 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NNBOFHNM_00917 5e-79 ylbE GM NAD dependent epimerase dehydratase family protein
NNBOFHNM_00918 7.5e-126 rapZ S Displays ATPase and GTPase activities
NNBOFHNM_00919 8.2e-153 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NNBOFHNM_00920 1.8e-149 whiA K May be required for sporulation
NNBOFHNM_00921 1.1e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NNBOFHNM_00923 3.2e-136 cggR K Putative sugar-binding domain
NNBOFHNM_00924 1.3e-179 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NNBOFHNM_00925 3.2e-201 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NNBOFHNM_00926 2.3e-128 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NNBOFHNM_00927 9.5e-234 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NNBOFHNM_00928 3.2e-131 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NNBOFHNM_00929 5e-104 K response regulator
NNBOFHNM_00930 1.8e-169 T PhoQ Sensor
NNBOFHNM_00931 6.7e-146 lmrP E Major Facilitator Superfamily
NNBOFHNM_00932 1.2e-179 clcA P chloride
NNBOFHNM_00933 2.8e-19 secG U Preprotein translocase
NNBOFHNM_00934 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NNBOFHNM_00935 6.9e-70 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NNBOFHNM_00936 9.1e-42 yxjI
NNBOFHNM_00937 2.4e-116 ycsE S Sucrose-6F-phosphate phosphohydrolase
NNBOFHNM_00938 5.2e-106 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NNBOFHNM_00939 2e-143 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NNBOFHNM_00940 3.2e-56 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
NNBOFHNM_00941 1.9e-68 dnaQ 2.7.7.7 L DNA polymerase III
NNBOFHNM_00942 3.5e-115 murB 1.3.1.98 M Cell wall formation
NNBOFHNM_00943 2.4e-71 S Protein of unknown function (DUF1361)
NNBOFHNM_00944 8.5e-127 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NNBOFHNM_00945 5.3e-68 ybbR S YbbR-like protein
NNBOFHNM_00946 2.6e-226 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NNBOFHNM_00947 7.5e-29 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
NNBOFHNM_00948 5.3e-131 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
NNBOFHNM_00949 3.2e-21 cutC P Participates in the control of copper homeostasis
NNBOFHNM_00950 9e-197 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NNBOFHNM_00951 5.9e-164 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NNBOFHNM_00952 4.9e-61 ybaK J Aminoacyl-tRNA editing domain
NNBOFHNM_00953 1.7e-98 rrmA 2.1.1.187 H Methyltransferase
NNBOFHNM_00954 4.4e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NNBOFHNM_00955 1.6e-281 ftsK D Belongs to the FtsK SpoIIIE SftA family
NNBOFHNM_00956 5.5e-97 ymfF S Peptidase M16 inactive domain protein
NNBOFHNM_00957 8.7e-147 ymfH S Peptidase M16
NNBOFHNM_00958 8.4e-91 IQ Enoyl-(Acyl carrier protein) reductase
NNBOFHNM_00959 2.9e-64 ymfM S Helix-turn-helix domain
NNBOFHNM_00960 2.8e-84 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NNBOFHNM_00961 2.3e-159 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NNBOFHNM_00962 5.9e-182 rny S Endoribonuclease that initiates mRNA decay
NNBOFHNM_00963 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NNBOFHNM_00964 6e-224 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NNBOFHNM_00965 7.3e-72 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NNBOFHNM_00966 6.3e-153 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NNBOFHNM_00967 2.1e-183 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NNBOFHNM_00968 2.9e-207 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NNBOFHNM_00969 1.8e-12 yajC U Preprotein translocase
NNBOFHNM_00971 4.3e-61 uspA T universal stress protein
NNBOFHNM_00973 2e-208 yfnA E Amino Acid
NNBOFHNM_00974 6.9e-117 lutA C Cysteine-rich domain
NNBOFHNM_00975 2.1e-245 lutB C 4Fe-4S dicluster domain
NNBOFHNM_00976 1.9e-66 yrjD S LUD domain
NNBOFHNM_00977 1e-146 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NNBOFHNM_00978 7.5e-13
NNBOFHNM_00979 2.7e-121 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
NNBOFHNM_00980 6.7e-187 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NNBOFHNM_00981 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NNBOFHNM_00982 2.1e-36 yrzL S Belongs to the UPF0297 family
NNBOFHNM_00983 2.3e-59 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NNBOFHNM_00984 1.9e-33 yrzB S Belongs to the UPF0473 family
NNBOFHNM_00985 1.4e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NNBOFHNM_00986 9.5e-18 cvpA S Colicin V production protein
NNBOFHNM_00987 3.9e-310 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NNBOFHNM_00988 9.9e-41 trxA O Belongs to the thioredoxin family
NNBOFHNM_00989 1.1e-60 yslB S Protein of unknown function (DUF2507)
NNBOFHNM_00990 2.2e-73 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NNBOFHNM_00991 5.1e-42 S Phosphoesterase
NNBOFHNM_00994 1.2e-140 hprA 1.1.1.29 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NNBOFHNM_00995 2.8e-305 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NNBOFHNM_00996 2.2e-214 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NNBOFHNM_00997 4.8e-199 oatA I Acyltransferase
NNBOFHNM_00998 1.4e-16
NNBOFHNM_01000 8.9e-141 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NNBOFHNM_01001 6.5e-100 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
NNBOFHNM_01002 4e-219 recJ L Single-stranded-DNA-specific exonuclease RecJ
NNBOFHNM_01003 1.3e-80 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NNBOFHNM_01004 3.5e-296 S membrane
NNBOFHNM_01005 1.5e-278 pbp2b 3.4.16.4 M Penicillin-binding Protein
NNBOFHNM_01006 1.8e-27 S Protein of unknown function (DUF3290)
NNBOFHNM_01007 3.3e-75 yviA S Protein of unknown function (DUF421)
NNBOFHNM_01009 4.5e-125 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NNBOFHNM_01010 7.7e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NNBOFHNM_01011 1.1e-53 tag 3.2.2.20 L glycosylase
NNBOFHNM_01012 6e-72 usp6 T universal stress protein
NNBOFHNM_01014 5.1e-184 rarA L recombination factor protein RarA
NNBOFHNM_01015 3.4e-24 yueI S Protein of unknown function (DUF1694)
NNBOFHNM_01016 7.5e-101 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NNBOFHNM_01017 4.2e-56 ytsP 1.8.4.14 T GAF domain-containing protein
NNBOFHNM_01018 5.8e-175 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NNBOFHNM_01019 6.4e-162 iscS2 2.8.1.7 E Aminotransferase class V
NNBOFHNM_01020 1.9e-196 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NNBOFHNM_01021 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NNBOFHNM_01022 3.7e-137 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NNBOFHNM_01023 8.1e-80 radC L DNA repair protein
NNBOFHNM_01024 4.5e-21 K Cold shock
NNBOFHNM_01025 3.6e-156 mreB D cell shape determining protein MreB
NNBOFHNM_01026 2.1e-88 mreC M Involved in formation and maintenance of cell shape
NNBOFHNM_01027 2e-54 mreD M rod shape-determining protein MreD
NNBOFHNM_01028 8.3e-77 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NNBOFHNM_01029 6.8e-126 minD D Belongs to the ParA family
NNBOFHNM_01030 1.9e-94 glnP P ABC transporter permease
NNBOFHNM_01031 1.8e-89 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NNBOFHNM_01032 3.7e-109 aatB ET ABC transporter substrate-binding protein
NNBOFHNM_01033 9.8e-100 D Alpha beta
NNBOFHNM_01035 1.2e-155 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
NNBOFHNM_01036 2.2e-07 S Protein of unknown function (DUF3397)
NNBOFHNM_01037 1.5e-55 mraZ K Belongs to the MraZ family
NNBOFHNM_01038 4e-141 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NNBOFHNM_01039 2.5e-11 ftsL D cell division protein FtsL
NNBOFHNM_01040 4e-282 ftsI 3.4.16.4 M Penicillin-binding Protein
NNBOFHNM_01041 8.7e-136 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NNBOFHNM_01042 2.2e-185 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NNBOFHNM_01043 1.8e-153 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NNBOFHNM_01044 1.3e-61 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NNBOFHNM_01045 5.2e-190 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NNBOFHNM_01046 9.8e-180 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NNBOFHNM_01047 5e-33 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NNBOFHNM_01048 3e-19 yggT S YGGT family
NNBOFHNM_01049 1.7e-81 ylmH S S4 domain protein
NNBOFHNM_01050 8.6e-62 divIVA D DivIVA domain protein
NNBOFHNM_01051 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NNBOFHNM_01052 2.5e-102 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NNBOFHNM_01053 4.4e-74 draG O ADP-ribosylglycohydrolase
NNBOFHNM_01055 5.7e-85 2.7.7.12 C Domain of unknown function (DUF4931)
NNBOFHNM_01056 1.4e-92 T Calcineurin-like phosphoesterase superfamily domain
NNBOFHNM_01057 5.5e-49 lytE M LysM domain protein
NNBOFHNM_01058 5e-19 glpE P Rhodanese Homology Domain
NNBOFHNM_01059 2.4e-27 xlyB 3.5.1.28 CBM50 M LysM domain
NNBOFHNM_01060 6.9e-160 asnA 6.3.1.1 F aspartate--ammonia ligase
NNBOFHNM_01061 7.9e-194 cydA 1.10.3.14 C ubiquinol oxidase
NNBOFHNM_01062 2.5e-141 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
NNBOFHNM_01063 2.7e-204 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NNBOFHNM_01064 3.6e-220 cydD CO ABC transporter transmembrane region
NNBOFHNM_01065 1.1e-96 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NNBOFHNM_01066 1.5e-105 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
NNBOFHNM_01067 6.6e-157 ndh 1.6.99.3 C NADH dehydrogenase
NNBOFHNM_01068 1.5e-146 pbuO_1 S Permease family
NNBOFHNM_01070 2.4e-32 2.7.7.65 T GGDEF domain
NNBOFHNM_01071 1.7e-129 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
NNBOFHNM_01072 6.5e-183
NNBOFHNM_01073 5.8e-206 S Protein conserved in bacteria
NNBOFHNM_01074 1.2e-201 ydaM M Glycosyl transferase family group 2
NNBOFHNM_01075 0.0 ydaN S Bacterial cellulose synthase subunit
NNBOFHNM_01076 2.4e-113 2.7.7.65 T diguanylate cyclase activity
NNBOFHNM_01077 1.7e-38 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
NNBOFHNM_01078 1.9e-50 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
NNBOFHNM_01079 6.9e-309 L Helicase C-terminal domain protein
NNBOFHNM_01080 0.0 rafA 3.2.1.22 G alpha-galactosidase
NNBOFHNM_01081 8.9e-54 S Membrane
NNBOFHNM_01082 3.5e-64 K helix_turn_helix, arabinose operon control protein
NNBOFHNM_01083 2.3e-45
NNBOFHNM_01084 1.3e-204 pipD E Dipeptidase
NNBOFHNM_01085 1.1e-23 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NNBOFHNM_01086 2e-191 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NNBOFHNM_01087 4.5e-60 speG J Acetyltransferase (GNAT) domain
NNBOFHNM_01088 2.3e-113 yitU 3.1.3.104 S hydrolase
NNBOFHNM_01089 1.6e-79 yjfP S COG1073 Hydrolases of the alpha beta superfamily
NNBOFHNM_01090 4.8e-81
NNBOFHNM_01091 2e-178 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
NNBOFHNM_01092 6.7e-42 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
NNBOFHNM_01093 1.4e-48 cps4C M Chain length determinant protein
NNBOFHNM_01094 9.4e-65 cpsD D AAA domain
NNBOFHNM_01095 4.4e-207 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 M Psort location CytoplasmicMembrane, score
NNBOFHNM_01096 9.1e-167 2.6.1.102 M Belongs to the DegT DnrJ EryC1 family
NNBOFHNM_01097 4.8e-77 epsL M Bacterial sugar transferase
NNBOFHNM_01098 2.2e-25 pglD 2.3.1.203 S Bacterial transferase hexapeptide (six repeats)
NNBOFHNM_01099 5.3e-121 2.4.1.52 GT4 M Glycosyl transferases group 1
NNBOFHNM_01100 1.8e-79 gtf1 2.4.1.52 GT4 M glycosyl transferase group 1
NNBOFHNM_01101 6.8e-76 M Glycosyltransferase Family 4
NNBOFHNM_01102 1e-42 GT2 V Glycosyl transferase, family 2
NNBOFHNM_01103 5.1e-40 pglI 2.4.1.293 GT2 M Glycosyltransferase like family 2
NNBOFHNM_01104 4.8e-190 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NNBOFHNM_01105 1.9e-243 lysP E amino acid
NNBOFHNM_01106 2.3e-69 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
NNBOFHNM_01107 3.3e-271 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NNBOFHNM_01108 3.2e-14 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NNBOFHNM_01109 7.2e-57 lssY 3.6.1.27 I phosphatidate phosphatase activity
NNBOFHNM_01110 1.7e-82 lysR5 K LysR substrate binding domain
NNBOFHNM_01111 6.5e-119 yxaA S membrane transporter protein
NNBOFHNM_01112 2.6e-32 ywjH S Protein of unknown function (DUF1634)
NNBOFHNM_01113 4.1e-126 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NNBOFHNM_01114 1.7e-225 pipD E Dipeptidase
NNBOFHNM_01115 2.3e-21 K helix_turn_helix multiple antibiotic resistance protein
NNBOFHNM_01116 8.8e-166 EGP Major facilitator Superfamily
NNBOFHNM_01117 5.6e-82 S L,D-transpeptidase catalytic domain
NNBOFHNM_01118 3.5e-141 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NNBOFHNM_01119 1.5e-144 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NNBOFHNM_01120 7.2e-27 ydiI Q Thioesterase superfamily
NNBOFHNM_01121 1.2e-56 yfeJ 6.3.5.2 F glutamine amidotransferase
NNBOFHNM_01122 1.1e-148 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
NNBOFHNM_01123 6.4e-114 degV S EDD domain protein, DegV family
NNBOFHNM_01124 5.2e-129 cadA P P-type ATPase
NNBOFHNM_01125 8.4e-76 cadA P P-type ATPase
NNBOFHNM_01126 1.8e-254 E Amino acid permease
NNBOFHNM_01127 3.3e-74 S Membrane
NNBOFHNM_01129 9.1e-50 cps3F
NNBOFHNM_01130 1.2e-145 Q Imidazolonepropionase and related amidohydrolases
NNBOFHNM_01131 1e-149 E glutamate:sodium symporter activity
NNBOFHNM_01132 5.5e-144 dapE 3.5.1.18 E Peptidase dimerisation domain
NNBOFHNM_01137 4.2e-145 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NNBOFHNM_01138 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NNBOFHNM_01139 1.3e-279 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NNBOFHNM_01140 9.3e-161 camS S sex pheromone
NNBOFHNM_01141 7.6e-38 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NNBOFHNM_01142 4e-233 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NNBOFHNM_01143 2.8e-255 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NNBOFHNM_01144 6.4e-145 yegS 2.7.1.107 G Lipid kinase
NNBOFHNM_01145 1.1e-208 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NNBOFHNM_01146 7e-121 L Mrr N-terminal domain
NNBOFHNM_01147 1.3e-17
NNBOFHNM_01148 1.3e-75 K phage regulatory protein, rha family
NNBOFHNM_01149 3e-22
NNBOFHNM_01150 4.1e-16
NNBOFHNM_01151 1.6e-65 L AAA domain
NNBOFHNM_01152 5.4e-19 K Cro/C1-type HTH DNA-binding domain
NNBOFHNM_01153 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
NNBOFHNM_01154 1.3e-162 hsdM 2.1.1.72 V cog cog0286
NNBOFHNM_01155 3.2e-37 hsdM 2.1.1.72 V type I restriction-modification system
NNBOFHNM_01156 5.4e-48 3.1.21.3 V Type I restriction modification DNA specificity domain
NNBOFHNM_01164 2.4e-130 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NNBOFHNM_01165 1.4e-186 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NNBOFHNM_01166 3.7e-159 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NNBOFHNM_01167 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NNBOFHNM_01168 2.5e-119 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NNBOFHNM_01170 1.6e-55 ctsR K Belongs to the CtsR family
NNBOFHNM_01171 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NNBOFHNM_01172 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NNBOFHNM_01173 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NNBOFHNM_01174 3.3e-23 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
NNBOFHNM_01175 6.1e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NNBOFHNM_01176 2.1e-71 L PFAM transposase IS200-family protein
NNBOFHNM_01177 4.9e-217 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NNBOFHNM_01178 7.2e-149 mepA V MATE efflux family protein
NNBOFHNM_01179 4.3e-150 lsa S ABC transporter
NNBOFHNM_01180 5.2e-83 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NNBOFHNM_01181 8e-110 puuD S peptidase C26
NNBOFHNM_01182 2.2e-201 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
NNBOFHNM_01183 1.1e-25
NNBOFHNM_01184 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
NNBOFHNM_01185 6.6e-60 uspA T Universal stress protein family
NNBOFHNM_01187 2.5e-211 glnP P ABC transporter
NNBOFHNM_01188 1.9e-168 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NNBOFHNM_01196 2.1e-07
NNBOFHNM_01213 7.4e-177 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NNBOFHNM_01214 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NNBOFHNM_01215 9.7e-194 cycA E Amino acid permease
NNBOFHNM_01216 8.3e-187 ytgP S Polysaccharide biosynthesis protein
NNBOFHNM_01217 1.1e-61 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NNBOFHNM_01218 1.2e-80 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NNBOFHNM_01219 5.1e-193 pepV 3.5.1.18 E dipeptidase PepV
NNBOFHNM_01220 3.3e-182 S Protein of unknown function DUF262
NNBOFHNM_01221 4.6e-08 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NNBOFHNM_01223 2.8e-186 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NNBOFHNM_01224 1.4e-211 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NNBOFHNM_01225 8.1e-280 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NNBOFHNM_01226 3.7e-168 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NNBOFHNM_01227 3.3e-117 EGP Major Facilitator Superfamily
NNBOFHNM_01228 1.2e-123 akr5f 1.1.1.346 S reductase
NNBOFHNM_01229 2.7e-72 K Transcriptional regulator
NNBOFHNM_01230 9.9e-110 pepE 3.4.13.21 E Alpha/beta hydrolase of unknown function (DUF915)
NNBOFHNM_01231 5.5e-69 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NNBOFHNM_01232 6.3e-20
NNBOFHNM_01235 2.8e-167 potE2 E amino acid
NNBOFHNM_01236 2.1e-146 ald 1.4.1.1 C Belongs to the AlaDH PNT family
NNBOFHNM_01237 6.7e-115 queH 1.17.99.6, 3.1.26.4 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NNBOFHNM_01238 2.8e-56 racA K Domain of unknown function (DUF1836)
NNBOFHNM_01239 3.8e-79 yitS S EDD domain protein, DegV family
NNBOFHNM_01240 5.3e-35 S virion core protein, lumpy skin disease virus
NNBOFHNM_01242 2.1e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NNBOFHNM_01243 1.3e-173 malY 4.4.1.8 E Aminotransferase, class I
NNBOFHNM_01244 5.3e-118 K AI-2E family transporter
NNBOFHNM_01245 4e-61 EG EamA-like transporter family
NNBOFHNM_01246 3.9e-76 L haloacid dehalogenase-like hydrolase
NNBOFHNM_01247 5.8e-117 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NNBOFHNM_01248 8.7e-67 1.5.1.38 S NADPH-dependent FMN reductase
NNBOFHNM_01249 9.1e-76 cylA V abc transporter atp-binding protein
NNBOFHNM_01250 2.6e-59 cylB V ABC-2 type transporter
NNBOFHNM_01251 4.1e-27 K LytTr DNA-binding domain
NNBOFHNM_01252 4.8e-11 S Protein of unknown function (DUF3021)
NNBOFHNM_01253 1.6e-154 L Transposase
NNBOFHNM_01254 1.1e-10 L Transposase
NNBOFHNM_01255 4.6e-79
NNBOFHNM_01256 3.9e-259 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
NNBOFHNM_01257 7.8e-211 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NNBOFHNM_01258 1.3e-91 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NNBOFHNM_01259 1.2e-89 patB 4.4.1.8 E Aminotransferase, class I
NNBOFHNM_01260 2.5e-113 K response regulator
NNBOFHNM_01261 3.3e-142 hpk31 2.7.13.3 T Histidine kinase
NNBOFHNM_01262 2.2e-90 lacX 5.1.3.3 G Aldose 1-epimerase
NNBOFHNM_01263 1.9e-20 G Transporter, major facilitator family protein
NNBOFHNM_01264 4.3e-116 G Transporter, major facilitator family protein
NNBOFHNM_01265 8e-62 yvdD 3.2.2.10 S Possible lysine decarboxylase
NNBOFHNM_01266 1.8e-72 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
NNBOFHNM_01268 2.3e-63 srtA 3.4.22.70 M sortase family
NNBOFHNM_01269 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NNBOFHNM_01270 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NNBOFHNM_01271 1.1e-33
NNBOFHNM_01272 1.8e-141 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NNBOFHNM_01273 1e-157 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NNBOFHNM_01274 1.5e-96 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NNBOFHNM_01275 4.7e-158 manA 5.3.1.8 G mannose-6-phosphate isomerase
NNBOFHNM_01276 1.1e-39 ybjQ S Belongs to the UPF0145 family
NNBOFHNM_01277 2.5e-08
NNBOFHNM_01278 8e-96 V ABC transporter, ATP-binding protein
NNBOFHNM_01279 1.1e-41 gntR1 K Transcriptional regulator, GntR family
NNBOFHNM_01280 6.4e-186 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
NNBOFHNM_01281 4.8e-65 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NNBOFHNM_01282 4.2e-261 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
NNBOFHNM_01283 2.2e-107 terC P Integral membrane protein TerC family
NNBOFHNM_01284 1.6e-38 K Transcriptional regulator
NNBOFHNM_01285 1.3e-95 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NNBOFHNM_01286 4.1e-101 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NNBOFHNM_01287 4.5e-102 tcyB E ABC transporter
NNBOFHNM_01288 7e-28 ponA V the current gene model (or a revised gene model) may contain a frame shift
NNBOFHNM_01289 6.1e-188 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NNBOFHNM_01290 5.9e-303 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NNBOFHNM_01291 4e-210 mtlR K Mga helix-turn-helix domain
NNBOFHNM_01292 9.8e-177 yjcE P Sodium proton antiporter
NNBOFHNM_01293 8.4e-104 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NNBOFHNM_01294 4e-49 dhaM 2.7.1.121 S PTS system fructose IIA component
NNBOFHNM_01295 9.5e-69 dhaL 2.7.1.121 S Dak2
NNBOFHNM_01296 2e-151 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
NNBOFHNM_01297 1.9e-114 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
NNBOFHNM_01298 6.5e-61 K Bacterial regulatory proteins, tetR family
NNBOFHNM_01299 5.9e-210 brnQ U Component of the transport system for branched-chain amino acids
NNBOFHNM_01301 1.7e-111 endA F DNA RNA non-specific endonuclease
NNBOFHNM_01302 4.1e-75 XK27_02070 S Nitroreductase family
NNBOFHNM_01303 1.1e-193 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
NNBOFHNM_01304 3.8e-33 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
NNBOFHNM_01305 4.7e-294 lai 4.2.1.53 S Myosin-crossreactive antigen
NNBOFHNM_01306 9.4e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NNBOFHNM_01307 5.5e-59 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
NNBOFHNM_01308 4.4e-76 azlC E branched-chain amino acid
NNBOFHNM_01309 2e-31 azlD S Branched-chain amino acid transport protein (AzlD)
NNBOFHNM_01310 1.5e-56 ohrR K helix_turn_helix multiple antibiotic resistance protein
NNBOFHNM_01311 1.6e-55 jag S R3H domain protein
NNBOFHNM_01312 6.9e-54 K Transcriptional regulator C-terminal region
NNBOFHNM_01313 7.7e-44 thiT S Thiamine transporter protein (Thia_YuaJ)
NNBOFHNM_01314 3.4e-285 pepO 3.4.24.71 O Peptidase family M13
NNBOFHNM_01315 1.7e-111 dat 2.6.1.21 EH PFAM aminotransferase, class IV
NNBOFHNM_01316 1.7e-09 yvaZ S Protein of unknown function (DUF1648)
NNBOFHNM_01317 2.1e-69 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
NNBOFHNM_01318 3.9e-47 hmpT S ECF-type riboflavin transporter, S component
NNBOFHNM_01319 5.1e-42 wecD K Acetyltransferase GNAT Family
NNBOFHNM_01321 1.2e-253 XK27_06780 V ABC transporter permease
NNBOFHNM_01322 9.3e-95 XK27_06785 V ABC transporter, ATP-binding protein
NNBOFHNM_01324 7.5e-72 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NNBOFHNM_01325 3.1e-59 ytbE S reductase
NNBOFHNM_01326 2.4e-51 ytbE S reductase
NNBOFHNM_01327 4.2e-43 ytcD K HxlR-like helix-turn-helix
NNBOFHNM_01328 1.9e-101 ybbM S Uncharacterised protein family (UPF0014)
NNBOFHNM_01329 2e-67 ybbL S ABC transporter
NNBOFHNM_01330 8.1e-163 oxlT P Major Facilitator Superfamily
NNBOFHNM_01331 6.2e-53 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NNBOFHNM_01332 3.1e-47 S Short repeat of unknown function (DUF308)
NNBOFHNM_01333 1.8e-30 tetR K Transcriptional regulator C-terminal region
NNBOFHNM_01334 4.9e-150 yfeX P Peroxidase
NNBOFHNM_01335 2.5e-16 S Protein of unknown function (DUF3021)
NNBOFHNM_01336 4.5e-39 K LytTr DNA-binding domain
NNBOFHNM_01337 7.6e-113 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
NNBOFHNM_01338 2.2e-209 mmuP E amino acid
NNBOFHNM_01339 1.2e-15 psiE S Phosphate-starvation-inducible E
NNBOFHNM_01340 3.7e-155 oppF P Belongs to the ABC transporter superfamily
NNBOFHNM_01341 1.3e-180 oppD P Belongs to the ABC transporter superfamily
NNBOFHNM_01342 5.8e-170 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
NNBOFHNM_01343 1e-141 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
NNBOFHNM_01344 1.4e-202 oppA E ABC transporter, substratebinding protein
NNBOFHNM_01345 4.5e-218 yifK E Amino acid permease
NNBOFHNM_01346 1.1e-85 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NNBOFHNM_01347 8.2e-55 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
NNBOFHNM_01348 5e-66 pgm3 G phosphoglycerate mutase family
NNBOFHNM_01349 1.5e-251 ctpA 3.6.3.54 P P-type ATPase
NNBOFHNM_01350 3.3e-21 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NNBOFHNM_01351 2e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NNBOFHNM_01352 5.6e-150 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NNBOFHNM_01353 1.2e-21 K transcriptional regulator
NNBOFHNM_01354 5e-77 hchA S intracellular protease amidase
NNBOFHNM_01355 2.8e-135 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
NNBOFHNM_01356 3.1e-112 lacI3 K helix_turn _helix lactose operon repressor
NNBOFHNM_01357 2.3e-68 malL 3.2.1.10 GH13 G Psort location Cytoplasmic, score
NNBOFHNM_01358 1.9e-157 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
NNBOFHNM_01359 2e-39 2.7.1.191 G PTS system fructose IIA component
NNBOFHNM_01360 5.4e-123 G PTS system mannose/fructose/sorbose family IID component
NNBOFHNM_01361 4.4e-101 G PTS system sorbose-specific iic component
NNBOFHNM_01362 2e-64 2.7.1.191 G PTS system sorbose subfamily IIB component
NNBOFHNM_01363 1.9e-80 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
NNBOFHNM_01364 2.8e-139 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NNBOFHNM_01365 2e-201 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
NNBOFHNM_01366 6.5e-117 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
NNBOFHNM_01367 3.4e-197 1.3.5.4 C FMN_bind
NNBOFHNM_01368 2.2e-56 3.1.3.48 K Transcriptional regulator
NNBOFHNM_01369 3.8e-161 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
NNBOFHNM_01370 4.5e-196 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
NNBOFHNM_01371 3.7e-74 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
NNBOFHNM_01372 1.2e-25 yxjG 2.1.1.14 E Methionine synthase
NNBOFHNM_01373 3.9e-86 yxjG 2.1.1.14 E Cobalamin-independent synthase, Catalytic domain
NNBOFHNM_01374 1.6e-100 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NNBOFHNM_01375 2.8e-81 S Belongs to the UPF0246 family
NNBOFHNM_01376 5.6e-10 S CAAX protease self-immunity
NNBOFHNM_01377 3.5e-59 ykhA 3.1.2.20 I Thioesterase superfamily
NNBOFHNM_01378 8.7e-157 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NNBOFHNM_01380 1.6e-230 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NNBOFHNM_01381 5.3e-64 C FMN binding
NNBOFHNM_01382 1.3e-204 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NNBOFHNM_01383 1.7e-54 rplI J Binds to the 23S rRNA
NNBOFHNM_01384 3.9e-263 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NNBOFHNM_01385 4.7e-07
NNBOFHNM_01386 1.8e-217 scrB 3.2.1.26 GH32 G invertase
NNBOFHNM_01387 1.7e-147 scrR K helix_turn _helix lactose operon repressor
NNBOFHNM_01388 5.3e-151 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NNBOFHNM_01389 4.8e-282 fruA 2.7.1.202 GT Phosphotransferase System
NNBOFHNM_01392 9.1e-76 3.1.21.3 V Type I restriction modification DNA specificity domain
NNBOFHNM_01393 1.6e-131 L Belongs to the 'phage' integrase family
NNBOFHNM_01394 1.2e-36 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
NNBOFHNM_01395 1.3e-104 3.1.21.3 V Type I restriction modification DNA specificity domain
NNBOFHNM_01396 8.5e-64 V HNH endonuclease
NNBOFHNM_01398 2e-42 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NNBOFHNM_01399 5.9e-30 L Helix-turn-helix domain
NNBOFHNM_01400 1.5e-208 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
NNBOFHNM_01401 2e-183 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
NNBOFHNM_01402 1.8e-113 ntpJ P Potassium uptake protein
NNBOFHNM_01403 2.2e-58 ktrA P TrkA-N domain
NNBOFHNM_01404 2.1e-53 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
NNBOFHNM_01405 1.1e-43 K helix_turn_helix isocitrate lyase regulation
NNBOFHNM_01406 5.3e-120 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NNBOFHNM_01407 1.8e-102 pfoS S Phosphotransferase system, EIIC
NNBOFHNM_01408 1.4e-19
NNBOFHNM_01409 2e-93 S Predicted membrane protein (DUF2207)
NNBOFHNM_01410 1.2e-54 bioY S BioY family
NNBOFHNM_01411 5.7e-184 lmrB EGP Major facilitator Superfamily
NNBOFHNM_01412 2.5e-95 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NNBOFHNM_01413 7.6e-74 glcR K DeoR C terminal sensor domain
NNBOFHNM_01414 1e-60 yceE S haloacid dehalogenase-like hydrolase
NNBOFHNM_01415 1.9e-41 S CAAX protease self-immunity
NNBOFHNM_01416 1.2e-33 S Domain of unknown function (DUF4811)
NNBOFHNM_01417 2.1e-197 lmrB EGP Major facilitator Superfamily
NNBOFHNM_01418 4.2e-32 merR K MerR HTH family regulatory protein
NNBOFHNM_01419 1.8e-39 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NNBOFHNM_01420 9.1e-71 S Protein of unknown function (DUF554)
NNBOFHNM_01421 6.9e-120 G Bacterial extracellular solute-binding protein
NNBOFHNM_01422 3e-79 baeR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NNBOFHNM_01423 1.6e-100 baeS T Histidine kinase
NNBOFHNM_01424 7e-80 rbsB G sugar-binding domain protein
NNBOFHNM_01425 9e-152 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
NNBOFHNM_01426 6.4e-116 manY G PTS system sorbose-specific iic component
NNBOFHNM_01427 2.1e-147 manN G system, mannose fructose sorbose family IID component
NNBOFHNM_01428 3.2e-52 manO S Domain of unknown function (DUF956)
NNBOFHNM_01429 2.1e-70 mltD CBM50 M NlpC P60 family protein
NNBOFHNM_01430 4.7e-130 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NNBOFHNM_01431 1.6e-163 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NNBOFHNM_01432 2.4e-75 ung2 3.2.2.27 L Uracil-DNA glycosylase
NNBOFHNM_01433 1e-47 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
NNBOFHNM_01434 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NNBOFHNM_01435 3e-106 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NNBOFHNM_01436 6.5e-37 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NNBOFHNM_01437 3.7e-45 S CRISPR-associated protein (Cas_Csn2)
NNBOFHNM_01438 7.8e-38 K transcriptional regulator PadR family
NNBOFHNM_01439 3.2e-19 XK27_06920 S Protein of unknown function (DUF1700)
NNBOFHNM_01440 1.2e-15 S Putative adhesin
NNBOFHNM_01441 2.2e-16 pspC KT PspC domain
NNBOFHNM_01443 5.1e-13 S Enterocin A Immunity
NNBOFHNM_01444 4e-236 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NNBOFHNM_01445 1.3e-260 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
NNBOFHNM_01446 4.3e-100 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NNBOFHNM_01447 1.1e-166 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NNBOFHNM_01448 1.5e-120 potB P ABC transporter permease
NNBOFHNM_01449 4.5e-104 potC U Binding-protein-dependent transport system inner membrane component
NNBOFHNM_01450 1.3e-159 potD P ABC transporter
NNBOFHNM_01451 3.5e-132 ABC-SBP S ABC transporter
NNBOFHNM_01452 3.3e-113 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
NNBOFHNM_01453 6.7e-107 XK27_08845 S ABC transporter, ATP-binding protein
NNBOFHNM_01454 2.8e-66 M ErfK YbiS YcfS YnhG
NNBOFHNM_01455 1.2e-53 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NNBOFHNM_01456 9.4e-224 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NNBOFHNM_01457 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NNBOFHNM_01458 1.2e-102 pgm3 G phosphoglycerate mutase
NNBOFHNM_01459 4.7e-56 S CAAX protease self-immunity
NNBOFHNM_01460 2.2e-47 C Flavodoxin
NNBOFHNM_01461 9.7e-60 yphH S Cupin domain
NNBOFHNM_01462 3.6e-46 yphJ 4.1.1.44 S decarboxylase
NNBOFHNM_01463 2.9e-143 E methionine synthase, vitamin-B12 independent
NNBOFHNM_01464 7.4e-107 metQ1 P Belongs to the nlpA lipoprotein family
NNBOFHNM_01465 1.5e-149 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NNBOFHNM_01466 2.7e-70 metI P ABC transporter permease
NNBOFHNM_01467 3.3e-134 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NNBOFHNM_01468 3e-84 drgA C nitroreductase
NNBOFHNM_01469 2.5e-83 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
NNBOFHNM_01470 1.7e-106 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
NNBOFHNM_01471 8.1e-172 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NNBOFHNM_01472 3.7e-264 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
NNBOFHNM_01474 2.3e-150 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NNBOFHNM_01475 2.4e-31 metI U ABC transporter permease
NNBOFHNM_01476 2.5e-128 metQ M Belongs to the nlpA lipoprotein family
NNBOFHNM_01477 1.8e-53 S Protein of unknown function (DUF4256)
NNBOFHNM_01480 1e-177 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
NNBOFHNM_01481 5.7e-167 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
NNBOFHNM_01482 2.6e-180 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NNBOFHNM_01483 4e-230 lpdA 1.8.1.4 C Dehydrogenase
NNBOFHNM_01484 2.1e-148 lplA 6.3.1.20 H Lipoate-protein ligase
NNBOFHNM_01485 9.2e-56 S Protein of unknown function (DUF975)
NNBOFHNM_01486 5.7e-78 E GDSL-like Lipase/Acylhydrolase family
NNBOFHNM_01487 1.4e-38
NNBOFHNM_01488 4.1e-27 gcvR T Belongs to the UPF0237 family
NNBOFHNM_01489 2.1e-220 XK27_08635 S UPF0210 protein
NNBOFHNM_01490 1.1e-14 ytkL S Beta-lactamase superfamily domain
NNBOFHNM_01491 2e-289 ybiT S ABC transporter, ATP-binding protein
NNBOFHNM_01492 1e-78 2.4.2.3 F Phosphorylase superfamily
NNBOFHNM_01493 1.1e-23
NNBOFHNM_01494 7.6e-112 dkg S reductase
NNBOFHNM_01495 7.7e-19 rimL 1.1.1.25 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NNBOFHNM_01496 2.3e-168 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NNBOFHNM_01497 1.1e-192 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NNBOFHNM_01498 2.1e-46 EGP Transmembrane secretion effector
NNBOFHNM_01499 5.2e-137 purR 2.4.2.7 F pur operon repressor
NNBOFHNM_01500 6.6e-53 adhR K helix_turn_helix, mercury resistance
NNBOFHNM_01501 1.7e-183 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NNBOFHNM_01502 2.5e-104 pfoS S Phosphotransferase system, EIIC
NNBOFHNM_01503 2.2e-126 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NNBOFHNM_01504 4.8e-149 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
NNBOFHNM_01505 1.9e-196 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NNBOFHNM_01506 1.1e-200 argH 4.3.2.1 E argininosuccinate lyase
NNBOFHNM_01508 1.3e-155 amtB P ammonium transporter
NNBOFHNM_01509 2.8e-117 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NNBOFHNM_01510 6.6e-46 argR K Regulates arginine biosynthesis genes
NNBOFHNM_01511 4.2e-134 arcT 2.6.1.1 E Cys/Met metabolism PLP-dependent enzyme
NNBOFHNM_01512 1.7e-90 S Alpha/beta hydrolase of unknown function (DUF915)
NNBOFHNM_01513 1.2e-22 veg S Biofilm formation stimulator VEG
NNBOFHNM_01514 7.5e-134 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NNBOFHNM_01515 1.7e-86 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NNBOFHNM_01516 8.3e-105 tatD L hydrolase, TatD family
NNBOFHNM_01517 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NNBOFHNM_01518 4.3e-127
NNBOFHNM_01519 3.5e-153 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
NNBOFHNM_01520 7.2e-43 VPA1512 ET Bacterial extracellular solute-binding proteins, family 3
NNBOFHNM_01521 2.3e-31 K Transcriptional regulator
NNBOFHNM_01522 3.5e-104 ybhR V ABC transporter
NNBOFHNM_01523 8.4e-83 ybhF_2 V abc transporter atp-binding protein
NNBOFHNM_01524 9.4e-103 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NNBOFHNM_01525 8.8e-171 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
NNBOFHNM_01526 7.9e-127 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NNBOFHNM_01527 2.3e-272 helD 3.6.4.12 L DNA helicase
NNBOFHNM_01529 1.3e-114 htpX O Belongs to the peptidase M48B family
NNBOFHNM_01530 1.5e-71 lemA S LemA family
NNBOFHNM_01531 1.1e-54 L phosphatase homologous to the C-terminal domain of histone macroH2A1
NNBOFHNM_01532 3.2e-45 yjcF K protein acetylation
NNBOFHNM_01534 3.3e-253 yfiC V ABC transporter
NNBOFHNM_01535 1.6e-172 lmrA V ABC transporter, ATP-binding protein
NNBOFHNM_01536 4.6e-37 lmrA V ABC transporter, ATP-binding protein
NNBOFHNM_01537 5.8e-35 K Bacterial regulatory proteins, tetR family
NNBOFHNM_01538 7.3e-246 yhcA V ABC transporter, ATP-binding protein
NNBOFHNM_01539 5.9e-223 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NNBOFHNM_01540 5.7e-39 S VIT family
NNBOFHNM_01541 9.4e-240 sufB O assembly protein SufB
NNBOFHNM_01542 4.9e-41 nifU C SUF system FeS assembly protein, NifU family
NNBOFHNM_01543 3.3e-148 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NNBOFHNM_01544 5.6e-143 sufD O FeS assembly protein SufD
NNBOFHNM_01545 3.6e-116 sufC O FeS assembly ATPase SufC
NNBOFHNM_01546 5.5e-223 E ABC transporter, substratebinding protein
NNBOFHNM_01548 7.7e-20 S protein encoded in hypervariable junctions of pilus gene clusters
NNBOFHNM_01549 2.5e-27 K Helix-turn-helix XRE-family like proteins
NNBOFHNM_01551 9.6e-47 V ABC-2 family transporter protein
NNBOFHNM_01552 1.1e-73 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
NNBOFHNM_01553 1.7e-105 2.7.13.3 T His Kinase A (phosphoacceptor) domain
NNBOFHNM_01554 8.8e-90 KT Transcriptional regulatory protein, C terminal
NNBOFHNM_01555 2.2e-75 spaC2 V Lanthionine synthetase C-like protein
NNBOFHNM_01556 4.3e-184 spaT V ATPases associated with a variety of cellular activities
NNBOFHNM_01557 7.6e-207 spaB S Lantibiotic dehydratase, C terminus
NNBOFHNM_01559 2.5e-136 pfoS S Phosphotransferase system, EIIC
NNBOFHNM_01560 5.5e-117 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
NNBOFHNM_01561 9.1e-63 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
NNBOFHNM_01562 2.4e-36 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
NNBOFHNM_01563 1.4e-136 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
NNBOFHNM_01564 4.8e-83 srlA G PTS system enzyme II sorbitol-specific factor
NNBOFHNM_01565 4.5e-43 gutM K Glucitol operon activator protein (GutM)
NNBOFHNM_01566 5.8e-104 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
NNBOFHNM_01567 4e-110 IQ NAD dependent epimerase/dehydratase family
NNBOFHNM_01568 4.7e-163 ytbD EGP Major facilitator Superfamily
NNBOFHNM_01569 3e-98 fabK 1.3.1.9 S Nitronate monooxygenase
NNBOFHNM_01570 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NNBOFHNM_01571 4.4e-171 tonB M YSIRK type signal peptide
NNBOFHNM_01572 1.4e-61 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain protein
NNBOFHNM_01573 8.3e-126 S Bacteriophage abortive infection AbiH
NNBOFHNM_01576 1.6e-174 spoVK O ATPase family associated with various cellular activities (AAA)
NNBOFHNM_01577 3.5e-50 K Cro/C1-type HTH DNA-binding domain
NNBOFHNM_01579 5.2e-65 S Acetyltransferase (GNAT) domain
NNBOFHNM_01580 5.1e-72 ywlG S Belongs to the UPF0340 family
NNBOFHNM_01581 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NNBOFHNM_01582 2.8e-96 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NNBOFHNM_01583 8.8e-58 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NNBOFHNM_01584 8.2e-177 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
NNBOFHNM_01585 2e-14 ybaN S Protein of unknown function (DUF454)
NNBOFHNM_01586 3.9e-238 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NNBOFHNM_01587 7.2e-200 frdC 1.3.5.4 C FAD binding domain
NNBOFHNM_01588 5.3e-206 yflS P Sodium:sulfate symporter transmembrane region
NNBOFHNM_01589 4.6e-36 yncA 2.3.1.79 S Maltose acetyltransferase
NNBOFHNM_01590 1.4e-162 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NNBOFHNM_01591 8.4e-60 dedA 3.1.3.1 S SNARE associated Golgi protein
NNBOFHNM_01592 1.9e-95 ypuA S Protein of unknown function (DUF1002)
NNBOFHNM_01594 1.4e-113 3.2.1.18 GH33 M Rib/alpha-like repeat
NNBOFHNM_01595 2.1e-116 3.2.1.18 GH33 M Rib/alpha-like repeat
NNBOFHNM_01596 8.1e-44 K Copper transport repressor CopY TcrY
NNBOFHNM_01597 6.1e-60 T Belongs to the universal stress protein A family
NNBOFHNM_01598 5.9e-41 K Bacterial regulatory proteins, tetR family
NNBOFHNM_01599 1.1e-56 K transcriptional
NNBOFHNM_01600 1.8e-71 mleR K LysR family
NNBOFHNM_01601 1.7e-248 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
NNBOFHNM_01602 1.7e-126 mleP S Sodium Bile acid symporter family
NNBOFHNM_01603 5.5e-64 S ECF transporter, substrate-specific component
NNBOFHNM_01604 1.6e-61 acmC 3.2.1.96 NU mannosyl-glycoprotein
NNBOFHNM_01605 9.7e-74 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NNBOFHNM_01606 6.3e-193 pbuX F xanthine permease
NNBOFHNM_01607 1.7e-35 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
NNBOFHNM_01608 9e-255 topB 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
NNBOFHNM_01609 2.5e-94 yjbM 2.7.6.5 S RelA SpoT domain protein
NNBOFHNM_01610 1.3e-116 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NNBOFHNM_01611 7.6e-94 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
NNBOFHNM_01612 1.6e-159 mgtE P Acts as a magnesium transporter
NNBOFHNM_01614 1.7e-40
NNBOFHNM_01615 9.7e-35 K GNAT family
NNBOFHNM_01616 6.4e-209 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
NNBOFHNM_01617 5.5e-221 gdhA 1.4.1.4 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
NNBOFHNM_01618 4.9e-42 O ADP-ribosylglycohydrolase
NNBOFHNM_01619 3.6e-220 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
NNBOFHNM_01620 2.8e-266 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NNBOFHNM_01621 4.2e-161 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NNBOFHNM_01622 1.2e-115 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
NNBOFHNM_01623 4.7e-194 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
NNBOFHNM_01624 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NNBOFHNM_01625 1.2e-175 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
NNBOFHNM_01626 2e-24 S Domain of unknown function (DUF4828)
NNBOFHNM_01627 7e-128 mocA S Oxidoreductase
NNBOFHNM_01628 1.5e-159 yfmL L DEAD DEAH box helicase
NNBOFHNM_01629 2e-20 S Domain of unknown function (DUF3284)
NNBOFHNM_01631 6.2e-277 kup P Transport of potassium into the cell
NNBOFHNM_01632 4.2e-101 malR K Transcriptional regulator, LacI family
NNBOFHNM_01633 4.3e-213 malT G Transporter, major facilitator family protein
NNBOFHNM_01634 1e-78 galM 5.1.3.3 G Aldose 1-epimerase
NNBOFHNM_01635 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
NNBOFHNM_01636 2.4e-84 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
NNBOFHNM_01637 3e-266 E Amino acid permease
NNBOFHNM_01638 3.5e-182 pepS E Thermophilic metalloprotease (M29)
NNBOFHNM_01639 9.3e-169 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NNBOFHNM_01640 1.1e-70 K Sugar-specific transcriptional regulator TrmB
NNBOFHNM_01641 1.7e-122 S Sulfite exporter TauE/SafE
NNBOFHNM_01642 5.2e-120 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
NNBOFHNM_01643 0.0 S Bacterial membrane protein YfhO
NNBOFHNM_01644 8.7e-53 gtcA S Teichoic acid glycosylation protein
NNBOFHNM_01645 5.1e-54 fld C Flavodoxin
NNBOFHNM_01646 1.2e-143 map 3.4.11.18 E Methionine Aminopeptidase
NNBOFHNM_01647 1.2e-152 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NNBOFHNM_01648 2.8e-12 mltD CBM50 M Lysin motif
NNBOFHNM_01649 2.9e-93 yihY S Belongs to the UPF0761 family
NNBOFHNM_01650 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NNBOFHNM_01651 6.8e-26 ykuJ S Protein of unknown function (DUF1797)
NNBOFHNM_01652 1.7e-129 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NNBOFHNM_01653 5.4e-128 cpoA GT4 M Glycosyltransferase, group 1 family protein
NNBOFHNM_01654 8.8e-162 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
NNBOFHNM_01655 2.4e-285 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NNBOFHNM_01656 9.7e-37 ptsH G phosphocarrier protein HPR
NNBOFHNM_01657 1.5e-15
NNBOFHNM_01658 0.0 clpE O Belongs to the ClpA ClpB family
NNBOFHNM_01659 6.6e-23 XK27_09445 S Domain of unknown function (DUF1827)
NNBOFHNM_01660 2.9e-105 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
NNBOFHNM_01661 0.0 rafA 3.2.1.22 G alpha-galactosidase
NNBOFHNM_01662 1.6e-200 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NNBOFHNM_01663 2.3e-163 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NNBOFHNM_01664 2.6e-179 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NNBOFHNM_01665 5.9e-111 galR K Transcriptional regulator
NNBOFHNM_01666 4e-289 lacS G Transporter
NNBOFHNM_01667 0.0 lacL 3.2.1.23 G -beta-galactosidase
NNBOFHNM_01668 5.2e-279 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NNBOFHNM_01669 1.4e-108 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NNBOFHNM_01670 6.5e-158 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NNBOFHNM_01671 3.4e-91 yueF S AI-2E family transporter
NNBOFHNM_01672 2.6e-97 ygaC J Belongs to the UPF0374 family
NNBOFHNM_01673 9.4e-192 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NNBOFHNM_01674 2.9e-68 recX 2.4.1.337 GT4 S Regulatory protein RecX
NNBOFHNM_01675 1.1e-19 yvrI K RNA polymerase sigma factor, sigma-70 family
NNBOFHNM_01676 7e-23 S Cytochrome B5
NNBOFHNM_01677 2.3e-48 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain (presumed)
NNBOFHNM_01678 7.6e-60
NNBOFHNM_01679 1.3e-43 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NNBOFHNM_01680 6.6e-156 nrnB S DHHA1 domain
NNBOFHNM_01681 1.5e-91 yunF F Protein of unknown function DUF72
NNBOFHNM_01682 3.4e-48 ndoA L Toxic component of a toxin-antitoxin (TA) module
NNBOFHNM_01683 5.4e-13
NNBOFHNM_01684 4.8e-146 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NNBOFHNM_01685 1.6e-30 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NNBOFHNM_01686 3.4e-208 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NNBOFHNM_01687 4.1e-179 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NNBOFHNM_01688 4.9e-65 S Uncharacterized protein conserved in bacteria (DUF2263)
NNBOFHNM_01689 7.7e-61 M ErfK YbiS YcfS YnhG
NNBOFHNM_01691 2.6e-84 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NNBOFHNM_01692 1.2e-180 pbuG S permease
NNBOFHNM_01694 1.8e-78 S Cell surface protein
NNBOFHNM_01696 1.9e-256 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
NNBOFHNM_01697 6.3e-61
NNBOFHNM_01698 3.6e-41 rpmE2 J Ribosomal protein L31
NNBOFHNM_01699 5.3e-189 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NNBOFHNM_01700 1e-200 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NNBOFHNM_01702 1.2e-288 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NNBOFHNM_01703 1e-41 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NNBOFHNM_01704 1.8e-32 ywiB S Domain of unknown function (DUF1934)
NNBOFHNM_01705 2e-86 yfeJ 6.3.5.2 F glutamine amidotransferase
NNBOFHNM_01706 3.3e-205 ywfO S HD domain protein
NNBOFHNM_01707 7.5e-88 S hydrolase
NNBOFHNM_01708 2e-105 ydcZ S Putative inner membrane exporter, YdcZ
NNBOFHNM_01709 1.3e-63
NNBOFHNM_01711 1.1e-39 L COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
NNBOFHNM_01712 2.3e-22
NNBOFHNM_01713 3e-56 spoVK O ATPase family associated with various cellular activities (AAA)
NNBOFHNM_01715 2.2e-86 S overlaps another CDS with the same product name
NNBOFHNM_01716 1.8e-124 S overlaps another CDS with the same product name
NNBOFHNM_01717 1.9e-98 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NNBOFHNM_01718 1.1e-41 bCE_4747 S Beta-lactamase superfamily domain
NNBOFHNM_01719 6.3e-212 yfnA E Amino Acid
NNBOFHNM_01720 5.4e-53 zur P Belongs to the Fur family
NNBOFHNM_01721 3e-12 3.2.1.14 GH18
NNBOFHNM_01722 5e-98
NNBOFHNM_01723 1.3e-09
NNBOFHNM_01724 3.7e-102 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NNBOFHNM_01725 1.9e-99 glnH ET ABC transporter
NNBOFHNM_01726 1.2e-85 gluC P ABC transporter permease
NNBOFHNM_01727 9.6e-78 glnP P ABC transporter permease
NNBOFHNM_01728 9e-184 steT E amino acid
NNBOFHNM_01729 6.5e-21 K Acetyltransferase (GNAT) domain
NNBOFHNM_01730 3.2e-146 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
NNBOFHNM_01731 4.5e-54 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
NNBOFHNM_01732 2.5e-78 K rpiR family
NNBOFHNM_01733 4.3e-167 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NNBOFHNM_01734 2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NNBOFHNM_01735 4.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NNBOFHNM_01736 1e-100 rplD J Forms part of the polypeptide exit tunnel
NNBOFHNM_01737 2.9e-39 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NNBOFHNM_01738 4.1e-142 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NNBOFHNM_01739 1e-44 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NNBOFHNM_01740 1.5e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NNBOFHNM_01741 5.2e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NNBOFHNM_01742 6.2e-73 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NNBOFHNM_01743 9e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
NNBOFHNM_01744 8e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NNBOFHNM_01745 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NNBOFHNM_01746 7e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NNBOFHNM_01747 1.3e-91 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NNBOFHNM_01748 4.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NNBOFHNM_01749 2.5e-65 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NNBOFHNM_01750 3.2e-87 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NNBOFHNM_01751 9.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NNBOFHNM_01752 1.3e-82 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NNBOFHNM_01753 2.1e-22 rpmD J Ribosomal protein L30
NNBOFHNM_01754 1e-67 rplO J Binds to the 23S rRNA
NNBOFHNM_01755 4.4e-207 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NNBOFHNM_01756 3.4e-107 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NNBOFHNM_01757 4.8e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NNBOFHNM_01758 2.5e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NNBOFHNM_01759 4.4e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NNBOFHNM_01760 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NNBOFHNM_01761 1.3e-155 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NNBOFHNM_01762 4.8e-53 rplQ J Ribosomal protein L17
NNBOFHNM_01763 1.8e-100 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NNBOFHNM_01764 6.7e-111 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NNBOFHNM_01765 2.8e-108 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NNBOFHNM_01766 2.5e-125 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NNBOFHNM_01767 5.5e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NNBOFHNM_01768 1.1e-60 rpsI J Belongs to the universal ribosomal protein uS9 family
NNBOFHNM_01769 5.7e-28
NNBOFHNM_01770 3.1e-246 yjbQ P TrkA C-terminal domain protein
NNBOFHNM_01771 0.0 helD 3.6.4.12 L DNA helicase
NNBOFHNM_01772 4e-87 devA 3.6.3.25 V ABC transporter, ATP-binding protein
NNBOFHNM_01773 2.6e-109 hrtB V ABC transporter permease
NNBOFHNM_01774 1.9e-33 ygfC K transcriptional regulator (TetR family)
NNBOFHNM_01775 1.4e-85 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
NNBOFHNM_01776 1.1e-277 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NNBOFHNM_01777 6.8e-35 M LysM domain protein
NNBOFHNM_01778 9.8e-115 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NNBOFHNM_01779 7.9e-106 sbcC L Putative exonuclease SbcCD, C subunit
NNBOFHNM_01780 7.6e-58 S LexA-binding, inner membrane-associated putative hydrolase
NNBOFHNM_01781 7.2e-53 perR P Belongs to the Fur family
NNBOFHNM_01782 1.1e-207 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NNBOFHNM_01783 1.4e-141 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NNBOFHNM_01784 2.5e-86 S (CBS) domain
NNBOFHNM_01785 4.8e-158 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NNBOFHNM_01786 2.2e-75 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NNBOFHNM_01787 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NNBOFHNM_01788 1.2e-139 yabM S Polysaccharide biosynthesis protein
NNBOFHNM_01789 3.6e-31 yabO J S4 domain protein
NNBOFHNM_01790 1e-21 divIC D Septum formation initiator
NNBOFHNM_01791 1.1e-40 yabR J RNA binding
NNBOFHNM_01792 1.9e-96 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NNBOFHNM_01793 1.5e-76 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NNBOFHNM_01794 3e-282 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NNBOFHNM_01795 6.8e-130 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NNBOFHNM_01796 1.6e-169 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NNBOFHNM_01797 5.1e-260 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NNBOFHNM_01798 2.6e-29 yqkB S Belongs to the HesB IscA family
NNBOFHNM_01799 2.3e-65 yxkH G Polysaccharide deacetylase
NNBOFHNM_01800 2.1e-08
NNBOFHNM_01801 2.2e-53 K LysR substrate binding domain
NNBOFHNM_01802 2e-122 MA20_14895 S Conserved hypothetical protein 698
NNBOFHNM_01803 1.1e-199 nupG F Nucleoside
NNBOFHNM_01804 1.8e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NNBOFHNM_01805 2.2e-49 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NNBOFHNM_01806 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
NNBOFHNM_01807 2.1e-204 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NNBOFHNM_01808 3.9e-159 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NNBOFHNM_01809 9e-20 yaaA S S4 domain protein YaaA
NNBOFHNM_01810 9.3e-153 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NNBOFHNM_01811 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NNBOFHNM_01812 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NNBOFHNM_01813 4.8e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
NNBOFHNM_01814 3.3e-63 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NNBOFHNM_01815 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NNBOFHNM_01816 2.5e-110 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
NNBOFHNM_01817 7.3e-117 S Glycosyl transferase family 2
NNBOFHNM_01818 7.4e-64 D peptidase
NNBOFHNM_01819 0.0 asnB 6.3.5.4 E Asparagine synthase
NNBOFHNM_01820 3.7e-37 yiiE S Protein of unknown function (DUF1211)
NNBOFHNM_01821 3.3e-12 yiiE S Protein of unknown function (DUF1211)
NNBOFHNM_01822 1.6e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NNBOFHNM_01823 7.4e-248 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NNBOFHNM_01824 3.6e-17 yneR
NNBOFHNM_01825 1.5e-230 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NNBOFHNM_01826 2.2e-224 yxbA 6.3.1.12 S ATP-grasp enzyme
NNBOFHNM_01827 3.1e-106 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NNBOFHNM_01828 3.8e-152 mdtG EGP Major facilitator Superfamily
NNBOFHNM_01829 3.8e-14 yobS K transcriptional regulator
NNBOFHNM_01830 2.8e-109 glcU U sugar transport
NNBOFHNM_01831 4.4e-170 yjjP S Putative threonine/serine exporter
NNBOFHNM_01832 2.4e-69 2.3.1.178 J Acetyltransferase (GNAT) domain
NNBOFHNM_01833 2.2e-96 yicL EG EamA-like transporter family
NNBOFHNM_01834 3.5e-223 pepF E Oligopeptidase F
NNBOFHNM_01835 1.5e-108 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NNBOFHNM_01836 4.4e-179 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NNBOFHNM_01837 1.1e-139 gldA 1.1.1.6 C Iron-containing alcohol dehydrogenase
NNBOFHNM_01838 8.4e-62 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NNBOFHNM_01839 4e-23 relB L RelB antitoxin
NNBOFHNM_01841 2.9e-172 S Putative peptidoglycan binding domain
NNBOFHNM_01842 1.2e-31 K Transcriptional regulator, MarR family
NNBOFHNM_01843 3.1e-216 XK27_09600 V ABC transporter, ATP-binding protein
NNBOFHNM_01844 1.1e-229 V ABC transporter transmembrane region
NNBOFHNM_01846 3.3e-96 S Domain of unknown function DUF87
NNBOFHNM_01848 6.3e-85 yxeH S hydrolase
NNBOFHNM_01849 9e-114 K response regulator
NNBOFHNM_01850 1.1e-272 vicK 2.7.13.3 T Histidine kinase
NNBOFHNM_01851 4.6e-103 yycH S YycH protein
NNBOFHNM_01852 5.6e-80 yycI S YycH protein
NNBOFHNM_01853 1.8e-30 yyaQ S YjbR
NNBOFHNM_01854 1.3e-116 vicX 3.1.26.11 S domain protein
NNBOFHNM_01855 3.7e-145 htrA 3.4.21.107 O serine protease
NNBOFHNM_01856 1.5e-72 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NNBOFHNM_01857 4.4e-40 1.6.5.2 GM NAD(P)H-binding
NNBOFHNM_01858 3.3e-25 K MarR family transcriptional regulator
NNBOFHNM_01859 5.9e-88 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
NNBOFHNM_01860 1.7e-46 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NNBOFHNM_01861 4.2e-208 G glycerol-3-phosphate transporter

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)